bluuebunny/crossref_metadata_2025_split huggingface dataset:
In‐hospital opioid consumption, but not pain intensity scores, predicts 6‐month levels of pain catastrophizing following hepatic resection: A trajectory analysis
Authors: Pagé M. Gabrielle , Karanicolas Paul J. , Cleary Sean , Wei Alice C. , McHardy Paul , Ladak Salima S. J. , Ayach Nour , Sawyer Jason , McCluskey Stuart A. , Srinivas Coimbatore , Katz Joel , Coburn Natalie , Hallet Julie , Law Calvin , Greig Paul , Clarke Hance 
Published: October 2018

AbstractBackgroundThe study aims were to model acute pain intensity and opioid consumption trajectories up to 72 hr after open hepatic resection, identify predictors of trajectory membership and examine the association between trajectory memberships and 6‐month pain and psychological outcomes. This is a long‐term analysis of a published randomized controlled trial on the impact of medial open transversus abdominis plane catheters on post‐operative outcomes.MethodsA total of 152 patients (89 males; mean age 63.0 [range: 54–72]) completed questionnaires on pain and related characteristics pre‐operatively and 6 months post‐operatively. Total opioid use was recorded several times over a 72‐hr period while self‐reported pain intensity scores were collected multiple times until hospital discharge. Analyses were carried out using growth mixture modelling, logistic regression and general linear models.ResultsBoth pain intensity and opioid consumption showed that a four‐trajectory model best fits the data. Patients in the lowest opioid consumption trajectory were more likely to be classified in the constant mild pain intensity trajectory. Age and baseline levels of anxiety significantly predicted opioid trajectory membership while baseline depressive symptoms significantly predicted pain intensity trajectory membership. Patients in the two highest opioid consumption trajectories reported significantly higher levels of pain catastrophizing at 6 months compared to patients in the other 3 trajectories (all p < 0.05).ConclusionHigh consumption of opioids after surgery is associated with higher levels of pain catastrophizing 6 months later. Identification of patients within these trajectories may lead to the development of early interventions targeted to high risk individuals.SignificanceDifferences in initial levels of opioid consumption and rates of change in opioid consumption shortly after surgery can help predict long‐term psychological responses to pain. Identifying key characteristics associated with initial opioid consumption can lead to the development of cost‐effective early interventions targeted to high risk individuals.
Copper toxicity in Bristol Bay headwaters: Part 2—Olfactory inhibition in low-hardness water
Authors: Morris Jeffrey M. , Brinkman Stephen F. , Takeshita Ryan , McFadden Andrew K. , Carney Michael W. , Lipton Joshua 
Published: October 2018

Abstract

We investigated the olfactory toxicity of copper (Cu) to rainbow trout in low-hardness (27 mg/L as CaCO3) water formulated in the laboratory over a 120-h period using a flow-through design. The fish's response to an alarm cue (e.g., reduction in activity) was recorded to determine the exposure concentrations and durations that inhibited olfactory detection of the cue after 3, 24, 48, and 96 h of Cu exposure and after 24 h of clean water recovery following the 96-h exposure period. Exposures were conducted with a range of Cu concentrations from 0.13 (control) to 7.14 μg Cu/L (dissolved Cu). We observed a dose-dependent response in olfactory inhibition with a 20% reduction in the probability of responding to the alarm cue, relative to controls, at 2.7 and 2.4 μg Cu/L after 24 or 96 h of exposure, respectively. Olfactory inhibition manifested between 3 and 24 h of exposure. Our 24- and 96-h 20% olfactory inhibition estimates fell between the criteria derived using the biotic ligand model (BLM; criterion maximum concentration [CMC] and criterion continuous concentration [CCC] values were 0.63 and 0.39 μg Cu/L, respectively) and water hardness–based criteria (CMC and CCC values were 3.9 and 2.9 μg Cu/L, respectively). Therefore, the hardness-based criteria do not appear to be protective and the BLM-derived criteria do appear to be protective against Cu-induced olfactory inhibition given our test water chemistry. Neither the hardness-based criteria nor the BLM-derived criteria appear to be protective against our estimated Cu behavioral avoidance response concentrations at 24- and 96-h exposures (0.54 and 0.50 μg Cu/L, respectively). Environ Toxicol Chem 2019;38:198–209. © 2018 SETAC
A 21.6 kDa tegumental protein of Clonorchis sinensis induces a Th1/Th2 mixed immune response in mice
Authors: Chung EunJoo , Kim Yu Jung , Lee Myoung‐Ro , Cho Shin‐Hyeong , Ju Jung‐Won 
Published: October 2018

AbstractIntroductionClonorchis sinensis is a major parasite affecting the Korea population. Despite the high infection rate and pathogenicity, very few studies have been conducted to investigate the immune responses against the proteins of C. sinensis.MethodsIn this study, in vitro immune response induced by a recombinant 21.6 kDa tegumental protein derived from C. sinensis (rCsTegu21.6) was confirmed in murine dendritic cells and T cells. For the in vivo analysis, each mouse was immunized three times. Total serum IgG and T cell cytokine production were determined by ELISA, while T cell proliferation was detected by a WST (Water‐Soluble Tetrazolium salt)‐1 assay.ResultsIn vitro tests indicated that rCsTegu21.6 treatment increased the expression of surface molecules, such as CD40 (77%), CD80 (52%) and CD86 (46%), on murine dendritic cells and the secretion of cytokines (TNF‐α, IL‐6, IL‐1β, IL‐10, and IL‐12p70). Moreover, co‐culturing dendritic cells activated by rCsTegu21.6 with allogenic T cells induced T cell proliferation over time. rCsTegu21.6 also stimulated specific antibody production and cytokine secretion [IL‐2, IL‐4, and interferon (IFN)‐γ)] from T cells following immunization in vivo. Notably, rCsTegu21.6 predominantly induced IgG1 production and secretion of the Th2 cytokine IL‐4, regardless of the type of adjuvant used.ConclusionThese results serve as a foundation for the development of tegumental protein‐based vaccines against C. sinensis.
Assessing the Capacity of Hispanic Serving Institutions to Serve Latinx Students: Moving Beyond Compositional Diversity
Authors: Franco Marla A. , Hernández Susana 
Published: October 2018

AbstractThis chapter provides an overview of the growth among Hispanic serving institutions (HSIs) and discusses the use of assessment as a key strategy for understanding institutional capacity for serving Latinx college students. Frameworks for understanding campus climate and examining college outcomes among Latinx students are explored, along with highlighting models for assessing campus climate and the practical implications for doing so. This chapter suggests that through the use of well‐established frameworks for understanding campus climate, IR should provide leadership in identifying the information needs of HSIs and emerging HSIs to enable broadened understanding and informed decision support to best serve Latinx college students.
Teaching Assessment: Preparing our Colleagues Through Graduate Education
Authors: Ballysingh Tracy Arámbula , Hernández Ignacio , Zerquera Desiree 
Published: October 2018

AbstractThis chapter provides a framework for grounding social justice principles at the center of learning in higher education program assessment and evaluation courses. Pedagogical reflections are drawn from the classroom experiences of three faculty of color who represent diverse institutional, programmatic, and geographic contexts. Their advanced framework incorporates theories of experiential learning, critical pedagogy, and problems of practice. It further explains how these notions might converge to foster a social justice‐centered approach to graduate instruction of assessment and evaluation for higher education and student affairs. The authors incorporate excerpts from course syllabi and lesson plans to demonstrate how this framework better integrates social justice principles with the practice of assessment; two concepts commonly treated as separate pedagogical entities. This chapter will inform faculty in higher education and student affairs graduate programs, institutional researchers, and practitioners committed to advancing assessment practices that embrace social justice as a core value in higher education.
Experimental and numerical investigations for optimal emitter spacing in drip irrigation
Authors: Ghumman Abdul Razzaq , Iqbal Muhammad , Ahmed Sajjad , Hashmi Hashim Nisar 
Published: October 2018

AbstractWith the goal of determining optimal emitter spacing in drip irrigation, experiments were performed to examine the effects of emitter discharge on the wetted perimeter and spacing of emitters. Four types of soils were investigated using emitter discharge of 1.0, 2.0, 3.0 and 4.0 l h−1. Wetting diameter was measured at six equal time intervals of water application. An equal volume of water was applied. After 1 h of supply of water, wetted soil was cut to observe the maximum wetted width and depth. Wet soil samples were taken from every patch of 10 × 10 cm to find the percentage of moisture by the gravimetric method. Empirical equations were developed for wetted depth and radius. Additional experiments with emitter discharge of 1–18 l h−1 were performed in sandy loam to obtain more data for accurate estimation of the coefficients of the empirical equations. Two computer programs based on trial and error and the generalized reduced‐gradient non‐linear‐optimized technique were used to find values of the coefficients. Root mean square error between the measured and simulated wetted radius and depth was minimized in optimization. Optimal emitter spacing for each type of soil was determined from the recorded data, which was found to be 35, 40, 40 and 45 cm in sandy loam, loam, clayey loam and clay respectively. © 2018 John Wiley & Sons, Ltd.
Evaluation of a new matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry system for the identification of yeast isolation
Authors: Lee Hyeyoung , Park Ji‐Hyun , Oh Junsang , Cho Sungil , Koo Jehyun , Park Ik Chun , Kim Jiwoo , Park Sehyun , Choi Ji Seon , Shin So Youn , Sung Gi‐Ho , Kim Jayoung 
Published: October 2018

BackgroundCurrently, three commercial in vitro diagnostic matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry (MALDI‐TOF MS) systems are widely used in clinical laboratories. The ASTA MicroIDSys system (ASTA Inc, South Korea) is a newly developed MALDI‐TOF MS system used for the identification of pathogenic microorganisms. In the present study, we assessed the performance of the ASTA MALDI‐TOF MS system for the identification of pathogenic yeast from clinical samples.MethodsWe tested 284 clinical yeast isolates from various clinical specimens using ASTA MALDI‐TOF MS, and the results were compared with those using molecular sequencing of the ITS or D1‐D2 regions of rDNA and biochemical assays.ResultsA total of 284 isolates were tested and found to be distributed across 14 species including Candida albicans (n = 100) and other yeast species (n = 184). ASTA MALDI‐TOF MS correctly identified 95.1% (270/284) of the yeast species compared to molecular sequencing. Among them, 262 isolates showed acceptable MALDI‐TOF MS scores (≥140), and 98.1% (257/262) isolates were identified correctly. In addition, among 22 isolates with a MALDI‐TOF MS score <140, 59.1% (13/22) of the isolates showed concordance with molecular typing at the species level. Clustering analysis revealed the effectiveness of the new MALDI‐TOF MS system for the identification of yeast species.ConclusionsASTA MALDI‐TOF MS showed high accuracy in the identification of yeast species; it involves facile sample preparation and extraction procedures. ASTA MALDI‐TOF MS is expected to be useful for yeast identification in clinical microbiology laboratories due to its reliability and cost‐effectiveness.
Starmerella bombicola: recent advances on sophorolipid production and prospects of waste stream utilization
Authors: Wang Huaimin , Roelants Sophie LKW , To Ming H , Patria Raffel D , Kaur Guneet , Lau Ngai S , Lau Chun Y , Van Bogaert Inge NA , Soetaert Wim , Lin Carol SK 
Published: October 2018

AbstractSophorolipids are among the most extensively studied microbial biosurfactants. Starmerella bombicola is the most productive strain known for sophorolipid production, with volumetric productivity of up to 3.7 g L−1 h−1. This review focuses on the two most important aspects that have an influence on sophorolipid commercialization. Firstly, the metabolic engineering achievements of S. bombicola in the last decade are summarized. Secondly, three improvements of the bioprocess are described, including alternative feedstock, fermentation strategy and specially designed bioreactor. Discussion is made on the waste sources that have been used as feedstock for sophorolipid production, and the review also emphasizes the potential of food waste as nutrient source. Fermentation strategies that correlate with the specially designed bioreactors for commercialization are also discussed in detail. © 2018 Society of Chemical Industry
Analysis of volatile components in Dalbergia cochinchinensis Pierre by a comprehensive two‐dimensional gas chromatography with mass spectrometry method using a solid‐state modulator
Authors: Xiang Zhangmin , Chen Xiaotian , Zhao Zhijun , Xiao Xue , Guo Pengran , Song Huacan , Yang Xi , Huang Minghua 
Published: October 2018

AbstractVolatile components in Dalbergia cochinchinensis Pierre were analysed using a comprehensive two‐dimensional gas chromatography with mass spectrometry method featuring a new solid‐state modulator. Compared to one‐dimensional gas chromatography, the number of detected peaks were significantly increased. A total of 45 major compounds were identified in this study and the forward and reverse match factors of these compounds were both above 800. The results showed that the volatile components in Dalbergia cochinchinensis Pierre were primarily aldehyde and ketone compounds such as benzaldehyde, cinnamaldehyde, 4‐chromanone, 1‐(2‐hydroxyphenyl)ethanone and acetophenone. In addition, a semi‐quantitative analysis was conducted to determine the contents of the detected compounds based on peak area percentage. Moreover, the repeatability of the comprehensive two‐dimensional gas chromatography‐mass spectrometry analysis in this study was quite satisfactory with relative standard deviations less than 12.7% for intraday and 17.3% for interday measurements.
Oligo(thioether‐ester)s Blocks in Polyurethanes for Slowly Releasing Active Payloads
Authors: Klahan Butsabarat , Seidi Farzad , Crespy Daniel 
Published: October 2018

AbstractThe preparation of acid‐responsive degradable oligomers with active agents in their main chains is described. Dichlorophene (DCP), an effective anticestodal agent, and the corrosion inhibitor 4‐(2‐pyridylazo)resorcinol (PAR) are reacted to form polymerizable bisacrylate derivatives. The derivatives are then copolymerized with aliphatic and aromatic dithiols by thiol‐Michael addition to obtain a polymer backbone with cleavable thiopropionate groups. Low molecular weight (M
n < 10 000 g mol−1) linear oligomers are obtained, which can be used for the preparation of poly(ester‐urethane)s. Polymer nanoparticles from both oligo(thioether‐ester) and poly(ester‐urethane)s are fabricated by the miniemulsion‐solvent evaporation method. The polymers in solution and dispersion can be gradually degraded in acidic media. The degraded products of the degradation of PAR containing polymers can be detected in the presence of copper ions.
Investigation on the Thermal Degradation Kinetics of Polypropylene/Organically Modified Montmorillonite Nanocomposites with Different Levels of Compatibilizer
Authors: Vimalathithan Paramsamy Kannan , Barile Claudia , Casavola Caterina , Vijayakumar Chinnaswamy Thangavel , Arunachalam Sundaresan , Battisti Markus Gottfried , Friesenbichler Walter 
Published: October 2018

AbstractPolypropylene/organically modified montmorillonite (OMMT) nanocomposites are prepared with different levels of compatibilizer (maleic anhydride functionalized polypropylene) and OMMT. A specially designed polymer nanocomposite injection molding compounder with a hyperbolic nozzle is used to prepare the nanocomposites. The thermal kinetic parameters, the activation energy, pre‐exponential factor, and the reaction model are estimated using isoconversional methods. The activation energy of virgin polypropylene is slightly higher than the polypropylene/OMMT nanocomposites. However, the presence of the compatibilizer is the vital reason for the lower activation energy in the polypropylene/OMMT nanocomposites. The reaction model explains the complexity of the reaction in the presence of OMMT and its influence on the accelerated charring in the later stages of degradation. The optimum working temperature of the prepared polypropylene/clay nanocomposites is significantly higher thus proving that OMMT improves the thermal stability of the nanocomposites. The polypropylene with 5% OMMT and 10% compatibilizer in its weight proportion has the optimum working temperature of 198 °C for 20 000 h before losing its integrity.
W361R mutation in GaaR, the regulator of D‐galacturonic acid‐responsive genes, leads to constitutive production of pectinases in Aspergillus niger
Authors: Alazi Ebru , Niu Jing , Otto Simon B. , Arentshorst Mark , Pham Thi T. M. , Tsang Adrian , Ram Arthur F. J. 
Published: October 2018

AbstractPolysaccharides present in plant biomass, such as pectin, are the main carbon source for filamentous fungi. Aspergillus niger naturally secretes pectinases to degrade pectin and utilize the released monomers, mainly D‐galacturonic acid. The transcriptional activator GaaR, the repressor of D‐galacturonic acid utilization GaaX, and the physiological inducer 2‐keto‐3‐deoxy‐L‐galactonate play important roles in the transcriptional regulation of D‐galacturonic acid‐responsive genes, which include the genes encoding pectinases. In this study, we described the mutations found in gaaX and gaaR that enabled constitutive (i.e., inducer‐independent) expression of pectinases by A. niger. Using promoter‐reporter strains (PpgaX‐amdS) and polygalacturonic acid plate assays, we showed that W361R mutation in GaaR results in constitutive production of pectinases. Analysis of subcellular localization of C‐terminally eGFP‐tagged GaaR/GaaRW361R revealed important differences in nuclear accumulation of N‐ versus C‐terminally eGFP‐tagged GaaR.
AMS‐800 Artificial urinary sphincter in female patients with stress urinary incontinence: A systematic review
Authors: Peyronnet Benoit , O'Connor Eabhann , Khavari Rose , Capon Grégoire , Manunta Andrea , Allue Marta , Hascoet Juliette , Nitti Victor W. , Gamé Xavier , Gilleran Jason , Castro‐Sader Luis , Cornu Jean‐Nicolas , Waltregny David , Ahyai Sascha , Chung Eric , Elliott Daniel S. , Fournier Georges , Brucker Benjamin M. 
Published: October 2018

AimsTo perform a systematic review of studies reporting the outcomes of AMS‐800 artificial urinary sphincter (AUS) implantation in female patients with stress urinary incontinence (SUI) resulting from intrinsic sphincter deficiency (ISD).MethodsA systematic literature search of the Medline and Embase databases was performed in June 2018 in accordance with the PRISMA statement. No time limit was used. The protocol was registered in PROSPERO (CRD42018099612). Study selection and data extraction were performed by two independent reviewers.ResultsOf 886 records screened, 17 were included. All were retrospective or prospective non‐comparative case series. One study reported on vaginal AUS implantation, 11 on open AUS implantation, two on laparoscopic AUS implantation, two on robot‐assisted AUS implantation and one compared open and robot‐assisted implantations. The vast majority of patients had undergone at least one anti‐incontinence surgical procedure prior to AUS implantation (69.1‐100%). The intraoperative bladder neck injury rates ranged from 0% to 43.8% and the intraoperative vaginal injury rates ranged from 0 to 25%. After mean follow‐up periods ranging from 5 to 204 months, the complete continence rates ranged from 61.1% to 100%. The rates of explantation, erosion and mechanical failure varied from 0% to 45.3%, 0% to 22.2% and 0% to 44.1%, respectively.ConclusionsAMS‐800 AUS can provide excellent functional outcomes in female patients with SUI resulting from ISD but at the cost of a relatively high morbidity. High level of evidence studies are needed to help better define the role of AUS in the female SUI armamentarium.
Beyond white‐tailed deer hunting in Aguazuque: Archaeofaunal data from an archaic site at Sabana de Bogotá, Colombia
Authors: Martínez‐Polanco María Fernanda 
Published: October 2018

AbstractIt is assumed that the hunter‐gatherers of the Sabana de Bogotá focused their subsistence strategies on white‐tailed deer (Odocoileus virginianus) hunting. The deer was their main prey because it was one of the largest animals in the area. However, there are differences between the early, middle, and late Holocene hunter‐gatherers in terms of their ways of life. The aim of this article is to contribute to a better understanding of animal resource exploitation and management particularly of white‐tailed deer using archaeofaunal remains from Aguazuque site at the Sabana de Bogotá, Colombia dated between 5,025 ± 40 BP (3,925–3,770 cal BP) and 2,725 ± 35 BP (900–825 cal BP). This is a key site for understanding social change in the middle and late Holocene at the Sabana de Bogotá. To describe the faunal set, two indexes were used: number of identified specimens and minimal number of individuals. Contra to models proposing the specialised hunting of big game for hunter‐gatherers in this region, the inhabitants of Aguazuque did not exclusively focus their diet on white‐tailed deer hunting; they used other animal species, such as guinea pigs, and plants played an important role in the human diet of Aguazuque.
Horse riding and the shape of the acetabulum: Insights from the bioarchaeological analysis of early Hungarian mounted archers (10th century)
Authors: Berthon William , Tihanyi Balázs , Kis Luca , Révész László , Coqueugniot Hélène , Dutour Olivier , Pálfi György 
Published: October 2018

AbstractHorse riding is a human activity that has particularly interested bioanthropologists and paleopathologists working on the reconstruction of activities from skeletal changes in ancient populations. However, various sample and methodological limitations, such as the absence of direct evidence connecting the individuals and the activity, result in a lack of confidence regarding what changes should be included in the so‐called horse riding syndrome. Focusing on the ovalization of the acetabulum, regularly mentioned in literature, we analyzed comparative samples of presumed riders and non‐riders to evaluate its reliability for the identification of horse riding.We relied on a Hungarian Conquest period collection (10th century CE), including several individuals associated with horse riding equipment or horse bones in the graves. Direct and easily repeatable measurements were used to calculate an index of ovalization of the acetabulum (IOA). The index values were compared according to the presence or absence of archaeological deposit. An extra‐group of presumed non‐riders from the documented Luís Lopes Skeletal Collection (Lisbon) was used for comparison.Early Hungarians buried with horse‐related grave goods exhibited a higher overall IOA compared with the ones without and those known not to ride (p = 0.049 in the latter case, with left and right values combined).Our results suggest that the ovalization of the acetabulum may indeed be a promising indicator to be included in a set of markers for horse riding. The analysis of further different types of pathological and nonpathological skeletal changes (e.g., joint and entheseal changes) will contribute to a more reliable identification of horse riders in anthropological collections.