bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional contagion in children with autism spectrum disorder varies with stimulus familiarity and task instructions
Authors: Helt Molly S. , Fein Deborah A. , Vargas Jacob E. 
Published: March 2019

AbstractAlthough deficits in cognitive empathy are well established in individuals with autism spectrum disorder (ASD), the literature on emotional empathy, or emotional contagion, in individuals with ASD is sparse and contradictory. The authors tested susceptibility to contagious yawning and laughter in children with ASD (n= 60) and typically developing (TD) children (n= 60), ages 5–17 years, under various conditions, to elucidate factors that may affect emotional contagion in these populations. Although TD children showed equal amounts of emotional contagion across conditions, children with ASD were highly influenced by the familiarity of the target stimulus, as well as task instructions that encourage eye gaze to target. More specifically, children with ASD exhibited less contagious yawning and laughter than their TD peers except when their attention was explicitly directed to the eyes or (and even more so) when their parents served as the stimulus targets. The authors explore the implications of these findings for theories about the mechanisms underlying empathic deficits in ASD as well as the clinical implications of having parents involved in treatment.
People will enter the downtown – the postwar ruralisation of the proletarian city of Łódź (1945–55)
Authors: Zysiak Agata 
Published: March 2019

AbstractThis article deals with the postwar confrontation of the rural and the urban in Poland. It sheds light on a time of mass migration to the cities and the postwar reconstruction in Central Europe, heading towards state-socialism, and focuses on official discourses concerning peasants as new social and political subjects and the intelligentsia’s response to rural newcomers. A testing ground for these processes was the Polish city of Łódź, the biggest textile industrial centre.These processes became the subject of both journalistic and academic inquiries framed by political efforts to reshape the ‘social imaginary’ (Taylor) through the state’s ‘socialist modernization’. Along with the scale of migration, there was another unprecedented aspect: peasants were becoming citizens, recognised political subjects, later even as privileged representatives of the People’s Republic. The postwar press and political speeches encouraged them to become a part of the modernisation project. Almost immediately, counter-narratives followed and lamented the newcomers’ ‘improper’ uses of the city. The term ‘ruralisation of the city’ was coined to describe the misuses of urban spaces, a moral decline and even the negative influence of peasants on the urban working class.
Impaired Interparental Relationships in Families of Children With	Attention-Deficit/Hyperactivity Disorder (ADHD)
Authors: Weyers Lena , Zemp Martina , Alpers Georg W. 
Published: March 2019

Abstract. Research on attention-deficit/hyperactivity disorder (ADHD) in children and adolescents has traditionally focused on the genetic and neurobiological aspects of the disorder, but the role of family relationships has been much less systematically examined. There is growing evidence that the quality of interparental relationships and a child’s ADHD symptoms are reciprocally related. Because the literature appears to be inconsistent, this meta-analysis aims to summarize previous research and assess whether there are robust differences in the quality of interparental relationships between parents of children with ADHD and parents of healthy children. This meta-analysis of 15 studies with 43 effect sizes revealed a small but significant difference ( d = .24), which indicates that parents of a child with ADHD report poorer relationship quality than parents of healthy children. This effect was moderated by the child’s age and did not depend on whether the child had a comorbid oppositional defiant disorder (ODD) or conduct disorder (CD). The causality of this relationship has yet to be determined.
Accurate Measurement of Small Features in X‐Ray CT Data Volumes, Demonstrated Using Gold Grains
Authors: Ketcham R. A. , Mote A. S. 
Published: March 2019

AbstractWe present a method for measuring small, discrete features near the resolution limit of X‐ray computed tomography (CT) data volumes with the aim of providing consistent answers across instruments and data resolutions. The appearances of small features are impacted by the partial volume effect and blurring due to the data point‐spread function, and we call our approach the partial‐volume and blurring (PVB) method. Features are segmented to encompass their total attenuation signal, which is then converted to a volume, in turn allowing a subset of voxels to be used to measure shape and orientation. We demonstrate the method on a set of gold grains, scanned with two instruments at a range of resolutions and with various surrounding media. We recover volume accurately over a factor of 27 range in grain volume and factor of 5 range in data resolution, successfully characterizing particles as small as 5.4 voxels in true volume. Shape metrics are affected variably by resolution effects and are more reliable when based on image‐based caliper measurements than perimeter length or surface area. Orientations are reproducible when maximum or minimum axis lengths are sufficiently different from the intermediate axis. Calibration requires end‐member CT numbers for the materials of interest, which we obtained empirically; we describe a first‐principles calculation and discuss its challenges. The PVB method is accurate, reproducible, resolution invariant, and objective, all important improvements over any method based on global thresholds.
Prediction of Northern Hemisphere Regional Surface Temperatures Using Stratospheric Ozone Information
Authors: Stone Kane A. , Solomon Susan , Kinnison Douglas E. , Baggett Cory F. , Barnes Elizabeth A. 
Published: March 2019

AbstractCorrelations between springtime stratospheric ozone extremes and subsequent surface temperatures have been previously reported for both models and observations at particular locations in the Northern Hemisphere. Here we quantify for the first time the potential use of ozone information for Northern Hemisphere seasonal forecasts, using observations and a nine‐member chemistry climate model ensemble. The ensemble composite correlations between March total column ozone (TCO) and April surface temperatures display a similar structure to observations, but with slightly lower correlation magnitudes. This is likely due to the larger number of cases smoothing out sampling error in the pattern, which is visible in the difference between correlations calculated from individual ensemble members. Using a linear regression model with March TCO as the predictor, predictions of the following April surface temperatures in regions that show large correlations are possible up to 4 years following the regression model end date in individual ensemble members, and up to 6 years in observations. We create an empirical forecast model to predict the sign of the observed as well as the modeled surface temperature anomalies using March TCO. Through a leave‐three‐years‐out cross‐validation method, we show that March TCO can forecast the sign of the April surface temperature anomalies well in parts of Eurasia that show the lowest model internal variability.
Uncertainty in Assessing Temperature Impact on U.S. Maize Yield Under Global Warming: The Role of Compounding Precipitation Effect
Authors: Leng Guoyong 
Published: March 2019

AbstractHigh temperature alone would lead to a well‐understood loss of crop yields, but the compounding effects by other global change factors are much less well understood and can either amplify or reduce temperature‐driven yield change. Analysis focusing on U.S. maize yield shows that the concurrent changes in precipitation have nonnegligible influence on temperature‐yield relations. For the country as a whole, ~27% of the observed strength of temperature‐yield relation relates to the compounding precipitation effects. Further analysis shows that precipitation exerted the compounding effects mainly through its direct influence on yields rather than indirectly from its feedback to temperature. Under 2 and 1.5°C global warming, maize yield for the country as a whole is projected to decrease by ‐13.53 to ‐14.37% and ‐9.02 to ‐9.29%, respectively, with the magnitude of change depending on the climate model. Around 30% of the benefit by constraining global warming to 1.5°C would be contributed by the compounding precipitation effects, pointing to the important role of precipitation in regulating the impacts of temperature rise on yields. The results can greatly improve our understanding and interpretation of the important but uncertain temperature‐yield relations.
Spatioseasonal Variations of Atmospheric Ammonia Concentrations Over the United States: Comprehensive Model‐Observation Comparison
Authors: Nair Arshad Arjunan , Yu Fangqun , Luo Gan 
Published: March 2019

AbstractAtmospheric ammonia plays an important role in a number of environmental issues, including new particle formation and aerosol indirect radiative forcing. Over the United States, atmospheric ammonia has seen an increasing trend due in most part to the declining SO2 and NOx emissions. We conduct the first comprehensive assessment of multiyear Goddard Earth Observing System (GEOS)‐Chem simulated ammonia concentration ([NH3]) over conterminous United States along with surface observations from all 90 National Atmospheric Deposition Program Ammonia Monitoring Network (AMoN) sites that have at least 2 years of continuous measurements. Model‐simulated [NH3] is along empirically expected lines with regard to temporal trends, seasonal variations, and spatial distribution. GEOS‐Chem‐simulated [NH3], compared to AMoN observed values, has weighted average correlation (τ) of 0.50 ± 0.15 and mean fractional bias (MFB) of −8.8 ± 56%. Most sites (63 out of 90) have −60% < MFB < +60%. The deviations from observed values vary spatially and seasonally, and there is significant wintertime underestimation (−44 ± 58%) across most of conterminous United States (except the Pacific states). The largest positive deviations occur in the Pacific states (101 ± 46%) and the largest negative deviations in the Southern Plain states (−73 ± 39%) and the Mountain states (−73 ± 84%), both in the winter months. Over the Great Plains region, GEOS‐Chem simulated [NH3] shows a much stronger dependence to emissions than AMoN observed [NH3], indicating scope for improved representation of emissions for the region. Over Southeast United States, there appears to be the strong effect of the changing emissions of SO2 and NOx in both modeled and observed [NH3].
Wave‐Driven Sediment Resuspension Within a Model Eelgrass Meadow
Authors: Zhang Yinghao , Nepf Heidi 
Published: March 2019

AbstractWave velocity and suspended sediment concentration were measured over a sand bed with and without a model eelgrass meadow. The model meadow was geometrically and dynamically similar to the marine eelgrass Zostera marina. Meadows were constructed with three stem densities: 280, 600, and 820 stems/m2. Ripples formed within the meadow only when the spacing between stem rows was larger than the wave excursion. When ripples formed, the ripple geometry was the same as that observed for bare bed. When ripples were present, the near‐bed turbulent kinetic energy (TKE) was dominated by the ripple‐generated turbulence, and both the near‐bed TKE and averaged suspended sediment concentration were similar across all meadow densities and bare bed at the same wave velocity. When ripples were absent, the near‐bed TKE was dominated by the stem‐generated turbulence, and the averaged suspended sediment concentration was reduced, compared to cases with ripples but at the same wave velocity. For conditions with and without a model meadow, the sediment diffusivity inferred from vertical profiles of suspended sediment concentration increased linearly with distance from the bed.
Sea Ice Meltwater and Circumpolar Deep Water Drive Contrasting Productivity in Three Antarctic Polynyas
Authors: Moreau S. , Lannuzel D. , Janssens J. , Arroyo M. C. , Corkill M. , Cougnon E. , Genovese C. , Legresy B. , Lenton A. , Puigcorbé V. , Ratnarajah L. , Rintoul S. , Roca‐Martí M. , Rosenberg M. , Shadwick E. H. , Silvano A. , Strutton P. G. , Tilbrook B. 
Published: March 2019

AbstractIn the Southern Ocean, polynyas exhibit enhanced rates of primary productivity and represent large seasonal sinks for atmospheric CO2. Three contrasting east Antarctic polynyas were visited in late December to early January 2017: the Dalton, Mertz, and Ninnis polynyas. In the Mertz and Ninnis polynyas, phytoplankton biomass (average of 322 and 354 mg chlorophyll a (Chl a)/m2, respectively) and net community production (5.3 and 4.6 mol C/m2, respectively) were approximately 3 times those measured in the Dalton polynya (average of 122 mg Chl a/m2 and 1.8 mol C/m2). Phytoplankton communities also differed between the polynyas. Diatoms were thriving in the Mertz and Ninnis polynyas but not in the Dalton polynya, where Phaeocystis antarctica dominated. These strong regional differences were explored using physiological, biological, and physical parameters. The most likely drivers of the observed higher productivity in the Mertz and Ninnis were the relatively shallow inflow of iron‐rich modified Circumpolar Deep Water onto the shelf as well as a very large sea ice meltwater contribution. The productivity contrast between the three polynyas could not be explained by (1) the input of glacial meltwater, (2) the presence of Ice Shelf Water, or (3) stratification of the mixed layer. Our results show that physical drivers regulate the productivity of polynyas, suggesting that the response of biological productivity and carbon export to future change will vary among polynyas.
Understanding Ice Cloud‐Precipitation Properties of Three Modes of Mesoscale Convective Systems During PECAN
Authors: Cui Wenjun , Dong Xiquan , Xi Baike , Fan Jiwen , Tian Jingjing , Wang Jingyu , McHardy Theodore M. 
Published: March 2019

AbstractThis study analyzes the precipitation and ice cloud microphysical features of three common modes of linear mesoscale convective systems during the Plains Elevated Convection at Night (PECAN) campaign. Three cases, one for each linear mesoscale convective system archetype (trailing stratiform, leading stratiform, and parallel stratiform precipitation), are selected. We focus primarily on analyzing ice cloud microphysical properties and precipitation rates (PRs) over the classified convective core (CC) and stratiform rain (SR) regions, as well as the two stratiform regions that developed behind (SR1) and ahead (SR2) of the convective line relative to the storm motion. In the three selected cases, the ice water path (IWP) and PR have strong correlations in the CC, but not in the SR. In terms of the temporal evolution of the mean IWPs and PRs, both CC and SR IWPs, as well as CC PRs, reach peaks quickly but take a longer time to dissipate than the increase period. For all the three cases, both SR1 and SR2 IWPs are 20–70% of their corresponding CC values in both the leading stratiform and parallel stratiform cases and up to 95% for the trailing stratiform case, while all of their PRs are only 7–25% of their CC values. These values suggest not only that the SR PRs may depend on IWPs but also that the microphysical properties of ice particles such as habit and size distribution may play an important role. Utilizing cloud‐resolving simulations of these systems may provide better understanding of the physical meanings behind the results in the future.
Hydrogen sulfide: a gaseous signaling molecule modulates tissue homeostasis: implications in ophthalmic diseases
Authors: Han Yuyi , Shang Qianwen , Yao Jin , Ji Yong 
Published: March 2019

AbstractHydrogen sulfide (H2S) serves as a gasotransmitter in the regulation of organ development and maintenance of homeostasis in tissues. Its abnormal levels are associated with multiple human diseases, such as neurodegenerative disease, myocardial injury, and ophthalmic diseases. Excessive exposure to H2S could lead to cellular toxicity, orchestrate pathological process, and increase the risk of various diseases. Interestingly, under physiological status, H2S plays a critical role in maintaining cellular physiology and limiting damages to tissues. In mammalian species, the generation of H2S is catalyzed by cystathionine beta-synthase (CBS), cystathionine gamma-lyase (CSE), 3-mercapto-methylthio pyruvate aminotransferase (3MST) and cysteine aminotransferase (CAT). These enzymes are found inside the mammalian eyeballs at different locations. Their aberrant expression and the accumulation of substrates and intermediates can change the level of H2S by orders of magnitude, causing abnormal structures or functions in the eyes. Detailed investigations have demonstrated that H2S donors’ administration could regulate intraocular pressure, protect retinal cells, inhibit oxidative stress and alleviate inflammation by modulating the function of intra or extracellular proteins in ocular tissues. Thus, several slow-releasing H2S donors have been shown to be promising drugs for treating multiple diseases. In this review, we discuss the biological function of H2S metabolism and its application in ophthalmic diseases.
Stacking angle-tunable photoluminescence from interlayer exciton states in twisted bilayer graphene
Authors: Patel Hiral , Huang Lujie , Kim Cheol-Joo , Park Jiwoong , Graham Matt W. 
Published: March 2019

AbstractTwisted bilayer graphene (tBLG) is a metallic material with two degenerate van Hove singularity transitions that can rehybridize to form interlayer exciton states. Here we report photoluminescence (PL) emission from tBLG after resonant 2-photon excitation, which tunes with the interlayer stacking angle, θ. We spatially image individual tBLG domains at room-temperature and show a five-fold resonant PL-enhancement over the background hot-electron emission. Prior theory predicts that interlayer orbitals mix to create 2-photon-accessible strongly-bound (~0.7 eV) exciton and continuum-edge states, which we observe as two spectral peaks in both PL excitation and excited-state absorption spectra. This peak splitting provides independent estimates of the exciton binding energy which scales from 0.5–0.7 eV with θ = 7.5° to 16.5°. A predicted vanishing exciton-continuum coupling strength helps explain both the weak resonant PL and the slower 1 ps−1 exciton relaxation rate observed. This hybrid metal-exciton behavior electron thermalization and PL emission are tunable with stacking angle for potential enhancements in optoelectronic and fast-photosensing graphene-based applications.
Ventral tegmental area astrocytes orchestrate avoidance and approach behavior
Authors: Gomez J. A. , Perkins J. M. , Beaudoin G. M. , Cook N. B. , Quraishi S. A. , Szoeke E. A. , Thangamani K. , Tschumi C. W. , Wanat M. J. , Maroof A. M. , Beckstead M. J. , Rosenberg P. A. , Paladini C. A. 
Published: March 2019

AbstractThe ventral tegmental area (VTA) is a heterogeneous midbrain structure, containing neurons and astrocytes, that coordinates behaviors by integrating activity from numerous afferents. Within neuron-astrocyte networks, astrocytes control signals from distinct afferents in a circuit-specific manner, but whether this capacity scales up to drive motivated behavior has been undetermined. Using genetic and optical dissection strategies we report that VTA astrocytes tune glutamatergic signaling selectively on local inhibitory neurons to drive a functional circuit for learned avoidance. In this circuit, astrocytes facilitate excitation of VTA GABA neurons to increase inhibition of dopamine neurons, eliciting real-time and learned avoidance behavior that is sufficient to impede expression of preference for reward. Loss of one glutamate transporter (GLT-1) from VTA astrocytes selectively blocks these avoidance behaviors and spares preference for reward. Thus, VTA astrocytes selectively regulate excitation of local GABA neurons to drive a distinct avoidance circuit that opposes approach behavior.
Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase
Authors: Matsuzaki Kenichiro , Kondo Shizuka , Ishikawa Tatsuya , Shinohara Akira 
Published: March 2019

AbstractRAD51 assembly on single-stranded (ss)DNAs is a crucial step in the homology-dependent repair of DNA damage for genomic stability. The formation of the RAD51 filament is promoted by various RAD51-interacting proteins including RAD51 paralogues. However, the mechanisms underlying the differential control of RAD51-filament dynamics by these factors remain largely unknown. Here, we report a role for the human RAD51 paralogue, SWSAP1, as a novel regulator of RAD51 assembly. Swsap1-deficient cells show defects in DNA damage-induced RAD51 assembly during both mitosis and meiosis. Defective RAD51 assembly in SWSAP1-depleted cells is suppressed by the depletion of FIGNL1, which binds to RAD51 as well as SWSAP1. Purified FIGNL1 promotes the dissociation of RAD51 from ssDNAs. The dismantling activity of FIGNL1 does not require its ATPase but depends on RAD51-binding. Purified SWSAP1 inhibits the RAD51-dismantling activity of FIGNL1. Taken together, our data suggest that SWSAP1 protects RAD51 filaments by antagonizing the anti-recombinase, FIGNL1.
Enhancing oxygen evolution efficiency of multiferroic oxides by spintronic and ferroelectric polarization regulation
Authors: Li Xiaoning , Liu Huan , Chen Zezhi , Wu Qingmei , Yu Zheyin , Yang Mengmeng , Wang Xiaolin , Cheng Zhenxiang , Fu Zhengping , Lu Yalin 
Published: March 2019

AbstractRegulating the electronic structure of catalysts is the most efficient strategy yet, despite its limitations, to improve their oxygen evolution efficiency. Instead of only adjusting the electronic structure, here we utilize ferroelectric polarization to accelerate the oxygen evolution reaction as well. This is demonstrated on a multiferroic layered perovskite Bi5CoTi3O15 with in-situ grown BiCoO3. Thanks to the superimposed effects of electronic regulation and ferroelectric polarization, the as-prepared multiferroic electrocatalysts are more efficient than the benchmark IrO2 (with a final 320 mV overpotential at the current density of 10 mA cm−2 and a 34 mV dec−1 Tafel slope). This work not only demonstrates a low-cost and high-efficient OER electrocatalyst, but also provides a strategic design for multi-component electrocatalytic material systems by consideration of both spin and polarization degrees of freedom.
Rad52 prevents excessive replication fork reversal and protects from nascent strand degradation
Authors: Malacaria Eva , Pugliese Giusj Monia , Honda Masayoshi , Marabitti Veronica , Aiello Francesca Antonella , Spies Maria , Franchitto Annapaola , Pichierri Pietro 
Published: March 2019

AbstractStabilisation of stalled replication forks prevents excessive fork reversal and their pathological degradation, which can undermine genome integrity. Here we investigate a physiological role of RAD52 at stalled replication forks by using human cell models depleted of RAD52, a specific small-molecule inhibitor of the RAD52-ssDNA interaction, in vitro and single-molecule analyses. We demonstrate that RAD52 prevents excessive degradation of reversed replication forks by MRE11. Mechanistically, RAD52 binds to the stalled replication fork, promotes its occlusion and counteracts loading of SMARCAL1 in vitro and in vivo. Loss of the RAD52 function results in a slightly-defective replication restart, persistence of under-replicated regions and chromosome instability. Moreover, the RAD52-inhibited cells rely on RAD51 for completion of replication and viability upon replication arrest. Collectively, our data suggest an unexpected gatekeeper mechanism by which RAD52 limits excessive remodelling of stalled replication forks, thus indirectly assisting RAD51 and BRCA2 in protecting forks from unscheduled degradation and preventing genome instability.