bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of biomarkers related to anoikis in liver cirrhosis based on bioinformatics analysis
Authors: Luo Jiang-Yan , Zheng Sheng , Yang Juan , Ma Chi , Ma Xiao-Ying , Wang Xing-Xing , Fu Xin-Nian , Mao Xiao-Zhou 
Published: November 2024

BACKGROUND
According to study, anoikis-related genes (ARGs) have been demonstrated to play a significant impact in cirrhosis, a major disease threatening human health worldwide.
AIM
To investigate the relationship between ARGs and cirrhosis development to provide insights into the clinical treatment of cirrhosis.
METHODS
RNA-sequencing data related to cirrhosis were obtained from the Gene Expression Omnibus database. Differentially expressed genes (DEGs) between cirrhotic and normal tissues were intersected with ARGs to derive differentially expressed ARGs (DEARGs). The DEARGs were filtered using the least absolute shrinkage and selection operator, support vector machine recursive feature elimination, and random forest algorithms to identify biomarkers for cirrhosis. These biomarkers were used to create a nomogram for predicting the prognosis of cirrhosis. The proportions of diverse immune cell subsets in cirrhotic vs normal tissues were compared using the CIBERSORT computational method. In addition, the linkage between immune cells and biomarkers was assessed, and a regulatory network of mRNA, miRNA, and transcription factors was constructed relying on the biomarkers.
RESULTS
The comparison of cirrhotic and normal tissue samples led to the identification of 635 DEGs. Subsequent intersection of the DEGs with ARGs produced a set of 26 DEARGs. Subsequently, three DEARGs, namely, ACTG1 , STAT1 , and CCR7 , were identified as biomarkers using three machine-learning algorithms. The proportions of M1 and M2 macrophages, resting CD4 memory T cells, resting mast cells, and plasma cells significantly differed between cirrhotic and normal tissue samples. The proportions of M1 and M2 macrophages, resting CD4 memory T cells, and resting mast cells were significantly correlated with the expression of the three biomarkers. The mRNA–miRNA–TF network showed that ACTG1 , CCR7 , and STAT1 were regulated by 28, 42, and 35 miRNAs, respectively. Moreover, AR, MAX, EP300, and FOXA1 were found to regulate four miRNAs related to the biomarkers.
CONCLUSION
This study revealed ACTG1 , STAT1 , and CCR7 as biomarkers of cirrhosis, providing a reference for developing novel diagnostic and therapeutic strategies for cirrhosis.
La expresión corporal como alternativa metodológica para la inclusión de estudiantes con discapacidad física
Authors: Barzola Ochoa Fausto Eduardo , Catagua Pallo Cristhian Jonathan , Romero Ibarra Orlando Patricio , Maqueira Caraballo Giceya de la Caridad 
Published: November 2024

Introducción: La expresión corporal es una comunicación no verbal que utiliza el cuerpo como medio para transmitir emociones, sentimientos e ideas, pudiendo ser un método efectivo para la inclusión de estudiantes discapacitados en las clases de educación física. Objetivo: Analizar los criterios del profesorado y del alumnado sobre la expresión corporal como alternativa a la inclusión en la educación física de estudiantes discapacitados, sirviendo de base teórica para diseñar una alternativa metodológica de expresión corporal para mejorar la inclusión de estudiantes con discapacidad en las clases de educación física. Método: investigación descriptiva/explicativa de orden correlacional, encuestando profesores (n=25) y alumnos (n=25) sobre la importancia y aplicabilidad de la expresión corporal en las en las clases de educación física. Resultados: No existe concordancia en los criterios emitidos por el profesorado (k=0,283) ni el alumnado (k=0,293). El profesorado emite solamente su voto positivo en la séptima pregunta (X̅3,16 - De Acuerdo), coincidiendo que la expresión corporal es una herramienta efectiva para la inclusión. El alumnado emite su voto positivo en cuatro preguntas (≥3puntos), valorando los aportes de la expresión corporal como estrategia positiva para la inclusión de estudiantes con discapacidad. Se diseña una propuesta con varias actividades de expresión corporal, validadas positivamente por especialistas (k=0,777). Conclusiones: Se evidencia desconocimiento del profesorado sobre la importancia y alcance de la expresión corporal, requiriendo superación profesional intensiva, mientras que el alumnado posee mejores calificaciones medias en sus criterios sobre la contribución de la expresión corporal, requiriendo adicionalmente un proceso práctico de intervención especializada.
THE FORMATION OF THE FRANKISH PERIOD AND ITS INFLUENCE ON THE FIELD OF ONOMASTICS
Authors: Seyid Vafa 
Published: November 2024

This article is based on the linguistic study of the formation of the Frankish and its influence on the field of onomastics. The article highlights the opinions of historical researchers about the gradual formation of the Frankish period since ancient times, and sometimes these opinions create polemics between them. At the same time, it is said that throughout history, various tribes gathered in the territory of the Frankish empire and created a state and language, and these tribes' languages influenced on the field of onomastics. The article also reflects the presence of mythical considerations in the field of onomastics, the inclusion of an important lexicon in the field of toponymy as a result of the German occupation, as well as in the vocabulary of Gallo-Romance. It is noticeable that the names were formed by the bithematic and monothematic method by adding the suffixes -IÄCU, -VILLE and -CURT, and then the suffix -COURT on a chronological scale. The article provides information about the areas where the tribes settled within the empire and the necropolises, as well as the falsified place names created on the basis of hypocoristic (hypocritical) names around these necropolises through maps. The article concludes that, according to the new methodology of contact linguistics, all the toponyms included in the study are indeed Romanic formations, contrary to the widespread opinion that still tries to interpret them as Germanic derivatives. Thanks to archeology, it can be proven that the monothematic and hypocoristic variants of Frankish anthroponyms, which appeared as "small names" among the Franks and took on an "informal" character, were not used by the Roman population to create toponyms.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0721/a.php" alt="Hit counter" /></p>
EFFECT OF FUNDING STRUCTURE AND LIQUIDITY ON THE FINANCIAL PERFORMANCE OF THE SUGAR INDUSTRY IN KENYA
Authors: Oando Odoyo Samson , Ombok Benjamin O. 
Published: November 2024

<p>The main objective of this study was to establish the effect of liquidity on the financial performance of the sugar industry in Kenya. The correlation between financial performance and liquidity in the Kenyan sugar industry is significant, ensuring the sector can meet immediate obligations and maintain smooth operations. Low liquidity can disrupt profitability and long-term stability, while high liquidity improves operational efficiency. Applying Stockholder and Liquidity Preference Theories to guide the study while employing correlational research design on a target population of 16 sugar companies operational in Kenya, sampled for 9 sugar companies, a total of 324 secondary data points from 2014 to 2022 were collected. Data was collected on the cost of the current ratio, acid test ratio, and economic value added, all derived from financial statements and cash flows. The results revealed a significant and positive relationship between liquidity and Economic value added (coefficient 0.939539, p=0.000&lt;0.05); implying that liquidity has a significant relationship with economic value added. The findings are relevant for investors, policymakers, and factory managers. The study recommends that factory managers and policymakers ensure healthy liquidity within the sugar industries.</p><p> </p><p><strong>JEL: </strong>M41, G30, G32</p><p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0735/a.php" alt="Hit counter" /></p>
HEAD TEACHERS' CANDIDATE PREPARATION STRATEGIES AND STUDENTS’ PERFORMANCE IN THE PRIMARY CERTIFICATE OF EDUCATION IN CHIMOIO DISTRICT, MOZAMBIQUE
Authors: Tito Victoria , Okemasisi Kinikonda , Wambui Rose 
Published: November 2024

The purpose of this study was to investigate the influence of head teachers' candidate preparation strategies on students’ performance in the Primary Certificate of Education in Chimoio District, Mozambique. The objectives of this study were: to examine the influence of examination anxiety management on students’ academic performance and to evaluate the influence of motivation strategy on students’ academic performance in the Primary Certificate of Education in Chimoio District, Mozambique. A convergent parallel mixed method design was used. The study adopted a cross-sectional survey research design for quantitative data and a phenomenological design for qualitative data. The focus was on public primary schools, head teachers, teachers and Mozambique’s Ministry of Education officer. Simple random sampling was used to select 18 out of 23 primary schools and 125 out of 312 teachers; criterion purposive sampling was used to select 18 head teachers and 1 Ministry of Education officer. Proportionate sampling, simple random sampling, was used to select 316 out of 1500 students. Questionnaires were used to collect data from students and teachers. An interview guide was used to collect data from head teachers and the Ministry of Education officer. Instrument reliability was tested using the test-retest technique, where a score of 0.82 was realized. Quantitative data was analyzed using SPSS version 25, and findings were reported in percentages, frequency tables, and graphs. The qualitative data were analyzed into themes according to the research questions and reported in narratives and direct quotations. The study revealed that head teachers’ candidate preparation strategies, including, exam anxiety management and student motivation, have an influence on students’ academic performance in the Primary Certificate of Education in Chimoio District, Mozambique. The study recommended that in preparing candidates for examinations, head teachers should prioritize and promote intrinsic motivation strategies. These include fostering a supportive learning environment, encouraging student autonomy, and emphasizing the value of learning itself. Such strategies are expected to have a more sustainable and positive impact on student engagement and academic performance.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0615/a.php" alt="Hit counter" /></p>
NEUROPSYCHOPEDAGOGICAL PERSPECTIVE: RELATIONSHIPS BETWEEN WORKING MEMORY AND MOTOR, INHIBITORY CONTROL, AND LINGUISTIC DEVELOPMENT IN ELEMENTARY SCHOOL
Authors: Cardoso Fabrício Bruno , Bonone Filipe M. , Loureiro Vitor da Silva , Sholl-Franco Alfred 
Published: November 2024

Working memory plays a pivotal role in cognitive functioning, serving as a dynamic interface for processing and integrating information across various domains. It is crucial for executing complex tasks such as reading comprehension, mathematical problem-solving, and logical reasoning. This study investigates the relationship between working memory and motor skills, inhibitory control, and language abilities in elementary school students, highlighting the role of specific assessment instruments in this analysis. The research involved 1107 students, aged 7 to 10 years, from public schools in Joinville, Brazil. Working memory was evaluated using the Neuropsychopedagogical Screening Scale for Working Memory (NSSWM), which comprises 23 items that assess the temporary storage and processing of information needed for tasks such as language comprehension, arithmetic, and problem-solving. Motor skills were assessed using the Neuropsychopedagogical Screening for Children's Motor Development, a 7-item scale focusing on motor coordination, fine motor control, and organizational skills during school activities. Inhibitory control was measured with the Child Inhibitory Control Screening Scale (CICS), which includes 18 scenarios that evaluate inhibitory responses, planning, and impulsivity. Phonological skills were assessed using the Screening Scale for Phonological Skills (SSPS), which measures the ability to recognize formal language characteristics through 17 items. Lastly, reading and writing skills were evaluated using the Children's Reading and Writing Screening Scale (CRWSS), a 16-item scale designed to identify potential difficulties in acquiring these skills in a school setting. The results revealed significant correlations between working memory and other cognitive domains, with motor skills exhibiting the strongest association (r=0.916, p=0.012). Additionally, inhibitory control (r=0.732, p=0.028) and phonological awareness (r=0.815, p=0.034) showed strong correlations with working memory, indicating that students with better-developed skills in these areas tend to perform better in working memory tasks, which, in turn, positively impacts their academic performance. The study underscores the importance of early neuropsychopedagogical interventions that address both cognitive and motor development. By employing specific, targeted assessment instruments, educators and mental health professionals can better identify students at risk of academic difficulties and implement effective strategies to enhance their cognitive and behavioral development, ultimately fostering a more supportive and inclusive learning environment.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0525/a.php" alt="Hit counter" /></p>
THE INFLUENCE OF FAMILY DYSFUNCTION ON ADOLESCENT PSYCHOLOGICAL HEALTH: A LITERATURE REVIEW-BASED STUDY
Authors: Tian Xiaoqing , Chen Pengfei 
Published: November 2024

The increasing prevalence of adolescent psychological health issues worldwide has become a significant public health concern affecting the future. Families, as the primary environment providing material and emotional support for adolescent development, play a crucial role in fostering growth and psychological well-being. This study employed a literature review methodology, using keywords such as family dysfunction, adolescents, and psychological health, to search for definitions of family dysfunction and relevant literature about its effects on adolescents' psychological health. The review study summarized the definitions of family dysfunction, related research, and its impact on adolescent psychological health. The findings suggest that addressing the impact of family dysfunction on adolescent psychological health effectively requires collaborative efforts from families, schools, and society. Establishing collaborative prevention and intervention mechanisms among family, schools and society, providing educational programs to improve family function, and adopting family-centered intervention strategies are essential steps toward solving this critical issue.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0200/a.php" alt="Hit counter" /></p>
THE SOCIO-ECONOMIC FACTORS INFLUENCING TEACHER ENROLLMENT IN UNDERGRADUATE AND POSTGRADUATE PROGRAMMES IN ZAMBIA
Authors: Matafwali Marien , Rolls Douglas, W. , Sikazwe Webster , Njovu Chiyaba 
Published: November 2024

The study focused on the socio-economic factors influencing teacher enrolment in undergraduate and postgraduate programmes in Zambia. It employed Human Capital Theory and a mixed-methods approach. A sequential exploratory research design was adopted for the current study. Data were collected from six provinces and comprised a total of 240 respondents. A questionnaire and interview guide were used to collect data. Qualitative data underwent thematic analysis, while quantitative data were analysed using the Statistical Package for Social Sciences (SPSS) to generate frequencies and percentages. Multiple regression and T-test were also used to test the hypothesis. The study reveals that socio-economic factors significantly influence teacher enrolment in education programs in Zambia. Key factors such as Economic Affordability (EA) and Availability of Scholarships (AS) are highly influential, as shown by multiple regression analysis indicating significant positive relationships (EA: β=0.597, p=0.016; AS: β=0.418, p=0.004). Other significant factors include Socio-economic Background of Teachers (SBT: β=0.665, p=0.033), Government Support Programmes (GSP: β=0.316, p=0.002), Perception of Career Advancement Opportunities (PCAO: β=0.798, p=0.000), Study Leave Opportunities (SLO: β=0.676, p=0.037), Cultural and Social Norms (CSN: β=0.227, p=0.009), and Family Support and Responsibilities (FSR: β=0.612, p=0.000). Challenges such as financial constraints, lack of government support, and work-life balance were identified as significant barriers to enrolments in postgraduate programmes. Recommendations included: implementing financial support, offering flexible learning options, promoting the benefits of further education, and establishing support networks with mentorship.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0815/a.php" alt="Hit counter" /></p>
EARLY COMMUNICATION INDICATOR-PORTUGAL: EVIDENCE FOR ITS USE IN ASSESSING AND MONITORING COMMUNICATION IN YOUNG CHILDREN
Authors: Ferreira Sandra , Cruz-Santos Anabela , Almeida Leandro S. 
Published: November 2024

The need for effective, globally validated tools to assess and monitor communication in early childhood has led different populations to explore and adapt tools that have already been validated in other countries and languages. A promising tool to support the assessment and monitoring of early communication is the Early Communication Indicator (ECI), developed in the USA. The ECI has recently been adapted for the Portuguese population, and the aim of this paper is to describe its characteristics and report the results obtained with Portuguese children aged between 6 and 42 months, presenting evidence for its use in assessing and monitoring communication in Portuguese children at an early age. This evidence shows the sensitivity of the ECI-Portugal in capturing the changes that occur throughout the communicative development of Portuguese children in the early years, and in identifying differences between children with and without communication disorders. Further research is needed to advance the development of the ECI in the Portuguese context. Consequently, a discussion of the research and practical steps needed to move this project forward is presented.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0798/a.php" alt="Hit counter" /></p>
“CORPSE OF DUST” (XÁC BỤI) SHORT STORY OF NGUYEN NGOC TU FROM THE PERSPECTIVE OF PSYCHOANALYSIS
Authors: Nghia Vo Minh 
Published: November 2024

With the short story “Corpse of dust” (Xác bụi), Nguyen Ngoc Tu has created a new and impressive view of how to build a plot according to psychological characteristics. The story structure is a series of developments in the psychology of Diu's character revolving around the subtleties and sensitivity to many changing events of life. Using the psychoanalytic structure from the theory of psychoanalysis, the confusion in the protagonist's psychology is explained by the system of the “ID”, the “ego” and the “superego”. The psychological struggle of wrong times and deviations from moral norms is clearly exposed in the sympathetic gaze of readers. The Psychoanalytic Theory has helped those who come into contact with this short story to be touched and sad for the love, meaning and fidelity of the girls in the Southwest of Vietnam when in love.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0799/a.php" alt="Hit counter" /></p>
THE INFLUENCE OF ORGANISATIONAL CLIMATE AND RESPONSIBLE LEADERSHIP ON INNOVATIVE BEHAVIOUR OF EMPLOYEES IN HIGHER INSTITUTIONS OF LEARNING IN GHANA
Authors: Mumuni Aliata Issahaq , Appah George Obeng , Biaku Kennedy Afenyo 
Published: November 2024

This study studies the relationship between organisational climate, responsible leadership, and innovative behaviour and their subsequent impact on employee performance. The study uses hypothesis testing research design based on quantitative research designs and sampled 145 employees from Simon Diedong University of Business and Integrated Development Studies (SDD UBIDS) and Dr. Hilla Limann Technical University, Wa (DHLTU-Wa) in the Upper West region of Ghana. Key findings in this study are: (1) organizational climate has an insignificant positive effect on innovative behaviour (2) responsible leadership significantly and positively influences innovative behaviour (3) management systems and social environment do not significantly impact innovative behaviour (4) physical environment has a significant positive effect on innovative behaviour. The study reveals that organisational climate and responsible leadership are significant predictors of innovative behaviour, with a strong correlation (0.768) between these variables. The regression analysis shows that 59.1% (R^2 = 0.591) of the variance in innovation is explained by organisational climate and responsible leadership, while 40% is attributed to other factors. Overall, this quantitative study highlights the crucial role of responsible leadership and the physical environment.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0699/a.php" alt="Hit counter" /></p>
“PHYSICAL EDUCATION OR NOT?’’ THE PSYCHOLOGICAL EFFECTS OF PHYSICAL ACTIVITIES ON COLLEGE STUDENTS
Authors: Agar Mannar G. , Alonzo Mariah Carla G. , Gabas Roslene A. , Singson Ivy V. 
Published: November 2024

For many years, many studies have shown the purpose of physical activity as a medium to improve one's physical health. However, it does not have enough studies on how physical activity can benefit an individual's psychological well-being. Although some researchers say physical activity can help reduce stress, people still wonder whether physical activity correlates with psychological well-being. This study stated that physical activity is considered one of the most important aspects of an individual's life. It stands as a firm block in improving general well-being and helps individuals feel motivated and relieved from stress. This study utilized the descriptive qualitative design and purposive sampling following the key informant interview, where the data is required straightforwardly from 25 people who encounter the phenomenon being investigated. They also applied code reliability thematic analysis in interpreting the data collected and distinguished common themes, topics, ideas, and meaning patterns, which resurface consistently in the interview session. Moreover, this research's key findings present the effectiveness of engaging in physical activity and considerations that can increase the benefit of improving one's psychological aspect.<p> </p><p><strong> Article visualizations:</strong></p><p><img src="/-counters-/soc/0724/a.php" alt="Hit counter" /></p>