bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the patterns of thrombocytopenia in pregnancy: unravelling implications and outcomes
Authors: Mathesan Manju , Ethirajan Shanthi 
Published: November 2024

: Thrombocytopenia, characterized by reduced platelet count, is a hematological disorder that can manifest during pregnancy. The intricate physiological changes of pregnancy and underlying medical conditions contribute to the complexity of thrombocytopenia, impacting both maternal health and fetal outcomes.: A prospective observational study conducted from March 2022 to November 2023 at Saveetha Medical College. Participants included pregnant women aged 18-40 got admitted and regular blood tests assessed platelet counts, with additional data collected on demographics, medical history, and lifestyle. Maternal outcomes and fetal/neonatal outcomes were monitored. Statistical analysis employed descriptive statistics and regression analysis. Out of 1980 deliveries, 88 patients (4.4%) had thrombocytopenia. Causes included gestational thrombocytopenia (42%), dengue (32%), severe pre-eclampsia (11%), eclampsia (6%), immune thrombocytopenia (4%), scrub typhus (2%), HELLP syndrome (2%), and partial HELLP syndrome (1%). Temporal distribution revealed 77% of diagnoses in the third trimester, emphasizing late pregnancy onset. Thrombocytopenia severity showed 69% mild, 30% moderate, and 1% severe cases. Primiparous women were more likely to present with severe thrombocytopenia (p=0.03). Perinatal outcomes depend upon the causes of thrombocytopenia in mother which includes fetal growth retardation (9%), neonatal thrombocytopenia (4%), birth asphyxia (3%), and intrauterine death (2%).: This study contributes comprehensive insights into thrombocytopenia during pregnancy, identifying diverse causes and highlighting the importance of monitoring. The findings inform clinical practice, enhance prenatal care, and emphasize the need for early detection and individualized interventions.
What are the primary stressors faced by Obstetrics and Gynaecology residents? Do their coping strategies align with adaptability or maladaptability, as per the Brief COPE assessment?
Authors: Madan Shikha , Dahiya Pushpa , Singhal Savita Rani , Chauhan Meenakshi , Duhan Nirmala 
Published: November 2024

: Obstetrics and Gynaecology is a demanding and challenging speciality of medical education. The residents are the first level of contact of all patients. The aim and objectives of the study were to find what causes stress in the residents of Obstetrics and Gynaecology and their coping techniques. We conducted a cross-sectional study on 45 residents pursuing post-graduation in Obstetrics and Gynaecology at PGIMS, Rohtak. : The cause of stress in residents was long working hours, having less time for friends and family, too much paper work, new subject learnings, expectations to perform well in clinics. The coping techniques were identified like listening to music, watching movies, talking to friends and family. According to the Brief COPE assessment, the coping techniques used were adaptive in residents of Obstetrics and Gynaecology of our institute. Those working in demanding fields like Obstetrics and Gynaecology face unique challenges and have their own coping techniques. The well-being of medical residents directly impacts their future performance as physicians
Transcerebellar diameter / abdominal circumference (TCD/AC) versus (HC/AC) head circumference / abdominal circumference --- USG prediction of fetal growth restriction? What do we observe in north Kerala, India
Authors: Shenoy Heera Trivikrama , Premarajan Ambika , Narayanan Saikrishna , Nair Lakshmi 
Published: November 2024

: Fetal growth restriction (FGR) refers to a condition in which a fetus is unable to achieve its genetically determined potential. A ratio of TCD /AC which is gestational age independent is very useful in predicting FGR. This prospective comparative study compared trans-cerebellar diameter / abdominal circumference versus head circumference / abdominal circumference in predicting fetal growth restriction. : A cross- sectional study done in 200 pregnant women attending Malabar Institute of Medical Sciences hospital during March 2018- May 2019. 40 pregnant women in third trimester with clinically suspected FGR over one year were the cases and 160 with normal growth pattern were the controls. Evaluation was done with 3.5 MHz frequency ultrasound. Fetal parameters such as BPD, HC, AC and FL were measured. Data were collected in Excel. Two morphometric ratios- TCD/AC and HC/AC will be calculated. Both TCD/ AC ratio and HC/AC of study group were compared with that of control group. The values above 2 standard deviations (SD) above mean were taken as FGR and was confirmed by postnatal newborn assessment by modified Ballard score. New born weight was compared with Fenton’s chart. If it was less than 10 percentile for the gestational age, it was diagnosed as a real case of FGR. Maximum number of cases (46.5%) belonged to the group 26-30 years. Around 23.5% in the group 31-35 years, 23% &#60;= 25 years and 7% of the cases were &#62;35 years. Clinical examination accounts for a sensitivity of 89.74%, Specificity of 96.9%, positive predictive value of 87.5% and negative predictive value of 97.5%. The sensitivity for TCD/ AC ratio is 94.87%. Specificity is 99.37%, positive predictive value is 97.36% and negative predictive value is 98.76%. TCD/AC and HC/AC were gestational age independent parameters and can be used in detecting IUGR with good diagnostic accuracy. However, TCD/AC ratio had a better diagnostic validity and accuracy compared to HC/AC ratio in predicting asymmetric FGR
Lactate dehydrogenase as a biochemical marker for prediction of maternal and perinatal outcomes in hypertensive disorders in pregnancy
Authors: Kumari Neha , Bala Ripan , Pahwa Sangeeta 
Published: November 2024

Hypertensive disorder of pregnancy includes new onset hypertension in pregnancy that is gestational hypertension and already existing hypertension that is chronic hypertension and gestational hypertension sometimes worsened by preeclampsia. Preeclampsia can cause complications such as eclampsia, HELLP syndrome, renal failure, pulmonary edema, stroke, and left ventricular failure. We aim to assessthe predictive role ofLactate Dehydrogenase value in Hypertensive disorders in pregnancy.After obtaining the informed consent, pregnant patients who were visiting Tertiary care centre and who were more than 28 weeks period of gestation were enrolled. Patients from both antenatal OPD clinics and from those who were presenting in emergency were included in this study. Serum levels of LDH were tested. Patients were monitored till delivery and 6 weeks following childbirth.The Mean serum levels of lactate dehydrogenase (LDH) in eclamptic group was 1495.000±859.1230, 804.569±224.5519 in severely preeclamptic group and in mild preeclamptic group ,mean LDH levels were 520.062±110.3944. The difference between both the groups was statistically significant (p &#60; 0.001).Women with serum LDH levels &#62; 800 IU/L and LDH levels between 601-800 IU/L, experienced considerably greater complications in preeclamptic-eclamptic group as compared to those with serum LDH levels &#60; 600 IU/L.Thepreeclamptic-eclamptic group of women had increased serum LDH levels. Greater LDH levels were linked to worse outcomes for mothers including placental abruption, hemolysis elevated liver enzymes low platelet count (HELLP syndrome), pulmonary edema and maternal death and they were also linked to fetal complications including intrauterine fetal death (IUFD), intrauterine growth restriction and neonatal intensive care unit (NICU) admission.
Histopathological evaluation of the placenta: Clues of intra-uterine fetal demise
Authors: Ahuja Arvind , Jha Tanvi , Sharma Monika 
Published: November 2024

Intrauterine fetal demise (IUFD) is a distressful event with lasting impact and risk of recurrence. However, in majority of cases, the cause remains unexplained. The aim of the present study is to evaluate the histomorphological features of placenta, the findings associated with commonly known etiologies of IUFD and other clues provided by it in establishing the cause of IUFD.: A prospective, observational study was conducted at a tertiary healthcare center in North India for a period of 3.5 years. A total of 104 placental specimen from IUFD cases were received and evaluated microscopically by 3 histopathologists. Data was tabulated and analyzed.: Majority cases of IUFD were seen in multigravida women (52.8%) in the age group of 25 to 30 years. We found that inflammatory lesions in 46.1% cases, maternal vascular malformation (MVM) in 25% cases, fetal vascular malformation in (FVM) in 16.3%, combined MVM and FVM in 2.9% while 9.7% cases were idiopathic. Presence of fibrotic villi, intervillous fibrin deposition, chorioamnionitis and calcification were the most common findings. Pregnancy induced hypertension was the most common maternal cause of IUFD identified (20.3%), while congenital anomalies were the most common fetal (72.1%) and placenta previa was the most common placental cause (33.3%). A comprehensive placental histopathological evaluation can provide clues regarding the causation and progression of IUFD, allowing clinicians to initiate early management and prevent recurrence. Patient education regarding the same may also motivate the patient to seek early and proper antenatal care in subsequent pregnancies.
Evaluating the effects of back massage during labour on delivery outcomes: A prospective study on primigravida mothers
Authors: Mishra Akash , Moncy Anitha , Jain Madhu , Kumar Ashok , Jain Shuchi , Kansal Sangeeta 
Published: November 2024

The labor and delivery process can be stressful for parturient women, especially for primigravida mothers. Birth companions providing massage and emotional support can help make more pleasant birthing experience. This study aimed to assess the impact of back massage by trained birth companions on reducing analgesic use, pain intensity scores, and labor duration. The study was conducted on primigravida women. During antenatal care visits, companions in the intervention group were trained in massage techniques, while no training was imparted to companions in the control group. Data were collected using a pre-tested questionnaire during antenatal clinic visits and delivery A multivariable logistic regression model was used to assess the impact of massage on delivery outcomes while adjusting for significant confounding variables.The study demonstrated a positive impact of back massaging on labor and delivery outcomes. Mothers in the massaged group were 2.27 times less likely to receive analgesics and 3.71 times more likely to experience a reduction in pain intensity scores of &#62; 2 compared to those receiving usual care. Additionally, the massaged group had a 2.24 times higher likelihood of reducing labor duration to &#60; 12 hours compared to the usual care group. Back massaging by trained birth companions is an effective intervention for reducing the use of analgesics, pain intensity scores, and the length of labor in primigravida women.
Побудова програмного забезпечення інформаційної системи формування спеціалізованих тематичних віртуальних спільнот
Authors: Паздерська Р.С. , Квасніков В.П. 
Published: November 2024

Стаття присвячена дослідженню процесів роботи програмного забезпечення спеціалізованих тематичних віртуальних спільнот на основі інформаційних повідомлень та поведінки користувача в соціальній мережі. Також увага приділяється дослідженням віртуальних спільнот, які зумовили виникнення спеціалізованих тематичних віртуальних спільнот.
Представлено результати роботи інформаційної системи формування спеціалізованих тематичних віртуальних спільнот, яка дозволить покращити процес поширення інформаційного наповнення користувачами. Увага зосереджена на таких процесах: створення спеціалізованої тематичної віртуальної спільноти на основі підбору користувачів, аналіз діяльності існуючої спеціалізованої віртуальної спільноти та її пошук з метою публікації визначеного інформаційного наповнення.
Представлено формальне моделювання для предметної області на основі якого відбувалося формулювання методології міри відповідності інформаційного наповнення спеціалізації та тематиці за визначеними ключовими словами та тегами, які використовувалися для реалізації завдань системи.
Результати дослідження можуть бути використані для оптимізації роботи спеціалізованих тематичних віртуальних спільнот.
INVESTIGATION OF VERTICAL AND HORIZONTAL DEFORMATIONS OF THE PNEUMATIC SPRING OF A HIGH-SPEED MOVING VEHICLE IN THE LIMITS OF THE ARROW OF THE ARROW GEAR
Authors: Kuzyshyn A. , Kovalchuk V. 
Published: November 2024

The object of the research is the pneumatic spring of the second stage of the spring suspension of the high-speed rolling stock of the railway. The vertical and horizontal deformations of the pneumatic spring within the scope of the arrow translation are studied. For constructive reasons, two sections of the turnout were chosen, namely the section of the tip of the spikes and the section of the root of the spikes. In order to determine the deformations of the pneumatic spring, a methodology for its full-scale testing has been developed, which includes the use of a test rig that has a rigid metal frame on which the pneumatic spring and measuring equipment are installed. High-frequency potentiometric linear displacement sensors were used to measure vertical and horizontal deformations. In accordance with the developed complex program of field tests, records of vertical and horizontal deformations of the pneumatic spring of the high-speed rolling stock were obtained during the movement of the turn signal in the forward and opposite directions. It was found that the vertical deformations of the pneumatic spring within the range of movement by the arrow transfer in the furrow and anti-furrow directions are greater than the horizontal ones. In addition, in the opposite direction of movement of the test rig, the vertical deformations of the pneumatic spring are larger compared to the opposite direction of movement. It was established that the maximum values of the vertical deformations of the pneumatic spring are within the range of 3.14–5.05 mm in the wool direction and 4.88–5.95 mm in the anti-wool direction. The maximum values of horizontal deformations are within 1.62–2.94 mm and 1.30–2.53 mm, respectively. It was established that the average value of the vertical and horizontal deformations of the pneumatic spring of the high-speed rolling stock within the range of the arrow of the turnout is: for forward motion – 3.85 mm and 2.02 mm, for forward motion – 5,48 mm and 1.82 mm, respectively. The obtained results will make it possible to proceed to the determination of the dynamic characteristics of the pneumatic spring, and at the stage of designing high-speed rolling stock to study its dynamic indicators and traffic safety indicators under different operating conditions.
THE STUDY OF THE TECHNICAL CONDITION OF GONDOLA CARS
Authors: Martynov Igor , Trufanova Alyona , Shovkun Vadim , Lytovchenko Oleksandr , Dmytrenko Maksym , Balashov Oleksandr 
Published: November 2024

The article presents the results of the analysis of the technical condition of gondola cars owned by the transport operator BGS rail. The composition of the model range of the car fleet was analysed. It is shown that 14 % of gondola cars produced by Uralvagonzavod have an average service life of over thirty years and have exhausted their service life. Gondola cars of models 12-757 and 12-753 of Kryukov Carriage Works have also exhausted their service life. A positive factor is the presence of innovative cars model 12-7023 produced by KVSZ and 12-4106 model produced by PJSC Dneprovagonmash in the car fleet. Their average age is 6.5 years.An analysis of the main causes of failures that caused the car to uncouple from the train along the route was carried out. In the first place are damage to body elements. This is followed by failures of automatic brakes and wheel sets.Among the damage to gondola car bodies, the first place is taken by malfunctions of the locks on the unloading hatch covers, followed by cracks and breaks in the upper and vertical sheets of the frame cross beams. Broken weld seams of braces and broken linings also pose a serious danger.Failures of auto brakes are caused by loosening of air duct pipes, brake equipment and welded shoes. The main causes of damage to wheel pairs are unacceptable wear of the flange. Among axle box assemblies, the vast majority of failures are caused by excessive heating of the bearings.Failures of automatic coupling equipment are most often caused by fractures of the centering beam and breaks (cracks) of the pendulum suspension. Cracks and other malfunctions of the automatic coupling body are also observed.The bogies mostly have broken springs and mismatched sliding clearances. Also, a quarter of the uncoupled bogies have expired service life of their elements.
The average recovery time for gondola cars was analyzed. Due to malfunctions of axlebox units, cars are under repair for more than 15 days, due to failures of wheel pairs - 11.55 days. The least time is spent on auto brakes – 4.2 days.An analysis of the damage to the bodies of various gondola cars models showed that gondola cars of models 12-9745 and 12-9790 are in the worst technical condition. The least susceptible to damage are the «innovative» gondola cars of models 12-7023 and 12-4106.
Production, Diversity, and Distribution of Aquaculture Commodities in Tuban, Indonesia
Authors: Samara Syifania Hanifah , Amin Muhamad , Isroni Wahyu , Hasan Veryl , Santanumurti Muhammad Browijoyo , Nugraha Muhammad Ar Rozzaaq , Abualreesh Muyassar H. 
Published: November 2024

Graphical Abstract

Highlight Research

Tuban (Indonesia) aquaculture commodities are surveyed.
Aquaculture diversity in Tuban are consisted of 5 fields, namely rice field ponds, floating net cages, freshwater ponds, and brackish aquaculture ponds
Aquaculture commodities in Tuban consist of 11 families and 14 species of the main aquatic production.
Cyprinus carpio or common carp is one of the commodities cultivated in four different aquacultures.

Abstract
Fishery is a sector expected to overcome the food crisis. Indonesia is one of the leading countries in high volumes of fishery production in most of its areas, including the Regency of Tuban in East Java Province. The area of Tuban Regency is 1,839.94 km2 with the coastline covers 65 km and a sea area of 22,608 km2. This study aims to provide information regarding aquaculture production, diversity, and distribution in Tuban. This study used a survey method in collecting fishery commodity data directly from aquaculture areas. The results of this study showed that the highest production came from the brackish water with a value of 32.46% (13,561.79 tons), followed by rice field pond (27.79% or 11,612.45 tons), freshwater pond (25.76% or 10,764.62 tons), floating net cage (13.97% or 5,836.59 tons), and marine (0.1% or 5.67 tons). Aquaculture biodiversity in Tuban consisted of 11 families and 14 species of the main aquatic produces, such as Cyprinidae (Cyprinus carpio, Barbonymus gonionotus, Parastromateus niger), Clariidae (Clarias bathracus), Pangasiidae (Pangasianodon hypophthalmus), Penaeidae (Penaeus monodon, Litopenaeus vannamei), Channidae (Channa striata), Cichlidae (Oreochromis niloticus, Oreochromis mosammbicus), Osphronemidae (Osphronemus gourami), Serranidae (Epinephelus), Lutjanidae (Lutjanus), and Chanidae (Chanos chanos). Cyprinus carpio or common carp is fish cultivated in four different aquacultures, namely rice field pond, floating net cages, freshwater ponds, and brackish aquaculture ponds. Unfortunately, the diversity and production of marine aquaculture has not been improved even though Tuban has large marine areas.
Genetic Relationship Analysis of Genus Nomorhamphus from Lindu Lake, Central Sulawesi and Adaptive Responses to Exposure Different Light Wavelengths
Authors: Hafidah Riva , Soelistyowati Dinar Tri , Sudrajat Agus Oman , Alimuddin  
Published: November 2024

Graphical Abstract

Highlight Research

Genus Nomorhamphusfrom three river inlets of Lindu Lake, Central Sulawesi was identified as Nomorhamphus with CO1 gene.
Green wavelength can accelerate growth and maturation.
Wild fish Nomorhamphus can complete life cycles in an aquaculture environment.
Domestication level two is completed.

Abstract
Genus Nomorhamphus is an endemic fish that can be found in Sulawesi, Indonesia. This fish belongs to the halfbeak group and has diverse colors and morphology. It has economic value as an export commodity in the ornamental fish trade. Exploration of the genetic relationship of genus Nomorhamphus in Central Sulawesi is still limited. Nomorhamphus's fulfillment of export demand still comes from wild catches. This study aimed to identify the genetic relationship of genus Nomorhamphus in the inlet rivers of Lake Lindu, Central Sulawesi, and evaluate the adaptation response of genus Nomorhamphus to different wavelengths of light exposure. Caudal fin of six fish from the three inlet rivers of Lake Lindu were preserved in 95% ethanol for DNA extraction purposes. This research used a completely randomized design with three treatment, namely rearing under white (400 nm), green (525 nm), and red (625 nm) light for 60 days. Each treatment had three replications in the form of aquariums, with each aquarium being filled with four fish. A total of 42 fish were utilized in the study. CO1 sequence was amplified with universal primers of FISH-F2 and FISH-R2. The PCR amplification products were then sequenced and performed with phylogenetic tree analysis. The genetic diversity analysis suggests that the genus Nomorhamphus of all three rivers, Lindu Lake, Central Sulawesi is one species as Nomorhamphus sp.. Male and female growth length and gonad maturation were developed faster under green light exposure, while survival rate, blood glucose level, and color quality were not significantly different under different light. Exposure of wild fish to green light Nomorhamphus sp. can accelerate gonad maturation and growth to accelerate domestication.
Genetic Diversity and Population Structure of Amphidromous Goby (Stiphodon semoni) in Western Part of Southern Java Waters
Authors: Romdon Ahmad , Simanjuntak Charles P. H. , Sulistiono  , Syahailatua Augy 
Published: November 2024

Graphical Abstract

Research Highlight

The genetic diversity of Stiphodon semoni is high.
All populations have high haplotype diversity except for Cimaja.
No genetic structure is observed within the populations of semoni.
The population of semoni has undergone demographic expansion.
Cibareno River has the potential to be a protected area.

Abstract
Fishing activities negatively impact fish populations, potentially causing a decline in fish stocks. Nevertheless, ensuring diversity and connectivity among populations can mitigate these adverse effects. To evaluate the connectivity of river mouths in the western part of Southern Java waters, we sequenced forty Stiphodon semoni individuals from five populations using mitochondrial cytochrome oxidase subunit 1 as molecular markers. The study revealed that S. semoni populations showed high diversity (0.821), with the population in Cimaja displaying the lowest diversity (0.464). Furthermore, the result of the analysis of molecular variance was a Fst value of 0.0630 with a p-value of 0.22. These results along with the result of the haplotype network indicated no significant genetic differences among these populations. This implies that the river mouths in the western part of Southern Java waters are interconnected. The distribution of mismatches showed a single peak, indicating that the populations have undergone demographic expansion. This information could be valuable for the conservation and management of S. semoni in the western part of the Southern Java waters.