bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diskussion
Authors: Staub Sabina 
Published: October 2024

ZusammenfassungIn diesem Kapitel erfolgt eine Verschiebung des Fokus von den spezifischen Fallstudien auf eine allgemeine Ebene, um die empirischen Ergebnisse für weitere Forschung und die Praxis nutzbar zu machen. Zu diesem Zweck werden pädagogische Konsequenzen formuliert und Forschungsdesiderate identifiziert. Im Anschluss an die Einordnung der empirischen Ergebnisse erfolgt eine Reflexion des methodischen Vorgehens. Abschließend wird eine Zusammenfassung der gesamten Untersuchung einschließlich eines Ausblicks präsentiert.
Leitlinienempfohlene standardisierte Instrumente bei multipler Sklerose
Authors: Bolte Jasmin , Dilger Elise-Marie , Brütt Anna Levke 
Published: October 2024

Zusammenfassung
Hintergrund
Leitlinien sind praxisorientierte Entscheidungshilfen und empfehlen die Verwendung standardisierter Instrumente zur Messung der Funktionsfähigkeit von Menschen mit multipler Sklerose (MS). Inwieweit diese durch die empfohlenen Instrumente erfasst wird, ist allerdings unklar.

Ziel der Arbeit
In dieser Studie werden die Inhalte standardisierter Instrumente, die bei Menschen mit MS eingesetzt werden, mit der Internationalen Klassifikation der Funktionsfähigkeit, Behinderung und Gesundheit (ICF) abgeglichen, um die Verteilung der Inhalte auf die Funktionsdomänen und Kontextfaktoren zu beschreiben.

Material und Methoden
Eingeschlossen wurden alle Instrumente, die in der S2k-Leitlinie „Diagnose und Therapie der Multiplen Sklerose, Neuromyelitis-optica-Spektrum-Erkrankungen und MOG-IgG-assoziierten Erkrankungen“ beschrieben wurden. Die Items der Instrumente wurden inhaltlich analysiert, indem sie in ihre sinnvollen Konzepte („meaningful concepts“ [MC]) eingeteilt und mittels standardisierter Regeln der ICF durch zwei Rater zugeordnet wurden.

Ergebnisse
Die 23 eingeschlossenen Instrumente beinhalten 351 Items und 718 MC. Von diesen konnten 663 MC in der ICF abgebildet werden. 51 % (n = 340 MC) bezogen sich auf Körperfunktionen, 44 % (n = 291 MC) auf Aktivität und Teilhabe und 5 % (n = 32 MC) auf Umweltfaktoren. Das Kapitel Mobilität (d4) war mit n = 201 MC am stärksten in den Instrumenten vertreten. Die Interrater-Reliabilität lag bei k = 0,79.

Diskussion
Die leitlinienempfohlenen Instrumente decken viele Bereiche der ICF ab, jedoch sind die Umweltfaktoren unterrepräsentiert. Die ICF-Verknüpfung erleichtert die Auswahl geeigneter Instrumente für Forschung und Praxis.
Critical machining parameters for large aircraft casing production considering the influence of clamping systems
Authors: González Barrio Haizea , Escudero Gaizka Gómez , Del Olmo Ander , de Pisson Gonzalo Martínez , Marin Felipe , de Lucio Pablo Fernández 
Published: October 2024

AbstractIn recent years, there has been a notable initiation or acceleration in the production of new aeronautical engines. This surge is coupled with a global commitment to reducing emissions and mitigating noise generated by gas turbines used in aeronautical applications. A critical component in this context is the aeronautical casing. The manufacturing process is intricate and time-consuming, compounded by the complexity of the clamping system, which poses a significant challenge to productivity. This study undertakes a comprehensive analysis of the critical variables essential for the optimal manufacturing of a zero-defects large-scale casing. The examination encompasses design criteria, raw materials, constraints related to clamping systems and tooling, and process monitoring. Ultimately, the exploration extends to the examination of more sustainable manufacturing techniques. To facilitate this, a case study involving the fabrication of a life-size aeronautical casing is undertaken.
Digitale Freihandelszonen: Staatlich unterstützte Plattformisierung und ihre Auswirkungen auf den E-Commerce und Logistiksektor in Malaysia
Authors: Hardaker Sina , Biersack Patrick 
Published: October 2024

ZusammenfassungDie kürzlich in Malaysia und Thailand eröffneten Digitalen Freihandelszonen (Digital Free Trade Zones; DFTZ) sind vor dem Hintergrund globaler wirtschaftlicher Veränderungen und zunehmender Digitalisierung ein markantes Beispiel für die staatlich unterstützte Plattformisierung im E‑Commerce- und Logistiksektor. Diese Entwicklung birgt sowohl Chancen als auch Herausforderungen für Unternehmen, Politik und Planung. Der vorliegende Beitrag betrachtet zunächst die zugrunde liegende Logistikinfrastruktur der Zonen und erörtert auf Basis von Interviews mit beteiligten Akteuren der malaysischen Freihandelszone die Gründe zur Etablierung der DFTZs sowie die Auswirkungen auf den Einzelhandel und Logistiksektor. In diesem Kontext liefert der Beitrag vertiefte Einblicke in den Einfluss von Alibaba auf den globalen E‑Commerce- und Logistiksektor sowie dessen Rolle als politisches Instrument für die regionale Wirtschaftsentwicklung.
Adult mental health outcomes of adolescent depression and co-occurring alcohol use disorder: a longitudinal cohort study
Authors: Bohman Hannes , Låftman Sara Brolin , Alaie Iman , Ssegonja Richard , Jonsson Ulf 
Published: October 2024

AbstractDepression and alcohol use disorder (AUD) are frequently co-occurring in adolescence, which often goes undetected in routine care. While this may potentially compromise treatment effectiveness and lead to a less favourable long-term prognosis, few longitudinal studies have followed this group into adulthood. The aim of this study was to explore the risk for adult depression, anxiety disorders, suicidality, and AUD in adolescents with concurrent depression and AUD. The study was based on the Uppsala Longitudinal Adolescent Depression Study (ULADS), a Swedish prospective cohort study. Diagnostic interviews were conducted in adolescence (age 16-17) and adulthood (around age 30). Adolescents with concurrent depression and AUD (n = 38) were compared with peers having only depression (n = 189) or neither of the conditions (n = 144). Logistic regression was used to calculate adjusted odds ratios (aORs) with 95% confidence intervals (CIs). Adolescents with concurrent depression and AUD were more likely than their non-affected peers to experience adult depressive episodes (aOR, 5.33; 95% CI, 2.22–12.83), anxiety disorders (4.05; 1.77–9.27), suicidality (5.37; 2.28–12.66), and AUD (7.68; 2.59–22.81). Notably, 34% of adolescents with both depression and AUD subsequently experienced both these conditions as adults, compared to 7% of adolescents with only depression. Adolescents suffering only from depression were less likely than those with both conditions to experience suicidality (0.44; 0.21–0.95) and AUD in adulthood (0.18; 0.07–0.44). These findings underscore the clinical imperative to identify adolescents with this comorbidity. Recognition of the poor long-term prognosis can inform targeted interventions for this vulnerable group, ultimately improving health and well-being throughout the life course.
Risk and protective factors for mental health problems in children and adolescents during the COVID-19 pandemic: results of the longitudinal COPSY study
Authors: Zoellner F. , Erhart M. , Napp A.-K. , Reiss F. , Devine J. , Kaman A. , Ravens-Sieberer U. 
Published: October 2024

AbstractThe COVID-19 pandemic has had profound effects on the mental health of children and adolescents worldwide, exacerbating existing challenges and introducing new stressors. This paper explores the impact of risk and protective factors on the mental well-being of young individuals during the pandemic. Using data from the German nationwide, population-based, longitudinal COPSY study (n = 2,471, girls: 50.0%, age 7–17 years) spanning nearly three years, this study investigates how factors such as gender, age, parental education, parental depressive symptoms, family cohesion, and social support influence mental health. Mental health problems were assessed using the Strengths and Difficulties Questionnaire (SDQ). Latent growth analysis and structural equation modeling were employed to analyze cross-sectional and longitudinal data collected at five measurement points (initial response rate: 46.8%). Findings revealed that boys and younger children are at a higher risk for mental health problems. Additionally, low parental education, single parenthood, parental burden due to the pandemic and parental depressive symptoms were significantly linked with mental health problems in children. Conversely, personal resources, family cohesion, and social support were associated with less symptoms. Family cohesion additionally buffered against the negative impact of parental depressive symptoms. The study underscores the importance of multi-level interventions that consider individual, familial, and societal factors in promoting positive mental health outcomes among children and adolescents during challenging times. Continued research and collaborative efforts are needed to develop evidence-based strategies for supporting the resilience of young individuals in the face of future adversities.
Early antiplatelet therapy after intravenous thrombolysis for acute ischemic stroke: a systematic review and meta-analysis
Authors: Kelani Hesham , Naeem Ahmed , Elhalag Rowan H. , Abuelazm Mohamed , Albaramony Nadia , Abdelazeem Ahmed , El-Ghanem Mohammad , Quinoa Travis R. , Greene-Chandos Diana , Berekashvili Ketevan , Tiwari Ambooj , Kay Arthur D. , Lerner David P. , Merlin Lisa R. , Al-Mufti Fawaz 
Published: October 2024

Abstract

Background
Early neurological deterioration (END) and recurrence of vessel blockage frequently complicate intravenous thrombolysis (IVT) for acute ischemic stroke (AIS). Several studies have indicated the potential effectiveness of the early initiation (within < 24 h) of antiplatelet therapy (APT) after IVT. However, conflicting results have been reported by other studies. We aimed to offer a thorough overview of the current literature through a systematic review and meta-analysis.

Methods
Our systematic review and meta-analysis were prospectively registered on PROSPERO (ID: CRD42023488173) following the PRISMA guidelines. We systematically searched Web of Science, SCOPUS, PubMed, and Cochrane Library until May 5, 2024. Rayyan. ai facilitated the screening process. The R statistical programming language was used to calculate the odds ratios and conduct a meta-analysis. Our primary outcomes were excellent functional recovery (modified Rankin Scale score 0–1), symptomatic intracranial hemorrhage (sICH), and mortality.

Results
Eight studies involving 2,134 participants were included in the meta-analysis. Early APT showed statistically significant increased odds of excellent functional recovery (mRS 0–1) compared to the standard APT group (OR, 1.81; [95% CI: 1.10, 2.98], p = 0.02). However, we found no differences between the early and standard APT groups regarding sICH (OR, 1.74; [95% CI: 0.91, 3.33], p = 0.10) and mortality (OR, 0.88; [95% CI: 0.62, 1.24]; p = 0.47).

Conclusion
Early APT within 24 h of IVT in stroke patients is safe, with no increase in bleeding risk, and has a positive effect on excellent functional recovery. However, there was a statistically insignificant trend of increased sICH with early APT, and the current evidence is based on highly heterogeneous studies. Further large-scale RCTs are warranted.
New LAMBDA toolbox for mixed-integer models: estimation and evaluation
Authors: Massarweh Lotfi , Verhagen Sandra , Teunissen Peter J. G. 
Published: October 2024

Abstract
In this work we introduce the LAMBDA 4.0 toolbox, which provides an enhanced implementation for integer estimation, validation, and success rate evaluation. This free and open-source toolbox is a major update to LAMBDA 3.0 (2012), while it also integrates the functionalities from Ps-LAMBDA 1.0 (2013), thus respectively merging both estimation and evaluation capabilities. The new implementation provides redefined algorithms, such as an improved integer search strategy with a one-order reduction in the computational time, along with additional estimators: Vectorial Integer Bootstrapping (VIB), Integer Aperture Bootstrapping (IAB) and Best Integer Equivariant (BIE). This toolbox aims to become a valuable resource for researchers and/or practitioners dealing with mixed-integer models in high dimensions, e.g., terrestrial-based carrier-phase systems, multi-constellation Global Navigation Satellite Systems (GNSS), or other interferometric applications.
The evolution of ageing: classic theories and emerging ideas
Authors: Mc Auley Mark T. 
Published: October 2024

Abstract
Ageing is generally regarded as a non-adaptive by-product of evolution. Based on this premise three classic evolutionary theories of ageing have been proposed. These theories have dominated the literature for several decades. Despite their individual nuances, the common thread which unites them is that they posit that ageing results from a decline in the intensity of natural selection with chronological age. Empirical evidence has been identified which supports each theory. However, a consensus remains to be fully established as to which theory best accounts for the evolution of ageing. A consequence of this uncertainty are counter arguments which advocate for alternative theoretical frameworks, such as those which propose an adaptive origin for ageing, senescence, or death. Given this backdrop, this review has several aims. Firstly, to briefly discuss the classic evolutionary theories. Secondly, to evaluate how evolutionary forces beyond a monotonic decrease in natural selection can affect the evolution of ageing. Thirdly, to examine alternatives to the classic theories. Finally, to introduce a pluralistic interpretation of the evolution of ageing. The basis of this pluralistic theoretical framework is the recognition that certain evolutionary ideas will be more appropriate depending on the organism, its ecological context, and its life history.
Studies on morpho-structure and ionic conductivity of apatite-type lanthanum silicate doped with transitional metal cations
Authors: Perhaita Ioana , Muresan Laura Elena , Borodi Gheorghe , Popa Adriana , Nicoara Adrian , Tudoran Lucian Barbu 
Published: October 2024

AbstractOxy-apatite lanthanum silicates with general formula La10Si5.9M0.1O27±δ (M = Cr3+, Mn4+, Fe3+, Mo6+, W6+; 0.05 ≤ δ ≤ 0.1, coded LaSiMO) were obtained by gel-combustion and they were characterized through electrochemical impedance spectroscopy. The XRD patterns show that all samples adopt apatite structure and crystallize in the hexagonal space group P-3(147) with crystallite sizes ranging from 86 nm to 103 nm. The dopant cations were accommodated at Si position with the highest occupancy factor at O6 sites (responsible in conduction) for LaSiCrO and LaSiFeO apatites. Fe and Cr doped samples contain pure apatite phase while those doped with Mn, Mo, W contain La2SiO5 as secondary phase which act as insulator in conduction process. Based on EPR and ICP-OES investigations we found that Mn, Mo, W cations present multiple oxidation states in the apatite lattice and a lower incorporation degree in comparison with Fe and Cr cations. Local distortions are present in Fe and Cr doped apatite lattices which explains the higher ionic conductivity of these samples. At 500oC, the ionic conductivities, range between 1.15·10− 4 and 3.56·10− 4 S·cm− 1 for samples sintered at 1400oC, values that are higher than un-doped apatite (6.46·10− 5 S·cm− 1). Due to the highest ionic conductivity among the samples, LaSiCrO was additionally sintered at 1500oC and 1600oC in order to investigate the role of temperature on ionic conduction process. The relative density of LaSiCrO was improved from 89.03 to 93.06% and the ionic conductivity reach 0.28·10− 2 S·cm− 1, at 600oC. The results of this study show that apatites doped with Cr and Fe may be used as electrolytes in SOFCs.
Structural investigation and dc conductivity of Bi2O3–B2O3 glasses
Authors: El-Egili K. , Ghazal R. 
Published: October 2024

AbstractThe structure of xBi2O3∙(100–x)B2O3 with (30 ≤ x ≤ 65 mol%) glasses was investigated by FTIR, XRD, TEM, SEM and dc conductivity. The factor of four coordinated boron atoms N4 increases up to 50 mol% Bi2O3 then decreases for further increase in Bi2O3 content. FTIR analyses indicate that Bi2O3 heads for creating a matrix of its own rather than modifying the borate matrix and this behavior gradually increases with increasing its concentration in the matrix. There is a linear increase in both experimental density and molar volume values with replacing B2O3 by Bi2O3, moreover a strong correlation between the computed and experimental density and molar volume values could be noticed. XRD patterns confirm that no sharp peaks for untreated samples whereas Bi2O3 crystalline phase appears for heat treated samples. TEM and SEM show the presence of some small phases with different sizes formed of clusters, these phases increase in size and became predominant with heat treatment. The conductivity increases while the activation energy seems to be constant. This rare behavior is interpreted in the light of forming Bi2O3 former matrix.
Hematopoietic Stem Cell Transplantation for C1q Deficiency: A Study on Behalf of the EBMT Inborn Errors Working Party
Authors: Buso Helena , Adam Etai , Arkwright Peter D. , Bhattad Sagar , Hamidieh Amir Ali , Behfar Maryam , Belot Alexandre , Benezech Sarah , Chan Alice Y. , Crow Yanick J. , Dvorak Christopher C. , Flinn Aisling M. , Kapoor Urvi , Lankester Arjan , Kobayashi Masao , Matsumura Risa , Mottaghipisheh Hadi , Okada Satoshi , Ouachee Marie , Parvaneh Nima , Ramprakash Stalin , Satwani Prakash , Sharafian Samin , Triaille Clément , Wynn Robert F. , Movahedi Nasim , Ziaee Vahid , Williams Eleri , Slatter Mary , Gennery Andrew R. 
Published: October 2024

AbstractC1q deficiency is a rare inborn error of immunity characterized by increased susceptibility to infections and autoimmune manifestations mimicking SLE, with an associated morbidity and mortality. Because C1q is synthesized by monocytes, to date, four patients treated with allogeneic HSCT have been reported, with a positive outcome in three. We conducted an international retrospective study to assess the outcome of HSCT in C1q deficiency. Eighteen patients, fourteen previously unreported, from eleven referral centres, were included. Two patients had two HSCTs, thus 20 HSCTs were performed in total, at a median age of 10 years (range 0.9—19). Indications for HSCT were autoimmune manifestations not controlled by ongoing treatment in seventeen, and early development of MALT lymphoma in one patient. Overall survival (OS) was 71% and event-free survival was 59% at two years (considering an event as acute GvHD ≥ grade III, disease recurrence and death). In eleven patients HSCT led to resolution of autoimmune features and discontinuation of immunosuppressive treatments (follow-up time range 3–84 months). Five patients died due to transplant-related complications. Patients with a severe autoimmune phenotype, defined as neurological and/or renal involvement, had the worst OS (40% vs 84%; p = 0.034). Reviewing data of 69 genetically confirmed C1q deficient patients, we found that anti-Ro antibodies are associated with neurologic involvement, and anti-RNP and anti-DNA antibodies with renal involvement. In conclusion, HSCT may be a valid curative option for C1q deficiency, but careful selection of patients, with an accurate assessment of risk and benefit, is mandatory.
A Consistent Kinetic Fokker–Planck Model for Gas Mixtures
Authors: Pirner Marlies 
Published: October 2024

AbstractWe propose a general multi-species Fokker–Planck model. We prove consistency of our model: conservation properties, positivity of all temperatures, H-Theorem and the shape of equilibrium as Maxwell distributions with the same mean velocity and temperature. Moreover, we derive the usual macroscopic equations from the kinetic two-species BGK model and compute explicitly the exchange terms of momentum and energy.
Revisiting Shimizu et al. (2004): What do we know and what should we know about cross-border mergers and acquisitions?
Authors: Wiedemann Manuel , zu Knyphausen-Aufseß Dodo , Ippendorf Niko 
Published: October 2024

AbstractCross-border mergers and acquisitions (M&A) constitute an important phenomenon due to their volumes, frequencies, and strategic relevance for business practice. Academia has recognized the phenomenon’s importance and compiled a wide spectrum of research. However, to the best of our knowledge, research has not provided a consolidation of recent literature findings particularly focused on cross-border M&A (as opposed to domestic M&A) since the publication of Shimizu et al.’s review in 2004. With this article we intend to close this gap by identifying, categorizing, synthesizing, and integrating recent literature to better understand what we do as well as what we should know about cross-border M&A. Thereby, literature findings are examined and discussed according to three perspectives: cross-border M&A as a (1) market entry mode, (2) dynamic learning process, and (3) value creating strategy. Based on the review, future research needs and opportunities are elaborated, first by directly following the findings from the review of the three research streams, and subsequently by adopting an overarching view that takes into account recent developments in multinational enterprise theory into account and addresses the “grand challenges” currently facing modern societies.
Implementation Science and Pediatric Diabetes: A Scoping Review of the State of the Literature and Recommendations for Future Research
Authors: Price Julia , Hawkins Jaclynn , Amante Daniel J. , James Richard , Haire-Joshu Debra 
Published: October 2024

Abstract
Purpose of Review
This scoping review aimed to identify implementation science (IS) research in pediatric diabetes, report integration of IS theory and terminology, and offer guidance for future research.

Recent Findings
Of 23 papers identified, 19 were published since 2017 and 21 focused on type 1 diabetes. Most involved medical evidence-based practices (EBPs; n = 15), whereas fewer focused on psychosocial (n = 7) and diabetes education (n = 2). The majority either identified barriers and facilitators of implementing an EBP (n = 11) or were implementation trials (n = 11). Fewer studies documented gaps in EBP implementation in standard care (n = 7) or development of implementation strategies (n = 1). Five papers employed IS theories and two aimed to improve equity.

Summary
There is a paucity of IS research in pediatric diabetes care literature. Few papers employed IS theory, used consistent IS terminology, or described IS strategies or outcomes. Guidance for future research to improve IS research in pediatric diabetes is offered.
On Autonomous Superposition Operators in Spaces of $$\mu $$–Almost Periodic Functions and Applications to Linear Differential Equations
Authors: Bugajewski Dariusz , Nawrocki Adam 
Published: October 2024

Abstract
In this article we focus mainly on the class of almost periodic functions in view of the Lebesgue measure (briefly:

$$\mu $$

μ

-a.p. functions) and on some if its subclasses. We are going to deal with autonomous superposition operators acting in the space of

$$\mu $$

μ

-a.p. functions. We will indicate necessary and sufficient conditions under which the autonomous superposition operator maps the space under consideration into itself as well as conditions under which it is continuous. As a corollary from these results we indicate when the autonomous superposition operator defined on that space is a bijection. Next, we will analyse in detail the situation when the composition of

$$\mu $$

μ

-a.p. function with a continuous function or with a homeomorphism gives a Stepanov almost periodic function. As an application of our results we indicate a subclass of

$$\mu $$

μ

-a.p. functions for which linear differential equations with a non-homogeneous term belonging to this subclass may not have

$$\mu $$

μ

-a.p. solutions.