bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biologics for Rotator Cuff Repair
Authors: Smith Kevin M. , Le Adrian D.K. , Costouros John G. , Dragoo Jason L. 
Published: October 2018

* The complexity of tendon to bone healing in a rotator cuff surgical procedure has led to the investigation of biologic augmentation such as platelet-rich plasma, stem cells, and biomaterials to enhance the healing environment and to decrease the prevalence of failure.* Among the many types of biologic augmentation, there is considerable heterogeneity of the content, quality, and quantity of growth factors used in platelet-rich plasma and bone marrow aspirate concentrate, and conclusions from individual studies may not necessarily be generalizable to other formulations within the group.* Current Level-I evidence suggests that universal use of platelet-rich plasma provides no significant clinical benefit in rotator cuff repair.* Although some evidence exists for the use of stem cells from bone marrow aspirate concentrate and the use of biologic grafts, results from Level-I studies are lacking.* Level-I trials focused on the evaluation of clinical outcomes (i.e., American Shoulder and Elbow Surgeons [ASES] score, University of California at Los Angeles [UCLA] shoulder score, Constant score, Simple Shoulder Test) should be performed to help to determine the appropriate use of biologic augmentation in rotator cuff surgical procedures.
Hand Planter for the Developing World: Factor Testing and Refinement
Authors: Dhillon Jagmandeep S. , Omara P. , Nambi E. , Eickhoff E. , Oyebiyi F. , Wehmeyer G. , Fornah A. , Ascencio E. N. , Figueiredo B. M. , Lemings R. , Lynch T. , Ringer J. , Kiner W. , Taylor R. K. , Raun W. R. 
Published: October 2018

Core Ideas
Developing world maize producers desperately need better planting methods.
OSU hand planter delivers safety, convenience, and increased maize yields for producers managing highly marginal landscapes.
Same area of maize planted in the USA (30 million ha) is planted in the developing world on highly marginal slopes.
Maize (Zea mays L.) production in the developing world takes place on marginal landscapes using indigenous planting methods that conflict with modern hybrids, and the chemically treated seeds being used. In 1987, a mechanical planter was imagined that could replace indigenous planting methods used in many developing countries where maize is produced on marginal landscapes. Over two decades, controlled variables were evaluated with the aim of delivering an improved planter capable of singulating maize seed with each planter strike, and that would ensure uniform plant stands. This hand planter, presently termed GreenSeeder was further designed to deliver mid‐season fertilizer N via the use of an alternative internal drum. To secure singulation for each planter strike, many seed sizes, planter weights, brush strengths, drum cavity sizes, and operators were evaluated. Results showed that when seed size was large (<3000 seeds kg−1) and the 260‐20 internal drum was employed, the ability to singulate with no misses was high. When the 450S internal drum was used, seed sizes that were smaller (>3500 seeds kg−1) had higher singulation and lower misses. An efficiency index encumbering these parameters was developed that was highly correlated with final grain yield. In‐country design and manufacturing should account for ranges in seed size that work with the present design, drum cavity depth, and angle. Because this planter can easily accommodate mid‐season fertilizer N application, adoption of this device should deliver increased grain yields and fertilizer N use efficiency.
Coefficient of Variation from Vegetation Index for Sugarcane Population and Stalk Evaluation
Authors: Chanda Saoli , Kanke Yumiko , Dalen Marilyn , Hoy Jeffrey , Tubana Brenda 
Published: October 2018

Core Ideas
Variety and planting material affect cane population and millable stalk production.
Coefficient of variation from sensor readings decreases as cane canopy closes.
Cane varieties for sugar and energy production differ greatly in canopy structure.
Canopy structure influences sensor‐based profiling of cane population and stalk.
Coefficient of variation (CV) is a statistical measure of variability in data. This study was conducted to evaluate the relationship of CV computed from Vegetation Indices (VIs) with plant population and millable stalk of different sugarcane (Saccharrum spp.) varieties. Two experiments consisted of six cane varieties and two types of planting material (whole stalks vs. billets) with four replications arranged in a split plot in randomized block design were established in St. Gabriel, LA, in 2012 and 2013. Sensor readings were concurrently collected with plant population at 4 and 8 weeks after planting (WAP) and tiller count at early and late tillering stage. Variety had a more evident, consistent effect than planting material on population count, tiller number, and millable stalk (p < 0.001). The regression analysis revealed: (i) a positive linear relationship between NDVI660 and CV660 with coefficient of determination (r2) of 0.49*** at 4 WAP, then changed to negative linear at 8 WAP and early tillering stage with r2 values of 0.52*** and 0.75***, respectively; and (ii) CVs and VIs from the red‐edge band had consistently negative linear relationships (p < 0.001), the strongest being at the early tillering stage (r2 = 0.61–0.73). The linear relationship of CV with plant population and millable stalk improved when variety was included as categorical variable. Future research should focus to categorize varieties into broader group based on canopy structure to develop more refined CV‐based model for fast profiling of cane plant stand population, tiller production, and millable stalk.
Implantable cardioverter–defibrillator in hypertrophic cardiomyopathy
Authors: Sanchez Diego Jimenez , Lozano Ignacio Fernández 
Published: October 2018

Sudden cardiac death (SCD) is the most devastating complication in hypertrophic cardiomyopathy (HCM). The implantable cardioverter–defibrillator (ICD) has proven to be effective in SCD prevention in several clinical scenarios. In HCM population, it has demonstrated to successfully abort life-threatening ventricular arrhythmias despite the extreme morphology characteristic of HCM, often with massive degrees of left ventricular hypertrophy and/or LV outflow tract obstruction. Studies showed a high rate of appropriate intervention in secondary prevention and in primary prevention of patients considered at high risk. This appropriate intervention rate is even more significant considering the young and otherwise healthy patients that compose HCM population. Since SCD incidence in HCM is relatively low, optimal identification of patients at high risk is crucial. Classical strategy of risk stratification based on clinical risk factors has several limitations and has proven to overestimate risk. A new risk prediction model that provides individual 5-year estimated risk appears to be superior to traditional models based on bivariate risk factors. Perioperative complications seem to be similar to those related to the implant of other cardiac devices, while long-term complications have been traditionally in the spotlight. HCM patients are considered more vulnerable to ICD-related complications and inappropriate ICD therapy because of their young age at implant and increased prevalence of atrial fibrillation, but long-term follow-up data on ICD-related complications in general practice is limited. The subcutaneous implantable cardioverter defibrillator seems to be a safe and effective alternative in HCM, although long-term data are scarce.
Rapid-Acting Antidepressants
Authors: Witkin Jeffrey M. , Knutson Daniel E. , Rodriguez Gabriel J. , Shi Samuel 
Published: October 2018

Background:
Conventional antidepressants are thought to produce their impact on clinical symptoms
by increasing the central availability of biogenic amine neurotransmitters (the monoamine hypothesis of depression).
These drugs continue to be the primary medicines used in major depressive disorder. Although they have
biological effects after acute dosing, full antidepressant response generally takes weeks of daily administration.
Lack of rapid onset is a large limitation in antidepressant therapy (e.g., suicide, lack of medication compliance,
difficulty switching medications).

Methods:
The present review of the literature discusses the preclinical and clinical findings on compounds that
can produce immediate symptom relief.

Results:
These compounds include ketamine, scopolamine, and mechanistically-related drugs. Newer additions to
the list of potential rapid-acting agents include antagonists of metabotropic (mGlu) 2/3 receptors, negative allosteric
modulators of α5-containing GABAA receptors, and psychedelic compounds. An additional benefit of these
compounds is that they have demonstrated large effect sizes and, importantly, demonstrated efficacy in patient’s
refractory to other treatments. A drawback of some of these compounds, to date, is finding ways to expand the
duration of clinical efficacy. In addition, for some compounds, the side-effect profile requires management. A
primary mechanism by which rapid effects might be produced is through the amplification of excitatory neurotransmission
through activation of AMPA receptors. The extracellular efflux of glutamate induced by these drugs
has been documented and provides the hypothesized triggering mechanism for AMPA receptor amplification.

Conclusion:
The preclinical and clinical literature strongly suggests that rapid-acting antidepressants are the
current focus of antidepressant drug discovery. Promising clinical findings exist for several compounds including
ketamine and other NMDA receptor antagonists, scopolamine, and psilocybin. Two compounds are in late stage
clinical development: GLYX-13 (Rapastinel) and eskekamine.
Enterobacter Hormaechei: New Neonatal Infection in Morocco
Authors: Dyabi F.Z. , Bennaoui F. , Slitine N. El Idrissi , Soraa N. , Maoulainine F.M.R 
Published: October 2018

Introduction:
Enterobacteria are gram-negative bacilli, found in soil, water, and especially in humans and animals gut. They include a very large number of genera and species, often involved in human clinical specimens, predominately E. cloacae and E. aerogenes. Enterobacter hormaechei was suggested in 1989 as a new member of enterobacter family, during the last twenty years they were responsible for nosocomial infection in hospitalized adult patients, some information is available on their virulence-associated properties. They are very rare in the newborn.

Case Reports:
We report five cases of E. hormaechei's infection; first case in our department: neonatal ICU, at Mohamed VI University Hospital, Marrakesh, Morocco. Five newborns were aged between eight hours and ten days, two of them were from multiple pregnancies, and gestational age was less than 36 weeks in three cases. Clinical presentation was variable and respiratory distress was found in four patients as the most frequent sign. Multidrug-resistant E. hormaechei was isolated from the blood culture in all cases. One newborn showed on his second day of life a cutaneous necrosis, the necrosis's swab culture isolated also an E. hormaechei. Patients were treated by the combination of Tienam and Amikacine. The progress was favorable in two patients. However, three of our patients died.

Results:
We found that E. hormaechei can be responsible for nosocomial infection in vulnerable patients. It can be transferred between patients when hygiene measures are not respected.
Association Between STAT4 rs7574865 Polymorphism and Rheumatoid Arthritis: Debate Unresolved
Authors: Tarakji Iman , Habbal Wafa , Monem Fawza 
Published: October 2018

Background:

STAT4 rs7574865 polymorphism has been evidently associated with susceptibility to Rheumatoid Arthritis (RA) in European and Eastern Asian populations, whereas studies in other countries reported otherwise.

Objective:
We investigated the distribution of STAT4 rs7574865 polymorphism in a group of Syrian RA patients.

Methods:
Eighty-one RA patients and forty healthy controls were enrolled and STAT4 rs7574865 was genotyped by direct sequencing. RA patients were stratified according to Anti-Citrullinated Protein Antibodies (ACPA) status for analysis.

Results:
Minor T allele frequencies were 30.4%, 16.7%, and 23.8% in ACPA-positive RA patients, ACPA-negative RA patients, and healthy controls, respectively. No significant differences in STAT4 rs7574865 allele/genotype frequencies were found between ACPA-positive RA patients, ACPA-negative RA patients, and healthy controls (P>0.05).

Conclusion:

STAT4 rs7574865 TT genotype showed a potential impact on ACPA positivity in Syrian RA patients. However, STAT4 rs7574865 effect on RA onset and severity is minor compared to other genetic factors such as HLA-DRB1 shared epitope alleles.
Using Tibia Proximal Cut Autograft in Advanced Varus Knee Deformity in Total Knee Arthroplasty; Outcomes Compared to the Control Group
Authors: Arslan Aydin 
Published: October 2018

Background:The purpose of this study was to compare the outcomes of Total Knee Arthroplasty (TKA) performed for advanced varus knee deformity, which is performed by using tibia proximal cut bone for the reconstruction of the tibia proximal medial bone defects, with a control group consisting of TKAs which did not need reconstruction.Methods:Patients in the present study underwent total knee arthroplasty between 2009 and 2015. 12 patients with advanced varus deformity who had undergone reconstruction with tibia proximal cut autograft and 15 patients who were randomly selected from patients who did not need reconstruction, were compared clinically and radiographically.Results:The mean follow-up period of the patients was found to be 73.1 ± 19.7 (36-108) months in the reconstruction group and 73.2 ± 12.3 (39-107) months in the control group. (p> 0.05) In both groups, significant improvement was observed postoperatively. In both groups, there was no evidence of loosening the required revision. WOMAC score was 32.4 ± 13.3 (8-64) in the reconstruction group and 28.9 ± 17.2 (6-70) in the control group at the last control visit. There was no difference between the groups when comparing the WOMAC scores at the last control visit. In the reconstruction group, the Hip-Knee-Ankle (HKA) angle was 26.1 ± 4.9 ° varus preoperatively and 1.3 ± 2.3 ° valgus postoperatively; and in the control group 10.1 ± 2.1 ° varus preoperatively and 2.7 ± 3.4 ° valgus postoperatively. (p> 0.05)Conclusion:In the present study, clinical and radiographic results of total knee arthroplasty patients, who suffered from advanced knee varus deformity and whose proximal tibia medial defects were reconstructed by using tibial proximal cut autograft, have been found to be successful when compared to the control group.
Regulator-Cited Cooperation Credit and Firm Value: Evidence from Enforcement Actions
Authors: Files Rebecca , Martin Gerald S. , Rasmussen Stephanie J. 
Published: October 2018

ABSTRACT
Regulators claim to reward firm cooperation in the enforcement process. However, critics question which actions constitute firm cooperation and contend that cooperation leads to “harsh” and “unfair” outcomes. Examining 1,162 enforcement actions for financial misrepresentation initiated by the Securities and Exchange Commission and Department of Justice, we find that regulator-cited cooperation credit is best explained by remedial actions and self-reported law violations. Cooperation credit is negatively associated with firm monetary penalties assessed by regulators. Our estimates suggest that firms with cooperation credit realize an average penalty reduction of $23.8 million (49 percent). We also estimate that average reputation-related losses are $756 million (70 percent) lower for firms with cooperation credit. We find no association between cooperation credit and related private action outcomes. Our results provide important insight into what constitutes meaningful cooperation with regulators, and suggest that the benefits can be substantial for firms deemed to be cooperative.
JEL Classifications: G38; K22; K42; M41.
HUBUNGAN SIKAP TERHADAP PENGETAHUAN SISWA PADA MATERI SISTEM PERNAPASAN MANUSIA DI KELAS XI IPA SMA NEGERI 3 BINJAI TAHUN PEMBELAJARAN 2017/2018
Authors: Romaisyah Siti , Hasairin Ashar , Siregar Veriati 
Published: October 2018

This study aims to determine students’ knowledge, attitudes of students, attitude relationships to students' knowledge and their contribution to the Human Respiratory System material in class XI IPA SMA Negeri 3 Binjai in Academic Year 2017/2018. The population of this study is all students of class XI IPA SMA Negeri 3 Binjai which consisting of five classes amounted to 190 students. The sample of research consisted of two classes namely XI IPA1 and XI IPA4 as many as 75 students and sampling was done by random sampling technique. The type of research is correlational research. The research instrument used is 25 questions of knowledge test and 30 questions of questionnaire. The results showed that students' knowledge on Human Respiratory System material in class XI IPA SMA Negeri 3 Binjai in Academic Year 2017/2018 is in enough category with the average score of 67.15. Students' Attitudes on Human Respiratory System Material in grade XI IPA SMA Negeri 3 Binjai in Academic Year 2017/2018 is in a pretty good category with the average score of 77.96. Attitude relationship to student's knowledge on Human Respiratory System material including high category (r = 0,662). Contribution of attitude to the students knowledge of 43.82% and hypothesis test results show that there is a significant relationship between attitudes toward student knowledge on the Human Respiratory System material.Keywords: knowledge, attitude, human respiratory system
PERBEDAAN HASIL BELAJAR DAN AKTIVITAS SISWA MENGGUNAKAN MODEL PEMBELAJARAN KOOPERATIF TIPE JIGSAW DENGAN NHT PADA MATERI SISTEM PERNAPASAN MANUSIA
Authors: Utami Risa , Sinaga Erlintan , Dongoran Herawati 
Published: October 2018

Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar dan aktivitas siswa menggunakan model pembelajaran kooperatif tipe Jigsaw dengan NHT pada materi sistem pernapasan manusia di kelas XI IPA MAN 1 Medan T.P 2017/2018. Jenis penelitian ini adalah penelitian eksperimen semu. Sampel dalam penelitian ini terdiri dari 2 kelas yaitu kelas XI IPA2 menggunakan model pembelajaran kooperatif tipe Jigsaw dan kelas XI IPA4 menggunakan tipe NHT. Hasil analisis data menunjukkan rata-rata hasil belajar menggunakan model Jigsaw sebesar 79,78 dengan SD 8,50 dan hasil belajar model Numbered Head Together (NHT) sebesar 85,52 dengan SD 7,98. Nilai aktivitas siswa pada kelas Jigsaw diperoleh sebesar 84,67 diklasifikasikan dalam kategori baik dengan nilai SD 9,26, sedangkan nilai aktivitas siswa pada kelas NHT diperoleh sebesar 88,29 diklasifikasikan dalam kategori sangat baik dengan SD 7,68. Analisis hasil belajar menggunakan uji-t pada taraf signifikan 0,05, diperoleh thitung > ttabel (3,48 > 1,665) sehingga dalam penelitian ini hipotesis nol (H0) ditolak dan hipotesisi alternative (Ha) diterima, analisis aktivitas siswa dengan menggunakan uji-t pada taraf signifikan 0,05, diperoleh thitung > ttabel (2,13 > 1,665) maka Ha diterima dan H0 ditolak, dengan demikian diperoleh kesimpulan bahwa ada perbedaan hasil belajar dan aktivitas siswa menggunakan model pembelajaran kooperatif tipe Jigsaw dengan NHT pada materi sistem pernapasan manusia di kelas XI IPA MAN 1 Medan T.P 2017/2018. Kata kunci : Hasil belajar, aktivitas siswa, Jigsaw, NHT (Numbered Head Together).
Mancala in Surinamese Maroon Communities: The Expedition of Melville J. Herskovits
Authors: Okoshi Akane , de Voogt Alex 
Published: October 2018

Abstract
The American Museum of Natural History (amnh) has three mancala game boards in their collection that are connected with Suriname, formerly Dutch Guyana. One of these samples is exhibited in the amnh African Peoples Hall as part of a section on African Slavery and Diaspora. The games of Suriname were described by Melville J. Herskovits in an article dating to 1929, but the relation of these three boards with Herskovits has remained unclear. With the help of the Herskovits archives, the archival records of amnh and recent research on Surinamese Maroon communities, the history of these three boards is shown to be intimately linked with Herskovits’ broader intellectual project.
The distribution ofSalvinia natans(L.) All. in the Odra and the Oława River valleys in Wrocław area (Poland)
Authors: Pietryka Mirosława , Richter Dorota , Podlaska Magda 
Published: October 2018

AbstractThe data presented in this paper concern the occurrence ofSalvinia natans(L.) All. in Wrocław area. Field research was conducted in the vegetation season (June-September) between 2013 and 2017 in water bodies (natural and artificial), in the main river beds of the Oława and the Odra Rivers and in the Odra canals in Wrocław. The study provided 32S. natanslocations in the city area. The studied species occurred in various plant communities accompanied by numerous species which were also under protection, increasing the ecological value of the habitats. Additionally, a stableS. natanssite was confirmed by the study in a location where aquatic fern had previously been recorded in Wrocław. The research indicates numerous populations of the species along the Odra and the Oława and in many old river beds and artificial water bodies in Wrocław and the results confirm the visible trend of a growing number ofS. natanssites in all of Poland.
A Review of the Marine Crab Fisheries in the Turkish Seas
Authors: Harlıoğlu Muzaffer Mustafa , Farhadi Ardavan , Ateş Abdullah Suat 
Published: October 2018

Abstract
The paper presents a review of the distribution of marine crabs (Brachyura) along the Turkish coast and the amount of economically important marine crabs harvested between 1967 and 2016. Previous records reported that Turkey had 102 brachyuran crab species, only five of them being economically important, but this review identifies two more species, Inachus phalangium and Ashtoret lunaris. The Aegean Sea has more crab species than the Mediterranean, the Black Sea and the Sea of Marmara. The most harvested species are Callinectes sapidus, Maja squinado, Eriphia verrucosa, Carcinus aestuarii and Portunus segnis, respectively. This review shows that there have been fluctuations in the harvest of marine crabs between years, the lowest being 5 tonnes in 2015 and the highest, 2116 tonnes in 1984. The information provided in this review provides a basis for potential profitable development of conservation and management strategies of marine crabs in Turkey.