bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validación de un instrumento de evaluación del comportamiento sexual de personas con discapacidad intelectual para padres (ECS-PA)
Authors: Gil-Llario M. D. , Elipe-Miravet M. , Giménez-García C. , Bisquert-Bover M. , Castro-Calvo J. 
Published: September 2019

La reciente normalización de la sexualidad y de los derechos sexuales entre las personas conDiscapacidad Intelectual (DI) ha hecho que se incremente el número de iniciativas dirigidas a mejorar sus conocimientos y habilidades mediante programas de educación afectivo-sexual pero dichos programas requieren instrumentos de evaluación fiables que permitan identificar sus necesidades y puedan ser sensibles al cambio tras la intervención. En dicha valoración deben confluir sus percepciones, las de los profesionales que se ocupan de ellos y las de sus padres para asegurar la veracidad de la información obtenida, pero lamentablemente carecemos de instrumentos psicométricos válidos y fiables tanto autoinformados, debido a que en muchos casos carecen de habilidades verbales suficientes para expresar sus deseos y vivencias, como heteroinformados, pues los existentes se centran fundamentalmente en el estudio de las actitudes hacia la sexualidad de este colectivo. El objetivo de este trabajo ha sido construir y validar un cuestionario para obtener información de los padres acerca de la sexualidad de las personas con DI leve o moderada. El instrumento fue administrado a 118 padres de personas adultas con DI. Se realizó un Análisis Factorial Exploratorio seguido de un Análisis Factorial Confirmatorio que ofreció una estructura compuesta de 3 factores: (F1) Comprensión de la privacidad y normas sociales (13 ítems), (F2) percepción de los conocimientos sobre sexualidad que tiene su hijo/a (10 ítems), y (F3) preocupación por un comportamiento sexual inadecuado (9 ítems). El modelo obtenido con estos tres factores presenta un buen ajuste como muestran los principales indicadores (Chi2 S-B/df = 1,14, RMSEA = 0,035, CFI = 0,910 y TLI = 0,902). El ECS-PA se muestra como un instrumento que permite obtener información válida y fiable sobre la sexualidad de las personas con DI leve o moderada.
Ten Native Tree Species for potential use in Soil Bioengineering in northeastern Mexico
Authors: Zavala González Rebeca , Cantú-Silva Israel , Sánchez-Castillo Laura , González-Rodríguez Humberto , Kubota Tetsuya , Hasnawir . 
Published: September 2019

Background: Due to causes such as small-scale earthquakes or the increasing amount of heavy rainfall extreme events, many slopes are potentially unstable. Soil bioengineering is an effective tool for treatment of a variety of unstable and/ or eroding sites.
Question and hypothesis: Maximum force to breakage of the roots is influenced by diameter.
Tensile strength and modulus of elasticity of roots is different between species of the two different ecosystems: Tamaulipan thornscrub and Pine-oak forest.
Studied Species: Site 1: Acacia berlandieri, Cordia boissieri, Acacia rigidula, Havardia pallens, and Acacia farnesiana ; Site 2: Quercus rysophylla, Pinus pseudostrobus, Quercus canbyi, Quercus polymorpha, and Arbutus xalapensis .
Study area and dates: Tamaulipan thornscrub in Northeastern Mexico (Linares, Nuevo León), from May to July 2016; and Pine-Oak forest in Sierra Madre Oriental, Iturbide, Nuevo Leon, from September to October 2016.
Methods: The species considered were selected based on their native characteristics (natural distribution, abundance in the area and widespread existence on slopes). The tests were conducted with the Universal Testing Machine Shimadzu type SLFL-100KN.
Results: The relationships between tensile strength (Ts) and diameters of the studied species, and root diameters and modulus of elasticity (Eroot) were negative.
The minimum and maximum values of tensile strength varied from 1.86 N / mm2 in C. boissieri to 44.65 N/mm2 in A. rigidula .
Conclusions: Acacia berlandieri showed the highest tensile strength among all species of the two ecosystems, in the diametric group I (0.1 to 2.9 mm).
Maintenance of high levels of genetic diversity and significant fine-scale genetic structure among age classes in single-tree populations of the endangered epiphytic orchid Laelia speciosa (Orchidaceae) in central Mexico
Authors: Cortes-Palomec Aurea C. , McCauley Ross A. , Oyama Ken 
Published: September 2019

Background: Epiphytic plants exist within the complex three-dimensional habitat of the tree canopy. This can have a profound effect on patterns of both genetic diversity and structure and may be important for conservation of epiphytic species.
Objective: To evaluate how the epiphytic habit affects fine-scale three-dimensional genetic structure in single canopy tree populations.
Studied species: Laelia speciosa , a threatened endemic Mexican epiphytic orchid.
Study site and dates: Field sampling occurred during Spring 2006 in the municipality of Caurio de Guadalupe, Michoacán.
Methods: All individuals occurring in two trees of Q. deserticola (178 in Tree 1 and 276 in Tree 2) were mapped, assigned to four discrete age classes, and genotyped at six microsatellite loci to understand patterns of genetic diversity and structure.
Results: High levels of genetic diversity (polymorphic loci = 100 %, Ho = 0.398 – 0.506) occurred across size classes and trees but were not significantly different between the two trees. Significant fine-scale genetic structure was found in the Juvenile (plants 2-10 years old) and Adults I (11-20 years old) age classes in distances up to 15 cm. This significant structure was larger (up to 25 cm) when all individuals were treated as a single age class.
Conclusion: The distribution and structure of genetic diversity is attributable to the epiphytic habit, particularly localized seed dispersal, limited selfing, and selection of adaptive traits. Conservation implications related to the sampling for in vitro propagation are given in light of the metapopulation genetic variability maintained within single-tree populations.
Phytochemical variation among populations of Fouquieria splendens Engelm. (Fouquieriaceae)
Authors: Monreal-García Hugo Manuel , Almaraz-Abarca Norma , Ávila-Reyes José Antonio , Torres-Ricario Rene , González-Elizondo M. Socorro , Herrera-Arrieta Yolanda , Gutiérrez-Velázquez Marcela Verónica 
Published: September 2019

Background: Secondary metabolites are important chemomarkers. However, as a system to confront biotic and abiotic stress, chemical composition can vary, improving the phenotypic plasticity of plants. We determined the potential of the foliar and floral phenolic composition, floral carotenoid contents to discriminate between two subspecies of Fouquieria splendens and assessed the effect of atypical environmental conditions on the chemical composition of a relict population of the subspecies splendens . Hypothesis: We hypothesized that chemical differences have arisen between the analyzed subspecies and in the relict population allowing the differentiation between them. Species studied: Fouquieria splendens subsp. splendens and Fouquieria splendens subsp. campanulata (Fouquieriaceae). Study site and years of study: Mezquital, Peñón Blanco, and San Juan del Río, Durango, México. March to August 2016. Methods: Foliar and floral extracts were analyzed by HPLC-DAD, UV-visible spectrophotometry, and FTIR-ATR. Multivariate analysis was used to assess the sample distinctiveness and to establish the relation between the chemical composition and environmental variables. Results: The chemical composition was highly conserved between the analyzed samples. Contrarily, an evident distinctiveness between phytochemical contents was observed. Soil parameters were the factors determining the particular quantitative phenolic profiles. Conclusions: The analyzed subspecies and populations showed similar chemical patterns; however, quantitative variations, determined by soil texture, electrical conductivity, organic matter, organic carbon, and contents of K, Ca, and Na, allowed to differentiate them. The important phenolic quantitative variation of the atypical population of F. splendens subsp. splendens suggests a relevant contribution of phenolic compounds to the adaptation to its relict condition.
Historical and contemporary climate legacy of the large-scale distributional patterns of plant richness across different taxonomic levels: An assessment of protected areas in China
Authors: Wang Chun-Jing , Wan Ji-Zhong 
Published: September 2019

Background: Historical and contemporary climates may shape the distributional patterns of plant species richness across different scales. However, few studies have focused on the effects of historical and contemporary climate changes on the distributional patterns of plant richness in Chinese protected areas across different taxonomic levels.
Hypotheses: Historical and contemporary climates can have an important legacy effect on the large-scale distributional patterns of plant richness across different taxonomic levels.
Studied species: Vascular plants.
Study site: China.
Method: We used data on plant richness at the family, genus, and species levels from Chinese protected areas and applied regression modelling to explore the relationships between climate change and plant richness among vascular, fern, seed, gymnosperm, and angiosperm plants based on paleoclimate (Last Glacial Maximum; LGM, ca. 22,000 years ago) and contemporary climate data.
Results: The large-scale distributional patterns of plant richness could be predicted across different taxonomic levels on the basis of paleoclimate and contemporary climate data. Specifically, historical and contemporary climate variables were found to better correlate with fern plant richness than seed plant richness. For seed plants, the explanatory power of historical and contemporary climate variables was found to be stronger for the richness of gymnosperms than for the richness of angiosperms.
Conclusions: The distributional pattern of plant richness could be predicted across different taxonomic levels after including paleoclimate (LGM, ca. 22,000 years ago) and contemporary climate data from China. Our study could support the effectiveness of the management of protected areas in China.
Experimental seed germination for ex situ conservation of Mexican Podostemaceae
Authors: Flores-Enríquez Valeria , Castillo Guillermo , Collazo-Ortega Margarita 
Published: September 2019

Background: Podostemaceae are extremely susceptible to local extinction by habitat loss. Since ~70 % of the river systems in Mexico show some degree of water contamination, it is relevant to generate information about seed storage and germination behavior to design germplasm conservation strategies ( e.g ., ex situ seed banks) of Mexican podostemads.
Hypotheses: Seed germination decreases as seed storage time increases. Further, light quality, temperature and collection site influence similarly the germination response of both species.
Studied species: Marathrum foeniculaceum Humb. & Bonpl., Noveloa coulteriana (Tul.) C. Philbrick
Study site and years of study: 13 different seeds collections (1996-2013), at four locations in the rivers Horcones and Arroyo del Rincon Jalisco, México.
Methods: A germination chamber experiment was performed to evaluate the effect of temperature, light quality and storage time on the germination of both species.
Results: Seeds lose viability after nine years of storage. In both species, the time to reach the highest Accumulated Germination Percentage (AGP) was faster in seeds of one-two yr compared to seeds of six-seven yr. N. coulteriana have significant differences in Final Germination Percentage (FGP) between collection rivers. Storage time affects AGP of N. coulteriana more than in M. foeniculaceum.
Conclusions: Both species can form ex situ seed banks up to 8 yr age in paper bags storage. N. coulteriana is more susceptible to variation in storage conditions compared to M. foeniculaceum . Collection site affect seed germination after storing. Long-term conventional ex situ seed germination storage is not a viable strategy to conserve germplasm of Podostemaceae.
An Examination of Competitive Balance within Interscholastic Football
Authors: Johnson James E , Manwell Allison K , Scott Beau F 
Published: September 2019

Interscholastic football has the highest participation rates among high school students in the United States. The popularity and nostalgic connection of football is widespread, but competitive balance is often challenged due to differing characteristics of high schools. This study utilized the theory of distributive justice and data from high school athletic associations in all 50 states and District of Columbia to consider which variables (public/private status, school population, rural/urban location, geographical region, and policies) may impact competitive balance at the state-championship level of interscholastic football. The results confirmed that traditionally strong private schools generally located in the Midwest and Northeast win state titles at disproportionately high rates. No other variable was as powerful or significant as the public/private variable. The findings of the study also challenged the effectiveness of existing policies designed to curb private school success. These results can serve pragmatic efforts to ensure competitive balance within interscholastic football.
The Verbal Aggression of Spectators at Youth Baseball Games: Investigating the Impact of Competition Level, Team Identification, and Fan Dysfunction
Authors: Wann Daniel L. , Sherman Michelle R. 
Published: September 2019

Previous research had found that level of team identification was positively associated with aggression at youth sporting events (Wann, Weaver, Belva, Ladd, & Armstrong, 2015). The current investigation was designed to extend this work by incorporating fan dysfunction into the model (i.e., fans who are confrontational and frequently complain). Spectators at either a recreational or select (i.e., travel) youth baseball game completed a survey packet assessing demographics, team identification with their favorite Major League Baseball team, identification with the youth team, fan dysfunction, and hostile and instrumental verbal aggression directed toward officials and opponents. Results indicated that, contrary to expectations, team identification was not a unique predictor of verbal aggression. Rather, fan dysfunction predicted each form of aggression, aggression toward both targets, and total aggression.
Qualidade nutricional e parâmetros morfológicos do fruto cajá (Spondias Mombin L.)
Authors: Silvino Rayssa , Silva Graziela , Dos Santos Orquídea Vasconcelos 
Published: September 2019

O aumento no consumo e na produção de frutas tropicais promove a necessidade de pesquisas direcionadas a novas vertentes de compostos Nutricionais e funcionais da biodiversidade Amazônica. Assim, o objetivo desta pesquisa e rastrear a qualidade nutricional-funcional e os parâmetros morfológicos do fruto cajá (spondias mombin l.). As bases metodológicas e métodos aplicados seguem o padrão de análise internacionalmente aceitas indicados pela Association of Official Analytical Chemists (AOAC). Os resultados obtidos apresentaram um fruto de considerável valor nutricional com baixo valor energético e alta relevância em compostos funcionais com a vitamina C com médias de 25,37 mg ácido ascórbico/100g e seu teor de carotenoides totais o valor médio de 1498,57 (?g.100g-1) mostrando a relevância desse fruto em provitamina A. As micrografias das estruturas mostram uma matriz vegetal com presença de fibras e de raros grânulos de amido. A presença de fibras e das vitaminas A e C nesta composição aliado com seu baixo valor energético mostra a capacidade de prevenção de determinadas patologias que o consumo deste fruto pode oferecer.
NEW TREATMENT OPTION FOR ESOPHAGOGASTRIC ANASTOMOTIC LEAK: A CASE REPORT
Authors: Davydov M. M. , Abdullaev A. G. , Malikhova O. A. , Tsigankova A. V. 
Published: September 2019

The formation of esophagogastric anastomosis has a long history due to the search for the most reliable and safe fistula. The use of invagination anastomosis, proposed in the early 90s by Professor M.I. Davydov, fully met all the requirements, allowing significantly improve the quality of life of patients and significantly reducing the frequency of failure of the anastomoses to 0.5%.Case description. We present the case of proximal gastric cancer invading the lower thoracic esophagus. The patient underwent proximal subtotal gastric and lower thoracic esophageal resection using the combination of a laparotomy and right thoracotomy. Contrast radiography performed on day 11 after surgery revealed esophagogastric anastomotic leak. The patient underwent urgent surgery.Conclusion. This article presents a new treatment option for esophagogastric anastomotic leak by using endoscopic transesophageal clipping of the defect in combination with sanitation and drainage of the pleural/mediastinsl cavity. The proposed technique can be considered as a minimally invasive treatment method and can be used in any surgical clinic.
CRYOSURGERY IN THE TREATMENT OF LIVER CANCER: A CASE REPORT
Authors: Merzlikin N. V. , Petrov L. U. , Tskhai V. F. , Pshenichnikova E. A. , Sarueva A. P. 
Published: September 2019

Background. Hepatocellular carcinoma is the most common liver cancer and is a leading cause of cancerrelated death worldwide. Its aggressiveness and extensive dissemination lead to a poor patient prognosis. The 5-year survival rate does not exceed 15 %. Despite advances in imaging techniques, its curable rate remains low, because signs and symptoms of liver cancer do not usually appear until the late stages. There is no standard curative treatment for advanced liver cancer.Description. We present the case of a 56- year-old female patient with stage T3N0M0 hepatocellular carcinoma. The patient had a tumor of 20 cm in diameter and 2400 g in weight. The patient underwent right hemihepatectomy and cryodestruction of the liver stump along the resection margin. No evidence of tumor recurrence was found with a follow-up of 12 years.Conclusion. Cryodestruction of the liver stump along the resection margin increases the potential for a higher cure rate in patients with hepatocellular carcinoma, even in cases of extensive organ damage in the absence of metastasis and tumor ingrowth into surrounding organs.
UNCONVENTIONAL FRACTIONATION RADIOTHERAPY REGIMENS IN TREATMENT OF INOPERABLE LUNG CANCER
Authors: Gogolin D. V. , Gulidov I. A. , Medvedeva K. E. , Ragulin Y. A. , Mardinsky Y. S. , Ivanova I. N. , Kursova L. V. , Kotuhov I. I. , Buksha A. Y. 
Published: September 2019

The purpose of the study was to compare the efficacy and toxicity of hypofractionated versus hyperfractionated radiotherapy in patients with inoperable lung cancer.Material and Methods. Patients with inoperable lung cancer, who were treated between 2014 and 2017, were assigned to undergo radiotherapy in two arms: accelerated hypofractionated conformal radiotherapy arm with 70 patients (60 Gy in 25 fractions, with 2.4 Gy per fraction) and accelerated hyperfractionated radiotherapy with 49 patients (60–70 Gy with 1–1.5 Gy per fraction). At the same time, platinum-based chemotherapy was applied.Results. The rates of partial response, complete response, stable disease and progressive disease were 44.3, 7.2, 38.5 and 10.0 %, respectively in patients with hypofractionated conformal radiotherapy arm. The corresponding values were 71.4, 6.1, 16.4 and 6.1 %, respectively in patients with hyperfractionated radiotherapy arm. The 2-year overall survival rate was 62.8 % for the hypofractionated group and 58.1 % for the hyperfractionated group. Esophagitis III grade was observed in 4 (5.7 %) patients of the hypofractionated group and in 3 (6.5 %) patients of the hypofractionated group. Pneumonitis III grade was reported in 2 (2.9 %) patients in the hypofractionated radiotherapy arm and in 4 (8.7 %) patients in the hyperfractionated radiotherapy arm.Conclusion. Results of the study showed that 3D-conformal hypofractionated radiotherapy combined with concurrent chemotherapy resulted no in severe radiation-induced complications, and demonstrated satisfactory short-and long-term treatment outcomes.
PROSPECTS FOR SEARCHING MULTITARGET TOPOISOMERASE INHIBITORS WITH ANTITUMOR PROPERTIES
Authors: Treshchalin M. I. , Neborak E. V. , Treshchalina H. M. 
Published: September 2019

Purpose of research: to identify the prospects of search for new antitumor non-camptothecin inhibitors of topoisomerase I/II among the various chemical compounds based on the analysis of side effects.Material and Methods. The analysis included 65 relevant literature sources for 2002–2018 years, found in Systems such as Scopus, Web of Science, Pubmed, and eLIBRARY.Results. The antitumor and side effect characteristics of the agents, associated with the selective suppression of the activity of type I and/or II topoisomerase (Top1, Top2) in tumor cells were emphasized. Examples of the relationship between side effects of inhibitors and their structure and catalytic mechanisms were given. The following factors were highlighted as significant: 1) blocking of cells in G2 and S phases with a delay of entry into mitosis; 2) inhibition of the reaction of re-ligation with DNA breaks without re-linking; 3) launching of cytotoxic events with the inhibition of DNA replication and generation of double-strand breaks. Incurable cancers, such as gastric cancer, colorectal cancer, non-small cell lung cancer, hepatocellular carcinoma, glioblastoma, etc. were determined as more sensitive to inhibitors. Side effects of treatment and their connection with the mechanism of activity were described.Conclusion. Based on the comparative analysis of prognostically valuable data regarding the efficacy and safety of topoisomerase I/II inhibitors, multitargeted heterocyclic condensed nitrogen-containing compounds, in particular, anthrafurans, can be considered as new promising clinical candidates with higher selectivity of action.
THE VALUE OF PET/CT IN THE DIAGNOSIS, STADING AND MONITORING OF COLORECTAL CANCER
Authors: Chernov V. I. , Goncharova N. M. , Goldberg V. E. , Dudnikova E. A. , Zelchan R. V. , Medvedeva A. A. , Sinilkin I. G. , Bragina O. D. , Avgustinovich A. V. , Goldberg A. V. , Ermolenko R. V. , Popova N. O. , Simolina E. I. , Vysotskaya V. V. 
Published: September 2019

The purpose of the study was to provide up-to-date data on the efficacy of positron emission computed tomography (PET) for the diagnosis, assessment of tumor extension and monitoring of colorectal cancer.Material and Methods. The Medline and Pubmed databases were used for searching for publications devoted to clinical trials of diagnostic value of PET with 18F-Ftordesoxyglucose (PET with 18F-FDG).Results. Data on the value of PET with 18F-FDG in visualization of the primary tumor, detection of lymph node and distant metastases and assessment of the treatment response in patients with colorectal cancer were presented.Conclusion. PET with 18F-FDG was shown to be a promising imaging method for colorectal cancer. It is the most sensitive method in the detection of liver metastases. 18F-FDG PET is particularly superior to CT and MET in the ability to assess tumor response to treatment and predict early tumor response to therapy. The development of new radiopharmaceuticals for the diagnosis, staging, monitoring and prediction of colorectal cancer is of great importance.