bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indigenous African Synchronicity for Revitalizing Adult Education for Positive Social Change
Authors: Avoseh Mejai 
Published: November 2024

The need for and the importance of education, especially adult learning and education (ALE) continues to increase across the world especially given the challenges of our world, hyper-technology and Artificial Intelligence (AI). The purpose of this paper is the critical issue of the humanistic perspective of education. The central question is: “to what extent do the universal rendering and practice of ALE representative of the world?” And “how fitting is this universal frame within the indigenous contexts?”. This paper offers the Indigenous African synchronized and holistic lifelong learning as a viable compliment to revitalize education for positive social change.

Sincronicità africana indigena per rivitalizzare l’educazione degli adulti e promuovere trasformazioni sociali positive.
La necessità e l’importanza dell’istruzione, in particolare dell’apprendimento e dell’istruzione degli adulti (ALE), continua a crescere in tutto il mondo, soprattutto date le sfide del nostro mondo, dell’ipertecnologia e dell’intelligenza artificiale (AI). Lo scopo di questo articolo è la questione critica della prospettiva umanistica dell’educazione. La domanda centrale è: “in che misura il rendering universale e la pratica dell’ALE sono rappresentativi del mondo?” E “quanto si adatta questa cornice universale ai contesti indigeni?”. Questo articolo propone l’apprendimento permanente sincronizzato e olistico degli indigeni africani come un valido complemento per rivitalizzare l’istruzione per un cambiamento sociale positivo.
Analyzing training needs of those working in the care of frail elderly: results of a preliminary exploratory research
Authors: Bruni Elisa , Ricci Aurora , Luppi Elena 
Published: November 2024

The literature highlights the need for innovation in the training of senior care professionals to enable them to respond to emerging challenges and provide services oriented towards the quality of life of older adults. The aim of the research is to explore the training needs of professionals in the care of frail older people, particularly in light of the Covid-19 experience, using an exploratory qualitative research design. Interviews and mini focus groups were conducted with 25 participants, and the data were analyzed using thematic analysis. The results suggest the need to promote caregivers’ social-emotional competencies and adopt person-centred approaches to ensure the professional well-being and quality of life of older persons.

Analizzare bisogni formativi di chi opera nella cura di anziani fragili: gli esiti di una prima ricerca esplorativa.
La letteratura sottolinea la necessità di innovare la formazione dei professionisti della cura della terza età, affinché siano in grado di rispondere alle sfide emergenti e fornire servizi orientati alla qualità della vita degli anziani. L’obiettivo della ricerca è quello di esplorare i bisogni formativi delle figure professionali della cura delle persone anziane fragili, anche alla luce dell’esperienza del Covid-19, adottando un disegno di ricerca qualitativo di tipo esplorativo. Sono state condotte interviste e mini focus group con 25 partecipanti e i dati sono stati analizzati con l’analisi tematica. I risultati suggeriscono la necessità di promuovere le competenze socio-emotive dei caregiver e di adottare approcci centrati sulla persona per garantire il benessere professionale e la qualità della vita degli anziani.
Learning Cities: Catalysts for Sustainable Urban Development through Collaborative Partnerships
Authors: Piazza Roberta 
Published: November 2024

This study explores the central role of learning cities in promoting sustainable urban development through collaborative partnerships. Based on the learning city model, this study emphasizes the importance of integrated strategies to improve community well-being. It examines the role of partnerships in addressing sustainability challenges, echoing the objectives of the Jean-Monnet SSIASDG network. Furthermore, it addresses the theme of social innovation and the interconnection between economic, political, and social spheres to foster change in cities. Despite persistent challenges such as institutional constraints and limited coordination, this study advocates a paradigm shift towards prioritizing the collective good. By promoting partnerships and embracing holistic problem solving, cities can become sustainable and resilient drivers, contributing to a more equitable future.

Learning Cities: Veicoli di sviluppo urbano sostenibile tramite partnership collaborative.
Il contributo esplora il ruolo centrale delle città che apprendono nel promuovere lo sviluppo urbano sostenibile attraverso partenariati collaborativi. Basandosi sul modello della learning city, il saggio sottolinea l’importanza delle strategie integrate per migliorare il benessere della comunità. Esamina il ruolo dei partenariati nell’affrontare le sfide della sostenibilità, facendo eco agli obiettivi della rete Jean Monnet SSIASDG. Inoltre, si sofferma sul concetto di innovazione sociale e dell’interconnessione tra sfera economica, politica e sociale per favorire il cambiamento nelle città. Nonostante le sfide persistenti, come i vincoli istituzionali e il coordinamento limitato, il documento sostiene la necessità del cambiamento di paradigma che dia priorità al bene collettivo. Promuovendo le partnership e abbracciando la soluzione olistica dei problemi, le città possono diventare motori sostenibili e resilienti, contribuendo a un futuro più equo.
Aproximación a la Geopolítica Orgánica, Cibernética y Cognitiva / An Approach of Organic, Cybernetics and Cognitive Geopolitics
Authors: Herrero Fabregat Clemente 
Published: November 2024

La geopolítica ha estado en relación directa con las estrategias que el poder utiliza para la dominación y control de espacios geográficos. En este proceso se pueden distinguir tres tipos. La orgánica, que partiendo de la concepción del Estado y de la sociedad como un organismo, explica como éste tiende a crecer y a controlar militarmente espacios geográficos. La cibernética que pretende controlar grandes espacios económicos mundiales mediante redes basadas en las nuevas técnicas de información y comunicación. La cognitiva cuyo objetivo es la hegemonía ideológica sobre los grupos sociales. Abstract: Geopolitics has been in direct relation with the strategies that the power uses for the domination and control of geographic spaces. It can be distinguished three types. The organic, starting with the conception of the States and Society like an organism, which explains how it tends to grow and to control militarily and geographically spaces. The cybernetics that pretends to control big world-wide economic spaces by information and communication techniques. The cognitive whose aim is the ideological hegemony on the social groups.
Chronic ischemic gastropathy as an unusual cause of abdominal pain
Authors: Fernández Carrasco M , Plaza Fernández A , Navarro Moreno E , Anguita Montes F , Gálvez Miras A 
Published: November 2024

Abstract

Ischaemic gastropathy is a rare condition with a highly variable clinical spectrum. Its presentation varies from chronic abdominal pain to fatal cases of fulminant gastric ischaemia if it develops abruptly. There are several aetiologies of abdominal pain, however, early diagnosis of this pathology will allow a targeted therapeutic approach, which may improve prognosis and avoid fatal consequences.
Overestimation of Astrophysical Gamma-Ray Energies during Thunderstorms: Synergy of Galactic and Atmospheric Accelerators
Authors: Chilingarian A. , Zazyan M. 
Published: November 2024

Abstract
Particle accelerators abound in space plasmas, saturating the cosmos with fully stripped nuclei and gamma rays, with energies surpassing the capabilities of human-made accelerators by orders of magnitude. Upon reaching Earth’s atmosphere, these particles trigger extensive air showers (EASs), generating millions of secondary cosmic rays of lower energies. Free electrons from EASs developing in the atmosphere are seeds for atmospheric electron accelerators. Strong atmospheric electric fields (AEFs) evolving during thunderstorms act as accelerators, amplifying the intensity of electrons many times, significantly enlarging the EAS size (number of electrons). Thus, the energy of the primary cosmic ray recovered by EAS size can be significantly overestimated. Recently discovered by high-altitude EAS arrays, PeVatron candidates (ultra–high-energy (UHE) astrophysical gamma-ray sources) must be carefully examined according to the atmospheric conditions during EAS detection. Large High Altitude Air Shower Observatory and High-Altitude Water Cherenkov Observatory arrays are located in regions of frequent thunderstorms, and an AEF’s strength can reach and surpass the critical strength to start relativistic runaway electron avalanches. A few registered UHE gamma rays from stellar sources can be registered at just this time when the AEF highly enhances the EAS size. Thunderstorm ground enhancements are copiously registered at mountain peaks of Eastern Europe, Germany, and Armenia, with energies well above the threshold energy of EAS array scintillators. Thus, the overestimation of the energy of primary particles is not an exotic process but a consequence of already well-established physical phenomena. Consequently, a report on each registered UHE gamma ray should include the recorded time and corresponding weather conditions.
The evolutionary history and ecological adaptation of Capulus danieli (Littorinimorpha, Capulidae)
Authors: Xie Yaoyu , Han Yida , Jia Menghao , Cai Linxuan , Zhao Bin , Hao Zhenlin , Tian Ying 
Published: November 2024

Capulus danieli, a distinct member of Capulidae, with a limpet-shaped shell,&nbsp;exhibits a unique ecological behaviour by attaching and drilling onto the shells of scallops, distinguishing itself from other members of the&nbsp;gastropod&nbsp;class,&nbsp;offering a compelling case for evolutionary and ecological study.&nbsp;This study initially obtained the complete mitochondrial genome of C. danieli&nbsp;through second-generation sequencing.&nbsp;In addition, 25&nbsp;species closely related to C. danieli&nbsp;were selected to establish phylogenetic analysis using Maximum Likelihood (ML) and Bayesian Inference (BI) methods.&nbsp;Furthermore,&nbsp;a divergence time tree of Capulidae was constructed based on the analysis of the 16S&nbsp;rRNA gene sequence&nbsp;of 11 Capulidae species.
The results showed that the mitochondrial genome of C.&nbsp;danieli&nbsp;is similar to most known neogastropods, confirming&nbsp;the first record&nbsp;of this species in China.&nbsp;The phylogenetic analysis also revealed a close evolutionary relationship between C. danieli&nbsp;(Family Capulidae) and Ficus subintermedia, Ficus variegata&nbsp;(Family Ficidae)&nbsp;within the Order Littorinimorpha. The divergence time estimation suggested that C.&nbsp;danieli&nbsp;diverged approximately 52.29 million years ago.&nbsp;The genus Capulus of mollusks exhibits morphological plasticity, adapting their form to better suit their parasitic lifestyle. This adaptability may aid in their survival and reproduction on various hosts. The adaptive changes in the shell morphology of Capulus&nbsp;species in response to the&nbsp;morphology&nbsp;of their host shells can be considered an example of co-evolution.
Correlating the genetic alterations and expression profile of the TRA2B gene in HNSCC and LUSC
Authors: Esakki Amba , Pandi Anitha , Girija Smiline A S , Jayaseelan Vijayashree Priyadharsini 
Published: November 2024

Introduction: Transformer (TRA2B) is a serine/arginine-rich (SR)-like protein family that regulates the alternative splicing of several genes in a concentration-dependent manner. Amplification of the TRA2B gene, which codes for TRA2B, occurs in several malignancies, including those of the lung, cervix, head and neck, ovary, stomach, and uterine.
Materials and methods: The present study design follows a computational approach to predict the molecular mechanisms underlying TRA2B alterations in two cancer phenotypes, viz., lung and head and neck squamous cell carcinoma. The genetic alteration in the TRA2B gene was identified using the cBioportal database. The gene expression pattern in both the cancer types and their survival pattern concerning the expression profile was demonstrated using UALCAN. The microRNA targets of the TRA2B gene were identified using the miRDB database.
Results: Genetic alteration was found to be 27% and 48% in HNSCC and LUSC datasets, respectively. The alterations included gene amplification, missense, nonsense, and splice site mutations. The gene expression profile of TRA2B correlated well with the gene amplification demonstrated by patients in both groups. However, the upregulation of TRA2B did not correlate well with the survival profile in LUSC patients. The downregulation of TRA2B markedly affected the survival of HNSCC patients, which can be attributed to the functions of microRNAs targeting TRA2B transcripts.
Conclusion: Although TRA2B was found to be a potential diagnostic marker exhibiting a differential expression pattern for HNSCC, the employability of this gene as a prognostic marker needs more experimentation. Also, the influence of microRNAs on dysregulated gene expression should be considered to gain a better understanding of the underlying molecular mechanisms precipitating the disease.
Attitudes and awareness related to cervical cancer vaccine
Authors: Ruschukova Darina N. , Momchilova Teodora D. , Vladimirova Marieta S. , Nikolova Zlatina I. , Indjian Krikor O. 
Published: November 2024

Introduction: Cervical cancer causes major morbidity and mortality around the world. This makes prophylactic vaccines a significant tool for preventing the disease. As these vaccines become more widely available, they have the potential to drastically lower the cancer’s prevalence and burden in the future.
Aim: The aim of this study was to assess the attitudes toward awareness of the human papillomavirus (HPV) vaccination.
Materials and methods: A pilot, cross-sectional, medicosocial survey was conducted using a structured, anonymous online questionnaire, including self-assessment questions on awareness and attitudes towards HPV vaccination. Sixty-four adult female parents of female children participated in the study between June and August 2023. The design and conduct of the study was done with the personal involvement of the researchers. SPSS v. 23.0 was used to analyze the primary statistical information. The results obtained were presented graphically using MS Excel 2010.
Results: We found significantly good awareness and negative attitude towards vaccination as prevention against HPV.
Conclusion: The present study demonstrated that respondents had a relatively good awareness of cervical cancer, the risk factors associated with the disease, and the virus that causes it. There was a correlation between socio-demographic characteristics and awareness of the study population. The respondents had a certain distrust of the vaccine. The dissatisfaction stemmed from the fact that vaccination was not a substitute for routine cervical screening, was not 100% effective, and did not provide protection against any type of papilloma virus or against pre-existing HPV infections.
The low vaccination coverage in Bulgaria leads the authors to believe that our country urgently needs new strategies and approaches in the fight against cervical cancer, through continuous training of medical personnel, inclusion of immunization programs in school health care, and improved health education and awareness of HPV vaccination among adolescent girls and their parents.
Thoracoabdominal approach to large adrenal tumors – when laparoscopic adrenalectomy is not enough: a retrospective four-year study
Authors: Tsalis Konstantinos , Ioannidis Orestis , Savvala Natalia Antigoni , Gkasdaris Grigorios , Christidis Panagiotis , Anestiadou Elissavet , Mantzoros Ioannis , Pramateftakis Manousos , Kotidis Efstathios , Ouzounidis Nikolaos , Foutsitzis Vasilis , Symeonidis Savvas , Bitsianis Stefanos , Cheva Angeliki , Angelopoulos Stamatios 
Published: November 2024

Introduction: Laparoscopic adrenalectomy is considered to be the gold standard approach in the field of adrenal surgery. This technique offers advantages of great importance compared to variant laparotomy techniques. Notwithstanding, a technique that needs to be mentioned is the thoracoabdominal approach which facilitates the anatomic exposure of the retroperitoneum, adrenal gland, and great vessels and is strongly recommended for the surgery of large, malignant adrenal tumors.
Aim: The objective of this study is to evaluate the effectiveness and outcomes of the thoracoabdominal approach in adrenal surgery for large adrenal tumors. By presenting our results and experiences, we aim to highlight the advantages of this technique in providing optimal anatomic exposure of the retroperitoneum, adrenal gland, and great vessels, and to establish its role as a viable alternative to laparoscopic adrenalectomy in complex cases.
Materials and methods: We reviewed retrospectively the data of our patients admitted to our Surgical Department and treated surgically with the thoracoabdominal incision, performed by a single surgeon at our tertiary care center, over the period 01/01/20-31/12/23.
Results: All patients had large retroperitoneal masses of varying complexity, requiring maximal surgical exposure. Seventeen patients in total underwent operation with the indication of unilateral adrenal tumor. Five of those patients underwent a laparoscopic tumor resection, while 12 patients were treated by thoracoabdominal approach. Our study group included 7 women (58%) and 5 men (42%), with average age 57 years. The mean maximum tumor diameter was 10.8 cm.
Conclusion: The advantages of the thoracoabdominal approach regarding the exposure of the operative field in challenging cases, together with the low incidence of complications noted in our experience, render this technique an excellent alternative if indicated.
Lower cross syndrome: specific treatment protocol versus generalized treatment protocol. A randomized single-blinded trial
Authors: Mehta Trupti B. , Sharma Amit 
Published: November 2024

Introduction: Lower crossed syndrome (LCS) is a biomechanical muscle imbalance causing low back pain.
Aim: This study aimed to compare specific treatment protocols versus generalized treatment protocols for managing low back pain associated with LCS.
Materials and methods: This randomized, single-blinded trial involved 200 patients (aged 20-40 years) with low back pain and LCS. Patients were divided into four groups: A1 and A2 (specific protocols for posterior and anterior LCS), and B1 and B2 (generalized protocols). Interventions were administered thrice weekly for two weeks. Outcome measures included Numerical Pain Rating Scale (NPRS), Modified Oswestry Disability Questionnaire (MODQ), Lumbar Lordosis Index (LLI), abdominal and gluteal muscle strength, and iliopsoas and back extensor flexibility.
Results: All groups showed significant improvements in all parameters (p&lt;0.01). However, specific protocols demonstrated superior outcomes. Group A1 showed the greatest reductions in pain (median NPRS decrease: 5), disability (median MODQ decrease: 45), iliopsoas tightness (median decrease: 12°) and back extensor tightness (median decrease 6.5). Group A2 exhibited the highest improvements in abdominal strength (median increase: 8 kg) and gluteal muscle strength (median increase: 8 kg).
Conclusion: Specific treatment protocols were significantly more effective than generalized protocols in managing low back pain associated with LCS. These findings emphasize the importance of accurate LCS classification and tailored interventions for optimal therapeutic outcomes in patients with low back pain.
Clinical and echocardiographic characteristics of patients with atrial cardiomyopathy and their impact on prognosis
Authors: Ilieva Radostina , Kinova Elena , Slavchev Boris , Kalaydzhiev Petar , Somleva Desislava , Goudev Assen 
Published: November 2024

Introduction: Patients with diverse demographic and clinical characteristics and comorbidities are included in the category of atrial cardiomyopathy (ACM).
Aim: Our study aims to evaluate the demographic, clinical, laboratory, and echocardiographic parameters of patients with ACM and to assess their impact on prognosis.
Materials and methods: Only 200 of the 724 consecutively evaluated patients with dilated left atrium who met the criteria for advanced ACM were included in the analysis. Forty age- and sex-matched controls with normal left atrial volume were also included. On enrollment, all patients received a detailed echocardiography with volumetric and speckle tracking analysis, and they were followed for 36 months for cardiovascular outcomes, including mortality.
Results: The mean age of the ACM population was 73.91±9.74 years, with 58% being women. Hypertension was found in 93% of them, 79% had atrial fibrillation, 60% had heart failure, 37% were obese, and 26% had diabetes. Over a median follow-up of 20.6 months, 35 deaths were registered in the ACM group compared to 1 death in the control group (17.5% vs. 2%, p=0.011). The presence of heart failure (HR 5.2, p=0.004), cancer (HR 3.7, p=0.007), severe tricuspid regurgitation (TR) (HR 5.4, p&lt;0.001), high NT-proBNP (HR 1.4, p&lt;0.001), and low right ventricular free wall strain (RVFWLS) (HR 1.2, p=0.006) were predictors of poor outcome.
Conclusion: In patients with ACM, the most prevalent comorbidities are hypertension, atrial fibrillation, heart failure, obesity, and diabetes. ACM is associated with high mortality with the best echocardiographic predictors – the presence of severe TR and RVFWLS &gt;−17 %.
Gender differences in weight-adjusted waist index in elderly inhabitants of a geriatric center
Authors: Huremović Amila , Dervišević Amela , Lepara Orhan , Valjevac Amina , Začiragić Asija 
Published: November 2024

Introduction and aim: Weight-adjusted waist index (WWI) represents a novel anthropometric measure for assessing obesity. Bearing in mind that there is insufficient data in the literature regarding gender differences in WWI values, the aim of the current study was to examine gender differences in WWI values among older adults.
Materials and methods: The research was conducted at the Sarajevo Gerontological Center, Bosnia and Herzegovina. The study design was cross-sectional. It included 151 participants aged 65 years and older (66 males and 85 females). Anthropometric parameters as well as data on blood pressure were gathered. WWI was calculated by dividing waist circumference (in cm) by the square root of body weight (in kg). Differences between compared groups were analyzed using the Student t-test, Mann-Whitney U or chi-square test. The Spearman’s test was used to assess correlations.
Results: Elderly women had significantly higher values of WWI compared to men. In elderly male participants, there was a statistically significant positive correlation between WWI and waist circumference, hip circumference, neck circumference, and mid-upper arm circumference, but no statistically significant correlation was found with BMI. In elderly female participants, statistically significant positive correlation between WWI and all tested anthropometric measures was found.
Conclusion: The differences in WWI values between genders observed in the present study highlight its gender-specific implications and underline the importance of considering gender when interpreting WWI in clinical and research settings. Further research is warranted to explore additional health implications and validate WWI utility across diverse populations and age groups.