bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inventory ordering policies for mixed sale of products under inspection policy, multiple prepayment, partial trade credit, payments linked to order quantity and full backordering
Authors: Taleizadeh Ata Allah , Tavassoli Sara , Bhattacharya Arijit 
Published: September 2019

Abstract
The situation where serviceable products are sold together with a proportion of deteriorating products to consumers is rarely discussed in the literature. This article proposes an inventory model with disparate inventory ordering policies under a situation where a portion of serviceable products and a portion of deteriorating products are sold together to consumers (i.e. mixed sales). The ordering policies consider a hybrid payment strategy with multiple prepayment and partial trade credit schemes linked to order quantity under situations where no inventory shortage is allowed and inventory shortage is allowed with full backorder. The hybrid payment policy offered by a supplier is introduced into the classical economic ordering quantity model to investigate the optimal inventory cycle and the fraction of demand that is filled from the deteriorating products under inspection policy. Further, a new solution method is proposed that identifies optimal annual total profit with mixed sales assuming no inventory shortage and inventory shortage with full backorder. The impact of an inspection policy is investigated on the optimality of the solution under hybrid payment strategies for the deteriorating products. The validation of the proposed model and its solution method is demonstrated through several numerical examples. The results indicate that the inventory model along with the solution method provide a powerful tool to the retail managers under real-world situations. Results demonstrate that it is essential for the managers to consider inclusion of an inspection policy in the mixed sales of products, as the inspection policy significantly increases the net annual profit.
Research-based PAM50 signature and long-term breast cancer survival
Authors: Pu Minya , Messer Karen , Davies Sherri R. , Vickery Tammi L. , Pittman Emily , Parker Barbara A. , Ellis Matthew J. , Flatt Shirley W. , Marinac Catherine R. , Nelson Sandahl H. , Mardis Elaine R. , Pierce John P. , Natarajan Loki 
Published: September 2019

Abstract

Purpose
Multi-gene signatures provide biological insight and risk stratification in breast cancer. Intrinsic molecular subtypes defined by mRNA expression of 50 genes (PAM50) are prognostic in hormone-receptor positive postmenopausal breast cancer. Yet, for 25–40% in the PAM50 intermediate risk group, long-term risk remains uncertain. Our study aimed to (i) test the long-term prognostic value of the PAM50 signature in pre- and post-menopausal breast cancer; (ii) investigate if the PAM50 model could be improved by addition of other mRNAs implicated in oncogenesis.

Methods
We used archived FFPE samples from 1723 breast cancer survivors; high quality reads were obtained on 1253 samples. Transcript expression was quantified using a custom codeset with probes for > 100 targets. Cox models assessed gene signatures for breast cancer relapse and survival.

Results
Over 15 + years of follow-up, PAM50 subtypes were (P < 0.01) associated with breast cancer outcomes after accounting for tumor stage, grade and age at diagnosis. Results did not differ by menopausal status at diagnosis. Women with Luminal B (versus Luminal A) subtype had a > 60% higher hazard. Addition of a 13-gene hypoxia signature improved prognostication with > 40% higher hazard in the highest vs lowest hypoxia tertiles.

Conclusions
PAM50 intrinsic subtypes were independently prognostic for long-term breast cancer survival, irrespective of menopausal status. Addition of hypoxia signatures improved risk prediction. If replicated, incorporating the 13-gene hypoxia signature into the existing PAM50 risk assessment tool, may refine risk stratification and further clarify treatment for breast cancer.
Correlation between patency and clinical improvement after lymphaticovenous anastomosis (LVA) in breast cancer-related lymphedema: 12-month follow-up
Authors: Wolfs Joost A. G. N. , de Joode Luuke G. E. H. , van der Hulst René R. W. J. , Qiu Shan S. 
Published: September 2019

Abstract

Purpose
Breast cancer-related lymphedema (BCRL) is caused by an interruption of the lymphatic system after breast cancer treatment. Lymphaticovenous anastomosis (LVA), by which one or more patent lymphatic collecting vessels are connected to subcutaneous veins, shows promising results. Postoperatively, the patency of these anastomosis can be evaluated; however, little is known concerning the long-term patency after LVA in patients with BCRL. The aim of this study was to analyse the long-term patency, quality of life (QoL) and arm circumference after LVA, and to explore differences between patent and non-patent anastomosis and its correlation with clinical improvement.

Methods
Twenty-five patients underwent indocyanine green (ICG) lymphography, lymph ICF-questionnaire, and arm circumference measurement preoperatively and 12 months after the LVA procedure.

Results
Seventy-six percent of the patients showed at least one patent anastomosis after 12 months. Quality of life according to the Lymph-ICF increased significantly (p < 0.000); however, arm circumference showed no significant decrease. Sixty-five percent discontinued wearing compression stockings. The patent anastomosis group, compared with the non-patent anastomosis group showed, without significance, more improvement in QoL, arm circumference, and discontinuation of compression stockings, as well as a lower rate of infections both pre- and postoperatively, a shorter duration of lymphedema preoperatively, and a higher rate of early lymphedema and ICG stage.

Conclusions
LVA showed an acceptable patency and positive correlation between a patent anastomosis and clinical improvement after 12 months. Further research with a larger study population is required to determine whether outcomes or patient characteristics significantly correlate with a patent anastomosis after LVA operation.
The wage premium from foreign language skills
Authors: Liwiński Jacek 
Published: September 2019

Abstract
The globalisation of labour markets makes language skills one of the key competences required by employers nowadays. The purpose of this paper is to estimate the wage premium from the foreign language skills earned by Poles. Poles seem to be a good case study, because the Polish language is not used for international communication and as many as 58% of Poles command at least one foreign language. I use data from three waves (2012–2014) of the Human Capital Balance survey with a pooled sample of about 35,000 individuals. I estimate a wage equation with the Heckman correction for selection to employment and I check for robustness with propensity score matching. I find that the advanced command of a foreign language yields a wage premium of 11% on average. Interestingly, I find a much higher wage premium from proficiency in Spanish (32%), French (22%) or Italian (15%) than from proficiency in English (11%) or German (12%).
Application of cyanated asphaltenes in gas-phase adsorption processes for removal of volatile organic compounds
Authors: Plata-Gryl Maksymilian , Momotko Malwina , Makowiec Sławomir , Boczkaj Grzegorz 
Published: September 2019

Abstract
The paper presents an innovative, chemically modified (methylcyanated) asphaltene-based adsorbent that can be an interesting low-cost alternative for traditional adsorbents. Adsorption properties of adsorbents were examined by inverse gas chromatography technique, adsorption isotherms, and breakthrough curves. A significant increase in retention volume for pyridine, 2-pentanone, nitropropane, toluene, and 1-butanol was observed. Rohrschneider–McReynolds constants revealed an increase in strength of interactions as a result of the modification, especially in strong proton–acceptor interaction (by a factor of 4.6). The surface-free energy of asphaltene adsorbents increased from 136.71 to 169.95 mJ m−2 after modification. It is similar to the surface-free energy of silica or alumina. Moreover, modified adsorbent shows very high adsorption potential for pyridine. Adsorption isotherms revealed that monolayer adsorption capacity for pyridine increased 1.5 times after modification. Breakthrough curves of pyridine indicate that chemical modification increased the adsorption capacity, removal efficiency, and throughput. Scale-up calculations revealed that adsorption column packed with modified asphaltene adsorbent would be almost two times smaller compared to a column packed with unmodified one.

Graphic abstract
Application of CFD technique to simulate enhanced oil recovery processes: current status and future opportunities
Authors: Jafari Arezou , Hasani Mohammadreza , Hosseini Mostafa , Gharibshahi Reza 
Published: September 2019

Abstract
Nowadays, because of the reduction in oil resources and the passage of the first and second life period of current reservoirs, using enhanced oil recovery (EOR) methods is of great importance. In recent years, due to the developments in technology and the advent of powerful computers, using simulation methods in enhanced oil recovery processes is on the rise. The computational fluid dynamics (CFD) method, as a branch of fluid mechanics, is a suitable method for studying and simulating EOR methods. In this study, a review was done on the application of CFD studies for simulating EOR methods. Also, potentials for future studies and the challenges researchers may face in this method were mentioned. Although using this method in enhanced oil recovery processes has recently started, different areas for more studies still exist. To optimize the usage of this method in future studies, the necessity of multiphase models and solution methods development, as well as considering all microscopic parameters such as interfacial tension and viscosity in investigating oil recovery factor is of great importance.
Extracorporeal Shock Waves Therapy Delivered by Aries Improves Erectile Dysfunction in Spontaneously Hypertensive Rats Through Penile Tissue Remodeling and Neovascularization
Authors: Assaly Rana , Giuliano François , Clement Pierre , Laurin Miguel , Favier Maryline , Teo Pearline , Bernabe Jacques , Alexandre Laurent , Behr-Roussel Delphine 
Published: September 2019

AbstractBackgroundLow-intensity extracorporeal shock wave therapy (Li-ESWT) has been reported to improve erectile function in patients with moderate-to-severe erectile dysfunction (ED) or even convert phosphodiesterase type 5 inhibitors nonresponders to responders. ED is highly prevalent in hypertensive patients. The effect of Li-ESWT on an animal model of hypertension-associated ED has not been reported.AimTo investigate the effect of Li-ESWT on hypertension-associated ED and provide plausible mechanisms of action of Li-ESWT on local mechanisms of penile erection.MethodsSpontaneously hypertensive rats (SHRs) in the active group (n = 13) received Li-ESWT at energy flux density 0.06 mJ/mm2 (Aries; Dornier MedTech, Wessling, Germany) twice weekly for 6 weeks. The emitter was set to zero for SHRs in the sham group (n = 12). Erectile function was assessed 4 weeks post-treatment by monitoring intracavernosal pressure (ICP) in response to electrical stimulation of cavernous nerve before and after single dose of 0.3 mg/kg intravenous sildenafil. Cavernosal tissue was then evaluated for collagen/smooth muscle content, neuronal nitric oxide synthase (nNOS), and vascular endothelial factor (CD31) expression.OutcomesErectile function was assessed with ICP, erectile tissue remodeling was studied by smooth muscle/collagen ratio, nNOS and CD31 were semiquantitatively evaluated on cavernosal sections.ResultsThe improvement of ICP parameters was greater in Li-ESWT–treated rats compared with controls with and without sildenafil. Sildenafil led to 20% increase in area under the intracavernosal pressure curve measured during the entire response/mean arterial pressure at 10 Hz in ESWT_SHR + sildenafil compared with ESWT_SHR. The smooth muscle/collagen ratio increased 2.5-fold in Li-ESWT compared with sham. Expression of CD31 tended to be increased whereas nNOS was unchanged.ConclusionsLi-ESWT by Aries may represent an effective noninvasive therapeutic alternative and a relevant add-on therapy to phosphodiesterase type 5 inhibitors for ED in hypertensive patients, and it is suggested that it acts via remodeling of the penile tissue and promoting cavernosal vascularization.
Circular RNA Expression Profiles in Vaginal Epithelial Tissue of Women With Lubrication Disorders
Authors: Zhang Jingjing , Xia Haiping , Zhang Aixia , Zhu Yuan , Pan Lianjun , Gu Ping , Ma Jiehua 
Published: September 2019

AbstractIntroductionRecently, circular RNA (circRNA) has been proved to occupy a vital pathological position in many diseases by acting as microRNAs sponges. However, the role of circRNA in female sexual dysfunction (FSD), especially in lubrication disorders (LDs), remains unclear.AimThe aim of this study was to detect circRNA expression in LDs, analyzed target genes, and pathways regulated by the differently expressed circRNAs.MethodsIn this study, next-generation sequencing was first conducted to produce circRNA expression profiles of FSD groups and normal control groups. Furthermore, differences in expression of 6 randomly selected circRNAs were confirmed through real-time quantitative polymerase chain reaction. Kyoto Encyclopedia of Genes and Genomes biological pathway analysis and Gene Ontology showed that immune processes and infection could be involved in the development of FSDs.Main Outcome MeasureCircRNA expression in vaginal epithelial tissue obtained from women with LDs have been detected. Gene Ontology, Kyoto Encyclopedia of Genes and Genomes biological pathway analysis, and circRNA-microRNA interaction predictions were investigated.ResultsTotally, 7,746 circRNAs of vaginal epithelial tissue from women of 2 groups were sequenced. Preliminary judgment revealed that there were 73 circRNAs that have significant differential expression, including 53 downregulated circRNAs and 20 upregulated circRNAs. Research results also displayed that the majority of circRNAs has multiple binding sites of microRNAs, including miR-137, which has been reported to be linked to FSD.Clinical ImplicationsWe predicted 10 circRNAs paired with hsa-miR-137-5p, but the mechanism of circRNA involvement in disease development remains to be further explored.Strengths & LimitationsFor the first time, the research disclosed the potential pathogenesis of LDs. However, we only analyzed the expression profile of circRNA in FSD, no specific mechanism was further confirmed or proposed. We still have a preliminary understanding, and more research is needed to explore the target of FSD treatment.ConclusionThe results suggest that circRNAs have different expression in the FSD groups and play a vital part in the occurrence and development of FSD.
Transitivity correlation: A descriptive measure of network transitivity
Authors: Dekker David , Krackhardt David , Snijders Tom A. B. 
Published: September 2019

AbstractThis paper proposes that common measures for network transitivity, based on the enumeration of transitive triples, do not reflect the theoretical statements about transitivity they aim to describe. These statements are often formulated as comparative conditional probabilities, but these are not directly reflected by simple functions of enumerations. We think that a better approach is obtained by considering the probability of a tie between two randomly drawn nodes, conditional on selected features of the network. Two measures of transitivity based on correlation coefficients between the existence of a tie and the existence, or the number, of two-paths between the nodes are developed, and called “Transitivity Phi” and “Transitivity Correlation.” Some desirable properties for these measures are studied and compared to existing clustering coefficients, in both random (Erdös–Renyi) and in stylized networks (windmills). Furthermore, it is shown that in a directed graph, under the condition of zero Transitivity Correlation, the total number of transitive triples is determined by four underlying features: size, density, reciprocity, and the covariance between in- and outdegrees. Also, it is demonstrated that plotting conditional probability of ties, given the number of two-paths, provides valuable insights into empirical regularities and irregularities of transitivity patterns.
Written training tasks are better than oral training tasks at improving L2 learners’ speech production
Authors: Solier Clara , Perret Cyril , Baqué Lorraine , Soum-Favaro Christiane 
Published: September 2019

AbstractThis study examined the effect of written input on the production of word-final vowels (oral: /i/, /e/; nasal: /ɑ̃/, /ɔ̃/) by 100 native Moroccan learners of French as a second language, relying on a pretest/posttest paradigm. During pretest, participants performed a word repetition task. Then, participants were assigned to five experimental (training) conditions, varying in the modality of stimulus presentation (oral vs. written) and in the modality of response (oral vs. written), before their oral production of the word-final vowels was evaluated in the posttest. Results clearly showed that posttest pronunciation accuracy was affected by the presence of orthographic information in the training task. The copy training task was the most efficient at improving posttest accuracy. Results indicate that orthography, and more specifically the written production copy task, helps L2 learners’ pronunciation more efficiently than phonetic correction.
GLOBAL GOODS, SILVER AND MARKET INTEGRATION: CONSUMPTION OF WINE, SILK AND PORCELAIN THROUGH THE GRILL COMPANY VIA MACAO-CANTON AND MARSEILLE-SEVILLE TRADE NODES, 18TH CENTURY
Authors: Perez-Garcia Manuel 
Published: September 2019

ABSTRACTNew global history studies have provided theoretical models related to different paths of economic growth and consumer behaviour between East Asia (mainly China and Japan) and Europe during the period of the first industrialisation. However, more research challenging the Eurocentric views of the origins of globalisation is needed. In this article, I examine the exchanges of Chinese silks and porcelains and European wines and liquors for American silver through the Swedish Grill Company. This company had extensive business activities in Canton and Macao establishing strategic links and intermediation with other relevant companies from China, Manila, Seville and Marseille. On the global level, such exchanges played a crucial role for the accumulation of American silver in China during the Qing dynasty, and the outflows of Chinese goods to the Americas and Europe fostered market integration and globalisation that occurred earlier than 1820.
Embryo culture at a reduced oxygen concentration of 5%: a mini review
Authors: Sciorio R. , Smith G.D. 
Published: September 2019

SummaryThe optimum oxygen tension for culturing mammalian embryos has been widely debated by the scientific community. While several laboratories have moved to using 5% as the value for oxygen tension, the majority of modernin vitrofertilization (IVF) laboratory programmes still use 20%. Severalin vivostudies have shown the oxygen tension measured in the oviduct of mammals fluctuates between 2% and 8% and in cows and primates this values drops to <2% in the uterine milieu. In human IVF, a non-physiological level of 20% oxygen has been used in the past. However, several studies have shown that atmospheric oxygen introduces adverse effects to embryo development, not limited to numerous molecular and cellular physiology events. In addition, low oxygen tension plays a critical role in reducing the high level of detrimental reactive oxygen species within cells, influences embryonic gene expression, helps with embryo metabolism of glucose, and enhances embryo development to the blastocyst stage. Collectively, this improves embryo implantation potential. However, clinical studies have yielded contradictory results. In almost all reports, some level of improvement has been identified in embryo development or implantation, without any observed drawbacks. This review article will examine the recent literature and discusses ongoing efforts to understand the benefits that low oxygen tension can bring to mammal embryo developmentin vitro.
Unexpected ischemia during transcatheter patent arterial duct closure
Authors: Materna Ondrej , Suchanek Vojtech , Reich Oleg 
Published: September 2019

AbstractA child undergoing routine transcatheter patent arterial duct closure developed severe transient ischemic changes in the electrocardiogram (Pardee waves) while the aortic retention skirt of the Amplatzer™ Duct Occluder was pulled against the duct orifice. The occluder was then released, and the delivery system was pulled back to inferior caval vein which led to electrocardiogram normalisation. Aortic root angiography showed a single coronary artery originating from the right sinus of Valsalva with the left coronary stem wedged behind the posterior aspect of the right ventricular outflow tract. We believe that the left coronary artery was compressed while applying tension on the occluder delivery system.
Why do parties support emigrant voting rights?
Authors: Østergaard-Nielsen Eva , Ciornei Irina , Lafleur Jean-Michel 
Published: September 2019

AbstractPolicies allowing enfranchisement of non-resident citizens (emigrants and their descendants) are now implemented in the majority of states worldwide. A growing number of case studies show that the extension of voting rights to non-resident citizens is often contested among country of origin political parties. However, there is no systematic comparative study of why different political parties support or oppose external voting rights and how this position is framed by the parties. Drawing on a unique data set based on 34 debates across 13 countries, we estimate the extent to which ideology and party family are correlated with the positioning and framing of parties. Among the findings are that the more to the right is a party, the more it tends to support external voting rights, except in the case of radical right parties. The position on emigrant voting rights is largely framed along more pragmatic arguments.
Demography and Dispossession: Explaining the Growth of the Global Informal Workforce, 1950-2000
Authors: Benanav Aaron 
Published: September 2019

AbstractSince 1950, the world’s urban labor force has expanded dramatically, a process that has been accompanied by a large increase in informal employment. Accounts of these phenomena generally assume that urban workers without formal work are mostly recent migrants from the countryside. This article shows that outside of China, most of the growth of the world’s urban workforce has been the consequence of demographic expansion rather than rural-to-urban migration. A large portion of the world’s growing urban-born workforce has ended up in informal employment. I develop a concept of demographic dispossession to explain the relatively autonomous role demographic growth has played, first, in the proletarianization of the global population and, second, in the informalization of the urban workforce. I then explore the reasons why demographic growth in low- and medium-income countries tended to be more rapid and urban than demographic growth had been historically in the high-income countries.