bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prolonged Elevated Heart Rate and 90-Day Survival in Acutely Ill Patients: Data From the MIMIC-III Database
Authors: Sandfort Veit , Johnson Alistair E.W. , Kunz Lauren M. , Vargas Jose D. , Rosing Douglas R. 
Published: February 2018

Purpose: We sought to evaluate the association of prolonged elevated heart rate (peHR) with survival in acutely ill patients. Methods: We used a large observational intensive care unit (ICU) database (Multiparameter Intelligent Monitoring in Intensive Care III [MIMIC-III]), where frequent heart rate measurements were available. The peHR was defined as a heart rate >100 beats/min in 11 of 12 consecutive hours. The outcome was survival status at 90 days. We collected heart rates, disease severity (simplified acute physiology scores [SAPS II]), comorbidities (Charlson scores), and International Classification of Diseases (ICD) diagnosis information in 31 513 patients from the MIMIC-III ICU database. Propensity score (PS) methods followed by inverse probability weighting based on the PS was used to balance the 2 groups (the presence/absence of peHR). Multivariable weighted logistic regression was used to assess for association of peHR with the outcome survival at 90 days adjusting for additional covariates. Results: The mean age was 64 years, and the most frequent main disease category was circulatory disease (41%). The mean SAPS II score was 35, and the mean Charlson comorbidity score was 2.3. Overall survival of the cohort at 90 days was 82%. Adjusted logistic regression showed a significantly increased risk of death within 90 days in patients with an episode of peHR ( P < .001; odds ratio for death 1.79; confidence interval, 1.69-1.88). This finding was independent of median heart rate. Conclusion: We found a significant association of peHR with decreased survival in a large and heterogenous cohort of ICU patients.
Enhanced inpatient rounds, appointment reminders, and patient education improved HIV care engagement following hospital discharge
Authors: Khawcharoenporn Thana , Damronglerd Pansachee , Chunloy Krongtip , Sha Beverly E 
Published: February 2018

Human immunodeficiency virus (HIV) care engagement post hospital discharge is often suboptimal. Strategies to improve follow-up are needed. A quasi-experimental study was conducted among hospitalized HIV-infected patients between the period from 1 January 2013 to 30 June 2014 (preintervention period) and 1 July 2014 to 31 December 2015 (intervention period). During the intervention period, an HIV care team consisting of an Infectious Diseases physician, a nurse, a pharmacist, a social worker, and an HIV-infected volunteer made daily inpatient rounds. Prior to discharge, patients received a structured HIV education session and an outpatient appointment was scheduled for them with two telephone reminder calls following discharge. There were 240 HIV-infected patients enrolled (120 in each study period), of which the median age was 37 years (interquartile range [IQR] 28–44 years), 58% were male, 39% were newly diagnosed with HIV infection, 46% were hospitalized because of AIDS-related conditions, and the median CD4 cell count on admission was 158 cells/µl (IQR 72–382 cells/µl). The rate of HIV care engagement within 30 days after discharge was significantly higher in the intervention period compared to the preintervention period (95% versus 69%; P < 0.001). Independent factors associated with no care engagement within 30 days were patients in the preintervention period (adjusted odds ratio [aOR] 6.36; P < 0.001) and new diagnosis of HIV infection (aOR 2.77; P = 0.009). The study findings suggest that enhanced inpatient rounds, appointment reminders, and patient education were shown to be associated with improved HIV care engagement after hospital discharge. Patients with a new diagnosis of HIV infection benefit from more intense outreach. ClinicalTrials.gov Identifier: NCT02578654
Mixing things up: How blocking and mixing affect the processing of codemixed sentences
Authors: Johns Michael A , Valdés Kroff Jorge R , Dussias Paola E 
Published: February 2018

Aims and objectives/purpose/research questions: The goal of this study is to determine if the way in which codemixed sentences are presented during experimental lab sessions affects the way they are processed, and how experimental design approximates (or not) patterns of language use in bilingual populations. Design/methodology/approach: An eye-tracking study was conducted comparing reading times on codemixed and unilingual Spanish sentences across two modes of presentation: (a) a blocked mode, where one block contained unilingual Spanish sentences and another one contained codemixed sentences; and (b) a mixed mode, where both unilingual and codemixed sentences were mixed together in a randomized fashion. Data and analysis: 20 heritage speakers of Spanish were tested. Four reading measures extracted from the eye-tracking data were subjected to linear mixed-effects regression, with significance determined via backwards likelihood ratio tests, to examine differences across modes of presentation. Findings/conclusions: Codemixes took significantly longer to process in the blocked mode than in the mixed mode. This is in line with corpus data suggesting that intra-sentential codemixing does not occur for long stretches of time and is broken up by unilingual discourse. Originality: While a few studies have hinted at the potential confounds related to the presentation of codemixed or language-switching stimuli, the direct effects of experimental manipulation coupled with insights from sociolinguistic or corpus-based studies have not been tested. Significance/implications: To better understand bilingual codemixing, as well as the cost (or lack thereof) associated with it, lab-based studies of codemixing should take insights from sociolinguistic and corpus-based research. The results of this study suggest that the experience that participants bring into the lab can interact with experimental design and result in unexpected results.
Mortality in patients with cardiogenic shock treated with the Impella CP microaxial pump for isolated left ventricular failure
Authors: Sieweke Jan-Thorben , Berliner Dominik , Tongers Jörn , Napp L Christian , Flierl Ulrike , Zauner Florian , Bauersachs Johann , Schäfer Andreas 
Published: February 2018

Aims: Cardiogenic shock is still associated with high mortality rates of around 50%. Intra-aortic counterpulsation had been frequently used in cardiogenic shock, but was previously found to provide no mortality benefit. We investigated the effect of an interdisciplinary and multiprofessional routine strategy of early invasive haemodynamic support in combination with complete revascularization in patients with cardiogenic shock before admission to our intensive care unit. Methods and results: We analysed all cardiogenic shock patients (mean age 62±13 years) presenting at our institution between 2013 and mid 2016, who received an Impella CP microaxial pump for isolated left ventricle support ( n=61). Sixty-one per cent ( n=37) had been resuscitated before Impella insertion. Overall mortality was 48% ( n=29/61) at 30 days. Thirty-day mortality was higher in resuscitated patients (resuscitated: 65% ( n=24/37); non-resuscitated: 21% ( n=5/24)). When applying the inclusion/exclusion criteria of the SHOCK-II trial, eligible patients ( n=25) had a markedly lower mortality (24% ( n=6/25) at 30 days) compared with the published trial (~40% in both arms). The observed mortality of SHOCK-II-like patients in the registry was also lower compared with their predicted mortality using IABP-Shock II score (49%) and CardShock score (36%). Conclusion: The results of this registry suggest that using a standardized protocol including early active haemodynamic support with Impella CP in cardiogenic shock in patients with isolated left ventricle failure may be associated with improved outcomes and lower than previously reported or predicted mortality rates. Pre-implantation cardiac arrest critically influences observed mortality. The results support the case for a randomized trial.
Effect of correcting for gestational age at birth on population prevalence of early childhood undernutrition
Authors: Perumal Nandita , Roth Daniel E. , Perdrizet Johnna , Barros Aluísio J. D. , Santos Iná S. , Matijasevich Alicia , Bassani Diego G. 
Published: February 2018

Abstract
Background
Postmenstrual and/or gestational age-corrected age (CA) is required to apply child growth standards to children born preterm (< 37 weeks gestational age). Yet, CA is rarely used in epidemiologic studies in low- and middle-income countries (LMICs), which may bias population estimates of childhood undernutrition. To evaluate the effect of accounting for GA in the application of growth standards, we used GA-specific standards at birth (INTERGROWTH-21st newborn size standards) in conjunction with CA for preterm-born children in the application of World Health Organization Child Growth Standards postnatally (referred to as ‘CA’ strategy) versus postnatal age for all children, to estimate mean length-for-age (LAZ) and weight-for-age (WAZ) z scores at 0, 3, 12, 24, and 48-months of age in the 2004 Pelotas (Brazil) Birth Cohort.

Results
At birth (n = 4066), mean LAZ was higher and the prevalence of stunting (LAZ < −2) was lower using CA versus postnatal age (mean ± SD): − 0.36 ± 1.19 versus − 0.67 ± 1.32; and 8.3 versus 11.6%, respectively. Odds ratio (OR) and population attributable risk (PAR) of stunting due to preterm birth were attenuated and changed inferences using CA versus postnatal age at birth [OR, 95% confidence interval (CI): 1.32 (95% CI 0.95, 1.82) vs 14.7 (95% CI 11.7, 18.4); PAR 3.1 vs 42.9%]; differences in inferences persisted at 3-months. At 12, 24, and 48-months, preterm birth was associated with stunting, but ORs/PARs remained attenuated using CA compared to postnatal age. Findings were similar for weight-for-age z scores.

Conclusions
Population-based epidemiologic studies in LMICs in which GA is unused or unavailable may overestimate the prevalence of early childhood undernutrition and inflate the fraction of undernutrition attributable to preterm birth.
Economies of scope: context of agriculture, small family farmers and sustainability
Authors: Nayak Amar K. J. R. 
Published: February 2018

AbstractWhat does this article offers? It raises questions on the assumptions of efficiency in agriculture, traces the history of the logic of scale replacing logic of scope, analyses its impact on sustainability and offers a framework to discern technical contradictions of efficiency across different sectors and find a balance for sustainability. It delves with a few basic questions: First, what is the assumption for efficiency in agriculture and food production? Second, how efficiency criterion of dominant players in one leading sector decimates the efficiency wisdom of another sector?Tracing the evolution of theory and practice of ‘economies of scale’during the last three centuries of industrial revolution, the article shows the irony of adoptingeconomies of scaletime and again only to face greater economic recession, market failures, climate changes, food crisis and growing un-sustainability of our ecosystem. Through empirical evidences from small family farmers and farmer producer organizations from across India and based on the findings of eight years of action research on designing sustainable producer organization, the article highlights that ‘economies of scope’ in agriculture is not only more efficient for nutritious food production and climate resilience but also for sustainability of agricultural ecosystems and of overall socio-economic-environment.
Βιβλιοκρισία:O. DELOUIS – A. COUDERC – P. GURAN (επιμ.), Héritages de Byzance en Europe du Sud-Est à l’époque moderne et contemporaine (Mondes Méditerranéens et Balkaniques, no 4), École Française d’Athènes, Αθήνα 2013, 528 σελ. ISBN 978-2- 86958-253-8
Authors: ΚΟΥΤΖΑΚΙΩΤΗΣ Γιώργος 
Published: February 2018

Βιβλιοκρισία:O. DELOUIS – A. COUDERC – P. GURAN (επιμ.), Héritages de Byzance en Europe du Sud-Est à l’époque moderne et contemporaine (Mondes Méditerranéens et Balkaniques, no 4), École Française d’Athènes, Αθήνα 2013, 528 σελ. ISBN 978-2- 86958-253-8
Effect of cilostazol on platelet reactivity among patients with peripheral artery disease on clopidogrel therapy
Authors: Hernandez-Suarez Dagmar F. , Núñez-Medina Hector , Scott Stuart A. , Lopez-Candales Angel , Wiley Jose M. , Garcia Mario J. , Melin Kyle , Nieves-Borrero Karid , Rodriguez-Ruiz Christina , Marshall Lorraine , Duconge Jorge 
Published: February 2018

AbstractBackground:Antiplatelet therapy with clopidogrel is recommended to reduce cardiovascular events in patients with peripheral artery disease (PAD); however, clopidogrel efficacy has not been adequately studied in this patient population. Therefore, we aimed to determine the effects of cilostazol therapy on platelet reactivity among PAD patients on clopidogrel.Methods:We performed a cross-sectional pilot study of 46 Puerto Rican patients diagnosed with PAD. The cohort was divided based on use of clopidogrel and cilostazol (n=24) or clopidogrel alone (n=22). Platelet function was measuredex vivousing the VerifyNow P2Y12 assay. Genomic DNA was extracted from peripheral blood samples using the QIAamp DNA Blood Midi Kit, which was subjected to candidate variant genotyping (CYP2C19,ABCB1,PON1andP2RY12) using TaqMan quantitative polymerase chain reaction assays. All analyses were performed using SAS version 9.4 (SAS Institute).Results:Among all enrolled patients, 18 (39%) had high on-treatment platelet reactivity (HTPR). The mean platelet reactivity was 207±53 (range, 78–325) with higher P2Y12 reaction units in the non-cilostazol group, 224±45 vs. 191±55 on the cilostazol group (p=0.03). No significant differences were observed in the clinical or genetic variables between the two groups. A multiple regression analysis determined that history of diabetes mellitus (p=0.03), use of cilostazol (p=0.03) and hematocrit (p=0.02) were independent predictors of platelet reactivity.Conclusions:In Puerto Rican PAD patients on clopidogrel therapy, history of diabetes mellitus, use of cilostazol and hematocrit are independent predictors of platelet reactivity. Adjunctive cilostazol therapy may enhance clopidogrel efficacy among PAD patients with HTPR.
Sepsis as a model for improving diagnosis
Authors: Graber Mark L. , Patel Monika , Claypool Stephen 
Published: February 2018

Abstract
Diagnostic safety could theoretically be improved by high-level interventions, such as improving clinical reasoning or eliminating system-related defects in care, or by focusing more specifically on a single problem or disease. In this review, we consider how the timely diagnosis of sepsis has evolved and improved as an example of the disease-focused approach. This progress has involved clarifying and revising the definitions of sepsis, efforts to raise awareness, faster and more reliable laboratory tests and a host of practice-level improvements based on health services research findings and recommendations. We conclude that this multi-faceted approach incorporating elements of the ‘learning health system’ model has improved the early recognition and treatment of sepsis, and propose that this model could be productively applied to improve timely diagnosis in other time-sensitive conditions.
Der ganzen Idee von Demokratie zuwider?
Authors: Reich Rob 
Published: February 2018

ZusammenfassungStiftungen sind nur bedingt rechenschaftspflichtig, profitieren von großzügigen Steuervergünstigungen, sind zeitlich unbegrenzt und nur dem Stifterwillen verpflichtet. Insgesamt stellen sie damit eine institutionelle Kuriosität dar, die plutokratische Tendenzen in demokratischen Gesellschaften befördert. Aufgrund ihrer spezifischen Struktur sind sie jedoch auch dazu geeignet, zu einem Experimentierfeld für langfristig angelegte sozialpolitische Innovationen zu werden. Langfristig könnte dies Stiftungen zu mehr demokratischer Legitimität verhelfen.
Recent records of dhole (Cuon alpinus, Pallas 1811) in Uttarakhand, Western Himalaya, India
Authors: Pal Ranjana , Thakur Shagun , Arya Shashank , Bhattacharya Tapajit , Sathyakumar Sambandam 
Published: February 2018

Abstract
Camera trap photographs of solitary individuals of Asiatic wild dog or dholes (Cuon alpinus, Pallas 1811) have been recorded from Kheda Tal area in Uttarkashi district of Uttarakhand. This is the first photographic confirmation of the presence of this species in the Himalayan habitats of Uttarakhand. The presence of dholes here seems to be confined to a relatively small area of unprotected habitats affected by various anthropogenic uses. The population of endangered dhole is rapidly declining especially in Himalayan region. Thus, it is imperative that local stakeholders are aware of their presence, and it is highly recommended that investigations of the ecological parameters of this population are continued.
On a viscous two-fluid channel flow including evaporation
Authors: Socolowsky Jürgen 
Published: February 2018

Abstract
In this contribution a particular plane steady-state channel flow including evaporation effects is investigated from analytical point of view. The channel is assumed to be horizontal. The motion of two heavy viscous immiscible fluids is governed by a free boundary value problem for a coupled system of Navier-Stokes and Stephan equations. The flow domain is unbounded in two directions and the free interface separating partially both liquids is semi-infinite, i.e. infinite in one direction. The free interface begins in some point Q where the half-line Σ
1 separating the two parts of the channel in front of Q ends. Existence and uniqueness of a suitable solution in weighted HÖLDER spaces can be proved for small data (i.e. small fluxes) of the problem.
Being White in Black Spaces: Teaching and Learning at a Predominately Black Institution
Authors: Harrington Timothy E. , Thomas Michael 
Published: February 2018

Abstract
This paper serves as a beginning conversation of how two White males perspectives’ were shaped and how those perspectives evolved while attending and teaching at a Predominately Black Institution (PBI). Their initial understandings of Whiteness are introduced. This is an ethnographic study that utilized personal narratives from a college professor and a doctoral student as they explore Whiteness at a PBI.
Visualizando oportunidades educativas mediante las TIC
Authors: Durán-López Marlene 
Published: February 2018

Las buenas prácticas pedagógicas conllevan a los centros de enseñanza a concebir el tema tecnológico de forma responsable, ética y equitativa. Pensar en la generación de aprendizaje de forma integral conlleva a visualizar la tecnología no como el fin, sino como el medio para lograr los objetivos propuestos. Entender las nuevas tendencias tecnológicas, desde una mirada crítica y pertinente, abre un panorama que se traduce en oportunidades para el crecimiento integral de todos los actores involucrados en el proceso de enseñanza y aprendizaje. Ante este panorama, surge el cuestionamiento tal como lo manifiesta Lévy: ¿Cómo mantener las prácticas pedagógicas de acuerdo con estos nuevos procesos de transacción de conocimiento? Aquí no se trata de utilizar a todo precio las tecnologías sino de acompañar consciente y deliberadamente un cambio de civilización que vuelve a cuestionar profundamente las formas institucionales, las mentalidades y la cultura de los sistemas educativos tradicionales y, sobre todo, los roles del profesor y del alumno (2007, p. 144).Estos nuevos roles se presentan ante los nuevos escenarios tecnológicos, y han de ser concebidos dentro de una estrategia que brinde igualdad de oportunidades y faculte a los actores a mantener la cultura e identidad ante la globalización y las barreras que presenta una sociedad de información ante una sociedad de conocimiento.
Community-Based Tourism in the Citizens 'Territory of the Jalapão (TO): the Experience of Silver Quilombolas Communities e Mumbuca
Authors: De Souza Maria Antônia Valadares , Dos Santos Nayara Silva , Cançado Airton Cardoso 
Published: February 2018

Abstract: this article aims to describe the experience lived by the quilombola communities of Prata and Mumbuca in the implementation of a community based tourism project, both communities belong to the Territory of Jalapão Citizenship in the state of Tocantins. The methodology used in the construction of the work was a talk round, carried out with the actors of the communities involved in the project and participant observation. The operationalization of the tourist routes in the molds that were elaborated was active for a short time. Soon, the community returned to receive tourists of the form that received previously, exploring only the natural beauties. The recognition by the communities themselves of the richness of their cultural identity and natural potential seems to be the most valuable in this experience.O Turismo de Base Comunitária no Território da Cidadania do Jalapão (TO): a Experiência das Comunidades Quilombolas Prata e MumbucaResumo: este artigo tem como objetivo descrever a experiência vivida pelas comunidades quilombolas do Prata e do Mumbuca na implantação de um projeto de turismo de base comunitária, ambas as comunidades pertencem ao Território da Cidadania do Jalapão no estado do Tocantins. A metodologia utilizada na construção do trabalho foi roda de conversa, realizada com os atores das comunidades envolvidas no projeto e a observação participante. A operacionalização dos roteiros turísticos nos moldes que foram elaborados ficou ativa por pouco tempo. Logo, a comunidade voltou a receber turistas da forma que recebia anteriormente, explorando apenas as belezas naturais. O reconhecimento pelas próprias comunidades da riqueza da sua identidade cultural e do potencial natural parece ser o que ficou de maior valor nessa experiência.El Turismo de Base Comunitaria en el Territorio De La Ciudadanía del Jalapão - TO: la Experiencia de las Comunidades Quilombolas Plata y MumbucaResumen: este artículo tiene como objetivo describir la experiencia vivida por las comunidades quilombolas del Plata y del Mumbuca en la implantación de un proyecto de turismo de base comunitaria, ambas comunidades pertenecen al Territorio de la Ciudadanía del Jalapán en el estado de Tocantins. La metodología utilizada en la construcción del trabajo fue rueda de conversación, realizada con los actores de las comunidades involucradas en el proyecto y la observación participante. La operacionalización de los itinerarios turísticos en los moldes que fueron elaborados quedó activa por poco tiempo. Luego, la comunidad volvió a recibir turistas de la forma que recibía anteriormente, explorando sólo las bellezas naturales. El reconocimiento por las propias comunidades de la riqueza de su identidad cultural y del potencial natural parece ser el que ha quedado de mayor valor en esa experiencia.
Atık Su Arıtma Çamuru Uygulamalarının Platanus orientalis (Çınar) Türüne Etkileri
Authors: Çetinkale Demirkan Gülbin , Söğüt Zerrin , Yokaş İbrahim 
Published: February 2018

Bu çalışmada Gökova-Akyaka Atık Su Arıtma Tesisinden
temin edilen arıtma çamurunun, Platanus
orientalis L. (Çınar) türünde, toprağa serilerek kullanımının bitki
gelişimi üzerine etkileri belirlenmiştir. Çalışmada 2 yıl boyunca arıtma çamuru
4 ayda bir ve her uygulamada 20 kg/m2 miktarında verilmiştir. Deneme
3 tekerrürlü olacak şekilde tesadüf parselleri bölünen bölünmüş deneme desenine
göre kurulmuştur. Deneme süresince bitkilerde bitki boyu, gövde çapı ve yaprak
rengi kriterleri incelenmiştir. Denemenin birinci ve ikinci yılları sonunda da
yapraklarda bazı bitki besin elementi ve ağır metal analizleri yapılmıştır. Araştırma
sonucunda P. orientalis türünün artan
arıtma çamuruna rahat tepki verdiği, uygulanan dozların herhangi bir toksik
etkiye sebep olmadığı ve yılda 60 kg/m2 miktarında kullanımının
uygun olacağı belirlenmiştir