bluuebunny/crossref_metadata_2025_split huggingface dataset:
Propuesta de un nuevo modelo: Práctica Reflexiva Mediada
Authors: Cerecero Medina Ingrid Eugenia 
Published: June 2018

Esta investigación se focalizo en encontrar la pertinencia de la combinación de elementos para que docentes en activo y con experiencia, lleven a cabo ciclos de práctica reflexiva aplicados a su propia labor como medio de mejora y evaluación de la misma. Se tomaron como punto de partida tres fundamentos para la propuesta: 1) La relación dialógica entre la teoría y la práctica, 2) algunos modelos y características de la práctica reflexiva mencionadas por distintos autores; y 3) la relevancia del apoyo de la mediación.Se exponen, en un primer momento, la importancia de la teoría y la práctica para el análisis de la labor docente, seguido de algunas de las características principales de la práctica reflexiva; algunas notas relevantes sobre la teoría sociocultural de Vygotsky, la mediación y el modelo propuesto por Engeström para la teoría de la actividad; así como la presentación de ciertos modelos representativos de la práctica reflexiva dando como resultado la propuesta de un nuevo modelo al que hemos llamado Práctica Reflexiva Mediada, resumiendo los elementos que lo constituyen y su conceptualización. El modelo fue aplicado a docentes de lenguas por medio de un taller y el seguimiento de registros y observaciones de su práctica en un período de dos meses. Tiempo durante el cual los docentes tuvieron la oportunidad de interactuar y llevar a la práctica cada uno de los estadios del modelo, los cuales se dividen en tres: conocimiento, significación y resignificación, siendo acompañados de un mediador y sus pares. Entre los resultados encontrados se destaca la importancia de la participación de un mediador que apoye dicho proceso y el compromiso de los docentes para llevarlo a cabo, reconociendo que las experiencias y saberes de los docentes pueden compartirse y documentarse originando la posibilidad de encontrar nuevos supuestos a comprobar.
El método R5 de Práctica Reflexiva. Evaluación de su impacto en la formación inicial de maestros
Authors: Roget Angels Domingo 
Published: June 2018

Partiendo de la investigación doctoral de la autora y su subsiguiente experiencia en el ámbito de la Práctica Reflexiva, se presenta el estudio investigativo enmarcado en el Practicum de estudiantes de Grado de Educación Infantil y Primaria de la Facultad de Educación de la Universitat Internacional de Catalunya, (UIC), con el objetivo de destacar la importancia de una práctica reflexiva y la formación de maestros reflexivos a fin de llevar una mejor gestión del aula y facilitar la resolución de los problemas que se van presentando por medio de un análisis en el que se integra la teoría con la práctica.La investigación inició con su correspondiente contextualización y la creación de una propuesta del Método R5 de Práctica Reflexiva, el cual fue aplicado y valorado por los estudiantes del Practicum bajo la supervisión de sus maestros-tutores, lo que permitió recoger y analizar datos bajo los rubros de Formación Reflexiva, Articulación de Teoría y Práctica, Método R5 y Uso de Portafolio. Los resultados fueron favorables mostrando que la Práctica Reflexiva a través del Método R5 y los demás elementos mencionados, contribuyen al desarrollo de la capacidad reflexiva de quienes los aplican mejorando su profesionalización docente.
Interval-type theorems concerning means
Authors: Pasteczka Paweł 
Published: June 2018

Abstract
Each family ℳ of means has a natural, partial order (point-wise order), that is M ≤ N iff M(x) ≤ N(x) for all admissible x.
In this setting we can introduce the notion of interval-type set (a subset ℐ ⊂ℳ such that whenever M ≤ P ≤ N for some M, N ∈ℐ and P ∈ℳ then P ∈ℐ). For example, in the case of power means there exists a natural isomorphism between interval-type sets and intervals contained in real numbers. Nevertheless there appear a number of interesting objects for a families which cannot be linearly ordered.
In the present paper we consider this property for Gini means and Hardy means. Moreover, some results concerning L
∞ metric among (abstract) means will be obtained.
Direct Contact Membrane Distillation for Separation of Hcl From A Mixture of Acids
Authors: Hassan Assrar Abdullah , Adel Jabbar Hala 
Published: June 2018

HCl is separated from HCl –H2SO4 solution by membrane distillation process(MD). The flat –sheet membranes made from polyvinylidene fluoride (PVDF) and polypropylene (pp.). Plate and frame these types of membrane where used in the process. The feed is a mixture of HCl and H2SO4 acids compositions depended on metals treated object.HCl concentration increased in the permeate during the process but sulfuric acid increased gradually in the feed .During the concentration of solution acids concentrations in the feed at the beginning were 50 g/dm3 of sulfuric acid and 50 g/dm3 of hydrochloric acid at 333K feed temperature the permeate flux was 71 dm3/m2.d. At a higher concentration of HCl in the feed 111g /dm3 and 61 g/ dm3 of sulfuric acid at the feed temperature 333K volume permeate flux was 57 dm3/ m2.d . At a higher concentration of sulfuric acid in the feed 161 g/dm3 and 60 g/dm3 of HCl decrease the permeate flux from 71 to 35 dm3/m2.d at 333K . The permeate flux increase from 35 at 333K to 85 at 343 K increase the temperature caused an increase in permeate flux. Increases in sulfuric acid concentration from 50 to 161 g/dm3 decrease the volume permeate flux from 71 to 35 dm3 /m2.d, HCl concentration was achieved a higher value 9.1 g/dm3 during the process at the feed concentration 161g/dm3 of sulfuric acid and 60g/dm3 of hydrochloric acid at feed temperature 343K.
FEATURES OF THE MICROBIAL SPECTRUM UROGENITAL SYSTEM OF WOMEN WITH RECURRENT PYELONEPHRITIS
Authors: Romanenko O. , Stepanova N. , Rudenko A. , Kruglikov V. , Lebid L. , Kolesnyk M. 
Published: June 2018

The aim of our research was to identify the peculiarities of the microbial spectrum urogenital system of the women with recurrent pyelonephritis.
Materials and methods. We have conducted a comprehensive micro-biological examination different biological material (urine, vaginal swabs, scraping of urethral and cervical canal’s) of 175 women with recurrent pyelonephritis. The patients were divided in accordance with frequency of recurrent. The microbial spectrum urogenital system of 98 women with recurrent pyelonephritis (group 1) was compared with 77 women with sporadic pyelonephritis (up to 2 times per year) (group 2). The research included the process of identification of bacterial agents, mollicutes, chlamydia as well as yeasts.
Results. In the women with recurrent pyelonephritis had the significant increase of frequency of identification of E. faecalis in urine (p=0.03), in urethral canal (p=0.05), and vaginal scraping (p=0.02). 48 women from 1st group had bacterial mix-infection. At the same time, the women from comparative group had only in 25 (32.6%) cases (p=0.027). The direct associative relationship was found between existence of S. epidermidis in urethral canal, in cervical canal, in vagina and the frequency of recurrent pyelonephritis (ρ=0.2, р=0.009; ρ=0.23, р=0.004 and ρ=0.19, р=0.01 respectively); E. faecalis in the urethral canal (ρ=0.19, р=0.02); Candida albicans in the vagina (ρ=0.17, р=0.03). 79.6% examined patients were infected by mollicutes, viruses and chlamydia.
Conclusions. Consistent high level of urethral’s and vaginal’s bacterial weight of the women with recurrent pyelonephritis leads to the migration of causative agents into bladder and to activates formation of recurrent of the disease. Identified peculiarities of microbial spectrum prove the necessity mandatory micro-biological research not only urine, but urethra, cervical canal, and vagina.
EXPRESSION OF INTERCELLULAR ADHESION MOLECULE (ICAM-1) ON LYMPHOCYTES AND THE LEVELS OF PRO- AND ANTIINFLAMMATORY CYTOKINES IN PATIENTS WITH PYELONEPHRITIS
Authors: Gaysenyuk F.Z. 
Published: June 2018

The aim of this work is to investigate the level of mononuclear cells, expressing intercellular adhesion molecule (CD54+), pro- (IL-1, TNF-a) and antiinflammatory (IL-4, TGF-в) blood cytokines in the patients with pyelonephritis PN, to determine the peculiarities in acute and chronic its course.
Materials and methods. The immuno-enzymic method ELISA and the corresponding test-systems (“Diaclone”, “DRG”) were used to study the levels of blood cytokines and immuno-fluorescent with “Coltage” (USA) – the level of CD54+-cells.
Results. It has been demonstrated that CD54+-lymphocytes, IL-1, TNF-a, IL-4 and TGF-ft in blood were increased in patients with acute and chronic pyelonephritis, compared with healthies. The number of lymphocytes expressing CD54 and the level of TGF-ft were higher in patients with chronic pyelonephritis.
Conclusion. The high level of cytokines and CD54+-lymphocytes in blood ofpatients confirm their important role in immunogenesis of pyelonephritis, the interrelation is especially interesting between CD54+-cells and TGF-ft in chronic process.
FEATURES TOPICAL DIAGNOSIS OF CHRONIC INFLAMMATORY DISEASES OF THE PELVIC ORGANS CAUSED ÇHLAMYDTA TRACHOMATIS
Authors: Shcherbak M.O. 
Published: June 2018

To analyze the information content of the topical diagnostic C.trachomatis in a comparative perspective in view of possible lesions.
Materials and methods: In this paper the results ofan assessment of topical diagnosis in 142 women with Chlamydia infection HPID from different parts of the fence biomaterial (cervix, urethra, tonsils, colon, and conjunctiva of the eye) by PCR.
Results: The majority of women with HPID - C.trachomatis postulation were the study of the biological material by PCR from the cervices, at 62.0% of the urethra, at 38.7% of the rectum, at 37.3 from the tonsils 17.6 and % of the conjunctiva of the eye.
Conclusions: conducting clinical and microbiological analysis of Chlamydia infection HPID allowing for the topical diagnosis revealed informative clinical extended analysis of the study pathology.
SPECIFIC INFLAMMATORY PROTEINS IN THE BLOOD AND URINE OF PATIENTS WITH RECURRENT PYELONEPHRITIS
Authors: Korol L. , Stepanova N. , Migal L. 
Published: June 2018

The aim of our study was to investigate the content of specific inflammatory proteins (C-reactive protein, fibronectin, cystatin C) in the blood and urine ofpatients with pyelonephritis, depending on the frequency of recurrences.
Patients and methods. A cross-sectional study was carried out and included 64 female patients with uncomplicated pyelonephritis, over 18 years (mean 32.3 ± 9 years). We determined C-reactive protein (CRP), fibronectin (FN), and cystatin C CysC) in the blood and urine of patients using test kits «Dialab» (Austria) by immunoturbidimetric method. After the examination patients were divided into II groups: I (n = 34) – women with recurrent pyelonephritis and II (n = 30) – patients with sporadic pyelonephritis (up to 2 times per year).
Results. The patients of group I showed the highest level of blood concentrations of CysC (p = 0.02) and a decrease of FN (p = 0.01). We found an inverse correlation between the number of recurrences of pyelonephritis per year and the blood level of FN (r = -0.42, p = 0.007). In addition, we determined a strong direct correlation between the urinary FN and blood level of CysC (r = 0.6, p <0.0001).
Conclusions. Decrease of FN and growth of CysC in the blood ofpatients with recurrent pyelonephritis is the result offrequent inflammatory activity. Determination of specific inflammatory proteins in the blood and urine ofpatients with pyelonephritis can be used as alternative markers for diagnosis and monitoring of disease
INFLUENCE OF ANGIOTENSIN-CONVERTING ENZYME RAMIPRIL ON INDICATORS OF TUBULO- INTERSTITIAL RENAL DAMAGE IN PATIENTS WITH CKDI-II: GLOMERULONEPHRITIS
Authors: Dolinnayä M.A. , Shekhovtseva T.G. 
Published: June 2018

The aim: to examine the relations between morphological tubulointerstitial (TIT) parameters of kidney damage and neutrophil gelatinase-associated lipocalin (NGAL) and interleukin-18 (IL-18) of blood serum in patients with chronic glomerulonephritis (CGN) with saved renal function, and to estimate the therapeutic correction of identified changes using ACE inhibitor ramipril..
Materials and methods. The study included 81 patients with CGN. Patients were divided into 2 clinical groups: CGN patients with arterial hypertension (AH), CGN without AH. The average daily dose of ramipril in patients with AH was 12,8 ± 5,6 mg, in patients without hypertension – 2,5 mg.
We used kidney biopsy data for the analysis of renal damage on the following parameters: dystrophic and necrotic changes in tubular epithelium, thickening and/or cleavage of tubular basement membrane, presence ofcellular infiltration, interstitial fibrosis (IF). The level of NGAL and IL-18 in serum were determined by ELISA.
Results. We statistically confirmed a direct link between blood NGAL and IF (r=+0,65;p<0,05), blood IL-18 and dystrophic changes in tubular epithelium (r=+0,81;p<0,05). It was established that the kidney IF diagnostic using NGAL determination in serum is highly sensitive and specific, with an efficiency of 95,3 %, and dystrophic changes in tubular epithelium via serum IL-18 – 96,6 %.
Conclusion: serum levels of NGAL and IL-18 are sensitive markers of kidney TIT damage in patients with CGN with diagnostic efficiency up to 97 %. Under the influence of 24 weeks treatment with an ACE inhibitor ramipril we observed a significant decrease in levels of markers of kidney TIT damage, that confirmed nephroprotective effect of the drug.
ASSOCIATION OF HLA AND PROINFLAMMATORY CYTOKINES OF BLOOD IN PATIENTS WITH GLOMERULONEPHRITIS
Authors: Kolesnyk M. , Driyanska V. , Velychko M. , Drannik G. , Petrina O. 
Published: June 2018

Introduction. Cytokines and HLA are of important part of immunogenesis of many diseases, therefore the analysis of these indices and this associations in dependence of glomerulonephritis (GN) can define their value as the additional prognostic markers.
Aim of the work is to determine the peculiarities of associations the high serum levels ofproinflammatory cytokines (TNF a, MCP-1, IL-18) and some HLA in phenotype to substantiate of chronic glomerulonephritis with nephrotic syndrome (CGN, NS) immunogenesis and to ascertain the additional prognostic markers.
Materials and methods. There was studied the HLA-antigens distribution in the 264 CGN, NS adult patients and 350 healthy donors by typing the lymphocytes with the aid of standard microlymphocytotoxic test (Terasaki’s test). Using IFA, the level of the proinflammatory cytokines was studied in the blood serum - MCP-1 in 39, IL-18 – 40 and TNF-a - 96patients.
Results. HLA-A23, -24, -B8, -38, -41, -44, DR1, -4, -w52 in adults patients have associations (RR>2) CGN, NS; the attributive risk (a>0,1) to develop GN detected in patients have A24, B8, DR 1, 4, w52. The relative risk (RR) to develop chronic renal failure (CRF) is in detection of HLA-10, -29, -30, -41, -51, DR4; attributive risk (AR) - A10.
The CGN, NS patients showed statistically higher level of the serum proinflammatory cytokines – TNF-6, IL-17, MCP-1 with more high indices of the TNF-a in patients with HLA-A23, -A28, -B44 (RR of CGN, NS), -A10 (AR of CRF), IL-18 - A24 (AR of CGN, NS) ma A10 (AR of CRF). The highest levels of MCP-1 detected in adults case have risk antigens - relative B41, attributive - A28, B8, and predictor of CRF B41, wich may be negative marker for prognosis.
Conclusion. It was to determine associations the serum levels of some cytokines and HLA in patients with CGN, NS. We think it appropriate to study HLA and proinflammatory cytokines TNF-a, IL-18 and MCP-1 in blood as additional negative prognostic predictors for the differentiating approach to treatment.
PECULIARITIES OF IMMUNITY IN PATIENTS WITH DIABETES MELLITUS AND CHRONIC PYELONEPHRITIS
Authors: Busygina Yu. , Driyanska V. , Stepanova N. , Gaysenyuk F. , Lebed L. , Lavrenchuk O. , Kolesnyк M. 
Published: June 2018

The pro- and antiinflammatory cytokines participate in antiinfective immunity, that is why it is necessary study their peculiarities in determination of the role in the immunopathogenesis of pyelonephritis, including complications of diabetes mellitus (DM).
The purpose of the work is to study the immune status and levels of pro- and antiinflammatory blood cytokines in the patients with chronic pyelonephritis (CPN), to determine the peculiarities in cases of DM.
Materials and methods. The immuno-enzymic method ELISA and the corresponding test-systems were used to study the levels of cytokines in blood and also standard immunity indices.
Results. The analysis showed the significant increase in levels of all studied pro- (TNF-б, MCP-1, IL-17, -23) and antiinflammatory (IL-4, TGF-в) cytokines in all patients with CPN and in every group – with (2) and without DM (3). In 3 gr. (CPN+DM) the CD4+/CD8+ are significantly lower, while in IgM, МСР-1 and TNF-б levels – higher than in the 1 gr. (DM without CPN), and IL-4 , NGAL – than in 2 gr. (CPN without DM).
Conclusion. The high level of cytokines (TNF-б, MCP-1 and IL-23) in blood confirms their important role in CPN+DM and CPN without DM. In patients with CPN+DM marked reduction in regulatory index (CD4+/CD8+) and higher levels of proinflammatory cytokines (TNF-б, MCP-1). Our investigation showed that NGAL level in serum was increased more significantly in 3 gr.; this fact may confirm that renal disfunction was more severe in patients with CPN+DM.
ANTIBIOTIC- ASSOCIATED RISK THE REDUCTION OF LACTOBACILLUS SPP. IN THE INTESTINAL MICROBIOTA IN PATIENTS WITH URINARY TRACT INFECTIONS
Authors: Stepanova N. , Stashevska N. , Lebid L. , Savchenko S. , Kolesnyk M. 
Published: June 2018

The aim of our study was to evaluate a risk reduction of indigenous gut microbiota in patients with urinary tract infection (UTI, associated with the intake of antibacterial medicinal products
Materials and methods. To this retrospective cohort case-control study were involved 233 women with UTI. The mean age in the patient population was 36.7 ± 15.6 years. Cases were defined as reducing the number of Lactobacillus spp. < 10 million colony forming units in 1 g offeces (mln. CFU/g). We evaluated the daily urinary oxalate excretion and bacteriological seeding feces. Investigational antibiotics were medicines which are generally used to treat the outpatient with UTI.
Results. The data analysis demonstrated an extremely high risk the reducing of Lactobacillus spp. colonization in the patient’s intestine. The use of ciprofloxacin was significantly associated with an availability of hyperoxaluria ( = 0.31,
p = 0.008).
Conclusions. Thus, the use of antibacterial medicinal products, even in prophylactic doses, by the patients with UTI leads to the destruction of the normal composition of gut microbiota, and, primarily, due to the fact that the content of Lactobacillus spp. is deceased.
QUALITY OF LIFE OF HEMODIALYSIS PATIENTS WITH ARTERIOVENOUS FISTULA
Authors: Rusyno I. , Tsiupiaka O. 
Published: June 2018

Objective: to study the basic quality of life in patients with chronic kidney disease and their relationship, with different numbers formed arteriovenous fistula.
Materials and methods. Interviewed 56patients, who are treated with chronic hemodialysis department. To study the quality of life used (KDQOL-SF ™). Also used a questionnaire that enables presence fistula determine the impact on quality of life of patients.
Results. Using statistical method cluster analysis, made differentiation studied three groups - clusters, which differ in different levels of the indicators of QOL, namely «Patients middle-manifestation of physical and psychological indicators of QOL» – 40%, «Patients with low the manifestation of physical and psychological QOL parameters «- 25% of subjects, and» Patients with high level of physical and psychological manifestations of QOL performance «- 35% sample of of the patients.
Based on statistical comparative analysis revealed differences between the estimated quality of life in men and women. Role functioning due to physical condition in women is slightly lowered than men. In women, there is a greater level of pain than men. Men overall higher rate their health than women. Men are characterized by a higher level of social functioning than women.
Conclusions. Patients with chronic hemodialysis age have difficulties in physical functioning and performance of daily affairs. Mental health by increasing the biological age becomes stronger and fitter.
His attitude to the presence of fistula in upper limb showing men and women equally, that they feel discomfort and limitations in performing daily routine. The more surgeries performed to form vascular access in patients, the occurrence characteristically uncomfortable sensations in all aspects of life
URINARY SYSTEM PATHOLOGY IN CHILDREN POPULATION OF KHARKIV REGION: MORBIDITY AND SOME RISK FACTORS
Authors: Muratov G. R. , Kolibaeva T. F. , Sorokina I. V. , Myroshnychenko M. S. 
Published: June 2018

Urinary system pathology in children now is one of the most important problems of medical science.
The aim of this study – to analyze the morbidity and reveal the risk factors for development of urinary system diseases in children of Kharkiv region.
Materials and methods. The material of the study was the information (gender, age, weight and body length at birth, gestational age, clinical diagnosis), obtained during hospitalization of 663 patients aged from 3 months to 17 years in the nephrological center of Kharkiv regional children clinical hospital during the period from 2012 to 2013 years.
Results. The authors found that in children population of Kharkiv region among all diseases of urinary system a significant number of cases occur in congenital malformations, dismetabolic nephropathy, urolithiasis.
Conclusions. Regional risk factors for development of urinary system pathology in children are female and living in the village. Decreased weight and body length at birth are risk factors for development in children urinary system congenital malformations.
COLON OXALATE-DEGRADING BACTERIA COLONIZATION IN PATIENTS WITH RECURRENT PYELONEPHRITIS AND ITS RELATIONSHIP WITH ADMINISTRATION OF ANTIBIOTICS (PILOT STUDY)
Authors: Dzyubenko N. , Stashevska N. , Tolstanova G. , Sergiychuk T. , Akulenko I. , Stepanova N. 
Published: June 2018

Antibiotic therapy and long-term antibiotic prophylaxis affect the normal flora of the gastrointestinal tract in the patients with recurrent pyelonephritis. It may disturb the balance in oxalate-degrading bacteria in colon and induce hyperoxaluria.
The aim of this study was to investigate the level of colon oxalate-degrading bacteria colonization inpatients with recurrentpyelonephritis and its association with administration ofantibiotics.
Patients and methods. The pilot observational cross-sectional study, involving 12 patients with uncomplicated recurrent pyelonephritis, non-stone formers. Oxalate-degrading bacteria in feces were identified by bacteriological culture method in the sodium oxalate reach medium.
Results. Oxalate-degrading bacteria were detected in feces of 6 (50%) surveyed patients. The number of oxalatedegrading bacteria ranged from 2,0 to 7,0 lg CFU/g in feces and depended on the time after the last administration of antibiotics (F = 4,6; P = 0.05). The levels of oxalate-degrading bacteria colonization and urinary oxalate excretion in surveyed women had a moderate inverse correlation (p =-0,6;P = 0.03).
Conclusions. The significantly higher urinary oxalate excretion in women non stone-formers with recurrent pyelonephritis may be associated with the application of antibiotics and a subsequent decolonization of oxalate-degrading bfcteria: must befurther confirmed in ranaomizea study.