bluuebunny/crossref_metadata_2025_split huggingface dataset:
1399-P: The Accumulative Impact of Insulin Sensitivity throughout Pregnancy on Neonatal Fatness
Authors: LIMA RODRIGO ANTUNES , VAN POPPEL MIREILLE , SIMMONS DAVID , DESOYE GERNOT ,   DALI CORE INVESTIGATOR GROUP
Published: June 2019

Aim: To evaluate the direct and indirect associations between insulin sensitivity during pregnancy and neonatal fatness.
Methods: This is a longitudinal, secondary analysis of the DALI study which was a multicenter study conducted in nine European countries. Pregnant women with a pre-pregnancy body mass index (BMI) of ≥29 kg/m2, &lt;20 weeks of gestation, a singleton pregnancy, and aged ≥18 years were invited to participate. Women diagnosed with early gestational diabetes were excluded. Neonatal fatness was estimated by the sum of triceps, subscapular, supra iliac and quadriceps skinfolds. Maternal insulin sensitivity (HOMA), fasting glucose, triglycerides (TG) and free fatty acids (FFA) were measured three times during pregnancy (13-20, 24-28, and 35-37 weeks of gestation). Structured equation modelling was performed to evaluate the direct and indirect relationship between variables of interest. Analysis was adjusted for maternal ethnicity, maternal education, maternal age, gestational age and neonatal age and results were presented in standard deviations (SD).
Results: In total, 701 mother-infant pairs (51.0% boys) were included. Neonatal girls exhibited higher sum of skinfolds compared to boys (20.5 mm [±5.5] vs. 21.6 mm [±5.3]; p=0.03). HOMA at 13-20 weeks but not at 24-28 or 35-37 weeks was associated with neonatal fatness. This association was mediated through Glucose13-20weeks -&gt; Glucose24-28weeks -&gt; Glucose35-37weeks (0.599 SD for boys and 0.467 SD for girls) and TG13-20weeks -&gt; TG24-28weeks -&gt; TG35-37weeks (0.464 SD for boys and 0.497 SD for girls). The pathway with FFA did not mediate the association between HOMA and neonatal fatness.
Conclusions: Maternal health profile in the first trimester of pregnancy plays an important role in neonatal body fatness, since insulin sensitivity was associated with neonatal fatness via increases in HOMA-Index, glucose and triglycerides throughout pregnancy.

Disclosure
R.A. Lima: None. M. van Poppel: None. D. Simmons: Speaker's Bureau; Self; Sanofi-Aventis. Other Relationship; Self; Medtronic. G. Desoye: None.

Funding
European Community's 7th Framework Program (FP7/2007-2013)
455-P: Levels of Plasma Prekallikrein Predict Myocardial Infarction in Non-Hispanic White Participants of the Veterans Affairs Diabetes Trial (VADT)
Authors: HUNT KELLY J. , JAFFA MIRAN A. , SOHN MIMI , LOPES-VIRELLA MARIA F. , JAFFA AYAD A. ,   VADT INVESTIGATORS
Published: June 2019

We hypothesize in diabetes that augmented activity of the plasma kallikrein-kinin system reflect and contribute to vascular damage and inflammations. Our objective was to determine the role of plasma PK as a predictor of cardiovascular events in type 2 diabetes in the VADT cohort. Levels of plasma total prekallikrein (PK) were measured in 604 VADT patients, a median of 1.5 years after entry into the study. Participants were followed an average of 4.1 years. Hazard ratios (HRs) for CV endpoints in relation to PK tertiles and having a non-zero versus zero value for plasma active kallikrein (PAK) were calculated by Cox proportional hazard models. During follow-up, 4.9% had an MI and 7.4% had an MI or cardiovascular death. Because there was evidence that minority status modified the associations between PK and outcomes of interest, but there was very limited power in minorities, results are presented in the total population adjusting for minority status and limited to the non-Hispanic white (NHW) population (Table). After adjustments by conventional risk factors, in NHW individuals the hazard ratio comparing the middle to lowest tertile of PK levels was 3.94 (95% CI: 1.09, 14.2) for MI and 3.45 (95% CI: 1.25, 9.48) for MI combined with cardiovascular death. Our study indicates that plasma PK levels predict MI and cardiovascular death in NHW patients with type 2 diabetes.

Disclosure
K.J. Hunt: None. M.A. Jaffa: None. M. Sohn: None. M.F. Lopes-Virella: None. A.A. Jaffa: None.

Funding
National Heart, Lung, and Blood Institute
NLRP3 and CARD8 polymorphisms influence risk for asbestos-related diseases
Authors: Franko Alenka , Goricar Katja , Kovac Viljem , Dodic-Fikfak Metoda , Dolzan Vita 
Published: June 2019

Summary

Background
This study aimed to investigate the association between NLRP3 rs35829419 and CARD8 rs2043211 polymorphisms and the risk of developing pleural plaques, asbestosis, and malignant mesothelioma (MM), and to study the influence of the interactions between polymorphisms and asbestos exposure on the risk of developing these diseases.

Methods
The case-control study included 416 subjects with pleural plaques, 160 patients with asbestosis, 154 subjects with MM and 149 subjects with no asbestos disease. The NLRP3 rs35829419 and CARD8 rs2043211 polymorphisms were determined using real-time PCR-based methods. In the statistical analysis, standard descriptive statistics was followed by univariate and multivariate logistic regression modelling.

Results
Asbestos exposure (medium and high vs low) was associated with the risk for each studied asbestos-related disease. An increased risk of pleural plaques was found for CARD8 rs2043211 AT + TT genotypes (OR = 1.48, 95% CI 1.01–2.16, p = 0.042). When the analysis was performed for MM patients as cases, and pleural plaques patients as controls, a decreased MM risk was observed for carriers of CARD8 rs2043211 TT genotype (OR = 0.52, 95% CI 0.27–1.00, p = 0.049). The interactions between NLRP3 rs35829419 and CARD8 rs2043211 genotypes did not influence the risk of any asbestos-related disease. However, when testing interactions with asbestos exposure, a decreased risk of asbestosis was found for NLRP3 CA+AA genotypes (OR = 0.09, 95% CI 0.01–0.60, p = 0.014).

Conclusions
The results of our study suggest that NLRP3 and CARD8 polymorphisms could affect the risk of asbestos-related diseases.
Revised definition/outline of the Kheis Terrane along the western margin of the Kaapvaal Craton and lithostratigraphy of the newly proposed Keis Supergroup
Authors: van Niekerk H.S. , Beukes N.J. 
Published: June 2019

AbstractThe Kheis Province is situated between the Namaqua-Natal Province and the western margin of the Kaapvaal Craton in the Northern Cape Province of South Africa. It has been described as a thin-skinned fold and thrust belt formed between 1800 and 1700 Ma. The lithostratigraphic subdivision of the rock units comprising the Kheis Province has been a source of much controversy. From detailed study of aerial photography and satellite imagery, as well as field-based studies, the outcrop patterns in the Kheis Province and Kaaien Terrane were reinterpreted and a new stratigraphic subdivision is outlined here. It is proposed that the structural Kaaien Terrane and Kheis Province should be combined into the Kheis Terrane and that the rocks occurring in the Kheis Terrane should be grouped together to form the new Keis supergroup, with the basal metaconglomerate of the Mapedi/Gamagara Formation recognised as the regional unconformity between the Keis supergroup and the underlying rocks of the Transvaal Supergroup in the Griqualand West area. The Keis supergroup is subdivided from the base upwards into the Elim-, Olifantshoek-, Groblershoop- and Wilgenhoutsdrif groups. The basal Elim group is composed of the Mapedi/Gamagara- and Lucknow formations. It is overlain with a regional erosional unconformity by the Olifantshoek group, which is made up of the Neylan-, Hartley-, Volop- and Top Dog formations. The Olifantshoek group is conformably overlain by the Groblershoop group which is comprised of three upward coarsening successions:the Faanshoek- and Faansgeluk formations,the Maraisdraai- and Vuilnek formations andthe Opwag- and Skurweberg formations.The Groblershoop group is in turn erosively overlain by the rocks of the Wilgenhoutsdrif Group, which include the basal erosive Groot Drink formation which is overlain by the Zonderhuis- and Leerkrans formations. The lithologies of the Keis supergroup are in faulted contact with the rocks of the younger Areachap Group of the ~1200 Ma Namaqua-Natal Metamorphic Province.
Fotodegradasi Air Sungai Landak dengan Polimer Polipropilena Berfotokatalis Semikonduktor TiO2
Authors: Rokayah Rokayah , Asri Asifa , Malino Mariana Bara'allo , Lapanporo Boni Pahlanop 
Published: June 2019

Penelitian ini mempelajari fotodegradasi air Sungai Landak dengan material penyangga polimer polipropilena (PP) berfotokatalis semikonduktor TiO2. Disamping itu, dilakukan pula analisis untuk mengetahui hubungan antara jumlah TiO2 yang terdeposisi di permukaan PP dengan variasi suhu saat proses pabrikasi. Pabrikasi PP/TiO2 dilakukan dengan teknik deposisi thermal milling. Dari hasil pabrikasi yang dilakukan, diketahui bahwa TiO2 paling banyak terikat pada permukaan PP pada suhu milling dengan massa TiO2 sebesar 1,7 gram. Sedangkan, hasil degradasi yang paling optimum (absorbansi maksimum = 1,446) diperoleh PP/TiO2 dengan suhu milling setelah fotodegradasi selama 40 jam. Walaupun suhu milling menghasilkan massa TiO2 terdeposisi pada permukaan PP yang paling tinggi, namun tidak diiringi dengan hasil degradasi terbaik. Hal ini dikarenakan adanya indikasi overlapping antar TiO2 sehingga menyebabkan luas permukaannya menjadi lebih kecil dan membuat proses fotodegradasi menjadi tidak optimal. Akhirnya untuk parameter pH, semua sampel yang diberikan PP/TiO2 mengalami kenaikan nilai pH dari 4,9 menjadi 6,6 (suhu milling 100 ), menjadi 6 (suhu milling 150 dan 200 ), menjadi 5,7 (suhu milling 125 ), dan menjadi 5,3 (suhu milling 175 ). Nilai pH air sungai setelah ditambahkan PP/TiO2 pada suhu milling 175 tergolong pH<pzc sehingga mendukung terjadinya degradasi sampel air yang lebih cepat daripada variasi suhu milling yang lain.
Analisis Pengaruh Kuat Arus dan Tegangan Terhadap Kualitas Citra Computed Tomography (CT) Scan Siemens Perspective di RSUP Dr. M. Djamil Padang
Authors: Herlinda Sri , Fitriyani Dian , Marzuki Marzuki 
Published: June 2019

Telah dilakukan analisis pengaruh kuat arus dan tegangan terhadap kualitas citra Computed Tomography (CT) Scan menggunakan phantom Siemens berbentuk silinder dengan metode pengambilan citra secara pemindaian axial. Variasi tegangan tabung yang digunakan adalah 80 kV, 110 kV dan 130 kV, untuk kuat arus 240 mA, 260 mA, 280 mA, 300 mA, 320 mA dan 340 mA dengan waktu pemindaian 1 detik. Setiap metode pemindaian untuk satu tegangan dilakukan dengan enam kali penyinaran. Penyinaran dilakukan pada dua keadaan yaitu pada tegangan tetap, nilai kuat arus yang divariasikan dan untuk variasi tegangan dilakukan pada nilai kuat arus yang tetap, dengan menggunakan ketebalan irisan 8 mm dengan kernel J30s. Hasil penelitian menunjukkan bahwa kenaikan tegangan tabung diikuti oleh dan penurunan nilai noise dan kenaikan nilai uniformity . Selain itu, variasi penambahan arus tabung akan menurunkan nilai noise dan menurunkan nilai uniformity. Nilai noise yang paling optimal berada pada tegangan 110 kVp dan 130 kVp, sedangkan nilai uniformity yang paling optimal berada pada tegangan 80 kVp dengan kuat arus 300 mAs dan 340 mAs.
Aplikasi Spektrofotometer Kisi Sederhana dan Lampu Pijar pada Eksperimen Radiasi Benda Hitam untuk Penentuan Konstanta Plank
Authors: Nugroho Bintoro Siswo , Pernandes Yudi , Lapanporo Boni Pahlanop 
Published: June 2019

Telah dilakukan rancang bangun spektrofotometer untuk menganalisis spektrum cahaya tampak yang digunakan pada eksperimen radiasi benda hitam dalam penentuan konstanta Planck. Komponen utama alat ini terdiri dari lampu pijar sebagai sumber radiasi benda hitam, kolimator sebagai pengarah sinar, lensa cembung sebagai pengkonsentrasi sinar, kisi difraksi sebagai pendispersi, dan kamera sebagai detektor, serta perangkat lunak Tracker sebagai program analisis data. Spektrum radiasi benda hitam direkam untuk empat variasi suhu yang diperoleh dengan mengubah besar arus masuk pada lampu pijar. Agar suhu benda hitam dapat ditentukan dengan lebih akurat, derau spektrum dihilangkan dengan melakukan fiting polinomial orde 10 pada data. Dari data yang diperoleh, nilai konstanta Planck dihitung dengan membandingkan dua intensitas spektrum pada panjang gelombang yang sama. Berdasarkan perhitungan, didapatkan nilai Planck sebesar h=(5,65±1,53)×10^(-34) J s. Meskipun akurasinya masih perlu ditingkatkan, metode ini memiliki keuntungan berupa prosedur eksperimen yang lebih sederhana dan adanya informasi visual spektrum benda hitam dalam representasi warna maupun grafik. Hal tersebut dapat membantu mahasiswa memahami karakteristik spektrum malar radiasi termal yang sangat berbeda dari spektrum diskrit deeksitasi atomik.
TỔNG HỢP HẠT NANO VÀNG ĐƯỢC ỔN ĐỊNH BỞI DEXTRAN
Authors: DIỄM PHAN NỮ , HÒA TRẦN THÁI , BÌNH TRẦN THÚC 
Published: June 2019

Tóm tắt – Hạt nano vàng (AuNPs) hình cầu, có kích thước khoảng 6-15 nm được tổng hợp bằng phương pháp khử hóa học, với dextran là chất ổn định. Máy khuấy từ được dùng để trộn hỗn hợp dung dịch axit tetrachloroauric và dextran ở nhiệt độ phòng. Ảnh hưởng của thời gian khử, nồng độ Au3+ và nồng độ dextran đến kích thước của AuNPs đã được khảo sát. Vi cấu trúc của AuNPs được đặc trưng bởi phổ UV-Vis, phương pháp nhiễu xạ tia X (XRD) và kính hiển vi điện tử truyền qua (TEM). Kết quả cho thấy, AuNPs có kích thước nhỏ, độ đồng nhất cao được tổng hợp ở nhiệt độ phòng, nồng độ Au3+ là 0,50 mM, dextran là 1,0 % và pH = 12. Khi dung dịch Au3+ ở nồng độ thấp, sản phẩm là AuNPs có kích thước nhỏ nhưng ngược lại, khi dextran ở nồng độ thấp, sản phẩm thu được là AuNPs có kích thước lớn. Bột AuNPs thu được bằng phương pháp sấy phun. Độ tinh khiết của bột AuNPs được kiểm tra bằng phổ tán sắc năng lượng tia X (EDX). AuNPs dạng dung dịch hoặc dạng bột được ổn định bởi dextran - chất tương thích sinh học, đã có nhiều ứng dụng tiềm năng trong y sinh học và dược phẩm. Từ khóa - Hạt nano vàng, Dextran, Phương pháp hóa học.
ẢNH HƯỞNG CỦA QUÁ TRÌNH CHẾ BIẾN ĐẾN CHẤT LƯỢNG ĐỒ UỐNG GIÀU POLYPHENOL TỪ DỊCH CHIẾT LÁ ỔI
Authors: Tuyết Đặng Minh , Bảo Võ Văn Quốc 
Published: June 2019

Trong nghiên cứu này, chúng tôi khảo sát một số yếu tố như lượng đường, acid citric, ascorbic acid, carrageenan và lượng dịch chiết bổ sung ảnh hưởng đến quy trình sản xuất đồ uống, cũng như khảo sát thời gian thanh trùng để bảo quản sản phẩm. Mục đích của nghiên cứu này nhằm góp phần hoàn thiện quy trình sản xuất nước giải khát từ dịch chiết giàu polyphenol từ lá ổi non. Kết quả nghiên cứu cho thấy, chất lượng sản phẩm đạt tốt nhất khi bổ sung : 14% đường, 0,15% acid citric, 0,06% ascorbic acid, 0,03% carrageenan và lượng dịch chiết là 3%. Và thanh trùng sản phẩm ở 80°C trong thời gian 5 phút.
МОТИВАЦИЯ ТРУДОВЫХ РЕСУРСОВ в условиях цифровой экономики
Authors: Захаров Александр Николаевич , Зверева Ирина Альбертовна , Козлов Василий Александрович 
Published: June 2019

Предмет работы. Процессу воспроизводства трудовых ресурсов уделяют внимание во всех экономически развитых странах мира, поэтому проблема повышения эффективности формирования и использования трудовых ресурсов, безусловно, является актуальной. Статья посвящена новому подходу совершенствования и повышения эффективности мотивации в условиях современной экономики. Методология проведения работы. В условиях цифровой экономики к трудовым ресурсам предъявляются новые требования. Вместе с тем появляется проблема замены человека цифровыми средствами. На основании исследования демографической ситуации на селе и трудов ученых, занимающихся проблемами трудовых ресурсов, выявлена необходимость к преодолению «цифрового разрыва» и повышения качества трудовых ресурсов.
Результаты работы. Авторы отмечают необходимость рассматривать мотивацию как совокупный эффект усилий органов управления разных уровней и поведения человека в сложившихся экономических условиях. Выявлен накопительный или кумулятивный эффект мотивации, который позволит увеличить эффективность от применения системы мотивации в сельском хозяйстве на каждом организационно-экономическом уровне. Кумулятивный эффект оказывает концентрическое влияние на отдельные сельскохозяйственные организации и действует через умножение эффекта каждого уровня. Область применения результатов. Эффективность применения системы мотивации, складывающаяся на разных экономических уровнях, в конечном итоге повысит не просто экономическую эффективность воспроизводства трудовых ресурсов, но и эффективность экономики региона или страны в целом. Выводы. Намеченный руководством страны прорыв в эффективности сельского хозяйства, связанный с цифровизацией экономики и использованием новейших достижений генетики, робототехники, развитием инноваций, в конечном итоге зависит от компетенций и мотивации людей. Авторами сделан вывод на основе предложенного подхода к рассмотрению мотивации в новых экономических условиях для проблемы воспроизводства трудовых ресурсов сельского хозяйства, наметились пути ее решения.
Effect of Aslagh Capsule, a Traditional Compound Herbal Product on Oligomenorrhea in Patients with Polycystic Ovary Syndrome: A Three-Arm, Open-label, Randomized, Controlled Trial
Authors: Bahman Maryam , Hajimehdipoor Homa , Bioos Soodabeh , Hashem-Dabaghian Fataneh , Afrakhteh Maryam , Tansaz Mojgan 
Published: June 2019

Background: Oligomenorrhea is a common complaint in patients with polycystic ovary syndrome (PCOS). There are some useful medicinal recommendations such as Aslagh product (include fennel fruits, carrot seeds, chaste tree fruits) in Iranian traditional medicine for the treatment of oligomenorrhea in PCOS. Hence, the present investigation was designed to compare Aslagh capsule with metformin on the oligomenorrhea. Materials and Methods: One hundred fifty women aged between 18-43 years with oligomenorrhea due to PCOS were randomly divided into Aslagh, metformin, and Aslagh + metformin groups. The occurrence of menstrual bleeding was considered as the primary outcome. Menstrual cyclicity, duration, and volume of the bleeding were also evaluated. Results: Occurrence of menstrual bleeding was 87.2% in all patients, with no significant difference between the three groups (P> 0.05). Menstrual cyclicity significantly improved from baseline in Aslagh and Aslagh+ metformin groups (P=0.02). Duration of menstrual bleeding was significantly higher in Aslagh group in the first and the second menstrual bleeding cycle compared to the other two groups (P<0.05). No significant change was observed in the volume of the bleeding after the intervention in any of the three groups. The occurrence of menstrual bleeding in Aslagh group was significantly (P=0.03) higher than the other two groups in the fourth month (drug-free period). Conclusion: Aslagh capsule showed beneficial effects similar to metformin in the treatment of oligomenorrhea in PCOS women and could be suggested for use as an alternative treatment in these patients. [GMJ.2019;8:e1261]
A Short Review on the Relationships Between Nephrolithiasis and Myocardial Infarction
Authors: Karami Hormoz , Maleki Hadi , Baghbeheshti Maryam , Hashemi Mostafa , Rouzbeh Mehrdad , Afkhami Ardakani Mohammad 
Published: June 2019

The interaction between organs is a crucial part of modern medicine. As a very prerequisite to manage a disease, practitioners should have a full awareness of the related organs. Kidney and heart are two vital organs that are closely interconnected in various fields. These two organs have a lot of common risk factors for making a person unhealthy; therefore, if you prevent the disease in one of them, the other’s morbidity might be alleviated as well. Among them, nephrolithiasis and myocardial infarction (MI) have more risk factors in common, and both could be fatal. Also, these two diseases are important regarding the prevalence, incidence, and burden of disease. Some studies confirm the relationship between MI and nephrolithiasis; however, further researches are needed to discover the exact direction of their relationship. The present review aims to explain the mechanism of MI and nephrolithiasis; clarify the relationship between these two disease based on physiological, pathological, and clinical studies; and propose some solutions for the prevention and treatment of such diseases. [GMJ.2019;8:e1289]
Effects of eight weeks of bench press and squat power training on stable and unstable surfaces on 1RM and peak power in different testing conditions
Authors: Ignjatovic Aleksandar M. , Radovanovic Dragan S. , Kocić Jadranka 
Published: June 2019

BACKGROUND: The use of unstable training environments has been proposed to enhance the specific effects of movement through an increased activation of stabilizers and core muscles, but not for athletic or sport performance training requiring power. OBJECTIVE: The purpose of the study was to determine the effects in muscular strength and power outputs after eight weeks of stable and unstable resistance training in physically active subjects with maximal velocity of movement during concentric phase with the load of 50% of 1RM. METHODS: Seventy two male recreationally active subjects were divided into three groups (Unstable-UTG, Stable-STG and Control-CG). Unstable and Stable training groups trained twice a week for 8 weeks, bench press and squat exercises, 6 sets of 6 repetitions for each exercise. Pre and post-training measures included 1RM and peak power in stable and unstable conditions for bench press and squat. RESULTS: The results showed that there was a significant difference in main effects found with the training induced improvement between the training groups in pre- to post-test in squat 1RM, showing the transfer of specific unstable training exercises on 1RM squat. However, this was not the case in 1RM bench press. Both modalities (Stable and Unstable) produced statistically significant ([Formula: see text] 0.05) training effects on 1RM, with very small increases ranging from 3–7%. Significant main effects for peak power were found for bench press ([Formula: see text] 0.008) and squat ([Formula: see text] 0.025) exercises after the experimental program on both testing surfaces (stable and unstable). Both training programs produced greatest power gains on the surface on which the training was performed. The UTG improved significantly ([Formula: see text] 0.01) on peak power output on both the bench press and squat (12%) on unstable conditions. The STG improved significantly ([Formula: see text] 0.01) on peak power output on both the bench press and squat (7%) during stable conditions. CONCLUSION: The increase of 1RM in previously resistance untrained subjects is lesser than expected. The largest 1RM & peak power increases occurred after squat training on unstable surface, which suggests that unstable surface will not necessarily have negative effects on lower body performance.