bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating the impact of atmospheric forcing and air–sea coupling on near-coastal regional ocean prediction
Authors: Lewis Huw W. , Siddorn John , Castillo Sanchez Juan Manuel , Petch Jon , Edwards John M. , Smyth Tim 
Published: June 2019

Abstract. Atmospheric forcing applied as ocean model boundary conditions can
have a critical impact on the quality of ocean forecasts. This paper assesses
the sensitivity of an eddy-resolving (1.5 km resolution) regional ocean
model of the north-west European Shelf (NWS) to the choice of atmospheric forcing
and atmosphere–ocean coupling. The analysis is focused on a month-long
simulation experiment for July 2014 and evaluation of simulated sea surface
temperature (SST) in a shallow near-coastal region to the south-west of the
UK (Celtic Sea and western English Channel). Observations of the ocean and
atmosphere are used to evaluate model results, with a particular focus on the
L4 ocean buoy from the Western Channel Observatory as a rare example of
co-located data above and below the sea surface. The impacts of differences in the atmospheric forcing are illustrated by
comparing results from an ocean model run in forcing mode using operational
global-scale numerical weather prediction (NWP) data with an ocean model run
forced by a convective-scale regional atmosphere model. The value of
dynamically representing feedbacks between the atmosphere and ocean state is
assessed via the use of these model components within a fully coupled
ocean–wave–atmosphere system. Simulated SSTs show considerable sensitivity to atmospheric forcing and to the
impact of model coupling in near-coastal areas. A warm ocean bias relative to
in situ observations in the simulation forced by global-scale NWP (0.7 K in
the model domain) is shown to be reduced (to 0.4 K) via the use of the
1.5 km resolution regional atmospheric forcing. When simulated in coupled
mode, this bias is further reduced (by 0.2 K). Results demonstrate much greater variability of both the surface heat budget
terms and the near-surface winds in the convective-scale atmosphere model data,
as might be expected. Assessment of the surface heat budget and wind forcing
over the ocean is challenging due to a scarcity of observations. However, it can be demonstrated that the wind speed over the ocean simulated by the
convective-scale atmosphere did not agree as well with the limited number of observations
as the global-scale NWP data did. Further partially coupled
experiments are discussed to better understand why the degraded wind forcing
does not detrimentally impact on SST results.
The Book Circle: Black Women Readers and Middlebrow Taste in Chicago, 1943–1953
Authors: Unger Mary I. 
Published: June 2019

ABSTRACT
This article offers a case study of the Book Circle, a black women's reading group on Chicago's South Side, from 1943 to 1953. It demonstrates how the group recruited literary reception—specifically middlebrow taste—as a way to lobby for racial equality in the postwar era. In doing so, the Book Circle makes visible a group of twentieth-century black readers historically rendered invisible, as Elizabeth McHenry and others have shown. In this way, this article argues, recovering the Book Circle helps us further document the legacy of black women readers—from nineteenth-century literary clubs to black feminist consciousness-raising groups in the 1960s through the 1980s—who turned to reading as a strategy for social transformation.
O recurso aos memes em diferentes padrões de gêneros à luz da Linguística Textual
Authors: Cavalcante Mônica Magalhães , De Oliveira Rafael Lima 
Published: June 2019

A presente pesquisa propõe descrever e definir a prática linguageira dos memes na internet, analisando-os a partir dos critérios definidores dos gêneros do discurso segundo os pressupostos de Bakhtin, de Miller, de Bazerman e de Rojo, para compreender como e com que propósito surgiram os memes, e como estes se constituem em um percurso histórico na internet. Para tanto, utilizaremos os pressupostos teóricos de Bakhtin (2003) e Bazerman (2009) e a noção de gêneros emergentes de Marcuschi (2004) e Lima-Neto (2014), além da compreensão dos processos intertextuais com base em Cavalcante, Carvalho e Faria (2017). A partir de nossa análise, argumentamos que, por coerência com a noção de gênero que sustentamos, os memes não poderiam constituir um único e mesmo gênero do discurso, pois podem compor uma diversidade de práticas discursivas, nem todas com uma nomeação estabilizada socialmente.
Palavras-chave: Gêneros discursivos; Meme; Viralização; Intertextualidade
Karl Frederik Kinch - a Danish Pioneer in Thessaloniki
Authors: Kiilerich Bente 
Published: June 2019

The Danish archaeologist and philologist Karl Frederik Kinch (1853-1921) is probably best known for his investigations on Rhodes, where, together with Christian Blinkenberg, he led the excavations on the acropolis of Lindos between 1902 and 1905. This article focuses on another aspect of Kinch’s research: his pioneering work on the Arch of Galerius in Thessaloniki. By studying the iconography of the sculpted reliefs, Kinch could show that the monument was not, as then generally believed, erected in honour of Alexander the Great or Constantine. He was, in fact, the first to establish that the arch celebrated the Emperor Galerius’ victory over the Sasanian Persians in 297/98. Kinch published his results in L’Arc de triomphe de Galère (Paris 1890), which is also the first monograph on the monument. I here take a closer look at this publication, and tries to situate it within the researcher’s life and work. rchaeologist and philologist Karl Frederik Kinch
Medialiseringens litteratur?
Authors: Svendsen Erik 
Published: June 2019

Anmeldelse af Tore Rye Andersen, Jørgen Bruhn, Nina Christensen, Stefan Kjerkegaard, Sara Tanderup Linkis, Birgitte Stougaard Pedersen og Hans Kristian Rustad (red.): Litteratur mellem medier. 384 sider. Aarhus Universitetsforlag, Aarhus, 2018
Combining epidural fentanyl and lidocaine for postoperative pain
Authors: Lytle Sue A. , Goldsmith Douglas M. , Neuendorf Tracy L. 
Published: June 2019

Abstract
Fifteen patients undergoing total hip and total knee replacement were studied prospectively to evaluate postoperative pain relief provided by an epidural infusion of fentanyl citrate, with and without lidocaine hydrochloride, and changes in arterial flow to the lower extremities. The patients were randomly placed in three groups: group 1 received epidural fentanyl, 5 j.Lg/mL; group 2 received epidural fentanyl, 5 j.Lg/mL with 0.75% solution of lidocaine; and group 3 received epidural fentanyl, 5 j.Lg/mL with 1.0% solution of lidocaine. All patients received 1.5% solution of epidural etidocaine hydrochloride with epinephrine 1:200,000 for intraoperative anesthesia. No clinical evidence of deep vein thrombosis, tachyphylactic reaction to lidocaine, orthostatic hypotension, or motor block was demonstrated in any patient. The addition of lidocaine to the epidural fentanyl infusion did not improve pain relief or allow a decrease in the rate of infusion. Patients in all groups had improved arterial flow to the lower extremities 24 hours postoperatively.
Fishing for vaccines againstVibrio choleraeusingin silicopan-proteomic reverse vaccinology approach
Authors: Rashid Muhammad I. , Rehman Sammia , Ali Amjad , Andleeb Saadia 
Published: June 2019

BackgroundCholera, an acute enteric infection, is a serious health challenge in both the underdeveloped and the developing world. It is caused byVibrio choleraeafter ingestion of fecal contaminated food or water. Cholera outbreaks have recently been observed in regions facing natural calamities (i.e., earthquake in Haiti 2010) or war (i.e., ongoing civil war in Yemen 2016) where healthcare and sanitary setups have been disrupted as a consequence. Whole-cell oral cholera vaccines (OCVs) have been in market but their regimen efficacy has been questioned. A reverse vaccinology (RV) approach has been applied as a successful anti-microbial measure for many infectious diseases.MethodologyWith the aim of finding new protective antigens for vaccine development, theV. choleraeO1 (biovar eltr str. N16961) proteome was computationally screened in a sequential prioritization approach that focused on determining the antigenicity of potential vaccine candidates. Essential, accessible, virulent and immunogenic proteins were selected as potential candidates. The predicted epitopes were filtered for effective binding with MHC alleles and epitopes binding with greater MHC alleles were selected.ResultsIn this study, we report lipoproteinNlpD, outer membrane proteinOmpU, accessory colonization factorAcfA, Porin, putative and outer membrane proteinOmpWas potential candidates qualifying all the set criteria. These predicted epitopes can offer a potential for development of a reliable peptide or subunit vaccine forV. cholerae.
Farmers’ Knowledge, Attitude and Practice (KAP) Regarding Nitrogen Fortified Organic Manure in Crop Production
Authors: Das Monoj Kumar , Islam Md. Matiul , Billah Md. Maruf 
Published: June 2019

The study was carried out mainly to evaluate the knowledge, attitude and practice (KAP) of farmers regarding nitrogen fortified organic manure. Data were collected from purposive-randomly selected 120 farmers from Kharnia, Atalia, Maguraghona unions of Dumuria upazila under Khulna district of Bangladesh through personal interview using an interview schedule during January to February, 2019. There were eleven personal socioeconomic characteristics of farmers selected for the study which were age, educational qualification, family size, farming experience, organic farming experience, annual income, farm size, organizational participation, agricultural training, cosmopolitanism, extension contact regarding nitrogen fortified organic manure, were treated as independent variables, whereas knowledge, attitude, practice (KAP) and faced problems were considered as dependent variables. Majority (65%) of the respondents had high knowledge, most of the respondents (85.8%) had medium favorable attitude and majority of the respondents (65.8%) had medium practice, respectively, regarding nitrogen fortified organic manure. 65% of the respondents encountered medium problem while preparing and applying nitrogen fortified organic manures in the crop field. Although farmers usually use inorganic nitrogen fertilizer but they have favorable attitude regarding nitrogen fortified organic manure. On the basis of the response provided by the respondents’ positive statements ranked first and negative statements ranked second in gross considerations. The 1st position was ranked by the individual statement “N fortified organic manure is good” on the basis of obtained highest score (532), which was followed by “soil health is maintained” (2nd, score 530) and “great source of income” (3rd, score 488). Among the selected characteristics of farmers, annual income showed negative significant relationship with attitude while farm size, agricultural training showed positive significant relationship; and family size showed negative significant relationship with knowledge of farmers regarding nitrogen fortified organic manure. Cosmopolitanism and extension contact showed positive significant relationship with practice; while agricultural training showed negative significant relationship with problem of farmers regarding nitrogen fortified organic manure. Thus, the high knowledge, medium favorable attitude and medium practice should be utilized to design appropriate extension strategies for production and application of the nitrogen fortified organic manures by the farmers in their agricultural fields for crop production. The encountered problems also should be addressed properly to ensure timely mitigation. Proper measures should also be undertaken to make nitrogen fortified organic manure popular day by day.
Influence of Coral-reef Complexity on Species Richness and the Hierarchical Structuration of Species Abundances in Reef fish Communities: A Case Study in South-east Brazil
Authors: Béguinot Jean 
Published: June 2019

Growing complexity of coral habitat is expected to increase resource partitioning among co-occurring reef fish and, thereby, reduce to some extent the mean competitive intensity. This will have associated consequences on the internal structuring of species in reef fish communities, in particular regarding species richness and evenness of species abundances. Accumulating dedicated case studies are necessary, however, to get further empirical confirmations. The present analysis aims to contribute in this respect, comparing reef fish communities associated to two coral-reef settings that markedly differ in their degree of morphological complexity, at Itaipu Sound, Brazil. As the available samplings of these communities remained incomplete, numerical extrapolations were implemented, thereby providing least-bias estimates for both total species richness and the exhaustive distribution of species abundances in both compared reef fish communities. As expected, total species richness increases with greater degree of coral habitat complexity, while the unevenness of species abundances decreases. This decrease in abundance unevenness – reflecting the corresponding relaxation of the mean level of competitive intensity – is partly due to the direct, negative influence of species richness on abundance unevenness, as an overall trend. Beyond that, however, the relaxation is further strengthened by an additional “genuine” contribution – this time independent from the variation in species richness – and, as such, directly and idiosyncratically attached to the improvement in habitat complexity.
Anisotropic Thermal Conductive Composite by the Guided Assembly of Boron Nitride Nanosheets for Flexible and Stretchable Electronics
Authors: Hong Haeleen , Jung Yei Hwan , Lee Ju Seung , Jeong Chanho , Kim Jong Uk , Lee Sori , Ryu Hyewon , Kim Heyn , Ma Zhenqiang , Kim Tae‐il 
Published: June 2019

AbstractOwing to the growing demand for highly integrated electronics, anisotropic heat dissipation of thermal management material is a challenging and promising technique. Moreover, to satisfy the needs for advancing flexible and stretchable electronic devices, maintaining high thermal conductivity during the deformation of electronic materials is at issue. Presented here is an effective assembly technique to realize a continuous array of boron nitride (BN) nanosheets on tetrahedral structures, creating 3D thermal paths for anisotropic dissipation integrated with deformable electronics. The tetrahedral structures, with a fancy wavy shaped cross‐section, guarantee flexibility and stretchability, without the degradation of thermal conductivity during the deformation of the composite film. The structured BN layer in the composites induces a high thermal conductivity of 1.15 W m−1 K−1 in the through‐plane and 11.05 W m−1 K−1 in the in‐plane direction at the low BN fraction of 16 wt%, which represent 145% and 83% increases over the randomly mixing method, respectively. Furthermore, this structured BN composite maintains thermal dissipation property with 50% strain of the original length of composite. Various electronic device demonstrations provide exceptional heat dissipation capabilities, including thin film silicon transistor and light‐emitting diode on flexible and stretchable composite, respectively.
Photoredox‐Catalyzed Tandem Demethylation of N,N‐Dimethyl Anilines Followed by Amidation with α‐Keto or Alkynyl Carboxylic Acids
Authors: Das Pritha , Begam Hasina Mamataj , Bhunia Samir Kumar , Jana Ranjan 
Published: June 2019

AbstractWe report herein, a biomimetic approach for highly selective monodemethylation of N,N‐dimethyl anilines to generate secondary amines and subsequent coupling with α‐ketocarboxylic acids or alkynyl carboxylic acids to form α‐ketoamides or alkynamides respectively under visible light photoredox catalyst in a single operation. From the deuterium‐labeling experiment, it was probed that demethylation is the slowest step in this tandem process. Whereas, control experiments and spectroscopic studies revealed that photoredox catalyst is also involved in the subsequent amidation step. The reaction proceeds smoothly at room temperature providing moderate to excellent yield of the coupling products. The amides have also been converted to a series of biologically active spiro compounds.magnified image
Pharmacokinetic interference of doxorubicin with tolbutamide due to reduced metabolic clearance with increased serum unbound fraction in rats
Authors: Fukuno Shuhei , Nagai Katsuhito , Yamamoto Kohei , Tanimura Takehiro , Nabe Takeshi , Konishi Hiroki 
Published: June 2019

AbstractThe study examined the effect of doxorubicin (DOX) on the hepatic expression of CYP2C and its activity for metabolizing tolbutamide (TB), a specific CYP2C substrate, in rats and whether the pharmacokinetics of tolbutamide were altered by doxorubicin exposure. The expression level of hepatic CYP2C11 was depressed 1 day after doxorubicin administration (day 1), and this effect on CYP2C11 was augmented on day 4. However, the expression level of hepatic CYP2C6 remained unchanged. The activity of tolbutamide 4‐hydroxylation in hepatic microsomes was decreased with time following doxorubicin administration. Regarding the enzyme kinetic parameters for tolbutamide 4‐hydroxylation on day 4, the maximum velocity (Vmax) was significantly lower in the DOX group than that in the control group, while the Michaelis constant (Km) was unaffected. On pharmacokinetic examination, the total clearance (CLtot) of tolbutamide on day 4 was increased, despite the decreased metabolic capacity. On the other hand, the serum unbound fraction (fu) of tolbutamide was elevated with a reduced serum albumin concentration in the DOX group. Contrary to CLtot, CLtot/fu, a parameter approximated to the hepatic intrinsic clearance of unbound tolbutamide, was estimated to be significantly reduced in the DOX group. These findings indicate that the metabolic capacity of CYP2C11 in the liver is depressed time‐dependently by down‐regulation after doxorubicin exposure in rats, and that the decreased enzyme activity of TB 4‐hydroxylation in hepatic microsomes reflects the pharmacokinetic change of unbound tolbutamide, not total tolbutamide, in serum.
Development and full validation of an HPLC methodology to quantify atorvastatin and curcumin after their intranasal co‐delivery to mice
Authors: Silva Jessica , Basso João , Sousa João , Fortuna Ana , Vitorino Carla 
Published: June 2019

AbstractThere is increasing interest in atorvastatin and curcumin owing to their potential anticancer activity. A new, accurate and sensitive HPLC method was developed, for the first time, to simultaneously quantify atorvastatin and curcumin in mouse plasma and brain, liver, lung and spleen tissues following protein precipitation sample preparation. The chromatographic separation was achieved in 13 min on a C18 column, at 35°C, using a mobile phase composed of acetonitrile–methanol–2% (v/v) acetic acid (37.5:2.5:60, v/v/v) at a flow rate of 1.0 mL/min. The detection of analytes and internal standard was carried out at 247, 425 and 250 nm, respectively. According to international guidelines, the method was shown to be selective, with lower limits of quantification ranging from 10 to 500 ng/mL for curcumin, and from 100 to 600 ng/mL for atorvastatin, linear over a wide concentration range (r2 ≥ 0.9971) and with acceptable accuracy (bias ± 12.29%) and precision (coefficient of variation ≤13.15%). The analytes were reproducibly recovered at a percentage >81.10% and demonstrated to be stable under various experimental conditions in all biological matrices. This method can be easily applied to in vivo biodistribution studies related to the intranasal administration of atorvastatin and curcumin, separately or simultaneously.
Chemisorption of NO2 to MoS2 Nanostructures and its Effects for MoS2 Sensors
Authors: Huang Jialiang , Chu Jifeng , Wang Zhenyu , Zhang Jinying , Yang Aijun , Li Xin , Gao Chen , Huang Hongyang , Wang Xiaohua , Cheng Yonghong , Rong Mingzhe 
Published: June 2019

AbstractThe special interactions with NO2 make MoS2 promising sensors. Effective gas adsorption and active sites of MoS2 are crucial for high performance sensors. However, studies of the interactions of MoS2 with gas have been focused on the physisorption of basal planes. In this article, chemisorption modes, with O,O‐bidentate or N‐monodentate bonding, on the (1–1 0) surfaces of MoS2 structures have been explored in addition to physisorption. The active sites of MoS2 nanosensors have been predicted to be edge sites of (1–1 0) surfaces and further confirmed by the different sensing performances of vertically and parallelly aligned MoS2 hybrids. Chemisorption mode with N‐monodentate bonding has also been calculated to be effective for MoS2 nanosensors by a two‐probe system simulation and further confirmed by in‐situ Raman and in‐situ diffuse reflectance infrared Fourier transform experiments. High sensitivity and selectivity have also been obtained by the vertical aligned MoS2 hybrids.
Numerical approach for generic three‐phase flow based on cut‐cell and ghost fluid methods
Authors: Dang Son Tung , Meese Ernst Arne , Morud John Christian , Johansen Stein Tore 
Published: June 2019

SummaryIn this paper, we introduce numerical methods that can simulate complex multiphase flows. The finite volume method, applying Cartesian cut‐cell is used in the computational domain, containing fluid and solid, to conserve mass and momentum. With this method, flows in and around any geometry can be simulated without complex and time consuming meshing. For the fluid region, which involves liquid and gas, the ghost fluid method is employed to handle the stiffness of the interface discontinuity problem. The interaction between each phase is treated simply by wall function models or jump conditions of pressure, velocity and shear stress at the interface. The sharp interface method “coupled level set (LS) and volume of fluid (VOF)” is used to represent the interface between the two fluid phases. This approach will combine some advantages of both interface tracking/capturing methods, such as the excellent mass conservation from the VOF method and good accuracy of interface normal computation from the LS function. The first coupled LS and VOF will be generated to reconstruct the interface between solid and the other materials. The second will represent the interface between liquid and gas.