bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk Factor for Residue After Uterine Artery Chemotherapy and Embolization in Combination with Dilatation and Curettage for Treating Caesarean Scar Pregnancy
Authors: Cheng Feng , Shan Dan , Guo Sijia , Cheng Shuang , Yang Hongwei , Han Jialin , Hu Tongxiu 
Published: June 2019

Objectives:We aimed to investigate the potential risk factors for residual lesions after uterine artery chemotherapy and embolization (UACE) in combination with dilatation and curettage (D&C) in patients with cesarean scar pregnancy (CSP).Settings:Retrospective case-control study.Methods:Univariate analysis and logistic analysis were applied to analyze these data to assess the risk factor of residue after UACE in combination with D&C.Results:Gestational age, human chorionic gonadotropin (HCG) level, and the gestation sac (GS) evagination to the bladder were the risk factors for the postoperative lesion. The most relevant was GS evagination to the bladder, followed by the preoperative HCG level and the gestational age. We defined the cut-off value of gestational age as 28 days with a sensitivity and specificity of 100 and 0, respectively.Conclusions:In cases with GS evagination to bladder and HCG of >28,113.65 mIU/ml as well as a gestational age of >28 days, the possibility of residual lesions was high.
Social Network Analysis of Dementia Wards in Psychiatric Hospitals to Explore the Advancement of Personhood in Patients with Alzheimer’s Disease
Authors: Lazzari Carlo , Kotera Yasuhiro , Thomas Hywel 
Published: June 2019

Background:
Little is known on investigating how healthcare teams in dementia wards act for
promoting personhood in persons with Alzheimer’s disease (PWA).

Objective:
The current research aimed to identify the social networks of dementia health carers promoting
the personhood of PWA in acute or long-term dementia wards in public and private psychiatric hospitals.
Methods: We used a mixed-method research approach. Ethnographic observations and two-mode Social
Network Analysis (SNA) captured the role and social networks of healthcare professionals promoting
PWA personhood, using SocNetv version 2.4. The social network graphs illustrated how professionals
participated in PWA care by computing the degree of centrality (%DC) for each professional; higher
values indicated more statistical significance of a professional role compared to others in the provision of
personhood care. The categories of personhood were biological, individual, and sociologic. Nurses, doctors,
ward managers, hospital managers, clinical psychologists, occupational therapists, care coordinators,
physiotherapists, healthcare assistants, and family members were observed if they were promoting PWA
personhood.

Method:
We used a mixed-method research approach. Ethnographic observations and two-mode Social Network Analysis (SNA) captured the role and social networks of healthcare professionals promoting PWA personhood, using SocNetv version 2.4. The social network graphs illustrated how professionals participated in PWA care by computing the degree of centrality (%DC) for each professional; higher values indicated more statistical significance of a professional role compared to others in the provision of personhood care. The categories of personhood were biological, individual, and sociologic. Nurses, doctors, ward managers, hospital managers, clinical psychologists, occupational therapists, care coordinators, physiotherapists, healthcare assistants, and family members were observed if they were promoting PWA personhood.

Results:
The highest %DC in SNA in biological personhood was held by the ward nurses (36%), followed
by the ward doctors (20%) and ward managers (20%). All professional roles were involved in 16%
of cases in the promotion of individual personhood, while the hospital managers had the highest %DC
(33%) followed by the ward managers and nurses (27%) in the sociologic personhood.

Conclusion:
All professional roles were deemed to promote PWA personhood in dementia wards, although
some limitation exists according to the context of the assessment.
2-Mercapto Benzothiazole Derivatives: As Potential Leads for the Diabetic Management
Authors: Ullah Saeed , Mirza Salma , Salar Uzma , Hussain Shafqat , Javaid Kulsoom , Khan Khalid M. , Khalil Ruqaiya , Atia-tul-Wahab  , Ul-Haq Zaheer , Perveen Shahnaz , Choudhary Muhammad I. 
Published: June 2019

Background:
Results of our previous studies on antiglycation activity, and the noncytotoxicity
of 2-mercapto benzothiazoles, encouraged us to further widen our investigation towards
the identification of leads against diabetes mellitus.

Methods:
33 derivatives of 2-mercapto benzothiazoles 1-33 were evaluated for in vitro α-
glucosidase inhibitory activity. Mode of inhibition was deduced by kinetic studies. To predict the
interactions of 2-mercapto benzothiazole derivatives 1-33 with the binding pocket of α-glucosidase
enzyme, molecular docking studies were performed on the selected inhibitors.

Results:
Compounds 2-4, 6-7, 9-26, 28 and 30 showed many folds potent α-glucosidase inhibitory
activity in the range of IC50 = 31.21-208.63 μM, as compared to the standard drug acarbose (IC50 =
875.75 ± 2.08 μM). It was important to note that except derivative 28, all other derivatives were
also found previously to have antiglycating potential in the range of IC50 = 187.12-707.21 μM.

Conclusion:
A number of compounds were identified as dual nature as antiglycating agent and α-
glucosidase inhibitors. These compounds may serve as potential lead candidates for the management
of diabetes mellitus.
Antibiotic Abuse Induced Histopathological and Neurobehavioral Disorders in Mice
Authors: Helaly Ahmed Mohamed Nabil , El-Attar Yomna Ahmed , Khalil Mahmoud , Ahmed Ghorab Doaa Shams El-Din , El- Mansoury Adel Mahmoud 
Published: June 2019

Introduction:
Antibiotic abuse is a common phenomenon in Egypt as medications are prescribed
without supervision. It is suggested that the excess use of antibiotics modifies the gut microbiota
and plays a role in the development of neurological and psychiatric disorders.

Objectives:
The aim of the present study was to use bulb-c mice as models for curam (amoxicillin
/clavulanic acid) abuse compared to the locally acting neomycin model, then restoring the probiotic balance
to look at the possible effects on the animal brains.

Methods:
The results showed early excitable brains demonstrated by S100b immunohistochemistry in
both cortexes and hippocampuses of neomycin-treated mice. Staining with PAS stain showed no suggested
neurodegenerative changes. Treatment with probiotics improved the S100b immunohistochemistry
profile of the curam group partially but failed to overcome the neuroinflammatory reaction detected
by hematoxylin and eosin stain. Curam was possibly blamed for the systemic effects.

Results:
The neurobehavioral tests showed delayed impairment in the open field test for the curam group
and impaired new object recognition for the neomycin group. These tests were applied by video recording.
The neurobehavioral decline developed 14 days after the end of the 3-week antibiotic course. Unfortunately,
curam abuse induced animal fatalities.

Conclusion:
Antibiotic abuse has a neurotoxic effect that works by both local and more prominent systemic
mechanisms. It can be said that antibiotic abuse is a cofactor behind the rise of neuropsychiatric
diseases in Egypt.
Effects of Treatment of Metabolic Acidosis in CKD
Authors: Navaneethan Sankar D. , Shao Jun , Buysse Jerry , Bushinsky David A. 
Published: June 2019

Background and objectives
Metabolic acidosis is associated with progression of CKD and has significant adverse effects on muscle and bone. A systematic review and meta-analysis was conducted to evaluate the benefits and risks of metabolic acidosis treatment with oral alkali supplementation or a reduction of dietary acid intake in those with CKD.

Design, setting, participants, & measurements
MEDLINE, Embase, and Cochrane CENTRAL were searched for relevant trials in patients with stage 3–5 CKD and metabolic acidosis (<22 mEq/L) or low-normal serum bicarbonate (22–24 mEq/L). Data were pooled in a meta-analysis with results expressed as weighted mean difference for continuous outcomes and relative risk for categorical outcomes with 95% confidence intervals (95% CIs), using a random effects model. Study quality and strength of evidence were assessed using Cochrane risk of bias and the Grading of Recommendations Assessment, Development and Evaluation criteria.

Results
Fourteen clinical trials were included (n=1394 participants). Treatment of metabolic acidosis with oral alkali supplementation or a reduction of dietary acid intake increased serum bicarbonate levels (14 studies, 1378 patients, mean difference 3.33 mEq/L, 95% CI, 2.37 to 4.29) and resulted in a slower decline in eGFR (13 studies, 1329 patients, mean difference −3.28 ml/min per 1.73 m2, 95% CI, −4.42 to −2.14; moderate certainty) and a reduction in urinary albumin excretion (very-low certainty), along with a reduction in the risk of progression to ESKD (relative risk, 0.32; 95% CI, 0.18 to 0.56; low certainty). Oral alkali supplementation was associated with worsening hypertension or the requirement for increased antihypertensive therapy (very-low certainty).

Conclusions
Low-to-moderate certainty evidence suggest that oral alkali supplementation or a reduction in dietary acid intake may slow the rate of kidney function decline and potentially reduce the risk of ESKD in patients with CKD and metabolic acidosis.
Deteksi Tingkat Kematangan Buah Tomat dengan Metode Fuzzy Logic Menggunakan Modul Kamera Raspberry PI
Authors: Muthiati Nadia , Herlinawati Herlinawati , Sulistiyanti Sri Ratna , Purwiyanti Sri 
Published: June 2019

Intisari — Proses pemanenan buah tomat dapat dilakukan menggunakan metode visual dengan memperhatikan warna atau ukuran dari buah. Kemajuan teknologi menggunakan bantuan komputer membuat pemanenan dan pendeteksian kematangan buah tomat semakin mudah. Informasi kematangan buah tomat dapat diperoleh dengan cara pengolahan citra dengan bantuan fuzzy logic menggunakan metode Tsukamoto. Pada penelitian ini beberapa sampel buah tomat diambil nilai RGB melalui pengolahan citra sesuai dengan tingkat kematangannya, diantaranya mentah, setengah matang, dan buah matang. Setelah nilai RGB didapat maka akan diproses ke dalam fuzzy logic untuk mendapatkan informasi kematangan melalui aturan-aturan yang telah dibuat dan diintegrasikan menggunakan Raspberry Pi. Hasil penelitian ini menunjukan bahwa kondisi yang baik untuk melakukan pendeteksian buah tomat salah satunya yaitu pada kondisi indoor 100 Lux berlatar belakang gelap. Hal ini mungkin dikarenakan tidak terdapat pantulan cahaya berlebih sehingga citra yang diambil nilai RGBnya tidak terlalu tinggi dan mengurangi terjadinya kesalahan pembacaan informasi kematangan dalam proses fuzzy logic.Kata kunci — Image Processing, Fuzzy Logic, Modul Kamera Raspberry Pi.Abstract — The process of harvesting tomatoes is usually done by the visual method by looking at the color or the size of the fruit. Technological advancements by using computer assistance make harvesting and detecting the ripening process of tomatoes easier. The information of the process of Tomato’s ripening can be obtained by the image processing by using Tsukamoto Fuzzy-Logic. In this research some samples of tomatoes’ RGB values were taken through image processing in accordance with the ripening level, between unripe, under-ripe, and ripe fruit. After the RGB value is obtained, it will be processed into fuzzy logic to obtain the ripening level information through rules that have been created and integrated by using Raspberry-Pi. The result of this research indicates that a good condition for detecting tomatoes is in 100 Lux conditions with dark background. This might be because there is no excessive light reflection, so that the RGB value of the image is not too high and reduces the error of reading the ripening level in the fuzzy logic process.Keywords— Image Processing, Fuzzy Logic, Raspberry Pi Camera Module.
Peningkatan Kemampuan Bahasa Inggris Kelompok Wanita Tani (KWT) di Sukaraja Sukabumi
Authors: Susilawati Lusi , Hestiana Siska 
Published: June 2019

Di Sukabumi terdapat beberapa kelompok wanita tani (KWT) yang memiliki potensi untuk meningkatkan hasil produksinya. Salah satu KWT tersebut adalah KWT yang terdapat di wilayah Desa Sukaraja, yaitu kelompok pengolah dan pemasar (POKLAHSAR) Saluyu. Kelompok ini mempunyai keinginan untuk selalu berkembang, oleh karenanya pembinaan perlu dilakukan terhadap KWT tersebut. Hal ini dilakukan karena diharapkan hasil produksinya dapat dipasarkan tidak hanya untuk konsumen lokal namun juga dapat dipasarkan kepada konsumen asing. Tujuan dan target tersebut tentu saja dapat dicapai dengan sebuah metode. Metode yang dimaksud berupa pelatihan bahasa Inggris. Pelatihan tersebut dilaksanakan dalam beberapa tahap yang diawali dengan sosialisasi, pemilihan peserta, pembuatan modul, pelatihan, monitoring dan evaluasi, dan penyusunan laporan. Hasil dari kegiatan pelatihan ini adalah meningkatnya pengetahuan anggota KWT Poklahsar Saluyu terutama pengetahuan mengenai istilah-istilah yang berhubungan dengan pengolahan ikan dalam bahasa Inggris dan dapat melakukan percakapan sederhana dengan menggunakan bahasa Inggris yang dibuktikan dengan sertifikat
INTERNET MERETAS KEBUNTUAN ADMINISTRASI DESA CIBUNTU, PURWAKARTA
Authors: Djashan Indra Arifin , Supriatna Dicky 
Published: June 2019

Sustainable Development Goals (SDGs) merupakan agenda pembangunan dunia yang dipelopori oleh Perserikatan Bangsa-Bangsa (UN) memiliki tujuan bagi kesejahteraan umat manusia, dan melestarikan kehidupan bumi. Dengan mengacu kepada tujuan ke 4 dari tujuh belas tujuan SDG, yakni: menjamin pendidikan yang inklusif dan berkeadilan serta mendorong kesempatan belajar seumur hidup bagi semua orang. Sebagian besar mata pencaharian penduduk di desa tersebut adalah petani. Beberapa komoditas utama seperti pala, gula aren dan manggis menjadi industri rumah tangga yang kerap menjadi andalan desa tersebut. Pusat Penelitian dan Pengabdian kepada Masyarakat (P3M) STIE Trisakti bekerja sama dengan SMA Lab School Kebayoran dimana P3M berkontribusi dalam hal pengadaan dan pelatihan dasar komputer. Permasalahan yang dihadapi oleh pengelola desa Cibuntu adalah pemanfaatan teknologi sebagai sarana dalam kegiatan administrasi yang cepat, mudah dan efisien. Metode pengabdian masyarakat yang diterapkan meliputi: ceramah, presentasi, studi kasus, simulasi dan evaluasi. Tujuan pengabdian masyarakat memberikan pelatihan dan penyuluhan akses kecepatan sambungan internet, instalasi jaringan sederhana, dan penanganan atas serangan virus dengan harapan pekerjaan administrasi dan laporan perkembangan desa dapat diaplikasikan dengan mudah dan cepat. Target dan luaran yang hendak dicapai adalah membangun infrastruktur jaringan sederhana, mendorong kesempatan belajar bagi setiap warga desa, dan membina inovasi yang berkelanjutan. Tentunya bukan sekedar ilmu dan pengetahuan yang disampaikan, tetapi juga bantuan dua unit komputer sebagai wujud untuk kemudahan bagi perangkat desa Cibuntu dalam melaksanakan kegiatan operasional sehari-hari.

Kata kunci: Sustainable Development Goals, Desa Cibuntu Purwakarta, STIE Trisakti, Pengabdian Masyarakat, P3M
PENINGKATAN STATUS GIZI DAN KESEHATAN ANAK BALITA MELALUI PENINGKATAN PERILAKU SEHAT IBU DI BANGUNREJO LAMPUNG TENGAH
Authors: Berawi Khairun Nisa 
Published: June 2019

Berdasarkan survei yang dilakukan Kemenkes RI melalui riskesdas didapatkan prevalensi balita stunting di Indonesia meningkat dari 36,8% (2007) menjadi 37,2% tahun 2013. Kabupaten Lampung Tengah, Lampung didapatkan kejadian stunting paling tinggi yaitu 52,7% berdasarkan Profil Kesehatan Provinsi Lampung tahun 2015. Penurunan prevalensi balita stunting menjadi salah satu prioritas pembangunan. Stunting terjadi akibat kurangnya asupan dan penyerapan nutrisi terutama pada 1000 hari pertama kehidupan dan merupakan masalah multifaktorial. Stunting memerlukan kerjasama lintas institusi termasuk managemen kesehatan keluarga yang membutuhkan peran ibu sebagai pengelola rumah tangga. Peningkatan perilaku sehat ibu diharapkan mampu meningkatkan status gizi dan kesehatan balita untuk mencegah stunting pada Balita. Kegiatan dilaksanakan melalui penyuluhan mengenai managemen balita sehat dan edukasi perilaku hidup bersih dan sehat pada ibu ibu PKK di Kecamatan Bangun Rejo, Lampung Tengah, yang diharapkan menjadi role model ibu sehat. Hasil pengabdian didapatkan peningkatan pengetahuan peserta berdasarkan hasil pre test diketahui 50, 55% peserta mempunyai pengetahuan kurang dan 49,45% peserta telah memiliki pengetahuan yang cukup dan hasil post test, diketahui bahwa 20% peserta cukup paham, 50% telah memiliki pengetahuan yang baik dan 30% sangat baik. Diharapkan peningkatan pengetahuan dan edukasi yang diberikan akan membantu peningkatan perilaku sehat ibu sehingga mampu mencegah stunting pada balita.

Kata kunci: Balita stunting, managemen kesehatan keluarg, status gizi dan kesehatan balita
Histological Gingival Assessment after Conventional and Laser Gingivectomy
Authors: Kazakova Rada T. , Tomov Georgi T. , Kissov Christo K. , Vlahova Angelina P. , Zlatev Stefan Ch. , Bachurska Svitlana Y. 
Published: June 2019

Abstract
Background: Gingivectomy is a procedure often performed in everyday clinical practice using numerous instruments.
Aim: To evaluate and compare the gingival cut surface after gingivectomy with 6 different surgical instruments – a surgical scalpel, an Er:YAG laser, a CO2 laser, a ceramic bur, an electrocautery device, and a diode laser.
Materials and methods: Gingivectomy using the above listed instruments was performed in 18 patients. The histological samples excised with a surgical scalpel were assigned as a control group and the other five types – as test groups. The following histological parameters were measured: coagulation layer thickness (in μm); presence or absence of a microscopic rupture and presence or absence of hemostasis in-depth.
Results: The best instrument of the above listed ones which demonstrated excellent results is the CO2 laser. The Er:YAG laser has a thin coagulation layer and lack of hemostasis in-depth. The diode laser has the widest coagulation layer which is an advantage from a clinical point of view. Electrocautery proved to be as effective as the diode laser, but it should not be used around metal restorations. The ceramic bur has less pronounced hemostasis in-depth.
Conclusions: Modern dentistry uses a wide variety of methods that are designed to be applied in everyday practice. Good knowledge of the ways to use them, their advantages and disadvantages is essential to obtaining the optimal result depending on the clinical case.
Performances of Diagnostic Methods in Gastroesophageal Reflux Disease
Authors: Săraru Elena-Roxana , Peagu Răzvan , Călin-Necula Ana-Maria , Moldoveanu Alexandru , Fierbinţeanu-Braticevici Carmen 
Published: June 2019

Abstract
Gastroesophageal reflux disease (GERD) is one of the most common chronic gastrointestinal ailments worldwide, with a high prevalence and extremely costly diagnostic and therapeutic management. A hygienic-dietary regimen, accompanied by weight loss, are important factors for improving the symptoms of reflux disease. Various ways of correct diagnosis and for therapeutic management have been attempted over the years, of which themost widely used diagnostic method is empirical therapy with proton pump inhibitors. Also, questionnaires, upper digestive endoscopy with biopsies, barium radiography, ambulatory monitoring of esophageal pH, pH-impedance and esophageal manometry are widely used. Upper gastrointestinal endoscopy has a good specificity, but a low sensitivity for GERD. Also, the GERQ questionnaire has a good sensitivity and specificity in the accuracy of GERD diagnostic. Barium swallow use belongs to the past, and is recommended mostly for the detection of anatomical anomalies and not for the diagnosis of reflux disease. 24-hour ambulatory monitoring of esophageal pH is the study of choice to confirm the diagnosis of reflux disease in patients without endoscopic modifications suggestive of GERD. The association of impedance to esophageal pH monitoring is the gold standard for diagnosing GERD, making it possible to differentiate between acid reflux, weakly acid and non-acid episodes, and is also useful for diagnosing other conditions that mimic the GERD's clinical symptoms.
Plum Research and Growing in Latvia
Authors: Kaufmane Edīte , Grāvīte Ilze , Ikase Laila 
Published: June 2019

Abstract
Plums have been commercially grown in Latvia since the 19th century. Plantations expanded especially in the 1920s–1930s. At that time, many cultivars were introduced, mostly from Western Europe. After the severe winters of 1939/40, 1941/42, 1955/56, and 1978/79, the plum orchard area significantly decreased because of a lack of winter-hardy cultivars. For this reason, cultivars from Russia, Belarus, and Estonia were introduced. Among the old landraces, highly winter-hardy ‘Latvijas Dzeltenā Olplūme’ is still important. Previously it used to be productive and had good fruit quality. Unfortunately, nurseries often propagated the hardiest clones, which lacked productivity. As Latvian consumers love yellow plums, at present breeding and propagation of productive clones from old orchards is ongoing. In the mid-20th century, active plum breeding started in Latvia, crossing hardy genotypes with high quality donors. From this period ‘Lāse’ and ‘Minjona’ are still grown. Since the 1980s, plum breeding has been undedrtaken at the Institute of Horticulture. The crossing work in plums concentrated on the hexaploid group, aiming to combine large fruit size with good flavour, different time of ripening (in particular, early to medium late) and and good winter-hardiness. New cultivars include ‘Sonora’, ‘Ance’, and ‘Adelyn’, which have good quality, and productivity 20–30 kg per tree, and in some years up to 70 kg per tree.
The most widely used rootstocks are seedlings of Prunus cerasifera Ehrh. ssp. divaricata C.K. Schneid., which is more hardy that the common myrobalan plum. These rootstocks have good compatibility with most cultivars except gages, and are adapted to different soil types and are disease tolerant. Their drawback is a long growth season which reduces winter-hardiness of grafted cultivars. Also, they tend to form suckers around the stem. A hardy seedling PU-20651 (P. salicina ssp. ussuriensis × P. cerasifera) was bred at the Institute, which was shown to slightly reduce tree vigour. Testing of several Western European and Russian rootstocks did not result in their introduction into production. Trials are presently being carried out with size-reducing root-stocks originated from cultivar Wangenheim VVA-1, Weiwa, S766, and M633.
Commercial production of plums in Latvia is relatively small, as the area of orchards is the smallest among fruit trees. Plums are grown mostly for fresh consumption, with a small part for jams, yoghurt, and ice-cream additives. Fruits are sold mostly in small shops, markets and at farms. The main reason is the climate, which allows growing of a limited range of cultivars that tolerate the –30 °C winter temperatures in some years (about every five years). About 20 cultivars are grown commercially; the share of the six most popular plum cultivars is 69% of the total plum production. In recent years, plantations of new cultivars developed at our Institute have expanded, especially regarding the early ripening cultivar ‘Ance’.