bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of Intralesional Alcohol Injection as Preoperative Treatment of Upper Lip Arteriovenous Malformation
Authors: Kreshanti Prasetyanugraheni , Sudjatmiko Gentur , Anindhawati Nur 
Published: January 2019

Management of vascular malformation remains a major challenge because treatment carries a substantial risk of morbidity and recurrence of the fundamental problem. Intra-lesional 96% alcohol injection as a combination with other treatment modalities has good-to-excellent results. Six-year old female with a 5-year history of arteriovenous malformation on her upper lip underwent intralesional alcohol injection under general anesthesia. Afterward we performed excision of the lesion. During the surgery we used Satinsky intestinal clamp to control the bleeding by compressing the artery. The follow up period was 9 months; there were no complications and no signs of relapse. Aesthetically, the result perceived as acceptable to the parents and other viewers. In cases of arteriovenous malformation involving the lip the technique of injecting alcohol 96% intralesional in conjuct with reducing blood loss by using Satinsky intestinal clamps had an acceptable result aesthetically.
Sidik-Chaula Urethroplasty and the Manset Flap for Non-Glanular Hypospadias Repair
Authors: Sukasah Chaula L , Supit Laureen 
Published: January 2019

Hypospadias present with a wide array of meatal position and curvature. Choosing an operative technique for the different types of hypospadias has been challenging and controversial among the plastic, urologic, and pediatric surgeons. Regardless of the selected techniques, primary hypospadias repair still frequently results in complications requiring further surgery, such as fistula, residual chordee, and stricture. Owing to its practicality, the single stage urethroplasties are more-popular and widely used at present. However, our experience found higher rates of postoperative complications with the one-stage procedure compared to the two-stage for repair of non-glanular hypospadia. This article details the operative techniques of the two-stage Sidik-Chaula urethroplasty, a technique that we have implemented in our institution over two decades. It is applicable for the primary repair of any distal, middle, and proximal hypospadias. We also introduce the Manset Flap, a simple modification to the first stage of urethroplasty, which ease neourethra creation in the second stage. However, due to prior insufficient medical recordkeeping, we are yet unable to produce a quantified rate of success and complications by utilizing this technique. A study is currently being done to produce the numbers.
Squamous Cell Carcinoma Arising From Marjolin’s Ulcer Due To Post Burn Scar: A Case Report
Authors: Atmowirdjo Parintosa , Laidding Sachraswaty 
Published: January 2019

Marjolin’s ulcers are a rare squamour cell carcinomas which develops in non-healing scar tissue. The most frequent predisposing lesion is in a post burn wound, especially after flame burns. Incidence appears to be on the rise and outcome of treatment remains poor. A 51-years old male with burn scar at the posterior left calf since 43 years ago. After burnt, the wound was left to heal spontaneously with minimal treatment. Three years later an unhealing wound emerged on the scar. This wound got bigger, spreaded further, turned into a mass 15 x 8 x 5 cm in size. The tumor was mobile, ulcerative with unprovoked bleeding, malodorous, and painful. Biopsy and imaging concluded a diagnosis of Squamous Cell Carcinoma from Marjolin’s Ulcer, Stage III (T4N0M0). Wide excision was performed 1-2 cm from hiperemis area, neighboring muscles sacri"ced. Frozen section revealed a free-tumor margin and wound covered by split thicknes skin graft. On folllow up, STSG’s “take” was 100%. Four months postoperation, a wound the size of 1 x 1 x 0,5 cm appeared at the distal left posterior calf. Biopsy was performed, result showed granulating tissues with no sign of malignancy. The wound was treated in the outpatient, and healed well. Marjolin Ulcer’s prognosis is not very favorable so it best to prevent at the best first place.
Free Vascularized Dermofat Flap For Contouring Maxilla In Fibrous Dysplasia Patients
Authors: Atmodiwirjo Parintosa , Martina Nungki Ratna 
Published: January 2019

Fibrous dysplasia is a disease that causes bone thinning and growth of lesions in one or more bones and leads to bone weakness and scar formation within the bones. Especially when involving the skull or facial bones, the lesions can cause externally visible deformities. We reported one case of fibrous dysplasia of the maxilla reconstructed in our Plastic Surgery Division of Cipto Mangunkusumo Hospital. Data was taken from the medical and surgery records. In this case, we used the Antero Lateral Thigh (ALT) flap to reconstruct the maxilla and facial contour in 26 years old girl with fibrous dysplasia. After the operation we had daily observation to evaluate the blood flow to the flap and it had satisfactory result without any complication. Ultimately, free vascularized dermofat flap with ALT seems to be suitable for craniofacial contouring surgery, in this case for contouring maxilla. Facial contour could further be improved after secondary reshaping of the healed flaps. This led to nearly perfect long-term facial symmetry in all cases. The ALT proved to be a reliable donor site, providing enough well-vascularized fatty tissue for facial contour augmentation.
Evaluation of Facial Trauma Severity in Cipto Mangunkusumo Hospital Using FISS Scoring System
Authors: Bangun Kristaninta , Kesuma Ayu Diah 
Published: January 2019

Many scoring systems were introduced to search prognostic value in trauma patients. Facial trauma is a special trauma because it can cause many disabilities in facial function. There have been several reports on facial severity scoring system, such as Facial Injury Severity Score (FISS) and Maxillofacial Injury Severity Score (MFISS). Although these scoring systems have been introduced in many journals, they are not yet used by many clinicians because of their unawareness of its beneficiary. In this study, we want to introduce and apply these scoring systems in our maxillofacial data, thus it can be used for documentation system, as a research tool, and have prediction value for prognosis We retrospectively collected data on patients with facial trauma in Cipto Mangunkusumo Hospital in 2009. The data collected were age, gender, etiology, use of helmet, type of fracture and treatment given. Each patient then evaluated by FISS score to obtain their degree of severity. Using FISS score introduced by Bagheri, we found the average FISS score ini this evaluation was 3,37 ± 1,9, with minimum value 1 and maximum value 9. Most patients have FISS score 2 (24,7%). From FISS scoring system, we found that most of maxillofacial trauma in Cipto Mangunkusumo hospital in 2009 was mild trauma. In order to evaluate if FISS scoring system has predictive value for prognosis, a large sample and complete maxillofacial database are needed.
Congenital Hypothyroidism
Authors: Multialam Hisworo , Simandjuntak Robert M. , Hamid Endang D. 
Published: January 2019

We report a case of congenital hypothyroidism seen at the Division of Endocrinology, Medical School, University of North Sumatera/Dr. Pirngadi Hospital. A 13-month ols Batak girl presented witih signs and symptoms of congenital hypothyroidism. On physical examination, umbilical and inguinal hernias were present. Treatment with L -Thyroxme using initial dose 45/µg/day for one month was initiated and after two months the signs and symptoms disappeared. Laboratory finding showed normal T4, but T3 was slightly low. Radiological examination was done to evaluate the bone age. The treatment was continued using the follow-up dose of L-Thyroxine 45µg. Although the treatment has resulted in good outcome, evaluations for the child's growth and development should be continued.
Martyno Liudviko Rėzos lietuviška biblija (1816) – evangelikų liuteronų ir Moravijos bažnyčių solidarumo liudijimas
Authors: Strungytė-Liugienė Inga 
Published: January 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]
Straipsnyje teikiamo tyrimo tikslas yra ištirti Moravijos bažnyčios ir Evangelikų liuteronų bažnyčios narių bendradarbiavimą rengiant ir platinant lietuvišką Bibliją. Dingstį atlikti tyrimą davė Hernhuto (Saksonijos žemė, rytų Vokietija) jungtiniame archyve (Unitätsarchiv) rastas lietuviškos Biblijos, spausdintos 1816 m. Karaliaučiuje Heinricho Degeno spaustuvėje, egzempliorius. Šio egzemplioriaus avantitule paliktas donacinis Christiano Friedricho Cunowo (1751–1829), Moravijos bažnyčios pamokslininko, Karaliaučiaus Brolių asociacijos vadovo įrašas, kuris paskatino sukaupti daugiau žinių apie šį asmenį ir ištirti, kaip jo veikla ir pareigos susijusios su 1810 m. oficialiai įsteigta Karaliaučiaus Biblijos draugija, kurios pagrindinis tikslas – rūpintis lietuviškos Biblijos vertimo, leidybos ir platinimo reikalais.
Knygotyrininkas Nojus Feigelmanas (1918–2002)
Authors: Mozūras Dovydas 
Published: January 2019

[straipsnis ir santrauka lietuvių kalba; santrauka anglų kalba]
Nojus Feigelmanas – bibliografas, bibliotekininkas, daug nuveikęs Lietuvos kultūros istorijai. Tikslinga ir nuosekli su knyga susijusi viso gyvenimo veikla pelnė jam knygotyrininko statusą. Jis gimė Panevėžyje 1918 m. vasario 8 d., 1931–1936 m. mokėsi privačioje Panevėžio žydų gimnazijoje, 1936–1940 m. studijavo geodeziją Vytauto Didžiojo universitete, bet jo baigti nespėjo: prasidėjus Antrajam pasauliniam karui buvo pašauktas į kariuomenę. 1959 m. neakivaizdžiai baigė Vilniaus universiteto Istorijos ir filologijos fakultetą. 1950–1990 m. dirbo Vilniaus universiteto bibliotekoje: pradėjęs bibliografu, daugiau kaip tris dešimtmečius vadovavo Retų spaudinių skyriui. Mirė 2002 m. rugsėjo 7 d. Aškelono mieste Izraelyje, į kurį persikėlė 1990 m. Lietuvos knygotyros raidai itin reikšmingi N. Feigelmano sudaryti spausdintiniai katalogai: „Senoji lietuviška knyga Vilniaus universitete“ (1959), „Lietuvos inkunabulai“ (1975), „Vilniaus universiteto bibliotekos paleotipai“ (2003, paskelbta po mirties, parengta bendraautorių). Jis taip pat yra publikavęs tris dešimtis mokslinių straipsnių, rengęs mokslines parodas, kultūrines laidas televizijoje. Straipsnyje, remiantis naujais archyviniais šaltiniais, atskleidžiamas N. Feigelmano kelias knygotyros link, jo veiklos svarba Lietuvos knygotyros raidai, išskiriami esminiai asmenybės formavimuisi įtakos turėję veiksniai, bibliotekininko profesijos pasirinkimas, atvedęs į knygotyrą, tiriami N. Feigelmano sudaryti katalogai, jo parašyti straipsniai. Daroma išvada, kad nuo pradinėje mokykloje skaitytos Toros, gimnazijoje vykusių knygų parodų ir mugių, mokslinės Vytauto Didžiojo universiteto bibliotekos ir karinių bibliotekėlių iki pat darbo mokslinėje Vilniaus universiteto bibliotekoje ir net emigravus į Izraelį – visą ilgą gyvenimo kelią N. Feigelmaną lydėjo knyga.
Barriers and Stigma Experienced by Gay Fathers and Their Children
Authors: Perrin Ellen C. , Hurley Sean M. , Mattern Kathryn , Flavin Lila , Pinderhughes Ellen E. 
Published: January 2019

BACKGROUND:
Gay men have become fathers in the context of a heterosexual relationship, by adoption, by donating sperm to 1 or 2 lesbian women and subsequently sharing parenting responsibilities, and/or by engaging the services of a surrogate pregnancy carrier. Despite legal, medical, and social advances, gay fathers and their children continue to experience stigma and avoid situations because of fear of stigma. Increasing evidence reveals that stigma is associated with reduced well-being of children and adults, including psychiatric symptoms and suicidality.

METHODS:
Men throughout the United States who identified as gay and fathers completed an online survey. Dissemination of the survey was enhanced via a “snowball” method, yielding 732 complete responses from 47 states. The survey asked how the respondent had become a father, whether he had encountered barriers, and whether he and his child(ren) had experienced stigma in various social contexts.

RESULTS:
Gay men are increasingly becoming fathers via adoption and with assistance of an unrelated pregnancy carrier. Their pathways to fatherhood vary with socioeconomic class and the extent of legal protections in their state. Respondents reported barriers to becoming a father and stigma associated with fatherhood in multiple social contexts, most often in religious institutions. Fewer barriers and less stigma were experienced by fathers living in states with more legal protections.

CONCLUSIONS:
Despite growing acceptance of parenting by same-gender adults, barriers and stigma persist. States’ legal and social protections for lesbian and gay individuals and families appear to be effective in reducing experiences of stigma for gay fathers.
PERUBAHAN KONDISI DANAU LIMBOTO YANG TERDETEKSI DENGAN TEKNOLOGI PENGINDERAAN JAUH
Authors: Julzarika Atriyon , Dewi Esthi Kurnia 
Published: January 2019

Saat ini data penginderaan jauh sudah mengalami perkembangan yang pesat, baik dalam aspek sensor, wahana, maupun spesifikasi resolusinya. Data penginderaan jauh dapat digunakan untuk mengidentifikasi sumber daya alam dan lingkungan. Penelitian ini bertujuan untuk mengidentifikasi perubahan kondisi Danau Limboto yang Terdeteksi dengan Teknologi Penginderaan Jauh. Sumber daya perairan danau ini berupa kualitas air, luas permukaan, dan vegetasi air. Data yang digunakan adalah Landsat. Data tersebut digunakan untuk mengetahui perubahan danau secara visual serta perhitungan kualitas air, luas permukaan, dan vegetasi air (hidrofit)nya. Pada penelitian ini, kualitas air hanya difokuskan pada parameter TSS dan kecerahan. Kedua parameter ini bisa diekstraksi dengan metode e-SMART. Metode ini menggunakan band inframerah dekat pada citra Landsat. Hasil yang diperoleh adalah informasi spasial kualitas air, luas permukaan danau, dan vegetasi air di danau Limboto. Hasil ekstraksi kualitas air ini dilakukan uji dengan data lapangan. Uji akurasi menggunakan metode geostatistik non parameter (uji Fischer). Hasil uji akurasi yang diperoleh adalah95 % pada tingkat kepercayaan 1,96 σ. Uji akurasi dilakukan dengan membanding hasil pengukuran di citra dengan data lapangan. Hasil penelitian ini diharapkan bisa digunakan juga untuk membantu kegiatan nasional serupa, yaitu pemantauan 15 danau prioritas di Indonesia.
KONDISI PADANG LAMUN DI PERAIRAN TIMUR INDONESIA (THE CONDITION OF SEAGRASS MEADOW IN THE WATERS OF EASTERN INDONESIA)
Authors: Supriyadi Indarto Happy 
Published: January 2019

ABSTRAKPadang lamun memiliki peran penting dalam suatu ekosistem perairan dangkal (mangrove, lamun dan terumbu karang). Namun kegiatan pembangunan di wilayah pesisir yang terus meningkat telah mengakibatkan kerusakan padang lamun yang hampir terjadi di seluruh perairan Indonesia. Saat ini informasi terkait dengan keanekaragaman spesies, kondisi lamun, dan luasannya khususnya di perairan timur Indonesia masih kurang. Tujuan penelitian ini yaitu memberikan informasi keanekaragaman spesies, kondisi padang lamun dan luasannya. Metode yang digunakan yaitu mengumpulkan data primer hasil kajian sejak 2005-2016 serta data sekunder dari beberapa sumber data hasil pemantauan kesehatan terumbu karang dan ekosistem terkait (lamun) pada program pemulihan dan pengelolaan terumbu karang (Coremap)-CTI 2015-2016. Identifikasi spesies lamun berdasarkan pada McKenzie (2003), pengambilan data dan analisa kondisi lamun mengacu pada buku panduan pemantauan padang lamun dan berdasarkan KMNLH (2004) no. 200. Hasil identifikasi spesies lamun ditemukan 10 dari 12 spesies lamun yang ada di perairan Indonesia. Kondisi padang lamun di perairan timur Indonesia dikategorikan‘baik’ (43%),’sedang’ (50%) dan ‘jelek’ (7 %) dengan luas padang lamun saat ini yaitu 146.283,68 ha. ABSTRACTSeagrass meadows has an important role at the shallow waters ecosystems (mangrove, seagrass and Coral reef). Development activities in the coastal area which is on still the rise has resulted in damage of the seagrass meadow in Indonesia waters. Current information related to biodiversity of seagrass, condition and extent of area in the eastern waters of Indonesia is still lacking. The goal of the research is to provide information about biodiversity, condition of seagrass meadows and extent of seagrass. The methods used the primary data collection of the result of study since 2005-2016 and secondary data collection from the Reef Health Monitoring and related ecosystem (seagrass) activity in the Coral reef Management and Rehabilitation Programme (Coremap)-CTI 2015-2016. Seagrass identification based on McKenzie (2003), collection of data and analyze of seagrass condition refer to the guide book monitoring of seagrass and KMNLH (2004) no.200. The Results of the study is found 10 of the 12 species of seagrass have found in the Indonesia waters. The condition of seagrass meadows are generally 'good’ (43%), ‘medium’ (50%) and 'poor’ (7%). Extent of seagrass area currently is 146,283.68 ha.
Neurostructural correlates of strength decrease following total knee arthroplasty: A systematic review of the literature with meta-analysis
Authors: Paravlic Armin H , Kovač Simon , Pisot Rado , Marusic Uros 
Published: January 2019

Recent literature suggests that alterations in both neural and structural components of the neuromuscular system are major determinants of knee extensor muscle weakness after total knee arthroplasty (TKA). Therefore, the goal of this study was to investigate the maximal voluntary strength (MVS), voluntary muscle activation (VMA), and the cross-sectional area (CSA) of the muscle, up to 33 months after the TKA. We searched relevant scientific databases and literature for outcomes of interest, including quadriceps MVS, VMA, and CSA. Ten studies met the inclusion criteria and involved a total of 289 patients. The quality of the studies was evaluated by Methodological Index for Non-Randomized Studies (MINORS). Results showed that quadriceps MVS markedly declines in the early postoperative period, after which it slowly and linearly recovers over time. However, the same phenomenon was not observed for VMA and CSA, which were not significantly altered after the TKA. Furthermore, a meta-regression analysis revealed that the change in VMA accounted for 39% of the relative change in quadriceps strength (R2=0.39; p=0.015) in the early postoperative period. Patients treated with TKA had considerable weakness of the quadriceps muscle, which was detectable up to 3 months after surgery. Although the change in VMA largely explains quadriceps weakness, this change and CSA differences were not significant, suggesting that other neural correlates, such as hamstrings coactivation, might alter quadriceps muscle function. Thus, more attention should be paid to address VMA failure and coactivation of antagonist muscles. More comprehensive rehabilitation approaches may be required to target the whole neural circuit controlling the motor action.
Efficacy and safety of nivolumab in the treatment of relapsed/refractory classical Hodgkin’s lymphoma: Pavlov First Saint Petersburg State Medical University experience
Authors: Lepik K. V. , Mikhailova N. V. , Kondakova E. V. , Tsvetkova L. A. , Zalyalov Yu. R. , Borzenkova E. S. , Moiseev I. S. , Baykov V. V. , Afanasyev B. A. 
Published: January 2019

Background . Using modern first-line chemotherapy more than 80 % of patients with classical Hodgkin’s lymphoma can be cured, however, in 15–20 % of cases there is a relapsed/refractory disease. The use of nivolumab in international clinical practice has significantly improved treatment results of patients with relapsed/refractory classical Hodgkin’s lymphoma.Objective of this study is to evaluate the results of therapy with nivolumab in the сlinic of Pavlov First Saint Petersburg State Medical University.Materials and methods . The retrospective analysis included treatment results of 101 patients with relapsed/refractory classical Hodgkin’s lymphoma who received nivolumab in Raisa Gorbacheva Memorial Research Institute of Children Oncology, Hematology and Transplantation from February 2016 to August 2018. The group included 90 patients who received nivolumab as part of an named patient program. Therapy response was assessed using CT/PET-CT in accordance with LYRIC criteria for response assessment of malignant lymphomas to immunotherapy. Safety and tolerability were assessed by registering adverse events in accordance with NCI CTCAE version 4.03 criteria. Results . Median follow-up was 25 months. The response was registered in 64 % of patients: in 32 (31.6 %) – complete response and in 33 (32.7 %) – partial response. Stabilization and progression as the best response were registered in 5 (4.9 %) and 10 (9.8 %) patients, respectively. Indeterminate response was observed in 21 (20.6 %) patients. The 2-year overall survival was 96 %; the median of overall survival was not achieved. Progression-free survival (PFS) in studied patients was 40.6 %. The median of PFS was 17.9 months. There were no significant differences in PFS between patients with a partial and indeterminate response. Adverse events were reported in 87.1 % of patients. Severe adverse events (III–IV grade) occur in 18.8 % of patients.Conclusion . The results of a retrospective study of nivolumab therapy in Russian patients with relapsed/refractory classical Hodgkin’s lymphoma are consistent with published international data. Nivolumab demonstrates high efficacy as a monotherapy for relapsed/refractory classical Hodgkin’s lymphoma, regardless of previous therapy type and duration with well tolerance. Pseudo-progression phenomena during immunotherapy require revision of the traditional Hodgkin’s lymphoma therapy response criteria.