bluuebunny/crossref_metadata_2025_split huggingface dataset:
Superlattice‐like Zn15Sb85/Ga30Sb70 thin films for low power and ultrafast phase change memory application
Authors: Zhang Rui , Hu Yifeng , Chou Qingqian , Lai Tianshu , Zhu Xiaoqin 
Published: December 2018

In this study, the amorphous‐to‐crystalline transitions of superlattice‐like (SLL) Zn15Sb85/Ga30Sb70 thin films were investigated by in situ film resistance measurement. The thermal stability, resistance and band gap of the SLL Zn15Sb85/Ga30Sb70 thin film perform well. The data retention temperature for 10 years increases from 177°C of [Zn15Sb85 7/Ga30Sb70 3] to 220°C of [Zn15Sb85 2/Ga30Sb70 8]. The X‐ray diffraction patterns show the presence of a large amount of Sb phase in the Zn15Sb85/Ga30Sb70 thin films, which causes a rapid phase transition. The surface morphology is observed by atomic force microscopy, which indicates that the thickness of Ga30Sb70 in the SLL thin films can affect the grain size and inhibit the crystallisation process. For the Zn15Sb85/Ga30Sb70 thin films, an ultra‐short switching time of around 2 ns is achieved. These results indicate that the SLL Zn15Sb85/Ga30Sb70 thin films have a promised application in phase change memory.
Controlled synthesis of Ag3PO4 microparticles with different morphologies and their photocatalytic degradation of rhodamine B under white light‐emitting diode irradiation
Authors: Wei Tzu‐Ting , Wu Tsunghsueh , Lin Yang‐Wei 
Published: December 2018

A facile morphological specific precipitation method by volumetric control of the precursors has been demonstrated to achieve tetrapod‐like and dodecahedron‐like Ag3PO4 microparticles, which show superior visible‐light responsive of photocatalytic activity when comparing to TiO2 (P25). This study also reveals that the tetrapod‐like Ag3PO4 microparticles exhibit significantly higher photocatalytic activity (95.6% degradation within 20 min, k: 0.1937 min−1) than the dodecahedrons (78.9% degradation within 30 min, k: 0.0593 min−1) for the degradation of rhodamine B (RhB, 10 ppm) under low‐power white light‐emitting diode irradiation (300 mW cm−2), which may be attributed to the high reactivity of {110} facets. Moreover, holes and superoxide radicals were the main reactive species involved in RhB degradation.
Analysis of the origin of water, carbon monoxide, and carbon dioxide in the Uranus atmosphere
Authors: Lara L. M. , Rodrigo R. , Moreno R. , Lampón M. 
Published: December 2018

Context. We present here an analysis of the potential sources of oxygen species in the Uranus atmosphere.
Aims. Our aim is to explain the current measurements of H2O, CO, and CO2 in the Uranus atmosphere, which would allow us to constrain the influx of oxygen-bearing species and its origin in this planet.
Methods. We used a time-dependent photochemical model of the Uranus atmosphere to ascertain the origin of H2O, CO, and CO2. We thoroughly investigated the evolution of material delivered by a cometary impact, together with a combined source, i.e. cometary impact and a steady source of oxygen species from micrometeoroid ablation.
Results. We find that an impactor in the size range ~1.2–3.5 km hitting the planet between 450 and 822 yr ago could have delivered the CO currently seen in the Uranus stratosphere. Given the current set of observations, an oxygen-bearing species supply from ice grain ablation cannot be ruled out. Our study also indicates that a cometary impact cannot be the only source for rendering the observed abundances of H2O and CO2. The scenarios in which CO originates by a cometary impact and H2O and CO2 result from ice grain sublimation can explain both the space telescope and ground-based data for H2O, CO, and CO2. Similarly, a steady influx of water, carbon monoxide, and carbon dioxide, and a cometary impact delivering carbon monoxide give rise to abundances matching the observations. The time evolution of HCN also delivered by a cometary impact (as 1% of the CO in mass), when discarding chemical recycling of HCN once it is lost by photolysis and condensation, produces a very low stratospheric abundance which could be likely non-detectable. Consideration of N2-initiated chemistry could represent a source of HCN allowing for a likely observable stratospheric mixing ratio.
Conclusions. Our modelling strongly indicates that water in the Uranus atmosphere likely originates from micrometeroid ablation, whereas its cometary origin can be discarded with a very high level of confidence. Also, we cannot firmly constrain the origin of the detected carbon monoxide on Uranus as a cometary impact, ice grain ablation, or a combined source due to both processes can give rise to the atmospheric mixing ratio measured with the Herschel Space Observatory. To establish the origin of oxygen species in the Uranus atmosphere, observations have to allow the retrieval of vertical profiles or H2O, CO, and CO2. Measurements in narrow pressure ranges, i.e. basically one pressure level, can be reproduced by different models because it is not possible to break this degeneracy about these three oxygen species in the Uranian atmosphere.
Surface abundances of CNO in Galactic O-stars: a pilot study with FASTWIND
Authors: Carneiro L. P. , Puls J. , Hoffmann T. L. , Holgado G. , Simón-Díaz S. 
Published: December 2018

Context. Rotational mixing is known to significantly affect the evolution of massive stars; however, we still lack a consensus regarding the various possible modeling approaches and mixing recipes describing this process. The empirical investigation of surface abundances of carbon, nitrogen, and oxygen (CNO) in large samples of O- and B-type stars will be essential for providing meaningful observational constraints on the different available stellar evolution models.
Aims. Setting up and testing adequate tools to perform CNO surface abundance determinations for large samples of O-type stars, by means of the fast performance, NLTE, unified model atmosphere code FASTWIND.
Methods. We have developed a set of semi-automatic tools for measuring and analyzing the observed equivalent widths of strategic optical C, N, and O lines from different ions. Our analysis strategy is based on a χ2 minimization of weighted differences between observed and synthetic equivalent widths, the latter computed from tailored model grids. We have paid special attention to the (significant) errors introduced by typical uncertainties in stellar parameters. In this pilot study, we describe these tools, and test their performance and reliability using a set of high quality spectra of a sample of 18 presumably single Galactic O-type stars with low projected rotational velocities (v sin i≲100 km s−1), and previously determined stellar parameters. In particular, we have compared the outcome of our analysis with results from existing studies and theoretical stellar evolution models.
Results. Most of our results for carbon and nitrogen agree, within the errors, with both theoretical expectations and literature values. While many cooler dwarfs display C and N abundances close to solar, some of the early- and mid-O dwarfs – and most supergiants – show significant enrichment in N and depletion in C. Our results for oxygen in late-O dwarfs are, however, unexpectedly low, possibly indicating deficiencies in the adopted oxygen model atom. For all other objects, no systematic problems in their oxygen content have been identified. Specific stars in our sample show peculiarities in their abundances, and we suggest hypotheses regarding their origin.
Conclusions. Our method is (almost) ready to be applied to large samples of late and mid O-type stars – although the oxygen model atom needs to be improved and carefully tested first. For early O-type stars (O4 and hotter), a simultaneous UV analysis seems to be inevitable, due to the scarcity and weakness of optical C and O lines. This will necessarily imply a more complex modeling, additionally accounting for the effects of X-rays from wind-embedded shocks and wind inhomogeneities.
Aktuelle Trends in der flexiblen Ureterorenoskopie – ein Update
Authors: Hein Simon , Schönthaler Martin , Suarez-Ibarrola Rodrigo , Müller Philippe-Fabian , Schoeb Dominik , Miernik Arkadiusz 
Published: December 2018

ZusammenfassungDie flexible Ureterorenoskopie (fURS) kann als „urotechnologische“ Erfolgsgeschichte bezeichnet werden. Seit der Einführung der fURS in die Harnsteintherapie wurde diese immer weiter technisch verbessert, was zu exzellenten klinischen Ergebnissen bei niedrigen Komplikationsraten führte. In den letzten Jahren prägte insbesondere die Einweg-Ureterorenoskopie die Landschaft der urologischen Endoskopie. Bei genauerer Betrachtung ist diese Entwicklung jedoch keine genuine Innovation, sondern vielmehr eine weiterführende Optimierung, die primär zur Vereinfachung innerbetrieblicher Abläufe (keine Sterilisation, keine Reparaturen) sowie zur Verhinderung der Keimübertragung bei insuffizient aufbereiteten Arbeitskanälen führt. Neue Technologien wie eine automatisierte Laserlithotripsie, intrarenale Temperatur- und Druckmessung warten noch auf ihre Markteinführung und den Einsatz bei der fURS. Diese hätten das Potenzial die endoskopische Steintherapie einen weiteren entscheidenden Schritt voranzubringen.
Rechtskreisübergreifende Kooperation in einem Gemeindepsychiatrischen Zentrum
Authors: Schwarz Julian , Stöckigt Barbara , Berghöfer Anne , von Peter Sebastian , Brückner Burkhart 
Published: December 2018

Zusammenfassung
Ziel Untersucht werden die Kooperationsbedingungen der beteiligten Akteure in einem Modellprojekt zur Koordination von SGB V- und XII-Leistungen.
Methode Interviews mit gemeindepsychiatrischen Akteuren aus der Modellregion und qualitativ-inhaltsanalytischer Auswertung.
Ergebnisse Ähnliche Steuerungsziele und Vergütungsmodelle sind Voraussetzungen rechtskreisübergreifender Zusammenarbeit. Gemeindeferne Versorgung sowie (infra-)strukturelle Defizite wirken sich hinderlich aus.
Schlussfolgerungen Die Implementierung sektorenübergreifender Finanzierung für Behandlungs- als auch Eingliederungsleistungen sind ein erster Schritt in Richtung rechtskreisübergreifender Kooperation.
Psychische Symptombelastung bei Asylsuchenden in Abhängigkeit vom Aufenthaltsstatus
Authors: Winkler Johanna G. , Brandl Eva J. , Bretz H. Joachim , Heinz Andreas , Schouler-Ocak Meryam 
Published: December 2018

Zusammenfassung
Ziele der Studie Untersuchung der Sicht von Asylbewerbern auf rechtliche Situation, Asylverfahren und Lebensbedingungen und deren Einfluss auf psychische Belastungen.
Methode 650 Asylbewerber in Berlin erhielten einen Fragebogen.
Ergebnisse 76,3 % (N = 496) beantworteten den Fragebogen vollständig. Von diesen hatten 74,6 % Symptome einer psychischen Erkrankung, und dies mit signifikantem Zusammenhang zu unsicherem Aufenthaltsstatus. Sehr belastete Personen nahmen Hilfsangebote, integrationsfördernde Maßnahmen und ihre Rechte im Asylverfahren weniger wahr. In unserer Stichprobe befanden sich nur 11,6 % der Asylbewerber mit krankheitswertiger psychischer Symptomatik in psychiatrischer Behandlung.
Schlussfolgerung Die Daten zeigen die hohe Relevanz psychischer Belastungen bei Geflüchteten.
Lithopedion in a Geriatric Patient
Authors: Ricaurte Sossa Andrés , Bolaños Henry , Ricaurte Fajardo Andrés , Burgos Ángela Camila , Garcia Valentina , Muñoz Paola , Rosselli Diego 
Published: December 2018

AbstractLithopedion (lithos = rock and paidion = child) is a rare condition that only occurs in 1.5 to 1.8% of extrauterine pregnancies and in 0.00045% of all pregnancies. It consists of an ectopic pregnancy in which the fetus dies but cannot be reabsorbed by the mother's body, which then coats it in a calcium-rich substance. We present the case of a 77-year-old woman with an incidental diagnosis of a lithopedion, which had been retained in her left pelvis for presumably 40 years.
Health Information Exchange in Emergency Medical Services
Authors: Martin Thomas , Ranney Megan , Dorroh James , Asselin Nicholas , Sarkar Indra 
Published: December 2018

Background The Office of the National Coordinator for Health Information Technology has outlined the benefits of health information exchange in emergency medical services (EMSs) according to the SAFR model—search, alert, file, and reconcile—developed in collaboration with the California Emergency Medical Services Authority.
Objective This scoping review aims to identify and characterize progress toward the adoption of prehospital health information exchange, as reported in the peer-reviewed literature.
Methods A structured review of literature in MEDLINE-indexed journals was conducted using the “Electronic Health Records” topic-specific query, the “Emergency Medical Services” Medical Subject Headings descriptor, and a prehospital identifier.
Results Our initial search yielded 368 nonduplicative, English-language articles; 131 articles underwent full-text review and 11 were selected for analysis according to pre-established inclusion criteria. Original research was thematically grouped according to the SAFR model.
Conclusion Within isolated systems, there has been limited progress toward the adoption of prehospital health information exchange. Interoperability, accurate match algorithms, security, and wireless connectivity have been identified as potential barriers to adoption. Additional research is required to evaluate the role of health information exchange within EMSs.
Ruptured Renal Artery Aneurysm in a Pregnant Woman: Case Report and Literature Review
Authors: Souza Adriane Castro de , Ueda Caio Henrique Yoshikatsu , Matsubara Denise Hiromi , Glir João Raphael Zanlorensi 
Published: December 2018

AbstractRenal artery aneurysms (RAAs) are rare and usually asymptomatic; ∼ 90% of them are unilateral. Once diagnosed during pregnancy, they may rupture, presenting a high maternal-fetal risk. The present study reports the case of a 32-year-old pregnant woman with a 30-week gestational age and a ruptured unilateral RAA.
A Female Patient with Xq28 Microduplication Presenting with Myotubular Myopathy, Confirmed with a Custom-Designed X-array
Authors: Mitrakos Anastasios , Sofokleous Christalena , Papadimas George , Fryssira Helena , Kitsiou-Tzeli Sofia , Tzetis Maria , Kosma Konstantina 
Published: December 2018

AbstractX-linked myotubular myopathy (XLMTM) is a rare inherited neuromuscular disorder associated with mutations in the MTM1 gene on the Xq28 region. We report a severely affected girl with XLMTM, caused by maternally inherited 661 kb Xq28 microduplication identified by chromosomal microarray analysis and confirmed also on DNA from muscle biopsy with a custom-designed X-chromosome-specific microarray. X-inactivation analysis revealed a skewed inactivation pattern on the proband's muscle biopsy. Muscle biopsy histopathology was indicative of increased variability in fiber diameter, marked and diffuse endomysial proliferation of adipose and connective tissues, as well as predominance of type 1 fibers.
Trigeminal Cave Brain Metastasis from Prostate Adenocarcinoma: Case Report and Review of the Literature
Authors: Zanatta João , Zanella Laisa , Kurtz Guilherme , Gabardo Bárbara , Roman Alex , Pastorello Júlia 
Published: December 2018

The present study presents the case of a 66-year-old patient diagnosed with prostate adenocarcinoma 4 years earlier and treated with prostatectomy, radiotherapy, chemotherapy and hormone therapy but still displaying high prostate-specific antigen (PSA) levels. The patient complaints were double vision and headaches. Upon physical examination, he displayed 6th cranial nerve paresis and 5th cranial nerve paresthesia. A magnetic resonance imaging (MRI) exam was performed, which revealed a mass on the right trigeminal cave. The patient underwent surgical removal of the tumor, and the pathological analysis of the specimen established metastatic prostate cancer as the diagnosis.Brain metastases from prostate cancer are extremely rare and mark advanced disease, with immune system failure and blood-brain barrier breach. Prostate-specific antigen levels do not correlate with the possibility of metastatic disease. Prostate adenocarcinoma is the histologic type most commonly associated with brain metastases, with the meninges being more frequently affected, followed by the brain parenchyma. The neurological symptoms more often displayed are non-focal, such as headaches and mental confusion. Surgery associated with radiotherapy is the most validated treatment.
Monogene Formen der Adipositas beim Menschen
Authors: Herrmann G. , Wabitsch M. , von Schnurbein J. 
Published: December 2018

ZusammenfassungEs gilt Patienten mit sehr seltenen Formen der monogenen Adipositas zu identifizieren um ihnen eine optimierte oder bestenfalls sogar kausale Therapie anbieten zu können. Hinweise für eine monogene Adipositasform sind insbesondere extreme Adipositas, frühkindlicher Beginn der Adipositas, sowie auffälliges Essverhalten mit Hyperphagie, ausgeprägtem nahrungssuchendem Verhalten und fehlendem Sättigungsgefühl. Mutationen in Genen, die den Leptin-Melanocortin-Signalweg betreffen, verursachen die wichtigsten Formen der monogenen Adipositas. Dabei sind Mutationen im Melanocortin-4-Rezeptor Gen (MC4R) am häufigsten. Zu einer ausgeprägten frühkindlichen Adipositas kommt es bei autosomal rezessiv vererbten Mutationen in den Genen für Leptin (LEP), Leptinrezeptor (LEPR), Proopiomelanocortin (POMC) und Prohormonkonvertase 1/3 (PCSK1). Eine kausale Therapie ist bei biologisch inaktivem Leptin oder Leptinmangel durch die Gabe von humanem rekombinantem Leptin verfügbar. Zudem gibt es mit dem MC4R -Agonisten (Setmelanotide) eine kausale Therapieoption für Patienten mit POMC-Mutation. Für Patienten mit Mutationen in MC4R, LEPR, PCSK1 finden aktuell klinische Studien hierzu statt, so dass in Zukunft eine kausale Therapie denkbar ist.
Investigating Syntactic Complexity in EFL Learners' Writing across Common European Framework of Reference Levels A1, A2, and B1
Authors: Khushik Ghulam Abbas , Huhta Ari 
Published: December 2018

AbstractThe study investigates the linguistic basis of Common European Framework of Reference (CEFR) levels in English as a foreign language (EFL) learners’ writing. Specifically, it examines whether CEFR levels can be distinguished with reference to syntactic complexity (SC) and whether the results differ between two groups of EFL learners with different first languages (Sindhi and Finnish). This sheds light on the linguistic comparability of the CEFR levels across L1 groups. Informants were teenagers from Pakistan (N = 868) and Finland (N = 287) who wrote the same argumentative essay that was rated on a CEFR-based scale. The essays were analysed for 28 SC indices with the L2 Syntactic Complexity Analyzer and Coh-Metrix. Most indices were found to distinguish CEFR levels A1, A2, and B1 in both language groups: the clearest separators were the length of production units, subordination, and phrasal density indices. The learner groups differed most in the length measures and phrasal density when their CEFR level was controlled for. However, some indices remained the same, and the A1 level was more similar than A2 and B2 in terms of SC across the two groups.
Predicting Risk of Postoperative Disease Recurrence in Crohn’s Disease: Patients With Indolent Crohn’s Disease Have Distinct Whole Transcriptome Profiles at the Time of First Surgery
Authors: Cushing Kelly C , Mclean Richard , McDonald Keely G , Gustafsson Jenny K , Knoop Kathryn A , Kulkarni Devesha H , Sartor R Balfour , Newberry Rodney D 
Published: December 2018

Abstract

Background
Assessing risk of Crohn’s disease (CD) recurrence following ileocolic resection (ICR) is necessary to optimize medical management and prevent long-term complications. This study aimed to identify noninvasive markers that could predict postoperative disease activity.

Methods
Inclusion criteria were a diagnosis of CD, first ICR, interval colonoscopy, and whole transcriptome array meeting quality control standards. Demographic and clinical data were obtained from the electronic medical record. RNA extraction and human transcriptome microarray were performed on noninflamed ileal margins from operative specimens. Clinical data and random forest were analyzed in R. Principal components analysis, hierarchical clustering, and pathway enrichment were performed in Partek.

Results
Sixty-five patients completed the study, and 5 were excluded from analysis due to extreme variability on whole transcriptome analysis. Unsupervised hierarchical clustering revealed that patients with an i0 Rutgeerts score generally segregated from all others. In anti-TNF-naïve patients, unsupervised hierarchical clustering revealed complete segregation of patients with an i0 score. Reduced escalation in therapy and continued mucosal remission, consistent with indolent disease, were seen in the 4 years following surgery. Random forest identified 30 transcripts differentiating i0 patients from the other groups. Pathway enrichment highlighted toll-like receptor, NOD-like receptor, and TNF signaling. This transcriptome signature did not identify i0 anti-TNF-exposed patients. However, anti-TNF-exposed patients with indolent postoperative courses were found to have a transcriptome signature distinct from those with aggressive disease.

Conclusions
Anti-TNF-naïve and -exposed patients have unique expression profiles at the time of surgery, which may offer predictive value in assessing the risk of nonrecurrence.
Vaccination Guidelines for Patients with Immune-Mediated Disorders on Immunosuppressive Therapies—Executive Summary
Authors: Papp Kim A , Haraoui Boulos , Kumar Deepali , Marshall John K , Bissonnette Robert , Bitton Alain , Bressler Brian , Gooderham Melinda , Ho Vincent , Jamal Shahin , Pope Janet E , Steinhart A Hillary , Vinh Donald C , Wade John 
Published: December 2018

Abstract
The use of immunosuppressive therapies for immune-mediated disease (IMD) is associated with an elevated risk of infections and related comorbidities. While many infectious diseases can generally be prevented by vaccines, immunization rates in this specific patient population remain suboptimal, due in part to uncertainty about their efficacy or safety under these clinical situations. To address this concern, a multidisciplinary group of Canadian physicians with expertise in dermatology, gastroenterology, infectious diseases and rheumatology developed evidence-based clinical guidelines on vaccinations featuring 13 statements that are aimed at reducing the risk of preventable infections in individuals exposed to immunosuppressive agents.
Evaluating Lung Cancer Screening Uptake, Outcomes, and Costs in the United States: Challenges With Existing Data and Recommendations for Improvement
Authors: Rai Ashish , Doria-Rose V Paul , Silvestri Gerard A , Yabroff K Robin 
Published: December 2018

AbstractThe National Lung Screening Trial (NLST) reported substantial reduction in lung cancer mortality among high-risk individuals screened annually with low-dose helical computed tomography (LDCT). As a result, the US Preventive Services Task Force issued a B recommendation for annual LDCT in high-risk individuals, which requires private insurers to cover it without cost-sharing. The Medicare program also covers LDCT for high-risk beneficiaries without cost-sharing. However, the NLST findings may not be generalizable to the community setting because of differences in patients, providers, and practices participating in the NLST. Thus, examining uptake of LDCT screening in community practice is critical, as is evaluating the immediate and downstream outcomes of screening, including false-positive scans, follow-up examinations and adverse events, costs, stage of disease at diagnosis, and survival. This commentary presents an overview of the landscape of the data resources currently available to evaluate the uptake, outcomes, and costs of LDCT screening in the United States. We describe the strengths and limitations of existing data sources, including administrative databases, surveys, and registries. Thereafter, we provide recommendations for improving the data infrastructure pertaining to three overarching research areas: receipt of guideline-consistent screening and follow-up, weighing benefits and harms of screening, and costs of screening.