bluuebunny/crossref_metadata_2025_split huggingface dataset:
Petrological, petrofabric, and oxygen isotopic study of five ungrouped meteorites related to brachinites
Authors: Hasegawa Hikari , Mikouchi Takashi , Yamaguchi Akira , Yasutake Masahiro , Greenwood Richard C. , Franchi Ian A. 
Published: February 2019

AbstractNorthwest Africa (NWA) 6112, Miller Range (MIL) 090206 (plus its pairs: MIL 090340 and MIL 090405), and Divnoe are olivine‐rich ungrouped achondrites. We investigated and compared their petrography, mineralogy, and olivine fabrics. We additionally measured the oxygen isotopic compositions of NWA 6112. They show similar petrography, mineralogy, and oxygen isotopic compositions and we concluded that these five meteorites are brachinite clan meteorites. We found that NWA 6112 and Divnoe had a c axis concentration pattern of olivine fabrics using electron backscattered diffraction (EBSD). NWA 6112 and Divnoe are suggested to have been exposed to magmatic melt flows during their crystallization on their parent body. On the other hand, the three MIL meteorites have b axis concentration patterns of olivine fabrics. This indicates that the three MIL meteorites may be cumulates where compaction of olivine grains was dominant. Alternatively, they formed as residues and were exposed to olivine compaction. The presence of two different olivine fabric patterns implies that the parent body(s) of brachinite clan meteorites experienced diverse igneous processes.
Amelioration of nitrate uptake under salt stress by ectomycorrhiza with and without a Hartig net
Authors: Sa Gang , Yao Jun , Deng Chen , Liu Jian , Zhang Yinan , Zhu Zhimei , Zhang Yuhong , Ma Xujun , Zhao Rui , Lin Shanzhi , Lu Cunfu , Polle Andrea , Chen Shaoliang 
Published: February 2019

Summary

Salt stress is an important environmental cue impeding poplar nitrogen nutrition. Here, we characterized the impact of salinity on proton‐driven nitrate fluxes in ectomycorrhizal roots and the importance of a Hartig net for nitrate uptake.

We employed two Paxillus involutus strains for root colonization: MAJ, which forms typical ectomycorrhizal structures (mantle and Hartig net), and NAU, colonizing roots with a thin, loose hyphal sheath. Fungus‐colonized and noncolonized Populus × canescens were exposed to sodium chloride and used to measure root surface pH, nitrate (NO3−) flux and transcription of NO3− transporters (NRTs; PcNRT1.1, ‐1.2, ‐2.1), and plasmalemma proton ATPases (HAs; PcHA4, ‐8, ‐11).

Paxillus colonization enhanced root NO3− uptake, decreased surface pH, and stimulated NRTs and HA4 of the host regardless the presence or absence of a Hartig net. Under salt stress, noncolonized roots exhibited strong net NO3− efflux, whereas beneficial effects of fungal colonization on surface pH and HAs prevented NO3− loss. Inhibition of HAs abolished NO3− influx under all conditions.

We found that stimulation of HAs was crucial for the beneficial influence of ectomycorrhiza on NO3− uptake, whereas the presence of a Hartig net was not required for improved NO3− translocation. Mycorrhizas may contribute to host adaptation to salt‐affected environments by keeping up NO3− nutrition.
Continuous Bilateral Erector of Spine Plane Block at T8 for Extensive Lumbar Spine Fusion Surgery: Case Report
Authors: Almeida Carlos Rodrigues , Oliveira Ana Raquel , Cunha Pedro 
Published: February 2019

AbstractIntroductionSupplementary strategies, in combination with conventional analgesia, for pain control after lumbar fusion surgery remain limited.Case DescriptionHere, we describe a 79‐year‐old woman who experienced pain (10/10 on a numeric rating scale) on postoperative day 1 after undergoing L2 to S1 spine fusion. Erector spinae plane (ESP) blocks were performed at T8 and, after a bolus of ropivacaine 0.2% (20 mL) per side, perineural catheters were placed bilaterally. Continuous infusion (5 mL/h) of ropivacaine 0.2% per side was maintained for 48 hours. During this period, 2 boluses (15 mL) per day of ropivacaine 0.2% were administered bilaterally to maintain optimal analgesia.DiscussionBilateral ESP catheterizations at T8, placed remotely from the surgical site, may be considered for patients undergoing extensive spinal fusion procedures, because they contribute to significant analgesic improvement, without significant motor block; the effect of the block remains mostly in the posterior rami of spinal nerves and in the posterior bony elements of the vertebrae. The risk for hematoma or bacterial colonization related to catheter placement at T8 level using epidural or ESP techniques is low; nevertheless, a delay in the diagnosis of postoperative epidural hematoma or abscess directly related to the surgical intervention is a potential concern in spine fusion surgery. However, the action of an ESP block is primarily in the posterior rami of the spinal nerves, which makes an eventual neuraxial compression less likely to be masked by an ESP block compared with an epidural block, because an ESP hematoma or infection will not directly impinge on the spinal cord.Lay SummaryA 79‐year‐old woman experienced excruciating pain on post‐operative day 1 after undergoing L2 to S1 spine fusion. Bilateral continuous erector spinae plane (ESP) blocks were performed at T8 and, after a bolus of ropivacaine 0.2% (20 mL) per side, a continuous infusion (5 mL/hour) of ropivacaine 0.2% per side was maintained for 48 hours, which provided effective analgesia. During this period, two boluses (15 mL) per day of ropivacaine 0.2% were administered bilaterally to maintain optimal analgesia. ESP catheterizations at T8, placed remotely from surgical site, may be considered in extensive lumbar spinal fusion cases.
Priming xylem for stress recovery depends on coordinated activity of sugar metabolic pathways and changes in xylem sap pH
Authors: Pagliarani Chiara , Casolo Valentino , Ashofteh Beiragi Maryam , Cavalletto Silvia , Siciliano Ilenia , Schubert Andrea , Gullino Maria Lodovica , Zwieniecki Maciej A. , Secchi Francesca 
Published: February 2019

AbstractSome plant species are capable of significant reduction of xylem embolism during recovery from drought despite stem water potential remains negative. However, the functional biology underlying this process is elusive. We subjected poplar trees to drought stress followed by a period of recovery. Water potential, hydraulic conductivity, gas exchange, xylem sap pH, and carbohydrate content in sap and woody stems were monitored in combination with an analysis of carbohydrate metabolism, enzyme activity, and expression of genes involved in sugar metabolic and transport pathways. Drought resulted in an alteration of differential partitioning between starch and soluble sugars. Upon stress, an increase in the starch degradation rate and the overexpression of sugar symporter genes promoted the efflux of disaccharides (mostly maltose and sucrose) to the apoplast. In turn, the efflux activity of the sugar‐proton cotransporters caused a drop in xylem pH. The newly acidic environment induced the activity of apoplastic invertases leading to the accumulation of monosaccharides in the apoplast, thus providing the main osmoticum necessary for recovery. During drought and recovery, a complex network of coordinated molecular and biochemical signals was activated at the interface between xylem and parenchyma cells that appeared to prime the xylem for hydraulic recovery.
Root volatiles in plant–plant interactions II: Root volatiles alter root chemistry and plant–herbivore interactions of neighbouring plants
Authors: Huang Wei , Gfeller Valentin , Erb Matthias 
Published: February 2019

AbstractVolatile organic compounds (VOCs) emitted by plant roots can influence the germination and growth of neighbouring plants. However, little is known about the effects of root VOCs on plant–herbivore interactions of neighbouring plants. The spotted knapweed (Centaurea stoebe) constitutively releases high amounts of sesquiterpenes into the rhizosphere. Here, we examine the impact of C. stoebe root VOCs on the primary and secondary metabolites of sympatric Taraxacum officinale plants and the resulting plant‐mediated effects on a generalist root herbivore, the white grub Melolontha melolontha. We show that exposure of T. officinale to C.stoebe root VOCs does not affect the accumulation of defensive secondary metabolites but modulates carbohydrate and total protein levels in T. officinale roots. Furthermore, VOC exposure increases M. melolontha growth on T. officinale plants. Exposure of T. officinale to a major C. stoebe root VOC, the sesquiterpene (E)‐β‐caryophyllene, partially mimics the effect of the full root VOC blend on M. melolontha growth. Thus, releasing root VOCs can modify plant–herbivore interactions of neighbouring plants. The release of VOCs to increase the susceptibility of other plants may be a form of plant offense.
Perceived barriers to medication adherence remain stable following solid organ transplantation
Authors: Danziger‐Isakov Lara , Frazier Thomas W. , Worley Sarah , Williams Nikki , Shellmer Diana , Dharnidharka Vikas R. , Gupta Nitika A. , Ikle David , Shemesh Eyal , Sweet Stuart C. ,   the CTOTC‐05 Consortium
Published: February 2019

AbstractPerceived barriers to adherence have previously been investigated in SOT to identify plausible intervention targets to improve adherence and transplant outcomes. Fifteen centers in CTOTC enrolled patients longitudinally. Patients >8 years completed Adolescent Scale(AMBS) at two visits at least 6 months apart in the first 17 months post‐transplant while their guardians completed PMBS. Differences over time for pre‐identified AMBS/PMBS factors were analyzed. Perceived barrier reporting impact on subsequent TAC levels was assessed. A total of 123 patients or their guardians completed PMBS or AMBS. Twenty‐six were 6‐11 years and 97 were ≥12. The final cohort consisted of kidney (66%), lung (19%), liver (8%), and heart (7%) recipients. Unadjusted analysis showed no statistically significant change in reported barriers from visit 1 (median 2.6 months, range 1.2‐3.7 post‐transplant) to visit 2 (median 12, range 8.9‐16.5). Of 102 patients with TAC levels, 74 had a single level reported at both visits. The factor of “Disease frustration” was identified through the PMBS/AMBS questions about fatigue around medication and disease. Each point increase in “disease frustration” at visit 1 on the AMBS/PMBS doubled the odds of a lower‐than‐threshold TAC level at visit 2. No clear change in overall level of perceived barriers to medication adherence in the first year post‐transplant was seen in pediatric SOT. However, disease frustration early post‐transplant was associated with a single subtherapeutic TAC levels at 12 months. A brief screening measure may allow for early self‐identification of risk.
Validation of a Stochastic Discrete Event Model Predicting Virus Concentration on Nurse Hands
Authors: Wilson Amanda M. , Reynolds Kelly A. , Verhougstraete Marc P. , Canales Robert A. 
Published: February 2019

AbstractUnderstanding healthcare viral disease transmission and the effect of infection control interventions will inform current and future infection control protocols. In this study, a model was developed to predict virus concentration on nurses’ hands using data from a bacteriophage tracer study conducted in Tucson, Arizona, in an urgent care facility. Surfaces were swabbed 2 hours, 3.5 hours, and 6 hours postseeding to measure virus spread over time. To estimate the full viral load that would have been present on hands without sampling, virus concentrations were summed across time points for 3.5‐ and 6‐hour measurements. A stochastic discrete event model was developed to predict virus concentrations on nurses’ hands, given a distribution of virus concentrations on surfaces and expected frequencies of hand‐to‐surface and orifice contacts and handwashing. Box plots and statistical hypothesis testing were used to compare the model‐predicted and experimentally measured virus concentrations on nurses’ hands. The model was validated with the experimental bacteriophage tracer data because the distribution for model‐predicted virus concentrations on hands captured all observed value ranges, and interquartile ranges for model and experimental values overlapped for all comparison time points. Wilcoxon rank sum tests showed no significant differences in distributions of model‐predicted and experimentally measured virus concentrations on hands. However, limitations in the tracer study indicate that more data are needed to instill more confidence in this validation. Next model development steps include addressing viral concentrations that would be found naturally in healthcare environments and measuring the risk reductions predicted for various infection control interventions.
PMIs: Reliable indicators for exports?
Authors: Hanslin Grossmann Sandra , Scheufele Rolf 
Published: February 2019

AbstractForeign economic activity is a major determinant of export developments. However, foreign GDP figures are published too late to be useful for short‐term forecasting. This paper presents a number of indicators based on the widely available PMI surveys that provide very early signals of foreign activity. Using MIDAS models we analyze the in‐ and out‐of‐sample performance of these and related indicators for two very trade‐exposed countries (Germany and Switzerland). We find that the monthly indicators based on foreign PMIs are strongly correlated with quarterly export growth. The forecast comparison shows that PMI‐based indicators perform very well relative to other benchmark models.
Working with parents to counteract bullying: A randomized controlled trial of an intervention to improve parent‐school cooperation
Authors: van Niejenhuis Coby , Huitsing Gijs , Veenstra René 
Published: February 2019

This study examined the effectiveness of an intervention aimed at improving parent‐school cooperation in counteracting bullying. Using a randomized controlled trial, data of teachers, parents of non‐victimized children, and children themselves were collected at 13 intervention and 14 control schools (grades 3–6, N at post‐assessment: teachers = 83, parents = 153, children = 2,510) at two time points (time lag about 6 months). Results showed positive effects of the intervention for some aspects of the primary outcomes: parents’ and teachers’ attitudes and efforts, whereas no effects were found of teachers’ or parents’ competences in counteracting bullying. No intervention effects were found for secondary outcomes: children's self‐reported bullying, victimization, well‐being, and self‐esteem. The findings indicate that, due to the intervention, teachers and parents were more aligned and able to cooperate, even within the short time of the intervention: one school year. This is the first essential step to systematically addressing parents’ role in tackling bullying; future research is needed to examine the long‐term effects of parent and school interventions in enhancing the effectiveness of anti‐bullying programs.
Developing a new device for continuously recording, in vivo, the excretion rate of sweat (perspiration) in humans
Authors: Caberlotto Elisa , Guillou Carole , Colomb Loic , Barla Charlie , Salah Samir , Vicic Marco , Revol‐Cavalier Frederic , Rat Venceslass , Filipe Sabine , Flament Frederic 
Published: February 2019

BackgroundSome methodologies used for evaluating sweat production and antiperspirants are of a stationary aspect, that is, most often performed under warm (38°C) but resting conditions in a rather short period of time. The aim is to develop an electronic sensor apt at continuously recording sweat excretion, in vivo, during physical exercises, exposure to differently heated environments, or any other stimuli that may provoke sweat excretion.Material and MethodsA sensor (20 cm2) is wrapped under a double‐layered textile pad. Fixed onto the armpits, these two arrays of electrodes are connected to electronic system through an analog multiplexer. A microcontroller is used to permanently record changes in the conductance between two electrodes during exposure of subjects to different sweat‐inducing conditions or to assess the efficacy of applied aluminum hydrochloride (ACH)‐based roll‐ons at two concentrations (5% and 15%).ResultsIn vitro calibration, using a NaCl 0.5% solution, allows changes in mV to be related with progressively increased volumes. In vivo, results show that casual physical exercise leads to sweat excretions much higher than in warm environment (37 or 45°C). Only, an exposure to a 50°C environment induced comparable sweat excretion. In this condition, sweat excretions were found similar in both armpits and both genders. Decreased sweat excretions were recorded following applications of ACH, with a dose effect.ConclusionDeveloping phases of this new approach indicate that usual method or guidelines used to determine sweat excretions in vivo do not reflect true energy expenditure processes. As a consequence, they probably over‐estimate the efficacy of antiperspirant agents or formulae.
Transcriptional signatures modulating shoot apical meristem morphometric and plant architectural traits enhance yield and productivity in chickpea
Authors: Narnoliya Laxmi , Basu Udita , Bajaj Deepak , Malik Naveen , Thakro Virevol , Daware Anurag , Sharma Akash , Tripathi Shailesh , Hegde Venkatraman S. , Upadhyaya Hari D. , Singh Ashok K. , Tyagi Akhilesh K. , Parida Swarup K. 
Published: February 2019

SummaryPlant height (PH) and plant width (PW), two of the major plant architectural traits determining the yield and productivity of a crop, are defined by diverse morphometric characteristics of the shoot apical meristem (SAM). The identification of potential molecular tags from a single gene that simultaneously modulates these plant/SAM architectural traits is therefore prerequisite to achieve enhanced yield and productivity in crop plants, including chickpea. Large‐scale multienvironment phenotyping of the association panel and mapping population have ascertained the efficacy of three vital SAM morphometric trait parameters, SAM width, SAM height and SAM area, as key indicators to unravel the genetic basis of the wide PW and PH trait variations observed in desi chickpea. This study integrated a genome‐wide association study (GWAS); quantitative trait locus (QTL)/fine‐mapping and map‐based cloning with molecular haplotyping; transcript profiling; and protein‐DNA interaction assays for the dissection of plant architectural traits in chickpea. These exertions delineated natural alleles and superior haplotypes from a CabHLH121 transcription factor (TF) gene within the major QTL governing PW, PH and SAM morphometric traits. A genome‐wide protein‐DNA interaction assay assured the direct binding of a known stem cell master regulator, CaWUS, to the WOX‐homeodomain TF binding sites of a CabHLH121 gene and its constituted haplotypes. The differential expression of CaWUS and transcriptional regulation of its target CabHLH121 gene/haplotypes were apparent, suggesting their collective role in altering SAM morphometric characteristics and plant architectural traits in the contrasting near isogenic lines (NILs). The NILs introgressed with a superior haplotype of a CabHLH121 exhibited optimal PW and desirable PH as well as enhanced yield and productivity without compromising any component of agronomic performance. These molecular signatures of the CabHLH121 TF gene have the potential to regulate both PW and PH traits through the modulation of proliferation, differentiation and maintenance of the meristematic stem cell population in the SAM; therefore, these signatures will be useful in the translational genomic study of chickpea genetic enhancement. The restructured cultivars with desirable PH (semidwarf) and PW will ensure maximal planting density in a specified cultivable field area, thereby enhancing the overall yield and productivity of chickpea. This can essentially facilitate the achievement of better remunerative outputs by farmers with rational land use, therefore ensuring global food security in the present scenario of an increasing population density and shrinking per capita land area.
Immediate hypersensitivity reaction to human serum albumin in a child undergoing plasmapheresis
Authors: Wang Kathleen Y. , Friedman David F. , DaVeiga Sigrid Payne 
Published: February 2019

BACKGROUNDHuman serum albumin (HSA) is a commonly used colloid for volume expansion and albumin replacement and during plasmapheresis. Colloids are an uncommon cause of anaphylaxis, and cases of hypersensitivity reactions to HSA are extremely rare.CASE REPORTA 10‐year‐old boy with chronic inflammatory demyelinating polyneuropathy was treated with plasmapheresis, with albumin as the replacement fluid. He developed a severe reaction characterized by respiratory, gastrointestinal, and cutaneous symptoms.RESULTSSkin testing to HSA was positive and resulted in objective systemic symptoms, suggesting an immediate hypersensitivity reaction to HSA.CONCLUSIONWhile colloids are an uncommon cause of immediate hypersensitivity reactions, they can lead to severe and potentially fatal reactions if not recognized and treated promptly.
Single Sample Face Recognition in the Last Decade: A Survey
Authors: Kumar Nitin , Garg Vaani 
Published: February 2019

Single sample face recognition (SSFR) is a challenging research problem in which only one face image per person is available for training. Moreover, the face image may have different pose, expression, illumination, occlusion etc. rendering this problem more complex. Several methods have been suggested by various researchers in literature to solve SSFR. Here, we provide a comprehensive review of the methods proposed in the last decade for solving SSFR problem and introduce a novel taxonomy for the same. We divide SSFR methods broadly into five categories viz. (i) feature based, (ii) virtual sample generation based, (iii) generic database based, (iv) Hybrid and (v) other methods. We have also briefly reviewed the face databases used for evaluating single sample face recognition methods. Furthermore, the performance of the methods has been analyzed in terms of classification accuracy as given in literature. At last, we also suggest some future direction to the researchers and practitioners working in this fascinating research area.
A miRNA Expression Signature in Breast Tumor Tissue Is Associated with Risk of Distant Metastasis
Authors: Rohan Thomas E. , Wang Tao , Weinmann Sheila , Wang Yihong , Lin Juan , Ginsberg Mindy , Loudig Olivier 
Published: February 2019

AbstractDysregulation of miRNA expression may influence breast cancer progression, and experimental evidence suggests that miRNA silencing might suppress breast cancer metastasis. However, the relationship between miRNA and metastasis must be confirmed before this approach can be applied in the clinic. To this end, we conducted a two-stage study in a cohort of 3,760 patients with breast cancer to first identify and then validate the association between miRNA expression and risk of distant metastasis. The first stage (discovery) entailed miRNA sequencing of 126 case–control pairs; qPCR was used to validate the findings in a separate set of 80 case–control pairs. The 13 miRNAs most differentially expressed between cases and controls were combined into an miRNA score that was significantly associated with risk of distant metastasis in a logistic regression model that also included clinical variables (tumor size and number of positive lymph nodes) (ORper unit increase in score = 1.30; 95% confidence interval, 1.03–1.66). The results of this study suggest that in women with invasive breast cancer, a miRNA score that incorporates both clinical variables and miRNA expression levels in breast tumor tissue is moderately predictive of risk of subsequent distant metastasis.Significance:A novel predictive scoring system for patients with breast cancer includes clinical variables and the expression levels of 13 miRNAs and may help to identify those at increased risk of distant metastasis.