bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Amenity Value of Bicycle Infrastructure: A Hedonic Application to Greater Manchester, UK
Authors: Hearne David , Yerushalmi Erez 
Published: November 2024

Abstract
Using hedonic and spatial regressions, this paper estimates a significantly larger association between proximity to bicycle networks and property prices than previously reported. As cities face increasing challenges of congestion and pollution, many are implementing policies to integrate bicycle facilities and other active modes of transport. However, policymakers are slow to support these initiatives and remain skeptical due to the investment costs required and appropriation of limited land. Drawing on a large dataset of approximately 253,000 transactions in Greater Manchester, over a 9-year period, we find clear evidenced that a 1 km reduction in distance to the nearest bicycle network is associated with property values being around 2.8% higher, on average, and 7.7% higher in the central borough of Manchester. We also provide an applied example to rank new bicycle routes by comparing their benefit-to-cost ratios and a discussion on the property tax system.
Profile of urban sustainability in Bulgaria
Authors: Rodrigues Margarida , Franco Mário , Filipova Hristina , Silva Rui Jorge , Kazandzhieva Velina , Nacheva Radka , Koleva Velina , Lyubenov Lyubomir , Oliveira Cidália , Borges Ana Pinto , Braga José , Ivanova Pavlina , Antonova Katya 
Published: November 2024

AbstractSustainability is becoming increasingly relevant due to the need to decide on planned management of land use and natural resources as well as sustainable development in the context of cities. This study aims to identify indicators for measuring the sustainable development of districts/countries in Bulgaria. Using the Multivariate Analysis (MVA) method, where we examine multiple variables in several dimensions, the results show that in the environmental pillar, the management of natural resources, including water and soil, was under pressure due to industrial and urban activities. Air quality and waste management were also critical issues in some urban areas. The promotion of sustainable building practices and the adoption of renewable energies could be areas of focus for improving environmental sustainability in Bulgarian cities. This study is innovative becouse it underscores the imperative need for urban sustainability to integrate the foundational pillars of sustainability harmoniously. Central to this integration is the cultivation of economic growth that upholds environmental integrity and fosters social equity and opportunity. More theorectical and managerial contributios are also presented.
How Accurate are Your Experimental Data? A More Accessible GUM-Based Methodology for Uncertainty Evaluation
Authors: Bernardini Luca , McLinden Mark O. , Yang Xiaoxian , Richter Markus 
Published: November 2024

AbstractA methodology for evaluating experimental uncertainty is presented. Based on the Guide to the Expression of Uncertainty in Measurement (GUM) in conjunction with a sensitivity analysis, this method readily applies to systems of various degrees of complexity. It consists of three steps: (1) to estimate each uncertainty contribution of the system based on GUM; (2) to determine the sensitivity of the calculated results to variations in each of the input measurands in turn, replacing the partial derivatives of the GUM with a purely numerical approach; and (3) to calculate the overall uncertainty using the error propagation principle. Furthermore, the calculated sensitivity coefficients enable a critical evaluation of the investigated system, allowing the detection of possible targeted improvements. For this reason, the presented method is called “the sensitivity analysis method.” This is applied to three case studies with increasing complexity: a mass calibration procedure, a volume calibration procedure, and a gravimetric densimeter characterized by a multi-parameter nonlinear measuring model. When possible, the results are compared to the GUM uncertainty framework or values available in the literature.
A physics-guided deep generative model for predicting melt pool behavior in laser powder bed fusion additive manufacturing
Authors: Kim Jaehyuk , Yang Zhuo , Lu Yan 
Published: November 2024

AbstractLaser powder bed fusion (LPBF) is a promising metal additive manufacturing process that enables the production of highly intricate geometries. Achieving consistent quality and repeatability in LPBF lies in accurately predicting and controlling melt pool behavior. Recent studies have primarily utilized data-driven approaches using real-time melt pool monitoring (MPM) data. However, these methods often lack accuracy and interpretability, primarily because they rely on data without adequately considering the underlying physical mechanisms related to melt pool formation. To address this issue, our study introduces a novel physics-guided deep generative model to predict melt pool behavior in LPBF. We employ a Convolutional Neural Network Transformer Generative Adversarial Network to predict future MPM images, leveraging a physics-based model to enhance the accuracy and interpretation of our predictions. Our experimental validation highlights the model’s effectiveness and accuracy in predicting melt pool behaviors in LPBF. A comparison with related studies shows that the proposed model achieves better prediction accuracy, demonstrating improvements in melt pool geometry and image quality. This advancement in melt pool modeling significantly contributes to the LPBF, promising to improve its process control and part quality.
Identifying latent subgroups of primary head injury: an explorative latent class analysis on neuropathologically examined medico-legal autopsy cases
Authors: Laakko Essi , Oura Petteri 
Published: November 2024

AbstractTraumatic brain injury (TBI) is a significant global health concern and frequently encountered in medico-legal autopsies. Previous studies suggest that certain TBI subtypes are more likely to co-occur than others. Therefore, we aimed to explore the potential of latent class analysis (LCA) to identify and characterize primary head injury combinations in neuropathologically examined medico-legal autopsy cases. The dataset comprised 78 cases from the Forensic Medicine Unit of the Finnish Institute for Health and Welfare over the period of 2016–2022. Data on background and circumstantial characteristics as well as primary and secondary head and brain injuries were collected from police documents, medical records, general autopsy reports and neuropathology reports. Latent class solutions with two to five classes were explored to identify clustering of primary head injuries among the sample. The dataset comprised 69.2% males and the median age was 49 years. In LCA, the solutions appeared reasonable, and each class appeared to represent a distinct TBI profile. The two-class solution was found to fit the present dataset best. Class 1 was characterized by older age, presence of an underlying CNS disease, and less diverse primary head injuries; these were interpreted as suggestive of lower traumatic forces. Class 2 was characterized by male sex and assaults as a prominent injury circumstance; subarachnoid and intracerebral/ventricular haemorrhages and contusions were classified exclusively into this class. In conclusion, this study identified two distinct subgroups of primary head injuries. Understanding typical injury combinations related to distinct circumstances could assist not only forensic pathologists but also clinicians treating TBI patients. However, the present latent class solution should not be interpreted as “ground truth”, but instead further research is needed.
The Role of Zooplankton Community Composition in Fecal Pellet Carbon Production in the York River Estuary, Chesapeake Bay
Authors: Sharpe Kristen N. , Steinberg Deborah K. , Stamieszkin Karen 
Published: November 2024

AbstractZooplankton play a key role in the cycling of carbon in aquatic ecosystems, yet their production of carbon-rich fecal pellets, which sink to depth and can fuel benthic community metabolism, is rarely quantified in estuaries. We measured fecal pellet carbon (FPC) production by the whole near-surface mesozooplankton community in the York River sub-estuary of Chesapeake Bay. Zooplankton biomass and taxonomic composition were measured with monthly paired day/night net tows. Live animal experiments were used to quantify FPC production rates of the whole community and dominant individual taxa. Zooplankton biomass increased in surface waters at night (2- to 29-fold) due to diel vertical migration, especially by Acartia spp. copepods. Biomass and diversity were seasonally low in the winter and high in the summer and often dominated by Acartia copepods. Whole community FPC production rates were higher (3- to 65-fold) at night than during the day, with the 0.5–1 mm size class contributing 2–26% to FPC production in the day versus 40–70% at night. An increase in the relative contribution of larger size fractions to total FPC production occurred at night due to diel vertical migration of larger animals into surface waters. Community FPC production was highest in fall due to increased diversity and abundance of larger animals producing larger fecal pellets, and lowest in summer likely due to top-down control of abundant crustacean taxa by gelatinous predators. This study indicates that zooplankton FPC production in estuaries can surpass that in oceanic systems and suggests that fecal pellet export is important in benthic-pelagic coupling in estuaries.
Expert consensus for pertussis in children: new concepts in diagnosis and treatment
Authors: Mi Yu-Mei , Deng Ji-Kui , Zhang Ting , Cao Qing , Wang Chuan-Qing , Ye Sheng , Chen Ying-Hu , He Han-Qing , Wu Bei-Bei , Liu Yan , Zeng Mei , Li Wei , Wu Fang , Xu Hong-Mei , Zhao Shi-Yong , Liu Gang , Hua Wang , Xu Dan , Bai Guan-Nan , Yang Ying , Huang Li-Su , Chen Yi-Ping , Yao Kai-Hu , Shao Zhu-Jun , Hua Chun-Zhen 
Published: November 2024

Abstract
Background
Pertussis resurgence has been reported worldwide in the past two decades. Pertussis is still endemic and difficult to control though with universal vaccination in children. The resurgence may be related to multiple variables, such as increased disease awareness and laboratory tests, waning of immunity following vaccination, and/or genetic mutations of Bordetella pertussis. For better pertussis prevention, diagnosis, and management, we called up an expert panel to develop this expert consensus to provide new concepts in diagnosis and treatment for clinical practice.

Data sources
The expert groups collected clinical evidence, summarized their clinical experiences, evaluated preliminary recommendations or guidelines, and then organized open-ended discussions to form the recommendations. This consensus was developed by reviewing the literature and studies in databases, including PubMed, Cochrane, EMBASE, the China Biomedical Database, and the Chinese Journal Full-text Database up to May 2024. The search terms included “pertussis” or “whooping cough”, “children”, “diagnosis”, and “treatment”.

Results
The burden of pertussis has also changed from infants to school children and adults, and these age groups have consequently become the main source of infection for vulnerable population including infants and newborns. In China, a high prevalence of erythromycin-resistant Bordetella pertussis (ERBP) has been reported in the past decade. ERBP may lead to failed clinical empirical treatment with macrolides, which poses a great challenge for pertussis management and control. For better management of pertussis, a flow diagram for diagnosis and treatment of pertussis was presented in this consensus. This consensus also described the diagnostic criteria for pertussis, high-risk cases, and severe pertussis. Macrolides can still be used to treat confirmed erythromycin-sensitive B. pertussis (ESBP) infections, whereas oral trimethoprim–sulfamethoxazole therapy is the initial treatment option for children older than two months. For infants younger than two months, severe patients, or those exhibiting a high degree of sulfonamide allergy, intravenous administration of piperacillin or cefoperazone–sulbactam is advised.

Conclusions
This expert consensus provides a comprehensive guidance and a reference for the diagnosis and treatment of pertussis in children.

Graphic abstract
Still doing it yourself? Investigating determinants for the adoption of intelligent process automation
Authors: Mayr Alexander , Stahmann Philip , Nebel Maximilian , Janiesch Christian 
Published: November 2024

AbstractIntelligent process automation (IPA) augments symbolic process automation using artificial intelligence. Emulating human decision-making, IPA enables the execution of complex processes requiring decision-making capacities. IPA promises great economic potential as it enables more efficient use of the human workforce. However, the adoption rate in practice falls behind these potentials. Our study aims to investigate reasons and identify areas for action towards IPA adoption. To this end, we identified 13 determinants and created an extended UTAUT model. We tested the model with partial least squares structural equation modeling for significant influential relationships between the determinants based on a user study. We contribute to theory and practice finding a special role of trust and transparency for the adoption of IPA. Likewise, we show that organizations should cultivate a positive attitude towards IPA diffusion. Further, our results contribute with a focus on the potential adopters as IPA adoption is contingent upon their characteristics, such as experience and job level.
Infants < 90 days of age with late-onset sepsis display disturbances of the microbiome-immunity interplay
Authors: Graspeuntner Simon , Lupatsii Mariia , van Zandbergen Vera , Dammann Marie-Theres , Pagel Julia , Nguyen Duc Ninh , Humberg Alexander , Göpel Wolfgang , Herting Egbert , Rupp Jan , Härtel Christoph , Fortmann Ingmar 
Published: November 2024

Abstract
Objective
We hypothesized that previously healthy infants < 90 days of age with late-onset sepsis (LOS) have disturbances of the gut microbiome with yet undefined specific immunological patterns.

Methods
We performed a prospective single-center convenience sample study between January 2019 and July 2021 in a case-control design. Routine diagnostics included conventional cultures (blood, cerebrospinal fluid, urine), PCRs and inflammatory markers in infants aged < 90 days with clinical LOS. We additionally analyzed blood lymphocyte subsets including CD4 + CD25 + forkhead box protein (FoxP3)+ Tregs and performed 16 S rRNA sequencing of stool samples, both compared to age-matched healthy controls. Results were adjusted for potential confounders that may influence microbial composition.

Results
51 infants with fever and clinical LOS were enrolled. Bacterial sepsis was diagnosed in n = 24 (47.1%) and viral infection in n = 13 (25.5%) infants, whereas in 14 (27.3%) infants the cause of fever remained undetermined. When compared to healthy controls, the gut microbiome of LOS infants at disease onset was characterized by a shift in community composition, specifically, decreased abundance of B. longum and an increase of Bacteroidia spp. Intriguingly, the abundance of B. longum negatively correlated with the frequency of blood CD4-positive cells in healthy controls but not in infants with LOS. At one year of age, we observed microbiome differences in infants with history of LOS when compared to healthy controls, such as an increased gut microbial diversity.

Conclusion
Our data suggest potential signatures of the microbiome-immunity interplay in infants with LOS, which should be investigated further as possible targets for prevention.
Induratio penis plastica – Ätiologie, Symptome, Diagnostik und Therapie
Authors: Heining Franziska , Hunziker Manuela , Eberli Daniel 
Published: November 2024

ZusammenfassungDie Induratio penis plastica – auch unter dem Eigennamen Peyronie-Krankheit bekannt – ist eine Erkrankung des älteren Mannes, welche durch die Ausbildung von Plaques in den Schwellkörpern zu einer Verkrümmung des Penis führt. Die Ursache der Erkrankung ist nicht abschliessend geklärt, wobei wiederholte Mikrotraumata ebenso eine Rolle spielen können wie genetische Faktoren sowie Stoffwechselerkrankungen. Zu den typischen Symptomen zählen die häufig schmerzhafte Verbiegung des Penis – insbesondere im erigierten Zustand – bis hin zur Unmöglichkeit eines penetrativen Geschlechtsverkehrs sowie die erektile Dysfunktion. Zur Diagnosestellung gehören eine detaillierte Anamnese, die körperliche Untersuchung sowie wahlweise bildgebende Verfahren. Eine gründliche Diagnosestellung ist essenziell, um andere Ursachen für die Symptome auszuschliessen sowie einen optimalen individuellen Behandlungsplan für jeden Patienten zu erstellen.Die Induratio penis plastica verläuft typischerweise in 2 Phasen: der akuten Phase, die durch Schmerzen, aktive Entzündung und sich entwickelnde Krümmung gekennzeichnet ist, und der chronischen Phase, in der sich die Symptome stabilisieren und die Schmerzen nachlassen. Die Behandlung der Erkrankung variiert je nach Phase und zielt darauf ab, Schmerzen zu lindern, die Verformung zu korrigieren und die erektile Funktion zu verbessern. Zu den konservativen Massnahmen zählen orale Therapien und Injektionstherapien sowie Verfahren mit Stosswellen. Bei den chirurgischen Prozeduren unterscheitet man Verfahren der Penisverkürzung von solchen zum Erhalt der Penislänge. In Fällen einer therapieresistenten erektilen Dysfunktion sind Penisprothesen die Methode der Wahl.Die Induratio penis plastica ist eine komplexe Erkrankung. Der Verlauf sowie die Prognose sind sehr variabel, und betroffene Männer entwickeln einen unterschiedlich stark ausgeprägten Leidensdruck. Eine frühzeitige Diagnose und Behandlung können helfen, die Symptome zu lindern und die Lebensqualität der Patienten zu verbessern.
Spatiotemporal analysis of Zika virus transmission dynamics incorporating human mobility and seasonal variations using modified homotopy perturbation method
Authors: Alaje Adedapo Ismaila , Olayiwola Morufu Oyedunsi , Odeleye John Femi 
Published: November 2024

AbstractThis study employed a mathematical model to evaluate how seasonal variations, vector dispersal, and mobility of people affect the spread of the Zika virus. The model's positive solutions, invariant zones, and solution existence and uniqueness were validated through proved theorems. The equilibria points were identified, and the basic reproduction number was calculated. The model was semi-analytically solved using a modified homotopy perturbation approach, and an applied convergence test proved that the solution converges. The simulation results indicated that under optimal breeding conditions, the density of healthy mosquitoes peaked in the fourth month. Two months later, increased mosquito dispersal and human carriers facilitated by favorable weather led to a rise in mosquito infectiousness, peaking between the fourth and eighth months due to significant seasonal effects, resulting in high Zika transmission. To effectively control mosquito populations and reduce Zika transmission, it is recommended that public health interventions focus on the critical periods spanning the third to eighth months.
Retrospective analysis of neonatal hyperbilirubinemia at Hiwot Fana Comprehensive Specialized Hospital, Ethiopia: prevalence, associated factors, and treatment outcome
Authors: Shugri Mohamed Abdirahman , Libe Temesgen Teferi , Gebru Feven Mekonnen 
Published: November 2024

Abstract
Background
Neonatal hyperbilirubinemia, a condition marked by yellow discoloration of the skin and eyes due to elevated bilirubin levels, poses significant risks including kernicterus, a severe form of bilirubin encephalopathy. Understanding its prevalence, associated factors, and outcomes is crucial for effective management.

Objectives
This study aimed to assess the prevalence, associated factors, and treatment outcomes of neonatal hyperbilirubinemia at Hiwot Fana Comprehensive Specialized Hospital, Eastern Ethiopia.

Methodology
A hospital-based, cross-sectional study was conducted. We reviewed the medical charts of 328 neonates admitted to the Neonatal Intensive Care Unit of Hiwot Fana Comprehensive Specialized Hospital between January 1, 2019, and December 30, 2020. Data were collected using a checklist and analyzed with SPSS version 22, employing descriptive statistics and logistic regression.

Result
The prevalence of neonatal hyperbilirubinemia was 44.2% (95% CI 38.9, 49.6). Sepsis (66.9%) and Rh incompatibility (4.8%) were prevalent among neonates with neonatal hyperbilirubinemia. Prematurity and age at admission were significantly associated with neonatal hyperbilirubinemia. Most neonates with neonatal hyperbilirubinemia (94%) were treated with phototherapy alone, while a smaller proportion (6%) required a combination of phototherapy and exchange transfusion. The overall improvement rate was 93.8%, with a mortality rate of 1.4% due to bilirubin encephalopathy.

Conclusion
Neonatal hyperbilirubinemia was prevalent among neonates admitted to Hiwot Fana Comprehensive Specialized Hospital, with significant associations to age at admission, prematurity, and sepsis. Effective management, including timely phototherapy and addressing resource shortages, is crucial to improving neonatal outcomes.
“Watch Your Tone!”: Music and Meaning in Bobi Wine’s “Tugambire ku Jennifer” and the Kampala Street Vendors
Authors: Lwanga Charles 
Published: November 2024

AbstractMusic enhances participation in emerging democracies where the rights of association, assemblage, and and the freedom of expression are suppressed by the state apparatus meant to guarantee them in the first place. Ugandan Afropop musician and politician, Robert Kyagulanya (aka Bobi Wine), composed the song “Tugambire ku Jennifer” (Tell Jennifer on Our Behalf), which articulated the social aspirations of Kampala’s street vendors. The song’s meaning does not begin and end with the composer’s intent but stretches to its effects on the listeners. Analyzing meaning through the lens of speech act theory provides an understanding of what music means when it simultaneously reflects and shapes society.