bluuebunny/crossref_metadata_2025_split huggingface dataset:
Survivin inhibits excessive autophagy in cancer cells but does so independently of its interaction with LC3
Authors: Humphry Nicola J. , Wheatley Sally P. 
Published: October 2018

ABSTRACT
Survivin expression is pivotal to life and death at the cellular level. For the past decade its pro-survival activity has been attributed to its essential role in cell proliferation and its ability to inhibit apoptosis. However, a growing body of evidence suggests that it may also contribute to cell viability through an as yet undefined role in autophagy. We report that survivin overexpression in osteosarcoma (U2OS) cells is associated with increased LC3-II expression, smaller autophagosomes, enlarged lysosomes and reduced autophagic flux. We also demonstrate that survivin binds LC3 directly through a canonical LC3-interacting region (LIR) in its baculovirus inhibitors of apoptosis protein (IAP) repeat BIR domain, mutation of which inhibits the interaction, but does not abrogate its influence on autophagy. Collectively these data suggest that survivin expression restricts autophagic flux, thereby inhibiting late-stage autophagy and preventing cell death, but does so independently of LC3.
Case report Panuveitis: a case of suspected ocular tuberculosis
Authors: Burkes William , Freedman Kenu , Dominguez Leo 
Published: October 2018

A 32-year-old incarcerated man was evaluated for decreased vision in both eyes at a tertiary care facility. He presented with uveitis and the initial work up indicated that tuberculosis was the most likely etiology. This report will discuss the frequency, presentation, diagnostic procedures and yield, and treatment of ocular tuberculosis.
Review of inflammatory biomarkers in hospitalized adults with suspected infection
Authors: Lacy Mark 
Published: October 2018

Quantitative measurement of inflammatory biomarkers is frequently obtained in evaluating hospitalized patients with suspected or confirmed infections and other inflammatory disorders. These markers may be used to establish a diagnosis or assess response to therapy. Consensus on which marker to use and when to use them is not settled nor is the extent of how these indicators improve outcomes or quality of care. The following is a brief review of the common inflammatory biomarkers and a suggested approach for their utilization.
Development of an evacuation policy at a healthcare facility
Authors: Barry Connor , Ali Zain 
Published: October 2018

An Evacuation Policy is a procedure and plan that is needed for a healthcare facility to ensure the safety of patients, families, and the staff in the event of an Emergent or Non-Emergent Evacuation. While disasters are unplanned, a procedure of any caliber can be used to maximize resources and abilities of a healthcare facility. An Evacuation Policy is the designated policy and procedure for a partial or complete evacuation of a hospital or clinic. During an evacuation, the organization and coordination of the evacuation policy are at top priority for the successful and safe relocation of patients, families, and staff. Without an effective policy, there would be an increased risk of chaos due to uncoordinated staff and patient movement. This paper proposes an efficient evacuation plan to ensure patients are evacuated in a smooth manner on and between floors. This proposed plan is based on four fundamental principles: staff hierarchy, universal patient triaging, patient movement procedure, and end point locations. Using these four principles, an efficient flow will be created for moving patients between the affected area and the safe end point. Evacuation plans are necessary for any emergency when mass coordinated patient and staff movement to safety is required.
Quantitative Analysis of Cadmium Content in Tomato Leaves Based on Hyperspectral Image and Feature Selection
Authors: Zhang Yuechun , Sun Jun , Li Junyan , Wu Xiaohong , Dai Chunmei 
Published: October 2018

Abstract.In order to ensure that safe and healthy tomatoes can be provided to people, a method for quantitative determination of cadmium content in tomato leaves based on hyperspectral imaging technology was put forward in this study. Tomato leaves with seven cadmium stress gradients were studied. Hyperspectral images of all samples were firstly acquired by the hyperspectral imaging system, then the spectral data were extracted from the hyperspectral images. To simplify the model, three algorithms of competitive adaptive reweighted sampling (CARS), variable combination population analysis (VCPA) and bootstrapping soft shrinkage (BOSS) were used to select the feature wavelengths ranging from 431 to 962 nm. Final results showed that BOSS can improve prediction performance and greatly reduce features when compared with the other two selection methods. The BOSS model got the best accuracy in calibration and prediction with R2c of 0.9907 and RMSEC of 0.4257mg/kg, R2p of 0.9821, and RMSEP of 0.6461 mg/kg. Hence, the method of hyperspectral technology combined with the BOSS feature selection is feasible for detecting the cadmium content of tomato leaves, which can potentially provide a new method and thought for cadmium content detection of other crops. Keywords: Feature selection, Hyperspectral image technology, Non-destructive analysis, Regression model, Tomato leaves.
Design, Testing, and Evaluation of a Hydrous Bioethanol Distiller for the Production of Fuel-grade Alcohol from Nipa Sap (Nypa fruticans)
Authors: Regalado Manuel Jose Cajayon , Belonio Alexis Tanangonan , Villota Katherine Corpuz , Rafael Marvelin Legaspi , Castillo Phoebe Reyes 
Published: October 2018

Abstract.To help reduce dependence on fossil fuels for mechanized farm operations, we developed and tested a distiller using fermented nipa sap with 7% alcohol content and diluted nipa sap fermentation liquor or crude bioethanol (15% concentration) to produce fuel-grade bioethanol for small spark-ignition engines. Keywords: Click here to enter keywords and key phrases, separated by commas, with a period at the end
Utilization of Araceae by local community in Cisoka Village, Cikijing Sub-district, Majalengka District, West Java, Indonesia
Authors: MUTAQIN ASEP ZAINAL , FATHARANI MUTHI , ISKANDAR JOHAN , PARTASASMITA RUHYAT 
Published: October 2018

Mutaqin AZ, Fatharani M, Iskandar J, Partasasmita R. 2018. Utilization of Araceae by local community in Cisoka Village, Cikijing Sub-district, Majalengka District, West Java, Indonesia. Biodiversitas 19: 640-651. Various species of Araceae plants are widely used by the tribes of Sunda as food. However, cultivation is increasingly rare inWest Java region, and is found in some places only. One area where many people still grow Araceae plants is Cisoka Village, Cikijing Sub-district, Majalengka District, West Java Province, Indonesia. This paper aims to explain the reason for the cultivation of Araceae by the local community in the Village of Cisoka. This study used a combination of qualitative and quantitative methods, but the former was used more than the latter The primary data were collected through structured and semi-structured interviews, participant observation, exploration, and plant sample collection. The data were analyzed descriptively with emic and ethic approaches. The results of the study showed that 20 species and 13 varieties (landraces) of Araceae plants were used by the community. The parts of plant traditionally used by the commumity were tuber, petiole, and leaf. The utilization of the Araceae plants were categorized into 4 main functions, namely, as food, medicine, decoration, and fish feed. The species of Araceae were commonly cultivated in various agroecosystem types, mainly home gardens, gardens, and rice fields.
Novel Single Nucleotide Polymorphisms in the Sumba Ongole (Bos indicus) Growth Hormone Gene
Authors: AGUNG PASKAH PARTOGI , PUTRA WIDYA PINTAKA BAYU , ANWAR SAIFUL , WULANDARI ARI SULISTYO , SAID SYAHRUDDIN , ZEIN MOCH SYAMSUL ARIFIN , SUDIRO ADITYA 
Published: October 2018

Agung PP, Putra WPB, Anwar S, Wulandari AS, Zein MSA, Said S, Sudiro A. 2018. Novel Single Nucleotide Polymorphisms in the Sumba Ongole (Bos indicus) Growth Hormone Gene. Biodiversitas 19: 676-681. The Sumba Ongole cattle (Bos indicus) is one of the local Indonesian cattle breeds and has excellent potential to gain higher carcass yield compared to other local cattle breeds in Indonesia. The Growth Hormone (GH) gene was a potential target for molecular study due to its importance as growth regulating hormone. This study was aimed to determine Single Nucleotide Polymorphism (SNP) profile of the GH gene in the Sumba Ongole (SO) cattle using PCR and DNA sequencing methods from 34 individual DNA samples. The results from this study showed that there are 28 SNPs identified within the GH gene; Twenty one SNPs were found to occur in the intron region, 4 SNPs in the exon region, and 3 SNPs in the 3’ end region. There were 17 SNPs in the SO cattle GH gene were caused by novel mutation. The novel SNP g.1395insC was found only in the SO cattle. Moreover, the frequency of the SNP g.1395insC was the highest among other novel SNPs in the SO cattle GH gene. The moderate PIC value (0.25<PIC<0.50) were found in two novel SNPs i.e. SNP g.1415C>G (intron 4), and SNP g.1526A>G (intron 4). The GH gene in the SO cattle was polymorphic and the 17 novel SNPs need to be further validated.
Short Communication: Cave-dwelling Arthropod community of Semedi Show Cave in Gunungsewu Karst Area, Pacitan, East Java, Indonesia
Authors: KURNIAWAN ISMA DWI , RAHMADI CAHYO , CARAKA REZZY EKO , ARDI TIARA E. 
Published: October 2018

Kurniawan ID, Rahmadi C, Caraka RE, Ardi TE. 2018. Short Communication: Cave-dwelling Arthropod community of Semedi Show Cave in Gunungsewu Karst Area, Pacitan, East Java, Indonesia. Biodiversitas 19: 857-866. Arthropods are a major group of animals which have significant roles in maintaining cave ecosystem stability. Semedi is a new show cave, but information about arthropods in this cave was not available. The use of cave as a tourist attraction will bring environmental changes which potentially disturb cave-dwelling arthropod community. This study aimed to measure arthropod diversity and their relation to abiotic factors in Semedi Show Cave. Arthropods were sampled by hand collecting, a combination of pitfall and bait traps, and Berlese extractor. Abiotic factors measured were climatic and edaphic parameters. Sampling was conducted in the 3 zones of Semedi cave (Entrance, Twilight, and Dark). Data were analyzed by calculation of richness (Margalef), diversity and evenness (Shannon-Wiener) indices, cluster and correlation analyses. A total 1095 individuals of arthropods consisting of 102 morphospecies, belonging to 6 Classes, and 19 Orders were sampled during this study. The entrance zone had higher richness and diversity indices (richness=12.80, diversity=3.40) than the twilight zone (richness=7.85, diversity=3.25) and the dark zone (richness=5.35, diversity=2.63). Meanwhile, the twilight zone had higher evenness index (0.85) than the entrance zone (0.77) and the dark zone (0.77). Each zone of Semedi cave had different abiotic conditions. Abiotic conditions and Arthropod communities in the twilight and dark zones were more similar to each other than to those of the entrance zone. The statistical analyses showed that there were significant correlations between abiotic factors and arthropod communities. Semedi had various cave-dwelling arthropods. Sustainable management of show cave should be applied to minimize the destructive impact of tourism activities on the cave arthropod community.
Conservation and selection of plus trees of Pongamia pinnata in Bali, Indonesia
Authors: ARPIWI NI LUH , WAHYUNI I GUSTI AYU SUGI , MUKSIN I KETUT , SUTOMO SUTOMO 
Published: October 2018

Arpiwi NL, Wahyuni IGAS, Muksin IK, Sutomo. 2018. Conservation and selection of plus trees of Pongamia pinnata in Bali, Indonesia. Biodiversitas 19: 1607-1614. Pongamia pinnata (L.) Pierre or commonly known as pongamia is a tropical legume tree produces oil seeds for biodiesel feedstock. The aims of present study were mapping growth sites of pongamia in Bali, counting the number of trees and selecting plus trees based on growth parameters such as total height, clear bole height, diameter at breast height, canopy width, and oil content. Method of plus tree selection was comparison tree where one candidate tree was compared with 5 nearby check trees from each village. A total of 126 pongamia trees were found in coastal beach of Bali. The majority of trees were in the north west of the island. Temperature ranges from 26-28oC, humidity ranges from 74-80% and altitude 5-50 meters above sea level. Eight pongamia plus trees were selected from 4 villages namely Kalibukbuk, Pengulon, Pemogan, and Sanur. In conclusion, pongamia was mostly distributed in the northern-west part of the Bali Island of Buleleng District. Lower number of trees was also found in the southern and western part of the island. Trees either scattered or grown in small groups. The number of pongamia tree in Bali is small and this needs further action for conserving the species.
Spatial distribution of echinoderms in littoral area of Ambon Island, Eastern Indonesia
Authors: SETYASTUTI ANA , PURBIANTORO WAHYU , HADIYANTO HADIYANTO 
Published: October 2018

Setyastuti A, Purbiantoro W, Hadiyanto. 2018. Spatial distribution of echinoderms in littoral area of Ambon Island, Eastern Indonesia. Biodiversitas 19: 1919-1925. Echinoderms samples were collected in Ambon Island as part of the marine resource inventories designed to study the biodiversity of Maluku Archipelago. The purpose of this works was to investigate the abundance and genus richness of echinoderms within the five sampling sites using single transect orthogonal to the coast consisted of 10-quadrat plot of 5x5m, the distance between plots was 10m at each site. Furthermore, this study also aimed to understand the relation of substrate type and community composition within those five sites. The substrate was classified into four types (sea-grass, macro-algae, sand, rocks and/or dead coral) noted by presence/absence mark at each plot. The differences in total abundance and genus richness among those sites were analyzed using an Analysis of Deviance following a Generalized Linear Models (GLMs) fitted by Poisson and log link. However, in term of genus composition, the data were visualized using a Principal Coordination Analysis (PCoA) plots calculated from Bray-Curtis dissimilarity based on the log (x+1) transformed abundance data. A total of 910 individuals of echinoderms belonging to 19 genera was successfully recorded. Total abundance of echinoderms was different significantly among sites (p<0.05). The most abundant echinoderms were collected from Tanjung Tiram, approximately 68.71 individuals/quadrat, which was almost 1.4 times than those in Liang and even 4 times than those in Suli. The genus composition between sites was significantly different (p<0.05). The composition of substrate types among sites was not significantly different (p>0.05), however the composition of substrates correlated significantly with the composition of echinoderms genus (p<0.05, rho=0.36). In conclusion, more complex the substrate variation in an area will affect the diversity and abundance of Echinoderms community therein.
Study on Dimension Measurement for Gas Guide Groove of Gun Barrel
Authors: Liu Xiaofeng , Yang Kangjun , Bo Lin 
Published: October 2018

Abstract
An automatic measurement system based on the stationary wavelet transform (SWT) of vibration signal is developed to obtain the depth and width of gas guide grooves in the gun barrel. The system consists of the programmable logic controller module used to control the motions of system components, a mechanical apparatus used to fix the gun barrel and position the transducer, and a measurement device used to capture and analyze the measured data. With the SWT, the interference noise, baseline wander, and interference harmonics are successively eliminated from the captured displacement signal. Afterwards, the peak and valley points are detected out, which, respectively, represent the information of groove depth and of groove width. Finally, the dimensions of the gas guide groove are determined according to the points detected out and the calibration information. In the experiment, the steps of data processing are provided in detail, and the analysis results show that the measuring error is less than 3 %, which can meet the actual requirements.
Experimental and 3-D Finite Element Analyses on Geocell-Reinforced Embankments
Authors: Banerjee Lalima , Chawla Sowmiya , Bhandari Gupinath 
Published: October 2018

Abstract
This article presents an improvement in performance that is due to the inclusion of geocell in the embankment base overlying a soft foundation bed. Firstly, model tests were conducted on embankments over soft clay, in which a mattress of geocell reinforcement was placed at the interface between the embankment and soft foundation bed, which was trimmed at the embankment’s toe. Parameters like type of infill material and aspect ratio (pocket-size) of the geocell layer were varied during the experimental program to observe their effects on the performance of geocell-reinforced embankments. A model test on unreinforced embankment was also carried out to show influence on performance and improvement as a result of the presence of geocell reinforcement. A significant percentage of decrease in vertical settlements, lateral deformations, and heaving—with a percentage of increase in the load-bearing capacity of embankments reinforced with geocell—were observed from the test results, as compared to unreinforced embankments. The experimental results were validated using three-dimensional finite element analyses of geocell-reinforced embankments. The results of the finite element method (FEM) showed good agreement with that of the model tests. The displacement and vertical stress distributions of geocell-reinforced embankment were also studied using FEM. Lastly, a parametric study was carried out to observe the influence of the stiffness of subgrade soil, tensile strength of geocell material, stiffness of infill material, effective friction angle of infill material, and effective cohesion of embankment soil on the performance of geocell-reinforced embankment base.
Improved Approach for Determining Pile Length of Group Pile Using Complex Continuous Wavelet Transform
Authors: Ni Sheng-Huoo , Tsai Pei-Hsun , Yang Yu-Zhang , Chou Wei-Hsiang 
Published: October 2018

Abstract
This article investigates the integrity testing ability of the sonic echo test by using a field-constructed group pile foundation. The energy of the reflected stress wave is relatively weak when a pile cap is presented during pile testing, and signal processing techniques were generally used to enhance the weak signal. The conventional real wavelet transform is difficult to use to identify the time of the reflected wave of the pile toe. The purpose of this article is to improve this drawback of conventional real wavelet transforms using a complex wavelet transform. This study utilized the amplitude and phase message of a complex continuous wavelet transform to determine the pile length of piles that are grouped with a pile cap by analyzing the time-frequency-phase angle diagram in the wide frequency band. Cases of group piles with two and four piles were studied. The results show that the suggested approach is able to detect the reflected signal from the pile toe, as the testing was performed on a pile cap. The results also show that the measured errors of pile length ranged from 2.5 % to −6.1 % in the cases of this study.
Bone Glue Modified Fuel Resistant Asphalt Binder
Authors: Rizvi Hashim Raza , Mehta Yusuf , Weis Darren , Purdy Caitlin 
Published: October 2018

Abstract
Fuel resistant asphalt (FRA) is the binder that can delay hydrocarbon fuel damage by resisting the cut-back properties of hydrocarbon fuels such as gasoline, kerosene, etc. The high solubility of asphalt binder in hydrocarbon fuels results in pavement damage that is due to fuel/oil spills at airports, parking lots, drive ways, and roads. FRA can effectively be used to minimize the damage caused by hydrocarbon fuels and improve overall performance of the pavement structure. The additives/composition used in the past to develop FRA were not fully disclosed by the inventors. This research study focused on developing FRA for commercial use using a biopolymer as an additive. Fuel resistance testing, along with mechanical performance testing, was used to evaluate the fuel resistance capabilities and performance of modified binder. Furthermore, a conventional styrene butadiene styrene modified binder was used to compare the fuel damage resistance capabilities and performance characteristics of bio versus synthetic polymer-modified binders. The biopolymer not only significantly enhanced the fuel damage resistance of the neat binder but also improved mechanical properties of the neat binder. Biopolymer-modified asphalt binder showed improvement in rut resistance, elastic response, and performance grade at intermediate and high temperatures.
Numerical Modeling of Roadway Embankment Construction Over Existing Sewers
Authors: Cao Laifa , Peaker Scott 
Published: October 2018

Abstract
This article presents a case study of the influence of a roadway embankment on existing sewers with a diameter or width in the range of 3.3 to 4.3 m using numerical modeling. The proposed embankment would be constructed directly above the existing sewers, which would induce an additional load on the sewers. Traditional analysis methods cannot account for the soil–structure interaction and the benefit of the lateral supporting characteristics of the soils. In order to evaluate the loading of the proposed embankment on the existing sewers, a soil–structure interaction analysis using a two-dimensional finite element analysis was performed for various loading cases. The sensitivity of soil parameters was also studied in the analysis. From the analysis, the loads on the sewers, including axial force, bending moment and shear force, were obtained, and then the structural capacity of the existing sewers was checked. Lightweight sand fill or expanded polystyrene (EPS) geofoam was considered to reduce the additional vertical and horizontal loads on the sewers. The EPS geofoam or a structural protection system consisting of a concrete slab supported by concrete piles was proposed to eliminate any incremental vertical and horizontal loads on the sewers. Findings from the analysis concluded that the lightweight sand fill was the most economical material for reducing the additional loads on the sewers, EPS geofoam was the most suitable material to eliminate incremental loading on the sewers for a lower embankment, and the structural protection system was necessary to eliminate the incremental loads on the sewers for a higher embankment.