bluuebunny/crossref_metadata_2025_split huggingface dataset:
Late Presentation of a Retained Stingray Spine in the Plantar Medial Hindfoot
Authors: Falk David P. , Metikala Sreenivasulu , Lopez Viviana Serra , Stein Matthew , Mahmoud Karim , Chao Wen 
Published: August 2019

In the United States, approximately 2000 stingray injuries occur annually. The majority of reports on stingray injuries to the foot and ankle reflect acute injuries. Delayed presentation after stingray injury to the foot and ankle has not been reported. We present a case of a 29-year-old female who sustained a stingray injury to the left plantar medial hindfoot 14 months prior to presenting to our clinic with new-onset posteromedial ankle redness and swelling along the tarsal tunnel. Magnetic resonance imaging (MRI) revealed multiple linear foreign bodies at the quadratus plantae and tarsal tunnel. The patient underwent operative exploration with removal of multiple retained stingray spines. At her most recent follow-up at 3 months, she was able to resume her usual activities. Level of Evidence: Level V, case report.
Microvascular endothelial function and primary open angle glaucoma
Authors: Mudassar Imran Bukhari Syed , Yew Kiu Kwong , Thambiraja Rajasunthari , Sulong Sarina , Ghulam Rasool Aida Hanum , Ahmad Tajudin Liza-Sharmini 
Published: August 2019

Purpose: To determine the role of microvascular endothelial dysfunction as risk factor for primary open angle glaucoma. Methods: A cross-sectional study was conducted involving 114 Malay patients with POAG seen at the eye clinic of Hospital Universiti Sains Malaysia. Patients aged between 40 and 80 years who were diagnosed with other types of glaucoma, previous glaucoma filtering surgery or other surgeries except uncomplicated cataract surgery and pterygium surgery were excluded. A total of 101 patients who were followed up for dry eyes, age-related cataracts or post cataracts extraction surgery were recruited as control subjects. Those with family history of glaucoma or glaucoma suspect were excluded. Microvascular endothelial function was assessed using laser Doppler fluximetry and the process of iontophoresis. Iontophoresis with acetylcholine (ACh) and sodium nitroprusside (SNP) was used to measure microvascular endothelium-dependent and endothelium-independent vasodilatations, respectively. Results: In general, POAG patients demonstrated lower ACh% and AChmax values compared with controls. There was significant difference in microvascular endothelial function [ACh%: mean, 95% confidence interval = 503.1 (378.0, 628.3), and AChmax: mean, 95% confidence interval = 36.8 (30.2, 43.5)] between primary open angle glaucoma cases ( p < 0.001) and controls [ACh%: mean, 95% confidence interval = 1378.4 (1245.4, 1511.3), and AChmax: mean, 95% confidence interval = 79.2 (72.1, 86.2)]; this difference remained significant even after controlling for potential confounders. Similar difference was also found in SNP% and SNPmax between POAG and controls ( p < 0.001). Age and diastolic blood pressure were inversely correlated with microvascular endothelial function. Conclusion: There was an impairment of microvascular endothelial function and endothelial-independent vasodilatation in POAG patients. Microvascular endothelial function is a potential risk factor for POAG.
Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis
Authors: Müller-Calleja Nadine , Hollerbach Anne , Ritter Svenja , Pedrosa Denise G. , Strand Dennis , Graf Claudine , Reinhardt Christoph , Strand Susanne , Poncelet Philippe , Griffin John H. , Lackner Karl J. , Ruf Wolfram 
Published: August 2019

AbstractAntiphospholipid antibody syndrome is caused by antiphospholipid antibodies (aPLs) that cause thrombosis and pregnancy loss. In a Plenary Paper, Müller-Calleja et al dissect the complex and multifaceted mechanism by which aPLs induce thrombosis through priming of monocytes and disruption of the balance of tissue factor activation and inhibition.
Radiographic lung volumes predict progression to COPD in smokers with preserved spirometry in SPIROMICS
Authors: Arjomandi Mehrdad , Zeng Siyang , Barjaktarevic Igor , Barr R. Graham , Bleecker Eugene R. , Bowler Russell P. , Buhr Russell G. , Criner Gerard J. , Comellas Alejandro P. , Cooper Christopher B. , Couper David J. , Curtis Jeffrey L. , Dransfield Mark T. , Han MeiLan K. , Hansel Nadia N. , Hoffman Eric A. , Kaner Robert J. , Kanner Richard E. , Krishnan Jerry A. , Paine Robert , Peters Stephen P. , Rennard Stephen I. , Woodruff Prescott G. 
Published: August 2019

The characteristics that predict progression to overt chronic obstructive pulmonary disease (COPD) in smokers without spirometric airflow obstruction are not clearly defined.We conducted apost hocanalysis of 849 current and former smokers (≥20 pack–years) with preserved spirometry from the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) cohort who had baseline computed tomography (CT) scans of lungs and serial spirometry. We examined whether CT-derived lung volumes representing air trapping could predict adverse respiratory outcomes and more rapid decline in spirometry to overt COPD using mixed-effect linear modelling.Among these subjects with normal forced expiratory volume in 1 s (FEV1) to forced vital capacity (FVC) ratio, CT-measured residual volume (RVCT) to total lung capacity (TLCCT) ratio varied widely, from 21% to 59%. Over 2.5±0.7 years of follow-up, subjects with higher RVCT/TLCCThad a greater differential rate of decline in FEV1/FVC; those in the upper RVCT/TLCCTtertile had a 0.66% (95% CI 0.06%–1.27%) faster rate of decline per year compared with those in the lower tertile (p=0.015) regardless of demographics, baseline spirometry, respiratory symptoms score, smoking status (formerversuscurrent) or smoking burden (pack–years). Accordingly, subjects with higher RVCT/TLCCTwere more likely to develop spirometric COPD (OR 5.7 (95% CI 2.4–13.2) in upperversuslower RVCT/TLCCTtertile; p<0.001). Other CT indices of air trapping showed similar patterns of association with lung function decline; however, when all CT indices of air trapping, emphysema, and airway disease were included in the same model, only RVCT/TLCCTretained its significance.Increased air trapping based on radiographic lung volumes predicts accelerated spirometry decline and progression to COPD in smokers without obstruction.
Brain ectopic tissue in sacrococcygeal region of a child, clinically mimicking sacrococcygeal teratoma: a case report
Authors: Saadaat Ramin , Abdul-Ghafar Jamshid , Nasir Ahmed , Rahmani Soma , Hamidi Hidayatullah 
Published: August 2019

Abstract
Background
Mature brain heterotopic tissue in sacrococcygeal region is a very rare benign congenital abnormality of newborn. To date, only two cases of mature heterotopic brain tissue in the sacrococcygeal region is reported by literature. Heterotopic brain tissue in other areas such as lung, nose, face and retroperitoneal region are also rarely reported. Meanwhile, rather than brain heterotopic tissue in sacrococcygeal region, a case of adrenal gland heterotopic tissue in sacrococcygeal region also has been reported.

Case presentation
A 3.5 month-old male baby presented with history of sacrococcygeal mass since birth. Clinical examination of the child was good with no other problem. Sacrococcygeal region revealed an elevated round mass with no discharge. Computed tomography reported a large sacrococcygeal teratoma type-III arising from the sacrococcygeal region extending intra-abdominally to the level of L2 vertebral body. The mass was excised by the impression of sacrococcygeal teratoma (SCT). On gross examination, a gray-white irregular tissue fragment with 5 cm in greatest dimension was examined. Cut sections showed homogenous yellowish white appearance. Histological examination revealed solid fragments composed of mature neural tissue comprising glial cells and astrocytes with no other germ cell layer component.

Conclusion
Mature brain heterotopic tissue in sacrococcygeal area is a rare benign disease. Two ectopic brain tissue in sacrococcygeal region were previously also reported. Sacrococcygeal teratoma is the most common congenital tumor, but this current rare case of heterotopic brain tissue in sacrococcygeal region should also be in the differential diagnosis.
Structures and Electronic Properties of Diisopropylaminoborane Substituted with Highly Electron-Rich π-Conjugated Systems and Their Oxidized States
Authors: Yoshida Kohei , Suzuki Shuichi , Kozaki Masatoshi , Okada Keiji 
Published: August 2019

Abstract
We have designed and synthesized three kinds of diisopropylaminoboranes substituted with two electron-donating π-conjugated systems, 2a: bis(phenothiazinyl) 2b: bis(N-phenyldihydrophenazinyl), and 2c: bis(phenoxazinyl) derivatives, and investigated their structures and electronic properties including those of oxidized species. The structural analyses of 2a–c and 2a–c•+ indicated that the π-electronic systems composed of boron and three nitrogen atoms showed unique structural deformation by one-electron-oxidation. The structures of the neutral compounds were almost C2-symmetrical, indicating that the two donor π-electronic systems are almost identical. In contrast, the radical cationic compounds were not C2-symmetrical structures because the charges of the radical cations were localized on one of the electron donors. In addition, the B–N bonds directly bound to the radical cations were elongated; also, perpendicular arrangements between the p-orbital of boron and π-conjugated orbitals of the radical cations were observed. We also succeeded in observing the triplet state of 2b2(•+), which was categorized as a heteroatom analogue of the trimethylenemethane (TMM) π-electronic system, by means of electron-spin resonance (ESR) spectroscopy.
Activity Mapping of Children in Play Using Multivariate Analysis of Movement Events
Authors: ROCHA JOANA N. , BARNES CLAIRE M. , REES PAUL , CLARK CAIN T. , STRATTON GARETH , SUMMERS HUW D. 
Published: August 2019

ABSTRACT

Purpose
(i) To develop an automated measurement technique for the assessment of both the form and intensity of physical activity undertaken by children during play. (ii) To profile the varying activity across a cohort of children using a multivariate analysis of their movement patterns.

Methods
Ankle-worn accelerometers were used to record 40 min of activity during a school recess, for 24 children over five consecutive days. Activity events of 1.1 s duration were identified within the acceleration time trace and compared with a reference motif, consisting of a single walking stride acceleration trace, obtained on a treadmill operating at a speed of 4 km h−1. Dynamic time warping of motif and activity events provided metrics of comparative movement duration and intensity, which formed the data set for multivariate mapping of the cohort activity using a principal component analysis (PCA).

Results
The two-dimensional PCA plot provided clear differentiation of children displaying diverse activity profiles and clustering of those with similar movement patterns. The first component of the PCA correlated to the integrated intensity of movement over the 40-min period, whereas the second component informed on the temporal phasing of activity.

Conclusions
By defining movement events and then quantifying them by reference to a motion-standard, meaningful assessment of highly varied activity within free play can be obtained. This allows detailed profiling of individual children’s activity and provides an insight on social aspects of play through identification of matched activity time profiles for children participating in conjoined play.
DIRITTI FONDAMENTALI E DIRITTI UMANI: IL CONTRIBUTO DELLA TEORIA DEI SISTEMI SOCIALI. PROSPETTIVE DI INDAGINE
Authors: Lima Fernando Rister de Sousa , Finco Matteo 
Published: August 2019

Il presente articolo analizza la natura e la funzione dei diritti fondamentali e umani dalla prospettiva della teoria dei sistemi sociali, sviluppata dal sociologo Niklas Luhmann alla fi ne del XX secolo. A partire dal contributo dell’autore tedesco e di altri studiosi, verrà messo in evidenza il potenziale che la teoria detiene riguardo al tema in oggetto, avanzando proposte su prospettive di ricerca future. L’ipotesi è che una teoria secondo cui la società è fatta di comunicazione, e non di esseri umani, può aprire spazi di riflessione inediti e mettere il luce la funzione latente dei diritti fondamentali e umani: oltre che valori di ispirazione umanistica, essi rappresenterebbero lo strumento attraverso cui la società stessa costituisce gli esseri umani nella triplice veste di individui, soggetti, persone.
RELAÇÕES LABORAIS E LIMITES JURÍDICOS AO ACESSO E USO DAS INFORMAÇÕES GENÉTICAS DO EMPREGADO
Authors: Araújo Ana Thereza Meirelles , Pessanha Vanessa Vieira 
Published: August 2019

Artigo destinado à análise dos limites jurídicos conformadores do uso da informação genética no âmbito das relações laborais. Como premissa, partiu-se de uma análise panorâmica sobre o acesso e o uso da informação contida no DNA conforme os padrões atuais da Ciência, considerando os pretensos benefícios e os riscos agregados. Como objetivo central da pesquisa, buscou-se identifi car as balizas previstas na legislação em vigor que fundamentam a necessidade de contingenciar o uso da informação genética pelo empregador nas relações pré-contratuais, contratuais e pós-contratuais de trabalho. O estudo em voga tem como justificativa a necessidade de sopesar adequadamente a proteção ao trabalhador em condição de vulnerabilidade face à possibilidade de que sua informação genética possa ser arbitrariamente acessada e utilizada, culminando na violação de conteúdos constitucionalmente fundamentais como a igualdade e a intimidade. Optou-se pela perspectiva metodológica hipotético-dedutiva, tendo em vista adequar-se melhor ao objetivo apontado, a partir da construção de pesquisa de natureza bibliográfica.
Role of scalp hypothermia in patients undergoing minimally invasive evacuation of hypertensive cerebral hemorrhage
Authors: Zhang Yueling , Song Ling , Zhao Jianfen 
Published: August 2019

Objective: Hypertensive intracerebral hemorrhage (HICH) is one of the common multiple diseases in neurology. Patients with severe HICH have high risk of disability and poor prognosis.
Methods: In order to explore the clinical effect of mild hypothermia combined with micro-traumatic evacuation of cerebral hemorrhage in the treatment of severe HICH, 136 patients with severe HICH were selected and divided into control group and study group using random number table method, 68 each group. The control group was treated with micro-traumatic evacuation of cerebral hemorrhage on the basis of conventional symptomatic treatment, while the study group was treated with mild hypothermia combined with micro-traumatic evacuation of cerebral hemorrhage on the basis of conventional symptomatic treatment. After treatment, the two groups were followed up for eight weeks.
Results: The overall effective rate, residual hematoma volume, rebleeding rate, National Institute of Health stroke scale (NIHSS) score, Barthel index score and incidence of adverse reactions after treatment were observed and compared. The overall effective rate of the study group was 89.7%, which was significantly higher than that of the control group (67.6%). The mortality rate of the study group was 3.0%, which was significantly lower than that of the control group (14.7%, P<0.05). The residual hematoma volume and rebleeding rate of the study group were significantly lower than those of the control group (P<0.05). Before treatment, the NIHSS score and Barthel index score of the two groups had no significant differences (P>0.05). After treatment, they were improved, and the improvement of the study group was more significant (P<0.05). The incidence of adverse reactions in the study group was 10.0%, which was significantly lower than that in the control group (36.0%, P<0.05).
Conclusion: Mild hypothermia in combination with micro-traumatic evacuation of cerebral hemorrhage has significant clinical effect in the treatment of severe HICH. It can significantly improve neurological function and quality of life, causing few adverse reactions. Its clinical application value is high.
doi: https://doi.org/10.12669/pjms.35.5.593
How to cite this:Zhang Y, Song L, Zhao J. Role of scalp hypothermia in patients undergoing minimally invasive evacuation of hypertensive cerebral hemorrhage. Pak J Med Sci. 2019;35(5):1451-1455. doi: https://doi.org/10.12669/pjms.35.5.593
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Correlates of respiratory admissions frequency in patients with obstructive lung diseases: coping styles, personality and anxiety
Authors: Tabała Klaudia , Wrzesińska Magdalena , Stecz Patryk , Mąkosa Grzegorz , Kocur Józef 
Published: August 2019

Cel pracyAstma oskrzelowa (AO) i przewlekła obturacyjna choroba płuc (POChP) są związane z ogromnym obciążeniem finansowym dla budżetu oraz opieki zdrowotnej na świecie. Cechy osobowości, preferowane sposoby radzenia sobie ze stresem oraz poziom lęku wpływają na funkcjonowanie ludzi chorych. Celem badania była ocena związku pomiędzy tymi zmiennymi a częstością pobytów w szpitalu i wizyt w poradni specjalistycznej u chorych z przewlekłymi chorobami układu oddechowego.MetodaSto osób chorujących na astmę oskrzelową i POChP zostało przebadanych testami psychologicznymi: Inwentarzem Osobowości NEO-FFI, Inwentarzem Stanu i Cechy Lęku (STAI), Inwentarzem do Pomiaru Radzenia Sobie ze Stresem Mini-COPE. Została także wykorzystana ankieta socjodemograficzna.WynikiWykazano zależność pomiędzy częstością wizyt w szpitalu a neurotycznością (korelacja pozytywna). Liczba wizyt w poradni korelowała dodatnio z poziomem sumienności, korzystaniem ze wsparcia emocjonalnego oraz ujemnie z zaprzestawaniem działań.WnioskiUzyskane wyniki mogą wskazywać na potrzebę objęcia osób z chorobami układu oddechowego działaniami psychoterapeutycznymi służącymi budowaniu bardziej konstruktywnemu funkcjonowaniu, zmniejszeniu niepokoju, zwiększaniu poczucia kontroli.
The holistic management of fatigue within palliative care
Authors: Dean Antonia 
Published: August 2019

Background: Fatigue is a common symptom experienced by people with cancer and other long-term, non-malignant conditions. It can be disease-related or caused by treatments such as chemotherapy or radiotherapy. Patients frequently report this as a distressing symptom and, while some international guidelines for its management exist, evidence suggests that these are not always implemented. Method: This article reviews the evidence basis for fatigue management, looking at exercise, education, psychological interventions, complementary therapies and pharmacological therapy, and finds that a one-size fits all approach to fatigue management is unrealistic. Findings: Research appears to support different interventions at various points in the disease trajectory and this is of importance for service design as palliative care is increasingly introduced earlier in the patient's pathway. Conclusion: Although the body of research is growing, management of fatigue caused by non-malignant conditions remains poorly evidenced, making comprehensive recommendations for these patient groups even more challenging.
Thinking about strengths in end-of-life nursing practice: the case of intensive care unit nurses
Authors: Vanderspank-Wright Brandi , Wright David Kenneth , McMillan Kim 
Published: August 2019

Background: The intensive care unit (ICU) is a care context that is sometimes described as being unconducive to the values and ideals of a good death in end-of-life care. Such assumptions render the ICU emblematic of a troubling discourse about end-of-life care in this clinical context. Aim: To stimulate a reflective examination of intensive care nursing practice with respect to end-of-life care. Methods: The work of contemporary nursing scholar Laurie Gottlieb is used to perform a strengths-based relational ethical examination of previously published literature that describes critical care nurses' experiences of providing end-of-life care in the ICU. Findings: This literature suggests that the relational ethical value of authentic engagement, which is fundamental to the disciplinary ethos of expert palliative care nursing, is reflected in the everyday practice of intensive care nurses whose patients die while under their care. Conclusion: A strengths-based approach can make visible the relational ethical practice of critical care nurses who care for dying patients and their families in the ICU.
Cómo argumentar con coherencia
Authors: Gascón José Ángel 
Published: August 2019

When disagreements arise about the quality of arguments, arguers frequently rely on coherence. Argumentative coherence is mainly manifested in accusations of incoherence and in the production of analogies. With the help of the elements of warrant and of rebuttals in Toulmin's model, it is possible to give a first analysis of this notion.
Experimental investigation on the effect of drill quality on the performance of bone drilling
Authors: Alam Khurshid , Piya Sujan , Al-Ghaithi Ahmed , Silberschmidth Vadim 
Published: August 2019

Abstract
Bone drilling is a well-known process in operative fracture treatment and reconstructive surgery. The cutting ability of the drill is lost when used for multiple times. In this study, the effect of different levels of drill wear on bone temperature, drilling force, torque, delamination around the drilling region and surface roughness of the hole was investigated using a series of experiments. Experimental results demonstrated that the wear of the drill is strongly related to the drilling force, torque, temperature and surface roughness of the drilled hole. Statistical analysis was performed to find the effect of various factors on multiple response variables in the bone drilling process. The favorable conditions for bone drilling are obtained when feed rate, drill speed and the roughness of the cutting edge of the drill were fixed at 30 mm, 2000 rpm and up to 2 mm, respectively. Further, analysis of variance (ANOVA) was performed to determine the factor with a significant impact on the response variables. F-test and p-value indicated that the feed rate had the highest effect on grey relational grade followed by the roughness of the drill. This study suggests that the sharp drill along with controlled drilling speed and feed rate may be used for safe and efficient surgical drilling in bone.
The art of narrative – narrative as art: Sameness or difference?
Authors: Skalin Lars-Åke 
Published: August 2019

Abstract
This paper is a critique of narratology’s generality thesis and especially focused on a corollary of that thesis, the “sameness premise”. It says that all objects designated by the noun “narrative”, whether actual, possible, or fictional, are defined by some basic intrinsic properties. This goes for ordinary informative telling of events as well as for literary art, such as novels and short stories. The latter assumption is rejected by me and theorists taking up a “difference premise” instead. Literary art should not be included within a general category of narrative. It would be more correct to regard it as sui generis, since it manifests a system quite different from and incompatible with narrative as this system is defined by standard narratology. For example, ordinary narrative accounts display logically a two-place relation between the denoting signs and the denoted contents (events); while the artistic representations produced by literary art and other art-forms do not denote anything outside themselves– the relation between signs and content is one-place. I discuss this theoretic problem from two sources: modern narratology in conflict with artistic/aesthetic theory and the mimesis-debate in Greek antiquity between Plato and Aristotle, where Plato is advocating a sameness and Aristotle a difference premise.