bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of C-Means Clustering Based Adaptive Fuzzy Controller for a Flapping Wing Micro Air Vehicle
Authors: Ferdaus Md Meftahul , Anavatti Sreenatha G. , Garratt Matthew A. , Pratama Mahardhika 
Published: January 2019

Abstract
Advanced and accurate modelling of a Flapping Wing Micro Air Vehicle (FW MAV) and its control is one of the recent research topics related to the field of autonomous MAVs. Some desiring features of the FW MAV are quick flight, vertical take-off and landing, hovering, and fast turn, and enhanced manoeuvrability contrasted with similar-sized fixed and rotary wing MAVs. Inspired by the FW MAV’s advanced features, a four-wing Nature-inspired (NI) FW MAV is modelled and controlled in this work. The Fuzzy C-Means (FCM) clustering algorithm is utilized to construct the data-driven NIFW MAV model. Being model free, it does not depend on the system dynamics and can incorporate various uncertainties like sensor error, wind gust etc. Furthermore, a Takagi-Sugeno (T-S) fuzzy structure based adaptive fuzzy controller is proposed. The proposed adaptive controller can tune its antecedent and consequent parameters using FCM clustering technique. This controller is employed to control the altitude of the NIFW MAV, and compared with a standalone Proportional Integral Derivative (PID) controller, and a Sliding Mode Control (SMC) theory based advanced controller. Parameter adaptation of the proposed controller helps to outperform it static PID counterpart. Performance of our controller is also comparable with its advanced and complex counterpart namely SMC-Fuzzy controller.
A Framework for Multidisciplinary Business Simulations
Authors: Busbach-Richard Uwe , Dietrich Antje 
Published: January 2019

Abstract
In this paper, the design and introduction of a framework for multidisciplinary business simulations at the School of Public Administration of Kehl University will be presented. Within Kehl’s Public Administration study program, various subjects like organization, law, human resources, computer sciences, finance, psychology and economics are supported in an interdisciplinary way. Both theoretical and scientific skills as well as soft skills such as teamwork, project management and coordination will be further developed by using an interdisciplinary approach. A framework for multidisciplinary business simulations has been developed to support this interdisciplinary approach. The framework integrates realistic and practical simulations of interdisciplinary case studies into the study program of Public administration at Kehl University. In order to reduce costs for case study development, the framework offers a generic case study pattern. This pattern was purposefully developed and covers very different disciplines in the best possible way so that the students can conduct simulations that are realistic and possible during their studies. Further, two different simulation implementations of the case studies were designed within the framework for multidisciplinary business simulations. A short-term simulation intends to check the ongoing learning success. A long-term simulation aims for giving students feedback concerning their skills just before graduating. The case studies based on the generic case study pattern come from a wide variety of public administration tasks. Examples of currently conceived case studies include e-invoicing, IT-infrastructure for schools and IT-office workplaces. The case studies were developed together with practitioners from municipalities and local agencies in order to create realistic simulations. This addresses the actual complexity of the future working environment of students. The comprehensive application of knowledge learnt in different subjects motivates students to work on these case studies.
Relationships between grain size in self-developed soft magnetic composites and the Grucad hysteresis model
Authors: Jastrzȩbski Radosław , Jakubas Adam , Chwastek Krzysztof 
Published: January 2019

Abstract
Soft magnetic composites (SMCs) have been in the spotlight of magnetic community due to their unique properties which can easily be tailored up to a specific application. The present paper is focused on the possibility to develop SMC cores produced from iron powder mixed with suspense polyvinyl chloride. Important processing parameters like grain size are correlated with the parameters of a simple phenomenological hysteresis model developed by the Grucad research group.
Research of magnetic properties of spolic technosols (alcalic/hyperartefactic) on the landfill of industrial waste from nickel production
Authors: Reiffers Marián , Vilček Jozef , Michaeli Eva , Čurlík Ivan , Klamár Radoslav , Čech Vladimír , Ivanová Monika , Koco Štefan , Pasternák Tomáš , Il’kovič Sergej , Parma Ludvík , Šebeň Vladimír , Šterbáková Katarína , Litecká Juliána , Csatáryová Mária , Zapotoková Mariana , Solar Vladimír 
Published: January 2019

Abstract
The article presents the results of measurements of magnetic properties of samples spolic technosols (alcalic/hyperartefactic) form the landfill of black nickel mud at Sered’, Slovakia. We measured the dependence of magnetic moment as a function of temperatures (240-340 K) and applied magnetic fields up to 7.2 MA/m (90 kOe). We observed at room temperature the tendency to saturation of magnetic moment. The temperature dependences showed possible ferromagnetic behaviour.
Fatty acid profile in fat obtained from edible part of land snails harvested in Poland
Authors: Szkucik Krzysztof , Ziomek Monika , Paszkiewicz Waldemar , Drozd Łukasz , Gondek Michał , Knysz Przemysław 
Published: January 2019

Abstract

Introduction: The objective was to determine the content of fatty acids in edible snail fat by snail species, collection site, and processing stage.

Material and Methods: The research material comprised 180 edible fat samples from the three genera of edible snails collected in Poland: free-living Helix pomatia (HP) and two cultivated Cornu subspecies: C. aspersa maxima (CAM) and C. aspersum aspersum (CAA). All snails came from the Greater Poland and Lower Silesian Provinces: HP from their natural habitat and CAM and CAA from heliciculture farms. The studies focused on the raw meat, cooked meat, and frozen meat processing stages. Fatty acid (FA) profiles were determined by the gas chromatography method.

Results:
Helix pomatia fat showed a higher saturated fatty acid (SFA) content, whereas the fat of Cornu genus snails had a higher unsaturated fatty acid (UFA) component, i.e. monounsaturated fatty acid (MUFA) and polyunsaturated fatty acid (PUFA). Thermal processing of snail meat increased all the determined SFA and decreased all the PUFA values, and increased the content of C18:1, C20:1, and C22:1 acids in the MUFA group. The material collection site had limited impact on FA content as differences were noted only in levels of C18:1, C18:2 n6, and C20:5. The differences pertained only to the fat of farmed snails of the Cornu genus.

Conclusion: Due to the high content of UFA and a favourable ratio of n6:n3 acids and PUFA:SFA, snail fat can be regarded as nutritionally valuable.
Alkali-silica Reaction in Finnish Concrete Structures
Authors: Lahdensivu Jukka , Kekäläinen Pirkko , Lahdensivu Alina 
Published: January 2019

Abstract
Even though natural phenomena do not abide to borders, Finland has traditionally been considered an alkali-silica reaction (ASR) free country. This is due to exceptional quality of the mostly course crystalline igneous rocks. However, during the last few years dozens of cases of ASR have been reported. The scope of this study was to study the occurrence of ASR, and to find out the initiation time of the reaction in resent investigations of Finnish concrete structures. ASR is found occurring all over Finland. The reacting aggregates consist of rock types, which are considered relatively stable or low reacting in literature.
Rice Husk Resource for Energy and Cementitious Products with Low CO2 Contributions
Authors: During Otto , Bhochhibhoya Silu , Maskey Ramesh Kumar , Joshi Rajendra 
Published: January 2019

Abstract
Rice Husk Ash (RHA) is a well-known supplementary cementitious materials (SCMs) that can be used for concrete with reduced CO2 contributions. In 2016, only Nepal produced 5.2 million tonnes rice that gave about 1.14 million tonnes rice husk. The rice husk can also be used directly in a cement kiln as a fuel. This study analysis the potential CO2 reductions from three scenarios and emphasis strengths, weaknesses, opportunities and treats in the production systems for initiate a decision process with possibilities to get an industry project financed from the green climate found. The highest CO2 benefits were from rice husk used in a cement kiln were half of the yearly rice husk production in Nepal could reduce the climate impact with 808000 tonnes CO2.
Nutritional Assessment of Dialysis Patient with a Web-Based Tool Allows More Accurate Treatment of Malnutrition
Authors: Ferlinc Mihela , Knap Bojan 
Published: January 2019

Abstract

Background/Aims: Regular assessment of nutritional status of dialysis patients is vital for preventing malnutrition and protein energy wasting. The aim of this clinical study was to analyze dietary intake of dialysis patients and to determine if it meets their nutritional needs.

Methods: Clinical study was conducted on 30 randomly selected dialysis patients in the dialysis department of the University Medical Centre Ljubljana. Nutritional interview was conducted unannounced five times over a period of three months with the 24-hour recall method. Results were analyzed with Prodi 6.6 Expert software. Body composition was measured with bioimpedance spectroscopy.

Results: Average caloric intake of 30 patients is 14.1 ± 4.7 kcal/kg body weight per day, average protein intake is 0.61 ± 0.19 g/kg body weight per day. The average BMI (body mass index) is 27.9 ± 4.4 kg/m2, the average LTI (lean tissue index) is 12.5 ± 3.1 kg/m2, the average FTI (fat tissue index) is 14.2 ± 5.7 kg/m2 and the average phase angle is 4.2 ± 1.0. Average calorie intake and protein intake are inadequate according to the dietary recommendations for dialysis patients. Anthropometric measurements indicate sarcopenic obesity.

Conclusion: According to the aim of the study, we confirmed that caloric and protein intake of dialysis patients were inadequate according to their needs. Depending on the results of nutritional analysis and bioimpedance measurements, we have confirmed the presence of protein energy wasting among observed patients.
Hyperfibrinogenemia in Peripheral Arterial Disease: Coexistent and Independent Risk Factor (A Report of Two Cases and Review of Literature)
Authors: Bosevski Marijan , Krstevski Gorjan , Mitevska Irena , Antova Emilija , Bosevska Golubinka 
Published: January 2019

Abstract
These case reports aim to show that hyperfibrinogenemia is a risk factor for the progression and prognosis of peripheral arterial disease (PAD), in patients with and without diabetes mellitus type 2.
We present a patient with PAD who has type 2 diabetes mellitus, who has previously been repeatedly treated for lower limb ischemia with multiple vascular surgeries performed. A few weeks before admission the patient developed critical lower limb ischemia, which was treated with an iliaco-popliteal and femorofemoral bypass. The patient had elevated serum fibrinogen values. In the current admission, renewed left limb ischemia was diagnosed, and surgically evaluated with a recommendation for amputation of the left limb as a surgical recommendation. Our second patient had a stable intermittent claudication, dyslipidemia and hyperfibrinogenemia. He was successfully treated for those risk factors. Regular monitoring of the patient showed improved claudication distance and quality of life
Our case reports, supported by a literature review, demonstrate that hyperfibrinogenemia is a possible risk factor for progression and the prognosis of PAD.
Evaluation of Correlation Between the Pharmacogenetic Profiles of Risperidone Treated Psychiatry Patients with Plasma and Urine Concentration of Risperidone and its Active Moiety 9-OH Risperidone Determined with Optimized Bioanalytical LC Method
Authors: Filipce Ana , Naumovska Zorica , Nestorovska Aleksandra Kapedanovska , Sterjev Zoran , Brezovska Katerina , Tonic-Ribarska Jasmina , Grozdanova Aleksandra , Suturkova Ljubica , Raleva Marija 
Published: January 2019

Abstract
Atypical antipsychotic risperidone is widely used first-line monotherapy in schizophrenia and combined therapy in bipolar disorders. Therapeutic plasma concentrations of risperidone and its active moiety are directly influenced by genetic variations in metabolic CYP450 enzymes (CYP2D6 and CYP3A4/5) and transporter (ABCB1) protein and additional environmental factors. Since active metabolite 9-OH risperidone has a greater percentage of the pharmacologically active fraction and is equipotent to the parent drug risperidone, it is assumed that it contributes significantly to therapeutic and adverse effects.
Unpredictable dose/concentration ratio, narrow therapeutic index, number of interactions, along with serious adverse reactions (ADR), raises the need for individualization of risperidone treatment and establishing of good therapeutic regime using TDM.
A simple and reliable validated bioanalytical liquide-liquide extraction HPLC/UV method was applied for the simultaneous determination of risperidone and its active metabolite, 9-OH risperidone, in human plasma and urine of 52 hospitalized schizophrenia/bipolar disorder patients treated with risperidone as monotherapy and in polytherapy. All the patients were previously genotyped for CYP2D6 (EM=30, EM/IM=14, IM=4 IM/PM=1 and PM=3) and ABCB1 using Real-Time PCR methods with TaqMan SNP genotyping suitable assays according to the guidelines of the manufacturer (Life Technologies, USA).The influence of CYP2D6 phenotype on metabolic ratio MR (Ris/9-OHRis) in plasma (p=0.012) and in urine (p=0.048) was confirmed. Statistically significant correlation (R2=55.53%, Rho=0.844, p<0,0001) for MR in both plasma and urine indicates that urine may be utilized as appropriate media for initial CYP2D6 phenotype identification and selection of patients on risperidone treatment with high risk for ADR.
Evaluation of Pain Following the Use of Scalpel Versus Electrosurgery for Skin Incisions in the Facial Regions
Authors: Peneva Margarita , Gjorgjeska Andrijana , Gjorgova Smilja Tudzarova , Dzonov Boro , Noveski Lazo , Ginoski Vladimir , Tolevska Roza Dzoleva , Breshkovska Hristina 
Published: January 2019

Abstract

Introduction: Postoperative pain presents a significant medical problem. It can create a considerable discomfort in the immediate postoperative period and thus increase patient’s morbidity. Multiple mechanisms are involved in its’ etiology, one of them being the method of tissue incision. The aim of this study is to compare the early postoperative pain following incision with two different methods, scalpel and electrosurgery in the facial regions.

Material and methods: Eighty patients with both benign and malignant skin lesions in the facial regions undergoing surgery were enrolled in this study. Patients were randomized in two groups. In group A, comprising 40 patients, cold steel surgical scalpel №15 was used for the surgical procedure. Electrosurgical microneedle with 0.06mm tip radius and generator unit KLS Martin Electrosurgical Unit ME MB 2 set on cutting mode, power 12 W was used for performing the surgery in group B including the same number of patients. After the surgery patients were given analgesics on their demand. The total number of on demand analgesics requirements was calculated. The patients were also asked to note the oral analgesics they were taking after being released from the hospital.

Results: Results of this study showed a statistically significant difference between the groups in the analgesics demand on the day of the operation (p=0.041). On the day of the operation 52.5% patients in the scalpel group and only 30% of the patents of the electrosurgery group received analgesics on demand. In all other analysed time points, the patients in the scalpel group received analgesics more often than the patients in the microneedle group, but with no statistically confirmed difference between the groups (p>0.05). Even more significant is the fact that patients treated with electrosurgery that needed analgesics, had significantly bigger excision area median 471 (rank 283-589) compared to the patients treated with the conventional method 289 (rank 177-432) (p=0.016).

Conclusion: In accordance with previous studies our results suggested a significantly reduced postoperative pain in the electrosurgery group.
A 4-Year-Old Boy with Beckwith Wiedemann Syndrome (BWS)
Authors: Janchevska Aleksandra , Tasic Velibor , Laban Nevenka , Polenakovic Momir , Gucev Zoran , Bachmann Nadine , Bergmann Carsten 
Published: January 2019

Abstract

Objectives: Molecular characterization of a patient with BWS.

Clinical presentation and intervention: A 4-year-old boy with overgrowth (weight above 99th and height at 99th percentile) had longitudinal hemihypertrophy of the tongue and left cheek. In addition, there was a difference of one centimeter in the circumference of the left and right leg. Molecular genetic analysis revealed hypomethylation of KvDRM1 (LIT1) in the imprinting control region-2 (ICR2) on chromosome 11p15.5 and a normal methylation pattern of the H19-differentially methylated region (H19-DMR) in the ICR1. The estimated tumor risk was 1-5%.

Conclusion: This patient with clinical characteristics of BWS has an imprinting defect associated with a low risk of embryonal tumors.
Does the Nature of Interactions with Higher Education Institutions Influence the Innovative Capabilities of Creative Firms? The Case of a South-Western Norwegian County
Authors: Calignano Giuseppe , Jøsendal Kari 
Published: January 2019

AbstractOur study contributes to a limited body of literature and aims to examine the type and frequency of linkages between creative industries and higher education institutions (HEIs). The objective of our study is to investigate the extent to which various types of linkages contribute to enhanced innovative capabilities in creative industries. Based on a qualitative research design and a case study carried out in a peripheral south-western Norwegian county, our empirical analysis shows that HEIs are generally not very relevant partners and that other actors are mainly involved in innovation dynamics. As clarified and discussed in the paper, this finding largely depends on some specific characteristics of HEIs, the form of knowledge primarily employed by creative firms (symbolic knowledge base), and the cultural divergence between the two spheres.
Monitoring of Bioactive Compounds of Tomato Cultivars as Affected by Mulching Film
Authors: Valšíková M. , Mlček J. , Snopek L. , Rehuš M. , Škrovánková S. , Juríková T. , Sumczynski D. , Paulen O. 
Published: January 2019

Abstract
The influence of varieties and the effect of mulching film on antioxidant capacity, polyphenol content, ascorbic acid content, and yield of tomato fruits were investigated. Results of two years (2012 and 2013) investigations were compared. The results proved a statistically significant effect of year, mulching film, and variety on the content of total polyphenols (0.92–1.49 g gallic acid equivalents per kg of fresh weight (FW), ascorbic acid (26.66–38.62 mg per 100 g FW), and antioxidant capacity (1.12–1.94 g ascorbic acid equivalents per kg FW), while the values were the highest in 2013 and in uncovered soil. Conversely, a higher yield was found in mulching film compared with uncovered soil, also in 2013 (48.65–120.38 t ha−1). There was a negative correlation between the yield and the content of bioactive compounds (BC) and antioxidant capacity. The content of bioactive substances, antioxidant capacity, and yield of tomato fruits is dependent on the vintage, agronomical interventions, and genotype.
Localization of Estrogen Receptors in Male Reproductive Tissues and Sperm Cells – A Review
Authors: Krejčířová R. , Postlerová P. , Rajmon R. 
Published: January 2019

AbstractThe effect of endogenous estrogens on the male reproductive tissues and development of gametes is an essential for the reproductive success. Estrogens affect the target cells via estrogen receptors (ERs) by both genomic and non-genomic pathways. The ER localization in the testis, epididymis, and sperm cells is a key to understanding the effect of estrogens on the sperm development, maturation, and function. The ER detection in male reproductive tissues and sperm cells at different development stages is described in representative mammalian species (human, mouse, rat, horse, and pig), in which the ER localization has been most described. According to various authors the ER occurrence in the male reproductive tissues and spermatozoa is quite distinct. Discrepancy in the published results is probably caused either by the application of different tissue preparation methods, or the choice of specific antibodies. Inconsistent findings should be subjected to further investigation to better understand the role of ERs in the male gamete development and mammalian reproduction
Analysis of Cutaneous Microbiota of Piglets with Hereditary Melanoma
Authors: Švejstil R. , Salmonová H. , Čížková J. 
Published: January 2019

Abstract
Malignant melanoma may be a life-threatening disease caused by various conditions. Cutaneous bacteria could play a role in melanoma development or regression. The present work aimed to analyze the bacterial species present on the epidermis of piglets with hereditary melanoma. Bacteria isolated by swabs directly from melanomas and healthy epidermis were analysed using MALDI-TOF mass spectrometry. From the total of 290 isolates, 92 were identified, while the extraction by ethanol turned out to be more efficient compared to identification by direct transfer. Staphylococcus sciuri, Staphylococcus cohnii, and Lactococcus lactis were significantly more frequent on healthy skin, whereas Staphylococcus chromogenes, Staphylococcus hyicus, and Enterococcus faecalis have thrived significantly better on melanoma. Overall, the results indicate that the micro-biota of melanoma is different from that of healthy epidermis, so piglet skin bacteria inspections are recommended.
Adhesive Property of Different Strains of Lactobacilli in The Presence of Resveratrol
Authors: Jarosova V. , Doskocil I. , Volstatova T. , Havlik J. 
Published: January 2019

Abstract
The ability of bacteria to adhere to the intestinal epithelial cells is one of the main criteria for selection of new probiotic strains. Some dietary polyphenols have been proven to affect bacterial adhesion, providing a rationale for the use of mixtures of polyphenols and probiotics. Resveratrol, a naturally occurring stilbene in plants, has been shown to have a number of beneficial biological effects. The adhesion ability of four Lactobacillus strains (Lactobacillus brevis, L. fermentum, L. gasseri, and L. plantarum), in the presence of resveratrol, has been investigated in an in vitro model based on mixed co-culture of Caco-2 and HT29-MTX intestinal epithelial cells. The effective concentration of resveratrol used in the adhesion experiment has been selected based on cytotoxicity test. Resveratrol at three physiologically low concentrations (4.5, 2.25, and 1.125 µg ml−1), added together with the bacterial suspension, had no statistically significant influence on the adhesion of any strain (P < 0.05). Since the health benefits of polyphenols are often associated with the composition of gut microbiota, the knowledge of interactions between known bacteria and polyphenols would be of high scientific value.