bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALYZING THE STRATEGIC ALIGNMENT BETWEEN INFORMATION SYSTEM TECHNOLOGY AND BUSINESS PROCESS IN SMALL MEDIUM ENTERPRISE (SME) USING FRAMEWORK COBIT 4.1– A CASE STUDY IN UNIVERSAL TRADING, SURABAYA
Authors: Hartanti Benih 
Published: June 2019

This research was conducted in Universal Trading as one of SME that applies Information Technology as daily business process in order to analyze whether the use of Information Technology is alligned with the strategy formulation. Type of research is Descriptive Research with Qualitative technique by using direct observation and depth interview with all user of TI from leader to staff. In depicting a further detail description, Internal and External Matrixas well as COBIT Verse 4.1 were utilized in supporting so. From the position of Average as a result of IFE-EFE Matrix and the Score of COBIT 4.1 in primary process of Strategic Allingment is 2,95 could be concluded that only strategy of new market penetration could be alligned by the use of Information Technology as the company basic business process is limiting the strategy of new product development using only company’s internal source. Keyword: strategic allignment, information technology, COBIT 4.1
Cervical vertigo in severe cervical spondylosis: frequent or over- diagnosed?
Authors: Kadaňka Zdeněk , Kadaňka Zdeněk , Jura Rene , Bednarik Josef 
Published: June 2019

Abstract
Background
Cervical vertigo (CV) is a grossly over-diagnosed entity although, in all probability, it does not exist. The aim of this study was to test following hypothesis: that even in patients with one of the most severe forms of cervical spondylosis, degenerative cervical myelopathy (DCM), stimulation of the cervical proprioceptors does not provoke or increase vertigo
Methods
The study was performed in a cohort of 38 patients with DCM confirmed by clinical manifestation and MRI-detected degenerative cervical cord compression. The incidental presence of vertigo in these patients was investigated by means of a questionnaire and a clinical neurological examination. The cervical torsion test (to stimulate cervical proprioceptors), and ultrasound examinations of the extracerebral carotid and vertebral arteries (to exclude impaired blood circulation in the cervical region) were performed. All patients with vertigo underwent a diagnostic work-up designed to reveal its cause.

Results: Subjective symptoms of vertigo occurring in the six months previous to examination were reported by 18 patients (47%). None of these patients responded positively to the cervical torsion test, while highly probable explanations involving an etiology for vertigo other than from the cervical region were found in all patients suffering from it. No patient exhibited significant stenosis of the vertebral arteries.
Conclusions: There were no clear signs of CV in the cohort of patients with DCM. If patients with cervical spondylosis suffer from vertigo, its cause may, more easily be explained by common and treatable etiologies that do not lie in the cervical region.
Ten years of prevalence and clinical laboratory features of HCMV infected children in a hospital of Jiangsu Province
Authors: Shang Wenwen , Zhao Hong , Rong Guodong , Xu Ting , Wu Lei , Huang Peijun , Wang Fang , Zhang Jiexin 
Published: June 2019

Abstract
Background: Human cytomegalovirus (HCMV) is prevalent worldwide and causing lifelong infection. We conducted a retrospective study to determine the epidemiology and clinical laboratory characteristics of CMV infection in children in a hospital of Jiangsu Province.
Methods: Totally 2600 urine specimens of infants and children hospitalized in general pediatric from 2009 to 2018 were collected followed by CMV-DNA loads detection. Among them, clinical records and laboratory results of 971 infants aged 3-12 months were focused for further statistics analysis.
Results: Urine CMV-DNA load test was intensively ordered in 2011 (17.76%; 532/2996) for infants under 1 month but the rate continuously dropped ever since. In fact, infants under 1 month had the lowest detection sensitivity and children aged between 3 to 24 months had the highest positive rate. On the contrary, analysis of blood routine test showed that the absolute counts of peripheral leukocytes (P=0.008), monocytes (P=0.039), neutrophils (P<0.001) and platelets (P=0.006) were significantly decreased in CMV+ group compared with CMV- group. The percentages of neutrophils (NEUT%) were decreased (P<0.001) while the percentages of lymphocytes (LYM%) were increased (P<0.001) by CMV infection. Moreover, NLR (neutrophil to lymphocyte ratio) (P<0.01), MLR (monocyte to lymphocyte ratio) (P=0.017) and SII (systemic immune index) (P=0.002) were also decreased in CMV+ group. The hospitalization of cases in CMV+ group was significantly longer than that of the CMV- group (P=0.039), and the proportion of children with hospitalization stay longer than 2 weeks in CMV+ group was higher, with significant difference (P=0.006).
Conclusion: CMV survey has not drawn much attention in hospitalized infants and children, and the combined application of urine CMV detection and blood routine test should be benefit when assessing CMV infections.
Performance capacity of the health system workforce towards integrated leading-managing-and-governing practices in Ethiopia: with special reference to the application of factor analysis and ordinal logistic regression
Authors: Ambelie Yeshambel Agumas , Alene Getu Degu , Gebrekiros Damen Hailemariam 
Published: June 2019

Abstract
Background

Observing over-led and under-managed, over-managed and under-governed, and even out of these health organizations remains a common phenomenon in low and middle-income countries including Ethiopia. To balance these discrepancies, leadership and governance is regarded as the locus of all other critical health system building blocks. Thus, the current study looks at the performance capacity of the health system workforce towards integrated leading-managing-and-governing practices and its predictors in Ethiopia.

Methods

Eight-hundred-thirteen health system workforce were participated in this study. These were selected from 32 health care organizations located in northwest Ethiopia. Data were collected using a multi-item questionnaire. These data were fitted to factor analysis and ordinal logistic regression models. Factor analysis was used to develop scientifically reliable and empirically scalable measurement model. Once this model was tested for reliability and validity, the performance capacity of the health system workforce towards integrated leading-managing-and-governing practices (the outcome variable) was computed and labeled. Finally, ordinal logistic regression was conducted to model relationships between the outcome variable and its predictors using probability value and odds ratio.

Results

From 813 participants who rated the questionnaire, 396 (48.7%) and 582 (71.6%) were females and service owners respectively. Using these ratings, four factors were extracted. These factors together with items rated and error variances provided a four-factor measurement model. This model had estimates above .5, composite reliability above .7 and average variance extracted above .5. Using items in this model, the outcome variable was labeled as low (41.3%), moderate (42.7%), high (13.5%) and very high (2.5%). Sex and responsibility were among significantly associated predictors.

Conclusions

Empowering the health system workforce towards integrated leading-managing-and-governing practices using scientifically reliable and empirically scalable model is important, particularly in resource-limited settings. The policies and strategies developed in this regard should give due attention to females and service owners. The current results could provide foundations for training and future research.

Trial registration

The current study was part of a PhD dissertation research, which has been registered at clinical trials.gov since 9 July 2018 with identifiers: NCT03639961.
Networks and Institutionalization: A Neo-structural Approach
Authors: Lazega Emmanuel 
Published: June 2019

Abstract
This paper is the text prepared for the keynote address of the EUSN 2017 conference in Mainz, Germany. A short presentation of concepts reflects in part the foundations of neo-structural sociology (NSS) and its use of social and organisational network analyses, combined with other methodologies, to better understand the roles of structure and culture in individual and collective agency. The presentation shows how NSS accounts for institutional change by focusing on the importance of combined relational infrastructures and rhetorics. Specific characteristics of institutional entrepreneurs who punch above their weight in institutionalization processes are introduced for that purpose, particularly the importance of multi-status oligarchs, status heterogeneity, high-status inconsistencies, collegial oligarchies, conflicts of interests and rhetorics of relative/false sacrifice. Two empirical examples illustrate this approach. The first case focuses on a network study of the Commercial Court of Paris, a 450-year-old judicial institution. The second case focuses on a network study of a field-configuring event (the so-called Venice Forum) lobbying for the emergence of a new European jurisdiction, the Unified Patent Court, and its attempt to create a common intellectual property regime for the continent. For sociologists, both examples involve “studying up”: they are cases of public/private joint regulation of markets bringing together these ingredients of institutionalization. The conclusion suggests future lines of research that NSS opens for the study of institutionalization, in particular using the dynamics of multi-level networks. One of the main issues raised by this approach is its contribution to the study of democratic deficits in a period of intense institutional change in Europe.
The Boston Special Youth Project Affiliation Dataset
Authors: Young Jacob T.N. , Decker Scott H. , Sweeten Gary 
Published: June 2019

Abstract
The Boston Special Youth Project (SYP) Affiliation dataset is a large, bipartite network representing interactions among 166 gang members from seven gangs for nearly three years. The project was conducted from June 1954 to May 1957 and represents one of the most elaborate gang intervention programs ever conducted. The SYP was a “detached-worker program,” where an adult (typically a graduate student from one of the surrounding universities) was assigned to an area (local parks, housing projects) to establish and maintain contact with and attempt to change the behaviors of the gangs. These workers collected detailed field notes (“contact cards”) documenting the activities of study gang members. However, the social network data collected on the contact cards were never analyzed by SYP staff. After the death of the project leader, Walter Miller, in 2004, the materials from the project became available to a team of researchers (faculty, graduate, and undergraduate students) in the School of Criminology and Criminal Justice at Arizona State University. These researchers electronically scanned and digitized the contact cards, and began the process of creating a network from the cards. From these cards, a bipartite network was created where 166 individuals (i.e. gang members) were connected to 33,653 events (i.e. contact cards).
Technology Transfer and the Promotion of Technical Skills from Japan to Southeast Asia: Case Study of Vietnam
Authors: Nguyen Quynh Huong 
Published: June 2019

In this era of globalization, technology transfer is widely regarded as a significant vehicle by which developing countries can both acquire technologies and develop human resources. Also, the skills level of employees has been identified in playing a critical role in making technology transfer effective. Japan is one of the largest investors in Vietnam. Japanese foreign direct investment (FDI) projects that are large in terms of investment capital and concentrate in high technology industries, are predicted to continue to increase and they offer the promise of new employment and technology transfer opportunities for Vietnam and its people. However, the lack of a skilled labor force in Vietnam, especially in the manufacturing industry, has currently impeded the transfer of technologies from Japan to Vietnam. Human resource development in general and technical skill promotion in particular are critical requirements for Vietnam to take advantage of technology transfer.This paper attempts to evaluate the current situation of technical skill levels of employees in the Vietnamese manufacturing industry, as well as technology transfer from Japan to Vietnam through Japanese FDI manufacturing firms. In addition, this paper introduces the current policies and strategies of the Vietnam government in relation to technology transfer issues. It is suggested in this paper that bridging the huge gap between Japanese technical standards and the Vietnamese workforce’s technical skills definitely requires the crucial role of the Vietnamese government. The author then provides some recommendations for the government to adopt in order to upgrade technical skill levels to effectively adopt and utilize technologies transferred from Japan in the manufacturing industry.
Exploring the performances of the dual technique-based water hammer redesign strategy in water supply systems
Authors: Trabelsi Mounir , Triki Ali 
Published: June 2019

Abstract
This paper explored and compared the effectiveness of the inline and branching redesign strategies-based dual technique, implemented to enhance the conventional technique skills in terms of attenuation of positive and negative pressure surge magnitudes and limitation of the spreading of pressure wave oscillation period. Basically, this technique is based on splitting the single inline or branched plastic short-section, used in the conventional technique, into a couple of two sub-short-sections made of two distinct plastic material types. Investigations addressed positive and negative surge initiated water hammer events. Additionally, high and low density polyethylene materials were utilized for sub-short-section material. Results illustrated the reliability of the dual technique in protecting hydraulic systems from excessive pressure rise and drop, and evidenced that the (HDPE/LDPE) sub-short-sections' combination (where the former sub-short-section is attached to the sensitive region of the steel piping system parts, while the latter is attached to the second extremity of the steel piping system) is the most prominent configuration providing the best trade-off between pressure surge attenuation, and pressure wave oscillation period spreading. Lastly, it was found that the pressure head peak (or crest) and the pressure wave oscillation period values were markedly sensitive to the (HDPE) sub-short-section length and diameter.
The improved multi-criteria decision-making model for multi-objective operation in a complex reservoir system
Authors: Yang Zhe , Yang Kan , Wang Yufeng , Su Lyuwen , Hu Hu 
Published: June 2019

Abstract
In multi-objective reservoir operation, it is vital for decision-makers to select optimal scheduling schemes through efficient multi-criteria decision-making (MCDM) techniques. However, in the family of MCDM methods, it is difficult for the technique for order preference by similarity to an ideal solution (TOPSIS) to describe grey correlation, thus making decisions with less reliability. To this end, a framework supporting high-quality solutions' acquirement and optimal reservoir operation decision-making is established. The improved multi-objective particle swarm optimization (IMOPSO), a new efficient MCDM model based on TOPSIS and grey correlation analysis (GCA), and combination weighting method based on the minimum deviation (CWMMD) are included in the framework. The non-inferior solution set is efficiently obtained by IMOPSO and optimal decision information is provided for decision-makers using the MCDM model. Moreover, the CWMMD is used to determine weighting information of multiple evaluation indicators. Numerical simulations are conducted to verify the efficiency of the proposed methodology and support decision-making for multi-objective reservoir operation in Hongjiadu and Qingjiang basins. The results indicate that the proposed methodology can provide non-inferior scheduling solutions and decision-making instruction with higher reliability for multi-objective reservoir operation.
Use of detention basin for flood mitigation and urban requalification in Mesquita, Brazil
Authors: Jacob Ana Caroline Pitzer , Rezende Osvaldo Moura , de Sousa Matheus Martins , de França Ribeiro Luiza Batista , de Oliveira Antonio Krishnamurti Beleño , Arrais Cícero Matos , Miguez Marcelo Gomes 
Published: June 2019

Abstract
Unplanned urbanization is one of the main factors responsible for worsening flood-related problems in cities, increasing the frequency of flooding and flooding depths, consequently degrading both the natural and built environment. Considering this, the use of engineering techniques that reduce runoff and promote urban requalification are an efficient option for managing rainwater. This paper presents a case study of a flood control project using a storm water detention pond, designed to allow multiple uses of an urban space. The operation of the system is evaluated by an urban flow-cell model, known as MODCEL. This application seeks the best configuration for the layout of ‘Celso Peçanha’ Detention Basin, considering the local restrictions imposed by the City of Mesquita – Brazil, and optimized to damp storm flows resulting from rainfall events with return periods up to 50 years. The solution proposed considers the possibility of social urban space uses in flood control projects, revitalizing degraded areas and giving them multiple functions.
Clinical Usefulness of N-terminal Prohormone of Brain Natriuretic Peptide and High Sensitivity Troponin T in Patients with Heart Failure Undergoing Cardiac Resynchronization Therapy
Authors: Debska-Kozlowska Agnieszka , Ksiazczyk Marcin , Warchol Izabela , Lubinski Andrzej 
Published: June 2019

Background:
Cardiac resynchronization therapy (CRT) is a valuable intracardiac device-based treatment
option for a subgroup of patients with advanced heart failure (HF) and QRS prolongation. However, still a
significant proportion of patients do not benefit from CRT implantation, labeled as non-responders.

Objectives:
The aim of the present study was to evaluate the N-terminal prohormone of brain natriuretic peptide
(NT-pro BNP) and high sensitivity troponin T (cTnThs) value as predictors of CRT response in a 12-month observation.

Materials and Methods:
The study included 46 patients with HF and implanted CRT-D. Levels of NT-pro BNP
and cTnThs were assessed during a 12 month follow up.

Results:
46 consecutive patients (76% men) with a mean age of 64±8 were observed for 12 months. The CRT
response criteria was met by 26 patients (56,5%). A significant decline in the NT-pro BNP concentrations was
documented in responders (p=0.001). Moreover, ΔNT-pro BNP by at least 579 pg/ml had high sensitivity and
specificity for identifying the CRT responders. There were no statistically significant differences in the results of
cTnThs between the two study groups.

Conclusion:
The relative change in the level of NT-pro BNP by at least 43,5% allows to identify the responders
to CRT after 12 months of follow-up. Serial measurements of NT-pro BNP can be a valuable tool for monitoring
the effectiveness of CRT.
Reduction of Autophagic Accumulation in Pompe Disease Mouse Model Following Gene Therapy
Authors: McCall Angela L. , Stankov Sylvia G. , Cowen Gabrielle , Cloutier Denise , Zhang Zizhao , Yang Lin , Clement Nathalie , Falk Darin J. , Byrne Barry J. 
Published: June 2019

Background::Pompe disease is a fatal neuromuscular disorder caused by a deficiency in acid α-glucosidase, an enzyme responsible for glycogen degradation in the lysosome. Currently, the only approved treatment for Pompe disease is enzyme replacement therapy (ERT), which increases patient survival, but does not fully correct the skeletal muscle pathology. Skeletal muscle pathology is not corrected with ERT because low cation-independent mannose-6-phosphate receptor abundance and autophagic accumulation inhibits the enzyme from reaching the lysosome. Thus, a therapy that more efficiently targets skeletal muscle pathology, such as adeno-associated virus (AAV), is needed for Pompe disease.Objective::The goal of this project was to deliver a rAAV9-coGAA vector driven by a tissue restrictive promoter will efficiently transduce skeletal muscle and correct autophagic accumulation.Methods::Thus, rAAV9-coGAA was intravenously delivered at three doses to 12-week old Gaa-/- mice. 1 month after injection, skeletal muscles were biochemically and histologically analyzed for autophagy-related markers.Results::At the highest dose, GAA enzyme activity and vacuolization scores achieved therapeutic levels. In addition, resolution of autophagosome (AP) accumulation was seen by immunofluorescence and western blot analysis of autophagy-related proteins. Finally, mice treated at birth demonstrated persistence of GAA expression and resolution of lysosomes and APs compared to those treated at 3 months.Conclusion::In conclusion, a single systemic injection of rAAV9-coGAA ameliorates vacuolar accumulation and prevents autophagic dysregulation.
Sexuality and Reproductive Health Counseling in Adolescent Renal Transplant Recipients
Authors: Isa F. Ashoor , Ryan H. Pasternak 
Published: June 2019

Normal adolescence marks a period of significant physical, cognitive and psychosocial change. It is
characterized by transition from concrete to abstract thought processes and concern for risk taking behaviors. Adolescents
and young adults with chronic conditions are at a particular disadvantage and tend to be more vulnerable to risky behavior
than their healthy peers.
While there currently exists no information on the burden of sexually transmitted infections (STIs) in adolescent renal
transplant recipients, they present a particularly worrisome population as they are likely to engage in risk taking behavior
when they feel “normal” following transplantation to compensate for poor quality of life endured on dialysis. This is
further compounded by adolescents’ false perception that they are unlikely to acquire such infections, and the likely
improvement in libido and sexual functioning after transplantation. The potential for acquiring a sexually transmitted
infection is concerning given their immunocompromised status, and complex treatment regimens which might have
unfavorable interactions with STI treatments.
Also, unintentional pregnancy is likely to have a significant impact on their overall medical condition and social
functioning thereby impacting their long term allograft outcomes. As the pediatric nephrologist assumes a primary care
provider role for these patients following their renal transplant, it becomes increasingly important to be familiar with basic
reproductive health counseling techniques and available contraceptive methods on the market. Until consensus guidelines and
specific recommendations for reproductive health counseling are developed for adolescent renal transplant recipients, this
review provides a brief summary of available knowledge in those areas.