bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antioxidant Potential of Ethanol and Ethyl Acetat Extract of Ganoderma sp. Mycelium
Authors: Ratnaningtyas Nuniek Ina , Purnomowati Purnomowati , Purwati Endang Sri , Septiana Aisyah Tri , Ekowati Nuraeni , Supriyadi Adi 
Published: May 2018

Ganoderma sp. Banyumas 1 isolate that reffered as Ganoderma sp. is a new discovered isolate from Banyumas, Central Java, Indonesia expected to have a potential properties of antioxidant of medicinal mushroom. This study aimed to determine the antioxidant potential and the appropriate solvent for it’s extracting from Ganoderma sp. This research result showed that ethyl acetate was able to extract as many as 15.57%, while etanol was only able to extract 3.87% active compounds from dried 28 days old Ganoderma sp. mycelium cultivated in the Mushroom Complete Medium (MCM). Extract of ethyl acetate (non-polar) extraction of mycelium of Ganoderma sp. had a potential character as an antioxidant source and performed a better result than from ethanolic (polar) extraction as shown in the IC50 value. Extract from ethyl acetate extraction had an average IC50 value smaller than from ethanolic extract (581.80 < 1285.67). Extract from ethyl acetate extraction resulted in a higher amount of phenol than that ethanolic extract 29.23 < 57.67. Inhibition percentage of both extracts at 65% was known to occur at concentration of 1000 ppm for ethyl acetate extract and 2000 ppm for ethanolic extract. An important finding was that ethyl acetate can be used as appropriate solvent for extracting antioxidant compound better than ethanolic. In conclusion, the mycelium extract of Ganoderma sp. extracted with ethyl acetate and ethanol as solvent is potential to be used as a source of natural antioxidants. This research result has benefit in developing potency of local resources as herbal resources.
Mahameru Soybean (Glycine max) Cultivar, High Salinity Tolerant
Authors: Juwarno Juwarno , Suparjana Tata Brata , Abbas Muachiroh 
Published: May 2018

Mahameru cultivar is high salinity tolerant cultivar. The previous study result showed Mahameru cultivar could tolerate 140mM NaCl, but Cilacap Coast salinity levels often reaching 200mM NaCl. A research of salinity stress on Mahameru cultivar at 200 mM NaCl have not conducted yet. Therefore to conduct the research of Mahameru at high salinity stress to obtained high salinity tolerant soybean cultivar. The observed variables are anatomy (epidermis thickness, the density of stomata and trichomes, palisade thickness) physiology (the dry weight of roots and canopy, the content of chlorophyll a and b) Production (whole pod, total filled pod, total empty pod, weight per one-hundred beans). The salinity treatment was 0, 50,100, 150, 200 mM NaCl given at three days before planting and twenty-one days after planting. The data of anatomy and physiology was taken at forty-five days after planting. The production data was taken when soybean plants turned brown. The result indicates that salinity affects anatomy characteristic of leaf, higher the salinity increasing epidermis thickness and the density of stomata and trichomes. Salinity affected the content of chlorophyll a and b. Higher the salinity increased the content of chlorophyll a and b. Salinity did not affect soybean production. Based on this study Mahameru cultivar is resistant to salinity up to 200 mM NaCl. The benefit of this research help to enhance national soybean production with utilization coastal land for soybean planting Mahameru cultivar.
Antioxidant Effect of Clorella vulgaris on Wistar Rat Kidney Induced by CCl4: A Histopathological Review
Authors: Susatyo Priyo , Rifanda Achmad Akbar , Simanjuntak Sorta Basar Ida , Chasanah Titi 
Published: May 2018

Kidney is very susceptible to damage by toxicological compounds such as carbon tetrachloride (CCl­4). CCl4 produce free radicals, which cause lipid peroxidation and kidney damage and free radical release, which can be prevented by the administration of exogenous antioxidants, such as Chlorella vulgaris.The aim of study was to determine an effect of antioxidant of C. vulgaris on the histopathological features of Wistar rat kidney which is induced by CCl4. Experimental study with completely randomized design. The variable was histopathology features of the kidneys. The doses of C. vulgaris extract were 3 mg, 4 mg, and 5 mg per 100 grams of rat body weight (BW). The administration of C. vulgaris extract was performed within 30 days, while the CCl4 induction (0.25 ml / 100 g BW) was administered orally on the day 9, 12, 16, 19, 23, and 26. Parameters were histopathology features of renal damage, proportion of tubular cell damage, and Bowman's space diameter. The results showed the administration of C. vulgaris extract was able to reduce the impact of damage caused by CCl4 (p<0.05). This was supported by histologic observations, which was showing a decrease of picnotic and vacuolated cells, normal brush border, and decrease of Bowman's space. In conclusion, 5 mg / 100 g BW of C. vulgaris extract can effectively protect the kidney from damage caused by CCl4. The results of this study strongly support further research on immunostimulant content test C. vulgaris and determine the efficient dose for representative animals mammals also in humans.
Uso sustentable de agostaderos y el sistema vaca-cría en el Noroeste de México
Authors: Alcalá Galván Carlos Hugo , Barraza Guardado Ramón Héctor , Ayala Álvarez Félix , Rueda Puente Edgar Omar 
Published: May 2018

Livestock is an economic activity, dedicated to the breeding of animal species to take advantage of them and of its derivative products, as well as of livestock exploitation itself. However, when relating it to the sustainable use of natural resources in Northwest Mexico, there can be seen some situations that need to be addressed. The present study aims to analyze the production and conservation status of natural resources of beef cattle activity in the cow-calf system in Sonora, Mexico. The diagnosis was based on aspects of regionalization of livestock, the specific characteristics and issues of the systems, and the productive status of rangelands. The results showed that, despite the existence of signs of wildlife utilization and the importance of protecting the habitat status for livestock development in the state of Sonora, Mexico, it is important to implement a series of actions in order to increase the sustainable productivity of soil, soil water resources, the recovery of vegetation cover, improvement of livestock management practices, needs of research and technology transfer, as well as institutional linkage and training of professional human resources.
Respuesta foliar y radical del maíz a la fertilización biológica-química en un suelo Luvisol
Authors: Montejo Martínez David , Casanova Lugo Fernando , García Gómez Martín , Oros Ortega Iván , Díaz Echeverría Víctor , Morales Maldonado Emilio Raymundo 
Published: May 2018

An alternative to replace the excessive use of chemical fertilizers is the use of soil microorganisms. In this regard, using nitrogen fixingbacteria (N) and mycorrhizal fungi may improve the growth of different crops. The objective was to evaluate the influence of Rhizophagus intraradices and Azospirillum brasilense, as well as the addition of chemical fertilizers on foliar and root response of maize crop in Luvisol soil. The study was conducted from October 2014 to January 2015 at the Technological Institute of the Mayan Zone, Quintana Roo, Mexico.A cornculture was established by a randomized complete block design, and four treatments with four replicates: Mycorrhiza and Azospirillum (MA), Mycorrhiza and Azospirillum + 50% chemical fertilizer, (MA + FQ50%), 100% chemical fertilizer FQ100%) in doses of 142-70-00 kg / ha and a control. Stem height and diameter of the plants were measured. In addition, the number and length of roots were monitored by means of the minirhizotron technique at five depths and at different ages of the plants. At the end of the experimental period, leaf and root biomass were quantified. Treatments of FQ100% and MA + FQ50% presented higher total height and higher stem diameter of the plants. Also, these showed the highest number and length of fine roots, compared to the other treatments. However, treatment with MA + FQ50% kept the highest amount of biomass at the end of the crop.
Áreas potenciales para el cultivo de girasol en condiciones de temporal en Guanajuato, México
Authors: López-Rocha Enrique , Mireles-Arriga Ana Isabel , Hernández-Ruíz Jesús , Ruiz-Nieto Jorge Eric , Rucoba-Garcia Armado 
Published: May 2018

In Mexico, in the last five years, there was a 189.50 to 13 219.84 hectares increase in sunflower crop surface under rainfed conditions. Particularly, in 2016, in the state of Guanajuato, approximately 450 hectares were planted. Cultivation under rainfed conditions requires planning including bioclimatic variables to reach the optimal crop yield and development. This work aims to identify bioclimatic potential areas for sunflower cultivation under rainfed conditions in Guanajuato. In autumn-winter 2016, 45 sunflower fields (distributed in eleven towns) were monitored and stratified. Crop yield associated with maximum and minimum temperature, relative humidity, solar radiation, precipitation, and evapotranspiration were recorded. The data from fields with a higher yield than 1.89 t/ha were used to generate polygons with a saturation of 56 abundance points, to calculate the potential distribution using the Maxent software, with 23 bioclimatic variables as predictors. The variables with the highest contribution percentage to the potential distribution were: average temperature of the driest quarter, altitude, moisture regime, and edaphic profile. The potential areas for sunflower cultivation had a surface of 317 028 hectares where the predominant climate is sub-humid warm, the annual mean temperature is 20 °C, the annual mean rainfall is 600 to 800 mm, and the altitude ranges from 500 to 1500 masl.
Over Torsiyonu ve Cerrahi Tedavisi: Tersiyer bir merkezin 5 yıllık deneyimi
Authors: GÜNAY Taner , YARDIMCI Oğuz Devrim , HOCAOĞLU Meryem , DEMİRÇİVİ BÖR Ergül , ERDEM Gamze 
Published: May 2018

Amaç:
Çalışmamızda son 5 yılda hastanemizde over torsiyonu tanısı ile opere ettiğimiz
hastaların klinik ve laboratuvar bulguları ile uygulanan cerrahi tedavi
yöntemlerinin incelenmesi amaçlanmıştır.

Gereç ve Yöntemler: Elektronik
ortamda arşiv taraması yapılarak Ocak 2013 ile Ocak 2018 tarihleri arasında
hastanemizin acil servis servisine başvuran ve over torsiyonu tanısı ile opere
edilen hastaların demografik özelliklerinin yanı sıra klinik ve laboratuvar
bulguları ile uygulanan cerrahi tedavi yaklaşımları kaydedildi ve bulguların
analizi yapıldı.

Bulgular: Kayıtlarına
ulaşılan toplam 32 hastanın yaş ortalaması 27.2±10.5 olarak
bulundu ve 9(%28.1) hasta virgo idi. Acil servise başvuran bütün hastalarda
abdominal ve/veya pelvik ağrı mevcut olup, 15(%46.8) hastada bulantı, 7(%21.8)
hastada kusma ve 2(%6.2) hastada ateş görüldü. Over torsiyonu saptanan 2
hastada gebelik mevcuttu. Olguların 19(%59.3)’unda torsiyon sağ tarafta iken
13(%40.7) olguda sol taraftaydı. Torsiyone olan kitlenin boyutu ortalama 92.5±46.3
mm olup olguların 15(%46.8)’inde ultrasonografik incelemede ovaryen akım
saptanmadı. Hastaların 23(%71.9)’ünde laparoskopik yaklaşım uygulanırken
9(%28.1) hastada laparatomi tercih edildi.

Sonuç: Over torsiyonu jinekolojik acil bir durum olup hastanın
fizik muayene bulguları başta olmak üzere laboratuvar ve görüntüleme sonuçları ile değerlendirilerek erken müdahalesi torsiyone olmuş organların korunabilmesi ve
fonksiyonlarını devam ettirebilmesi için kritik önemdedir. Cerrahi yaklaşımda
da laparoskopi ön planda tercih edilmeli ve organ koruyucu yaklaşımlar tedavide
ilk seçenek olmalıdır.
THE EFFECTS OF FAST DECLINE IN CRUDE OIL PRICES ON THE TANKER MARKET IN THE SHORT RUN
Authors: AÇIK Abdullah , BAŞER Sadık Özlen 
Published: May 2018

Oil prices have been steadily declining to
around $27 since early 2016, while it was at around $120 in early 2013. This
decline will surely have an effect on countries' petroleum demands. Oil
transport by sea, one of the most important instruments of international oil
trade, has also been directly influenced by these developments. The supply
curve is inelastic in the short term and sudden demand increase in the tanker
market has also caused sudden rise in freight rates. Since the entrance of the
new transport capacity into the market lasted for approximately 3 years, this
study examines a period of about 3 years and tries to examine the effects of
oil prices on the tanker market in the short run. The purpose of this study is
to contribute to the existing theory by examining the effects of this
extraordinary decline in the recent era. In this study, the tanker market is
divided into freight, new construction, second hand and scrap market, and each
sub-market is examined separately. Correlation analysis has been used as the
method of study. According to the findings, freight market and second hand
market have been affected positively by the decrease of oil prices. However,
the impact of the fall in oil prices on the new construction market has not
been at the expected level. When the effects on the scrap market were examined,
a relationship has been found in the positive direction as the opposite of the
theory and the hypothesis.
ANALYSING THE TRADE BETWEEN TURKEY AND THE AEGEAN ISLANDS: THE HIDDEN OPPORTUNITIES
Authors: AKDAŞ Onur , AYAZ İlke Sezin , ÖZER ÇAYLAN Didem 
Published: May 2018

Aegean
Islands and Turkey have strict historical and geographical ties. These ties
make social, cultural and commercial interaction inevitable. The trade between
Aegean Islands and Turkey has great potential. Despite high demands from the
Aegean Islands, according to the relevant statistics no sufficient trade
interaction has been established.&nbsp; The
aim of this paper is to analyze the trade potential and reveal the barriers of
trade between Aegean Islands and Turkey. To reach this aim, trade statistics
have been compiled from various sources and interviews have been carried out
with the relevant professionals. The findings supported by the related
literature indicate that as trade barriers range from infrastructural and
procedural process at port and port-centric areas, and underdevelopment of
small-sized ports, to lack of a collaborative culture among the various service
providers involved in the trade and transportation interactions. The solutions
proposed for the related problems are listed in the recommendation section of
this study.Aegean
Islands and Turkey have strict historical and geographical ties. These ties
make social, cultural and commercial interaction inevitable. The trade between
Aegean Islands and Turkey has great potential. Despite high demands from the
Aegean Islands, according to the relevant statistics no sufficient trade
interaction has been established.&nbsp; The
aim of this paper is to analyze the trade potential and reveal the barriers of
trade between Aegean Islands and Turkey. To reach this aim, trade statistics
have been compiled from various sources and interviews have been carried out
with the relevant professionals. The findings supported by the related
literature indicate that as trade barriers range from infrastructural and
procedural process at port and port-centric areas, and underdevelopment of
small-sized ports, to lack of a collaborative culture among the various service
providers involved in the trade and transportation interactions. The solutions
proposed for the related problems are listed in the recommendation section of
this study.
Pyrano[3,2-c]quinoline Derivatives as New Class of α-glucosidase Inhibitors to Treat Type 2 Diabetes: Synthesis, in vitro Biological Evaluation and Kinetic Study
Authors: Heydari Zahra , Mohammadi-Khanaposhtani Maryam , Imanparast Somaye , Faramarzi Mohammad A. , Mahdavi Mohammad , Ranjbar Parviz R. , Larijani Bagher 
Published: May 2018

Background:
Pyrano[3,2-c]quinoline derivatives 6a–n were synthesized via simple
two-step reactions and evaluated for their in vitro α-glucosidase inhibitory activity.
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Methods: Pyrano[3,2-c]quinoline derivatives 6a–n derivatives were prepared from a two-step reaction:
cycloaddition reaction between 1-naphthyl amine 1 and malonic acid 2 to obtain
benzo[h]quinoline-2(1H)-one 3 and reaction of 3 with aryl aldehydes 4 and Meldrum’s acid 5. The
anti- α-glucosidase activity and kinetic study of the synthesized compounds were evaluated using
α-glucosidase from Saccharomyces cerevisiae and p-nitrophenyl-a-D-glucopyranoside as substrate.
The α-glucosidase inhibitory activity of acarbose was evaluated as positive control.

Results:
All of the synthesized compounds, except compounds 6i and 6n, showed more inhibitory
activity than the standard drug acarbose and were also found to be non-cytotoxic. Among the synthesized
compounds, 1-(2-bromophenyl)-1H-benzo[h]pyrano[3,2-c]quinoline-3,12(2H,11H)-dione
6e displayed the highest α-glucosidase inhibitory activity (IC50 = 63.7 ± 0.5 µM). Kinetic study of
enzyme inhibition indicated that the most potent compound, 6e, is a non-competitive inhibitor of
α-glucosidase with a Ki value of 72 µM. Additionally, based on the Lipinski rule of 5, the
synthesized compounds were found to be potential orally active drugs.

Conclusion:
Our results suggest that the synthesized compounds are promising candidates for
treating type 2 diabetes.
Using Smartphone Apps to Promote Psychiatric Rehabilitation in a Peer-Led Community Support Program: Pilot Study
Authors: Mueller Nora E , Panch Trishan , Macias Cathaleene , Cohen Bruce M , Ongur Dost , Baker Justin T 
Published: May 2018

Background
Management of severe and persistent mental illness is a complex, resource-intensive challenge for individuals, their families, treaters, and the health care system at large. Community-based rehabilitation, in which peer specialists provide support for individuals managing their own condition, has demonstrated effectiveness but has only been implemented in specialty centers. It remains unclear how the peer-based community rehabilitation model could be expanded, given that it requires significant resources to both establish and maintain.

Objective
Here, we describe the results from a study of one such program implemented within Waverley Place, a community support program at McLean Hospital, emphasizing psychiatric rehabilitation for individuals with severe and persistent mental illness, as well as describing the challenges encountered during the implementation of the program. Key questions were whether the patients could, and would, successfully use the app.

Methods
The smartphone app offered multiple features relevant to psychiatric rehabilitation, including daily task lists, activity tracking, and text messaging with peer specialists. A 90-day program of activities, goals, and content specific to the community support program was created on the basis of a prior pilot, in collaboration between members of the app development team (WellFrame), and peers, clinical, and research staff associated with the program. Hospital research staff recruited patients into the study, monitored peer and patient engagement, and handled all raw data acquired from the study.

Results
Of 100 people approached for the study, a total of 13 provided consent, of which 10 downloaded and used the app. Two patients were unable to complete the app installation. Five used the app regularly as part of their daily lives for at least 20 days of the 90-day program. We were unable to identify any specific factors (eg, clinical or demographic) that affected willingness to consent or engage with the app platform in the very limited sample, although the individuals with significant app use were generally satisfied with the experience.

Conclusions
Smartphone apps may become a useful tool for psychiatric rehabilitation, addressing both psychiatric and co-occurring medical problems. Individualizing functions to each patient and facilitating connection with a certified peer specialist may be an important feature of useful apps. Unlike prior reports emphasizing that patients with schizophrenia will adopt smartphone platforms, we found that implementation of digital tools into existing community support programs for severe and persistent mental illness has many challenges yet to be fully overcome to realize the potential benefits such apps could have to promote systematization and cost reduction for psychiatric rehabilitation.
Involuntary Attention Restoration During Exposure to Mobile-Based 360° Virtual Nature in Healthy Adults With Different Levels of Restorative Experience: Event-Related Potential Study (Preprint)
Authors: Chung Kyungmi , Lee Daeho , Park Jin Young 
Published: May 2018

BACKGROUND

With the global trend of urbanization, there are increasing reports of a possible association between decreased exposure to nature and increased occurrence of mental disorders. New 360° virtual reality (VR) technology using smartphones and portable VR glasses can overcome spatial and temporal limitations to help people deal with mental fatigue in everyday life.

OBJECTIVE

On the basis of attention restoration theory (ART), this study aimed to investigate whether the amplitude of the mismatch negativity (MMN)/P3a complex could act as an event-related potential (ERP) biomarker of involuntary attention restoration during exposure to 360° virtual nature in healthy young adults with different levels of restorative VR experience.

METHODS

A total of 40 healthy adults completed prequestionnaires on demographics and simulator sickness and postquestionnaires on simulator sickness and perceived restorativeness before and after exposure to virtual nature, respectively. During the VR exposure, brain activity was measured by electroencephalography as participants were asked to conduct a 2-tone passive auditory oddball task.

RESULTS

The amplitude and latency of the MMN/P3a complex were compared between individuals reporting a highly restorative experience and those reporting a less restorative experience. Although viewing a virtual nature environment, the high restorative group (N=19) exhibited significantly reduced P3a amplitudes compared with the low restorative group (N=20; t38=2.57; P=.02; d=0.59). Particularly, a moderate but significant negative correlation was found between the self-reported restorativeness scores and the P3a amplitudes at the fronto-central region (r=−.38; P=.02). However, the latency of the MMN/P3a complex did not significantly differ between the 2 groups (auditory mismatch negativity: t38=−1.47; P=.15 and P3a: t38=−0.31; P=.76).

CONCLUSIONS

Considering individuals’ restorative experience, the amplitude of the fronto-central MMN/P3a complex can potentially be employed as a distinct ERP component of interest in involuntary attention restoration during virtual nature experience in healthy young adults. The findings for the 360° virtual nature experience seem to be consistent with those of previous ERP studies on the effects of meditation practice. This study extends the findings of previous ART and ERP studies of real-world meditation, restoration, and mental fatigue management into the virtual world created by mobile phone–based VR glasses and 360° video content.