bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of body weight, serum glucose level and oxidative stress parameters of diabetic rats administered phenolic aqueous leaf extract of Vitex doniana
Authors: Obasi Emmanuel , Iheanacho Kizito , Nwachukwu Ngwu , Agha Nc , Chikezie Paul Chidoka 
Published: September 2019

Background: The present study evaluated the effect of phenolic aqueous leaf extract of Vitex doniana on body weight, serum glucose and oxidative stress parameters in diabetes mellitus (DM) rats.
Methods: DM was induced in rats by intraperitoneal injection of 100 mg/kg alloxan monohydrate in phosphate buffered saline (PBS; pH = 7.4). A total of 36 adult male Wister albino rats were divided into 6 groups of 6 rats. The groups consist of normal untreated rats, untreated DM rats, DM rats treated with 500 mg/kg dimethylguanide (MetforminTM) and DM rats treated with 100, 200 and 400 mg/kg body weight of phenolic aqueous leaf extract of Vitex doniana. The rats were treated for 28 days. Serum glucose, malondialdehyde (MDA), glutathione (GSH) and ascorbic acid concentrations, and serum superoxide dismutase (SOD) and catalase (CAT) activities were measured using standard methods. The changes in body weight was also measured.
Results: The results showed a significant reduction (p < 0.05) in serum glucose and MDA concentration, whereas serum SOD, CAT activities, as well as GSH and ascorbic acid concentration were significantly elevated (p < 0.05) in treated DM groups in a dose dependent manner.
Conclusion: The results of the present study indicated that phenolic aqueous leaf extract of V. doniana promoted increased body weight, ameliorated DM and alleviated reduced antioxidant activities in alloxan-induced DM rats. Phenolic aqueous leaf extract of V. doniana could serve as a potential natural and safe remedy for the management of DM.
Pemberdayaan Organisasi Sosial Kepemudaan Karang Taruna Bina Swakarsa Kecamatan Solokan Jeruk Melalui Program Keagamaan
Authors: Sonya Endah Ratna , Wulan Elis Ratna 
Published: September 2019

Program pengabdian masyarakat mengenai pemberdayaan organisasi sosial kepemudaan karang taruna melalui program kegiatan keagamaan sangat penting untuk dilaksanakan, organisasi sosial kepemudaan Karang Taruna memiliki sebuah keunikan, yaitu solidaritas dan kepedulian terhadap masyarakatnya sangat tinggi, dimana jika ada sebuah permasalahan sosial, maka semua anggota dan pengurus Karang Taruna ini biasanya langsung turun, untuk bersama-sama menyelesaikan masalah tersebut hingga tuntas dengan jalan mediasi ataupun arbitrasi. Di samping itu diharapkan melalui program kegiatan keagamaan dapat membantu meningkatkan perilaku keagamaan remaja di organisasi sosial kepemudaan Karang Taruna Desa Panyadap. Secara khusus tahapan kegiatan pengabdian masyarakat berupa: Pengajian Al-Quran remaja dan pembelajaran tajwid, Pemutaran film dokumenter, diskusi keagamaan dan pembagian takjil gratis, Ceramah Keagamaan, Bakti sosial, festival “sasauran” dan bazar Ramadhan.
Pasar Tradisional Syariah : Dari Teori Ke Implementasi (Pendampingan Di Pasar Syari’ah Campaka Kabupaten Cianjur)
Authors: Sururie Ramdani Wahyu , Sobana Dadang Husen 
Published: September 2019

Di tengah persaingan seperti sekarang ini, eksistensi pasar tradisional seolah “hidup segan mati pun tak mau”. Stigma negatif, tempatnya becek, kumuh, kotor, semrawut, banyak copet, minim fasilitas hingga ke karakter pedagangnya yang tidak jujur, mengurangi timbangan dan sebagainya. Oleh karena itu tidak sedikit masyarakat tidak peduli dengan keberadaan pasar tradisional ini, hingga banyak dari konsumen beralih ke pasar modern, yang ramah, bersih, aman, nyaman dan seabreg keunggulan lain. Padahal sejatinya pasar tradisional ini adalah urat nadi perekonomian nyata di negeri yang mayoritas Muslim ini. Visi Kabupaten Cianjur, “Cianjur Lebih Maju dan Agamis”. aksentuasi pada gerakan Cianjur Agamis yang terimplementasikan dalam aktiftas perdagangan yaitu direalisasikan pendirian pasar tradisional syariah di Kecamatan Campaka yang disingkat Pasar Syariah Campaka (PSC). Tujuan pengabdian ini: pertama, mendampingi penyusunan naskah akademik mengenai konsep pasar syariah yang langsung diimple¬mentasikan di Pasar Tradisional Syari’ah di Kecamatan Campaka; Kedua, mendampingi para calon pengelola dan pedagang Pasar Rakyat Syari’ah Campaka hingga memahami hak dan kewajibannya sebagai pedagang di PSC. Ketiga Mendampingi Pemerintah Daerah cq. Dinas Koperasi UKM, Perdagangan dan Perindustrian Kabupaten Cianjur dalam mewujudkan Pasar Syariah Campaka sebagai destinasi wisata ekonomi syariah di Kabupaten Cianjur untuk menunjang wisata ungulan Cianjur situs megalitikum Gunung padang; Metode pengabdian dilakukan dengan metode bimbingan, asistensi, pengarahan, pelatihan dan kegiatan sejenis lainnya kepada stake holders pasar syari’ah Campaka guna meningkatkan kemampuan dan kepedulian mereka dalam memberikan layanan dan pengelolaan serta pembiasaan sesuai dengan etika bisnis, prinsip-prinsip dan karakteristik pasar syari’ah yang dikehendaki.Hasil kajian dan pengabdian memperlihatkan, bahwa subjek-subjek yang mesti ada dalam Pasar Syariah Campaka adalah, 1). Pengelola Pasar, 2) Pedagang; 3). Pembeli; 4) Distributor; 5) Dewan Pengawas Pasar Syari’ah Campaka (DPPSC); 6) Lembaga Keuangan Syari’ah Pendukung Pasar Syar’ah Campaka (LKS-PPSC); 7) Lembaga Penyelesaian Perselisihan Pelaku Pasar Syari’ah Campaka (LPPPPSC/LP4SC). Dengan kriteria-kriteria pasar adalah: Akad-akad (transaksi) mesti akad syari’ah dengan rukun dan syarat yang terpenuhi, Permodalan Pedagang mesti dari Lembaga keuangan berbasis syari’ah; Jenis dan Barang yang diperdagangkan harus halal; Alat Ukur / Timbangan tidak boleh dikurangi/curang dan harus akuntable; Harga di Pasar Syari’ah Campaka tidak mahal namun berkeadilan; Lingkungan yang bersih, aman dan nyaman (asri suasana islami); serta adanya reward & Funnisment bagi para pedagang di PS Campaka.
Pelatihan Instalasi Listrik Dan Sound System Untuk Menumbuhkan Jiwa Entrepreneurship Santri Di Pondok Pesantren Roudlotul 'Ulum Bandung Barat
Authors: Kamelia Lia , Ismail Nanang , Faroqi Adam , Mardiati Rina 
Published: September 2019

Pengabdian Kepada Masyarakat (PPM) merupakan suatu media untuk menjembatani dunia pendidikan dengan masyarakat, dimana Perguruan Tinggi dihadapkan pada masalah bagaimana agar warga masyarakat mampu menghadapi tantangan lebih jauh ke depan di era globalisasi dengan berwirasusaha, mengenal berbagai keterampilan, dan berbagai bentuk pendidikan di luar sistem persekolahan. Pondok Pesantren Salafiyah dan Da'wah Roudlotul 'Ulum yang sudah berjalan sejak tahun 2001 telah memiliki lahan seluas 2000 m2 dan telah berwujud dalam 1 masjid, 9 asrama santri, madrasah sebagai ruang mengaji dan lain sebagainya Jumlah total santri saat ini berjumlah 150 orang. Sejak pertama dibangun, instalasi listrik dilakukan secara bertahap dengan pengerjaan dilakukan oleh sumber daya manusia yang tidak memahami tentang masalah kelistrikan sehingga menyebabkan instalasi tidak sesuai dengan standar kelistrikan. Setelah dilakukannya kegiatan ini diharapkan sistem suara yang berkualitas yang digunakan di Pondok Pesantren Salafiyah dan Da'wah Roudlotul 'Ulum bisa mengoptimalkan kegiatan keagamaan di pondok pesantren tersebut juga bisa terbentuknya sebuah kelompok usaha perbaikan dan instalasi listrik khususnya sound system untuk menunjang perekonomian pesantren. Kegiatan dibagi dalam 3 tahap yaitu : persiapan; pelatihan dengan materi pengenalan tentang instalasi listrik , pengenalan sistem suara, perakitan amplifier, dan tahap akhir pendampingan. Diharapkan kedepan diperlukan tindak lanjuti oleh seluruh pihak yang terkait untuk meyediakan segala hal yang berkaitan dengan sarana dan prasarana yang dibutuhkan sebagai langkah awal untuk menumbuh kembangkan semangat jiwa wirausaha (entrepreneur) bagi para santri. Oleh karenanya perlu ditingkatkan kerjasama yang lebih erat dan terencana antara Perguruan Tinggi dan Pemerintah Daerah untuk menggali potensi-potensi yang ada di wilayah tersebut.
Optimalisasi Pengadaan Bank Sampah Berbasis Masyarakat Yang Bernilai Ekonomis
Authors: Octavia Vera , Fitri Yuda Septia 
Published: September 2019

Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan kepedulian masyarakat terhadap pemanfaatan sampah anorganik, bahkan lebih jauh menjadi kegiatan yang bernilai ekonomi tinggi. Khalayak sasaran dalam pengabdian ini berupa pilot project pada ibu-ibu rumah tangga anggota KWT Usaha Tani yang berada di RW 05 Dusun Sukamaju, Desa Mulyasari, Kecamatan Pataruman, Kota Banjar, Jawa Barat. Universitas Islam Sunan Gunungdjati Bandung memiliki komitmen yang kuat untuk terlibat dalam mengembangkan dan membangun berbagai potensi tersebut dengan cara berperan aktif untuk memberikan kesadaran dan keterampilan bagi masyarakat melalui pengelolaan sampah berwawasan lingkungan dalam rangka meningkatkan perekonomian keluarga. Pelaksanaan pengabdian berlangsung selama 4 bulan, meliputi kegiatan perencanaan, pelaksanaan dan evaluasi. Pelaksanaan pelatihan ini dimulai dari survei lapangan dan koordinasi dengan pihak desa serta dinas Lingkungan Hidup Kota Banjar, kemudian dilanjutkan dengan sosialisasi program dan pelaksanaan program. Target luaran berupa menbantu dan mengenalkan langkah-langkah yang ditempuh untuk mengoptimalisasi pengadaan bank sampah tercapai. Diharapkan peran pemerintah dan pergururan tinggi secara bersinergi dan profesional dapat membantu mengatasi permasalahan di masyarakat dan memberikan kontribusi luar biasa terhadap pembangunan ekonomi.
Frequency of risk factors for chronic noncommunicable diseases among physicians in Russian Federation on the model of Tomsk Region
Authors: Kobyakova O. S. , Kulikov E. S. , Deev I. A. , Almikeyeva A. A. , Pimenov I. D. , Starovoitova E. A. 
Published: September 2019

Aim. To determine the frequency and structure of risk factors (RF) for chronic noncommunicable diseases (CNCDs) among physicians in the Tomsk Region.Material and methods. The questionnaire was compiled based on the methodological guidelines “Monitoring of risk factors for chronic noncommunicable diseases in practical healthcare”. The questionnaire was provided in electronic format and posted on the site http://www. golosaonline.ru/medto.Results. Doctors of the Tomsk region revealed a high frequency of such RF for CNCDs as chronic as hypodynamia (45,7%), improper feeding (67,6%) and overweight (34,7%).Conclusion. The study showed that the frequency of RF for CNCDs in a Tomsk region was lower than the same one in general population. However, there is a need to develop practical guidelines for healthcare workers.
Echo-cardiographic parameters for atrial fibrillation in combination with acute coronary syndrome in real clinical practice according to register of acute coronary syndrome in the Krasnodar region
Authors: Tatarintseva Z. G. , Kosmacheva E. D. , Porhanov V. A. , Kruchinova S. V. 
Published: September 2019

Aim. To evaluate patients with acute coronary syndrome (ACS) in combination with atrial fibrillation (AF) according to the total register of ACS in the Krasnodar region of echocardiographic (EchoCG) parameters (left atrial dimension (LAD), left ventricular wall thickness (LVWT), left ventricle end-diastolic diameter (LVEDD), left ventricular ejection fraction (LVEF), pulmonary artery systolic pressure (PASP), as well as coronary substrate assessment according to coronary angiography (CAG) and determination of the relationship between the value of LVEF and the coronary substrate.Material and methods. From the register of the ACS in the Krasnodar region, patients were successively taken to the cardiology departments of Krasnodar regional clinical hospital № 1 for the period from November 20, 2015 to November 20, 2017 with a diagnosis of ACS, accompanied by one of the types of atrial fibrillation. This group of patients was designated as a group of ACS + AF and amounted to 119 patients. The comparison group was selected with the help of a random number generator from patients admitted to the hospital with ACS and intact sinus rhythm (SR) for the period of time from November 20, 2015 to November 20, 2017 (120). We analyzed the ECHO-CG parameters, the coronary substrate — according to the CAG.Results. When comparing the cohort of patients with ACS + AF with the cohort of patients with ACS + SR, we determined a significant (p<0,05) difference of LA size, LVEF and values of PASP. During comparing the presence of hemodynamically significant stenosis in the coronary arteries we noticed that in ACS + AF patients with LVEF <40% in significantly higher percentage of cases (p=0,0007) occurs significant hemodynamic stenosis of coronary arteries, in contrast to the group of patients with ACS + SR with LVEF <40%. In patients with EF >40% and ACS + SR we determined a significantly more frequent (p<0,001) stenosis.Conclusion. The results of the analysis are important for understanding the distinguishing characteristics of patients with ACS that occur on the background of AF, which is important for correct prediction of the course of the disease. The maintenance of the ACS register will provide information on the real clinical course of the disease, as well as improve the effectiveness of treatment in real clinical practice.
What is this Article about? Extreme Summarization with Topic-aware Convolutional Neural Networks
Authors: Narayan Shashi , Cohen Shay B. , Lapata Mirella 
Published: September 2019

We introduce "extreme summarization," a new single-document summarization task which aims at creating a short, one-sentence news summary answering the question "What is the article about?". We argue that extreme summarization, by nature, is not amenable to extractive strategies and requires an abstractive modeling approach. In the hope of driving research on this task further: (a) we collect a real-world, large scale dataset by harvesting online articles from the British Broadcasting Corporation (BBC); and (b) propose a novel abstractive model which is conditioned on the article's topics and based entirely on convolutional neural networks. We demonstrate experimentally that this architecture captures long-range dependencies in a document and recognizes pertinent content, outperforming an oracle extractive system and state-of-the-art abstractive approaches when evaluated automatically and by humans on the extreme summarization dataset.
Declining the Big East: A Case Study of the College of the Holy Cross
Authors: Weaver Anthony G 
Published: September 2019

Abstract The case study examines Holy Cross’ decision not to join the Big East Conference in 1979. Specifically, the case analyzes the commitment to a marketing strategy to de-emphasize athletics at a time when many institutions were using the growth of television to help market their university brand. The study also highlights the impact the decision has had on the institution and the athletic department since 1979. Data were gathered by interviewing two former administrators with over 50 years of experience at Holy Cross, and reviewing archival data and documents including administrators’ correspondence and letters, newspaper articles, magazines and websites related to Holy Cross athletics. Themes are presented in a chronological format to show the sequence of each theme. Results indicated that although the Big East presented many opportunities, administrators valued the academic brand of the institution and refused to sacrifice that brand in the pursuit of big-time athletics.
Diagnostic significance of hormonal, biochemical and echographic methods in postmenopausal women with endometrial cancer
Authors: Garashova M. A. , Alieva E. M. 
Published: September 2019

Aim: to evaluate the significance of hormonal, biochemical, and echographic methods in the diagnosis of endometrial cancer.Materials and methods. Fifty patients (aged 62.4 ± 1.0) with endometrial cancer of varying severity and 20 practically healthy postmenopausal women (aged 68.0 ± 0.7) were examined. All patients underwent hormonal, biochemical, and echographic examinations.Results. At the period of this study, 68 % of patients had stage I cancer, 30 % had stage II, and 2 % – stage III endometrial cancer. In the medical history of examined patients, the incidence of abortion was 46.8 %, the rate of childbirth – 70.0 %, the infertility rate – 14.9 % (n = 7). A statistically significant decrease in the luteinizing/follicle-stimulating hormone ratio (0.69 ± 0.09), an increase in the levels of prolactin (467.3 ± 35.1 ng/ml), dehydroepiandrosterone-sulfate (92.9 ± 14.4 pg/ml), estrone (101.60 ± 6.29 ng/ml), progesterone (1.90 ± 0.52 ng/ml), as well as a decrease in estradiol (17.4 ± 3.4 pg/ml) and total testosterone (0.50 ± 0.02 ng/ml) in comparison with the practically healthy postmenopausal women (control group) were found. According to the echographic examination, a pathological increase in the endometrium thickness (24.9 ± 2.7 mm) was detected against the background of uterus and ovaries enlargement. The biochemical parameters in patients with endometrial cancer in the postmenopausal period were within the normal range.Conclusion. The risk of endometrial cancer is high in elderly women with an increased body mass index. Evaluating of their hormone levels is of diagnostic and prognostic importance in endometrial cancer. Transvaginal sonography is an accurate diagnostic method for assessing the tumor invasion into the myometrium of patients with endometrial cancer.
Antimicrobial peptides in pregnant women with TORCH infections
Authors: Narimanova G. V. , Shakhverdieva I. D. , Kerimova I. A. , Jafarova G. A. 
Published: September 2019

Introduction. Analysis for TORCH infections is ordered to simultaneously detect several common infections: Toxoplasmosis, Other infections (syphilis, hepatitis B, chickenpox, Epstein-Barr virus, parvovirus and some others), Rubella, Cytomegalovirus and Herpes simplex virus. Contracting a TORCH infection in pregnancy triggers the synthesis of immune factors including antimicrobial peptides (AMPs).Aim: to determine the levels of AMPs – lactoferrin, defensin, endotoxin, BPI (bactericidal/permeability-increasing protein) and hepcidin – in the blood serum of pregnant women with TORCH infections.Materials and methods. The main group included 40 pregnant women with TORCH infections; in 33 of those, pregnancy continued until full-term delivery, and 7 women had miscarriages at the end of the first trimester. The comparison group consisted of 29 pregnant women free of TORCH infections. Blood for AMP measurement was taken in all pregnant women in the first trimester and in women with an ongoing pregnancy also in the III trimester. The control group consisted of 19 healthy non-pregnant women. Serum AMP was determined by enzyme-linked immunosorbent assay (ELISA).Results. In pregnant women with TORCH infections, there was an increase in the serum levels of lactoferrin, defensin, hepcidin, BPI, and endotoxin; the increase was most pronounced in the first trimester of pregnancy. The decrease in AMP levels observed in the III trimester could be due to the antiviral treatment given to the patients in order to prevent the immunological rejection of the embryo and maintain the normal course of pregnancy.Conclusion. The increased level of AMPs reflects the enhanced activity of the immune system and represents one of the pathogenetic links of spontaneous abortion.
JAK2V617F-positive clonal hematopoiesis of indeterminate potential in pregnant women
Authors: Olkhovskiy I. A. , Garber J. G. , Gorbenko A. S. , Stolyar M. A. , Miller O. M. , Kostina E. S. , Komarovskiy Yu. Yu. , Potilitsina V. V. 
Published: September 2019

Aim: to assess the prevalence of V617F somatic mutation of the JAK2 gene in pregnant women.Materials and methods. This non-interventional study was performed in the framework of routine clinical practice and included 1532 samples of venous blood from pregnant women who applied for medical assistance at Krasnoyarsk Regional Clinical Center for Maternal and Child Welfare. We used blood samples left after all routine laboratory tests had been done. These leftovers were pooled in the way that ensured an equal ratio of nucleated cells. Each pool contained 7 separate blood samples. The unused samples that remained after the pooling were frozen and stored at –20°C until the end of entire testing procedure. The V617F JAK2 mutation was detected by the real-time allele-specific polymerase chain reaction test.Results. Among the examined pregnant women, 6 (0.4 %) were identified as carriers of V617F JAK2 mutation. Three women with this mutation suffered from infertility for 4, 5, and 10 years; two of them had repeated miscarriages in the first trimester of pregnancy. The 6 women – carriers of this mutations had no concomitant genetic polymorphisms typical of thrombophilia (factors FII, FV), and no abnormal coagulation characteristics. Analysis of their medical records showed that in the past, two of these women had gestational hypertension, one developed a clinical picture of preeclampsia, and another one (with the maximum presence of the mutant allele) had a history of acute lymphoblastic leukemia followed by stable remission.Conclusion. The routine laboratory detection of the V617F JAK2 mutation can facilitate timely identification of the increased risk of pregnancy pathology, as well as timely diagnosis of hematological cancer.
Vaginal biocenosis in pregnant women with recurrent bacterial vaginosis after treatment with recombinant human interferon alpha-2b
Authors: Podgornaya A. V. , Makhmutkhodzhaev A. Sh. 
Published: September 2019

Introduction.Preventing recurrent bacterial vaginosis (BV) during pregnancy is an important issue in current obstetrics.Aim:to assess the effect of recombinant human interferon alpha-2b on the incidence of recurrent BV during pregnancy and on the bacterial, cytokine, and antimicrobial components of the nonspecific vaginal immunity.Materials and methods.The study included 80 pregnant women with recurrent BV, 40 of whom (the main group) were treated with recombinant human interferon alpha-2b in the first half of pregnancy and after 30 weeks of pregnancy in addition to standard therapy (metronidazole or clindamycin). The other 40 women (control group) did not receive this interferon drug. Patients of the both groups were examined for the rate of BV recurrence and also tested for their vaginal bacteria and levels of β-defensin-2 (HBD-2), interleukin-1β (IL-1β), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), and interferon-γ (INF-γ) in the third trimester of pregnancy.Results.Treatment with recombinant human interferon alfa-2b led to a 3-fold reduction in the occurrence of repeated episodes of BV and an increase in the content of lactobacilli (7.24 ± 0.33 and 7.03 ± 0.40 in patients with interferon therapy and without it, respectively; p = 0.013) mainly due to Lactobacillus crispatus (7.14 ± 0.69 in women who received interferon alfa-2b, compared with 6.36 ± 0.95 in patients on standard therapy; p = 0.003) and a decrease in the number of some types of anaerobes. Also, the use of interferon alpha-2b in pregnant women with recurrent BV led to an increase in the content of IL-1β by 2.5 times, IL-6 by 3.5 times, IL-10 by 1.5 times, INF-γ by 2 times, and HBD-2 by 4 times.Conclusion.Treatment of recurrent BV during pregnancy with recombinant human interferon alfa-2b, aimed at boosting the nonspecific vaginal immunity helps reduce the incidence of recurrent BV.