bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of cybersickness mitigation methods on behavior: a comparative study based on the skill–rule–knowledge model
Authors: Qi Shuaixin , Menozzi Marino 
Published: November 2024

AbstractCybersickness (CS) is a pressing issue in virtual reality (VR) systems. While various mitigation methods (MMs) have been developed to counteract CS, their effects on human behavior remain largely unexplored, raising concerns about their potential applications. Using Jens Rasmussen’s skill–rule–knowledge (SRK) model as a framework, our study investigated the effects of two widely adopted MMs—dynamic field of view and dynamic blurring—in VR. We compared these methods to a baseline condition where no MM was applied. We designed three VR tasks that align with the behavioral levels of the SRK model. In a within-subject study (N = 22), participants completed each task using these MMs. We measured task performance, CS symptoms, and locomotion control. Additionally, qualitative feedback was collected. Our results revealed that neither MM significantly alleviated CS across different VR scenarios. Furthermore, while some participants found MMs helpful, a larger portion reported visual hindrances, and a significant performance drop was measured in the skill-based task. More critically, participants indicated behavioral adaptations in response to the MMs, including changes in locomotion strategies and viewing behavior. Potential causes and implications were discussed. In conclusion, MMs offer promise, but their application necessitates a nuanced understanding of their impacts. We recommend a context-sensitive approach when designing and integrating MMs, prioritizing both maximizing CS mitigation and minimizing interference with the natural behaviors of users.
Does seismic isolation reduce the seismic vulnerability and the variability of the inelastic seismic response? Large-scale experimental investigation
Authors: Tsiavos Anastasios , Nunes Miguel Figueiredo , Stojadinovic Bozidar 
Published: November 2024

AbstractThis paper focuses on the large-scale experimental investigation of the seismic vulnerability and the variability of the inelastic seismic response of seismically isolated structures in comparison to conventional, fixed-based structures. The experimental setup comprises a steel structure consisting of two steel columns and a steel mass on top. The structure is seismically isolated using four friction pendulum bearings and subjected to an ensemble of strong recorded earthquake ground motion excitations using the shaking table of ETH laboratory. A mechanical clevis connection consisting of two hinges and two replaceable steel coupons is designed and constructed to facilitate the investigation of the seismic inelastic behavior of the structure for the selected ground motion record ensemble through the replacement of the damaged coupons after each shaking table excitation. Within this frame, the mechanical clevis connection presented in this study facilitates the parametric and experimental investigation of the seismic, inelastic behaviour of a wide range of structures and the experimental determination of their seismic fragility curves. The seismic vulnerability and the variability of the seismic response of the seismically isolated and the corresponding fixed-based structure are compared for three seismic hazard levels. The comparison of the response of the two structures demonstrates experimentally the ability of seismic isolation to reduce the seismic vulnerability and the variability of the seismic response of structures subjected to strong earthquake ground motion excitation, thus leading to the design of structures of higher performance, predictability and reliability in their response, even for extreme earthquake events.
Germline pathogenic variants in RNF43 in patients with and without serrated polyposis syndrome
Authors: Brinch Heidi Hesselø , Byrjalsen Anna , Lohse Zuzana , Rasmussen Andreas Ørslev , Karstensen John Gásdal , Kristiansen Britta Schlott , Jelsig Anne Marie 
Published: November 2024

AbstractSerrated Polyposis Syndrome (SPS) is characterized by multiple and/or large serrated polyps in the colon and an increased risk of colorectal cancer (CRC). The etiology is largely unknown, but in a subset of patients with SPS, monoallelic pathogenic variants in RNF43 are detected. To date, however, the penetrance and phenotypic spectrum of patients carrying pathogenic variants (PV) in RNF43 are poorly described. We present eight patients both with and without serrated polyps from four unrelated families with likely pathogenic variants (LPV) in RNF43 and compare the results to current literature. The patients were referred to genetic counseling due to suspicion of hereditary cancer. They underwent genetic testing with custom NGS gene panels including RNF43 as part of a routine genetic work-up. Three LPVs, one multi-exon deletion and two nonsense variants, were detected in four families. Family I had a history of CRC and serrated polyps, but in the three other families (II‒IV) there was no history of CRC or serrated polyps. Colonoscopies in the probands of these families did not reveal any serrated polyps and/or CRC despite some of them being relatively old. Our findings suggest that the penetrance of RNF43-related disease is much lower than previously thought, and raise questions about the connection between RNF43 and disease. The results highlight the complexity of genetic counseling in RNF43 positive families– particularly in families without polyposis. Further research is needed to elucidate the role of RNF43 in the risk of SPS and CRC.
The genetic landscape of Lynch syndrome in the Israeli population
Authors: Shtaya Aasem Abu , Nathan Sofia Naftaly , Kedar Inbal , Friedman Eitan , Half Elizabeth , Lidzbarsky Gabi , Levi Gili Reznick , Laish Ido , Katz Lior , Bazak Lily , Peretz Lilach Peled , Salmon Lina Basel , Douiev Liza , Kalis Marina Lifshitc , Schechter Menachem , Barzily-Rokni Michal , Samra Nadra Nasser , Abu-Freha Naim , Hagari-Bechar Ofir , Segol Ori , Mattar Samar , Barhom Sarit Farage , Mordechai Shikma , Rafid Shiri Shkedi , Shalev Stavit A. , Peretz-Yablonski Tamar , Levi Zohar , Bruchim Revital , Vinkler Chana , Bernstein-Molho Rinat , Lieberman Sari , Goldberg Yael 
Published: November 2024

AbstractDeciphering the spectrum and founder disease-causing variants (DCVs) in specific populations can shape and facilitate the diagnostic process of Lynch Syndrome (LS). The aim of this report was to comprehensively update on the genetic landscape of LS in the ethnically diverse Israeli-Jewish population. The cohort included 1080 carriers from 588 families; some from underrepresented, understudied Israeli ethnic groups recruited from 8 genetic institutes and high-risk clinics throughout the country. Variant classification was performed according to the American College of Medical Genetics criteria. A total of 157 DCVs were identified, 12 are reported here for the first time, and 9 reclassified. MSH2 DCVs were identified in 286 families (49%). Most DCVs (125/157, 80%) were noted in one or two families only. Sixteen DCVs, each detected in ≥ 5 families, and accounted for LS in 378/588 (64%) families. Constitutional mismatch repair deficiency (CMMRD) was diagnosed in 7 families. Twenty-five carriers (2.3%) had an additional DCV or risk alleles in another cancer susceptibility gene. In conclusion, MMR gene variant distribution in Israel is diverse. MSH2 is most commonly mutated due to founder DCVs. Though the 16 prevalent LS-associated DCVs were frequently detected in our cohort, none of them is frequently reported in the general population. These data should facilitate variant interpretation, spouse and cascade testing.
Assessing Whether Negative Parenting Cognitions Bias Parent Report of Preschoolers’ Externalizing Symptoms: A Regularized Moderated Non-Linear Factor Analysis Approach
Authors: Behrens Brigid , Edler Katherine , Valentino Kristin 
Published: November 2024

Abstract
Parent report is frequently used to assess children’s psychopathology, however, researchers have expressed concerns about the validity of parent reports. Some parental characteristics, attitudes, or beliefs may systematically bias a parent’s report of their child’s behaviors and functioning. Informed by social information processing models of parenting risk, parents with more difficulties reflecting on and interpreting their children’s behavior may be at risk for less accurate reports. The present study conducted two regularized moderated non-linear factor analyses with LONGSCAN data to examine how parents’ self-reported negative parenting cognitions were associated with structural parameters of parent-reported child aggression and attention problems. While differential item functioning (DIF) was present on the aggression and attention problems subscales as a function of negative parenting cognitions, the DIF was small in magnitude, inconsistent in directionality and did not significantly alter factor-level parameters. Negative parenting cognitions did demonstrate a small but significant negative impact on all latent externalizing factors (aggression and attention problems), such that caregivers with fewer negative parenting cognitions endorsed fewer items, and this was associated with a lower mean of each latent variable. Given that accounting for DIF did not contribute to meaningful differences in impact parameters or improve criterion validity, findings suggest that the aggression and attention subscales are functionally invariant to negative parenting cognitions, suggesting that externalizing symptoms can be reliability compared across parents of varying parenting cognitions.
Longitudinal Predictors of Adaptive Functioning in Emerging Adults with and without Autism Spectrum Disorder
Authors: Fossum Ingrid Nesdal , Øie Merete Glenne , Orm Stian , Andersen Per Normann , Skogli Erik Winther 
Published: November 2024

Abstract
Individuals with autism spectrum disorder (ASD) display heterogeneity in adaptive functioning, underscoring the need to identify predictors to inform clinical and scientific interventions. We investigated the longitudinal associations between an autism diagnosis, co-occurring psychopathology symptoms, executive functions (EF) and subsequent adaptive functioning in individuals with and without ASD (IQ > 70). Sixty-six individuals (26 with ASD, 40 without ASD) were assessed at baseline (mean age = 11.8 years, SD = 2.1) and at 10-year follow-up (mean age 21.4, SD = 2.3). The diagnostic evaluation comprised a comprehensive assessment of autism symptoms and emotional and cognitive functioning. Co-occurring psychopathology symptoms were assessed with two measures: self-reported depressive symptoms with the Short Mood and Feelings Questionnaire and parent-reported total problems with the Child Behavior Checklist 6–18. Participants completed neuropsychological tests to evaluate EF. We investigated adaptive functioning by using the Weiss Functional Impairment Rating Scale (WFIRS) which is a self-report measure of impairment in the following domains: family, work, school, life skills, self-concept, social and risk-taking. Among the emerging adults previously diagnosed with ASD, 46% reported living independently, 75% had at least one friend, and 71% were employed or in education. Individuals with ASD reported significantly lower adaptive functioning compared to individuals without ASD (WFIRS Total, Hedges’ g = 0.92). Greater EF difficulties in childhood/adolescence predicted lower adaptive functioning in emerging adulthood, surpassing the influence of autism diagnosis and co-occurring symptoms. The findings highlight the influential role of EF, implying that interventions targeting EF difficulties could improve long-term outcomes for individuals with ASD.
The Simons Observatory: Design, Optimization, and Performance of Low-Frequency Detectors
Authors: Mangu Aashrita , Westbrook Benjamin , Beckman Shawn , Corbett Lance , Crowley Kevin T. , Dutcher Daniel , Johnson Bradley R. , Lee Adrian T. , Kabra Varun , Prasad Bhoomija , Staggs Suzanne T. , Suzuki Aritoki , Wang Yuhan , Zheng Kaiwen 
Published: November 2024

Abstract
The Simons Observatory (SO) is a cosmic microwave background (CMB) experiment located in the Atacama Desert in Chile that will make precise temperature and polarization measurements over six spectral bands ranging from 27 to 285 GHz. Three small aperture telescopes (SATs) and one large aperture telescope (LAT) will house

$$\sim$$

∼

60,000 detectors and cover angular scales between one arcminute and tens of degrees. We present the performance of the dichroic, low-frequency (LF) lenslet-coupled sinuous antenna transition-edge sensor (TES) bolometer arrays with bands centered at 27 and 39 GHz. The LF focal plane will primarily characterize Galactic synchrotron emission as a critical part of foreground subtraction from CMB data. We will discuss the design, optimization, and current testing status of these pixels.
Microbial-induced structural changes in non-stoichiometric magnetite via radioanalytical methods
Authors: Vyhnáleková Silvia , Miglierini Marcel B. , Cesnek Martin , Štefánik Milan , Matúš Peter 
Published: November 2024

AbstractStructural alterations in non-stoichiometric magnetite induced by microorganisms are studied by nuclear methods. Magnetite samples were exposed to fungal strain known for its immobilization capabilities. Neutron activation analysis identified iron as the dominant element. The presence of maghemite in non-stoichiometric magnetite complicates the determination of iron sites by Mössbauer spectrometry. Mössbauer spectra recorded at 4.2 K display overlapping lines corresponding to tetrahedral and octahedral iron sites. Application of external magnetic field of 6 T improved the spectral resolution and revealed a presence of distinct sextets. Interaction with Aspergillus niger did not notably affect magnetite´s magnetic properties, indicating its stability.
Dynamic changes in the hippocampal memory index and biochemical indices in Sprague Dawley rats exposed to intrauterine kola nut
Authors: Atiba Foluso A. , Nkomozepi Pilani , Mbajiorgu Felix E. , Ihunwo Amadi O. 
Published: November 2024

Abstract
Kola nut is commonly consumed by pregnant women to suppress symptoms of morning sickness. This study investigated the effects of kola nut on the biochemical indices of the hippocampus and its dependent memory. Kola nut extract was fed to pregnant dams from the first day of their pregnancy until parturition. The following behavioral function tests were conducted: surface righting (SR); cliff avoidance (post-natal day [PND] 4, 5, 6 & 7); open field; novel object recognition and location; and radial-arm maze (PND 21 and 56). The levels of brain-derived neurotrophic factor (BDNF), acetylcholine (ACh), and malondialdehyde (MDA) of the matched hippocampal tissues were also checked in the pups. The kola nut-treated pups showed significantly reduced behavioral indices compared to the pups in the control group: lower postural balance, higher risk avoidance memory, and lower frequency in pivoting and rearing compared to that in the control group. However, the frequency of urine and fecal bolus was significantly lower in the pups in the control group than that in the treated pups. The discrimination ratio of the control group pups in novel object recognition (NOR) and novel object location (NOL) was significantly higher than that in the treated pups, and the time taken by the treated pups to complete RAM was significantly higher. The levels of ACh and BDNF in the treated pups were increased compared to that in control pups. A positive correlation was found between MDA and SR (r = 0.7207; p = 0.0437), grooming (r = 0.7707; p = 0.0252), and fecal bolus (r = 0.7606; p = 0.0284), as well as with the BDNF level in those treated with grooming (r = 0.7570; p = 0.0297). However, negative correlations between ACh and rearing (r = -0.8261; p = 0.0115) and fecal bolus (r = -0.8066; p = 0.0156) and a positive correlation with NOL (r = 0.8358; p = 0.0098) were observed. Based on these observations, the study concluded that Kola nut affects both biochemical and hippocampal memory profiles.
The use of lined paper in child education: impact of line presence on handwriting quality
Authors: Guilbert Jessica , Fernandez Jonathan 
Published: November 2024

AbstractSeveral surveys have shown that the type of paper used in classroom writing activities varies considerably between schoolteachers, school grades, and also countries. The present study aims to (1) evaluate if handwriting quality (both legibility and fluency) of school age children is better when they write on lined than on unlined paper and (2) explore whether fine motor and visuomotor skills of children could moderate the potential effects of lined paper. To this end, 34 third-grade students copied a text on blank and lined paper. All children were exposed to the two paper conditions (within-subject design). Handwriting legibility and fluency were evaluated using the Concise Assessment Scale for Children’s Handwriting. The students’ fine motor and hand–eye coordination skills were also assessed to determine whether these factors moderate the effect of line presence. The results revealed that handwriting legibility was better on lined paper than on unlined paper. However, fluency was not impacted by the presence of lines on the paper. Moderation analyses revealed that for third-grade students, lined paper similarly impacts handwriting performance regardless of their fine motor and visuomotor skills. The implications of these findings for guiding teachers in choosing a type of paper for classroom handwriting activities are discussed.
Toxicity, mutagenicity, and source identification of polycyclic aromatic hydrocarbons in ambient atmosphere and flue gas
Authors: Pan Shih Yu , Wu Ya Syuan , Chen Yu-Cheng , Hsu Yen-Shun , Lin Yu Chi , Hung Pao Chen , Chou Charles C.-K. , Chantara Somporn , Hsu Yuan Cheng , Chi Kai Hsien 
Published: November 2024

AbstractThis study aimed to assess the characteristics of particulate matter (PM) and polycyclic aromatic hydrocarbons (PAHs) from various stationary and mobile emission sources in Taiwan, with a focus on source apportionment and associated health risks. The northern power plant, equipped with bag filters operating at 150 °C, had significantly lower FPM and CPM levels (0.44 and 0.13 mg/m3, respectively) compared to the central and southern power plants, which used electrostatic precipitators operating at 250 °C (FPM, 1.45–8.35 mg/m3; CPM, 2.37–3.73 mg/m3). Additionally, emissions from diesel vehicles under both idle and high-speed conditions exhibited higher FPM levels (3.46–4.67 mg/m3) than gasoline vehicles (0.19–0.40 mg/m3). In terms of PAH toxicity, diesel vehicle emissions had significantly higher BaP-TEQ (87.3 ng/m3) and BaP-MEQ (25.9 ng/m3) levels compared to power plants (BaP-TEQ, 5.49 ng/m3; BaP-MEQ, 2.65 ng/m3). The highest ambient concentrations of PM2.5, BaP-TEQ, and BaP-MEQ were recorded at traffic sites, with values of 48 ± 36 µg/m3, 0.29 ng/m3, and 0.11 ng/m3, respectively. Differences in PAH distributions between stationary and mobile sources were influenced by factors such as pollution control technologies, combustion temperatures, and fuel types. Diesel vehicle emissions were dominated by benzo[g,h,i]perylene (BghiP), indeno[1,2,3-cd]pyrene (IND), benzo[a]pyrene (BaP), and benzo[b]fluoranthene (BbF) under idle conditions, while phenanthrene (PA), pyrene (Pyr), and BghiP were prevalent under high-speed conditions. Source apportionment conducted using principal component analysis (PCA) and positive matrix factorization (PMF) identified diesel and gasoline vehicles as the dominant contributors to atmospheric PAHs in Taiwan, accounting for 38% of the total, followed by coal-fired power plants at 35%. The highest lifetime excess cancer risk (ECR) of 2.5 × 10⁻5 was observed in traffic-dense areas, emphasizing the public health implications of vehicle emissions. The study adds credibility to the source apportionment findings, and the health risk analysis highlights variations across different regions, including traffic, urban, rural, and background zones.
The limits of curiosity? New evidence for the roles of metacognitive abilities and curiosity in learning
Authors: Chen Xiaoyun , Twomey Katherine E. , Hayes Miranda , Westermann Gert 
Published: November 2024

AbstractThe current study investigated how metacognitive abilities such as Knowledge Confidence (subjective prior knowledge estimate) and Correctness Confidence (appraisal of the likelihood of closing the gap) relate to curiosity, and examined the roles of these metacognitive measures and curiosity in learning. Using a blurred picture paradigm in which participants viewed blurred pictures and provided their metacognitive and curiosity estimates, the current study identified distinct connections between Knowledge Confidence, Correctness Confidence and curiosity. Our finding suggests that when Knowledge Confidence is at low or medium levels, curiosity is particularly heightened. In contrast, Correctness Confidence linearly influences curiosity such that the higher the Correctness Confidence, the greater the curiosity. We also find that learning is best predicted by a learner’s metacognitive appraisal of their knowledge gap, especially when they are on the verge of knowing, and this learning effect is independent of curiosity. These findings provide new evidence for the role of curiosity and metacognition in learning, highlighting limits of the effect of curiosity on learning.
Cosmopolitan identity, authority, and domestic support of international organizations
Authors: Schlipphak Bernd , Schäfer Constantin , Treib Oliver 
Published: November 2024

AbstractWhat effect does the institutional design of international organizations (IOs) have on their domestic support? In this article, we focus on interactions between citizens’ social identity and institutional characteristics that may have the potential to polarize citizens’ IO attitudes. We argue that citizens’ cosmopolitan identity makes them react in diametrically opposed ways to IO settings on the authority dimension. Transferring more authority to an IO may make citizens with higher levels of cosmopolitan identity more supportive of the IO, while citizens with lower levels of cosmopolitan identity should become even more skeptical. We test our expectations by conducting a factorial survey experiment in six different countries. The empirical results support our argument. As cosmopolitan identity is strongly connected to the newly evolving domestic cleavage regarding international cooperation and global governance, reforms to IO authority settings thus have the potential to further increase the polarization of domestic attitudes toward IOs.
Berufsbiografische Identitätsarbeit von Schulpädagogikprofessor:innen vor dem Hintergrund des Schulpraxiserfordernisses – eine explorative Interviewstudie
Authors: Rübben Ricarda 
Published: November 2024

ZusammenfassungDie Relationierung von Wissenschafts- und Berufsfeldbezug in der Lehrer:innenbildung hat nicht nur eine inhalts-, sondern auch eine personenbezogene Seite: In den meisten deutschen Bundesländern besteht formal das Schulpraxiserfordernis als zusätzliches Kriterium für die Berufung auf eine schulpädagogische Professur. Der Beitrag präsentiert vor diesem Hintergrund Ergebnisse einer Interviewstudie mit Schulpädagogikprofessor:innen, die über (keine) eigene(n) schulpraktische(n) Erfahrungen verfügen, und rekonstruiert vier Typen berufsbiografischer Identitätsarbeit: konservierend, kompensierend, transformierend und opponierend. Die eigene Berufsbiografie steht dabei im Dienst der selbstlegitimierenden Identitätsarbeit, wenngleich auch andere wahrgenommene Normen sich als bedeutsam zeigen. Die Ergebnisse werden vor dem Hintergrund disziplinpolitischer Diskurse diskutiert.