bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leucocytosis in penetrating trauma (abdominal and thoracic/osseous): a transversal study in Juarez, México
Authors: Díaz-Rosales Juan de Dios , Enríquez-Domínguez Lenin , Aguayo-Muñoz Balthazar , Díaz-Torres Beatriz 
Published: May 2019

Introduction: The abdominal trauma is an important cause of morbility and mortality, abdomen is the 3th zone of human anatomy more affected by traumatism that require surgery and hospitalization. Evaluation of penetrating abdominal trauma aims to identify patients that requires surgical treatment. Objective: The objective of this study was to compare white blood cells levels in patients with penetrating abdominal trauma isolated and associated with osseous and/or thoracic injury. Patients and methods: A transversal study comparing two groups of abdominal penetrating trauma patients; penetrating abdominal trauma isolated versus penetrating abdominal trauma associated with osseous and or thoracic injury. We examined the level of white blood cells as a factor associated with major injury. Results: Our study showed a difference in mean of white blood cells count between the two groups that was statistically significant (p=0.01). A positive relationship between penetrating abdominal trauma associated with osseous and or thoracic injury was found. Conclusion: A significant elevation in white blood cells count in penetrating abdominal trauma associated with osseous and or thoracic injury is observed in comparison with penetrating abdominal trauma isolated.
Síndrome de Sjögren, más que un ojo seco
Authors: Aránzazu Ceballos Andrés David , Escobar Restrepo Jerónimo , Ramírez Pulgarín Sergio 
Published: May 2019

El síndrome de Sjögren primario (SSp) es una exocrinopatía autoinmune de gran importancia en la actualidad, ya que afecta entre 0.2 al 3 % de la población general. Al SSp se le ha atribuido una estrecha relación con la susceptibilidad genética de cada individuo, debido a la presencia de alelos del HLA DR y HLA DQ y a la influencia ambiental que conllevan al desarrollo de dicha enfermedad.El SSp se caracteriza por pérdida de la tolerancia central, la cual origina una epitelitis por la infiltración de células linfomonocitarias, proceso que tiene como consecuencia atrofia acinar de las glándulas exocrinas. Las manifestaciones clínicas fundamentalmente se dividen en dos grupos: manifestaciones glandulares como xerostomía, xeroftalmia e hipertrofia parotídea y manifestaciones extraglandulares como artralgias, neuropatía, fatiga, entre otras.El SSp es un reto para el clínico, ya que requiere un alto índice de sospecha debido a la amplia gama de manifestaciones, pero apoyándose en una adecuada implementación e interpretación de ayudas diagnósticas y siguiendo los criterios de clasificación se puede realizar un diagnóstico oportuno.El tratamiento depende de la sintomatología y del compromiso que genere. Este se basa en tres pilares fundamentales: medidas generales para evitar la sequedad, estimulantes de secreción y la medicación cuando existe compromiso sistémico.En los últimos años se ha despertado el interés acerca del uso de anticuerpos monoclonales en el tratamiento del SSp, los cuales han llevado a resultados prometedores como el uso de anti CD20.
Frecuencia de infecciones vaginales y lesiones intraepiteliales en las usuarias de los laboratorios clínicos de Dinámica IPS de la ciudad de Medellín (Colombia), 2005-2010: estudio descriptivo
Authors: Zapata Martinez Juan Felipe , López López Lucelly , Tirado Otálvaro Andrés Felipe , Gómez Upegui Luis Jaime , González, Bacte Juan David , Velásquez Vergara Sandra Milena , Velásquez Vergara Sandra Milena , Molina López Yulieth 
Published: May 2019

Objetivo: determinar la frecuencia de infecciones vaginales y lesiones intraepiteliales los resultados de laboratorio de las usuarias de los laboratorios clínicos de Dinámica IPS de la ciudad de Medellín atendidas entre el 2005 y el 2010.Materiales y Método: estudio descriptivo transversal con fuentes secundarias de los resultados de pruebas realizadas a usuarias de Dinámica IPS atendidas en el periodo de estudio en el que se evaluaron variables como la edad y los resultados de citología vaginal (n= 261 789), Gram (n= 70 447) y directo de flujo vaginal (n= 89 527). Se excluyeron registros con información incompleta. Se realizó análisis estadístico con medianas y proporciones.Resultados: del total de muestras analizadas(n=261 789), el 1,99% correspondían a lesiones escamosas, de éstas el 0,038% corresponde a muestras positivas de cáncer de cuello uterino confirmada por patólogo; el 8,01% corresponde a lesiones intraepiteliales de alto grado y el 36,13% a lesiones escamosas de bajo grado. En el examen de flujo vaginal por directo se encontraron 14 803 pruebas positivas (16,51%) para vaginitis por hongos, 19 079 (21,31%) para vaginosis bacteriana y 414 (0,46%) para vaginitis por Trichomona; en el Gram se observó que las infecciones vaginales generadas por Gardnerella ocupan la mayor frecuencia con 19 186 resultados positivos (27,23%).Conclusiones: los datos encontrados con relación a las frecuencias de lesiones escamosas intraepiteliales y para las infecciones vaginales guardan relación con lo reportado en la Literatura nacional; sin embargo, para el casos del ASCUS se encuentra variación, probablemente por las características mismas de este tipo de atipias.
Epidemiología, etiología y clasificación de la enfermedad vascular cerebral
Authors: Gonzales Piña Rigoberto , Landinez Martinez Daniel Alfredo 
Published: May 2019

La Enfermedad Vascular Cerebral (EVC) es una pérdida súbita de la función neurológica como resultado de una alteración focal del flujo sanguíneo cerebral debido a una isquemia o hemorragia. La EVC se ubica como la tercera causa de muerte en Estados Unidos estando solo por debajo de la cardiopatía y el cáncer a quienes se les atribuye la mayor tasa de muertes. Este estudio de revisión busca presentar la actualidad con respecto a la epidemiología, etiología y clasificación de la EVC de acuerdo a investigaciones recientes que presentan nuevos datos, con el propósito de tener mayor conocimiento de esta enfermedad y promover que la EVC es antes que nada prevenible. Una mejor comprensión de las causas de la EVC en adultos mayores puede llegar a mejorar aspectos como el manejo clínico de los pacientes y además las estrategias de prevención y a futuro las políticas en el cuidado de la salud. En esta revisión, se explora la evidencia de estudios en sujetos humanos relacionados con nuevos factores de riesgo, métodos de prevención y finalmente como la EVC afecta el funcionamiento cognitivo en general, específicamente la memoria de trabajo, función que esta altamente relacionada con la capacidad para organizar, planear e iniciar una tarea cognitiva.
Abuso sexual en mujeres de 10 a 13 años en el Valle del Cauca, Colombia.
Authors: Moran Garreta Liced Marcela , Pinzón Gómez Elisa Maria , Muñoz Villa Víctor Hugo , Lesmes Duque Maria Cristina , Victoria García Maria Constanza 
Published: May 2019

Objetivo: Describir características del abuso sexual en mujeres de 10 a 13 años en el Valle del Cauca notificados a través del sistema de vigilancia en salud pública. Materiales y métodos: Estudio observacional de corte transversal, la población objeto fueron mujeres entre 10 y 13 años víctimas de abuso sexual notificadas al sistema de vigilancia en salud pública del departamento del Valle del Cauca. A través de análisis secundario, se evaluaron características sociodemográficas de la víctima, información del agresor e información relacionada con el evento. Resultados: Se seleccionó el universo de mujeres de 10 a 13 años violentadas sexualmente que correspondió a 431 casos. 17,9% de las víctimas eran afrodescendientes 58,2% pertenecían al régimen subsidiado, y 6,3% no tenían afiliación. 75,9% eran estudiantes y 15,1% residían en la zona rural. La edad promedio de los agresores fue 24,9 años, 94,1% del sexo masculino y 94% eran personas conocidas. En términos de atención en salud, 23,9% fueron hospitalizadas, 61,3% de los abusos fueron reportados a las autoridades, 53,6% recibieron atención en salud mental y 13,6% anticonceptivos de emergencia. Conclusiones: El abuso sexual afecta principalmente población con condiciones sociales y económicas bajas. La mayoría de victimarios son personas menores de edad por lo general con vínculos familiares. Se hace imperativo fortalecer la atención integral en salud que se brinda a las víctimas y la complementariedad con los sectores de justicia y protección.
Становлення модного показу як складової модного туру та туристичної атракції, основаної на використанні костюма
Authors: Артеменко М. П. 
Published: May 2019

The purpose of the study is to identify the peculiarities of the development of fashion shows as tourist attractions based on the use of costume, as well as the definition of their place among the components of the modern fashion tour. The study contains historiographical and systematic analysis of publications on selected topics, periodization of the fashion show as a recreational and tourist resource, depending on the stages of increasing the scale of the audience, as well as systematization of the components of the modern fashion tour. The analysis of publications, which considers the history of becoming a fashion show through the prism of increasing the tourist potential. As a result, the theoretical study revealed a close relationship between the fashion industry and the tourism industry, which manifests itself in the early stages of development. The summary of the analysis of the formation of a fashion show as a recreational and tourist resource is presented in the form of a chronological scheme, in which, over decades, fundamental differences in the presentation of a costume on the podium can be traced, as well as five stages of increasing the scale of the audience, which indirectly reflect the growth of tourist and recreational interest to this type of activities. In addition, the place of fashion show in the systematic list of components of modern fashion tours is determined, among which, in addition to fashion shows, there are proposals for the purchase of goods from well-known brands with special discounts, visiting costume exhibitions, workshops and salons of designers of clothing, leading educational institutions in fashion, etc. Thus, the costume and all stages of its design and presentation are the key conceptual links around which a number of fashionable recreational and tourist proposals are formed. The chronology of the formation of a fashion show as a recreational and tourist resource based on the use of the costume has been built and the stages of its development have been determined depending on the stages of increasing the scale of the audience. Reasonably leading the fashion show among the components of the events of a modern fashion tour. The obtained results determine the possibilities of a deeper understanding of the role of a suit and ways of presenting it on the podium in modern lists of recreational and tourist events, and can also be used in the training of design specialists, in teaching disciplines related to costume design and fashion history, and in the practical activities of designers, costume artists, tourism managers and the like.
MODIFIED SINGLE-SIDED LAPAROSCOPIC EXTRAVESICAL ANTIREFLUX OPERATION
Authors: Dubrov V. I. , Bondarenko S. G. , Kagantsov I. M. 
Published: May 2019

Introduction. Laparoscopic techniques have been applied to ensure surgical treatment of the vesicoureteral reflux (VUR) in children during the last decades. We present the experience of using the laparoscopic extravesical antireflux standard and ureter-fixed modified surgery.Materials and methods. A multi-center prospective experimental clinical historical cohort two-group study of patients with III–V stage primary VUR. The basic group consisted of 48 children who had a unilateral laparoscopic extravesical surgery when the ureter was fixed according to the developed technique. 44 children who had a surgery according to the standard technique were included into the control group.Results. Complete VUR removal was noted in 100% of patients from the basic group and 81.2% of patients from the control group (р <0.01). Preservation of the megaureter with complete reflux resolution was seen in 1 child only (2.1%) from the basic group who had V stage VUR (p=0.2).Conclusions. Laparoscopic extravesical antireflux is a safe and effective surgery. Distal ureter fixation reduces the rate of VUR recurrences.
PROBLEMS AND WAYS OF SOLVING THE MEDICAL ASPECTS OF CIRCUMCISION
Authors: Murtuzaaliev Z. N. , Mahachev B. M. , Murtuzaaliev N. P. 
Published: May 2019

Purpose: the study was aimed at analyzing the complications that occur during circumcision and estimate the effectiveness of the developed original method of this surgery.Materials and methods. Over 6,000 observed results of circumcision performed in boys from 3 regions of the country using both conventional, and original author techniques were analyzed. They included saving resection of the prepuce preserving the inner leaf of the prepuce without sutures.Results. The first group included 3,223 boys who had a surgery following the technique made at the clinic when 0.3% of unsatisfied results were obtained. The second group consisted of 3,115 children who had a conventional surgery at medical institutions and at home with unsatisfactory results diagnosed in 7.6% of patients.Conclusions. The main reasons for complications in circumcision are the lack of a proper preoperative preparation of the surgical field, deviation from the conventional surgery technique and inad equate postoperative care. The sutureless circumcision technique developed by the author enabled to achieve minimum of complications.
BEZOARS OF THE GASTROINTESTINAL TRACT IN CHILDREN
Authors: Grigovich I. N. , Savchuk O. B. , Savchuk M. O. , Derbenev V. V. 
Published: May 2019

The purpose of the study: evaluation of the results of surgical treatment of children with bezoars of the gastrointestinal tract.Materials and methods. Over the past 18 years, we have observed 6 children with bezoaris (girls-4, boys-2). Of these, 5 children with trichobezoirs of the stomach and intestines and one child with polybezoar – rags, bandages. Age fluctuated from 8 to 13 years. Only one girl was at the age of 3 years. With careful collection of anamnesis, it was found that everyone had a bad habit of chewing the ends of the hair. Only one child suffering from a severe CNS lesion had a polybekoar. It is difficult to determine the exact period of existence of trihobezoars. Children were registered with pediatricians for gastritis 2–3 years; perhaps these were the first signs of the formation of trichobezoara in the stomach.Results. Of the six children operated 5 (3 girls and 2 boys). At one girl of 12 years the tri-chaser in the size of 4 sm was in a stomach, and its tail descended in duodenum. This bezoar removes endoscopically. The remaining 5 children were operated. All the children recovered.Conclusions. With trihobezoare stomach possible endoscopic removal. However, the main method of treating children with bezoars of the gastrointestinal tract is surgical.
Non-technical skills for surgeons, the NOTSS
Authors: Shah Jay N 
Published: May 2019

The cognitive and social skills are important categories of ‘nontechnical skills (NTS)’ for surgeons’ performance and is increasinglybeing appreciated and accepted widely.1 Adverse events duringhospital stay occur in up to 10-17% patients, half of which can beprevented because they occur not for the lack of knowledge,technical skills or equipment but simply due to failure of NTS.
Surgery (39.6%) and medication (15.1%) related events accounts formajority of these adverse events. Errors in nonoperativemanagement are responsible and causes more adverse events thansurgical technique. In a review of fatal medical accidents by the Japan Medical SafetyResearch Organization categorized the events into technical skills,NTS and inevitable progress of disease. It revealed that the causesof deaths were NTS in 34 (46.6%), disease progression in 33 (45.2%)and only in 2 (5.5%) due to technical skills and 2 (5.5%)undetermined. Further analysis of NTS revealed that the causes ofdeaths in 33 (97.1%) cases were due to errors in three areassituationawareness 14 (41.2%), team work 8 (23.5%) and decisionmaking 3 (8.8%). Thus, training in certain specific subcategories ofNTS may effectively reduce adverse events.
The NTS behavior includes ‘cognitive, social and personal skills’ thatcomplement technical skills for safe and efficient task performanceof individual and team in care of patients.5,6 The surgical NOTECHSbehavioral marker includes four categories- ‘leadership andmanagement, teamwork and cooperation, problem solving anddecision making, situation awareness among sub-team (of nurses,surgeons and anesthetists)’ and are important part of surgical skillsnecessary for surgeons and the team to become aware to managetheir situation appropriately.
Outcome of mini percutaneous nephrolithotomy ‘miniPCNL’ in children
Authors: Shrestha Samir , Maskey Pukar , Shah Jay N 
Published: May 2019

Introductions: Renal stone disease is one of the common urological disorders with prevalence approximately 2-3% in the general population and the incidence in children is increasing at a rate of 4% per year. Miniaturization of endoscopic instruments, minimally invasive endoscopic procedures of mini percutaneous nephrolithotomy (miniPCNL) in children is increasingly used. This study was conducted to assess the outcome of miniPCNL in pediatric population.
Methods: This retrospective study analyzed the outcome of miniPCNL in children below 18 years of age from August 2015 to July 2018 at Patan Hospital, Nepal. Ethical approval was obtained. Outcome was assessed descriptively on stone localization, puncture success, stone clearance, bleeding requiring transfusion, gross hematuria, urosepsis, operative time, hospital stay, mortality and need of second procedures.
Results: A total of 26 patients underwent miniPCNL, mean age 10.8±5.45 years (1-18 years), mean operative time was 122±26.03 minutes and mean hospital stay was 3.2±1.12 days. Postoperative transfusion was required in 1 (2.6%), gross hematuria occurred in 1 (2.6%), no urosepsis, no conversion to open surgery. Complete stone clearance was achieved in 22 (84.61%) patients. Mortality was nil. Second procedure was required in 4 (15.38%) to achieve residual stone clearance.
Conclusions: Our study shows miniPCNL is an effective and safe procedure with minimal morbidity for the treatment of pediatric renal stones.
Testing of the mutagenic potential of N-(γ-aminobuturyl)-1-aza-15-crown-5 hydrochloride in Ames test microplate modification
Authors: Golovenko M. Ya. , Larionov V. B. , Basok S. S. , Reder A. S. 
Published: May 2019

In recent years, studies in the field of chemical mutagenesis have undergone significant development, due to the introduction of a large number of different chemicals and scientific advances in the creation and use of new test systems, allowing a complete assessment of both mutagens themselves and their metabolites. The aim of the work was to determine possible induction of gene mutations under influence of hydrochloride N-(γ-aminobuturil)-1-aza-4,7,10,13-tetraozacyclopentadecan (TOCPD), which has nootropic, anxiolytic and anticonvulsant activity.
The ability of TOCPD to induce gene mutations was evaluated in Ames test on strains Salmonella typhimurium ТА 98 (frame shift mutations) and ТА 100 (substitution point mutations). The compound was used at concentrations of 10, 100, 250, 500 and 1000 μg/ml. Standard mutagens were 2-nitrofluoren for Salmonella typhimurium ТА 98 and sodium azide for Salmonella typhimurium ТА 100 in test without metabolic activation. In an activation variant a microsomal activating mixture was used (S9 mix). In tests with activation for both strains, 2-aminoantracene was used. The µAmes kit, Moltox (USA) and Muta-ChromoPlate kit (Canada) were used in the work. The results were evaluated by the number of wells with mutated cells with medium color changing from purple to yellow.
The obtained data showed that in the control and according to the action of corresponding mutagens, the percentage of wells with mutated cells corresponded to the standard parameters determined by protocol of the microplate test. For the action of TOCPD compound, no gene mutations were detected in both S. typhimurium ТА 98 and ТА 100 strains within the concentrations used.
STATUS KANDUNGAN SULFORAPHANE MICROGREENS TANAMAN BROKOLI (Brassica oleracea L.) PADA BERBAGAI MEDIA TANAM DENGAN PEMBERIAN AIR KELAPA SEBAGAI NUTRISI
Authors: Widiwurjani Widiwurjani , Guniarti Guniarti , Andansari Putri 
Published: May 2019

Brokoli merupakan salah satu tanaman yang mengandung mengandung sulforaphane. Sulforaphane merupakan suatu senyawa antioksidan untuk mencegah penyakit kanker. Kandungan sulforaphane merupakan salah satu indikator kualitas sayuran. Sayuran dalam bentuk microgreens mempunyai kandungan nutrisi seperti folat, vitamin C, vitamin K, zat besi dan tinggi potasium (kalium), serta mengandung senyawa antioksidan seperti sulforaphane. Microgreens merupakan produk inovasi budidaya pertanian perkotaan. Microgreens dapat dibudidayakan di lahan sempit secara vertikultur (bertingkat) dan tidak membutuhkan radiasi matahari yang terlalu banyak. Microgereens merupakan sayuran yang dipanen pada usia yang sangat muda. Pemanenan dilakukan saat daun sejati pertama muncul dengan kotiledon sepenuhnya melebar. Microgreens tanaman brokoli ditanam di Green House Fakultas Pertanian UPN “Veteran” Jawa Timur pada bulan November-Desember 2018. Penelitian disusun menggunakan Rancangan Acak Lengkap (RAL) dengan dua faktorial yaitu media tanam yang terdiri dari 4 level dan pemberian air kelapa terdiri dari 2 level yang menghasilkan 8 kombinasi dan diulang sebanyak 3 kali. Status kandungan sulforaphane meningkat dengan adanya penambahan nutrisi dari air kelapa pada semua media tanam yang diujikan. Hasil terbaik diperoleh pada perlakuan media tanam cocopeat dengan pemberian air kelapa (M2S2).
Expression Collagen I and III in Anterior Vaginal Women with and without Pelvic Organ Prolapse
Authors: Basyar Basyar , Irianta Trika , Rauf Syahrul 
Published: May 2019

Objective: To find out the expression of collagen [ and III in the anterior vaginal wall of women with and without pelvic organ prolapse (POP).
Method: The research was a cross sect ional study, conducted in Dr. Wahidin Sudiro Husodo hospital and its networks from January 1, 2011 to April 1, 2012. The case group consisted of 35 women with POPlevel III and IV.The contro l group consisted of35 women without POP. The expression of collagen I and III were examined by immunohistochemical test with the stain ing of antibody of collagen I (mouse monoclonal collagen lab 90395 ) and the antibody collagen III (Mu167 4i).The data was then analyzed by using a computer statistic program with a significance level of 0.05.
Result: It was found that in the group of women with POP, there were 28 cases of expression collagen III (84%), which is significantly higher than in women without POP, found in only 20 cases (58.8%), with p=0.02. Meanwhile, in the group of POP, 9.1% of subjects showed moderate expre ssion of collagen I, significantly less compared to the expressio n in the contro l group (35.3%), with p=0.007. For the ratio of collagen I and III, the result was weak in women with POP(58.5% ) while in the control group, the result was high (85.7%).
Conclu sion: In terms of collagen I and III expression, there was no significant difference between the two groups.
Keywords: collagen I, collagen III, pelvic organ prolapse, vaginal wall