bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment of Patients With Early-Stage Colorectal Cancer: ASCO Resource-Stratified Guideline
Authors: Costas-Chavarri Ainhoa , Nandakumar Govind , Temin Sarah , Lopes Gilberto , Cervantes Andres , Cruz Correa Marcia , Engineer Rena , Hamashima Chisato , Ho Gwo Fuang , Huitzil Fidel David , Malekzadeh Moghani Mona , Sharara Ala I. , Stern Mariana C. , Teh Catherine , Vázquez Manjarrez Sara E. , Verjee Azmina , Yantiss Rhonda , Shah Manish A. 
Published: February 2019

PURPOSE To provide resource-stratified, evidence-based recommendations on the treatment and follow-up of patients with early-stage colorectal cancer. METHODS ASCO convened a multidisciplinary, multinational Expert Panel that reviewed existing guidelines and conducted a modified ADAPTE process and a formal consensus process with additional experts for one round of formal ratings. RESULTS Existing sets of guidelines from 12 guideline developers were identified and reviewed; adapted recommendations from six guidelines form the evidence base and provide evidence to inform the formal consensus process, which resulted in agreement of 75% or more on all recommendations. RECOMMENDATIONS For nonmaximal settings, the recommended treatments for colon cancer stages nonobstructing, I-IIA: in basic and limited, open resection; in enhanced, adequately trained surgeons and laparoscopic or minimally invasive surgery, unless contraindicated. Treatments for IIB-IIC: in basic and limited, open en bloc resection following standard oncologic principles, if not possible, transfer to higher-level facility; in emergency, limit to life-saving procedures; in enhanced, laparoscopic en bloc resection, if not possible, then open. Treatments for obstructing, IIB-IIC: in basic, resection and/or diversion; in limited or enhanced, emergency surgical resection. Treatment for IIB-IIC with left-sided: in enhanced, may place colonic stent. Treatment for T4N0/T3N0 high-risk features or stage II high-risk obstructing: in enhanced, may offer adjuvant chemotherapy. Treatment for rectal cancer cT1N0 and cT2n0: in basic, limited, or enhanced, total mesorectal excision principles. Treatment for cT3n0: in basic and limited, total mesorectal excision, if not, diversion. Treatment for high-risk patients who did not receive neoadjuvant chemotherapy: in basic, limited, or enhanced, may offer adjuvant therapy. Treatment for resectable cT3N0 rectal cancer: in enhanced, base neoadjuvant chemotherapy on preoperative factors. For post-treatment surveillance, a combination of medical history, physical examination, carcinoembryonic antigen testing, imaging, and endoscopy is performed. Frequency depends on setting. Maximal setting recommendations are in the guideline. Additional information can be found at www.asco.org/resource-stratified-guidelines . NOTICE It is the view of the American Society of Clinical Oncology that health care providers and health care system decision makers should be guided by the recommendations for the highest stratum of resources available. The guidelines are intended to complement but not replace local guidelines.
Death Wish
Authors: Huneke Samuel Clowes 
Published: February 2019

AbstractThis article analyzes the relationship between suicide and homosexual discourses in modern Germany. Considering literature, gay periodicals, mainstream newspapers, letters, plays, and poetry, it asks how authors came to correlate homosexuality so strongly with a propensity to commit suicide. In particular, the article makes out a dialectical relationship among three discursive tropes of gay suicide. Doctors and activists of the nineteenth century, including the sexologist Magnus Hirschfeld, employed gay suicide to call for the abolition of Germany’s ban on male sodomy. In opposition thereto, masculinist writers depicted gay suicide sympathetically. Weimar-era literature synthesized these diametric trends into a ubiquitous narrative of gay suicide, which would color mainstream representations of homosexuality and perpetuate the stereotype that gay people are destined to have tragic lives of misery and self-inflicted death. This article argues that the suicide stereotype played a significant role in the formation of modern gay discourses and that its influence remains strong even today.
Sunlit Dancers
Authors: Satterthwaite Tim 
Published: February 2019

AbstractThe German photo-illustrated magazine UHU, launched in 1924, was known for its risqué photography of the female nude. These photos offered, however, more than mere titillation: images of pastoral nudes, and of naked dancers, were a sublime expression of UHU’s cult of youth and physicality and of visual beauty in the natural and manmade world. Significantly, the magazine’s eclectic visual culture—which also embraced images of male gymnastics and of children—inflected the ideological conflicts that centered on the unclothed body in this period. The article describes how contrasting ideas of the body, and of social order, are symbolically expressed in poses and pictorial settings. In particular, the grouping of figures, in geometric and informal “human patterns,” speaks to a fundamental dichotomy in Weimar modernism: the divide between machine-based (rationalist) ideologies and “spiritualized” visions of an organic social order. UHU’s sunbathers and expressive dancers embodied the dynamic tensions of the new technological society—tensions that would resolve, with drastic consequences, in the following decade.
A Novel Benzimidazole-Based Fluorescence Probe for Detecting Zinc Ion in Aqueous Solution and Zebrafish
Authors: Yun Jin Yeong , Kim Ahran , Hwang Suh Mi , Yun Dongju , Lee Hyojin , Kim Ki-Tae , Kim Cheal 
Published: February 2019

Abstract
A novel selective and sensitive chemosensor, (E)-1-((((1H-benzo[d]imidazol-2-yl)methyl)imino)methyl)naphthalen-2-ol (BIN), was developed for fluorescence detection of Zn2+. The compound BIN acts as a fluorescent “turn-on” detector for Zn2+. The limit of detection (2.26 µM) for zinc ion is well below the WHO standard (76.0 µM). Probe BIN can be chemically reversible with ethylenediaminetetraacetic acid (EDTA). The binding mechanism of BIN with zinc ion was demonstrated by fluorescence, UV-visible, electrospray ionization mass spectroscopy, 1H NMR titration and calculations. Importantly, probe BIN could be applied to determine zinc ion in water samples and living zebrafish.
Selective Extraction of Zr(IV) over Hf(IV) from Aqueous Hydrochloric Acid with p-tert-Butylcalix[4]arenediphosphonic Acid
Authors: Morohashi Naoya , Kato Yutaka , Sumida Sahoko , Kurusu Yu , Hattori Tetsutaro 
Published: February 2019

Abstract
p-tert-Butylcalix[4]arenediphosphonic acid (L) extracts Zr(IV) and Hf(IV) from aqueous HCl, H2SO4, and H3PO4. In the extraction from aqueous HCl of different concentrations, the percentage of extraction (E%) of Hf(IV) decreases notably with an increase in acid concentration (96% at 0.5 M HCl and 12% at 7 M HCl), whereas the E% of Zr(IV) remains at a moderate level (90% at 0.5 M HCl and ∼60% at 7 M HCl). Thus, selective extraction of Zr(IV) over Hf(IV) is achieved from high-concentration HCl solutions. The separation factor (SZr) reaches 24 when using two molar equiv of L to Zr(IV) at 7 M HCl. Mechanistic studies indicate that L extracts Zr(IV) from high-concentration HCl solutions by a solvation mechanism by forming a 1:1 complex, LZrCl4. Back extraction of Zr(IV) proceeds quantitatively by treating the organic phase with 5 M H3PO4 after the extraction of Zr(IV).
Di(acenaphtho)BODIPYs and Dipyrrins as Dyes with Deep-Red To NIR Absorptions
Authors: Uno Hidemitsu , Hirose Mako , Honda Takayuki , Mori Shigeki , Takase Masayoshi , Okujima Tetsuo 
Published: February 2019

Abstract
Di(acenaphtho)-fused BODIPYs with four electron-withdrawing N,N-dimethylcarbamoyl groups were obtained by complexation of the corresponding dipyrrins, which were also proven to be a stable deep-red dye.
Using a Monte Carlo Simulation Exercise to Teach Principles of Distribution: An Enhanced Version of the Classic Transportation Problem
Authors: Weltman David , Tokar Travis 
Published: February 2019

This paper explains a Monte Carlo simulation workshop applied to an extended version of the classic transportation problem. It is designed to be conducted in a classroom or laboratory where students have access to a Monte Carlo simulation tool, such as Oracle Crystal Ball. The hands-on exercise builds on the classic transportation problem by allowing students to develop cost-efficient solutions when demands are uncertain and follow multiple types of patterns. Students develop a distribution plan by considering transportation, inventory-holding, and stock-out costs. Through simulation, students are able to see the consequences of their proposed policies and revise them until reaching a satisfactory solution. The Monte Carlo method is deployed because traditional deterministic optimization models do not exist for our scenario that we believe to be realistic and widely applicable. Students gain valuable experience using an important modeling tool applied to a classic operations-management problem. Data are available at https://doi.org/10.1287/ited.2018.0200 .
Oral and dental management for people with lymphoma
Authors: Abed Hassan , Nizarali Najla , Burke Mary 
Published: February 2019

Abstract: A lymphoma is a solid neoplasm that arises in lymphoid tissues and spreads to distant lymphoid glands and organs. Functional lymphocytes circulate the body in the lymphatic system as a part of the immune system. In lymphoma, proliferated abnormal lymphocytes collect in the lymphatic glands and organs with variant signs and symptoms based on the affected site. There are two main types of lymphoma: Hodgkin's lymphoma (HL) and non-Hodgkin's lymphoma (NHL), with different subtypes. The major aetiology is still unknown. Varying treatment modalities are available including monoclonal antibodies, chemotherapy, radiotherapy, corticosteroids and haematopoietic stem cell transplant (HSCT). These have acute and longer-term side-effects that affect clinical decision-making for dental treatment. Therefore, people with lymphoma benefit from a pre-treatment dental assessment and should have regular follow-up in primary care. CPD/Clinical Relevance: This paper aims to provide dental care providers in the primary care setting, community dental service or hospital dental setting with knowledge to manage patients diagnosed with lymphoma.
A case of florid pregnancy gingivitis
Authors: Hua Lewis , Locke Matthew 
Published: February 2019

Abstract: The aim of this case is to demonstrate an exaggerated appearance and subsequent management of a florid combination of pregnancy gingivitis and multiple pregnancy epulides. Pregnancy-associated periodontal conditions constitute benign overgrowth that histologically may be indistinguishable from pyogenic granulomata. The literature has described presentation from the first trimester, peaking in the third trimester before an amount of spontaneous resolution post-partum. This paper describes a 26-year-old woman at 33 weeks of gestation who was referred for significant generalized enlarged gingivae with accompanying soreness and discomfort in oral function. Florid gingivitis and epulis represents important periodontal manifestations during pregnancy and can be troublesome in providing meaningful immediate pain relief. CPD/Clinical Relevance: The dental clinician should be aware of pregnancy-associated gingivitis/epulis, the aetiology, presentation and be able to provide necessary steps for diagnosis, treatment and referral pathways in the primary care setting. These lesions should always be included in the differential diagnosis of oral mucosal soft tissue masses.
A Função da Capacidade Dinâmica na Construção da Inovação Disruptiva: um Estudo de Caso da Primeira Empresa de Mediação 100% Online no Brasil
Authors: Silveira Júnior Mauricio José Da , Rezende da Costa Priscila , Ribeiro Lucas Daniel Ramos 
Published: February 2019

Este artigo tem o objetivo descrever o processo da criação da primeira empresa de mediação online do Brasil – Mediação Online (MOL) e as etapas do processo de mediação online de conflitos, como exemplo do uso da inovação como forma de desafogar o poder judiciário e estimular a solução rápida de lides, através do processo de mediação de conflitos num negócio digital. Através da sanção da lei 13.140/2015 a mediação foi regulamentada e este processo ganhou uma nova escala de eficiência com a aplicação das ferramentas de mediação através do uso da plataforma digital. Foi utilizado o método qualitativo de caráter exploratório, optando por um estudo de caso único através de entrevistas à fundadora e cofundadora, observação e avaliação documental. O artigo potencialmente contribui para demonstrar como o uso de algumas capacidades dinâmicas da empresa podem ser direcionadas para a construção da inovação disruptiva aplicadas ao negócio digital
DESCRIPCIÓN DE PATRONES NORMALES Y ANORMALES DE PLÁNTULAS DE Juglans nigra
Authors: FLORES P. , POGGI D. , GARCIA S. , CATRARO M. , GARIGLIO N. 
Published: February 2019

Juglans nigra en una especie de relevancia económica y con un elevado nivel industrial y tecnológico cultivándose por su madera, como portainjerto del nogal europeo, y por sus frutos para la alimentación humana. En la Prueba de Germinación Estándar, y en diferentes pruebas para determinar el vigor de las semillas los resultados se expresan en Porcentaje de Plántulas Normales. El objetivo de este trabajo fue describir patrones de plántulas normales y anormales de J. nigra como herramientas para ser utilizadas en todas aquellas pruebas que expresan sus resultados en porcentaje de plántulas normales.
Se describieron las categorías: Normales Vigorosas (plántulas libres de lesiones), Normales Débiles (plántulas con defi ciencias o lesiones leves) y Anormales con defectos a nivel de raíz y epicótile.
Temporal Variations in Fungal Bioaerosols in Outdoor Environment: A Three Year Study at Four Different Locations in Gwalior, Central India
Authors: Kumar Pramod , Goel Ajay 
Published: February 2019

Abstract Airborne fungi may cause a variety of health problems in human and animals. In this study, a survey of fungal bioaerosols was done for three years during 2007-2009 in Central India. Air samples were collected from four different locations at Gwalior, Central India on monthly basis. Results showed that fungal bioaerosols concentrationranged from 550 to 7363 CFU/m3 at different sites. Significant higher bioaerosols content was observed during the year 2008 and 2009 than 2007. Highest mean fungal concentration (2687.86 CFU/m3) was found at a public garden, whereas lowest mean concentration (1722.72 CFU/m3) was observed at civil hospital. A seasonal rhythm was observed in the level of airborne fungi. Maximal fungal count was observed in winter followed by monsoon and lowest in summers. Among meteorological factors, statistically significant negative correlation was found with temperature and wind speed. During the study, a total of 41 fungal species belonging to 21 genera were identified. Alternaria, Aspergillus, Cladosporium, Curvularia, Fusarium, Penicillium, Phoma and Trichothecium were the dominated genera. Several identified fungal species viz. Alternaria alternata, Aspergillus flavus, Aspergillus niger,Penicillium citrinum, Penicillium chrysogenum, Fusarium moniliforme, Trichoderma harzianum and Rhizopus stolonifer from the studied area are well known for causing allergy or production of mycotoxin.
Determinación de la incertidumbre del método de análisis de aflatoxinas por HPLC en pasa de uva
Authors: Martínez Nora Dolores , Rodríguez Ana María , Gutiérrez Aída Rosa , Di Carlo Vitolino Marina Daniela , Durán Analía De los Ángeles 
Published: February 2019

Contexto: En este trabajo se presenta la determinación de las incertidumbres de los métodos de análisis de aflatoxinas B1, B2, G1 y G2 en pasa de uva por HPLC-FLD. La incertidumbre de un método es uno de los parámetros requeridos por la norma IRAM 301-ISO/IEC 17025:2005, de aplicación en la República Argentina y acreditada por el Organismo Argentino de Acreditación (OAA). Forma parte de la validación del método analítico. Es un requisito necesario para ampliar el alcance de acreditación del Laboratorio de Análisis de Productos Regionales de Ingeniería Química (LAPRIQ), perteneciente al Instituto de Ingeniería Química de la Universidad Nacional de San Juan.
Metodología: El procedimiento utilizado es el denominado bottom up, basado en una sucesión de etapas de cálculo que tienen en cuenta los errores provenientes de cada una de las operaciones analíticas descompuestas en actividades primarias. La etapa inicial consiste en la identificación de las fuentes de error que pueden afectar el resultado del análisis. Se tomño como base para la determinación de las fuentes de error, y su incidencia en la incertidumbre final del proceso, el procedimiento de espina de pescado de Ishikawa. Definidos los factores que suman al error en la medición, se realizaron todos los ensayos de calibración del HPLC, índice de recuperación y verificación del instrumental para la determinación de la incertidumbre estándar de los subcomponentes. Se calculó luego la incertidumbre combinada teniendo en cuenta los aportes individuales. Posteriormente se sumaron las incertidumbres combinadas, ponderadas según la importancia de su contribución a través del coeficiente de sensibilidad. Por último, se determinó la incertidumbre expandida usando un factor de cobertura K = 2, que implica un porcentaje de confianza del 95 %. Con este factor se puede esperar que se incluya la mayor fracción de la distribución de los valores atribuidos al mesurando.
Resultados: Se detectaron seis fuentes de error, correspondientes a las mediciones de: masa de la muestra, volúmenes de extracción, elución y alícuota para clean up, detección en HPLC e índice de recuperación del método. Las incertidumbres expandidas calculadas de las cuatro aflatoxinas son AFB1= 0,7mg/kg, AFB2= 0,2mg/kg, AFG1 = 0,9 mg/kg y AFG2 = 0,3 mg/kg.
Conclusiones: Los valores de las incertidumbres expandidas se informan en el certificado de análisis, junto con el resultado del ensayo por HPLC, como una de las pruebas de la validación del método.
Simulación numérica CFD de la estructura de control y del sistema de compuertas radiales - represa El Quimbo
Authors: Ladino Moreno Edgar Orlando , Santos Granados Germán Ricardo , García-Ubaque César Augusto 
Published: February 2019

Contexto: Describir matemáticamente el comportamiento hidráulico en estructuras de control conlleva a ecuaciones diferenciales acopladas no lineales, las cuales no cuentan con solución analítica en la mayoría de los problemas de ingeniería. No obstante, es posible obtener soluciones aproximadas a partir del método de volúmenes finitos (FVM). Este método convierte un medio continuo con variables infinitas en un medio discreto con geometrías establecidas y condiciones de contorno determinadas.
Método: Se desarrolló un modelo numérico en 2D sin considerar el efecto de las pilas y los estribos en el azud, a escala 1:70, bajo condiciones de flujo permanente de la estructura de control y del sistema de compuertas radiales de la represa El Quimbo, a partir de la implementación el software Ansys Fluent 17.0. El análisis hidrodinámico de la estructura se realizó bajo condiciones de superficie libre y con diferentes cargas hidráulicas, para aperturas de 704 msnm, 706,9 msnm, 709,4 msnm, 712 msnm y 724,6 msnm Posteriormente, se validó el modelo numérico a partir de la comparación de los resultados numéricos con los datos teóricos realizados por Ingetec y los datos de las pruebas realizadas en el modelo físico desarrollado por la Universidad Nacional de Colombia (sede Manizales).
Resultados: Para un periodo de retorno de 100 años, el modelo numérico estimó una lámina de 0,0306 m que corresponden a 2,143 m en la estructura El Quimbo. Con esta disposición, ingresó al volumen de control un total de 80,7996 L/s y salieron 80,7324 L/s, originando una variación de caudal de 0,08316 %. La mayor variación de lámina de agua del modelo numérico con respecto a la lámina observada es de 3,1 % (0,258 m), la cual corresponde a la creciente máxima probable para una apertura de compuertas con cota (724,6 msnm) y con una descarga de 290 L/s. De igual forma, las mayores velocidades desarrolladas por el flujo en el vertedero se originan en la salida del deflector, correspondiente a la abscisa K0+ 5,19 m. Según el modelo numérico, se determinó que el impacto del chorro en el canal se hace con una velocidad máxima de 6,15 m/s.
Conclusiones: La relación entre la carga hidráulica con respecto a la carga de diseño no debe superar 1,33, lo cual a su vez concuerda con lo recomendado por la USBR. Asimismo, la condición de cavitación encontrada en la rápida puede ser considerada cavitación incipiente. En el diseño de vertederos, la relación H/HD incide de manera directa en la aparición de fenómenos de cavitación sobre la estructura, en el desarrollo de altas velocidades en la rápida, en el deflector y en la capacidad de descarga del vertedero.
IMPLEMENTASI DETEKSI PLAGIARISME MENGGUNAKAN METODE N-GRAM DAN JACCARD SIMILARITY TERHADAP ALGORITMA WINNOWING
Authors: Sunardi Sunardi , Yudhana Anton , Mukaromah Iif Alfiatul 
Published: February 2019

Fenomena plagiarisme dalam dunia akademik bukanlah hal yang baru di Indonesia, perguruan tinggi di Indonesia sudah cukup lama dicemari oleh tindak plagiarisme. Dengan didukungnya kemajuan teknologi yang semakin canggih, salah satunya jaringan internet yang mendunia, memudahkan, cepat, praktis dan murah. Sehingga banyak orang lebih memilih menggunakan internet untuk menyelesaikan tugasnya seperti membuat karya ilmiah dengan cara copy-paste karya orang lain dari internet tanpa menyebutkan sumber yang digunakan untuk menyelesaikan tugasnya. Hal tersebut bisa diatasi secara dini menggunakan metode n-gram untuk mengambil potongan karakter huruf pada dokumen yang akan dicocokan dan Jaccard similarity untuk menghitung berapa persen kesamaan pada sebuah dokumen yang diproses menggunakan algoritma winnowing. Algoritma winnowing merupakan algoritma yang digunakan untuk mencocokan karakter huruf atau angka pada dua dokumen dengan teknik hashing. Kata kunci: N-gram, Jaccard Similarity, Algoritma Winnowing.
TECHNIKA KOMUNIKOWANIA PRAWA W DECYZJACH I ZARZĄDZENIACH ADMINISTRACYJNYCH
Authors: LIZISOWA Maria Teresa 
Published: February 2019

The article is a linguistic lecture on mutual relations between legal language and legislative language on the semantic, syntactic, pragmatic and stylistic planes. The author analysed decisions and official regulations with regard to the status of language as well as the linguistic understanding of communication. A decisive official act is a testimony of the primary reading of the text of a legislative act by an official, fulfilling the role of an interpreter and a decision maker in applying law. He fulfils a duty imposed on him by the norm of competence, verbalised in principles of legal acts. In the process of organizing a legal text, he makes use of the rules of language, according to both the studied and the statutorily recommended rules of the interpretations of law. Through evoking the content of legal articles in official documents, therefore through concretization of legal norms in the process of reception, the legal meanings and contexts undergo a certain kind of assimilation by an official-interpreter. Later, they become adapted in corresponding legal situations, and finally, as a consequence, a process of universalization of knowledge about the established law takes place, because an official-decision maker inscribes his personal knowledge of the legislative content into a specific legal reality of his own community.