bluuebunny/crossref_metadata_2025_split huggingface dataset:
Defoliation of a grass is mediated by the positive effect of dung deposition, moss removal and enhanced soil nutrient contents: results from a reindeer grazing simulation experiment
Authors: Barthelemy Hélène , Dorrepaal Ellen , Olofsson Johan 
Published: June 2019

Herbivory is one of the key drivers shaping plant community dynamics. Herbivores can strongly influence plant productivity directly through defoliation and the return of nutrients in the form of dung and urine, but also indirectly by reducing the abundance of neighbouring plants and inducing changes in soil processes. However, the relative importance of these processes is poorly understood.We, therefore, established a common garden experiment to study plant responses to defoliation, dung addition, moss cover, and the soil legacy of reindeer grazing. We used an arctic tundra grazed by reindeer as our study system, and Festuca ovina, a common grazing‐tolerant grass species as the model species.The soil legacy of reindeer grazing had the strongest effect on plants, and resulted in higher growth in soils originating from previously heavily‐grazed sites. Defoliation also had a strong effect and reduced shoot and root growth and nutrient uptake. Plants did not fully compensate for the tissue lost due to defoliation, even when nutrient availability was high. In contrast, defoliation enhanced plant nitrogen concentrations. Dung addition increased plant production, nitrogen concentrations and nutrient uptake, although the effect was fairly small. Mosses also had a positive effect on aboveground plant production as long as the plants were not defoliated. The presence of a thick moss layer reduced plant growth following defoliation.This study demonstrates that grasses, even though they suffer from defoliation, can tolerate high densities of herbivores when all aspects of herbivores on ecosystems are taken into account. Our results further show that the positive effect of herbivores on plant growth via changes in soil properties is essential for plants to cope with a high grazing pressure. The strong effect of the soil legacy of reindeer grazing reveals that herbivores can have long‐lasting effects on plant productivity and ecosystem functioning after grazing has ceased.
Case report: Cryoballoon ablation of the mitral isthmus using a novel mapping system
Authors: Badertscher Patrick , Wissner Erik 
Published: June 2019

AbstractPerimitral atrial flutter is commonly treated by deployment of a mitral isthmus line. However, the creation of a contiguous, transmural linear lesion across the anterior mitral isthmus using radiofrequency energy ablation is technically challenging and can be associated with major complications. Herein, we describe the successful deployment of a superolateral mitral isthmus line using the 28‐mm cryoballoon in combination with a new mapping system.
Towards semantic‐aware multiple‐aspect trajectory similarity measuring
Authors: Petry Lucas May , Ferrero Carlos Andres , Alvares Luis Otavio , Renso Chiara , Bogorny Vania 
Published: June 2019

AbstractThe large amount of semantically rich mobility data becoming available in the era of big data has led to a need for new trajectory similarity measures. In the context of multiple‐aspect trajectories, where mobility data are enriched with several semantic dimensions, current state‐of‐the‐art approaches present some limitations concerning the relationships between attributes and their semantics. Existing works are either too strict, requiring a match on all attributes, or too flexible, considering all attributes as independent. In this article we propose MUITAS, a novel similarity measure for a new type of trajectory data with heterogeneous semantic dimensions, which takes into account the semantic relationship between attributes, thus filling the gap of the current trajectory similarity methods. We evaluate MUITAS over two real datasets of multiple‐aspect social media and GPS trajectories. With precision at recall and clustering techniques, we show that MUITAS is the most robust measure for multiple‐aspect trajectories.
Chinese poultry farmers' decision‐making for avian influenza prevention: a qualitative analysis
Authors: Cui Bin , Wang Linda Dong‐Ling , Ke Jun , Tian Yi 
Published: June 2019

AbstractPoultry farmers faced dual risk when mutant avian influenza (AI) virus showed the zoonotic characteristics. A/H5N1 and A/H7N9 were two dominant AI virus strains that have captured the attention of the public over the years for they have been reported to bring about greater loss to poultry and human, respectively. Previous studies mainly used quantitative methods investigating either the means that poultry farmers adopted for protecting their poultry against A/H5N1 infection or the poultry farmers' self‐protective behaviours against A/H7N9 infection. We sought insights into the underlying factors influencing Chinese poultry farmers' protective behaviours in response to the dual risk of AI by a qualitative way. Semi‐structured in‐depth interviews were conducted with 25 Chinese chicken farmers recruited by purposive sampling between November 2016 and May 2017, the peak season of AI. All interviews were audio‐taped, transcribed and analysed using a grounded theory approach. From participants' experiences, we revealed five main themes: Measures adopted for protecting poultry and farmers, Emotional response to the AI epidemic, Perceived risk of AI, Perceived effectiveness of the preventive measures adopted and Perceived self‐efficacy to take preventive measures. The information of AI outbreak directly triggered Chinese chicken farmers' emotional response and thereafter preventive actions. Compared to the perceived risk of poultry infection with A/H5N1 which mainly connected to economic loss, participants perceived much lower risk of human infection with A/H7N9. AI epidemic information played a key role triggering poultry farmers' response behaviours. Chinese poultry farmers weighted more attention on the risk of poultry infection which was highly associated with economic losses. The government should build and improve an early AI warning and information transmission network to poultry farmers. Further reinforcement of related self‐protective and preventive knowledge training towards poultry farmers is necessary.
Climate impact on fluvial-lake system evolution, Eocene Green River Formation, Uinta Basin, Utah, USA
Authors: Birgenheier L.P. , Berg M.D. Vanden , Plink-Björklund P. , Gall R.D. , Rosencrans E. , Rosenberg M.J. , Toms L.C. , Morris J. 
Published: June 2019

AbstractIn light of a modern understanding of early Eocene greenhouse climate fluctuations and new highly seasonal fluvial system faces models, the role of climate in the evolution of one classically-cited continental, terminal lake system is re-examined. Detailed stratigraphic description and elemental abundance data from fifteen cores and seven outcrop regions of the Green River Formation were used to construct a ∼150 km cross section across the Uinta Basin, Utah, USA. Lake Uinta in the Uinta Basin is divided into five lake phases: (1) post-Paleocene Eocene Thermal Maximum, (2) peak Eocene hyperthermal, (3) waning hyperthermal, Early Eocene Climatic Optimum (EECO), (4) post-hyperthermal, and (5) post-EECO regimes, based primarily on climatically driven changes in fluvial style in combination with sedimentary indicators of lacustrine carbonate deposition, organic matter preservation, salinity, and lake depth. Basinwide siliciclastic dominated intervals were deposited by highly seasonal fluvial systems and record negative organic carbon isotope excursions associated with early Eocene abrupt, transient global warming (hyperthermal) events. Carbonate dominated or organic rich intervals record stable, less seasonal climate periods between hyperthermals, with lower siliciclastic sediment supply allowing the development of carbonate and organic matter preservation. The stratigraphic progression from alternating organic rich and lean zones to the overlying organic rich Mahogany and R8 zones represents the global transition out of the pulsed early Eocene hyperthermal climate regime to a time of sediment starvation and lake stratification, sequestering sedimentary organic carbon. This study provides a novel approach to terrestrial paleoclimate reconstruction that relies largely on unique sedimentary indicators and secondarily on isotopic proxy records within the context of a large basin-wide sedimentologic and stratigraphic data set, thus setting the stage for future detailed geochemical terrestrial paleoclimate proxy development.
P015 Yellow cards are still not on everyone’s to do list
Authors: Horan Emily , Tuthill David 
Published: June 2019

AimTo look at how the Yellow Card Scheme is used by health care professionals (HCPs) in child health.MethodsAn online SurveyMonkey questionnaire was devised to look at how healthcare professionals (HCPs) have used the Yellow Card Scheme in clinical practice. It comprised of 10 questions (9 multiple choice and 1 freestyle text). What type of healthcare professional are you? Are you aware of the Yellow Card reporting scheme? Have you ever used the Yellow Card Scheme to report an adverse drug reaction? If yes, how did you make the report? (If no, select N/A) If you haven’t ever reported a reaction, would you know how to? Have you ever completed an e learning module about the Yellow Card Scheme? Are you aware that parents can report adverse drug reactions using the Yellow Card Scheme? Have you ever been aware of an adverse drug reaction but decided not to report it? If yes, what was the reason you chose not to report it? (If no, select N/A) Can you think of any ways to make the Yellow Card Scheme more accessible to healthcare professionals? It was piloted on 5 HCPS and minor textural revisions made. The questionnaire was then undertaken via face-to-face interviews during June 2018.Results50 healthcare professionals completed the questionnaire: 16 doctors, 13 nurses, 8 pharmacists, 9 medical students, 2 nursing students and 2 pharmacy technicians. 43/50 were aware of the Yellow Card Scheme (10 undergraduates and 33 postgraduates). 18 participants had used the Yellow Card whilst 32 had not reported an adverse drug event. Out of the 32 respondents who had never reported a reaction, 13 (7 undergraduates and 6 postgraduates) said that they would not know how to report a reaction if required. Only 9 had completed an online e learning module about the Yellow Card scheme. 30 participants were aware that parents could report using the scheme. 10 participants had been aware of an adverse drug reaction but decided not to report it. The most common reason for this was being too busy. The most common suggestion on how to improve accessibility to the Yellow Card Scheme was the implementation of a mobile phone application.ConclusionMost participants were aware of the Yellow Card scheme although undergraduates less so. Many had reported, although some had chosen not to report because they were: too busy; not being concerned enough; not knowing how to; having forgotten. An app already exists, but awareness of this appears low, as it was the commonest suggestion to aid the low reporting.
P051 The bigger you are the harder you fall? Short term effects of LUM/IVA (Orkambi) on lung function in children with cystic fibrosis
Authors: Grady Emma O’ , Finnegan Rebecca , Smyth Anna , Ryan Stephanie , Williamson Michael 
Published: June 2019

AimCystic Fibrosis conductance Transmembrane Regulator (CFTR) protein modulators represent a major breakthrough in the pharmacological management of Cystic Fibrosis (CF). Previous studies report acute changes in lung function after first administration of lumacaftor/ivacaftor (LUM/IVA) without a clear underlying mechanism.1 2 Our aim was to explore links between changes in percent predicted forced expiratory volume in one second (ppFEV1) and a number of potentially influencing factors.MethodsWe conducted a retrospective review of all children with CF who were started on LUM/IVA treatment between September 2016 and August 2017 in our institution. Data was collected from patient charts, electronic laboratory and radiology records. CT Thorax images were reviewed for evidence of air trapping using the Brody score.3 Descriptive and statistical analyses were performed using SPSS. ResultsData was collected from 15 children with CF who were started on LUM/IVA treatment. The mean (±SD) age of starting treatment was 14 years (±1.7 years), with a mean weight of 47.3 kg (±8.9 kg) and male-to-female ratio of 9:6. Ninety-three percent of patients experienced an acute decline in ppFEV1 post initiation of LUM/IVA, with an absolute mean decline of -10.8% (0–20%). There is a statistically significant inverse relationship between absolute change in ppFEV1 (FEV1) and baseline ppFEV1. There is no correlation between FEV1 and weight, gender or air trapping score.ConclusionOur results suggest that a LUM/IVA related decline in lung function is more significant in CF children with higher baseline ppFEV1. This offers reassurance when initiating LUM/IVA as the patients who experience significant declines have a greater respiratory reserve with which to support this reduction. ReferencesRatjen F, Hug C, Marigowda G, et al. Efficacy and safety of lumacaftor and ivacaftor in patients aged 6–11 years with cystic fibrosis homozygous for F508del-CFTR: a randomised, placebo-controlled phase 3 trial. Lancet Respir Med 2017;5:557–567.Labaste A, Ohlmann C, Mainguy C, et al. Real-life acute lung function changes after lumacaftor/ivacaftor first administration in paediatric patients with cystic fibrosis. J Cyst Fibros 2017;16:709–712.Brody A, Klein J, Molina P, et al. High- resolution computed tomography in young patients with cystic fibrosis: distribution of abnormalities and correlation with pulmonary function tests. Journal of Pediatrics 2004;145:32–38.
Survey of the effect of viewing an online e-cigarette advertisement on attitudes towards cigarette and e-cigarette use in adults located in the UK and USA: a cross-sectional study
Authors: Booth Paula , Albery Ian P , Cox Sharon , Frings Daniel 
Published: June 2019

ObjectivesThis study explored the potential for e-cigarette advertisements to (1) enhance attitudes towards cigarettes and/or (2) reduce barriers to e-cigarettes uptake. The study tested whether exposure to an online electronic cigarette advertisement changed attitudes towards cigarettes and e-cigarettes in smokers, non-smokers, e-cigarette users and dual users (smokers who also use e-cigarettes).DesignCross-sectional studySettingOnline surveyParticipantsAdults (n=964) aged 18 to 65 years old (M=36 years, SD=11.6) from the UK and USA. Participants were grouped into current non-smokers, e-cigarette users, dual users and smokers.InterventionsParticipants viewed 1 of 15 randomly assigned online e-cigarette advertisements.Primary measuresThree single seven-point Likert scales measuring health, desirability, social acceptability were completed pre and post advertisement exposure.ResultsPost exposure all smoking groups showed a decrease or no change in how socially acceptable or desirable they rated cigarettes. Paradoxically, dual users rated cigarettes as being significantly healthier after viewing the advertisement (p=0.01) while all other smoking group ratings remained the same. There was an increase or no change in how all smoking groups perceived the healthiness and desirability of e-cigarettesConclusionsWe observed no evidence that exposure to an e-cigarette advertisement renormalises or encourages smoking in smokers, non-smokers or e-cigarette users. However, there is some indication that viewing an e-cigarette advertisement may increase duals users’ perceptions of the health of smoking.
First responder communication in CBRN environments: FIRCOM-CBRN study
Authors: Schumacher Jan , Arlidge James , Dudley Declan , Van Ross Jennifer , Garnham Francesca , Prior Kate 
Published: June 2019

IntroductionRecent terror attacks and assassinations involving highly toxic chemical weapons have stressed the importance of sufficient respiratory protection of medical first responders and receivers. As full-face respirators cause perceptual-motor impairment, they not only impair vision but also significantly reduce speech intelligibility. The recent introduction of electronic voice projection units (VPUs), attached to a respirator, may improve communication while wearing personal respiratory protection.ObjectiveTo determine the influence of currently used respirators and VPUs on medical communication and speech intelligibility.Methods37 trauma anaesthetists carried out an evaluation exercise of six different respirators and VPUs including one control. Participants had to listen to audio clips of a variety of sentences dealing with scenarios of emergency triage and medical history taking.ResultsIn the questionnaire, operators stated that speech intelligibility of the Avon C50 respirator scored the highest (mean 3.9, ±SD 1.0) and that the Respirex Powered Respiratory Protective Suit (PRPS) NHS-suit scored lowest (1.6, 0.9). Regarding loudness the C50 plus the Avon VPU scored highest (4.1, 0.7), followed by the Draeger FPS-7000-com-plus (3.4, 1.0) and the Respirex PRPS NHS-suit scored lowest (2.3, 0.8).ConclusionsWe found that the Avon C50 is the preferred model among the tested respirators. In our model, electronic voice projection modules improved loudness but not speech intelligibility. The Respirex PRPS NHS-suit was rated significantly less favourably in respect of medical communication and speech intelligibility.
Measuring experience and outcomes in patients reporting sexual violence who attend a healthcare setting: a systematic review
Authors: Caswell Rachel J , Ross Jonathan DC , Lorimer Karen 
Published: June 2019

BackgroundObtaining perspectives from those seeking healthcare after sexual violence on care and how it is delivered is important.ObjectivesTo systematically identify any existing patient-reported outcome and experience measures (PROMs and PREMs) for patients attending healthcare services after sexual violence. Also, to identify key themes regarded by patients as priorities for delivering a high-quality service.DesignSystematic review (PROSPERO registration RD42016050297).Data sourcesEight electronic bibliographic databases from inception to March 2017. ‘Grey’ literature also searched. Search words included patient view, patient experience, PROM/PREM, sexual violence, rape.Review methodsStudies of any design, with participants of any gender and aged 13 years or older were included; studies only assessing the views of service providers were excluded. Appraisal tools assessed for study quality. Healthcare outcome data were assessed across the quantitative studies and key experiences across qualitative papers; Framework Analysis was used to synthesise the qualitative studies.ResultsFrom 4153 identified papers, 20 fulfilled criteria for inclusion: 10 qualitative, 8 quantitative and 2 mixed methods. No validated measure of assessing patient experience or outcome was identified. The synthesis of qualitative studies led to the assignment of two overarching themes around the importance of patient-focused and trauma-focused communication, and of care which enhances patient empowerment. A paucity of research within certain patient groups who experience sexual violence, in particular men and LGBT (lesbian, gay, bisexual and trans) patients was noted.LimitationsA broad definition of ‘healthcare setting’ incorporated a wide variety of venues limiting the applicability of findings in specific settings.ConclusionA validated and standardised approach to assess patient experience and outcome in healthcare settings after sexual violence is needed. Themes identified should be incorporated into PROM or PREM development. The review also suggests the need for a change in approach towards those who attend for healthcare after sexual violence to ensure patient autonomy.
Cohort Study of Repeated Measurements of Serum Urate and Risk of Incident Atrial Fibrillation
Authors: Li Shanshan , Cheng Jin , Cui Liufu , Gurol M. Edip , Bhatt Deepak L. , Fonarow Gregg C. , Benjamin Emelia J. , Xing Aijun , Xia YunLong , Wu Shouling , Gao Xiang 
Published: June 2019

Background

Current evidence on the association between serum urate and risk of atrial fibrillation (
AF
) is limited by cross‐sectional designs and 1‐time measurement of serum urate. The roles of serum urate, gout‐related inflammation, and systemic inflammation in the etiology of
AF
are currently unknown. This gap is important, given that systemic inflammation is a recognized risk factor for
AF
.

Methods and Results

We conducted a prospective cohort study of 123 238 Chinese patients from 2006 to 2014. Serum urate concentrations were measured in 2006, 2008, 2010, and 2012. Incident
AF
cases were identified via biennial 12‐lead ECG assessment. We used a Cox proportional hazards model to examine the sex‐specific associations of cumulative average serum urate and changes in serum urate accounting for baseline level with risk of incident
AF
. We also assessed the joint associations of serum urate and high‐sensitivity C‐reactive protein levels. Comparing extreme categories, participants with the highest quintile of serum urate had 1.91‐fold higher risk of
AF
(adjusted hazard ratio: 1.91; 95% CI, 1.32–2.76;
P
=0.001 for trend). Participants with both high serum urate and high‐sensitivity C‐reactive protein had 2.6‐fold elevated risk of incident
AF
compared with those with normal levels of serum urate and high‐sensitivity C‐reactive protein (adjusted hazard ratio: 2.63; 95%
CI,
1.63–4.23).

Conclusions

High serum urate levels and increases in serum urate over time were associated with increased risk of incident
AF
. Patients with high levels of both serum urate and high‐sensitivity C‐reactive protein had substantially higher risk of
AF
.
Attention-Passing Models for Robust and Data-Efficient End-to-End Speech Translation
Authors: Sperber Matthias , Neubig Graham , Niehues Jan , Waibel Alex 
Published: June 2019

Speech translation has traditionally been approached through cascaded models consisting of a speech recognizer trained on a corpus of transcribed speech, and a machine translation system trained on parallel texts. Several recent works have shown the feasibility of collapsing the cascade into a single, direct model that can be trained in an end-to-end fashion on a corpus of translated speech. However, experiments are inconclusive on whether the cascade or the direct model is stronger, and have only been conducted under the unrealistic assumption that both are trained on equal amounts of data, ignoring other available speech recognition and machine translation corpora. In this paper, we demonstrate that direct speech translation models require more data to perform well than cascaded models, and although they allow including auxiliary data through multi-task training, they are poor at exploiting such data, putting them at a severe disadvantage. As a remedy, we propose the use of end- to-end trainable models with two attention mechanisms, the first establishing source speech to source text alignments, the second modeling source to target text alignment. We show that such models naturally decompose into multi-task–trainable recognition and translation tasks and propose an attention-passing technique that alleviates error propagation issues in a previous formulation of a model with two attention stages. Our proposed model outperforms all examined baselines and is able to exploit auxiliary training data much more effectively than direct attentional models.