bluuebunny/crossref_metadata_2025_split huggingface dataset:
Processed Dietary Fiber Partially Hydrolyzed Guar Gum Increases Susceptibility to Colitis and Colon Tumorigenesis in Mice
Authors: Tian Sangshan , Goand Umesh K , Paudel Devendra , Le Giang V. , Tiwari Amit K. , Prabhu K. Sandeep , Singh Vishal 
Published: December 2024

Abstract

The vital role of naturally occurring dietary fibers (DFs) in maintaining intestinal health has fueled the incorporation of isolated DFs into processed foods. A select group of soluble DFs, such as partially hydrolyzed guar gum (Phgg), are being promoted as dietary supplements to meet recommended DF intake. However, the potential effects of regular consumption of these processed DFs on gastrointestinal health remain largely unknown. The present study assessed the impact of Phgg on the development of intestinal inflammation and colitis-associated colon carcinogenesis (CAC). Wild-type C57BL/6 mice were fed isocaloric diets containing either 7.5% Phgg and 2.5% cellulose (Phgg group) or 10% cellulose (control) for four weeks. To induce colitis, a subgroup of mice from each group was switched to 1.4% dextran sulfate sodium (DSS) in drinking water for seven days. CAC was induced in another subgroup through a single dose of azoxymethane (AOM, 7.5 mg/kg i.p.) followed by three DSS/water cycles. To our surprise, Phgg feeding exacerbated DSS-induced colitis, as evidenced by body weight loss, disrupted colonic crypt architecture, and increased pro-inflammatory markers accompanied by a decrease in anti-inflammatory markers. Additionally, Phgg feeding led to increased colonic expression of genes promoting cell proliferation. Accordingly, extensive colon tumorigenesis was observed in Phgg-fed mice in the AOM/DSS model, whereas the control group exhibited no visible tumors. To investigate whether reducing Phgg has a distinct effect on colitis and CAC development, mice were fed a low-Phgg diet (2.5% Phgg). The low-Phgg group also exhibited increased colitis and tumorigenesis compared to the control, although the severity was markedly lower than in the regular Phgg (7.5%) group, suggesting a dose-dependent effect of Phgg in colitis and CAC development. Our study reveals that Phgg supplementation exacerbates colitis and promotes colon tumorigenesis, warranting further investigation into the potential gastrointestinal health risks associated with processed Phgg consumption.
Description Electronic Dictionary in Kurdish Language
Authors: Jawhar Iman Askandar , Muhammadamin Media Murad 
Published: December 2024

This research is an attempt to reveal information about dictionary, how dictionary first emerged in the world and among the Kurdish and who created the first dictionaries. Every language a dictionary in order to survive.
Every language has many types of dictionaries, dictionaries are created in all aspects of life, such as sociology, psychology, language, literature, etc., but the most important thing is that the types of dictionaries are in terms of content and appearance, which includes several types. Therefore, we refer to this type of electronic dictionary in terms of appearance, and content.
The study is divided into two parts: The first part is a theoretical overview of dictionary, which include concept and definition of dictionary. Moreover, information is provided in general about dictionary, the history of dictionary in the world and Kurdish, and dictionary writing and types of dictionaries. The second part is devoted to the analysis of the electronic dictionary, special emphasis is placed on all the electronic dictionaries that contain Kurdish language that are available for users. Data is provided about the dictionaries up to the end of 2023. Then the characteristics of Kurdish dictionary are presented. Finally, the suggestions and the results are presented in several points. Then the sources are listed.
Understanding Dystonia: A Summary of the Basics
Authors: Chisholm Olivia 
Published: December 2024

Abstract
Dystonia is a neurological movement disorder characterised by abnormal and involuntary twisting movements and postures. It comes in many forms and can affect various parts of the body. Dystonia is seen in children and adults as a standalone condition, or as one part of a complex disease. Dystonia can be caused by genetic mutations, specific medications, environmental and chemical factors, or, as in the majority of cases, the cause is unknown. There is currently no cure or disease modifying agent for dystonia, so treatments are aimed at managing symptoms and maintaining quality of life. The treatment options for dystonia include invasive surgeries, medications, botulinum toxin and non-pharmaceutical therapies. Dystonia is often a misunderstood and misdiagnosed disorder, which makes diagnosis difficult. The diagnosis of dystonia is usually made by a Neurologist who specialises in Movement Disorders. Research is ongoing to better understand the disorder and aims to find more effective and efficient treatments, and ultimately a cure for dystonia.
Myotonic dystrophy Type 1: exploring the health care experiences of people living with DM1. A Research Protocol
Authors: O’Maley Karen A 
Published: December 2024

Abstract
This article outlines a research protocol for investigating the health care experiences of people living with Myotonic Dystrophy Type 1 (Dytrophia Myotonica; DM1).

Introduction
DM1 is a neuromuscular condition of highly variable presentation across the lifespan. It is a complex and variable condition which impacts many body systems. Care consensus, clinical experience and scientific genetic findings dominate much of the literature. Findings from the literature indicate health care input from multiple disciplines is recommended to help identify and prevent or minimise disability and early mortality. It is these recommendations for intense health care input and the perceptions people living with DM1 have of their health care that have prompted this enquiry.

Objectives
Investigate the experiences of health care from 3 different groups: people living with DM1, their family members, carers or support people, and health care providers. Potentially illuminating what we as nurses and health care providers do well or not so well.

Intended methods
Guided by Merleau-Ponty’s phenomenology of perception and triangulate these gathered experiences to ascertain if there is convergence or divergence between health care experiences of recipients and providers. This research will utilise a qualitative approach with methodology drawn from phenomenology. Semi-structured Interviews will be conducted with 3 different groups to gain insight into perceptions, experiences, and outcomes of health care interactions. People living with DM1, family members, carers and friends and health professionals providing services and care for people living with DM1 will be invited to participate.
Prevention and management of agitation in the neuroscience patient: Recommendations from Australasia
Authors: Jameson Chantelle , Goff Hannah , Kivunja Stephen , Wilkinson Debbie , Tevaga Sia Telesia , hunter Danniele , Cooke Jenna , Woon Caroline 
Published: December 2024

Abstract

Background
Neuroscience patients can present with agitation due to a number of factors such as the presence of cerebral abnormalities, tumours, trauma, or medications. Agitation among neuroscience patients that escalates to violence and aggression appears to be increasing and highly challenging for neuroscience nursing practice across Australasia. Neuroscience wards or units endeavour to effectively manage patients who are affected by agitation and provide appropriate training for clinical and non-clinical staff. Following a workshop through Australasian Neuroscience Nurses’ Association (ANNA), a group of neuroscience nurses, passionate about improving the care of neuroscience patients presenting with agitation and the safety of the staff; collaborated and researched the most effective prevention and management strategies that can be used to ensure that care delivery for these patients is therapeutic and effective.

Purpose
The purpose of this paper is to share recommendations that can guide the prevention and management of agitation among neuroscience patients from the perspective of neuroscience nurses in Australasia.

Discussion
These recommendations have been discussed from hospitals across Australasia including Perth, Brisbane, Sydney, Canberra, Melbourne, and Wellington in the hope that other cities can make changes in their own hospitals to inform neuroscience nurses and allied clinicians, improve guidelines and provide effective education for staff members that interact with neuroscience patients.
Apomorphine subcutaneous titration in Parkinson’s disease - the effectiveness and safety of apomorphine challenges: A Literature Review
Authors: Jones Amy E , Tune Elise M 
Published: December 2024

Abstract
This review examined the body of evidence to determine the efficacy of an apomorphine challenge. Its primary objective is to identify the dose of the most common adverse events involved with apomorphine challenges. The secondary objective is to determine whether a titration challenge is warranted prior to commencing Apomorphine therapy or an alternate option, such as slow titration, is more efficacious.
Results: The literature review was developed using the Cochrane handbook of systematic reviews. The search yielded 157 results, only 23 were included in the final analysis. Evidence is largely lacking and traditionally anecdotal and based on clinician experience. Studies inadequately control for reporter and rater bias, have small sample sizes; high level evidence is lacking.
Continuous rates range between 2-4mg/hr (Deleu, 2004) and an intermittent dose range between 4mg- 6 mg (Pahwa et al 2007); doses higher than this are likely to induce side effects. QT interval prolongation is linked with both apomorphine and domperidone use and an electrocardiogram (ECG) should be performed prior to commencing both medications.
A positive result for an apomorphine challenge is determined when there is a 20% improvement from baseline score in part III of the Movement Disorder Society – Unified Parkinson’s Disease Rating Scale (MDS- UPDRS), 30 minutes after a dose is given.
Lastly, review examines a theoretical way to titrate patients using the Tomlinson levodopa conversion.
Concussion Video—Educating Schools
Authors: Evans-Roach Vicki. J. 
Published: December 2024

Abstract
Concussion awareness became a priority for the Northern Sydney Local Health District as the increase in children, teenagers, and young adults with concussion, had an effect on emergency department (ED) presentations, follow-up, schooling and sports-related activities. Education in some of the local schools from the Neuroscience Clinical Nurse Consultant had been occurring, but the need far outweighed the in-person approach. Therefore, it was decided that the development of an educational concussion video for schools was required.

AIM
To produce a 5-minute educational video for use in schools in the PDHPE Program / Sport sessions, that could then be broken down into shorter 1-minute versions for social media bursts.

METHOD
A focus group was established and the process of devising and parenting this video took approximately 11months. It is pitched at a 12-year-old and combines animation and realistic scenes.

OUTCOME
The video can be found at - https://vimeo.com/674645370

It has been sent to and accessed by schools within the Northern Sydney Local Health District and has been integrated into the NSW Education Department teacher training as a tool for teachers and students. It has been accessed throughout NSW, other Australian states and accepted for use in the New Zealand schooling system.
Neurological Assessment: Practice Review’
Authors: Jameson Chantelle E , Butler Jordyn A 
Published: December 2024

ABSTRACT

Background statement
Accurate completion of a Neurological Assessment including the Glasgow Coma Scale (GCS) is of the upmost importance in identifying and escalating neurological deterioration. This assessment must be standardised to ensure patient safety and quality care.

Aim
This paper aims to review the standardisation of the GCS inclusive of a comprehensive Neurological Assessment in metropolitan hospitals in Australia. Existing literature on this tool in clinical practice, will be further explored in this review. It will primarily focus on efficacy, standardisation and accuracy of completing a Neurological Assessment on an Adult.

Methods
A comprehensive review of the topic was undertaken, to reveal literature that supports the aim of this paper. Medline and Embase were accessed, with the use of Boolean operators to ensure literature met the inclusion and exclusion criteria.

Results
Five articles were selected as appropriate and relevant to meet the needs and expectations of this review. Research suggests inconsistency and validity of the tool, which may affect patient safety.
Huntington’s Australia – a New National Association to Support the Huntington’s Community
Authors: Thompson Elizabeth , Glasson Christopher 
Published: December 2024

ABSTRACT
Huntington’s disease (HD) is a rare, progressive, neuropsychiatric disorder that is inherited. Although there are treatment options for some of the symptoms, currently there is no cure, despite much research. In addition to medical, nursing and allied health care, a person with HD needs a great deal of support. Until now, this support, for individuals and their families, has been facilitated by Huntington’s Disease Associations in each Australian state and territory. It has been a long-held dream to merge these Associations to form a national body, so as to provide better and more equitable support, increased resources, greater sustainability and create consistent educational material for everyone impacted by HD. The ultimate goal is to help people impacted by the condition live their best life. This dream is about to be realised as 5 states and 2 territories will merge to create Huntington’s Australia, planning to begin operations later this year. The journey over the last 3 years towards this dream is described in this paper.
Microbiological characterization of drinking water and socio-environmental study in the peri-urban area of La Plata, Buenos Aires, Argentina
Authors: Falcone Andrea Celina , Assandri Matias Hernán , Helman María Elisa , Córdoba Joaquín Alejandro , Vetere Virginia , Unzaga Juan Manuel 
Published: December 2024

ABSTRACT

The aim was to analyze the groundwater quality and evaluate the socio-environmental factors associated with the indicators of environmental contamination in the peri-urban area of La Plata. A descriptive cross-sectional study was conducted between 2013 and 2023, and six neighborhoods were selected. Water samples were taken according to the Argentine Food Code and a parasitological analysis of the water was performed using ultrafiltration. Socio-environmental analyses were carried out with semi-structured questionnaires and a generalized linear model was used considering a binomial distribution. Of the total water samples, 70% (75/106) indicated that the water is not suitable for consumption. The highest contamination by total coliforms was observed in Abasto, and the risk of contamination by this indicator was higher (odds ratio &gt; 5) compared to other neighborhoods. A moderate percentage of fecal coliforms and Escherichia coli was found in Melchor Romero and El Peligro, although it was higher than that detected in the other neighborhoods. Pseudomonas spp. was observed in all the samples in Arana and in moderate amounts in Abasto and Lisandro Olmos. Entamoeba spp. and Blastocystis spp. were found in a quarter of the water samples. It is essential to manage environmental sanitation and family health access policies.
Comparative analysis of water quality index based on seasonal differences in the upstream Citarum watershed
Authors: Marselina Mariana , Putri Shefira Herlindya , Nurhayati Siti Ai 
Published: December 2024

ABSTRACT
The Upstream Citarum Watershed is the largest watershed in West Java Province that supports the activities and livelihoods of its surrounding communities. Thus, continuous monitoring of the Citarum River's water quality is essential, with the water quality index (WQI) as an effective tool for assessing its status. Various methods can be used, such as the National Sanitation Foundation WQI (NSF-WQI), the Prati index, and the Dinius index. This study aims to compare these three methods based on secondary data in the form of water quality data from the Regional Environmental Management Agency of West Java Province (2013–2022) collected at four monitoring points, namely, Wangisagara, Koyod, the area after the wastewater treatment plant (WWTP) at Cisirung, and Nanjung. Additionally, primary data from sampling conducted at the same monitoring points were analyzed. The data obtained were categorized based on wet–dry months, wet–dry years, monitoring points, and monitoring years. Based on this study, the water quality status of the Upper Citarum River Basin was obtained in the form of 'Good' and 'Moderate' by the NSF-WQI method; 'Excellent', 'Acceptable', 'Slightly Polluted', and 'Polluted' by the Prati index method; and 'Excellent', 'Good', 'Moderate', 'Bad', and 'Very Bad' by the Dinius index method.
Groundwater quality assessment for drinking and irrigation: A case study in the Cauvery River Basin (CRB) of Tiruchirappalli District, Tamil Nadu, India
Authors: U. P. Meghanad , V. Vasanthamohan , S. Selvakumar 
Published: December 2024

ABSTRACT

The long-term impacts of human activities on groundwater quality in the Cauvery River Basin are not well understood, particularly the combined effects of urbanization, industrialization, and agriculture. Seasonal factors, such as precipitation and water-table fluctuations, also influence groundwater chemistry, affecting its suitability for drinking and irrigation. This research aims to assess the hydrochemical characteristics of groundwater and evaluate its long-term suitability for these purposes, considering both natural and anthropogenic factors. A total of 56 groundwater samples were collected and analyzed for various physicochemical and biochemical parameters. The results showed that the most prevalent ions are bicarbonate (27.3%), chloride (24.1%), and calcium (16.6%), followed by sulfate, magnesium, sodium, and others. The Piper and Gibbs plots indicated that most groundwater samples belong to the mixed calcium chloride facies, and rock–water interaction is the dominant natural mechanism, with some anthropogenic influences, respectively. The GIS-based drinking water quality index (DWQI) map showed that 66% of the samples were of excellent to good quality for drinking without treatment, while the remaining samples were of moderate quality and nearly unsuitable for drinking, requiring further treatment. However, most of the groundwater samples were suitable for irrigation based on irrigation water quality indices.
Mapeamento de superfícies impermeáveis no Oeste da Bahia utilizando algoritmo de Aprendizado de Máquina
Authors: Sousa Gustavo Gonçalves de , Moreira Elvis Bergue Mariz , Pacheco Admilson da Penha , Alves Fabio Corrêa , Ferreira Henrique dos Santos 
Published: December 2024

A superfície impermeável urbana é um parâmetro relevante nas mudanças climáticas, ambientais e na sustentabilidade, sendo fundamental na detecção da qualidade ambiental urbana. O mapeamento dessas superfícies possibilita mensurar o nível de urbanização em que uma cidade se encontra, além de gerar indicativos de impactos sociais, econômicos e ambientais. Porém, poucos estudos aplicaram imagens de satélite de alta resolução espacial para a análise de cidades com significativo crescimento urbano nos últimos anos, sobretudo no oeste baiano. Este trabalho tem como objetivo mapear as áreas impermeáveis da cidade de Barreiras–BA a partir de imagens CBERS 4A e do algoritmo de aprendizado de máquina Random Forest (RF). As bandas espectrais do visível obtidas na data de 13/06/2023 foram usadas como base para a realização de composição colorida e fusão de imagens para obtenção de pixels com 2 m. A imagem fusionada foi classificada com o (RF) e validada através da matriz de confusão, acurácia global e índice Kappa. Os resultados mostraram que na cidade de Barreiras 41,11% correspondem à superfícies impermeáveis. As métricas de exatidão encontradas foram de 0,79 para o Índice Kappa e 91,7% de Acurácia Global. Os resultados encontrados poderão ser base para futuras pesquisas sobre mapeamento do uso e ocupação do solo em perímetros urbanos.
Alveolar Ridge Augmentation using Customized Zirconia Membranes: A Systematic Review
Authors: Albash Ziad , Khalil Ali , Kashkash Wajih 
Published: December 2024

Background
Since the inception of intraosseous implants, the significance of alveolar bone volume has become crucial in formulating treatment plans for dental implants. Various barrier membranes have been extensively employed in alveolar ridge reconstruction, highlighting their efficacy. Recent advancements include the fabrication of customized barrier membranes using multiple materials, with titanium and zirconia being prominent choices. The objective of this study was to conduct a comprehensive review of all clinical studies, case reports, and case series that utilized customized zirconia membranes for alveolar ridge augmentation.

Methods
An electronic literature search was performed to find relevant clinical studies, case reports, and case series published in English up to August 2024. The following keywords used in the search were customized zirconia membrane, alveolar ridge augmentation, Guided bone regeneration, zirconia sheet, ceramic sheet, and Personalized membrane. The quality assessment was conducted using the Joanna Briggs Institute (JBI) critical appraisal checklist specific to each type of study.

Results
The electronic search initially yielded 539 articles. Following deduplication, 263 unique articles remained. Subsequent manual screening of titles and abstracts led to the exclusion of 250 articles, resulting in 13 remaining articles. After conducting a thorough full-text assessment of these 13 articles to verify adherence to the inclusion/exclusion criteria, 6 articles were further excluded, leaving a total of 7 articles included in this review.

Conclusion
While all studies included in this review were case series or case reports, customized zirconia membranes have demonstrated effectiveness in the literature for alveolar ridge augmentation, facilitating the placement of dental implants in all cases with relatively low complication rates, particularly membrane exposure. There is currently no literature evidence supporting the superiority of zirconia over other materials used in customized fabrication, nor is there evidence of superior design or preferred bone grafting under these membranes.