bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serum concentrations of TFF3, S100-A11 and AIF-1 in association with systemic inflammatory response, disease stage and nodal involvement in endometrial cancer
Authors: Pilka Radovan , Neubert David , Stejskal David , Krejčí Gabriela , Švesták Marek , Marek Radim , Adam Tomáš , Sobkova Katerina , Ondrová Dana , Hambálek Jozef , Maděrka Martin , Solichová Dagmar , Kujovská Krčmová Lenka , Javorska Lenka , Melichar Bohuslav 
Published: March 2018

Abstract
To compare preoperative intestinal trefoil factor 3 (TFF3), allograft inflammatory factor-1 (AIF-1) and calgizzarin (S100-A11) serum levels in patients with endometrial cancer, endometrial hyperplasia and in healthy female controls. Serum levels of TFF3, S100- A11 and AIP-1 were analyzed in 98 consecutive patients with histologically verified endometrial cancer, in 43 patients with endometrial hyperplasia diagnosed during hysteroscopy and 24 controls with benign disease. Results were correlated with urinary neopterin/creatinine ratio, serum kynurenine, tryptophan, retinol, alpha-tocopherol, vitamin D, citrulline, C-reactive protein, interleukin-6 and clinical characteristics. S100-A11, and AIF-1 levels were higher in endometrial hyperplasia patients than in controls, and also significantly higher in endometrial cancer than in patients with endometrial hyperplasia. Serum concentrations of TFF3 and S100-A11 were associated with tumor stage and lymph node status. TFF3 exhibited positive correlation with age, IL-6, vitamin D, kynurenine, urinary neopterin/creatinine ratio and kynurenine/tryptophan ratio. S100-A11, as well as AIF-1 correlated positively with Il-6 and TFF3. TFF3, S100-A11 and AIF-1 represent potential biomarkers in patients with endometrial cancer. TFF3 and S100-A11 increase with tumor stage and lymph node involvement, reflecting higher tumor mass that is also associated with increased concentration of biomarkers of immune dysfunction.
Upper limb therapy in children with cerebral palsy (CP) – The Pirate Group
Authors: Pawlak Marta , Wnuk Beata , Kowalicka Daniela , Rosłoniec Aleksandra 
Published: March 2018

Abstract
Introduction: Children with cerebral palsy (CP) in the form of spastic hemiplegia experience numerous difficulties concerning an affected upper limb such as reaching for objects, gripping or manipulating them. These limitations affect their everyday activity. Conducting an effective and simultaneously an interesting therapy aimed at meeting the child’s individual needs and improving upper limb function is a challenge for a physiotherapist. The aim of the study was to assess the effectiveness of upper limb therapy carried out within the project titled “The Pirate Group” based on Constraint-Induced Movement Therapy (CIMT) and Bimanual Training (BIT) conducted in a specially arranged environment. Material and methods: The research included 16 children with CP in the form of spastic hemiplegia. Mean age of the study participants was 4.23 years. The children underwent a two-week Constraint-Induced Movement Therapy (CIMT) combined with Bimanual Training (BIT). In order to evaluate the effects of the therapy, each child underwent the Assisting Hand Assessment (AHA) prior to the therapy and after its completion. Results: Statistical analysis revealed a significant difference (p<0.05) between the results of AHA prior to and after the therapy (t(14)=9.12, p<0.0001). An improvement in the affected upper limb function was noted in all the children participating in the research. Conclusions: The project titled “The Pirate Group”, based on CIMT and BIT is an effective therapeutic intervention which improves spontaneous activity of the affected upper limb in children with hemiplegia.
Erweiterte Abschreckung in Asien: aktuelle Lehren für Europa
Authors: Rühle Michael 
Published: March 2018

Zusammenfassung:
Die US-amerikanische Politik der erweiterten Abschreckung für ihre Verbündeten in Ostasien ist durch die nuklearen Ambitionen Nordkoreas sowie die zunehmend militärisch unterfütterte Außenpolitik Chinas erneut ins Zentrum der Betrachtung gerückt. Die aktuelle Diskussion in Asien zeigt – nach einer Phase des Herunterspielens der nuklearen Dimension in der Sicherheits- und Bündnispolitik – erneut die bedeutende Rolle der erweiterten Abschreckung als Instrument zur Rückversicherung für die Verbündeten und damit zugleich zur Verhinderung der Weiterverbreitung von Nuklearwaffen. Für Europa, dessen nukleare Kooperation mit den USA im Rahmen der NATO institutionalisiert ist, bietet diese Debatte zahlreiche Lehren.
Protective effect of dexpanthenol (vitamin B5) in a rat model of LPS-induced endotoxic shock
Authors: Demirci Buket , Yilmaz Mustafa , Bektas Uysal Hilal 
Published: March 2018

Abstract

Objectives
This study investigated the protective effect of dexpanthenol (DEX) in the septic shock model of rats with biochemical parameters.

Methods
12–15 weeks old male 32 Wistar rats has been used for this study. Sepsis was induced by a single intraperitoneal injection of lipopolysaccharide (LPS) (5 mg/kg) and treatment groups received single intraperitoneal injection of DEX (500 mg/kg) just 30-min before. The blood and tissue samples were obtained 16 h later of LPS intervention under the ketamine and xylasine (50 and 5 mg/kg, respectively) anesthesia.

Results
Giving alone DEX did not alter any physiologic levels of biochemical markers. Induction of sepsis resulted in a marked increase in ALT, AST, urea, creatinine, lactate, procalcitonin, TNF-α, IL-1β levels to show the tissue damage. In all serum parameters, liver’s GSH, CAT levels and kidney’s CAT, GSH, MDA and NO levels have ameliorated by DEX treatment in sepsis group.

Conclusion
Along with the standard therapy of sepsis, DEX can be used as a safe way of restoring (anti)oxidant status of kidney and liver tissues. It can be effective to control cytokine pathway, to decrease procalcitonin and regulate the metabolic process of sepsis, such as lactate.
Efficient pseudo five-component synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol) derivatives promoted by a novel ionic liquid catalyst
Authors: Abshirini Zahra , Zare Abdolkarim 
Published: March 2018

Abstract
In this research, initial production and characterization of a novel Brønsted-acidic ionic liquid, namely, N,N,N′,N′-tetramethylethylenediaminium-N,N′-disulfonic acid hydrogen sulfate ([TMEDSA][HSO4]2), has been described (characterization was achieved using Fourier-transform infrared spectroscopy, 1H nuclear magnetic resonance (NMR), 13C NMR, and mass and thermal gravimetric spectra). Thereafter, utilization of [TMEDSA][HSO4]2 as a highly effectual catalyst for the synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol) derivatives through the one-pot pseudo five-component reaction of phenylhydrazine (2 eq.) with ethyl acetoacetate (2 eq.) and arylaldehydes (1 eq.) in relatively mild conditions, has been reported.
2-Naphthol-pyrazole conjugates as substrates in the Mannich reaction
Authors: Roman Gheorghe 
Published: March 2018

Abstract
Several novel 2-naphthol-pyrazole conjugates have been synthesized through the O-alkylation of 1-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]naphthalen-2-ol with methyl iodide, benzyl chloride, methyl bromoacetate and N-benzyl-2-bromoacetamide. The aminomethylation of these 2-naphthol-pyrazole conjugates has been examined employing the classical conditions for the Mannich reaction, and also by using N,N-dimethylmethyleneiminium chloride as preformed aminomethylating reagent. In both situations, aminomethylation of these substrates occurred at C-4 of the pyrazole ring. The bifunctional substrate 1-[(3,5-dimethyl-1H-pyrazol-1-yl)methyl]naphthalen-2-ol has been chemoselectively aminomethylated in the pyrazole ring using the same preformed aminomethylating reagent.
Una lauda e uno scongiuro da un registro dell’Archivio di Stato di Udine
Authors: Zanello Gabriele 
Published: March 2018

AbstractGiovanni Antonio Battaglia was a notary and a secular priest of the diocese of Aquileia. He was active between the late fifteenth and the first four decades of the sixteenth century in Gemona, his place of birth, in the castle of Porcia and the city of Udine. A register he compiled (Udine, Archivio notarile antico, n. 2247), contains two documents which are worthy of attention. The first one is a funeral lauda in Italian vernacular which completes the rather short list of the religious laude repertoire of the Friulian region between the fifteenth and sixteenth centuries. The second document is the text Dolce Regina, dona la tua pace. This work can be placed within the framework of the brotherhoods of the Battuti, which Battaglia served as a priest and as a teacher. A rather composite Latin text also appears on the same page of the notarial register. It includes an invocation to the Magi, a quote from the Scriptures and an adapted liturgical oration. The presence of this exorcism, unusual if compared to the local context of traditional beliefs and therapeutic practices, requires wide-ranging comparisons. The figure of Battaglia himself also deserves further analysis especially in order to understand his cultural background as well as clarifying his relationship with the humanists whom he was corresponding with.
Les soviétismes en roumain et dans les langues romanes
Authors: Costăchescu Adriana 
Published: March 2018

AbstractThe article focusses on the fate of Sovietisms in modern Romanian, i.e. the situation of words or phrases borrowed from Russian in the period of Soviet control over Eastern Europe (1945–1989). The borrowings reflect relevant concepts of Soviet-Communist economics, culture, politics and propaganda. Romanian received the largest number of Sovietisms of all Romance languages, mainly because of its close political relationship with the URSS. The use of terms which implicated a critical attitude towards the Soviet-Communist dictatorship (samizdat ‘samizdat’, aparatcic ‘apparatchik’, gulag ‘goulag’, etc.) was forbidden both in the URSS and in socialist Romania, but they passed into Russian and Romanian through western radio broadcasts, mainly Radio Free Europe/Radio Liberty. Today, most of those Sovietisms are no longer in use in Romanian.
Synthesis and Performance Evaluation of Epoxy Resin–Modified Shape Memory Polyurethane Sealant
Authors: Shen Dongya , Shi Shuang , Xu Tao 
Published: March 2018

Abstract
To evaluate the effects of epoxy resin (EP) on different properties of shape memory polyurethane (SMPU) when used as a sealant with a tailored thermal transition temperature (Tt) for concrete pavement joints, the thermal and dynamic mechanical performances were discussed to determine the shape memory switching temperature of EP-modified SMPU, and then the compatibility between EP and SMPU, microscopic morphology, shape memory effect, and tensile property were also characterized. The results indicate that the tailored Tt of EP-modified SMPU can be used as the shape memory switching temperature to match its working temperature. EP and SMPU show considerable compatibility. EP inhibits the crystallization of soft phase content and increases the hard phase content. Both hydroxyl and epoxy groups participate in chemical reactions. The ring-opening reactions occur between fractional benzenes and SMPU. EP was successfully grafted onto the main chains of SMPU. Additionally, the peak load, tensile strength, and elongation at break of SMPU are first increased and then decreased when the EP content increase. An EP content of 10 % improves the tensile properties of SMPU, but excessive EP content leads to a decrease in the tensile strength and elongation at break. Finally, it is found that a small amount of EP has little influence on the shape memory properties of SMPU, but EP can improve the tensile properties of SMPU. EP-modified SMPU shows excellent shape memory effects. The prepared EP-modified SMPU with the specially tailored Tt can meet the requirements of practical engineering when used as a sealant for concrete pavement joints.
Analisis Makro Ekonomi Sebelum dan Sesudah Penerapan Redenominasi Mata Uang
Authors: Febrida Maria , Karolina Br. Sebayang Lesta 
Published: March 2018

Rencana redenominasi rupiah di Indonesia menjadikan pengalaman beberapa negara yang telah menerapkan redenominasi mata uang penting untuk ditinjau dari sisi makro ekonomi saat sebelum dan sesudah redenominasi sehingga menjadi dasar pertimbangan bagi Indonesia mengambil keputusan dalam rencana penerapan redenominasi rupiah. Tujuan penelitian ini untuk mengetahui ada tidaknya perbedaan kondisi inflasi, nilai tukar, ekspor, penanaman modal asing (PMA) dan pertumbuhan ekonomi 1 tahun sebelum dan 1 tahun sesudah menerapkan redenominasi pada 20 negara yang telah menerapkan redenominasi. Penelitian ini menggunakan metode penelitian kuantitatif dengan alat analisis uji beda dua rata-rata sampel berpasangan. Hasil analisis menunjukkan bahwa pada variabel nilai tukar terdapat perbedaan antara sebelum dan sesudah redenominasi yaitu nilai tukar semakin lemah setelah penerapan redenominasi, sedangkan pada variabel inflasi, ekspor, PMA, dan pertumbuhan ekonomi tidak terdapat perbedaan sebelum dan sesudah redenominasi.

Rupiah redenomination which planned by Indonesia make the experience of countries that have implemented the currency redenomination is important to be reviewed in terms of macroeconomic before and after the redenomination so that it becomes a basic consideration for Indonesia to take decisions in the plan of implementation rupiah redenomination. The purpose of this study is to determine whether there is difference in the conditions of inflation, exchange rate, exports, foreign direct investment (FDI) and economic growth in the current 1 year before and 1 year after implementing the redenomination in the 20 countries that have implemented the currency redenomination. This study used a quantitative method, with analysis dependent sample t-test which showed that there is a difference between before and after redenomination in exchange rate variable is getting weaker after the implementation of the redenomination, while there is no difference before and after the redenomination in inflation, exports, FDI, and economic growth.
Determinan Kualitas Pembangunan Manusia di Kabupaten/Kota Provinsi Jawa Tengah
Authors: Yudhi Pramono Agung , Soesilowati Etty 
Published: March 2018

Penelitian ini bertujuan untuk menganalisis seberapa besar pengaruh pengeluaran pemerintah daerah sektor pendidikan, pengeluaran pemerintah daerah sektor kesehatan, rasio ketergantungan penduduk dan pendapatan perkapita terhadap pembangunan manusia yang diukur dengan IPM. Populasi penelitian terdiri dari 35 Kabupaten/Kota di Provinsi Jawa Tengah, menggunakan data sekunder dari Badan Pusat Statistik Provinsi Jawa Tengah dan Biro Keuangan Sekretaris Daerah Provinsi Jawa Tengah dalam periode 2009 sampai 2013. Variabel penelitian ini indeks pembangunan manusia, pengeluran pemerintah daerah sektor pendidikan, pengeluaran pemerintah daerah sektor kesehatan, rasio ketergantungan penduduk, dan pendapatan perkapita. Dalam penelitian ini, digunakan metode penelitian kuantitatif dengan menggunakan analisis regresi data panel model efek tetap (FEM) dengan metode Generalized Least Square (GLS). Hasil penelitian ini dapat diketahui bahwa pengeluaran pemerintah daerah sektor pendidikan berpengaruh positif dan signifikan terhadap IPM, pengeluaran pemerintah daerah sektor kesehatan berpengaruh positif dan signifikan terhadap IPM, rasio ketergantungan penduduk berpengaruh negatif dan signifikan terhadap IPM, sementara pendapatan perkapita tidak berpengaruh secara signifikan terhadap IPM.
This research has purpose to analyze how much influence of the local government expenditure in educational sector, local government expenditure in health sector, dependency ratio, and per capita income of a human development measured by HDI. the population of this research consists of 35 regionals in Central Java and region bureau money secretary of Central Java province among 2009 and 2013 period. the variables used in this research are HDI, local government expenditure in educational sector, local government expenditure in health sector, dependency ratio, and per capita income. in this research, quantitative and regression analysis of Fixed Effect Model is used as well as Generalized Least Square method (GLS). The results of this research are the outcome of regional government in educational and health sector influence significance and positively to the HDI, dependency ratio significance and negatively influence to the HDI, while per capita income does not influence significance to the HDI.
Analisis Faktor – Faktor yang Mempengaruhi Remitansi di Kabupaten Cilacap
Authors: Wisnu Putra Anggriawan 
Published: March 2018

Tujuan penelitian ini adalah untuk mengetahui pengaruh pendapatan, kebutuhan keluarga di daerah asal dan pengeluaran konsumsi TKI terhadap remitansi baik secara simultan maupun parsial. Populasi dalam penelitian ini meliputi seluruh tenaga kerja yang pernah dan akan berangkat menjadi TKI di kabupaten Cilacap sebanyak 50 orang. Adapun sampel yang digunakan dalam penelitian ini adalah Purpossive Sampling dimana semua anggota populasi digunakan sebagai sampel. Variabel yang digunakan dalam penelitian ini adalah pendapatan (X1), kebutuhan keluarga (X2), konsumsi pribadi (X3) dan remitansi (Y). Metode pengumpulan data yang digunakan dalam penelitian ini melalui wawancara terstruktur dengan menggunakan kuesioner. Analisis data yang digunakan adalah analisis regresi linier berganda dengan SPSS rilis 17. Hasil penelitian menunjukkan pendapatan dan kebutuhan keluarga berpengaruh positif dan signifikan terhadap remitansi, sedangkan konsumsi pribadi berpengaruh negatif signifikan terhadap remitansi. Simpulan dari penelitian ini yaitu secara parsial pendapatan dan kebutuhan keluarga berpengaruh positif dan signifikan terhadap remitansi. Ketika pendapatan dan kebutuhan keluarga meningkat maka remitansi akan meningkat begitu pula sebaliknya. Sedangkan konsumsi pribadi memiliki pengaruh negatif signifikan terhadap remitansi, yang berarti ketika konsumsi pribadi mengalami kenaikan maka remitansi mengalami penurunan. Sedangkan secara simultan model regresi dapat digunakan untuk memprediksi remitansi. Variabel pendapatan berperan sebagai variabel paling dominan mempengaruhi remitansi.
The purpose of this study was to determine the effect of income, family needs in the area of origin and consumption expenditure of remittances migrant workers against either simultaneously or partially. The population in this study are the entire workforce ever and will go into migrant workers in Cilacap regency with the number of sample are 50 people. The sample used in this study is the purpossive sampling where all members of the population used as sample. Variables used in this research are Income (X1), the family needs (X2), private consumption (X3) and remittances (Y). Data collection methods used in this study through interviews using a structured questionnaire. The data analysis used is linear regression analysis with SPSS release 17. The results showed that Income and Family Needs had a positive and significant effect against to remittances , while private consumption had significantly negative influence Against to remittances. This study concludes that partially income and family needs had positive and significant impact on remittances. When income and family needs increases, remittances will increase and vice versa. While private consumption has a significant negative effect on remittances, which means when the personal consumption increases then remittances decreased. While simultaneously obtained the regression model can be used to predict remittances. Variable income serves as the most dominant variable affecting to remittances.
Analisis Potensi Pengembangan Pusat Pertumbuhan Ekonomi di Kabupaten Karanganyar 2009-2013
Authors: Arumpaka Priangga Arumpaka 
Published: March 2018

Penelitian ini bertujuan untuk menentukan kecamatan yang berpotensi sebagai pusat pertumbuhan ekonomi di Kabupaten Karanganyar. Data yang digunakan dalam penelitian ini adalah data sekunder yaitu berupa data times series dengan periode waktu tahun 2009-2013 yang bersumber dari BPS Provinsi Jawa Tengah, BPS Kabupaten Karanganyar dan jurnal serta literatur yang berkaitan dengan penelitian. Metode analisis yang digunakan yaitu Tipologi Klassen, Analisis Location Quotient (LQ), Model Rasio Pertumbuhan (MRP), Analisis Overlay, Analisis Skalogram. Hasil penelitian ini menunjukkan bahwa yang menjadi pusat pertumbuhan ekonomi di Kabupaten Karanganyar dan kawasan kerjasamanya adalah Kawasan Barat dengan pusat pertumbuhan ekonomi Kecamatan Gondangrejo, Kawasan Tengah dengan pusat pertumbuhan Kecamatan Karanganyar, Kawasan Timur dengan pusat pertumbuhan Kecamatan Matesih, dan Kawasan Selatan dengan pusat pertumbuhan Kecamatan Jumantono. Kesimpulan dari penelitian ini bahwa terdapat empat kecamatan pusat pertumbuhan yang saling berinteraksi dengan kecamatan di sekitarnya.

This study aims to determine the potential districts as centers of economic growth in Karanganyar. The data used in this research is secondary data in the form of data time series with the time period of 2009-2013 taken from BPS Central Java province, BPS Karanganyar as well as journals and any other literatures which are related to the research. The analytical methods being used are Typology Klassen, Location Quotient analysis (LQ), Growth Ratio Model (MRP), Overlay analysis, and Schallogram analysis. The results of this study indicate that the center of economic growth in Karanganyar and its regional cooperation are the Western Region with the center of economic growth is in the District Gondangrejo, Central Region with the growth center is in Karanganyar, Eastern Region with Subdistrict Matesih as its center of economic growth, and South Region with Subdistrict Jumantono as its center. The conclusion is four sub-district as the center of economy growth interacting each other with the surrounding sub-district.