bluuebunny/crossref_metadata_2025_split huggingface dataset:
INVESTIGATION OF THE CLINICAL SIGNIFICANCE OF ESCITALOPRAM-INDUCED ELECTROCARDIOGRAPHIC CHANGES IN MEN: A PILOT OBSERVATIONAL STUDY
Authors: Almeman Ahmad Abdulrahman , ALTWIJRI ANAS , ALSAIF EBRAHIM , ALAHMAD RAKAN , ALAHMAD RAKAN , ALYAHYA AZZAM , ALRUWAIS NABIL , ALMOGBEL BASEM , ELDESOKY AKRAM 
Published: April 2019

Objective: We sought to investigate the clinical significance of secondary electrocardiographic (ECG) changes in men after using escitalopram.
Methods: This pilot observational cohort study recruited male patients taking escitalopram for at least 6 mo in Mental Hospital of Qassim. All patients underwent a 12-lead ECG examination. We also measured the heart rate (HR), QTc, and QRS interval. Data on all related medical conditions and medications were recorded.
Results: Fifty-three men were recruited, with a mean age of 37.39±8.39 y: 34.4% and 31.1% of these patients were taking escitalopram for depression and anxiety, respectively. The mean dose of escitalopram was 14.35 mg. Observations showed that 20.9% of the patients taking escitalopram had a fast HR (>100 beats/min [bpm]), indicative of sinus tachycardia, whereas 11.4% of patients had a slow HR (<60 bpm). The mean QT and QTc in patients taking escitalopram were 366.62±28.69 and 398.92±16.15 ms, respectively.
Conclusion: Low doses of escitalopram resulted in minimal clinically significant changes. Thus, patients should be monitored when doses are escalated further.
THE EFFECT OF CAPITAL ALLOCATIONS TO ECONOMIC GROWTH, HUMAN DEVELOPMENT AND POVERTY INDEX PROVINCE IN THE NORTH MALUKU IN YEAR 2010 - 2016
Authors: Umsohy M Iksan 
Published: April 2019

This study aims to test and analyze: 1 Influence of Capital Expenditure Allocation to Economic Growth, 2 Influence of Allocation of Capital Expenditure and Economic Growth to Human Development Index, 3 Influence of Capital Expenditure Allocation, Economic Growth and Human Development Index to Poverty in Districts / Cities in North Maluku Province. The research method used is panel data regression. The results of this research founded that model 1 influence of Capital Expenditure Allocation have significant influence to Economic Growth. Model 2 Capital Expenditure Allocation has a positive but insignificant influence on the Human Development Index even though the increase is not significant while Economic Growth has positive and significant effect on Human Development Index while model 3 allocation of Capital Expenditure has positive and significant influence to Poverty. While Economic Growth has a negative impact on Poverty, Furthermore, Human Development Index (HDI) as an indicator of strengthening of human resources has a negative and significant influence on Poverty level in 9 regencies of North Maluku Province. Keywords: Allocation of Capital Expenditure, Growth, Human Development Index, Poverty
Peningkatan Proses dan Hasil Belajar Mata Pelajaran Matematika Materi Bangun Datar Menggunakan Model Pembelajaran Discovery Learning (DL)
Authors: Puja Nugroho Yehuda , Harjono Nyoto 
Published: April 2019

Artikel ini adalah hasil penelitian tindakan kelas (PTK). Bertujuan untuk memperbaiki proses dan hasil belajar mata pelajaran Matematika siswa kelas 4 SD Marsudirini 78 Salatiga melalui sebuah model pembelajaran Discovery Learning. Mata pelajaran Matematika khususnya materi bangun datar memiliki hasil belajar yang kurang maksimal, demikian pula dengan proses belajar siswa dan kinerja guru yang memperoleh skor rendah dalam pengamatan pra silus. Hal itu terlihat dari perolehan aktivitas guru pra siklus yang memperoleh presentase 67% dan aktivitas siswa pra siklus yang memperoleh 45 % sehingga presentase ketuntasan hasil belajar pra siklus yaitu 35,5%. simpulan hasil penelitianya adalah penerapan model DL dapat meningkatkan proses dan hasil belajar Matematika khususnya materi bangun datar. Terbukti presentase ketercapaian aktivitas guru siklus 1 yaitu 66,5% dan aktivitas siswa 76% kemudian meningkat pada siklus 2 dengan ketercapaian aktivitas guru 76,5% dan aktivitas siswa 83%. Keberhasilan hasil belajar dilihat dari presentase ketuntasan siklus 1 dan siklus 2 yaitu 72,7% meningkat menuju 84%.
Penerapan Pendekatan Kontekstual untuk Meningkatkan Hasil Belajar Matematika
Authors: Luh Rai Ni 
Published: April 2019

Penelitian ini bertujuan untuk meningkatkan hasil belajar matematika siswa kelas I semester I SD Negeri 6 Tianyar melalui penerapan pendekatan pembelajaran kontekstual. Penelitian ini menggunakan pendekatan penelitian tindakan kelas dengan desain siklus model Kemmis dan Taggart. Partisipan yang menjadi subjek penelitian ini adalah siswa kelas I SD Negeri 6 Tianyar yang berjumlah 14 orang. Pembelajaran dilakukan dalam dua siklus tindakan selama dua kali pertemuan. Data dikumpulkan menggunakan metode tes. Data hasil belajar berupa skor selanjutnya dianalisis, dievaluasi, dan direfleksikan. Metode analisis data yang digunakan adalah metode analisis statistik deskriptif. Hasil penelitian menunjukkan bahwa penerapan model pembelajaran kontekstual dapat meningkatkan hasil belajar matematika siswa. Skor hasil belajar pada siklus I menunjukkan rerata 52,14% dan pada akhir siklus I skor hasil belajar menunjukkan rerata 60 Dibandingkan dengan pencapaian skor hasil belajar siklus I, ternyata skor hasil belajar pada siklus II mengalami peningkatan sebesar 65%. Walaupun terjadi peningkatan hasil belajar matematika siswa, namun masih banyak kendala yang muncul selama proses pembelajaran. Berkat keuletan peneliti dan bantuan dari berbagai pihak, berbagai hambatan dan kendala itu dapat di atasi dengan baik sehingga pelaksanaan tindakan dapat berjalan sesuai rencana
Transformasi Representasi Identitas Kepemimpinan Kyai dalam Hubungan Atasan dan Bawahan
Authors: Mundiri Akmal , Bariroh Afidatul 
Published: April 2019

Kharisma yang dimiliki kyai merupakan salah satu power yang dapat menciptakan pengaruh dalam masyarakat. Ada dua dimensi yang perlu diperhatikan, yaitu: Pertama, kharisma yang diperoleh oleh seseorang kyai secara given, seperti postur tubuh besar, suara yang keras dan mata yang tajam serta adanya ikatan genealogis denga kyai kharismaik sebelumnya, Kedua, kharisma yang diperoleh melalui kemampuan dalam penguasaan terhadap pengetahuan keagamaan disertai moralitas dan kepribadian yang saleh, dan kesetiaan menyantuni masyarakat. Dalam dinamika pesantrem, predikat kyai yang berhubungan dengan suatu gelar yang diberikan oleh masyarakat kepada seorang ahli agama Islam yang memiliki ilmu pengetahuan mendalam tentang ajaran agama Islam atau menjadi pemimpin pesantren, kini telah terkontaminasi oleh pengaruh globalisasi yang mampu menghadirkan gejolak atau konflik, baik secara individu maupun kelompok. Dari hasil yang diperoleh, transformasi representasi identitas kepemimpinan kyai dalam hubungan atasan dan bawahan kini mulai terkikis dengan adanya transformasi globalisasi yang masuk ke dalam dunia pesantren. Pergeseran etika dalam hubungan atasan dan bawahan ditunjukkan dengan bentuk transformasi kepemimpinan yang terlihat dengan bagaimana cara kyai menginstruksikan bawahannya dengan tidak menggunakan tangan kanan sebagi penunjuknya. Hal lain juga digambarkan pada tingkah laku seorang kyai dengan semena-mena memerintahkan bawahannya dengan nada suara tinggi sehingga terkesan “makon” dalam bentuk perintah. Kata kunci: Transformasi, representasi identitas, kepemimpinan Kyai
Pengembangan Akhlak pada Pendidikan Anak Usia Dini
Authors: Ayu Sovia Mas , Junaidah Junaidah 
Published: April 2019

Penelitian ini bertujuan mengembangkan akhlak pada Pendidikan anak usia dini yaitu berupa konstruk indikator akhlak. Metode penelitian yang digunakan yaitu Research and Development (R&D) yang dikembangkan oleh Borg & Gall. Validasi konstruk indikator akhlak pada Pendidikan anak usia dini dilakukan oleh pakar Ilmu Pendidikan Anak Usia Dini, dan pakar Pendidikan Islam. Konstruk indikator akhlak pada Pendidikan Anak Usia Dini diujicobakan pada guru PAUD. Penelitian ini menghasilkan konstruk indikator akhlak yang terdiri dari (4) empat aspek, dan empat indikator kesederhanaan, keberanian, kebijaksanaan, dan keadilan. Kata kunci: Akhlak, pendidikan anak usia dini
Manajemen Karakter Peserta Didik melalui Keterampilan Menulis Kritis
Authors: Mahendra Yasinta 
Published: April 2019

Manajemen adalah proses yang dikerjakan untuk mencapai tujuan, baik perorangan maupun organisasi. Sedangkan karakter sendiri bermakna watak, tabiat, atau sifat-sifat kejiwaan yang ada dalam diri seseorang, dapat berasal dari keturunan atau ada faktor lain yang dapat mempengaruhi kakater itu sendiri. Karakter berpengaruh pada model fikiran yang akan dihasilkan seseorang nantinya dalam berfikir dan menentukan sikap. Maka sebaiknya karakter harus di bentuk sejak usia sedini mungkin agar setiap anak terbiasa dengan pola fikir yang positif namun kritis. Kesalahan dalam mendidik anak dapat berakibat pada rendahnya karakter yang dimiliki anak.Menulis adalah penyampaian pesan dengan menggunakan bahasa tulis sebagai medianya. Keterampilan menulis dikuasai hampir sebagian besar orang terutama dalam dunia akademisi, karena kaum akademisi biasnya dikenal dengan istilah kaum intelektual dan identik dengan kritis. Untuk itu ada korelasinya antara menulis kritis dengan manajemen karakter peserta didik, yang diharapkan nantinya pembelajaran menulis kritis ini dapat menguatkan karakter yang ada dalam diri setiap peserta didik. Kata Kunci : Manajemen, Menulis kritis, Karakter
Analisis Tingkat Kepuasan Mahasiswa terhadap Kualitas Jasa (Pelayanan) Akademik Fakultas Tarbiyah dan Keguruan IAIN Raden Intan Lampung
Authors: Hasan Yetri 
Published: April 2019

Pelayanan pendidikan adalah bagian dari berbagai faktor yang ikut menentukan kesuksesan mahasiswa menyelesaikan serangkaian proses akademik secara tepat waktu di sebuah perguruan tinggi. Berbagai keluhan diungkapkan mahasiswa terkait dengan pelayanan akademik, hal ini menjadi alasan penting dan menarik untuk diteliti. Tujuan penelitian ini adalah untuk menentukan capaian kepuasan mahasiswa terhadap pelayanan jasa akademik pada program studi MPI Fakultas Tarbiyah dan Keguruan IAIN raden Intan Lampung. Kualitas pelayanan dalam penelitian ini diukur rmelalui SERVQUAL dengan lima aspek kulitas, yaitu reliability, responsiveness, assurance, empathy dan tangible. Analisis data menggunakan analisis deskriptif dengan mengukur presentase ketercapaian setiap dimensi kualitas pelayanan. Hasil penelitian menunjukkan, pencapaian pada dimensi tangibles sebesar 65%, pencapaian pada dimensi reliability sebesar 73,75%, pencapaian pada dimensi responsiveness sebesar 63%, pencapaian pada dimensi assurance sebesar 68%, dan pencapaian pada dimensi empathy sebesar 68%. Dengan kata lain, tingkat kepuasan pelanggan/mahasiswa, secara umum baru berada pada kategori sedang/cukup. Kata kunci: Kualitas pelayanan, kepuasan mahasiswa, tangible, reliability, responsiveness, assurance, emphaty.
Disciplinary Intervention for Students through Worship
Authors: Dermawan Oki 
Published: April 2019

Discipline is one part of educational character that needs to be instilled to the children since primary school. Application of discipline could deliver through various activities, such as entering the class and when performing congregational prayers, obey the agreement rules and orderly in line up. The purpose of this study is finding out the discipline at Ar Raudhah elementary school, how to apply discipline to the students and what factors are causes of indiscipline in this school. This study uses a descriptive qualitative research approach with observation, interviews and documentation as data collection techniques. Miles and Huberman model is the data analysis technique, three steps include, namely: data reduction, data presentation and verification. While the validity test of the data uses triangulation with the same source but use a different method. The result shows us that students had consistently carried out the worship in schools such as memorizing prayers, hadiths and verses of the Quran, Dhuha, and Zuhr prayers. However, there are some students still need to be motivated furthermore they don't play when performing worship. The most common factor for indiscipline is whenever parents still think that learning is in the classroom activity, later on some of parents leave their children lately. Here we need parental involvement in instilling discipline of the students. Keywords: Discipline in elementary school, Islamic school, worship discipline
Penanaman Karakter Islami Berbasis School Branding di SMPN 3 Slahung Ponorogo
Authors: Arifin Syamsul 
Published: April 2019

Temuan penelitian ini adalah (1) Strategi Penanaman Karakter Islami berbasis School branding di SMPN 3 Slahung Ponorogo adalah melalui nilai religius dan lingkungan adiwiyata. Nilai religius terdiri dari 2 pokok yang pertama kegiatan ibadah dan kedua akhlak. Displin diri dibagi menjadi 4 yaitu disiplin masuk sekolah, disiplin mengikuti pelajaran, displin berpakaian, dan displin bergaul. Sedangkan Lingkungan adiwiyata melalui kegiatan pengelolaan sampah, pengelolaan air limbah, pengelolaan green house, dan pengelolaan kebun buah. School branding adalah memberdayakan lingkungan sekitar menjadi lingkungan adiwiyata serta dalam publikasi kegiatan dan program yang menonjol melalui media elektronik seperti blog, facebook dan koran. Faktor pendukung dan faktor penghambat Penanaman Karakter Islami berbasis School branding di SMPN 3 Slahung Ponorogo adalah faktor pendukung meliputi adanya buku-buku agama, adanya sarana tempat ibadah yang memadai, adanya kegiatan keagamaan, partisipasi yang kompak oleh warga sekolah, dan SMPN 3 Slahung sebagai sekolah yang mampu melakukan school branding dengan sekolah yang religius dan lingkungan adiwiyata. Sedangkan faktor penghambat meliputi waktu yang kurang memadai, kurangnya ilmu keagamaan siswa, dan siswa kurang terbimbingnya agama di rumah dan di masyarakat.
Model of Food Security Software for Evaluation the Food Security Development: Case Study in Bandung City
Authors: Kastaman Roni , Hasanah Insy Alimatun , Pujianto Totok , Mardawati Efri 
Published: April 2019

In order to evaluation the food security development in Bandung, researcher has been conducted in the form of software design to measure the performance of food security development from the aspect of food availability, food accessibility and the utilization and quality of food. The software is created in Microsoft Excel base as an analytics tool. The data used as the material of analysis was taken from the report of the institutions related to the food security development. Data here, is a source for scoring and weghting of the 3 food security dimensions which is filled in the software. List of contents for the analysis of food availability, food access and utilization and quality of food aspect are consist of 27 criteria, 12 criteria and 12 criteria respectively. The evaluation is done based on the calculation of the total value of weight multiplication with the score of each criteria, where the maximum total value is 5000 and minimum 1000. Justification of performance condition of food security performance described in the software is based on 5 categories class, that is from 1000 to 1800 total value performance for “unsafe conditions”, then 1800 to 2600 for “unsafe conditions”, 2600 to 3400 for “fairly safe conditions”, 3400 to 4200 for “safe conditions” and 4200 to 5000 for “very safe conditions”. The result of evaluation by using data in Bandung City of year 2012 and year 2015 indicate that condition of Bandung food security in terms of availability is “fairly safe”, food access is “safe” and the utilization and quality of food is in “fairly safe” condition.
CORRELATION OF FREE HEMOGLOBIN LEVEL AND PLASMA NITRIC OXIDE IN PACKED RED CELL DURING BLOOD BANK STORAGE PERIOD
Authors: Fitria Ricca , Rofinda Zelly Dia , Desywar Desywar 
Published: April 2019

Stored red blood cells undergo morphological and biochemical changes with increased storage time, commonly refferred as the storage lesion, reduced integrity of erythrocyte membrane, causing hemolysis and increased free plasma hemoglobin level. Nitric Oxide (NO) is an endogenous vasodilator with the major role in vascular and blood flow regulation. Accumulation of free hemoglobin (fHb) during storage RBC hemolysis is thought to be correlated with elevated NO consuming causes low NO level that significantly impair endothelial function. This study aim to was to analyze the correlation of free Hb and plasma nitric oxide level during PRC storage period in the blood bank. This research was an analytic study with a cross-sectional design to 14 unit PRC those were stored in Dr. M. Djamil Padang Hospital Blood Bank. The study was conducted from May 2016 to August 2017. The assay was performed for 28 days of storage with one week intervals. Free plasma hemoglobin and NO level were analyzed by cyanmethemoglobin and colorimetry method respectively. Spearman test was used to access the correlation between free Hb level and nitric oxide plasma with p<0.05 means significant. Most donors were male (85.7%) with age range were 33(9) years. Free Hb and nitric oxide level were significantly differenced in each week storage periods (p<0.05). Two parameters was significantly had moderate negative correlation during storage periods (r=-0.56; p=0.01).
THE RELATIONSHIP BETWEEN THE LEVEL OF INTERLEUKIN-6 AND PROCALCITONIN IN SEVERE SEPSIS PATIENTS AT THE ADAM MALIK HOSPITAL
Authors: Nainggolan Sesily C , Aman Adi Koesoema , Hanafie Achsanudin 
Published: April 2019

Severe sepsis is defined as sepsis that is accompanied by one or more organ dysfunctions, hypotension or hypoperfusion (decreased renal function, hypoxemia, lactic acidosis, oliguria, mental status changes). Macrophages and monocytes produced Procalcitonin (PCT) in serious bacterial infections and sepsis. Interleukin-6 (IL-6) is an interleukin that acts as proinflammatory cytokines. The high IL-6 level is due to chronic inflammation and sepsis. IL-6 is found increased more rapidly in the acute phase, so it can be used to evaluate early phase infection and sepsis. The purpose of this study was to find out IL-6 and PCT levels in severe sepsis patients. This study was a cross-sectional observational study. The subjects were sepsis patients treated in Adam Malik Hospital on Jan-Mar 2016. Statistical data was analyzed using SPSS and the Spearman rank correlation, with significant p-value < 0.05. IL-6 was tested using Chem Well 9210 series. Procalcitonin examination was done by mini VIDAS BRAHMS PCT. There were 40 people observed as subjects in this study, 26 males (65%) and 14 females (35%). The average age of male was 49.42 ± 18.19 years old, the youngest 18 years old, and the oldest 79 years old. The average age of females 57.35 ± 20.73, the youngest 18 years old, and the oldest 87 years old. The average of IL-6 was 10862.12 ± 25489.16 and PCT was 9666.73 ± 10540.13. Spearman rank test was also used, the value of r = 0.176 and p = 0.277. The conclusion is there is no significant correlation between IL-6 and PCT. There is no significant correlation between IL-6 and PCT levels in severe sepsis patients.
Torsemide versus furosemide and intermediate-term outcomes in patients with heart failure: an updated meta-analysis
Authors: Miles Jeremy A. , Hanumanthu Balaram K. , Patel Kavisha , Chen Michelle , Siegel Robert M. , Kokkinidis Damianos G. 
Published: April 2019

Aims
Loop diuretics have become a mainstay of chronic heart failure management. Furosemide and torsemide are the two most common loop diuretics; nevertheless, there is inconsistent evidence regarding the optimal choice of loop diuretic with respect to clinical outcomes.

Methods
Medline and Cochrane Databases were systemically reviewed for randomized and observational studies comparing patients with chronic heart failure on oral torsemide versus oral furosemide and their association with intermediate-term outcomes (5–12 months) through May 2018. Odds ratios with corresponding 95% confidence intervals (CIs) were used for outcomes. A random effect model was used to account for heterogeneity among studies. Heterogeneity was assessed with the Higgins I-square statistic.

Results
A total of 8127 patients were included in the analysis from a total of 14 studies (10 randomized, four observational); 5729 patients were prescribed furosemide and 2398 were given torsemide. There was no significant difference in intermediate-term mortality among heart failure patients on furosemide compared with torsemide [odds ratio (OR) 1.01, CI 0.64–1.59, I
2 = 65.8%]; however, furosemide was associated with an increased risk of heart failure readmissions (OR 2.16, CI 1.28–2.64, I
2 = 0.0%). Heart failure patients taking torsemide were more likely to have an improvement in New York Heart Association class compared with those on furosemide (OR 0.73, CI 0.58–0.93, I
2 = 19.6%).

Conclusion
Torsemide is associated with a reduction in intermediate-term heart failure readmissions and improvement in New York Heart Association class compared with furosemide but is not associated with a reduced mortality risk. Additional randomized trials are needed to examine the impact of loop diuretics on clinical outcomes in patients with heart failure.
Prevalence and prognosis of lead masses in patients with cardiac implantable electronic devices without infection
Authors: Golzio Pier Giorgio , Errigo Daniele , Peyracchia Mattia , Gallo Elisa , Frea Simone , Castagno Davide , Budano Carlo , Giustetto Carla , Rinaldi Mauro 
Published: April 2019

Background
Finding of intracardiac lead masses in patients with cardiac implantable electronic devices remains controversial, as such masses have been observed in cases of exclusively local infections whereas they have not been recognized in patients with positive cultures of intravascular lead fragments. In this study, we aim to describe the prevalence of intracardiac lead masses in true asymptomatic patients with cardiac implantable electronic devices, to identify their predictive factors and to define their prognostic impact at long-term follow-up.

Methods
Seventy-eight consecutive patients admitted over a 6-month period for elective generator replacement without clinical evidence of infection were evaluated by transthoracic and transesophageal echocardiography and prospectively followed at in-clinic follow-up visits.

Results
Lead masses were found in 10 patients (12.8%). These patients had more frequently right ventricular dysfunction at univariate analysis (OR 2.71, P = 0.010) and after baseline variables adjustment (hazard ratio 6.25, P = 0.012). At 5-year follow-up without any specific therapy, none of the patients suffered from any cardiac device infections, or developed clinical signs of infections.

Conclusion
There is an evidence of clinical lead masses in asymptomatic patients with cardiac implantable electronic devices. The value of these findings is still debated for aetiological interpretation and for therapeutic strategy, but they are not necessarily associated with an infection.