bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation and Selection of Sustainable Strategy for Green Supply Chain Management Implementation
Authors: Malviya Rakesh Kumar , Kant Ravi , Gupta Ashim Dutta 
Published: March 2018

AbstractThe aim of this study is to explore the implementation of green supply chain management (GSCM) strategies and to select the best GSCM strategy using fuzzy analytical network process (ANP) methodology. The ANP helps in analyzing the interdependence and interrelations among the various determinants and dimensions of GSCM strategy selection. Fuzzy set theory is applied to avoid the vagueness and uncertainty in human preference judgement. This study uses an empirical case study of an Indian automobile organization to validate the applicability of the proposed model. The results show that the resource based strategy is in first position, having the maximum impact on each determinant. The case organization should improve the green management system with the assistance of a suitable GSCM strategy, i.e. the resource based strategy. This study may help managers to make decisions, and to analyze and standardize their environmental advantages dynamically. The robustness of the projected model is checked by conducting a sensitivity analysis. Copyright © 2018 John Wiley & Sons, Ltd and ERP Environment
Prostate cancer surveillance by occupation and industry: the Canadian Census Health and Environment Cohort (CanCHEC)
Authors: Sritharan Jeavana , MacLeod Jill , Harris Shelley , Cole Donald C. , Harris Anne , Tjepkema Michael , Peters Paul A. , Demers Paul A. 
Published: March 2018

AbstractAs there are no well‐established modifiable risk factors for prostate cancer, further evidence is needed on possible factors such as occupation. Our study uses one of the largest Canadian worker cohorts to examine occupation, industry, and prostate cancer and to assess patterns of prostate cancer rates. The Canadian Census Health and Environment Cohort (CanCHEC) was established by linking the 1991 Canadian Census Cohort to the Canadian Cancer Database (1969–2010), Canadian Mortality Database (1991–2011), and Tax Summary Files (1981–2011). A total of 37,695 prostate cancer cases were identified in men aged 25–74 based on age at diagnosis. Cox proportional hazards models were used to estimate hazards ratios and 95% confidence intervals. In men aged 25–74 years, elevated risks were observed in the following occupations: senior management (HR = 1.12, 95% CI: 1.04–1.20); office and administration (HR = 1.19, 95% CI: 1.11–1.27); finance services (HR = 1.09, 95% CI: 1.04–1.14); education (HR = 1.05, 95% CI: 1.00–1.11); agriculture and farm management (HR = 1.12, 95% CI: 1.06–1.17); farm work (HR = 1.11, 95% CI: 1.01–1.21); construction managers (HR = 1.07, 95% CI: 1.01–1.14); firefighting (HR = 1.17, 95% CI: 1.01–1.36); and police work (HR = 1.22, 95% CI: 1.09–1.36). Decreased risks were observed across other construction and transportation occupations. Results by industry were consistent with occupation results. Associations were identified for white‐collar, agriculture, protective services, construction, and transportation occupations. These findings emphasize the need for further study of job‐related exposures and the potential influence of nonoccupational factors such as screening practices.
The impact of comorbidity on overall survival in elderly nasopharyngeal carcinoma patients: a National Cancer Data Base analysis
Authors: Huang Ying , Chen Wei , Haque Waqar , Verma Vivek , Xing Yan , Teh Bin S. , Brian Butler Edward 
Published: March 2018

AbstractThe number of elderly patients with cancer is increasing. Medical comorbidities are more common in this population. Little is known regarding the prognostic relevance of comorbidities in elderly patients with nasopharyngeal carcinoma (NPC). Using the National Cancer Data Base (NCDB), we queried patients age >65 years diagnosed with NPC and treated with definitive radiation between 2004 and 2012 to examine the association between comorbidity and survival outcomes. Comorbidity was assessed with the Charlson Comorbidity Index (CCI). The influence of comorbidity on overall survival (OS) was evaluated. Cox proportional hazards model was used to study the impact of comorbidity on OS. A total of 1137 patients met the specified criteria. Median follow‐up was 61.2 months. Five‐year OS was 50.4%. Comorbidities were present in 22.4% of patients, with 17.6% of patients having a CCI score of 1% and 4.8% having a CCI score of ≥2. Patients with a CCI score of 0 had significantly higher 5‐year OS than patients with a CCI score of 1 or ≥2 (53.1% vs. 42.2% vs. 32.9%, P < 0.001). In multivariate analysis, CCI was a statistically significant independent prognostic factor for the risk of death of all causes for patients with a CCI score of 1 (hazard ratio [HR]: 1.242; 95% confidence interval [CI]: 1.002–1.539) or CCI score of ≥2 (HR: 1.625; 95% CI: 1.157–2.283) when compared to patients with a CCI score of 0. Comorbidity as measured by CCI is a strong independent prognostic factor for OS in elderly patients with NPC and lends support to the inclusion of comorbidity assessment due to its prognostic value when treating elderly patients with NPC.
Social class and the therapeutic relationship: The perspective of therapists as clients. A qualitative study using a questionnaire survey
Authors: Trott Alison , Reeves Andrew 
Published: March 2018

AbstractBackgroundThis research aimed to explore clients’ perceptions of the impact of social class and whether, if so how, perceived social class disparities impact upon the therapeutic relationship.MethodA total of 45 completed questionnaires, via an online survey, were returned, comprising 30 middle‐class and 15 working‐class qualified and practising therapists from their role as client. A quasi‐phenomenological approach was taken and thematic analysis used to interrogate the data.FindingsFour primary themes were identified as follows: (1) Perceptions of own social class; (2) Social class as a facilitative aspect of therapy; (3) Negative impact of social class on therapy; and (4) Clients perceptions of their therapeutic relationship. The findings show that where there was social class disparity, it was the explicit recognition and acknowledgement of disparity that were shown to have a positive impact on the client; improving equality, increasing rapport and enabling greater psychological growth.Implications for practiceTherapists’ lack of awareness of social class was shown to lead to inadvertent oppressive and/or classist behaviour. For a client to take full benefit from therapy, therapists must recognise the importance of social class and classism and their impact upon the therapeutic relationship, and be prepared to attend to these dynamics when appropriate.ConclusionsThough many respondents thought social class was an irrelevant factor within their therapeutic relationship, this study illustrates that social class was a silent but powerful force affecting clients’ feelings of equality and the effectiveness of therapy.
The N‐Terminal Domain of the Pullulanase from Anoxybacillus sp. WB42 Modulates Enzyme Specificity and Thermostability
Authors: Wang Jianfeng , Liu Zhongmei , Zhou Zhemin 
Published: March 2018

AbstractAnoxybacillus sp. WB42 pullulanase (PulWB42) is a novel thermophilic amylopullulanase that was assigned to the glycoside hydrolase family 13 subfamily 14 (GH13_14) type I pullulanases in the carbohydrate‐active enzymes database. Its N‐terminal domain (Met1–Phe101) was identified as the carbohydrate‐binding module 68 (CBM68) by homology modeling. The N‐domain‐deleted PulWB42 exhibited an equivalent Michaelis constant (Km) for pullulan and significant decreases in pullulytic activity, amylose selectivity, and thermostability relative to PulWB42 having a high α‐amylase‐to‐pullulanase activity ratio. Furthermore, the replacement of Ala90 or Arg93 significantly changed the substrate specificity and catalytic efficiency of PulWB42, whereas Q87A, L173D, and H5A/R6A/T7A showed improvements in thermostability and changes in catalytic kinetics. Therefore, the N domain of PulWB42 is not essential for catalysis, but it does modulate enzyme catalysis, especially with respect to substrate specificity. The modulation was achieved mainly by the Leu86–Arg93 segment adjacent to the CBM48 domain and the catalytic A domain in the modeled structure of PulWB42.
kNN based on probability density for fault detection in multimodal processes
Authors: Guo Jinyu , Wang Xin , Li Yuan 
Published: March 2018

AbstractRecently, k‐nearest neighbor rules (kNN) have drawn increasing attention for fault detection of multimodal industrial processes. However, the traditional kNN method performs poorly for weak faults in a dense mode when the dispersion degree of each mode is quite different. The reason is that the kNN statistics of weak faults are usually submerged by those of normal data in a mode with a high dispersion degree. To improve the fault detection performance of kNN in this case, this paper proposes a new multimodal fault detection method of kNN based on probability density. The proposed method does not need to consider the different degrees of dispersion between modes and avoids the problem of weak faults in a mode that has a low dispersion degree that is submerged by normal data in a mode with a high dispersion degree. A multimodal numerical example with different dispersion degrees of each mode and an industrial application in a semiconductor manufacturing process are used to verify the effectiveness of the proposed method. The simulation results demonstrate that the proposed method shows better fault detection performance than the kNN, local outlier factor, and weighted difference principal component analysis methods.
Cp2TiX Complexes for Sustainable Catalysis in Single‐Electron Steps
Authors: Richrath Ruben B. , Olyschläger Theresa , Hildebrandt Sven , Enny Daniel G. , Fianu Godfred D. , Flowers Robert A. , Gansäuer Andreas 
Published: March 2018

AbstractInvited for the cover of this issue are the groups of Robert Flowers at Lehigh University and Andreas Gansäuer at Universität Bonn. The image depicts a titanocene complex picking the best “fruit” from a selection of anions for catalysis. Read the full text of the article at 10.1002/chem.201705707.
Automatic translation from Java to Spark
Authors: Li Bing , Xiao Xueli , Pan Yi 
Published: March 2018

SummaryCloud computing is a powerful infrastructure tool for scientific computing and research and attracts many developers to deploy their products on it. Code migration from local to cloud servers is a significant challenge for all companies and organizations that have many legacy programs. Compared to the de novo development method, the automatic translation is more productive and economical. In this paper, a new Java to Spark (J2S) translator is introduced to achieve the automatic translation from sequential Java code to Spark cloud application, which can translate three types of computing intensive programs. The evaluation experiments demonstrate that these translations significantly improve the source program performance in their domains. It is believed that it is a new step in the automatic code migration era of cloud computing.
Dynamic behavior of different quantities of osteoblasts during formation of micromass cultures
Authors: Schäfer Susanne , Urban Kent , Gerber Maria , Dekiff Markus , Dirksen Dieter , Plate Ulrich 
Published: March 2018

AbstractImplantation of micromass cultures of osteoblastic cells offers the possibility of scaffold free tissue engineering for example, regeneration of bone defects. However, the details of cell dynamics during the formation of these micromasses are still not well understood. This study aims to investigate and clarify the extent to which cell quantity influences the dynamics of micromass formation of osteoblastic cell cultures. For this purpose, the migration and aggregation during this process are investigated by optical inspection employing image processing software that allows for automated tracking of cell groups using digital image correlation. An exponential time behavior is observed with respect to the velocity of the cells and the distance of the cells to their common center of gravity. Characteristic time constants are derived as quantitative measures of the cell dynamics. The results indicate that the time constants strongly depend on the quantity of cells, that is, will decrease with increasing cell quantity. © 2018 International Society for Advancement of Cytometry
Outcomes of low‐weight patients with avoidant/restrictive food intake disorder and anorexia nervosa at long‐term follow‐up after treatment in a partial hospitalization program for eating disorders
Authors: Bryson Amanda E. , Scipioni Anna M. , Essayli Jamal H. , Mahoney Johnna R. , Ornstein Rollyn M. 
Published: March 2018

AbstractObjectiveTo assess long‐term outcomes of patients with avoidant/restrictive food intake disorder (ARFID) treated in a partial hospitalization program (PHP) for eating disorders (ED).MethodA cross‐sectional study comparing patients with ARFID to those with anorexia nervosa (AN) who had been discharged from a PHP for at least 12 months was performed. Percent median body mass index (%MBMI), scores on the Children's Eating Attitudes Test (ChEAT), and treatment utilization were assessed, with intake and discharge data collected via retrospective chart review.ResultsOf the 137 eligible patients, 62 (45.3%) consented to follow‐up data collection. Patients with ARFID and AN exhibited similar increases in %MBMI from intake to discharge and reported low scores on the ChEAT by discharge. Patients with ARFID and AN maintained good weight outcomes and low ChEAT scores at follow‐up. Most participants were still receiving outpatient treatment from a variety of providers, although fewer with ARFID than AN continued to receive services from our multidisciplinary ED clinic.DiscussionPatients with ARFID and AN exhibit similar improvements in %MBMI when treated in the same PHP and appear to maintain treatment gains at long‐term follow‐up. Additionally, most patients continue to utilize outpatient services after being discharged from a PHP.
Range Extension Autonomous Driving for Electric Vehicle Based on Optimal Vehicle Velocity Profile in Consideration of Cornering
Authors: Ikezawa Yuta , Fujimoto Hiroshi , Kawano Daisuke , Goto Yuichi , Takeda Yusuke , Sato Koji 
Published: March 2018

SUMMARYElectric vehicles (EVs) have been intensively studied in the last decade due to their environment‐friendly characteristics. However, the miles‐per‐charge of EVs is less than that of internal combustion engine vehicles. To improve the miles‐per‐charge, the authors’ group proposed a Range Extension Autonomous Driving (READ) system that minimizes consumption energy by optimizing the velocity profile. However, conventional systems can be applied to driving on only straight roads. Therefore, this study extends READ system to be applied to driving not only on straight roads but also on curved roads by modeling the vehicle rotation motion and the cornering resistance. The effectiveness of the proposed method is verified by simulations and experiments.
Direct comparison of ultrafiltration to pharmacological decongestion in heart failure: a per‐protocol analysis of CARRESS‐HF
Authors: Grodin Justin L. , Carter Spencer , Bart Bradley A. , Goldsmith Steven R. , Drazner Mark H. , Tang W.H. Wilson 
Published: March 2018

AimsMechanical ultrafiltration (UF) involves the removal of an iso‐osmotic filtrate from the blood. Its benefit in acute decompensated heart failure, however, remains inconclusive. We sought to better understand the direct effects of UF in comparison to an aggressive, urine output‐guided pharmacological protocol for decongestion on fluid loss, renal function, and neurohormonal activation.Methods and resultsA per‐protocol analysis of the Cardiorenal Rescue Study in Acute Decompensated Heart Failure (CARRESS‐HF) trial (n = 188) was performed. Participants were included if randomized to UF and had UF output collected, or if randomized to the pharmacological arm and had urine but not UF output collected. Using these definitions, there were 163 participants at 24 h, 156 at 48 h, 129 at 72 h, and 106 at 96 h. UF was associated with higher cumulative fluid loss (P = 0.003), net fluid loss (P = 0.001), and relative reduction in weight (P = 0.02). UF was also associated with higher serum creatinine and blood urea nitrogen by 72 h (P‐interaction <0.05 for both), lower serum sodium by 48 h (P‐interaction <0.01) and increased plasma renin activity by 96 h (P = 0.04). The pharmacological arm was associated with higher serum bicarbonate after 24 h (P‐interaction <0.002). There were no differences in 60‐day outcomes between the UF and pharmacological arms.ConclusionsUltrafiltration vs. pharmacological therapy was associated with more fluid removal but also rise in serum creatinine and neurohormonal activation. Additionally, loop diuretic use vs. UF was associated with an increase in serum bicarbonate despite less decongestion, data which question the commonly held conception of a ‘contraction alkalosis’.
Pt‐Sn Nanoparticles Supported on Carbon Nanodots as Anode Catalysts for Alcohol Electro‐oxidation in Acidic Conditions
Authors: Gwebu Sandile Surprise , Nomngongo Philiswa Nosizo , Maxakato Nobanathi Wendy 
Published: March 2018

AbstractThe Pt‐Sn/CNDs electrocatalyst was synthesized by the alcohol reduction method with the aim to reduce platinum loading and improve electroactivity. XPS results showed that the nanoparticles were present in the form of Pt‐Sn metallic alloy with a significant amount of SnO‐ species which facilitate the rapid oxidation of CO intermediates. The lattice parameter of Pt in Pt‐Sn/CNDs electrocatalyst was calculated to be 0.3926 nm; this value is higher than 0.3921 nm, the lattice parameter of Pt in Pt/CNDs electrocatalyst. XRD results proved that incorporating tin (Sn) into the Pt/CNDs electrocatalyst modifies the face centred cubic shape of platinum to a crystalline structure which improves the alcohol electro‐oxidation reactions. The electrochemical tests proved that the Pt‐Sn/CNDs electrocatalyst exhibited high current densities and lower poisoning rates compared to the Pt/CNDs and Pt/C electrocatalysts. The Pt‐Sn/CNDs electrocatalyst showed the greatest electroactivity for both methanol and ethanol electro‐oxidation reactions.
Adverse outcome pathway networks II: Network analytics
Authors: Villeneuve Daniel L. , Angrish Michelle M. , Fortin Marie C. , Katsiadaki Ioanna , Leonard Marc , Margiotta-Casaluci Luigi , Munn Sharon , O'Brien Jason M. , Pollesch Nathan L. , Smith L. Cody , Zhang Xiaowei , Knapen Dries 
Published: March 2018

Abstract

Toxicological responses to stressors are more complex than the simple one-biological-perturbation to one-adverse-outcome model portrayed by individual adverse outcome pathways (AOPs). Consequently, the AOP framework was designed to facilitate de facto development of AOP networks that can aid in the understanding and prediction of pleiotropic and interactive effects more common to environmentally realistic, complex exposure scenarios. The present study introduces nascent concepts related to the qualitative analysis of AOP networks. First, graph theory–based approaches for identifying important topological features are illustrated using 2 example AOP networks derived from existing AOP descriptions. Second, considerations for identifying the most significant path(s) through an AOP network from either a biological or risk assessment perspective are described. Finally, approaches for identifying interactions among AOPs that may result in additive, synergistic, or antagonistic responses (or previously undefined emergent patterns of response) are introduced. Along with a companion article (part I), these concepts set the stage for the development of tools and case studies that will facilitate more rigorous analysis of AOP networks, and the utility of AOP network-based predictions, for use in research and regulatory decision-making. The present study addresses one of the major themes identified through a Society of Environmental Toxicology and Chemistry Horizon Scanning effort focused on advancing the AOP framework. Environ Toxicol Chem 2018;37:1734–1748. © 2018 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals, Inc. on behalf of SETAC. This article is a US government work and, as such, is in the public domain in the United States of America.
Abstract
On the performance of asymmetric SIM‐based RF/FSO system with MIMO DF relaying
Authors: Singhal Neha , Bansal Ankur , Kumar Ashwni 
Published: March 2018

AbstractIn this paper, we consider the asymmetric dual‐hop radio frequency (RF) and free‐space optical (FSO) wireless communication system with a decode‐and‐forward–based multiple‐input–multiple‐output relay over the Nakagami‐m/Generalized‐K(
) distribution. The
distribution is a generic statistical model, which has been used for a wide range of atmospheric turbulence–induced fading in FSO communication. The coefficients of the RF hop are considered to be independent and nonidentically distributed with the Nakagami‐m distribution, and the coefficients of FSO hop are considered to be independent and identically distributed. We also consider the path loss and misalignment error effect in FSO hop. We derive the approximate closed‐form expression of the symbol error probability and outage probability in terms of the Meijer G function for the considered mixed decode‐and‐forward RF/FSO system. The closed‐form expressions of the conditional symbol error probability and outage probability are also derived for the considered system while taking into account the effect of a misalignment error. We have also analyzed the considered system for high signal‐to‐noise ratio conditions. In addition, the diversity order of the considered system is also obtained analytically.
Aging‐associated changes in hippocampal glycogen metabolism in mice. Evidence for and against astrocyte‐to‐neuron lactate shuttle
Authors: Drulis‐Fajdasz Dominika , Gizak Agnieszka , Wójtowicz Tomasz , Wiśniewski Jacek R. , Rakus Dariusz 
Published: March 2018

AbstractLactate derived from astrocytic glycogen has been shown to support memory formation in hippocampi of young animals, inhibiting it in old animals. Here we show, using quantitative mass spectrometry‐based proteomics, immunofluorescence, and qPCR that aging is associated with an increase of glycogen metabolism enzymes concentration and shift in their localization from astrocytes to neurons. These changes are accompanied with reorganization of hippocampal energy metabolism which is manifested by elevated capacity of aging neurons to oxidize glucose in glycolysis and mitochondria, and decreased ability for fatty acids utilization. Our observations suggest that astrocyte‐to‐neuron lactate shuttle may operate in young hippocampi, however, during aging neurons become independent on astrocytic lactate and the metabolic crosstalk between the brain's cells is disrupted.