bluuebunny/crossref_metadata_2025_split huggingface dataset:
Seven-Up Is a Novel Regulator of Insulin Signaling
Authors: Musselman Laura Palanker , Fink Jill L , Maier Ezekiel J , Gatto Jared A , Brent Michael R , Baranski Thomas J 
Published: February 2018

AbstractMusselman et al. address the overarching question: “What’s so bad about a high-calorie diet?” Using computational biology to analyze mRNA expression profiles, the authors built a Drosophila fat body gene regulatory network that predicted...Insulin resistance is associated with obesity, cardiovascular disease, non-alcoholic fatty liver disease, and type 2 diabetes. These complications are exacerbated by a high-calorie diet, which we used to model type 2 diabetes in Drosophila melanogaster. Our studies focused on the fat body, an adipose- and liver-like tissue that stores fat and maintains circulating glucose. A gene regulatory network was constructed to predict potential regulators of insulin signaling in this tissue. Genomic characterization of fat bodies suggested a central role for the transcription factor Seven-up (Svp). Here, we describe a new role for Svp as a positive regulator of insulin signaling. Tissue-specific loss-of-function showed that Svp is required in the fat body to promote glucose clearance, lipid turnover, and insulin signaling. Svp appears to promote insulin signaling, at least in part, by inhibiting ecdysone signaling. Svp also impairs the immune response possibly via inhibition of antimicrobial peptide expression in the fat body. Taken together, these studies show that gene regulatory networks can help identify positive regulators of insulin signaling and metabolic homeostasis using the Drosophila fat body.
Diş Hekimliği Fakültesi Son Sınıf Öğrencileri ve Diş Hekimlerinin Maksillofasiyal Travma Muayenesi Konusunda Bilgi Düzeylerinin Değerlendirilmesi
Authors: SARUHAN Nesrin , GÜRBÜZ URVASIZOĞLU Gelengül , ATAOL Mert , TEMİZ Mustafa 
Published: February 2018

Amaç: Bu çalışmanın amacı diş hekimliği fakültesi son sınıf
öğrencileri ve mezun diş hekimleri için maksillofasiyal travmalara yaklaşım ile
ilgili bilgi düzeylerini değerlendirmektir. Yöntem: Atatürk Üniversitesi
Diş Hekimliği Fakültesinde son sınıfta okuyan öğrenciler ve Erzurum ilinde
çalışmakta olan diş hekimlerine, maksillofasiyal travma bilgi düzeylerini ve
yaklaşımlarını değerlendirmek amacıyla hazırlanan 20 soruluk bir anket formu
uygulandı. Çalışmada 91 son sınıf öğrencisi ve 51 mezun diş hekimi yer almıştır. Bulgular: Bilgi düzeyini değerlendiren 13 sorudan 11 tanesine
verilen cevaplarda, doğru cevabın daha çok tercih edildiği görülmüştür. Sadece
2 soruda yanlış cevap seçeneği daha çok tercih edilmiştir. Katılımcılara
yöneltilen ve klinik yaklaşımı değerlendiren 7 adet subjektif değerlendirme
sorularının tamamı için, her iki grup tarafından da negatif sonuçlar elde
edilmiştir.

Sonuç: Hem son sınıf öğrencisi hem de mezun diş hekimlerinin
maksillofasiyal travmalar konusundaki bilgi düzeylerinin kabul edilebilir
olmasına rağmen katılımcıların bu konuda yeterli özgüvene sahip olmadıkları
görülmüştür. Bu konudaki teorik bilgilerin, klinik olarak güçlendirilmesi
gerektiği ve gereken eğitim stratejisinin oluşturulması gerekliliği sonucuna
varılmıştır.
Comparison of Elastane Fiber with Polyprolene and Polyglecaprone 25 used as Surgical Suture Material: an experimental preliminary study
Authors: Kabalcı Mehmet , Günal Nesimi , Günal Yasemin Dere , Bolat Ali , Balcı Mahi , Özpolat Berkant , Dural Koray , Yörübulut Serap , Eroğlu Erdinç 
Published: February 2018

Aim: Elastane fiber is a synthetic monofilament
polymer which is durable and highly flexible.
In this preliminary
study we compared
Elastane fiber with polypropylene and polyglycaprone 25, surching the inflammatory reaction
in the rat soft tissue,
considering that it could be used for sternal closure
because of its properties. Material and Methods:
Elastane fiber, polypropylene and polyglycaprone25 sutures
were placed in 3 separate
areas at 2 cm intervals
in the subcutaneous
tissue of each 8 male wistar albino
rats without any incision, using the seldinger
method. After two weeks, the rats were sacrified and tissue specimens,
including the suture
fragments, were resected.
Histopathological
scoring in terms of inflammation,
vascularization, fibrosis and histiocytic reaction
were achieved semiquantitatively. Results: There was no statistically significant
difference between three suture materials
in terms of inflammation (p=0.513), vascularization (p=0.065), fibrosis
(p=0.108) and histiocytic reaction
(p=0.630).

Conclusion: As a conclusion
elastane fiber showed similar
inflammatory changes with other suture
materials in the rat soft tissue which is thought
to be useful
for sternal closure
due to its high flexibilityand durability.
EDUCA��O MUSICAL E FORMA��O ESCOLAR: CONTRIBUI��ES DO PENSAMENTO FREIREANO E DO MULTICULTURALISMO CR�TICO
Authors: Carvalho Celso Do Prado Ferraz de , Carvalho Mauricio Braz de 
Published: February 2018

RESUMO
O objeto deste artigo foi problematizar o retorno do ensino musical � Educa��o b�sica brasileira. Tendo como foco o universo sociocultural da escola p�blica, o texto buscou situar as possibilidades e limites da forma��o musical a partir de uma compreens�o mais ampla sobre o processo de constru��o social da Escola p�blica brasileira, da apreens�o de suas determina��es hist�rico-sociais e das insufici�ncias marcantes nessa expans�o. Referiu criando o pensamento de Paulo Freire e o multiculturalismo cr�tico de Peter McLaren, analisou a Educa��o musical em perspectiva hist�rica, situando-a no contexto dos embates mais amplos pela defini��o da cultura e do curr�culo escolar.
Palavras-chave: Educa��o Musical; Escola P�blica; Curr�culo; Multiculturalismo.
Prácticas de enseñanza mediadas por la tecnología. Cómo enseñan los docentes en los foros de discusión de cursos que se desarrollan en modalidad a distancia
Authors: Mazzotti Wellington 
Published: February 2018

En este trabajo se exhiben los resultados de una investigación realizada sobre las prácticas de enseñanza que llevaron a cabo diferentes profesores en foros de discusión de cursos que se desarrollaron en modalidad a distancia, en tres instituciones educativas, dos argentinas y una uruguaya, con propuestas y formatos bien diferentes. Los foros estudiados eran cerrados, y en ellos participaron únicamente los alumnos inscriptos en los cursos. En la investigación subyace la concepción de que el foro es una de las herramientas centrales en una propuesta de educación a distancia. Su potencia radica en que a través de él se puede vertebrar la socialización del grupo virtual, perfilando una comunidad de sujetos todos ellos relacionados entre sí y con el objetivo común de construir conocimiento. Esta comunicación describe las observaciones realizadas y el análisis efectuado sobre las intervenciones de docentes en los foros estudiados en el marco de la investigación. Entre otras consideraciones, se muestra cómo el papel del docente trasvasa la propuesta institucional: con un mismo formato de curso, los docentes asumen roles bien diferentes y conducen los foros en forma tan distintas que los alcances que logran difieren sustancialmente unos de otros. Hemos observado cómo algunos docentes se transforman en verdaderos faros que iluminan el camino a seguir, en cambio otros asumen un papel de contertulio, adoptando casi la posición de un integrante más en una tertulia temática. Las acciones de algunos docentes están centradas en el trabajo sobre el error, utilizando técnicas sutiles y bien delineadas para cuidar y fortalecer las comunicaciones, mientras que otros despliegan una técnica que hemos denominado “docente al rescate” destinada a dinamizar el foro y a profundizar los intercambios que ocurren en él.
A CRIAÇÃO DA NACIONALIDADE NO SISTEMA INTERAMERICANO
Authors: Galvão Vivianny Kelly 
Published: February 2018

<p>O presente artigo trata das contribuições do sistema interamericano na regulamentação internacional da nacionalidade. O principal objetivo é demonstrar que o direito americano exerceu e continua exercendo um papel inovador para o direito internacional, principalmente sob a perspectiva da democratização. Para tanto foi usada metodologia de viés quantitativo, com destaque do método hipotético-dedutivo. Os resultados colhidos foram agrupados em dois grupos principais, o primeiro mais conceitual e o segundo voltado à análise da eficácia dos conceitos construídos. Esta segunda parte está representada pela tabela que traz a prática, em regra constitucional, dos Estados na regulamentação da nacionalidade e pelos estudos de casos colhidos na Corte Interamericana de Direitos Humanos. A principal conclusão é que o sistema interamericano traz uma inovação humanista à regulamentação da nacionalidade porque impõe aos Estados signatários da Convenção Americana de Direitos Humanos limites ao poder de regular a atribuição e a perda desse vínculo. A pesquisa tem originalidade porque foi desenvolvida na ocasião da participação da autora no <em>Centre for Studies and Research in International Law and International Relations</em> da Academia de Direito Internacional de Haia em 2016 cujo tema debatido foi a regulamentação internacional da nacionalidade. </p>
Pasivo sobrevenido: sociedad (todavía) en liquidación y responsabilidad de antiguos socios y liquidadores A propósito de la STS 324/2017, de 24 de mayo
Authors: Alonso Espinosa Francisco José 
Published: February 2018

Hay una más o menos cuestionable praxis de los empresarios de construcción que es la subyacente en el supuesto de hecho de la sentencia de referencia. Con el fin de dificultar el ejercicio de posibles acciones de responsabilidad contractual derivada de defectos o vicios ocultos de las edificaciones que realizan o promueven, tales empresarios constituyen sociedades ocasionales (casi instrumentales) cuyo objeto social es la realización de una determinada y concreta edificación o, acaso, un pequeño grupo de ellas. Una vez vendida la misma (viviendas, normalmente), tales empresarios casi “ocultos” tras tales sociedades ocasionales proceden a disolverlas por conclusión de su objeto social, son liquidadas y formalmente extinguidas mediante cancelación de sus asientos registrales.
Support My Spine ASAP. A Rural Tele-health care model for patients being managed with a Thoracic Lumbar Sacral Orthotic (TLSO)
Authors: Gallagher Ryan , Morison Jane , Giles Michelle , Henderson Judith , Zehnder Sarah 
Published: February 2018

Abstract

Question
Does a Telehealth model of care facilitating treatment in rural hospitals for patients requiring a TLSO eliminate the need for transfer to a tertiary referral hospital?

Design
Quantitative pre and post intervention design.

Participants
Physiotherapists, nursing and medical staff at rural hospital pilot sites.

Intervention
Pre and post intervention data collection provided patient demographics, and length of stay data around model of care implementation. Pre intervention staff surveys identified knowledge gaps informing educational packages which were provided with a mobile Telehealth link.

Outcome measures
Primary: Number of patients managed under the new model of care. Secondary: Length of stay, travel distance eliminated and complications.

Results
30 patients fitted with TLSO’s and managed under this model of care to date. Length of stay has reduced from 9.14 days pre intervention to 3.8 days post intervention. Approximate savings of $6840 per patient have been identified, with over 6000kms of patient travel eliminated. No complications have occurred. Rural Physiotherapists have been successfully up skilled in managing patients requiring TLSO fitting.

Conclusion
This intervention successfully created a model of care to facilitate local management of patients requiring TLSO fitting with Telehealth support from a tertiary referral hospital. Considerable savings have occurred from this model of care for patients and the health district. This model is currently being implemented district wide.

Key Practice Points

Telehealth model of care can be successfully implemented to TLSO management

Multidisciplinary team role is critical role in redesigning models of care

Telehealth increase the efficiency of healthcare resources
Neuroscience Nursing in Indonesia: Striving for Recognition through Education and Regional Collaboration
Authors: Nichols Linda , Mulyatsih Enny 
Published: February 2018

Abstract
As a speciality practice area, neuroscience nursing is internationally recognised. In 2014 the Australasian Neuroscience Nurses Association celebrated its 40th anniversary. For Indonesian neuroscience nurses, 2014 marked the inaguration of the Indonesian Neuroscience Nurses Association. The following paper provides an overview of health care in Indonesia and development of neuroscience nursing as a specialty through educational and regional collaboration. Postgraduate educational opportunities are open to all nurses in Australia, including neuroscience as a specialty for nurses. However within Indonesia, the focus has been on meeting basic nursing demands, with postgraduate specialisation still in its infancy. The focus on training and producing large numbers of nurses at a basic level has resulted in little regard for the ongoing development and acknowledgement of speciality practice areas, such as neuroscience nursing. The following paper outlines the challenges faced by Indonesian nurses as they strive towards the recognition of neuroscience nursing as a speciality. Through the provision of an overview of current nursing and the health care system in Indonesia, this paper will explore the geographical, economic, political and cultural factors that require consideration when translating experience and expertise.
iPhone video link FaceTime as an orientation tool: Remote O&M for people with vision impairment
Authors: Holmes Nicole , Prentice Kelly 
Published: February 2018

Abstract

Two case study participants investigated the effectiveness of the Application “FaceTime” as an O&M tool via the Apple iPhone. The participants included a traveller (blind) who is an experienced long cane and guide dog user; and a qualified O&M instructor. The traveller and instructor tested FaceTime in five varying scenarios including shop identification, product identification in a supermarket, identification of buses at a transport interchange, orientation while free walking in residential streets, and road intersection identification. It was found that the information provided remotely by the instructor enhanced the independence of the traveller since it could not be obtained via GPS or other means.
Effective mobility framework: A tool for designing comprehensive O&M outcomes research
Authors: Deverell Lil , Bentley Sharon A. , Ayton Lauren N. , Delany Clare , Keeffe Jill E. 
Published: February 2018

Abstract

In orientation and mobility (O&M) outcomes research, the concept of mobility has become narrowed to what can be captured with existing measures and methods. However, travel speed and contact tallies have not provided convincing evidence of functional changes resulting from O&M programs or such vision restoration treatments as retinal prostheses. This study used grounded theory methodology to develop a new understanding of mobility from expert opinions, including O&M specialists (n=15) and adults (n=40) with advanced retinitis pigmentosa. The Effective Mobility Framework includes the elements of Utility, Access, Orientation, Interdependence, Self-regulation, Efficiency, and Pleasure representing a more comprehensive understanding of O&M outcomes than previously used. The Framework highlights the importance of mixed methods data collection and the need for new types of ordinal measure in researching functional outcomes.
A clock-face method of outdoor scanning and tracking using sports cones: A case study of a client with post-stroke visual field loss
Authors: Hower Sarah , Still Ross 
Published: February 2018

Abstract

The participant in this case study is a 65 year old male, who had a right posterior cerebral artery stroke. He undertook a compensatory scanning program though continued to experience collisions with objects in familiar and unfamiliar environments. He was later referred to Guide Dogs NSW/ACT, Australia for orientation and mobility (O&M) services. The second author (instructor) assessed and identified this client’s functional field of vision using an outdoor clock-face method by placing sports cones of various colours on the ground in front of the client at specific distances. The clock-face method was also used to facilitate consistent and effective scanning and tracking training in environments of various complexities in which the participant needed to travel. Importantly, the scanning and tracking technique commenced at the client’s feet, assisting him to avoid tripping and falling. Post-training, the client reported that he is more aware of his visual field deficit to the extent that he was surprised his visual field had not actually increased. He has not reported any falls or collisions post-training and experiences increased confidence travelling in the community.
Conditions that influence drivers’ yielding behaviour: Effects of pedestrian gaze and head movements
Authors: Bourquin Eugene A. , Emerson Robert Wall , Sauerburger Dona , Barlow Janet 
Published: February 2018

Abstract
These studies examined the effects of various types of pedestrian gazing toward vehicles and drivers at traffic signal-controlled intersections and a roundabout, measuring driver delays (seconds) and yielding behaviours. No statistical or practical differences were found between any of the gaze conditions and no-gaze conditions. These findings might have practical application for orientation and mobility (O&M) specialists and students. Pedestrians who are blind or vision impaired who benefit from a forward-facing head position to align, or who must turn their heads to visually monitor potential threats from turning vehicles, need not be apprehensive that their head movements or gazing will likely reduce the drivers’ yielding.
There’s more to a dog guide than meets the eye: A preliminary exploration of potential health benefits of dog guide use
Authors: Lane Geraldine , Matthews Brian , Ellison Caroline , Palmer Carolyn 
Published: February 2018

Abstract
The value of dog guides in terms of mobility for people with severe vision impairment and blindness is well recognised. There has, however, been a paucity of research exploring the potential health benefits of working with dog guides. This article reports the initial stage of a research project, which aimed at redressing this dearth of research. The study used three focus groups to explore the experiences of 22 participants from three Australian states. The focus group meetings were the first of three components of a major research project into this important issue. The outcomes reflected a self-reported trend toward enhanced health and wellbeing for people who use dog guides as their primary mobility aid.
Self-Tuning Control of an Electro-Hydraulic Actuator System
Authors: Ghazali R. , Sam Y. M. , Rahmat M. F. , Jusoff K. , Zulfatman  , Hashim A. W. I. M. 
Published: February 2018

Abstract
Due to time-varying effects in electro-hydraulic actuator (EHA) system parameters, a selftuning control algorithm using pole placement and recursive identification is presented. A discrete-time model is developed using system identification method to represent the EHA system and residual analysis is used for model validation. A recursive least square (RLS) method with covariance resetting technique is proposed to estimate parameters of the discrete-time model. The results show the proposed control algorithm can adapt the changes occur in model parameters compared with the fixed controller.
In conclusion, a self-tuning control is required in improving the EHS system performance in industrial positioning applications.
A wireless inductive-capacitive (L-C) sensor for rotating component temperature monitoring
Authors: Rodriguez Rogie I. , Jia Yi 
Published: February 2018

Abstract
Temperature monitoring is critical in almost every type of machinery and application, especially in rotating components such as jet turbines, engines, and power plants, etc. These components involve harsh environments and where the physical connections for monitoring systems are impossible. This paper presents a resonant inductive-capacitive (L-C) circuit based wireless temperature sensor suitable for working in these harsh environments to monitor the temperature of rotating components. Design and performance analysis of the wireless temperature sensor has been conducted and the sensor prototype was successfully fabricated and calibrated up to 200°C with sensitivity of 30 kHz/°C. As a result it is confirmed that temperature monitoring of a rotating component can be carried out without requiring physical connection, power supplies or active elements in the sensor circuit.
Measurement of Stress-Strain Response of a Rammed Earth Prism in Compression Using Fiber Bragg Grating Sensors
Authors: Guru Prasad A. S. , Anitha M. , Nanjunda Rao K. S. , Asokan S. 
Published: February 2018

Abstract
A comparative study of strain response and mechanical properties of rammed earth prisms, has been made using Fiber Bragg Grating (FBG) sensors (optical) and clip-on extensometer (electro-mechanical). The aim of this study is to address the merits and demerits of traditional extensometer vis-à-vis FBG sensor; a uni-axial compression test has been performed on a rammed earth prism to validate its structural properties from the stress - strain curves obtained by two different methods of measurement. An array of FBG sensors on a single fiber with varying Bragg wavelengths (λB), has been used to spatially resolve the strains along the height of the specimen. It is interesting to note from the obtained stress-strain curves that the initial tangent modulus obtained using the FBG sensor is lower compared to that obtained using clip-on extensometer. The results also indicate that the strains measured by both FBG and extensometer sensor follow the same trend and both the sensors register the maximum strain value at the same time.
Accuracy Comparison of ARX and Anfis Model of an Electro-Hydraulic Actuator System
Authors: Rahmat M. F. , Ling T. G. , Husain A. R. , Jusoff K. 
Published: February 2018

Abstract
Precise control of electro-hydraulic actuator (EHA) system has been an interesting subject due to its nonlinearities and uncertainties characteristics. Good control can be designed when precise model of the system is available. Linear ARX modelling has widely been applied and satisfying result has been obtained, through linearization process. The objective of this paper is to compare ARX model with nonlinear ANFIS (Adaptive Neuro-Fuzzy Inference System) model, which can represent the real EHA system more precisely using same linearized data. Results show that ANFIS model is more accurate in approximation estimation of EHA system than ARX model on linearized data.
Type-2 Fuzzy Kalman Hybrid Application for Dynamic Security Monitoring Systems based on Multiple Sensor Fusion
Authors: Dakhlallah T. K. , Zohdy M. A. , Salim O.M. 
Published: February 2018

Abstract
Multiple sensors fusion plays a major role in situation awareness, especially in modern dynamic security monitoring and tracking applications. In this paper, we focus on a specific effective set of complementary sensors [Laser (for speed measurements), Sonar (for space scanning) and RF (for access rights)]. A novel multi-agent system is obtained by fusing the above types of sensory data taking advantages of similarity and complementarity concepts. Furthermore, Kalman Filter is utilized to track next state estimates of agent(s) in uncertain environment. Finally, our proposed system transforms system state to be able to make a security awareness decision, using type-2 fuzzy logic system to handle exhibited uncertainty, for asset scenery under surveillance. It is shown that the system performance can exhibit promising improvements for this dynamic security monitoring situation as a result of using the above complementary heterogeneous set of sensors.