bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single amino acid mutations in histone H3.3 illuminate the functional significance of H3K4 methylation in plants
Authors: Xue Mande , Ma Lijun , Li Xiaoyi , Zhang Huairen , Liu Qian , Jiang Danhua 
Published: December 2024

AbstractAlthough numerous data have revealed correlations between histone modifications and chromatin activities such as transcription, proofs of their causal importance in gene expression regulation remain limited. Sequence variants within each histone family expand chromatin diversity and may carry specific modifications, further raising the question of how histone modifications coordinate with different variants. Here, we investigate the regulatory role of lysine 4 (K4) ofArabidopsishistone H3 by point mutating K4 in two major H3 variants, H3.1 and H3.3. K4 is essential for the function of H3.3 but not H3.1 in plant development. H3K4 methylation levels decrease drastically upon K4 mutation in H3.3, and the associated transcriptome changes are similar to those observed in a mutant lacking SDG2, a major enzyme responsible for depositing H3K4 trimethylation (H3K4me3). Moreover, H3.3K4 and SDG2 are required for de novo gene activation and RNA Pol II elongation. H3K4 methylation is preferentially accumulated on H3.3 compared to H3.1, likely due to the close association of the H3.3 deposition and H3K4 methylation machineries. Furthermore, we reveal the diverse impacts of K4 nearby residue mutations on H3K4 methylation and H3.3 function. Collectively, these findings suggest that H3.3 serves as a critical substrate for H3K4 methylation, which is important for gene expression regulation. In addition, our work highlights the potential of using plants as a platform to directly investigate the importance of histone amino acids and their modifications.
A photorespiratory glyoxylate shunt in the cytosol supports photosynthesis and plant growth under high light conditions in Arabidopsis
Authors: Jiang Xiaotong , Koenig Amanda M. , Walker Berkley J. , Hu Jianping 
Published: December 2024

AbstractPhotorespiration, a central aspect of plant metabolism that is tightly connected to photosynthesis, functions in part to support photosynthetic performance, especially under stress conditions such as high light. However, our understanding of the mechanisms underlying the role and regulation of photorespiration in plant response to high light is limited. To identify modulators of photorespiration under high light, we isolated genetic suppressors of the photorespiratory mutanthpr1, which is defective in the peroxisomal hydroxypyruvate reductase 1. A suppressor that partially rescuedhpr1under high light was mapped toGLYR1, which encodes the cytosolic glyoxylate reductase 1 enzyme that converts glyoxylate to glycolate. IndependentGLYR1loss-of-function mutants also partially rescuedhpr1and another photorespiratory mutant,catalase 2. Our genetic, transcriptomic and metabolic profiling analyses together suggested a novel connection between cytosolic glyoxylate and a non-canonical photorespiratory route mediated by the cytosolic HPR2 enzyme, which we named the photorespiratory glyoxylate shunt. This shunt is especially critical under high light intensities when a high rate of photorespiratory flux is required and in the absence of a properly functional major photorespiratory pathway. Our findings support the metabolic flexibility of photorespiration and may help future efforts to improve crop performance under stress.
Do investors care about carbon emissions? Evidence based on stock return co-movement with machine learning-augmented data
Authors: Li Lucas S. , Zhao Yan 
Published: December 2024

PurposeThis paper represents the first attempt to examine investor behavior for green stocks through the lens of return co-movement, and provides evidence indicating that green investment practices have gained traction after 2012.Design/methodology/approachWe empirically test the hypotheses that the stock returns of firms with similar carbon dioxide emissions levels move together and, if so, whether this co-movement has increased over time as people become more “carbon-conscious.” Our baseline sample, based on carbon emissions data from public company disclosures, suffers from limited coverage, particularly before 2016, leading to low statistical power and sample selection bias. To address this, we employ machine learning methodologies to forecast the carbon emissions of firms that do not disclose such information, nearly quadrupling the sample size. Our findings indicate that stocks with similar carbon emissions exhibit higher co-movement in stock returns in both the baseline and augmented data samples. Furthermore, this co-movement has increased during the 2012–2020 period compared to the 2004–2011 period, suggesting that green investment has gained traction over time.FindingsWe find that stocks with similar carbon emissions exhibit higher co-movement in stock returns in both the baseline sample and the augmented data sample, and the co-movement has increased in the 2012–2020 period compared to the 2004–2011 years, suggesting that green investment has gained traction over time.Originality/value(1) We use machine learning methodology to augment carbon emissions sample which goes back to 2004. Our approach almost quadruples the original data, enabling large-sample testing. (2) We are the first paper to examine how green companies' stock returns co-move and thus provide complementary results on the research on expected returns and carbon emissions.
How do team faultlines damage team voice behavior? Comparing the effects of objective and perceived faultlines
Authors: Qiu Yong , Gao Yuting , Liu Jianting , Wang Wenzhou , Tian Yalin , Sun Xiaoran 
Published: December 2024

Purpose
The continuous upgrading of new technologies and rapid changes in their external environment have made organizations more dependent than ever on the ability of their employees to quickly identify problems and make timely course corrections. This dependency is not limited to individual employee voice but extends to the collective voice of the team. In the Chinese context, collective silence prevails. Following social identity theory, this study aims to explore the mechanisms and conditional processes underlying the relationship between team faultlines and team voice behavior and examine whether there are differences between the effects of objective and perceived faultlines.

Design/methodology/approach
The proposed model was tested through questionnaires with 377 team members from 71 teams, which were conducted through team leader–member pairing survey. The correlation and hierarchical stepwise regression analyses were used to test the hypotheses rigorously, and the questionnaire data was analyzed using SPSS 26.0, AMOS 25.0 and R 3.6.1.

Findings
The results show that both objective and perceived faultlines have a negative impact on team voice behavior and that the latter has a stronger negative effect. Team psychological safety mediates the relationship between team faultlines and team voice behavior. In addition, benevolent leadership, moral leadership and Zhongyong thinking positively moderate the negative effect of objective faultlines on team voice behavior; Zhongyong thinking also moderates the mediating effect of team psychological safety on the relationship between objective faultlines and team voice behavior.

Originality/value
The results of this study provide a deeper understanding of team faultlines and team voice behavior, and practical implications are provided for managers and future researchers to improve voice behavior in organizations.
Cultural intelligence and cooperation in the construction industry: the mediating role of trust
Authors: Paing Kyaw Kyaw , Dodanwala Tharindu C. , Santoso Djoen San 
Published: December 2024

Purpose
This study aims to investigate the mediating role of trust in the relationship between cultural intelligence (CQ) and cooperation among construction professionals. Furthermore, this study assesses perceived differences in CQ, trust and cooperation between individuals with and without experience working with foreigners in the construction industry.

Design/methodology/approach
Data were gathered from a cross-sectional survey of 408 engineers in Myanmar’s construction industry. A confirmatory factor analysis validated structural equation modeling approach was used to address research hypotheses, and an independent samples t-test was performed to identify the perceived differences between two categories of respondents.

Findings
The structural equation modeling results identified CQ as a positive direct predictor of cooperation, affect-based trust and cognition-based trust. Both affect-based trust and cognition-based trust directly and positively influenced cooperation. The relationship between CQ and cooperation was partially mediated by affect-based trust and cognition-based trust. The findings of the independent samples t-test revealed that construction employees with prior experience working with foreigners tend to exhibit a higher level of CQ, trust and cooperation than their counterparts.

Originality/value
The present study added the mediating role of trust in CQ and cooperation linkage, an area that has received limited attention in the literature.
The role of women in HRM in family SMEs
Authors: Flamini Giulia , Morelli Chiara , Gnan Luca , Cori Enrico 
Published: December 2024

PurposeThis study tries to free women from the “invisible role” prison and understand the different managerial goals and styles adopted by males and females in family small and medium enterprises (SMEs) in managing employees. In particular, this paper grasps the complexity of the relationship between women’s leadership positions and configurational human resource management (HRM) practices in family SMEs.Design/methodology/approachThe authors use the qualitative fuzzy set comparative analysis (fsQCA) on 623 small and medium Italian family businesses to explore women’s contributions and impacts on adopting HRM practices and business performance.FindingsThe findings confirm that gender-specific leadership styles influence the adoption of distinct bundles of HRM practices and ultimately affect organizational performance in family SMEs. Indeed, women in the family SME social context, to meet certain gender expectations, are more likely to implement steward-oriented HRM practices. This reinforces the role of women as key players in improving organizational performance by adopting people-centered HRM practices that promote employee satisfaction and retention.Originality/valueUsing the fsQCA analysis and the gender theory, family business and HRM literature, the paper investigates the role of women in Italian family SMEs as CEOs or HR managers in implementing HR management practices to achieve good organizational performance.
Exploitative leadership and green innovative behavior of hospitality employees: mediation of emotional exhaustion and moderation of perceived organization support
Authors: Sahibzada Yaseen Ahmad , Ali Muhammad , Toru Naveed , Farooq Jan Muhammad , Ellahi Abida 
Published: December 2024

PurposeThis study aimed to investigate the relationship between exploitative leadership (EL) and employee green innovative behavior (GIB) in the hospitality sector organizations of Pakistan. The relationship between EL and GIB is mediated by emotional exhaustion (EE). Perceived organizational support (POS) is used as a moderator between EL and EE.Design/methodology/approachThe study used convenience and purposive sampling techniques from the population, and the data collected on the structured questionnaire were analyzed through structural equation modeling (SEM) using SmartPLS. The data analysis involved the assessment of the measurement model and structural model.FindingsThe results of the data analysis show that EL has a significant and negative influence on employee GIB, and EE mediates the relationship, meaning EE caused by EL lowers GIB. The moderating effect of perceived organization support between EL and EE also lowers the effects of EL and diminishes EE leading to increased GIB.Practical implicationsThe findings of the study suggest that organizations in the hospitality sector like hotels and resorts need to focus on the POS to curb EE in employees due to EL to accelerate positive attitudes at work. Investments of resources in this avenue can enhance employee engagement and improve organizational performance while contributing to environmentally sustainable goals.Originality/valueThe originality of the study lies in the findings that in the presence of higher perceived organization support, the negative effects of EL are mitigated, and this leads to the replenishment of the emotional resources of employees, which allows them to engage in GIBs. GIB is a term that is being researched by the scholars in the hospitality industry of Pakistan. Conservation of natural resources is only possible through individual efforts, especially the efforts of individuals whose livelihoods depend on environmentally related industries, such as hospitality.
How intentions to use of OGD and respective portals changed over time: evidence from a three-year study among Czech students
Authors: Lnenicka Martin , Machova Renata 
Published: December 2024

PurposeBuilding an open data ecosystem is a long-term process during which it is necessary to collect feedback so that its development corresponds to the preferences and needs of users. The purpose of this paper is to provide findings and recommendations on how the intentions to use of Open Government Data (OGD) and OGD portals by Czech students evolved over the three years period from 2021 to 2023.Design/methodology/approachA mixed research approach was used to conduct the research study and to collect input data. A methodology followed the behavioural intention-based analysis using the model developed by Lnenicka et al. (2022) to analyse relationships between respective constructs and test the hypotheses. Each cycle of data collection using structured questionnaires was supplemented with semi-structured interviews to get students’ feedback on the findings.FindingsThe findings revealed that intentions to use of OGD and OGD portals by Czech students slightly decrease every year. Although students believe that using OGD is beneficial, can increase their performance and productivity, as well as they are influenced by other people to try to (re)use OGD, they miss concrete support above their daily activities in which they could use OGD. Therefore, we provided recommendations to improve their (re)use such as linking OGD with life events to show their usefulness for concrete life situations and activities.Originality/valueThe study provides insights into how intentions to use of OGD and OGD portals among Czech students evolved over the years and what should be the actions to consider improving the level of use. It provides governments on all administrative levels the recommendations for further improvements and actions to promote and stimulate the (re)use of OGD by students as well as other stakeholders.
An examination of the valuation process in a low transparent property market – perspectives of property valuers in Nigeria
Authors: Adilieme Chibuikem Michael , Abidoye Rotimi Boluwatife , Lee Chyi Lin 
Published: December 2024

PurposeThe finance sector and property market challenges in some global regions have been linked to inefficient property valuation practices. As a result, global valuation professional organisations have set up standards and norms to promote efficient and transparent operations in the property valuation industry. Despite these concerns, valuation industries in some countries still face challenges that threaten their smooth operations. One of such is Nigeria, which faces various problems attributable to its valuation process and regulatory system. Consequently, this paper aims to examine the valuation process in Nigeria with a bid to identify the weaknesses in its valuation process and how it contributes to problems identified in the literature.Design/methodology/approachA qualitative research approach was adopted, and semi-structured interviews were conducted with 12 valuers across different segments of the valuation industry in Nigeria. The data were subjected to thematic analysis using Nvivo 12 software.FindingsOur findings indicate a fundamentally weak valuation system and regulatory system marked by an opaque engagement process, underpricing of valuation services, inefficient domestication of international valuation standards, poor implementation and monitoring system and concerns about the training and certifications to meet global norms. These identified weaknesses contribute to and fuel problems such as client influence and valuation inaccuracy, among others.Practical implicationsThe study has some implications for the valuation professional organisations in Nigeria. The valuation professional organisations should devise systems and enact standards that go beyond solely replicating the IVS and RICS Red Book to effective domestication to suit local norms. Given the inefficient implementation and monitoring system, the use of proptech that supplements legal instruments needs to be adopted. Furthermore, the regulations should be strengthened in line with the trends of sustainability, duty of care and use of data as advocated by the IVSC. This will promote trust in the system and allow global stakeholders to transact more confidently with the Nigerian industry, as the current set-up does not evoke sufficient confidence in the system to deliver excellent and transparent valuation assignments.Originality/valueThis study provides perspective from an untransparent property market on the implications of a poor regulatory system and valuation process for valuers and stakeholders who may rely on valuations conducted in such an environment for decision-making. The findings from this study potentially provide input for the valuation professional organisation in Nigeria in identifying the gaps in their framework and current practices and providing some suggestions to promote improvements.
Epidemiological Survey of Canine Distemper Virus Infection: Exploring the Link Between Virus Spread and Invasive Raccoon (Procyon lotor) Population Growth in Hokkaido, Japan
Authors: Minamikawa Miku , Ito Mebuki , Kovba Anastasiia , Kobayashi Yumi , Abe Go , Kooriyama Takanori , Maeda Ken , Shimozuru Michito , Tsubota Toshio , Sashika Mariko 
Published: December 2024

ABSTRACTInvasive raccoons (Procyon lotor) naturalized in Hokkaido, Japan, potentially spreading infectious diseases. Canine distemper virus infection is a serious epizootic disease, for which the raccoon is one of the hosts. We investigated the virus's prevalence in Hokkaido's wild raccoons, using 611 serum samples collected from captured raccoons in 2007–2012, 2021, and 2022. Higher seropositivity rates were confirmed in 2007 (32.7%), 2021 (46.4%), and 2022 (46.8%) than in 2008–2012 (0.00%–6.06%), suggesting the occurrence of an epidemic in 2007, 2021, and 2022 and its disappearance in 2008–2012. However, the infection status has recently changed, with high seropositivity rates consecutively confirmed in 2021 and 2022. Logistic regression analysis was performed to investigate the relationships among the catch per unit effort (an index of animal population density), host and environmental factors, and antibody status. The catch per unit effort correlated with seropositivity in 2007. As for environmental factors, the forest area ratio had a weak influence on seroprevalence in 2007; however, the residential area ratio had a clear influence on seroprevalence in 2021 and 2022. The epidemic occurred in forested areas in 2007; nonetheless, recent raccoon population growth and habitat expansion may have caused widespread infections even around residential areas in 2021 and 2022. Continuous monitoring of the infection and reinforcement of raccoon control programs are necessary to avoid serious damage through disease transmission to sympatric native raccoon dog (Nyctereutes procyonoides) and fox (Vulpes vulpes) populations, as well as health consequences for domestic dogs (Canis familiaris).
Prediction of suicide attempt in a Swedish population‐based cohort
Authors: Lannoy Séverine , Ohlsson Henrik , Stephenson Mallory , Kendler Kenneth S. , Sundquist Jan , Sundquist Kristina , Edwards Alexis C. 
Published: December 2024

AbstractBackgroundSuicidal behaviors are prevalent public health concerns, and we need to improve our predictive ability to better inform prevention efforts.MethodsUsing nationwide longitudinal Swedish registers, we included 344,490 males and 323,177 females born 1982–1990 with information on genetic liability and environmental exposures from birth to age 16: perinatal variables, parental psychopathology (suicide attempt, substance use disorder, major depression), family status, socioeconomic difficulties, peers' psychopathology, and school grades. We conducted sex‐specific analysis and developed data‐driven predictive models including risk factors that occurred between ages 0 and 16 using structural equation modeling.ResultsIn both females and males, the best‐fitting models reveal a complex risk pathway to suicide attempt. In females, the model indicates four direct effects on suicide attempt risk: the occurrence of suicide attempt in parents during childhood (β = 0.159, 95% CI: 0.118; 0.199) and adolescence (β = 0.115, 95% CI: 0.077; 0.153), suicide attempt in peers (β = 0.068, 95% CI: 0.057; 0.079), and low academic achievement (β = 0.166, 95% CI: 0.156; 0.175). In males, aggregate genetic liability for suicide attempt (β = 0.130, 95% CI: 0.111; 0.148), suicide attempt in parents during adolescence (β = 0.099, 95% CI: 0.074; 0.124), suicide attempt in peers (β = 0.118, 95% CI: 0.108; 0.129), and low academic achievement (β = 0.61, 95% CI: 0.152; 0.171) were related to later suicide attempt. These factors also acted as mediators to explain the association between environmental exposures in childhood and later suicide attempt.ConclusionsThese findings illustrate sex‐specific pathways to suicide attempt by including risk factors that occur during the development. Results highlight the importance of genetic and family environment but also the prominent role of academic achievement.
A simulation study to assess the influence of population pharmacokinetic model selection on initial dosing recommendations of vancomycin in neonates
Authors: El Hassani Mehdi , Blouin Mathieu , Marsot Amélie 
Published: December 2024

AimsThe accuracy of model‐informed precision dosing largely depends on selecting the most appropriate population pharmacokinetic (popPK) model from many available options. This study aims to evaluate the concordance of optimal initial simulated doses among various vancomycin popPK models developed in neonates and to explore the role of predictive performance in explaining the variability in probability of target attainment (PTA).MethodsA virtual neonatal patient population was created and 26 previously externally evaluated vancomycin popPK models were used to simulate 5 different dosing regimens. For each simulated scenario, the area under the concentration–time curve and PTA were calculated to assess the agreement on optimal initial doses across the 26 models. A multiple regression was performed to explore the impact of the models' predictive performance on PTA.ResultsFor most models (15/26), there was an agreement on the optimal dosing regimen. The highest PTA being achieved by the model with the best a priori predictive performance. The multiple regression model significantly predicted mean ln‐transformed PTA, with F(2, 23) = 5.406 and P = .010, yielding an adjusted R2 of .21. PTA was significantly influenced by imprecision (P = .048) but not bias (P = .469).ConclusionIn conclusion, our study demonstrated that, despite the variability in bias and imprecision, there was a consensus on the initial optimal doses for the majority of models; however, models with superior a priori predictive performance yielded higher PTA values. Bias and imprecision alone only seem to predict a small proportion of the variability in PTA, with imprecision having a more pronounced effect.