bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of ENSO on the distribution and concentration of catches and reproductive activity of anchovy Engraulis ringens in northern Chile
Authors: Hernández‐Santoro Carola , Landaeta Mauricio F. , Castillo Pizarro Jorge 
Published: September 2018

AbstractAnchovy makes up 90% of pelagic fishery catches in northern Chile. For the present work, anchovy (Engraulis ringens, Jenyns 1842) catches between 1997 and 2016 were analyzed to determine changes in distribution, concentration, and reproductive behavior before, during, and after ENSO events, using spatial indexes: gravity center (GC), inertia, coverage (CI), Gini index, and gonadosomatic index (GI). At the start of ENSO, anchovy catches increased and concentrated along the coast (rising Gini index), while CI decreased. During ENSO, Gini decreased, registering a southward displacement of the GC and smaller catches. In the long run, anchovy occupied lesser area (<CI) starting from 2008, concentrating in coastal areas. It developed a size structure composed mainly of specimens smaller than 17.0 cm. In addition, specimens < 12.0 cm were positively correlated with thermal anomalies, CI and MEI, reaching more than 60% of the catches during the 1997–1998 and 2015–2016 ENSO cycles. Results suggest that the warm phase of ENSO alters the anchovies’ reproductive activity, delaying its onset up to 4 weeks, and reducing GI intensity to 50%, due to increased participation in the reproductive process of individuals 12.0–13.5 cm. Therefore, large‐scale environmental processes, such as ENSO, significantly affect size structure and contribute to reduction of occupied area and higher reproductive activity of small‐size anchovies.
How is biodiversity protection influencing the potential for bioenergy feedstock production on grasslands?
Authors: Hansson Julia , Berndes Göran , Englund Oskar , De Freitas Flávio L. M. , Sparovek Gerd 
Published: September 2018

AbstractSustainable feedstock supply is a critical issue for the bioenergy sector. One concern is that feedstock production will impact biodiversity. We analyze how this concern is addressed in assessments of biomass supply potentials and in selected governance systems in the EU and Brazil, including the EU Renewable Energy Directive (RED), the EU Common Agricultural Policy (CAP), and the Brazilian Forest Act. The analysis focuses on grasslands and includes estimates of the amount of grassland area (and corresponding biomass production volume) that would be excluded from cultivation in specific biodiversity protection scenarios. The reviewed assessments used a variety of approaches to identify and exclude biodiverse grasslands as unavailable for bioenergy. Because exclusion was integrated with other nature protection considerations, quantification of excluded grassland areas was often not possible. The RED complements and strengthens the CAP in terms of biodiversity protection. Following the RED, an estimated 39%–48% (about 9–11 Mha) and 15%–54% (about 10–38 Mha) of natural and non‐natural grassland, respectively, may be considered highly biodiverse in EU‐28. The estimated biomass production potential on these areas corresponds to some 1–3 and 1.5–10 EJ/year for natural and non‐natural grassland, respectively (depending on area availability and management intensity). However, the RED lacks clear definitions and guidance, creating uncertainty about its influence on grassland availability for bioenergy feedstock production. For Brazil, an estimated 16%–77% (about 16–76 Mha) and 1%–32% (about 7–24 Mha) of natural and non‐natural grassland, respectively, may be considered highly biodiverse. In Brazil, ecological–economic zoning was found potentially important for grassland protection. Further clarification of grassland definitions and delineation in regulations will facilitate a better understanding of the prospects for bioenergy feedstock production on grasslands, and the impacts of bioenergy deployment on biodiversity.
Universities’ attractiveness to students: The Darwinism effect
Authors: Cattaneo Mattia , Horta Hugo , Malighetti Paolo , Meoli Michele , Paleari Stefano 
Published: September 2018

AbstractDue to significant government cuts to Higher Education funding in Southern European systems, their already underfunded universities were forced to increasingly compete for students as sources of additional revenue. Concurrently, families and students that continued to afford participation in Higher Education became more selective when choosing a university, realising the riskier investment that Higher Education participation had become. Through a competing destinations model and relying on all Italian private and public universities, this study finds that the competition forces characterising universities’ attractiveness over the last decade have changed since the financial crisis of 2008. In a context of lower demand for Higher Education, the competition for students grew and universities in close proximity were better prepared to face the new challenges, leading to the growth of Higher Education clusters.
WhatsApp platforms in tropical public health resource‐poor settings
Authors: Hogan Sarah C. , van Hees Colette , Asiedu Kingsley B. , Fuller L. Claire 
Published: September 2018

AbstractIn order to deliver equal healthcare access to resource‐poor settings, sustainable, cost‐effective systems of communication should be used. As mobile phone use increases, remote care can be delivered via teledermatology using Apps. This commentary covers how WhatsApp could be used by dermatologists seeking to deliver healthcare in this context.
Clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated 9‐mediated mutagenesis of the multiple edematous wings gene induces muscle weakness and flightlessness in Bactrocera dorsalis (Diptera: Tephritidae)
Authors: Zheng W. , Li Q. , Sun H. , Ali M. Waqar , Zhang H. 
Published: September 2018

AbstractThe clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR‐associated 9 (Cas9) system is a versatile, efficient and heritable gene editing tool that can be useful for genome engineering. Bactrocera dorsalis (Hendel) is a major pest of agriculture that causes great economic losses. We used the B. dorsalis multiple edematous wings (Bdmew) gene as the target gene to explore the effectiveness of CRISPR/Cas9 for B. dorsalis genome manipulation. We studied the physiological functions of the Bdmew gene, particularly those related to muscle development. Site‐specific genome editing was feasible using direct microinjection of specific guide RNA and the Cas9‐plasmid into B. dorsalis embryos. Mutation frequencies ranged from 12.1 to 30.2% in the injected generation. Mosaic G0, with the mew mutation, was heritable to the next generation. The G1 displayed a series of defective phenotypes including muscle weakness, flightlessness, failure to eclose, wing folds and unbalanced movement. These results demonstrated that CRISPR/Cas9 can act as a highly specific, efficient, heritable tool for genome manipulation in B. dorsalis and this has significance for gene function research and genetic control of pests. The Bdmew gene possesses key functions in muscle development of B. dorsalis. Bdmew mutations cause a series of serious defects by interfering with muscle development and may provide a means for controlling B. dorsalis via a gene‐based method such as gene drive.
Updates on T helper type 17 immunity in respiratory disease
Authors: Iwanaga Naoki , Kolls Jay K. 
Published: September 2018

SummaryInterleukin‐17 (IL‐17)‐producing cells play a critical role in mucosal immunity including the respiratory tract. This review will highlight recent advances in our understanding of these cells in mucosal immunity in the lung as well as their potential pathogenic roles in respiratory diseases. The IL‐17‐producing cells include γδ T cells, natural killer cells, group 3 innate lymphoid cells, and T helper type 17 (Th17) cells. There have been recent advances in our understanding of these cell populations in the lung as well as emerging data on how these cells are regulated in the lung. Moreover, Th17 cells may be a key component of tissue‐resident memory cells that may be acquired over time or elicited by mucosal immunization that provides the host with enhanced immunity against certain pathogens.
NMR study on reaction processes from aluminum chloride hydroxides to alpha alumina powders
Authors: Nýblová Daniela , Senna Mamoru , Düvel Andre , Heitjans Paul , Billik Peter , Filo Juraj , Šepelák Vladimír 
Published: September 2018

AbstractStarting from gelatinous aluminum chloride hydroxide, the transformation process toward α‐Al2O3 was examined using 27Al NMR, both in the liquid and solid states, as a main analytical tool. By increasing the hydrolysis ratio (h, defined as [OH−]/[Al3+]) of the starting aqueous precursor up to h = 2.5, the transition temperature to the final product, α‐Al2O3, decreased to as low as 500°C. In this case, the structural change from amorphous alumina to α‐Al2O3 took place without intermediate transition Al2O3 phases. Examining the process of networking during the transition from aqueous sol–through the state of xerogel–to final anhydrous oxide by nuclear magnetic resonance (NMR) revealed the presence of highly polymeric species mainly ascribed to δ‐[Al2O8Al28(OH)56(H2O)24]18+ (δ‐Al30). δ‐Al30 species were found in the solution phase and became predominant after drying. We conclude that the lower temperature synthesis of α‐Al2O3 became possible due to preformation of polymerized AlO6 construction units in the precursor, reducing the energy barrier for the nucleation of the final α‐Al2O3 phase.
The comprehensive in vitro evaluation of eight different calcium phosphates: Significant parameters for cell behavior
Authors: Šupová Monika , Suchý Tomáš , Sucharda Zbyněk , Filová Elena , der Kinderen Job N. L. M. , Steinerová Marie , Bačáková Lucie , Martynková Gražyna Simha 
Published: September 2018

AbstractEight different calcium phosphate nanoparticles, namely bovine bone bioapatite calcined at 500, 600, and 700°C, Mg‐doped brushite, fluorinated calcium phosphate, Ca‐deficient hydroxyapatite, hydroxyapatite, and tricalcium phosphate, were characterized employing physico‐chemical methods. Their cytocompatibility was evaluated under human osteoblast‐like cell line MG‐63 culture conditions in elution media and via the direct interaction of cells with calcium phosphate nanoparticles. The main objective was to determine the correlation of the cell indices with the differently determined physical and chemical parameters of the calcium phosphates. Chemical composition, which contributes toward pH changes, and the calcium ion concentration in the medium appear to make up particularly significant factors; moreover, it was proved that the number of material types represents a further important aspect. In the case of a large number of material types, almost no correlation was determined between the analyzed parameters; however, in the case of a small number of apatite types, several positive correlations were found. It can be concluded that it is not possible to identify any monitored parameters that had a major impact on cell behavior or, at least, such an effect which can be generalized. It appears more likely that cell behavior is affected by the interplay of various parameters.
Risk factors for catheter‐associated urinary tract infection among hospitalized patients: A systematic review and meta‐analysis of observational studies
Authors: Li Fei , Song Meixuan , Xu Linxia , Deng Bo , Zhu Shiqin , Li Xianrong 
Published: September 2018

AbstractAimsThe study aimed to identify the risk factors for catheter‐associated urinary tract infection among hospitalized patients. We also tried to explore its potential effect on patient outcomes if possible.BackgroundCatheter‐associated urinary tract infection accounts for a large proportion of healthcare‐associated infections and remains a considerable threat to patient safety worldwide.DesignA systematic review and meta‐analysis of observational studies.Data sourcesWe conducted an electronic search in PubMed, EMBASE, Web of Science, and the Cochrane Database of Systematic Reviews for studies published between January 2008–January 2018.Review methodsTwo reviewers searched the articles and extracted the data independently. The quality of the studies was assessed with the Newcastle‐Ottawa Scale. RevMan 5.3 was used to perform the meta‐analysis.ResultsTen studies involving a total of 8785 participants with or without catheter‐associated urinary tract infection were included. The average incidence of catheter‐associated urinary tract infection was 13.79 per 1000 catheter days, with a prevalence rate of 9.33%. The meta‐analysis demonstrated that patients at high risk for catheter‐associated urinary tract infection were female, had a prolonged duration of catheterization, had diabetes, had previous catheterization, and had longer hospital and ICU stays. Additionally, catheter‐associated urinary tract infection was also accompanied by an increase in mortality.ConclusionsHealthcare staff should focus on the identified risk factors for catheter‐associated urinary tract infection. Further research is needed to investigate the microbial isolates and focus on the intervention strategies of catheter‐associated urinary tract infection, so as to reduce its incidence and related mortality.
Integrating hypertension services at an HIV clinic in Port‐au‐Prince, Haiti: A report from the field
Authors: Walsh Kathleen F. , Lee Myung Hee , Martelly Shoria , Pierre Marie Melissa , Joseph Junon , Gustin Myrlene , Peck Robert N. , Fitzgerald Daniel W. , Pape Jean William , McNairy Margaret 
Published: September 2018

SummaryHIV‐positive adults with hypertension have increased risk of mortality but HIV clinics often do not provide hypertension care. The authors integrated hypertension management into existing HIV services at a large clinic in Haiti. Of 1729 documented HIV‐positive adults presenting for care at the GHESKIO HIV clinic between March and July 2016, 551 screened positive for hypertension, with systolic blood pressure ≥140 mmHg and/or diastolic blood pressure ≥90 mmHg. A convenience sample of 100 patients from this group received integrated hypertension and HIV care for 6 months. At time of identification, patients were screened for proteinuria and initiated on antihypertensive medication. Hypertension and HIV visits coincided; medications were free. Outcomes were retention in care and change in blood pressure over 6 months. Average blood pressure over 6 months was described using linear mixed‐effects model. Of 100 HIV‐positive adults with hypertension referred for integrated care, three were ineligible due to comorbidities. Among 97 participants, 82% (N = 80) remained in care at 6 months from time of positive hypertension identification. 96% (N = 93) were on antiretroviral therapy with median CD4+ count of 442 cells/µL (IQR 257‐640). Estimated average blood pressure over 6 months decreased from systolic 160 mmHg (CI 156, 165) to 146 mmHg (CI 141, 150), P‐value <0.0001, and diastolic 105 mmHg (CI 102, 108) to 93 mmHg (CI 89, 96), P‐value <0.0001. HIV and hypertension management were successfully integrated at a HIV clinic in Haiti. Integrated management is essential to combat the growing burden of cardiovascular disease among HIV‐positive adults.
Social Semantic Web Framework for Industrial Synergies Initiation
Authors: Ghali Mohamed Raouf , Frayret Jean‐Marc 
Published: September 2018

SummaryIndustrial synergies join two or more organizations that initially functioned as independent economic actors—that may originate from different sectors—together in order to share resources and exchange by‐products for mutual environmental, financial, and social benefits for its participants. Industrial symbioses (ISs) are networks of industrial synergies that can be initiated and created over time in various manners. In practice, the initiation of an industrial synergy, and particularly the identification of by‐product compatibilities, relies on direct or facilitated knowledge and information sharing, which is essential for discovering industrial synergy opportunities. Beyond its potential contribution to facilitate knowledge and information sharing among organizations, the Social Semantic Web (SSW) also has the potential to facilitate the initiation of industrial synergy by systematically and automatically identifying and recommending by‐products exchange compatibilities to potential partners. This framework exploits the ability of the sematic web to enable the search for analogies between potential partners within a region or district and existing industrial synergies around the world. This paper proposes the Social Semantic Web for Industrial Synergies Initiation (SSWISI) framework for the initiation of industrial synergies, which is based on the Social Semantic Web. The framework proposed in this paper adopts the concept of Linked Open Data (LOD), which enables the sharing and exchanging of information with external systems. This feature distinguishes the proposed framework from the existing approaches in its initiation of industrial synergies.
Chinese primiparous women's experience of the traditional postnatal practice of “Doing the month”: A descriptive method study
Authors: Zheng Xujuan , Watts Kim , Morrell Jane 
Published: September 2018

AbstractAim“Doing the month” has been a traditionally postnatal practice that women follow for one full month after giving birth. The aim of this study was to explore Chinese primiparous women's experience of “Doing the month” and why Chinese women felt satisfied or dissatisfied with the experience.MethodsThis was a descriptive survey using open and closed questions. In total, 420 Chinese primiparous women were recruited in obstetric wards at three hospitals in Xiamen City, China. Baseline questionnaires were distributed to the participants face‐to‐face by the researcher on the postnatal ward at 3 days’ postnatally. Follow‐up questionnaires of “Doing the month” were sent via email by the researcher to the participants at 6 weeks’ postnatally and were returned by the participants via email. The quantitative data were analyzed with SPSS and the qualitative data were analyzed by using a thematic text analysis.ResultsMost of the women thought that “Doing the month” after childbirth was necessary. Some women felt satisfied with “Doing the month” because their family helped them to have a good rest, they felt a sense of achievement when taking care of their baby, and that having an appreciative attitude helped them to get along with the older generations. In contrast, some women felt dissatisfied with “Doing the month” because of being tired of following taboos, having conflicts with their mother‐in‐law, the lack of family help and care, and undue expectations of “Doing the month.”ConclusionsIn order to improve postnatal care for Chinese primiparous women, health professionals could be more aware of how health care needs to be customized to fit the special tradition of “Doing the month.”
High‐affinity heterotetramer formation between the large myelin‐associated glycoprotein and the dynein light chainDYNLL1
Authors: Myllykoski Matti , Eichel Maria A. , Jung Ramona B. , Kelm Sørge , Werner Hauke B. , Kursula Petri 
Published: September 2018

AbstractThe close association of myelinated axons and their myelin sheaths involves numerous intercellular molecular interactions. For example, myelin‐associated glycoprotein (MAG) mediates myelin‐to‐axon adhesion and signallingviamolecules on the axonal surface. However, knowledge about intracellular binding partners of myelin proteins, includingMAG, has remained limited. The two splice isoforms ofMAG, S‐ and L‐MAG, display distinct cytoplasmic domains and spatiotemporal expression profiles. We used yeast two‐hybrid screening to identify interaction partners of L‐MAGand found the dynein light chainDYNLL1 (also termed dynein light chain 8).DYNLL1 homodimers are known to facilitate dimerization of target proteins. L‐MAGandDYNLL1 associate with high affinity, as confirmed with recombinant proteinsin vitro. Structural analyses of the purified complex indicate that theDYNLL1‐binding segment is localized close to the L‐MAGC terminus, next to the Fyn kinase Tyr phosphorylation site. The crystal structure of the complex betweenDYNLL1 and its binding segment on L‐MAGshows 2 : 2 binding in a parallel arrangement, indicating a heterotetrameric complex. The homology between L‐MAGand previously characterizedDYNLL1‐ligands is limited, and some details of binding site interactions are unique for L‐MAG. The structure of the complex between the entire L‐MAGcytoplasmic domain andDYNLL1, as well as that of the extracellular domain ofMAG, were modelled based on small‐angle X‐ray scattering data, allowing structural insights into L‐MAGinteractions on both membrane surfaces. Our data imply thatDYNLL1 dimerizes L‐MAG, but not S‐MAG, through the formation of a specific 2 : 2 heterotetramer. This arrangement is likely to affect, in an isoform‐specific manner, the functions ofMAGin adhesion and myelin‐to‐axon signalling.Open science badgesThis article has received a badge for *Open Materials* because it provided all relevant information to reproduce the study in the manuscript. The complete Open Science Disclosure form for this article can be found at the end of the article. More information about the Open Practices badges can be found athttps://cos.io/our-services/open-science-badges/.imageRead the Editorial Highlight for this article on page 712.
Prevalence and predictors of sexual function in midlife partnered Chinese women assessed by two simple indicators: Sexual frequency and sexual desire
Authors: Zhou Yang , Li Changbin , Jin Feng , Shao Hongfang , Teng Yincheng , Tao Minfang 
Published: September 2018

AbstractAimTo investigate the prevalence and predictors of sexual frequency, sexual desire in midlife partnered Chinese women.MethodsSexual frequency, sexual desire over the past 3 months, menopausal symptoms and other socioeconomic information were assessed for women aged 40–65 years in the Shanghai Sixth People's Hospital.ResultsAmong 3485 eligible partnered participants, the prevalence of low sexual frequency (less than once per week) and low sexual desire (less than 5 scores) were 72.74% (95% confidence interval (CI) = 71.16%–74.23%) and 71.79% (95% CI = 70.30–73.17%), respectively. Multivariable logistic regression analysis revealed that age (odds ratio (OR) = 1.20, 95% CI = 1.17–1.23), more educated (>15 years) (compared with<10 years, OR = 0.62, 95% CI = 0.48–0.82), perimenopause, postmenopause (compared with premenopause, OR = 1.48, 95% CI = 1.02–2.15, OR = 2.76, 95% CI = 1.80–4.23), sleep disorder (OR = 1.24, 95% CI = 1.02–1.50), unemployment (OR = 2.05, 95% CI = 1.45–2.92) were independently associated with low sexual frequency, while multiple linear regression revealed that age β = –0.126, 95% CI = –0.139––0.114), unemployment (β = –0.792, 95% CI = –0.954 to –0.629),chronic diseases (compared with no disease, single disease (β = –0.200, 95% CI = –0.020 to –0.077, multiple diseases (β = –0.792, 95% CI = –0.859 to –0.372), body mass index (β = –0.615, 95% CI = –0.859 to –0.372), postmenopause (β = –0.915, 95% CI = –1.143 to –0.759) were independent indicators for low sexual desire after adjusting for confounders.ConclusionLow sexual frequency and low sexual desire were quite prevalent in midlife Chinese partnered women. Some factors, such as sleep disorder, obesity are modifiable or can be prevented or treated with safe and effective therapies.