bluuebunny/crossref_metadata_2025_split huggingface dataset:
A novel surgical method for total nail ablation: Use of triple flap technique
Authors: Aksoy Berna , Aksoy Hasan Mete 
Published: November 2018

<p>Total nail ablation for the treatment of onychodystrophies can be performed by using chemicals, surgical resection or laser ablation of nail matrix.<strong> </strong>A female patient with bilateral severe onychodystrophy as a result of inadvertent previous nail surgeries was treated surgically. Proximal complete nail matrix resection and distal 10 mm wide transverse strip partial nail bed resection were performed. A 5 mm wide transverse strip of nail bed was left intact proximally. Proximal nail matrix defect was closed by using the skin of proximal nail fold. The distal nail bed defect was reconstructed by using triple flap technique which was composed of a main central advancement flap containing ventral toe skin and two side flaps containing nail fold skin. The patient healed without any problem and her nail problem was treated successfully. The cosmetic appearance of her first toes was acceptable. Surgical nail ablation followed by volar skin coverage of dorsal surface of the distal phalanx bone by using triple flap technique is an effective surgical treatment method for the correction of advanced nail plate deformities requiring total nail ablation. </p>
Nevus of Ota associated with intracranial melanoma: Case report and review of the literature
Authors: Krishnan Ravi Shankar , Badgwell Christy , Yoshor Daniel , Orengo Ida 
Published: November 2018

<p>There is a known association between nevus of Ota and melanomas involving the brain parenchyma and/or the meninges. We present the unusual case of a 32-year-old African-American female with a nevus of Ota and a contralateral parenchymal, primary CNS melanoma. We discuss the unique features of this case and provide a brief review of the literature regarding nevi of Ota and associated CNS melanoma. Our patient is a 32 year-old, African-American female with a left-sided nevus of Ota who presented with a three month history of headaches and paresthesias involving her left face and arm. An MRI of the brain revealed a hemorrhagic mass in the right temporal lobe, which, after craniotomy, was determined to be a melanoma. Extensive imaging, ophthamologic examination and full-body skin examination revealed no other foci of melanoma. To our knowlege, this is the only case of a nevus of Ota associated with contralateral parenchymal melanoma in an African-American patient. The association of contralateral parenchymal primary CNS melanoma with nevus of Ota is extremely unusual. Futhermore, despite the association of nevus of Ota with CNS melanoma, the literature does not support routine screening of patients with nevus of Ota for CNS melanoma with imaging modalities. </p>
Applicable quality management tools in a production cycle of a selected company
Authors: Zach Martin 
Published: November 2018

The paper deals with quality control in a Czech manufacturing company, especially at its quality department. The objective is to define the identified production failures, using selected quality management tools, and to determine the causes of technological problems. The following methods and tools were used: cause and effect analysisâ€”Fishbone diagrams (Ishikawa diagrams); Pareto charts, flowcharts and others methods, whose results have been visually displayed. Based on a detail analysis of the production failures, the proposal to eliminate them as well as a draft implementation of the corrective action and its effect on enhancing quality in the production company are presented. The elements such as frequency of controls, adherence to regular inspections and replacement of filters in air conditioning units, cleaning and compliance with the work rules were monitored, as these elements have an impact on product quality and customer satisfaction. The implementation of the corrective actions and the related financial estimate are presented.

Keywords: Quality, production process, quality management tools, quality management, implementation, Pareto diagrams, cause and effect diagrams, safety.
Websites of Slovak sports clubs-Analysis, evaluation and recommendations
Authors: Varmus Michal , Vodak Josef , Ferenc Patrik 
Published: November 2018

The paper analyses the websites of sports teams of most popular Slovak sports. For assessment were established 13 parameters. The evaluation focused on the relationship of the club through the website with fans, sponsors and youth. The results of this analysis shows the shortcomings and common features various clubs, in view of the approach to addressing the issue. This article also shows the difference between the clubs and their approach with regard to the sports sector in which they operate.

Keywords: Web site; Critical Success; Factors; Sport; Marketing
Shareholder value: An analysis of return on assets and equity and their impact on corporate strategic donation using profit margin and turnover
Authors: Arhin Solomon 
Published: November 2018

Return on Assets(ROA) and Return on Equity(ROE) are key performance indicators that the investors of company shares always look at to assess their future earning potentials. Any shareholder who anticipates a decline in return on his assets or equity in the form of shares usually takes proactive step to avoid such an unprecedented, unforeseen and undesired events to happen. From the biblical perspective, in Mathew 25:27, investors put their moneys into the bank to obtain interest. This study focuses on establishing relationship between Return on Asset and Return on Equity using Gross margin and Turnover as a model of Corporate strategic Donation in the selected firms. The population for the study is made up all the companies registered with Security and Exchange Commission database. The study uses sample size of consolidated financial statement of 471 subsidiaries that were registered and reported their financial statement with Security and Exchange database. It is a quantitative study that used IBM SPSS version 21 to analyze the data obtained from the secondary source. The responses received were analyzed through descriptive statistics in the form of percentages, mean score , standard deviation , Simple and Multiple Regression Analysis and ANOVA tests to determine how the various groups within the data collected may have greater or lesser influence on the success of Corporate strategic Donation as discretionary management tool. The research reveal that Corporate strategic Donation does not have adverse impact on the measurement of Return on Asset(ROA,) and Return on Equity(ROE,) as the main dependable variables used in the analysis . While Turnover has positive impact on Corporate Strategic Donations, Profit Margin has negative relationship with Corporate Strategic Donation. The study concluded that emerging firms from the downturn were committed to their communities, but also seeking to generate a bigger impact with their contributions. The study recommends that future researchers can use large sample size to show the relationship between corporate donations and their resultant effect on shareholder returns.
Precious metals market in the new millennium
Authors: Badura Peter , KalusovÃ¡ Lenka , KmeÅ¥koc Miroslav , SedliaÄikovÃ¡ Mariana , VavrovÃ¡ KatarÃ­na 
Published: November 2018

In the ever-changing investment environment it is not easy to find a relatively safe investment option. That is the reason why a large part of investors (respective both, the financial science as well as the financial practice) is increasingly concerned with the benefits and risks of investing into precious metals. The aim of this paper was to find out how the prices of gold, silver, platinum and palladium have been behaving in the last 15 years, from January 2001 to December 2015. The prices of selected precious metals, their cross-correlation and their volatility in the last millennium as well as the relation of precious metals prices to S&P 500 index values have been analyzed. The method of correlation analysis has been used as the main research method. Our findings showed that despite the fact that some of the precious metals seemed to be a good choice as a profitable investment none of them have been a good choice for investment diversification, neither with each other nor with the S&P 500 index that represented the stock market. The precious metals can be easily used as a form of financial investments. Unlike S&P 500 index or some other underlying assets the precious metals (especially gold) are financial instruments that are liquid in any part of the world.
Â© 2016 The Authors. Published by Elsevier B.V.
Peer-review under responsibility of Academic World Research and Education Center.
Keywords: precious metals; S&P 500 index; price correlations; standard deviation; new millennium;
Message from Editor
Authors: Bektas Prof. Dr. Cetin 
Published: November 2018

Dear Readers,
It is the great honor for us to publish seventh volume, second issue of Global Journal of Business, Economics and Management: Current Issues.

Global Journal of Business, Economics and Management: Current Issues is an international, multi- disciplinary, peer-refereed journal which aims to provide a global platform for professionals working in the field of business, economics, management, accounting, marketing, banking and finance and scholars and researchers to share their theoretical, empirical and practical knowledge on current issues in the area of business, economics and management.

The scope of Global Journal of Business, Economics and Management: Current Issues includes; but is not limited to current issues on; Accounting, Advertising Management, Business and Economics, Business Ethics, Business Intelligence, Business Information Systems, Business Law, International Finance, Labor Economics, Labor Relations & Human Resource Management, Law and Economics, Management Information Systems, Business Law, Business Performance Management, Business Statistics, Communications Management, Comparative Economic Systems, Consumer Behavior, Corporate Finance and Governance, Corporate Governance, Cost Management, Management Science, Market Structure and Pricing, Marketing Research and Strategy, Marketing Theory and Applications, Operations Research, Organizational Behavior & Theory, Organizational Communication, Prices, Business Fluctuations, and Cycles, Product Management, Decision Sciences, Development Planning and Policy, Economic Development, Economic Methodology, Economic Policy and so on.
Effectiveness measurement of spectral clustering algorithm
Authors: Kuwil Farag Homed Ali 
Published: November 2018

Abstract

After the Kuwil method was found for applying the spectral clustering algorithm, we need a way to make sure of the results, because in many cases the nature of data is not compatible with the algorithm; also, when the data contain more than three dimensions (3D) the results cannot be displayed on the monitor. So I found two techniques, first, for measuring the strength and effectiveness of S.C.A, such as some comparative relationships that measure the following: Effectiveness of algorithm applying, the strength of every cluster and the effectiveness of data correlation inside every cluster. Secondly, analysis of variance (ANOVA) for S.C.A; this depends on distance variance instead of values variance. I applied the methods above to calculate the strength and effectiveness of S.C.A, and they showed good results, so they can offer more reliability for the outputs of the algorithm. Using these relations and ANOVA for S.C.A help us to measure the data receptivity for applying the algorithm by â€˜Kuwil methodâ€™, so the outputs will be more reliable and that will help to spread the use of this algorithm among researchers, analysts and other users.
Keywords: Spectral clustring, algorithm effectiveness, Kuwil method.
Effects of fixed and roaming CN on MIPv6 networks
Authors: Djassi Papa 
Published: November 2018

Mobile Internet protocol version 6 (MIPv6) is a protocol that allows mobile nodes (MNs) to remain accessible while moving in the IPv6 network, providing users with a form of transparency in spite of the mobility. Mobile networks consist of different nodes such as the MN, correspondent node (CN), home agent (HA), foreign agent or router (FA or FR) and mobile router (MR). One of the vital nodes in a mobile network is CN, a node that communicates with the MN. In the future, in times of need, for instance, during wars, disasters or natural hazards, an MN may require the services of a CN in order to roam. In this paper, we analyse the effect of fixed and roaming CN on MIPv6 networks. The results show that, with a fixed CN, the delay variation performance, end-to-end delay and packet received are better than having a roaming CN in the mobile networks. This requires the attention of researchers, especially when all the communicating nodes (i.e., MN and CN) are roaming in the mobile networks to reduce the delay and packet drop, especially during the handover process.
Keywords: MIPv6, fixed CN, roaming CN, MN, HA and FA.
Performance analysis of software maintenance process using stochastic Petri nets
Authors: Nabeel Muhammad , Anwar Zeeshan , Ahsan Ali 
Published: November 2018

Software maintenance is a time taking activity in the real world. Execution time of software maintenance process may get increased due to interdepartmental communication, thus, increasing the cost and decreasing the performance of the process. We suggested performance evaluation of software maintenance process through the transformation of activity diagram into generalised stochastic Petri nets (GSPN). For this study, execution time and cost of maintenance process are defined as performance measures, and the role-based approach is used to understand the flow of software maintenance activities in a software organisation. Activity diagram is constructed to be transformed into GSPN. We used PIPE2 to analyse the GSPN. PIPE2 calculates average number of tokens on a place in the GSPN, throughput of timed transition and state space analysis. State space involves calculation of the reachability of the GSPN net that shows whether a GSPN holds the property of safeness, boundness and is deadlock free.

Keywords: Generalised stochastic Petri nets (GSPN), GSPN analysis, performance evaluation, performance modelling, software maintenance process, stochastic Petri nets.
Study and identification of short-circuit currents at the complex distribution network SIDER EL Hadjar (ex ArceloMittal-Algerie)
Authors: Hakim Benhamida , Tarek Mesbah 
Published: November 2018

Because of an upcoming modernisation of the electricity distribution network in the SIDER EL HADJAR steel complex, a new calculation of the short-circuit current must be taken into account. The objectives are to determine the precise values of the currents of maximum and minimum fault by each start 225 kV, 63 kV and 15 kV of the distribution network to ensure the reliability of the existing system, and to validate the sizing of the 63 kV bus bar follows the increase of the load of the transformer station P4 by replacing the 70 MVA transformer with a 120 MVA transformer and comparing the results to the old computation. The calculation of short-circuit currents is a key step in qualifying the equipment to withstand the thermal and electromagnetic effects. So, to appreciate the reliability of numerical computation of the currents of short circuits requires modelling and simulations with software NEPLAN V5.
Keywords: Initial short-circuit current, power supply system (SIDER EL HADJAR), IEC 60909-0, peak value of short-circuit current, NEPLA software.
Getting Under The(ir) Skin: Applying Personas and Scenarios with Body-Environment Research for Improved Understanding of Users’ Perspective in Architectural Design
Authors: Doktor Olsen Tvedebrink Tenna , Jelić Andrea 
Published: November 2018

The aim of this paper is to move established positions in architectural design by discussing a more refined user perspective. The motivation is threefold. Firstly, fields like environmental psychology and cognitive science for architecture have in recent years brought novel insights on the embodied nature of human spatial experience, and the extensive effects of the built environment on people’s psychosomatic health and behaviour that are not well-captured by existing building standardization systems. Secondly, while the fast growing trends of user-centred and research-based design in architecture have showed that users’ experience is a valuable source of design knowledge, the methods for incorporating this wealth of new insights in the architectural design process are still underdeveloped. Finally, the example of the newly built psychiatric department in Aabenraa, Denmark, whose interior, despite an international architectural award in 2016, had to be re-designed one year after construction due to poor understanding of the users, indicates existing discrepancies in the current approaches to translating research information in user-centred design.

To address these issues, we discuss the experiences from a new masters’ course in ‘Architecture, Health, and Well-being’ and propose that user-centred methods like ‘personas’ and ‘scenarios’ used in IT, marketing, and product development also have a potential to develop more in-depth research-informed user perspectives. As well as, to help students envision and strengthen the architectural quality of the programming and building design throughout the architectural design process, by supporting a ‘design empathic’ understanding and immersion in user perspectives.
Premedication with intranasal dexmedetomidine decreases barbiturate requirement in pediatric patients sedated for magnetic resonance imaging: a retrospective study
Authors: Uusalo Panu , Lehtinen Mirjam , Löyttyniemi Eliisa , Manner Tuula , Scheinin Mika , Saari Teijo I. 
Published: November 2018

Abstract
Background: Barbiturates are commonly used in ambulatory sedation of pediatric patients. However, use of barbiturates involve risks of respiratory complications. Dexmedetomidine, a highly selective α2-adrenoceptor agonist, is increasingly used for pediatric sedation. Premedication with intranasal (IN) dexmedetomidine offers a non-invasive and efficient possibility to sedate pediatric patients undergoing magnetic resonance imaging (MRI). Our hypothesis was that dexmedetomidine would reduce barbiturate requirements in procedural sedation.

Methods: We included 200 consecutive pediatric patients undergoing MRI, and analyzed their hospital records retrospectively. Half of the patients received 3 μg/kg of IN dexmedetomidine (DEX group) 45-60 min before MRI while the rest received only thiopental (THIO group) for procedural sedation. Sedation was maintained with further intravenous thiopental dosing as needed. Thiopental consumption, heart rate (HR) and peripheral oxygen saturation were recorded.

Results: The cumulative thiopental requirement during MRI was (median and interquartile range [IQR]) 4.4 (2.7-6.0) mg/kg/h in the DEX group and 12.4 (9.8-14.8) mg/kg/h in the THIO group (difference 7.9 mg/kg/h, 95% CI 6.8–8.8, P < 0.001). Lowest measured peripheral oxygen saturation remained slightly higher in the DEX group compared to the THIO group (median nadirs and IQR: 97 (95-97) % and 96 (94-97) %, P < 0.001). Supplemental oxygen was delivered to 33 % of the patients in the THIO group compared to 2 % in the DEX group (P < 0.001). The lowest measured HR (mean and SD) was lower (78 (16) bpm) in the DEX group compared to the THIO group (92 (12) bpm) (P < 0.001).

Conclusion: Premedication with IN dexmedetomidine (3 μg/kg) was associated with markedly reduced thiopental dosage needed for efficient procedural sedation for pediatric MRI.
Synthesis and Anti-Inflammatory Effect of Some More New Fluorinated 3-Substituted Amino/ 3,5-Diamino-1,2,4-Triazine Derivatives as Lamotrigine Analogs
Authors: Makki Mohammed S.T. , Abdel-Rahman Reda M. , Alharbi Abdulrahman Salim 
Published: November 2018

Aim and Objective: It is known that the Lamotrigine drug has anti-inflammatory activity. So it was
the goal to prepare similar compounds containing fluorine atoms (fluorine-substituted 3,5-diamino-6-aryl-
1,2,4-triazines) as Lamotrigine drug analogs to evaluate them as an anti-inflammatory.

Materials and Methods:
The novel fluorine substituted 3,5-diamino-6-aryl-1,2,4-triazines as new Lamotrigine
analogs were prepared via aminolysis and/ or ammonolysis of the corresponding 3-thioxo-6-aryl-1,2,4-triazin-
5-ones in ethanolic media.
</P><P>
Results: All the new targets were deduced upon their elemental analysis and spectral data as well as screened
as anti-inflammatory agents, where we found that the fluorinated systems 15 and 9-11 exhibited high and more
activity.

Conclusion:
Simple routes to synthesize some more novel fluorinated Lamotrigine analogs have been reported.
The new targets exhibited high and moderate anti-inflammatory probes. Presence of both amino and CF3
groups caused high biological activities of these compounds were studied.
MicroRNA in Cervical Carcinogenesis: Window of Therapeutic Potential
Authors: Sharma Shiksha , Vashist Minakshi 
Published: November 2018

Background:Cervical cancer is the second leading malignancy for women. In developing countries, it is becoming a public health trouble in adult women. Persistent cervical infection with high-risk human papillomavirus (HPV) may contribute to the development of cervical cancer. The danger is in the fact that woman with HPV can go unnoticed for years. So, women with early cervical cancer and pre-malignant neoplastic disease show no symptoms, until cancer becomes invasive and grows into the nearby tissue. A large number of females die from the disease each year due to late diagnosis and resistance to conventional treatment. In particular, in advanced tumor stage, low response to chemotherapy results in poor prognosis and recurrence. Therefore, new therapies and indicators are needed to overcome chemo-resistance as well as early diagnosis of cancer. There is a continuous search for prognostic and predictive markers in order to help optimize and personalize treatment for improvement in the outcome of cervical cancer.Recent Findings:Non-coding regulatory RNAs that control gene expression at the posttranscriptional level are seeking the attention of scientists in this area. Certain microRNAs have been located near cancer susceptibility loci that correlate tumorgenesis. Multiple profiling studies have revealed a significant change in miRNA expression in cervical cancer patients. A number of miRNAs have shown a consistent up-regulation or down regulation throughout the different stages of cervical cancer.Conclusion:Investigation of microRNAs involved in carcinogenesis and progression of cervical cancer in tissue-specific manner is opening a window in early diagnosis and therapeutics.</P>