bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Five Fingers Technique Terhadap Tingkat Kecemasan Pasien Kanker Pre Operasi
Authors: Amelia Tiara , Indra Rani Lisa , Rasyid T. Abdur 
Published: December 2024

Terdapat beberapa respon psikologis pasien pre operasi salah satunya adalah kecemasan. Kecemasan dapat diatasi secara non farmakologi salah satunya adalah dengan melakukan five fingers technique dikarenakan dapat merelaksasikan tubuh. Penelitian ini bertujuan untuk mengidentifikasi pengaruh five fingers technique pada pasien kanker pre operasi. Jenis penelitian ini adalah kuantitatif desain Quasy Eksperimental dengan without contol group. Populasi penelitian ini seluruh pasien kanker pre operasi yang dirawat diruang Irna Surgikal ruang Dahlia RSUD Arifin Achmad Provinsi Riau, dengan sampel 15 orang sesuai dengan kriteria inklusi yaitu pasien usia dewasa yang mengidap kanker dan H-1 menjalani pembedahan. Instrumen penelitian yang digunakan kuesioner penilaian kecemasan State Anxiety Inventroy (SAI). Analisis yang digunakan adalah analisis univariat dengan menggunakan uji distribusi frekuensi, tendency central dan bivariat dengan paired t test. Hasil analisis univariat dan bivariat yaitu responden dalam penelitian ini keseluruhan berjenis kelamin perempuan 15 orang, mayoritas tingkat pendidikan terkahir yaitu SD, mayoritas sudah menikah, mayoritas tidak pernah melakukan operasi sebelumnya. dan akan menjalani pembedahan mastektomi serta mayoritas responden kanker dengan stadium III. Hasil analisis bivariat menunjukkan adanya pengaruh five fingers technique terhadap tingkat kecemasan pasien kanker pre operasi dengan nilai P-value 0,000 ≤ α = 0,05. Diharapkan penelitian ini dapat menjadi ilmu bermanfaat untuk menurunkan kecemasan.
Gambaran Tingkat Pengetahuan Ibu Terhadap Pemberian ASI Ekslusif Pada Bayi
Authors: Yulianti Tarisha Rizqy , Amir Yufitriana , Fitri Aminatul 
Published: December 2024

Berat Badan Lahir Rendah (BBLR) merupakan suatu riwayat yang menyebabkan Angka Kematian Bayi (AKB) sangat tinggi. Menurut WHO Berat Badan Lahir Rendah sering terjadi di negara negara berkembang. Berat Badan Lahir Rendah (BBLR) merupakan bayi yang memiliki berat badan lahir < 2500 gram. WHO menyatakan bahwa prevalensi setiap tahunnya ada sekitar 20 juta atau 15,5% bayi lahir dengan riwayat BBLR di dunia, dan di Indonesia ada sebanyak 7.150 orang atau sekitar 35,3% bayi lahir dengan riwayat BBLR. Metode: Penelitian ini menggunakan desai deskrptif sederhana dengan responden sebanyak 76 orang berdasarkan kriteria inkulasi dengan menggunakan teknik accidental sampling. Lokasi penelitian dilakukan di RSUD Arifin Achmad Pekanbaru. Instrument penelitian yang dilakukan adalah kuisioner. Hasil: hasil uji statistik menujukkan bahwa tingkat pengetahuan ibu terhadap pemberian ASI Ekslusif pada bayi BBLR dengan pengetahuan tinggi (31.2%), tingkat pengetahuan sedang (61.0%), tingkat pengetahuan rendah (6.5%). Kesimpulan : sebagian responden memiliki tingkat pengetahuan rendah, dan bekerja sebagai ibu rumah tangga, sehingga ibu hanya tau pengetahuan ASI secara umum
Dynamic evaluation and sensitivity analysis of China’s industrial solid waste management efficiency based on ecological environment cycle perspective
Authors: Guan Xin-ge , Ren Fang-rong , Fan Gao , Zhang Qing-qing , Wu Tao-feng 
Published: December 2024

IntroductionThe recycling and repurposing of industrial solid waste is a crucial element of sustainable development in growing industrialized nations.MethodsAn advanced two-stage Data Envelopment Analysis (DEA) model was employed to assess the effectiveness of solid waste management across all 31 provinces in China throughout the period spanning from 2016 to 2022.ResultsThe research findings suggest the following: (1) The circular economy has shown varying degrees of improvement in efficiency across most regions. (2) The average efficiency of the resource reuse stage is not higher than 0.4, indicating significant room for development that requires serious attention. (3) The western region has a higher average solid waste treatment efficiency of 0.65 compared to 0.53 in the eastern region, while the central region falls at a moderate level. Furthermore, this work employed sensitivity analysis to examine the resilience of regional efficiency research and discovered that the overall findings remain statistically significant. Hence, it is imperative to simultaneously enhance the internal administration of businesses and enhance governmental environmental legislation and regulations, with the aim of attaining the utmost optimization of resource recycling.DiscussionThis paper presents policy suggestions for enhancing the solid waste recycling system within provincial government departments, while also establishing the foundation for the expansion of the solid waste treatment industry, which is necessary to accomplish the goal of “double carbon”.
PLEK2: a potential biomarker for metastasis and prognostic evaluation in uveal melanoma
Authors: Liu Yichong , Wang Haiyue , Zhang Qian , Gao Xiaodi , Ji Yiqing , Zhu Yuanzhang , Zhang Jingjing , Luo Wenjuan 
Published: December 2024

BackgroundUveal melanoma (UVM) is an aggressive tumor known for its high metastatic rate, making it necessary to delineate potential molecules that may promote the development of UVM. PLEK2 has been found to promote the progression and metastasis of some tumors, but its role in UVM has not yet been reported. Through this study, we hope to explore the effect of PLEK2 on the prognosis of UVM patients and to discover the potential functional role and intrinsic mechanism of PLEK2.MethodsThe GEO datasets GSE211763 and GSE149920 were analyzed using GEO2R to identify differentially expressed genes that may be associated with UVM progression and metastasis. A Protein-Protein Interaction Network (PPI) was constructed to identify key molecules. The correlation between PLEK2 expression and overall survival was evaluated via GEPIA2, and clinical characteristics of UVM patients were compared based on PLEK2 levels. PLEK2 expression in UVM cell lines was assessed using the CCLE database and confirmed by qPCR and western blot. A weighted correlation network analysis (WGCNA) was performed, followed by gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analyses. Finally, a search for miRNAs potentially regulating PLEK2 expression was performed using TargetScan, miRWalk, and TarBase databases.ResultsComparative analysis of the GEO datasets unveiled 79 commonly up-regulated genes and 238 commonly down-regulated genes. The PPI network identified 9 hub genes, with PLEK2 significantly linked to reduced overall survival. Clinical comparisons indicated significant differences in cancer status (p = 0.013) and tumor diameter (p = 0.039) between high and low PLEK2 expression groups. Elevated PLEK2 mRNA levels were confirmed in UVM cell lines compared to retinal pigment epithelial cells. PLEK2 was enriched in the calcium signaling pathway and associated with the Wnt/Ca2+ signaling pathway. A total of 21 miRNAs potentially regulating PLEK2 were predicted.ConclusionPLEK2 is upregulated in UVM and correlates with poor patient prognosis, likely influencing the calcium signaling pathway. PLEK2 represents a promising prognostic biomarker and therapeutic target for UVM.
Prevalence and characteristics of participants in Dry January 2024: findings from a general population survey in France
Authors: Lespine Louis-Ferdinand , François Diane , Haesebaert Julie , Delile Jean-Michel , Savy Myriam , Tubiana-Rey Benjamin , Naassila Mickael , de Ternay Julia , Rolland Benjamin 
Published: December 2024

BackgroundDry January is a one-month alcohol abstinence challenge for the general population running since 2013 in the United Kingdom, and 2020 in France. Dry January has gained increasing popularity among the public, but studies assessing the individual characteristics associated with awareness and participation remain sparse.MethodsUsing quota sampling, a representative sample of 5,000 French adults completed an online cross-sectional survey between 8 and 17th January 2024. Chi-square tests and binary logistic regressions were used to explore demographic and alcohol-related characteristics associated with awareness of the Dry January campaign as well as participation.ResultsAmong 4,075 past-year alcohol users, 2,468 (61%) were aware of the “Dry January” campaign, of whom 497 (20%) were participants (12% of all alcohol users). Extrapolated to the entire adult French population, this corresponds to an estimated 4.5 million people participating in the Dry January 2024. Awareness was comparable between genders and across age groups, but was greater among individuals with higher occupational status, and lower among those living in Eastern regions of France. Individuals aware of the campaign were more likely to self-evaluate their drinking as “at risk” and to report high-risk consumption. Participation rates did not differ by gender, occupational status, or region but decreased with age. Compared to non-participants, Dry January participants were more likely to self-identify their drinking as at-risk, to be concerned about health-related effects of alcohol, to be concerned about their control (or lack thereof) over drinking, and to report hazardous use or possible alcohol use disorder. However, no evidence was found for an association between high-risk consumption based on AUDIT-C and participation. Among participants, aiming for reduction (vs. abstinence) and official registration (vs. unofficial participation), were associated with worsened alcohol-related measures.ConclusionThis study indicates a stable level of awareness, but encouraging participation in Dry January in France. The results also confirm that temporary alcohol abstinence campaigns primarily attract high-risk drinkers and individuals reporting harmful consequences related to alcohol.
Water, sanitation, and hygiene in selected health facilities in Ethiopia: risks for healthcare acquired antimicrobial-resistant infections
Authors: Elema Teshome Bekele , Negeri Abebe Aseffa , Verstraete Lavuun , Desta Adey Feleke , Al-Mulla Taha , Goyol Kitka , Baye Kaleab 
Published: December 2024

BackgroundInadequate water, sanitation and hygiene (WASH) in health facilities, and the low adherence to infection control protocols can increase the risk of hospital-acquired (nosocomial) infections (HAIs). The risk for HAIs can increase morbidity, and mortality, health care cost, but also contribute to increased microbial resistance.ObjectivesThe study aimed to assess WASH facilities and practices, and levels of nosocomial pathogens in selected health facilities in Oromia Region and Southern, Nations and Nationalities and Peoples (SNNPs) Region.Materials and methodsAn observational cross-sectional study design was employed to assess the WASH facilities in health care in SNNPs (Bulle and Doyogena) and Oromia (Bidre) regions through interviews and direct observations (n = 26 facilities). Water and surface samples were collected from major hospitals and health centers. A total of 90 surface swabs and 14 water samples were collected identified, characterized and tested for antimicrobial susceptibility. Epi-info was used for data entry and the data was subsequently exported to Stata version 17 for data cleaning and analysis.ResultsWater supply, toilet facilities, and waste management procedures were suboptimal (below the minimum standards of WHO). Only 11/26 of the health facilities had access to water at the time of the survey. The lowest hand-hygiene compliance was for Bidre (4%), followed by Doyogena (14%), and Bulle (36%). Over 70% of the identified bacteria were from four categories: Staphylococcus spp., Bacillus spp., E. coli, and Klebsiella spp. These bacteria also found in high-risk locations including neonatal intensive care units, delivery and surgical rooms. Antimicrobial susceptibility detected in ≥50% of the isolates for penicillin, cefazolin, ampicillin, oxacillin, and cotrimoxazole, and ≥ 50% of the isolates displayed multi-drug resistance.ConclusionInvesting in WASH infrastructures, promotion of handwashing practices, implementing infection prevention and control (IPC) measures and antibiotic stewardship is critical to ensure quality care in these settings. We recommend careful use of higher generation cephalosporins and fluoroquinolones.
Spatial distribution and urban–rural disparity of unmet need for family planning among married/in-union women in Ethiopia: a spatial and decomposition analysis
Authors: Kebede Shimels Derso , Mamo Daniel Niguse , Adem Jibril Bashir , Walle Agmasie Damtew , Tsega Yawkal , Addisu Elsabeth , Tadese Zinabu Bekele , Enyew Ermias Bekele 
Published: December 2024

BackgroundHigh unmet need for family planning combined with other factors, such as high early marriage and teenage pregnancy, increases the risk of developing obstetric fistula and other complications. This study aimed to assess spatial distribution and urban–rural disparities of unmet need for family planning among married/in-union women in Ethiopia.MethodsThe study was conducted on secondary data from a cross-sectional survey that was conducted nationally between September and December 2019 using a two-stage cluster design on a total of 265 enumeration areas. A total weighted sample of 5,349 married/in-union women was included in the analysis. ArcGIS Pro and SaTScan software were used to handle spatial analysis. Finally, multivariable decomposition analysis via a logit model was used to decompose the observed difference in unmet need by the compositional difference and the difference in effects of explanatory variables between places of residence.ResultsSpatial distribution of unmet need for family planning was clustered in Ethiopia with a global Moran's I index value of 0.25 (p-value = 0.004). Accordingly, enumeration areas in West Hararge, Arsi, Bale, Gujji, Borena, Jimma, and East Wellega zones of Oromia region, and Gurage, Hadiya, Silte, Gedio, Sidama, Wolaita, Alaba, and Dawro zones of South Nation and Nationality People region, and the southern part of Zone 3 in Afar region were detected as hotspot areas. The decomposition results revealed that there is a significant disparity in unmet need between urban and rural resident women (0.074, p-value &lt; 0.001). Endowment and coefficient factors accounted for the urban–rural disparity, contributing 68.32% and 31.68%, respectively. Household size, husband’s opinion of family planning, community acceptance of family planning, woman’s age at first sexual intercourse, and the woman's age were key determinants of the urban–rural disparity.ConclusionThe results revealed a significant disparity in the unmet need for family planning based on place of residence, with a clustered spatial distribution across the study area and notable hotspot areas. Thus, targeted interventions should focus on mobilizing resources to high-risk areas and addressing the needs of high-risk groups to reduce the observed variation.
Effects of distiller’s dried grains with solubles on enteric methane emissions in dairy and beef cattle: a meta-analysis
Authors: Malik Muhammad Irfan , Li Jianping , Capucchio Maria Teresa , Hassan Talal , Sun Xuezhao 
Published: December 2024

IntroductionDistiller’s dried grains with solubles (DDGS), a by-product of grain fermentation for ethanol production, are extensively used in livestock feed. Given their nutrient composition, DDGS could potentially influence methane (CH4) emissions, a significant greenhouse gas concern in ruminant production systems. This study utilized a multilevel random-effects meta-analysis to assess the impact of DDGS inclusion in cattle diets on CH4 production and yield.MethodsThe literature search was conducted on 23 July 2024. Studies reporting CH4 emissions and dry matter intake (DMI) in cattle fed DDGS-based diets were identified, and data extraction was performed. The meta-analysis calculated the mean difference (MD) for DMI and CH4 yield and the relative mean difference (RMD) for CH4 production across the selected studies.ResultsA total of k = 25 effect sizes from 10 studies were included in the DMI meta-analysis. DDGS had no significant effect on DMI in dairy or beef cattle (p = 0.770, MD = 0.070, 95% confidence interval [CI] from −0.420 to 0.561). For CH4 production, k = 24 effect sizes from 10 studies were analyzed, revealing no significant effect (p = 0.759, RMD = −1.045, 95% CI: from −8.025 to 5.935). Similarly, the meta-regression model indicated that the diet’s ether extract (EE) had no significant influence (p = 0.815, 95% CI from −1.121 to 1.409) on CH4 production. For CH4 yield, k = 23 effect sizes from 10 studies were included, with results showing no significant effect (p = 0.475, MD = −0.434 g/kg DMI, 95% CI: from −1.673 to 0.805). The regression model for the EE content of the diet also showed no significant impact on CH4 yield (p = 0.311, 95% CI: from −0.366 to 0.122).DiscussionThe findings suggest that the inclusion of DDGS does not significantly affect DMI, enteric CH4 production, or CH4 yield in cattle. Moreover, the EE content in DDGS-containing diets does not significantly influence CH4 outcomes. These results indicate that DDGS can be incorporated into cattle diets without exacerbating CH4 emissions, contributing to sustainable livestock feeding practices.
Preemergent Liverwort Control by Organic Mulching in Containerized Ornamental Production
Authors: Sidhu Manjot Kaur , Chaudhari Sushila , Lopez Roberto G. , Patterson Eric L. , Saha Debalina 
Published: December 2024

Liverwort (Marchantia polymorpha) competes for resources within containers, resulting in a reduction in the quality and market value of ornamentals. Therefore, the objective of this study was (1) to assess the impact of different mulch types, depths, and their moisture-holding-capacity on liverwort control and (2) to quantify if phytotoxicities develop on ornamental plants due to the mulches. The percent water retention of four different organic mulches [rice hull (RH), cocoa hull (CH), pine bark (PB), or red hardwood (HW)] was determined in a laboratory experiment. In a greenhouse experiment, the Hosta plantaginea (Plantain Lily) varieties ‘Curly Fries’ and ‘Pandora’s Box’ were mulched with either RH, HW, CH, or PB at a depth of 0.63, 1.27, 2.54, or 5.08 cm. Liverwort thalli coverage on the container surface was visually estimated bi-weekly, and the fresh weight of the thalli was recorded at the end of the experiment. The results indicated that CH mulch retained the highest amount of moisture (86%). The RH and HW mulches, at depths of 1.27 cm or more, provided excellent (>80%) liverwort control in ‘Curly Fries’. All mulches at depths of 1.27 cm or more showed excellent (100%) liverwort control for ‘Pandora’s Box’. Overall, RH and PB mulches at all depths provided excellent liverwort control and no reduction in the growth of ‘Curly Fries’ and ‘Pandora’s Box’.
NILAI INDEKS RIGOR DAN KARAKTERISTIK KIMIA IKAN LELE (Clarias sp.) BERDASARKAN CARA KEMATIAN
Authors: Suryawinata Aldo , Noor Asikin Andi , Zuraida Ita , Sulistiawati Septiana , Diachanty Seftylia 
Published: December 2024

Catfish (Clarias sp.) is a type of fish that is widely cultivated and sold in the market alive. The method of fish death can affect the characteristics of fish because it plays a major role in the process of starting and ending the rigor mortis phase which contributes to the quality and durability of fish. This study aims to determine the effect of method of death on rigor index values ​​and chemical characteristics of catfish (Clarias sp.) and organoleptic values ​​of catfish (Clarias sp. This study used 2 treatments, namely P1 (fish killed immediately) and P2 (fish left alone). without water for 12 hours), each treatment was repeated 2 times. The test parameters were rigor index, pH, Total Volatile Base (TVB), moisture content and organoleptic values ​​observed in each pre, rigor, and post rigor phase. analyzed using the T test to determine the effect of treatment on the test parameters. The results showed that differences in how to kill fish affected the value of rigor index, Total Volatile Base (TVB), and pH. P2 showed an increase in the value of rigor index, Total Volatile Base (TVB) , and the pH is greater than P1.
Kata kunci: Clarias sp., rigor index, pre rigor , post rigor

Ikan lele (Clarias sp.) merupakan salah satu jenis ikan yang banyak di budidayakan dan dijual di pasar dalam keadaan hidup. Cara kematian ikan dapat mempengaruhi karakteristik ikan karena berperan besar pada proses bermula dan berakhirnya fase rigor mortis yang berkontribusi pada mutu dan daya awet ikan. Penelitian ini bertujuan untuk mengetahui pengaruh cara kematian terhadap nilai indeks rigor, karakteristik kimia pada ikan lele (Clarias sp.) dan nilai organoleptik ikan lele (Clarias sp). Penelitian ini menggunakan 2 perlakuan yaitu P1 (ikan langsung dimatikan) dan P2 (ikan dibiarkan tanpa air selama 12 jam dan dimatikan), setiap perlakuan dilakuan pengulangan 2 kali. Parameter uji terdiri dari indeks rigor, pH, Total Volatile Base (TVB), kadar air dan nilai organoleptik yang diamati pada setiap fase pre, rigor, dan post rigor . Data hasil pengamatan di analisis menggunakan uji T untuk mengetahui pengaruh perlakuan terhadap parameter uji. Hasil penelitian menunjukan bahwa perbedaan cara kematian ikan berpengaruh terhadap nilai indeks rigor, Total Volatile Base (TVB), dan pH. P2 menunjukan peningkatan nilai Indeks rigor, Total Volatile Base (TVB), dan pH lebih besar dari P1.
Kata kunci: Clarias sp., indeks rigor, pre rigor , post rigor