bluuebunny/crossref_metadata_2025_split huggingface dataset:
RISK GROUPS FOR PREGNANCY HYPERTENSIVE DISORDERS DEVELOPMENT
Authors: Shakhbazova N. A. 
Published: May 2018

Aim. Development of clinical, anamnestic, immunological and instrumental prognostic markers of high and low risk of gestational hypertensive disorders.Material and methods. A range of risk factors was assessed in 220 pregnant women with hypertensive states (main group) and 50 healthy pregant women (control group). In the pregnant, clinical and anamnestic risk factors of preeclampsia were assessed (age, parity, anamnesis of hypertensive disorders, extragenital diseases, etc.), autoantibodies to 12 antigenes (by ELI-P test), placental growth factor (PGF) and resistance index (RI) in uterus arteries, by Doppler.Results. During the study, it was found that clinical and anamnestic factors of high risk of pre-eclampsia are: first pregnancy, chronic hypertension, extragenital pathology in woman, anamnesis of pre- and eclampsia, combination of three and more factors. Preclinical immunological predictors of high risk of pre-eclampsia in the 1st trimester are high titre of autoantibodies to S-100, B-2QP, ANCA (range -65 to +94 units), combined raise of three kinds of antibodies, immunity suppression, PGF level in the blood 50-100 pg/mL — for pre-eclampsia, up to 50 pg/mL — for fetal development delay. Doppler markers of high risk of pre-eclampsia: increase of RI up to 0,60 and dicrotic notch in both uterine arteries; RI increase 0,61-0,70 with one dicrotic notch only in one uterine artery; increase of RI more than 0,70 and no dicrotic notch.Conclusion. The most useful and predictive for pre-eclampsia are clinical and anamnestic, as immunological predictors that are revealed within 15 weeks of pregnancy. Instrumental prognostic markers that are explored after 20 weeks are useful for prognosis prediction on possible pre-eclampsia development and for control of treatment efficacy.
SPECIFICS OF NEUROHUMORAL ACTIVITY AND CLINICAL PRESENTATION OF MASKED ARTERIAL HYPERTENSION IN YOUNG MALES
Authors: Lyamina N. P. , Kosareva A. V. , Tsareva O. E. , Senchikhin V. N. , Lipchanskaya T. P. , Shkrobova N. V. 
Published: May 2018

Aim. To assess the neurohumoral state, specifics of clinical presentation, prevalence and prominence of cardiovascular and behavioral risk factors in males of young age with masked arterial hypertension (MAH).Material and methods. To the full coverage screening study, 643 participants included, age 18-30 y. o. (mean age 22). Complete clinical and laboratory, instrumental assessments performed, with analysis of neurohumoral activity by the levels of adrenaline, noradrenaline, angiotensin II. All participants were selected to groups: MAH (n=61), manifest AH (n=46), normotonics (n=536). Diagnostics of MAH was done in case of positive test of 30 second respiration pause and 24 hour blood pressure (BP) monitoring.Results. In males, MAH was found in 9,5% cases, manifest AH in 7,1%, normotonia in 83,4%. In MAH and manifest AH participants the level of adrenaline was higher than in normotonics: 4,55 pM/L [3,53; 5,1], 6,25 pM/L [4,75; 8,65] and 2,1 pM/L [1,2; 4,5], respectively. Males with MAH had almost 2 times higher level of noradrenaline (19,5 pM/L [18,8; 22,8]) comparing to “normotonics” (8 pM/L [6; 12,1]) and 1,5 times higher than in manifest AH (13,1 pM/L [11,5; 14,4]). Angiotensin II assessment showed that in MAH males it was higher (18,5 pM [15,75; 21,9]), than in normotonics (15,7 pM [13;18,3]), but lower than in manifest AH (20,15 pM [18,9; 21,9]). Food related behavior assessment as of a factor of sodium overconsumption, the higher values were found in MAH patients and in manifest AH (50% and 50%) comparing to normotonics (25%). Early age of smoking beginning found in 28% of MAH males, more prevalent than in normotonics (24%) and manifest AH (15%).Conclusion. In young males MAH is revealed more often than manifest AH. Development of MAH in young males is related to hypersympathicity with raised catecholamines level, disordered 24 hour rhythm “non-dipper”, disorder of BP variability and higher smoking level, than in normotonics.
COMPARISON OF INFLUENCE OF VARIOUS REGIMENS OF DRUG INTAKE ON 24 HOUR bLOOD PRESSURE, CENTRAL AORTIC PRESSURE AND VASCULAR WALL STIFFNESS IN SYSTEMIC HYPERTENSION PATIENTS WITH ISCHEMIC STROKE
Authors: Skibitsky V. V. , Fendrikova A. V. , Opolskaya S. V. 
Published: May 2018

Aim. To assess and compare the efficacy of combination antihypertension drugs influence with various dosage regimens during 24 hour, on the parameters of daily blood pressure (BP) profile, central aortic pressure (CAP) and vessel wall stiffness in arterial hypertension (AH) patients with ischemic stroke (IS).Material and methods. To the study, 177 AH patients included, with IS within last 4 weeks. All patients were randomized to 3 groups depending on the regimen of antihypertensive drugs combination intake during 24 hours. At baseline and in 12 months of therapy all patients underwent 24 hour BP monitoring (ABPM), CAP measurement and vessel wall stiffness evaluation. Results. In 8 weeks of antihypertension therapy, target pressure level achievement was significantly more common in b. i.d. valsartan (group 3) comparing to once daily in the morning (group 1) or evening (group 2) (p<0,05). In all groups there were statistically significant positive changes in ABPM, CAP and stiffness. Also, in the group 2 there was significantly (p<0,05) more prominent decrease of the main ABPM, CAP and stiffness parameters than in the group 1. Valsartan b. i.d. led to significantly more prominent (p<0,05) improvement of the main ABPM, CAP and stiffness parameters improvement comparing to both variants of its once daily regimens. In 12 months of chronopharmacotherapy, in all groups, there was significant (p<0,05) increase of “dipper” 24 hour BP profile patients. Differences of the groups of “dippers” and “non-dippers” by the 12th month of treatment were significant for 3rd and 1st (p=0,0004), 3rd and 2nd (p=0,04) groups with the benefit for group 3.Conclusion. Two times a day or only evening intake of valsartan with thiazidelike diuretic in the morning facilitated more significant improvement of the main parameters of ABPM, CAP and vascular wall rigidity comparing to just morning intake. B.i.d. valsartan regimen led to significantly (p<0,05) more commonly reached target BP level, improved normalization of 24 hour BP in most of patients, led to more significant improvement of the main ABPM, CAP and vascular stiffness parameters comparing to once daily morning or evening regimen.
TAURIN INFLUENCE ON CLINICAL COURSE OF STAbLE ANGINA IN POSTINFARCTION CARDIOSCLEROSIS PATIENTS
Authors: Vasilieva I. S. , Rezvan V. V. 
Published: May 2018

Aim. Study of efficacy and safety of taurin in management of stable angina patients with postinfarction cardiosclerosis.Material and methods. Totally, 95 postinfarction cardiosclerosis patients included, with stable angina of II and III functional class. The patients that were included, had refused revascularization. To the main group, 48 were included with added taurin (Dibicor, “PIK-Pharma”, Russia, 750 mg daily), and to comparison group — 47 patients that were taking standard treatment and placebo. Treatment duration 3 months. Results. Clinical efficacy of taurin in postinfarction cardiosclerosis and stable angina is confirmed by significant improvement of the following parameters: subjective state (decreased fatigue, less complaints on palpitation, less severity of dyspnea and rarer angina attacks), of the life quality parameters by Seattle questionnaire; echocardiographic parameters, normalized cardiac rhythm. Postive changes achieved on the basis therapy with taurin, remained for 3 months after drug discontinuation.Conclusion. Positive influence of taurin on clinical and instrumental parameters of patients make it to recommend its prescription for stable angina treatment in postinfarction cardiosclerosis patients.
Стиль исследователя – стиль исследования
Authors: Бондарская Галина  Алексеевна 
Published: May 2018

Рецензия на книгу А.Г. Волкова «Избранные демографические труды». Сборник научных статей. Составитель и научный редактор А. Г. Вишневский. М.: Издательский дом Высшей школы экономики, 2014, 568 стр.
The demographic revolution is changing the reproductive strategy of Homo sapiens
Authors: Vishnevsky Anatoly 
Published: May 2018

The demographic revolution (demographic transition) is changing the reproductive strategy of the species Homo sapiens. The whole evolution of life on Earth, including social evolution since the beginning of human society, has led to this triumph of theK-strategy of reproduction. This universal revolution has a crucial importance for the present stage of human history. The cause-and-effect relationship between economic, social and demographic changes is discussed, the interpretation of changes in the mass reproductive or family behavior as primarily a direct consequence of economic, social or cultural shifts is contested. Such explanations are redundant since the main changes in demographic behavior are a response to the necessity of restoring the demographic equilibrium upset by an unprecedented decline in mortality. At the same time, such explanations lead to an underestimation of the impact of demographic change on economic, social and cultural dimensions of the development of modern societies.
The demographic transition theory in its present form hinders the vision of this transition as an integral stand-alone process that has its own internal determinants and at the same time has a powerful impact on all social processes, including processes at the global level. The global logic of demographic transition theory is opposed to the widespread local logic, according to which this theory must be justified by the experience of each state.
An attempt is made to overcome the current fragmentation in the description of the demographic transition and its splitting into multiple “transitions” and “revolutions”, and to consider it as a cohesive process, that is, a sequence of inevitable major stages of a single global “chain reaction” initiated by an enormous decline in mortality.
Сословные различия в структурах домохозяйств в XIX веке: Москва и ее окрестности
Authors: Авдеев Александр  Александрович , Троицкая Ирина Алексеевна , Ульянова Галина Николаевна 
Published: May 2018

Последние десятилетия существенно изменили представления о типах структур домохозяйств на территориях, лежащих к востоку от линии Хайнала. Не только сама линия превратилась в достаточно обширную «переходную» зону, не только изменилось ее положение на карте Европы, но и разнообразие типов брака и семьи, обнаруженное за обобщенными характеристиками восточно- и центральноевропейских территорий, заставило исследователей пересмотреть некоторые теоретические концепции и результаты более ранних исследований. Такое расширение границ изучаемого явления стало возможным благодаря растущему числу микроисследований, предоставляющих детальную информацию о размере и составе домохозяйств в Центральной и Восточной Европе. Новые данные появились и для России, которая всегда считалась классическим примером «восточного» типа формирования семьи и организации домохозяйства.Тем не менее существующие исследования чаще принимают во внимание географическую, чем социальную/сословную стратификацию типов домохозяйств. Объектом подавляющего большинства исследований типов российских домохозяйств является социальная группа крепостных крестьян; другие сословия изучены гораздо менее детально.Мы постарались преодолеть этот разрыв, представив в данной статье сравнительный анализ структур домохозяйств в двух сословиях (московских купцов и подмосковных крепостных) в середине XIX века. Эти структуры существенно различались: в крестьянском населении преобладали сложные домохозяйства, состоящие из нескольких брачных пар (в середине XIX века их доля в общем числе домохозяйств доходила до 60%); у купцов, напротив, каждое второе домохозяйство было нуклеарным, состоящим из брачной пары с детьми или без, или одинокого родителя с детьми. Объяснения этому следует искать прежде всего в отношении обоих сословий к государственным повинностям.
Интегральные показатели демографических потерь от смертности и травматизма в результате дорожно-транспортных происшествий в России
Authors: Рамонов Александр  Владимирович 
Published: May 2018

В работе выполнен анализ динамики и структуры смертности и травматизма от дорожно-транспортных происшествий (ДТП) в России с 2006 по 2011 г., основанный на использовании интегральных показателей потерянных лет жизни. Показано, что максимальное число лет жизни, потерянных в результате смертности и травматизма (или выигранных в результате их устранения), среди мужчин приходится на возрастные группы от 40 до 65 лет, среди женщин – на промежуток от 55 до 75 лет.Применен новый метод оценки тяжести повреждений, наступивших в результате ДТП и других внешних причин.
Саймон Кузнец о демографических проблемах
Authors: Ткаченко Александр  Александрович 
Published: May 2018

В статье рассматриваются основные работы Саймона Кузнеца по вопросам взаимосвязи демографического и экономического роста. Отмечен особый вклад ученого в расширение показателей системы национальных счетов: включение ряда демографических показателей. Обращение американского экономиста к исследованиям народонаселения и его роли в экономической динамике в работе относится к более раннему периоду, чем это принято у ряда западных представителей истории экономической науки. Особое внимание уделено недостатку информации о нобелевском лауреате по экономике в России и незначительному числу переводов его фундаментальных работ на русский язык. Подчеркивается, что изучение творчества Кузнеца отечественными демографами поможет развитию фундаментальных экономико-демографических исследований в России.
Демографический дайджест
Authors: Кашницкий Илья Савельевич 
Published: May 2018

Murphy M. The Impact of Migration on Long-Term European Population Trends, 1850 to PresentKelle J., A.O. Haller. Who Benefits from Economic Growth? Work and Pay in BrazilVictora C.G., R. Bahl, A.J.D. Barros, G.V.A. França, S. Horton, J. Krasevec, S. Murch, M.J. Sankar, N. Walker, N.C Rollins. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect Stillwell J., M. Thomas. How far do internal migrants really move? Demonstrating a new method for the estimation of intra-zonal distanceMarjavaara R., E. Lundholm. Does Second-Home Ownership Trigger Migration in Later Life?Bell M., E. Charles-Edwards, P. Ueffing, J. Stillwell, M. Kupiszewski, D. Kupiszewska. Internal Migration and Development: Comparing Migration Intensities Around the WorldGoujon A., S. KC, M. Speringer, B. Barakat, M. Potancoková, J. Eder, E. Striessnig, R. Bauer, W. Lutz. A harmonized dataset on global educational attainment between 1970 and 2060 – an analytical window into recent trends and future prospects in human capital developmentCooray A., F. Schneider. Does corruption promote emigration? An empirical examinationUeffing P., F. Rowe, C.H. Mulder. Differences in Attitudes towards Immigration between Australia and Germany: The Role of Immigration Policy
Демографический дайджест
Authors: Кашницкий Илья Савельевич , Бирюкова Светлана Сергеевна 
Published: May 2018

Parr N., J. Li, L. Tickle. A cost of living longer: projections of the effects of prospective mortality improvement on economic support ratios for 14 advanced economies
(NCD-RisC), N. R. F. C. A century of trends in adult human height
Pal I., J. Waldfogel. The family gap in pay: new evidence for 1967 to 2013
Jakobsson N., A. Kotsadam. Does marriage affect men’s labor market outcomes? A European perspective
Gershoff E.T., A. Grogan-Kaylor. Spanking and child outcomes: old controversies and new meta-analyses
(NCD-RisC), N.R.F.C. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants
Fenge R., B. Scheubel. Pensions and fertility: back to the roots
Breschi M., G. Ruiu. Superstitions, religiosity and secularization: an analysis of the periodic oscillations of weddings in Italy
Demographic consequences of the Great Patriotic War
Authors: Vishnevsky Anatoly 
Published: May 2018

75 years have passed since the beginning of the Great Patriotic War, yet its demographic consequences, felt by Russia throughout all of this time, even now have not been completely overcome. Using general census data starting with the 1939 census, the article traces the fate of the generations who fought (those born between 1890-1926). It is shown that 82% of women and only 53% of men registered in the 1939 census survived until 1959. The resulting gender imbalance caused a sharp increase in the proportion of single women as a result of widowhood, and due to a shortage of suitors in the marriage market the share of non-marital births increased significantly. The war set in motion an oscillating cycle of the annual number of births which continues to this day. A relatively small number of deaths in the postwar decades, due to the fact that a huge number of people killed during the war did not live to a normal age of death, created the illusion of a safe balance of births and deaths in the 1970’s-1980's. Cyclical fluctuations in the size of generations induced by the war resulted in a wave-like dynamics of the working population and dependency ratio, complicating the functioning of the labor market and the implementation of economic and social programs, effects which are felt even in our day, for example, in the dynamics of pension contingents.
The author discusses the reasons for the huge military losses and suggests that if the war had not been preceded by erroneous decisions of the country’s political leaders, these losses could have been much smaller.
OSMANLI DÖNEMİNDE KELKİT VE ŞİRAN ÇEVRESİNDE YAŞANAN EŞKIYALIK OLAYLARI (1760-1916)
Authors: SAYLAN Kemal 
Published: May 2018

18. yüzyılın ikinci yarısından itibaren Osmanlı
Devleti’nin yıkılışına kadar geçen dönemde devletin ve toplumun içinde
bulunduğu muhtelif problemler Şiran ve Kelkit kazalarının çevresinde de kendini
hissettirmiştir. Bunun sonucu olarak zaman zaman bölgede eşkıyalık olayları
yaşanmıştır. Bu olayların yaşanmasının birçok sebebi vardır. Bölgedeki
eşkıyalık olaylarının ortaya çıkmasında Osmanlı Devleti’nin içinde bulunduğu
siyasi, askeri ve ekonomik durum, idari teşkilatlanmadaki değişiklikler, kolluk
kuvvetleri sayısının yetersizliği, bölge coğrafyasının eşkıyalık faaliyetlerine
müsait olması en önemli etkenler arasındadır.

Osmanlı Devleti,
bölgedeki eşkıyalık olaylarını engellemek için askeri, idari ve adli bazı
tedbirler almıştır. Ancak Osmanlı Devleti’nin yaşadığı olumsuz süreç alınan
tedbirlere rağmen belirtilen dönemde bölgedeki eşkıyalık olaylarının tamamen
ortadan kalmasını engellenmiştir. Bu çalışma; 1760-1916 yılları arasında Kelkit
ve Şiran çevresinde yaşanan eşkıyalık olayları ile bu olayların mahiyeti
hakkında bilgi vermeyi amaçlamaktadır.
GÜRCÜ SEYYAH GİORGİ ERİSTAVİ’NİN TRABZON VE İSTANBUL İZLENİMLERİ (1862)
Authors: NİKOLEİŞVİLİ Avtandil , ÇİMKE Harun 
Published: May 2018

Tarih boyunca stratejik konumundan
dolayı Türkiye, Gürcistan’ın Avrupa’ya açılan kapısı konumunda olmuştur.
Karayolunu tercih eden birçok Gürcü seyahatini Türkiye üzerinden yapmıştır.
Bunlar arasında meşhur Gürcü edebiyatçıları da vardır.Bu edebiyatçılardan birisi de Gürcü
Dramaturg ve Şair Giorgi Eristavi (1813-1864)’dir. Şair Eristavi “13 Haziran 1862’de Başlayan Avrupa
Seyahatim” adındaki eserinde denizyolu ile gerçekleştirdiği seyahati
sırasında uğradığı Trabzon ve İstanbul hakkında önemli bilgiler verir. XIX. yüzyıla ışık tutan bu bilgiler,
yalnızca Türkiye’nin içinde bulunduğu durumu yansıtmakla kalmayıp, aynı zamanda
tarihi süreci, gelenek ve göreneklerin bir yabancı seyyah tarafından
aktarılması açısından da önemli rol oynamaktadır. Bahsi geçen çalışmalarda yer
alan ve içerik bakımından Türkiye tarihine katkı sağlayacağını düşündüğümüz
bilgilerin Türkçeye çevrilmiş olmaması ve Türk okuyucu kitlesi tarafından
bilinmiyor olması Gürcistan-Türkiye ilişkileri açısından büyük bir eksiklik
olarak göze çarpmaktadır.

Bu çalışmada, Gürcü edebiyatçı Eristavi’nin Trabzon ve
İstanbul hakkındaki izlenimleri hakkında eserine dayalı olarak bilgiler
verilecektir.
Rapid Decompensation to Systemic Inflammatory Response Syndrome in Children with Osteomyelitis
Authors: Minkowitz Barbara , Ristic Jennifer R. , Murphy Lauren , Pierce Todd , Baorto Elizabeth 
Published: May 2018

Case:
We present 3 pediatric cases of osteomyelitis with delayed diagnosis, which resulted in systemic inflammatory response syndrome (SIRS) and complicated hospital stays.

Conclusion:
These 3 cases illustrate that early treatment of osteomyelitis is imperative in order to avoid fatal complications, which can occur with SIRS. Subtle signs and symptoms should not be dismissed. Patients with fever, pain, and no history of trauma should be scrutinized.
Heterotopic Ossification Formation Following a Simple Concussion
Authors: O’Callaghan Patrick K. , Carter Elliott , Walton Zeke , Chapin Russell , Bruner Evelyn 
Published: May 2018

Case:
A 19-year-old woman presented with a 3-month history of an enlarging lesion on the proximal aspect of the femur. After imaging studies and a biopsy had been performed, the mass was determined to represent heterotopic ossification (HO). The only known risk factor was a history of concussion. The mass was resected and, as of the 12-month follow-up, had not recurred.

Conclusion:
HO is a potentially serious complication of ossification in soft tissues that can develop secondary to several disease states; it commonly occurs following traumatic brain injury. To our knowledge, this is the only case report that describes HO associated with a concussion and no other risk factors.
An Evaluation of Maleic‐Itaconic Copolymers as Urease Inhibitors
Authors: Mazzei Luca , Broll Valquiria , Ciurli Stefano 
Published: May 2018

Core Ideas
Maleic‐Itaconic Polymers (MIPs) strongly and rapidly inactivate urease at pH 5.0.
MIPs favour the release of the essential Ni(II) ions from the active site of urease.
The urease inactivation by MIPs is comparable with that attained using NBPT.
Urea hydrolysis in soil is accelerated 1015–fold by the nickel‐dependent enzyme urease to yield a source of N that can be assimilated by plants. This reaction determines an overall soil pH increase and significant ammonia volatilization, decreasing the efficiency of urea‐based fertilization. A control of urease activity is thus required for agronomic purposes. Maleic‐Itaconic Polymers (MIPs) have been claimed to decrease the N loss as ammonia volatilization by inhibiting urease activity. To investigate this matter, we performed an in vitro study using urease from jack bean (Canavalia ensiformis, JBU) at pH 7.5 and pH 5.0. Urease is not affected by MIPs at pH 7.5, but the enzyme is completely inactivated in 20 min at pH 5.0 using MIPs in the 0.4 to 2.4 μmol L–1 range. This inactivation is comparable to that attained using similar concentrations of N‐(n‐butyl)‐thiophosphoric triamide (NBPT). In vivo assays conducted using Sporosarcina pasteurii as a model for a widespread soil bacterium and urea, in the presence of either MIPs or NBPT at pH 7.5, revealed that NBPT significantly inhibits both cellular growth and urease activity, while MIPs have no effect. To elucidate the mechanism of extracellular urease inactivation by MIPs in vitro, their Ni(II) sequestration capability was investigated. The MIPs (50 μmol L–1) completely extract the essential Ni(II) ions from the active site of urease at pH 5.0, in 3 h. This phenomenon is related to the capability of MIPs to shift the Ni(II)‐urease dissociation equilibrium through binding and chelation of the Ni(II) ions off the active site.