bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Estimation Method of Metal‐Ligand Orbital Mixing in Lanthanide(III) Complexes Using Magnetic Circular Dichroism
Authors: Kitagawa Yuichi , Nakanishi Takayuki , Fushimi Koji , Hasegawa Yasuchika 
Published: March 2018

AbstractThe photophysical properties of lanthanide(III) complexes depend on the magnitude of orbital mixing between the lanthanide(III) and ligands. Herein, an estimation method of orbital mixing in lanthanide(III) complexes is reported using LnCl3⋅nH2O (Ln=Pr, Gd, Tb) and Ln(tfa)3(H2O)2 (tfa: trifluoroacetylacetonate, Ln=Pr, Gd, and Tb) for the first time. The electronic state properties were assessed from the electronic absorption and magnetic circular dichroism (MCD) spectra. The MCD spectra revealed the energy levels of the spin‐allowed and spin‐forbidden 4 f–5d transitions of the Tb(III) complex that is hidden by the intense π–π* transition of the ligands. This energy gap corresponds to the exchange splitting energy between the 5d and 4fn−1 electrons, which provides information regarding the orbital mixing between the Tb(III) ion and the ligands.
Demand‐side strategy, relational advantage, and partner‐driven corporate scope: The case for client‐led diversification
Authors: Mawdsley John K. , Somaya Deepak 
Published: March 2018

Research Summary: We advance research on corporate diversification by joining insights from the demand‐side and relational views in strategy to offer a novel theory of client‐led diversification. We propose that client‐led diversification results from a combination of the customer‐driven opportunities emphasized in the demand‐side view and the creation of added value through relational assets that is a central tenet of the relational view. Furthermore, we hypothesize that suppliers’ client‐specific knowledge, clients’ relational commitment to suppliers, and growth opportunities in clients’ markets (relative to the suppliers’ own markets) will magnify the client‐led diversification effect. We test our hypotheses using a longitudinal dataset on patent law firms and their diversification into new domains of patent prosecution work for their corporate clients.Managerial Summary: Explanations of why firms diversify into new lines of business have largely concerned the redeployment of underutilized resources, with little regard to opportunities or influences stemming from firms’ existing customers. In our article, we show how the changing scope of business needs from a knowledge‐based supplier firm's set of existing clients is a central driver of supplier‐firm diversification, and this is especially the case when the level of relational assets shared between a supplier and its clients is higher. In a competitive landscape where suppliers compete intensively for the business of clients, our results show how managers can increase the likelihood of capturing additional business from its existing exchange relationships rather than bearing the risks of seeking new exchange relationships.
China's first road‐cum‐railway suspension bridge with rigid‐cables of three main stiffening frames in parallel: The two‐storey Jinan Yellow River Bridge
Authors: Wu Xun , Wang Wenzhao , Chen Weizhen , Ding Shihong 
Published: March 2018

AbstractThe Jinan Yellow River Bridge is China's first road‐cum‐railway bridge with rigid‐cables of three main stiffening frames in parallel. The main bridge, which is 796 m long, is a continuous two‐storey steel truss girder with a span arrangement of 128 m + 3 × 180 m + 128 m. The Jinan Yellow River Bridge was designed by China Railway Design Corporation and constructed by Steel Structure Construction Co. Ltd of China Tiesiju Civil Engineering Group.
Allgemeines Nachweiskonzept stabilitätsgefährdeter Bauteile – Normenvorschlag für EN 1993‐1‐5 als neuer Anhang F
Authors: Maur Jörn , Grunert Bernd 
Published: March 2018

AbstractEine überarbeitete Version des Eurocodes 3 für das Plattenbeulen soll bald veröffentlicht werden, in welcher unter anderem die Methode der reduzierten Spannungen in EN 1993‐1‐5 Abschnitt 10 revidiert sein wird. Die hierzu jüngst in dieser Fachzeitschrift publizierten neuen Regelungen, insbesondere zum biaxial gedrückten ausgesteiften Plattenbeulfeld, sind teilweise aufwendig. Ergänzend zu diesen bekanntgemachten Regeln wird im Normenvorschlag ein Konzept der „stufenweisen Genauigkeit” angewendet, mit welchem sich ein unterer Grenzwert des Beulwiderstandes schnell ermitteln lässt. Für den Nachweis der Beulsteife wird basierend auf einem bereits veröffentlichten Vorschlag (Vorverformungsamplitude als geometrische Ersatzimperfektion für den Steifennachweis), ein eigener Abminderungsfaktor für Beulsteifen neu definiert. Wegen der Kompatibilität zum MNA/LBA‐Nachweiskonzept für Schalen in EN 1993‐1‐6 wird eine normenteilübergreifende Formulierung vorgeschlagen, die eine allgemeine Betrachtung zusammengesetzter stählerner Strukturen zukünftig normativ regeln kann. Der Normenvorschlag wird anhand von Beispielen veranschaulicht.
Intron retention in viruses and cellular genes: Detention, border controls and passports
Authors: Rekosh David , Hammarskjold Marie‐Louise 
Published: March 2018

Intron retention (IR), where one or more introns remain in the RNA after splicing, was long thought to be rare in mammalian cells, albeit common in plants and some viruses. Largely due to the development of better methods for RNA analysis, it has now been recognized that IR is much more common than previously thought and that this mechanism is likely to play an important role in mammalian gene regulation. To date, most publications and reviews about IR have described the resulting mRNAs as “dead end” products, with no direct consequence for the proteome. However, there are also many reports of mRNAs with retained introns giving rise to alternative protein isoforms. Although this was originally revealed in viral systems, there are now numerous examples of bona fide cellular proteins that are translated from mRNAs with retained introns. These new isoforms have sometimes been shown to have important regulatory functions. In this review, we highlight recent developments in this area and the research on viruses that led the way to the realization of the many ways in which mRNAs with retained introns can be regulated.This article is categorized under:

RNA Processing > Splicing Mechanisms
RNA Processing > Splicing Regulation/Alternative Splicing
RNA Export and Localization > Nuclear Export/Import
RNA Interactions with Proteins and Other Molecules > RNA–Protein Complexes
Asymptotic behavior of a 2D overhead crane with input delays in the boundary control
Authors: Al‐Musallam Fadhel , Ammari Kaïs , Chentouf Boumediène 
Published: March 2018

AbstractThe paper investigates the asymptotic behavior of a 2D overhead crane with input delays in the boundary control. A linear boundary control is proposed. The main feature of such a control lies in the fact that it solely depends on the velocity but under the presence of time‐delays. We end‐up with a closed‐loop system where no displacement term is involved. It is shown that the problem is well‐posed in the sense of semigroups theory. LaSalle's invariance principle is invoked in order to establish the asymptotic convergence for the solutions of the system to a stationary position which depends on the initial data. Using a resolvent method, it is proved that the convergence is indeed of polynomial type as long as the delay term satisfies a smallness condition. Lastly, non‐convergence results are put forward in the case when such a condition on the delay term is not fulfilled.
Allogenic succession of Korean fir (Abies koreana Wils.) forests in different climate condition
Authors: Lim Chi Hong , An Ji Hong , Jung Song Hie , Lee Chang Seok 
Published: March 2018

AbstractThis study was conducted to clarify the changes in vegetation that occurred due to changing environmental factors, especially climate, at Korean fir (Abies koreana) stands with different climatic conditions established on Mt. Halla, which is located on a southern island of South Korea. The difference of species composition between sites was large and depended on elevation and slope aspect at lower elevations, whereas not as much among stands or between sites at the highest elevations of each slope aspect. It was interpreted that differences and similarities among sites were dominated by the microclimate determined by the topographic conditions of each site. The result of vegetation dynamics analysis predicted that the Korean fir forests would be replaced by temperate forests such as Mongolian oak (Quercus mongolica) forests or shade intolerant forests composed of early successional species such as Korean cherry (Prunus maximowiczii) and Spreading yew (Taxus cuspidata) at lower elevations, while would continuously persist at the highest elevations. We interpreted the vegetation changes appeared at the lower elevations as an allogenic succession, as the recent rapid climate changes directly and indirectly dominated the change. The species distribution modeling predicted that the distributional range of Korean fir would decrease to 13.4 and 10.1% of the current distribution in 2050 and 2070, respectively. Further, the distribution modeling showed that the sites located at lower elevations would no longer be within the distributional range of Korean fir forest, and those at the highest elevations would be sparsely scattered in fragmented states.
Socioeconomic disadvantage and psychological deficits: Pathways from early cumulative risk to late‐adolescent criminal conviction
Authors: Savolainen Jukka , Eisman Andria , Mason W. Alex , Schwartz Joseph A. , Miettunen Jouko , Järvelin Marjo‐Riitta 
Published: March 2018

ABSTRACTEarly exposure to multiple risk factors has been shown to predict criminal offending, but the mechanisms responsible for this association are poorly understood. Integrating social‐environmental and dispositional theories of crime this research investigated the capacity of family socioeconomic disadvantage and individual psychological deficits to mediate the association between childhood cumulative risk and late adolescent criminal convictions. Male participants in the 1986 Northern Finland Birth Cohort Study (n = 3414) were followed from the prenatal period through age 19–20. The data were analyzed by estimating a structural equation model of the hypothesized pathways. The results found support for both processes of influence, and the model sustained a statistically significant direct effect of cumulative risk on crime. Socioeconomic disadvantage and psychological deficits contribute to criminal offending independently and with roughly equal magnitude. The results point to the utility of both environmental and psychological interventions to prevent criminality among children at risk.
Nonsuicidal self‐injury in community adolescents: A systematic review of prospective predictors, mediators and moderators
Authors: Valencia‐Agudo Fatima , Burcher Georgina Corbet , Ezpeleta Lourdes , Kramer Tami 
Published: March 2018

ABSTRACTNonsuicidal self‐injury (NSSI) usually starts during adolescence and is associated with an array of psychological and psychiatric symptoms and future suicide attempts. The aim of this study is to determine prospective predictors, mediators and moderators of NSSI in adolescent community samples in order to target prevention and treatment strategies. Two team members searched online databases independently. Thirty‐nine studies were included in the review. Several variables were seen to prospectively predict NSSI: female gender, family‐related variables, peer victimisation, depression, previous NSSI and self‐concept. Few studies analysed mediators and moderators. Low self‐concept was highlighted as a relevant moderator in the relationship between intra/interpersonal variables and NSSI. Implications of these findings are discussed. The considerable heterogeneity between studies posed a limitation to determine robust predictors of NSSI. Further prospective studies using standardised measures of predictors and outcomes are needed to ascertain the most at risk individuals and develop prevention strategies.
Health-Related Lifestyle Factors and Sexual Dysfunction: A Meta-Analysis of Population-Based Research
Authors: Allen Mark S. , Walter Emma E. 
Published: March 2018

Abstract

Background
Sexual dysfunction is a common problem among men and women and is associated with negative individual functioning, relationship difficulties, and lower quality of life.

Aim
To determine the magnitude of associations between 6 health-related lifestyle factors (cigarette smoking, alcohol intake, physical activity, diet, caffeine, and cannabis use) and 3 common sexual dysfunctions (erectile dysfunction, premature ejaculation, and female sexual dysfunction).

Methods
A comprehensive literature search of 10 electronic databases identified 89 studies that met the inclusion criteria (452 effect sizes; N = 348,865). Pooled mean effects (for univariate, age-adjusted, and multivariable-adjusted estimates) were computed using inverse-variance weighted random-effects meta-analysis and moderation by study and population characteristics were tested using random-effects meta-regression.

Results
Mean effect sizes from 92 separate meta-analyses provided evidence that health-related lifestyle factors are important for sexual dysfunction. Cigarette smoking (past and current), alcohol intake, and physical activity had dose-dependent associations with erectile dysfunction. Risk of erectile dysfunction increased with greater cigarette smoking and decreased with greater physical activity. Alcohol had a curvilinear association such that moderate intake was associated with a lower risk of erectile dysfunction. Participation in physical activity was associated with a lower risk of female sexual dysfunction. There was some evidence that a healthy diet was related to a lower risk of erectile dysfunction and female sexual dysfunction, and caffeine intake was unrelated to erectile dysfunction. Publication bias appeared minimal and findings were similar for clinical and non-clinical samples.

Clinical Translation
Modification of lifestyle factors would appear to be a useful low-risk approach to decreasing the risk of erectile dysfunction and female sexual dysfunction.

Strengths and Limitations
Strengths include the testing of age-adjusted and multivariable-adjusted models and tests of potential moderators using meta-regression. Limitations include low statistical power in models testing diet, caffeine, and cannabis use as risk factors.

Conclusion
Results provide compelling evidence that cigarette smoking, alcohol, and physical activity are important for sexual dysfunction. Insufficient research was available to draw conclusions regarding risk factors for premature ejaculation or for cannabis use as a risk factor. These findings should be of interest to clinicians treating men and women with complaints relating to symptoms of sexual dysfunction.
Effects of Ginkgo Biloba Extract on A53T α-Synuclein Transgenic Mouse Models of Parkinson’s Disease
Authors: Kuang Shaosong , Yang Lin , Rao Ziliang , Zhong Zhiyong , Li Jinfeng , Zhong Haichao , Dai Lulu , Tang Xiaojiang 
Published: March 2018

AbstractBackground: Parkinson’s disease (PD) is a degenerative disorder of the central nervous system mainly affecting the motor system. Presently, there is no effective and safe drug to treat patients with PD. Ginkgo biloba extract (GBE), obtained from leaves of the Ginkgo biloba tree, is a complex mixture of ingredients primarily containing two active components: flavonoids and terpenoids. In this study, we investigated the effects of GBE on A53T α-synuclein transgenic mice, a PD model that has better simulated the progression of PD patients than other models such as the 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine–induced PD model. Methods: Fifty α-synuclein A53T transgenic mice were fed and treated with GBE, and locomotor activity was detected by pole test, forced swim test, and wire-hang test. The expression of tyrosine hydroxylase and dopamine transporters was detected using immunohistochemistry. Superoxide dismutase activity, glutathione peroxidase activity, and malondialdehyde expression were detected using an assay kit. Results: Our results show that GBE treatment improved locomotor activity and that superoxide dismutase and glutathione peroxidase inhibited the expression of methane dicarboxylic aldehyde and recovered the expression of tyrosine hydroxylase and dopamine transporters. Conclusions: The GBE treatment improved locomotor activity and inhibited the development of PD in the A53T α-synuclein transgenic mice, which may be partly responsible for decreased oxidative damage and maintain the normal dopamine homeostasis.
Secondary Abnormal CSF Neurotransmitter Metabolite Profiles in a Pediatric Tertiary Care Centre
Authors: van Karnebeek Clara D.M. , Dunbar Mary , Egri Csilla , Sayson Bryan , Milea Janetta , Stockler-Ipsiroglu Sylvia , Huh Linda , Connolly Mary B. , Horvath Gabriella A. 
Published: March 2018

AbstractBackground:Secondary neurotransmitter deficiencies have been reported in several reviews. Our primary aim was to assess the relationship among epilepsy, antiseizure medications, and specific neurotransmitter abnormalities. We also evaluated movement disorders and brain abnormalities via magnetic resonance imaging scans in patients with secondary neurotransmitter defects.Methods:This is a retrospective case series of 376 patients who underwent neurotransmitter analysis at BC Children’s Hospital between 2009 and 2013, for a variety of neurological presentations. The biochemical genetics laboratory database was interrogated for results of cerebrospinal fluid neurotransmitter analyses. Clinical data for patients with abnormal results were collected from the hospital charts. Statistical analysis included one-way analysis of variance, chi-square, and a two-way contingency table.Results:Abnormal neurotransmitter values were identified in 67 (17.8%) patients, two (0.53%) of which were attributable to a congenital neurotransmitter disorder and 11 (16.9%) secondary to other genetic diagnoses. Of 64 patients with secondary abnormal neurotransmitter values, 38 (59%) presented with epilepsy and 20 (31%) with movement disorders. A combination of epilepsy and movement disorder was less frequent.Discussion:Acknowledging the limitations of this retrospective chart review, we conclude that, in our cohort, in addition to patients with movement disorders, a considerable number of patients with epilepsy and epileptic encephalopathy also showed secondary neurotransmitter mono-amine abnormalities. There is no clear relation, however, between clinical phenotype and type of neurotransmitter affected. In addition, no association was identified between the type of antiseizure medications and affected neurotransmitter type. We outline the need for prospective studies to further enrich our understanding of the relation between epilepsy and neurotransmitters with a focus on improving treatments and patient outcomes.
Three-dimensional wake transition of a square cylinder
Authors: Jiang Hongyi , Cheng Liang , An Hongwei 
Published: March 2018

Three-dimensional (3-D) wake transition for flow past a square cylinder aligned with sides perpendicular and parallel to the approaching flow is investigated using direct numerical simulation. The secondary wake instability, namely a Mode A instability, occurs at a Reynolds number ($Re$) of 165.7. A gradual wake transition from Mode A* (i.e. Mode A with vortex dislocations) to Mode B is observed over a range of $Re$ from 185 to 210, within which the probability of occurrence of vortex dislocations decreases monotonically with increasing $Re$. The characteristics of the Strouhal–Reynolds number relationship are analysed. At the onset of Mode A*, a sudden drop of the 3-D Strouhal number from its two-dimensional counterpart is observed, which is due to the subcritical nature of the Mode A* instability. A continuous 3-D Strouhal–Reynolds number curve is observed over the mode swapping regime, since Mode A* and Mode B have extremely close vortex shedding frequencies and therefore only a single merged peak is observed in the frequency spectrum. The existence of hysteresis for the Mode A and Mode B wake instabilities is examined. The unconfined Mode A and Mode B wake instabilities are hysteretic and non-hysteretic, respectively. However, a spanwise confined Mode A could be non-hysteretic. It is proposed that the existence of hysteresis at a wake instability can be identified by examining the sudden/gradual variation of the 3-D flow properties at the onset of the wake instability, with sudden and gradual variations corresponding to hysteretic (subcritical) and non-hysteretic (supercritical) flows, respectively.
Topological analysis of graphoglyptid trace fossils, a study of macrobenthic solitary and collective animal behaviors in the deep-sea environment
Authors: Fan Ruo-ying , Gong Yi-ming , Uchman Alfred 
Published: March 2018

AbstractGraphoglyptids are biogenic structures commonly found in deep-sea flysch deposits and occasionally detected on the modern deep-sea floor. They extend principally horizontally and take a variety of geometric patterns, whose functional morphology remains an enigma in ichnology and paleoceanography. Based on published materials from 1850 to 2017 (79 ichnotaxa from 28 ichnogenera of graphoglyptids) and systematic observations of one of the largest deep-sea trace fossil collections in the world, this paper proposes that topological analysis is an important ingredient in the taxonomy and functional interpretation of graphoglyptids. Accordingly, graphoglyptids are classified into line, tree, and net forms by their key topological architecture, and are further attributed to 19 topological prototypes by detailed secondary topological features. Line graphoglyptids are single-connected structures with uniform tunnel width, representing primarily the feeding patterns of solitary animals. Tree graphoglyptids, the most diverse architectural group of graphoglyptids, are ascribed to 11 topological prototypes according to the connectivity features of burrow segments and the number and distributional pattern of the branching points. Net graphoglyptids are subdivided into three topological prototypes on the basis of the connectivity features and/or the regularity of the meshes. Multiconnected net forms are considered as a continuous morphological spectrum with different levels of complexity in the net formation. The various connected components in multiconnected tree and net graphoglyptids generally exhibit small and uniform tunnel diameter in a given structure (suggesting a tiny trace maker[s]). The whole structure shows relatively extensive linear or surface coverage and overall good preservation, indicating sustained processes of burrow construction. It is highly probable that certain multiconnected tree and net graphoglyptids represent some emergent patterns from self-organized collective behaviors of conspecific animals. Graphoglyptids thus provide us with a new perspective on the study of solitary and collective behaviors of macrobenthos in the deep-sea environment.