bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the presence of human anti-mouse antibodies (HAMA) in the blood of laboratory animal care workers
Authors: Mohammadi Mohammad Mahdi , Bozorgi Shahram 
Published: March 2019

Abstract

Background
In the present study, the researchers evaluated the presence of human anti-mouse antibodies (HAMA) in a normal population and laboratory animal care providers for the first time in the world. Also, the cause of HAMA incidence in the human body through a close contact with mice was identified.

Methods
The study population consisted of 40 laboratory animal care providers aged between 24 and 57 years with a close contact with mice (e.g. taking care of mice, feeding mice, etc.) and 40 individuals of the same age as the above group with no contact with mice. HAMA was measured in both the case and control groups using sandwich enzyme-linked immunosorbent assay (ELISA) method. Data were analyzed using SPSS 18. Univariate and multivariate linear regression and independent t-test were used. The significance of results was measured based on p < 0.05.

Results
The present study revealed that the animal care providers had (p = 000) a higher titer of HAMA (4.95 ng/mL) in their blood than the control group (1.67 ng/mL). Also, the individuals in the case group (exposed to mice) were more allergic (43.6%) than those in the control group (15%) (p = 0.003).

Conclusions
The results of this study revealed that exposure to mice in laboratory care centers can cause production of HAMA in the human body but its titer is possibly lower in Iranian working staff than those in the other parts of the world.
Emissions Trading Hybrids: The Case of the EU ETS
Authors: Woerdman Edwin , Nentjes Andries 
Published: March 2019

AbstractWe argue that the European Union Emissions Trading System (EU ETS) has evolved into a hybrid of two design variants, allowance trading (cap-and-trade) and credit trading (performance standard rate trading), with an added feature of industry support to minimize carbon leakage. In particular the current rules tying free allowances to production capacity expansion, plant closure and capacity use have transformed the efficient cap-and-trade program that stood at the origins of the EU ETS into a system that even surpasses credit trading in paying hidden product subsidies to firms. This combination of rules encourages an inefficiently high level of investment in production capacity and an inefficiently high output in industries exposed to international competition. The result is a sub-optimal EU Emissions Trading ‘Hybrid’ (which we therefore label as ‘EU ETH’).
Is the Simple Price Premium that Simple?
Authors: Shi Yuying 
Published: March 2019

Abstract
Brand equity has been a perennial topic in marketing. Among all types of measures, price premium is widely accepted due to its simple yet efficient characteristics. However, there is some disagreement regarding whether this measure captures enough facets of brand equity and whether price premium is an appropriate measure to reflect the market position of a brand. With current technique developments, more sophisticated brand equity measures have been developed. A natural question arises as to whether more sophisticated measures are better than price premium. Using large-scale national scanner data covering 47 major U.S. markets, we employ the aggregated demand model to estimate a complex brand equity measure and compare it with price premium. Our results suggest that the simple price premium is consistent with the complex measure under certain conditions. We provide managers with suggestions regarding choosing the most appropriate brand equity measures to signify their brands’ values.
God of the Nations: Daniel, Satan, and the Temptation of Jesus in Luke
Authors: Ferda Tucker S. 
Published: March 2019

Abstract
In both Matthew and Luke, Satan offers Jesus “all the kingdoms of the world” in exchange for his obeisance. Only in Luke, however, does Satan make an intriguing claim about his “authority” over the kingdoms and his prerogative to “give” such “to whomever he wishes” (4:6). Richard Hays lamented in his recent Echoes of Scripture in the Gospels that this unique detail has not been given thorough attention in exegetical studies of Luke-Acts. This study takes up the question of Satan’s claim in detail and suggests that Satan’s words are informed by a phrase that appears multiple times in the book of Daniel: “the Most High is sovereign over the kingdom of mortals and gives it to whomever he wishes.” This intertextuality is important for the larger narrative of Luke-Acts in two respects. First, it presses the question of whether, from the perspective of the larger narrative, Satan’s claim is truthful. The article concludes that an answer to that question is not immediately clear; the narrative permits varied readings. Secondly, it is argued that the Danielic background of Luke 4:6 intensifies the Christological drama of the narrative. Jesus is here tested with what is legitimately his as Daniel’s “Son of Man,” and we soon find that he will receive such not from the hand of Satan but from obedience to God.
Verstehen und Glauben im Johannesevangelium: Ein alternativer Übersetzungsvorschlag für Joh 5,37–40
Authors: Förster Hans 
Published: March 2019

Abstract
John 5:37–40 concerns a central problem of the Gospel of John: the relationship between understanding and faith. Translational choices appear to have had a strong influence on the interpretation of this passage. This contribution discusses alternative options for translating the passage. This alternative understanding of the passage allows the author to argue in favour of close links between John 5:37–40 and Jewish tradition.
THE TRACEABILITY OF MATERIALS IN A BRAZILIAN PUBLIC HOSPITAL
Authors: Santos Mateus , Reis Augusto Cunha , Dias Ana Claudia , Senna Pedro , Pizetta Luciane Machado 
Published: March 2019

In Brazil all citizens has free access to public health. Currently the number of people using this service presented an extraordinary growth due to the economic crisis taking in the country that culminated in the incapacity of them in to maintain health insurance. At Rio de Janeiro there is a constant concern regarding the quality of the services offered to the population. In this way, a case of study was elaborated in a federal hospital, located at Rio de Janeiro, with the purpose to present the problems faced by the hospital related to the traceability and management of materials in warehouse. It believes that any economy resulting from the improvements of warehouse management should provide a gain to the services offered to the population. The result of the study was the elaboration of a proposal to be implemented by the hospital, in order to mitigate problems faced by them that impacts the reduction of costs and improvement of the services.
Mentally tiring work and type 2 diabetes in women: a 22-year follow-up study
Authors: Fagherazzi Guy , Gusto Gaelle , El Fatouhi Douae , Mancini Francesca Romana , Balkau Beverley , Boutron-Ruault Marie-Christine , Bonnet Fabrice 
Published: March 2019

Hypothesis
Previous work suggested no or inconsistent associations between components of work-related stress and type 2 diabetes risk, but suggested sex-specific differences should be further investigated, as women potentially had higher risks.

Methods
We analyzed data from 73 517 women, mostly teachers, from the E3N cohort study followed for 22 years (1992–2014), to study the association between mentally tiring work, used as a proxy of job demands, and type 2 diabetes risk. Univariate and multivariable Cox regression models were used to estimate hazard ratios and 95% confidence intervals.

Results
A total of 4187 incident cases of type 2 diabetes cases were observed. There was a higher type 2 diabetes risk for women with a ‘Very mentally tiring work’ when compared to women with ‘Little or not mentally tiring work’ (HR = 1.21 (1.09–1.35)). This association was independent of unhealthy lifestyle and traditional metabolic factors. An interaction between mentally tiring work and BMI was detected (P < 0.0001), with a stronger association being observed in non-overweight women, HR = 1.26 (1.08–1.47) vs HR = 1.14 (0.98, 1.32), in overweight women.

Conclusions
We observed an increased risk of type 2 diabetes associated with mentally tiring work, used as a proxy of job demands. These observational results suggest the importance of taking into consideration the potential long-term metabolic impact of work-related stress for women working in a demanding environment. Increased support for such women should be investigated in intervention studies.
Cine, poder e historia: la representación y construcción social del indígena en el cine ficción venezolano durante la década de los años 80
Authors: Rodríguez Velásquez Fidel 
Published: March 2019

El presente artículo analiza desde una perspectiva histórico-antropológica al cine como vehículo en el que se relacionan de forma directa o indirecta el poder (estatal) y la historia (historia oficial) en la representación del indígena venezolano durante la década de los años 80, utilizando la noción de historia de Gaskell (1996) quien la entiende como “el discurso elaborado por los historiadores y no el pasado”, y lo señalado por Iglesias (2013) cuando esboza que “el cine tiene un papel político crucial como mediador del imaginario colectivo a la hora de construir identidades”, para ello se realizó un análisis crítico del discurso que sobre los pueblos indígenas venezolanos están contenidos en las películas: Caballo Salvage (1981), Orinoko Nuevo Mundo (1984), Ya-koo (1985), Cubagua (1987) y Amérika, terra incógnita (1988) a la luz de las ideas que de estos se impulsaron desde el Estado Venezolano.
Locating and Characterizing a Transgene Integration Site by Nanopore Sequencing
Authors: Nicholls Peter K , Bellott Daniel W , Cho Ting-Jan , Pyntikova Tatyana , Page David C 
Published: March 2019

AbstractThe introduction of foreign DNA into cells and organisms has facilitated much of modern biological research, and it promises to become equally important in clinical practice. Locating sites of foreign DNA incorporation in mammalian genomes has proven burdensome, so the genomic location of most transgenes remains unknown. To address this challenge, we applied nanopore sequencing in search of the site of integration of Tg(Pou5f1-EGFP)2Mnn (also known as Oct4:EGFP), a widely used fluorescent reporter in mouse germ line research. Using this nanopore-based approach, we identified the site of Oct4:EGFP transgene integration near the telomere of Chromosome 9. This methodology simultaneously yielded an estimate of transgene copy number, provided direct evidence of transgene inversions, revealed contaminating E. coli genomic DNA within the transgene array, validated the integrity of neighboring genes, and enabled definitive genotyping. We suggest that such an approach provides a rapid, cost-effective method for identifying and analyzing transgene integration sites.
A tudás útja: A másolattól az eredetiig a Budapest Székesfovárosi iparrajziskola (1886–1945) egykori gipszgyűjteményének kutatása
Authors: Katona Júlia 
Published: March 2019

The paper presents the conception and art historical conclusions of the exhibition entitled Knowledge in Plaster Casts. The former cast collection of the Budapest Metropolitan Industrial Drawing School (1886–1945) held in FUGA Budapest Center of Architecture on 4–25 October 2017.
The three groups of exhibits comprised original 19–20th century plaster casts, 18–19th century drawings from casts, and reproduced photos from the catalogue of the casting workshop of the Hungarian National Royal Higher School of Architecture dated 1904. As the price list illustrations revealed, late 19th–early 20th century cast collections for the purpose of education were visual encyclopaedias of the educational and cultural ideals of the age. Thematically, the replicas of pattern and sculpture conveyed a broad scale of mythological knowledge, culture historical information via notable figures of literature and history, as well as botanic, anatomical and geometric knowledge. The compilation of a cast collection required broad historical, culture historical and professional expertise, and the casting workshops and the cast catalogues they published mediated this common knowledge.
The exhibition and the preceding elaboration of the collection provided further art historical conclusions, of which the paper embarks on the relationship between original and copy apropos a plaster paraphrase of a 12th century stone carving from Saint Denis.
Lean Start-Up as a Strategy for the Development and Management of Dynamic Entrepreneurships
Authors: Araya Castillo Luis 
Published: March 2019

In recent years, several methodologies have emerged for the development and management of enterprises and new enterprises. One of the methodologies with the greatest impact in the global entrepreneurial community in the creation of the launch, developed by Erick Ries in 2008. This is based on the principles of scientific method and artistic creation. In this scenario, the objective of the present investigation is to analyze the methodology of Lean Initiation as a process of management and development of enterprises, mainly states as dynamic. In addition, a brief comparative analysis with other similar methodologies will be carried out in such a way that it is possible to objectively justify the use of this method. ResumenEn los últimos años han surgido una serie de metodologías para el desarrollo y la gestión de emprendimientos y nuevas empresas. Una de las metodologías con mayor impacto en la comunidad emprendedora global es la del Lean Start-up, desarrollada por Erick Ries en el año 2008.Ésta se fundamenta en los principios del método científico y de la creación artística. En este escenario, el objetivo de la presente investigación es el de analizar la metodología del Lean Startup como proceso de gestión y desarrollo de emprendimientos, principalmente aquellos clasificados como dinámicos. Además, se realizará un breve análisis comparativo con otras metodologías similares de forma tal que sea posible justificar objetivamente la utilización de este método. ResumoNos últimos anos, vários métodos surgiram para o desenvolvimento e gestão de empresas e novas empresas. Um dos métodos com maior impacto na comunidade empreendedora global na criação do lançamento, desenvolvido por Erick Ries em 2008. Isto é baseado nos princípios do método científico e da criação artística. Neste cenário, o objetivo da presente investigação é analisar a metodologia de Lean Initiation como um processo de gestão e desenvolvimento de empresas, principalmente estados como dinâmicos. Além disso, uma análise comparativa com outras metodologias similares será realizada de tal forma que seja possível justificar objetivamente o uso desse método.
Leptomeningeal Carcinomatosis in Chronic Lymphocytic Leukemia: A Case Report and Review of the Literature
Authors: Naydenov Alipi V. , Taylor Lynne P. 
Published: March 2019

AbstractLeptomeningeal disease is a rare complication of chronic lymphocytic leukemia (CLL). We report a case of leptomeningeal disease in CLL with a complete clinical response and clearance of cerebral spinal fluid (CSF) after treatment with ibrutinib and intrathecal rituximab. In a comprehensive review of the published literature since 1976, we found 136 cases of CLL with leptomeningeal spread. We found that leptomeningeal disease in patients with CLL responds favorably to treatment in most cases and is associated with longer overall survival than is expected for other cancers. Clearance of CSF is associated with improved survival. Treatment with rituximab and ibrutinib is more frequently associated with complete response compared with older agents.Implications for PracticeThe incidence of leptomeningeal CLL is more common than previously described and can be recognized by attention to certain symptoms and signs. This case presentation and literature review reveals that, in many cases, leptomeningeal lymphomatosis is reversible with the use of rituximab and ibrutinib. The authors show a survival benefit associated with treating to cerebral spinal fluid (CSF) clearance by cytology and compare outcomes with various treatment strategies, focusing on novel agents. Now that there is effective therapy for leptomeningeal lymphoma in CLL, the importance for oncologists to recognize this neurologic complication has become clear.
Comprehensive study of salivary gland neoplasms: single department study in a tertiary care centre
Authors: Muthuchitra S. , Saravanaselvan V. , Malarvizhi R. 
Published: March 2019

<p class="abstract"><strong>Background:</strong> Pathologies of salivary glands are common in the general population. Of them few are neoplasms-benign or malignant. The presentation of salivary gland pathologies are both to general surgeons and otorhinolaryngologists of the same hospital. The presentation to concerned treating surgeon is based on the symptoms during presentation. This study aims at the various types of salivary gland pathologies requiring surgical intervention and the rate of recurrence following surgery in a single department.</p><p class="abstract"><strong>Methods:</strong> Retrospective study was conducted. Study period was from May 2017 to February 2019. All salivary gland neoplasms were studied for presentation and recurrence following surgery. </p><p class="abstract"><strong>Results:</strong> Intraoperative difficulties and post-operative complications more common in malignant tumors. Female gender is more commonly affected by benign neoplasms. There is no gender predilection in malignant neoplasms. Facial nerve is most common nerve to get affected in pre-operative and during surgery as well.</p><p class="abstract"><strong>Conclusions:</strong> Neoplasms of salivary glands are common in females though it has equal incidence in malignancy. Facial nerve is most commonly affected as complication in malignant neoplasms.</p>
Spatial and Temporal Variations of PM2.5 Concentration and Air Quality in Isfahan City in 2016
Authors: Jadidi Hossein , Shahsavani Abbas , Mahaki Behzad 
Published: March 2019

Introduction: Particular Mineral (PM) less than 2.5 (PM2.5) is considered as one of the most important pollutants with major health effects. Therefore, the aim of this study was to evaluate spatial and temporal variations of PM2.5 concentrate and air quality in Isfahan city in 2016.
Materials and Methods: In this cross-sectional study, spatial and temporal changes in PM2.5 concentrations were evaluated. The concentrations of PM2.5 in 6 stations in Isfahan were measured. Data were analyzed using Excel and SPSS software.
Results: The results of the study showed that PM2.5 concentrations were higher in warm months than in cold months, and also in the early days of the week's PM2.5 concentrations were higher than the weekends. The total average of concentration of PM2.5 in Isfahan was 29.87 ± 10.9 μg/m3. City of Isfahan was healthy for 296 days and was in an unhealthy condition for 70 days. Furthermore, concentration of PM2.5 was higher in the central parts of Isfahan.
Conclusion: The present study showed that in most days and months of the year, the concentration of PM2.5 in Isfahan was higher than the standard limit of World Health Organization (25 μg/m3), and PM2.5 concentrations mean in the cold season was higher than the hot season. It seems that the growth, control and the management of this pollutant is essential for citizens' health and reduction of unhealthy effects.
Evaluation of Point-of-Use Drinking Water Treatment Systems Efficiency in Reducing or Removing Physicochemical Parameters and Heavy Metals
Authors: Pourjamali Raziyeh , Khalili Sadrabad Elham , Hashemi Sayed Aliasghar , Shekofteh Hosein , Mokhtari Mehdi , Heydari Ali , Akrami Mohajeri Fateme 
Published: March 2019

Introduction: Nowadays, many people have bought and installed home water treatment devices (point-of-use drinking water treatment systems), as an essential measure, to improve their health.
Materials and Methods: This cross-sectional study was conducted to evaluate the parameters of drinking water of Rafsanjan city and home water treatment device in summer 2017. Water samples at the inlet and outlet of the device with 15 day intervals for three months (approximately 48 samples, summer) were collected. Then, the concentration of heavy metals, total hardness, EC, sodium and nitrate were measured in inlet and outlet of treatment devices. All data were statistically analyzed by SPSS software version 18.
Results: The results showed that in the inlet water, the EC and pH values were in the standard ranges. The concentrations ​​of arsenic was higher than the permissible limits and other parameters including total hardness, calcium, sodium, magnesium, nitrate, copper, zinc and lead were lower than the standard limits. The highest reduction efficiency was obtained for copper, zinc and arsenic respectively, and the lowest reduction efficiency was reported for nitrate and calcium.
Conclusion: Therefore, it can be concluded the devices could reduce the concentrations of the parameters under the standard limits. Due to the relationship between heart disease and light water, it is suggested that, in view of the high arsenic content in Rafsanjan water, filters at the inlet municipal water can be used to absorb heavy metals, especially arsenic.
Mothers' Voices Related to Caregiving: The Transition of a Technology-Dependent Infant from the NICU to Home
Authors: Toly Valerie Boebel , Blanchette Julia E. , Alhamed Arwa , Musil Carol M. 
Published: March 2019

PurposeThe transition from the NICU to home is a complicated, challenging process for mothers of infants dependent on lifesaving medical technology, such as feeding tubes, supplemental oxygen, tracheostomies, and mechanical ventilation. The study purpose was to explore how these mothers perceive their transition experiences just prior to and during the first three months after initial NICU discharge.DesignA qualitative, descriptive, longitudinal design was employed.SampleNineteen mothers of infants dependent on lifesaving technology were recruited from a large Midwest NICU.Main Outcome VariableDescription of mothers' transition experience.ResultsThree themes were identified pretransition: negative emotions, positive cognitive-behavioral efforts, and preparation for life at home. Two posttransition themes were negative and positive transition experiences. Throughout the transition, the mothers expressed heightened anxiety, fear, and stress about life-threatening situations that did not abate over time despite the discharge education received.
Delayed-Onset Interface Fluid Syndrome After LASIK Following Phacotrabeculectomy
Authors: Kim Chung Young , Jung Young Ho , Lee Eun Ji , Hyon Joon Young , Park Kyu Hyung , Kim Tae Woo 
Published: March 2019

Abstract
Background
Interface fluid syndrome (IFS) is an unusual complication after laser-assisted in-situ keratomileusis (LASIK). We report the first case of IFS after uncomplicated phacotrabeculectomy in a patient who had undergone LASIK 10 years previously. This case emphasizes the importance of intraocular pressure (IOP) interpretation in eyes that have undergone LASIK.

Case presentation
A 30-year-old woman with a history of LASIK surgery presented to glaucoma clinic due to uncontrolled IOP despite of maximally tolerable medical treatment. After receiving phacotrabeculectomy, IOP decreased to 3mmHg on the first postoperative day, but again increased up to 21mmHg and a diffuse corneal edema with cloudy flap interface was demonstrated by slit-lamp microscopy. Corneal edema was sustained even after the IOP was lowered to 14 mmHg. Spectral-domain optical coherence tomography scanning of the cornea revealed a diffuse, thin fluid pocket in the corneal interface. After laser lysis of the scleral flap sutures, IOP was further decreased to 9mmHg and interface fluid was resolved.

Conclusion
IFS should be considered as a possible cause of postoperative corneal edema despite of low IOP in the eyes that underwent LASIK surgery. Additional IOP lowering may be helpful for resolving the corneal edema.