bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of Bragg gratings in planar hybrid metal–insulator–metal plasmonic waveguide using graded profile
Authors: Srivastava Kritarth , Chitimireddy Sindhura , Sharma Prateeksha , Vishwakarma Dinesh Kumar 
Published: June 2019

The design of integrated components using hybrid plasmonics is attracting a widespread interest in the recent years. This work proposes a consistent approach to design Bragg gratings employing the concept of graded profile in a planar hybrid metal–insulator–metal plasmonic waveguide. A comparative study of various width modulations such as triangular, parabolic and rectangular profiles is presented. The most striking observation is that Bragg gratings with parabolic profile offer best performance in terms of compact track length (3.48 μm), wide stopband (168 nm) and good transmission characteristics with fewer side lobes. Additionally, a nanocavity analysis is performed by introducing a defect length of 140 nm in the Bragg grating structure with parabolic profile. A peak transmission of 89% is observed at the resonance wavelength of 1550 nm.
Effects of22Ne sedimentation and metallicity on the local 40 pc white dwarf luminosity function
Authors: Tononi Jordi , Torres Santiago , García-Berro Enrique , Camisassa María E. , Althaus Leandro G. , Rebassa-Mansergas Alberto 
Published: June 2019

Aims. We analyzed the effect of the sedimentation of22Ne on the local white dwarf luminosity function by studying scenarios under different Galactic metallicity models.Methods. We use an advanced population synthesis code based on Monte Carlo techniques to derive the synthetic luminosity function. The code incorporates the most recent and reliable cooling sequences and an accurate modeling of the observational biases under different scenarios. We first analyzed the case for a model with constant solar metallicity and compared the models with and without22Ne sedimentation with the observed luminosity function for a pure thin-disk population. Then we analyzed the possible effects of a thick-disk contribution. We also studied model scenarios with different metallicities, including22Ne sedimentation. The analysis was quantified from a statisticalχ2-test value for the complete and also for the most significant regions of the white dwarf luminosity function. Finally, a best-fit model along with a disk age estimate was derived.Results. Models with constant solar metallicity cannot simultaneously reproduce the peak and cutoff of the white dwarf luminosity function. The additional release of energy due to22Ne sedimentation piles up more objects in brighter bins of the faint end of the luminosity function. The contribution of a single-burst thick-disk population increases the number of stars in the magnitude interval centered aroundMbol = 15.75. The metallicity model that follows a Twarog profile is disposable. Our best-fit model was obtained when a dispersion in metallicities of about solar metallicity was considered along with a22Ne sedimentation model, a thick-disk contribution, and an age of the thin disk of 8.8 ± 0.2 Gyr.Conclusions. Our population synthesis model is able to reproduce the local white dwarf luminosity function with a high degree of precision when a dispersion in metallicities around a model with solar values is adopted. Although the effects of22Ne sedimentation are only marginal and the contribution of a thick-disk population is minor, both of them help in better fitting the peak and the cutoff regions of the white dwarf luminosity function.
Blutung als Leitsymptom in der Notaufnahme
Authors: Schmid Bonaventura , Hodel Karin , Busch Hans-Jörg 
Published: June 2019

AbstractAcute bleeding is a common and challenging condition in the emergency room. The need for staff and medical resources in these patients depends on the clinical status and extent of the bleeding. The causes of acute bleeding are heterogeneous. Patients may appear in an emergency department with gastrointestinal, traumatic, intracerebral, gynecological or urological bleeding. Bleeding may be triggered or aggravated by underlying diseases or the use of anticoagulants or antiplatelet therapy. The treatment can range from general measures to complex intensive care with antidotes, blood coagulation and transfusion management. Nevertheless, the initial management in such cases is often the same.The purpose of this article is to give an overview of the different types of acute bleeding in an emergency room and how to overcome these specific challenges. Important is the initial management with appropriate general measures to stabilize the patient to avoid serious complications. It is helpful to set up structured processes for these cases.
Reactive Oxygen Species-Mediated Apoptosis and Cytotoxicity of Newly Synthesized Pyridazin-3-Ones In P815 (Murin Mastocytoma) Cell Line
Authors: Bouchmaa Najat , Mrid Reda Ben , Boukharsa Youness , Bouargalne Youssef , Nhiri Mohamed , Idir Abderrazak , Taoufik Jamal , Ansar Mʼhammed , Zyad Abdelmajid 
Published: June 2019

Abstract
Background In cancer cells, the intracellular antioxidant capacity and the redox homeostasis are mainly maintained by the glutathione- and thioredoxin-dependent systems which are considered as promising targets for anticancer drugs. Pyridazinones constitute an interesting source of heterocyclic compounds for drug discovery. The present investigation focused on studying the in-vitro antitumor activity of newly synthesized Pyridazin-3(2h)-ones derivatives against P815 (Murin mastocytoma) cell line.

Methods The in-vitro cytotoxic activities were investigated toward the P815 cell line using tetrazolium-based MTT assay. Lipid peroxidation and the specific activities of antioxidant enzymes were also determined.
Results The newly compounds had a selective dose-dependent cytotoxic effect without affecting normal cells (PBMCs). Apoptosis was further confirmed through the characteristic apoptotic morphological changes and DNA fragmentation. Two compounds (6f and 7h) were highly cytotoxic and were submitted to extend biological testing to determine the likely mechanisms of their cytotoxicity. Results showed that these molecules may induce cytotoxicity via disturbing the redox homeostasis. Importantly, the anticancer activity of 6f and 7h could be due to the intracellular reactive oxygen species hypergeneration through significant loss of glutathione reductase and thioredoxin reductase activities. This eventually leads to oxidative stress-mediated P815 cell apoptosis. Furthermore, the co-administration of 6f or 7h with Methotrexate exhibited a synergistic cytotoxic effect.
Conclusions considering their significant anticancer activity and chemosensitivity, 6f and 7h may improve the therapeutic efficacy of the current treatment for cancer.
Outcome Measures to Evaluate Upper and Lower Extremity: Which Scores are Valid?
Authors: Darwich Ali , Schüttler Viola , Obertacke Udo , Jawhar Ahmed 
Published: June 2019

Abstract
Objective In orthopaedics and trauma surgery scores are frequently used to assess treatment outcomes. The purpose of the review is to create an overview analysing the content of validity studies of frequently utilized scores for upper and lower extremity.
Methods Commonly used outcome measures to assess clinical outcome of upper (n = 19) and lower (n = 22) extremity were included. For each of the scores a comprehensive search in several databases (Medline, PubMed, google scholar) were performed to identify validation studies. The COSMIN-Checklist (COSMIN: Consensus-based Standards for the selection of health Measurement Instruments) introduced by Mokkink et al. were used to analyse systematically the methodological quality of the validation studies.
Results Validity, objectivity and reliability were not routinely considered and addressed in validation studies. The score related validation studies did not include all defined criteria of the COSMIN-Checklist. Six scores of the upper extremity and four scores of the lower extremity are not adequately validated. The best validated scores of the upper extremity is Oxford Shoulder Score (OSS) and for the lower extremity Hip Disabilities and Osteoarthritis Outcome Score (HOOS) as well as Western Ontario and McMaster Universities Score (WOMAC).
Conclusion There is no gold standard for the content-comprehension of validation studies due to the structure of the original study. The more criteria were tested the more informative and significant the outcome measure is. However some scores, such as Neer and Castaing Score, that lack validation are still being successfully used in research and clinical practice. The present review provides an overview of frequently used score in orthopaedics and trauma surgery and their grade of validity.
Continuous Beta-Blocker Therapy Delays Structural Deterioration after Bioprosthetic Mitral Valve Replacement
Authors: Ma Wenrui , Tan Yan , Shi Qiuxia , Xu Zhiwei 
Published: June 2019

AbstractThe impact of continuous beta-blocker (BB) therapy on structural valve deterioration (SVD) after bioprosthetic mitral replacement was investigated. From 2000 to 2005, 138 such patients were propensity score matched in a 1:1 fashion (continuous BB therapy after surgery, n = 69; without BB therapy, n = 69). Median follow-up was 12.3 years. Cardiac mortality was comparable between patients with and without BB therapy (p = 0.13), while the 10-year freedom from SVD was significantly higher in patients with BB therapy (92.4 vs. 76.3%, p = 0.001). In conclusion, continuous BB therapy may be considered in patients after bioprosthetic mitral valve replacement to delay SVD and improve prosthetic durability.
The Level of Mental Condition of South Slope Merapi Volcano Using Community Response Analysis
Authors: Sumunar D R S , Situmorang R M , Septiana M E 
Published: June 2019

AbstractMount Merapi’s activity in 2010 erupts VEI-4 which resulted in loss of life as much as 347 inhabitants, with most victims in the Regency of Sleman was 246 inhabitants. This problem causes of trauma in general slope of Merapi’s volcano. This research aims to know the impact of Merapi’s eruption on the mental condition of Merapi Community. This research uses qualitative research using the analysis of the percentage of public reponse questionnaire and indepth interviews of 42 respondents from 13 villages in the southern slope of Merapi’s Volcano about the mental condition of the southern slopes of Merapi’s volcano. The variables used in this research are the variable response of the community towards disaster preparedness, report of Merapi’s volcanic activity, experience, knowledge, and disaster response of the community. The results of this research are the community in Cangkringan Merapi Sub-district has a very bad mental condition, whereas in Pakem district experience a mental condition, and at sub-district of Turi have a very good mental condition. The community response rate is higher in Cangkringan sub-district because the eruption set into the Cangkringan Sub-district than other Sub-district in Sleman Regency. Community preparedness is very high, but the necessary trauma healing programs, especially in the area of Cangkringan Sub-district in order to minimize loss due to panic during the evacuation in the eruption.
Analysis and Prediction of Temperature Time Series Using Chaotic Approach
Authors: Bahari M , Hamid N Z A 
Published: June 2019

Abstract
Analysis and prediction of temperature time series is important because temperature changes can affect human’s health. The objectives of this study are to analyse and predict the temperature series in Jerantut, Pahang, Malaysia using chaotic approach. Modelling through chaotic approach divided into two stages; reconstruction of phase space and prediction processes. Through the reconstruction of phase space, a single scalar time series is rebuilt into a multi-dimensional phase space. This multi-dimensional phase space is used to detect the presence of chaotic dynamics through phase space plot and Cao method. The results show that the observed time series is chaotic in dynamic. Therefore, one hour ahead prediction through local mean approximation method is done. The correlation coefficient value obtained is 0.9789. The value which is approaching one reflected that the predicted time series and observed time series are close to each other. Thus, the modelling through chaotic approach is considered succeed. It is hoped that the model can help Malaysian Meteorological Department and Department of Environment Malaysia in order to improve their weather services.
Geoelectrical Prediction for Sliding Plane Layers of Rotational Landslide at the Volcanic Transitional Landscapes in Indonesia
Authors: Pratiwi E S , Sartohadi J , Wahyudi  
Published: June 2019

Abstract
The transitional between Quaternary and Tertiary volcanic landscapes is characterized by very deep interlayered clays. The the study of clay occurrence at certain depth through geophysical application is not intensively studied yet. Our sampling site is located at Bompon Sub-watershed where the rotational landslide are freqwently occurred. This research aims to investigate the characteristics of clay layer that potentially become sliding surface of landslides using two-dimensional (2D) resistivity method. Resistivity survey using dipole-dipole configration was conducted above three types of rotational slides typically occurred in the study area. We also did field observation as well as laboratory measurement for supporting data interpretation. Three kinds of interlayered clay materials are clearly detectable from 2D resistivity sections under all bodies of landslides. Those materials are entirely categorized as clay but different on cracks structure and cracks density, soil moisture, total porosity, bulk density, and specific gravity. Based on its physical characteristics, the saturated clay located around 10 up to 20 meters in depth is the most likely becoming sliding surface of landslides. This result is useful for understanding the nature of rotational slides commonly occurred in the volcanic transitional landscapes in Indonesia.
The Comparison of Stage and Result Processing of Photogrammetric Data Based on Online Cloud Processing
Authors: Ihsan M , Somantri L , Sugito N T , Himayah S , Affriani A R 
Published: June 2019

Abstract
The development of photogrammetric mapping with UAV mode has been generally used in recent years. One of the technologies development is Cloud-based data processing or using internet. There are two platforms providing facilities of cloud-based processing such as Pix4D and Drone Deploy. This research will be conduct comparison processing result of two platforms in terms of uploading process, total product and horizontal accuracy. The result showed that both platforms had each advantage. The result of Drone Deploy has advantage in term of more accurate coordinate, whereas PIX4D has advantage at completeness in processing reports.
Design and development of integrated savonius and darrieus small scale vertical axis wind turbine for power generation
Authors: Mojica Edison E , Fabay Cian Marvince , Kehinde Felix , Tenorio John Lambert 
Published: June 2019

Abstract
The study focuses on the integration of the darrieus and savonius wind turbine to a vertical axis wind turbine for power generation. The material used for darrieus was fiber glass with three blades and diameter of 350 mm, and polyvinyl chloride (PVC) for the savonius with four blades and diameter of 100 mm. The evaluation was conducted using a controlled wind source to vary its linear wind velocity. The actual power generated was compared to the theoretical power generated to identify the efficiency of the system. With the lowest linear wind velocity of 2.63 meters per second, the actual power output of the system (combination of the darrieus and savonius power output) was 3.79 watts and the theoretical power output is 6.03 watt. This made the system to be 62.85% efficient with low wind velocity. With the highest wind velocity of 12.52 meters per second, the output of the system was 408.80 watts and the theoretical output is 650.61 watts. This made the system to be 62.83% efficient. In an overall performance of the system with varying linear wind velocity, the efficiency of the system is close to 63%.
Determining Water Quality Status in University of Indonesia Depok Campus Lakes with STORET Method
Authors: Adi Haryo Kuntoro , Lestari Fatma , Kholis Noer , Abinawanto  , Abas Saleh , Bowolaksono Anom 
Published: June 2019

Abstract
The University of Indonesia has six artificial lakes around Depok Campus Area, namely Lake Kenanga, Agathis, Mahoni, Puspa, Ulin, and Salam (KAMPUS). These campus lakes have an area of about 17.5 hectares with an average depth varying between 1.5-3 meters with capability store waters up to 52,500 m3 of water. The University of Indonesia has its commitment to observe and evaluate the environmental quality as a part of an environmental monitoring program every semester. The observation data of lake water quality can provide information about parameters which has exceeded the environmental quality standard only, but not for the whole information about its water quality status. STORET Method is the common method which can be used to determine the water quality status. In principle, it compares the data of water quality measurement against national water quality standard appropriate with its purpose to determine the status of water quality. Based on the measurement data from 2017 to 2018, we obtained that Kenanga Lake, Agathis Lake, Ulin Lake, and Salam Lake has A Class quality status and meet the quality standard. However, Mahoni Lake and Puspa Lake are in C Class moderately polluted.
Detection of Pseudo Economic Growth Towards Environmental Damage in Indonesia Using Error Correction Model
Authors: Sumargo Bagus , Fadlilah Ema 
Published: June 2019

Abstract
Economic growth is one of the indicators of economic development. The effort to increase economic growth doesn’t pay attention to the environment be said the pseudo-economic growth. Using GDP per capita and CO2 emissions as indicators of economic growth and environmental damage, this study aims to examine the relationship between them using the Environmental Kuznets Curve (EKC) framework. The EKC hypothesis proposes a turning point at a certain level of economic growth so that sustainable development can be achieved. This study attempts to estimate EKC in the case of Indonesia for the period 1965-2014 by considering the role of fossil energy consumption. The method of analysis used the Error Correction Mechanism (ECM). The result showed that Indonesia is at the early stage of EKC. It indicates that an increase in economic growth leads to an increase of CO2 emissions and has not to reach a turning point. The type of fossil energy that has a positive and significant influence on CO2 emissions is oil.
Slope Stability Analysis for Landslides Natural Disaster Mitigation by Means of Geoelectrical Resistivity Data in Gedangan of South Malang, East Java, Indonesia
Authors: Sunaryo  , Susilo Adi , Yuwono Alamsyah M. , Wiyono  
Published: June 2019

Abstract
A study entitled slope stability analysis for landslides natural disaster mitigation by means of geoelectrical resistivity data in Gedangan of South Malang, East Java, Indonesia has been conducted. This study aims to obtain the physical parameters that cause landslides that occur in Gedangan village, Gedangan sub-district, Malang district. The research was conducted using geoelectrical resistivity method by applying a vertical electrical sounding (VES) model and Wenner-Schlumberger configuration. From the data as a result of field data acquisition, processing and interpretation are carried out to obtain landslide parameters. By merging each vertical electrical sounding (VES) point, physical parameters will be obtained as the basis for local landslide analysis. The results of the cross-sectional line A (GED4-GED1-GED2) indicate the presence of an average slope surface or topography that is relatively parallel with the average slope sliding plane which is about 7° whereas line B (GED1-GED3-GED5) is around 15°. The average thickness of the overlying layer in the slip plane both on line A and line B is around 65m. The slope condition of the slip plane (angle and thickness of the layer) indicates an unstable condition. For stable conditions F> = 1.2, the maximum thickness of the cover layer at line A is 54 m while in line B is 8.2 m. For stable conditions F> = 1.5, the maximum thickness of the cover layer for line A is 25.5 m while in line B is 5.85 m. To overcome the landslide, the proposed solution was by doing a reduction/dredging of the cover layer or installation of the bored piles.
Polymeric Inclusion Membrane (PIM) for Thiocyanate Extraction from Acid-Neutral Solution
Authors: Rumhayati Barlah , Mulyasuryani Ani , Wiryawan Adam 
Published: June 2019

Abstract
Thiocyanate can be found in the gold mine tailing that use cyanide method for gold extraction. Reaction of cyanide ion and sulphuric ion producing thiocyanate in the tailing which enhancing the environmental problem. A new polymeric inclusion membrane (PIM) has been developed to extract thiocyanate from acid to neutral solution. PIM was produced by diluting PVC as base polymer, trioctylamine (TOA) and tetraoctyl methyl ammonium chloride (TOMAC) as carriers, and 1-decanol as plasticizer in tetrahydrofurane (THF) as solvent. Thiocyanate concentration was measured based on the formation of Fe(III)-thiocyanate complex at 457 nm. As a result, thiocyanate could be extracted up to 42% using PIM technique with composition (w/w) 70% PVC, 15% TOMAC as carrier, and 15% 1-decanol as plasticizer. Feed phase was contained of 80 mg/L thiocyanate solution at pH 4. Stripping phase was contained of sodium chloride solution of 1.0 M
Sex and Body Mass Index Modify the Association Between Leptin and Sodium Excretion: A Cross-sectional Study in an African Population
Authors: Schwotzer Nora , Burnier Michel , Maillard Marc , Bovet Pascal , Paccaud Fred , Bochud Murielle , Wuerzner Grégoire 
Published: June 2019

Abstract

BACKGROUND
Renal sodium handling could be a potential mediator linking adipokines to hypertension. The aim of the study was to assess the relationship of leptin with urinary sodium excretion and proximal sodium reabsorption in humans.

METHODS
This cross-sectional study was conducted on participants of hypertensive families from the Seychelles Island. A split urine (daytime and nighttime) collection and plasma leptin were measured. Endogenous lithium clearance was used to assess proximal sodium reabsorption. Mixed multiple linear regression tests adjusted for confounding factors were used.

RESULTS
Three hundred and sixty-five participants (57% women) were included in this analysis. Leptin and adiponectin were higher in women (P &lt; 0.001). Leptin was associated positively with daytime (coefficient [c]: 0.16, standard deviation (SD): 0.03, P &lt; 0.001), nighttime urinary sodium excretion (c: 0.17, SD: 0.04), P &lt; 0.01), daytime lithium clearance (c: 0.40, SD: 0.08, P &lt; 0.001), and nighttime lithium clearance (c: 0.39, SD: 0.10, P &lt; 0.001) after adjusting for sex. The association was lost or mitigated only when BMI was introduced in the model. When BMI was categorized in normal vs. overweight participant, leptin was associated with daytime and nighttime sodium excretion rates (c: 0.14, SD: 0.05, P = 0.011 and c: 0.22, SD: 0.07, P = 0.002, respectively) only in overweight participants.

CONCLUSION
Leptin is associated positively with daytime and nighttime sodium excretion and lithium clearance suggesting a natriuretic rather than a sodium retaining effect of leptin. Sex and body mass index (BMI) are major confounders in this association. These results highlight the importance of sex and obesity in our understanding of the relationships between leptin, blood pressure, and renal sodium handling.