bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatial epidemiological approaches to inform leptospirosis surveillance and control: A systematic review and critical appraisal of methods
Authors: Dhewantara Pandji W. , Lau Colleen L. , Allan Kathryn J. , Hu Wenbiao , Zhang Wenyi , Mamun Abdullah A. , Soares Magalhães Ricardo J. 
Published: December 2018

AbstractLeptospirosis is a global zoonotic disease that the transmission is driven by complex geographical and temporal variation in demographics, animal hosts and socioecological factors. This results in complex challenges for the identification of high‐risk areas. Spatial and temporal epidemiological tools could be used to support leptospirosis control programs, but the adequacy of its application has not been evaluated. We searched literature in six databases including PubMed, Web of Science, EMBASE, Scopus, SciELO and Zoological Record to systematically review and critically assess the use of spatial and temporal analytical tools for leptospirosis and to provide general framework for its application in future studies. We reviewed 115 articles published between 1930 and October 2018 from 41 different countries. Of these, 65 (56.52%) articles were on human leptospirosis, 39 (33.91%) on animal leptospirosis and 11 (9.5%) used data from both human and animal leptospirosis. Spatial analytical (n = 106) tools were used to describe the distribution of incidence/prevalence at various geographical scales (96.5%) and to explored spatial patterns to detect clustering and hot spots (33%). A total of 51 studies modelled the relationships of various variables on the risk of human (n = 31), animal (n = 17) and both human and animal infection (n = 3). Among those modelling studies, few studies had generated spatially structured models and predictive maps of human (n = 2/31) and animal leptospirosis (n = 1/17). In addition, nine studies applied time‐series analytical tools to predict leptospirosis incidence. Spatial and temporal analytical tools have been greatly utilized to improve our understanding on leptospirosis epidemiology. Yet the quality of the epidemiological data, the selection of covariates and spatial analytical techniques should be carefully considered in future studies to improve usefulness of evidence as tools to support leptospirosis control. A general framework for the application of spatial analytical tools for leptospirosis was proposed.
Latihan Staf Dalam Pelaksanaan Mata Pelajaran Teknologi Kejuruteraan, Lukisan Kejuruteraan dan Reka Cipta Di Sekolah Menengah Harian
Authors: Mohd Taib Mohd Tafizam , Mustapha Ramlee 
Published: December 2018

Since 1996, the technical subjects comprised of Engineering Technology (TK), Engineering Drawing (LK) and Inventions (RC) have been introduced as elective subjects for Form 4 and Form 5 students. Examination results for TK, LK and RC from 2006 to 2010 in the Sijil Pelajaran Malaysia (SPM) Examination were less encouraging and shows some declination of students performance. Data from the Ministry of Education also show a decline in students’ enrolment in TK, LK and RC between 10 to 17 percent from 2009 to 2011. Hence, this study was conducted to evaluate on the implementation of TK, LK and RC in the input, process and product dimensions. A CIPP model was used as a conceptual framework for the study. Research design used in this study was programme evaluation. Stratified random sampling was used to select 712 respondents from national secondary schools in Peninsular Malaysia consisted of 159 administrators, 176 teachers and 377 students. Questionnaires, interview protocols and observation checklists were used as instruments in this study. Cronbach Alpha reliability index for the three sets of questionnaires were between 0.77 to 0.95. Descriptive and inferential statistics were used to analyse the data. The empirical data of the study found that staff training aspects need to be improved, especially staff training organized by the Ministry of Education and the Department of Education in terms of knowledge and skills of teachers for all three subjects.Interview and observation data were also presented to support the quantitative findings. Implications and recommendations for teaching and learning as well as for future research are presented and discussed.
Reviewer Acknowledgements
Authors: Smith Robert 
Published: December 2018

Journal of Education and Training Studies (JETS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether JETS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 7, Number 1Adalberto Felipe Martinez, Federal University of São Carlos, BrazilArlene Kent, University of Saskatchewan, CanadaAyda Karaca, Hacettepe University, TurkeyBenmarrakchi Fatimaezzahra, Chouaib Doukkali University, MoroccoErsin Ture, Erzincan University, TurkeyFatma Çepikkurt, Mersin University, TurkeyFatmanur Ozen, Giresun University, TurkeyFroilan D. Mobo, Philippine Merchant Marine Academy, PhilippineIbrahim ERDEMIR, Balikesir University, Turkeyİbrahim Yaşar Kazu, Firat University, TurkeyJohn Bosco Azigwe, Bolgatanga Polytechnic, GhanaJohn Cowan, Edinburgh Napier University, UKKayhan Inan, Amasya University, TurkeyLaura Bruno, The College of New Jersey, USAMan-fung Lo, The Hong Kong Polytechnic University, Hong KongMatt Varacallo, University of Kentucky, USAMehmet Behzat Turan, Erciyes University, TurkeyMehmet Demirel, Necmettin Erbakan University, TurkeyMeral Seker, Alanya Alaaddin Keykubat University, TurkeyOsman Pepe, Erciyes University, Turkey,Özhan Bavlı, Çanakkale 18 Mart University, TurkeySadia Batool, Preston University Islamabad, PakistanSayim Aktay, Mugla Sitki Kocman University, TurkeySezgin Demir, Firat University, TurkeyStamatis Papadakis, University of Crete, GreeceZait Burak Aktuğ, Niğde Ömer Halis Demir University, Turkey Robert SmithEditorial AssistantOn behalf of,The Editorial Board of Journal of Education and Training StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://jets.redfame.com
Implementation of Routine HPV Vaccination in the Management of Recurrent Respiratory Papillomatosis
Authors: Yiu Yin , Fayson Shannon , Smith Holly , Matrka Laura 
Published: December 2018

Objectives: To investigate vaccine compliance and clinical outcomes after implementation of an initiative to provide the human papillomavirus (HPV) vaccine to all patients with recurrent respiratory papillomatosis (RRP). Methods: A retrospective review was performed of all adult patients treated for RRP from 2012 to 2017. Rates of HPV vaccination were evaluated before and after December 2015, when a program was established to increase compliance by educating patients and providing financial assistance toward vaccine administration. Paired sample analyses were conducted to compare intersurgical intervals (ISIs) and number of procedures per year pre- and post-vaccination. Results: Fourteen patients with RRP completed the HPV vaccine series, with 11 patients undergoing vaccination after the initiative began. The pre-initiative vaccination rate of all patients with RRP was 9.7%; post-initiative rates improved to 43.8% ( P = .004; odds ratio, 7.26). Of vaccinated patients, there were significant differences between mean pre-vaccine ISI (3.5 months) and post-vaccine ISI (12.8 months; P = .0021), as well as between number of surgical procedures performed per year before and after vaccination (2.7 vs 0.81; P = .014). After vaccination, 5 patients demonstrated no evidence of papilloma regrowth for >12 months. Conclusions: Initiatives focused on patient education and financial support can successfully boost HPV vaccination rates in an RRP patient cohort. Our research mirrors prior findings that HPV vaccination is correlated with an increase in time between procedures and a decrease in number of procedures needed per year—factors that can dramatically reduce the disease burden on patients coping with RRP.
Mental health indicators in APEC
Authors: Kron Michael , Grewal Rupinder , Idso John , Prough Michael , Sundaram Cassandra , Klein Scott , Nida John , Jumbam Desmond , Garringer Kaya 
Published: December 2018

Background: The World Economic Forum (2011) concluded that the economic impact of mental illness is the single most important contributor among all non-communicable diseases to loss of productivity. The 21 economies represented by Asia Pacific Economic Cooperation (APEC) responded to that information with efforts to address mental health as an integral component of economic development. Aim: In order to help assess the progress of APEC region compared to other regions of the world, the World Health Organization (WHO) granted us access to a subset of the 2014 Mental Health Atlas database containing health indicators from all 21 APEC economies. Methods: APEC-specific data were extracted using the same format used by WHO in its Mental Health Atlas to compare/contrast data in APEC versus the six WHO regions of the world. Results: It was observed that mental health workforces in APEC include a higher number of psychiatrist providers compared with WHO regions. Suicide rates reported in three APEC economies are among the highest in the world. All APEC economies continue their individual and coordinated efforts to support their ‘ APEC Roadmap to Promote Mental Wellness in a Healthy Asia Pacific (2014–2020)’. Conclusion: Significant challenges for APEC members exist to coordinate regional efforts to improve mental health due to highly variable income levels, existing health infrastructures and social preferences. The findings in this report may serve as a helpful baseline for measuring success within the APEC region by 2020, the year in which progress in support of economic development will be reassessed.
Comparing Usual Dietary Intakes Among Subgroups of Mothers in the Year Before Pregnancy
Authors: Carmichael Suzan L. , Ma Chen , Feldkamp Marcia L. , Shaw Gary M. ,   the National Birth Defects Prevention Study
Published: December 2018

Objective: The quantity and quality of dietary intake among women of reproductive age has important public health implications for nutritional status during pregnancy. We described dietary intake during the year before pregnancy among a large, diverse group of US mothers. Methods: We examined data from 11 109 mothers who gave birth from 1997 through 2011 and participated in a population-based case-control study, the National Birth Defects Prevention Study, as controls (mothers who had babies without major birth defects). We examined whether subgroups of mothers at elevated risk of adverse pregnancy outcomes were more likely than their reference groups to have high dietary intake (>90th percentile of intake) or low dietary intake (<10th percentile of intake). We examined dietary intake of 22 nutritional factors, which were estimated from responses to a food frequency questionnaire. Results: Participants who were aged <20, were nulliparous, had <high school diploma or <$20 000 annual household income, were non-Hispanic black, were underweight or obese, did not intend to become pregnant, did not take folic acid–containing vitamin supplements, or smoked had worse dietary intakes than their reference groups. For example, 17.5% of participants aged <20 had a low score on the diet quality index and 5.3% had a high score (vs expected values of 10%). Participants who were aged ≥35, were Hispanic, or had prepregnancy diabetes tended to have better dietary intakes than their reference groups. Maternal overweight and prepregnancy hypertension had few significant associations. Conclusions: Strategies are needed to ensure optimal nutrition among all childbearing women.
T-2 Toxin Induces Epiphyseal Plate Lesions via Decreased SECISBP2-Mediated Selenoprotein Expression in DA Rats, Exacerbated by Selenium Deficiency
Authors: Sun Jian , Min Zixin , Zhao Wenxiang , Hussain Safdar , Zhao Yitong , Guo Dongxian , Zhang Fujun , Guo Yuanxu , Sun Mengyao , Huang Huang , Han Yan , Zhong Nannan , Xu Peng , Lu Shemin 
Published: December 2018

Objective Both selenium (Se) deficiency and mycotoxin T2 lead to epiphyseal plate lesions, similar to Kashin-Beck disease (KBD). However, regulation of selenoproteins synthesis mediated by SECISBP2, in response to these 2 environmental factors, remained unclear. The present study proposed to explore the mechanism behind the cartilage degradation resulting from Se deficiency and mycotoxin T2 exposure. Design Deep chondrocyte necrosis and epiphyseal plate lesions were replicated in Dark Agouti (DA) rats by feeding them T2 toxin/Se deficiency artificial synthetic diet for 2 months. Results Se deficiency led to decreased expression of COL2α1, while T2 treatment reduced the heparan sulfate 6-O-sulfotransferase 2 (HS6ST2) expression, both of which affected the cartilage extracellular matrix metabolism in the rat models. The expression of Col2α1, Acan, Hs6st2, Secisbp2, Gpx1, and Gpx4 were all significantly decreased in cartilage tissues from DA rats, fed a Se-deficient diet or exposed to T2 toxin, contrary to Adamts4, whose expression was increased in both conditions. In addition, T2 treatment led to the decreased expression of SBP2, GPX1, GPX4, and total GPXs activity in C28/I2 cells. Conclusion DA rats exposed to T2 toxin and/or Se-deficient conditions serve as the perfect model of KBD. The 2 environmental risk factors of KBD, which serve as a “double whammy,” can intensify the extracellular matrix metabolic imbalance and the antioxidant activity of chondrocytes, leading to articular cartilage degradation and epiphyseal plate abnormalities similar to those observed in KBD.
Effect of Activity at Time of Injury and Concomitant Ligament Injuries on Patient-Reported Outcome After Posterior Cruciate Ligament Reconstruction
Authors: Owesen Christian , Røtterud Jan-Harald , Engebretsen Lars , Årøen Asbjørn 
Published: December 2018

Background: The outcomes after posterior cruciate ligament reconstruction (PCLR) have been shown to be inferior to those of anterior cruciate ligament reconstruction. There is a lack of knowledge regarding prognostic factors of PCLR outcomes. Purpose: To explore the effect of injury mechanism and concomitant ligament injuries on patient-reported outcomes at 2-year follow-up after PCLR. Study Design: Cohort study; Level of evidence, 2. Methods: A total of 373 patients who underwent primary PCLR and who were registered in the Norwegian Knee Ligament Registry were included. The Knee injury and Osteoarthritis Outcome Score (KOOS) was used as the patient-reported outcome measure. At 2-year follow-up, 252 patients (68%) had completed the KOOS. Multiple regression analysis was used to evaluate the effects of injury activity and multiligament injuries on the KOOS outcomes. Results: In the adjusted and unadjusted regression analyses, patients injured during sports reported significantly better outcome at 2-year follow-up after PCLR than patients injured during other activities ( P < .001) according to all KOOS subscales. Adjusted analysis was as follows for the KOOS subscales: Symptoms (regression coefficient [β], 7.0; 95% CI, 1.9-12.2), Pain (β, 13.4; 95% CI, 8.0-18.9), Activities of Daily Living (β, 12.6; 95% CI, 7.1-18.1), Sport/Recreation (β, 15.3; 95% CI, 8.0-22.5), and Quality of Life (β, 13.5; 95% CI, 7.1-20.0). In the unadjusted analysis, patients with isolated PCL injuries reported higher scores in the Sport/Recreation subscale (β, –7.9; 95% CI, –15.5 to –0.3). The difference was not significant in the adjusted analysis. No other significant differences in KOOS outcomes were found between isolated and multiligament injuries. Conclusion: Patients injured in sports reported better outcomes at 2 years after PCLR as compared with patients injured in other activities. Multiligament injuries involving the PCL do not seem to predict a worse outcome than for isolated PCL injuries.
Incidence, mortality, and temporal patterns of oropharyngeal cancer in China: a population‐based study
Authors: Liu Jie , Yang Xu‐li , Zhang Si‐Wei , Zhu Li‐Ping , Chen Wan‐Qing 
Published: December 2018

AbstractBackgroundThus far, the incidence, mortality, and temporal trend data of oropharyngeal cancers (OPC) in China were few. We estimated the incidence, mortality, and temporal patterns of OPC in China during 2008–2012 according to the data from 135 population‐based cancer registries to better understand the epidemiological pattern of OPC and to provide more precise information for OPC control in China.MethodsAccording to the data of diagnosed OPC reported to 135 cancer registries during 2008–2012, we calculated age‐standardized rate of incidence and mortality by 2000 Chinese standard population (ASRIC and ASRMC) and by 1985 Segi's world standard population (ASRIW and ASRMW) by age, sex, and geographic regions; annual percentage changes of OPC incidence and mortality were calculated using Joinpoint trend analysis.ResultsASRIW and ASRMW were 2.22/100,000 person‐years and 0.94/100,000 person‐years, respectively. The incidence and mortality in urban areas were higher than those in rural areas. ASRIC and ASRIW of males were higher than those of females. The overall ASRIC of OPC was significantly increased by 6.2% annually between 2003 and 2006 (P = 0.038), but remained stable between 2007 and 2012 (P = 0.392). ASRIC and ASRMC of males and in rural areas were significantly increased in the last decade (P < 0.05), but the rates of females remained stable during the same period (P > 0.05).ConclusionsAcross multiple cancer registries in China, there was an obvious increase in OPC in the recent decade, especially for incidence and mortality of males and in rural areas, whereas the rates of females remained stable. A healthy lifestyle should be advocated and early diagnosis and early treatment of OPC should be enhanced.
Interferon-Inducible Myxovirus Resistance Proteins: Potential Biomarkers for Differentiating Viral from Bacterial Infections
Authors: Zav'yalov Vladimir P , Hämäläinen-Laanaya Heli , Korpela Timo K , Wahlroos Tony 
Published: December 2018

AbstractBACKGROUNDIn 2015, the 68th World Health Assembly declared that effective, rapid, low-cost diagnostic tools were needed for guiding optimal use of antibiotics in medicine. This review is devoted to interferon-inducible myxovirus resistance proteins as potential biomarkers for differentiating viral from bacterial infections.CONTENTAfter viral infection, a branch of the interferon (IFN)-induced molecular reactions is triggered by the binding of IFNs with their receptors, a process leading to the activation of mx1 and mx2, which produce antiviral Mx proteins (MxA and MxB). We summarize current knowledge of the structures and functions of type I and III IFNs. Antiviral mechanisms of Mx proteins are discussed in reference to their structural and functional data to provide an in-depth picture of protection against viral attacks. Knowing such a mechanism may allow the development of countermeasures and the specific detection of any viral infection. Clinical research data indicate that Mx proteins are biomarkers for many virus infections, with some exceptions, whereas C-reactive protein (CRP) and procalcitonin have established positions as general biomarkers for bacterial infections.SUMMARYMx genes are not directly induced by viruses and are not expressed constitutively; their expression strictly depends on IFN signaling. MxA protein production in peripheral blood cells has been shown to be a clinically sensitive and specific marker for viral infection. Viral infections specifically increase MxA concentrations, whereas viruses have only a modest increase in CRP or procalcitonin concentrations. Therefore, comparison of MxA and CRP and/or procalcitonin values can be used for the differentiation of infectious etiology.
Current account determinants in ASEAN 6
Authors: Ariyani Novi , Priyanto Fajar Wahyu , Yuliati Lilis 
Published: December 2018

This study aims to analyze the factors that influence the export activity in the ASEAN region countries such as Indonesia, Singapore, Thailand, Malaysia, Philippines and Vietnam during 2001 - 2016 by using annual data.Â The factors that influence gross domestic product (GDP), interest rate, foreign direct investment (FDI) and exchange rate.Â The method used in the research is panelÂ Vector Error Correlation ModelÂ (PVECM).Â The results show that Gross Domestic Product (GDP) negatively affects the current account in the short term.Â The interest rate variable negatively affects the current account in the long term.Â The Foreign Direct Investment (FDI) variable negatively affects the current account in the long term.Â Furthermore, the exchange rate variable negatively affects the current account in the long term.
Motivation Scale For Participation In Physical Activity (MSPPA): A study of validity and reliability<p>Fiziksel Aktiviteye Katılım Motivasyonu Ölçeği (FAKMÖ): Geçerlik ve güvenirlik çalışması
Authors: Tekkurşun Demir Gönül , Cicioğlu Halil İbrahim 
Published: December 2018

The aim of this study is to develop a valid and reliable measurement tool to measure the motivation of high school students to participate in physical activity. In the study, the relevant literature was searched and focus group interview was made with three different groups composed of 8 high school students, and an item pool with 55-item was created considering the opinions of experts. After the expert opinions were received, necessary corrections were made on the test form and applied to 308 high school students attending Ödemiş Anatolian High School and Ödemiş Ticaret Odası Anatolian High School in Ödemiş, İzmir in 2016-2017 academic year. As a result of the exploratory factor analysis, the form, which is formed by 16 items and 3 sub-dimensions, accounts for 54.69% of the total variance. In the result of the CFA, the values of fit indices were examined and it was seen that the 3 factorial structure of the scale consisting of 16 items was confirmed as a model. The scale was found to be reliable according to Cronbach's Alfa internal consistency tested to determine the reliability of the scale and the Spearman Brown two-tailed reliability coefficient values. As a result, it was concluded that the "Motivation Scale For Participation In Physical Activity (MSPPA)" is valid and reliable.Extended English summary is in the end of Full Text PDF (TURKISH) file. ÖzetBu çalışmanın amacı, lise öğrencilerinin fiziksel aktiviteye katılım motivasyonlarını ölçebilmek için geçerli ve güvenilir bir ölçme aracı geliştirmektir. Çalışmada ilgili literatür taranmış, üç farklı gruptan oluşan 8’er lise öğrencisi ile odak grup görüşmesi yapılmış ve uzman görüşleri göz önünde bulundurularak 55 maddelik bir madde havuzu oluşturulmuştur. Uzman görüşleri alındıktan sonra denemelik form üzerinde gerekli düzeltmeler yapılmış ve 2016-2017 eğitim öğretim yılında İzmir ili Ödemiş ilçesinde Ödemiş Anadolu Lisesi ve Ödemiş Ticaret Odası Anadolu Lisesi’nde öğrenimine devam eden 308 lise öğrencisine uygulanmıştır. Açımlayıcı faktör analizi sonucunda, 16 madde ve 3 alt boyuttan oluştuğu tespit edilen form, toplam varyansın %54,69’unu açıklamaktadır. Yapılan DFA sonucunda da uyum indeks değerlerine bakılmış ve 16 maddeden oluşan ölçeğin 3 faktörlü yapısının bir model olarak doğrulandığı görülmüştür. Ölçeğin güvenirliğini belirlemek için test edilen Cronbach-Alfa iç tutarlık ve Spearman Brown iki yarı güvenirlik katsayı değerlerine göre ölçeğin güvenilir olduğu sonucuna varılmıştır. Sonuç olarak, “Fiziksel Aktiviteye Katılım Motivasyonu Ölçeği (FAKMÖ)” nin geçerli ve güvenilir olduğu sonucuna varılmıştır.