bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of Nonenzymatic Benzoic Acid Detection on PdSn/GCE/Vulcan XC‐72R Prepared via Polyol Method
Authors: Kazıcı Hilal Çelik , Yayla Müge , Ulaş Berdan , Aktaş Nahit , Kivrak Hilal 
Published: March 2019

AbstractIn this study a PdSn based sensor was developed for the determination of benzoic acid (BA) in foods. A carbon (Vulcan XC‐72R) supported PdSn catalyst was prepared via polyol method and its surface electronic and chemical properties were investigated by advanced surface analytical techniques such as scanning electron microscopy (SEM), X‐ray diffraction spectroscopy (XRD), X‐ray Photoelectron Spectroscopy (XPS), temperature‐programmed reduction with H2 (TPR‐H2) and transmission electron microscopy (TEM). Electrochemical measurements were performed by employing cyclic voltammetry (CV) and differential pulse voltammetry (DPV) techniques on PdSn/GCE/Vulcan XC‐72R electrode. The developed sensor showed a wide linear range up to 10 mM with a 0.77 μM low limit of detection (LOD) as well as high stability. Further experiments were performed on food samples containing BA to achieve real sample measurements. For real sample measurements, PdSn/GCE/Vulcan XC‐72R electrode was used for the determination of BA in different kinds of samples such as mayonnaise, ketchup and carbonated beverages.
Ten‐year time trends in mental and physical health correlates of weight/shape overvaluation
Authors: Santana Danilo Dias , Mitchison Deborah , Griffiths Scott , Appolinario Jose Carlos , da Veiga Gloria Valeria , Touyz Stephen , Hay Phillipa 
Published: March 2019

AbstractObjectiveTo investigate the relationships between weight/shape overvaluation, health‐related quality of life (HRQoL) and functional role impairment (days out of role [DOR]) in the general population over 11 years.MethodFive cross‐sectional surveys of men and women representative of the South Australian population were conducted in 2005, 2008, 2009, 2015, and 2016 (ntotal = 15,140). Data were collected on demographics, overvaluation, HRQoL, DOR, and eating disorder behaviours.ResultsBetween 2005 and 2016, the prevalence of moderate overvaluation increased from 18.1% to 40.0%, marked overvaluation from 7.5% to 23.7%, and extreme overvaluation from 3.1% to 9.2% (all p < 0.001). Overvaluation at any level was associated with more DOR in 2005 but not in 2016, and the association between HRQoL impairment and overvaluation weakened over time.ConclusionAlthough the population prevalence of overvaluation has increased significantly in the past decade, the impairment associated with it appears to have reduced.
Underground microseismic monitoring of a hydraulic fracturing operation for CBM reservoirs in a coal mine
Authors: Jiang Zhizhong , Li Quangui , Hu Qianting , Chen Jiufu , Li Xuelong , Wang Xiaoguang , Xu Yangcheng 
Published: March 2019

AbstractHydraulic fracturing can evidently improve the coalbed methane production in underground coal mines, but it is difficult to delimit the stimulated area accurately. In order to evaluate the stimulated area, microseismic (MS) monitoring technique is proposed to investigate the seismic responses of the induced fractures of hydraulic fracturing. Three coal seams were targeted to be treated in a coal mine. An array of geophones was set along the underground roadway to detect the MS signals caused by HF. In order to verify the result of MS monitoring, water content of each coal seam has been measured before and after HF treatment. The results showed that a series of MS events were detected during the entire HF process, and a sharp MS event usually occurred during the first hour of HF process. The energy of the sharp MS event had higher magnitude than others. The MS distribution exhibited complex morphological features. The directionless MS response was distributed over a radius of less than 40 m but tended to be significantly conjugated with a radius of more than 40 m. HF could stimulate both the coal seam and the rock layers nearby. The achievable stimulated area in the coal seam was determined to be 50 m × 50 m according to the MS density and water content. The stimulated area in terms of MS density was easily found to be broader than the area of water direct intrusion. The present study indicated that MS monitoring technique could potentially be used for evaluation of HF in underground coal mine.
Challenging the spanning hypothesis at short horizons: Evidence from Norway
Authors: Valseth Siri 
Published: March 2019

AbstractThe spanning hypothesis states that the yield curve reflects all available information about future yields. This paper challenges the hypothesis by investigating the predictive power of bond market order flow while controlling for principal components extracted from the current yield curve. The results show that order flows aggregated from interdealer trades in Norwegian government bonds can predict yield changes and excess returns both in‐sample and out‐of‐sample at the daily and weekly horizons. This suggests that bond dealers possess information about future bond yields that is not yet incorporated into the yield curve. Forecasts based on microstructure data can thus be valuable for short term investors.
Tholeiitic basalts of Deccan large igneous province, India: An overview
Authors: Manu Prasanth M.P. , Hari K.R. , Santosh M. 
Published: March 2019

The Deccan large igneous province (DLIP) of Peninsular India is predominantly composed of tholeiitic basalts with a minor amount of alkaline, carbonatite, and silicic rocks. The tholeiitic basalts of DLIP are enriched in incompatible trace elements and divisible into low‐Ti basalts (TiO2 < 2.5; Ti/Y < 500) and high‐Ti basalts (TiO2 > 2.5; Ti/Y > 500). Despite variable total REE content, both low‐Ti and high‐Ti basalts exhibit almost similar geochemical patterns in the chondrite‐ and primitive‐ mantle‐normalized diagrams. The mantle potential temperature (Tp) of high‐Ti tholeiites estimated at Ca.1368°C, which is consistent with an ambient mantle temperature (1300–1400°C) whereas the Tp of low‐Ti tholeiites is around 1553°C, which indicates its derivation from the mantle plume axis. Extensive assimilation of the crustal components into the ascending plume have masked the nature and compositional characteristics of both high‐ and low‐Ti basalts. The low‐Ti basalts indicate significant contamination with crustal components than the high‐Ti basalts. The geochemical and isotopic compositions indicate the involvement of multiple mantle components. In general, the differentiated tholeiites of DLIP are the products of plume and depleted sections of the mantle with or without contributions from the continental crust. The main phase of Deccan magmatism intensely affected the atmosphere and hydrosphere, which was a possible trigger for the mass extinction event at the K–Pg boundary.
Tumor immune microenvironment characteristics of papillary thyroid carcinoma are associated with histopathological aggressiveness and BRAF mutation status
Authors: Means Casey , Clayburgh Daniel R. , Maloney Lauren , Sauer David , Taylor Matthew H. , Shindo Maisie L. , Coussens Lisa M. , Tsujikawa Takahiro 
Published: March 2019

AbstractBackgroundPapillary thyroid carcinoma (PTC) follows an indolent course; however, up to 30% of patients develop recurrent disease requiring further treatment. Profiling PTC immune complexity may provide new biomarkers for improved risk prediction.MethodsImmune complexity profiles were quantitatively evaluated by multiplex immunohistochemistry (mIHC) in archived tissue sections from 39 patients with PTC, and were assessed for correlations with aggressive histopathological features based on the presence of lymphovascular invasion and/or extrathyroidal extension, and BRAF V600E mutational status.ResultsmIHC revealed two distinct immune clusters stratifying patients: a lymphoid‐inflamed group (higher CD8+ T cells, reduced dendritic and mast cells) and a myeloid/hypo‐inflamed group that correlated with aggressive pathological features. BRAF mutation was not associated with aggressive pathological features but did correlate with increased mast cell density.ConclusionsDistinct immune microenvironments exist in PTC correlating with pathological aggressiveness. Immune‐based biomarkers associated with possible tumor‐immune interactions may be used for risk stratification.
Combined vaginal administration of nystatin, diiodohydroxyquin, and benzalkonium chloride versus oral metronidazole for the treatment of bacterial vaginosis
Authors: Chooprasertsuk Wichinee , Somboonporn Woraluk , Soontrapa Sukree , Salang LingLing , Amnatbuddee Siriruthai 
Published: March 2019

AbstractObjectiveTo compare combined vaginal administration of nystatin, diiodohydroxyquin, and benzalkonium chloride versus oral metronidazole for the treatment of bacterial vaginosis (BV).MethodsA randomized controlled trial was conducted among women diagnosed with BV using the Amsel criteria (n=90) at a university hospital in Khon Kaen, Thailand, between June 27, 2017, and April 30, 2018. The oral metronidazole group (n=44) received 400 mg of metronidazole, administered three times per day. The combined vaginal tablet group (n=46) received a vaginal suppository once daily, which comprised nystatin (100 000 U), diiodohydroxyquin (100 mg), and benzalkonium chloride (7 mg). Treatment was administered for 7 days in both groups. Follow‐up visits at 14 and 42 days assessed treatment outcomes and adverse effects.ResultsRemission of BV occurred among 41 (93%) women in the oral metronidazole group and 39 (85%) women in the combined vaginal tablet group. The adjusted relative risk was 0.92 (95% confidence interval 0.80–1.06). The rate of nausea and/or vomiting was significantly higher in the oral metronidazole group than that in the combined vaginal tablet group.ConclusionTreatment efficacy of the combined vaginal tablet versus oral metronidazole was equivalent.Clinical trial registration: TCTR20170627001 (www.clinicaltrials.in.th).
Laparoscopic lateral suspension for pelvic organ prolapse in a case with difficulty in performing laparoscopic sacrocolpopexy
Authors: Okada Yoshiyuki , Hayashi Tokumasa , Sawada Yugo , Tokiwa Shino , Yoshio Yuko , Gonocruz Sheryl G , Kitagawa Yasuhide , Nomura Jimmy 
Published: March 2019

IntroductionMesh fixation at the promontory is the most important procedure in laparoscopic sacrocolpopexy. We present a case of pelvic organ prolapse wherein sacrocolpopexy was converted to lateral suspension intraoperatively due to tissue weakness of the promontory.Case presentationA 66‐year‐old woman with a sensation of bulge in the vagina presented to our clinic. She was diagnosed with uterine prolapse (grade III). Laparoscopic sacrocolpopexy was planned; exposure of the promontory and mesh fixation at the vesicovaginal and rectovaginal space could be smoothly performed. However, handling the needle at the promontory was impossible due to tissue weakness of the anterior longitudinal ligament of the sacrum. Consequently, mesh fixation was converted to lateral suspension.ConclusionDifficult mesh fixation at the promontory is not rare in laparoscopic sacrocolpopexy. Lateral suspension may be useful as a trouble‐shooting procedure for laparoscopic sacrocolpopexy, and surgeons performing laparoscopic sacrocolpopexy should know this procedure.
Laparoscopic pelvic organ prolapse repair by mesh interposition following radical cystectomy
Authors: Abe Hirokazu , Fan Bo , Huang Tingwen , Komori Hiroka , Ochi Atsuhiko , Suzuki Koichiro , Kitagawa Yasuhide , Shiga Naoki 
Published: March 2019

IntroductionThe present study aims to introduce laparoscopic treatment by the interposition of polypropylene mesh for a pelvic organ prolapse in females following radical cystectomy for treating muscle‐invasive bladder carcinoma.Case presentationThe patients included two women aged 77 and 79 years with symptomatic enterocele following radical cystectomy and ileal conduit urinary diversion. We performed laparoscopic sacrospinous colpopexy using polypropylene and polypropylene/ePTFE composite meshes.ConclusionNo recurrent prolapse occurred during 26 and 14 months of follow‐up after the operation. No severe perioperative complications were noted. This is a first report on cases of laparoscopic sacrospinous colpopexy for post‐cystectomy pelvic organ prolapse. Our procedure could be safely performed in two patients with post‐cystectomy pelvic organ prolapse.
Threats to adhesive/dentin interfacial integrity and next generation bio‐enabled multifunctional adhesives
Authors: Spencer Paulette , Ye Qiang , Song Linyong , Parthasarathy Ranganathan , Boone Kyle , Misra Anil , Tamerler Candan 
Published: March 2019

AbstractNearly 100 million of the 170 million composite and amalgam restorations placed annually in the United States are replacements for failed restorations. The primary reason both composite and amalgam restorations fail is recurrent decay, for which composite restorations experience a 2.0–3.5‐fold increase compared to amalgam. Recurrent decay is a pernicious problem—the standard treatment is replacement of defective composites with larger restorations that will also fail, initiating a cycle of ever‐larger restorations that can lead to root canals, and eventually, to tooth loss. Unlike amalgam, composite lacks the inherent capability to seal discrepancies at the restorative material/tooth interface. The low‐viscosity adhesive that bonds the composite to the tooth is intended to seal the interface, but the adhesive degrades, which can breach the composite/tooth margin. Bacteria and bacterial by‐products such as acids and enzymes infiltrate the marginal gaps and the composite's inability to increase the interfacial pH facilitates cariogenic and aciduric bacterial outgrowth. Together, these characteristics encourage recurrent decay, pulpal damage, and composite failure. This review article examines key biological and physicochemical interactions involved in the failure of composite restorations and discusses innovative strategies to mitigate the negative effects of pathogens at the adhesive/dentin interface. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 107B:2466–2475, 2019.
Nanoglass‐based balloon expandable stents
Authors: Kumar Gideon Praveen , Yuan Suyue , Cui Fangsen , Branicio Paulo Sergio , Jafary‐Zadeh Mehdi 
Published: March 2019

AbstractHere, a prototypical metallic nanoglass is proposed as a new alloy for balloon expandable stents. Traditionally, the stainless steel SS 316L alloy has been used as a preferred material for this application due to its proper combination of mechanical properties, corrosion resistance, and biocompatibility. Recently, metallic glasses (MGs) have been considered as promising materials for biodevice applications. MGs often display outstanding mechanical properties superior to those of conventional metallic alloys and overcome some of the weaknesses of SS 316L, such as radiopacity, stainless steel allergy, and thrombosis‐induced restenosis. However, commonly used monolithic MGs, which have an amorphous homogeneous microstructure, suffer from lack of ductility that is necessary for deployment of balloon expandable stents. In contrast, nanoglasses, that is, amorphous alloys with heterogeneous microstructure, exhibit enhanced ductility which makes them promising materials for balloon expandable stents. We evaluate the feasibility of a prototypical Zr64Cu36 nanoglass with a grain size of 5 nm for balloon expandable stents by performing finite element method modeling of the stent deployment process in a coronary artery. We consider the BX‐Velocity stent design and the nanoglass mechanical properties calculated from atomistic simulations. The results suggest that nanoglasses are suitable materials for balloon expandable stent applications. © 2019 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 108B:73–79, 2020.
Brain region‐specific regulation of histone acetylation and efflux transporters in mice
Authors: You Dahea , Shin Hye Min , Mosaad Fatimah , Richardson Jason R. , Aleksunes Lauren M. 
Published: March 2019

AbstractMultidrug resistance protein 1 (MDR1) and breast cancer resistance protein (BCRP) protect the brain by restricting the passage of chemicals across the blood‐brain barrier. Prior studies have demonstrated the epigenetic regulation of MDR1 and BCRP in cancer cells treated with histone deacetylase (HDAC) inhibitors that enhance histone acetylation and gene transcription. In the present study, we tested the in vivo effects of two HDAC inhibitors, valproic acid (VPA; 400 mg/kg) and apicidin (5 mg/kg), on Mdr1 and Bcrp transporter expression in brain regions of adult male mice injected intraperitoneally daily for 7 days. VPA increased Mdr1 protein expression in the striatum (70%) and Bcrp protein in the midbrain (30%). Apicidin enhanced striatal Mdr1 protein (30%) and hippocampal Bcrp protein (20%). Transporter induction correlated with increased histone H3 acetylation in discrete brain regions. In conclusion, HDAC inhibitors upregulate transporter proteins in vivo, which may be important in regulating regional xenobiotic disposition within the brain.
An efficient protein immobilization strategy: protein encapsulated in nano molecular cages
Authors: Xia Yu‐Pei , Dou Yi‐Fang , Pei Xin‐Jiang , Cao Yi‐Ping , Zhi Gao‐Ying , Zhang Dong‐Hao , Hu Liandong 
Published: March 2019

AbstractBACKGROUNDTo immobilize protein firmly and maintain its native conformation, a ‘nano molecular cage’ was designed to encapsulate bovine serum albumin (BSA) on the surface of poly(methyl methacrylate) (PMMA) magnetic microspheres by cross‐linking poly(ethylene imine) (PEI) chains.RESULTSThe amount of BSA adsorbed on PMMA@PEI microspheres decreased significantly from 70.6 to 7.6 mg g−1 microsphere after desorption under high ionic strength. A similar phenomenon could also be observed for BSA adsorbed on PMMA@PEI‐CB (Cibacron Blue F3GA) microspheres. In contrast, the amount of BSA encapsulated in molecular cages only decreased a little after desorption. Furthermore, conformational analysis by Fourier transform infrared spectroscopy (FTIR) showed that the contents of α‐helices and β‐sheets decreased slightly by 3.3 and 0.3% respectively on encapsulating BSA in molecular cages. Furthermore, the effects of various factors, including glutaraldehyde amount, cross‐linking time and temperature, on BSA encapsulation were investigated.CONCLUSIONThe results demonstrated that molecular cages could not only immobilize protein firmly but also maintain its native conformation. Therefore molecular cage encapsulation is suggested to be a potentially valuable protocol in enzyme immobilization. © 2019 Society of Chemical Industry
Physicochemical comparison of precipitated calcium carbonate for different configurations of a biogas upgrading unit
Authors: Baena‐Moreno Francisco M , Price Cameron AH , le Saché Estelle , Pastor‐Pérez Laura , Sebastia‐Saez Daniel , Reina Tomas R 
Published: March 2019

AbstractBACKGROUNDThis paper presents a physicochemical comparison of the solid products obtained from two alternative processes that recycle waste sodium carbonate (Na2CO3) solution, which is produced following the absorption of CO2 in a biogas upgrading unit. Chemical regeneration processes offer an attractive alternative to the energetically demanding standard physical methods. In the first process, sodium hydroxide (NaOH) is regenerated as a precipitate from the chemical reaction of Na2CO3 with calcium hydroxide (Ca(OH)2). The second process shows a path to obtain a valuable sodium chloride (NaCl) and calcium carbonate (CaCO3) rich brine from calcium chloride (CaCl2) acting as a precipitant agent. In both processes, precipitated calcium carbonate (PCC) is obtained as the most valuable by‐product, but with varying properties owing to the different origin.RESULTSThe purpose of this work is to analyze physicochemically both variations of PCCs obtained and examine the differences between these solid samples in order to determine which method produces more desirable characteristics in the final product. To this end, Fourier transform infrared (FTIR) spectroscopy, Raman spectroscopy, X‐ray diffraction (XRD) and scanning electron microscopy (SEM) were employed as characterization methods. The results reflect that both PCCs have a calcite crystal structure, or morph, being as both PCC products originate from CaCl2 that is more similar to commercial calcium carbonate calcite.CONCLUSIONThese results confirmed that a pure CaCO3 valuable by‐product can be obtained from a biogas upgrading unit with several industrial applications. © 2019 Society of Chemical Industry
Partially thrombosed aneurysm of the medial marginal vein
Authors: Khodarahmi Iman , Alizai Hamza , Adler Ronald 
Published: March 2019

AbstractLower extremity superficial venous aneurysms are occasionally encountered by clinicians and are almost always located above the knee. Very few cases of aneurysm of the medial marginal vein in the most distal part, near the origin of the great saphenous vein, have been reported. We present a case of partially thrombosed aneurysm of the medial marginal vein, and briefly review the imaging characteristics and treatment options of this entity. Being aware of the existence of superficial venous aneurysms may help clinicians in their differential diagnosis of foot masses and choice of appropriate treatment.
Development of Polyoxyethylene Zwitterionic Surfactants for High‐Salinity High‐Temperature Reservoirs
Authors: Kamal Muhammad Shahzad , Hussain Syed M. Shakil , Fogang Lionel Talley , Malik Izhar A. 
Published: March 2019

AbstractSubstantial efforts are underway to improve the recovery factor from existing oil reserves to meet the ever‐growing global oil demand. Surfactants are known to increase oil recovery through reducing interfacial tension (IFT) and/or altering the rock wettability. The selection of surfactants for high‐salinity high‐temperature oil fields is a challenging task owing to poor thermal stability, precipitation, and adsorption of surfactants on reservoir rocks. Sulfobetaine‐based polyoxyethylene zwitterionic surfactants have shown excellent thermal and surface properties. However, their solubility in high‐salinity brines becomes poor particularly with a long hydrophobic tail (>C17). Recently, we synthesized such types of surfactants by incorporating ethylene oxide (EO) units into the hydrophobic tail, which improved the solubility in formation water (213,734 ppm) and seawater (SW) (57,643 ppm). In this work, we investigated the IFT, thermal stability, rheological behavior, and foaming properties of two polyoxyethylene zwitterionic surfactants having different degrees of ethoxylation. Aging experiments exhibited excellent thermal stability and no change in the chemical structure was detected. The surfactant with lesser EO units (EASB‐1a) showed a lower IFT compared to the surfactant with higher EO units (EASB‐1b). Rheological studies revealed that the addition of both surfactants reduced the viscosity of the acrylamide copolymer. However, the effect of EASB‐1a was more prominent compared to that of EASB‐1b. The surfactant with a higher degree of ethoxylation showed lower adsorption compared to the surfactant with a lesser degree of ethoxylation. Both surfactants showed excellent foamability and foam stability compared to the commercial surfactants. Excellent thermal stability, water solubility under harsh reservoir conditions, foaming properties, and lower adsorption make them a suitable choice for high‐temperature, high‐salinity reservoirs.