bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sleep disturbance subtypes in Parkinson’s disease based on the cross-culturally validated Korean version of the Parkinson’s Disease Sleep Scale-2
Authors: Yang Hui-Jun , Kim Han-Joon , Koh Seong-Beom , Kim Joong-Seok , Ahn Tae-Beom , Cheon Sang-Myung , Cho Jin Whan , Kim Yoon-Joong , Ma Hyeo-Il , Park Mee-Young , Baik Jong Sam , Lee Phil Hyu , Chung Sun Ju , Kim Jong-Min , Song In-Uk , Kim Ji-Young , Sung Young-Hee , Kwon Do Young , Lee Jae-Hyeok , Lee Jee-Young , Kim Ji Sun , Yun Ji Young , Kim Hee Jin , Hong Jin Young , Kim Mi-Jung , Youn Jinyoung , Kim Ji Seon , Oh Eung Seok , Yoon Won Tae , You Sooyeoun , Kwon Kyum-Yil , Park Hyung-Eun , Lee Su-Yun , Kim Younsoo , Kim Hee-Tae , Kim Sang Jin 
Published: February 2019

Abstract
Background: Sleep-related problems in Parkinson’s disease (PD) have received greater attention in recent years due to their clinical influence on morbidity, disability, and the health-related quality of life (HRQoL) of patients. This study aimed to evaluate the clinimetric properties of the Korean version of the Parkinson’s Disease Sleep Scale-2 (K-PDSS-2), and to analyze whether distinct sleep disturbance subtypes could be empirically identified in patients with PD based on the cross-culturally validated K-PDSS-2.
Methods: The internal consistency, test-retest reliability, scale precision, and convergent validity of the K-PDSS-2 were assessed in a nationwide, multicenter study of 122 patients with PD. Latent class analysis (LCA) was used to derive subgroups of patients who experienced similar patterns of sleep-related problems and nocturnal disabilities.
Results: The mean total K-PDSS-2 scores were 11.67 ± 9.87 (mean ± standard deviation) at baseline, and 12.61 ± 11.17 upon follow up testing. The Cronbach’s α coefficients of the total K-PDSS-2 score at baseline and at follow up testing were 0.851 and 0.880 respectively. Intraclass correlation coefficient over the 2-week period ranged from 0.672 to 0.848. The total K-PDSS-2 score was strongly correlated to HRQoL measures and other corresponding nonmotor scales. LCA indicated three distinct sleep disturbance classes in the study patients, namely “less troubled sleepers”, “PD-related nocturnal difficulties”, and “disturbed sleepers”.
Conclusions: The K-PDSS-2 showed good clinimetric attributes in accordance with prior studies that were using the original version of the PDSS-2, therefore confirming the cross-cultural usefulness of the scale. Further, this study documents the first application of an LCA approach for identifying sleep disturbance subtypes in patients with PD.
Keywords: Parkinson’s disease; sleep; PDSS-2; validity; reliability; Korean version; latent class analysis.
İşitme Kayıplı Çocuğu Olan Bir Annenin Aile Eğitimi Sürecinin İncelenmesi
Authors: TURAN Zerrin , KOCA Aslı , UZUNER Yıdız 
Published: February 2019

Bu
araştırmanın amacı işitme kayıplı çocuğu olan bir annenin, aile eğitimi
sürecinin incelenmesidir. Eylem araştırması olarak desenlenen çalışmanın
katılımcıları işitme kayıplı bir çocuğun annesi ve eğitimcidir. Araştırma
verileri, aile eğitimi uygulamalarının videoteyp kayıtları, anneyle yapılan
görüşmeler, geçerlik güvenirlik komitesi ses kayıtları ve araştırmacı
günlükleri yoluyla toplanmıştır. Araştırma sürecinde toplam on seans aile
eğitimi yapılmıştır. Aile eğitimi sürecinin incelenmesi amacıyla tüm seansların
genel dökümü yapılmış, elde edilen verilere tümevarım analizi uygulanmıştır.
Araştırma süresince her seans sonrası yazarlar arasında düzenlenen
toplantılarla seans süresince karşılaşılan sorunlar saptanmış ve yeni bir eylem
planı oluşturulmuştur. Oluşturulan eylem planı çerçevesinde bir sonraki aile
eğitimi planlanarak uygulanmıştır. Çalışma süresince bu döngü sistematik bir
şekilde sürdürülmüştür. Verilerin analizi sonucu 7 ana tema, 9 alt temaya ulaşılmıştır. On seans eğitim
sonrasında annenin çocuğun gelişimini destekleyen olumlu davranışlarında artış
ve eğitimcinin aile eğitimi uygulamasında olumlu değişikler gözlenmiştir.
Komitmen Organisasi pada Dosen Generasi Milenial
Authors: Sari Reza Lidia 
Published: February 2019

<p>In Human Resource Management, workers from the millennial generation, including those working as lecturers in Indonesia, are often studied with regard to their low level of organizational commitment. Millennial lecturers are often faced with various challenges that can trigger them to decide to quit their jobs and leave the college. This research aimed to discover the factors influencing millennial lecturers’ organizational commitment. The instruments used were the Organizational Commit­ment Scale, Job Satisfaction Survey, and Professional Commitment Scale. The respondents were 123 lecturers from 10 universities in Padang, Jakarta, and Bali, who were selected using purposive sampling technique. The analysis method used was a multiple regression analysis. The research findings showed that job satisfaction and professional commitment, to be exact, their satisfaction with supervisors, professional commitment continuance and normative professional commitment had a significant impact on these lecturers’ organizational commitment. The result of this study delivers important implications to universities in managing their millennial lecturers so that they can improve their organizational commitment.</p><p> </p><p> </p>
Nutritional composition, Taxonomical and phytoremediation status of Duckweed (Wolffia): Review
Authors: Pandey Amit , R.K. Verma 
Published: February 2019

Wolffia are the crucial in decline of a flowering plant having tiny, rootless spheres in 1 mm length (or less). Wolffia is commonly known as Watermeal because it look like small particles over the water. 5 species of Wolffia are found in Western United States, while 11 species all over world. Being taken from pond to pond on the feet of water fowl (tucked neatly under the ducks' bodies during flight), might describe the distribution of few Wolffia species. In the South eastern part of US, there are evidence of Wolffia plant being taken from tornado, and they had been reported in the water of melted hailstones. Our review were focus on the Nutritional aspects, Taxonomy, Phytoremediation of heavy metal and uses of different species of Wolffia plant.
SIMULTANEOUS ESTIMATION OF MOMETASONE FUROATE AND FORMOTEROL FUMARATE BY HPLC METHOD IN ROTACAPS
Authors: Zanwar Aarti S. , Sen Dhanya B. , Sen Ashim Kumar , Seth A. K. 
Published: February 2019

Objective: To develop and validate a simple and sensitive RP-HPLC method for the simultaneous determination of mometasone furoate (MOM) and formoterol fumarate (FOR) in pharmaceutical dosage forms.
Methods: In RP-HPLC method, chromatographic separation was achieved using a mixture of a solvent system consisting of methanol–water (pH 3.5) in the ratio of 85:15 % v/v at a flow rate of 1 ml/min and detection was carried out at 225 nm.
Results: The run time for the simultaneous estimation of drugs for the proposed method was 10 min as drugs eluted at 5.217 min (MOM) and 8.650 min (FOR). The linearity was found in the range of 33.33-299.97 μg/ml and 1-9 μg/ml for MOM and FOR, respectively. The values of limit of detection and limit of quantification were 3.634, 0.266 µg/ml and 11.014, 0.807 µg/ml, which indicates the sensitivity of the method for the estimation of MOM and FOR, respectively. The results of recovery studies for both the drugs were within the range i.e. 98.87-101.48 % which indicates the accuracy of the method. Relative standard deviation obtained from repeatability and reproducibility studies were less than 2% indicates the precision of the method. The proposed method was validated according to ICH guidelines.
Conclusion: The proposed RP-HPLC method was found to be sensitive and precise because of the low LOD, LOQ and % RSD values (<2). The proposed work does not require acetonitrile and ion pairing reagent as compared to the reported methods. Therefore, method can be used preferably for routine analysis due to its simplicity and economic advantages.
EVALUATION OF BACTERICIDAL ACTIVITY OF AN ANTISEPTIC GELTHROUGH THE DILUTION-NEUTRALIZATION METHOD
Authors: Arias-Palacios Janeth Del Carmen , ESQUIVEL LIBARDO HERNANDEZ , Medina Dorelly Sandoval , B. Tatiana Diaz 
Published: February 2019

Objective: To evaluate the bactericidal activity of an antiseptic gel for hygiene and disinfection of the hands by rubbing.
Methods: The dilution-neutralization method was used according to Colombian Technical Standard NTC, 2009, 12, 16 in Instituto Colombiano de Normas Técnicas y Certificación (ICONTEC), 5 strains, over 6 different types and with 6 replicas per time were exposed to the antiseptic gel, using Letheen Broth as a neutralizer substance.
Results: A 99% of reduction was obtained with Staphylococcus aureus 6538, Enterococos hirae 10541, Pseudomonas aeruginosa 15442 and Klebsiella sp, within the first 30 s of exposure to the gel and within the first 60 s of exposure using the Escherichia coli 19538. All strains used coming from American Type Culture Collection (ATCC).
Conclusion: It was confirmed that the product is effective. In presence of a neutralizer substance, the microorganisms were not inhibit, so the growing reduction occurs due to the action of the product.
POLYPHARMACY INDUCED DRUG INTERACTIONS, ADVERSE DRUG REACTIONS (ADR) AND MEDICATION ERRORS IN TERTIARY CARE SOUTH INDIAN HOSPITAL
Authors: R. Siddarama , J. Bharath Naidu , P. Joshisree K. , V. Sahithi Lakshmi 
Published: February 2019

Objective: To study the pattern of drug interactions (DI) in our hospital and to identify whether it is associated with polypharmacy. To determine the level of severity of potential drug-drug interactions (PDDI), to detect, monitor and prevention of ADRs in the hospitalized patients and to identify the medication errors (ME).
Methods: A prospective interventional study was conducted in a 300 bedded tertiary care South Indian hospital for a period of 6 mo. Prescriptions were analysed for PDDI using Micromedex software 2.2. The causality and severity of ADRs were assessed by using Naranjo’s, WHO UMC Scales and Hart wigs severity scales. ME was identified by review of patient drug charts.
Results: Total 190 prescriptions were analyzed, in which 1028 drug interactions were seen. Out of which 718 were DDI, 198 DFI, 100 DEI, and 12 DTI were observed. More number of DI was seen in cardiovascular drugs, antibiotics followed by antacids and antiulcer agents. A total of 52 ADRs were identified in 43 patients. Diuretics, cardiovascular drugs were associated with a higher incidence of ADRs followed by Anti-Diabetic agents. 58 ME was seen in 190 prescriptions, among them omission error, prescribing errors and Wrong dose error was seen.
Conclusion: Clinical pharmacist plays a potential role in the health care system in assisting the physician i.e. modifying the number of drugs taken, number of doses taken, medication adherence, identification of drug interactions, preventing, monitoring and detection of ADRs and identifying the medication errors.
THE BENEFICIAL EFFECT OF 20% SUNFLOWER SEED OIL CREAM ON MILD ATOPIC DERMATITIS IN CHILDREN
Authors: Dwiyana Reiva Farah , Darmadji Hartati Purbo , Hidayah Risa Miliawati Nurul , Hergyana Fitra , Gondokaryono Srie Prihiantini , Diana Inne Arline , Sutantoyo Catherina Jessica , Gunawan Hendra 
Published: February 2019

Objective: The objective of this study was to evaluate the beneficial effect of topical applications of 20% sunflower seed oil (SSO) in decreasing the transepidermal water loss (TEWL) and scoring of atopic dermatitis (SCORAD) index value in mild atopic dermatitis (AD) pediatric patients in Bandung, Indonesia.
Methods: This was a randomized study involving 20 children with mild AD (SCORAD<25) in Bandung, Indonesia. They were divided into 2 groups: the experimental group treated with 20% SSO cream and the control group treated with a common moisturizing cream for four weeks. The TEWL score including SCORAD index was evaluated at baseline, week 1, week 2, and week 4.
Results: A total of 20 participants completed the study. In the first week, the control group had TEWL score decrement by 36.62% while the experimental group by 28.89% (p=0.88). In the fourth week, the TEWL decrements of the experimental and control group were by 56.94% and 52.50%, respectively (p=0.20), and this was followed by an improvement of SCORAD index in both treatment groups.
Conclusion: The 20% SSO cream has a beneficial effect in decreasing the TEWL score and improving SCORAD indices. Therefore, it can be considered as an alternative treatment for mild AD among children.
ESTIMATION OF BACOSIDE-A IN BACOPA MONNIERI AERIAL PARTS USING TLC DENSITOMETRY
Authors: KUMAR RAJESH , SINGH TEJPAL , KUMAR DEEPAK , SINGH MANDEEP , KAUR SANDEEP , GARG RAJEEV 
Published: February 2019

Objective: The objective of the present work was to formulate and evaluate a stable, odour free garlic powder loaded floating matrix tablet for the treatment of peptic ulcers.
Methods: A gastro-retentive floating matrix tablet (FMT) formulation of garlic powder (GP) was prepared using various concentrations of hydroxypropyl methylcellulose K4M (HPMC K4 M) and effervescent system (sodium bicarbonate and citric acid in 1:1 % w/w) to achieve desirable floating time (FT), floating lag time (FLT) and drug release. Wet granulation method was selected using ethanol as a binder for preparation of tablet. 32 full factorial designs were used for selection of suitable polymer concentration and effervescent system. Nonenteric film coating was applied to mask GP odour.
Results: It was observed that FMT with optimum quantities of HPMC K4M and the effervescent system showed 97 % of drug release in 12 h with FT up to 10 h and minimum FLT of 3 min. There was no significant change in FLT, FT and drug content during the stability study of FMT.
Conclusion: A stable, sustained release FMT of GP tablets using HPMC K4M and an effervescent system was successfully prepared. This formulation can overcome problems of taste and odour masking, gastric irritation, and loss of active constituents present in garlic.
A pobreza urbana e a pobreza de direitos no Rio de Janeiro de Vargas | Urban poverty and the poverty of rights in the Rio de Janeiro of the Vargas era
Authors: Barone Ana Cláudia 
Published: February 2019

Resenha do livro de Brodwyn Fischer, A Poverty of Rights, Citizenship and Inequality in Twentyeth-Century Rio de Janeiro, Stanford: Stanford University Press, 2008.
Prevalence, magnitude, and incidence of labial gingival recession with Herbst-multibracket appliance treatment: A retrospective cohort study
Authors: Bock Niko C. , Ruehl Julia , Ruf Sabine 
Published: February 2019

ABSTRACT

Objective:
To assess the prevalence and magnitude of labial gingival recession (LGR) before and after as well as the incidence during Class II:1 Herbst-Multibracket appliance (Herbst-MBA) treatment (Tx) plus retention in a retrospective cohort study.

Materials and Methods:
Records of Class II:1 patients who completed Herbst-MBA Tx (mean pre-Tx age 14.4 years) at Department of Orthodontics, University of Giessen, Giessen, Germany were analyzed. Tx consisted of a Herbst phase (mean 8.1 months) and a subsequent MBA phase (mean 16.1 months). Study casts from before and after Herbst-MBA Tx plus ≥24 months of retention were evaluated.

Results:
A total of 460 pre-Tx and 222 postretention study casts were available (total observation period: 59.2 ± 14.8 months). The overall prevalence for teeth with LGR ≥0.5 mm was 1.1% pre-Tx and 5.3% postretention. The highest prevalence of up to 5.3% (pre-Tx) and 16.4% (postretention) were seen for the lower incisors. Overall, the median magnitude of LGR was 0.0 mm pre-Tx/postretention (mean: 0.05 mm/0.08 mm). Incidence values of 4.0% (all teeth) and 10.0% to 11.4% (lower central incisors) were calculated for LGR ≥0.5 mm.

Conclusions:
The prevalence of LGR ≥0.5 mm increased from, on average, 1.1% to 5.3% during ≈6 years of Herbst-MBA Tx plus retention. The highest incidence was seen in lower incisors (10.0%–11.4%). However, because of the overall mean magnitude of 0.08 mm postretention, the clinical relevance can be considered as insignificant.
Effect of fluoride dentifrices on white spot lesions during orthodontic treatment: A randomized trial
Authors: Kau Chung H. , Wang Jue , Palombini Anna , Abou-Kheir Nadia , Christou Terpsithea 
Published: February 2019

ABSTRACT

Objectives:
To determine the effect of Clinpro 5000, Clinpro Tooth Crème, and MI-Paste Plus on the formation of white spot lesions in patients undergoing orthodontic treatment.

Materials and Methods:
Three prospective groups with 40 patients undergoing orthodontic treatment in each group were evaluated (total recruitment = 120 subjects). The selected product was brushed on for 2 minutes twice daily for 4 months. Subjects were reviewed for 4 months on a monthly basis. The Enamel Decalcification Index (EDI) was used to determine the number of white spot lesions per surface at each visit.

Results:
100 subjects (35 using Clinpro 5000, 32 using Clinpro Tooth Crème, and 33 using MI Paste Plus) completed the study. The data lend strong support for Clinpro 5000 providing superior protection against enamel decalcification when compared to Clinpro Crème, and mixed support when compared to MI Paste Plus.

Conclusions:
The use of Clinpro 5000, Clinpro Crème, and MI paste Plus all have a reduction effect on white spot lesions when compared to studies reported previously. Clinpro 5000 has a marginally better effect than the two other test pastes. The results of this study can be used by clinicians when deciding the effectiveness of using fluoride dentifrice products to prevent white spot lesions in their orthodontic practice (ClinicalTrials.gov ID: NCT03440996).
Environmental Management Practices in Hospitality Establishments in Slow Cities: Akyaka Example
Authors: Farhadi Andarabi Feriyal , Tunç Hassan Azize 
Published: February 2019

It
is easy to see that tendency to environmentally-conscious practices is
gradually increasing all around the world. Tourism sector inherently involves
activities that develop and grow in conjunction with natural environment. As the criteria for Slow Cities are based on
the principles of sustainability, they would provide convenience to carry out
sustainable tourism activities in these cities. This study is aimed at
investigating the current status of accommodation establishments in Cittaslow
Akyaka in Ula county of Muğla province within the scope of environmental management
practices. For this purpose,
face-to-face interviews have been made with executives of 6 accommodation
establishments in Akyaka. As a result of the research, it is determined that
the participants don’t have sufficient knowledge regarding environmental
management practices and their benefits. Another finding of the research is
that the accommodation establishments in Akyaka don’t differ from each other
with regard to their environmentally sensitive practices in terms of their
types. Training programs organized for the executives of accommodation
establishments within the scope of environmental management and practices may
support Akyaka to pursue the path of being sensitive to environment.
Energy Audit of a Wheat Processing Plant in Rivers State, Nigeria
Authors: Green Christian Raymond , Sodiki John I. , Nkoi Barinyima 
Published: February 2019

In this study, energy audit of a wheat processing plant in Rivers State, Nigeria has been carried out. A walked-through energy audit method was undertaken to identify the major sources of energy in use, identify the lapses in energy usage, identify areas to improve energy usage, determine the level of energy consumption of the various energy sources and recommending policy measures that will enhance energy savings in the industry. The analysis showed that eight defined unit operations were required for the production of wheat flour; Truck Loading, Intake or Storage, Cleaning, Tempering or Conditioning, Holding Bin, Milling, Finished Product and Packaging. The types of energy used were electrical, thermal (diesel and gas), and manual energies with proportions of 14.63%, 85.31% and 0.05% respectively of total energy input. Average energy intensity was estimated to be 1.3GJ/tonnes for the production of wheat flour for the 5 years (2011-2015) study period. The most energy intensive operation was identified as the milling process with percentage energy input of 44.39% (123837.60MJ) followed by Finished Product Storage process with percentage energy input of 36.17% (100885.92MJ). It was observed that the industry under review did not sufficiently utilize energy as the energy used ratio is below 1. This was as a result of some factors that contributed to energy waste and energy use inefficiency in the industry. Among these factors are: electric motor that dissipate much heat, use of electric motors that have been rewound more than twice and generation of electricity more than needed in the industry by some generators. The exergy analysis showed that the roller dryer accounted for the major loss in the process with an inefficiency of 44.8%. The useful work was 5.3kJ; exergy loss expended is 15.68kJ in the roller dryer. The study concluded that energy is not sufficiently utilized in the industry resulting in high energy waste and high pricing of wheat flour products.
ANÁLISIS NUMÉRICO DEL PROCESO DE INFILTRACIÓN DE AGUA Y LOCALIZACIÓN DE DEFORMACIÓN EN SUELOS PARCIALMENTE SATURADOS
Authors: Tobón Sánchez Willideman , García Aristizábal Edwin Fabián , Vega Posada Carlos Alberto 
Published: February 2019

En este trabajo se presentan simulaciones del proceso de infiltración de agua en suelos parcialmente saturados en una y en dos dimensiones, haciendo uso de un método acoplado infiltración-deformación. El estudio de la infiltraciónunidimensional se realizó en dos partes: primero, considerando un suelo homogéneo y posteriormente, un suelo estratificado compuesto de dos horizontes diferentes. Para ambos casos se modelaron columnas unidimensionales de un metro de espesor, con las que se realizó un estudio paramétrico tomando diferentes valores de Intensidad de lluvia. Del análisisse encontró que el fenómeno de infiltración unidimensional tiene una alta dependencia de la relación intensidad de lluvia (I)/Permeabilidad del suelo (ksW) y en el caso de los suelos estratificados se evidenció un control de la infiltración por parte del suelo de menor permeabilidad. Finalmente, se analizó el caso de infiltración bidimensional mediante la modelación de un talud sometido a lluvia de alta intensidad donde se pudo localizar la superficie de falla en el talud. Los resultados de este análisis muestran el potencial de esta metodología para el estudio de estructuras de suelo sometidas a procesos de infiltración.