bluuebunny/crossref_metadata_2025_split huggingface dataset:
How consumer trust affects the adoption of e-healthcare products on mobile apps: an analysis of perceived usefulness, time, and price
Authors: Gupta Om Jee , Srivastava Manoj K. , Darda Pooja , Yadav Susheel , Mishra Vinaytosh 
Published: November 2024

Purpose
E-healthcare has gained importance, particularly in emerging economies, because of its ability to provide health-care products and services while minimizing contact with the external world, which was particularly relevant during the COVID-19 pandemic. Despite its advantages, consumers seem hesitant to use mobile apps to access such services. Previous research has found that perceived usefulness, time consumption and price significantly impact consumer willingness to purchase e-healthcare products on mobile apps. This study aims to investigate the role of consumer trust in the willingness to purchase e-healthcare products on mobile apps while controlling for the effects of perceived usefulness, time consumption and price.

Design/methodology/approach
Data have been collected using non-probability judgmental and snowball sampling techniques from five major cities in India. After the data cleaning process, 238 questionnaires were used for data analysis in this study. The authors used confirmatory factor analysis to validate all the constructs and subsequently used the hierarchical regression technique to conduct this study.

Findings
The study’s findings show that consumer trust is the most crucial factor for predicting a willingness to purchase e-healthcare products through mobile apps, despite several other variables that also have a positive impact. These findings present important practical implications for mobile app developers, health-care professionals and lawmakers to further enhance the adoption of e-healthcare products on mobile apps.

Research limitations/implications
The research was conducted by considering primarily young adults (those between the ages of 20 and 45 – above) and targeted five cities in India. This highlights a limitation in the research, as small groups of the intended audience were included (mainly young people).

Originality/value
This study considers perceived usefulness, time and price, in addition to trust, to predict consumer willingness to purchase. Its findings can be valuable in the fields of consumer behavior, health care and technology, especially in emerging markets.
Integrating a digital pedagogy approach into online teaching: are academic librarians at Universities of Technology in South Africa prepared?
Authors: Omarsaib Mousin 
Published: November 2024

Purpose
This paper aims to explore whether academic librarians at the Universities of Technology (UoTs) in South Africa have the pedagogy and digital skills to implement a digital pedagogy approach for online teaching.

Design/methodology/approach
A mixed-method approach in the form of a sequential explanatory design was selected to explore the topic in which the quantitative was followed by the qualitative phase. Instruments used included an online questionnaire and semi-structured interviews to explore the pedagogy and digital skills of academic librarians at UoTs in South Africa.

Findings
The quantitative results and findings revealed that academic librarians lacked the pedagogy and digital skills for online teaching. Similarly, results and findings in the qualitative phase also showed academic librarians lacking these skills for online teaching. Consequently, the results and findings derived from both phases were triangulated and the cohesive nature of the data was absolute.

Research limitations/implications
(i) Library schools include an elective module covering pedagogy and teaching with technology for librarians; (ii) library professional bodies create opportunities for academic librarians to develop pedagogy and digital skills; and (iii) higher education libraries need to create knowledge-sharing opportunities to improve the pedagogy and digital skills of academic librarians with teaching portfolios.

Practical implications
Higher education libraries and library schools must promote the teaching identity of academic librarians by helping them improve their pedagogical and digital skills for online teaching.

Social implications
This topic requires further exploration as academic librarians are fast becoming integrated into the teaching and learning agenda of institutions globally.

Originality/value
The current study is novel in that it explores the pedagogical and digital skills of academic librarians at UoTs in South Africa for online teaching.
The impact of innovation and differentiation strategy on financial performance with emphasis on the role of risk management and intellectual capital
Authors: Vaghfi Seyedhesam , Kamranrad Sedighe , Keshvari Fateme 
Published: November 2024

Purpose
The purpose of this study is to investigate the impact of innovation and differentiation strategy on financial performance with a focus on the role of risk management and intellectual capital of companies listed on the Tehran Stock Exchange.

Design/methodology/approach
In this research, differentiation and innovation strategy criteria are the independent variables, performance criteria are the dependent variables and risk management effectiveness and intellectual capital are the moderating variables. The statistical population of this research includes all the companies listed in the Tehran Stock Exchange during the 10-year period, and 127 companies were selected as a statistical sample using the systematic elimination method. The research model fitting and hypothesis testing were carried out using structural equation modeling and SPSS, Smart PLS software.

Findings
The results of the hypothesis testing showed a positive and significant relationship between the innovation and differentiation strategy and the firm performance. In addition, effective management of risk and intellectual capital also had a significant and positive impact on this relationship.

Research limitations/implications
Given that this research was conducted at the Tehran Stock Exchange, it was difficult for the researchers to collect data. Also, since the Tehran Stock Exchange is a new market, a lot of research needs to be done in different areas of this market to identify the existing problems and shortcomings and to provide reasons for its growth and development.

Practical implications
According to the results of the research on the impact of intellectual capital and risk management on corporate performance and the impact of strategy on this relationship, this paper can expect to see an improvement in corporate performance and an increase in shareholder wealth as a result of applying the results of this research.

Social implications
Considering that corporate strategy, intellectual capital criteria and risk management to increase the financial performance of companies have informational content; therefore, according to the results of this research, an increase in the performance of listed companies is expected, and naturally, this increase in performance will lead to the prosperity of the economic sector, increase in job creation and as a result, improve the quality of social life.

Originality/value
In the Tehran Stock Exchange, by properly evaluating the financial performance criteria of companies and identifying the factors that increase intellectual capital and risk management, they provide the means to improve knowledge in this area of research.
Personality, loneliness and the metaverse: exploring their interaction for higher education in marketing
Authors: Maldonado-López Belén , Ledesma-Chaves Pablo , Gil-Cordero Eloy 
Published: November 2024

Purpose
Given the scarce research on the intention to use the metaverse by higher education students in the marketing field and since the introduction of the metaverse brings a new dimension to consumer interaction, the purpose of this study aims to understand what psychological and contextual factors such as the feeling of loneliness or perceived social risk of young people affect the incorporation of immersive reality tools in the teaching-learning process.

Design/methodology/approach
Currently, the use of the metaverse in university education has captured the interest of teachers and researchers. The adoption of immersive virtual platforms where students experience different forms of interaction through customized avatars appears as a promising opportunity in the field of marketing, while concerns arise about the social and psychological risks that may affect its main adopters, youth. The proposed relationships were evaluated using PLS-SEM (symmetric) and QCA (asymmetric) approaches.

Findings
The results revealed that the feeling of loneliness, as well as personality traits of openness to experience and conscientiousness, in relation to hedonic motivations, are significant for the intention to use the metaverse.

Research limitations/implications
This research provides useful implications from an educational perspective, as well as applications in the commercial management of immersive platforms, taking into account their social impact, allowing for effective exploration and development of the metaverse’s potential in educational environments.

Originality/value
This research analyzes the relationship between the experience of feelings of loneliness and perceived social risk in the educational environment, along with the psychological and motivational factors affecting the intention to use the metaverse by higher education students which have not been investigated in the scientific literature so far.
Exploring digital voices to evaluate user perception, satisfaction and service quality in libraries
Authors: Khan Aasif Mohammad , Parray Umer Yousuf , Loan Fayaz Ahmad , Parray Shahid Rashid 
Published: November 2024

PurposeThis study has aimed to thoroughly assess user sentiments and perceptions regarding the National Library of India (NLI). It has attempted to provide significant insights into user satisfaction by examining its strengths and shortcomings across key categories including collection, environment, facilities, location, management and staff. The study has contributed to the understanding of the factors influencing the attributes of libraries, facilitating improvements in services and enhancing the overall user experience.Design/methodology/approachThis study employed a mixed-methods approach combining quantitative and qualitative analysis to assess user sentiments towards the NLI. Using Google Maps reviews, the study utilized web scraping, content analysis and sentiment analysis to categorize reviews as positive, negative or neutral, providing insights into user experiences and an in-depth analysis of the views and opinions of the NLI.FindingsThe study involved sentiment analysis and content analysis of 818 Google Maps reviews to assess user satisfaction with the NLI. The results demonstrate 624 reviews as positive sentiments, 70 instances pinpointed specific negative concerns, primarily related to staff behavior and certain facilities, and 124 neutral reviews suggested mixed viewpoints among users. This analysis highlights the critical role of attributes such as collection quality, environment and facilities in shaping user perceptions, emphasizing the need for focused improvements based on user feedback. The study revealed six attributes, namely collection, environment, facilities, location, management and staff that influence the user perception.Research limitations/implicationsThis study is focused solely on Google Maps reviews. Hence, the results cannot be generalized to all online platforms. Reliance on online reviews may not fully capture the views of all the library users. Additionally, the scope of the study is limited to English-language comments, potentially overlooking valuable insights from non-English-language reviews.Practical implicationsThis study provides valuable insights for the NLI to enhance user satisfaction by addressing the specific concerns raised in online reviews. The findings offer actionable guidance for library management to refine services and maintain favorable public perceptions.Originality/valueThis study contributes to the field by providing a comprehensive analysis of user sentiment through sentiment and content analysis of online reviews, offering unique insights into the NLI’s public perception. The identification of key strengths and weaknesses adds practical value to library management for refining services. The originality of this study lies in its unique approach to evaluating user experiences, which guides future research and improvement efforts in library services.
A comprehensive review of structure–activity relationships and effect mechanisms of polyphenols on heterocyclic aromatic amines formation in thermal‐processed food
Authors: Dong Hao , Ye Huiping , Bai Weidong , Zeng Xiaofang , Wu Qingping 
Published: November 2024

AbstractHeterocyclic aromatic amines (HAAs) are potent carcinogenic substances mainly generated in thermal‐processed food. Natural polyphenols have been widely used for inhibiting the formation of HAAs, whereas the effect of natural polyphenols on HAAs formation is complex and the mechanisms are far from being clearly elucidated. In order to clarify the comprehensive effect of polyphenols on HAAs, this review focused on the structure–activity relationships and effect mechanisms of polyphenols on the formation of HAAs. In addition, the effects of polyphenols on HAAs toxicity were also first reviewed from cell, gene, protein, and animal aspects. An overview of the effect of polyphenol structures such as parent ring and exocyclic group on the mitigation of HAAs was emphasized, aiming to provide some valuable information for understanding their effect mechanism. The HAAs formation is inhibited by natural polyphenols in a dose‐dependent manner largely through eliminating free radicals and binding precursors and intermediates. The inhibitory effect was probably affected by the quantity and position of hydroxyl groups in the aromatic rings, and polyphenols with m‐hydroxyl group in the aromatic ring had the stronger inhibitory effect. However, the presence of other substituents and excessive hydroxyl groups in natural polyphenols might mitigate the inhibitory effect and even promote the formation of HAAs. This review can provide theoretical reference for effectively controlling the formation of HAAs in thermal‐processed food by natural polyphenols and reducing their harm to human health.
Microplastics from face masks: Unraveling combined toxicity with environmental hazards and their impacts on food safety
Authors: Pei Luyu , Sheng Lina , Ye Yongli , Sun Jiadi , Wang Jia‐Sheng , Sun Xiulan 
Published: November 2024

AbstractMicroplastics (MPs) refer to tiny plastic particles, typically smaller than 5 mm in size. Due to increased mask usage during COVID‐19, improper disposal has led to masks entering the environment and releasing MPs into the surroundings. MPs can absorb environmental hazards and transfer them to humans and animals via the food chain, yet their impacts on food safety and human health are largely neglected. This review summarizes the release process of MPs from face masks, influencing factors, and impacts on food safety. Highlights are given to the prevalence of MPs and their combined toxicities with other environmental hazards. Control strategies are also explored. The release of MPs from face masks is affected by environmental factors like pH, UV light, temperature, ionic strength, and weathering. Due to the chemical active surface and large surface area, MPs can act as vectors for heavy metals, toxins, pesticides, antibiotics and antibiotic resistance genes, and foodborne pathogens through different mechanisms, such as electrostatic interaction, precipitation, and bioaccumulation. After being adsorbed by MPs, the toxicity of these environmental hazards, such as oxidative stress, cell apoptosis, and disruption of metabolic energy levels, can be magnified. However, there is a lack of comprehensive research on both the combined toxicities of MPs and environmental hazards, as well as their corresponding control strategies. Future research should prioritize understanding the interaction of MPs with other hazards in the food chain, their combined toxicity, and integrating MPs detection and degradation methods with other hazards.
On excessive entry in Bayes‐Cournot oligopoly
Authors: Bisceglia Michele , Padilla Jorge , Perkins Joe , Piccolo Salvatore 
Published: November 2024

AbstractIn a Cournot industry where firms are privately informed about their marginal costs, raising entry barriers (i.e., imposing strictly positive, but not too large, entry costs) increases expected output, entrants' profits, total welfare, and might benefit consumers. Under Bayes‐Cournot competition, firms react to the expectation (conditional on entry) of rivals' costs rather than to their actual costs. This creates scope for entry by relatively inefficient types. Entry costs that prevent these high‐cost types from entering increase inframarginal (lower‐cost) types' and rivals' expected output. As a result, they increase profits and, unless they reduce output variability too much, also consumer surplus.
OFDI and stock price synchronicity: Evidence from China
Authors: Wang Yanyi , Zhang Xueyong 
Published: November 2024

AbstractUsing the data on outward foreign direct investment (OFDI) by listed companies in China, we find that OFDI significantly increases stock price synchronicity. This result indicates that OFDI releases more market/industry (systematic) information relative to private information. Reverse technology spillover and the host country/region institutional environment are two potential mechanisms through which OFDI increases synchronicity. We find that OFDI plays a role in screening firms with better transparency and corporate governance. The propensity score matching method and instrumental variable regressions are employed to rule out endogeneity issues. We also check the impact of stock return characteristics and macro shocks on this positive relationship.
Integration of pharmacochemistry, pharmacodynamics and metabolomics to reveal active ingredients and mechanism of Nan Bao detox capsule alleviating methamphetamine addiction
Authors: Zhang Bin , Yang Chen , Zheng Yuxiao , Li Xinliang , Wang Xingguo , Yuehui Li 
Published: November 2024

AbstractNan Bao detox capsule (NBDC), derived from ancient Chinese opioid detox protocols, shows promising therapeutic potential in substance abuse disorders, particularly for attenuating methamphetamine (MA) addiction. This study aimed to identify active ingredients, evaluate therapeutic efficacy in an MA addiction rat model and delineate pharmacodynamic mechanisms using metabolomics. In vitro phytochemical profiling characterized 258 drug‐related compounds, with 87 prototype entities mainly identified in rat plasma. NBDC significantly attenuated METH‐induced behavioural anomalies and modulated neurotransmitter levels, notably increasing brain DA and serotonin (5‐HT) content with concomitant upregulation of D1 dopamine receptor (DRD1) and 5‐HT1A receptor (5‐HT1AR) expression, ameliorating hippocampal pathology. Metabolomic analysis identified histamine receptor as a potential target and revealed the involvement of NBDC in metabolic pathways associated with cocaine addiction, amphetamine abuse and Parkinson's disease. Conclusively, NBDC presents a promising therapeutic agent for mitigating MA addiction through a synergistic interplay of multiple constituents, pharmacological targets and metabolic pathways.
Floral morphology is associated with pollen deposition patterns on moth bodies
Authors: Buxton Max N. , Gaskett Anne C. , Lord Janice M. , Pattemore David E. 
Published: November 2024

AbstractFloral syndromes can be a useful tool for predicting the identity of pollinators from floral morphology. However, the reliability of floral syndromes are still debated in the literature, and can often result in effective pollinators being overlooked. Pollination by moths has historically been associated with a floral syndrome comprising white tubular flowers that are heavily scented at night, but there have been few experimental tests of this association. To test whether moths preferentially land on flowers that are white and tubular, we allowed two moth species (Agrotis ipsilon (Hufnaggel, 1766) and Ichneutica mutans (Walker, 1857)) to choose freely between three plant species (Vaccinium corymbosum, Ericaceae, Pittosporum tenuifolium, Pittosporaceae, and two forms of Leptospermum scoparium, Myrtaceae) which represent four different floral morphologies. Anthers on the flowers were marked with fluorescent powder dye (pollen‐tracker), with the presence of pollen‐tracker on moth bodies after the experiment indicating floral visitation. We detected no floral preferences for any of the plant species by either moth species, suggesting moths will visit flowers that lack features associated with the syndrome even when in the presence of white, tubular flowers which might be predicted to be more attractive to moths. We also examined moth bodies to determine where pollen‐tracker was carried most often and if this varied among the floral types. Our results indicate that some moth body parts may be more important than others for pollen transfer, depending on the morphology of the flowers visited. After visiting tubular flowers (Vaccinium and Pittosporum), pollen‐tracker was most often located on the proboscis, but after visiting open‐access flowers (Leptospermum) pollen‐tracker was most often located on the legs. Future studies looking at the presence of pollen on moth bodies should consider this and ensure the entire moth body is examined for the presence of pollen.
Feedback regulation of VISTA and Treg by TNF‐α controls T cell responses in drug allergy
Authors: Sun Lele , Zhao Qing , Ao Suiting , Liu Tingting , Wang Zhenzhen , You Jiabao , Mi Zihao , Sun Yonghu , Xue Xiaotong , Ogese Monday O. , Gardner Joshua , Meng Xiaoli , Naisbitt Dean J. , Liu Hong , Zhang Furen 
Published: November 2024

AbstractBackgroundSevere cutaneous adverse reactions (SCARs) mediated by cytotoxic T lymphocytes are a series of life‐threatening conditions with a mortality of 4%–20%. The clinical application of tumor necrosis factor‐alpha (TNF‐α) antagonist improves the outcome of some SCARs patients; however, this is complicated by the elusive and varied immunopathogenesis.MethodsTo clarify the precise process and optimize the therapy regimen of SCARs, we performed single‐cell sequencing, in vitro functional and clinical analysis of patients with SCARs.ResultsWe observed that TNF‐α breaks drug‐specific T‐cell tolerance by inhibiting the expression of V‐type immunoglobulin domain‐containing suppressor of T‐cell activation (VISTA). Furthermore, TNF‐α generated a positive feedback loop in the early phase of drug‐specific T‐cell activation, whereby B cells acted reciprocally on the corresponding T cells to reinforce TNF‐α cytokine expression. In contrast, this pathway of TNF‐α‐VISTA signaling did not operate in memory effector T cells. Drug‐specific memory effector T‐cell responses were inhibited by increasing Treg cell expression in a negative feedback loop, with TNF‐α antagonists preventing the inhibitory effect. These observations align with the clinical analysis that early but not late intervention with TNF‐α antagonists significantly improved outcomes in SCARs patients.ConclusionOur findings defining feedback regulation of VISTA and Treg cells by TNF‐α in different stages of the drug‐specific T‐cell response and, indicate that a Treg agonists, instead of TNF‐α antagonists, could be used for treatment of patients with progressive SCARs.