bluuebunny/crossref_metadata_2025_split huggingface dataset:
Protocol development and feasibility of the PEACH in Asia study: A pilot study on PEri‐anesthetic morbidity in CHildren in Asia
Authors: Obara Soichiro , Bong Choon Looi , Ustalar Ozgen Zehra Serpil , Abbasi Shemila , Rai Ekta , Villa Evangeline K. , Ramlan Andi Ade W. , Zahra Raihanita , Kapuangan Christopher , Ferdiana Komang Ayu , Shariffuddin Ina Ismiarti , Yuen Vivian , Varghese Elsa , Tan Josephine S. K. , Kuratani Norifumi ,   Asian Society of Pediatric Anesthesiologists (ASPA) research special interest group
Published: November 2024

AbstractBackgroundComprehensive data on pediatric anesthesia outcomes, particularly severe critical events (SCEs), are scarce in Asia. This highlights the need for standardized research to assess anesthesia safety and quality in the diverse settings.AimsThe PEACH in Asia pilot study aimed to test the feasibility of a standardized protocol for investigating SCEs in anesthesia practices across Asia, evaluate the data acquisition processes, and determine the sample size for a main study.MethodsThis multicenter pilot study involved ten institutions across nine Asian countries, including children from birth to 15 years undergoing diagnostic or surgical procedures. Data on SCEs were collected using standardized definitions. The study assessed the feasibility and estimated the sample size needed for the main study.ResultsThe pilot study enrolled 330 patients, with a SCE incidence of 12.4% (95% CI: 9.2–16.4%). Respiratory events were observed in 7.0% of cases, cardiovascular instability in 4.9%, and drug errors in 0.6%. Based on the SCE incidence observed in the pilot study, the estimated sample size required for the main study is at least 10 958 patients. The pilot study demonstrated the feasibility of the study protocol but identified several challenges, particularly in resource‐limited settings. These challenges included a significant burden associated with data collection, technical issues with electronic case report forms (e‐CRFs), variability in patient enrollment across institutions (ranging from 4 to 86 patients per site), and incomplete data acquisition (24.8% of height data and 9.7% of disposition data were missing).ConclusionsThe PEACH in Asia pilot study successfully validated a protocol for investigating SCEs in pediatric anesthesia across Asia. Addressing the challenges identified in the pilot study will be crucial for generating robust data to improve pediatric anesthesia safety in the region. Key issues to address include improving data collection methods, resolving e‐CRF technical difficulties, and ensuring consistent institutional support.
Making peace with the past? Applying theater to asylum seekers' trauma
Authors: Majid Asif 
Published: November 2024

AbstractAsylum seekers—by virtue of their political and bureaucratically structured social positions—carry, negotiate, and rehash traumatic pasts. These pasts are, often, the main way through which they are understood in public and scholarly imagination. Yet, as the author's work of making theater with a group of Washington, DC‐based asylum seekers shows, making peace with the past is less about understanding and packaging traumas endured and more about imagining and envisioning alternate futures. Drawing examples from theater workshops and interviews conducted with asylum seekers, in which the past featured centrally, this essay considers the intersection of peace and art by examining the role of past traumas in imagining alternate futures despite the uncertainty of the present. In so doing, this essay questions public and scholarly narratives that position the figure of the asylum seeker as solely beholden to traumatic pasts, exactly because being compelled to (re)tell one's story to acquire residency and citizenship documentation is a task that is firmly oriented toward the future.
Unlocking the Promise of Liver Perfusion Technologies for Pediatric Transplantation: A State‐of‐the‐Art Review
Authors: Brown Cole S. , van Leeuwen L. Leonie , Akhtar M. Zeeshan , DiNorcia Joseph 
Published: November 2024

ABSTRACTBackgroundOutcomes after pediatric liver transplantation are generally excellent, but the limited avavailability of suitable, size‐matched liver allografts remains a significant barrier. Machine perfusion technology has emerged as a promising approach to expand the donor pool, enabling the use of less ideal whole liver grafts, such as livers donated after circulatory death, and enhancing the execution of split liver transplantation.MethodsThis review examines the application of machine perfusion in pediatric liver transplantation, focusing on two primary techniques: hypothermic oxygentaed perfusion and normothermic machine perfusion. These methods optimize storage, resuscitation, and assessment of liver grafts before transplantation, potentially expanding the range of usable donor organs.ResultsThe use of machine perfusion allows for the consideration of suboptimal donor livers and facilitates split liver transplantation, both of which could increase organ availability for pediatric patients. Implementation of machine perfusion could also help reduce waiting list mortality by enabling the safe use of a broader spectrum of donor organs.ConclusionsAdoption of machine perfusion in pediatric liver transplantation will require collaborative, multidisciplinary efforts across transplant centers. By fostering cooperative learning and sharing resources. the integration of machine perfusion into clinical practice has the potential to reduce mortality among children awaiting liver transplantation.
Decoding derogation: The impact of environmental values and political ideology on the effect of persuasive message about recycle and reuse behaviors
Authors: Shah Prerna , Yang Janet Z. 
Published: November 2024

AbstractAlthough persuasive messages are designed to motivate individuals to engage in intended behaviors, they do not always work. Often, people follow previously established values and ideologies and dismiss persuasive messages. We examine how participants react to a persuasive message related to plastic pollution and how these reactions shape their willingness to recycle and reuse. Results indicate that environmental values and political ideology are associated with message derogation in distinct ways, which, in turn, affect risk perception, self‐efficacy, and intention to recycle and reuse. Further, past behavior moderates the relationship between message derogation and perceived risk, but not the relationship between message derogation and self‐efficacy. These results suggest that pre‐existing values and ideologies play an important role in message derogation, a hitherto under‐researched phenomenon that has key implications for self‐reported behavioral change. Moreover, past behavior could serve as a powerful lever in steering risk perception and behavioral intent.
Effective warm‐ups in the German‐language classroom: Form and function
Authors: Ross Braden Marie 
Published: November 2024

AbstractThis article explores three questions developed to be central to the creation and implementation of an effective classroom warm‐up: Does it help jumpstart students’ use of German? Can it capture students’ attention? And does it encourage building rapport through providing opportunities for personal expression or relevance? Based on my experience as an instructor for the first and second semesters of the German language sequence at the University of Illinois at Urbana‐Champaign, I argue that a well‐constructed warm‐up in a German language course is more than a low stakes invitation to cultivate a mindset conducive to the demands of language learning; it is an opportunity to begin learning from a place of genuine interest, trust, and confidence. By implementing warm‐ups with the guidelines outlined in this article in mind, mnemonically referred to as JARR (Jumpstarting language use, capturing Attention, and building Rapport through Relevance) warm‐ups, instructors can set students up for success not only for the next hour of learning, but also for their entire language journey—all in the first 5 minutes of class.
Graphemic Variation in Morphosyntactic Context: The Syllable u in Classic Maya Hieroglyphic Writing
Authors: Matsumoto Mallory E. 
Published: November 2024

AbstractThroughout the long history of Classic Maya hieroglyphs, a logosyllabic writing system used from the late first millennium BCE through the mid‐second millennium CE in southern Mesoamerica, the most commonly recorded phonetic value was the syllable u (/ʔu/). With over a dozen different u hieroglyphs, Classic Maya scribes had more options for recording /ʔu/ than any other syllable or logograph. Cognitive approaches to writing systems typically attribute graphemic variation (i.e., alternation between signs with equivalent linguistic value) to semantic differences like animacy or to non‐linguistic factors like identity. Distribution of Classic Maya u hieroglyphs, however, suggests that morphosyntactic context influenced which grapheme scribes wrote and when. This case suggests that scribal knowledge of Classic Maya hieroglyphs included ideas about writing's relationship to language. It also highlights the cognitive relevance of morphosyntax for a writing system's users as they differentiate among graphic signs with identical linguistic denotation.
Characterisation and Sensitivity of a Canine Mast Cell Tumour Line to Oncolytic Viruses
Authors: Mehrani Yeganeh , Kakish Julia E. , Napoleoni Christina , Thompson Jennifer Jane , Knapp Jason P. , Minott Jessica A. , Yates Jacob G. E. , Stuart Deirdre , Coomber Brenda L. , Foster Robert A. , Bridle Byram W. , Karimi Khalil 
Published: November 2024

ABSTRACTCanine mast cell tumours (MCTs) are one of the most common skin cancers of dogs. Surgical removal is the primary treatment, but recurrence and metastasis can occur even with low‐grade tumours. As a result, new treatment strategies are being sought. We tested the potential of several oncolytic viruses (OVs) to infect and kill a cell line isolated from a canine MCT. Employing a resazurin‐based metabolic assay and flow cytometry technology, we used recombinant vesicular stomatitis virus (rVSV‐Δm51), avian orthoavulavirus‐1 (AOaV‐1), and Orf viruses in our assessment. Our study aimed to evaluate the potential of oncolytic virotherapy in treating canine cancers. We found that MCT‐1 cells showed different sensitivities to the OVs, with rVSV‐Δm51 showing the most promising results in vitro. These findings suggest that further investigation into using OVs for treating canine MCTs is needed, although clinical efficacy is yet to be determined.
Annual Prize Lecture 2024: Endogenous physiological mechanisms as basis for the treatment of obesity and type 2 diabetes
Authors: Holst Jens Juul 
Published: November 2024

AbstractIn 1964, it was proven that postprandial insulin secretion is largely regulated by gut hormones and, in 1973, it was proposed that a gut hormone would also regulate appetite and food intake. Several gut hormones were tested for metabolic actions with disappointing results until the discovery of the proglucagon derivative, glucagon‐like peptide‐1 (GLP‐1). This peptide from the distal intestine has preserved activity on insulin secretion in people with type 2 diabetes and turned out to regulate both secretion and motility in the gastrointestinal tract and importantly, appetite and food intake, thus functioning as an efficient ‘ileal brake’ hormone. However, the natural hormone acts predominantly via sensory afferent systems and is extremely rapidly removed from the circulation by enzymatic degradation and renal elimination, and increasing the doses merely results in nausea and vomiting. Lipidation of analogs turned out to provide both stability and limit renal elimination, and very slow up‐titration of dosing improves tolerance. Indeed, the most recent agonists may near‐normalize glycaemic control in type 2 diabetes, may cause weight losses of up to 25% of body weight, and significantly reduce cardiovascular risk, effects that resemble those of bariatric surgery. Thus, a solution to one of the most serious health problems of modern civilization, the increased morbidity and mortality of the metabolic syndrome, may be addressed by mobilization of one of the body's own regulatory mechanisms.
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Effect of Compressive Strain Rates on Viscoelasticity and Water Content in Intact Porcine Stomach Wall Tissues
Authors: Udayamohan Vijay Shashank , Byju Achu Geetha , Harris Jason L. , Haridas Balakrishna 
Published: November 2024

Abstract
Laparoscopic staplers are used extensively to seal and transect tissue. These devices compress tissue between the stapler jaws to achieve a desired compressed tissue thickness in preparation for stapling. The extent and rate of compression are dependent on surgeon technique, tissue characteristics, and stapler type, all of which can impact stapling outcomes such as bleeding, staple line leaks, and tissue healing. Historically, surgeons have relied on their experience, training, and tactile feedback from the device to optimize stapling. In recent years, the transition to electromechanical and robotic staplers has greatly impacted the tactile feedback available to the surgeon. This raises new questions about the optimal rates of tissue compression and the resultant tissue forces. This study quantifies the transmural biomechanics of the porcine stomach wall. Multirate indentation tests were used to observe the effects of indentation rate on the viscoelastic behavior of the stomach tissue during indentation, stress relaxation, and unconstrained recovery. Results show that the stomach wall demonstrates higher stress relaxation (88% versus 80%) and greater strain recovery (52% versus 47%) when indented at high rates (37.5%/s) versus slow rates (7.5%/s). Additionally, water content analysis was used to study fluid flow away from indented regions. Unindented regions were found to have greater water content compared to indented regions (78% compared to 75%). This data generated in this study may be used to enable the development of constitutive models of stomach tissue, which in turn may inform the control algorithms that drive compressive surgical devices.
Structural Integrity Evaluation of Three-Dimensional-Printed Graphene-Reinforced Polylactic Acid Notched Plates Using Failure Assessment Diagrams
Authors: Cicero Sergio , Arrieta Sergio , Sanchez Marcos 
Published: November 2024

Abstract
Failure assessment diagrams (FADs) constitute a well-known structural integrity evaluation tool that allows structural components containing crack-like defects to be assessed through a simultaneous analysis of fracture and plastic-collapse processes. FADs are included in the most recognized structural integrity assessment procedures/standards, such as BS7910 and API 579/ASME FFS-1, and their use is generally limited to metallic components containing crack-like defects. On the other hand, structural responsibilities are being assumed by three-dimensional-printed composites, and particularly by those obtained through FFF (fused filament fabrication), beyond their most extended use as prototyping materials. The resulting structural components may contain notch-type defects (e.g., grooves, corners, holes) that determine their corresponding structural integrity. Thus, it is necessary to define structural integrity assessment criteria for this kind of materials when containing any kind of stress risers, beyond crack-like defects. This work justifies the use of BS7910 Level 1 FAD, coupled with a notch correction derived from the theory of critical distances (TCD), to analyze graphene-reinforced polylactic acid (PLA) plates subjected to pure tensile loading conditions and containing U- and V-notches. The results reveal that, for U- and V-notches, the assessment points representing the plates at failure are located within the FAD area corresponding to unsafe conditions, providing conservative evaluations with moderate safety margins. For plates containing circular holes, the proposed approach provides unsafe predictions.
Effect of Various Notch Shapes on Lamb Wave Scattering Behavior in a Bent Plate
Authors: Tembhare Girish U. , Joglekar D. M. 
Published: November 2024

Abstract
The application of guided waves to investigate commonly used plate shapes in the aerospace, mechanical, and civil industries is plates with bend shapes. This article investigates the interaction of fundamental Lamb waves with notches in bent plates, commonly found in aerospace, mechanical, and civil engineering applications. These areas are particularly susceptible to failure due to defects such as cracks and notches, which often manifest as semicircular corrosion patches or 90-deg notches. The presence of notches affects stress distribution, necessitating thorough analysis to prevent accidents. Accordingly, this article focuses on the interaction of fundamental Lamb waves through two types of notches that could be present inside a bent metal plate section. To explore this, a hybrid numerical framework is employed which combines semianalytical finite elements (SAFEs) with the finite element method (FEM). A bent plate section with various notch types is simulated using FEM, while SAFEs facilitate the definition of wave propagation through healthy regions of the plate. The study analyzes the scattering behavior of Lamb waves for different notch configurations and examines both fundamental modes over a specified frequency range. With a change in the interrogation signal parameters, there is a noticeable difference in the sensitivity of scattered waves with different notch types. Formulating a strategy for identifying and locating a notch inside a bent plate may need careful consideration of the important conclusions drawn. Understanding these interactions, the aim of the article is to enhance the integrity assessment of structural components subject to such defects.
Irradiation Damage Evolution Dependence on Misorientation Angle for Σ 5 Grain Boundary of Nb: An Atomistic Simulation-Based Study
Authors: Manna Mouparna , Pal Snehanshu 
Published: November 2024

Abstract
Niobium as refractory element holds ability to arrest the primary radiation damage in reactor's fissionable conditions and can withstand high-temperature applications. We have inclined the investigation of irradiated Nb Σ 5 symmetric-tilt angled grain boundary (STGB) models at two high-angled grain boundary misorientation: 53.13 deg (Σ 5(2–10)/(120)) and 36.87 deg (Σ 5(3–10)/(130)), respectively. A hybrid of Ziegler–Biersack–Littmark (ZBL) and embedded atom method (EAM) potentials were superimposed to simulate radiation damage. Statistical averaging of the displacement cascades was conducted to study the dynamic evolution of the point defects and interstitial clusters at varying magnitudes of primary knock-on atom (PKA) energies, irradiation temperatures, and PKA directions. The irradiated grain bounary (GB) models were compared with an irradiated bulk Nb specimen, and the results of the study indicate that the irradiated Nb system with greater misorientation angle, i.e., Nb Σ 5 (ɵ = 53.13 deg) survived with lower number Frenkel pair defects as well as the population small-sized interstitial clusters. The point defect cluster analysis indicated the highest population of interstitial clusters survived in Nb STGB models were irradiated along &lt;1 3 5&gt; PKA direction and 100 keV recoil energies respectively.
Patient Perceptions of Psychological and Rehabilitation Experiences After Anterior Cruciate Ligament Reconstruction: A Qualitative Study
Authors: Murray Megan , Wekesser Meredith , DeFreese J.D. , Kuenze Christopher , Brinkman Caitlin , Gould Daniel , Baez Shelby 
Published: November 2024

Context: Over 80% of patients anticipate fully returning to sport (RTS) within 1 year after anterior cruciate ligament reconstruction (ACLR), but only one quarter of patients succeed. Although several factors influence the RTS process, this study focused on how psychological responses to injury, such as injury-related fear and self-determined motivation, help to explain variation in rehabilitation experiences. There is limited information about how these meaningful psychological responses to injury are connected to responses such as athlete burnout or how patient perceptions of these responses relate to rehabilitation. The purpose of this qualitative study was to explore how patient perceptions of injury-related fear, self-determined motivation, and athlete burnout influence individual psychological and rehabilitation experiences at 4 to 6 months post-ACLR. Design: Qualitative study. Methods: Eight patients (female = 4, age = 16.3 ± 1.9) between 4 and 6 months post-ACLR who injured their knee playing or training for sports were included in the study. Patients completed the Sport Motivation Scale-6, Athlete Burnout Questionnaire, Perceived Stress Scale 4, and Tampa Scale of Kinesiophobia-11 to measure self-determined motivation, athlete burnout, stress, and injury fear. These questionnaires collected descriptive data used to guide audio- and video-recorded semistructured interviews. The interviews were transcribed and analyzed in a 6-stage process of thematic analysis. Results: Thematic analysis revealed 3 themes related to how participants perceived their rehabilitation experiences: (1) acknowledging recurring struggles during recovery, (2) finding motivation to RTS and normal life, and (3) successfully navigating the recovery process. In particular, participants described the impact of positive shifts in their psychological perceptions at 4 to 6 months post-ACLR. Conclusions: Patients 4 to 6 months post-ACLR described how struggles during their recovery and rehabilitation experiences were improved by positive shifts in their psychological perceptions. Increasing positive psychological awareness within a supportive rehabilitation environment may improve rehabilitation experiences and RTS rates after ACLR.
Complete genome of
Variovorax
sp. EBFNA2, isolated from a surface-sterilized fava bean nodule
Authors: Hirsch Ann M. , Humm Ethan , Rubbi Liudmilla , Del Vecchio Giorgia , Ha Sung Min , Pellegrini Matteo , Gunsalus Robert P. 
Published: November 2024

ABSTRACT

We report the complete genome sequence of
Variovorax
sp. EBFNA2, a fava bean nodule endophyte. The strain appears to be a new species, and its genome provides insight into its interactions with host plants and potential to promote plant growth and crop yield.