bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards a theory of platform dynamics
Authors: Cabral Luís 
Published: January 2019

AbstractI introduce a dynamic framework to analyze platforms. The (single) platform owner sets prices at the beginning of each period. Agents (buyers, sellers, readers, consumers, merchants, etc.) make platform membership decisions occasionally. I show that an optimal platform pricing addresses two externalities: across sides and across time periods. This results in optimal prices which depend on platform size in a nontrivial way. By means of numerical simulations, I examine the determinants of equilibrium platform size, showing that the stationary distribution of platform size may be bimodal, that is, with some probability the platform remains very low or takes very long to increase in size. I also contrast the dynamics of proprietary versus nonproprietary (i.e., zero‐priced) platforms, and consider the specific case of asymmetric platforms (one side cares about the other but not vice versa).
Persistent development of adomavirus and aquareovirus in a novel cell line from marbled eel with petechial skin haemorrhage
Authors: Pao Hui‐Yu , Wu Cheng‐Yu , Wen Chiu Ming 
Published: January 2019

AbstractIn Taiwan, a petechial haemorrhage disease associated with mortality has affected marbled eels (Anguilla marmorata). The eels were revealed to be infected with adomavirus (MEAdoV, previously recognized as a polyoma‐like virus). In this study, cell line DMEPF‐5 was established from the pectoral fin of a diseased eel. DMEPF‐5 was passaged >70 times and thoroughly proliferated in L‐15 medium containing 2%–15% foetal bovine serum at 20–30°C. Transcripts of neural cell adhesion molecule 1 and nestin genes, and nucleic acids of MEAdoV and a novel reovirus (MERV) in the cells were demonstrated by reverse transcription‐polymerase chain reaction analysis. Phylogenetic analysis revealed that the AdoV LO8 proteins mostly relate to adenovirus adenain, whereas MERV is close to American grass carp reovirus in Aquareovirus G, based on a partial VP2 nucleotide sequence. DMEPF‐5 cells are susceptible to additional viral infection. Taken together, the marbled eels with the haemorrhagic disease have coinfection with MEAdoV and MERV, and the pathogenic role of MEAdoV and MERV warrants research. DMEPF‐5 has gene expression associated with mesenchymal stem and progenitor cells and is the first cell line persistently infected with adomavirus and aquareovirus. DMEPF‐5 can facilitate studies of such viruses and haemorrhagic disease.
Prejudices towards people with intellectual disabilities: reliability and validity of the Italian Modern and Classical Prejudices Scale
Authors: Marcone R. , Caputo A. , Esposito S. , Senese V. P. 
Published: January 2019

AbstractBackgroundPrejudices and negative attitudes towards intellectual disabilities (IDs) may hinder social inclusion of ID individuals, limiting their well‐being. This study investigated the psychometric characteristics of the Italian Modern and Classical Prejudices Scale (MCPS‐IT) towards people with ID and the effects of gender, age and socio‐economic status (SES) on prejudices.MethodThe MCPS‐IT was administered to 474 adults (69% women, age range 18–70 years, M = 33.13) in conjunction with a questionnaire evaluating socio‐demographic information (SES), the contact and the education about ID people and the social dominance orientation.ResultsResults confirmed that Italian MCPS has a two‐factor structure that measures in a reliable and valid way prejudice towards people with ID. Multivariate analyses of variance confirmed a weak gender difference in both scales and age differences in modern scale. No SES differences were found.ConclusionThe Italian MCPS represents a valid scale that can be used to monitor the social context of people with ID.
Design of experiment with sensory data: A pragmatic data analysis approach
Authors: Pineau Nicolas , Moser Mireille , Rawyler Fabien , Lepage Mélissa , Antille Nicolas , Rytz Andreas 
Published: January 2019

AbstractIn the context of product development, the use of designs of experiments is a powerful approach to assess the impact of multiple parameters at a time while minimizing the number of trials and samples to be tested.When outcome measures are sensory profiles (samples × panelists × attibutes), it is proposed to analyze the data according to a two‐steps approach building on the use of Fisher's least significant difference (LSD) as an intuitive and easy‐to‐interpret descriptive tool. The approach quantifies the impacts of the investigated parameters on the multivariate sensory profiles and compares these impacts with a relevant LSD.To illustrate the approach, a fractional factorial design with 32 experiments—instead of 36′864 for a full factorial—has been used to assess the potential of 11 parameters of a vending machine to modulate sensory properties for various coffee types and dosages. With minimal effort, this study shows that machine parameters influence appearance, modulate specific odor and flavor attributes, but only marginally impact taste/aftertaste. This study illustrates the high actionability of a two‐step data analysis approach, which has actually proven to be efficient to drive product innovation and renovation in hundreds of cases covering multiple food and beverage categories.Practical applicationsThis approach has been applied for many years for past studies in which a design of experiment has been used with monadic sensory profiling as an outcome. It has been used with various product categories, with various levels of design complexity (2–15 parameters, with 2–8 levels each) and has proven to be very efficient to drive product innovation and renovation while optimizing the use of limited resources. Other types of data than sensory could be analyzed similarly as long as it is possible to get a relevant estimate of the measurement variability and that this variability is consided important in comparison with the production (pilot/kitchen) variability. Estimate of the variability can for instance come through replicates of (some of) the samples or through external data (e.g., a method validation procedure could provide information about the measurement variability of a given instrument).
Do body‐related sensations make feel us better? Subjective well‐being is associated only with the subjective aspect of interoception
Authors: Ferentzi Eszter , Horváth Áron , Köteles Ferenc 
Published: January 2019

AbstractAccording to the proposition of several theoretical accounts, the perception of the bodily cues, interoceptive accuracy and interoceptive sensibility, has a significant positive impact on subjective well‐being. Others assume a negative association; however, empirical evidence is scarce. In this study, 142 young adults completed questionnaires assessing subjective well‐being, interoceptive sensibility, and subjective somatic symptoms and participated in measurements of proprioceptive accuracy (reproduction of the angle of the elbow joint), gastric sensitivity (water load test), and heartbeat tracking ability (Schandry task). Subjective well‐being showed weak to medium positive associations with interoceptive sensibility and weak negative associations with symptom reports. No associations with measures of interoceptive accuracy were found. Gastric sensitivity as opposed to heartbeat perception and proprioceptive accuracy moderated the association between interoceptive sensibility and well‐being. Thus, subjective well‐being is associated only with the self‐reported (perceived) aspect of interoception but not related to the sensory measures of interoceptive accuracy.
Impact of a multicomponent physical activity intervention on cognitive performance: The MOVI‐KIDS study
Authors: Sánchez‐López Mairena , Cavero‐Redondo Iván , Álvarez‐Bueno Celia , Ruiz‐Hermosa Abel , Pozuelo‐Carrascosa Diana P. , Díez‐Fernández Ana , Gutierrez‐Díaz del Campo David , Pardo‐Guijarro María Jesús , Martínez‐Vizcaíno Vicente 
Published: January 2019

IntroductionThis study examined the impact of a multicomponent physical activity (PA) intervention (MOVI‐KIDS) on improving cognition in schoolchildren. This paper also analyzed the mediator role of motor fitness between MOVI‐KIDS and cognition.MethodsPropensity score analysis of data from a cluster randomized controlled trial (MOVI‐KIDS study). This analysis including 240 5‐7 years old children from nine schools in the provinces of Cuenca and Ciudad Real, Spain. MOVI‐KIDS program consisted of: (a) three weekly after‐school sessions of recreational non‐competitive PA lasting 60 minutes during one academic year, (b) educational materials for parents and teachers, and (c) school playground modifications. Changes in cognition (logical reasoning, verbal factor, numerical factor, spatial factor, and general intelligence) were measured. A propensity score cross‐cluster matching procedure and mediation analysis (Hayes's PROCESS macro) were conducted.ResultsAll cognitive variables pre‐post mean changes were significantly higher (P ≤ 0.05) in children from intervention schools than those from control schools (effect size ranged from 0.33 to 1.48). The effect of the intervention on the spatial factor and general intelligence was partially mediated by motor fitness (indirect effect = 0.92, 95% CI: 0.36; 1.65; and indirect effect = 1.21, 95% CI: 0.06; 2.62, respectively).ConclusionsThis study shows that a one‐school‐year multicomponent intervention consisting of a recreational non‐competitive PA program, educational materials for parents and teachers, and school playground modifications improved the cognition of first‐grade children. Further, our results suggest that the effect of the intervention on cognition was mediated by changes in motor fitness.
Risk and punishment: The recent history and uncertain future of actuarial, algorithmic, and “evidence‐based” penal techniques
Authors: Werth Robert 
Published: January 2019

AbstractIn recent decades, risk prediction has proliferated in the penal realm. Risk instruments currently guide an array of correctional decisions—such as participation in diversion programs, the provision of correctional services, and probation and parole supervision levels—and are being increasingly utilized or considered in pretrial detention and criminal sentencing. This article reviews empirical and theoretical accounts of the proliferation and effects of risk in the penal realm and also reflects on ongoing debates about the promises and perils of risk. Risk techniques have impacted the practices, discourses, and logics of punishment. Yet they have not triggered the abandonment of rehabilitative approaches (or retributive ones), nor have they replaced human judgment with a rationalized utopia or iron cage. This article also offers several interventions that complicate and further our understandings of risk. First, it highlights the complex entanglements between, on the one hand, actuarial and algorithmic risk instruments and, on the other, subjective, moral, and affective methods of evaluation. Second, it calls for increased attention to the performative effects of risk technologies: to the ways in which assessments not only report on but also create and alter the social world. The article concludes by reflecting on emerging topics and directions for future research.
Portuguese healthcare reforms in the context of crisis: External pressure or domestic choice?
Authors: Asensio Maria , Popic Tamara 
Published: January 2019

AbstractAs a result of the recent economic crisis, in 2011, Portugal signed a Memorandum of Understanding with the European Central Bank, the European Commission, and the International Monetary Fund (the “Troika”). In exchange for Troika's financial assistance, the Memorandum required the implementation of a specific set of reforms targeted at the healthcare sector. The literature on policy reforms in the context of crisis and conditionality argues that governments have restricted room to manoeuver in responding to external pressure. We challenge this view, finding that even in cases of conditionality and strong external pressures, crisis can be used as a window of opportunity for reforms substantially shaped by domestic policy choices. In the case of Portuguese health reforms, these choices were based on pre‐existing reform plans aimed on resolving country‐specific deficiencies of the healthcare system and were enabled by the two main political parties' strategies of tacit cooperation and blame avoidance. The article emphasizes the need for more fine‐grained analysis of welfare reforms in the crisis that pays equal attention to the institutional characteristics and the political context of the affected countries.
Mapping the face of young population in China: Influence of anatomical sites and gender on biophysical properties of facial skin
Authors: Song Yanqing , Pan Yao , Wang Huan , Liu Qi , Zhao Hua 
Published: January 2019

AbstractBackgroundFacial skin exhibits unique biophysical properties, which are influenced by anatomical regions and genders. The aim of this study was to comprehensively assess the regional and gender differences in facial skin biophysical parameters among Chinese population.Materials and MethodsThe 12 skin biophysical parameters at four distinct facial skin sites (forehead, cheek, canthus and chin) were measured in a normal population (n = 212) with 42 males and 141 females aged 18‐29 years living in Beijing. These parameters consisted of skin hydration, transepidermal water loss, sebum content, erythema/melanin indices, L*a*b* color, skin gloss and elasticity, all quantifying with non‐invasive instruments.ResultsThe results demonstrated that the characteristics of the facial skin were significantly different between the regions and genders. The forehead had weaker skin barrier function but secreted the most sebum content, while the cheek was the driest and brightest region on the face. The canthus was the most hydrated area and the chin displayed higher sebum secretion, darker skin color and less elastic. The females showed more hydrated, less oil, lighter and more elastic facial skin compared with males.ConclusionThis study indicates that the young Chinese facial skin significantly varies with face anatomical regions and differs between genders.
Evaluation of power extraction circuits on piezo‐transducers operating under low‐frequency vibration‐induced strains in bridges
Authors: Balguvhar Sumit , Bhalla Suresh 
Published: January 2019

AbstractThe concept of piezoelectric energy harvesting (PEH) provides a promising solution for perpetually running low‐power electronic devices such as wireless sensor networks by harvesting ambient vibrations generated from civil structures such as long span bridges, city flyovers, elevated metro corridors, which are constantly under dynamic loads. However, its successful industrial‐scale deployment on civil structures is still not realised because of the low‐frequency of vibrations (typically <5 Hz) encountered there, coupled with the low levels of voltage generation. The vast majority of PEH‐related studies have only focused on PEH configurations and geometries, Often entailing secondary structures. d31 mode, which is the most natural mode of excitation, has not been investigated in depth for piezo‐patches directly bonded on the main structure. Studies, which have focused on electronic conditioning circuitry, have been restricted to typically high‐voltage and high‐frequency scenarios only. This paper focuses on systematically studying the issues inflicting energy harvesting from the ambient vibrations induced flexural strains civil structures, such as city flyovers, using piezo elements in d31 mode. Vibration measurements are first undertaken from a typical city flyover consisting of steel girders supporting a reinforced concrete (RC) deck. The basic site measurements are employed to perform a laboratory‐based parametric study to investigate the influence of parameters such as vibration frequency, voltage, and circuit components like diodes on PEH. On the basis of the experimental results, it can be concluded that power in microwatts range can be typically harvested from these civil structures through directly bonded piezo patches in d31 mode. However, there are still issues associated with electronic circuitry accompanying harvesters, such as diodes and storage elements. The same are summarised and future directions envisioned.
Revisiting human cerebral blood flow responses to augmented blood pressure oscillations
Authors: Hamner J. W. , Ishibashi Keita , Tan Can Ozan 
Published: January 2019

Key points
Cerebral autoregulation is most effective in buffering against pressure fluctuations slower than 0.03 Hz (∼30 s). This suggests that frequency bands for characterizing cerebral autoregulation should be redefined
Low cross‐spectral coherence below 0.03 Hz highlights the limitations of transfer function approaches
Haemodynamic changes induced by lower body pressure could not fully explain the differences in autoregulation estimated from spontaneous vs. augmented fluctuations, and thus, observations of spontaneous fluctuations should not be relied on whenever possible.
AbstractThere is currently little empirical basis for time scales that are considered to be most significant in cerebrovascular counter‐regulation of changes in arterial pressure. Although it is well established that cerebral autoregulation behaves as a ‘high‐pass’ filter, recommended frequency bands have been largely arbitrarily determined. To test effectiveness of cerebral autoregulation, we refined oscillatory lower body pressure (LBP) to augment resting pressure fluctuations below 0.1 Hz by a factor of two in 13 young male volunteers, and thoroughly characterized the time and frequency responses of cerebral autoregulation. We observed that despite a threefold increase in arterial pressure power <0.03 Hz with oscillatory LBP, there was no change in cerebral blood flow power, indicating near perfect counter‐regulation. By contrast, in the range 0.03–0.10 Hz, both cerebral blood flow and arterial pressure power more than doubled. Our data demonstrate that cerebral autoregulation is most effective in buffering against pressure fluctuations slower than 0.03 Hz (∼30 s). This suggests that frequency bands of interest should be redefined and recording length should be increased considerably to account for this. Furthermore, low cross‐spectral coherence below 0.03 Hz, even when pressure fluctuations were augmented, highlights the uncertainty in transfer function approaches and the need to either report precision or use non‐linear approaches. Finally, haemodynamic changes induced by LBP could not fully explain the differences in autoregulation estimated from spontaneous vs. augmented fluctuations, and thus, observations of spontaneous fluctuations should not be relied on whenever possible.
Torsion of a uterine leiomyoma – a rare cause of hemoperitoneum; a case report and review of the literature
Authors: Levai Antonia Mihaela , Rotar Ioana Cristina , Muresan Daniel 
Published: January 2019

Uterine leiomyomas are common benign uterine tumors but by contrast, their acute complications are very rare. We present an unusual case of 38-year-old woman that came to the emergency department with acute abdominal pain. The ultrasound revealed hemoperitoneum, a uterus with two intramural fibroids and a tender inhomogeneous pelvic mass that seems to connect with the uterus. Computer tomographic (CT) examination raised the suspicion of a degenerated fibroid and hemoperitoneum. Emergency laparotomy was performed: the hemoperitoneum was determined by a degenerated fundal subserosalfibroid. Myomectomy was subsequently carried out. Even though this condition is extremely rare, every clinician has to bear in mind that acute fibroid complications can be a potential cause of acute abdominal pain that requires immediate surgery. The imagistic tools, ultrasound and CT are extremely helpful for the diagnosis.Due to its relative rarity in the second part of the article we have performed a review of the existing literature regarding the acute complications of fibroid torsion.
Fatty acid and lipid reference spectra
Authors: Taylor Michael J. , Zhang Katherine Y. , Graham Daniel J. , Gamble Lara J. 
Published: January 2019

The number of publications reporting lipid and fatty acid time-of-flight secondary ion mass spectrometry (ToF-SIMS) analysis has increased as ToF-SIMS is increasingly applied toward the analysis of biological systems. Tissue and cell analysis through ToF-SIMS typically involves collecting mass spectrometry images that are used to characterize the local distribution of lipids and fatty acids throughout the analyzed area. Complete and reliable sets of reference spectra are required for fatty acids and lipids in order to aid in the interpretation of ToF-SIMS data from tissues and cells. Here, we present the reference spectra for eight fatty acids and one lipid. This database contains positive and negative polarity spectra using a Bi3+ primary ion species.
At the request of the authors, this article is being retracted effective 26 October 2021.
Adiposity and risk of decline in glomerular filtration rate: meta-analysis of individual participant data in a global consortium
Authors: Chang Alex R , Grams Morgan E , Ballew Shoshana H , Bilo Henk , Correa Adolfo , Evans Marie , Gutierrez Orlando M , Hosseinpanah Farhad , Iseki Kunitoshi , Kenealy Timothy , Klein Barbara , Kronenberg Florian , Lee Brian J , Li Yuanying , Miura Katsuyuki , Navaneethan Sankar D , Roderick Paul J , Valdivielso Jose M , Visseren Frank L J , Zhang Luxia , Gansevoort Ron T , Hallan Stein I , Levey Andrew S , Matsushita Kunihiro , Shalev Varda , Woodward Mark 
Published: January 2019

AbstractObjectiveTo evaluate the associations between adiposity measures (body mass index,
waist circumference, and waist-to-height ratio) with decline in glomerular
filtration rate (GFR) and with all cause mortality.DesignIndividual participant data meta-analysis.SettingCohorts from 40 countries with data collected between 1970 and 2017.ParticipantsAdults in 39 general population cohorts (n=5 459 014), of which 21
(n=594 496) had data on waist circumference; six cohorts with high
cardiovascular risk (n=84 417); and 18 cohorts with chronic kidney disease
(n=91 607).Main outcome measuresGFR decline (estimated GFR decline ≥40%, initiation of kidney replacement
therapy or estimated GFR <10 mL/min/1.73 m2) and all cause
mortality.ResultsOver a mean follow-up of eight years, 246 607 (5.6%) individuals in the
general population cohorts had GFR decline (18 118 (0.4%) end stage kidney
disease events) and 782 329 (14.7%) died. Adjusting for age, sex, race, and
current smoking, the hazard ratios for GFR decline comparing body mass
indices 30, 35, and 40 with body mass index 25 were 1.18 (95% confidence
interval 1.09 to 1.27), 1.69 (1.51 to 1.89), and 2.02 (1.80 to 2.27),
respectively. Results were similar in all subgroups of estimated GFR.
Associations weakened after adjustment for additional comorbidities, with
respective hazard ratios of 1.03 (0.95 to 1.11), 1.28 (1.14 to 1.44), and
1.46 (1.28 to 1.67). The association between body mass index and death was J
shaped, with the lowest risk at body mass index of 25. In the cohorts with
high cardiovascular risk and chronic kidney disease (mean follow-up of six
and four years, respectively), risk associations between higher body mass
index and GFR decline were weaker than in the general population, and the
association between body mass index and death was also J shaped, with the
lowest risk between body mass index 25 and 30. In all cohort types,
associations between higher waist circumference and higher waist-to-height
ratio with GFR decline were similar to that of body mass index; however,
increased risk of death was not associated with lower waist circumference or
waist-to-height ratio, as was seen with body mass index.ConclusionsElevated body mass index, waist circumference, and waist-to-height ratio are
independent risk factors for GFR decline and death in individuals who have
normal or reduced levels of estimated GFR.