Improving outcomes for people who are homeless and have severe mental illness in Ethiopia, Ghana and Kenya: overview of the HOPE programme
Authors: Hanlon Charlotte , Smartt Caroline , Mutiso Victoria , Yaro Peter , Misganaw Eleni , Read Ursula , Mayston Rosie , Birhanu Ribka , Dako-Gyeke Phyllis , Ndetei David , Asher Laura , Repper Julie , Eaton Julian , Chua Kia-Chong , Fekadu Abebaw , Tsigebrhan Ruth , Fofo Cecilia Ashaley , Kariuki Kimberly , Rai Sauharda , Abayneh Sisay , Amissah Caroline Reindorf , Boadu Amma Mpomaa , Makau Priscilla , Tadesse Agitu , Timms Phil , Prince Martin , Thornicroft Graham , Kohrt Brandon , Alem Atalay 
Published: November 2024

AbstractAimHOPE (National Institute for Health and Care Research Global Health Research Group on Homelessness and Mental Health in Africa) aims to develop and evaluate interventions that address the unmet needs of people who are homeless and have severe mental illness (SMI) living in three African countries in ways that are rights-based, contextually grounded, scalable and sustainable.MethodsWe will work in the capital city (Addis Ababa) in Ethiopia, a regional city (Tamale) in Ghana, and the capital city (Nairobi) and a rural county (Makueni) in Kenya to understand different approaches to intervention needed across varied settings.Formative work will include synthesis of global evidence (systematic review, including grey literature, and a Delphi consensus exercise) on interventions and approaches to improving outcomes for people who are homeless and have SMI. We will map contexts; conduct a focused ethnographic study to understand lived experiences of homelessness and SMI; carry out a cross-sectional survey of people who are homeless (n=750 in Ghana and Ethiopia; n=350 in Kenya) to estimate prevalence of SMI and identify prioritised needs; and conduct in-depth interviews and focus group discussions with key stakeholders to understand experiences, challenges and opportunities for intervention. This global and local evidence will feed into Theory of Change workshops with stakeholders to establish agreement about valued primary outcomes, map pathways to impact and inform selection and implementation of interventions. Intervention packages to address prioritised needs will be co-produced, piloted in each country with people who are homeless and have SMI, and will be optimised for feasibility and acceptability using participatory action research. We will use rights-based approaches and focus on community-based care to ensure sustainability. Realist approaches will be employed to analyse how contextual variation affects mechanisms and outcomes to inform methods for a subsequent evaluation of larger scale implementation. Extensive capacity strengthening activities will focus on equipping early career researchers and peer researchers. People with lived experience of SMI and policymakers are an integral part of the research team. Community engagement is supported by working closely with multi-sectoral Community Advisory Groups.ConclusionsHOPE will develop evidence to support action to respond to the needs and preferences of people who are homeless and have SMI in diverse settings in Africa. We are creating a new partnership of researchers, policy makers, community members and people with lived experience of SMI and homelessness to lead this work in and for the Global South.