bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determination of Moisture Content and Basic Density of Poplar Wood Chips under Various Moisture Conditions by Near-Infrared Spectroscopy
Authors: Liang Long , Fang Guigan , Deng Yongjun , Xiong Zhixin , Wu Ting 
Published: May 2019

AbstractThe potential of near-infrared (NIR) spectroscopy coupled with partial least-squares (PLS) regression was used to determine the moisture content and basic density of poplar wood chips. NIR spectra collected from the surface of wood chips were used to develop calibration models for moisture content and basic density predication, and various spectral preprocessing techniques were applied to improve the accuracy and robustness of the prediction models. The models were tested using totally independent sample sets and exhibited acceptable predictive performance for moisture content (coefficient of determination for prediction [R2p] = 0.98 and standard error of prediction [SEP] = 2.51 percent) and basic density (R2p = 0.87 and SEP = 17.61 kg m–3). In addition, the effect of moisture variations on prediction of basic density was investigated based on NIR spectra from wood chips under various moisture levels. The results demonstrated that broad absorption bands from water molecules, especially when free water exists in the cell lumen, overlap with informative signals related to wood properties and weaken the calibration relation between spectral features and basic density. Thus, maintaining wood chips in a low and even moisture state would help achieve reliable estimates of wood density by NIR analysis models.
Rice Galaxy: an open resource for plant science
Authors: Juanillas Venice , Dereeper Alexis , Beaume Nicolas , Droc Gaetan , Dizon Joshua , Mendoza John Robert , Perdon Jon Peter , Mansueto Locedie , Triplett Lindsay , Lang Jillian , Zhou Gabriel , Ratharanjan Kunalan , Plale Beth , Haga Jason , Leach Jan E , Ruiz Manuel , Thomson Michael , Alexandrov Nickolai , Larmande Pierre , Kretzschmar Tobias , Mauleon Ramil P 
Published: May 2019

Abstract

Background
Rice molecular genetics, breeding, genetic diversity, and allied research (such as rice-pathogen interaction) have adopted sequencing technologies and high-density genotyping platforms for genome variation analysis and gene discovery. Germplasm collections representing rice diversity, improved varieties, and elite breeding materials are accessible through rice gene banks for use in research and breeding, with many having genome sequences and high-density genotype data available. Combining phenotypic and genotypic information on these accessions enables genome-wide association analysis, which is driving quantitative trait loci discovery and molecular marker development. Comparative sequence analyses across quantitative trait loci regions facilitate the discovery of novel alleles. Analyses involving DNA sequences and large genotyping matrices for thousands of samples, however, pose a challenge to non−computer savvy rice researchers.

Findings
The Rice Galaxy resource has shared datasets that include high-density genotypes from the 3,000 Rice Genomes project and sequences with corresponding annotations from 9 published rice genomes. The Rice Galaxy web server and deployment installer includes tools for designing single-nucleotide polymorphism assays, analyzing genome-wide association studies, population diversity, rice−bacterial pathogen diagnostics, and a suite of published genomic prediction methods. A prototype Rice Galaxy compliant to Open Access, Open Data, and Findable, Accessible, Interoperable, and Reproducible principles is also presented.

Conclusions
Rice Galaxy is a freely available resource that empowers the plant research community to perform state-of-the-art analyses and utilize publicly available big datasets for both fundamental and applied science.
Gender-Specific Acaricidal Properties and Sexual Transmission of Spirotetramat in Two-Spotted Spider Mite (Tetranychidae: Acariformes)
Authors: Popov Sergei Ya , Alyokhin Andrei 
Published: May 2019

Abstract
Two-spotted spider mite, Tetranychus urticae Koch (Tetranychidae: Acariformes), is one of the most important agricultural pests in the world. Their populations have a tendency of rapidly developing resistance to acaricides, making it necessary to have a variety of active ingredients for sustainable chemical control of this pest. We investigated acaricidal properties of a relatively new insecticide spirotetramat using its commercial formulation, Movento Energy. Spirotetramat applied at concentrations equivalent to the field rates of 78 and 90 g ai/ha had a strong negative effect on the survival of the treated T. urticae, with ca. 95% of females and ca. 65% of males dying after the treatment. Spirotetramat appeared to interfere with female reproductive system. Many of the dead treated females had eggs stuck in the oviduct and protruding from their bodies. Surviving treated females did not lay eggs. Furthermore, untreated females that mated with treated males did not produce female offspring and displayed the symptoms of spirotetramat poisoning. Toxic effects continued manifesting themselves after female mites were transferred from treated onto untreated plant culture. Contrary to previous studies, contact toxicity was also detected. None of the treated immature stages survived to adulthood. Based on these results, spirotetramat may be a good option for integrated pest management in crops that are simultaneously affected by sucking insects and spider mites and in pesticide rotation sequences that are a part of integrated resistance management programs.
Persistent Rivaroxaban Effect Due to Impaired Renal Clearance and Medication Effects
Authors: Milito Chelsea , McRae Hannah , Victor Adrienne , Refaai Majed A , Schmidt Amy E 
Published: May 2019

Abstract
Rivaroxaban (Xarelto; Johnson & Johnson Services, Inc) is a direct oral anticoagulant (DOAC) that works by directly inhibiting the active site of factor Xa (FXa). Rivaroxaban is metabolized and cleared via the kidney and liver. The results of various studies have shown that patients with severe renal impairment should receive reduced dosages of rivaroxaban or another anticoagulant due to impaired clearance. Although it is not required, monitoring rivaroxaban is useful in some conditions; however, the assays required for such monitoring are not readily available. Herein, we present a case of a 68-year-old Caucasian male patient who was receiving rivaroxaban (20 mg/day) for atrial flutter and had mild renal impairment. The patient was found to have increased effect of rivaroxaban due to further impairment of renal clearance caused by several renally cleared medications. This case highlights the importance of closely examining the renal function of and medication list for a patient before starting DOACs such as rivaroxaban.
Must I Accept Prosecution for Civil Disobedience?
Authors: Weltman Daniel 
Published: May 2019

Abstract
Piero Moraro argues that people who engage in civil disobedience do not have a pro tanto reason to accept punishment for breaking the law, although they do have a duty to undergo prosecution. This is because they have a duty to answer for their actions, and the state serves as an agent of the people by calling the lawbreaker to answer via prosecution. I argue that Moraro does not go far enough. Someone who engages in civil disobedience does not even have to show up for the trial, provided that they answer for their actions adequately via some other means. This is because sometimes states are not agents of the people who can call lawbreakers to account, and even those states which are agents cannot demand that lawbreakers answer for their crimes in the form of a trial.
A random matrix model with non-pairwise contracted indices
Authors: Lionni Luca , Sasakura Naoki 
Published: May 2019

Abstract
We consider a random matrix model with both pairwise and non-pairwise contracted indices. The partition function of the matrix model is similar to that appearing in some replicated systems with random tensor couplings, such as the $p$-spin spherical model for the spin glass. We analyze the model using Feynman diagrammatic expansions, and provide an exhaustive characterization of the graphs that dominate when the dimensions of the pairwise and (or) non-pairwise contracted indices are large. We apply this to investigate the properties of the wave function of a toy model closely related to a tensor model in the Hamilton formalism, which is studied in a quantum gravity context, and obtain a result in favor of the consistency of the quantum probabilistic interpretation of this tensor model.
ROUTINE METHOD FOR THE DETERMINATION OF TRACE AMOUNTS OF 226Ra IN URINE BY ALPHA SPECTROMETRY
Authors: Guérin Nicolas , McMullin Danielle , Fabian Xenia , Kramer-Tremblay Sheila , Gagné Alexandre , Gale Ashley 
Published: May 2019

Abstract
226Ra is considered one of the most radiotoxic naturally occurring radionuclides. A new routine method was developed to measure traces of 226Ra in urine. Radium was pre-concentrated from a 2 l urine sample using manganese oxide (MnO2) particles. The MnO2 precipitate was dissolved and the organic matter was broken down. Then, potential radiological interferents were removed using DGA and AGMP1 stacked resin columns. A barium sulphate (BaSO4) micro-precipitation was performed before measuring the sample by alpha spectrometry. A good recovery of 60 ± 10% and excellent alpha resolution were obtained. The minimum detectable activity (MDA) was 0.2 ± 0.1 mBql−1. The method was validated using spiked samples and can be completed in 5 hours.
Association between insomnia disorder and cognitive function in middle-aged and older adults: a cross-sectional analysis of the Canadian Longitudinal Study on Aging
Authors: Cross Nathan E , Carrier Julie , Postuma Ronald B , Gosselin Nadia , Kakinami Lisa , Thompson Cynthia , Chouchou Florian , Dang-Vu Thien Thanh 
Published: May 2019

AbstractObjectivesThis study examined the differences in cognitive function between middle-aged and older adults with insomnia disorder, insomnia symptoms only (ISO) or no insomnia symptoms (NIS), in the context of other health and lifestyle factors.MethodsTwenty-eight thousand four hundred eighty-five participants >45 years completed questionnaires, physical examinations, and neuropsychological testing across domains of processing speed, memory, and executive functions. An eight-question instrument assessed participants’ sleep, defining subjects with insomnia symptoms, probable insomnia disorder (PID), or NIS. The associations between these three groups and cognitive performance were examined with linear regression models adjusted for lifestyle and clinical factors.ResultsPID was identified in 1,068 participants (3.7% of the sample) while 7,813 (27.5%) experienced ISO. Participants with PID exhibited greater proportions of adverse medical and lifestyle features such as anxiety, depression, and diabetes than both other groups. Analyses adjusting for age, sex, education, as well as medical and lifestyle factors demonstrated that adults with PID exhibited declarative memory deficits (Rey Auditory Verbal Learning Test) compared with ISO or NIS. Adults with insomnia symptoms exhibited better performance on a task of mental flexibility than both other groups.ConclusionsThese findings suggest that insomnia disorder in middle-aged and older adults is associated with poorer health outcomes and worse memory performance than adults with insomnia symptoms alone or without any sleep complaints, even after adjustment for comorbidities. The assessment of longitudinal data within this cohort will be critical to understand if insomnia disorder may increase the risk of further cognitive decline.
Pharmacological Modulation of Sleep Homeostasis in Rat: Novel Effects of an mGluR2/3 Antagonist
Authors: Hanley Nicola , Paulissen Jerome , Eastwood Brian J , Gilmour Gary , Loomis Sally , Wafford Keith A , McCarthy Andrew 
Published: May 2019

Abstract
Increasing vigilance without incurring the negative consequences of extended wakefulness such as daytime sleepiness and cognitive impairment is a major challenge in treating many sleep disorders. The present work compares two closely related mGluR2/3 antagonists LY3020371 and LY341495 with two well-known wake-promoting compounds caffeine and d-amphetamine. Sleep homeostasis properties were explored in male Wistar rats by manipulating levels of wakefulness via (1) physiological sleep restriction (SR), (2) pharmacological action, or (3) a combination of these. A two-phase nonlinear mixed-effects model combining a quadratic and exponential function at an empirically estimated join point allowed the quantification of wake-promoting properties and any subsequent sleep rebound. A simple response latency task (SRLT) following SR assessed functional capacity of sleep-restricted animals treated with our test compounds. Caffeine and d-amphetamine increased wakefulness with a subsequent full recovery of non-rapid eye movement (NREM) and rapid eye movement (REM) sleep and were unable to fully reverse SR-induced impairments in SRLT. In contrast, LY3020371 increased wakefulness with no subsequent elevation of NREM sleep, delta power, delta energy, or sleep bout length and count, yet REM sleep recovered above baseline levels. Prior sleep pressure obtained using an SR protocol had no impact on the wake-promoting effect of LY3020371 and NREM sleep rebound remained blocked. Furthermore, LY341495 increased functional capacity across SRLT measures following SR. These results establish the critical role of glutamate in sleep homeostasis and support the existence of independent mechanisms for NREM and REM sleep homeostasis.
The Drafters’ Dance: The Complexity of Drafting Legislation and the Limitations of ‘Plain Language’ and ‘Good Law’ Initiatives
Authors: Webb Thomas E , Geyer Robert 
Published: May 2019

Abstract
Can we provide legislative drafters with tools to simplify and clarify legislation, and make it more accessible? In the United Kingdom, United States, Canada, Australia, and European Union, through strategies such as the ‘Plain Language’ and ‘Good Law’ (PL/GL) initiatives, it is claimed that the answer is ‘yes’. Though many of the normative intentions underlying such initiatives are commendable, we argue that the pursuit of legislative and legal simplicity, clarity, and accessibility ignores the distinctly ‘complicated’ and ‘complex’ role of legislation and legislative drafters. This leads to a range of contradictory and paradoxical outcomes that undermine these goals. Following a review of the role of legislative drafters and PL/GL initiatives, we use a complexity tool, the Stacey Diagram, to demonstrate and visualize the inherent tensions in the PL/GL position. We show how legislative drafters negotiate their complex environment in a much more subtle, human way than is commonly recognized in PL/GL discourse.
6Ecocriticism
Authors: Ryan John Charles 
Published: May 2019

AbstractThis review of publications in the field of ecocriticism in 2018 is divided into six sections: 1. Introduction: Anthropocene Timescales and Affects; 2. Affective Ecocriticism; 3. Material and Empirical Ecocriticisms; 4. Ecocriticism and Ecopoetics; 5. Ecocritical Convergences; 6. Conclusion. The review focuses on four single-authored monographs, three edited book collections, three journal issues, and three stand-alone articles. The biospheric urgencies of the Anthropocene and its cataclysmic signature—climate change—have attracted ecocritical attention to concerns of time, scale, and affect. In particular, 2018 marked the further maturation of material and queer ecocriticisms, the florescence of affective ecocriticism, and the germination of empirical ecocriticism. The field in 2018 explores, in depth, the role of affect—emotions, intensities, corporealities, and modes of relations—in the Anthropocene. All the while, confluences between affective, material, and queer ecocriticisms continue to broaden the scope of environmental affect to include ‘bad’ and irreverent modes. What’s more, new publications in material ecocriticism draw attention to environmental narratives as vehicles for concretizing the highly abstract spatiotemporalities of the Anthropocene whereas empirical ecocriticism applies qualitative methods to understanding the transformative potential of narratives. 2018 saw major studies of ecopoetics in addition to convergences between ecocriticism, animal studies, performance studies, crime fiction studies, and the environmental humanities. The year also brought the extension of ecocritical approaches to the genre of crime fiction and the literature of the Global South.
NP student encounters with obesity bias in clinical practice
Authors: Hauff Caitlyn , Fruh Sharon M. , Graves Rebecca J. , Sims Brook M. , Williams Susan G. , Minchew Leigh A. , Hall Heather R. , Platt Terrie H. , Barclay Mi'Asia 
Published: May 2019

Abstract:
This study explores NP students' encounters with obesity stigma and bias in their clinical environment as well as recommendations to decrease obesity stigma and bias. Results indicate a need for continued education on the topic of weight management within NP curricula.
Cytologic Grading of Cutaneous Sebaceous Neoplasms: Does it Help to Differentiate Benign From Malignant?
Authors: Tirado Mariantonieta , Metze Dieter , Sahlmann Jörg , Böer-Auer Almut 
Published: May 2019

Abstract:
Both architectural and cytologic characteristics are used to distinguish benign from malignant sebaceous neoplasms; however, specific cytopathologic features of sebocytes have not been well defined. The authors assessed architectural and cytological features of 63 sebaceous neoplasms [15 sebaceous hyperplasias, 12 sebaceomas, 16 sebaceous adenomas (SA), 14 sebaceous carcinomas (SC), and 6 ocular sebaceous carcinoma (OSC)] to investigate whether cytological grading may facilitate classification of lesions. Among other criteria, nuclear pleomorphism (size, nucleolar appearance, membrane irregularity, crowding, mitoses, and chromatin pattern) was assessed and 3 theoretical nuclear grades established. Immunohistochemistry for CK10, p16, adipophilin and ki67 was performed on 7 cases of each type of tumor. Most sebaceous neoplasms, except OSC, showed a bland architectural silhouette. However, SA, SC, and OSC revealed larger nuclei (≥14 μm in ≥50% of cases), evident to multiple nucleoli, membrane irregularity, coarse to clumped chromatin, and nuclear grade ≥2 (latter in ≥56% of cases); by contrast, sebaceous hyperplasia and sebaceomas showed smaller nuclei (≤10 μm in ≥50% of cases), smooth borders, inconspicuous nucleoli, fine chromatin, and grade 1 nuclei (latter in 100% of cases). In the setting of a well-circumscribed architecture, cytologic features gain importance in the classification of sebaceous neoplasms. Interestingly, cytologic similarities found in SA and SC may indicate a close relationship of both neoplasms.
Superficial Nodular Fasciitis With Atypical Presentations: Report of 3 Cases and Review of Recent Molecular Genetics
Authors: Maloney Nolan , LeBlanc Robert E. , Sriharan Aravindhan , Bridge Julia A. , Linos Konstantinos 
Published: May 2019

Abstract:
Nodular fasciitis is a benign proliferation of fibroblasts/myofibroblasts that can be mistaken for an aggressive neoplasm because of its spectrum of appearances and anatomical locations, rapid growth, infiltrative growth pattern, and high mitotic rate. The presence of fusions involving USP6 gene in most cases provides a useful tool for diagnostic confirmation. Nodular fasciitis is often deep, in association with fascia, but less commonly, it arises superficially and can be biopsied by dermatologists. We present herein 3 such cases with confirmed USP6 rearrangement by fluorescence in situ hybridization (FISH) in which the diagnosis of nodular fasciitis was not initially obvious because of atypical morphologic and clinical features. These cases illustrate that in cutaneous myofibroblastic proliferations, nodular fasciitis should be given consideration even when encountered in unusual locations.
Northwestern and Other Historical Vignettes regarding the Vascular Anastomotic Coupling Device
Authors: Dumanian Gregory A. , Janes Lindsay E. , Dumanian Zari P. 
Published: May 2019

Summary:
The vascular anastomotic coupling device is a widely used and effective aid to reconstructive microsurgery. Although there is a long history of innovators connected with this device, the current design of 6 interdigitating holes and pins was created de novo by a Northwestern medical student in 1960.
Current Trends in Management of Nonsyndromic Unilateral Coronal Craniosynostosis: A Cross-sectional Survey
Authors: Moderie Christophe , Govshievich Alexander , Papay Frank , Fearon Jeffrey , Gosain Arun , Doumit Gaby 
Published: May 2019

Background:
Although the natural history of nonsyndromic unilateral coronal craniosynostosis has been extensively described, optimal management remains controversial due to lack of Level 1 evidence. This study aims to assess the current state of practice among craniofacial surgeons.

Methods:
Ninety-four craniofacial surgeons were approached to complete a survey consisting of 15 questions. Data were collected assessing surgeons’ primary surgical indication, timing of intervention, preoperative imaging, and choice of technique for patients presenting with nonsyndromic unilateral coronal craniosynostosis. Choice of technique and timing of intervention in case of recurrence were also investigated.

Results:
After 5 mailings, the response rate was 61%. The combination of both appearance and raised intracranial pressure was the primary indication for treatment for 73.2% of surgeons. Preoperative CT scan of the skull was “always” performed by 70.1% of respondents. Open surgical management was most commonly performed at 8–10 months of age (38.6%). Bilateral frontal craniectomy with remodeling of the supraorbital bandeau and frontal bone was the most common choice of procedure (84.2%). In case of mild to moderate and moderate to severe recurrences at 1 year of age, 89.5% and 47.4% of surgeons opted for conservative management, respectively. Optimal timing for repeat cranioplasty was after 4 years of age (65.5%). Overall, 43.4% quoted lack of evidence as the greatest obstacle to clinical decision-making when dealing with unilateral synostosis.

Conclusion:
This survey exposes the lack of consensus and the disparity of opinion among craniofacial surgeons regarding the management of nonsyndromic coronal synostosis, particularly in the setting of recurrence.