bluuebunny/crossref_metadata_2025_split huggingface dataset:
Indigenous knowledges, priorities and processes in qualitative organization and management research
Authors: Love Tyron Rakeiora 
Published: August 2019

Purpose
The purpose of this short paper is to comment on the powerful contribution researchers have made to the emerging field of Indigenous O&M scholarship.

Design/methodology/approach
The paper reviews the work in the field of Indigenous O&M.

Findings
Indigenous O&M research, first, has been driven by the effects of colonization and the attempts to reclaim traditional ways of researching, organizing and managing, second; has sought asylum in established critical and alternative fields of scholarship to create research legitimacy in the mainstream, and; third, produced novel methodological processes.

Originality/value
Several observations of the field will be made and some considerations are put forward to promote research within the tight – almost impenetrable – boundaries of the academy and its institutions.
Investigating unlearning and forgetting in organizations
Authors: Kluge Annette , Schüffler Arnulf Sebastian , Thim Christof , Haase Jennifer , Gronau Norbert 
Published: August 2019

PurposeInsight has grown that for an organization to learn and change successfully, forgetting and unlearning are required. The purpose of this paper is to summarize the relevant existing body of empirical research on forgetting and unlearning, to encourage research using a greater variety of methods and to contribute to a more complementary body of empirical work by using designs and instruments with a stronger reference to previous studies.Design/methodology/approachAs the number of theoretical papers clearly exceeds the number of empirical papers, the present paper deals with the main insights based on the empirical state of research on unlearning and forgetting. So far, these empirical results have shown relationships between unlearning and other organizational outcomes such as innovation on an organizational level, but many of the other proposed relationships have not been investigated. The authors presents suggestion to apply a larger variety of qualitative, quantitative and mixed methods in organizational research.FindingsUnlearning and forgetting research can benefit both from more diverse theoretical questions addressed in research and from a more complementary body of empirical work that applies methods, designs and instruments that refer to previous research designs and results. To understand and manage unlearning and forgetting, empirical work should relate to and expand upon previous empirical work to form a more coherent understanding of empirical results.Originality/valueThe paper presents a variety of research designs and methods that can be applied within the research context of understanding the nature of organizational forgetting and unlearning. Additionally, it illustrates the potential for different methods, such as experience sampling methods, which capture the temporal aspects of forgetting and unlearning.
Symbiosis of a P2‐family phage and deep‐sea Shewanella putrefaciens
Authors: Liu Xiaoxiao , Tang Kaihao , Zhang Dali , Li Yangmei , Liu Zhe , Yao Jianyun , Wood Thomas K. , Wang Xiaoxue 
Published: August 2019

SummaryAlmost all bacterial genomes harbour prophages, yet it remains unknown why prophages integrate into tRNA‐related genes. Approximately 1/3 of Shewanella isolates harbour a prophage at the tmRNA (ssrA) gene. Here, we discovered a P2‐family prophage integrated at the 3′‐end of ssrA in the deep‐sea bacterium S. putrefaciens. We found that ~0.1% of host cells are lysed to release P2 constitutively during host growth. P2 phage production is induced by a prophage‐encoded Rep protein and its excision is induced by the Cox protein. We also found that P2 genome excision leads to the disruption of wobble base pairing of SsrA due to site‐specific recombination, thus disrupting the trans‐translation function of SsrA. We further demonstrated that P2 excision greatly hinders growth in seawater medium and inhibits biofilm formation. Complementation with a functional SsrA in the P2‐excised strain completely restores the growth defects in seawater medium and partially restores biofilm formation. Additionally, we found that products of the P2 genes also increase biofilm formation. Taken together, this study illustrates a symbiotic relationship between P2 and its marine host, thus providing multiple benefits for both sides when a phage is integrated but suffers from reduced fitness when the prophage is excised.
Confronting Bluebeard: totalitarian regimes in childhood and in the collective psyche
Authors: Wright Susanna 
Published: August 2019

AbstractBeginning with the story of Bluebeard, the author considers how traumatic overwhelm can occur in everyday childhood situations of a psychically murderous quality; for example, a nanny’s totalitarian regime may be invisible to parents ruled by collective social and cultural norms. A child who is remote from mother and idealises a father embodying a powerful patriarchal system may remain naïvely dependent in marriage and unable to cope with the realities of human aggression. The paper describes analytic work with a woman who had suffered repeated breakdowns and needed to relinquish a fragile, socially constructed identity in order to establish her own true orientation.
When culture fails: coping with cultural trauma
Authors: Gailienė Danutė 
Published: August 2019

AbstractThe research into the phenomenon of cultural trauma is growing as the effects of historical transformations are recognized and analysed. The concept of cultural trauma and the analytic concept of the cultural complex is a suitable theoretical approach for this research. The Lithuanian experience of cultural trauma after the historical shifts indicates the importance of the interplay between societal and individual factors in coping with trauma. Academic psychotraumatological studies carried out at Vilnius University indicate a stronger traumatic experience by people who are survivors of direct political repression and even intergenerational transmission of trauma, but this group also seems to demonstrate an intergenerational transmission of resilience. Paradoxically, from a long‐term perspective, the victims of direct repression seem to have suffered less than the people who accommodated to the regime, and this applies also to their offspring. Analysis in terms of overcoming cultural trauma indicates that society is gradually integrating historic traumatic experiences, although a healthy cultural identity has not yet been restored.
Disquiet in the consulting room: everything/nothing that is said here is confidential
Authors: Meyerowitz‐Katz Julia 
Published: August 2019

AbstractWriting from experiences in the consulting room in private practice in Australia, the author refers to the layered complexity of a conflict of ethical duty which has legal and social implications. The paper explores how the ethics that are congruent with creating a safe vas bene claustrum can be diametrically opposed to the social and legal structures and processes on which we all rely. It is suggested that within the vas, analysts and analysands engage in a shared process of emotionally connected, layered, symbolic thinking. Subpoenas directed at analysts are seeking concrete evidence that will stand up in court. The paper argues that this is a category error based on ignorance and misconceptions of what analytic work entails. The intrusion of a subpoena into the vas has the potential to cause havoc in the mental health and the lives of already vulnerable, possibly traumatized and isolated individuals. It can undermine a fundamental human right and undermine the profession of psychotherapy as a whole. The paper proposes that analysts have an ethical obligation to protect the work contained within the vas from these category errors and to educate other professionals as to why we cannot provide the kind of evidence that the courts require.
Trauma, resilience and healthy and unhealthy forms of dissociation
Authors: Alayarian Aida 
Published: August 2019

AbstractThis paper outlines the difference between healthy and unhealthy forms of dissociation following, and in response to, traumatic experience, in particular the experience of refugees, calling on 30 years’ experience in working with refugees in voluntary and public sectors, including 20 years at the Refugee Therapy Centre, London. It differentiates dissociation from repression, and looks at some of the specific traumatic experiences associated with refugees’ displacement and situation, particularly relating to loss. Four key characteristics of resilience are described: ‘psychic space’, ‘sense of self’, and the use of a ‘listening other’ and ‘healthy dissociation/resiliency’. Two vignettes are given to illustrate the difference between healthy and unhealthy dissociation.
Sustainability Northwest: An Integrative Case of a Not‐for‐Profit Organization
Authors: Lento Camillo , Lento Paolo , Pratola Angela 
Published: August 2019

AbstractSustainability Northwest (SNW) is a fictional not‐for‐profit organization (NPO) that seeks to develop thought leaders for a sustainable future. This instructional case allows professors to assign students with up to six different roles, including SNW's chair of the board, executive director, volunteer treasurer, and the external auditor. Unique learning objectives include (i) the application of the CPA Canada Handbook, Accounting—Part III to prepare an NPO's financial statements using fund accounting, (ii) the development of recommendations to improve an NPO's board of directors, (iii) the analysis of system flow documents to identify control weaknesses, and (iv) the preparation of an audit planning memo. Instructors can use this case in several milieus. First, professors can foster a student's ability to integrate technical knowledge by (i) assigning students all six roles in a capstone course to promote integration within an individual course or (ii) assigning multiple roles across multiple courses to promote integration across a program of studies. Second, instructors can focus on a particular technical skill by assigning specific roles. This case is ideal for senior‐level undergraduate students or graduate students.
Cerebellar parcellation in schizophrenia and bipolar disorder
Authors: Laidi C. , Hajek T. , Spaniel F. , Kolenic M. , d'Albis M.‐A. , Sarrazin S. , Mangin J.‐F. , Duchesnay E. , Brambilla P. , Wessa M. , Linke J. , Polosan M. , Favre P. , Versace A. L. , Phillips M. L. , Manjon J. V. , Romero J. E. , Hozer F. , Leboyer M. , Coupe P. , Houenou J. 
Published: August 2019

ObjectiveThe cerebellum is involved in cognitive processing and emotion control. Cerebellar alterations could explain symptoms of schizophrenia spectrum disorder (SZ) and bipolar disorder (BD). In addition, literature suggests that lithium might influence cerebellar anatomy. Our aim was to study cerebellar anatomy in SZ and BD, and investigate the effect of lithium.MethodsParticipants from 7 centers worldwide underwent a 3T MRI. We included 182 patients with SZ, 144 patients with BD, and 322 controls. We automatically segmented the cerebellum using the CERES pipeline. All outputs were visually inspected.ResultsPatients with SZ showed a smaller global cerebellar gray matter volume compared to controls, with most of the changes located to the cognitive part of the cerebellum (Crus II and lobule VIIb). This decrease was present in the subgroup of patients with recent‐onset SZ. We did not find any alterations in the cerebellum in patients with BD. However, patients medicated with lithium had a larger size of the anterior cerebellum, compared to patients not treated with lithium.ConclusionOur multicenter study supports a distinct pattern of cerebellar alterations in SZ and BD.
Effect of changes in population density and crop productivity on farm households in Malawi
Authors: Komarek Adam M. , Msangi Siwa 
Published: August 2019

AbstractThis study examines the ex‐ante farm‐household effects of changes in family size, yield potential, and yield gaps using a farm‐household simulation model that reflects the economic and biophysical conditions of central Malawi. Disparities between growth in human population and crop yields present challenges for farm‐household crop production and income in sub‐Saharan Africa. We focus on the effect of growth in yield potential and a more efficient use of livestock manure as approaches to improving crop production and incomes in the face of looming population pressures. Our results suggest that, even without considering climate change, expected changes in population density and crop prices in 2050 mean that per person crop production and income may fall by 21% compared to 2013 values if yield potential and yield gaps remain constant. However, per person crop production and income could increase in 2050 by 8% compared to 2013 values if (1) growth rates of yield potential rise for maize by 1.13% each year and for legumes rise by at least 0.4% each year, and (2) farmers use livestock manure more efficiently. Our foresight approach to considering crop production at the farm‐household scale supplements macro‐scale analyses of the production dimension of food security.
Is public investment complementary to private investment in Indian agriculture? Evidence from NARDL approach
Authors: Akber Nusrat , Paltasingh Kirtti Ranjan 
Published: August 2019

AbstractThe issue of complementarity between public farm investment and private farm investment in Indian agriculture is an unsettled empirical question in the literature, which has not been studied adequately. Few studies analyzing the trends of both types of investments have produced contradictory results. Thus, this study attempts to bridge that gap, by examining the hypothesis of crowding‐in/crowding‐out effect of public sector investment on private investment. Time series data for a period of 45 years from 1971 to 2015 has been used. Adopting a ‘nonlinear auto‐regressive distributive lag’ (NARDL) model the study confirms a strong crowding‐in effect of public investment on private investment in short run, but relatively a weak complementarity between the two over long‐run. Moreover, the public canal intensity as a major component of public investment has been observed to have much stronger effect on private investment than the public investment itself. It is also found that private investment is constrained by its own lagged values, institutional credit and terms of trade during both short‐run and long‐run. The policy suggestion of this study calls for an immediate arrest of declining trend of public investment.
Editorial: real‐world short‐term effectiveness of ustekinumab in 305 patients with Crohn’s disease—results from the ENEIDA registry. Authors' reply
Authors: Iborra Marisa , Beltrán Belén , Nos Pilar 
Published: August 2019

LINKED CONTENT
This article is linked to Iborra et al and Frasca and Cheifetz papers. To view these articles, visit https://doi.org/10.1111/apt.15371 and https://doi.org/10.1111/apt.15405.
Sex, age, or genetic differences related to play behaviors in Japanese Black calves
Authors: Aierqing Sarengaowa , Nakagawa Akiko , Okita Miki , Bungo Takashi 
Published: August 2019

AbstractPlay behavior in young animals has been used to evaluate the condition (health) of livestock. We investigated age, sex, and genetic differences of Japanese Black calves in relation to frequency of play behaviors (galloping, leaping, turning, bucking, head butting objects, and head shaking) and examined how these relationships might affect growth during the suckling stage. Locomotor play behaviors (galloping, leaping, turning, and bucking) and head butting objects gradually declined with the age for both sexes. The frequency of head butting was significantly higher in males than females. We found that significant interaction effects (age × MAOA polymorphism) in play behaviors (except head shaking) and the frequencies of locomotor play in calves without the wild‐type allele were significantly higher than those in younger calves (2 and 6 weeks of age). Weight gain was significantly correlated with the frequency of locomotor play in females, but not in males. This study suggests that play in Japanese Black calves gradually declines as they mature and that play may be controlled by variations in the MAOA gene. In addition, the frequency of locomotor play may be an indicator of health in female calves.
A pilot study of Australian pet owners who engage in social media and their use, experience and views of online pet health information
Authors: Kogan LR , Hazel SJ , Oxley JA 
Published: August 2019

ObjectiveThe aim of this study was to gain a better understanding of Australian pet owners' use of the internet for pet health; how trustworthy they rate various pet health information sources and the use of online information in subsequent veterinary consultations.MethodAn anonymous questionnaire was developed, consisting of 30 questions, and distributed between March 2018 and May 2018 using convenience sampling through social media venues including Facebook and Twitter. All respondents were over the age of 18, lived in Australia and owned a pet animal.ResultsA total of 228 responses were received. The most common sources of pet health information were veterinarians (88.2%) and internet websites (81.1%). Most respondents reported using the internet ‘many times per day’ at either home or work. The majority of respondents used the internet to seek pet health information either ‘not weekly but at least once a month’ or ‘less than once a month’. Nearly half of the respondents stated that they only ‘sometimes’ discuss their online findings with their veterinarian. Approximately one half of respondents agreed with the statement that online pet health information had affected their decision about whether to take their pet to the veterinarian.ConclusionThis study assesses how pet owners use the internet for pet health information and the role veterinarians can play in helping to facilitate these searches with tools such as information prescriptions. Further large‐scale research is needed to help further understand this increasingly important aspect of pet health.
Byssus production ability and degree of byssal‐gland development in the infaunal clam Ruditapes philippinarum
Authors: Takeuchi Seiji , Honma Kohei , Hirasaka Katsuya 
Published: August 2019

AbstractByssus production of Ruditapes philippinarum clams becomes reduced with growth. This tendency is well recognized but has not been analysed in detail. Additionally, it remains uninvestigated whether the lack of competence to produce byssus threads in the adult stage is caused by atrophy of the byssal glands or not. The objective of this study was to evaluate the byssus production ability of clams through the juvenile to adult stages and to examine the importance of two endogenous factors (i.e. shell size, somatic condition) in determining the byssus production probability (proportion of clams with byssus production in a population). This study also histologically confirmed the presence of byssal glands in juvenile to adult clams. For these purposes, field surveys to investigate the relationship among byssus production, shell size and somatic condition of clams collected from four intertidal sites and a histological study for byssal glands of the clams was conducted. This study revealed that byssus production probability decreases with increasing shell size and declining somatic condition and that the lack of byssus production is not caused by the loss of the byssal glands.
Population pharmacokinetic modelling and simulation of fremanezumab in healthy subjects and patients with migraine
Authors: Fiedler‐Kelly Jill B. , Cohen‐Barak Orit , Morris Denise N. , Ludwig Elizabeth , Rasamoelisolo Michele , Shen Honglue , Levi Micha 
Published: August 2019

AimsFremanezumab is a fully humanized IgG2Δa/κ monoclonal antibody specific for calcitonin gene‐related peptide developed and approved for the preventive treatment of migraine in adults. The population pharmacokinetics (PK) of fremanezumab were characterized in healthy subjects and patients with chronic migraine and episodic migraine, including the effects of intrinsic and extrinsic factors on PK variability.MethodsNonlinear mixed effects modelling was performed using NONMEM with data from 7 phase 1–3 clinical trials evaluating selected intravenous and subcutaneous dose regimens. The influence of covariates on fremanezumab PK was assessed and model evaluation was performed through visual predictive checks.ResultsA 2‐compartment model with first‐order absorption and elimination described the PK data well. Typical values for fremanezumab central clearance (0.0902 L/d) and central distribution volume (1.88 L) for a 71‐kg subject were consistent with previously reported values for IgG antibodies. Higher body weight was associated with increased central clearance and distribution volume. Effects of other covariates (age, albumin, renal function, sex, race, injection site, and acute, analgesic and preventive medication use for migraine) were not found to statistically significantly influence fremanezumab PK. There was no indication of reduced exposure in participants with positive anti‐drug antibody status or with mild to moderate hepatic impairment. Absolute bioavailability was estimated at 0.658.ConclusionsA comprehensive population PK model was developed for fremanezumab following intravenous and subcutaneous administration in healthy subjects and patients with chronic migraine or episodic migraine, which will be used to further evaluate exposure–response relationships for efficacy and safety endpoints.
GDF11 contributes to hepatic hepcidin (HAMP) inhibition through SMURF1‐mediated BMP‐SMAD signalling suppression
Authors: Fang Zheng , Zhu Zesen , Zhang Haihang , Peng Yuanliang , Liu Jin , Lu Hongyu , Li Jiang , Liang Long , Xia Shenghua , Wang Qiguang , Fu Bin , Wu Kunlu , Zhang Lingqiang , Ginzburg Yelena , Liu Jing , Chen Huiyong 
Published: August 2019

SummaryHepcidin (HAMP) synthesis is suppressed by erythropoiesis to increase iron availability for red blood cell production. This effect is thought to result from factors secreted by erythroid precursors. Growth differentiation factor 11 (GDF11) expression was recently shown to increase in erythroid cells of β‐thalassaemia, and decrease with improvement in anaemia. Whether GDF11 regulates hepatic HAMP production has never been experimentally studied. Here, we explore GDF11 function during erythropoiesis‐triggered HAMP suppression. Our results confirm that exogenous erythropoietin significantly increases Gdf11 as well as Erfe (erythroferrone) expression, and Gdf11 is also increased, albeit at a lower degree than Erfe, in phlebotomized wild type and β‐thalassaemic mice. GDF11 is expressed predominantly in erythroid burst forming unit‐ and erythroid colony‐forming unit‐ cells during erythropoiesis. Exogeneous GDF11 administration results in HAMP suppression in vivo and in vitro. Furthermore, exogenous GDF11 decreases BMP‐SMAD signalling, enhances SMAD ubiquitin regulatory factor 1 (SMURF1) expression and induces ERK1/2 (MAPK3/1) signalling. ERK1/2 signalling activation is required for GDF11 or SMURF1‐mediated suppression in BMP‐SMAD signalling and HAMP expression. This research newly characterizes GDF11 in erythropoiesis‐mediated HAMP suppression, in addition to ERFE.