bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intracranial Volume Post Cranial Expansion Surgery Using Three-Dimensional Computed Tomography Scan Imaging in Children With Craniosynostosis
Authors: Sulong Shukriyah , Alias Azmi , Johanabas Fadzlishah , Yap Abdullah Johari , Idris Badrisyah 
Published: August 2019

Background:
Craniosynostosis is a congenital defect that causes ≥1 suture to fuse prematurely. Cranial expansion surgery which consists of cranial vault reshaping with or without fronto-orbital advancement (FOA) is done to correct the skull to a more normal shape of the head as well as to increase the intracranial volume (ICV). Therefore, it is important to evaluate the changes of ICV after the surgery and the effect of surgery both clinically and radiologically.

Objective:
The aim of this study is to evaluate the ICV in primary craniosynostosis patients after the cranial vault reshaping with or without FOA and to compare between syndromic and nonsyndromic synostosis group, to determine factors that associated with significant changes in the ICV postoperative, and to evaluate the resolution of copper beaten sign and improvement in neurodevelopmental delay after the surgery.

Methods:
This is a prospective observational study of all primary craniosynostosis patients who underwent operation cranial vault reshaping with or without FOA in Hospital Kuala Lumpur from January 2017 until Jun 2018. The ICV preoperative and postoperative was measured using the 3D computed tomography (CT) imaging and analyzed. The demographic data, clinical and radiological findings were identified and analyzed.

Results:
A total of 14 cases (6 males and 8 females) with 28 3D CT scans were identified. The mean age of patients was 23 months. Seven patients were having syndromic synostosis (4 Crouzon syndromes and 3 Apert syndromes) and 7 nonsyndromic synostosis. The mean preoperative ICV was 880 mL (range, 641–1234 mL), whereas the mean postoperative ICV was 1081 mL (range, 811–1385 mL). The difference was 201 mL which was statistically significant (P < 0.001). In comparison, the mean volume increment for syndromic synostosis and nonsyndromic synostosis was 282 mL and 120 mL, respectively. The difference was statistically significant (P < 0.004). Three months post-operation, the copper beaten sign was still present in the CT scan which was statistically not significant in this study (P > 1.0). However, there was 100% (n = 13) improvement of this copper beaten sign. However, the neurodevelopmental delay showed no improvement which was statistically not significant (P > 1.0).

Conclusion:
Surgery in craniosynostosis patient increases the ICV besides it improves the shape of the head. From this study, the syndromic synostosis had better increment of ICV compared to nonsyndromic synostosis.
Neurochemical biomarkers in amyotrophic lateral sclerosis
Authors: Verde Federico , Silani Vincenzo , Otto Markus 
Published: August 2019

Purpose of review
The diagnosis of amyotrophic lateral sclerosis (ALS) still relies mainly on clinical criteria. In present review we will provide an overview of neurochemical ALS biomarkers, which are in the most advanced position on the way towards inclusion into the clinical work-up.

Recent findings
The field of ALS neurology still lacks a neurochemical marker for routine clinical use. However, this is urgently needed, because it would help in diagnosis, prognostic stratification, and monitoring of drug response. Despite this lack of a routinely used biomarker, in the last decade significant progress has been made in the field. In particular, two molecules have been extensively studied – the light chain and the phosphorylated form of the heavy chain of neurofilaments, NFL and pNFH, respectively – which have demonstrated a high diagnostic performance and promising prognostic value and are therefore ready to be introduced into the clinical scenario. On the other hand, we still lack a neurochemical cerebrospinal fluid or blood biomarker reflecting TDP-43 pathology.

Summary
Neurofilaments seem to be ready for clinical use in the early and differential diagnosis of ALS. We also highlight still unresolved issues which deserve further investigation.
Comparative study of 1,2,3-triazole derivatives as corrosion inhibitors of mild steel in sulphuric acid solution
Authors: Elazhary Ilham , Laamari My Rachid , Boutouil Aziz , Bahsis Lahoucine , El Haddad Mohammadine , Anane Hafid , Stiriba Salah-Eddine 
Published: August 2019

PurposeThis paper aims to study the corrosion inhibition of Methyl 2-(benzamido)-2-(4-phenyl-1H-1,2,3-triazol-1-yl) acetate (MBPTA) and Methyl 2-(benzamido)-2-(4-p-tolyl-1H-1,2,3-triazol-1-yl) acetate (MBTTA) in 1 M H2SO4 solution at 25 °C.Design/methodology/approachThe authors have used weight loss measurements, electrochemical impedance spectroscopy (EIS), potentiodynamic polarization, FT-IR, quantum chemical calculations and scanning electron microscopy (SEM) techniques.FindingsThe polarization measurements indicate that both compounds are mixed type inhibitors, and that MBTTA is more effective than MBPTA. The effect of temperature on the corrosion behavior using optimal concentration of MBTTA and MBPTA was studied in the temperature range 298-328 K. SEM was used to examine the morphology of the metal surface. Thermodynamic parameters were calculated and discussed. Monte Carlo simulations were applied to lookup for the most stalls configuration and adsorption energy for the interaction of inhibitors on Fe (1 1 1) interface. The difference in inhibition efficiencies between the two organic inhibitors can be clearly explained in terms of frontier molecular orbital theory.Originality/valueThe authors report on the comparative inhibiting effect of two new 1,4-disubstituted 1,2,3-triazoles, namely Methyl 2-(benzamido)-2-(4-phenyl-1H-1,2,3-triazol-1-yl) acetate (MBPTA) and Methyl 2-(benzamido)-2-(4-p-tolyl-1H-1, 2, 3-triazol-1-yl) acetate (MBTTA) on mild steel corrosion in 1 M H2SO4solution.
Influence of pH level of artificial saliva on corrosion behavior and nickel ion release of a Ni-Cr-Mo alloy: an in vitro study
Authors: Moslehifard Elnaz , Ghasemzadeh Sanaz , Nasirpouri Farzad 
Published: August 2019

Purpose
The purpose of this paper (in vitro) study was to determine the effect of pH of artificial saliva on the corrosion behavior of a Ni-Cr-Mo alloy at 37 ± 1°C.

Design/methodology/approach
The corrosion behavior of a commercially available Ni-Cr-Mo base dental alloy was studied by potentiodynamic polarization and electrochemical impedance spectroscopy techniques. The effect of pH on corrosion and Ni ion release was also investigated by scanning electron microscopy and atomic absorption spectroscopy.

Findings
The results suggested that the order of corrosion rate was: pH3 > pH5 > pH9 > pH7. Corrosion rate in pH3 was significantly different with other pH levels. Nickel depletion significantly occurred in alloy without passivation. The corrosion resistance and ion release of Ni-Cr-Mo alloys in different pH levels of artificial saliva depended on the stability of the passive layer. Acidic pH level severely corrodes Ni-Cr-Mo base metal alloys and increases Ni ion release.

Originality/value
This manuscript describes the relationship between corrosion rate and nickel ion release of a dental Ni-Cr-Mo base alloy as a function of saliva pH examined by electrochemical impedance spectroscopy (EIS), polarization, scanning electron microscopy and energy dispersive X-ray spectroscopy in artificial saliva. The main novelty of this work includes the material/structure/corrosion relationship in artificial saliva with different pH. This property would be very interesting for dental materials applications and clinical dentistry.
Dynamic supplier selection through optimal ranking under two-echelon system
Authors: Ahmad Md Tanweer , Mondal Sandeep 
Published: August 2019

Purpose
With the increasing competition among the industries, they remain under pressure as how to select the best set of suppliers for the competitive edge. Often, it has been challenging to develop an effective set of suppliers due to varied and asymmetric mode of criteria. The purpose of this paper is to develop a responsive chain under original equipment manufacturer (OEM).

Design/methodology/approach
This study proposes a responsive chain under a two-echelon system (TES) of OEM, which needs to collaborate with a set of suppliers at each echelon through an integrated methodology of AHP and TOPSIS. According to the OEM’s criteria, demands and suppliers’ capacity vary with time, therefore they are not static for a longer period. Hence, supplier selection (SS) problem possesses dynamicity in real practice. For this, MILP is used for finding optimal order quantities based on the optimal ranking at each echelon in the multi-period scenario. Subsequently, sensitivity analysis (SA) is conducted through Taguchi method of parameter design (TMPD) to achieve an optimal ranking in the TES.

Findings
This study suggests optimal criteria’s weight, percentage contribution, and flexibility for the suppliers and manufacturers involving through maximum demand strategy at each echelon of OEM. It also provides robust group of suppliers and manufacturers in the TES through optimal ranking and simultaneously in the order allocations. Furthermore, it restricts the number of suppliers and manufactures at each echelon through proposed methodology to obtain the solution in a very short running time.

Originality/value
To validate this model, a real data set for the case of chain conveyor company is used. This adopted methodology can suggest the organization that how the approach should be implemented.
Employee motivation, emotions, and performance: a longitudinal diary study
Authors: Reizer Abira , Brender-Ilan Yael , Sheaffer Zachary 
Published: August 2019

Purpose
Numerous studies have focused on the effect of motivation on performance in the workplace. The purpose of this paper is to evaluate the somewhat overlooked role of positive and negative emotions as potential mediators of this critical association.

Design/methodology/approach
The longitudinal study employed multilevel modeling for assessing the effects of motivation, emotions and work satisfaction on job performance. In total, 116 respondents provided 1,044 responses at nine consecutive measurement points.

Findings
Findings indicated that positive emotions and job satisfaction mediate the positive association between autonomous motivation and performance. Concurrently, negative emotions and decreased job satisfaction mediated the negative associations between controlled motivation and job performance.

Research limitations/implications
The results address only the within-subject and between-subject analysis of temporal variations in emotions and behavior. Future studies can include higher levels of analysis, such as group, team and organizational contexts.

Originality/value
This research contributes to self-determination theory by highlighting the role of emotions in understanding how motivation shapes workplace performance.
Geologic legacy spanning >90 years explains unique Yellowstone hot spring geochemistry and biodiversity
Authors: Payne Devon , Dunham Eric C. , Mohr Elizabeth , Miller Isaac , Arnold Adrienne , Erickson Reece , Fones Elizabeth M. , Lindsay Melody R. , Colman Daniel R. , Boyd Eric S. 
Published: August 2019

SummaryLittle is known about how the geological history of an environment shapes its physical and chemical properties and how these, in turn, influence the assembly of communities. Evening primrose (EP), a moderately acidic hot spring (pH 5.6, 77.4°C) in Yellowstone National Park (YNP), has undergone dramatic physicochemical change linked to seismic activity. Here, we show that this legacy of geologic change led to the development of an unusual sulphur‐rich, anoxic chemical environment that supports a unique archaeal‐dominated and anaerobic microbial community. Metagenomic sequencing and informatics analyses reveal that >96% of this community is supported by dissimilatory reduction or disproportionation of inorganic sulphur compounds, including a novel, deeply diverging sulphate‐reducing thaumarchaeote. When compared to other YNP metagenomes, the inferred functions of EP populations were like those from sulphur‐rich acidic springs, suggesting that sulphur may overprint the predominant influence of pH on the composition of hydrothermal communities. Together, these observations indicate that the dynamic geological history of EP underpins its unique geochemistry and biodiversity, emphasizing the need to consider the legacy of geologic change when describing processes that shape the assembly of communities.
The vaginal microbiome in uterine transplantation
Authors: Jones BP , Saso S , L'Heveder A , Bracewell‐Milnes T , Thum M‐Y , Diaz‐Garcia C , MacIntyre DA , Quiroga I , Ghaem‐Maghami S , Testa G , Johannesson L , Bennett PR , Yazbek J , Smith JR 
Published: August 2019

Women with congenital absolute uterine factor infertility (AUFI) often need vaginal restoration to optimise sexual function. Given their lack of procreative ability, little consideration has previously been given to the resultant vaginal microbiome (VM). Uterine transplantation (UTx) now offers the opportunity to restore these women's reproductive potential. The structure of the VM is associated with clinical and reproductive implications that are intricately intertwined with the process of UTx. Consideration of how vaginal restoration methods impact VM is now warranted and assessment of the VM in future UTx procedures is essential to understand the interrelation of the VM and clinical and reproductive outcomes.Tweetable abstractThe vaginal microbiome has numerous implications for clinical and reproductive outcomes in the context of uterine transplantation.
Market Integration and Market Efficiency under Seasonal Tariff Rate Quotas
Authors: Hillen Judith 
Published: August 2019

AbstractSwitzerland applies seasonal tariff rate quotas (TRQs) for the import of many fruits and vegetables during the domestic harvest season. We examine how this system affects the relationship between Italian and Swiss tomato prices and test for physical market integration and spatial equilibrium conditions over time. We use detailed, transaction‐based data on trade flows and trade costs and estimate an extended parity bounds model, following Barrett and Li (2002). We confirm that in the summer season, when TRQs are in place, markets are inefficient. While quota holders receive positive rents, the marginal rents for importers without quota shares are negative. This inhibits trade flows above the in‐quota import quantity allowed by TRQs. Hence, despite leading to inefficiencies and creating rents for importers, seasonal TRQs are effective in protecting domestic production against competing imports.
Determining Volumetric Shrinkage Trends of Burnt Bone Using Micro‐CT
Authors: Ellingham Sarah , A. Sandholzer Michael 
Published: August 2019

AbstractUnderstanding the degree and pattern of shrinkage undergone by bone when subjected to heating is crucial to accurately deduce a biological profile from incinerated remains. X‐ray microtomography (micro‐CT) enables a nondestructive insight into hard tissue structural changes, while allowing for an accurate documentation of volumetric and trabecular shrinkage. Sheep ribs were experimentally burned at temperatures between 400 and 1000°C in 100°C increments and their volumetric shrinkage was calculated. Observed shrinkage ranged from 14.0% at 400°C to 45.5% at 1000°C. Bones burned at temperatures up to 600°C showed no significant difference, whereas the 700 and 800°C samples exhibited higher shrinkage. Bones burnt at 900 and 1000°C showed significantly higher shrinkage than the other temperature groups. Findings signify the potential of micro‐CT in research on the effects of factors such as diagenesis or burning on the bone density, morphology and microarchitecture.
Women's Authority in Patriarchal Social Movements: The Case of Female Salafi Preachers
Authors: Nielsen Richard A. 
Published: August 2019

AbstractHow do women gain authority in the public sphere, especially in contexts where patriarchal norms are prevalent? I argue that the leaders of patriarchal social movements face pragmatic incentives to expand women's authority roles when seeking new movement members. Women authorities help patriarchal movements by making persuasive, identity‐based arguments in favor of patriarchy that men cannot, and by reaching new audiences that men cannot. I support this argument by examining the rise of online female preachers in the Islamist Salafi movement, using interviews, Twitter analysis, and automated text analysis of 21,000 texts by 172 men and 43 women on the Salafi‐oriented website saaid.net. To show the theory's generality, I also apply it to the contemporary white nationalist movement in the United States. The findings illustrate how movements that aggressively enforce traditional gender roles for participants can nevertheless increase female authority for pragmatic political reasons.
Upregulated SHP‐2 expression in the epileptogenic zone of temporal lobe epilepsy and various effects of SHP099 treatment on a pilocarpine model
Authors: Yue Jiong , Liang Chao , Wu Kefu , Hou Zhi , Wang Lukang , Zhang Chunqing , Liu Shiyong , Yang Hui 
Published: August 2019

AbstractTemporal lobe epilepsy (TLE) is defined as the sporadic occurrence of spontaneous recurrent seizures, and its pathogenesis is complex. SHP‐2 (Src homology 2‐containing protein tyrosine phosphatase 2) is a widely expressed cytosolic tyrosine phosphatase protein that participates in the regulation of inflammation, angiogenesis, gliosis, neurogenesis and apoptosis, suggesting a potential role of SHP‐2 in TLE. Therefore, we investigated the expression patterns of SHP‐2 in the epileptogenic brain tissue of intractable TLE patients and the various effects of treatment with the SHP‐2‐specific inhibitor SHP099 on a pilocarpine model. Western blotting and immunohistochemistry results confirmed that SHP‐2 expression was upregulated in the temporal neocortex of patients with TLE. Double‐labeling experiments revealed that SHP‐2 was highly expressed in neurons, astrocytes, microglia and vascular endothelial cells in the epileptic foci of TLE patients. In the pilocarpine‐induced C57BL/6 mouse model, SHP‐2 upregulation in the hippocampus began one day after status epilepticus, reached a peak at 21 days and then maintained a significantly high level until day 60. Similarly, we found a remarkable increase in SHP‐2 expression at 1, 7, 21 and 60 days post‐SE in the temporal neocortex. In addition, we also showed that SHP099 increased reactive gliosis, the release of IL‐1β, neuronal apoptosis and neuronal loss, while reduced neurogenesis and albumin leakage. Taken together, the increased expression of SHP‐2 in the epileptic zone may be involved in the process of TLE.
Relevance of host tau in tau seeding and spreading in tauopathies
Authors: Ferrer Isidro , Zelaya Maria Victoria , Aguiló García Meritxell , Carmona Margarita , López‐González Irene , Andrés‐Benito Pol , Lidón Laia , Gavín Rosalina , Garcia‐Esparcia Paula , del Rio José Antonio 
Published: August 2019

AbstractHuman tau seeding and spreading occur following intracerebral inoculation of brain homogenates obtained from tauopathies in transgenic mice expressing natural or mutant tau, and in wild‐type (WT) mice. The present study was geared to learning about the patterns of tau seeding, the cells involved and the characteristics of tau following intracerebral inoculation of homogenates from primary age‐related tauopathy (PART: neuronal 4Rtau and 3Rtau), aging‐related tau astrogliopathy (ARTAG: astrocytic 4Rtau) and globular glial tauopathy (GGT: 4Rtau with neuronal deposits and specific tau inclusions in astrocytes and oligodendrocytes). For this purpose, young and adult WT mice were inoculated unilaterally in the hippocampus or in the lateral corpus callosum with sarkosyl‐insoluble fractions from PART, ARTAG and GGT cases, and were killed at variable periods of three to seven months. Brains were processed for immunohistochemistry in paraffin sections. Tau seeding occurred in the ipsilateral hippocampus and corpus callosum and spread to the septal nuclei, periventricular hypothalamus and contralateral corpus callosum, respectively. Tau deposits were mainly found in neurons, oligodendrocytes and threads; the deposits were diffuse or granular, composed of phosphorylated tau, tau with abnormal conformation and 3Rtau and 4Rtau independently of the type of tauopathy. Truncated tau at the aspartic acid 421 and ubiquitination were absent. Tau deposits had the characteristics of pre‐tangles. A percentage of intracellular tau deposits co‐localized with active (phosphorylated) tau kinases p38 and ERK 1/2. Present study shows that seeding and spreading of human tau into the brain of WT mice involves neurons and glial cells, mainly oligodendrocytes, thereby supporting the idea of a primary role of oligodendrogliopathy, together with neuronopathy, in the progression of tauopathies. In addition, it suggests that human tau inoculation modifies murine tau metabolism with the production and deposition of 3Rtau and 4Rtau, and by activation of specific tau kinases in affected cells.
Birth and coming of age of islet autoantibodies
Authors: Bonifacio E , Achenbach P 
Published: August 2019

SummaryThis review takes the reader through 45 years of islet autoantibody research, from the discovery of islet-cell antibodies in 1974 to today’s population-based screening for presymptomatic early-stage type 1 diabetes. The review emphasizes the current practical value of, and factors to be considered in, the measurement of islet autoantibodies.
Serum complexes between C1INH and C1INH autoantibodies for the diagnosis of acquired angioedema
Authors: López-Lera A , Garrido S , Nozal P , Skatum L , Bygum A , Caballero T , López Trascasa M 
Published: August 2019

SummaryAcquired angioedema due to C1-inhibitor (C1INH) deficiency (AAE) is caused by secondary C1INH deficiency leading to bradykinin-mediated angioedema episodes. AAE typically presents in adulthood and is associated with B cell lymphoproliferation. Anti-C1INH autoantibodies (antiC1INHAbs) are detectable in a subset of AAE cases and considered a hallmark of the disease. When free antiC1INHAbs and malignant tumors are not detectable, diagnosis relies on the finding of low C1INH levels and/or function, lack of family history and SERPING1 mutations, age at onset and low or undetectable C1q levels, none of which is specific for AAE. We tested the diagnostic value of a novel enzyme-linked immunosorbent assay (ELISA) for the detection of circulating complexes between C1INH and antiC1INHAbs (C1INH–antiC1INHAb) in the serum of 20 European AAE patients characterized on the basis of their complement levels and function. Free antiC1INHAbs were detected in nine of 20 patients [six of immunoglobulin (Ig)G class, two of IgM class and one simultaneously presenting IgG and IgM classes], whereas C1INH–antiC1INHAb complexes were found in 18 of 20 of the AAE cases, regardless of the presence or absence of detectable free anti-C1INHAbs. Of note, nine of 20 patients showed negative free antiC1INHabs, but positive C1INH–antiC1INHAb complexes in their first measurement. In the cohort presented, IgM-class C1INH–antiC1INHAb are specifically and strongly associated with low C1q serum levels. Detection of C1INH–antiC1-INHAbs provides an added value for AAE diagnosis, especially in those cases in whom no free anti-C1INH antibodies are detected. The link between IgM-class C1INH–antiC1INHAb complexes and C1q consumption could have further implications for the development of autoimmune manifestations in AAE.