bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interfunctional Coordination and its Influence on Customer Success
Authors: Tomaskova Eva 
Published: October 2018

AbstractThe purpose of the paper is to expand the knowledge about interfunctional coordination (IFC). The term IFC has been used for 50 years and it extends to many branches. The most popular ones are in marketing, logistics and IT management. The purpose of IFC is to develop collaboration between the diverse departments within an organization. The goal of the paper is to describe the relationship between IFC on the B2B market, especially if IFC in one company can influence customer success in business. The research was undertaken with companies producing electronic components and electrical equipment in the region of South Moravia in the Czech Republic. 60 SME have answered the questionnaire. The Spearman’s rank correlation test was used to analyse the influence of IFC of companies on the success of their customers. The results show that the implementation of IFC in a company has a positive relationship on the success of its customers.
Serum of coronary atherosclerotic heart disease patients induces oxidative stress injury on endothelial cells
Authors: Pan Huichao , Zhang Min 
Published: October 2018

Abstract
Endothelial cell (EC) dysfunction has a fundamental role in the development of atherosclerosis, which leads to myocardial infarction and stroke. The aim of this study is to investigate the effect of serum from patients with coronary atherosclerotic heart disease (CAD) on endothelial cells and investigate the possible mechanism underlying these effects. Serum from 35 patients with CAD and 35 healthy volunteers was collected. Human umbilical vein endothelial cell (HUVEC) proliferation and apoptosis were assessed by a CCK‑8 assay and a flow cytometry assay, respectively. The synthesis of nitric oxide (NO) and reactive oxygen species (ROS) was measured using the nitrate reduction method and DCFH2-DA staining, respectively. The proliferation of HUVECs was inhibited by treatment with serum from CAD patients (P<0.05). Suppression of HUVEC proliferation by CAD serum occurred in a concentration-dependent manner. The synthesis of NO was also reduced in the CAD serum-treated group. Furthermore, the serum from CAD patients increased both apoptosis and intracellular ROS production in HUVECs. Moreover, treatment with tempol antagonized CAD serum-meditated HUVEC injuries. Taken together, these results suggest that HUVEC injury via CAD serum treatment is mediated by ROS production. Tempol may partly reverse this effect by abolishing HUVEC apoptosis.
HOPX homeobox methylation in differentiated thyroid cancer and its clinical relevance
Authors: Lima Erika Urbano , Rubio Ileana G S , Da Silva Joaquim Custodio , Galrão Ana Luiza , Pêssoa Danielle , Oliveira Taise Cerqueira , Carrijo Fabiane , Silva Campos Igor , Fonseca Espinheira Luciano , Sampaio Luiz Jose , Lima Claudio Rogerio , Cerutti Janete Maria , Ramos Helton Estrela 
Published: October 2018

Background
The inactivation of the tumor-suppressor homeodomain-only protein X (HOPX) usually involves promoter methylation in several cancer types. This study aimed to investigate the HOPX-β mRNA expression and promoter methylation and their clinical relevance in differentiated thyroid cancer (DTC).

Patients and methods
Clinicopathological data and paraffin-embedded thyroid tumor tissues from 21 patients with DTC and 6 with benign tumors (T) and their non-tumor parenchyma (NT) were investigated. Tumor cell lines (FTC238, FTC236 and WRO) were treated with demethylating agent. HOPX-β mRNA expression was assessed by qRT-PCR and methylation status by Q-MSP. Thyroid cancer data from Cancer Genome Atlas (TCGA) was also collected.

Results
HOPX-β mRNA re-expression in two cell lines treated with demethylating agent was observed concomitantly with reduced promoter methylation. Reduced mRNA expression in T group compared to their NT was observed, and reduced protein expression in T compared to NT was observed in three cases. Low mRNA expression with high methylation status was detected in 6/14 DTC samples. High methylation status was associated with older age at diagnosis, recurrent or progressive disease and with the presence of new neoplasm event post initial therapy while hyper-methylation correlated with worse overall survival, worse disease-free status and older age.

Conclusion
A moderate coupling of downregulation of HOPX-β mRNA expression in DTC followed by high HOPX-β promoter methylation was observed however; high HOPX promoter methylation status was associated with the worse prognosis of DTC patients.
Haruki Murakami: El mundo de la soledad en los años de peregrinación del chico sin color
Authors: Rengifo Castillo Yessika María 
Published: October 2018

El presente artículo se instaura desde una reflexión sobre la obra: Los años de peregrinación del chico sin color, de Haruki Murakami. De estas circunstancias nace el hecho de que el tema principal de este trabajo reflexivo, sea la soledad que se desarrolla en la obra. En la que Tsukuru Tazaki el protagonista, comprenderá los acontecimientos que lo han llevado a una vida tranquila, y en soledad. Además, hablar del escritor japonés es hablar de mundos posibles, caracterizados por la tristeza, la melancolía, el amor, la esperanza, el desencuentro, y la soledad. Sentimientos verosímiles que permean a los sujetos de la postmodernidad. Es decir, que los personajes de Murakami luchan por salir de esa búsqueda de identidad, haciéndole resistencia al desencanto que trajo la postmodernidad. Ese himno de soledad que no se reduce a una pérdida del todo, sino al encuentro consigo mismo, con los otros. La soledad como el universo del poder ser, en el camino de lo incierto.
The Effectiveness of Applying Innovative Curriculum in Physical Education Classes / Učinkovitost primjene inovativnih programskih sadržaja u nastavi tjelesne i zdravstvene kulture
Authors: Mandarić Sanja , Jovančević Vojin , Halasi Sabolcs , Lepeš Josip 
Published: October 2018

AbstractThe aim of this research was to identify the effect of programmed classes of step aerobics in 7th grade female pupils. The research was conducted on the sample of 63 seventh-grade female pupils, divided into the experimental (n=32) and control (n=31) target groups. The effects of step aerobics were observed in the area of motor abilities (16 variables) and cardio-respiratory functions (3 variables). The step aerobics classes lasting for eight weeks and conducted within regular PE classes represented the experimental factor. ANOVA 2x2 results indicate that step aerobics classes statistically significantly contributed to the improvement of 15 variables of the experimental group compared to the control group in the area of motor abilities and all variables in the area of cardio-respiratory functions. The greatest improvement was detected in non-rhythmic drumming (F=263.43; p˂0.001), hand and feet drumming (F=103.83; p˂0.001) and maximum oxygen consumption (F=104.29; p˂0.001). Based on the obtained results, we can conclude that step aerobics classes, as an innovative programme component, have practical use in teaching aiming to distribute exercise in a precise manner and to achieve objectives and tasks of physical education. Key words: cardio-respiratory functions; female pupils; modern teaching; motor abilities; step aerobics.---SažetakCilj istraživanja bio je utvrditi učinke programirane nastave step aerobika kod učenica sedmih razreda osnovne škole. Istraživanje je provedeno na uzorku od 63 učenice sedmih razreda osnovne škole, podijeljenih metodom ciljanog uzorka na eksperimentalnu (n=32) i kontrolnu (n=31) skupinu. Učinci step aerobika praćeni su u prostoru motoričkih sposobnosti (16 varijabli) i kardiorespiratornih funkcija (3 varijable). Eksperimentalni čimbenik predstavljala je nastava step aerobika koja je trajala osam tjedana i koja je ostvarena u okviru redovite nastave tjelesne i zdravstvene kulture. Rezultati ANOVA 2x2 ukazuju na to da je nastava step aerobika statistički značajno utjecala na poboljšanje 15 varijabli iz prostora motoričkih sposobnosti i svih varijabli iz prostora kardiorespiratornih funkcija eksperimentalne skupine u odnosu na kontrolnu. Najveći napredak zamijećen je u neritmičkom bubnjanju (F=263.43; p˂0.001), bubnjanju rukama i nogama (F=103.83; p˂0.001) i maksimalnoj potrošnji kisika (F=104.29; p˂0.001). Na temelju dobivenih rezultata može se zaključiti da nastava step aerobika kao inovativan programski sadržaj ima praktičnu primjenljivost u nastavi s ciljem preciznog doziranja vježbanja i ostvarenja cilja i zadataka tjelesne i zdravstvene kulture.Ključne riječi: kardiorespiratorne funkcije; motoričke sposobnosti; step aerobik; suvremena nastava; učenice
Be in: Teach Outdoors!/Budimo in! Podučavajmo vani!
Authors: Borsos Eva , Boric Edita , Patocskai Maria 
Published: October 2018

AbstractThe effectiveness of outdoor education and the effects such education has on pupils, are undeniable, but often, teachers cannot conduct enough classes outdoors due to reasons beyond their influence (lack of time, lack of locations, etc.). The comparative analysis of the National Curricula of Serbia, Hungary and Croatia shows significant similarities. In order to support the teachers, the authors composed a list of viable locations for outdoor learning and categorized these by teaching units. Such locations can be found near every school and thus easily used for outdoor classes. A model program was created containing two outdoor classes for every month. The devised program was implemented and tested in elementary school. Pupils’ opinions on outdoor education were also examined.The results proved the proposed program to be effective, helping pupils come closer to nature, motivating them to become familiar with their environment.Key words: environmental awareness; new model program; outdoor education; primary school. --- SažetakUčinkovitost obrazovanja na otvorenom i učinci takvog obrazovanja na učenike neporecivi su, ali nastavnici često ne mogu održavati dovoljno sati na otvorenom zbog razloga koji su izvan njihova utjecaja (nedostatak vremena, nedostatak mjesta itd.). Usporedna analiza Nacionalnog kurikula Srbije, Mađarske i Hrvatske pokazuje znatne sličnosti.S ciljem podrške nastavnicima autori su sastavili popis održivih lokacija za učenje na otvorenom i kategorizirali ih prema nastavnim jedinicama. Takve se lokacije mogu naći u blizini svake škole i na taj se način lako mogu koristiti za izvanučioničku nastavu. Izrađen je program koji sadrži dva izvanučionička nastavna sata za svaki mjesec. Program je proveden i testiran u osnovnoj školi. Pitali smo i mišljenje đaka o izvanučioničkoj nastavi.Rezultati su pokazali da je predloženi program učinkovit, pomaže učenicima da se približe prirodi, potiče ih da se upoznaju sa svojom okolinom.Ključne riječi: ekološka svijest; novi model programa; izvanučionička nastava; osnovna škola
Monitoring the Artistic Development of Fourth-Year Students – An Analysis of the Situation in Croatian Primary Schools / Praćenje likovnog razvoja učenika četvrtih razreda – analiza stanja u hrvatskim osnovnim školama
Authors: Herzog Jerneja 
Published: October 2018

AbstractThe development of child’s creativity in primary school is not just the task of arts education, but of all school subjects. The overall curriculum should be focused on the development of each person in education, both on the development of her or his knowledge and abilities, and on encouraging creativity in various fields. Respect, release, and development of all child’s potentials is an important condition for creativity, as children have at their disposal a fair amount of abilities needed to create.In the paper, we present the outcomes of a study in which the level of artistic development of fourth-year students was analysed in Croatian primary schools.The results indicate that there are differences in the creative levels, manifested as better results in favour of boys. There are also differences in optical-thematic development, in this case manifested as better results in favour of girls. Key words: artistic creativity; artistic development; primary school; visual culture.---SažetakRazvijanje djetetove kreativnosti u osnovnim školama nije samo zadatak predmeta likovne kulture nego svih predmeta. Sveukupni kurikul morao bi biti usmjeren na razvoj svakog subjekta u odgoju i obrazovanju, kako u razvijanju njegova znanja i sposobnosti tako i u poticanju njegove kreativnosti na raznim područjima. Poštivanje, oslobađanje, poticanje i razvijanje svih djetetovih sposobnosti preduvjet je kreativnosti s obzirom na njegovu inherentnu kreativnu sposobnost. U radu predstavljamo rezultate istraživanja u kojem smo analizirali razinu likovnog razvoja kod učenika četvrtih razreda osnovne škole u hrvatskim osnovnim školama. Rezultati ukazuju na postojanje razlika u razini njihova stvaralaštva, što osobito pokazuju kod kreativnog razvoja. Razlike se uočavaju u korist dječaka, a kod optičko-tematskog razvoja u korist djevojčica. Ključne riječi: likovna kreativnost; likovna kultura; likovni razvoj; osnovna škola
Teachers’ Knowledge on Education for Sustainable Development – Polish Context/Znanje nastavnika o obrazovanju za održivi razvoj – slučaj Poljske
Authors: Mróz Anna , Tomczyk Łukasz , Walotek-Ściańska Katarzyna , Ocetkiewicz Iwona 
Published: October 2018

Abstract The sustainable development model is considered to be the only one implementing the postulate of intra- and intergenerational justice, and allowing modern societies to develop safely. Because education makes it possible to achieve complex social goals, the sustainable development model must be implemented in a modern school. For this purpose, UNESCO experts promote education for sustainable development (ESD) as a response to the challenges of the modern world. The article presents the results of empirical research on teacher knowledge on education for sustainable development. Participants in the research, which was carried out in 2016, were 337 Polish teachers of the lower and upper secondary school. The research analysis showed that Polish teachers are not properly prepared for the implementation of assumptions of education for sustainable development into education programmes - their knowledge in this area is insufficient. Key words: education for sustainable development; school; shaping competencies; sustainability; teacher. --- Sažetak Smatra se da je model održivoga razvoja jedini model koji primjenjuje postulat unutar i međugeneracijske pravednosti te omogućuje siguran razvoj suvremenoga društva. S obzirom na to da obrazovanje omogućuje stjecanje složenih društvenih ciljeva, model održivoga razvoja mora biti primijenjen i u suvremenim školama. S tom svrhom stručnjaci UNESCO-a promoviraju obrazovanje za održivi razvoj (OOR) kao odgovor na izazove suvremenoga svijeta. Rad donosi rezultate empirijskoga istraživanja o znanju nastavnika o obrazovanju za održivi razvoj. U istraživanju koje je provedeno 2016. sudjelovalo je 337 nastavnika nižih i viših razreda srednje škole. Analiza rezultata pokazala je da su poljski nastavnici nedovoljno pripremljeni za provedbu teza iz područja obrazovanja za održivi razvoj u obrazovne programe – njihovo znanje iz spomenutoga područja je nedostatno. Ključne riječi: nastavnik; oblikovanje kompetencija; obrazovanje za održivi razvoj; održivost; škola.
Progress on Coastal Ecosystems: Corals and Mangroves Recovery 12 Years Later after March 2005 Earthquake in North Nias, North Sumatera.
Authors: . Suyarso , Prayuda Bayu , Avianto Praditya 
Published: October 2018

Twelve years ago 9.3 Mw earthquake in the Andaman Islands, on December 26, 2004 accompanied by the tsunami in Aceh led to extraordinary losses, unprecedented for human life in coastal areas of Indonesia and neighboring countries. A few months later, on March 28, 2005 an earthquake 8.7 Mw has occured around Nias, hundreds of hectares of coral reef ecosystems lifted into the terrestrial, many corals die of drought and collapse due to earthquake vibration. Similarly, most of the mangrove moved away from the coastline due to land lifting. The purpose of this study is to determine the development of coastal ecosystems, especially coral reefs have been damaged by the earthquake and mangrove due to changes in the environment. The method used in this study is remote sensing technique through the data acquired from landsat imageries, measurements of coastal profile, coral reef health monitoring data collected in each year at six permanent stations. The field research conducted in August 2005, December 2014 and December 2015, the last two activities are under research collaboration between the Marine Agency of North Nias Regency and Research Center for Oceanography LIPI. The results showed in the period 2007-2010 live coral coverage is likely to increase in the range between 2.23% to 48%. Instead since 2014 showed a significant decrease in almost all stations. Twice earthquakes with 33the magnitude 8.2 Mw and 8.6 Mw occurred almost simultaneously on April 11, 2012 at 400 km southwest of Aceh is thought to play a role in tear down the developing corals. Similarly, the existence of mangrove that has moved away from the coastline due to the land lifting in 2005, species of Rhyzophora desiccated and died slowly but other species such as Aegiceras, Dolichandrone, Xylocarpus and Cheriops appear stayed on the dry land condition and seemed to be growing normally
STUDI AWAL RAJA AMPAT SEBAGAI MARINE ECO ARCHEO PARK: ANALISIS KUALITAS PERAIRAN DI KAWASAN SELAT DAMPIR
Authors: Rustam Agustin , Dillenia Ira , A Troa Rainer , G Bengen Dietriech 
Published: October 2018

Selat Dampir yang berada di daerah Raja Ampat merupakan salah satu gugusan pulau-pulau kecil yang berada di ujung kepala burung pulau Papua bagian dari kawasan Coral Triangle Initiative (CTI) yang memiliki biodiversitas tinggi. Selain itu di lokasi ini terdapat situs arkeologi maritim, sehingga kawasan ini merupakan kawasan yang cocok sebagai kawasan marine eco archeo park. Perlu dilakukan penelitian awal keberadaan lokasi ini seperti kualitas perairan yang dilakukan pada tanggal 7 – 13 Mei 2014. Pengambilan data kualitas perairan dilakukan secara purposive sampling dengan menggunakan alat multiparameter secara in situ dan analisis sampel air di laboratorium. Parameter yang diukur yaitu salinitas, pH, turbiditas, padatan tersuspensi (TSS), Biological Oxygen Demand (BOD5), nitrat, tembaga dan nikel. Analisis data dilakukan secara deskriptif dan menggunakan analisis PCA (Principal Component Analysis). Hasil yang didapat untuk semua parameter masih sesuai dengan KMNLH no 51 tahun 2004, hanya nilai tembaga pada saat pengukuran tidak sesuai, walaupun secara keseluruhan perairan Selat Dampir pada saat pengukuran masih dalam kondisi baik sebagai daerah taman nasional dan wisata bahari. Berdasarkan analisis PCA didapatkan parameter yang berperan kuat di lokasi adalah BOD5, pH, TSS dan kecerahan. Diperlukan penelitian lebih lanjut terkait lokasi penelitian sebagi situs maritim dan daerah wisata bahari di daerah konservasi dalam mewujudkan marine eco archeo park berbasis ekosistem lestari.
KARAKTERISTIK OSEANOGRAFI FISIKA PERAIRAN ESTUARIA BENGKALIS BERDASARKAN DATA PENGUKURAN IN-SITU TAHUN 2015
Authors: Amri Khairul , Muchlizar Muchlizar 
Published: October 2018

Perairan estuaria Bengkalis memiliki peranan yang sangat strategis di tepi alur pelayaran internasional yang paling sibuk di dunia, yaitu Selat Malaka. Perairan ini merupakan daerah pertemuan antara massa air laut dari Selat Malaka dan massa air tawar dari muara Sungai Siak yang sangat khas dan menarik untuk dikaji. Penelitian mengenai karakteristik oseanografi fisika perairan ini dilakukan dalam periode 7 bulan selama tahun 2015. Metode yang digunakan adalah survei secara in-situ menggunakan wahana kapal survei pada 16 stasiun pengukuran. Hasil yang diperoleh menunjukkan bahwa perairan estuaria Bengkalis merupakan perairan dangkal dengan kedalaman berkisar antara 6,1-37,3 m. Jenis-jenis substrat dasar perairan beragam, yaitu kombinasi komponen pasir (2,7-86,69%), debu (10,64-89,82%) dan liat (2,66-13,30%). Pergerakan massa air didominasi oleh arus pasut (arus pasang-surut) dengan kecepatan arus permukaan rata-rata berkisar 0,07-1,19 m/detik. Perairan ini tergolong keruh, dengan kisaran tingkat kecerahan rata-rata antara 0,42-0,95 m. Tingkat kecerahan cenderung menurun pada akhir tahun seiring masuknya musim penghujan. Rata-rata suhu perairan pada lapisan permukaan berkisar antara 29,74-30,94 0C dan di lapisan dasar berkisar antara 29,36-30,63 0C, dengan pola lebih dingin ke arah laut terbuka (Selat Malaka) dan lebih hangat ke arah muara Sungai Siak.
THE SUSTAINABILITY OF TOURISM COMPETITIVENESS IN TERNATE
Authors: LAODE Muharto 
Published: October 2018

This study aims to analyze the competitiveness of tourism sector in Ternate using three units of analysis, namely the sustainability of competitiveness, the determinant of competition strength and the formulation of sustainable competitive advantage strategy. Secondary data were collected through documentation, such as APBD data, infrastructure conditions, tourism objects, labor, industry of accommodation provider, and tourist numbers. Primary data were collected through interview to 159 respondents. The analysis and strategy formulation used combination of VRIOL, SFM and SWOT. This study found that the tourism sector in Ternate was in a competitive advantage position, but not sustained because its tourism resources did not have uniqueness and could be imitated by competitors. Factors determining tourism competition were the role of government, new areas that were beginning to develop the tourism sector, new tourist spot and tour operators. The strategies that could maintain the sustainability of tourism competitiveness in Ternate are differentiation, inovation, partnership, promotion and marketing system, service quality, and empowering.
THE STUDY OF EVALUATION BRICS-T COUNTRIES BASED ON THE GLOBAL COMPETITIVENESS INDEX
Authors: BİL Erkan , GÜDÜK Tanju , KESKİN Gülay 
Published: October 2018

Through globalization, countries aim to have a competitive advantage about trading and increasing financial opportunities in the global market with international collaboration and economic integration. In recent years, the emerging and expanding national economies like Brazil, Russia, India, China and South Africa have became key players and taken investors’ attention globally. In addition to these countries known as BRICS, Turkey is also another expanding national economy that attracts investors with strong economic growth in the last 20 years. Therefore, recently the idea of becoming one of the members of BRICS for Turkey has been considered.
Nowadays, the index research studies which show the global competitiveness, rankings and detailed data profiles of the international markets are published by different authorities. One of the highly trusted authorities, World Economic Forum publishes Global Competitiveness Index every year.
The purpose of this study is to indicate similarities and differences among these 6 countries (BRICS-T) and also define comparison to each other based on the data from Global Competitiveness Index (2017-2018). In the process of analyzing the data, multidimensional scale has been used. According to the data of Global Competitiveness Index (2017-2018), the similarities are more likely to be found between Russia and Turkey while India and China also project similar features together. The most different features have been observed between Brazil and China. The similarities are based on detailed data company profiles of global competitiveness. In conclusion, the result shows that Russia and Turkey are seen as one group while China and India generate also another group together. On the other hand, Brazil and South Africa stand alone in their own groups. Key Words: Global Competitiveness Index, WEF, BRICS-T, Multidimensional Scale