bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalencia y factores asociados del intento de suicidio en estudiantes de ciencias de la salud
Authors: Ronald Solano-De La Cruz  , Fermin Caceres-Bellido  
Published: September 2019

Objetivo: Determinar la prevalencia y los factores personales, familiares y ambientales, asociados con el intento de suicidio en estudiantes de ciencias de la salud de la Universidad Nacional San Luis Gonzaga de Ica. Materiales y métodos: Se desarrolló un estudio observacional, transversal, descriptivo yprospectivo en estudiantes matriculados en el año académico 2012 en la Universidad San Luis Gonzaga de Ica, Perú; pertenecientes a las facultades de Ciencias de la Salud (Medicina Humana, Enfermería, Odontología, Farmacia y Bioquímica y Biología). La muestra estuvo proporcional por cada facultad, estuvo conformada por 337 estudiantes que aceptaron participar en el estudio mediante consentimientoinformado. Resultados: Un total de 28 (8,31%) estudiantes había intentado suicidarse alguna vez, la mayor frecuencia de antecedente de intento de suicidio se encontró en las facultades de Farmacia y Bioquímica (7; 11,1%) y en la de Odontología (8; 10,3%) y la menor frecuencia se halló en la facultad de Medicina (2; 3,0%). La edad promedio del primer intento fue a los 15,5±0,86 años, con un promedio de1,5±0,26 intentos. Se asociaron al intento de suicidio el maltrato infantil (p<0,05), el castigo físico (p<0,01) y castigo psicológico (p<0,01) (en la última semana), amigos con intento de suicidio (p<0,01), provenir de familias disfuncionales (p<0,01), y sufrir de depresión (p<0,05). Conclusiones: La prevalencia de intento de suicidios en estudiantes universitarios de ciencias de la salud es 8,31% y se asocia a antecedente de maltrato infantil, castigo psicológico o físico en la última semana, presencia de intentos suicidas en amigos, disfunción familiar y depresión.
Kondisi fisik kelautan habitat ditemukannya Latimeria menadoensis di selatan Teluk Manado
Authors: Ali Isti Utami Indah Sari , Masengi Kawilarang W. A. , Manu Lusia , Luasunaung Alfret , Polii Janny F. , Pamikiran Revols D. Ch , Thamin Arman 
Published: September 2019

The movement of the water mass on the ocean or known as current is a very complex natural phenomenon. That related to the variation of the controlling factors. This research was based on descriptive method to obtain the information about the problem being studied. Data collected by operating the three oceanographic tools that area floater current meter, tidal gauges, and wave gauges. Data collection were carried out during the day and night of two locations which tidal and wave high were measured at 1O 27 '39.90 " N and 124O 49' 7.84" E and 1O 28’ 22.86” N, 124O 48’ 40.6” E. Current was measured by eularian and lagrangian methods. Current pattern on the location of Latimeria menadoensis was catched shown that the current direction was eastward last quarter and contrast on fullmoon with the mean wave energy is 1.46 joule.ABSTRAKPergerakkan massa air atau dikenal dengan arus merupakan fenomena yang sangat kompleks. Hal ini berkaitan dengan besarnya variasi dari faktor-faktor pengontrol terjadinya arus di perairan. Penelitian ini dilakukan dengan metode deskriptif yaitu untuk memperoleh informasi tentang persoalan yang sedang diteliti. Pengumpulan data dilakukan dengan cara mengoperasikan tiga alat pengukur kondisi oseanografis, yaitu alat pengukur arus (floater current meter), alat pengukur pasang surut, dan alat pengukur gelombang. Pengambilan data dilaksanakan pada siang hari dan malam hari yang dilakukan pada dua titik lokasi pengambilan data yaitu, lokasi pengambilan data pasang surut dan gelombang pada titik GPS 1O 27’ 39.90” N, 124O 49’ 7.84” E (pesisir pantai) dan lokasi pengambilan data arus metode eularian dan lagrangian pada area sekitar titik GPS 1O 28’ 22.86” N, 124O 48’ 40.6” E (± 0,82 mil laut dari pesisir pantai). Pola arus dimana Latimeria menadoensis tertangkap menunjukkan dominan ke arah timur pada saat perbani akhir dan berlawanan saat bulan purnama dengan energi gelombang rata-rata sebesar 1.46 joule.
Demand of Public-Private Partnerships for Infrastructure Bonds for Municipal Development
Authors: Gorovoy A. A. , Sorokina V. A. 
Published: September 2019

The presented study examines the crucial problem of our time — the need to develop an infrastructure mortgage mechanism that would maintain and reproduce infrastructure resources.Aim. The study aims to consider the possibility of using infrastructure bonds for public-private partnership projects.Tasks. The authors determine the features of infrastructure bonds, briefly analyze foreign experience of their use, and outline an infrastructure municipal loan.Methods. This study uses general scientific methods of cognition to consider the possibility of using infrastructure bonds for public-private partnership projects.Results. Infrastructure bonds issued for public-private and municipal-private partnership projects can serve as a financial tool for infrastructure development or as a mortgage payment. Infrastructure bonds should be long-term and targeted, issued for the corresponding infrastructure projects. A competent approach to the preparation and implementation of an infrastructure loan requires the issuer’s professional agents to formulate the optimal loan concept and then put this concept into practice based on the optimal issuance parameters determined according to loan marketing among potential investors.Conclusions. The issuance of infrastructure bonds will make it possible to meet the demand of publicprivate partnerships for investment resources and sustainable investment projects. An infrastructure mortgage scheme should accommodate the interests of both the investor and infrastructure users.
Peranan Economic Order Quantity dalam peningkatan Efisiensi pengelolaan persediaan pada PT. Martina Berto Tbk.
Authors: Tarsono Ono , Khotimah Siti 
Published: September 2019

Penelitian ini bertujuan untuk (1) mengetahui jumlah safety stock yang sudah ditetapkan oleh manajemen perusahaan apakah sudah optimal (2) mengetahui jumlah pembelian bahan baku yang optimal, dan mengetahui total biaya persediaan yang optimal, dan (3) mengetahui waktu pemesanan kembali (reorder point). Data yang dipelajari berupa data tentang (1) kebutuhan bahan baku tahun 2015 (2) biaya pemesanan setiap kali pesan tahun 2015 (3) harga faktur bahan yang dibeli tahun 2015 (4) biaya penyimpanan variabel tahun 2015. Metode penelitiaan yang digunakan adalah (1) Metode Economic Order Quantity (EOQ) (2) Metode Safety Stock (SS) (3) Metode Reorder Point (ROP). Dengan diperoleh kesimpulan sebagai berikut : (1) Besarnya safety stock ditentukan oleh perusahaan sebesar 30% dari kebutuhan bulan berikutnya (2) Kuantitas pembelian optimal bahan baku alcohol sebesar 15,6 ton, dengan frekuensi pembelian sebanyak 12 kali, bahan baku Texapon N-70 sebesar 10 ton, dengan frekuensi pembelian sebanyak 8 kali, bahan baku Whimol 15 sebesar 9 ton, dengan frekuensi pembelian sebanyak 7 kali, bahan baku Euperlan PK771 sebesar 7 ton, dengan frekuensi pembelian sebanyak 5 kali, dan bahan baku Edenor C12-99 MY sebesar 7 ton, dengan frekuensi pembelian sebanyak 5 kali, dan besarnya total biaya persediaan untuk 5 (lima) jenis bahan baku utama sebesar 3.708.967.727. (3) Titik pemesanan kembali untuk bahan baku alcohol dilakukan apabila mencapai 14 ton, bahan baku Texapon mencapai 5.8 ton, bahan baku Whimol 15 mencapai 4.6 ton, bahan baku Euperlan PK771 mencapai 2.3 ton , dan bahan baku Edenor C12-99 MY mencapai 3.35 ton. Berdasarkan kesimpulan diatas, maka penulis memberikan saran kepada perusahaan PT. Martina Berto Tbk. Agar mempertimbangkan penggunaan metode EOQ dan kapan perusahaan harus melakukan pemesanan kembali, agar pengendalian persediaan yang efektif dan efisien dapat tercapai.
Model Hubungan Citra Merek, Perpsepsi Kualitas, Harga dan Intensi Pembelian Konsumen
Authors: Hendryadi Hendryadi , Purnamasari Diana 
Published: September 2019

Penelitian ini menguji hubungan antara citra merek, persepsi kualitas, dan harga pada intensi pembelitian produk pafum merek X. Secara khusus, peran kualitas dan harga ditempatkan sebagai mediator pada hubungan citra merek dengan intensi pembelian. Data dikumpulkan melalui penyebaran kuesioner dengan metode convenience sampling. Sebanyak 117 pelanggan dari tiga supermarket di Jakarta dijadikan responden. Analisis data menggunakan PLS-SEM untuk menguji hipotesis yang diajukan. Hasil empiris menunjukkan bahwa citra merek secara signifikan dan positif berpengaruh terhadap persepsi kualitas dan harga. Citra merek, kualitas, dan harga adalah tiga faktor yang secara langsung mempengaruhi intensi pembelian. Pengujian model mediasi menunjukkan bahwa harga terbukti sebagai mediator hubungan citra merek dengan intensi pembelian, sedangkan persepsi kualitas tidak signifikan. Penelitian ini terbatas pada perilaku pembelian produk parfum sehingga riset mendatang dapat memperluas analisis pada produk yang berbeda.
Glutathione Reductase Promotes Fungal Clearance and Suppresses Inflammation during Systemic Candida albicans Infection in Mice
Authors: Kim Victoria Y. , Batty Abel , Li Jinhui , Kirk Sean G. , Crowell Sara A. , Jin Yi , Tang Juan , Zhang Jian , Rogers Lynette K. , Deng Han-Xiang , Nelin Leif D. , Liu Yusen 
Published: September 2019

Abstract
Glutathione reductase (Gsr) catalyzes the reduction of glutathione disulfide to glutathione, which plays an important role in redox regulation. We have previously shown that Gsr facilitates neutrophil bactericidal activities and is pivotal for host defense against bacterial pathogens. However, it is unclear whether Gsr is required for immune defense against fungal pathogens. It is also unclear whether Gsr plays a role in immunological functions outside of neutrophils during immune defense. In this study, we report that Gsr−/− mice exhibited markedly increased susceptibility to Candida albicans challenge. Upon C. albicans infection, Gsr−/− mice exhibited dramatically increased fungal burden in the kidneys, cytokine and chemokine storm, striking neutrophil infiltration, histological abnormalities in both the kidneys and heart, and substantially elevated mortality. Large fungal foci surrounded by massive numbers of neutrophils were detected outside of the glomeruli in the kidneys of Gsr−/− mice but were not found in wild-type mice. Examination of the neutrophils and macrophages of Gsr−/− mice revealed several defects. Gsr−/− neutrophils exhibited compromised phagocytosis, attenuated respiratory burst, and impaired fungicidal activity in vitro. Moreover, upon C. albicans stimulation, Gsr−/− macrophages produced increased levels of inflammatory cytokines and exhibited elevated p38 and JNK activities, at least in part, because of lower MAPK phosphatase (Mkp)-1 activity and greater Syk activity. Thus, Gsr-mediated redox regulation is crucial for fungal clearance by neutrophils and the proper control of the inflammatory response by macrophages during host defense against fungal challenge.
Epidemiology of cystic fibrosis respiratory pathogens isolated at a South African Hospital, 2006–2010
Authors: Chibabhai Vindana , Lowman Warren 
Published: September 2019

Background: The epidemiology of cystic fibrosis (CF) associated pathogens other than Pseudomonas aeruginosa in the South African cystic fibrosis population has not been previously described.Methods: A retrospective review of respiratory cultures taken from cystic fibrosis clinic patients at the Charlotte Maxeke Johannesburg Academic Hospital from 2006 to 2010 was performed.Results: During the study period, Pseudomonas aeruginosa, Stenotrophomonas maltophilia, Burkholderia cepacia complex and Candida albicans prevalence remained stable, Aspergillus fumigatus increased from 8% to 20% (p = 0.0132); Staphylococcus aureus decreased from 66% to 50% (p = 0.0243) and Haemophilus influenzae decreased from 13% to 3% (p = 0.0136). There were significant antimicrobial susceptibility changes to meropenem (p 0.0001) amongst P. aeruginosa isolates and cloxacillin (p 0.0001) amongst S. aureus isolates. Prevalence of most bacterial pathogens appeared to increase with increasing age.Conclusion: The findings of this study illustrate the epidemiology of CF associated respiratory pathogens and the trends in prevalence and susceptibility patterns over a 5-year period.
Risk factors associated with nosocomial infections in the Neonatal Intensive Care Unit at Mahatma Gandhi Memorial hospital between 2014 and 2015
Authors: Rameshwarnath Sharita , Naidoo Saloshni 
Published: September 2019

Background: Nosocomial infections are one of the main causes of neonatal morbidity and mortality in low- and middle-income countries. The neonatal intensive care unit is a suitable environment for disseminating infections. The aim of this study was to identify risk factors associated with having a nosocomial infection in the neonatal intensive care unit at Mahatma Gandhi Memorial hospital between 2014 and 2015.Methods: An observational, analytical case-control study was conducted at the neonatal intensive care unit at Mahatma Gandhi Memorial hospital in 2017 following ethical approval (BE336/16). A retrospective review of medical records for a sample size of 144 cases and 144 matched controls from 2014 to 2015 was analysed. Descriptive statistics were presented and multivariate conditional logistic regression was used to determine associations between the independent variables and having a nosocomial infection.Results: A total of 144 neonates developed nosocomial infections as proven by positive cultures with Klebsiella pneumoniae being most frequent (n = 60; 41.67%). On multivariate logistic regression analysis, multiple deliveries, low birth weight, respiratory distress, prematurity, neonatal jaundice, hyaline membrane disease, the use of total parenteral nutrition, blood transfusion and surfactant administration, immediate use of oxygen and intravenous fluid and central line insertion were significantly associated with having a nosocomial infection (p ≤ 0.001).Conclusion: Neonatal-related factors and treatment modalities were identified as factors that increased the risk for nosocomial infections. A review of treatment modalities and related infection prevention and control in neonatal management are the key to prevention, early detection and management of nosocomial infections.
Influence of vaccination status and clinical, seasonal and sociodemographic factors on rotavirus prevalence in KwaZulu-Natal, South Africa
Authors: Asowata Osaretin E. , Ashiru Olubisi T. , Mahomed Saajida , Sturm A. Willem , Moodley Prashini 
Published: September 2019

Human rotavirus infection is the leading cause of diarrhoea in infants and young children worldwide. In South Africa, diarrhoea is a major cause of childhood morbidity and mortality in children less than five years old, and before the vaccine was introduced rotavirus had been reported as causing one-third of all diarrhoeal related hospital admissions. This study assessed factors influencing the prevalence of rotavirus in children aged five years and under in KwaZulu-Natal, South Africa between June 2014 and June 2015. In addition, genotypes of the rotaviruses were determined. A stool specimen was collected from children presenting with diarrhoea to a regional hospital. Clinical, vaccination status, seasonal and sociodemographic information was collected using a structured questionnaire. ELISA (enzyme linked immunosorbent assay) was performed to detect rotavirus antigen in the stool. Rotavirus from selected positives specimens were genotyped using RT–PCR (reverse transcriptase polymerase chain reaction). The data were analysed using SPSS. In total, 365 stool specimens were collected. Rotavirus antigen was detected in 83 (23%) patients. The prevalence of rotavirus was not affected by vaccination status (p = 0.3; OR 1.5; CI 0.7–3.1), HIV status (p = 0.2; OR 0.6; CI 0.2–1.5), breastfeeding (p = 0.9; OR 1.1; CI 0.5–2.5) and administration of anti-helminth treatment (p = 0.6; OR 0.8; CI 0.3–1.9). The highest rotavirus prevalence was observed in the winter season (p 0.001; OR 43.3; CI 14.9–125.0). The G9P[8] was the most prevalent genotype (21%) followed by G9P[4] (14%). Rotavirus remains a major contributor to childhood diarrhoeal aetiology and hospitalisation in KwaZulu-Natal. Further investigation is needed to better understand the key drivers of rotavirus infection despite a successful vaccination programme in South Africa.
Antimicrobial Use and Misuse at the End of Life: A Retrospective Analysis of a Treatment Escalation/Limitation Plan
Authors: Wilder-Smith Adrian , Gillespie Thomas , Taylor D Robin 
Published: September 2019

Background Antimicrobial treatment is common at end of life. A treatment escalation/limitation plan (TELP) offers the opportunity to avoid non-beneficial treatment in critically ill patients. Our aim was to evaluate antimicrobial prescribing in terminally ill patients, and assess whether it was modified using a TELP. Methods Appropriateness of antimicrobial treatment was audited using a priori criteria in 94 consecutive hospital deaths. Prescribing in patients whose death was expected/unexpected, and who had a TELP with/without a ‘ceiling’ for antimicrobials, were compared. Results Twenty three of 94 patients (24.5%) were receiving antimicrobials at time of death. This was not influenced by evidence of infection or whether death was expected. The use of a TELP (n = 81) with an antimicrobial ‘ceiling’ (28 with, 53 without) was associated with a significant reduction in antimicrobials administered (28.6% vs 81.1%; p < 0.0005). Conclusions Many complex factors contribute to antimicrobial misuse at end of life. An appropriately constructed TELP reduces inappropriate prescribing.
Quality Criteria for Core Medical Training: A Resume of Their Development, Impact and Future Plans
Authors: Armstrong Miriam , Black David , Miller Alastair 
Published: September 2019

Background In 2015 the Joint Royal Colleges of Physicians Training Board (JRCPTB), acting on behalf of the three UK Royal Colleges of Physicians, launched a set of quality criteria designed to improve the educational experience of Core Medical Trainees. Methods The criteria were developed with key stakeholders from Core Medical Training (CMT) and monitored via the General Medical Council's annual National Training Survey. This paper describes the development, implementation and impact of these criteria, which have been implemented by UK postgraduate schools of medicine since 2015. Results There were trainee-reported improvements from baseline (2015-18) in at least eight out of the 13 core criteria measured. Conclusions The results demonstrate that a coordinated UK-wide approach to quality improvement, focused on a specific set of clearly defined and measurable outcomes that galvanise trainer engagement, can lead to greater trainee satisfaction in a demanding area of medicine without significant additional resources.
Fungal Infection: A Hidden Enemy in Diabetic Foot Ulcers
Authors: Sanniyasi Saravanan , Balu Jagan , Narayanan Cunnigaiper Dhanasekharan 
Published: September 2019

ABSTRACT
Diabetic foot ulcers are on the rise and increasingly associated with amputations. Fungal infections have recently been implicated in the nonhealing nature of these wounds. One hundred five patients treated as in-patients with nonhealing diabetic ulcers in a tertiary care hospital were included in this prospective study. Wound swabs and deep tissue biopsies were taken from these ulcers for fungal stain and culture and bacterial culture. Once the fungal stain or the culture study is positive, oral Fluconazole was started. Nineteen patients grew fungus in the ulcer, commonest species being Candida tropicalis (10.5%). The most common bacterial organism isolated with fungal infection is Pseudomonas followed by Enterococcus. Patients on prolonged antibiotic therapy showed statistically significant increase in fungal infection. Patients who underwent amputation within 15 days of admission were higher in fungal culture positive group, due to progression of ulcer in spite of antibiotic therapy. There is a definite correlation between incidence of amputation and fungal infection in whom antifungal therapy was not started, though not statistically significant. Fourteen patients, who did not undergo amputation, had faster wound healing and lesser progression of disease, with none of them requiring amputation after initiating antifungal therapy. Our study reveals that there is a definite relation between fungal infections and nonhealing nature of diabetic ulcers. Further randomized trials are necessary to substantiate this finding.

How to cite this article
Sanniyasi S, Balu J, Narayanan CD. Fungal Infection: A Hidden Enemy in Diabetic Foot Ulcers. J Foot Ankle Surg (Asia-Pacific) 2015;2(2):74-76.
Achilles Tendon Rupture Secondary to Kite String (Manja) Injury: A Rare Etiology seen in Two Cases
Authors: Bagaria Vaibhav , Nemade Amit , Joshi Nilesh 
Published: September 2019

ABSTRACT
Achilles tendon is the strongest and the thickest tendon of the human body. Due to its superficial location and stress, it has to face due to loading, the tendon is susceptible to injuries and ruptures. This is aggravated due to the precarious blood supply in the region and also age-related changes that occur in the tendon. Of the specific causes age-related and steroid induced tendinosis and sports injuries are the commonest mechanism of injury. Kite playing is a very common sport in the Indian subcontinent, which involves the use of a string (manja) often coated with powdered glass to fly the kite. Many grievous injuries are reported due to its use especially in two wheeler riders. However, to the best of our knowledge a kite thread injury causing Achilles tendon tear due to direct impact has so far not been reported. In this case series, we describe two cases that had such injury and a brief note on specifics of management of this case is described.

How to cite this article
Bagaria V, Nemade A, Joshi N. Achilles Tendon Rupture Secondary to Kite String (Manja) Injury: A Rare Etiology seen in Two Cases. J Foot Ankle Surg (Asia-Pacific) 2015;2(2):90-93.
Ethibond Suture Granuloma following Tibialis Anterior Tendon Transfer Mimicking Osteomyelitis of Foot
Authors: Gopinathan Nirmal Raj , Saibaba Balaji , Santhanam Siva Swaminathan , Kanojia Rajendra Kumar 
Published: September 2019

ABSTRACT
Tibialis anterior tendon transfer is routinely done for the correction of dynamic supination deformity of foot in children with congenital talipes equinovarus (CTEV). Surgeons commonly make use of a nonabsorbable suture—‘ethibond number 2’ for anchoring the transferred tendon to the new recipient site. We would like to report a case of suture granuloma following tibialis anterior tendon transfer in a 4 years old child, presenting with a swelling and discharging sinus clinically mimicking osteomyelitis. Unlike osteomyelitis, the patient did not have fever or pain clinically, nor was any organism detected microbiologically. The clinical presentation and the successful management of the case have been described in detail along with relevant review of literature.

How to cite this article
Gopinathan NR, Dhillon MS, Saibaba B, Santhanam SS, Kanojia RK. Ethibond Suture Granuloma following Tibialis Anterior Tendon Transfer Mimicking Osteomyelitis of Foot. J Foot Ankle Surg (Asia-Pacific) 2015;2(2):97-100.