bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reversal of DIRECT-ACTING Oral Anticoagulants in Urgent Surgery of the Proximal Aorta: case Series and Review of the literature
Authors: Zimmermann Eric , Ameer Fawzi , Worku Berhane , Avgerinos Dimitrios 
Published: December 2018

Introduction:
Proximal aorta interventions impose significant bleeding risk. Patients on concomitant
anticoagulation regimens compound the risk of bleeding in any surgery, but especially cardiothoracic interventions.
The employment of direct-acting oral anticoagulants (DOAC), namely those that target clotting factors II or
X, has expanded at a precipitous rate over the last decade. The emergence of their reversal agents has followed
slowly, leaving clinicians with management dilemmas in urgent surgery. We discuss current reversal strategies
based on the available published data and our experience with proximal aortic surgery in patients taking DOACs.

Literature Search:
We performed a review of literature and present three cases from our experience to offer
insight into management strategies that have been historically successful. A review of literature was conducted
via PubMed with the following search string: (NOAC or DOAC or TSOAC) and (aorta or aortic or (Stanford and
type and a)).

Case Presentation:
We present three case presentations that illustrate the importance of DOAC identification and
offer management strategies in mitigating associated bleeding risks in urgent or emergent surgeries.

Conclusion:
Treatment teams should be aware of the technical limitations of identifying and reversing DOACs.
In view of the tendency toward publishing positive outcomes, more scientific rigor is required in the area of
emergency DOAC reversal strategies.
Characterization of Antibacterial-Producing Endophytic Fungi of Syzygiumpolyanthum Leaves
Authors: Burhamzah Rahmita , Alam Gemini , Rante Herlina 
Published: December 2018

Background:
Endophytic fungi live in plants’ tissue and can produce the same bioactive
compounds as its host plant produces. Syzygiumpolyanthum leaves have known to be one of
the antibacterial compound producers.

Aim and Objective:
This study aimed to characterize morphologically, microscopically, and
molecularly the antibacterial-producing endophytic fungi of Syzygiumpolyanthum leaves.

Methods:
The isolation of endophytic fungi was done by fragment planting method on PDA medium.
The antibacterial screening was performed using the antagonistic test as the first screening
followed by the disc diffusion test method. The morphological characterization was based on isolate’s
mycelia color, growth pattern, margin, and surface texture of the colony, while the microscopic
characterization was based on its hyphae characteristics. The molecular characterization of
the isolate was done by nitrogen base sequence analysis method on nucleotide constituent of ITS
rDNA genes of the isolate.

Results:
The results found that isolate DF1 has antibacterial activity against E.coli, S.aureus,
P.acne, and P.aeruginosa, with the greatest inhibition at 10% concentration of broth fermentation
extract on S.aureus with a diameter of inhibition of 13.77 mm.

Conclusion:
Based on macroscopic, microscopic, and molecular characterization, DF1 isolate is
similar to Ceriporialacerate.
The Economic Dispatch of Wind Integrated Power System based on an Improved Differential Evolution Algorithm
Authors: Liu Haiqing , Qu Jinmeng , Li Yuancheng 
Published: December 2018

Background:
As more and more renewable energy such as wind energy is connected to
the power grid, the static economic dispatch in the past cannot meet its needs, so the dynamic economic
dispatch of the power grid is imperative.

Methods:
Hence, in this paper, we proposed an Improved Differential Evolution algorithm (IDE)
based on Differential Evolution algorithm (DE) and Artificial Bee Colony algorithm (ABC). Firstly,
establish the dynamic economic dispatch model of wind integrated power system, in which we consider
the power balance constraints as well as the generation limits of thermal units and wind farm.
The minimum power generation costs are taken as the objectives of the model and the wind speed is
considered to obey the Weibull distribution. After sampling from the probability distribution, the
wind speed sample is converted into wind power. Secondly, we proposed the IDE algorithm which
adds the local search and global search thoughts of ABC algorithm. The algorithm provides more
local search opportunities for individuals with better evolution performance according to the thought
of artificial bee colony algorithm to reduce the population size and improve the search performance.

Results:
Finally, simulations are performed by the IEEE-30 bus example containing 6 generations.
By comparing the IDE with the other optimization model like ABC, DE, Particle Swarm Optimization
(PSO), the experimental results show that obtained optimal objective function value and power
loss are smaller than the other algorithms while the time-consuming difference is minor. The validity
of the proposed method and model is also demonstrated.

Conclusion:
The validity of the proposed method and the proposed dispatch model is also demonstrated.
The paper also provides a reference for economic dispatch integrated with wind power at the
same time.
Enhanced Composite Nonlinear Control Technique using Adaptive Control for Nonlinear Delayed Systems
Authors: Singh Sonal , Purwar Shubhi 
Published: December 2018

Background and Introduction:
The proposed control law is designed to provide fast reference
tracking with minimal overshoot and to minimize the effect of unknown nonlinearities and
external disturbances.

Methods:
In this work, an enhanced composite nonlinear feedback technique using adaptive control
is developed for a nonlinear delayed system subjected to input saturation and exogenous disturbances.
It ensures that the plant response is not affected by adverse effect of actuator saturation, unknown
time delay and unknown nonlinearities/ disturbances. The analysis of stability is done by
Lyapunov-Krasovskii functional that guarantees asymptotical stability.

Results:
The proposed control law is validated by its implementation on exothermic chemical reactor.
MATLAB figures are provided to compare the results.

Conclusion:
The simulation results of the proposed controller are compared with the conventional
composite nonlinear feedback control which illustrates the efficiency of the proposed controller.
APPLICATION OF E-MARKETING IN ENTREPRENEURSHIP LEARNING FOR STUDENT WITH INTELLECTUAL DISABILITY
Authors: Purwanta Edi , Hulfah Hulfah 
Published: December 2018

Abstract:Entrepreneurship learning is a process that equips students in developing their soul, attitude, and carefulness in seeing opportunities and organizing the sustainability of a business. This study set out to investigate the effect of e-marketing towards the understanding of marketing in entrepreneurship learning of senior high school students with mild intellectual disability through e-marketing. A quantitative approach with one group pretest-posttest design was used in this study. A total of 24 students with mild intellectual disability from three schools in Magelang and Temanggung Regency participated in this study. A purposive sampling was applied in selecting these senior high school students. The data in this study were collected through a test. Anon-parametric statistical analysis technique, i.e. Wilcoxon sign rank test, was used to analyze the data. Based on data analysis performed, the calculated Z value is -4.115 with Asymp.Sig (2-tailed) 0.000 at significant (α) 0.05 level. The results indicated that the students mean score after the treatment was significantly higher than their average score before the treatment. It is then concluded that the application of e-marketing has an effect in improving the understanding of marketing in entrepreneurship learning of senior high school students of with mild mental disability. Keyword:e-marketing, entrepreneurship learning, intellectual disability PENERAPAN E-MARKETING DALAM PEMBELAJARAN KEWIRAUSAHAAN SISWA TUNAGRAHITA RINGAN TINGKAT SMA Abstrak: Pembelajaran kewirausahaan merupakan pembelajaran yang membekali siswa dalam mengembangkan jiwa, sikap, kejelian dalam melihat peluang dan pengorganiasasian dalam keberlangsungan suatu usaha. Penelitian ini bertujuan untuk mengetahui pengaruh e-marketing terhadap pemahaman pemasaran dalam pembelajaran kewirausahaan siswa tunagrahita ringan tingkat SMA melalui e-marketing.Penelitian menggunakan pendekatan kuantitatif dengan desain one group pretest-posttest. Subjek penelitian berjumlah 24 siswa tunagrahita ringan dari tiga sekolah di tiga kota yang berbeda yakni Magelang, and Temanggung. Sampel diambil secara purposif, yaitu siswa yang berada di tingkat SMA.Teknik pengumpulan data menggunakan tes.Analisis data menggunakan teknik analisis statistic nonparametric Wilcoxon sign rank test. Berdasarkan analisis data yang dilakukan, diperoleh nilai Z adalah -4,115 dengan Asymp.Sig (2-tailed) 0,000 pada taraf signifikan (α) 0,05. Hasil dari penelitian menyatakan bahwa nilai rata-rata sesudah diberikan perlakuan lebih tinggi secara signifikan daripada hasil nilai rata-rata sebelum diberikan perlakuan.Hal itu dapat disimpulkan bahwa penerapan e-marketing berpengaruh meningkatkan pemahaman pemasaran dalam pembelajaran kewirausahaan siswa tunagrahita ringan tingkat SMA. Kata kunci: e-marketing,pembelajarankewirausahaan, tunagrahita
İLKÖĞRETİM YAPILARINDA ERGONOMİ KAVRAMININ İNCELENMESİ: TİP PROJE İLKOKULU İLE TASARIM PROJESİ İLKOKULUNUN KARŞILAŞTIRILMASI
Authors: TAPKI Sinem , CANBAY TÜRKYILMAZ Çiğdem 
Published: December 2018

Eğitim kurumsal olarak ilkokulda başlamaktadır. Okula
başladıktan sonra çocuklar, zamanlarının çok büyük bir çoğunluğunu okulda
geçirmektedirler. Bu anlamda ilkokullarda çocukların motivasyonu, verimliliği,
fiziksel ve bilişsel gelişimi için; okulların fiziksel koşulları büyük öneme
sahiptir. Eğitim ortamlarında ergonomik düzenlemelerin yapılması; ortamlarının
kalitesini verimini arttıracak, öğretmen ve öğrencilerin daha iyi bir ortamda
öğrenme yaşantıları geçirmelerini ve kalıcı öğrenmelerden deneyim kazanmalarını
kolaylaştıracaktır. Çalışmanın amacı, ilkokul binalarının ergonomik açıdan
kullanım durumunu ortaya
koymaktır. Bu amaca ulaşabilmek için şu sorulara cevap aranmıştır: Fiziki
mekanlar
öğrenci sayısına göre yeterli midir?
Bu birimler mekansal, görsel, işitsel, termal konfor şartlarını sağlamakta mıdırlar? Kullanılan araç-gereç ve donanımlar ergonomik açıdan yeterli midir?
Bu soruların cevapları, çalışmada seçilen tip proje ilkokulu ve tasarım projesi
ilkokulunda aranmıştır.
Türkiye’de milyonlarca öğrencinin öğrenim gördüğü ilköğretim okulları daha çok
aynı
mimari özellikte yapılan tip proje
olarak tasarlanmaktadır. Bu tip projeler
Türkiye genelinde coğrafi şartlar gözetilmeksizin tüm bölge ve illerde yapılmaktadır. Diğer taraftan, ender olmakla birlikte
tasarlanan özgün ilkokul projeleri de bulunmaktadır.
Bu çalışmada, tip proje
ilkokulu ve
tasarım proje
ilkokulunun
ergonomik konfor şartlarına uygun olup olmadığı irdelenmiştir. Kullanılan
araç-gereç ve donanımların ergonomik açıdan yeterli olup
olmadığı gibi sorulara cevaplar aranmıştır.
Çalışma sonunda tip proje ilkokulu ile tasarım projesi ilkokulu ergonomik açıdan karşılaştırılmış ve
farklılıkları ortaya konmuştur.
SEKTÖRE İLİŞKİN KURUMSAL İMAJ ALGILARININ KARİYER YAPMA İSTEKLERİ ÜZERİNE ETKİSİ: TURİZM ÖĞRENCİLERİNE YÖNELİK BİR UYGULAMA
Authors: TÖRE BAŞAT Hümeyra , AKAGÜNDÜZ Makbule 
Published: December 2018

Amaç: Günümüzde ekonomik, sosyal ve
teknolojik alanlarda meydana gelen gelişmeler sonucu işletmeler artan rekabet
koşulları altında faaliyetlerini sürdürmektedirler. İşletmelerin gelecekte
varlıklarını sürdürebilmeleri ve akıllarda kalıcı bir marka olabilmeleri için
kaliteli mal ve hizmet üretiminin yanı sıra güçlü bir imaj algısına da sahip olmaları
gerekmektedir. İşletmelerin kamuoyunda
nasıl tanındıklarına ve nasıl bilindiklerine ilişkin genel yargılar mevcuttur.
Öznel ve nesnel bilgilerden oluşan bu yargılar sonucu kurumsal imaj oluşur.
Genel anlamda kurumsal imaj, bireylerin kurum hakkında öngörülen düşünce,
sezgi, izlenimlerin ve algılarının tümüdür. Kurumsal imaj üzerinde oluşan
algılar, bireylerin yaşamlarında etkili olan kariyer yapma isteklerini de
etkilemektedir. Bireyler sürdürdükleri yaşamlarında ve işlerinde devamlı
ilerleme kaydederek yükselebilmeyi, daha iyi statüye erişebilmeyi ve parlak bir
kariyer sahibi olabilmeyi istemektedirler. Bu nedenle bireylerin sektöre
ilişkin imaj algıları ile kariyer yapma istekleri arasındaki muhtemel ilişkinin
belirlenmesi önemli gözükmektedir. Turizm sektörünün emek yoğun bir nitelik
taşıması, insan odaklı bir yapının ön plana çıkmasını sağlamaktadır. Bu nedenle
araştırma, üniversitede turizm eğitimi alan öğrencilerin sektöre yönelik imaj
algılarının, kariyer yapma isteklerine etkilerini ortaya çıkarmak amacıyla
yapılmıştır.Yöntem: Araştırmanın evrenini, Ege
Bölgesi’nde Turizm Fakültelerinde Turizm eğitimi gören öğrenciler
oluşturmaktadır. Çalışmada nicel araştırma yöntemi tercih edilmiştir. Konuyla
ilgili olarak turizm fakülteleri öğrencileri üzerinde bir anket uygulaması
gerçekleştirilmiştir. Elde edilen veriler ile katılımcıların ifadelere vermiş
oldukları yanıtların frekans, yüzde ve aritmetik ortalamaları belirlenmiştir. Değişkenler
arası farklılıkları belirlemek üzere kurumsal imaj ile kariyer eğilimlerinin
demografik özelliklere göre değişip değişmediği (iki grup için) t testi ve (üç
veya daha fazla grup için) varyans analizi (One Way ANOVA) ile test edilmiştir.Bulgular: Sektöre yönelik kurumsal imaj ile
kariyer yapma isteği arasında anlamlı bir etki tespit edilmiştir. Öğrencilerin
kurumsal imaj algıları kariyer yapma isteklerini pozitif etkilemektedir.

Sonuç: Elde edilen sonuçlara göre
öğrencilerin sektöre yönelik kurumsal imaj algılarının kariyer yapma istekleri
arasındaki ilişki/etki korelasyon ve regresyon analizi ile tespit edilmiş olup,
katılımcıların sektöre yönelik imaj algılarının kariyer yapma istekleri
arasında anlamlı bir ilişki olduğu görülmektedir. Bununla birlikte değişkenlere
ait aritmetik ortalamaların düşük olmasına bağlı olarak regresyon analizinde
kurumsal imaj algılarının kariyer yapma isteklerine ilişkin toplam varyansın
küçük bir kısmını açıkladığı da görülmektedir.
Лерканідипін у лікуванні артеріальної гіпертензії: різні аспекти дії в клінічному досвіді
Authors: Rekovets O.L. 
Published: December 2018

Актуальність. Одним з нових антагоністів кальцію III покоління є лерканідипін, який завдяки високій ліпофільності й судинній селективності здатний забезпечувати антигіпертензивний ефект, що розвивається поступово й триває понад 24 години. Матеріали та методи. У дослідження було включено 20 пацієнтів із м’якою й помірною артеріальною гіпертензією (середній рівень систолічного (САТ)/діастолічного артеріального тиску (ДАТ) — 149,12 ± 1,42/91,92 ± 0,93 мм рт.ст.). Критеріями включення в дослідження були: вік чоловіків і жінок від 18 до 75 років, м’яка й помірна есенціальна артеріальна гіпертензія. У 20 пацієнтів із м’якою й помірною артеріальною гіпертензією ми досліджували вплив лерканідипіну (Леркамен виробництва компанії «Берлін-Хемі», Німеччина) в дозі 20 мг один раз на добу на показники офісного артеріального тиску, артеріального тиску при добовому моніторуванні, центрального артеріального тиску й пружно-еластичні властивості артерій. Результати. У групі монотерапії лерканідипіном зниження офісних САТ/ДАТ становило 12,35/8,18 мм рт.ст. (р < 0,01 для обох значень), частота серцевих скорочень зросла на 4,72 уд/хв. Загалом цільовий офісний артеріальний тиск < 140/90 мм рт.ст. було досягнуто в 76,47 % хворих на фоні монотерапії лерканідипіном, при добовому моніторуванні тиск < 130/80 мм рт.ст. було досягнуто в 76,47 %. У групі пацієнтів, які лікувалися лерканідипіном, за даними добового моніторування АТ спостерігалося достовірне зниження середньодобових показників САТ/ДАТ — на 8,65 ± 1,91/9,06 ± 2,17 мм рт.ст., р < 0,01 для обох значень, а також достовірно зросла частота серцевих скорочень у нічний час — на 5,05 ± 1,86 уд/хв, р < 0,05. Достовірним було зменшення індексу часу для САТ і ДАТ за весь період, за денний період, зменшення нічного ДАТ. Висновки. За даними офісного вимірювання артеріального тиску, лікування на основі лерканідипіну приводило до достовірного зниження офісного САТ/ДАТ на 12,35/8,18 мм рт.ст. За даними добового моніторування АТ, лікування на основі лерканідипіну в дозі 20 мг на добу достовірно знижувало середньодобовий САТ/ДАТ на 8,65/9,06 мм рт.ст. Центральний артеріальний тиск на фоні лікування лерканідипіном 20 мг на добу знизився достовірно на 12,18 мм рт.ст. Частка пацієнтів, які досягли цільового рівня офісного артеріального тиску й артеріального тиску при добовому моніторуванні, була однаковою — 76,47 %. Не спостерігалося достовірного впливу терапії лерканідипіном на зміни варіабельності серцевого ритму. Прийом лерканідипіну добре переносився хворими.
Perbedaan Pola Menyusui Bulan Pertama Ibu Melahirkan Seksio Sesarea Dibandingkan Melahirkan Normal di Rumah Sakit Sayang Bayi
Authors: Nurmayani Winda , Julia Madarina , Prawitasari Shinta 
Published: December 2018

Background: exclusive breastfeeding should be provided until 6 months of age, but the fact proves that the pattern of breastfeeding has decreased. The pattern of the first month lactation is a critical period for the survival of the subsequent breastfeeding, so it is necessary to make efforts to maintain the duration of breastfeeding because the success of the first month breastfeeding will increase mothers’ confidence to continue breastfeeding.Objective: To determine differences in the pattern of the first month breastfeeding in mothers who gave birth by cesarean section compared to those by vaginal delivery in Rumah Sakit Sayang Bayi (Baby Friendly Hospital)Method: Type of research is comparative observational with a prospective cohort design using a quantitative approach. The research was conducted in Baby Friendly Hospital of RSUD (General Hospital) Mataram City. Total sample 120 consisted of 60 mothers giving birth the caesarean section and 60 mothers vaginal delivery. The independent variable of giving birth by Cesarean Section and vaginal delivery, dependent variable pattern the first month of breastfeeding and external variables age, parity, employment, the incidence of antepartum and postpartum. The sampling technique using consecutive sampling. Analysis of the data used is univaribel, bivariate using Chi-square and Fisher's exact test and multivariable logistic regression and stratification testResult and Discussion: There was no significant correlation between the mode of delivery and the patterns of the first month breastfeeding by including a variable of employment with a value of OR (95% CI) = 1.6 (0.63 to 4.17) and there was a decrease in the value of OR (95% CI ) from 2.5 (1.05 to 5.94) to 1.6 (0.63 to 4.17); there was also no significant correlation when involving the variable of the incidence of ante partum and post partum with the value of OR (95% CI) = 1.7 (0.45 to 6.26) and OR (95% CI) = 2.3 (0.96 to 5.53), respectively.Conclusion: : There is no difference patterns of breastfeeding mothers first month who gave birth cesarean section compared to normal birth. Caesarean section would affect the pattern of the first month breastfeeding if cesarean section deliveries occurred at housewives and mothers who did not experience the incidence of ante partum. Keywords: pattern of breastfeeding; vaginal deliveries; caesarean section; breast milk;
Keanekaragaman, Deteksi dan Peranan Tikus terhadap Penularan Toksoplasmosis di Kabupaten Banjarnegara
Authors: Wijayanti Tri , Marbawati Dewi 
Published: December 2018

Tikus dapat menjadi reservoir penyakit yang disebabkan oleh parasit protozoa, salah satunya adalah toksoplasmosis. Toksoplasmosis merupakan penyakit zoonosis yang disebabkan oleh Toxoplasma gondii dengan Felidae seperti kucing sebagai hospes definitifnya. Infeksi toksoplasmosis pada kucing dapat diperoleh dari hewan kecil disekitarnya seperti tikus. Artikel ini bertujuan untuk mengukur keberhasilan penangkapan, mengidentifikasi spesies tikus yang tertangkap, mengukur indeks keragaman, dominasi, menganalisis toksoplasmosis pada tikus dan peranannya pada penularan toksoplasmosis di Kabupaten Banjarnegara. Jenis penelitian deskriptif dengan pengambilan sampel secara purposive. Survei tikus dilakukan dengan metode single live trap di pasar induk, rumah sakit umum dan kompleks pertokoan Kelurahan Semampir. Pemeriksaan toksoplasmosis menggunakan FELISA imunostik. Angka keberhasilan penangkapan tikus rata-rata sebesar 7,63% dengan keberhasilan penangkapan tertinggi pada pasar induk sebesar 17%. Spesies tikus tertangkap adalah Rattus tanezumi dan Rattus norvegicus, dengan dominasi R. tanezumi sebesar 98,32%. Mayoritas tikus betina yang tertangkap. Indeks keragaman spesies tikus di tempat-tempat umum rendah (<1). Toksoplasmosis pada tikus sebesar 3,57% menunjukkan bahwa tikus kurang berperan dalam penularan toksoplasmosis di Banjarnegara.
TEORIA HISTÓRICO-CRÍTICA: O CAMINHO PARA UMA EDUCAÇÃO PROFISSIONAL E TECNOLÓGICA EMANCIPADORA
Authors: Sá Filho Paulo de , Gonçalves Mendes Lima Cláudia Caetano , Silva Santiago Léia Adriana da , Antônio de Carvalho Marco 
Published: December 2018

No campo da educação há diversas teorias pedagógicas, as quais podem ter um caráter reprodutor ou transformador. Por exemplo, a teoria Histórico-Crítica, fundamento desse estudo, possui uma natureza emancipadora, portanto se propõe a romper com o modelo reprodutivista e hegemônico das teorias tradicionais. Essa teoria, segundo Demerval Saviani (2013b), possui como aspecto central um viés transformador e surge como um possível caminho para o aperfeiçoamento das práticas educativas no sistema educacional, em especial a Educação Profissional e Tecnológica - EPT, tendo como foco a formação omnilateral dos indivíduos, ou seja, sua capacitação profissional e desenvolvimento de senso crítico quanto à cidadania. Assim, essa pesquisa visa compreender como uma teoria pedagógica de caráter democrático pode contribuir para o processo formativo na EPT, sob a ótica da formação integral. Para constatar isso, utilizamos como método de pesquisa a revisão bibliográfica, observando a prática educativa em três pilares: o pleno desenvolvimento da pessoa, concepção omnilateral; seu preparo para o exercício da cidadania, visão emancipatória; e sua qualificação para o trabalho, que vislumbra a atividade profissional como princípio educativo.