bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences In The Effectiveness Of Binahong Leaf Boiled Compresses And Red Betel Leaf Boiling For Healing Perineal Wounds In Post Partum Mothers
Authors: Islamiyati Islamiyati , Sadiman Sadiman , Yuliawati Yuliawati 
Published: November 2024

Latar Belakang: Ruptur perineum merupakan perlukaan jalan lahir yang terjadi saat kelahiran bayi baik menggunakan alat maupun tidak menggunakan alat. Dampak apabila luka perineum tidak dirawat dengan baik adalah terjadi infeksi pada ibu nifas. Infeksi pada ibu nifas merupakan salah satu penyebab kematian pada ibu post partumTujuan: Untuk melihat perbedaan efektifitas penyembuhan luka perineum dengan menggunakan air rebusan daun binahong dan air rebusan sirih merah di TPMB Kiswari Kota MetroMetode: Penelitian quasi experiment dengan rancangan Non equivalent control group design. Populasi semua ibu nifas dengan robekan perineum dengan sampel 12 orang tiap kelompok intervensi diambil secara random. Analisis Bivariat akan menggunakan uji t test independenHasil: Terdapat perbedaan efektivitas air rebusan binahong dan air rebusan sirih merah dalam penyembuhan luka robekan perineum dengan p value sebesar 0,002Kesimpulan: Penggunaan kompres air rebusan binahong lebih efektif dibandingkan dengan kompres air rebusan sirih merah dalam penyembuhan luka robekan perineumSaran : kepada bidan praktik mandiri agar mulai menggunakan terapi non farmakologi dalam penyembuhan luka robekan perineum terutama menggunakan kompres air rebusan binahongKata Kunci : Luka Robekan Perineum, Binahong, Sirih Merah ABSTRACT Background: Perineal rupture is a birth canal injury that occurs during the birth of a baby, whether using tools or not using tools. The impact if the perineal wound is not treated properly is that infection occurs in the postpartum mother. Infection in postpartum mothers is one of the causes of death in postpartum mothersPurpose: To see the difference in the effectiveness of healing perineal wounds using boiled water from binahong leaves and boiled water from red betel at TPMB Kiswari Metro CityMethod: Quasi experimental research with a non-equivalent control group design. The population of all postpartum mothers with perineal tears with a sample of 12 people per intervention group were taken randomly. Bivariate analysis will use the independent t testResults: There is a difference in the effectiveness of binahong boiled water and red betel boiled water in healing perineal lacerations with a p value of 0.002Conclusion: Using binahong boiled water compresses is more effective than red betel boiled water compresses in healing perineal lacerationsSuggestion: for independent practicing midwives to start using non-pharmacological therapy in healing perineal lacerations, especially using binahong boiled water compresses Keywords: Perineal Tears, Binahong, Red Betel
Determinan Kepatuhan Remaja Putri Tingkat SMA di Kota Ruteng Dalam Mengonsumsi Tablet Fe
Authors: Dewi Imelda Rosniyati , Centis Maria Choncita Leyla , Trisnawati Reineldis E E 
Published: November 2024

ABSTRACT Investments in sexual and reproductive health and rights, including for adolescent girls, can provide enormous economic and social returns. WHO recommendations agreed on a global action plan and targets for maternal, infant and child nutrition, with a commitment to halve (50%) the prevalence of anemia in adolescents and WUS by 2025 by prioritizing the provision of TTD through school institutions. The purpose of this study was to determine the determinants of factors affecting adolescents' adherence in consuming Fe. The method used in this study was quantitative-cross sectional with chi-square analysis test involving 80 female students. The test results showed the þ value of the relationship between knowledge and adherence of adolescent girls (0.3), attitudes with adherence of adolescent girls (0.1), and support (family and teachers) with adherence of adolescent girls in consuming Fe (1.0). There is no relationship between knowledge, attitude and support to the compliance of adolescent girls in consuming Fe. Keywords: Adolescent Girls, Adherence, Fe Tablets ABSTRAK Investasi dalam kesehatan dan hak-hak seksual dan reproduksi, termasuk untuk remaja perempuan, dapat memberikan keuntungan ekonomi dan sosial yang sangat besar. Rekomendasi WHO menyepakati rencana aksi dan target global untuk gizi ibu, bayi, dan anak, dengan komitmen mengurangi separuh (50%) prevalensi anemia pada remaja dan WUS pada tahun 2025 dengan memprioritaskan pemberian TTD melalui institusi sekolah. Tujuan penelitian ini adalah untuk mengetahui determinan faktor yang memengaruhi kepatuhan remaja dalam mengonsumsi Fe. Metode yang digunakan dalam penelitian ini adalah kuantitatif-cross sectional dengan uji analisis chi-square yang melibatkan 80 siswi. Hasil uji menunjukkan þ value hubungan pengetahuan dengan kepatuhan remaja putri (0.3), sikap dengan kepatuhan remaja putri (0.1), dan dukungan (keluarga dan guru) dengan kepatuhan remaja putri dalam mengonsumsi Fe (1.0). Tidak ada hubungan antara pengetahuan, sikap dan dukungan terhadap kepatuhan remaja putri dalam mengonsumsi Fe. Kata Kunci: Remaja Putri, Kepatuhan, Tablet Fe
Pengaruh Pemberian Madu terhadap Penurunan Frekuensi Batuk Pada Anak di RSIA Sitti Khadijah Kota Gorontalo
Authors: Modjo Dewi , Sudirman Andi Akifa , Rias Rianti U 
Published: November 2024

ABSTRACT Coughing in children, if it cannot be done above, can cause blockages in the airways and cause more serious problems such as severe tightness to death due to blockages in the airways due to the large amount of sputum production during coughing, so to prevent this, honey can be given to reduce the frequency of coughing. This study aims to analyze the effect of honey administration on reducing cough frequency in children at RSIA Sitti Khadijah, Gorontalo City. This study aims to analyze the effect of honey administration on reducing cough frequency in children at RSIA Sitti Khadijah, Gorontalo City. This study is a quantitative research using a One group pre-test and post-test design design that provides treatment or intervention to the research subject and then the effect of the treatment is measured and analyzed. This sampling uses purposive sampling with a total of 15 samples. The results of the analysis of the average frequency of children's cough before being given honey was 10.33 with a standard deviation of 2.636 and the average frequency of children's cough after being given honey was 5.73 with a standard deviation of 1.223, and a p-value of 0.000 which means that there was an effect of honey administration on the reduction of cough frequency in children at RSIA Sitti Khadijah, Gorontalo City. Keywords: Children, Cough Frequency, Honey ABSTRAK Batuk pada anak apabila tidak dapat diatas dapat mengakibatkan sumbatan pada jalan nafas dan menimbulkan masalah yang lebih berat seperti sesak yang hebat hingga kematian akibat sumbatan pada jalan nafas karena banyaknya produksi sputum saat batuk sehingga untuk mencegah hal tersebut dapat diberikan madu untuk mengurangi frekuensi batuk. Penelitian ini bertujuan untuk menganalisis pengaruh pemberian madu terhadap penurunan frekuensi batuk pada anak di RSIA Sitti Khadijah Kota Gorontalo. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan desain One group pre-test and post-test design yang memberikan perlakuan atau intervensi pada subyek penelitian kemudian efek perlakuan tersebut diukur dan dianalisis. Pengambilan sampel ini menggunakan purposive sampling dengan jumlah 15 sampel. Hasil analisis rata-rata frekuensi batuk anak sebelum diberikan madu adalah 10,33 dengan standar deviasi 2,636 dan rata-rata frekuensi batuk anak sesudah diberikan madu adalah 5,73 dengan standar deviasi 1,223, serta p-value 0,000 yang artinya ada pengaruh pemberian madu terhadap penurunan frekuensi batuk pada anak di RSIA Sitti Khadijah Kota Gorontalo. Kata Kunci: Anak, Frekuensi Batuk, Madu
Analysis of Hemodialysis Service Unit Development in Sri Pamela Hospital Tebing Tinggi
Authors: Armaya Dita , Ginting Chrismis Novilda , Napiah Ali 
Published: November 2024

ABSTRACT Indonesia currently following the global non-communicable disease trend, such as the growth of chronic kidney disease and end-stage kidney disease numbers. In the last eight years, the number of end-stage kidney disease patients jumped from 9.649 to 66.433 (2010-2018). One of the consequences of this increasing incidence is the increasing need for kidney replacement therapy, one being hemodialysis. Strength-Weakness-Opportunity-Threat (SWOT) analysis in a common business tool used to assess and evaluate the feasibility of business development and/or expansion. This study aims to assess the potential of the development of a hemodialysis unit in Sri Pamela Tebing Tinggi Hospital. This study is an analytical descriptive evaluation study. Data in this study was gathered from three key informants (nephrologist-in-charge, head of the hemodialysis unit, and hemodialysis nurse) and two additional informants (regular hemodialysis patients) in Sri Pamela Tebing Tinggi Hospital. Data gathered from this study was analyzed using Internal-External (IE) and SWOT matrix. This study discovers that the existing hemodialysis unit in Sri Pamela Tebing Tinggi Hospital stands on the first quadrant of the IE matrix, grows and is built with vertical integration, and is at S-O strategy in the SWOT matrix. According to these findings, it can be concluded that the Sri Pamela Tebing Tinggi Hospital's hemodialysis unit has great potential for further development by expanding its service capacity by expanding its building, adding more hemodialysis machines along with more manpower. Keywords: ESRD, Hemodialysis, Hospital Management, SWOT
Penggunaan DAPT (Dual Antiplatelet) Pada CVA (Cerebrovascular Accident) Trombosis atau Stroke Iskemik dengan Riwayat PJK (Penyakit Jantung Koroner)
Authors: Putri Rizky Ayu Artama , Badriah Rani Nur , Pratama Jainuri Erik , Setiadi Antonius Adji Prayitno , Herawati Fauna , Gondokesumo Marisca Evalina 
Published: November 2024

ABSTRACT Ischemic stroke is the sudden development of focal neurological deficit due to inadequate blood supply to an area of the brain, which can be thrombotic or embolic. CAD (Coronary Artery Disease) is pathological process characterized by the formation of atherosclerotic plaque followed by rupture, ulceration, or erosion. CAD can take the form of CCS (Chronic Coronary Syndrome). The 2018 AHA/ASA Guidline Antiplatelet Therapy used for ischemic stroke is Aspirin at a dose of 160mg-300mg 1x1. In the 2019 ESC Guidline, CCS patient therapy uses DAPT (Dual antiplatelet). In a 2021 AHA meta-analysis compared with aspirin alone, short-term DAPT within 24 hours after mild-moderate ischemic stroke reduced the risk of recurrent stroke at the expense of a higher risk of major bleeding. Here we present a case of a 76 year old female patient with ischemic stroke and CCS who used DAPT. Complaints of sluggishness, weakness in the left half of the body, acute dysarthria onset on the first day, when waking up. Hemiplegia S 1 week ago onset of waking up and being treated at Mataram Regional Hospital. The patient received the antiplatelet Aspirin 160mg 1x1 a day then switched DAPT (Aspirin 80mg 1x1 and Clopidogrel 75mg 1x1) due to a history of CCS. Keywords: CVA Thrombosis, Ischemic stroke, Aspilet, Clopidogrel, Coronary Artery Disease ABSTRAK Stroke iskemik adalah perkembangan fokal yang tiba-tiba terjadi defisit neurologis akibat suplai oksigen tidak memadai ke suatu area pada otak, dapat bersifat trombotik atau emboli. PJK (Penyakit Jantung Koroner) atau CAD (Coronary Artery Disease) adalah proses patologis ditandai dengan terbentuknya plak aterosklerotik diikuti dengan pecah, ulserasi, atau erosi. PJK dapat berupa penyakit CCS (Chronic Coronary Syndrome). Terapi Antiplatelet Guidline AHA/ASA 2018 yang digunakan pada stroke iskemik adalah Aspirin dosis 160mg-300mg 1x1. Pada Guidline ESC 2019 terapi pasien CCS digunakan DAPT (Dual antiplatelet). Pada meta analisis AHA 2021 dibandingkan dengan aspirin saja, DAPT jangka pendek dalam waktu 24 jam setelah stroke iskemik ringan-sedang mengurangi risiko stroke berulang dengan mengorbankan risiko perdarahan besar yang lebih tinggi. Berikut kami presentasikan sebuah kasus pasien Perempuan 76 tahun dengan Stroke Iskemik dan CCS yang menggunakan DAPT. Keluhann pelo, kelemahan separuh badan kiri, acute disartria onset hari pertama, saat bangun tidur. Hemiplegia S 1 minggu lalu onset bangun tidur di rawat di RSUD Mataram. Pasien menerima antiplatelet Aspirin 160mg 1x1 sehari lalu switch DAPT (Aspirin 80mg 1x1 dan Clopidogrel 75mg 1x1) karena Riwayat CCS. Kata Kunci: CVA trombosis, Ischemic stroke, Aspilet, Clopidogrel, Penyakit Jantung Koroner.
Comparison of patients undergoing protected high risk percutaneous coronary intervention using either intravascular lithotripsy or rotational atherectomy
Authors: Krause Tobias T. , Afzal Shazia S. , Gjata Anida , Lindner Michael , Saad Louai , Steinbach Mirjam , Zayat Rashad , Haneya Assad , Werner Nikos , Leick Juergen 
Published: November 2024

BackgroundTreating heavily calcified vessels is a challenging task in patients with an impaired left ventricular ejection fraction. Percutaneous mechanical circulatory support (pMCS) is increasingly used in patients in high-risk percutaneous coronary intervention (HRPCI).MethodsIn this retrospective registry, we investigated 25 patients undergoing a protected HRPCI receiving either intravascular lithotripsy (IVL + pMCS; n = 11) or rotational atherectomy (RA + pMCS; n = 14). The primary endpoint was defined as peri-interventional hemodynamic stability. The secondary endpoint was defined as major adverse cardiac events (MACE).ResultsPatients in the IVL + pMCS group had a significantly higher mean arterial pressure (MAP) at the end of the procedure (p = 0.04). However, the Δ-change in MAP was not significant [−12 mmHg (±20.3) vs. −16.1 mmHg (±23.9), p = 0.709]. The proportion of patients requiring post-interventional catecholamines was significantly lower in the IVL + pMCS group (p = 0.02). The Δ-change in Syntax Score was not significant between groups (IVL + pMCS −22 (±5.8) vs. RA + pMCS −21.2 (±7.6), p = 0.783). MACE did occur less in the group of IVL + pMCS (0% vs. 20%, p = 0.046). Patients with pMCS insertion as a bailout strategy had a higher probability for in-hospital death (p &lt; 0.001) and the occurrence of the slow-reflow phenomenon was associated with long-term mortality (p = 0.021) in the cox regression analysis.ConclusionsIn our cohort patients in the IVL + pMCS group were hemodynamically more stable which led to a lower rate of catecholamine usage. pMCS as a bailout strategy was associated with in-hospital death and the occurrence of the slow reflow phenomenon with all-cause mortality during follow-up.
Measuring ethnocultural empathy in Japanese undergraduates: the validity and reliability of the Japanese version of the scale of ethnocultural empathy
Authors: Ostman David , Xethakis Larry 
Published: November 2024

IntroductionThe purpose of this study was to adapt the English version of the Scale of Ethnocultural Empathy (SEE) for use in the Japanese context and to determine the validity and reliability of the adapted version to allow for the measurement of cultural empathy and promote further research into this concept in Japan. The SEE is a widely-used measure of cultural empathy which has been adapted for use in a number of cultures (e.g., Turkish, Swedish, Spanish), however the validity and reliability of this scale in the Japanese context has yet to be determined. While recognition of the importance of learner empathy in intercultural interactions has increased, at present, a validated scale to measure ethnocultural empathy has not been presented.MethodsResponses from 777 Japanese undergraduate students were used to determine the construct validity of the SEE using exploratory and confirmatory factor analysis, as well as to assess the convergent validity of the scale using the Interpersonal Reactivity Index (IRI). Reliability was evaluated using Cronbach’s alpha and test-retest validity.ResultsFactor analysis revealed two factors underlying the Japanese version of the SEE (SEE_J), explaining 42.1% of variance. The two factors—Empathic Feeling and Expression (EFE_J) and Empathic Awareness and Perspective Taking (EAPT_J)—were moderately correlated. Correlations between the SEE_J, EFE_J and EAPT_J with two subscales of the IRI provided evidence of convergent validity. The SEE_J, EFE_J and EAPT_J displayed sufficient internal and test-retest reliability. Respondents reported significantly higher levels of EFE_J than EAPT_J, and women reported significantly higher SEE_J and EFE_J than men, both of which are similar to the results of past studies using the SEE in other cultural contexts.DiscussionThe validation of the SEE_J allows for the measurement of cultural empathy and further research into this concept in the Japanese context, as well as the development of programs to enhance ethnocultural empathy in areas where Japanese individuals come into contact with individuals from other cultures, such as counseling, healthcare and education.
Extrinsic electric field modulates neuronal development and increases photoreceptor population in retinal organoids
Authors: Rajendran Nair Deepthi S. , Gupta Anika , Iseri Ege , Wei Tianyuan , Phuong Quach Le Tam , Seiler Magdalene J. , Lazzi Gianluca , Thomas Biju B. 
Published: November 2024

IntroductionConsidering the significant role played by both intrinsic and extrinsic electric fields in the growth and maturation of the central nervous system, the impact of short exposure to external electric fields on the development and differentiation of retinal organoids was investigated.MethodsRetinal organoids derived from human embryonic stem cells were used at day 80, a key stage in their differentiation. A single 60-minute exposure to a biphasic electrical field was administered to assess its influence on retinal cell populations and maturation markers. Immunohistochemistry, qPCR, and RNA sequencing were employed to evaluate cell type development and gene expression changes.ResultsElectrical stimulation significantly enhanced neuronal development and increased the population of photoreceptors within the organoids. RNA sequencing data showed upregulated expression of genes related to rod photoreceptors, Müller cells, horizontal cells, and amacrine cells, while genes associated with retinal pigment epithelium and retinal ganglion cells were downregulated. Variations in development and maturation were observed depending on the specific parameters of the applied electric field.DiscussionThese findings highlight the significant impact of extrinsic electrical fields on early retinal development and suggest that optimizing electrical field parameters could effectively address certain limitations in retinal organoid technology, potentially reducing the reliance on chemicals and small molecules.
Tilt training as a treatment for reflex syncope: a multimodal approach!?
Authors: Hornikx Miek , Haemers Peter , Stans Linda , Robyns Tomas , Garweg Christophe , Ector Joris , Vandenberk Bert , Willems Rik 
Published: November 2024

PurposeReflex syncope is a burdensome disease with considerable repercussions on the quality of life. Tilt training is a therapeutic option, but evidence on this topic is scarce and outdated. Hyperventilation is oftentimes associated with reflex syncope. This study aimed to evaluate the effectiveness of tilt training in patients with reflex syncope and study the association between reflex syncope and hyperventilation.MethodsPatients referred for tilt training after a positive tilt test from July 2014 to March 2021 were included in a single-center, retrospective registry. Demographic characteristics and outcomes of the program were collected. The response of tilt training on (pre)syncope recurrence and the association with hyperventilation were studied.ResultsA total of 173 patients were included. The median age was 27 [17–48] years. Patients needed 2 [1–3] sessions to reach the first negative tilt training. The tilt training program was successfully completed by 65% of patients. An additional 3% reported no complaints in daily life, despite remaining symptomatic during tilt training. Another therapy was initiated in 10% of patients, while 21% dropped out of the tilt training. Presyncope recurred in 21% of patients during a follow-up period of 21 months [16–23]. Concomitant hyperventilation was suspected in 24%. Among these patients, 74% were referred for a hyperventilation provocation test, which confirmed the diagnosis in 82%.ConclusionWe report a reasonable success of tilt training in a contemporary cohort of patients. In patients completing the tilt training program, presyncope, and syncope recurrence was low. Concomitant hyperventilation seems prevalent in patients with reflex syncope and warrants specific attention and treatment.
Perineural spread evaluation of cranial nerves in nasopharyngeal carcinoma: superiority and reliability of isovolumetric MR imaging
Authors: Zheng Dechun , Xu Shugui , Lai Guojing , Hu ChunMiao , Cao Xisheng , Feng Meimei , Peng Li 
Published: November 2024

PurposeThe purpose of this study was to investigate the advantage of three-dimensional liver acquisition with volume acceleration-flexible (3D LAVA_Flex) for perineural spread (PNS) status of nasopharyngeal carcinoma (NPC) in comparison with two-dimensional magnetic resonance sequences.Materials and methodsSixty pathological proved NPC patients were prospective enrolled. A protocol included T2-weighted imaging with fat suppression (T2WI fs), T1-weighted imaging (T1WI) without and with contrast enhancement (T1WI ce), and 3D LAVA_Flex was applied for the recruited subject. After determining radiologic diagnostic criteria, the PNS status of cranial nerves (CNs) was carefully interpreted and recorded at the nerve level, anterior and posterior subgroup level, and individual level, respectively. Chi-square test [or McNemar-Bowker (MB) test], Fisher test, and intraclass correlation analysis were used. A P &lt; 0.05 indicated statistical significance.ResultsPNS rates of the CNs in the advanced T3 to T4 stage subgroup were significantly different in evaluations performed with 3D LAVA_Flex, T2WI fs, T1WI, and T1WI ce at the patient level (n = 51, MB test, all P ≤ 0.031) and posterior CN level (MB test, all P ≤ 0.016). At the nerve level, 3D LAVA_Flex showed greater PNS detectability than T2WI fs, T1WI, and T1WI ce for CN V3 division (P = 0.031, 0.016, and 0.016, respectively), hypoglossal nerve (P = 0.002, 0.016, and 0.008, respectively), and external posterior CN IX–XII in carotid space (all P = 0.001), and T2WI fs and T1WI for CN IX–XI (P = 0.031, 0.001).Conclusions3D LAVA_Flex could improve both accuracy and reliability of PNS evaluation of CNs in the advanced NPC cohort and may facilitate decision making for therapeutic strategies.