bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of hMSCs Response to Sodium Alginate / Bioactive Glass Composite Paste: Effect of CaO/P2O5, Sodium Alginate Concentration and P/L Ratios
Authors: Ahmadi Seyed Mohammad , Behnamghader Aliasghar , Asefnejaad Azadeh 
Published: April 2019

Background:
Bioactive glasses with different compositions have been extensively used as
bone tissue engineering. Preparation, development and characterization of alginate pastes containing
bioglass for bone repair applications were the purposes of this study.

Objective:
The injectable bone pastes were produced from sol-gel derived bioactive glass nanoparticles
with various CaO/P2O5 ratios of 19, 9.5 and 4.75 and sodium alginate solutions with different concentrations
of 1, 2 and 4 wt.%. The effect of CaO/P2O5 and powder to liquid (P/L) ratios and alginate concentration
on injectability, biodegradation, rheological properties, bioactivity and cellular behavior of
the pastes have been studied. The behavior of human mesenchymal stem cells (hMSCs) in the presence
of the pastes was assessed by MTT assay, biomineralization assay, ALP activity, Acridine orange
staining and Alizarin red staining tests.

Results:
By adding sodium alginate, the pastes exhibited a thixotropy behavior. The storage modulus
of all pastes was larger than the loss modulus in the frequency range of 0.1-100 s-1. Cytotoxicity
evaluation results revealed that there was a critical amount of bioactive glass in pastes which are above
the limit; the viability of hMSCs will be at risk. The pastes made of bioactive glass nanoparticles with
CaO/P2O5 = 9.5 and sodium alginate 1% with P/L ratio of 0.8 showed optimum behavior in terms of
mineral carrying capacity, injectability characteristics, accellular bioactivity in SBF, loss weight and
wash out behavior, proliferation and differentiation of hMSCs.

Conclusion:
According to the results, the pastes prepared with sodium alginate solution and bioactive
glass nanoparticles can be beneficial in bone tissue engineering.
Amyloid A in Serum and Ascitic Fluid as a Novel Diagnostic Marker of Spontaneous Bacterial Peritonitis
Authors: Badawi Rehab , Asghar Muhammad N. , Abd-Elsalam Sherief , Elshweikh Samah A. , Haydara Tamer , Alnabawy Sherein M. , Elkadeem Mahmoud , ElKhalawany Walaa , Soliman Samah , Elkhouly Reham , Soliman Shimaa , Watany Mona , Khalif Mai , Elfert Asem 
Published: April 2019

Background:
Diagnosis of Spontaneous Bacterial Peritonitis (SBP) depends
mainly on ascetic fluid culture which may be negative in spite of the clinical suggestion of
SBP and high ascetic fluid neutrophilic count.

Aim:
This study aimed to evaluate the biological importance of amyloid A biomarker in
both serum and ascetic fluid to diagnose SBP as early as possible and to compare it to other
markers (C-reactive protein (CRP), and the neutrophil-to-lymphocyte ratio (NLR)).

Methods:
This study included 37 patients with hepatic ascites; twenty-two of them had
SBP, and 15 patients did not have SBP. Serum and ascetic fluid amyloid A, ascetic fluid
neutrophil, C-reactive protein, and neutrophil-to-lymphocyte ratio were measured in all
subjects before the start of antimicrobial chemotherapy to the infected ones.

Results:
Both the serum and ascetic fluid amyloid and also, CRP were significantly higher
in patients infected with ascetic fluid than others. The cut-off point of serum amyloid A for
early detection of SBP was 9.25ug/ml with the high sensitivity and specificity. For ascetic
amyloid A, the sensitivity and specificity were 90.09% and 60% at cut-off point 2.85ug/ml,
respectively.

Conclusion:
Amyloid A in serum and ascitic fluid can be considered as a good biomarker
for early diagnosis of SBP.
Combining Ability and Heterosis for Yield and Related Traits in Chili (Capsicum annuum L.)
Authors: Chakrabarty Swapan , Islam A. K. M. Aminul , Mian M. A. Khaleque , Ahamed Tofayel 
Published: April 2019

Introduction:An experiment was conducted to study combining ability and heterosis for yield and related traits in chili during November 2015 to September 2017.Materials and Methods:The experimental material consisted of six parents and their fifteen F1’s developed by half diallel mating design. Analysis of variance for combining ability exhibited significant General and Specific Combining Ability (GCA and SCA) effects for all the characters studied.Results:The SCA variance was higher than GCA variance for all the traits except ten fresh fruit weight, fruit length and fruit width indicating the predominance of non-additive type of gene action. The parents P1and P6were identified as the best general combiners and the hybrids P1×P6, P1×P4and P2×P5were identified as the best specific combinations for fresh fruit yield per plant and related traits. The hybrids P1×P6, P1×P4and P3×P6showed significant average heterosis and heterobeltiosis for fresh fruit yield per plant and its related traits. (H1/D)0.5ratio indicated partial dominance effect of genes for all the traits.Conclusion:Therefore, it may be possible to take advantages of better heterotic effects to be fixed in the later generations to facilitate further selection and best specific combinations for development of the hybrid variety of chili which can help to increase the total production in Bangladesh.
Influence of Working Memory on Academic Achievement and Quality of Life in Children with Beta-Thalassemia Major
Authors: Gamayani Uni , Meidha Dini Lestari Ni Luh , Ganiem Ahmad Rizal , Panigoro Ramdan 
Published: April 2019

Background:Children with beta-thalassemia major may suffer from working memory impairment. For a more refined understanding of this issue, we assessed working memory function in beta-thalassemia children and evaluated its influence on academic achievement and quality of life.Methods:This was a cross-sectional study involving 60 beta-thalassemia children aged 8-12 years. All participants underwent a working memory assessment using the digit span and were interviewed using academic achievement and Indonesian version of PedsQL 4.0 questionnaires. Working memory in beta-thalassemia children significantly influences their quality of life, both directly (β=0.32) and indirectly, through their academic achievement (β=0.639). Longer duration of transfusion (p=0.01) is significantly related to poorer working memory, while lower hemoglobin level (p=0.81) and higher ferritin level (p=0.24) are not significantly associated with working memory.Conclusion:We concluded that working memory influences the quality of life in beta-thalassemia children, both directly and indirectly, through their academic achievement.
The Role of Phenotypic Personality Traits as Dimensions of Decision-making Styles
Authors: Gulseven Osman , Mostert Jacques 
Published: April 2019

Background:Each individual has unique personality traits which affect decision-making process. Those traits are defined as cautiousness, openness to experience, decision difficulty, agency, emotion neutrality, goal orientation, intuitive awareness, plan orientation, pro-activity, and rationality.Objective:The study aimed to show how established personality traits as dimensions of decision-making can be used to classify four distinct decision-making styles. The personality styles are defined as avoidant, designer, flexible, and auditor styles.Methods:A global survey was conducted to gather information on individual decision-making styles. Quantitative methods, such as tabular analysis, mean score equivalency test, correlation analysis, discriminant analysis and chi-square test for association have been used.Results:We found that there are significant gender differences in personality styles. This is partially due to the differences in emotion-neutrality scores among men and women. Female respondents are more emotional, a finding that is common in educational workers.Conclusion:The results reinforce that gender differences in emotions exist. For a socially interactive occupation such as education, being emotional might lead to better communication.
Prospective of Natural Gum Nanoparticulate Against Cardiovascular Disorders
Authors: Deep Aakash , Rani Neeraj , Kumar Ashok , Nandal Rimmy , Sharma Prabodh C. , Sharma Arun K. 
Published: April 2019

Background:Objective: Various natural gums can be synergistically used in nanoparticulate drug delivery systems to treat cardiovascular diseases. Nanotechnology has been integrated into healthcare in terms of theranostics. In this review, we consider various natural gums that can be used for the preparation of nanoparticles and their role to treat cardiovascular disease.Methods:Nanoparticles can carry drugs at nanoscales and deliver them to the targeted sites with the desired pattern of drug release. They have specialized uptake mechanisms (e.g. - absorptive endocytosis) which improve the bioavailability of drugs.Results:By considering cardiovascular diseases at the molecular level, it is possible to modify the materials with nanotechnology and apply nano-formulations efficiently as compared with conventional preparations, due to the fact that the extracellular matrix (ECM) comprises components at the nanoscale range. The interactions of ECM components with cellular components occur at the nanoscale, therefore the nanomaterials have the potential to maintain the nanoscale properties of cells. The synthetic materials used to develop the nanoparticulate drug delivery system may cause toxicity.Conclusion:This problem can be overcome by using natural polymers. Natural gums can be used in nanoparticulate drug delivery systems as reducing and stabilizing agents and in some cases; they may directly or indirectly influence the rate of drug release and absorption from the preparation.
Experience in the use of modern H-SIL diagnostic methods in the screening of cervical cancer on the example of the Rostov region
Authors: Dimitriadi Tatiana A. , Burtsev Dmitry V. , Dzhenkova Elena A. , Mikhelson Alexander F. , Lebedenko Elizaveta Yu. 
Published: April 2019

Objective: to evaluate the eff ectiveness of the regional cervical cancer screening program by liquid-based cytology. Materials and Methods: the geography of screening includes 54 medical units of the Rostov region, where patients are taken swabs from the cervix. HPV positive patients with abnormal PAP smears are invited to the Regional cervical pathology center for diagnosis and treatment. Methods. liquid-based cytology, the HPV test RealTime PCR, colposcopy with video recording, biopsy of the cervix by the method of loop excision or electroradiographic conization. Results: From 2014 to 2017, 188 641 cytology tests were performed. Cervical cancer was revealed in 189 women – (0.1 %), H-SIL and ASCH in 566 (0.3 %), 377 ASCUS (0.2 %), L-SIL in 23014 (12.2 %), absence of intracellular lesions or malignancy in 164495 (87.2 %). 2162 HPV-positive women aged 18 to 69 years were invited to the Regional cervical pathology center gynecologist for examination. Treatment by conization (622) and excision (830) of the cervix was performed in 1452 patients, H-SIL and CIS were revealed in 1162 women (78 %). Conclusion: tests such as liquid-based cytology and HPV testing, their optimal multiplicity and sequence allow timely detection and treatment of precancerous cervical epithelium lesions.
СРПСКА ПРАВОСЛАВНА ЦРКВА КАО КОМУНИКАЦИОНИ АГЕНС
Authors: Parlic Bozovic Jasna Ljubinko , Божовић Драгана 
Published: April 2019

Since early childbirth, religion has an important function in the life of every human being. Depending on culture, religious norms and values differently are interpreted and deeply embedded into the members of one society through a process of socialization. The way people practice their religion is changing through history. The way individuals relate to and practice a religion changes over the course of time. New technologies have influenced on the appearance of new media - the communication channels, which has also affected the very form of the religious message, that is, how it will be designed, communicated and interpreted.Religion was important for acquiring literacy among the South Slavs. Its word was conveyed verbally as well as throughout printed books, magazines and publication. By the further development of technologies or creating electronic media, the religious message has been received a form adapted to the modern communication channels.It can be said in a revolutionary manner that the internet as the last medium changed the way of understanding or perception of religious learning. At the same time, some new issues have been opened, starting from the most banal, will the Internet itself ever serve as a source of the sacred or spiritual, till to the nuances where the inevitability of religious internet existence (Internet-based religion) should not be prejudged, but it is already trying to find the answer to the question of how to maximize the use of internet connectivity for the ever-defined function of religion.The Internet has profoundly shaped our world and has changed our lives. The global trend of a parallel life in the internet (or using the internet) did not bypass our country. Thus, the institutions of the Serbian Orthodox Church took up their place. Despite the existence of official websites, social networks such as Facebook, Twitter and others, they are considered as an equally nice place for online religious life in Serbia and they are engaged in religious practices.This paper will be an attempt to define a style that will provide a description of the manner in which the Serbian Orthodox Church through the history has adapted its messages to new channels of communication and what form the church word had at the very beginnings of religious self-awareness, its development over time and what is its form in the era of "online self-awareness". Through such a view, the aim of this paper is to show what is the function or role of the Serbian Orthodox Church as an important agent of the information and communication system.
Ciudadanía digital y educación: nuevas ciudadanías para nuevos environments
Authors: Cobo Cristóbal 
Published: April 2019

<p>La noción de ciudadanía digital adaptada a la educación no sólo implica integrar las tecnologías digitales al servicio de la instrucción sino también incluye revisar las dinámicas de cómo enseñamos y cómo aprendemos con tecnología. La ciudadanía digital implica poder comprender qué significa habitar los circuitos digitales sin descuidar las responsabilidades asociadas. Es decir, pensar en un desempeño adecuado en múltiples entornos digitales en términos de participación, respeto, intercambio, colaboración y convivencia con otros. Partiendo de esta premisa, el artículo invita a la reflexión acerca de los desafíos para comprender las nuevas reglas de interacción y construcción de sociedad en el mundo de Internet.</p><p>Este artículo es una adaptación del capítulo “La triangulación entre contenido, contenedor y contexto”,<em> </em>del<em> </em>libro <em>La innovación pendiente</em> (Cobo, 2016). El autor agradece a Sofia Doccetti por su apoyo en la revisión de este texto. </p><p>Para visualizar el video vaya al siguiente enlace: <a title="https://youtu.be/i2fEmNm5mw4" href="https://youtu.be/i2fEmNm5mw4" target="_blank">https://youtu.be/i2fEmNm5mw4</a></p>
Apropiación social de tecnologías digitales en un contexto de trabajo informal y precario
Authors: Hernández Razo Óscar Enrique , López Sandoval María Guadalupe 
Published: April 2019

<div class="page" title="Page 1"><div class="layoutArea"><div class="column"><p><strong>Objetivo - </strong><span>analizar, desde una perspectiva sociocultural, el proceso de apropiación social de tecnologías digitales en un taller familiar de bordado ubicado en Cuautepec, un área urbana de bajos ingresos en la periferia norte de la Ciudad de México.</span></p><p><strong>Método - </strong><span>se realizó un diseño metodológico de tipo cualitativo, de enfoque etnográfico. Para recabar y construir los datos se utilizaron observaciones, entrevistas semi-estructuradas y demostraciones de uso de tecnología. Se analizó la forma en que los propietarios del taller tomaron decisiones sobre lo que necesitan aprender para transitar del uso de una máquina de bordar eléctrica al uso de una bordadora digital. </span></p><p><strong>Resultados - </strong><span>la adquisición y el uso de los dispositivos digitales motivaron cambios en la distribución de tareas en el taller de bordado. El proceso de apropiación social de tecnologías digitales en un contexto laboral precario se articuló a partir de las condiciones materiales y decisiones familiares para adquirir el equipo digital, la interacción con mediadores con quienes se compartieron ideas y conocimientos sobre el uso de los dispositivos, y la participación de actores designados para usar las nuevas herramientas. Sin embargo, prevalecieron condiciones de desigualdad en el acceso a prácticas sociales con tecnologías digitales. </span></p><p><strong>Limitaciones - </strong><span>entre las limitaciones del trabajo está la falta de profundidad en la exploración del papel de figuras que, desde la perspectiva sociocultural, son importantes en la apropiación social de tecnologías digitales, como el caso de los mediadores. Esto puede ser desarrollado de manera específica en futuras investigaciones.</span></p><p><strong>Principales hallazgos - </strong><span>se muestra que, en el proceso de apropiación social de la tecnología, en un entorno de precariedad laboral y económica, los lazos familiares y de confianza juegan un papel relevante para compartir conocimiento y resolver problemas que se presentan en la actividad. </span></p></div></div></div>
CARTOGRAFÍA DE UNA CONCEPCIÓN PRAGMATISTA DE LOS PROBLEMAS PÚBLICOS
Authors: Márquez Murrieta Alicia 
Published: April 2019

<p>En este artículo hacemos una revisión de algunos conceptos que nos ayudan a pensar los problemas públicos desde una perspectiva pragmatista. Para llegar a ello, realizamos una breve síntesis de los aportes a esta temática realizados durante los años sesenta y setenta por autores de la escuela de Chicago, ello se presenta en la primera parte del artículo. En un segundo apartado, exponemos las cercanías y las distancias que sostienen con esta escuela los autores franco parlantes que nos interesan; también aquí presentamos los que nos parecen sus principales aportes al estudio de los problemas públicos. Por último, sintetizamos los elementos que consideramos de utilidad para pensar hoy en día una sociología pragmatista de los problemas públicos y terminamos el texto haciendo un breve recuento de aquellos puntos que a nuestro parecer no han sido suficientemente desarrollados por estos autores, abriendo con ello una posible agenda de investigación.</p><p> </p>
Automatización del proceso de simulación para el análisis de rendimiento del protocolo TCP en redes inalámbricas
Authors: Trinidad Franco Alejandro , Gonzalez Claudia , Talay Carlos , Rodríguez Herlein Diego 
Published: April 2019

Al trabajar con distintas herramientas de simulación de redes, uno de los inconvenientes más notables es la necesidad de llevar a cabo la generación de un modelo, la ejecución de pruebas y la obtención de resultados para cada caso de estudio. Este proceso insume mucho tiempo debido a los desafíos técnicos involucrados y sólo una vez finalizado, es posible realizar un análisis valorativo de los datos obtenidos. Para detectar casos cuyos resultados pudieran ser de interés, el proceso deberá repetirse varias veces, lo que incrementa el tiempo entre la concepción de un problema y el análisis de los resultados.
El objetivo principal de este trabajo fue reducir el tiempo requerido para implementar y probar un modelo. Esto se logró al establecer una base de simulación con parámetros relevantes en el estudio de rendimiento de TCP, para poder automatizar de forma eficiente la generación de pruebas, el procesamiento y presentación de datos. Gracias a esto se pueden obtener los resultados en menos tiempo, dando paso a la etapa de evaluación.
Como se optó por NS-2, la base de simulación está implementada en el lenguaje OTcl. El procesamiento de datos se hizo mediante scripts de awk, perl y python. Para la presentación visual se utilizó gnuplot. Finalmente, se usó bash para unir todas las partes del proceso, coordinando su ejecución, ordenando los datos y ofreciendo información relevante en cada paso.
Como resultado se logró optimizar el flujo de trabajo para el análisis de rendimiento del protocolo TCP sobre diferentes topologías, reconociendo más rápidamente aquellos escenarios con resultados prometedores. A partir de los datos obtenidos, se exploraron hipótesis que sirvieron de base para la escritura de publicaciones científicas.
Plan de registro, catalogación e inventario de la Colección del Museo de Informática de la UNPA-UARG: puesta en valor de la colección
Authors: Avendaño Rosana , Sofía Albert Anibal Osiris 
Published: April 2019

Todo museo tiene como finalidad registrar, investigar, conservar y exhibir al público sus colecciones, y el Museo de Informática de la UNPA-UARG no escapa a ello. Creado en el año 2009 a través de un proyecto de extensión, este musemuseumo, en sus inicios solo realizaba muestras temporales en diferentes espacios dentro de la universidad, mientras que la colección se encontraba distribuida en los diferentes edificios de la alta casa de estudios.
Desde el año 2015, el museo cuenta con espacio propio para exhibiciones y un repositorio. No obstante, el traslado de la colección al repositorio dejó al descubierto la necesidad de contar información precisa sobre los objetos. Por ello, el desafío más importante era iniciar el trabajo de catalogación, inventariado y preservación de los mismos.
En el marco de los proyectos de Investigación 29/A323 “Pensando en el Museo de Informática de la UNPA-UARG: Plan Museológico y Sistema Documental” año 2015, y Proyecto 2016-2018 29/A368 “El Museo de Informática de la UNPA- UARG: organización, acciones y difusión”, fue una tarea primordial continuar con la etapa final de traslado y limpieza y creación del inventario de la colección. Como así también el registro oral de la historia y evolución de la Tecnología en la provincia de Santa Cruz.
Efecto comparativo de la virulencia de los hongos Aphanocladium album (preuss) Gams y Tolypocladium cylindrosporum Gams (Deuteromycotina- Hyphomycetes), contra larvas de mosquito (Diptera, Culicidae)
Authors: Lopez Claudia , García Juan , Reboredo Guillermo 
Published: April 2019

El presente trabajo ha sido realizado con el objeto de evaluar el efecto potencial patogénico de conidios y blastosporas de Aphanocladium album y Tolypocladium cylindrosporum contra larvas de Culex pipiens L.Un alto porcentaje de mortalidad larval se observó frente a las 2 especies fúngicas, siendo para A.album, 85,6% y para T.cylindrosporum 80%, con dosis de 1 x 106 conidios/ml.En A. album la actividad de blastosporos y conidios fué similar, mientras que para T. cylindrosporum fueron más virulentos los conidios que las blastosporas.De los resultados obtenidos se deduce que ambas especies fúngicas tienen una elevada virulencia contra larvas de C. pipiens y sus potencialidades patogénicas justifican nuevos estudios sobre este tema.
Amanita phalloides en bosques de Pinus radiata de la IX región de Chile: taxonomía, toxinas, métodos de detección,intoxicación faloidiana
Authors: Valenzuela E. , Moreno G. , Jeria M. 
Published: April 2019

Se cita por primera vez para Chile Amanita phalloides (Vaill. ex Fr.) Secr., junto a su descripción macro y microscópica, y algunos aspectos de su ecología. Se aporta infomación sobre sus toxinas, métodos dedetección y cuadro clínico de la intoxicación faloidiana.