bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategies to improve patient-reported outcome completion rates in longitudinal studies
Authors: Nielsen Lene Kongsgaard , King Madeleine , Möller Sören , Jarden Mary , Andersen Christen Lykkegaard , Frederiksen Henrik , Gregersen Henrik , Klostergaard Anja , Steffensen Morten Saaby , Pedersen Per Trøllund , Hinge Maja , Frederiksen Mikael , Jensen Bo Amdi , Helleberg Carsten , Mylin Anne Kærsgaard , Abildgaard Niels 
Published: September 2019

Abstract

Purpose
The quality of patient-reported outcome (PRO) data can be compromised by non-response (NR) to scheduled questionnaires, particularly if reasons for NR are related to health problems, which may lead to unintended bias. The aim was to investigate whether electronic reminders and real-time monitoring improve PRO completion rate.

Methods
The population-based study “Quality of life in Danish multiple myeloma patients” is a longitudinal, multicentre study with consecutive inclusion of treatment-demanding newly diagnosed or relapsed patients with multiple myeloma. Education of study nurses in the avoidance of NR, electronic reminders, 7-day response windows and real-time monitoring of NR were integrated in the study. Patients complete PRO assessments at study entry and at 12 follow-up time points using electronic or paper questionnaires. The effect of the electronic reminders and real-time monitoring were investigated by comparison of proportions of completed questionnaires before and after each intervention.

Results
The first 271 included patients were analysed; of those, 249 (85%) chose electronic questionnaires. Eighty-four percent of the 1441 scheduled PRO assessments were completed within the 7-day response window and 11% after real-time monitoring, achieving a final PRO completion rate of 95%. A significant higher proportion of uncompleted questionnaires were completed after the patients had received the electronic reminder and after real-time monitoring.

Conclusions
Electronic reminders and real-time monitoring contributed to a very high completion rate in the study. To increase the quality of PRO data, we propose integrating these strategies in PRO studies, however highlighting that an increase in staff resources is required for implementation.
Behavior of Ga, In, Sn, and Te in Copper Matte Smelting
Authors: Sukhomlinov Dmitry , Klemettinen Lassi , O’Brien Hugh , Taskinen Pekka , Jokilaakso Ari 
Published: September 2019

Abstract
The distributions of Ga, In, Sn, and Te between copper-iron mattes and silica-saturated iron silicate slags over a wide range of matte grades 55 to 75 pct Cu were determined at 1300 °C using a gas-phase equilibration-quenching technique and direct phase composition analysis by Electron Probe X-ray Microanalysis and Laser Ablation-Inductively Coupled Plasma-Mass Spectrometry. Alumina from aluminum, a typical minor element of electric and electronic copper scrap, and lime were adopted as slag modifiers for increasing the trace element recoveries. Gallium and tin were distributed predominantly in the slag, indium preferred sulfide matte at low matte grades and slag at high, whereas tellurium strongly favored the sulfide matte in particular in high matte grades. The slag modifiers alumina and lime had a minor impact on the distribution coefficients of gallium and tin, but for indium and tellurium the distribution coefficients were more strongly affected by the basic oxides. The strong tendencies of tin and tellurium to vaporize at the experimental temperature were confirmed.
Performance comparison of novel chemical agents in improving oil recovery from tight sands through spontaneous imbibition
Authors: Huang Hai , Babadagli Tayfun , Chen Xin , Andy Li Huazhou 
Published: September 2019

Abstract
Tight sands are abundant in nanopores leading to a high capillary pressure and normally a low fluid injectivity. As such, spontaneous imbibition might be an effective mechanism for improving oil recovery from tight sands after fracturing. The chemical agents added to the injected water can alter the interfacial properties, which could help further enhance the oil recovery by spontaneous imbibition. This study explores the possibility of using novel chemicals to enhance oil recovery from tight sands via spontaneous imbibition. We experimentally examine the effects of more than ten different chemical agents on spontaneous imbibition, including a cationic surfactant (C12TAB), two anionic surfactants (O242 and O342), an ionic liquid (BMMIM BF4), a high pH solution (NaBO2), and a series of house-made deep eutectic solvents (DES3–7, 9, 11, and 14). The interfacial tensions (IFT) between oil phase and some chemical solutions are also determined. Experimental results indicate that both the ionic liquid and cationic surfactant used in this study are detrimental to spontaneous imbibition and decrease the oil recovery from tight sands, even though cationic surfactant significantly decreases the oil–water IFT while ionic liquid does not. The high pH NaBO2 solution does not demonstrate significant effect on oil recovery improvement and IFT reduction. The anionic surfactants (O242 and O342) are effective in enhancing oil recovery from tight sands through oil–water IFT reduction and emulsification effects. The DESs drive the rock surface to be more water-wet, and a specific formulation (DES9) leads to much improvement on oil recovery under counter-current imbibition condition. This preliminary study would provide some knowledge about how to optimize the selection of chemicals for improving oil recovery from tight reservoirs.
A fast and robust kernel optimization method for core–periphery detection in directed and weighted graphs
Authors: Tudisco Francesco , Higham Desmond J. 
Published: September 2019

Abstract
Many graph mining tasks can be viewed as classification problems on high dimensional data. Within this class we consider the issue of discovering core-periphery structure, which has wide applications in the economic and social sciences. In contrast to many current approaches, we allow for weighted and directed edges and we do not assume that the overall network is connected. Our approach extends recent work on a relevant relaxed nonlinear optimization problem. In the directed, weighted setting, we derive and analyze a globally convergent iterative algorithm. We also relate the algorithm to a maximum likelihood reordering problem on an appropriate core-periphery random graph model. We illustrate the effectiveness of the new algorithm on a large scale directed email network.
Feature-enriched author ranking in incomplete networks
Authors: Silva Jorge , Aparício David , Silva Fernando 
Published: September 2019

AbstractEvaluating scientists based on their scientific production is a controversial topic. Nevertheless, bibliometrics and algorithmic approaches can assist traditional peer review in numerous tasks, such as attributing research grants, deciding scientific committees, or choosing faculty promotions. Traditional bibliometrics rank individual entities (e.g., researchers, journals, faculties) without looking at the whole data (i.e., the whole network). Network algorithms, such as PageRank, have been used to measure node importance in a network, and have been applied to author ranking. However, traditional PageRank only uses network topology and ignores relevant features of scientific collaborations. Multiple extensions of PageRank have been proposed, more suited for author ranking. These methods enrich the network with information about the author’s productivity or the venue and year of the publication/citation. Most state-of-the-art (STOA) feature-enriched methods either ignore or do not combine effectively this information. Furthermore, STOA algorithms typically disregard that the full network is not known for most real-world cases.Here we describe OTARIOS, an author ranking method recently developed by us, which combines multiple publication/citation criteria (i.e., features) to evaluate authors. OTARIOS divides the original network into two subnetworks,insidersandoutsiders, which is an adequate representation of citation networks with missing information. We evaluate OTARIOS on a set of five real networks, each with publications in distinct areas of Computer Science, and compare it against STOA methods. When matching OTARIOS’ produced ranking with a ground-truth ranking (comprised of best paper award nominations), we observe that OTARIOS is >30%more accurate than traditional PageRank (i.e., topology based method) and >20%more accurate than STOA (i.e., competing feature enriched methods). We obtain the best results when OTARIOS considers (i) the author’s publication volume and publication recency, (ii) how recently the author’s work is being cited by outsiders, and (iii) how recently the author’s work is being cited by insiders and how individual he is. Our results showcase (a) the importance of efficiently combining relevant features and (b) how to adequately perform author ranking in incomplete networks.
Kelvin–Helmholtz billows above Richardson number
Authors: Parker J. P. , Caulfield C. P. , Kerswell R. R. 
Published: September 2019

We study the dynamical system of a two-dimensional, forced, stratified mixing layer at finite Reynolds number $Re$, and Prandtl number $Pr=1$. We consider a hyperbolic tangent background velocity profile in the two cases of hyperbolic tangent and uniform background buoyancy stratifications, in a domain of fixed, finite width and height. The system is forced in such a way that these background profiles are a steady solution of the governing equations. As is well known, if the minimum gradient Richardson number of the flow, $Ri_{m}$, is less than a certain critical value $Ri_{c}$, the flow is linearly unstable to Kelvin–Helmholtz instability in both cases. Using Newton–Krylov iteration, we find steady, two-dimensional, finite-amplitude elliptical vortex structures – i.e. ‘Kelvin–Helmholtz billows’ – existing above $Ri_{c}$. Bifurcation diagrams are produced using branch continuation, and we explore how these diagrams change with varying $Re$. In particular, when $Re$ is sufficiently high we find that finite-amplitude Kelvin–Helmholtz billows exist when $Ri_{m}>1/4$ for the background flow, which is linearly stable by the Miles–Howard theorem. For the uniform background stratification, we give a simple explanation of the dynamical system, showing the dynamics can be understood on a two-dimensional manifold embedded in state space, and demonstrate the cases in which the system is bistable. In the case of a hyperbolic tangent stratification, we also describe a new, slow-growing, linear instability of the background profiles at finite $Re$, which complicates the dynamics.
Isogeometric Analysis of the Dual Boundary Element Method for the Laplace Problem With a Degenerate Boundary
Authors: Kao J. H. , Chen K. H. , Chen J. T. , Kuo S. R. 
Published: September 2019

ABSTRACTIn this paper, we develop the isogeometric analysis of the dual boundary element method (IGA-DBEM) to solve the potential problem with a degenerate boundary. The non-uniform rational B-Spline (NURBS) based functions are employed to interpolate the geometry and physical function. To deal with the rank-deficiency problem due to the degenerate boundary, the hypersingular integral equation is introduced to promote the full rank for the influence matrix in the dual BEM. Finally, three numerical examples are given to verify the accuracy of our proposed method. Both circular and square domains subjected to the Dirichlet boundary condition are considered. The engineering problem containing a degenerate boundary is considered, e.g., a seepage flow problem with a sheet pile. Numerical results of the IGA-DBEM agree well with these of the exact solution and the original dual boundary element method.
Aragonite bias exhibits systematic spatial variation in the Late Cretaceous Western Interior Seaway, North America
Authors: Dean Christopher D. , Allison Peter A. , Hampson Gary J. , Hill Jon 
Published: September 2019

AbstractPreferential dissolution of the biogenic carbonate polymorph aragonite promotes preservational bias in shelly marine faunas. While field studies have documented the impact of preferential aragonite dissolution on fossil molluscan diversity, its impact on regional and global biodiversity metrics is debated. Epicontinental seas are especially prone to conditions that both promote and inhibit preferential dissolution, which may result in spatially extensive zones with variable preservation. Here we present a multifaceted evaluation of aragonite dissolution within the Late Cretaceous Western Interior Seaway of North America. Occurrence data of mollusks from two time intervals (Cenomanian/Turonian boundary, early Campanian) are plotted on new high-resolution paleogeographies to assess aragonite preservation within the seaway. Fossil occurrences, diversity estimates, and sampling probabilities for calcitic and aragonitic fauna were compared in zones defined by depth and distance from the seaway margins. Apparent range sizes, which could be influenced by differential preservation potential of aragonite between separate localities, were also compared. Our results are consistent with exacerbated aragonite dissolution within specific depth zones for both time slices, with aragonitic bivalves additionally showing a statistically significant decrease in range size compared with calcitic fauna within carbonate-dominated Cenomanian–Turonian strata. However, we are unable to conclusively show that aragonite dissolution impacted diversity estimates. Therefore, while aragonite dissolution is likely to have affected the preservation of fauna in specific localities, time averaging and instantaneous preservation events preserve regional biodiversity. Our results suggest that the spatial expression of taphonomic biases should be an important consideration for paleontologists working on paleobiogeographic problems.
Do documented records and retrospective reports of childhood maltreatment similarly predict chronic inflammation?
Authors: Osborn Max , Widom Cathy Spatz 
Published: September 2019

AbstractBackgroundChildhood adversities have been associated with chronic inflammation and risk for cardiovascular disease. With some exceptions, existing knowledge of this relationship is based on retrospective self-reports, potentially subject to recall bias or memory problems. We seek to determine whether childhood maltreatment is associated with higher C-reactive protein (CRP) later in life and whether individuals with official and retrospective self-reports of maltreatment and men and women show similar increases in risk.MethodsData are from in-person interviews in 2009–2010 with 443 offspring (mean age = 23.4) of parents in a longitudinal study of the consequences of childhood maltreatment. Official reports of maltreatment were abstracted from 2011–2013 Child Protective Services records. Eleven measures were used to assess self-reported maltreatment retrospectively. Seventeen percent of offspring had official reports, whereas self-reported prevalence rates ranged from 5.4% to 64.8%. CRP was assessed through blood spot samples. Regression models were used to estimate the effect of maltreatment on inflammation, adjusting for age, sex, race, parent occupational status, current depression, smoking, and heavy drinking.ResultsIndividuals with official reports of child maltreatment and, specifically, physical abuse, had significantly higher levels of CRP than non-maltreated individuals. Maltreated females showed elevated CRP, independent of control variables, whereas no significant association was observed in males. Retrospective self-report measures of child maltreatment did not predict elevated CRP.ConclusionsIndividuals with documented histories of childhood maltreatment are at increased risk for chronic inflammation and may benefit from targeted interventions. The results strengthen inferences about the effects of childhood maltreatment on inflammation in females.
Object transfers: An embodied resource to progress joint activities and build relative agency
Authors: Tuncer Sylvaine , Haddington Pentti 
Published: September 2019

ABSTRACTThis article builds on ethnomethodological, conversation analytic research on object transfers: how participants hand over objects to one another. By analyzing video recordings of mundane (cars) and institutional interactions (laboratories), we focus on situations where an object is central to and talked about in the joint course of action. We focus on different organizations of object transfer and show that one embodied move is decisive, either a sequentially implicative ‘give’ or an arm extension designed as a stand-alone ‘take’. We examine the interrelationship between the organization of the object transfer and the broader course of action (e.g. request or offer sequence), which is either overlapping or intersecting. We demonstrate that by making the decisive move, either the participant initially holding the object or her recipient critically influences the progression and trajectory of the activity, and displays agency. (Ethnomethodology, Conversation Analysis, multimodal interactions, objects in interaction, object transfers, agency)*
Reference genes selection for real-time quantitative PCR analysis in mouse germinal vesicle oocytes
Authors: Filatov M.A. , Nikishin D.A. , Khramova Y.V. , Semenova M.L. 
Published: September 2019

SummaryReference gene selection in mouse oocytes is an important task required to perform further adequate analysis of target gene expression levels. In the current work we have analyzed expression stability of the seven most commonly used reference genes (Actb, Eef1e1, Gapdh, H2afz, Ppia, Rpl4andUbc) in mouse oocytes at the germinal vesicle (GV) stage. We have performed analysis of expression stability of the above-mentioned reference genes with the three most commonly used software tools: geNorm, BestKeeper and NormFinder. Taking into account the results obtained from all of these programmesGapdh, Rpl4andH2afzseem to be suitable candidate reference genes in GV oocytes of mouse.
Time-Based Prospective Memory Is Associated with Functional Performance in Persons with MS
Authors: Weber Erica , Chiaravalloti Nancy D. , DeLuca John , Goverover Yael 
Published: September 2019

AbstractObjective:Persons with multiple sclerosis (MS) often report prospective memory (PM) failures that directly impact their everyday life. However, it is not known whether PM deficits confer an increased risk of poorer everyday functioning. The aims of this study were to: (1) compare time- (Time-PM) and event-based PM (Event-PM) performance between persons with MS and healthy controls (HCs), (2) examine the neuropsychological correlates of PM in MS, and (3) examine the relationship between PM and everyday functioning in MS.Method:A between-subjects design was used to examine 30 adults with MS and 30 community-dwelling HC. Participants were administered the Memory for Intentions Screening Test (MIST) to assess PM skills, the Actual Reality™ (AR) to assess everyday functioning, and a battery of cognitive tests.Results:The MS group performed significantly worse on Time-PM compared to HC but not on Event-PM tasks. While both Time-PM and Event-PM subscales were correlated with retrospective learning and memory, the MIST Time-PM subscale was correlated with executive functions. Significant correlations were observed between AR and the MIST Time-PM, but not Event-PM, subscales.Conclusions:The results highlight the role of executive functions on Time-PM. Furthermore, significant relationships with AR extend the ecological validity of the MIST to MS populations.
What do we call money? An appraisal of the money or non-money view
Authors: Frasser Cristian , Guzmán Gabriel 
Published: September 2019

AbstractPart of the debate fueled by cryptocurrencies has revolved around the question of what we call money. This paper identifies two traditions in monetary theory that have tried to answer that question. On the one hand,the money or non-money viewfollows a strategy proposed by a version ofphilosophical essentialism, in which there is a set of defining characteristics of money that make it categorically different from other things used in transactions. On the other hand,the liquidity degree viewemphasizes that the multiple objects that circulate as a means of payment differ in their degree of acceptability. Since there is no absolute standard of liquidity, a precise dividing line between money and non-money cannot be drawn. We challengethe money or non-money view, arguing that there is nothing in the nature of money that can be interpreted as a natural kind essence by which money can be categorically separated from non-money.
The loss of ERE-dependent ERα signaling potentiates the effects of maternal high-fat diet on energy homeostasis in female offspring fed an obesogenic diet
Authors: Roepke Troy A. , Yasrebi Ali , Villalobos Alejandra , Krumm Elizabeth A. , Yang Jennifer A. , Mamounis Kyle J. 
Published: September 2019

AbstractMaternal high-fat diet (HFD) alters hypothalamic programming and disrupts offspring energy homeostasis in rodents. We previously reported that the loss of ERα signaling partially blocks the effects of maternal HFD in female offspring fed a standard chow diet. In a companion study, we determined if the effects of maternal HFD were magnified by an adult obesogenic diet in our transgenic mouse models. Heterozygous ERα knockout (wild-type (WT)/KO) dams were fed a control breeder chow diet (25% fat) or a semipurified HFD (45% fat) 4 weeks prior to mating with heterozygous males (WT/KO or WT/ knockin) to produce WT, ERα KO, or ERα knockin/knockout (KIKO) (no estrogen response element (ERE) binding) female offspring, which were fed HFD for 20 weeks. Maternal HFD potentiated the effects of adult HFD on KIKO and KO body weight due to increased adiposity and decreased activity. Maternal HFD also produced KIKO females that exhibit KO-like insulin intolerance and impaired glucose homeostasis. Maternal HFD increased plasma interleukin 6 and monocyte chemoattractant protein 1 levels andG6pcandPepckliver expression only in WT mice. Insulin and tumor necrosis factor α levels were higher in KO offspring from HFD-fed dams. Arcuate and liver expression ofEsr1was altered in KIKO and WT, respectively. These data suggest that loss of ERE-dependent ERα signaling, and not total ERα signaling, sensitizes females to the deleterious influence of maternal HFD on offspring energy and glucose potentially through the control of peripheral inflammation and hypothalamic and liver gene expression. Future studies will interrogate the tissue-specific mechanisms of maternal HFD programming through ERα signaling.
IGEMS: The Consortium on Interplay of Genes and Environment Across Multiple Studies — An Update
Authors: Pedersen Nancy L. , Gatz Margaret , Finch Brian K. , Finkel Deborah , Butler David A. , Dahl Aslan Anna , Franz Carol E. , Kaprio Jaakko , Lapham Susan , McGue Matt , Mosing Miriam A. , Neiderhiser Jenae , Nygaard Marianne , Panizzon Matthew , Prescott Carol A. , Reynolds Chandra A. , Sachdev Perminder , Whitfield Keith E. 
Published: September 2019

AbstractThe Interplay of Genes and Environment across Multiple Studies (IGEMS) is a consortium of 18 twin studies from 5 different countries (Sweden, Denmark, Finland, United States, and Australia) established to explore the nature of gene–environment (GE) interplay in functioning across the adult lifespan. Fifteen of the studies are longitudinal, with follow-up as long as 59 years after baseline. The combined data from over 76,000 participants aged 14–103 at intake (including over 10,000 monozygotic and over 17,000 dizygotic twin pairs) support two primary research emphases: (1) investigation of models of GE interplay of early life adversity, and social factors at micro and macro environmental levels and with diverse outcomes, including mortality, physical functioning and psychological functioning; and (2) improved understanding of risk and protective factors for dementia by incorporating unmeasured and measured genetic factors with a wide range of exposures measured in young adulthood, midlife and later life.