bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostics in anaemia of chronic disease in general practice: a real-world retrospective cohort study
Authors: Schop Annemarie , Stouten Karlijn , van Houten Ron , Riedl Jürgen , van Rosmalen Joost , Bindels Patrick JE , Levin Mark-David 
Published: July 2018

BackgroundLimited research has been performed that focused on the diagnosis of the underlying cause of anaemia of chronic disease (ACD) in general practice or on prevalence data of the underlying causes of ACD in general practice, although this is one of the most common types of anaemia.AimTo clarify the diagnostic strategies of GPs in patients newly diagnosed with ACD and to determine the most common underlying causes.Design & settingRetrospective cohort study.MethodPatients newly diagnosed with ACD were selected based on laboratory criteria. ACD was defined as confirmed anaemia and ferritin levels above 100 μg/l combined with decreased iron and/or reduced transferrin. Additional medical information on patients was obtained from the electronic medical files of the GP and/or the referral hospital.ResultsOf the 267 analysed patients with ACD, additional investigations were performed in 205 patients (77%); in 31 patients (12%) the cause was apparent at the time of diagnosis, and for 31 patients (12%) no additional investigations were requested. In 210 (79%) of the 267 patients, an underlying cause was established, with infection (n = 68, 32%), autoimmune disease (n = 51, 24%) and malignancy (n = 48, 23%) as the most frequently observed etiologies. In 35 (13%) of the ACD patients, oral iron supplementation was prescribed by the GP. This was mainly done in patients with severe anaemia or less enhanced ferritin levels.ConclusionFor most patients with newly diagnosed ACD, the GP undertakes additional investigations to establish underlying causes. However, the cause of ACD remains unknown in a small proportion of patients. The use of oral iron supplementation in these patients requires caution.
Objet agglutiné et trace mnésique non représentée
Authors: Chocron Michael , Capart Noémie , de Matteis Vanessa 
Published: July 2018

Les travaux théoriques sur la clinique de l’autisme insistent beaucoup sur les aspects archaïques des mouvements psychiques à l’œuvre chez ces sujets. Cependant, la théorisation de l’archaïque va bien au-delà de la clinique de l’autisme. Cet article cherche à proposer une lecture plus transversale des difficultés des sujets autistes, en s’appuyant sur des concepts psychanalytiques hors du champ immédiat de l’autisme. Dans cette perspective, les auteurs s’appuieront, en premier lieu, sur la notion d’objet agglutiné de J. Bleger, tiré d’une clinique avec des patients psychotiques. En second lieu, les auteurs exploreront le concept de trace mnésique sensitivo-perceptivo-motrice de R. Roussillon, issu d’une clinique avec des patients psychotiques et états-limites. La liaison de ces deux concepts permet d’envisager comment des traces mnésiques non subjectivées, présentes chez le sujet autiste, peuvent être stabilisées par un objet agglutiné afin de limiter l’effet déstabilisant pour le psychisme de ces traces profondément inconscientes. Les auteurs s’appuieront sur l’exposé d’un cas issu de la clinique d’un d’entre eux. Cet extrait du début de la thérapie d’un adolescent présentant des troubles autistiques permettra d’illustrer la construction théorique envisagée. Enfin les auteurs envisageront les aspects spécifiques que le fonctionnement psychique d’un sujet autiste imprime à cette théorisation avant d’ouvrir sur la question de ce que les fonctionnements autistiques permettent d’appréhender des processus psychiques archaïques.
Un pour tous : essai sur l’utilité publique des régents d’école (Champagne, vers 1650 – vers 1770)
Authors: Bisaro Xavier 
Published: July 2018

Considérant à nouveaux frais le maillage scolaire serré de la Champagne sous l’Ancien Régime, cet article met au jour le faisceau de relations existant entre les prescripteurs des obligations du maître d’école de village (évêque, curé, marguillier, intendant), les « usagers » de ses fonctions (prêtres, laïcs adultes et enfants) et le maître lui-même, et ce en insistant plus particulièrement sur ses devoirs liturgiques au service de la paroisse. Partant de la définition théorique du rôle du régent par les autorités religieuses, l’étude aborde ensuite son activité à l’église tels que les archives permettent de la reconstituer, puis les concertations ou les négociations que son implantation locale pouvait déclencher. De la sorte, le maître d’école de la fin du XVIII e siècle se laisse voir sous l’apparence de ses « deux corps » – celui de l’instituteur des enfants et celui de l’initiateur du village – soumis à des idéaux complémentaires mais à des formes d’action, à des conventions et à des niveaux de pouvoir séparés.
Imaginaire de la online religion
Authors: Berzano Luigi , La Rocca Fabio 
Published: July 2018

La religion sur Internet possède une liaison particulière avec la production des imaginaires. Cet article présente une typologie d’imaginaires de la online religion à partir d’une recherche réalisée sur les comportements d’une page Facebook en Italie dans les années 2015-2016 : immaginario peer to peer, immaginario delle identità multiple, immaginario del feeling of belonging, immaginario emozionale, immaginario solidale, immaginario autopoietico.
The impact of financial support on the success of small, medium and micro enterprises in the Eastern Cape province
Authors: Rungani Ellen C. , Potgieter Marius 
Published: July 2018

Orientation: In developing economies, the growth of the economy could be fostered and enhanced by the expansion of the private sector, as this sector is the engine of economic growth. Consequently, it is necessary to accelerate the success of small, medium and micro enterprises (SMMEs) to achieve sustainability in this sector of the economy.Research purpose: The main aim of this article was to determine the relevance of financial support offered to SMMEs by both private and public sectors on the success of businesses.Motivation for the study: The impact of finance on SMME performance is well documented from an international perspective. However, what lacks in extant literature is the understanding of whether the financial support being offered by both public and private sectors is relevant to the success of businesses.Research design, approach and method: A post-positivist paradigm was used with a quantitative research design, which made use of self-administered questionnaires to assess the relevance of financial support offered to SMMEs by both private and public sectors. Multiple regressions and correlations were computed to test the research hypotheses.Main findings: The findings suggest that SMME success is positively and significantly correlated with financial support for both private and public sectors.Practical/managerial implications: Although financial support is important, it needs to be restructured so as to incorporate practical aspects. Furthermore, private and public sectors should create an enabling environment that encourages the effective use of finances, which, in turn, will improve the success of businesses.Contribution/value-add: This article is of particular value to policymakers for ways to improve the success of SMMEs.
Those Who Teach, Can Do: Characterizing the Relationship Between Teaching and Clinical Skills in a Residency Program
Authors: Smith C. Christopher , Newman Lori R. , Huang Grace C. 
Published: July 2018

ABSTRACT

Background
Teaching practice is presumed to have significant overlap with clinical skills, yet few studies to date have assessed how residents' teaching skills influence their clinical performance.

Objective
We examined the relationship between the professional roles of residents as teachers and as practicing clinicians as well as how learning about teaching contributes to enhanced skills in the clinical realm.

Methods
Using the framework method, the authors performed a 2-phased (exploratory and confirmatory) qualitative analysis on the data sets to characterize the relationship between resident teaching and clinical skills. To investigate the relationship between teaching and clinical work, we extracted qualitative data from 300 evaluations of clinical performance for residents in a large, urban, academic internal medicine residency program submitted over a 3-year period. Informed by the preliminary framework that evolved from this analysis, we conducted a focus group of 6 residents in a dedicated clinician-educator track to examine how teaching was related to clinical work.

Results
We identified attributes and skills of good resident teachers that enhance clinical skills, categorized as 18 subdomains within 4 domains: relationships, communication, relation to self, and relationship with knowledge.

Conclusions
Themes that link clinical and teaching skills are similar for both patient-physician and learner-teacher relationships. Improving residents' teaching skills may not only benefit the education of learners but also improve the care of patients.
A Prospective Evaluation of a Modified Belt-Loop Gastropexy in 100 Dogs with Gastric Dilatation-Volvulus
Authors: Formaggini Luca , Degna Matteo Tommasini 
Published: July 2018

ABSTRACTGastropexy is a surgical technique performed to prevent and decrease the recurrence rate of gastric dilatation and volvulus (GDV). The objective of this prospective, a descriptive cohort study on 100 client-owned dogs who were presented with GDV, is to describe a modified belt-loop gastropexy and determine its intraoperative complications and long-term efficacy.The transversus abdominis muscle was used to make an oblique belt-loop. A seromuscular antral fold, instead of a seromuscular antral flap, was passed through the belt-loop, and then, the passed portion of the antral fold was sutured to the dissected edge of the abdominal wall. Intraoperative complications related to gastropexy were recorded, and the incidence of GDV recurrence was determined a minimum of 1 yr postoperatively via telephone with the referring veterinarians and the owners. There were no intraoperative complications related to the modified belt-loop gastropexy technique. Based on follow-up conversations, none of the dogs presented signs of GDV recurrence during the follow-up period. Based on the results, there is strong clinical evidence that a modified belt-loop gastropexy prevents recurrence of GDV in dogs surviving an acute episode.
Approaches to Canine Heartworm Disease Treatment Among Alumni of a Single College of Veterinary Medicine
Authors: Dixon-Jimenez Amy C. , Coleman Amanda E. , Rapoport Gregg S. , Creevy Kate E. , Roth Ira , Correa Maria , Moorhead Andrew R. 
Published: July 2018

ABSTRACTThis descriptive study was designed to ascertain the current heartworm treatment strategies employed by veterinary graduates of a single college of veterinary medicine, to assess the frequency with which each of these treatment strategies is prescribed, and to report the motivation behind the use of these treatment strategies. A survey containing a combination of multiple-choice and open-ended questions was distributed via e-mail with an online link during 2013 to graduates of the University of Georgia College of Veterinary Medicine. Demographic data and opinions regarding treatment for cases of canine heartworm disease (HWD) were obtained, and motivation for recommending different treatment strategies was assessed. Nearly all 170 respondents (99%) indicated that they recommend melarsomine dihydrochloride for first-line treatment of canine HWD. Exercise restriction (80%) and monthly heartworm preventive (75%) were components of the treatment approach to HWD with no clinical signs. The majority of respondents (74%) indicated that when first-line treatment recommendations were declined, they endorsed long-term administration of ivermectin (i.e., “slow-kill” method) despite current American Heartworm Society guidelines that recommend against the use of long-term macrocyclic lactone administration for the monotherapy treatment of canine HWD. Respondents also indicated that owners’ financial concerns frequently result in modification of HWD treatment. Routine inclusion of exercise restriction is commonly, but not universally, utilized and may represent an opportunity for improvement in the management of this disease. In addition, when first-line recommendations for heartworm disease treatment are declined, a two-dose melarsomine protocol instead of the slow-kill method should be considered.
Pericardial Hemangiosarcoma in a 10-Year-Old Papillon
Authors: DeSandre-Robinson Dana M. , Quina Mariana T. , Lurie David M. 
Published: July 2018

ABSTRACTA 10 yr old papillon was evaluated for lethargy, inappetence, tachypnea, and labored breathing. Physical examination findings included dehydration, tachypnea, tachycardia, and muffled heart sounds. Thoracic radiographs revealed an enlarged cardiac silhouette. Echocardiography revealed a mild volume of pericardial effusion and no evidence of right atrial tamponade or a cardiac-associated mass. Cytological analysis of the pericardial effusion was consistent with blood. There was no evidence of neoplasia. Coagulation parameters were within normal limits. Initial treatment consisted of pericardiocentesis. A subtotal pericardiectomy was later performed. No surgical complications were noted, and the dog was discharged 2 days following surgery. Results of the histological examination of the pericardium revealed hemangiosarcoma. Treatment with doxorubicin was initiated 12 days after surgery, at which time, pulmonary metastasis was suspected. The dog survived for 18 days after subtotal pericardiectomy, when it was euthanized because of complications presumably related to pulmonary metastatic disease. This is the first published report of primary pericardial hemangiosarcoma. The dog had a short survival time; thus, the response to subtotal pericardiectomy combined with adjuvant doxorubicin treatment could not be determined. Pulmonary metastatic disease was suspected 12 days following surgery. Based on this case report, pericardial hemangiosarcoma carries a guarded prognosis.
Intramural Abscess Causing Obstruction at a Previous Jejunal Enterotomy Site in a Dog
Authors: Smeak Daniel Dwight , Turner Hannah , Hoon-Hanks Laura 
Published: July 2018

ABSTRACTThis case report documents a novel late surgical complication in a 2 yr old dog following an enterotomy to remove a jejunal foreign body. Twenty-six days following the original surgery, the dog was re-presented with signs consistent with an intestinal obstruction. A mural intestinal abscess was found as the cause of the obstruction during exploratory surgery, and the site was successfully removed with a resection and anastomosis. Histopathology showed multifocal abscessation with cyst-like structures partially lined with mucosa. The dog recovered without complication and remains healthy 4 mo later. The exact cause of the lesion is not known; however, local contamination through a focal mucosal defect or complications related to the use of barbed suture in the original enterotomy repair may have contributed.
Editorial
Authors: Carballo Palma Anielka Patricia 
Published: July 2018

La Revista Universidad y Ciencia presenta en este número una contribución al sector ganadero con la propuesta del efecto sobre la producción y calidad de la leche al usar harina de guácimo y guanacaste. También se pueden leer dos artículos de salud, los cuales realizan estudios de caso, uno referido a los riesgos evisceración en pacientes sometidos a laparotomía y el segundo sobre toxoplasmosis ocular.
Efecto sobre la producción y calidad de leche de la suplementación con harina de guácimo y Guanacaste
Authors: Laguna Gámez Julio Cesar , Ordóñez Rodríguez Margarita 
Published: July 2018

El experimento se realizó en la finca San Ramón, propiedad del señor Leonardo Castro, comunidad La Lima, San Ramón, Matagalpa. Se empleó un diseño Balanced Complete Block Crossover Design, compuesto de dos tratamientos y un testigo. El primer tratamiento consistió en someter tres vacas de raza Jersey de 360 kg a consumir la alimentación habitual que el productor les proporciona que consiste en Pasto Taiwán (Pennisetum purpureum) este fue el testigo. El segundo tratamiento 2 kg de harina de guácimo (Guazuma ulmifolia). El tercer tratamiento 2 kg de harina de guanacaste (Enterolobium cyclocarpum). Cada tratamiento con tres periodos y los periodos fueron las repeticiones, cada unidad experimental constituida por una vaca en lactación. Cada tratamiento tuvo una duración de 12 días, con tres días de adaptación, seis días de evaluación y tres días de descanso, para una duración total de 36 días. Las variables en estudio fueron la producción de leche y la calidad de la leche. Se realizaron ANDEVA para cada variable y Prueba de rangos múltiple de Duncan. Se determinó que harina de frutos de guanacaste contiene un nivel proteico de 20.42 % y harina de guácimo un 8.81 % mediante análisis bromatológico. La suplementación con harina de guácimo incrementa la producción de leche hasta un 15.58% con respecto a la suplementación testigo. Se demuestra que la harina de guanacaste mejora la calidad de la leche en materia grasa y sólidos totales
Imposto de renda da pessoa física e pessoalidade: uma relação precária e em deterioração
Authors: Canuto Coelho André Felipe , Borba Bruna Estima 
Published: July 2018

O presente artigo compõe uma série de estudos que investiga o grau de concretização do princípio da capacidade econômica no que se refere ao imposto de renda das pessoas físicas (IRPF). Neste artigo, em especial, é pesquisada a natureza pessoal deste imposto. Utilizando o método indutivo e por meio da revisão doutrinária, normativa e jurisprudencial, as características deste imposto são analisadas. Mediante o exame de dados disponibilizados pela Secretaria da Receita Federal, abrangendo o período de 2001 a 2014 e relativos aos grandes números dos rendimentos e deduções declarados, pretende-se demonstrar a precariedade da pessoalidade do IRPF e sua deterioração ao longo do período analisado.
Classification tree for the prediction of malignant disease and the prediction of non-diagnostic biopsies in patients with small renal masses
Authors: Organ Michael , MacDonald Landan P. , Jewett Michael A.S. , Ajzenberg Henry , Almatar Ashraf , Abdolell Mohamed , Acker Matthew R. , Rendon Ricardo 
Published: July 2018

Introduction: Preoperative prediction of benign vs. malignant small renal masses (SRMs) remains a challenge. This study: 1) validates our previously published classification tree (CT) with an external cohort; 2) creates a new CT with the combined cohort; and 3) evaluates the RENAL and PADUA scoring systems for prediction of malignancy.
Methods: This study includes a total of 818 patients with renal masses; 395 underwent surgical resection and 423 underwent biopsy. A CT to predict benign disease was developed using patient and tumour characteristics from the 709 eligible participants. Our CT is based on four parameters: tumour volume, symptoms, gender, and symptomatology. CART modelling was also used to determine if RENAL and PADUA scoring could predict malignancy.
Results: When externally validated with the surgical cohort, the predictive accuracy of the old CT dropped. However, by combining the cohorts and creating a new CT, the predictive accuracy increased from 74% to 87% (95% confidence interval 0.84–0.89). RENAL and PADUA score alone were not predictive of malignancy. One limitation was the lack of available histological data from the biopsy series.
Conclusions: The validated old CT and new combined-cohort CT have a predictive value greater than currently published nomograms and single-biopsy cohorts. Overall, RENAL and PADUA scores were not able to predict malignancy.
Risico’s rondom de eindovereenkomst bij mediation in strafzaken
Authors: Dierx Janny , Panis Marlène 
Published: July 2018

Exploring the risks surrounding final party-agreements in penal mediations – About juridification, conflicts of interests and the need to manage expectations
Penal mediation is currently gaining ground within the Dutch criminal law system. The practice of penal mediation is still young, however, and therefore vulnerable. Common criminal practice as well as legislation are not yet thoroughly compatible with practicing penal mediation. The authors of this contribution explore some of the dangers mediators in penal cases face while drafting party-agreements that are to be taken into consideration by the judicial authorities.The article identifies the responsibilities of penal mediators who at the same time serve the interests of victims and offenders as well as take into account expectations judicial authorities might have. The responsibility of penal mediators is especially delicate whenever mediation parties seek to influence the outcome of the criminal lawsuit through mediation. Criminal law is a highly-regulated field, which – albeit unconsciously – seduces the mediator his- or herself to lose track of the main restorative goals of the mediation process. The authors point out some of the traps penal mediators can and should avoid. The article for instance elaborates the inadequacy of current Dutch regulations to arrange financial compensations and damages through penal mediation. Also, the article enumerates examples of over-juridification as well as the lacking of it. Furthermore, avoidable pitfalls such as McDonald-icing of penal mediation, the uselessness of so-called sunny-weather-vouchers, the dangers of copy-paste-agreements and – the worst – putting the height of their own – currently fixed – fees above party interests, are being addressed.
Morphometric Study of Pulmonary Arterial Changes in Pulmonary Langerhans Cell Histiocytosis
Authors: Bois Melanie C. , May Adam M. , Vassallo Robert , Jenkins Sarah M. , Yi Eunhee S. , Roden Anja C. 
Published: July 2018

Context.—
Pulmonary hypertension (PHT) is a complication of pulmonary Langerhans cell histiocytosis (PLCH); however, the pathogenesis remains largely unknown. Few studies have evaluated histopathologic changes in pulmonary arteries (PAs) of patients with PLCH; systematic quantification of arterial remodeling has yet to be undertaken.

Objective.—
To quantify the extent of arterial remodeling among patients with PLCH through morphometry and to correlate these results with pertinent clinical parameters.

Design.—
Patients with PLCH were identified from institutional files (1995–2015) along with age-, sex-, and smoking status–matched controls. Morphometric analysis of intimal and medial thickness of small to medium PAs was performed in patients with PLCH (within PLCH lesions [lesional] and away from PLCH lesions [nonlesional]) and controls. Paired measures were compared with Wilcoxon signed rank tests.

Results.—
Twenty-five patients with PLCH (14 men: median age, 46 years; interquartile range, 37–55 years) and 25 controls were included. The lesional arteries of patients with PLCH demonstrated thicker PA intima and media than controls (P &lt; .001 and P &lt; .001, respectively), as did PLCH nonlesional arteries compared to controls (P &lt; .001 and P &lt; .001, respectively). The PA intima and media were thicker within the PLCH lesions than nonlesional arteries (P = .02 and P = .002, respectively). Patients with PLCH-related PHT had a worse prognosis than those without PHT (P = .04; hazard ratio, 4.5 [1.1, 22.2]). Echocardiography parameters including right atrial size (P = .007), estimated right atrial pressure (P = .01), and right ventricular systolic pressure (P = .01) were inversely associated with survival.

Conclusions.—
Our findings suggest that factors other than direct vascular obstruction or inflammatory cell infiltration contribute, at least in part, to the vascular remodeling in PLCH.