bluuebunny/crossref_metadata_2025_split huggingface dataset:
Updating the critical steps of the quality implementation framework: a protocol for an umbrella review of reviews
Authors: Hald Kathrine , Ording Anne Gulbech , Jorsal Martin , Midtgaard Julie , Ellis Louise A , Spanos Samantha , Pagano Lisa , Fisher Georgia , Braithwaite Jeffrey , Johnsen Søren Paaske 
Published: November 2024

IntroductionImplementation science focuses on improving the dissemination, uptake and adoption of evidence into practice. Over the last decade, implementation science research has proliferated, particularly in healthcare and social science. The key synthesis of implementation frameworks conducted by Meyers and colleagues in 2012, and the resulting Quality Implementation Framework, has yet to be updated to incorporate this research. This protocol proposes an umbrella review of reviews (RORs) to synthesise the literature since 2012 on implementation science in the fields of healthcare and social science and provides recommendations for an updated Quality Implementation Framework.Methods and analysisThis ROR will be conducted and reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Four academic databases (PubMed, Scopus, PsycINFO and Web of Science) will be used to identify peer-reviewed meta-analyses, systematic reviews and scoping reviews published in the English language since January 2012 and report on the development, application or update of one or more implementation frameworks in healthcare or social science contexts. Multiple reviewers will be involved in the screening of articles and extraction of data, and the quality of reviews will be assessed using the AMSTAR (A MeaSurement Tool to Assess systematic Reviews) 2. The outcome of interest is the content of implementation science frameworks reported in the included reviews. The content of these frameworks will be synthesised, aggregated and mapped to the four phases and 14 steps outlined in the original Quality Implementation Framework using both deductive and inductive analysis.Ethics and disseminationEthics approval is not required as this ROR protocol and the resulting ROR do not involve primary data collection. The protocol as well as the ROR will be disseminated in peer-reviewed journals.PROSPERO registration numberCRD42023475994.
Traditional, complementary and integrative medicine therapies for the treatment of mild/moderate acute COVID-19: protocol for a systematic review and network meta-analysis
Authors: Li Anqi , Guyatt Gordon , Chu Derek , Thabane Lehana , Busse Jason W , Sadeghirad Behnam , He Qingyong , Ge Long , Hao Qiukui , Vohra Sunita , Brinkhaus Benno , Witt Claudia M , Li Yachan , Krishnan Geetha , Agoritsas Thomas , Wieland Lisa Susan , Chaturvedi Sarika , Kothari Kavita U , Patwardhan Bhushan , Fang Min , Kong Lingjun , Ren Jun , Lee Myeong Soo , Cheung Angela , Okwen Patrick M , Downey Bernice , Ang Lin , Zhu Jialing , Zhang Yuqing 
Published: November 2024

BackgroundIncreasing evidence has emerged for traditional, complementary and integrative medicine (TCIM) to treat COVID-19 which requires systematic summaries of the net benefits of interventions against standard care and one another. The study aims to conduct a systematic review and network meta-analysis (NMA) regarding TCIM therapies for treating mild/moderate acute COVID-19, potentially informing the WHO guideline development and clinical decision-making.Methods and analysisWe will search Embase, MEDLINE, Virtual Health Library on Traditional Complementary and Integrative Medicine, Cochrane Central Register of Controlled Trials, WHO’s International Clinical Trials Registry Platform with additional searches of Chinese and Korean literature sources for randomised controlled trials comparing TCIM with placebo, standard care, no treatment or with an alternate type of TCIM to treat COVID-19. We will limit the search dates from 2020 to 28 March 2024. Reviewers will, in duplicate, screen eligible articles, extract data and evaluate the risk of bias. We will conduct frequentist network meta-analyses for network comparisons and each outcome. We will assess the certainty of evidence using the Grading of Recommendations Assessment, Development and Evaluation approach and classify interventions from most to least effective or harmful.Ethics and disseminationThis NMA is based on the existing trials and data which is not subject to ethical approval. We will publish the NMA in a peer-reviewed journal. This may provide methodological reference and clinical evidence for TCIM on future epidemic-prone diseases.PROSPERO registration numberCRD42024517321.
Cost–benefit analysis of mammography screening: the perspective of Nigerian healthcare providers
Authors: Nduka Ifeoma Jovita , Umeh Ifeoma Blessing , Okafor Chukwudi Victor , Orih Daniel , Nduka Sunday Odunke , Ekwunife Obinna Ikechukwu 
Published: November 2024

IntroductionThere is no national breast cancer screening implemented in Nigeria. The National Cancer Control Plan (NCCP) has a goal of making screening services and early detection of cancer available for all Nigerians. Health financing is predominantly through out-of-pocket (OOP) spending. As it could take a while for the NCCP to figure out a financing mechanism to make screening widely available, it is necessary to assess if mammography screening could be potentially funded by OOP by ascertaining the value that eligible women place on it. This study assessed the cost–benefit of mammography screening from the healthcare provider’s perspective.MethodsThis hospital-based cross-sectional study assessed the potential benefit of mammography using participants’ willingness to pay (WTP) for the service. Average WTP was determined using contingent valuation. Binary logistic regression was used to assess predictors of WTP acceptance while multiple linear regression was used to model the relationship between the independent variables and WTP amount. The cost of mammography was estimated from the healthcare provider’s perspective. Probabilistic sensitivity analysis was used to account for parameter uncertainty. The benefit–cost ratio (BCR) was calculated.Results767 respondents participated in the study. The stated average WTP amount (minimum-maximum) was US$10.26 (US$0.0–US$46.20). Participants who had never noticed a breast change were 2.5 times more likely to be willing to pay for mammography screening. A unit increase in income level led to a US$9.185 increase in WTP amount for mammography screening. Also, a unit increase in breast self-examination led to a US$2.797 increase in WTP amount for mammography screening. The average cost (minimum-maximum) of mammography was US$23.02 (US$13.20–US$33.00). The BCR of mammography screening was 0.45 (95% CI 0.44 to 0.46).ConclusionsMammography screening is not cost–beneficial to the healthcare provider when clients are asked to pay OOP. This highlights the need to explore sustainable health financing mechanisms to support mammography screening in Nigeria.
Atrial arrhythmia and heart failure in adult patients with congenital heart disease: a retrospective cohort study
Authors: Lauwers Charlotte , Troost Els , De Meester Pieter , Moons Philip , Vandenberk Bert , Ector Joris , Haemers Peter , Budts Werner , Van De Bruaene Alexander 
Published: November 2024

BackgroundAtrial arrhythmias (AA) and heart failure (HF) are major causes of hospitalisation in adult congenital heart disease (ACHD). This study aimed to evaluate the temporal relationship between AA and HF onset, the association between HF and the success of radiofrequency ablation (RFA), and how HF influences outcomes in patients with AA.MethodsIn this single-centre retrospective cohort study, data from 3995 patients with ACHD were analysed. Dates of first AA and HF presentations were documented, and outcomes of RFA, including acute and long-term success, were assessed. All-cause mortality was compared between patients with AA and those with both AA and HF.ResultsThe median age at last follow-up was 33 years (IQR 26–42). AA was observed in 348 patients (8.7%), and HF in 256 (6.4%). Among patients who developed both AA and HF (n=130), AA preceded HF in 79% of cases, with a median interval of 6 years (IQR 2–13) before HF diagnosis. In the remaining cases, AA occurred after HF diagnosis (median 2 years, IQR 1–6). RFA was performed in 119 patients (34.2%), 45 of whom had HF. Two years after RFA, 72% of patients were free from AA recurrence. Patients without HF had higher acute success rates (98% vs 90%) and lower recurrence rates (48% vs 76%) than those with HF. Patients with AA with HF had worse overall survival compared with those without HF.ConclusionsIn patients with ACHD, AA frequently precedes HF by several years. RFA can be an effective treatment for AA, but acute success is lower and recurrence rate higher when HF is present.
Onyx dilution reduces time to resolution of chronic subdural hematomas after middle meningeal artery embolization
Authors: Hung Alice , Yang Wuyang , Das Oishika , Wang Xihang , Ran Kathleen , Ejimogu Emeka , Abdulrahim Mostafa , Nakamura Ryan , Hui Ferdinand , Yedavalli Vivek , Jackson Christopher M , Huang Judy , Tamargo Rafael J , Caplan Justin M , Gonzalez L Fernando , Xu Risheng 
Published: November 2024

BackgroundThe benefit of distal embolite penetration for middle meningeal artery (MMA) embolization in chronic subdural hematomas (cSDH) remains controversial.ObjectiveTo compare the use of diluted Onyx with undiluted Onyx in the management of cSDH.MethodsThis is a retrospective study of patients with cSDH who underwent MMA embolization using Onyx 18 at our institution. The study population was divided into two subgroups based on whether the Onyx used was diluted or not. Baseline characteristics and technical aspects were compared. Primary outcome was cSDH resolution at follow-up. Secondary outcomes included time to resolution and duration of procedure. Univariate statistical analysis was performed.ResultsOf the 111 MMA embolizations performed at our institution, 99 were performed using Onyx 18 only. Within this cohort, 53 (53.5%) cases used standard Onyx and 46 (46.5%) cases used diluted Onyx. The diluted Onyx group had significantly greater volume of embolic agent used measured radiographically (P<0.001). There was no significant difference in duration of procedure. The percentage of cSDH resolution at last follow-up was similar between the two groups (P=0.98), but the time to resolution was significantly shorter in the diluted Onyx group (P=0.02).ConclusionThe use of diluted Onyx for MMA embolization is associated with greater embolization volume achieved under similar procedural times. While the percentage of patients who achieved cSDH resolution with diluted Onyx is similar to that for standard Onyx, the time to cSDH resolution is significantly shorter. Adoption of Onyx dilution can be considered in MMA embolization for cSDH.
Using photovoice to investigate patient experiences of lupus nephritis in Canada
Authors: Cardwell Francesca S , Elliott Susan J , Barber Megan R W , Cheema Kim , George Sydney , Boucher Adrian , Clarke Ann Elaine 
Published: November 2024

ObjectiveLupus nephritis (LN) is a major cause of morbidity and mortality, affecting up to 60% of patients with systemic lupus erythematosus (SLE). The perspectives of patients with SLE have been explored; however, little is known of the lived experiences of patients with LN.MethodsPatients aged ≥18 years with biopsy-proven pure or mixed International Society of Nephrology/Renal Pathology Society Class III, IV or V LN were purposefully recruited from a Canadian lupus cohort to participate in a photovoice (visual–narrative participatory research method) exercise. Participants took photos of what LN means to them, impacts on daily life and factors impacting LN management. Photos were shared and discussed in focus groups.Results13 individuals with LN participated (92.3% were female; mean (SD) age was 41.7 (14.0) years). The mean (SD) number of photos shared per participant was 4.2 (0.9). Photos (n=54) depicted activities/settings that contribute to well-being (n=15), the participants themselves (n=13), healthcare experiences (n=10), home (n=4), community (n=2), friends (n=2), work (n=2) and other challenges (n=6). All participants described physical and psychosocial impacts of living with LN. Although 12 mentioned activities/settings that contribute to well-being (eg, time in natural environments), participants were consistently reminded of limitations imposed by LN due to physical symptoms, challenges presented by the physical environment and the altered life trajectories experienced. Participants discussed the dual burden of LN and the associated medication journey; side effects and medication-related financial challenges were highlighted by ten and five participants, respectively.ConclusionsParticipants reported a substantial psychosocial burden associated with altered life trajectories, the dual burden of LN and the associated medication journey, and the conflicting role of the physical environment. The need for flexibility (ie, from employers, themselves) is an essential component of navigating altered life trajectories.
Comparison of a novel methadone rotation method with other commonly used methods
Authors: Cunningham Elaine , DiBiagio Nicole , O’ Connell Florry , Flannery Maedhbh , Cronin Michael , Murphy Marie , O’Leary Mary Jane , Kiely Fiona , Lowney Aoife C 
Published: November 2024

ObjectivesTo compare a novel method of methadone rotation used in a specialist palliative care inpatient unit (SPCU) in Cork, Ireland, with rapid titration methods using Perth and Brisbane Protocols as well as the Edmonton method of methadone rotation.MethodsA retrospective chart review was performed in March–June 2022. All patients who completed rotation to methadone during 2018–2019 in the SPCU were included. 2018–2019 was selected to study a population not affected by the coronavirus pandemic. Oral morphine equivalent (OME) was calculated using the opioid conversion chart. From the OME, the expected daily methadone dose was calculated using the Perth, Brisbane and Edmonton methods. These figures were then compared directly with the actual methadone doses achieved using our dosing schedule.ResultsA comparison of the expected doses using the Perth and Brisbane rapid titration protocols and stable daily dose achieved revealed that the stable methadone dose was significantly lower than both rapid titration protocols (p=<0.0001) and (p=0.0035, respectively). However, a comparison of the expected dose using the Edmonton method and the dose achieved did not determine any significant difference (p=0.7602).ConclusionsThis is the first evaluation of a novel Irish method of methadone rotation and demonstrates a lower overall daily methadone dose compared with established protocols.
Spatial and seasonal determinants of arthropod community composition across an agro-ecosystem landscape
Authors: Burgess P. , Betini G.S. , Cholewka A. , deWaard J.R. , deWaard S. , Griswold C. , Hebert P.D.N. , MacDougall A. , McCann K.S. , McGroarty J. , Miller E. , Perez K. , Ratnasingham S. , Reisiger C. , Steinke D. , Wright E. , Zakharov E. , Fryxell J.M. 
Published: November 2024

We used Malaise traps to sample arthropod community composition at biweekly intervals across an agroecosystem landscape in southern Ontario, Canada, to evaluate the relative impact of site spacing, seasonal timing, weather conditions, local plant community attributes, and agricultural extent across the local landscape on spatial and temporal variation in arthropod community composition. The 15 field sites sampled spanned a wide gradient of agricultural extent that in isolation had a strong impact on spatial variation in arthropod community composition. DNA metabarcoding of the samples identified >10 000 different arthropod biodiversity index numbers. Local variation in plant community composition and canopy cover best explained variation in arthropod community dissimilarity. Weather variables followed closely in explanatory power, driven primarily by seasonal variation in temperature. Significant effects of time remained after accounting for environmental variables, with little independent effect of spatial distance. The proportion of agricultural land at the landscape scale had little detectable effect after controlling for the influence of the other environmental variables. Our results suggest that plant community composition, cover, weather conditions, and seasonality structured the arthropod community to considerable degree.
Twist and turn: elastohydrodynamics of microscale active fibres
Authors: Lisicki Maciej 
Published: November 2024

AbstractCellular locomotion often involves the motion of thin, elastic filaments, such as cilia and flagella, in viscous environments. The manuscript serves as a general introduction to the topic of modelling microscale elastohydrodynamics. We briefly characterise the specific features of biological filaments that affect their propulsion modes, and discuss the discrete and continuous theoretical frameworks for their description, along with selected biological and artificial examples of active systems.
Analyzing the influence of geometrical deformation on photon sphere and shadow radius: A new analytical approach-stationary, and axisymmetric spacetime
Authors: Vertogradov Vitalii , Övgün Ali , Pantig Reggie C. 
Published: November 2024

Black hole shadows and photon spheres offer valuable tools for investigating black hole properties. Recent observations by the Event Horizon Telescope Collaboration have confirmed the existence of rotating black holes. Black hole parameters influence the observed shadow size. This paper aims to extend the work in [V. Vertogradov and A. Övgün, Analyzing the influence of geometrical deformation on photon sphere and shadow radius: A new analytical approach — spherically symmetric spacetimes, Phys. Dark Univ. 45 (2024) 101541] and explores the impact of geometrical deformations on black hole shadow size using gravitational decoupling to an axially symmetric spacetime. We find that the results are more complex than the spherically symmetric case. We compare shadows in the well-known models with those of a Kerr black hole. Our approach suggests that the influence of an accretion disc on the observed shadow shape can be accurately described despite negligible impact on the black hole geometry itself.
Privacy for Groups Online: Context Matters
Authors: Choksi Madiha Zahrah , Balso Ero , Kreuter Frauke , Nissenbaum Helen 
Published: November 2024

The pervasive influence of online activities in our lives, encompassing personal connections, professional engagements, and e-commerce, has amplified concerns about privacy. However, existing privacy research has predominantly concentrated on the individual level, paying less attention to the privacy practices and strategies adopted by online social groups. This research gap calls for a renewed focus on understanding and addressing privacy challenges specific to online group settings.
In this paper we explore the privacy needs of online groups through the lens of Contextual Integrity. We perform two complementary studies: semi-structured qualitative interviews of Facebook Groups users (n=17), and a large-scale survey of individuals organizing in groups on Facebook, Discord, and Reddit (n=4486). We investigate the privacy needs of different contextual groups, and locate the presence of contextual norms, contextual member roles, explicit and implicit rules, and privacy concerns. We trace how this complex interplay informs privacy expectations, needs, and negotiations across groups. We find that technical systems provide limited tools to effectively enforce group privacy, allowing individuals to compromise privacy norms. Based on these findings, we offer recommendations to support the design of privacy controls for online groups.
CUPID: Improving Battle Fairness and Position Satisfaction in Online MOBA Games with a Re-matchmaking System
Authors: Fan Ge , Zhang Chaoyun , Wang Kai , Li Yingjie , Chen Junyang , Xu Zenglin 
Published: November 2024

The multiplayer online battle arena (MOBA) genre has gained significant popularity and economic success, attracting considerable research interest within the Human-Computer Interaction community. Enhancing the gaming experience requires a deep understanding of player behavior, and a crucial aspect of MOBA games is matchmaking, which aims to assemble teams of comparable skill levels. However, existing matchmaking systems often neglect important factors such as players' position preferences and team assignment, resulting in imbalanced matches and reduced player satisfaction. To address these limitations, this paper proposes a novel framework called CUPID, which introduces a novel process called ''re-matchmaking'' to optimize team and position assignments to improve both fairness and player satisfaction. CUPID incorporates a pre-filtering step to ensure a minimum level of matchmaking quality, followed by a pre-match win-rate prediction model that evaluates the fairness of potential assignments. By simultaneously considering players' position satisfaction and game fairness, CUPID aims to provide an enhanced matchmaking experience.
Extensive experiments were conducted on two large-scale, real-world MOBA datasets to validate the effectiveness of CUPID. The results surpass all existing state-of-the-art baselines, with an average relative improvement of 7.18% in terms of win prediction accuracy. Furthermore, CUPID has been successfully deployed in a popular online MOBA game. The deployment resulted in significant improvements in match fairness and player satisfaction, as evidenced by critical Human-Computer Interaction (HCI) metrics covering usability, accessibility, and engagement, observed through A/B testing. To the best of our knowledge, Cupid is the first re-matchmaking system designed specifically for large-scale MOBA games.
"I inherently just trust that it works": Investigating Mental Models of Open-Source Libraries for Differential Privacy
Authors: Song Patrick , Sarathy Jayshree , Shoemate Michael , Vadhan Salil 
Published: November 2024

Differential privacy (DP) is a promising framework for privacy-preserving data science, but recent studies have exposed challenges in bringing this theoretical framework for privacy into practice. These tensions are particularly salient in the context of open-source software libraries for DP data analysis, which are emerging tools to help data stewards and analysts build privacy-preserving data pipelines for their applications. While there has been significant investment into such libraries, we need further inquiry into the role of these libraries in promoting understanding of and trust in DP, and in turn, the ways in which design of these open-source libraries can shed light on the challenges of creating trustworthy data infrastructures in practice.
In this study, we use qualitative methods and mental models approaches to analyze the differences between conceptual models used to design open-source DP libraries and mental models of DP held by users. Through a two-stage study design involving formative interviews with 5 developers of open-source DP libraries and user studies with 17 data analysts, we find that DP libraries often struggle to bridge the gaps between developer and user mental models. In particular, we highlight the tension DP libraries face in maintaining rigorous DP implementations and facilitating user interaction. We conclude by offering practical recommendations for further development of DP libraries.