bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of academic stress and coping strategies among built environment undergraduate students in Nigerian higher education
Authors: Dada Joshua Oluwasuji , Babatunde Solomon Olusola , Adeleye Racheal Oluwatoyin 
Published: January 2019

Purpose
Stress has become an important topic in the academic environment. However, studies on academic stress among built environment students have received little attention. The purpose of this paper, therefore, is to assess the causes of academic stress, and its coping strategies among built environment undergraduate students in public higher education institution (HEI) in Nigeria.

Design/methodology/approach
An extensive literature review was conducted to identify the causes of academic stress and its coping strategies among the students in HEIs, using quantity surveying students as a case. Primary data were elicited through questionnaire survey administered on 189 quantity surveying students in Obafemi Awolowo University, Nigeria. A total of 169 copies of the questionnaire were returned and suitable for analysis. The data obtained were analyzed using the mean score and t-test.

Findings
The study identified 27 causes of students’ academic stress, and the analysis of the total ranking revealed that 8 out of 27 causes of academic stress were considered important. The results of t-test indicated that except for 5 out of 27 identified causes of student academic stress, there is no statistically significant difference in the perceptions of male and female students. The study further identified 30 coping strategies employed by students in dealing with academic stress, out of which six identified coping strategies were considered important. In addition, the results of t-test revealed that except for 11 out of 30 identified coping strategies, there is no statistically significant difference in the perceptions of male and female students surveyed.

Practical implications
The identification of the important causes of academic stress and its coping strategies among the students in the public higher education will be useful for the university management to formulate policies toward providing a well-balanced academic environment that is conducive to better learning. In addition, policy recommendations are proposed.

Originality/value
The findings will help the academic staff and university management to design and implement policies toward refining the teaching procedures in higher education. Also, this study would be of great value to academic staff and university administrators to develop a framework for incorporating stress coping strategies in the higher education curriculum. This study is important as not many empirical studies relating to academic stress and its coping strategies have been conducted in the built environment disciplines.
Plant geographic origin and phylogeny as potential drivers of community structure in root‐inhabiting fungi
Authors: Koyama Akihiro , Maherali Hafiz , Antunes Pedro M. 
Published: January 2019

Abstract

Root‐inhabiting fungal communities, including mutualists and antagonists, influence host plant performance, and can potentially shape plant community composition. However, there is uncertainty about how root‐inhabiting fungal communities are structured, and if fungal community characteristics are significant predictors of host plant abundance.

In this study, we first assessed how root‐inhabiting fungal communities were structured in relation to the phylogeny and geographic origins (native vs. exotic) of their host plants in an old‐field community. In addition, we took into consideration the spatial arrangements (i.e. physical locations) of the individual host plants. We then tested if the relative abundances of pathogenic and beneficial arbuscular mycorrhizal (AM) fungi could predict host plant abundances.

We found that host plant phylogeny was an important factor in structuring the whole fungal community, irrespective of host plant origin. Furthermore, the spatial arrangements of individual host plants were a strong predictor of AM fungal community structure. Host plant phylogeny and spatial arrangements appeared to similarly affect the structure of pathogenic fungal communities. No distinct differences were observed between native and exotic plant species in fungal community characteristics. The relative abundances of AM and pathogenic fungi were not significant predictors for observed abundances of their host plants.

Synthesis. Host plant phylogeny and spatial arrangements can structure naturally occurring root‐inhabiting fungal communities. The absence of distinct differences in fungal community composition, including pathogens, in exotic and native plants suggests long residence times and the consequent naturalization of exotic species in the region, allowing for the establishment of similar plant–microbial interactions between native and exotic species.
Spatial organization of the gene expression hardware in Pseudomonas putida
Authors: Kim Juhyun , Goñi‐Moreno Angel , Calles Belén , de Lorenzo Víctor 
Published: January 2019

SummaryThe localization of ribosomes, RNA polymerase (RNAP) and the nucleoid of Pseudomonas putida cells has been inspected with genetic, microscopical and physiological approaches. To this end, strains of P. putida were constructed with fluorescent tags to either ribosomal proteins or the RNAP or both. Their relative positions in respect to the bacterial DNA revealed the separation of the ribosomal pool from the nucleoid, which however co‐localized entirely with the tridimensional distribution of RNAP. This split was kept under all growth conditions: exponential versus stationary and different carbon sources. To test the robustness of what appeared to be a phase separation phenomenon, different types of perturbations were entered. In one case, cells were grown under conditions known to accumulate polyhydroxyalkanoate granules that caused a mechanical impact in the cytoplasm – which failed to destroy the split between the translation versus transcription machineries. However, both chloramphenicol and rifampicin blurred – but not eliminated – the boundaries between the phases. The picture that emerges from all these data is not only that the different components of the gene expression hardware are physically divided but also that a large share of the mRNAs ought to move from their site of transcription towards ribosome‐rich regions of the cell.
Patterns of geographic variation between mitochondrial and nuclear markers in Heaviside's (Benguela) dolphins (Cephalorhynchus heavisidii)
Authors: GOPAL Keshni , KARCZMARSKI Leszek , TOLLEY Krystal A. 
Published: January 2019

AbstractThe Heaviside's (or Benguela) dolphin (Cephalorhynchus heavisidii) is endemic to the west coast of southern Africa. The present study investigated the population genetic structure across a large portion of the species distribution using mitochondrial control region and nuclear (microsatellite) markers. A total of 395 biopsy skin samples were analyzed; they were collected from free‐ranging Heaviside's dolphins in 7 locations along 1650 km of coast between Table Bay, South Africa and Walvis Bay, Namibia. Both genetic markers rejected the hypothesis of 1 homogenous population but revealed contrasting results in the genetic structuring of putative populations. Mitochondrial DNA suggested either 2 populations or a fine‐scale division with 6 (sub) populations, while microsatellite markers were indicative of 2 widespread populations with measurable gene flow between them. Neutrality tests and mismatch distribution of the mitochondrial sequences indicated a departure from mutation–drift equilibrium due to a population expansion at the 2 extremes of the geographic range, but not towards the middle of the distribution. These results highlight the importance of evaluating multiple genetic markers to gain reliable insights into population processes and structure.
The Design of Environmental Priorities in the SDGs
Authors: Elder Mark , Olsen Simon Høiberg 
Published: January 2019

AbstractThis article argues that the environment was extensively incorporated into the Sustainable Development Goals (SDGs), with broad and ambitious targets, reflecting environmental concerns throughout the SDGs. Many environment‐related targets – including some of the most important ones – were placed under ‘non‐environmental’ goals. The SDGs also adopted the view that economic growth can be made environmentally sustainable using ‘decoupling’ and ‘resource efficiency’ as key technological solutions. Governments rejected a more transformative objective ‘beyond GDP’, the concept of planetary boundaries, and strong implementation mechanisms. Most disappointing, the environmental elements in many targets were not included in indicators, or the indicators lacked ambition, or were watered down. Key factors in achieving the strong and integrated approach to environment and development at the level of goals and targets were: (1) the role of new ideas on the importance of the environment and an integrated approach to sustainable development which was promoted by the science and research community; (2) a group of norm entrepreneurs, who promoted these ideas; and (3) the institutional structure and working modalities of the Open Working Group (which drafted the text of the SDGs) whose special characteristics facilitated the final agreement. The dilution of the indicators resulted from a very different institutional structure and process with different actors and from the development focused legacy of the Millennium Development Goals (MDGs) that had not resulted in sufficient capacity for thoroughly measuring environmental concerns.
Power, Politics and Knowledge Claims: Sexual and Reproductive Health and Rights in the SDG Era
Authors: Yamin Alicia Ely 
Published: January 2019

AbstractThe selection of Sustainable Development Goals (SDGs) , targets and indicators for sexual and reproductive health and rights (SRHR) can only be understood in the light of struggles to advance these rights amid a context of the growing reliance on indicators to measure progress. If the Millennium Development Goals (MDGs) de‐politicized inherently polemical issues in SRHR, the (re)production of knowledge of rights in the SDGs poses a subtler, but just as serious, threat. Although rights, and SRHR in particular, are apparently taken into account, the apparent neutrality of these metrics obscures politics and ideology. There is a danger that over‐reliance on quantitative indicators obscures the structural challenges facing the advancement of SRHR, and therefore indicators should be coupled with qualitative information derived in context.
The Sustainable Development Goals Confront the Infrastructure of Measurement
Authors: Merry Sally Engle 
Published: January 2019

AbstractThis brief article comments on the special issue on SDGs ‐ Knowledge and Politics in Setting and Measuring the SDGs. Acknowledging that the articles in the issue show how reliance on indicators changes the way development is conceived, Merry asks why is it so difficult to produce better indicators. If they are too narrow, why not simply produce more? She argues that conceiving of measurement as an infrastructure provides important insight into these questions.
Objectivity as Distance or Engagement: The Riddle of SDG Measurement
Authors: Lehohla Pali 
Published: January 2019

AbstractWhat is objectivity in SDG measurement? This commentary explores the complexity of objectivity in measurement when the problems are ‘global’ yet manifest themselves with local specificities. This special issue helps elicit gaps in knowledge, tools and contexts in SDG measurement. But in doing so through the lens of political economy, ‘sets the cat among the pigeons’. The key question they raise is the sanitization of measurement and its sanctification to the status of objectivity without realizing that the process is fraught with contexts that make self‐ interest and conflict of interest an endemic risk.
Layers of Politics and Power Struggles in the SDG Indicators Process
Authors: Kapto Serge 
Published: January 2019

AbstractThe process of designing the 2030 Agenda for Sustainable Development was intensely political, as it can be expected of United Nations negotiations of that magnitude. Inevitably, those politics have spilled over into the technical process of formulating global indicators to monitor the Sustainable Development Goals. This commentary explores some of the tensions between competing priorities and various constituencies that affect the design of the global SDG indicator framework.
General hospital admission rates in people diagnosed with personality disorder
Authors: Fok M. L.‐Y. , Chang C.‐K. , Broadbent M. , Stewart R. , Moran P. 
Published: January 2019

ObjectiveTo determine the frequency of all‐cause general hospital admissions for individuals with personality disorder (PD) in a large clinical population using linked secondary mental healthcare and hospitalisation data.MethodA retrospective cohort study, using anonymised electronic mental health records from South London and Maudsley NHS Foundation Trust (SLaM), linked to Hospital Episodes Statistics in England. People with PD aged 15 years or older, receiving care within SLaM between April 2007 and March 2013, were identified and compared to residents from the local catchment area. Standardised admission ratios (SARs) were calculated for all major categories of causes of general hospital admission for this defined group, with local residents in 2011 UK Census as the standard population.ResultsFor the 7677 people identified with PD, SAR for all causes of admission was 2.75 (95% CI: 2.70, 2.81). Both men and women with PD had increased SARs across multiple ICD‐10 categories, including circulatory, respiratory, digestive, nervous, and musculoskeletal system disorders and endocrine, blood and infectious disorders. Sensitivity analysis (removing the impact of repeated admissions by same individual for same diagnosis in the same year) yielded similar findings.ConclusionsBy comparison with members of the general population, individuals with a diagnosis of personality disorder are at significantly higher risk of hospital admission resulting from a wide range of physical health problems.
Low hepatitis B surface antigen and HBV DNA levels predict response to the addition of pegylated interferon to entecavir in hepatitis B e antigen positive chronic hepatitis B
Authors: Liem Kin Seng , van Campenhout Margo J. H. , Xie Qing , Brouwer Willem Pieter , Chi Heng , Qi Xun , Chen Liang , Tabak Fehmi , Hansen Bettina E. , Janssen Harry L. A. 
Published: January 2019

SummaryBackgroundVarious treatment combinations of peginterferon (PEG‐IFN) and nucleos(t)ide analogues have been evaluated for chronic hepatitis B (CHB), but the optimal regimen remains unclear.AimsTo study whether PEG‐IFN add‐on increases response compared to entecavir (ETV) monotherapy, and whether the duration of ETV pretreatment influences response.MethodsResponse was evaluated in HBeAg positive patients previously treated in two randomized controlled trials. Patients received ETV pretreatment for at least 24 weeks and were then allocated to 24‐48 weeks of ETV+PEG‐IFN add‐on, or continued ETV monotherapy. Response was defined as HBeAg loss combined with HBV DNA <200 IU/mL 48 weeks after discontinuing PEG‐IFN.ResultsOf 234 patients, 118 were assigned PEG‐IFN add‐on and 116 continued ETV monotherapy. Response was observed in 38/118 (33%) patients treated with add‐on therapy and in 23/116 (20%) with monotherapy (P = 0.03). The highest response to add‐on therapy compared to monotherapy was observed in PEG‐IFN naive patients with HBsAg levels below 4000 IU/mL and HBV DNA levels below 50 IU/mL at randomization (70% vs 34%; P = 0.01). Above the cut‐off levels, response was low and not significantly different between treatment groups. Duration of ETV pretreatment was associated with HBsAg and HBV DNA levels (both P < 0.005), but not with response (P = 0.82).ConclusionsPEG‐IFN add‐on to ETV therapy was associated with higher response compared to ETV monotherapy in patients with HBeAg positive CHB. Response doubled in PEG‐IFN naive patients with HBsAg below 4000 IU/mL and HBV DNA below 50 IU/mL, and therefore identifies them as the best candidates for PEG‐IFN add‐on (Identifiers: NCT00877760, NCT01532843).
Letter: impact of Epstein‐Barr virus serological status on clinical outcomes in adult patients with inflammatory bowel disease – authors' reply
Authors: de Francisco Ruth , Castaño‐García Andrés , Riestra Sabino 
Published: January 2019

Linked ContentThis article is linked to de Francisco et al and Ahmed et al papers. To view these articles, visit https://doi.org/10.1111/apt.14933 and https://doi.org/10.1111/apt.15104.
Dual‐hemostat port closure technique with customized surgical suture after laparoscopic cholecystectomy: Single‐center experience
Authors: Kawai Hironari , Misawa Takeyuki , Sasaya Kazuto , Aoyama Yoshishige 
Published: January 2019

IntroductionDual‐hemostat techniques for port closure have previously been reported, but their safety and efficacy have not been evaluated. Here, we describe the dual‐hemostat port closure technique employed at our institution, which uses a customized surgical suture for safe and certain port closure, and we assess the incidence rate of trocar‐site hernia (TSH) after laparoscopic cholecystectomy.MethodsFrom March 1999 to March 2017 at our institution, 316 patients underwent elective laparoscopic cholecystectomy performed by a single experienced surgeon. We routinely used a dual‐hemostat technique with a customized surgical suture to achieve safe and certain port closure. We assessed the incidence rate of TSH after laparoscopic cholecystectomy (defined as a reoperation for a TSH or clinical hernia at the port site) based on follow‐up data from patient questionnaires and clinical examinations.ResultsAfter 67 patients were excluded because of death, unknown address, or conversion to open cholecystectomy, 249 eligible patients received questionnaires, of which 173 were returned (response rate, 69.5%). From these responses, TSH was suspected in three patients, but only one underwent reoperation for TSH after laparoscopic cholecystectomy. Thus, the incidence rate of TSH after laparoscopic cholecystectomy was 0.6% (1/173).ConclusionsOur single‐center experience demonstrated that our port closure technique using a dual‐hemostat technique with customized surgical suture provides an appropriate option for laparoscopic cholecystectomy, especially given its ease and low incidence of TSH.
Debate: Pediatric bipolar disorder – the elephant in the room
Authors: Duffy Anne 
Published: January 2019

Read the Editors’ introduction at: doi: 10.1111/camh.12315Read the core debate at: doi: 10.1111/camh.12231; doi: 10.1111/camh.12243; doi: 10.1111/camh.12296; doi: 10.1111/camh.12306Read more perspectives in this debate at: doi: 10.1111/camh.12318 doi: 10.1111/camh.12317; doi: 10.1111/camh.12313; doi: 10.1111/camh.12310; doi: 10.1111/camh.12314
A combined drug discovery strategy based on machine learning and molecular docking
Authors: Zhang Yanmin , Wang Yuchen , Zhou Weineng , Fan Yuanrong , Zhao Junnan , Zhu Lu , Lu Shuai , Lu Tao , Chen Yadong , Liu Haichun 
Published: January 2019

AbstractData mining methods based on machine learning play an increasingly important role in drug design and discovery. In the current work, eight machine learning methods including decision trees, k‐Nearest neighbor, support vector machines, random forests, extremely randomized trees, AdaBoost, gradient boosting trees, and XGBoost were evaluated comprehensively through a case study of ACC inhibitor data sets. Internal and external data sets were employed for cross‐validation of the eight machine learning methods. Results showed that the extremely randomized trees model performed best and was adopted as the first step of virtual screening. Together with structure‐based virtual screening in the second step, this combined strategy obtained desirable results. This work indicates that the combination of machine learning methods with traditional structure‐based virtual screening can effectively strengthen the ability in finding potential hits from large compound database for a given target.
Lost at high latitudes: Arctic and endemic plants under threat as climate warms
Authors: Niskanen Annina Kaisa Johanna , Niittynen Pekka , Aalto Juha , Väre Henry , Luoto Miska 
Published: January 2019

AbstractAimSpecies’ biogeographical patterns are already being altered by climate change. Here, we provide predictions of the impacts of a changing climate on species’ geographical ranges within high‐latitude mountain flora on a sub‐continental scale. We then examined the forecasted changes in relation to species’ biogeographic histories.LocationFennoscandia, Northern Europe (55–72°N).MethodsWe examined the sensitivity of 164 high‐latitude mountain species to changing climate by modelling their distributions in regard to climate, local topography and geology at a 1 km2 resolution. Using an ensemble of six statistical modelling techniques and data on current (1981–2010) and future (2070–2099) climate based on three Representative Concentration Pathways (RCPs 2.6, 4.5, 8.5), we developed projections of current and future ranges.ResultsThe average species richness of the mountain flora is predicted to decrease by 15%–47% per 1 km2 cell, depending on the climate scenario considered. Arctic flora is projected to undergo severe range loss along with non‐poleward range contractions, while alpine flora is forecasted to find suitable habitat in a warmer North. A substantial majority (71%–92%) of the studied species are projected to lose more than half of their present range by the year 2100. Species predicted to lose all suitable habitat had ranges centred in the northernmost (>68°N) part of continental Europe.Main conclusionsClimate change is predicted to substantially diminish the extent and richness of Europe's high‐latitude mountain flora. Interestingly, species' biogeographic histories affect their vulnerability to climate change. The vulnerability of true Arctic and endemic species marks them as highly important for conservation decisions.
Equine retrobulbar disease: Diagnoses and outcomes of 15 horses with exophthalmos (1988–2017)
Authors: Knickelbein K. E. , Holmberg B. J. , Lassaline M. E. 
Published: January 2019

SummaryRetrobulbar disease, while rare in horses, can pose a clinical challenge due to the advanced diagnostic procedures necessary to determine the underlying aetiology and extent of disease. The goal of this study was to explore definitive causes of exophthalmos within a hospital population and investigate prognoses for the various aetiologies. Retrospective medical record review was used to identify 15 horses diagnosed with a definitive cause of exophthalmos. Patient signalment, disease duration, eye affected, diagnostic procedures, therapies, and histopathological diagnosis were evaluated. Geldings (12/15, or 80%) were over‐represented (P = 0.014). Mean age at presentation (14 ± 6.7 years) was not significantly different for horses with (14 ± 8.5 years) and without (15 ± 4.4 years) a diagnosis of neoplasia. Diagnosis of a neoplastic process was made in 8/15 horses (53.3%) with neuroendocrine tumour being most common. Eight of the 15 cases were classified as primary orbital disease, and seven represented extension from paranasal sinus disease. Two novel diagnoses were identified: cystic hamartoma arising from the lacrimal gland and orbital aspergillosis secondary to sinonasal disease. In total, eight of 12 horses for which follow‐up was available were euthanised due to orbital disease, two immediately following computed tomography of the skull and six due to disease progression. One horse was euthanised following a peri‐anaesthetic complication. Three horses were lost to follow‐up. Of the 12 horses for which follow‐up was available, only four (33.3%) were alive 21 months post‐diagnosis. Considering only patients for whom a definitive diagnosis was obtained, retrobulbar disease was associated with a poor prognosis for life.