bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bibliometric and visualized analysis of peripartum respiratory complications from 2004 to 2023
Authors: Ye Fan , Wang Teng , Chen Yijiao , Li Fan , Gu Xinyu , Xiao Jie 
Published: October 2024

BackgroundPeripartum respiratory complications are a major reason for pregnant women’s admission to the ICU, even endangers the maternal life. This bibliometric analysis was designed to elucidate the spectrum of diseases and risk factors for various respiratory complications during the peripartum period, as well as the future research directions in this field.MethodsRelevant publications were downloaded from the Web of Science Core Collection on November 1, 2023. CiteSpace was utilized for conducting the scientometric study.ResultsA total of 2,331 articles and reviews on respiratory complications during pregnancy published between 2004 and 2023 were retrieved, comprising 87,244 co-cited references, originating from 568 institutions across 104 countries/regions. The United States emerged as the leading country in this domain, with Harvard University standing out as the most actively engaged institution. Bibliometric analysis reveals that the current research hotspots include “COVID-19 pandemic,” “venous thromboembolism,” “respiratory distress syndrome” and “cardiovascular diseases.” Meanwhile, “venous thromboembolism,” cytokine storm” and supportive management such as “extracorporeal membrane oxygenation” might represent potential future research directions.ConclusionOver the past two decades, research on respiratory system complications in pregnancy has continually evolved. This study contributes to enabling researchers in the related field to understand future research hotspots and trends, providing information on potential collaborators, institutions, countries, and citation references.
The influence of depth of sedation on motor evoked potentials monitoring in youth from 4 to 23 years old: preliminary data from a prospective observational study
Authors: Hudec Jan , Kosinová Martina , Prokopová Tereza , Zelinková Hana , Hudáček Kamil , Repko Martin , Gál Roman , Štourač Petr 
Published: October 2024

IntroductionThe influence of various levels of sedation depth on motor evoked potentials (MEP) reproducibility in youth is still unclear because of a lack of data. We tested the hypothesis that a deeper level of total intravenous anesthesia (TIVA) [bispectral index (BIS) 40 ± 5 compared to 60 ± 5] can affect surgeon-directed MEP and their interpretation in youths.MethodsAll patients received TIVA combined with propofol and remifentanil. TIVA was initially maintained at a BIS level of 60 ± 5. The sedation anesthesia was deepened to BIS level 40 ± 5 before the skin incision. MEP were recorded and interpreted at both BIS levels. The primary endpoint was to evaluate the effect of the depth of sedation on the MEP reproducibility directed and interpreted by the surgical team in each patient separately. The secondary endpoint was to compare the relativized MEP parameters (amplitude and latency) in percentage at various levels of sedation in each patient separately. We planned to enroll 150 patients. Due to the COVID-19 pandemic, we decided to analyze the results of the first 50 patients.ResultsThe surgical team successfully recorded and interpreted MEP in all 50 enrolled patients in both levels of sedation depth without any clinical doubts. The MEP parameters at BIS level 40 ± 5, proportionally compared with the baseline, were latency 104% (97–110%) and the MEP amplitudes 84.5% (51–109%).ConclusionPreliminary data predict that deeper sedation (BIS 40 ± 5) does not affect the surgical team’s interpretation of MEP in youth patients. These results support that surgeon-directed MEP may be an alternative when neurophysiologists are unavailable.
EEG microstate as a biomarker of post-stroke depression with acupuncture treatment
Authors: Wei Conghui , Yang Qu , Chen Jinling , Rao Xiuqin , Li Qingsong , Luo Jun 
Published: October 2024

BackgroundPost-stroke depression (PSD) is a prevalent psychiatric complication among stroke survivors. The PSD researches focus on pathogenesis, new treatment methods and efficacy prediction. This study explored the electroencephalography (EEG) microstates in PSD and assessed their changes after acupuncture treatment, aiming to find the biological characteristics and the predictors of treatment efficacy of PSD.MethodsA 64-channel resting EEG data was collected from 70 PSD patients (PSD group) and 40 healthy controls (HC group) to explore the neuro-electrophysiological mechanism of PSD. The PSD patients received 6 weeks of acupuncture treatment. EEG data was collected from 60 PSD patients after acupuncture treatment (MA group) to verify whether acupuncture had a modulating effect on abnormal EEG microstates. Finally, the MA group was divided into two groups: the remission prediction group (RP group) and the non-remission prediction group (NRP group) according to the 24-Item Hamilton Depression Scale (HAMD-24) reduction rate. A prediction model for acupuncture treatment was established by baseline EEG microstates.ResultsThe duration of microstate D along with the occurrence and contribution of microstate C were reduced in PSD patients. Acupuncture treatment partially normalized abnormal EEG microstates in PSD patients. Baseline EEG microstates predicted the efficacy of acupuncture treatment with an area under the curve (AUC) of 0.964.ConclusionThis study provides a novel viewpoint on the neurophysiological mechanisms of PSD and emphasizes the potential of EEG microstates as a functional biomarker. Additionally, we anticipated the therapeutic outcomes of acupuncture by analyzing the baseline microstates, which holds significant practical implication for the PSD treatment.
Effectiveness of a school-based high-intensity interval training intervention in adolescents: study protocol of the PRO-HIIT cluster randomised controlled trial
Authors: Liu Yong , Barker Alan R. , Adlam Anna-Lynne R. , Li Minghui , Duncombe Stephanie L. , Agbaje Andrew O. , Gu Yaodong , Zhou Huiyu , Williams Craig A. 
Published: October 2024

IntroductionHigh-intensity interval training (HIIT) is an effective strategy for improving a variety of health and fitness outcomes within school settings. Incorporating HIIT into existing physical activity opportunities appears practically feasible, yet the process evaluation and effectiveness of this strategy needs to be further evaluated. Therefore, a PRO-HIIT intervention will be conducted to evaluate the effectiveness of a 12-week school-based HIIT intervention on cardiorespiratory fitness, physical activity, body composition, muscular strength, bone health, cognitive function, wellbeing and academic performance among 12–13-year-olds.Methods and analysisEight classes of year 7 students (12–13-year-olds) from a secondary school in Ningbo, China, will be recruited and randomly allocated into an intervention or control group. While the control group maintains their usual activities, a 6 to 10 min HIIT session will be embedded in the physical education or physical activity lessons five days a week for 12 weeks for the intervention group. Training workshops will be conducted for participants, teachers, and research staff for facilitating the intervention. Outcome data will be collected at three time points: pre- and post-intervention, and two months (summer holiday) upon completion of the intervention. Linear mixed models will be used to analyse the impact of groups (intervention and control), timepoints (pre-, post- and two-month after intervention) and group by time interactions. The implementation process of the intervention will be evaluated using a process evaluation framework.Ethics and disseminationEthics approval is obtained from the Ningbo University Ethics Committee (TY2024002). Results from PRO-HIIT study will be disseminated via peer-reviewed journals, scientific conferences as well as local education system. The study protocol has been retrospectively registered on ClinicalTrials.gov Protocol Registration and Results System (NCT06374732), https://clinicaltrials.gov/study/NCT06374732.
The impact of informal control on the innovation performance of female technology professionals from the perspective of role pressure
Authors: Zeng Xiangfei , Cao Mengyan , Hu Jingjing , Zhang Wenpei 
Published: October 2024

BackgroundWith the rapid advancement of the technology industry, particularly in STEM fields, female professionals have increasingly become key drivers of innovation. Despite this, existing research has seldom examined the psychological impact of informal control on their innovation performance. Therefore, this study distributed questionnaires to female technology professionals in China’s STEM field to investigate the effect of informal control on their innovation performance from a psychological perspective. It further explored the mediating role of role pressure and the moderating role of environmental turbulence in this relationship.MethodsThis study primarily utilized AMOS 24.0 to develop structural equation models, and employed PROCESS 24.0 and SPSS 26.0 for data analysis purposes.ResultsThe findings reveal that informal control positively predicted the innovation performance of female technology professionals in STEM field. Role pressure partially mediates this relationship, while environmental turbulence positively moderates the relationship between informal control and innovation performance among female technology professionals in STEM field.DiscussionTheoretically, this research enriches the individual-level approaches to enhancing management control effectiveness. Practically, it aids managers in focusing on the psychological well-being of female technology professionals in STEM field, thereby facilitating the judicious selection of management control methods. The study’s conclusions aim to provide logical guidance for enterprises to further strengthen their attention and support for female technology professionals in STEM field. Simultaneously, it offers a theoretical foundation for enhancing their innovative capabilities.
Axial rotation affects the cognitive characteristics of spatial ability
Authors: Feng Tian , Zhang Fuchun , Liu Jinzhao , Liang Manqi , Li Yawei 
Published: October 2024

PurposeTo test spatial ability in athletes with different axial rotation experience and analyze their behavioral data to explain the cognitive mechanisms of spatial ability in athletes.MethodsExperiment 1: A total of 147 athletes were selected for the paper-and-pencil mental rotation test (MRT). The athletes were separated according to three sport types: open high-spatial (OH) sport, closed high-spatial (CH) sport, closed low-spatial (CL) sport. Spatial ability testing with a two-factor mixed experimental design of 3 (sport type) × 2 (stimulus type). Experiment 2: In this study, 47 players were selected for computerized mental rotation test, with a three-factor mixed experimental design of 3 (sport type) × 2 (angle: 45°, 90°) × 3 (rotational axis: left–right axis, up–down axis, and front–back axis). Repeated-measures ANOVA was performed to evaluate the data.Results(1) The CH group and OH group outperformed the CL group in the non-embodied task (all ps &lt; 0.003) and the CH group was better than the other groups in the embodied and tasks (all ps &lt; 0.008). (2) Under 45° rotational conditions, the reaction time (RT) for the left–right (LR) and up–down (UD) axes were shorter than that for the front-back (FB) axis (all ps &lt; 0.026). However, under 90° conditions, the RT for FB &lt; LR &lt; UD, with superior accuracy and rotational speed for the FB axis than for the LR and UD axes (all ps &lt; 0.034). (3) Male players from the CH and CL groups had shorter RTs than did those from the OH group at both angles (all ps &lt; 0.047). For female players, the CH group presented a shorter RT than the OH and CL groups did at 90° (all ps &lt; 0.006). (4) No sex difference was found for paper and pencil MRTs, but a male advantage existed only in the CL group for computerized MRTs (p = 0.005).ConclusionThe motor skills associated with axial rotation could promote mental rotation performance and compensate for sex differences in mental rotation ability.
Emotions and interactive tangible tools for math achievement in primary schools
Authors: Saccardo Filippo , Decarli Gisella , Missagia Valentina Irene , Andrao Margherita , Gini Federica , Zancanaro Massimo , Franchin Laura 
Published: October 2024

IntroductionAcquiring mathematical concepts is crucial for students’ academic achievements, future prospects and overall well-being. This study explores the role of emotions in a symbolic number comparison task and the impact of the use of a tangible tool.MethodsFifty-nine healthy children aged 6 to 7 years participated in a between-subject study with two conditions for the modality, digital tools vs the use of pen and paper, and two conditions for emotions, positive vs neutral.ResultsThe study provided evidence that positive emotions can improve task efficiency for pen and paper modality, and the use of the digital tool improves task efficiency with both positive and negative emotions.DiscussionThese findings suggest that addressing emotional factors before engaging in a symbolic task can enhance learning and that interactive technology may give a more significant benefit to students with less positive attitudes toward the task. Incorporating effective teaching methodologies that utilize tangible devices within a positive emotional context can foster engagement and achievement in mathematics, optimizing students’ learning experiences.
Advanced quantitative magnetic resonance imaging of lower extremity muscle microtrauma after marathon: a mini review
Authors: Cheng Yu , Li Xiaokai 
Published: October 2024

This article reviews the existing literature and outlines recent advances in quantitative Magnetic Resonance Imaging (MRI) techniques for the assessment of lower extremity muscle microtrauma following a marathon. Single-modality quantitative MRI techniques include T2 mapping to assess the dynamics of muscle inflammatory edema and variability at the site of injury, Diffusion Tensor Imaging (DTI) to detect subclinical changes in muscle injury, Intravoxel Incoherent Motion (IVIM) imaging to provide simultaneous information on perfusion and diffusion in muscle tissue without the need for intravenous contrast, and Magnetic Resonance Spectroscopy (MRS) to noninvasively detect intramyocellular lipid (IMCL) content in muscle before and after marathon exercise to explain the use of fatty acids as an energy source in skeletal muscle during long-distance running. As well as Chemical Exchange Saturation Transfer (CEST) is particularly suitable for detecting changes in free creatine, pH values and lactate concentrations in muscles before and after exercise, providing a more detailed picture of muscle physiology and chemistry. These metabolic MRI methods enhance the understanding of biochemical alterations occurring in muscles pre- and post-exercise. Multimodal techniques combine different modalities to provide a comprehensive evaluation of muscle structural and functional changes. These advanced techniques aim to better assess microtrauma and guide clinical treatment, though further validation with larger studies is needed to establish their potential over traditional qualitative methods.
Unilateral biportal endoscopic vs. open surgery in the treatment of young obese patients’ lumbar degenerative diseases: a retrospective study
Authors: Ma Tao , Li Junyang , Geng Yongcun , Yan Dengming , Jiang Ming , Tu Xiaoshuang , Chen Senlin , Wu Jingwei , Nong Luming 
Published: October 2024

BackgroundObesity accelerates the development of lumbar disease and increase the risk during surgery. Unilateral biportal endoscopic discectomy (UBE) is a newly developed minimally invasive technique, which refers to the spinal surgery under unilateral double-channel endoscopic surgery. Therefore, the purpose of this study is whether UBE decompression alone can bring good clinical results to young obese patients with lumbar degenerative diseases.MethodsThe patients with lumbar diseases who underwent UBE and open surgery (open discectomy) in our hospital from February 2020 to February 2022 were selected as young (age ≤ 44 years old) and obesity (BMI ≥ 30 kg/m2). The patients were evaluated with VAS, ODI, JOA and modified Macnab score before operation, 1 month, 6 months and 12 months after operation. Nerve root function sensation, muscle strength and tendon reflex were evaluated. The operation time, estimated blood loss, postoperative hospital stay, incidence of postoperative complications and reoperation rate were recorded. MRI quantitative lumbar multifidus muscle (LMM) comparison was performed 12 months after operation.Results77 patients were included, and the scores of VAS, ODI and JOA were similar in the two groups during the last follow-up. There were no difference in nerve root function sensation, muscle strength or tendon reflex. However, one month after operation, the VAS back score and ODI improvement in the UBE group were significantly better than those in the open group, which were 2.44 ± 0.97, 33.10 ± 6.78 and 2.93 ± 0.79 and 36.13 ± 5.84, respectively, with a statistically significant difference (p = 0.020 and 0.038). According to the modified Macnab criteria, UBE group, the excellent and good rate was 97.2%. The excellent and good rate of open group was 97.6%. The estimated blood loss and postoperative hospital stay in UBE group (36.81 ± 17.81, 3.92 ± 1.32) were significantly better than those in open group (104.88 ± 31.41, 6.41 ± 1.94), with a statistically significant difference (p = 0.010). There was no significant difference in operation time between the two groups (p = 0.070). The number of complications in UBE group was 2 (5.6%) and open group was 4 (9.8%). The fat infiltration rate of 19.3%+11.0% in UBE group was significantly lower than that of 27.0%±13.9% in open group (p = 0.010).ConclusionUBE has the advantage of early recovery in the treatment of lumbar degenerative diseases in young obese patients, and reduces the damage to LMM, so it has a good clinical effect.
Discovery of a blood-based miRNA signature that can predict onset of active tuberculosis among household contacts of TB patients
Authors: Daniel Evangeline Ann , Thiruvengadam Kannan , Chandrasekaran Padmapriyadarsini , Hilda Nancy , Umashankar Pavithra , Prashanthi Pooja , Selvachithiram Murugesan , Pattabiraman Sathyamurthi , Bhanu Brindha , Sivaprakasam Amsaveni , Paradkar Mandar , Kulkarni Vandana , Karyakarte Rajesh , Shivakumar Shri Vijay Bala Yogendra , Mave Vidya , Gupta Amita , Hanna Luke Elizabeth 
Published: October 2024

BackgroundNon-sputum based predictive biomarkers capable of identifying individuals with high risk of progression to active tuberculosis (TB) are critical for global TB control. MicroRNAs (miRNAs) are significant regulators involved in TB pathogenesis and hence we aimed to identify a miRNA signature capable of predicting progression to TB disease.MethodsWe compared the differential miRNA expression profile of QuantiFERON supernatants of TB Progressors, defined as healthy household contacts (HHCs) of TB patients, who developed active TB disease during a 2-year follow-up period, and Non-progressors defined as HHCs from the same longitudinal cohort who did not develop TB disease during the entire follow-up period, using the nanostring nCounter platform. Receiver Operator Characteristic (ROC) analysis was performed to evaluate the diagnostic accuracy of the identified miRNA biomarkers, followed by random forest analysis to determine the best predictive model.ResultsWe identified 30 differentially regulated miRNAs between the two groups. Of these, hsa-miR-585-3p and hsa-miR-92a-3p were up-regulated with a maximum fold change of 1.74 and 1.71 respectively, while hsa-miR-223-3p and hsa-miR-451a were down-regulated by −2.05 and −2.04 fold respectively. Random forest analysis revealed that hsa-miR-181a-5p, hsa-miR-204-5p, hsa-miR-197-3p, hsa-miR-92a-3p, hsa-miR-451a, hsa-miR-24-3p, and hsa-miR-487a-3p exhibited 100% accuracy in identifying Progressors. This panel of 7 miRNAs demonstrated excellent diagnostic performance characteristics with 100% sensitivity and specificity.ConclusionWe propose that the identified miRNA signature has the potential to serve as a very useful tool for early identification of individuals who bear the highest risk of progression to TB, so that they can be targeted for timely intervention.
Morphological and molecular identification of Eimeria rajasthani (coccidia: Eimeriidae) in the dromedary camel (Camelus dromedarius) in Riyadh, Saudi Arabia
Authors: Al-Shaebi Esam M. , Al Quraishy Saleh , Omer Sawsan A. , Abdel-Gaber Rewaida , Mohammed Osama B. 
Published: October 2024

IntroductionCoccidiosis is a serious parasitic disease in camels caused by an intestinal protozoan parasite of the genusEimeria, which is linked to significant causes of reduced milk and meat production. In Saudi Arabia, scare literature focused on the coprological investigation of dromedary camels (Camelus dromedarius). To determine the taxonomic status of camel parasite species, we performed morphological characterization of oocysts and genetic analysis (18S rRNAandITS-1gene regions) ofEimeriaspecies collected from camels in Riyadh, Saudi Arabia.MethodsA total of 150 faecal samples were obtained from camels at the old camel market. These samples were tested for the presence ofEimeriaoocysts using the conventional floatation technique before being sporulated in a 2.5% potassium dichromate solution.Eimeriaoocysts were morphologically and molecularly examined and identified, and the infection rate of parasitic infections was determined.ResultsOur findings revealed that the overall frequency of oocysts was 30%. The identified species wasEimeria rajasthani, which had a typical ellipsoidal oocyst shape. Oocystic polar granule, micropyle, micropylar cap, and oocyst residuum are not visible. Sporocysts are oval with stieda body. Sporocyst residuum contains many granules and sporozoites with refractile bodies and nuclei. Genetic analyses of the sequence data from the partial18S rRNAandITS-1gene regions revealed that the sequences obtained fromE.rajasthanioocysts are related to DNA sequences reported fromE. lamaefrom the Alpaca from China, particularly the18S rRNAsequences.ConclusionThis study emphasized the need to use molecular phylogenetic tools to describe camel intestinal coccidian parasites with traditional morphology-based approaches to better understand their biology. For camel husbandry and disease control, more studies should be conducted to better understand the epidemiology of these protozoan parasites.