bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wild tomato endosperm transcriptomes reveal common roles of genomic imprinting in both nuclear and cellular endosperm
Authors: Roth Morgane , Florez‐Rueda Ana M. , Paris Margot , Städler Thomas 
Published: June 2018

SummaryGenomic imprinting is a conspicuous feature of the endosperm, a triploid tissue nurturing the embryo and synchronizing angiosperm seed development. An unknown subset of imprinted genes (IGs) is critical for successful seed development and should have highly conserved functions. Recent genome‐wide studies have found limited conservation of IGs among distantly related species, but there is a paucity of data from closely related lineages. Moreover, most studies focused on model plants with nuclear endosperm development, and comparisons with properties of IGs in cellular‐type endosperm development are lacking. Using laser‐assisted microdissection, we characterized parent‐specific expression in the cellular endosperm of three wild tomato lineages (Solanum section Lycopersicon). We identified 1025 candidate IGs and 167 with putative homologs previously identified as imprinted in distantly related taxa with nuclear‐type endosperm. Forty‐two maternally expressed genes (MEGs) and 17 paternally expressed genes (PEGs) exhibited conserved imprinting status across all three lineages, but differences in power to assess imprinted expression imply that the actual degree of conservation might be higher than that directly estimated (20.7% for PEGs and 10.4% for MEGs). Regardless, the level of shared imprinting status was higher for PEGs than for MEGs, indicating dissimilar evolutionary trajectories. Expression‐level data suggest distinct epigenetic modulation of MEGs and PEGs, and gene ontology analyses revealed MEGs and PEGs to be enriched for different functions. Importantly, our data provide evidence that MEGs and PEGs interact in modulating both gene expression and the endosperm cell cycle, and uncovered conserved cellular functions of IGs uniting taxa with cellular‐ and nuclear‐type endosperm.
Evaluation of a prognostic scoring system for dogs managed with hemodialysis
Authors: Perondi Francesca , Lippi Ilaria , Ceccherini Gianila , Marchetti Veronica , Bernicchi Lucrezia , Guidi Grazia 
Published: June 2018

AbstractObjectiveTo investigate prognostic models in a cohort of dogs with acute kidney injury (AKI) and acute on chronic kidney disease (AKI/CKD) managed by hemodialysis.DesignRetrospective study from July 2011 to November 2014.SettingUniversity Veterinary Teaching Hospital.AnimalsForty dogs with historical, clinical, imaging, and laboratory findings consistent with AKI or AKI/CKD managed with intermittent hemodialysis were included.InterventionsScoring system models previously established by Segev et al for outcome prediction in dogs with AKI were applied to all dogs.ResultsModels A, B, and C correctly classified outcomes in 68%, 83%, and 85% of cases, respectively. In our cohort Model A showed sensitivity of 58% and specificity of 86%, Model B showed sensitivity of 79% and specificity of 87%, Model C showed sensitivity of 86% and specificity of 84%. The presence of anuria (P< 0.0002), respiratory complications (P< 0.0001), disseminated intravascular coagulation (DIC) (P= 0.0004), grade of AKI (P= 0.0023), pancreatitis (P= 0.0001), and systemic inflammatory response syndrome (SIRS) (P= 0.0001) was significantly higher in nonsurvivors compared with survivors.ConclusionsIn our cohort of patients, Segev's model C showed the best sensitivity and specificity for predicting prognosis, while model A had lower sensitivity. In our cohort of dialysis patients, the presence of respiratory complications, DIC, SIRS, and pancreatitis at hospitalization, were correlated with a poor prognosis.
Lived experience of Silver-Russell syndrome: implications for management during childhood and into adulthood
Authors: Ballard Lisa Marie , Jenkinson Elizabeth , Byrne Christopher D , Child Jenny C , Davies Justin Huw , Inskip Hazel , Lokulo-Sodipe Oluwakemi , Mackay Deborah J G , Wakeling Emma L , Temple I Karen , Fenwick Angela 
Published: June 2018

ObjectiveThere is limited information on the psychosocial impact of growing up with Silver-Russell syndrome (SRS), characterised by slow growth in utero leading to short stature in adulthood. Such information could aid families in making difficult treatment decisions and guide management strategies for health professionals. We aimed to explore the lived experience of people with SRS across the lifespan.Design/setting/patientsIn-depth, semi-structured interviews were conducted between January 2015 and October 2016 with a sample of 15 adults (six women) with genetically confirmed SRS from the UK. Qualitative interviews were transcribed and coded to identify similarities and differences: codes were then grouped to form overarching themes.ResultsFour themes were identified from participant accounts: (1) appearance-related concerns extending beyond height; (2) strategies to deal with real and perceived threats; (3) women’s experiences of pain, disability and feeling older than their years; and (4) feeling overlooked in romantic relationships. These themes show that other factors, beyond short stature, affect patient well-being and indicate a mismatch between patient need and healthcare provision.ConclusionsChallenges in SRS during childhood and adolescence were central to the psychosocial impact of SRS, and were not limited to height. These challenges, as well as symptoms such as pain and fatigue for women, have not previously been documented. To help individuals with SRS develop strategies to manage psychosocial issues, we recommend clinicians incorporate psychological services as an integral part of multidisciplinary teams managing individuals with SRS during childhood, adolescence and adulthood.
Prevalence, Predictors, and Prognostic Value of Residual Tricuspid Regurgitation in Patients With Left Ventricular Assist Device
Authors: Nakanishi Koki , Homma Shunichi , Han Jiho , Takayama Hiroo , Colombo Paolo C. , Yuzefpolskaya Melana , Garan Arthur R. , Farr Maryjane A. , Kurlansky Paul , Di Tullio Marco R. , Naka Yoshifumi , Takeda Koji 
Published: June 2018

Background

Although implantation of a left ventricular assist device (
LVAD
) generally improves tricuspid regurgitation (
TR
) in short‐term follow‐up, the clinical significance of residual
TR
in patients with mid‐ to long‐term
LVAD
support is unknown. This study aimed to identify the prevalence, predictors, and prognostic value of residual
TR
in
LVAD
patients in association with tricuspid valve (
TV
) deformation.

Methods and Results

The study cohort consisted of 127 patients who underwent
LVAD
implantation without
TV
procedure and were supported with
LVAD
at least 1 year. All patients underwent echocardiographic examination preoperatively and 1 year after
LVAD
implantation.
TR
was quantitatively assessed by ratio of
TR
color jet area/right atrial area, and significant residual
TR
was defined as ≥20% of %
TR
at follow‐up echocardiographic examination. Detailed echocardiographic measurements were also performed, including
TV
annulus diameter,
TV
leaflet displacement, and left ventricular and right ventricular systolic function.
LVAD
implantation significantly improved ratio of
TR
color jet area/right atrial area as well as left ventricular and right ventricular systolic function and tethering distance (all
P
<0.05), whereas it enlarged
TV
annulus diameter (
P
=0.002). Significant residual
TR
was observed in 30 (23.6%) patients. Age, preoperative
TV
annulus diameter, and residual mitral regurgitation were significantly associated with significant residual
TR
(all
P
<0.05), whereas
TV
tethering was not. During a mean follow‐up of 21±17 months, patients with residual
TR
had significantly higher mortality than those without residual
TR
(log‐rank
P
<0.001).

Conclusions

Significant residual
TR
was observed in ≈25% patients supported with
LVAD
over 1 year and was associated with unfavorable outcome.
Reviews
Authors: Ferrer Sergi , Amestoy Susana Domingo , Muñoz Lindsey Reuben 
Published: June 2018

Abstract
Why Minority Governments Work. Multilevel Territorial Politics in Spain, Bonnie N. Field (2016) New York: Palgrave Macmillan, 261 pp., ISBN: 978 1 137 55979 1, h/bk, 978 1 137 55980 7, e-pdf, $119.99, $89
The Ghost in the Constitution: Historical Memory and Denial in Spanish Society, Contemporary Hispanic and Lusophone Cultures, vol. 15, Joan Ramon Resina (2017) Liverpool: Liverpool University Press, 322 pp., ISBN: 9781786940223, h/bk, £85.00
Literature of Crisis: Spain’s Engagement with Liquid Capital, Olga Bezhanova (2017) Lewisburg: Bucknell University Press, 175 pp., ISBN: 978-1611488364, hbk, $90.00
Forecasting the Ecology Effects of Electric Cars Deployment in Krasnodar Region: Learning Curves Approach
Authors: RATNER Svetlana , ZARETSKAYA Marina 
Published: June 2018

One of the most urgent problems of modern urban agglomerations is the optimization of the structure and technological maintenance of transport systems. As one of the options to solve this problem, the development of electric vehicles (EV) is usually suggested. But the scientific community has still not developed a clear understanding of whether electric vehicles are a better alternative to traditional cars, considering all environmental indicators. The aim of this work is to develop a method of forecasting the environmental effects of diffusion of EV technologies and test it on the example of the Krasnodar region of Russia as a region with the highest motorization ratios in the country, a complicated ecologic situation in large cities, a high population density and a modern structure for energy generation. The technical progress in energy efficiency of each technology is taken into consideration. We use learning theory as a methodological framework, which is common for solution of problems of forecasting technological development. According to the calculations, the total emissions from private motor vehicles, with an increase in energy efficiency of vehicles with internal combustion engine and increase penetration of electric vehicles should decrease in 2025 by 15% comparing business-as-usual scenario, despite a significant increase in the level of motorization (almost 65%). Thus, a wide spread of EV technologies is preferable from an environmental point of view. The proposed approach to predict the environmental effects of diffusion of EV technologies allows us to estimate the reduction in emissions from road transport in any region while maintaining the direction and speed of the following key trends: the growth of energy efficiency and environmental performance of traditional cars with combustion engines, the growth of the level of motorization of the population in Russia, and reduction of EVs costs. Additional effects of stimulating (or de-stimulating) policies are not considered in this model.
Potensi Ekosistem Mangrove Sebagai Sumber Bakteri Untuk Produksi Protease, Amilase Dan Selulase
Authors: Subagiyo Subagiyo , Djarod Muhammad Salauddin Ramadhan , Setyati Wilis Ari 
Published: June 2018

The mangrove ecosystem is a productive ecosystem. The production and accumulation of organic matter on the floor of the mangrove ecosystem allows this region to be rich in microbials that are potential to be developed as a source of a wide range of extra cellular enzymes. In this research, bacteria were isolated and used as the source of enzyme. The bacteria were isolated from the existing mangrove sediments on the north coast of Semarang, Central Java. The bacterial potential as a source of protease, amylase and cellulase is done semiquantitatively using well diffusion agar method. The results obtained 18 bacteria isolates which were all capable to produce amylase and cellulase, but only 7 isolates were able to produce proteases. Five isolates had amylase activity above 300 mm2 / ml, three isolates with protease activity above 300 mm2 / ml and 2 isolates with cellulase activity of 225.40 and 204.50 mm2 / ml. Seven isolates are capable of producing amylase, protease and cellulase. The results showed that mangrove ecosystem is a potential source of microbes to produce enzymes protaese, amylase and cellulase and also possible for various other extracellular enzymes. Keyword : bacteria, mangrove, protease, amylase, celluloseEkosistem mangrove merupakan ekosistem produktif. Produksi dan akumulasi bahan organik di lantai ekosistem mangrove memungkinkan daerah ini kaya akan mikrobia yang potensial untuk dikembangkan sebagai sumber berbagai macam enzim ekstra seluler. Pada penelitian ini dilakukan isolasi bakteri sebagai sumber enzim. Bakteri diisolasi dari sedimen mangrove yang ada di pantai Utara Semarang, Jawa Tengah. Pengujian potensi bakteri ini sebagai sumber protease, amilase dan selulase dilakukan secara semikuantitatif menggunakan metode well diffusion agar. Hasil penelitian mendapatkan 18 isolat bakteri yang seluruhnya mampu memproduksi amylase dan selulase, tetapi hanya 7 isolat yang mampu memproduksi protease. Lima isolat memiliki aktivitas amylase diatas 300 mm2/ml, tiga isolat dengan aktivitas protease diatas 300 mm2/ml dan 2 isolat dengan aktivitas selulase yaitu sebesar 225,40 dan 204,50 mm2/ml. Tujuh isolat yang mampu menghasilkan amylase, protease dan selulase. Hasil penelitian menunjukkan bahwa ekosistem mangrove merupakan sumber potensial mikrobia untuk menghasilkan enzim protaese, amylase dan selulase serta juga dimungkinkan untuk berbagai macam ensim ekstraseluler lainnya. Kata kunci : bakteri, mangrove, protease, amylase dan selulase
Bakteri Simbion Karang Lunak Sinularia sp. sebagai Agen Antibakteri
Authors: Widyaningsih Sekar , Sa’adah Nor 
Published: June 2018

Abstract Symbiotic bacteria of soft-coral Sinularia sp. as antibacterial agentThe disease caused by bacterial pathogen infection has become a major problem in the world of health. Therefore, it needs new bioactive compond to resolve that problem. Symbiotic bacteria of softcoral are one promising source. This is because symbiotic bacteria of softcoral have the same bioactive compounds as their host. Symbiotic bacteria were isolated from softcoral Sinularia sp. that collected from Tanjung Gelam Waters, Karimunjawa Jepara. The symbiotic bacteria screened for antibacterial activity against E.coli, Proteus sp., Enterobacter sp. and S. aureus with diffution agar method. One of ten symbiotic bacteria was active against, SNTGA 5, with inhibition zone 9.067 ± 0.305 mm against E coli, 8.533 ± 0.416 mm against S. aureus, 9.067 ± 0.058 mm against Enterobacter sp., dan 9.1± 0.557 mm against Proteus sp.. The molecular identification based on partial 16S DNA, that active isolate was closely related to Pseudomonas stutzeri.Keywords: Antibacterial, Sinularia sp., symbiontic bacterial, PCR 16S DNA, Pseudomonas stutzeri Abstrak Penyakit akibat infeksi bakteri patogen telah menjadi masalah utama dalam dunia kesehatan. Oleh karenanya, diperlukan bahan aktif baru guna mengatasi masalah tersebut. Bakteri simbion karang lunak merupakan salah satu sumber yang menjanjikan. Hal ini karena bakteri simbion karang lunak memiliki senyawa bioaktif yang sama dengan inangnya. Bakteri simbion diisolasi dari karang lunak Sinularia sp. yang dikoleksi dari Perairan Tanjung Gelam Karimunjawa Jepara. Bakteri simbion diuji aktivitasnya terhadap E.coli, Proteus sp., Enterobacter sp. dan S. aureus dengan metode difusi agar. Satu dari 10 bakteri simbion memiliki aktivitas antibakteri, SNTGA5, dengan besar zona hambat 9.067 ± 0.305 mm terhadap E coli, 8.533 ± 0.416 mm terhadap S. aureus, 9.067 ± 0.058 mm terhadap Enterobacter sp., dan 9.1± 0.557 mm terhadap Proteus sp.. Identifikasi molekuler dilakukan dengan menggunakan PCR 16S DNA, dimana isolat yang aktif memiliki memiliki kekerabatan terdekat dengan Pseudomonas stutzeri.Kata kunci : Antibakteri, Sinularia sp., PCR 16S DNA, Pseudomonas stutzeri
Why is the hydrolytic activity of acetylcholinesterase pH dependent? Kinetic study of acetylcholine and acetylthiocholine hydrolysis catalyzed by acetylcholinesterase from electric eel
Authors: Komersová Alena , Kovářová Markéta , Komers Karel , Lochař Václav , Čegan Alexander 
Published: June 2018

Abstract
The dependence of the activity of acetylcholinesterase from electric eel at a pH value range of 4.8–9.8 (phosphate buffer), regarding acetylcholine and acetylthiocholine hydrolysis, was determined at 25 °C, ionic strength of 0.11 M, and initial substrate concentration of 4 mM. At a pH range of 4.8–9.8, the dependences A(pH) form a sigmoid increasing curve with the maximum catalytic activity at a pH range 8–9.5. For acetylcholine hydrolysis, the kinetic reason for such an increase in A consists mainly of an increase in the rate constant k
2 (Michaelis-Menten) model with increasing pH of the reaction mixture. For acetylthiocholine hydrolysis, the kinetic explication of the determined dependence A(pH) is more complicated.
Cultural ideals: Changes in patterns of knowledge (from the point of view of reading history)
Authors: Monok István 
Published: June 2018

The present study started out by posing the question: what reasons might lead to the success of Hungarian intellectuals who were schooled in Hungary and who later emigrated to the West. From among the possible answers, we examined one: education and reading culture in Hungary was more complex in a given period than in Western Europe. We consider whether or not this answer is persuasive.
Based on the results provided by basic research in reading history in Hungary in the early modern period, one can safely say that the culture of experts in Hungary was more heterogeneous, and these experts constantly revisited traditional sources and kept them alive. On the other hand, in terms of the depth of professional knowledge and the level of concentration on a given field they were lagging behind their contemporary colleagues in Western Europe. This situation produced a dual eff ect: experts in Hungary had a stronger sense of tradition and they looked for transitional solutions due to the lack of the latest technical development and literature. Out of the Hungarian context, however, they produced outstanding achievements thanks to the more heterogeneous nature of their expertise.
„New classicism” and the music of „new humanity” – Hungarian music historiography and Bence Szabolcsi
Authors: Rákai Zsuzsa 
Published: June 2018

Hungarian music historiography traditionally regards the dispute about „new Hungarian music” as a contest between conservative and progressive aesthetic views. However, the artistic problem of the Hungarian intelligentsia in the interwar period were more complex. They had tasks such as synchronizing modernism and nationalism, harmonising 19th century ideals and 20th century compositional ideas and redefining the criteria of the national musical-cultural canon.
The musicologist Bence Szabolcsi created an influential theory on peasant music inspired symphonic style already in the 1920s. He supported Kodály in his articles and he had a conscious intention to establish a new school of Hungarian music. As a young man Szabolcsi created a future oriented golden age theory based on his belief that the classical era was the absolute peak of European music. He made a diff erence between artistic creation (as a reflection of divine creation) and consciuos composition, classicism and romanticism, culture and civilization, and he regarded the latter categories as the signs of perilous European decadence from which there is no other choice but a „new classicism”, that is a „new testament”. Young Szabolcsi thought „new Hungarian music” could be the new and only path leading back to God, to culture, to music.
Relationship between students’ performance on weekly task assessments and final practical exam at the preclinical restorative dentistry course
Authors: Ayar Muhammet Kerim 
Published: June 2018

Objectives: The purpose of this study was to examine the relationships between dental students’ performance on weekly practical task assessments, midterm practical exam and final practical exam in the preclinical restorative dentistry course. Methods: Scores of final practical exam, midterm practical exam and weekly practical task assessments in the restorative dentistry preclinical course in the half year of the third year of the curriculum at Biruni University Faculty of Dentistry were compared. It was hypothesized that students that performed highly on weekly task assessments would perform highly on the midterm and final practical exams. Results: The results showed that the weekly practical task assessment scores were correlated with the midterm practical exam and final practical exam scores and were a positive predictor. However, final practical exam scores were significantly lower than midterm practical exam and weekly practical task assessment scores. Conclusions: The quality assessments of students’ weekly tasks would be an effective predictor to assess student’s preclinical performance. Thus, it would be recommended that integrating weekly task assessment into the preclinical restorative dentistry curriculum as an effective assessment tool.
LOS REPERTORIOS VISUALES EN LA EDUCACIÓN ARTÍSTICA. HISTORIA DEL ARTE, CULTURA VISUAL GLOBAL Y CURRICULUM EN LAS COLECCIONES VISUALES DE DOCENTES ARGENTINOS
Authors: Carola Corbetta , Dussel Inés 
Published: June 2018

¿Qué imágenes usan los docentes de educación artística para enseñar? En una encuesta a profesores de escuelas secundarias de Buenos Aires (Argentina), se vio que su elección combina criterios de las tradiciones didácticas de la materia, los nuevos “esperantos visuales globales” y las demandas pedagógicas del contexto actual. Las imágenes más elegidas fueron, en orden de importancia, pinturas de las vanguardias del siglo XX o del Renacimiento, que muestran la continuidad con la tradición disciplinaria; también aparecen imágenes del pop-art y “ready-made” como base para la intervención digital; mandalas para colorear, no solamente por su valor estético sino por su valor disciplinario, “pacificador”, en las aulas; y arte efímero y participativo realizado con intervenciones. Estos repertorios visuales constituyen un curriculum no escrito y no problematizado de la educación artística. El trabajo se basa en los estudios visuales (Mirzoeff, Groys y Pollock) y en la sociología histórica del curriculum (Bernstein, Popkewitz) que considera al conocimiento escolar como un andamiaje de discursos y temporalidades múltiples.
Sistem Pengendali Inventori Supply Chain Dengan Pendekatan Probabilitas Pada Industri Pakaian
Authors: . Mustafid , Sabila Alzena Dona , . Suryono 
Published: June 2018

Inventory control systems have an important role in supply chain management to control process of production, inventory and distribution of products in accordance with rapidly changing consumer demand. The research aims to develop inventory control system on supply chain that can manage the number of production and supply of products based on variables of consumer demand and lead time. Supply chain inventory control systems are designed using model of supply chain inventory control within the information system framework. Model of inventory control using variable of demand lead time is designed by probability approach. Input to the system are data of demand and lead time sent by retail. The results of research provide theory of supply chain inventory control system with probability approach, especially on developing the theory of probability distribution for combined variables from two random variables of normal distributed. Inventory control system used to determine safety stock and reorder point as the basis for determining the replenishment stock. Furthermore by the system, supply chain management can manage the estimation of production number, and manage inventory and stock number of products in warehouse, supplier and retail in accordance with the consumer demand.