bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Interpretation of Detection of IgM Anti-Brucella Antibody in the Absence of IgG and Vice Versa; a Diagnostic Challenge for Clinicians
Authors: JINDAN REEM AL , SALEEM NIDA , SHAFI AAMIR , AMJAD SHEIKH MUHAMMAD 
Published: March 2019

Abstract
Non-specific and often misleading clinical presentation of active brucellosis has made it a diagnostic puzzle for treating physicians. Clinicians rely greatly on the detection of IgG and IgM anti-Brucella antibodies by ELISA. Different patterns of positivity have been observed for IgG and IgM anti-Brucella antibodies in different cases, which further increases the risk of an erroneous diagnosis. Detailed herein is our two-years data with varied Brucella serology patterns and their clinical interpretation. Between January 2015 to December 2017, 1102 samples were processed in the Immunology Laboratory of KFHU for Brucella serology. 68 samples were positive for both IgG and IgM, 28 samples were positive for IgG and negative for IgM while 15 samples were positive for IgM and negative for IgG antibodies against Brucella. Electronic medical records, history of exposure, signs, symptoms, laboratory data, and the final diagnosis were recorded for all these patients. None of the patients with only positive IgM antibodies was finally diagnosed with brucellosis, while a diagnosis of brucellosis was established for only one patient with IgG antibodies positive in his serum. All the double-positive (IgG- and IgM-positive) serology patterns were diagnosed as having brucellosis. We concluded that determination of single IgM or IgG anti-Brucella-antibodies by ELISA could both be considered as definite and should ideally be interpreted in the context of appropriate clinical scenario and confirmation by other laboratory assays.
Biomechanics of the corneoscleral shell and hemodynamics of the glaucomatous eye: is there a connection?
Authors: Iomdina E. N. , Kiseleva O. A. , Bessmertny A. M. , Khoziev D. D. , Luzhnov P. V. , Shamaev D. M. , Moiseeva I. N. , Stein A. A. 
Published: March 2019

Purpose. To find the connection between the parameters of the corneoscleral shell and lamina cribrosa (LC) and hemodynamic parameters of the eyes with primary open angle glaucoma (POAG).Materials and methods. The study involved 111 eyes of 63 patients, including 41 eyes without ophthalmic pathology (control group, mean age M ± SD 66.9 ± 18.2 yrs), 22 eyes with the initial glaucoma stage (group 1, mean age 65.9 ± 11.3 yrs), 31 eyes with the developed glaucoma stage (group 2, mean age 69.2 ± 17.3 yrs), and 17 eyes with the advanced glaucoma stage (group 3, mean age 69,7 ± 7.3 yrs). LC parameters and the density of surface (SVL) and deep (DVL) vascular layers were measured using Spectralis OCT2 with an angiography module (Heidelberg Engineering, Germany) in the enhanced deep imaging (EDI) mode using AngioTool software. Corneal hysteresis (CH) and corneal resistance factor (CRF) were determined using ORA (Ocular Response Analyzer, Reichert, USA). The rigidity coefficient (E) of the corneoscleral shell was measured by a GlauTest-60 tonograph (Russia) operation in the differential tonometry mode. The elasticity coefficient (s) was determined by a modified differential tonometry technique. The rheographic index (RI) and pulse blood volume (PBV) were measured using transpalpebral rheoophthalmography.Results. A statistically significant correlation was revealed between CH and SVL (р = 0.005, r = 0.288), LC thickness and SVL and DVL (р = 0.001, r = 0.374 and р = 0.003, r = 0.397, respectively). A negative statistically significant correlation was found between E and RI (р = 0.000, r = -0.538) as well as between E and PBV (р = 0.001, r = -0.376). A similar correlation was revealed between s and theses parameters (RI and PBV; р = 0.027, r = -0.404 and р = 0.024, r = -0.410, respectively). E increase is accompanied by a decrease in the SVL density (р = 0.000, r = -0.376); besides, PBV is negatively correlated with the LC depth (р = 0.022, r = -0.257).Conclusion. In POAG, deteriorated blood supply of inner ocular shells (decreased RI, PBV, SVL and DVL density) correlates with (a) increased corneoscleral rigidity (manifested in the increase of rigidity and elasticity coefficients, and the decrease of CH), and (b) decreased LC thickness and its increased depth. Increased rigidity of the corneoscleral shell contributes to an LC posterior displacement. It must be concluded that LC thickness is a more sensitive biomechanical parameter that changes even in the initial stages of POAG and has a high diagnostic value.
Effectiveness of Seydana oil in combination treatment of herpetic endothelial keratitis
Authors: Gulieva M. G. 
Published: March 2019

Purpose: to study the effectiveness of seydana (black cumin) oil in combined treatment of herpetic endothelial keratitis. Material and methods. The study included 68 patients (68 eyes) with herpetic endothelial keratitis, developed after cataract surgery. 35 men and 33 women aged 39 to 73 (58.3 ± 8.9) years were divided into two equal groups. The main group (34 patients, 34 eyes) received conventional treatment supplemented with black cumin oil, while the comparison group of 34 patients (34 eyes) received conventional treatment alone.Results. Cornea infiltration in the main group resorbed sooner than in the comparison group (18.43 ± 0.3 days and 23.2 ± 0.5 days respectively; p < 0.05). The treatment lasted shorter in the main group compared with the comparison group (22.1 ± 0.1 days vs. 25.2 ± 0.3 days; p < 0.05). Complete epithelialization was averagely noted on the 19th to the 21st day of treatment (respectively, 19.6 ± 0.9 and of 21.12 ± 0.6; p > 0.05). Visual acuity improved to achieve, respectively, 0.51 ± 0.24 and 0.44 ± 0.17 (p > 0.05).Conclusion. The patients who received seydana oil in addition to conventional treatment showed a significantly higher therapeutic effect in some parameters (resorption time of corneal infiltration and duration of treatment) than the comparison group.
Retinal and choroidal morphological changes in Huntington's disease
Authors: Svetozarskiy S. N. , Kopishinskaya S. V. , Smetankin I. G. 
Published: March 2019

Purpose: to investigate the choroidal and retinal morphology in Huntington's disease (HD) using optical coherence tomography (OCT) and to analyze how the parameters studied correlate with the clinical data.Material and methods. The study included two groups of subjects, (1) 44 HD patients, averagely aged 37.6 ± 10.2 yrs, and (2) 31 healthy volunteers, averagely aged 37.3 ± 10.8 yrs. The groups had matching age, sex distribution, intraocular pressure and mean refractive error. In the study group, 21 patients had pre-manifest and 23, manifest HD stage. All patients underwent a thorough neurological and ophthalmic examination which included retinal OCT. The foveal choroidal thickness, retinal thickness in 9 areas of the macular zone, retinal ganglion cells complex (GCC) and peripapillary retinal nerve fiber layer thickness (RNFL) were evaluated in 4 quadrants. CAG repeat expansion size (cytosine-adenine-guanine) in the huntingtin gene, the disease duration and Unified HD Rating Scale motor scores (UHDRS) were evaluated for HD patients.Results. The range of the CAG repeat expansion size in the study group was 37–56 repeats (44.3 ± 3.8), the UHDRS motor score was 36.3 ± 29.7, disease duration was 13.7 ± 7.2 years. OCT revealed a significant decrease in the foveal choroidal thickness, GCC complex thickness, average, temporal, inferior and nasal RNFL thickness and total retinal thickness in the external temporal area in HD patients as compared to the controls. In addition, an inverse correlation between the disease duration, UHDRS Motor Score and a number of OCT parameters was found.Conclusion. The results confirm the promising potential of retinal tomographic parameters as a biomarker for early diagnosis and monitoring of the neurodegenerative process progression. The topography of retinal thickness reduction indicates a specific pattern of retinal neurodegeneration in HD.
Plant based chemical admixtures – potentials and effects on the performance of cementitious materials
Authors: Schmidt Wolfram , Tchetgnia Ngassam Ines Leana , Olonade Kolawole Adisa , Mbugua Rose Njeri , Kühne Hans-Carsten 
Published: March 2019

While today, engineers can choose from a wide range of rheology modifying admixtures, in some parts of the world, these are difficult to access, due to their complex processing. However, alternatives can be bio-based polymers such as polysaccharides from various sources. These are easily accessible all over the world, do not demand for complicated processing, and typically they are more sustainable than many established materials, which are crude oil-based.
The paper presents the effects of acacia gum, cassava starch and the gum of triumfetta pendrata A. Rich on the rheological performance of cementitious systems. It is shown that acacia gum can be as efficient as polycarboxylate based superplasticisers, cassava starch can reduce the yield stress slightly with little effect on the plastic viscosity, and the gum of triumfetta pendrata A. Rich increases the thixotropy of cement pastes with plasticizing polymers significantly.
Особенности цитопротекции слизистой оболочки желудка и двенадцатиперстной кишки у подростков с хроническим гастродуоденитом на фоне пищевой гиперчувствительности
Authors: Berezenko V.S. , Krotevich M.S. , Bogdanova T.A. , Zamula V.V. , Kozynkevych H.E. 
Published: March 2019

Актуальность. В наше время остаются недостаточно изученными цитопротективные свойства желудочно-кишечного тракта у детей с хроническим гастродуоденитом на фоне пищевой гиперчувствительности. Целью нашего исследования стало оценить состояние цитопротективного потенциала слизистых оболочек (СО) желудка и двенадцатиперстной кишки у подростков с хроническим гастродуоденитом на фоне пищевой гиперчувствительности путем определения уровня трефоилового фактора 1 (TFF-1) в слизистой оболочке желудка и TFF-2 слизистой оболочки желудка и двенадцатиперстной кишки иммуногистохимическим методом. Материалы и методы. Исследование проведено 50 подросткам (от 12 до 17 лет), из которых в I группе было 64 % (n = 32) с хроническим гастродуоденитом на фоне пищевой гиперчувствительности, во II группе — 36 % (n = 18) детей с хроническим гастродуоденитом без пищевой гиперчувствительности. Всем детям выполнено морфологическое и иммуногистохимическое исследование биоптатов с определением TFF-1 и TFF-2. Оценка экспрессии ­TFF-1 и TFF-2 пептидов проводилась по балльной шкале по количеству окрашенных клеток эпителия желез антрального отдела и бокаловидных клеток в поле зрения при увеличении в 40 раз: 0 баллов — отсутствует окрас, 1 балл — 30 % окрашенных клеток, 2 балла — 30–70 % окрашенных клеток, 3 балла — 70–100 % окрашенных клеток. Результаты. Выраженная экспрессия TFF-1 (3 балла) в слизистой желудка имела место у подростков обеих групп. По результатам проведенного исследования, у 62,5 % (n = 20) детей первой группы и у 22 % (n = 4) подростков II группы в СО двенадцатиперстной кишки отсутствовала окраска бокаловидных клеток (0 баллов) (c2 = 7,5; p = 0,008). Слабая экспрессия (1 балл) имела место у 34,5 % (n = 11) детей I группы и у 67 % (n = 12) детей II группы (c2 = 4,84; p = 0,03). По результатам статистического анализа группа детей с пищевой гиперчувствительностью имеет в 17 раз выше шансы на возникновение атрофических изменений слизистой двенадцатиперстной кишки. Выводы. У детей с пищевой гиперчувствительностью снижены цитопротективные свойства слизистой оболочки двенадцатиперстной кишки, о чем свидетельствует отсутствие экспрессии TFF-2 пептида. Также достоверно чаще возникают микроэрозии, уменьшение количества крипт и бруннеровых желез в СО двенадцатиперстной кишки в группе детей с пищевой гиперчувствительностью при отсутствии или слабой экспрессии TFF-2 пептида (р < 0,05).
Вплив гіпотиреозу в чоловіків на андрогенну функцію
Authors: Krytskyi T.I. 
Published: March 2019

Актуальність. Результати сучасних досліджень вказують на роль тиреоїдних гормонів, метаболічного дисбалансу, психічного стресу в підтриманні загального й гормонального гомеостазу організму. У той же час взаємодія тиреоїдних і статевих гормонів при гіпотиреозі в чоловіків залишається предметом дискусій. Мета: вивчити частоту клінічних і лабораторних ознак андрогенного дефіциту, а також вплив недостатнього рівня тиреоїдних гормонів на андрогенну функцію в чоловіків із гіпотиреозом. Матеріали та методи. Під спостереженням перебувало 55 чоловіків із первинним гіпотиреозом віком від 36 до 60 років, а також 25 практично здорових чоловіків. Результати. У хворих на гіпотиреоз спостерігалося вірогідне зниження вмісту глобуліну, що зв’язує статеві гормони (ГЗСГ), загального тестостерону, а також вільного й біодоступного тестостерону порівняно зі здоровими чоловіками. У хворих на гіпотиреоз сироваткова концентрація вільного тироксину позитивно корелює із ГЗСГ. Виявлені негативні кореляції середнього ступеня вираженості між ГЗСГ і вільним і біодоступним тестостероном. Висновки. У чоловіків середнього віку з гіпотиреозом рекомендується визначення вмісту андрогенів в крові для виявлення синдрому андрогенного дефіциту.
Bel Fıtığı Ameliyatı Olan Hastalarda Ağrı ve Korku-Kaçınma Davranışları
Authors: KÖÇKAR Çiğdem , TAN ÇELİK Fatma 
Published: March 2019

Amaç:
Bel fıtığı ameliyatı
gibi yaşam tarzı değişikliği gerektiren ameliyatlardan sonra hastalar ağrı ve
komplikasyon nedeniyle kaçınma davranışı geliştirebilmektedirler. Kaçınma
davranışı hareket oranını azaltarak iyileşmeyi geciktirebilmekte ve
komplikasyonlar oluşmasına neden olabilmektedir. Bu araştırmanın amacı bel fıtığı
ameliyatı olan hastaların ağrı ve korku kaçınma düzeylerinin belirlenmesidir.

Materyal-Metod:
Araştırma Kasım 2016-
Mayıs 2017 tarihleri arasında, 92 hastayla, tanımlayıcı olarak yapıldı.
Araştırmanın verileri Sosyo-demografik özellikler formu, Korku Kaçınma
Tutumları Ölçeği ve Görsel Ağrı Skalası kullanılarak toplandı.

Bulgular:
Araştırmaya katılan
hastaların yaş ortalaması 46.38±12.99
bulundu. Araştırma sonucunda kadınların erkeklere göre daha fazla korku kaçınma
yaşadığı ve kadınların cinsiyet ile ağrı arasındaki farkın anlamlı olduğu
saptandı (p&lt;0.01). Araştırmaya katılan ve bedensel aktivite gerektiren
hastaların korku kaçınma oranlarının diğer hastalara göre daha fazla olduğu
bulundu. Hastaların meslekleri ile mesleki iş kaynaklı korku kaçınma puan
ortalamaları arasındaki farkın anlamlı olduğu bulundu (p&lt;0.05). Ağrı
ile korku kaçınma davranışları arasındaki ilişki incelendiğinde ağrının en
fazla fiziksel aktivite kaynaklı korku kaçınma ile ilişkisi vardı. Ağrı ile
korku kaçınma toplam ve alt boyutları arasındaki ilişkinin anlamlı olmadığı
saptandı.

Sonuç: Araştırma sonucunda kadınların korku
kaçınma ve ağrı düzeylerinin daha yüksek olduğu bulundu. Bedensel aktivite gerektiren işlerde çalışan
hastaların korku kaçınma davranışlarının daha fazlaydı. Ağrı ile fiziksel aktivite
kaynaklı korku kaçınma davranışı arasındaki ilişkinin yüksek olduğu saptandı.
Epidural Doğum ve Normal Doğumda Müdahale Oranları ve Müdahaleye Bağlı Gelişen Komplikasyonların Karşılaştırılması
Authors: ÖZ İsa Şükrü 
Published: March 2019

Amaç: Epidural analjezi uygulanarak
gerçekleşen normal doğum ile epidural analjezi uygulanmadan gerçekleşen normal
doğum arasındaki müdahale oranları ve müdahaleye bağlı gelişen
komplikasyonların karşılaştırılması

Materyal-Metot: Çalışmaya Haziran 2017 ile Temmuz
2018 arası zaman diliminde hastanemize doğum için başvuran gebeler dahil
edildi. Baş prezantasyon dışında prezantasyonu olanlar, çoğul gebelikler ve
herhangi bir sebepten sezaryen ihtiyacı olanlar çalışmaya dahil edilmedi.
Müdahale açısından gebeler, normal doğum yapanlar ve epidural normal doğum
yapanlar olmak üzere iki gruba ayrıldı. Gebelerin yaş, gravida, parite, gebelik
süreleri, müdahale varlığı, müdahale komplikasyonu ve müdahale şekli kayıt
altına alındı ve gruplar arasındaki farkları belirlemek
amacıyla karşılaştırmalar yapıldı. Değişkenler arası karşılaştırmalar Mann
Whitney U ve Pearson Ki-kare testi ile yapıldı.

Bulgular: Epidural anestezi uygulanarak doğum yapan
vakalarda, epidural anestezi uygulanmadan gerçekleşen doğumlara göre yaş,
gravida ve parite ortalamalarının daha düşük olması istatistiksel olarak
anlamlıdır (p&lt;0,05). Epidural anestezi uygulanarak doğum yapan vakalarda,
epidural anestezi uygulanmadan gerçekleşen doğumlara göre daha fazla oranda
müdahale ihtiyacının görülmesi istatistiksel olarak anlamlıdır (p&lt;0,05). Epidural anestezi uygulanarak doğum yapan vakalarda, epidural anestezi
uygulanmadan gerçekleşen doğumlara göre daha fazla oranda müdahale
komplikasyonu görülmesi istatistiksel olarak anlamlıdır (p&lt;0,05).

Sonuç: Epidural doğumda normal doğuma göre
müdahale oranı ve müdahale komplikasyonu oranı daha yüksektir. Müdahale ve
komplikasyonlar özellikle ilk doğumu olan gebelerde daha fazla görülmüştür. Doğum
eylemi başladıktan sonra sezeryana gitme oranları arasında istatistiksel olarak
anlamlı bir fark yoktur. Epidural doğumu normal doğuma göre daha genç nesil
tercih etmektedir.

Anahtar Kelimeler:
Epidural Doğum, Enstrümental Doğum,
Epidural Komplikasyon
Ödemin Değerlendirilmesinde Yüz Tarama Sistemi ile Pletismografik Ölçüm Yönteminin Karşılaştırılması
Authors: ULU Murat , AKÇAY Hüseyin 
Published: March 2019

Amaç: Gömülü
dişlerin çekimi çene cerrahisi alanında en sık yapılan işlemlerden biridir ve
işlem sonrası trismus, ağrı ve ödem meydana gelebilmektedir. Bu çalışmada gömülü
üçüncü molar dişlerin çekimi sonrasında oluşan ödemin değerlendirilmesinde 3
boyutlu ölçüm yöntemi ile konvansiyonel yöntemlerden biri olan esnek cetvelle
yapılan pletismografik ölçüm yönteminin
kıyaslanarak değerlendirilmesi amaçlanmıştır.

Materyal ve metot: Çalışmaya
alt çenesinde bilateral, gömülü diş çekimi endikasyonu koyulmuş 18 yaş ve
üzerinde 60 hasta dahil edildi. Hastalar iki farklı gruba ayrıldı, çekim
sonrası hastaların yüzünün bir tarafına kinesio bant yapıştırılırken (KB grubu,
n:60) ; karşıt tarafta yapılan diş
çekimi sonrası hastalara herhangi bir uygulama yapılmadı (kontrol grubu, n:60).
Ameliyattan hemen önce (T0), sonrası 2.(T1) ve 7.(T2) günlerde ödem ölçümleri
3dMD ve pletismografik yöntemlerle ayrı ayrı gerçekleştirildi.

Bulgular: Elde
edilen sonuçlara göre; T0-T1; T0-T2 zaman aralığında meydana gelen ödemin değerlendirilmesinde
3dMD ölçüm yötemi ile pletismografik ölçüm yöntemi arasında istatistiksel
olarak anlamlı bir korelasyon tespit edilmemişir (p&gt;0,05).

Sonuç: Maksillofasiyal
bölgede yapılan cerrahi müdahalelerden sonra yumuşak dokuda meydana gelen
hacimsel değişikliklerin değerlendirilmesinde, dokuya doğrudan temas etmeden ölçüm
yapılabilmesine olanak tanıdığı için 3D tarama sistemlerinin daha güvenilir
sonuçlar verdiği düşünülmektedir.
Evaluation of the effects of zinc supplementation on the symptoms and duration of the disease in acute viral gastroenteritis
Authors: EL Cigdem , CELİKKAYA Mehmet Emin 
Published: March 2019

Introduction: Acute viral
gastroenteritis is the second most common cause of high morbidity and mortality
in childhood. Viral gastroenteritis is the most common cause of severe diarrhea
and associated hospitalizations especially in toddlers. It has been shown that
the administration of 20 mg of zinc daily during acute diarrhea reduces the
duration of watery diarrhea by 25% and it has been reported to have protective
and therapeutic effects in the acute period. The aim of this study is to
retrospectively determine the beneficial effects of oral zinc supplementation
on the severity and duration of complaints of toddlers who were treated in our
clinic with the diagnosis of acute viral gastroenteritis.Methods: Toddlers who were hospitalized
in the Department of Pediatrics for acute viral gastroenteritis between October
2016 and March 2018 were included in the study. The study was retrospective and
the data of the patients were obtained from the patient files. The diagnosis of
acute viral gastroenteritis was made by detecting the adenovirus-rotavirus
antigen in the fresh stool specimens. The patients were divided into two
groups. Group 1: patients who received zinc supplementation in addition to
support treatment. Group 2: patients who received only supportive therapy.Results: The mean number of vomiting was
3.60 / day and watery diarrhea was 5.20 / day in group-1 while number of
vomiting was 6.1 / day and watery diarrhea was 8.9 / day in group-2 in the 36th
hour during treatment. The tolerability of oral feeding at 36 th hour was
49.39% ( 41) in group-1 and 45.07% (32) in group-2. The mean number of vomiting
and watery diarrhea in group-1 cases at 72th hours was 1.2 / day and 4.30 /
day, while in group-2 cases, 3.90 / day and 7.20 / day.

Conclusions: Although the physiopathology of the effects of zinc on gastroenteritis
is not yet fully understood, diarrhea is seen both as a cause and as a result
of zinc deficiency. The fact that
patients with gastroenteritis benefit from zinc support suggests that zinc
enhances this effect by increasing intestinal immunity.
Reliability of 3D dental and skeletal landmarks on CBCT images
Authors: Park Joorok , Baumrind Sheldon , Curry Sean , Carlson Sean K. , Boyd Robert L. , Oh Heesoo 
Published: March 2019

ABSTRACT

Objectives:
To quantify reliability of three-dimensional skeletal landmarks and a comprehensive set of dental landmarks in cone-beam computed tomography (CBCT) and to determine the shapes of envelope of error.

Materials and Methods:
Three judges located 31 skeletal landmarks and 60 dental landmarks on the pre- and posttreatment CBCT images of 22 patients. Landmark error was determined by calculating the distance of deviation of landmark locations around their average. Standard deviation and mean radial spherical error were calculated. Scatterplots were constructed to characterize envelope of error.

Results:
The midline landmarks of the cranial base were highly reliable. Bilateral skeletal landmarks tended to have larger error than midline landmarks. Among the nonconventional landmarks, fronto-zygomatic suture, condyle, and mental foramen showed relatively high reliability. However, foramen spinosum and temporal fossa showed larger errors. Gonion was the least reliable landmark. Most dental landmarks were located more reliably than skeletal landmarks. The highest reliability was found at incisal edges. Mesiobuccal cusp of first molars also showed high reliability.

Conclusions:
There were differences in the size and shape of the distributions of errors of different landmarks. Most landmarks showed elongated envelopes. Bilateral structures tended to show greater errors than midline structures. Most dental landmarks were more reliable than skeletal landmarks.
Meningkatkan Minat & Hasil Belajar Siswa dalam Berkomunikasi Bahasa Inggris melalui Metode Role Play pada Mata Pelajaran Memproses Reservasi Siswa
Authors: Suardani Luh 
Published: March 2019

Tujuan dari diadakannya penelitian ini adalah untuk mengetahui peningkatan minat dan hasil belajar siswa pada mata pelajaran memproses reservasi dalam berkomunikasi bahasa Inggris pada mata pelajaran memproses reservasi siswa kelas XI AP 2 semester ganjil SMK Negeri 2 Singaraja Tahun Pelajaran 2017/2018 setelah diterapkannya metode role play. Penelitian ini adalah penelitian tindakan kelas (PTK). Subjek dalam penelitian tindakan kelas ini adalah siswa kelas XI AP 2 semester ganjil SMK Negeri 2 Singaraja Tahun Pelajaran 2017/2018 yang berjumlah 34 orang. Sedangkan objeknya adalah minat belajar dan hasil belajar siswa. Data minat belajar siswa dikumpulkan dengan lembar observasi, sedangkan data hasil belajar siswa dikumpulkan dengan tes unjuk kerja. Analisis data yang digunakan pada penelitian ini menggunakan analisis data deskriptif. Berdasarkan penelitian yang telah dilakukan dapat disimpulkan bahwa penerapan metode Role Play dapat meningkatkan minat dan hasil belajar siswa pada mata pelajaran memproses reservasi dalam berkomunikasi bahasa Inggris pada mata pelajaran memproses reservasi siswa kelas XI AP 2 semester ganjil SMK Negeri 2 Singaraja Tahun Pelajaran 2017/2018