bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of ternary nanoadsorbent composites of graphene oxide, activated carbon, and zero‐valent iron nanoparticles for food applications
Authors: Bagheri Mahsa , Jafari Seid Mahdi , Eikani Mohammad H. 
Published: July 2019

AbstractIn this study, a ternary nanocomposite comprising graphene oxide and carbon loaded with zero‐valent iron nanoparticles was developed as a promising nanoadsorbent, especially for polyphenols available in food industry by‐products. The fabricated nanoadsorbents were characterized in terms of structural, morphological, and chemical attributes. Zero‐valent iron nanoparticles (nZVI) were produced by a modified method leading to the formation of nanoparticles below 50 nm. Also, active carbon was transformed to a needle‐like shape instead of its native shape so that the active surface area was drastically increased which favors the higher adsorption process. Moreover, the space between graphene oxide sheets was enhanced by ultrasonication so that more active carbon and nZVIs could be oriented between these sheets. Finally, the FTIR and Raman data demonstrated the formation of O‐H stretching groups and a D/G value of 0.85 corresponding to the maintenance of a desired structure of the graphene oxide sheets, respectively. To summarize, the developed nanocomposites can be employed as a promising tool for the adsorbance of food and beverage industry by‐products, especially polyphenols.
Geochemistry and U–Pb geochronology of K‐bentonites from the Pingliang Formation of the Upper Ordovician in Gansu, North China, and their tectonic implications
Authors: Xu Junjie , Wu Huaichun , Chu Zhuyin , Fang Qiang , Zhang Shihong , Yang Tianshui , Li Haiyan 
Published: July 2019

The Late Ordovician Pingliang Formation in the Guanzhuang section, located in the south‐western Ordos Basin, North China, contains several K‐bentonite layers, which are important for understanding the tectonic evolution of the south‐western Ordos Basin. This study provides new geochemical and SIMS U–Pb geochronological data for the K‐bentonites to establish the Ordovician high‐resolution chronostratigraphic framework for the Ordos Basin and to provide temporal constraints of major volcanic–magmatic activity. K‐bentonites in the succession yield U–Pb zircon ages of 457.6 ± 3.8 Ma and 454.8 ± 3.8 Ma (2σ analytical uncertainty), showing a depositional age in the Sandbian Stage (Late Ordovician). The result is consistent with the biostratigraphic and astrochronologic framework, achieving the intercalibration of different dating methods. The discrimination diagrams of whole‐rock Na2O+K2O against SiO2 and Zr/TiO2 against Nb/Y and Th/Yb against Nb/Yb and Th‐Hf‐Ta indicate that the K‐bentonites have obvious arc affinities. Based on the geological background, we conclude that the K‐bentonites in the south‐western Ordos Basin were mainly deposited during the development of the North Qilian‐North Qinling volcanic arc in the Sandbian.
Integrating clinical, morphological, and molecular data to assess prognosis in patients with primary myelofibrosis at diagnosis: A practical approach
Authors: Iurlo Alessandra , Elli Elena Maria , Palandri Francesca , Cattaneo Daniele , Bossi Anna , Cortinovis Ivan , Bucelli Cristina , Orofino Nicola , Brioschi Filippo , Auteri Giuseppe , Bianchi Paola , Fabris Sonia , Isimbaldi Giuseppe , Sabattini Elena , Baldini Luca , Gianelli Umberto 
Published: July 2019

AbstractCurrently available prognostic scoring systems in primary myelofibrosis (PMF) do not integrate clinical, histological, and molecular data, or they also required information on “other” mutations that are available in the clinical practice only in a very limited number of laboratories. In the present multicenter study, including 401 PMF patients, an integrated International Prognostic Scoring System (I‐IPSS) was developed by combining IPSS, grade of bone marrow fibrosis (GBMF), and driver mutations molecular status (MS) to define PMF prognosis at diagnosis. Four prognostic categories were identified: I‐IPSS–low risk (113 patients), I‐IPSS–intermediate‐1 risk (56 patients), I‐IPSS–intermediate‐2 risk (154 patients), and I‐IPSS–high risk (78 patients). Median overall survival was 26.7 years in I‐IPSS–intermediate‐1, 10.8 in I‐IPSS–intermediate‐2, and 6.4 in I‐IPSS‐high‐risk patients (log‐rank test <0.0001); instead, it was not reached in the I‐IPSS–low‐risk cohort because of the extremely low number of registered deaths. The addition of GBMF and MS to IPSS improved the efficacy for predicting the risk of death. Indeed, the sensitivity of I‐IPSS was significantly higher (P < .05) than that of IPSS, considering both total deaths and 5‐ and 10‐year mortality. This comprehensive approach allows clinicians to evaluate mutual interactions between IPSS, GBMF, and MS and identify high‐risk patients with poor prognosis who may benefit from aggressive treatments. More importantly, this integrated score can be easily applicable worldwide as it only required information that represent the good clinical practice in the management of PMF patients.
Impact of improved primary care on patient satisfaction: Results of a pilot study in the University of the Philippines
Authors: De Mesa Regine Ynez H. , Galingana Cara Lois T. , Marfori Jose Rafael A. , Rey Mia P. , Sundiang Nannette B. , Celeste Jayson T. , Dans Leonila F. , Dans Antonio Miguel L. , Catabui Jesusa T. 
Published: July 2019

SummaryPrimary care is generally perceived by the public as an inefficient, low‐quality source of health care in the Philippines. Taking a toll on local health policies, the repercussions of these views warrant a more holistic approach in understanding patient experience. This paper evaluates the impact of strengthening primary care services on patient satisfaction at the University of the Philippines Health Service (UPHS). A prevalidated 16‐item, 5‐scale questionnaire was distributed to 200 eligible patients at the start of the study in 2016 and then again in 2017. A significant increase of highly satisfied patients in 13 of 16 questionnaire items was recorded after primary care services in the facility were strengthened. The highest satisfaction scores were reported for overall wait times, coordination of care, and health advice. Our findings suggest that improvements in primary care services through digitalizing health records, financing laboratory and pharmaceutical services, and retraining staff accounts for significant improvements in patient satisfaction. This ultimately bears potential for better clinical outcomes in form of patient retention and long‐term care.
Transforming I into we in organizational knowledge creation: A case study
Authors: Ahn Jisun , Hong Ah Jeong 
Published: July 2019

AbstractThis study examined the process by which individual knowledge is transformed into organizational knowledge by clarifying the sensemaking process. Although several earlier studies on organizational learning have argued that knowledge sharing among members is important, research detailing the development of the knowledge‐sharing process is relatively rare. The current study addresses this gap by using a qualitative case study of a Korean government‐funded organization to examine the organizational knowledge‐sharing process. The findings suggest that learning for organizational knowledge generation depends on participation and communication and requires voluntary, dynamic interactions based on intersubjectivity among the organization's members. This study has important theoretical and practical implications for future research on organizational knowledge sharing and provides a new theoretical framework for the field of human resource development.
Experience on horizontal‐tube falling‐film evaporation simulation by lattice‐Boltzmann method
Authors: Bajalan Sima , Kouhikamali Ramin , Rahimian Mohammad Hassan 
Published: July 2019

AbstractComplex heat and mass transfers through falling‐film or spray‐film evaporation are widely used in chemical, refrigeration, petroleum refining, desalination, and food industries. Considering that microscopic effects, like surface tension, flow, mass, and heat transfers, are interdependent phenomena, the high‐precision simulation of falling‐film evaporation through a mesoscopic method is of great importance. In the current study, the lattice‐Boltzmann method and the phase‐field model with a proper source term are used for evaporation simulation in a horizontal‐tube falling film. Here, the curvature of the tube is captured by appropriate boundary conditions. Nondimensional numbers and the geometry of the model are determined in a range of practical values. By comparing the film thickness, mass, and heat transfer with valid references in the literature, an acceptable agreement is observed, which reveals the effectiveness of this method in understanding the details and predictions. Overall, the time evolution of temperature contours and streamlines during falling‐film evaporation approves the superiority of this method in keeping details along with lower difficulty and cost compared with the classical methods.
Does maternal warmth moderate longitudinal associations between infant attention control and children's inhibitory control?
Authors: Cioffi Camille C. , Leve Leslie D. , Natsuaki Misaki N. , Shaw Daniel S. , Reiss David , Neiderhiser Jenae M. 
Published: July 2019

AbstractAttention control (AC) is thought to play an important role in the development of inhibitory control (IC) in children, yet there are few longitudinal studies of this association. This study used a prospective parent–child adoption design (N = 361 children) to examine whether maternal warmth at child age 27 months moderated the link between AC during infancy and IC during childhood. Tobit regression analyses indicated that low levels of infant AC at 9 months predicted low levels of IC at 6 years, controlling for birth parent IC, prenatal risk, infant distress to limitations, child sex, and openness of adoption. Adoptive mother warmth at 27 months moderated this association. In the context of higher levels of maternal warmth, the longitudinal association between low AC and low IC was attenuated. Thus, high levels of early maternal warmth may help diminish the effects of extant risk for IC deficits.Highlights

The study examined associations between infant attention control, maternal warmth, and children's inhibitory control.
Using a parent–child adoption design, we found that maternal warmth moderated the association between infant attention control and school‐age inhibitory control.
Children with early risk for inhibitory control deficits may benefit from parental involvement in interventions that facilitate high maternal warmth during toddlerhood.
The transaction avoidance regime in the recast European insolvency regulation: Limits and prospects
Authors: Casasola Oriana 
Published: July 2019

AbstractIn the last decade, transaction avoidance in insolvency law has been in the limelight of the academic discussions. In particular, the scholarship has highlighted how the European Insolvency Regulation gives rise to several private international law issues. Moreover, the scholarship has explored solutions to these issues and proposed to harmonise the regime of transaction avoidance at European Union level. However, the recent legislative developments on the cross‐border insolvency law seem resistant to the proposed harmonisation. This article focuses on the transaction avoidance regime in the Recast European Insolvency Regulation. In particular, it seeks to evaluate whether the Recast has solved the issues arising within the original European Insolvency Regulation in relation to transaction avoidance. Secondly, it questions the suitability of the private international law approach to transaction avoidance in cross‐border insolvency within the European Union framework. The research suggests that the efforts required to the private international law framework to deal efficiently with transaction avoidance make the harmonisation of the regime of transaction avoidance at the European Union level a more appealing option.
Cervical intraepithelial neoplasia in women who had vaccination against HPV
Authors: Bogani Giorgio , Serati Maurizio , Leone Roberti Maggiore Umberto , Ditto Antonino , Gardella Barbara , Ferrero Simone , Spinillo Arsenio , Ghezzi Fabio , Raspagliesi Francesco 
Published: July 2019

AbstractObjectiveTo investigate the characteristics of women developing cervical intraepithelial neoplasia who had had a vaccination against human papillomavirus (HPV).MethodsA retrospective cohort study was carried out of women diagnosed with moderate or severe cervical dysplasia (CIN2+) in four Italian centers between 2015 and 2017. All women included had had previous bivalent or quadrivalent vaccination against HPV.ResultsThe present study included 43 patients affected by CIN2+. The median age was 28 (range, 21–41) years. Ten (23.3%) patients did not have a diagnosis of specific HPV type(s) involved: high‐risk HPV was detected in 7 (16.3%) women while HPV testing was negative in 3 (6.9%) women. Lesions related to HPV16 were found in two patients. HPV types covered by nonavalent vaccination were diagnosed in 27/33 (81.8%) women. HPV types not covered by nonavalent vaccination were diagnosed in 6 (18.2%) women. Co‐infections are most commonly detected in women with HPVs other than those included in the nonavalent vaccination (P=0.024).ConclusionCervical dysplasia occurring after HPV vaccination is a rare condition. Theoretically, nonavalent vaccination should improve protection against more than 80% of HPV‐related lesions compared to other vaccines.
Trolox prevents high glucose‐induced apoptosis in rat myocardial H9c2 cells by regulating GLUT‐4 and antioxidant defense mechanism
Authors: Davargaon Ravichandra Shivalingappa , Sambe Asha Devi , Muthangi V V Subramanyam 
Published: July 2019

AbstractRedox imbalance due to hyperglycemia is a causative factor for an increased generation of reactive oxygen species (ROS) that leads to mitochondrial dysfunction and the release of cytochrome‐c. The aim of the present study is to elucidate the functional role of oxidative stress (OS) in the induction of apoptosis in H9c2 cells in the hyperglycemic state through glucose transporter‐4 (GLUT‐4) regulation and antioxidant status. H9c2 cells were incubated with 15, 24, and 33 mM glucose for 24, 48, and 72 hr to induce hyperglycemic stress. Hyperglycemic episodes have significantly influenced GLUT‐4 mRNA regulation, depleted glutathione (GSH) and its associated enzymes, reduced cellular antioxidant enzymes (AOEs), caused nuclear condensation, and induced apoptosis by activating caspase‐9 and 3 and annexin V binding in a concentration and duration‐dependent manner. Trolox pretreatment significantly enhanced the GLUT‐4 mRNA and antioxidant defense mechanism, suppressed nuclear condensation, and prevented cytochrome‐c release, thereby reducing mitochondrial‐dependent apoptosis. The present study shows that the toxic effect of high glucose is significantly regulated and that OS induction can be prevented through a water‐soluble vitamin E analog “Trolox” treatment.
Theoretical insights into excited‐state process for the novel 2,3‐bis[(4‐diethylamino‐2‐hydroxybenzylidene)amino]but‐2‐enedinitrile system
Authors: Xu Lei , Zhang Tianjie , Yang Dapeng , Zhang Qiaoli 
Published: July 2019

AbstractIn this present work, we clarify the excited‐state intramolecular proton transfer (ESIPT) mechanism for 2,3‐bis[(4‐diethylamino‐2‐hydroxybenzylidene)amino]but‐2‐enedinitrile (BDABE) system. We present the fact that excited‐state single proton transfer can occur along with one hydrogen bond, even though BDABE form consists of two intramolecular hydrogen bonds. Based on the density functional theory and time‐dependent density functional theory methods, we theoretically investigate and elaborate the excited‐state intramolecular dual hydrogen‐bonding interactions. By simulating the electrostatic potential surface, we verify the formation of dual intramolecular hydrogen bonds for BDABE molecule in the S0 state. Furthermore, comparing the primary bond lengths and bond angles as well as the infrared vibrational spectra, we find that the double hydrogen bonds should be strengthened in the S1 state. When it comes to photoexcitation process, we discover the charge redistribution around hydrogen bonding moieties. The increased electronic density around proton acceptor plays the important roles in strengthening hydrogen bonds and in facilitating ESIPT reaction. In view of the possible ESIPT reaction paths (i.e., stepwise and synchronization double proton transfer) for BDABE molecule, we explored the S0‐state and S1‐state potential energy curves. This work explains experimental results and further clarifies the excited‐state behaviors for BDABE system.
Revisit of trinickel metal string complexes [Ni3L4X2] (L = dipyridylamido, diazaphenoxazine; X = NCS, CN) for quantum transport
Authors: Lin Geng‐Min , Cheng Ming‐Chuan , Liou Shun‐Jie , Tsao Ho‐Sung , Lin Chih‐Hsun , Lin Yi R. , Lee Gene‐Hsiang , Chen Chun‐hsien , Peng Shie‐Ming 
Published: July 2019

AbstractMetal string complexes contain a linear metal‐atom chain in which the metal centers are coordinated by four equatorial and two axial ligands. With a variety of transition‐metal elements and ligands, the structural framework drives the flourishing of molecular design and properties. The one‐dimensional configuration makes the compounds suitable for the studies of quantum transport across molecular junctions. In this study, we report the conductance measurements and transmission spectra of three trinickel metal strings, [Ni3(dpa)4(NCS)2] (1), [Ni3(dzp)4(NCS)2] (2), and [Ni3(dpa)4(CN)2] (3) (Hdpa = dipyridylamine, Hdzp, diazaphenoxazine) in which 1 is a prototypical compound, dzp of 2 represents an equatorial ligand more rigid than dpa of 1, and ─CN is an axial ligand with a ligand‐field effect stronger than ─NCS of 1. Measurement results of molecular junctions for 1, 2, and 3 are 2.69, 3.24, and 17.4 MΩ, respectively. The highest occupied molecular orbital and lowest unoccupied molecular orbital (HOMO–LUMO) gaps calculated by density functional theory in the gas phase for 1, 2, and 3 are about 2.65, 2.34, and 3.85 eV, respectively. Zero‐bias transmission spectra of 1–3 show that transmission peaks lie just above EFermi (the Fermi energy of the gold electrode), suggesting LUMO‐dominant transport pathways. The transmission peaks at EFermi are associated with LUMO+2 found in the gas phase. LUMOs in the free space are located at nearly 1 eV below EFermi. The shift of molecular orbitals from their isolated form and the alignment of LUMO+2 with the electrode Fermi level manifest the importance and significant of the electrodes' self‐energy on electron transport.
A novel approach for modelling pattern and spatial dependence structures between climate variables by combining mixture models with copula models
Authors: Khan Firdos , Spöck Gunter , Pilz Jürgen 
Published: July 2019

AbstractSpatiotemporal dependence structures play a pivotal role in understanding the meteorological characteristics of a basin or subbasin. This further affects the hydrological conditions and, consequently, will provide misleading results if these structures are not taken into account properly. In this study, we modelled the spatial dependence structure of three climate variables, maximum and minimum temperature and precipitation, throughout the Monsoon‐dominated zone of Pakistan. For temperature, six meteorological stations have been considered, for precipitation we used the results of four meteorological stations. For modelling the dependence structure between temperature and precipitation at multiple sites, we utilized C‐Vine, D‐Vine and student t‐copula models. For temperature, multivariate mixture normal distributions, and for precipitation, the gamma distribution, have been used as marginals under the copula models. The models were calibrated by utilizing the 20 years daily data from 1981 to 2000, and for validation, we used the data for 10‐year period from 2001 to 2010. The simulations were performed for each variable separately, conditioned on spatial neighbours. A comparison was made between the different copula models, on the basis of observational and simulated patterns and spatial dependence structures, the performance was evaluated for the validation period. The results show that all copula models performed well; however, there are subtle differences between them. The copula models captured the patterns and spatial dependence structures between climate variables, however, the t‐copula showed poor performance in reproducing the dependence structure with respect to magnitude. It was observed that important statistics of observed data have been closely approximated except a few maximum values for maximum temperature and minimum values for minimum temperature. Probability density functions of simulated data follow closely the pattern of observational data. These methods can be combined with statistical downscaling models to improve their performance, particularly in modelling the dependence structure between climate variables at multiple sites.
Periodontal condition, changes in salivary biochemical parameters, and oral health‐related quality of life in patients with anorexia and bulimia nervosa
Authors: Chiba Fernando Y. , Sumida Doris H. , Moimaz Suzely A.S. , Chaves Neto Antônio H. , Nakamune Ana C.M.S. , Garbin Artênio J.I. , Garbin Cléa A.S. 
Published: July 2019

AbstractBackgroundAnorexia and bulimia nervosa can have significant effects on oral health. Assessment of enzyme concentrations in saliva can be useful for obtaining information on molecular biomarkers for the prevention, monitoring, and diagnosis of oral diseases. This study investigated the periodontal condition, changes in salivary biochemical parameters, and oral health‐related quality of life (OHRQoL) in patients with anorexia and bulimia nervosa.MethodsThe study comprised 60 women patients who attended a Brazilian medical school. Participants were divided into two groups: patients with anorexia and bulimia nervosa (ABN; n = 30) and control patients (CN; n = 30). Oral clinical examinations were carried out to evaluate the periodontal condition by Community Periodontal Index, and interviews using the Oral Health Impact Profile (OHIP‐14) were conducted to assess OHRQoL. Saliva samples were collected for the evaluation of salivary concentrations of total protein, alanine aminotransferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH), and thiobarbituric acid reactive substance (TBARS), and salivary flow rate.ResultsPeriodontal condition in the ABN group was significantly worse than that in the CN group. The ABN group showed significantly higher salivary concentrations of total protein, AST, ALT, and LDH than the CN group. There was no significant difference in the salivary concentrations of TBARS among the groups. The OHIP‐14 score was higher in the ABN group than in the CN group.ConclusionAnorexia and bulimia nervosa are associated with poor periodontal condition, elevated salivary concentrations of total protein, AST, ALT, and LDH, decreased salivary flow rate and a significant adverse impact on OHRQoL.