bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case of intraoperative detection of a central venous catheter in azygos vein arch during esophageal cancer surgery
Authors: Murakawa Katsuhiko , Ono Koichi , Yamamura Yoshiyuki 
Published: November 2024

Abstract
Background
Central venous catheter (CVC) is often used in the perioperative management of esophageal cancer. The position of the CVC tip has been reported to shift with body positioning and, although infrequent, may traverse into the azygos vein arch. Herein, we describe a case where a migrated CVC tip in the azygous vein arch was identified during esophageal cancer surgery, preventing CVC dissection concurrent with azygous vein arch resection.

Case presentation
A 65-year-old man was diagnosed with advanced esophageal cancer and was referred to our department for surgery after undergoing neoadjuvant chemotherapy. He underwent robot-assisted subtotal esophagectomy, followed by gastric conduit reconstruction via the posterior sternal route. Thoracic manipulation was performed with the patient in the prone position. During the surgery, a foreign body was found in the azygos vein arch, indicating that a central venous catheter had inadvertently entered the azygos vein arch. The catheter was retracted by 5 cm, and after confirming that no catheter remained in the azygos arch, the azygos vein arch was separated using an autosuture device.

Conclusions
Central venous catheter migration can occur in a various vessels. During prone esophageal cancer surgery, elevating the right upper extremity may alter the catheter tip’s position from its the preoperative position. CVC amputation should be observed because the azygos vein arch is often amputated to facilitate upper mediastinal dissection during esophageal cancer surgery.
Effect of stabilizers on the detection of swine influenza A virus (swIAV) in spiked oral fluids over time
Authors: Grau K. , Lillie-Jaschniski K. , Graaf-Rau A. , Harder T. , Eddicks M. , Zöls S. , Zablotski Y. , Ritzmann M. , Stadler J. 
Published: November 2024

Abstract
Background
Aggregated samples such as oral fluids (OFs) display an animal friendly and time and cost-efficient sample type for swine Influenza A virus (swIAV) monitoring. However, further molecular and biological characterization of swIAV is of particular significance. The reportedly inferior suitability of aggregated samples for subtyping of swIAV presents a major drawback compared to nasal swabs, still considered the most appropriate sample type for this purpose (Garrido-Mantilla et al. BMC Vet Res 15(1):61, 2019). In addition, the viral load in the original sample, storage conditions and characteristics of different swIAV strains might further compromise the eligibility of aggregated samples for molecular detection and subtyping. Therefore, the present study aimed to evaluate the suitability of stabilizing media to minimize the degradation of viral RNA and thus increase the detection and subtyping rate of swIAV by RT-qPCR in spiked OFs under different conditions (virus strain, storage temperature and viral load in the original sample) over a time span of 14 days.

Results
The use of stabilizing media in spiked OFs resulted in a significant higher probability to detect swIAV RNA compared to OFs without stabilizers (OR = 46.1, p < 0.001). In addition, swIAV degradation over time was significantly reduced in samples suspended with stabilizer (OR = 5.80, p < 0.001), in samples stored at 4 °C (OR = 2.53, p < 0.001) and in samples spiked with the avian derived H1N2 subtype (OR = 2.26, p < 0.01). No significant differences in swIAV RNA detection and degradation of swIAV RNA in spiked OFs over time were observed between the three different stabilizing media.

Conclusion
Addition of stabilizers and storage of samples under cooled conditions significantly improved detection and subtyping of swIAV in spiked OFs.
Investigating the association of mechanical restraint with somatic harmful outcomes: national register-based study
Authors: Baandrup Lone , Kruse Marie 
Published: November 2024

Background
Coercive measures to manage disruptive or violent behaviour are accepted as standard practice in mental healthcare, but systematic knowledge of potentially harmful outcomes is insufficient.

Aims
To examine the association of mechanical restraint with several predefined somatic harmful outcomes.

Method
We conducted a population-based, observational cohort study linking data from the Danish national registers from 2007 to 2019. The primary analyses investigated the association of mechanical restraint with somatic adverse events, using panel regression analyses (within-individual analysis) to account for repeated exposures and outcomes. Secondary between-group analyses were performed with a control group exposed to types of coercion other than mechanical restraint.

Results
The study population comprised 13 022 individuals. We report a statistically significant association of mechanical restraint with thromboembolic events (relative risk 4.377, number needed to harm (NNH) 8231), pneumonia (relative risk 5.470, NNH 3945), injuries (relative risk 2.286, NNH 3240) and all-cause death (relative risk 5.540, NNH 4043) within 30 days after mechanical restraint. Estimates from the between-group analyses (comparing the exposed group with a control group of 22 643 individuals) were non-significant or indicated increased baseline risk in the control group. A positive dose–response analysis for cardiac arrest, injury and death supported a causative role of mechanical restraint in the reported associations.

Conclusions
Although the observed absolute risk increases were small, the derived relative risks were non-negligible considering that less restrictive interventions are available. Clinicians and decision makers should be aware of the excess risk in future decisions on the use of mechanical restraint versus alternative interventions.
Impact of Exercise on the Course of Dermatomyositis: A Narrative Review of Recent Studies
Authors: Chawrylak Katarzyna , Kubas Maria , Krzemińska Katarzyna , Kuszneruk Julia , Kłusek Magdalena 
Published: November 2024

Introduction and Purpose: Dermatomyositis (DM) is a rare autoimmune inflammatory myopathy characterized by muscle weakness and distinctive skin manifestations, impacting both children and adults. This narrative review aims to examine the latest studies assessing the impact of physical activity on the course of dermatomyositis and determine which forms of exercise are beneficial for DM patients.

Methods: A comprehensive literature review was conducted using the PubMed and Google Scholar databases, focusing on articles published between 2018 and 2024.

State of Knowledge: The review identified consistent evidence supporting the safety and efficacy of exercise in DM patients. Exercise regimens, including resistance, aerobic, and stretching exercises, were found to improve muscle strength, aerobic capacity, and metabolic functions without increasing disease activity. Novel exercise approaches, such as blood flow restriction training and aquatic plyometric exercises, also showed promising results. However, the heterogeneity of the trials and small sample sizes highlight the need for larger, more diverse cohorts and long-term studies

Summary: The findings underscore the potential of structured exercise programs to enhance muscle strength, aerobic capacity, and overall physical function in DM patients. These improvements are achieved without exacerbating disease activity, highlighting the safety of exercise interventions. The review emphasizes the importance of incorporating physical activity into treatment plans for DM, advocating for personalized exercise prescriptions tailored to the unique inflammatory nature of idiopathic inflammatory myopathies (IIM).
Site Suitability Classification for Saturated Bioenergy Buffers and Area Estimates in the U.S. Midwest
Authors: Cacho Jules F. , Quinn John J. , Zumpf Colleen R. , Negri Cristina 
Published: November 2024

HighlightsSuitability criteria for saturated bioenergy buffer (SBB) sites were developed.A method to classify cropland areas as suitable SBB sites was demonstrated using public data.The criteria and method for classifying suitable SBBs were generally successful at U.S. Midwest sites.Areas were identified within U.S. Midwest states having the greatest potential for SBB implementation.Abstract.Nutrient loss from tile-drained, row-crop fields is a major component in the impact of agricultural production on surface water quality, because drain tiles provide a short-circuit for nutrient-rich drainage water to reach ditches and eventually downstream waterbodies (e.g., creeks, streams, rivers). Saturated buffers (SBs) help address the tile-drainage water quality problem, and incorporating bioenergy crops into SBs (saturated bioenergy buffers, or SBBs) could provide both environmental protection and an economic benefit to farmers. The objectives of this analysis were to: (1) develop a site suitability classification approach for rapid, cost-effective identification of SBB candidate sites; and, after validation, (2) use it to estimate the size of land in the U.S. Midwest considered suitable for SBB sites. The approach uses several biophysical parameters to identify sites that (1) are likely to be tile-drained, row-cropped agricultural land; (2) have conditions conducive for denitrification; and (3) have stable streambanks. Supporting data came from federally funded and maintained U.S. databases (e.g., Soil Survey Geographic Database). This classification approach was implemented in ArcGIS Desktop and validated using data from various SB field studies in the U.S. Midwest. This approach has proven to be robust because it identified SB sites considered to be either performing or promising in reducing nitrate losses in tile drainage water with an accuracy range of 57% to 63%. SBB candidate areas in the U.S. Midwest totaled up to 225,000 ha and 342,000 ha for buffer widths of 20 and 30 m, respectively. The proposed approach could assist in both local siting and regional-scale implementation of SBBs, which could significantly mitigate nitrate loss in tile-drained U.S. Midwest agricultural lands while providing other environmental benefits and economic incentives for farmers. Keywords: Biomass production, Multi-functional landscapes, Sustainable agricultural land management, Tile-drained agriculture, Water quality protection.
Mycetoma: A critical appraisal of educational content on YouTube
Authors: Pitua Ivaan , Raizudheen Raafidha , Namiiro Amelia Margaret , Apili Lorraine , Bongomin Felix 
Published: November 2024

Background
Mycetoma is a fungal neglected tropical disease. Accurate dissemination of information is critical in endemic areas. YouTube, a popular platform for health information, hosts numerous videos on mycetoma, but the quality and reliability of these videos remain largely unassessed.

Methods
We used modified DISCERN and Global Quality Score (GQS) for reliability and quality respectively. Video duration, views, likes, and comments were recorded. Spearman’s rank correlation and Mann-Whitney U tests were used to identify correlations between metrices and quality scores.

Results
We included 73 mycetoma-related YouTube videos were analyzed, the median GQS score was 4.00 ((IQR = 3.33–4.00), indicating generally high-quality content, while the median mDISCERN score was 3.00 (IQR = 3.00–3.00) reflecting moderate reliability. Videos produced by professionals had significantly higher scores compared to those from consumer-generated content (p < 0.001). A significantly positive correlation was observed between video duration and both GQS (r = 0.417, p < 0.001) and mDISCERN (r = 0.343, p = 0.003). However, views, likes and comments did not significantly correlate with video quality. Additionally, videos longer in duration (p < 0.001) and older in upload date (p = 0.014) had higher quality scores.

Conclusions
The study shows that mycetoma-related videos on YouTube are generally of high quality, with moderate reliability. This emphasizes the need for expert involvement in content creation and efforts to improve health information online.
The potential impact of COVID-19 vaccination on patients with immune thrombocytopenic purpura: A protocol for systematic review and meta-analysis
Authors: Li Yangyang , Kong Demin , Ding Yicheng , Wang Jinhuan 
Published: November 2024

Background
Immune thrombocytopenic purpura (ITP) is a disease characterized by a decrease in platelet count, which can be triggered by various factors, including viral infections and vaccination. With the widespread vaccination against COVID-19, concerns have arisen regarding a possible link between the vaccine and the exacerbation of ITP. This study aims to comprehensively evaluate the impact of COVID-19 vaccination on ITP patients, including associated risks and outcomes.

Methods
A comprehensive search will be conducted in multiple electronic databases (including PubMed, Web of Science, EMBASE, Cochrane Library, CNKI, Wan Fang, VIP, and CBM) to identify relevant studies. This study will include randomized controlled trials, cohort studies, case-control studies, and case series evaluating the impact of COVID-19 vaccination on ITP patients. The primary outcome measure is the change in platelet count, while secondary outcome measures include the occurrence of thromboembolic events, bleeding complications, ITP recurrence rate, impact of ITP exacerbation, and adverse events. Data will be summarized and analyzed using Review Manager Software (RevMan) V.5.4. In addition, subgroup analyses will be performed to explore potential sources of heterogeneity.

Results
It is anticipated that different types of COVID-19 vaccines may have varying impacts on ITP patients, leading to potential differences in outcomes. This study aims to comprehensively evaluate the potential impact of COVID-19 vaccination on ITP patients and provide reference for clinical decision-making.

Conclusions
The results of this systematic review and meta-analysis will provide crucial information on COVID-19 vaccination for ITP patients and clinicians, contributing to guiding vaccination decisions and monitoring potential impacts after vaccination.
Bridging disparity in knowledge and utilization of contraceptive methods among married couples in the pastoralist community of Fentale District, Eastern Ethiopia
Authors: Beyene Sena Adugna , Garoma Sileshi , Belachew Tefera 
Published: November 2024

Background
Despite progress in national reproductive health, pastoralist regions, including the Fentale District in Eastern Ethiopia, face challenges with limited contraceptive coverage due to gaps in understanding and adoption among couples.

Methods
This cross-sectional study of 1496 couples in Fentale District, Eastern Ethiopia, from October 1 to December 25, 2021, utilized multistage sampling. Data entered into EPI Data underwent analysis with SPSS (v23.0) and STATA (v14.0), employing descriptive statistics, bivariate analysis, and binary logistic regression to identify predictors of contraceptive knowledge.

Results
Of the 1496 couples, 93.8% (1404) participated in the survey. Significant educational disparities were observed, with 53.8% having no formal education, particularly among women (65.2%). Despite this, 80.2% of couples were aware of at least one family planning (FP) method, and 78.6% knew modern methods. The median knowledge of contraception methods was 3 for both genders. Men showed higher awareness of male (43.2%) and female condoms (17.4%) compared to women (31.8% and 6.0%). Overall, 27.4% of couples used contraception, with a significant gender difference: 41.2% of women and 13.5% of men. Modern contraceptives were used by 18.2% of couples, predominantly by women (34.8%). Binary logistic regression analysis indicated positive associations between contraceptive knowledge and education, bank account ownership, occupation, proximity to healthcare, and media exposure, while a nomadic-pastoralist lifestyle and specific treatment preferences showed negative associations.

Conclusion
The limited knowledge and utilization of family planning in the Fentale District stem from gaps in comprehension and disparities among couples. Factors influencing this situation include socio-demographic considerations, such as variations based on education, occupation, media exposure, bank account ownership, treatment preferences, and distance from healthcare facilities. This ensures that the interventions are having the desired effect and allows for adjustments as needed to promote family planning uptake.
Smokeless tobacco use and its associated factors among secondary school students of Rangeli Municipality of Morang district, Nepal
Authors: Rajbanshi Manish , Rajbanshi Rocky , Aryal Richa 
Published: November 2024

BackgroundThe tobacco epidemic is one of the biggest public health threats and the world’s leading cause of preventable death which is responsible for killing 8 million people every year. Adolescents are the vulnerable age group and are at greater risk of any tobacco use including smokeless tobacco (SLT) and nicotine addiction. Tobacco use at a young age increases the risk of various non-communicable diseases (NCDs) such as respiratory illness, asthma, chronic obstructive respiratory disease (COPD), reduced pulmonary function, and cancers. This study aimed to determine the prevalence of smokeless tobacco and its associated factors among secondary school students of grades 11 and 12 in Rangeli Municipality, Nepal.MethodologyA cross-sectional study was conducted among 355 students from the selected secondary schools. A self-administered questionnaire was used to collect the data. Data was cleaned and then exported to IBM SPSS Statistics 20 for analysis. Participants’ characteristics were described using frequencies, percentages, mean, and standard deviation. Multivariate logistic regression was conducted to determine the association between individual characteristics and prevalence of smokeless tobacco. All the tests were performed at a 95% Confidence Interval (CI) and a p-value less than 0.05.ResultsThe mean (±SD) age of the participants was 18.0±1.3 years. Most participants were female (61.1%). The majority of the participants were from grade 11 (58.3%), government schools (60%), and nuclear families (64.8%). This study found that 38.4% and 61.6% of the participants were SLT ever users and never users respectively. Among the ever users, 29.5% were current users and most tried (47.7%) at the age of 10–14 years. Most participants revealed that homes and public places were common sites for SLT use. Paan Masala and Gutkha were the most commonly preferrable SLTs. This study found that age (AOR = 1.5, CI: 1.2–2.2), sex (AOR = 2.6, CI:1.6–4.4), and school type (AOR = 1.8, CI:1.1–3.0) were significantly associated with the prevalence of SLT.ConclusionThis study found that the prevalence of current SLT users is higher than the national survey. This study concludes that males, young adolescents, and students from private schools are at greater risk of SLT use and are unaware of the consequences on their health. Concerned stakeholders must expand awareness and promote educational programs on the harmful use of tobacco targeting secondary school students. The government organizations, educational institutions, and private organizations jointly work to strengthen the implementation of tobacco cessation programs and tobacco control strategies.
Hubungan Aerosol Optical Depth (AOD) dengan Materi Partikulat 10 Mikron (PM10): Studi Literatur
Authors: Dirgawati Mila , Larasati Nabila Ayu 
Published: November 2024

Studi ini mengkaji berbagai penelitian mengenai hubungan aerosol optical depth (AOD) yang diperoleh dari pengukuran data satelit dengan materi partikulat 10 mikron (PM10) hasil pengukuran ground-based di negara dua dan empat musim. Referensi yang digunakan adalah jurnal yang telah dipublikasikan tahun 2013-2022 yang dengan menggunakan Mendeley dan Google Scholar. Hubungan AOD dan PM10 ditinjau dari nilai koefisien korelasi (r) dan koefisien determinasi (R2). Berdasarkan nilai r, ditemukan bahwa hubungan antara AOD dan PM10 di negara dua musim sangat kuat dengan nilai r ≥ 0,80, sedangkan di negara empat musim nilai hubungannya sangat bervariasi, yaitu r = 0,1-0,9 tergantung musim. Hubungan AOD-PM10 di negara dua musim dipengaruhi oleh penggunaan lahan, kegiatan manusia, dan kondisi meteorologi (kelembapan relatif dan temperatur permukaan). Hubungan AOD-PM10 di negara empat musim dapat dipengaruhi oleh kondisi topografi, kegiatan manusia (industri), dan faktor meteorologi dengan kelembapan relatif merupakan faktor yang paling berpengaruh terhadap hubungan AOD dan PM10. Berdasarkan nilai R2 yang dihasilkan, ditemukan bahwa nilai AOD dari data satelit mampu merepresentasikan konsentrasi PM10 lebih dari 70% di negara dua musim dan lebih dari 83% di negara empat musim sehingga nilai AOD dapat digunakan untuk estimasi konsentrasi PM10.
Analysis the Effect of Flux and Water Characteristics on Polyethersulfone Ultrafiltration Membrane Performance as Pre-Treatment of SWRO
Authors: Laksono Sucipta , Irwan Irwan , Adityosulindro Sandyanto 
Published: November 2024

Increasing human population resulted in higher demand for potable freshwater, while freshwater sources were limited. As an alternative solution, seawater was necessarily to be employed as a main source of water supply and necessarily treated with Seawater Reverse Osmosis (SWRO). However, membrane fouling of SWRO was occurred. Therefore, implementation of ultrafiltration membranes as pre-treatment were necessary. In this study, identification of removal efficiency seawater characteristics of TDS, COD, conductivity, and UV-Vis parameters at different flux and investigation of the fouling rate at variations filtration performance of the 50 kDa MWCO pore size PES ultrafiltration membrane was performed. Filtration of laboratory scale experiment with constant flux of 120 L/m²⋅h and 180 L/m²⋅h at dead-end operation was performed. Filtration of 50 kDa PES ultrafiltration membrane was able to remove effectively turbidity, TDS, UV-Vis, conductivity, and COD with 63±6%; 37±19%; 7±4%; 33±33%; dan 97.86%, respectively. Furthermore, related to membrane performance, filtration at 120 L/m²·h flux operation was found as the common fouling mechanisms, while flux operation at 180 L/m²·h resulted different behavior resulted for severe membrane performance. The suitable operation of fluxes 120 L/m²·h was recommended to increase the performance and membrane lifespan as well as to decrease the load of SWRO unit.
Perancangan Organic Coastal Defence (OCD) sebagai Penangkap Lumpur untuk Mendukung Pertumbuhan Tanaman Mangrove di Mempawah Mangrove Park
Authors: Permanus Trimei , Utomo Kiki Prio , Jumiati Jumiati 
Published: November 2024

Ekosistem Mangrove di Mempawah Mangrove Park (MMP) Kabupaten Mempawah, Provinsi Kalimantan Barat telah mengalami abrasi, sehingga pada tahun 2011 MMP melakukan penanaman mangrove. Penanaman terkadang mengalami kegagalan setelah 1 hingga 2 bulan penanaman, mangrove yang ditanam tumbang dan mati oleh arus pesisir pantai. Tahun 2022 pihak MMP berkolaborasi dengan mahasiswa Teknik Lingkungan UNTAN yang dinaungi oleh UPT Laboratorium Terpadu UNTAN pada kegiatan Matching Fund. Kolaborasi tersebut membuat bangunan penahan lumpur (mud trap) dan pemecah gelombang (breakwater). Kedua bangunan tersebut dinamai Organic Coastal Defence (OCD). Pembangunan OCD yang dibuat pada tahun 2022 belum mempunyai dasar ilmiah secara tertulis untuk dapat direplika di lokasi lain. Berdasarkan latar belakang tersebut maka perancangan OCD dengan dasar ilmiah akan dilakukan dengan observasi lapangan dan melakukan perhitungan prediksi gelombang laut berdasarkan data angin dari Badan Meteorologi Klimatologi Geofisika (BMKG) Maritim Pontianak. Hasil prediksi gelombang laut dengan tinggi 1,6 meter dengan periode 7 detik. Hasil dari analisis bangunan breakwater mempunyai panjang 99 meter, jarak antar breakwater 55 meter, tinggi tiang 1,8 meter, kedalaman tiang 1,5 meter dan jarak antar tiang 0,23 meter serta bangunan mud trap mempunyai panjang 99 meter, lebar 9 meter, tinggi 0,1 meter, kedalaman papan 0,9 meter. Posisi bangunan OCD menghadap ke arah laut.