bluuebunny/crossref_metadata_2025_split huggingface dataset:
The influence of mineral powders on the resistance of bitumen binder to thermal deformations
Authors: Vysotskaya M. A. , Lesovik V. S. , Katrich Ya. M. , Egorov D. Yu. 
Published: November 2024

Introduction. The complex influence of dynamic loads, climatic factors, and aggressive environments is the driver of premature deformation of asphalt concrete pavements. The main types of failure are: plastic rutting deformations occurring at high temperatures above zero; fatigue cracks in the pavement caused by repeated loads; low-temperature transverse cracks occurring in the area with temperatures below zero while pavement cooling. According to modern concepts, the contribution of the binder to the formation of the described defects reaches 90–100 %. However, bitumen loses its original properties, interacting with mineral powder and forming an asphalt binder, which acts as a binder in asphalt concrete. Therefore, it is advisable to predict the behavior of asphalt concrete in a wide range of temperatures, and especially in low-temperature part, relying not on the bitumen binder, but on the asphalt binder. Materials and methods. Experimental laboratory studies of materials were carried out in accordance with GOST 33133–2014, GOST R 58400.1–2019, GOST 32761–2014, GOST 58401.1–2019, GOST R 58400.8–2019, GOST R 58400.11–2019. The objects of study were bitumen filled with mineral powders from limestone and dust from electric filters of an asphalt concrete plant. Results. Significant changes in the properties of the original bitumen were revealed under the influence of varying degrees of filling with mineral powder from limestone and dust from electric filters. It was shown that filling the binder with mineral powder (dust) in the maximum permissible concentration limit changes the PG (X) brand parameter by three positions from 64 °C to 82 °C. More fundamental data were obtained for the low-temperature stability of samples with a collapse of the parameter (± Y) from -34 °C to -22 °C. By identifying the parameters responsible for low-temperature cracking of the system at the binder level of asphalt, it is possible to scale the knowledge to asphalt concretes.
Análisis del proceso de sucesión en ocho Microempresas Familiares Agropecuarias en el Suelo de Conservación de la Ciudad de México
Authors: Cruz Loaeza Javier , Muñoz Rodríguez Manrrubio , Arvizu Barrón Ezequiel , Salas González José María 
Published: November 2024

El territorio de la Ciudad de México está integrado por Suelo Urbano (SU) y el Suelo de Conservación (SC); este último está destinado a proteger los servicios ecosistémicos de la Ciudad. El SC pierde 0.8 Km2 cada año por el crecimiento urbano provocando problemas ambientales, entre ellos una menor calidad del aire y la baja calidad de agua para uso agropecuario. A pesar de esta problemática, hay familias que han preservado por generaciones sus parcelas en áreas de SC operando Microempresas Familiares Agropecuarias (MEFA ́s). El estudio analizó, a través de estudios caso, el proceso de sucesión familiar en ocho MEFA ́s ubicadas en SC de cinco Alcaldías. Estos estudios se seleccionaron a través de la teoría fundamentada. Los hallazgos reportados remiten al origen de la propiedad tierra donde se ubican las MEFA ́s al año 1880, la más antigua y se ha preservado por identidad productiva y convicción familiar; La G2 dio viabilidad ambiental, economica, social, política y cultural a través de movimientos estratégicos a las MEFA ́s; sin embargo el proceso de sucesión entre G2 y G3 aun no está en los planes de G2, situación que pone en riesgo a las MEFA ́s y al SC.
Influence of the main physiological groups of microorganisms on the bioavailability of 137Cs and its entry from peaty-gley soil into the biomass of Avena sativa L.
Authors: Tankevich E. A. , Nikitin A. N. , Simonchyk Yu. K. 
Published: November 2024

The influence of the main physiological groups of soil microorganisms on transfer of 137Cs from the peaty-gley soil into the biomass of oats (Avena sativa L.) are analyzed in the article. The soil contaminated with radioisotopes after the Chernobyl nuclear power plant accident. The impact of these groups of microorganisms on the content of stable isotopes K, Ca, Sr, Cs in bioavailable forms in the soil are is presented as well. 1 It was established that the introduction of phosphate-mobilizing bacteria and spore-forming ammonifiers into peaty-gley soil did not change the level of 137Cs accumulation in the aboveground biomass of oats. However, both groups of soil microorganisms significantly (by 44‒84 %) increase the content of radioactive and stable isotopes of cesium in water-soluble form in the soil.Against this background, the introduction of phosphate-mobilizing bacteria into peaty-gley soil reduces the accumulation of radionuclide in the roots of the plant by 30.5 %. The absence of increased accumulation of 137Cs in oats with increase in the content of radionuclide in water-soluble form is explained primarily by an increase in the content of К in bioavailable form in peaty-gley soil when phosphate-mobilizing bacteria and spore-forming ammonifiers are added to it.
Conservation significance of the genetic structure of regressive populations of Lobelia dortmanna L. in Belarus
Authors: Mialik A. M. , Hudnaya N. U. , Kulahina T. G. , Dubar D. A. , Titok V. V. 
Published: November 2024

The article analyzes the genetic diversity of populations of Lobelia dortmanna L. (Dortmann’s lobelia) performed using molecular iPBS markers. All known populations in Belarus from lakes Beloye (Luninetsky district), Svityaz (Novogrudsky district), Belyanets and Bredno (Rossonosky district), located in island localities far from the south-east border of the range, were studied. The research results showed that Nei’s greatest genetic distance is characteristic of the Belyanets population (0.15), and the least one is characteristic of the Bredno population (0.10). For this species, no relationship has been identified between the position of the population within the range, its size, plant vitality and the level of genetic diversity.For Belarusian populations of Lobelia dortmanna L., a predominance of interpopulation variability (54 %) over intrapopulation variability (46 %) was established, which indicates a high level of their genetic differentiation. The gene flow for populations of the species under study is 0.35, which confirms the low level of gene exchange between populations and is consistent with an extremely low population size of the species in the territory of Belarus, as well as the isolation of populations both from the main fragment of the species’ range and among themselves. Data of the cluster analysis of Lobelia dortmanna L. populations demonstrate their division into 2 genetically distinct groups, the geographical location of which confirms their genetic connection with the Fennoscandian and Atlantic-European fragments of the species’ range in the northern part of Europe.
Reasons for the existence of the utilitarian approach to literature in Russian writers – supporters of the autonomy of art’s ideas
Authors: Danilovich T. V. 
Published: November 2024

The article is devoted to understanding how Russian writers, who defend the freedom and intrinsic value of art in their literary criticism (А. Fet, A. Druzhinin, N. Minsky, D. Merezhkovsky, V. Bryusov, A. Blok, Ellis, D. Burliuk, Tsvetaeva, Zamyatin, A. Voronsky, L. Lunts, V. Nabokov, N. Ulyanov, E. Kropivnitsky, A. Sinyavsky, S. Dovlatov), interpret the reasons for the utilitarian approach to literature. It is shown that the designated artists in words reveal a wide range of motives for a pragmatic view of artistic creativity. The heterogeneity of these motives is noted from the point of view of the utilitarian writer’s goal, external circumstances, object of influence, and the degree of independence in choosing the pragmatic path in literature. Specific national arguments in favor of utilitarianism considered by apologists for the idea of self­sufficiency and independence of art are highlighted. The motives of the activity of the utilitarian writers which evoke sympathy and respect among a number of representatives of Russian literature who defend the autonomy of art are outlined. The existence of such situations in public life is indicated, which supporters of freedom and the intrinsic value of art consider as conditions justifying and even making necessary the choice of a utilitarian approach to literature and literary criticism.
KARAKTERISTIK KRIM KULIT DENGAN PENGAYAAN MIKROALGA Chlorella sp.
Authors: Wattimena Martha L. , Nanlohy Esterlina E. E. M. , Kaya Adrianus O. W. , Wenno Max R. , Silawane Nurdila 
Published: November 2024

Mikraloga dalam bidang kosmetik dapat digunakan untuk perawatan kulit yang berperan sebagai antioksidan, pelembab kulit, dan melindung kulit dari matahari. Krim atau lotion merupakan salah satu pelembab yang berfungsi meningkatkan kelembaban dan daya tahan air pada lapisan kulit sehinggadapat melembutkan dan menjaga kehalusan kulit. Jenis Mikroalga yang dapat dimanfaatkan dalam pembuatan krim kulit yakni, mikroalga chlorella sp. Chlorella sp. memiliki kandunga protein, lipid, dan klorofil yang bermanfaat sebagai antioksidan, pelembab serta melindungi kulit dari sinar. Tujuan penelitian adalah untuk mengetahui karakteristik fisiko-kimia dan organoleptik krim kulit dengan penambahan tepung chlorella pada konsentrasi yang berbeda. Metode yang digunakan dalam Penelitian ini adalah, metode percobaan dengan empat perlakuan yaitu 0%, 3%, 6% dan 9%. Hasil penelitian menunjukan bahwa krim kulit dengan Penambahan tepung chlorella 3% memiliki nilai terbaik diantara perlakuan lainnya untuk parameteri fisika, kimia, dan organoleptik
IMPACTO DO CÂNCER NA VIDA DO PACIENTE
Authors: Duarte da Costa Mendes Vera Lucia 
Published: November 2024

Quando uma pessoa recebe um diagnóstico de câncer, muitos pensamentos passam pela cabeça dessa pessoa. Será que vou aguentar, como vai ficar minha família, meu trabalho, e tantas outras preocupações. É fundamental que haja uma comunicação aberta e honesta por parte de toda a equipe multidisciplinar, compartilhando de forma clara e acessível, respondendo as dúvidas do paciente.
A Constructive Proof and Algorithm for the 2D Brouwer Fixed-Point Theorem with Surjective Mapping
Authors: Yang Ruohan 
Published: November 2024

This article investigates the two-dimensional Brouwer Fixed-Point Theorem within the context of a surjective continuous transformation function f(x) . This function can be interpreted as defining a continuous vector field. In this framework, each point in the disk is mapped to another point via a specific vector associated with the continuous transformation, thereby establishing a coherent vector field. This function can be interpreted as defining a continuous vector field. In this framework, the vector field can be decomposed two vector fields. Instead of proving the existence of fixed point directly, the article aim to focus on prove the vector fields always has intersection where at this point, the vector fields has opposite direction and same norm.The paper also provide the programming experiment which further verifies the proof.
Effect of Cryogenic Treatment on Hardness Value and Microstructure of Medium Carbon Steel
Authors: Tsamroh Dewi Izzatus , Dika Johan Wayan , Yazirin Cepi , Sasongko Muhammad Ilman Nur , Prasetiyo Ardianto 
Published: November 2024

Medium carbon steel is a kind of material that is usually used in manufacturing axles, gears and shaft. The application of medium carbon steel to axles, gears and shaft requires high hardness on the surface, but high ductility at the core. The mechanical properties of this material can be improved through a heat treatment process. However, in mass production there is obstacles, which is the uneven hardness on the entire surface, thus, it does not meet the hardness standards set as a commercial product. Therefore, cryogenic treatment was added which aimed to maintain the hardness value of the material after heat treatment. The material used in this research was S45C steel. The heat treatment conducted to increase the hardness of S45C steel was hardening followed by tempering. Hardening was carried out at a temperature of 900 with a holding time of 45 minutes, followed by rapid cooling (quenching) using dromus oil as a medium. Tempering was carried out at 450 for 15 minutes. Cryogenic treatment was carried out at -190 for 1 hour. The research results showed that the highest hardness was obtained in specimens with hardening-quenching treatment followed by cryogenics with a hardness value of 35 HRC (core) and 35.8 HRC (surface). The hardness test results were in line with the microstructure test results., where the microstructure of specimens that had hardening-quenching treatment followed by cryogenics were dominated by pearlite, thus the hardness value were high.
ФОРМУВАННЯ МОТИВАЦІЇ ЮНИХ СПОРТСМЕНІВ ДО ЗАНЯТЬ ПЛАВАННЯМ У ДИСТАНЦІЙНОМУ ТРЕНУВАЛЬНОМУ ПРОЦЕСІ
Authors: СОБКО Ірина , СОБКО Яна , БАЛАМУТОВА Наталія , КУРИЛО Ілля 
Published: November 2024

Мотивація має високу значущість у будь-якій діяльності людини, особливо вона необхідна у спорті, де у дуже стислі строки потрібно досягти найкращого результату в ситуації жорсткої конкуренції з іншими спортсменами та спортивними командами. Мета дослідження дослідити вплив експериментальної методики онлайн-занять з плавання на формування мотивації юних плавців в умовах дистанційного тренувального процесу. Учасники: 13 плавців КЗМС ДЮСШОР водних видів спорту Яни Клочкової (вік 13-14 років) м. Харкова). Експеримент тривав 13 тижнів з квітня по червень 2024. На початку та в кінці експерименту було проведено анкетування в інтерактивній формі за допомогою гугл форми. Методи дослідження: теоретичний аналіз та узагальнення сучасних літературних даних, метод анкетування, методи математичної статистики Результати: розроблено експериментальна методика, для формування зовнішніх та внутрішніх мотивів спортсменів до занять плаванням в умовах дистанційного навчання. Методика онлайн-занять включала в себе: вправи на розвиток фізичних якостей «Сухе плавання», які онлайн проводив тренер та спортсмени з впровадженням педагогічного підходу «Я-тренер», теоретичні заняття, онлайн зустрічі з відомими плавцями, перегляд відео та розважальні ігри. Підібрано твердження для анкети-опитувача які дозволяють виявити ставлення плавців до оновленої методики онлайн-тренувань. Виявлено, що результати більшості відповідей на твердження анкети, досліджуваної групи спортсменів, достовірно відрізняються в кінці експерименту (p<0,05; p<0,01). Висновки: розроблено та впроваджено в навчально-тренувальний процес юних плавців методику онлайн-занять з плавання, яка включала в себе поєднання тренувальних онлайн-занять на розвиток фізичних якостей з впровадженням педагогічного підходу «Я-тренер», переглядом відео виступів відомих плавців та розважальних ігор, показано ефективність використання теоретичної та практичної підготовки спортсменів
Somatopsychogenic manifestations of nephroptosis
Authors: Baulina O. A. , Antropov A. Yu. , Gulyaev A. A. , Baulin A. A. , Baulin V. A. , Averyanova L. A. 
Published: November 2024

Introduction. Nephroptosis, another name for the disease is «wandering kidney», means the prolapse of an organ that can move most often in the lower direction on its side along the retroperitoneal space of the abdomen and even reach the pelvis.The purpose of the study: to substantiate the need for new diagnostic research methods using the given clinical examples.Materials and methods. We observed 448 patients with nephroptosis, of whom 132 were operated on using various techniques. We studied the symptoms, paying special attention to somatopsychic abnormalities.Results. A reference on the pathology of the kidneys – nephroptosis is given, special attention is paid to the incomplete study of clinical manifestations, their connection with functional changes in impaired hemo- and urodynamics, to somatopsychic deviations that are formed in the course of the disease. Vivid clinical examples are given, attention is drawn to the fact that in some cases it is possible to correct somatopsychic deviations only by surgery, which neutralizes hemo- and urodynamic disorders.Conclusion. Despite numerous studies regarding the diagnosis and treatment of nephroptosis, new algorithms are needed.
Risk factors for COVID-19 pneumonia in patients with hematological malignancies: a multi-center, prospective study in China
Authors: Li Jun , Chen Ran , Cao Lin , Liu Yi , Zhang Yong , Wei Xia , Liu Zhanshu , Yang Zailiang , Liu Ling , Zhou Meiyu , Xu Guofa , Chen Lanting , Ding Yao , Lei Haike , Liu Lisheng , Yang Zailin , Chen Shuang , Zhang Xiaomei , Tang Yifeng , Fu Huihui , He Sanxiu , Xiao Qing , Xie Xiaoqing , Li Qiying , Nan Yingyu , Li Jieping , Chen Xiaoliang , Liu Yao 
Published: November 2024

PurposeWe aimed to investigate risk factors for COVID-19 pneumonia in patients with hematological malignancies (HM) after Omicron infection.MethodsData from a registered multi-center, prospective, observational study (ChiCTR2300071830) during the latest Omicron BA.5.2 wave in Chongqing, China was used for analysis.ResultsA total of 475 HM patients enrolled in this study. COVID-19 pneumonia was observed in 15.8% (75/475) of patients, with a median age of 58 years (interquartile range [IQR], 48-69 years) and males accounting for 61.3%. Risk factors associated with COVID-19 pneumonia included: 1) Active disease status of HM at infection, with an odds ratio (OR) of 3.42 (95% confidence interval [CI]: 1.59-7.37, P=0.002) compared to complete remission (CR); 2) Incomplete COVID-19 vaccination, 1-2 doses of the vaccine (OR=2.55, 95% CI: 1.28-5.10, P=0.008) or no vaccination (OR=4.81, 95% CI: 2.45-9.43, P&lt;0.001), as opposed to 3 doses (booster); 3) chemotherapy prior to infection, &lt;6 months (OR=2.58, 95% CI: 1.12-5.96, P=0.027) or ≥ 6 months (OR=2.93, 95% CI: 1.31-6.53, P=0.009) compared to no chemotherapy history; 4) NK-cell reduction (&lt; 150/μL) (OR=2.19, 95% CI: 1.27-3.79, P=0.005) versus a normal range of NK cells. During the 6-week follow-up period, 12 patients (2.5%) died, accounting for 16% of COVID-19 pneumonia patients.ConclusionsOur study investigated risk factors for COVID-19 pneumonia in HM patients after Omicron BA.5.2 infection. Highlights that HM patients with these risk factors may be susceptible to lung involvement after Omicron BA.5.2 infection and need to be taken seriously in clinical practice.Clinical Trial Registrationhttps://www.chictr.org.cn/bin/project/edit?pid=195998, identifier ChiCTR2300071830.
Clinically relevant body composition phenotypes are associated with distinct circulating cytokine and metabolomic milieus in epithelial ovarian cancer patients
Authors: Davis Evan W. , Hsiao Hua-Hsin , Barone Nancy , Rosario Spencer , Cannioto Rikki 
Published: November 2024

IntroductionPreclinical evidence suggests that host obesity is associated with tumor progression due to immuno-metabolic dysfunction, but the impact of obesity on immunity and clinical outcomes in patients is poorly understood, with some studies suggesting an obesity paradox. We recently reported that high-adiposity and low-muscle body composition phenotypes are associated with striking increases in epithelial ovarian cancer (EOC) mortality and we observed no evidence of an obesity paradox. However, whether at-risk versus optimal body composition phenotypes are associated with distinct immuno-metabolic milieus remains a fundamental gap in knowledge. Herein, we defined differentially abundant circulating immuno-metabolic biomarkers according to body composition phenotypes in EOC.MethodsMuscle and adiposity cross-sectional area (cm2) was assessed using CT images from 200 EOC patients in The Body Composition and Epithelial Ovarian Cancer Survival Study at Roswell Park. Adiposity was dichotomized as low versus high; patients with skeletal muscle index (SMI) &lt;38.5 (muscle cm2/height m2) were classified as low SMI (sarcopenia). Joint-exposure phenotypes were categorized as: Fit (normal SMI/low-adiposity), Overweight/Obese (normal SMI/high-adiposity), Sarcopenia/Obese (low SMI/high adiposity), and Sarcopenia/Cachexia (low SMI/low-adiposity). Treatment-naïve serum samples were assessed using Biocrates MxP Quant 500 for targeted metabolomics and commercially available Luminex kits for adipokines and Th1/Th2 cytokines. Limma moderated T-tests were used to identify differentially abundant metabolites and cytokines according to body composition phenotypes.ResultsPatients with ‘risk’ phenotypes had significantly increased abundance of metabolites and cytokines that were unique according to body composition phenotype. Specifically, the metabolites and cytokines in increased abundance in the at-risk phenotypes are implicated in immune suppression and tumor progression. Conversely, increased abundance of lauric acid, IL-1β, and IL-2 in the Fit phenotype was observed, which have been previously implicated in tumor suppression and anti-tumor immunity.ConclusionIn this pilot study, we identified several significantly differentially abundant metabolites according to body composition phenotypes, confirming that clinically significant joint-exposure body composition phenotypes are also biologically distinct. Although we observed evidence that at-risk phenotypes were associated with increased abundance of immuno-metabolic biomarkers indicated in immune suppression, additional confirmatory studies focused on defining the link between body composition and immune cell composition and spatial relationships in the EOC tumor microenvironment are warranted.
Characterizing CD38 expression in terminally differentiated B cells using variable lymphocyte receptor B tetramers
Authors: Nair Arundhati G. , Leon-Ponte Matilde , Kim Vy HD , Sussman Gordon , Ehrhardt Götz R.A. , Grunebaum Eyal 
Published: November 2024

IntroductionCD38 is an ectoenzyme receptor found on hematopoietic cells and its expression is used in the flow cytometric analysis of sub-populations of circulating B cells among peripheral blood mononuclear cells (PBMC) to aid in diagnosing patients with different antibody production defects (AbD). Monoclonal antibodies derived from the sea lamprey Variable Lymphocyte Receptor B (VLRB) are emerging as an alternative to conventional mammalian antibodies. We hypothesized that VLRB MM3 (V-CD38) which specifically recognizes CD38 in a manner correlating with its enzymatic activity could identify terminally differentiated B cells in human PBMC. Here we investigate the ability of V-CD38 as a tool to diagnose patients with diverse immune abnormalities including AbD.MethodsThe expression of CD38 on CD3-CD19+CD27+ plasmablasts and CD3-CD19+IgMhiCD27- transitional B cells in PBMC was analyzed by flow cytometry using V-CD38 and compared with a commercial conventional antibody to CD38 (C-CD38).ResultsA highly significant correlation (p&lt;0.001, r=0.99) between the percentages of plasmablasts recognized by V-CD38 and C-CD38 was observed among 36 healthy controls (HC), 7 patients with AbD and 24 allergic individuals (AI). The use of V-CD38 enabled improved gating of the CD38 expressing cells (CD38+), aiding in the observation that patients with AbD had significantly lower (p=0.002) CD38+ plasmablasts (0.13%±0.13%) than HC (0.52%±0.57%). Only 61.3% of the transitional B cells detected by C-CD38 were also recognized by V-CD38 (r=0.95, p&lt;0.001) among the 67 participants. AI had significantly reduced V-CD38 and C-CD38 transitional cells compared to HC (p=0.026 and p=0.012, respectively).ConclusionsV-CD38 is a novel reagent that can assess B cells in human PBMC.