bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nobeyama 45 m Cygnus-X CO Survey. I. Photodissociation of Molecules Revealed by the Unbiased Large-scale CN and C18O Maps
Authors: Yamagishi M. , Nishimura A. , Fujita S. , Takekoshi T. , Matsuo M. , Minamidani T. , Taniguchi K. , Tokuda K. , Shimajiri Y. 
Published: March 2018

Abstract
We present an unbiased large-scale (9 deg2) CN (N = 1–0) and C18O (J = 1–0) survey of Cygnus-X conducted with the Nobeyama 45 m Cygnus-X CO survey. CN and C18O are detected in various objects toward the Cygnus-X North and South (e.g., DR17, DR18, DR21, DR22, DR23, and W75N). We find that CN/C18O integrated intensity ratios are systematically different from region to region, and are especially enhanced in DR17 and DR18, which are irradiated by the nearby OB stars. This result suggests that CN/C18O ratios are enhanced via photodissociation reactions. We investigate the relation between the CN/C18O ratio and strength of the UV radiation field. As a result, we find that CN/C18O ratios correlate with the far-UV intensities, G
0. We also find that CN/C18O ratios decrease inside molecular clouds, where the interstellar UV radiation is reduced due to the interstellar dust extinction. We conclude that the CN/C18O ratio is controlled by the UV radiation, and is a good probe of photon-dominated regions.
One-year Predictors of Presenteeism in Workers with Rheumatoid Arthritis: Disease-related Factors and Characteristics of General Health and Work
Authors: Boot Cécile R.L. , de Wind Astrid , van Vilsteren Myrthe , van der Beek Allard J. , van Schaardenburg Dirkjan , Anema Johannes R. 
Published: March 2018

Objective.Rheumatoid arthritis (RA) affects adults of working age and leads to productivity losses because of presenteeism that results from limitations while at work. The aim of our study was to gain insight into disease-related factors, general health, and work characteristics as predictors of presenteeism in workers with RA.Methods.Workers with RA (n = 150) recruited by rheumatologists completed questionnaires at baseline and after 1 year. Medical information was retrieved from patient records. Presenteeism was measured by the Work Limitations Questionnaire. Disease [28-joint Disease Activity Score (DAS28), Health Assessment Questionnaire (HAQ), pain, fatigue], general health (mental, physical, deterioration of health), and work characteristics (work instability, social support, workload) were assessed as predictors of presenteeism after 1 year using linear regression analyses.Results.Presenteeism was 4.0 h over a 2-week period based on an average work week of 28.7 hours. More RA-related disability (HAQ; B = −1.20, 95% CI −2.12 to −0.28), poorer mental health (B = −0.04, 95% CI −0.08 to −0.01), and health deterioration over a 1-year period (B: −0.02, 95% CI −0.04 to −0.01) were associated with more presenteeism. Work characteristics were not associated with presenteeism.Conclusion.Disease-related factors and general health characteristics were significantly associated with presenteeism at 1-year followup, although the effects of the general health characteristics were considered not to be relevant. To reduce presenteeism and improve functioning at work, it is important to pay attention to reducing RA-related disability in addition to reducing disease activity. A broader perspective is needed and should also take into account the level of RA-related disability.
Vers un enracinement cosmopolite
Authors: Biland Émilie , Desage Fabien 
Published: March 2018

Dans un livre désormais classique, le politiste américain Sydney Tarrow soulignait les ressources internes mobilisées par les militant·e·s engagé·e·s dans des causes transnationales, évoquant des formes de « cosmopolitisme enraciné ». En analysant le développement récent des circulations entre la France et le Québec, cet article montre, de manière symétrique, combien la comparaison internationale constitue une dimension de plus en plus fréquente, voire obligée, de pratiques sociales et politiques ancrées localement et/ou nationalement. Ainsi, et en dépit des multiples différences qui caractérisent ces sociétés si souvent rapprochées, la France et le Québec tendent à former un vis-à-vis comparatif , dont les ressortissant·e·s, chercheur·e·s mais aussi et surtout fonctionnaires, militant·e·s, élu·e·s, journalistes – tendent à se comparer. Défendant une épistémologie réflexive, cet article invite donc les comparatistes savants à interroger leurs propres méthodes, en tenant compte des usages ordinaires de la comparaison parmi leurs enquêté·e·s (qui se comparent, autant qu’on les compare), ainsi que des enjeux internes de ce comparatisme désormais généralisé.
« Au nom du peuple » ? Circulations du « populisme » et représentations du populaire au Québec
Authors: Mazot-Oudin Antoine 
Published: March 2018

Les usages savants et médiatiques de la notion de « populisme » apparaissent au début des années 2000 au Québec, deux décennies plus tard qu’en France. Les auteurs qui utilisent cette notion pour analyser la scène électorale québécoise naviguent entre des références tantôt françaises, tantôt nord-américaines, mais décrivent un « peuple » aux propriétés sociales bien distinctes des groupes sociaux visés par ce terme en France. Comprendre les dynamiques de circulation, de traduction et de réception de la notion de « populisme » au Québec nécessite de se pencher simultanément sur les trajectoires des intellectuels impliqués dans ces processus et sur les spécificités de ce contexte d’énonciation. La moindre importance de la sociologie politique des groupes sociaux au Québec influence notamment les manières de (se) représenter le populaire à l’aide de cette catégorie.
Free jazz made in France. Contribution à l’étude des dynamiques de radicalisation dans la France des années 1960 et 1970
Authors: Voilliot Christophe 
Published: March 2018

Cet article est une contribution à l’analyse des phénomènes de surenchère à la radicalité à partir de l’étude des musiciens qui se sont réclamés de l’esthétique du free jazz en France. Si l’assignation à la radicalité de ce courant musical est d’abord le fruit d’un transfert et d’une réception complexe et décalée d’une forme musicale apparue aux États-Unis par ses commentateurs français, elle fait aussi écho à l’engagement politique de musiciens dans le contexte du « mai » français et du désengagement lié au reflux militant des années 1970. En les restituant, à partir de témoignages et de l’étude de la presse musicale et militante de l’époque, cet article tente de reconstruire une dynamique de radicalisation à la fois originale et partiellement oblitérée.
Preceptor Education for Specialty Community-Based Nurses: A Pre- and Postevaluation
Authors: Mitchell Creina , Ridgway Lael , Sheeran Leanne 
Published: March 2018

Background:Quality preceptorship is an integral aspect of nursing education. Evidence suggests that preceptor education programs can be designed to support RNs in their capacity as preceptors. Little has been reported on the effectiveness of preceptor programs for community-based nurses who provide primary health care for preschool children and their families.Method:The project evaluated the effectiveness of a 4-hour face-to-face tailored preceptor education program undertaken by 59 nurses in Victoria, Australia. Pre- and postsurveys were undertaken to evaluate the program.Results:Participants had improved understanding of the role of preceptor after the education program. They had increased confidence in their ability to give feedback, assess clinical skills, and use the clinical assessment tool. They were also surer of the standard of performance expected of students.Conclusion:A strategically designed preceptor program was effective in improving some preceptorship skills of community-based nurses who supervise postgraduate nursing students.J Contin Educ Nurs.2018;49(3):111–118.
Journal Clubs: Engaging Clinical Nurses and Midwives in Research
Authors: Cooper Alannah L. , Brown Janie A. 
Published: March 2018

It is essential that nurses and midwives can understand and critically evaluate research to ensure the delivery of high-quality evidence-based care. Journal clubs are an educational method that helps to develop research capacity and assist with bridging the gap between research and clinical practice. To maintain competence and remain current with the latest evidence, a commitment to continuing professional education is required. This article describes how a successful journal club led to clinical nurses identifying a gap in their own practice, which resulted in a research project being conducted by the members of the journal club.J Contin Educ Nurs.2018;49(3):141–144.
Feasibility and Pilot Testing of a Mindfulness Intervention for Frail Older Adults and Individuals With Dementia
Authors: Kovach Christine R. , Evans Crystal-Rae , Sattell Lisa , Rosenau Kimberly , Gopalakrishnan Sandeep 
Published: March 2018

Mindfulness interventions have been beneficial for healthy adults and individuals experiencing a stressful medical or mental health diagnosis. The purposes of the current study were to: (a) determine feasibility of mindfulness for older adults in long-term residential settings, and (b) examine differences in outcomes between a mindfulness and cognitive activity. The current study is the first mindfulness study to include individuals in moderate and severe stages of dementia, and included 36 individuals with a range of cognitive abilities. A crossover design was used, and the intervention was feasible for continued practice by individuals with cognitive impairment. Statistically significant short-term changes in agitation, discomfort, anger, and anxiety were found. Nighttime sleep did not improve, but participants slept less during the day. Long-term changes in outcomes were not found. Mindfulness may be useful in decreasing emotional reactivity and improving well-being of older adults in long-term care.

Targets:
Individuals with multiple chronic conditions, including cognitive impairment.

Intervention Description:
The Present in the Now (PIN) intervention is a mindfulness intervention with three components: attentional skill exercises, body awareness activities, and compassion meditation.

Mechanisms of Action:
Mindfulness acts to decrease emotional reactivity through cognitive and affective mechanisms of action and neural activation of the cingulate cortex, amygdala, and hippocampus.

Outcomes:
Agitation, affect, stress, sleep, discomfort, and communication of need.

[Res Gerontol Nurs. 2018; 11(3):137–150.]
Supporting Transitions in Care for Older Adults With Type 2 Diabetes Mellitus and Obesity
Authors: Whitehouse Christina R. , Sharts-Hopko Nancy C. , Smeltzer Suzanne C. , Horowitz David A. 
Published: March 2018

The aim of the current study was to compare outcomes for older adults with type 2 diabetes mellitus and obesity following participation in a transitional care intervention that included diabetes self-management education (DSME) and homecare. The three groups analyzed comprised an inpatient DSME plus homecare group (
n
= 35); an inpatient DSME only group (
n
= 100); and a group who received usual care (
n
= 45). Outcomes of interest included rehospitalization rates and hemoglobin A1C (A1C) for up to 1-year post hospital discharge. Rates of rehospitalization and A1C improved for older adults who received nurse-led inpatient DSME and homecare during transitions of care from hospital to home. Rehospitalization rates up to 90 days were decreased for the DSME plus homecare group (10%) compared to DSME only (20%) and usual care groups (26.7%) (
p
< 0.05). A decrease of −0.4 and −2.3 A1C units was observed for the DSME group and DSME plus homecare group, respectively, at 90 days. These results support a transitional care educational intervention for older adults with type 2 diabetes mellitus and obesity.

Targets:
Older adults with type 2 diabetes mellitus and obesity.

Intervention Description:
Transitional care intervention including diabetes self-management education and homecare.

Mechanisms of Action:
Inpatient diabetes education and homecare helps improve rates of rehospitalization and hemoglobin A1C during care transitions from hospital to home.

Outcomes:
Rehospitalization rates, glycemic control (i.e., A1C level).

[Res Gerontol Nurs. 2018; 11(2):71–81.]
TEACHING VISUAL SCRIPTING IN BIM: A CASE STUDY USING A PANEL CONTROLLED BY SOLAR ANGLES
Authors: Kensek Karen M. 
Published: March 2018

Programming and scripting can be used to activate a 3D parametric model to create a more intelligent and flexible building information model. There has been a trend in the building industry towards the use of visual scripting that allow users to create customized, flexible, and powerful programs without having to first learn how to write traditional code. Using visual scripting, users graphically interact with program elements instead of typing lines of text-based code. Nodes are created and virtually wired together; they can be numbers, sliders for adjusting values, operators and functions, list manipulation tools, graphic creators, and other types. Text based coding programs such as Python can also be used for the creation of custom nodes when greater flexibility is desired. Examples from professional firms include scripts that help automate work in the office to increase efficiency and accuracy (e.g. create escape routes, renumber rooms by levels, create documentation), assist in form generation (e.g. parametric design of metal panels, rebar generation, coordination between Revit and Rhino), analyze BIM files (e.g. terminal airflow, visual loads and capacity), and provide analysis results (e.g. daylighting, thermal comfort, window optimization). One can learn the basic steps of learning a visual programming language through the use of Dynamo within Autodesk Revit. The example used is for a façade component that changes based on the sun's altitude.
A SURVEY OF SOLAR ENVELOPE PROPERTIES USING SOLID MODELLING
Authors: Stasinopoulos Thanos N. 
Published: March 2018

Solar envelope is a concept for regulating solar access in urban planning. It is a roof-like imaginary surface over a given piece of land that controls the maximum allowed building height in order to avoid casting shadows on the neighbours during a specific period. The volume of solar envelopes regulates building density, depending on geometric attributes and time (plot size and proportions, orientation, ground slope, latitude, duration of insolation). This work compares the effect of such factors on the size of solar envelopes on a variety of land parcels, individually or in groups. Repeated applications of solid modelling are used to calculate in each case the values of ‘Solar Volume Coefficient’, i.e. the volume of a solar envelope per unit of its base as a measure for comparisons. Results show the influence of the various factors affecting the geometry of solar envelopes. Among other findings, it is also shown that solar envelopes generate urban densities lower than conventional urban regulations. The total volume of solar envelopes over an area ( ‘Solar Building Potential’) can be increased by raising the reference level of solar envelopes ( ‘shadow fence’ or ‘solar fence’). Lower urban densities are compensated by facilitating solar applications, as well as by enhancing daylight, ventilation, and vistas in the urban context, thus creating new ‘solar cityscapes’ exemplified here on existing street patterns.
Subprimes, signaux faibles et véridiction
Authors: de Oliveira-Verger Christelle 
Published: March 2018

La crise des subprimes débute en 2007 aux États-Unis par une crise immobilière liée aux très nombreux impayés des prêts subprimes. L’auteure étudie un événement marquant de ce début de crise, se déroulant dans un contexte économique « normal » : la mise en difficulté de la BNP par les crédits subprimes et son traitement dans la presse. Cela pour comprendre, au travers de la problématique de la véridiction, la volonté de non prise en compte de certains signaux annonciateurs de cette crise et leur impact réel sur le devenir du système, contribuant alors à provoquer une crise financière mondiale.
Penser politiquement la communication publique
Authors: Demers François , Rueff Julien 
Published: March 2018

Le syntagme « communication publique » désigne un domaine d’études s’intéressant aux manifestations multiples et variables de la parole publique. Le présent article examine plusieurs présupposés partagés par les recherches en communication publique, dans l’idée d’évaluer leur adéquation avec l’intention de donner une intelligibilité politique à ces phénomènes communicationnels. À la lumière de la pensée politique d’Antonio Gramsci, les auteurs analysent dans quelle mesure ces présupposés permettent de penser la compénétration des modalités coercitive et discursive du pouvoir politique, les antagonismes irréductibles et indécidables entre les groupes sociaux, mais aussi les articulations entre la société civile et la société politique.
De l’utilisation de Facebook à des fins de mobilisation par le groupe Sauvons Calais
Authors: Gardenier Matthijs , Monie Aymeric 
Published: March 2018

Le présent article est issu d’un projet de recherche sur le vigilantisme consacré à Sauvons Calais, groupe d’extrême droite qui entend lutter contre l’immigration « sauvage ». Il se focalise sur l’usage, par ce collectif militant, d’internet, plus particulièrement de Facebook, pour diffuser ses positions politiques, mais aussi pour mobiliser les citoyens par des appels à l’action collective et au vigilantisme.
Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity
Authors: Dixon Karen O. , Schorer Michelle , Nevin James , Etminan Yassaman , Amoozgar Zohreh , Kondo Takaaki , Kurtulus Sema , Kassam Nasim , Sobel Raymond A. , Fukumura Dai , Jain Rakesh K. , Anderson Ana C. , Kuchroo Vijay K. , Joller Nicole 
Published: March 2018

Abstract
Coinhibitory receptors, such as CTLA-4 and PD-1, play a critical role in maintaining immune homeostasis by dampening T cell responses. Recently, they have gained attention as therapeutic targets in chronic disease settings where their dysregulated expression contributes to suppressed immune responses. The novel coinhibitory receptor TIGIT (T cell Ig and ITIM domain) has been shown to play an important role in modulating immune responses in the context of autoimmunity and cancer. However, the molecular mechanisms by which TIGIT modulates immune responses are still insufficiently understood. We have generated a panel of monoclonal anti-mouse TIGIT Abs that show functional properties in mice in vivo and can serve as important tools to study the underlying mechanisms of TIGIT function. We have identified agonistic as well as blocking anti-TIGIT Ab clones that are capable of modulating T cell responses in vivo. Administration of either agonist or blocking anti-TIGIT Abs modulated autoimmune disease severity whereas administration of blocking anti-TIGIT Abs synergized with anti–PD-1 Abs to affect partial or even complete tumor regression. The Abs presented in this study can thus serve as important tools for detailed analysis of TIGIT function in different disease settings and the knowledge gained will provide valuable insight for the development of novel therapeutic approaches targeting TIGIT.
Murine γ-Herpesvirus 68 Induces Severe Lung Inflammation in IL-27–Deficient Mice with Liver Dysfunction Preventable by Oral Neomycin
Authors: Kanai Kyosuke , Park Ah-Mee , Watanabe Akiko , Arikawa Tomohiro , Yasui Teruhito , Yoshida Hiroki , Tsunoda Ikuo , Yoshie Osamu 
Published: March 2018

Abstract
IL-27 is an immunoregulatory cytokine consisting of p28 and EBI3. Its receptor also has two subunits, WSX1 and gp130. Although IL-27 promotes Th1 differentiation in naive T cells, it also induces IL-10 expression in effector Th1 cells to curtail excessive immune responses. By using p28-deficient mice and WSX1-deficient mice (collectively called IL-27–deficient mice), we examined the role of IL-27 in primary infection by murine γ-herpesvirus 68 (MHV68), a murine model of EBV. Upon airway infection with MHV68, IL-27–deficient mice had more aggravated lung inflammation than wild-type mice, although MHV68 infection per se was better controlled in IL-27–deficient mice. Although epithelial cells and alveolar macrophages were primarily infected by MHV68, interstitial macrophages and dendritic cells were the major producers of IL-27. The lung inflammation of IL-27–deficient mice was characterized by more IFN-γ–producing CD8+ T cells and fewer IL-10–producing CD8+ T cells than that of wild-type mice. An infectious mononucleosis–like disease was also aggravated in IL-27–deficient mice, with prominent splenomegaly and severe hepatitis. Infiltration of IFN-γ–producing effector cells and upregulation of the CXCR3 ligand chemokines CXCL9, CXCL10, and CXCL11 were noted in the liver of MHV68-infected mice. Oral neomycin effectively ameliorated hepatitis, with decreased production of these chemokines in the liver, suggesting that the intestinal microbiota plays a role in liver inflammation through upregulation of these chemokines. Collectively, IL-27 is essential for the generation of IL-10–producing effector cells in primary infection by MHV68. Our findings may also provide new insight into the mechanism of hepatitis associated with infectious mononucleosis.
PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN–Inducible Proteins
Authors: Caprara Greta , Prosperini Elena , Piccolo Viviana , Sigismondo Gianluca , Melacarne Alessia , Cuomo Alessandro , Boothby Mark , Rescigno Maria , Bonaldi Tiziana , Natoli Gioacchino 
Published: March 2018

Abstract
The enzymes of the poly-ADP-ribose polymerase (PARP) superfamily control many relevant cellular processes, but a precise understanding of their activities in different physiological or disease contexts is largely incomplete. We found that transcription of several Parp genes was dynamically regulated upon murine macrophage activation by endotoxin. PARP14 was strongly induced by several inflammatory stimuli and translocated into the nucleus of stimulated cells. Quantitative mass spectrometry analysis showed that PARP14 bound to a group of IFN-stimulated gene (ISG)–encoded proteins, most with an unknown function, and it was required for their nuclear accumulation. Moreover, PARP14 depletion attenuated transcription of primary antiviral response genes regulated by the IFN regulatory transcription factor 3, including Ifnb1, thus reducing IFN-β production and activation of ISGs involved in the secondary antiviral response. In agreement with the above-mentioned data, PARP14 hindered Salmonella typhimurium proliferation in murine macrophages. Overall, these data hint at a role of PARP14 in the control of antimicrobial responses and specifically in nuclear activities of a subgroup of ISG-encoded proteins.