bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of speed and heel-to-toe drop in running shoes for female recreational runners
Authors: Gijon-Nogueron Gabriel , Soler-Crespo Francisco Jose , Sanchez-Rodriguez Raquel , Cabello-Marique David , Lopezosa-Reca Eva , Ortega-Avila Ana Belen 
Published: May 2019

Abstract
In recent years, the popularity of running has boomed and the number of women runners has risen sharply. However, little research has been conducted into the running cycle as concerns female runners. The aim of this study is to analyse, in women runners, the relationships between spatiotemporal parameters in the running cycle, the heel drop in running shoes and a progressive increase in training speed, when running on a treadmill.
Thirty-eight female runners were recruited from the Malaga University Athletics Club and Nerja Athletics Club. All were at least 18 years old, recreationally active (3–4 running sessions per week) and able to run 5 km in less than 25 min. Their running performance on a treadmill was recorded and spatiotemporal parameters assessed using the OptoGait system.
As the running speed increased (8–12–15 km/h) the spatiotemporal parameters of the running cycle altered: the flight time increased (P < .001) and the contact time decreased (P = .05). Heel drop (4–12 mm) was not significantly associated with any of the parameters (phase 1: P = .198; phase 2: P = .191; phase 3: P = .242).
A progressive increase in training speed on a treadmill directly influences the spatiotemporal parameters of the running cycle in women runners.
Chemotherapy-induced posterior reversible encephalopathy syndrome
Authors: Cacho-Díaz Bernardo , Lorenzana-Mendoza Nydia A. , Salmerón-Moreno Karen , Reyes-Soto Gervith , Castillo-Rangel Carlos , Corona-Cedillo Roberto , Escobar-Ceballos Salvador , Garza-Salazar Jaime G. de la 
Published: May 2019

Abstract

Rationale:
Posterior reversible encephalopathy syndrome (PRES) has been associated with the use of several medications, including chemotherapeutic agents.

Patient concerns:
A 65-year-old woman was diagnosed with adenocarcinoma of the ovary, after sixth-line treatment with topotecan, at the beginning of the fourth cycle, she was admitted to the emergency room for presenting tonic-clonic seizures, visual disturbance, and hypertension. A 66-year-old woman was diagnosed with bilateral breast cancer; due to disease progression, treatment with paclitaxel and gemcitabine was started, 1 month after the last dose of chemotherapy, she was admitted to the emergency room for suffering severe headache, altered mental status, tonic-clonic seizures, and hypertension. A 60-year-old patient diagnosed with breast cancer on the left side, underwent second-line chemotherapy with gemcitabine, carboplatin, and bevacizumab, and 1 month after the last dose of chemotherapy, she was also admitted to the emergency room due to altered mental status, vomiting, tonic-clonic seizures, and hypertension.

Diagnosis:
They were diagnosed as PRES based on physical examination, laboratory findings, and imaging techniques that revealed diffuse lesions and edema within the parieto-occipital regions.

Interventions:
They received support treatment with blood pressure (BP) control, seizures were controlled with a single anti-epileptic agent, and chemotherapeutic agents from the onset of PRES to its resolution were discontinued.

Outcomes:
All these patients improved after medical treatment was started.

Lessons:
Medical personnel and therapeutic establishments need to be made aware about this chemotherapy-induced neurologic complication.
An Empirical Investigation of Alleged Mediumistic Writing
Authors: Paraná Denise , Rocha Alexandre Caroli , Freire Elizabeth Schmitt , Lotufo Neto Francisco , Moreira-Almeida Alexander 
Published: May 2019

Abstract
The scientific study of mediumship can contribute to the understanding of the mind-brain relationship. This study investigated a letter written by the influential Brazilian “medium” Chico Xavier, whose authorship was attributed to a deceased person. We identified the letter's pieces of information that were objectively verifiable, and we analyzed their accuracy based on documents and on interviews with the deceased's relatives, and the likelihood of Xavier's access to the information via ordinary means. All the 29 items of verifiable information conveyed on the letter were rated as “clear and precise fit.” The information conveyed was highly specific (e.g., names, dates, and specific events). Fourteen items (48.3%) conveyed information that was also very private. We concluded that ordinary explanations for accuracy of the information (i.e., fraud, chance, information leakage, and cold reading) were highly unlikely. We recommend further research on the phenomenon of mediumistic writing, particularly experimental controlled studies with exceptionally gifted mediums.
Facilitators and Barriers to Participating in a Randomized Controlled Trial of a Psychological Therapy for Substance Use
Authors: Thong Ivan Shin Kai , Ulph Fiona , Barrowclough Christine , Gregg Lynsey 
Published: May 2019

Abstract
Research involving substance users with psychosis has high refusal and attrition rates. Understanding participants' experiences of research participation is therefore important. Twenty-two cannabis users with schizophrenia spectrum disorders were recruited. They were involved in a randomized controlled trial exploring the effectiveness of motivational interviewing plus cognitive behavioral therapy. Semistructured interviews were conducted, and their responses were analyzed using thematic analysis. Thematic analysis identified facilitators such as therapeutic benefit, knowledge about medical conditions, awareness of own drug habits, helping others, confidentiality, rapport with researchers, desiring social contact, and views of significant others. Barriers identified were cognitive challenge, amount of assessments, duration, and discussions about the past. Based on these insights, we recommend informing participants about clinical equipoise, confidentiality, and demands of the study; minimizing demands on participants; acknowledging participants' efforts; involving potential participants' significant others during recruitment; advertising research as an opportunity to help; and training researchers in building rapport.
Barriers and Facilitators to Implementing a Short-Term Transdiagnostic Mental Health Treatment for Homeless Persons
Authors: Youn Soo Jeong , Sauer-Zavala Shannon , Patrick Kaylie A. , Ahles Emily M. , Aguilar Silvan Yesenia , Greig Astrea , Marques Luana , Shtasel Derri L. 
Published: May 2019

Abstract
Despite the significant mental health needs and comorbidity in homeless individuals, there is a “science-practice gap” between the available evidence-based treatments (EBTs) and their lack of use in community health centers servicing homeless populations. To address this gap, it is imperative to evaluate and attend to the contextual factors that influence the implementation process of EBTs before their integration into routine care. The study aims to evaluate the barriers and facilitators to implementing a transdiagnostic EBT in a community health center serving homeless individuals. The results of the thematic analyses (7 focus groups, 67 participants) yielded 8 themes for barriers and 10 themes for facilitators to implementation. The findings of the current study highlight common tensions faced by community programs and clinicians when working toward integrating EBTs across different types of populations, and those unique to homeless persons. Results can inform subsequent strategies used in implementing EBTs.
Effect of a New Model-Based Reconstruction Algorithm for Evaluating Early Peripheral Lung Cancer With Submillisievert Chest Computed Tomography
Authors: Yongjun Jia , Bingying Zhai , Taiping He , Yong Yu , Nan Yu , Haifeng Duan , Chuangbo Yang , Xirong Zhang 
Published: May 2019

Objective
The aim of this study was to compare a new model-based iterative reconstruction algorithm with either spatial and density resolution balance (MBIRSTND) or spatial resolution preference (MBIRRP20) with the adaptive statistical iterative reconstruction (ASIR) in evaluating early small peripheral lung cancer (SPLC) with submillisievert chest computed tomography (CT).

Methods
Low-contrast and spatial resolutions were assessed in a phantom and with 30 pathologically confirmed SPLC patients. Images were reconstructed using 40% ASIR, MBIRSTND, and MBIRRP20. Computed tomography value and image noise were measured by placing the regions of interest on back muscle and subcutaneous fat at 3 levels. Two radiologists used a 4-point scale (1, worst, and 4, best) to rate subjective image quality in 3 aspects: image noise, nodule imaging signs, and nodule internal clarity.

Results
The phantom study revealed an improved detectability of low-contrast targets and small objects for MBIRSTND and MBIRRP20 compared with ASIR. The effective dose for patient scans was 0.88 ± 0.83 mSv. There was no significant difference in CT value between the 3 reconstructions (P > 0.05), but MBIRSTND and MBIRRP20 significantly reduced image noise compared with ASIR (P < 0.05): 15.69 ± 1.83 HU and 29.97 ± 3.84 HU versus 51.06 ± 11.02 HU in the back muscle, and 15.96 ± 3.07 HU and 27.37 ± 3.88 HU versus 38.04 ± 8.87 HU in subcutaneous fat, respectively. Among the 3 reconstructions, MBIRSTND was the best in reducing image noise and identifying the internal compositions of cancer nodules, and MBIRRP20 was the best in analyzing the internal and external signs of pulmonary nodules.

Conclusions
Submillisievert chest CT reconstructed with MBIRSTND and MBIRRP20 provides superior images for the detailed analyses of SPLC compared with ASIR.
Cardiovascular Magnetic Resonance Provides Evidence of Abnormal Myocardial Strain and Primary Cardiomyopathy in Marfan syndrome
Authors: Winther Simon , Williams Lynne K. , Keir Michelle , Connelly Kim A. , Bradley Timothy J. , Rakowski Harry , Crean Andrew M. 
Published: May 2019

Objective
Marfan syndrome is an autosomal-dominant genetic disorder caused by mutations in the fibrillin-1 gene. The condition is a connective tissue disease that frequently involves the cardiovascular system. The existence of a primary cardiomyopathy in Marfan syndrome, however, is controversial. The aims of this study were to investigate the prevalence of left ventricular dysfunction with both transthoracic echocardiography and cardiovascular magnetic resonance (CMR) in a cohort of Marfan syndrome patients and to investigate patterns of myocardial strain across the cohort.

Methods
We used an institutional database to identify all patients with a firm diagnosis of Marfan syndrome based on Ghent criteria. Inclusion required left ventricular ejection fraction (LVEF) to have been measured by both CMR and transthoracic echocardiography within 12 months of each other. Normal LVEF was defined as a value of >55% when measured by CMR. Velocity vector imaging was used to measure left ventricular longitudinal strain patterns by application of feature tracking to cine magnetic resonance images. Results were compared with data from 20 age-matched control subjects.

Results
Sixty-nine Marfan syndrome patients met the inclusion criteria. The mean age was 35.4 ± 15.0 years, and 56.5% were male. The mean LVEF was 59.0% ± 7.0% by CMR and 59.1% ± 5.8% by echo. One-fifth of Marfan syndrome patients (15/69; 21.7%) had reduced function with LVEF ≤55% by CMR, but only 5 of these were identified by echo. Furthermore, echo identified 5 Marfan syndrome patients as having reduced LVEF in the presence of a normal LVEF by CMR. Some Marfan syndrome patients had abnormal longitudinal strain patterns even with LVEF within the reference range.

Conclusions
These data provide support for a primary cardiomyopathy in some Marfan syndrome patients. Cardiovascular magnetic resonance is more sensitive than echo for identifying cases with mild systolic dysfunction. Strain analysis may be more sensitive than simple LVEF assessment for identifying at-risk individuals.
Computed Tomography–Colonography With Intravenous Contrast Medium and Urographic Phase for the Evaluation of Pelvic Deep Infiltrating Endometriosis of Intestinal and Urinary Tract
Authors: Coppola Francesca , Paradisi Roberto , Zanardi Sara , Papadopoulos Dimitris , Gramenzi Annagiulia , Valerio Domenico , Pierotti Luisa , Zannoni Letizia , Seracchioli Renato , Golfieri Rita 
Published: May 2019

Objectives
The aim of this study was to evaluate the diagnostic accuracy of a specific protocol of computed tomography–colonography with intravenous contrast medium and urographic phase, which combined simultaneously the study of the intestinal and urinary tract, in the preoperative evaluation of women with deep infiltrating endometriosis (DIE) of anterior and posterior pelvic compartments.

Methods
We retrospectively analyzed 73 women who underwent 74 computed tomography–colonography with intravenous contrast medium and urographic phase examinations for strong clinical suspicion of DIE. All the women had surgical confirmation.

Results
Computed tomography–colonography with intravenous contrast medium and urographic phase in detecting DIE rectosigmoid involvement had a sensitivity of 82.3% and a specificity of 66.7%, while in detecting DIE urinary tract involvement had a sensitivity of 45.9% and a specificity of 78.4%.

Conclusions
Computed tomography–colonography with intravenous contrast medium and urographic phase is a useful technique for the preoperative planning of selected women with DIE, in particular, for the detection of sigmoid colon and bladder lesions especially when performed with a dose reduction protocol.
Contrast-Enhanced Ultrasonography in the Diagnosis of Portal Vein Thrombosis
Authors: Iliescu Laura , Toma Letitia , Mercan-Stanciu Adriana , Grumeza Mihaela , Ioanitescu Simona 
Published: May 2019

Abstract
Portal vein thrombosis is a frequently encountered complication in hepatology and hematology. In patients with liver cirrhosis, it can occur in the natural history of the disease due to clotting disorders or associated with hepatocellular carcinoma. The development of a malignant thrombus is a contraindication to several therapeutic procedures in liver cancer, such as liver resection or transplantation or transarterial chemoembolization; therefore, patients need to be attentively evaluated. Contrast-enhanced ultrasonography is a relatively new noninvasive imagistic investigation with proven accuracy in focal liver lesions. Its use in differentiating malignant and nonmalignant portal vein thrombosis is still controversial. This article revises the characteristics of portal vein thrombosis on contrast-enhanced ultrasonography in order to determine its accuracy in the diagnosis of malignant portal vein thrombosis.
Clinical Application of a Specific Simulation Software for 3-Dimensional Orbital Volume Modeling for Orbital Wall Reconstruction
Authors: Kim Min Ji , Jeong Woo Shik , Kim Yun Hwan , Kim Hannah , Cho Hyunchul , Kim Youngjun , Choi Jong-Woo 
Published: May 2019

Abstract
In this study, we developed a new 3-dimensional (3D) preoperative planning software and investigated its effectiveness by measuring orbital volume change. Fifty-six patients who underwent unilateral orbital wall reconstruction between December 2015 and February 2018 in our institute were recruited. We developed an orbit-specific automatic 3D modeling software (Osteopore CMF 3D) that can automatically detect orbital fracture site, process mirroring, measure volume, and then produce a customized orbital implant. Using preoperative and postoperative 3D computed tomography, orbital volume was measured and compared between Osteopore CMF 3D and the widely used Mimics. Intraclass correlation coefficient between Osteopore CMF 3D and Mimics showed 90.6% concordance for preoperative injured site orbital volume and 86.7% concordance for postoperative orbital volume, both being statistically significant (preoperative intraclass correlation coefficient, 0.906 [confidence interval {CI}, 0.840–0.945; P < 0.000]; postoperative intraclass correlation coefficient, 0.867 [CI, 0.773–0.922; P < 0.000]). For uninjured sites, the 2 software packages showed 76.6% preoperative concordance and 83.9% postoperative concordance, both being statistically significant (preoperative intraclass correlation coefficient, 0.766 [CI, 0.600–0.863; P < 0.000]; postoperative intraclass correlation coefficient, 0.839 [CI, 0.725–0.905; P < 0.000]). This study introduces our newly developed 3D surgical planning software specialized for orbital wall reconstruction and demonstrates its performance to be comparable with that of a widely used software.
Cytoreductive nephrectomy in metastatic kidney cancer: what do we do now?
Authors: Kokorovic Andrea , Rendon Ricardo A. 
Published: May 2019

Purpose of review
Metastatic renal cell carcinoma (mRCC) has traditionally been treated with a combination of targeted systemic therapy and cytoreductive nephrectomy. This approach has recently become a topic of debate, because of new randomized data suggesting a lack of survival benefit for cytoreductive nephrectomy. We review the literature relevant to cytoreductive nephrectomy in the modern era of targeted and immune systemic therapy, and discuss the ongoing role of surgery for treatment of patients with mRCC.

Recent findings
Randomized trials in the cytokine era of systemic therapy for mRCC demonstrated a survival benefit to cytoreductive nephrectomy, which led to its widespread adoption. There is overwhelming support in favor of cytoreductive nephrectomy from large studies using retrospective data in the targeted therapy era. A recent randomized control trial (CARMENA) failed to show superiority of cytoreductive nephrectomy in combination with sunitinib, versus sunitinib alone with respect to overall survival. The trial had major limitations including selection of many poor-risk patients, which we know do not benefit from surgery. The results of CARMENA should lead to the abandonment of cytoreductive nephrectomy in poor-risk and many intermediate-risk patients with mRCC. However, there is a knowledge gap with respect to the role of cytoreductive nephrectomy in patients with good risk disease, and we argue that these patients should be strongly considered for cytoreductive nephrectomy.

Summary
Cytoreductive nephrectomy continues to play an important role in the multidisciplinary management of mRCC; however, diligent patient selection is crucial, as only patients with good risk features are likely to derive benefit from surgery.
Genetic diversity by ISSR of two endemic quillworts (Isoetes L.) species from Amazon Iron Rocky Outcrops, Isoetes cangae e I. serracarajensis
Authors: Santos Mirella Pupo , da Silva Rabelo Araújo João Victor , Vinícius de Sant’anna Lopes Arthur , Vettorazzi Julio Cesar Fiorio , da Fonseca Rodrigo Nunes , Calderón Emiliano Nicolas , Boechat Marcela Santana Bastos , Arêdes Fernanda Abreu Santana , Pereira Messias Gonzaga , Campos Naiara Viana , Santos Fernando Marino Gomes dos , Fernandes Taís Nogueira , Martins Rodrigo Lemes , de Assis Esteves Francisco 
Published: May 2019

AbstractTwo lycophytes endemic species have been recently described at the State of Pará, in the Amazon forest located in the North of Brazil. Genetic diversity and population structure of Isoetes cangae and I. serracarajensis were investigated through ISSR molecular markers. These analyses aim to establish strategies for future attempts for species conservation. From sixteen primers, 115 gel bands were identified from which 87% were polymorphic. A high level of polymorphic loci (81,74 % e 68,48 %) and a high Shannon index for intra populational genetic diversity was observed for each species (Sh=0.376 e 0.289) I. cangae and I. serracarajensis, respectively. The largest genetic diversity of both species relies in their own populations. The coefficient of genetic differentiation between population areas (GST) was higher in I. serracarajensis (0.5440) than in I. cangae (0.2250). Gene flow was high between I. cangae populations (1.7142) and very low in I. serracarajensis (0.4190). Principal Component Analysis (PCoA) showed that individual plants were allocated into species-specific and population groups. Overall, the results further show that I. serracarajensis (0.5440) and I. cangae are two species with considerable genetic variation. These results should be considered for effective conservation strategies of both species.
Determination of heat transfer coefficient in a T-shaped cavity by means of solving the inverse heat conduction problem
Authors: Frąckowiak Andrzej , Spura David , Gampe Uwe , Ciałkowski Michał 
Published: May 2019

Purpose
T-shaped cavities occur by design in many technical applications. An example of such a stator cavity is the side space between the guide vane carriers and the outer casing of a steam turbine. Thermal conditions inside it have a significant impact on the deformation of the turbine casing. In order to improve its prediction, the purpose of this paper is to provide a methodology to gain better knowledge of the local heat transfer at the cavity boundaries based on experimental results.

Design/methodology/approach
To determine the heat transfer coefficient distribution inside a model cavity with the help of a scaled generic test rig, an inverse heat conduction problem is posed and a method for solving such type of problems in the form of linear combinations of Trefftz functions is presented.

Findings
The results of the calculations are compared with another inverse method using first-order gradient optimization technique as well as with estimated values obtained with an analytic two-dimensional thermal network model, and they show an excellent agreement. The calculation procedure is proved to be numerically stable for different degrees of complexity of the sought boundary conditions.

Originality/value
This paper provides a universal and robust methodology for the fast direct determination of an arbitrary distribution of heat transfer coefficients based on material temperature measurements spread over the confining wall.
Do culture and governance structure influence extent of corporate risk disclosure?
Authors: Agyei-Mensah Ben Kwame , Buertey Samuel 
Published: May 2019

Purpose
The purpose of this paper is to study the relationship between culture, corporate governance (CG) variables and corporate risk reporting practices of listed companies in Nigeria and South Africa, two large African economies at the south of the Sahara.

Design/methodology/approach
The study uses 500 firm-year observations for the period of 2013–2017 for firms listed on the Lagos and Johannesburg Stock Exchanges. Descriptive analysis was performed to provide the background statistics of the variables examined. This was followed by regression analysis, which constitutes the main data analysis.

Findings
The results indicate that power distance is negatively associated with the corporate risk disclosure (CRD). This implies that organizations where power distance is high are characterized by lower CRD and vice versa. From the analysis, two factors, namely, institutional ownership and profitability, were found to explain sample firms’ risk disclosure practices as they are positively and statistically related to CRD.

Originality/value
This study is one of the few to measure the influence of culture and CG on CRD in Sub-Sahara Africa. Understanding the drivers for firms to disclose risk-related information may assist regulators and standards setters in promoting both the spread and the improvement of such disclosures through the issuance of CG codes and reporting guidelines.