bluuebunny/crossref_metadata_2025_split huggingface dataset:
Journey to mother baby care: Implementation of a combined care/couplet model in a Level 2 neonatal intensive care unit
Authors: de Salaberry Julie , Hait Valoria , Thornton Kimberly , Bolton Megan , Abrams Maria , Shivananda Sandesh , Kiarash Maryam , Osiovich Horacio 
Published: May 2019

Abstract“Why can't I have my postpartum care in the same room as my baby?” questioned Hilary, a neonatal intensive care unit (NICU) “alumni” parent, during a design event for the new British Columbia's Women's Hospital 70 single family room NICU. This simple yet provocative question was nearly dismissed and the idea of a combined care model lost, since most members of the team thought it was simply “not possible.” Hilary did not give up and continued to raise this idea throughout every design event. It was Hilary's fortitude and sharing of her NICU experience that was the inspiration for the MotherBaby Care unit. The voice of one woman has improved the birth experiences of potentially thousands of mothers and their at‐risk newborns. By honoring women's voices and values in health care, positive changes that matter to women, infants, and families can be made. Mothers also shared: “I knew what was best for me was to be with my baby,” “If I could stand up after my C‐section, I would drag my IV pole to be with my baby!”, “Teach me how to take care of my premature baby before I am ready to go home!” MotherBaby Care is a combined care or “couplet” care where one NICU nurse provides care for a postpartum mother and her at‐risk newborn in the Level 2 NICU. This review describes the journey from innovation and design to the implementation of the MotherBaby Care model.
Metabolic profiles and pharmacokinetics of goitrin in rats through liquid chromatography combined with electrospray ionization–tandem mass spectrometry
Authors: Li Jinhang , Shi Yanhong , Xu Yan , Yang Li , Wang Zhengtao , Han Han , Wang Rui 
Published: May 2019

AbstractSeveral chemical and biological studies have revealed R,S‐goitrin as the main bioactive constituent of Isatis indigotica Fort., responsible for antiviral antiendotoxin activity; however, few pharmacokinetic studies have been conducted. To comprehend the kinetics of R,S‐goitrin and promote its curative application, a rapid and sensitive UHPLC–MS/MS method was developed. The selected reaction monitoring transitions were m/z 130.0 → 70.0 for R,S‐goitrin and m/z 181.1 → 124.0 for the internal standard in a positive‐ion mode. The established UHPLC–MS/MS method achieved good linearity for R,S‐goitrin at 10–2000 ng/mL. The intra‐ and interday accuracy levels were within ±9.7%, whereas the intraday and interday precision levels were <11.3%. The extraction recovery, stability and matrix effect were within acceptable limits. The validated method was successfully applied for the pharmacokinetic analysis of R,S‐goitrin in rats after oral administration. Moreover, a total of six metabolites were structurally identified through UHPLC–Q/TOF–MS. The proposed metabolic pathways of R,S‐goitrin in rats involve demethylation, acetylation, glutathionylation and oxygenation.
Sustainable consumption in China: New trends and research interests
Authors: Shao Jing 
Published: May 2019

AbstractChina is currently the largest CO2 emitter in the world and demonstrates one of the highest levels of energy consumption. The sustainable consumption behavior has increased in China, especially in urban cities. Some clear evidence of this includes food purchasing behavior. Recent studies have also suggested that considering full product information transparency, consumers are willing to pay premium prices for products. With this in mind, sustainable consumption must still be facilitated by related policies, regulations, and tools. This study focuses on sustainable consumption behavior in China and collects and analyzes the literature from the last decade (2007–2017) on the topic. In so doing, it highlights new trends and research topics against the background of circular economy development. The method of systematic review is applied. The review is categorized into several main groups: national policies and regulations, the green awareness of consumers, the definition of related concepts, the barriers between sustainable consumption and the circular economy, and the indicators for circular economy assessment in China. Future research directions are discussed. Furthermore, future challenges are addressed from three perspectives: sustainable consumption facilitating the circular economy, “cradle‐to‐cradle” practices, and the link between the European Union and China. This is a fundamental study in the research domain of sustainable consumption behavior. It provides added value that benefits both academic researchers and decision makers. It also sheds light on the further study of sustainable consumption behavior in China from a macroeconomic perspective.
Percutaneous transaxillary approach for peripheral endovascular interventions
Authors: Thawabi Mohammad , Tayal Rajiv , Hawatmeh Amer , Cohen Marc , Wasty Najam 
Published: May 2019

AbstractObjectivesTo assess the safety and feasibility of percutaneous transaxillary (TAx) access for peripheral endovascular interventions.BackgroundThe common femoral artery (CFA) is the most commonly used access site for peripheral endovascular interventions. However, its use might be precluded in multiple circumstances. The axillary artery is comparable in size to the CFA and is less affected by atherosclerosis. Data regarding its percutaneous use in peripheral endovascular interventions are scarce.MethodsConsecutive patients who underwent percutaneous TAx peripheral endovascular interventions were identified. Demographic and periprocedural data were extracted. Axillary artery access was obtained percutaneously with the arm abducted. A destination sheath was advanced to the relevant vessel. Endovascular interventions were performed using standard devices and techniques. Vascular closure devices were utilized to achieve hemostasis. Primary endpoints included procedural technical success, access‐related complications, and major adverse events (MAEs). Secondary endpoints included cannulation time, total procedure time, fluoroscopy time, and length of stay (LOS).ResultsPercutaneous TAx access was successfully utilized to perform 41 procedures in 29 patients, lacking a suitable conventional access. Three quarters of target vessels were infrainguinal. The lesions of 61% were classified as TransAtlantic Inter‐Society Consensus (TASC) C or D. Access‐related complications occurred in two procedures (5%). No MAEs occurred. Median cannulation time was 12 min, procedure time 135 min, fluoroscopy time 20 min, and LOS 1 day.ConclusionsWhen no suitable access exists for lower extremity catheter‐based interventions, percutaneous TAx approach is a feasible and safe alternative. As such facility with this approach is a valuable asset for interventionalists.
Diagnosis of B‐cell lymphoma from gluteal muscle mass
Authors: Shirzadi Alireza 
Published: May 2019

AbstractA 46‐year‐old man was with a very large mass in his right gluteal muscle and he complained about difficulty in mobility. Incisional biopsy reported a lipomatous lesion; however, clinical presentation was in the favor of muscle sarcoma. Histological analysis after mass excision confirmed the diagnosis of diffuse large B‐cell lymphoma.
Erecta dislocation of the shoulder joint—A rare injury: About four cases
Authors: Diallo Malick , Kassé Amadou N. , Mohamed Limam Sid’Ahmed , Sané Jean C. , Dembélé Badara , Sy Mouhamadou H. 
Published: May 2019

AbstractA nonresolving axillary nerve injury is a rare associated complication to an inferior dislocation of the shoulder joint. This worsen the midterm outcome of the shoulder. So, neurovascular status must be checked by regular clinical testing and by an electromyography in all cases of inferior dislocation of the shoulder joint.
Hydrothermally Synthesized Cobalt Borophosphate as an Electrocatalyst for Water Oxidation in the pH Range from 7 to 14
Authors: Ülker Emine 
Published: May 2019

AbstractThe synthesis of earth‐abundant‐metal‐based, robust, efficient and cost‐effective water oxidation electrocatalysts is necessary for renewable energy conversion processes. In this study, a crystalline cobalt borophosphate (CoBP) was synthesized by reacting CoCl2.6H2O with B2O3 and (NH4)2HPO4 and evaluated as an electrocatalyst for water oxidation catalysis. The electrochemical and electrocatalytic performance of the catalyst towards water oxidation has been investigated by catalyst coating on fluorine doped tin oxide (FTO) electrode in different pH solution. Cyclic voltammetric and chronoamperometric studies were performed for the investigation of pH effect on the catalytic activity. Post‐catalytic studies indicate that CoBP acts as a pre‐catalyst yielding an active phase during the course of electrolysis in the alkaline conditions. The catalyst demonstrated catalytic activity at pH 13.6 with onset potential of 1.46 V (vs. RHE) and Tafel slope of 57 mV dec−1. Electrochemical studies show that catalyst exhibits a current densities of 1 and 10 mA cm−2 at 384 and 441 mV. The catalyst showed a turnover frequency (TOF) of 1.1×10−2 s−1 at overpotential of 300 mV.
Direct Phenolysis Reactions of Unactivated Amides into Phenolic Esters Promoted by a Heterogeneous CeO2 Catalyst
Authors: Rashed Md. Nurnobi , Siddiki S. M. A. Hakim , Touchy Abeda Sultana , Jamil Md. A. R. , Poly Sharmin Sultana , Toyao Takashi , Maeno Zen , Shimizu Ken‐ichi 
Published: May 2019

AbstractThe direct catalytic esterification of amides that leads to the construction of C−O bonds through the cleavage of amide C−N bonds is a highly attractive strategy in organic synthesis. While aliphatic and aromatic alcohols can be readily used for the alcoholysis of activated and unactivated amides, the introduction of phenols is more challenging due to their lower nucleophilicity in the phenolysis of unactivated amides. Herein, we demonstrate that phenols can be used for the phenolysis of unactivated amides into the corresponding phenolic esters using a simple heterogenous catalytic system based on CeO2 under additive‐free reaction conditions. The method tolerates a broad variety of functional groups (>50 examples) in the substrates. Results of kinetic studies afforded mechanistic insights into the principles governing this reaction, suggesting that the cooperative effects of the acid–base functions of catalysts would be of paramount importance for the efficient progression of the C−N bond breaking process, and consequently, CeO2 showed the best catalytic performance among the catalysts explored.
Multiple‐valued computing by dipole‐dipole coupled proteins
Authors: Rakos Balázs 
Published: May 2019

SummaryWe demonstrate through a simple model validated by molecular dynamics‐based simulations that terahertz‐speed, many‐valued logic computations, and digital signal processing, functional for several cycles of operations are potentially possible with electric field‐effect, dipole‐dipole coupled protein architectures with various dipole moment orientations. Many‐valued logic can be applied in various areas, such as artificial intelligence, machine learning, and robotics. Furthermore, programmable logic arrays and field programmable gate arrays can also benefit from its implementation. Even top companies like Intel developed circuits based on such logic (eg, StrataFlash and a NOR flash memory). The present study suggests that multivalued logic states can be stored in a protein with the application of proper external electric fields, and digital signal propagation is potentially achievable using dipole‐dipole coupled molecules, placed few nanometers (on the order of 10 nm) apart. Furthermore, we propose a Dronpa protein‐based ternary logic gate, suitable for universal ternary logic computations. The architectures are potentially operational at room temperature. The proposed operational principle is not restricted to proteins only; it might be applied in case of other types of molecules or artificial structures exhibiting similar behavior.
Class AB amplifier with enhanced slew rate and GBW
Authors: Garde M. Pilar , Lopez‐Martin Antonio , Algueta Jose M. , Carvajal Ramon G. , Ramirez‐Angulo Jaime 
Published: May 2019

SummaryThe design of a micropower class AB operational transconductance amplifier with large dynamic current to quiescent current ratio is addressed. It is based on a compact and power‐efficient adaptive biasing circuit and a class AB current follower using the quasi‐floating gate (QFG) technique. The amplifier has been designed and fabricated in a 0.5‐μm CMOS process. Simulation and measurement results show a slew rate (SR) improvement factor versus the class A version larger than 4 for the same supply voltage and bias currents, as well as enhanced small‐signal performance.
Comparing Pool‐seq, Rapture, and GBS genotyping for inferring weak population structure: The American lobster (Homarus americanus) as a case study
Authors: Dorant Yann , Benestan Laura , Rougemont Quentin , Normandeau Eric , Boyle Brian , Rochette Rémy , Bernatchez Louis 
Published: May 2019

AbstractUnraveling genetic population structure is challenging in species potentially characterized by large population size and high dispersal rates, often resulting in weak genetic differentiation. Genotyping a large number of samples can improve the detection of subtle genetic structure, but this may substantially increase sequencing cost and downstream bioinformatics computational time. To overcome this challenge, alternative, cost‐effective sequencing approaches, namely Pool‐seq and Rapture, have been developed. We empirically measured the power of resolution and congruence of these two methods in documenting weak population structure in nonmodel species with high gene flow comparatively to a conventional genotyping‐by‐sequencing (GBS) approach. For this, we used the American lobster (Homarus americanus) as a case study. First, we found that GBS, Rapture, and Pool‐seq approaches gave similar allele frequency estimates (i.e., correlation coefficient over 0.90) and all three revealed the same weak pattern of population structure. Yet, Pool‐seq data showed FST estimates three to five times higher than GBS and Rapture, while the latter two methods returned similar FST estimates, indicating that individual‐based approaches provided more congruent results than Pool‐seq. We conclude that despite higher costs, GBS and Rapture are more convenient approaches to use in the case of species exhibiting very weak differentiation. While both GBS and Rapture approaches provided similar results with regard to estimates of population genetic parameters, GBS remains more cost‐effective in project involving a relatively small numbers of genotyped individuals (e.g., <1,000). Overall, this study illustrates the complexity of estimating genetic differentiation and other summary statistics in complex biological systems characterized by large population size and migration rates.
Sacubitril/valsartan eligibility and outcomes in the ESC‐EORP‐HFA Heart Failure Long‐Term Registry: bridging between European Medicines Agency/Food and Drug Administration label, the PARADIGM‐HF trial, ESC guidelines, and real world
Authors: Kapelios Chris J. , Lainscak Mitja , Savarese Gianluigi , Laroche Cécile , Seferovic Petar , Ruschitzka Frank , Coats Andrew , Anker Stefan D. , Crespo‐Leiro Maria G. , Filippatos Gerasimos , Piepoli Massimo F. , Rosano Giuseppe , Zanolla Luisa , Aguiar Carlos , Murin Jan , Leszek Przemyslaw , McDonagh Theresa , Maggioni Aldo P. , Lund Lars H. ,   on behalf of the Heart Failure Long‐Term Registry Investigators
Published: May 2019

AimsTo assess the proportion of patients with heart failure and reduced ejection fraction (HFrEF) who are eligible for sacubitril/valsartan (LCZ696) based on the European Medicines Agency/Food and Drug Administration (EMA/FDA) label, the PARADIGM‐HF trial and the 2016 ESC guidelines, and the association between eligibility and outcomes.Methods and resultsOutpatients with HFrEF in the ESC‐EORP‐HFA Long‐Term Heart Failure (HF‐LT) Registry between March 2011 and November 2013 were considered. Criteria for LCZ696 based on EMA/FDA label, PARADIGM‐HF and ESC guidelines were applied. Of 5443 patients, 2197 and 2373 had complete information for trial and guideline eligibility assessment, and 84%, 12% and 12% met EMA/FDA label, PARADIGM‐HF and guideline criteria, respectively. Absent PARADIGM‐HF criteria were low natriuretic peptides (21%), hyperkalemia (4%), hypotension (7%) and sub‐optimal pharmacotherapy (74%); absent Guidelines criteria were LVEF>35% (23%), insufficient NP levels (30%)and sub‐optimal pharmacotherapy (82%); absent label criteria were absence of symptoms (New York Heart Association class I). When a daily requirement of ACEi/ARB ≥ 10 mg enalapril (instead of ≥ 20 mg) was used, eligibility rose from 12% to 28% based on both PARADIGM‐HF and guidelines. One‐year heart failure hospitalization was higher (12% and 17% vs. 12%) and all‐cause mortality lower (5.3% and 6.5% vs. 7.7%) in registry eligible patients compared to the enalapril arm of PARADIGM‐HF.ConclusionsAmong outpatients with HFrEF in the ESC‐EORP‐HFA HF‐LT Registry, 84% met label criteria, while only 12% and 28% met PARADIGM‐HF and guideline criteria for LCZ696 if requiring ≥ 20 mg and ≥ 10 mg enalapril, respectively. Registry patients eligible for LCZ696 had greater heart failure hospitalization but lower mortality rates than the PARADIGM‐HF enalapril group.
Nanostructured Gold Microelectrodes for Non‐enzymatic Glucose Sensor
Authors: Hovancová Jana , Šišoláková Ivana , Vanýsek Petr , Oriňaková Renáta , Shepa Ivan , Vojtko Marek , Oriňak Andrej 
Published: May 2019

AbstractA novel, highly stable, selective, and sensitive non‐enzymatic glucose sensor was developed by simple and effective modification procedure. The modification of gold microelectrodes by electrochemically deposited gold nanoparticles resulted in increase of surface area up to 37 %. The nanostructured surfaces of the gold microelectrodes obtained by different modifications were studied by confocal microscopy, atomic force microscopy, and scanning electron microscopy. The gold nanoclusters exhibit great electrocatalytic properties toward glucose with a wide linear range from 0.5 to 50 mM, with a limit of detection 218 μM, and sensitivity of 185.2 mA mM−1cm−2. Moreover, the modified microelectrodes display good reproducibility, stability, and selectivity in the presence of poisoning compounds. Due to the small dimensions of gold microelectrodes and a very small volume of the sample, the microelectrodes make a contribution to miniaturisation of the system.
Performance evaluation of hybrid solar chimneys for fresh water production
Authors: Hoseini Hamideh , Mehdipour Ramin 
Published: May 2019

AbstractThe hybrid solar chimneys power plant can produce electric energy and fresh water simultaneously. The purpose of this research is to numerically analyze the hybrid solar power plant, using heat transfer mathematical models. In this study, performance of two different cases for power generation is investigated. First, combination of solar chimney and humidifier is investigated, and second, combination of the solar chimney, humidifier, and a condenser is investigated. The effect of solar radiation and water temperature used in the humidifier on the produced electric power and fresh water is investigated. Obtained results of the first case show that adding moisture in the collector entry, it can decrease air weight as much as the radiation of the sun. According to the results obtained, in the integrating solar chimney with the humidifier, generated power increases by higher solar radiation in all three modes, although the increased power of the first case with spraying water of 40, 20, and 10°C is almost 4 times, 2.7 times, and 1.3 times higher in comparison with the classical solar chimney. It is found for the second case that, for increased solar radiation in the above three cases, the humidifier output air temperature increases and the amount of produced water and relative humidity at the output of the humidifier decreases.
Mapping the pathways between recreational cannabis use and mood disorders: A Behaviour Sequence Analysis approach
Authors: Keatley David A. , Walters Isobel , Parke Adrian , Joyce Tara , D. Clarke David 
Published: May 2019

AbstractIssues AddressedAlthough cannabis use is still illegal in most places around the world, it remains a widely used drug. The recreational use of cannabis has been linked to multiple mental wellbeing issues, including psychosis, depression and anxiety. The objective of this study was to investigate the temporal dynamics of cannabis use in relation to mental health issues.MethodsThe current research uses a novel methodological approach, behaviour sequence analysis, to understand the temporal relationship between recreational cannabis use and surrounding issues related to mental wellbeing, in a sample of 61 participants who had written autobiographical accounts online.ResultsThe results indicated a bi‐directional temporal ordering between cannabis use and mood disorders. Cannabis use preceded psychosis and can also exacerbate symptoms of psychosis, depression and anxiety. Findings also suggested that low self‐esteem may be a predictor of future cannabis use.ConclusionsResearch shows a link between mood disorders and recreational cannabis use. The BSA method can be used in applied settings to map pathways in individuals’ life histories.So what?The current study shows the sequential links between cannabis use and psychosis, depression and anxiety. Results show there is no single clear pathway and clinical practitioners should focus on a wider range of factors in individual's case histories.
A novel automated magnetic resonance image segmentation approach based on elliptical gamma mixture model for breast lumps detection
Authors: Biswas Biswajit , Ghosh Swarup Kr , Ghosh Anupam 
Published: May 2019

AbstractThis article introduces a novel semisupervised automated segmentation approach for breast magnetic resonance (MR) image on multicore CPU‐GPU systems. The basic idea of the proposed method is clustering‐based semisupervised classifier devised by elliptical gamma mixture model (EGMM). Parameters of EGMM are identified by the iterative log‐expectation maximization (EM) algorithm. The suggested classifier labels the groups of voxels in an input image first and then classifies the image slices using the EGMM. Two different implementations of the proposed algorithm have been developed based on two different types of high‐performance computing architectures such as graphics processing units (GPUs) and multicore processors. To realize the real‐time segmentation performance of our algorithm with two distinctive architecture, we have tested a set of breast MR images collected from MedPix. Comparison between two architectures in terms of segmentation performance and computational cost is assessed by the analysis of simulation and experimental results.