bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategies to Facilitate Service Utilization Among Youth at Risk for HIV: A Randomized Controlled Trial (ATN 149)
Authors: Swendeman Dallas , Rotheram-Borus Mary Jane , Arnold Elizabeth Mayfield , Fernández Maria Isabel , Comulada W. Scott , Ishimoto Kelsey , Gertsch William , Murphy Debra A. , Ocasio Manuel , Lee Sung-Jae , Lewis Katherine A. ,   The Adolescent HIV Medicine Trials Network (ATN) CARES Team, Abdalian Sue Ellen , Bolan Robert , Bryson Yvonne , Chaplin Antwon , Cortado Ruth , Donahue Catherine , Duan Naihua , Flynn Risa , Fournier Jasmine , Jimenez Sergio , Kerin Tara , Klausner Jeffrey , Kussin Jody , Lightfoot Marguerita , Milburn Norweeta , Mosafer Jasmine , Moses Aaron , Nielsen Karin , Ramos Wilson , Reback Cathy J. , Rezvan Panteha Hayati , Tang Wenze , Tapia Yara , Thomas Demi , Urauchi Stacey , Weiss Robert E. 
Published: November 2024

Abstract
Sexual and gender minority youth (SGMY) are vulnerable to acquiring HIV and need HIV prevention and health services, but may have competing needs. A prior analysis found that PrEP use reports increased in a combination intervention study arm with coaching, peer support, and automated text-messages. This paper examines ancillary support and healthcare services utilization as secondary intervention objectives. SGMY (N = 895, 40% Black, 29% Latino) in Los Angeles and New Orleans were recruited from May, 2017 to August, 2019 and randomized to four intervention conditions: (a) automated text-messaging and monitoring intervention (AMMI), (b) AMMI plus peer support online (AMMI+PS), (c) AMMI plus strengths-based coaching by near-peer paraprofessionals (AMMI+C), or (d) all three (AMMI+PS+C). Intent-to-treat multivariate regression analyses evaluated the interventions’ efficacy on past 4-month reports of ancillary support services use, having a regular healthcare provider, receiving care from doctor’s office or clinic and mental health specialists, and participation in mental health support groups and HIV prevention programs. Ancillary services utilization reports declined from 40% of youth reporting an average of 4.4 services at baseline to 22.6% reporting 2.5 services by 24 months. Food, housing, transportation, and other basic services were utilized most frequently. Youth in the two coaching interventions maintained higher reports of services use over time compared to AMMI-only (both OR 1.23, 95%CI 1.12–1.35) and to AMMI+PS (both OR 1.20 95%CI 1.08–1.33). Our coaching intervention may support SGMY to stay engaged in support services. Results may be limited by self-report biases. It is unclear if these services are related to better long-term outcomes.
LaCour!: enabling research on argumentation in hearings of the European Court of Human Rights
Authors: Held Lena , Habernal Ivan 
Published: November 2024

AbstractWhy does an argument end up in the final court decision? Was it deliberated or questioned during the oral hearings? Was there something in the hearings that triggered a particular judge to write a dissenting opinion? Despite the availability of the final judgments of the European Court of Human Rights (ECHR), none of these legal research questions can currently be answered as the ECHR’s multilingual oral hearings are not transcribed, structured, or speaker-attributed. We address this fundamental gap by presenting LaCour!, the first corpus of textual oral arguments of the ECHR, consisting of 154 full hearings (2.1 million tokens from over 267 h of video footage) in English, French, and other court languages, each linked to the corresponding final judgment documents. In addition to the transcribed and partially manually corrected text from the video, we provide sentence-level timestamps and manually annotated role and language labels. We also showcase LaCour! in a set of experiments that explore the interplay between questions and dissenting opinions. Apart from the use cases in legal NLP, we hope that law students or other interested parties will also use LaCour! as a learning resource, as it is freely available in various formats at https://huggingface.co/datasets/TrustHLT/LaCour.
Elementary School Teachers’ and Counselors’ Decisions on Referring Students for Evaluation: The Impact of ADHD Traits, Achievement, and Giftedness
Authors: Tamsut Avital , Asadi Hattem , Sinai Gal Nahum , Saka Noa , Pollak Yehuda 
Published: November 2024

AbstractThe present study examined the effect of ADHD-related traits, academic-achievement level, and giftedness label on elementary school teachers’ and counselors’ referral recommendations for assessment. 532 teachers and counselors were presented with one of 12 vignettes describing a hypothetical pupil. Participants were asked to report the likelihood they would refer the pupil for ADHD diagnosis and address them during a high-level interdisciplinary school-team meeting (HISTM). High ADHD-related traits (effect size 0.359) and low academic-achievement (effect size 0.070) and their interaction were significantly related to a higher likelihood of referral. Further analysis revealed that lower academic achievement was related to a higher likelihood of referral only when ADHD-related traits were not indicated (p < .005). The status of giftedness label was not found to be significant (p > .05). These findings indicate that mainly ADHD-related traits and, to a lesser degree, low academic-achievement influence teachers’ decisions to refer pupils for ADHD diagnosis and address them in HISTM.
Teaching and learning cybersecurity for European youth by applying interactive technology and smart education
Authors: Blažič Andrej Jerman , Blažič Borka Jerman 
Published: November 2024

AbstractThis paper presents a new developed methodology for teaching and learning subjects that although are very important in the modern digital society are neglected in high school education programs: cybersecurity and cyber safety. A Study among the EU high schools in 2021–2022 revealed that computer science teachers are not regularly upgrading their knowledge and do not have cybersecurity topics included in the educational program for computer science and informatics. The development and the implementation of an interactive education program of cybersecurity topics for high school students enabled a flexible approach for teaching cybersecurity to be be implemented in several EU based high schools The new curriculum offer many tools for active learning like interactive videos, quizzes, games, and live cases of cyber threats and in the same time apply the teaching of the aligned protective methods. During the implementation of the cybersecurity education was found that the applied methodology enhances the interactions between the teachers and the students by presenting and discussing examples encountered when using digital services on the internet and by applying several innovative approaches presented in the 24 fiches. The effectiveness of the approach was evaluated through surveys and interviews but final assessment of the acquired student skills was done at the international Capture tThe Flag game contest. In the discussion section the paper provide an assessment of the applied model and recommendations.
Assessment of faecal sludge quality, heavy metal contamination, and ecological risk: implications for sustainable agriculture
Authors: Odirile Phillimon T. , Obuseng Veronica C. , Moshoeshoe Mohau , Tshenyego Lamong , Mbongwe Bontle 
Published: November 2024

AbstractPit latrines represent the predominant form of on-site sanitation in Botswana, posing unique challenges in faecal sludge (FS) management. The key concerns revolve around FS extraction, treatment, and safe disposal. Currently, co-treatment with wastewater is the primary approach, but it strains wastewater treatment plants (WWTPs) and compromises effluent quality. This study comprehensively assesses FS quality from pit latrines and evaluates the potential health risks when used in agriculture for soil improvement/amendment. Systematic sampling of soils at various depth intervals, approximately 30 cm apart, was conducted, followed by extensive laboratory analysis, including determination of heavy metals (copper, iron, lead, cadmium, zinc, manganese, and arsenic) using inductively coupled plasma atomic emission spectroscopy (ICP-OES) and nutrient analysis using ion chromatography (IC). The findings unequivocally demonstrate that FS from VIP (ventilated improved pit) latrines poses no significant health risks due to heavy metal content. Specifically, Geo-accumulation Index (Igeo) values for nickel (Ni), chromium (Cr), and arsenic (As) were consistently negative, indicating negligible risk of environmental contamination. Copper (Cu) concentrations averaged 40.36 mg/kg in samples collected from Mogoditshane and 591.61 mg/kg in those collected from Broadhurst (Gaborone, Botswana) with Igeo values indicating a moderate pollution risk. Nutrient analysis showed high levels of nitrogen (NO3−), with concentrations reaching 4.47 × 103 mg/kg in some samples, and phosphorus (PO43−) levels as high as 3.9 × 104 mg/kg. These findings highlight its agricultural potential for soil amendment, though prudent management is needed to mitigate eutrophication. The study advocates for separate FS treatment, resolving co-treatment operational challenges and enhancing sustainability. Implementing these recommendations promises to address FS management issues, bolster food security, and enhance Botswana’s ecological well-being.
Hierarchical Cubes: Gibbs Measures and Decay of Correlations
Authors: Jansen Sabine , Neumann Jan Philipp 
Published: November 2024

AbstractWe study a hierarchical model of non-overlapping cubes of sidelengths $$2^j$$

2
j

, $$j\in {\mathbb {Z}}$$

j
∈
Z

. The model allows for cubes of arbitrarily small size and the activities need not be translationally invariant. It can also be recast as a spin system on a tree with a long-range hard-core interaction. We prove necessary and sufficient conditions for the existence and uniqueness of Gibbs measures, discuss fragmentation and condensation, and prove bounds on the decay of two-point correlation functions.
The Early Infancy of a Parent and Baby Mental Health Unit: A Reflection
Authors: Isobel Sophie , Green Alison , Lim-Gibson Sylvia 
Published: November 2024

Abstract

Purpose
This article describes the experience of establishing a new parent and baby mental health unit, including challenges in the first year of operation. The article aims to narrate the experience for the purpose of informing other new mental health services and contributing to service development knowledge.

Description
The analogy of the early infancy period is used to highlight the parallel process of adjustment, confidence and identity formation occurring as part of the unit development and by the parents who are admitted.

Assessment
Key challenges are presented as “We had a baby and moved house at the same time”, “We had a baby with someone we just met”, “We had ghosts in our communal nursery” and “We were juggling the baby and the bathwater”.

Conclusion
The establishment of a new unit provides an opportunity to reflect on the complexity of building workforce, service and clinical capacity within the constraints of public health services. The challenges along the way have helped to build empathy for the experiences of the admitted parents who equally find that things have not gone how they have planned, while finding emerging opportunities for growth, resilience and change.
Oxytocin Protects Against Corticosterone-Induced DA Dysfunction: An Involvement of the PKA/CREB Pathway
Authors: Chaipunko Sirinun , Sookkua Tichaporn , Nopparat Chutikorn , Chutabhakdikul Nuanchan 
Published: November 2024

Abstract
Chronic stress disrupts dopamine (DA) transmission, adversely affecting mood and contribution to neuropsychiatric disorders like ADHD, autism, schizophrenia, anxiety, depression, and drug addiction. The neuropeptide oxytocin (OXT) plays a key role in social cognition, bonding, attachment, and parenting behaviors. In addition, OXT can modulate the activity of the HPA axis, counteracting the effects of stress, and alleviating fear and anxiety. However, whether OXT can mitigate stress-induced DA dysfunction and the underlying mechanisms remains unclear. This study investigated the neuroprotective effects of OXT on corticosterone (CORT) induced DA dysfunction in the neuroblastoma cell line SH-SY5Y. The results revealed that CORT decreases the levels of intracellular signaling molecules associated with DA function, including phosphorylated tyrosine hydroxylase (pTH), phosphorylated cAMP response element-binding protein (pCREB), and protein kinase A (PKA). Interestingly, pretreatment with OXT mitigated CORT-induced DA dysfunction through its potent PKA activator properties. In addition, the neuroprotective effect of OXT was abolished by atosiban (an OXT receptor antagonist) or H89 (a PKA inhibitor). Our results suggest that OXT protects dopaminergic neuroblastoma cells from CORT-induced DA dysfunction, potentially through the involvement of oxytocin receptors and the PKA/CREB signaling pathway. These findings contribute to the understanding of the neurobiological mechanisms underlying stress resilience and highlight potential pathways for developing targeted treatments that leverage the neuroprotective properties of OXT to address disorders characterized by DA dysregulation and impaired stress responses.
Scientifically Together, Politically Apart?
Authors: Viciana Hugo , Astobiza Aníbal M. , Fasce Angelo , Hannikainen Ivar R. 
Published: November 2024

AbstractScience education is generally perceived as a key facilitator in cultivating a scientifically literate society. In the last decade, however, this conventional wisdom has been challenged by evidence that greater scientific literacy and critical thinking skills may in fact inadvertently aggravate polarization on scientific matters in the public sphere. Supporting an alternative “scientific update hypothesis,” in a series of studies (total N = 2087), we show that increased science’s epistemology literacy might have consequential population-level effects on the public’s alignment with scientific results. In one exploratory study and a pre-registered national online survey, we first show that understanding scientific epistemology predicts refusal of pseudoscientific beliefs and higher scores in a methodology of science test. We also find and replicate a propensity for epistemologically literate citizens to endorse the norm of belief updating and the communicated scientific consensus following both ideologically congruent and incongruent scientific results. Notably, after 2 months of first being presented with scientific results on politically controversial issues, a one standard deviation higher score in epistemological literacy is associated with a 14% increase in the odds of individuals switching their beliefs to align with the scientifically communicated consensus. We close by discussing how, on the face of ideological incongruity, a general understanding of scientific epistemology might foster the acceptance of scientific results, and we underscore the need for a more nuanced appreciation of how education, public comprehension of scientific knowledge, and the dynamics of polarization intersect in the public sphere.
Die vielen „Zwei Welten“. Gelebte Diversität im ehemaligen Bonner Diplomatenstadtteil Bad Godesberg
Authors: Ebner Johannes 
Published: November 2024

Zusammenfassung
Obwohl von der Migrations- und Stadtforschung weitgehend übersehen, sind auch bürgerlich geprägte, prosperierende Stadtteile vermehrt mit migrationsbezogener Diversität und damit zusammenhängenden Konflikten konfrontiert. Dieser Beitrag untersucht verschiedene Facetten des alltäglichen Zusammenlebens in einem hochdiversen bürgerlichen Stadtteil mit großem muslimischem Bevölkerungsanteil. Auf der Grundlage fünfjähriger Feldforschung im ehemaligen Bonner Diplomatenstadtteil Bad Godesberg untersucht diese Studie die komplexe Gemengelage verschiedener Gruppen von „Etablierten“ und „Außenseitern“, die im Zuge mehrerer Transformations- und Migrationsschübe entstanden ist. Dazu schließt der Beitrag an zwei Forschungslinien an, die sich verschiedenen Facetten des „Making und Un-Making of Boundaries“ in hochdiversen urbanen Quartieren widmen: die rekonstruktive Diversitätsforschung und Norbert Elias’ relationale Theorie der Gruppenbeziehungen. Er zeigt, (1) wie sich das Zusammenleben durch den lokalen Strukturwandel (z. B. durch den Funktions- und Bedeutungsverlust von Stadt und Stadtbezirk und durch die zunehmende Etablierung der bildungsaffinen „arabischen Community“) verändert, (2) wie (in welchen Situationen und Konstellationen, entlang welcher Differenzkategorien etc.) dies verschiedene Godesbergerinnen und Godesberger wahrnehmen und erzählen, und (3) welche Orte zu Räumen der Begegnung oder des Konflikts werden. Die Analysen bieten Einblicke in lebensweltliche Konflikt‑, Grenzziehungs- und Aushandlungspraktiken und legen nahe, Polarisierung und Diversifizierung als tagesrhythmisches Nach- und sozialräumliches Nebeneinander zu begreifen.
Hospital to Funeral Home Hand-Off of the Decedent Patient with a Viral Hemorrhagic Fever
Authors: Patrick Amie , Yannie Marco , Santillán Perla , Bliley Eric , Diman Krystina , Reece Morris , Cooper Kaila , Doll Michelle 
Published: November 2024

Abstract
Purpose of Review
Viral Hemorrhagic Fevers (VHF), such as those caused by ebolavirus and Marburgvirus, present a global health threat due to their high fatality rates and potential for rapid transmission. We aim to develop a Standard Operational Plan (SOP) for the safe handoff transfer of highly infectious decedents from hospitals to funeral homes. This addresses the gap in existing protocols to ensure infection control and public health safety.

Recent Findings
Recent research highlights the necessity of infection prevention in handling the bodies of highly infectious decedents. The 2014–2015 Ebola outbreak underscored the role of funeral homes practices and hospitals handoff transfer procedure in disease transmission. However, a standardized handoff process between hospitals and funeral homes remains undeveloped.

Summary
Developing a SOP involved collaboration between healthcare professionals, funeral homes, and state health departments. Key findings include the preference for cremation for highly infectious decedents, removal of jewelry before hospital admission, and the use of decedent lifts to ensure safe handling. The SOP emphasizes collaboration and adherence to updated CDC and NETEC guidelines. This SOP is a model for other healthcare facilities, promoting public health safety and infection control during the handoff process of highly infectious decedents.
Fluctuations of prolonged grief disorder reactions in the daily life of bereaved people: an experience sampling study
Authors: Lenferink L. I. M. , Terbrack E. , van Eersel J. H. W. , Zuidersma M. , Franzen M. , Riese H. 
Published: November 2024

Abstract
Loss-adaptation has been described as being characterized by ‘waves of grief’, which may result in a Prolonged Grief Disorder (PGD). Although this assumption about the fluctuating nature of grief is supported by theoretical work, it is not (yet) supported by empirical work. We are the first to explore to what extent PGD reactions fluctuate in everyday life and whether fluctuations in PGD reactions are related to overall PGD levels using experience sampling methodology (ESM). Data from 38 bereaved individuals (74% women, on average 6 years post-loss, 47% lost a parent) were analyzed. For two weeks, five times per day, participants reported on the severity of 11 PGD reactions in the past three hours (ESM-PGD). At baseline, overall PGD severity (B-PGD) in the past two weeks was assessed with telephone-interviews using the Traumatic Grief Inventory–Clinician Administered. Root Mean Square of Successive Differences (RMSSD) were calculated to reflect fluctuations in ESM-PGD. Spearman correlations between RMSSD values of the 11 ESM-PGD reactions and B-PGD scores were computed. Mean B-PGD scores were below the clinical cut-off. Some fluctuations in ESM-PGD reactions were found, as indicated by varying RMSSD values, but also floor effects were detected. B-PGD levels were related to RMSSD values for ESM-PGD (ρ between 0.37 and 0.68, all p <.05; and between 0.36 and 0.63 after removal of floor effects). We found that (some) ESM-PGD reactions fluctuated in everyday life. This may offer new theoretical insights into loss-adaptation, which may result in optimizing PGD treatment.
Alpha-synuclein Fibrils Inhibit Activation of the BDNF/ERK Signaling Loop in the mPFC to Induce Parkinson's Disease-like Alterations with Depression
Authors: Ma Zhuoran , Xu Yan , Lian Piaopiao , Wu Yi , Liu Ke , Zhang Zhaoyuan , Tang Zhicheng , Yang Xiaoman , Cao Xuebing 
Published: November 2024

AbstractDepression (Dep) is one of the most common concomitant symptoms of Parkinson's disease (PD), but there is a lack of detailed pathologic evidence for the occurrence of PD-Dep. Currently, the management of symptoms from both conditions using conventional pharmacological interventions remains a formidable task. In this study, we found impaired activation of extracellular signal-related kinase (ERK), reduced levels of transcription and translation, and decreased expression of brain-derived neurotrophic factor (BDNF) in the medial prefrontal cortex (mPFC) of PD-Dep rats. We demonstrated that the abnormal phosphorylation of α-synuclein (pS129) induced tropomyosin-related kinase receptor type B (TrkB) retention at the neuronal cell membrane, leading to BDNF/TrkB signaling dysfunction. We chose SEW2871 as an ameliorator to upregulate ERK phosphorylation. The results showed that PD-Dep rats exhibited improvement in behavioral manifestations of PD and depression. In addition, a reduction in pS129 was accompanied by a restoration of the function of the BDNF/ERK signaling loop in the mPFC of PD-Dep rats.
Nonspecific increase of αβTCR+ double-negative T cells in pediatric rheumatic diseases
Authors: Dossybayeva Kuanysh , Zhubanova Gulsamal , Mussayeva Assel , Mukusheva Zaure , Dildabayeva Aiken , Nauryzbayeva Galiya , Akhmaltdinova Lyudmila , Orumbayeva Ulbolsyn , Tanko Matthew , Poddighe Dimitri 
Published: November 2024

Abstract
Background
An increased number of double-negative T (DNT) cells expressing the αβ T cell receptor (αβ+DNT cells) is one of the diagnostic criteria for autoimmune lymphoproliferative syndrome (ALPS). Moreover, these cells are expanded in a widely used murine model for lupus. However, the homeostasis of αβ+DNT cells remains inadequately investigated in rheumatic disorders, especially in pediatric patients.

Methods
In this cross-sectional, prospective, and observational study, children with rheumatic disorders and healthy controls were recruited to analyze the quantity and characteristics of circulating DNT cells using flow cytometry.

Results
Overall, the two study groups did not differ in their total DNT cell pool in the bloodstream. However, the number of αβ+DNT cells was significantly higher in rheumatic children than that in the controls, whereas the γδ+DNT cells remained similar. This expansion in the circulating pool of αβ+DNT cells was comparable across different rheumatic diseases, all showing significant differences from the controls in this regard. Moreover, no significant correlation was found between αβ+DNT cell numbers and disease activity.

Conclusions
These preliminary results indicate that circulating αβ+DNT cells are significantly expanded in children with rheumatic disorders; however, this finding appears to be a nonspecific (disease-unrelated) marker of autoimmunity. Further and larger studies are necessary to better investigate and define the role of DNT cells in pediatric rheumatic diseases.

Graphical abstract