bluuebunny/crossref_metadata_2025_split huggingface dataset:
Event-Related Potentials Reveal Evidence for Late Integration of Emotional Prosody and Facial Expression in Dynamic Stimuli: An ERP Study
Authors: Föcker Julia , Röder Brigitte 
Published: May 2019

Abstract
The aim of the present study was to test whether multisensory interactions of emotional signals are modulated by intermodal attention and emotional valence. Faces, voices and bimodal emotionally congruent or incongruent face–voice pairs were randomly presented. The EEG was recorded while participants were instructed to detect sad emotional expressions in either faces or voices while ignoring all stimuli with another emotional expression and sad stimuli of the task irrelevant modality. Participants processed congruent sad face–voice pairs more efficiently than sad stimuli paired with an incongruent emotion and performance was higher in congruent bimodal compared to unimodal trials, irrespective of which modality was task-relevant. Event-related potentials (ERPs) to congruent emotional face–voice pairs started to differ from ERPs to incongruent emotional face–voice pairs at 180 ms after stimulus onset: Irrespectively of which modality was task-relevant, ERPs revealed a more pronounced positivity (180 ms post-stimulus) to emotionally congruent trials compared to emotionally incongruent trials if the angry emotion was presented in the attended modality. A larger negativity to incongruent compared to congruent trials was observed in the time range of 400–550 ms (N400) for all emotions (happy, neutral, angry), irrespectively of whether faces or voices were task relevant. These results suggest an automatic interaction of emotion related information.
A 3-Dimensional Model of the Human Round Window Membrane
Authors: Nomura Yasuya , Tanaka Toru , Kobayashi Hitome , Kimura Yurika , Soejima Yurie , Sawabe Motoji 
Published: May 2019

Objectives: The round window membrane (RWM) is small in size, making it difficult to clarify its shape and structure. The authors examined a 40x magnified 3-dimensional model of the human RWM to clarify its morphologic aspects and characteristics. Methods: An RWM specimen was obtained from an archival, formalin-fixed, decalcified, left temporal bone of an 84-year-old female cadaver. The data obtained by laser scanning microscopy were input into a 3-dimensional printer. After a model of the RWM was created, the following features were examined: striae on the surfaces, curvatures, thickness, and areas. Cross sections of the original specimen were made for histological observations. Results: The contour of this RWM model was approximately elliptic, with a saddle shape. When illuminated from the scala tympani side, the surface facing the fossula exhibited dark anterior and clear posterior portions. A borderline appeared where the 2 portions were bound along the short axis of the ellipse. This borderline was identified as the line of inflection. Collagen fibers were shown to run parallel to the borderline in the posterior portion but were fanned out in the anterior portion. Conclusions: The magnified 3-dimensional model clarified gross anatomy and characteristics of the RWM. It is good teaching material for small tissues, such as the RWM.
A Spatially Explicit Capture–Recapture Model for Partially Identified Individuals When Trap Detection Rate Is Less than One
Authors: Dey Soumen , Delampady Mohan , Karanth K. Ullas , Gopalaswamy Arjun M. 
Published: May 2019

Spatially explicit capture–recapture (SECR) models have gained enormous popularity to solve abundance estimation problems in ecology. In this study, we develop a novel Bayesian SECR model that disentangles two processes: one is the process of animal arrival within a detection region, and the other is the process of recording this arrival by a given set of detectors. We integrate this complexity into an advanced version of a recent SECR model involving partially identified individuals (Royle JA. Spatial capture-recapture with partial identity. arXiv preprint arXiv:1503.06873, 2015). We assess the performance of our model over a range of realistic simulation scenarios and demonstrate that estimates of population size N improve when we utilize the proposed model relative to the model that does not explicitly estimate trap detection probability (Royle JA. Spatial capture-recapture with partial identity. arXiv preprint arXiv:1503.06873, 2015). We confront and investigate the proposed model with a spatial capture–recapture dataset from a camera trapping survey of tigers (Panthera tigris) in Nagarahole study area of southern India. Detection probability is estimated at 0.489 (with 95% credible interval (CI) [0.430, 0.543]) which implies that the camera traps are performing imperfectly and thus justifying the use of our model in real world applications. We discuss possible extensions, future work and relevance of our model to other statistical applications beyond ecology. AMS classification codes: 62F15, 92D40
Occupational Life in the Home Environment: The Experiences of People with Disabilities
Authors: Lund Maria Larsson , Nygård Louise 
Published: May 2019

Background There is a need to empirically explore the occupational engagement of people with disabilities to support the development of occupational therapy interventions. Purpose This study describes how people with disabilities experience their occupational lives in their home environment. Method Thirteen people with physical disabilities living at home were interviewed and data were subsequently analysed using a constant comparative method. Results The findings showed that interactions between the individuals and their environment influenced their experiences of engaging in occupations and the meaning of their home. Occupations formed three categories: always performed with others, occasionally disrupted or deprived. These were particularly related to the social support that was provided under different conditions. This condition formed a central category: access to social support for occupations. Their experiences of performing occupations in the home also formed another central category: transformed meaning of the home. Practice Implications By understanding enabling conditions as well as barriers to occupational engagement, effective occupational therapy interventions can be developed to support the occupational lives of people with disabilities.
Heart Age, Cardiovascular Disease Risk, and Disparities by Sex and Race/Ethnicity Among New York City Adults
Authors: Tabaei Bahman P. , Chamany Shadi , Perlman Sharon , Thorpe Lorna , Bartley Katherine , Wu Winfred Y. 
Published: May 2019

Objectives: Cardiovascular disease (CVD) is the leading cause of mortality in the United States. The risk for developing CVD is usually calculated and communicated to patients as a percentage. The calculation of heart age—defined as the predicted age of a person’s vascular system based on the person’s CVD risk factor profile—is an alternative method for expressing CVD risk. We estimated heart age among adults aged 30-74 in New York City and examined disparities in excess heart age by race/ethnicity and sex. Methods: We applied data from the 2011, 2013, and 2015 New York State Behavioral Risk Factor Surveillance System to the non–laboratory-based Framingham risk score functions to calculate 10-year CVD risk and heart age by sex, race/ethnicity, and selected sociodemographic groups and risk factors. Results: Of 6117 men and women in the study sample, the average heart age was 5.7 years higher than the chronological age, and 2631 (43%) adults had a predicted heart age ≥5 years older than their chronological age. Mean excess heart age increased with age (from 0.7 year among adults aged 30-39 to 11.2 years among adults aged 60-74) and body mass index (from 1.1 year among adults with normal weight to 11.8 years among adults with obesity). Non-Latino white women had the lowest mean excess heart age (2.3 years), and non-Latino black men and women had the highest excess heart age (8.4 years). Conclusions: Racial/ethnic and sex disparities in CVD risk persist among adults in New York City. Use of heart age at the population level can support public awareness and inform targeted programs and interventions for population subgroups most at risk for CVD.
A Cluster of Acoustic Neuromas in Fish Hatchery Workers
Authors: Page Elena H. 
Published: May 2019

The National Institute for Occupational Safety and Health (NIOSH) received a request from the United States Fish and Wildlife Service (FWS) to determine if there is a relationship between acoustic neuroma and fish hatchery work. The request was triggered by a report from an FWS employee who suspected the possibility of such an association. Investigators used data provided by the personnel office of the FWS to calculate the incidence of acoustic neuroma among fish hatchery workers, and then to compare it with national rates. Four confirmed cases of acoustic neuroma were found among former fish hatchery workers. The overall incidence was estimated to be 15.41 per 100,000 person-years. This rate is more than 15 times higher than the rate among the general population. Even so, the small number of cases, as well as other factors, preclude the NIOSH from concluding that there is a definite cause-and-effect relationship. Further study is warranted.
Acanthamoeba Sinusitis with Subsequent Dissemination in an AIDS Patient
Authors: Kim Sam Y. , Syms Mark J. , Holtel Michael R. , Nauschuetz Karen K. 
Published: May 2019

Otolaryngologists can play an important role in the care of patients with acquired immunodeficiency syndrome (AIDS) and/or human immunodeficiency virus infection. We present the case of an AIDS patient who was hospitalized for dehydration and who was soon found to have sinusitis and subsequent disseminated infection caused by Acanthamoeba. To treat the Acanthamoeba infection, the patient was started on oral itraconazole and intravenous metronidazole; IV pentamidine was added 2 days later. Despite aggressive therapy, on the eleventh day of hospitalization, the patient was obtundent and provided minimal response to noxious stimuli. He died on the sixteenth day of hospitalization. This case is one of only six reported cases of Acanthamoeba associated with sinusitis. Current therapeutic regimens have not been successful for most of these patients, and the prognosis is poor.
Spondyloepiphyseal Dysplasia Congenita Associated with Conductive Hearing Loss
Authors: Dahiya Ravinder , Cleveland Sandra , Megerian Cliff A. 
Published: May 2019

Spondyloepiphyseal dysplasia is a disorder characterized by abnormalities of growth. Previous studies of this disorder have identified a significant incidence of associated hearing loss. Hearing loss has been reported to occur in 25 to 30% of affected patients. To date, all reports of associated hearing loss have indicated the presence of a sensorineural component. In this article, we report the case of a child who was diagnosed with spondyloepiphyseal dysplasia congenita and who was found to have a significant conductive hearing loss with a Carhart's notch, indicating the likely presence of stapes footplate fixation. We also review the diagnosis of this condition and the literature associated with hearing loss as it occurs with this disorder.
Facial Paralysis caused by Malignant Skull Base Neoplasms
Authors: Marzo Sam J. , Leonetti John P. , Petruzzelli Guy 
Published: May 2019

This article has been published previously in Neurosurgical Focus: Marzo SJ, Leonetti JP, Petruzzelli G. Facial paralysis caused by malignant skull base neoplasms. Neurosurgical Focus 2002, Article 2;12(5) ( http://www.neurosurgery.org/focus/may02/12-5-nsf-toc . html). Object Bell palsy remains the most common cause of facial paralysis. Unfortunately, this term is often erroneously applied to all cases of facial paralysis. Methods The authors performed a retrospective review of data obtained in 11 patients who were treated at a university-based referral practice between July 1988 and September 2001 and who presented with acute facial nerve paralysis mimicking Bell palsy. All patients were subsequently found to harbor an occult skull base neoplasm. A delay in diagnosis was demonstrated in all cases. Seven patients died of their disease, and four patients are currently free of disease. Conclusions Although Bell palsy remains the most common cause of peripheral facial nerve paralysis, patients in whom neoplasms invade the facial nerve may present with acute paralysis mimicking Bell palsy that fails to resolve. Delays in diagnosis and treatment in such cases may result in increased rates of mortality and morbidity.
Staging in Cholesteatoma Surgery
Authors: Deguine Christian 
Published: May 2019

The closed technique is the treatment of choice for middle ear cholesteatoma in the opinion of the author. Several interventions may be required. At the onset, the purpose of the systematic second stage procedure was to verify the absence of any residual cholesteatoma. Experience has shown that the interest of this second intervention lies equally in the opportunity to observe the evolution of the otitis disease process, and the tubal status and in the possibility of restoring transmission under optimal conditions, thanks in particular to the utilization of thick silastic sheeting. This technique necessitates, however, a long-term follow-up. On occasion, a third intervention may be required. Despite the iterative nature of this surgery, it should be considered as a form of a logical progression offering the best chances of a successful anatomic and functional outcome for the patient.
Electrocautery versus Epinephrine-Injection Tonsillectomy
Authors: Trent Christopher S. 
Published: May 2019

This prospective, single-blinded study on tonsillectomy was done to compare the Bovie electrocautery dissection technique with the epinephrine-and-lidocaine injection technique and to document which technique is safer, faster, and less morbid. Twenty-nine patients who were scheduled for tonsillectomy at two Northern California Region Kaiser Permanente Medical Centers were enrolled in the study. Each patient served as his or her own control, and tonsillectomy technique was randomized on the basis of even or odd numbers of the last digit of the medical record number. The time of injection of epinephrine and time of dissection for each tonsil was recorded. Blood loss was quantified for each dissection, and pain was assessed by asking the patient which side hurt more. I found no statistically significant difference in operating time, intraoperative blood loss, or postoperative hemorrhage between these two methods. The electrocautery, or Bovie, technique produced more clinically significant eschar and delayed healing than the epinephrine-injection technique did. The Bovie technique produced more inadvertent burns to surrounding tissue than the epinephrine-injection technique did, but the epinephrine caused transient tachycardia in 14% of the study participants. The present study showed no difference between the two techniques in postoperative pain experienced by study participants, but other recent studies have shown that patients experience more pain when the Bovie technique is used. Study data do not support the superiority of Bovie tonsillectomy. I recommend epinephrine-injection tonsillectomy as a safe and expedient operation.
Undifferentiated Carcinoma of the Nose and Paranasal Sinuses
Authors: Gallo Oreste , Graziani Paola , Fini-Storchi Omero 
Published: May 2019

Among twenty-six “undifferentiated” tumors of the nasal cavity and paranasal sinuses treated from 1970 to 1990 at the Institute of Otolaryngology of Florence University, 13 were ultimately diagnosed as true undifferentiated sinusonasal carcinoma (SNUC) by conventional light microscopy and use of monoclonal antibodies to epithelial membrane antigen and cytokeratins. SNUC patients, who ranged in age from 20 to 82 years, often had multiple sinonasal symptoms due to very large tumors (nine of 13 tumors were staged as T3–T4) with short average delay of 4 months between onset of symptoms and diagnosis. Both data suggest the high growth capacity and aggressiveness of such a tumor. In our series, follow-up evidenced an overall crude 5-year survival rate of 15.5%. Worse prognostic factors are neck metastases and orbital invasion, according to the behavior of more common carcinomas of the nose and paranasal sinuses. We also found a better prognosis for SNUC primarily arisen in the nasal cavity than in paranasal sinuses (crude 5-year survival rate of 66% vs. 10%, respectively). The histopathological and clinical analysis of our series shows that SNUC is a highly aggressive, uncommon tumor of the nose paranasal sinuses, which should be recognized in advance for a more aggressive treatment by combined multiple therapy.
Fatal Mediastinal Abscess from Upper Respiratory Infection
Authors: Isaacs Larry M. , Kotton Bernard , Peralta Modesto M. , Shekar Raja , Meden Glenn , Brown Leon A. , Raaf John H. 
Published: May 2019

Suppurative mediastinitis following neck infection is an uncommon entity that carries a 40% mortality. It is most commonly associated with esophageal perforation or odontogenic abscess. The rapidity of spread has been attributed to dependent drainage from the neck into the mediastinum, negative intrathoracic pressure, and synergistic necrotizing bacterial growth. Cultures obtained usually grow streptococci and/or Bacteroides. We report the case of a 34-year-old woman with an upper respiratory infection who subsequently was found to have a para-/retropharyngeal and mediastinal abscess. Septic shock, respiratory failure, and death ensued, despite aggressive treatment with broad-spectrum antibiotics (for both aerobes and anaerobes), surgical drainage of the neck and mediastinum, and cardiorespiratory support. The danger of a rapid downhill clinical course with mortality due to suppurative mediastinitis makes early diagnosis of critical importance. All clinicians evaluating a “sore throat” should consider neck edema or gas on neck radiograms as evidence of cervical abscess, and subsequent widening of the mediastinum on chest x-ray as an ominous sign suggesting mediastinal abscess.
The Enlarged Vestibular Aqueduct Syndrome (EVA Syndrome)
Authors: Belenky Walter M. , Madgy David N. , Leider Jeffrey S. , Becker Christie J. , Hotaling Andrew J. 
Published: May 2019

The presentation to the Department of Pediatric Otolaryngology at the Children's Hospital of Michigan of a series of patients with sensorineural hearing loss and enlargement of the vestibular aqueduct prompted exploratory tympanotomy in three patients (two unilateral and one bilateral), for a total of four ears. These explorations were prompted by progression and/or fluctuation of hearing levels. The discovery of abnormal round windows in all four ears with a post-traumatic fistula present in one ear suggested the presence of a new association. A previously undescribed association of an enlarged vestibular aqueduct, sensorineural hearing loss and round window abnormality with potential fistula formation was identified. A review of the anatomy and physiology, literature review, and a prospective analysis with discussion of eight patients with enlarged vestibular aqueduct syndrome evaluated and treated at Children's Hospital of Michigan, is presented. We conclude that all children with sensorineural hearing loss should undergo extensive evaluation to determine etiology, including radiographic studies of the temporal bone. Further, the presence of an enlarged vestibular aqueduct should prompt the otolaryngologist to consider the presence of a round window abnormality and the potential for predisposition to perilymph fistula.
Implantation of Electromagnetic Ossicular Replacement Device
Authors: Tos Mirko , Salomon Gerhard , Bonding Per 
Published: May 2019

Semi-implantable hearing aids consisting of permanent middle ear implanted magnet, either partial ossicular replacement prostheses (PORP's) or total ossicular replacement prostheses (TORP's) driven by an electromagnet placed in the ear canal have been tested on six patients undergoing surgery for chronic otitis. The surgical and audiological problems are described. The audiological results were excellent in all six cases. A functional gain of 40-70 dB can be obtained for entire frequency range of the audiogram.
Exploring the Maze of Adverse Reactions to Foods
Authors: King Hueston C. 
Published: May 2019

Nowhere in medicine is a test or battery of tests more needed than in the diagnosis of adverse reactions to foods. Such tests are not at present a reality. Research produces tests that individually appear to show validity, but when challenged with the entire range ofpossible adverse reactions and their results, the tests fall short. Considering the range of mechanisms involved in adverse reactions to foods, this is to be expected. There is a tendency to discount positive test results when they fail to cover all of the parameters desired. The inherent weakness in any test is that all available formats explore a single or limited reaction route. The reality is the presence of multiple routes, multiple target organ s, and multiple external variable s not subject to programming into a single test. Considering the range of possibil ities, it is amazing that any existing tests show any clinical validity at all. We as scientists should not denigrate any study that shows a significant degree of reliability, even within a limited range. This simply halts progress. An encouraging study should be used as a stepping stone to a more comprehensive format for evaluating the overall range of adverse reactions and providing us with at least some inroads in coping with this most difficult problem. To quote Sir Peter Medawer on receiving the Nobel Prize in Science: “Nothing must be said or written that diminishes the likelihood that someone else will get at the truth.”
The Management of Sinusitis in Patients Infected with the Human Immunodeficiency Virus (HIV)
Authors: Tami Thomas A. 
Published: May 2019

As the Human Immunodeficiency Virus (HIV) has extended its influence across the United States, otolaryngologists have been increasingly called upon to manage its various head and neck manifestations. Sinusitis is a very prevalent, yet difficult, management problem in this patient population. The pathophysiology of sinusitis in this setting relates to altered helper T-lymphocyte function, an abnormal inflammatory response as well as increased IgE-mediated inflammation. Chronic HIV-related sinusitis is often due to Pseudomonas aeruginosa, Staphylococcus aureus, or anaerobic bacteria, and empiric antibiotic therapy must include these potential pathogens. Early cultures can facilitate organism-specific antibiotic therapy. Aggressive treatment with decongestants, topical nasal steroids, mucoevacuants and occasionally antihistamines should be included at maximal tolerated doses. When medical therapy fails, surgical drainage can be a safe and effective management option. Appropriately directed medical, and occasionally surgical, therapy can lead to a dramatic clinical response and provide an improved quality of life in this patient population.