bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stress-induced arterial hypertension: search for predictors
Authors: Ambatiello L. G. , Bravaya A. I. , Rogoza A. N. , Chazova I. E. 
Published: October 2024

Background. Despite the existence of a clear cause-and-effect relationship between job strain and hypertension, there are still no clear criteria for defining stress-induced arterial hypertension (SIAH). Objective. Search for SIAH criteria, in particular predictors of hypertension in the workplace. Materials and methods. The study included volunteers experiencing stress in the workplace and not having hypertension. Before the start of the working day and at the end of the working day, the subject was surveyed, given questionnaires (Ch. D. Spielberg scale, Montgomery-Asberg MADRS scale, A. M. Vein scale, hospital anxiety and depression scale HADS), blood pressure and resting heart rate were measured, fasting blood was taken to determine the values of ACTH, TSH, T4, insulin, cortisol. All patients underwent ABPM on a working day and a day off. Results. According to ABPM (n=52), no signs of masked hypertension were detected, however, significant differences between workdays and weekends in the levels of maximum SBP and DBP during the daytime were noteworthy. In the group with maximum SBP>140 mm Hg during the daytime (SIAH, n = 34), on a workday there was an increase in the time index for SBP>30% (24 hours and day), characteristic of hypertension, and for DBP (24 hours and day), characteristic of borderline (possible) hypertension, the average DBP values during the day and at night were at the upper limit of the norm, which was significantly different from the Normotonic group (n = 19). On a weekday, the SIAH group also had significantly increased SBP (24 hours, day) and DBP (24 hours, day and night) indexes versus Normotonic. For all other indicators except ABPM, the groups were comparable. Conclusions. Taking into account the increase in the time index for SBP and DBP, it can be assumed that, against the background of stressful situations at the workplace, the subjects had short frequent increases in blood pressure, which have not yet led to a significant violation of self-regulation of blood pressure and the development of hypertension. An increase in the maximum values of systolic and/or diastolic blood pressure against the background of an increased time index on a working day are possible predictors of SIAH, in particular hypertension at the workplace.
Chronopharmacotherapy and correction of central pressure in the aorta, structural and functional state of the left ventricular in patients with arterial hypertension and ischemic stroke
Authors: Skibitsky V. V. , Fendrikova A. V. , Kalinina S. V. , Zabolotskyh T. B. 
Published: October 2024

Objective. To evaluate the dynamics of central aortic pressure and the cardioprotective effect of antihypertensive chronopharmacotherapy in patients with arterial hypertension (AH) and ischemic stroke. Materials and methods. The study included 119 patients with AH who has suffered an ischemic stroke; patients were randomized in 2 groups depending on the chronopharmacotherapy option: group 1 (n = 60) – patients who received indapamide retard 1.5 mg and valsartan 160 mg in the morning; group 2 (n = 59) – indapamide retard 1.5 mg in the morning and valsartan 80 mg each in the morning and before bedtime. After 2 months of pharmacotherapy, the achievement of the target level of blood pressure was assessed. In group 1, blood pressure was recorded in 47 (78.3 %), in group 2 – in 56 (94.9 %) patients (p < 0.05). The rest of the respondents, who did not reach the blood pressure target, underwent correction of antihypertensive therapy and were excluded from further follow-up. Accordingly, further follow-up was carried out in 47 patients of group 1 (group 1a) and 56 patients of group 2 (group 2a). Initially and after 12 months of therapy, echocardiography parameters ("ALOKA SSD 2500", Japan), as well as daily blood pressure monitoring with determination of central aortic pressure (Peter Telegin LLC BPLabVasotens, Russia) were performed. The results of the study were processed using the Statistica 12.0 program (StatSoftInc, USA). Results. At the time of inclusion in the study, the main parameters of the central aortic pressure and echocardiography parameters in both groups of patients were equivalent. After 12 months a statistically more significant decrease in the main parameters of the central aortic pressure (average daily systolic and diastolic pressure in the aorta, pulse pressure in the aorta, augmentation index in the aorta, amplification of pulse pressure, duration of the expulsion period, subendocardial blood flow efficiency index), as well as echocardiography indicators was recorded in group 2a (end-systolic and end-diastolic dimensions, thickness of the interventricular septum, thickness of the posterior wall of the left ventricular myocardium, left ventricular myocardial mass, left ventricular myocardial mass index and ejection fraction) (p < 0.05). The left ventricular myocardial geometry normalized during therapy was recorded significantly more often in group 2a than in group 1a (p < 0.05). Conclusion. Two times a day intake of valsartan with thiazidelike diuretic in the morning facilitated more significant improvement of central aortic pressure, echocardiography parameters and as well as an improvement in the geometry of the left ventricular myocardium comparing to just morning intake.
Impact of a new coronavirus infection on the level of inflammatory, haemostasis markers and microcirculatory parameters of patients with arterial hypertension
Authors: Kokaeva I. O. , Zhernakova Yu. V. , Blinova N. V. 
Published: October 2024

Relevance. The COVID-19 pandemic and its consequences have significantly affected the health of the population as a whole. Persons who have undergone coronavirus infection against the background of chronic cardiovascular diseases and obesity deserve special attention. Aim. To study and compare the main indicators of carbohydrate and lipid metabolism the level of inflammatory and haemostasis markers, microvascular changes in obesity AH patients and in AH patients with normal body weight 1 month after a new coronavirus infection in moderate to severe form. Materials and methods. The study included 87 patients of both sexes, aged from 18 to 55 years, from which three groups were formed: the first group included people with AH and normal body weight (BMI<25 kg/m²) who had undergone COVID-19 within a month, the second group included people with AH and obesity (BMI≥30 kg/m²) who had undergone COVID-19 within a month, the control group consisted of 20 people with AH and obesity without COVID-19. The parameters of height, weight, waist circumference, and BMI were assessed in all subjects. The parameters of lipid profile, glucose level were determined, inflammatory markers and haemostasis parameters. All participants underwent laser Doppler flowmetry (LDF) on the forearm with constrictor and dilator functional tests, and single-photon emission computed tomography (SPECT) in combination with x-ray computed tomography (SPECT/CT). Results. Patients of groups 1 and 2 naturally differed from each other in anthropometric indicators. Lipid and carbohydrate metabolism rates were also significantly higher in group 2 patients compared to group 1 patients (p < 0.05). The CRP level in the group of people with hypertension and obesity who underwent COVID-19 was significantly higher than in people with hypertension without obesity (p < 0.001) and than in people with hypertension and obesity without a history of COVID-19. When comparing microcirculation parameters by LDF, there was a decrease in tissue hemoperfusion (M), blood flow reserve (RK) in all three groups (p < 0.001), the most pronounced dysfunction of neurogenic and myogenic blood flow regulation was detected in the group of people with hypertension andobesity who underwent COVID-19. Conclusion. The study of microcirculation indicators by LDF method in persons with hypertension and obesity after suffering a coronavirus infection indicates the predominance of the spastic type of microcirculation, which, together with an increase in the levels of inflammatory markers, indicates a higher risk of thrombosis and cardiovascular complications, requiring more careful monitoring and treatment of this group of patients.
Inter-rater and Intra-rater Reliability of Het’s MMT in Pelvic Floor Assessment
Authors: Agnihotri Dhara Santosh , Bhise Anjali Ravindra , Mahishale Arati Vinay , Saini Vandana K. , Amersheda Shila Bhagwanji , Mange Yojana Navneet , Gupta Samiksha , Bhojani Ushma , Biswas Garima 
Published: October 2024

Objective:
Pelvic floor dysfunctions (pfds) such as urinary incontinence, pelvic organ prolapse, and vaginismus are very common and are affecting the quality of life of the female suffering through it. The pelvic floor muscles can be in spasm, thus resulting in the inability to relax or the pelvic floor muscles can be extremely weak or loose, resulting in the inability to contract strongly and completely. The spasmodic pelvic floor can result in vaginismus, dyspareunia, chronic pelvic pain, constipation, etc., Moreover, a weak pelvic floor can lead to issues such as urinary incontinence, pelvic organ prolapse, and sexual dysfunction. There is a scarcity of a valid and reliable scale that assesses both the components of pfd.

Subjects and Methods:
The present study was conducted on 1349 participants which were divided into three groups on the basis of their symptoms. Group A – No symptoms (n = 439), Group B – Hypotonus pfd (n = 658), and Group C – Hypertonus pfd (n = 252). Examination: Vaginal examination to assess the pelvic floor muscles relaxation and contraction was done by Het’s Manual Muscle Testing (MMT). Inter rater reliability was assessed by comparing the data of two independent examiners on the same day. The intra rater reliability was assessed by comparing the data of test and retest at an interval of 1 week.

Results:
The intra rater reliability at 95% confidence interval (CI) was 0.92 – Normal pelvic floor function, 0.96 – Hypotonus pfd, and 0.97 – Hypertonus pfd. Moreover, inter rater reliability at 95% CI was 0.93 – normal pelvic floor function, 0.95 for hypotonus pfd, and 0.98 – hypertonus pfd.

Conclusions:
This study concludes Het’s MMT is a highly reliable manual muscle testing tool to assess the pelvic floor muscles.
A Cross-sectional Survey to Assess the Risk Factors of Cardiovascular Disease among College Students
Authors: Ali K. Jafar , Suthar Hansaram 
Published: October 2024

Introduction:
Cardiovascular diseases (CVDs) are the number one cause of death globally which claim an estimated 17.9 million lives each year. It is a major cause of disability and premature death throughout the world and contributes substantially to the escalating costs of health care. Modification of risk factors has been shown to reduce mortality and morbidity in people with diagnosed or undiagnosed CVDs. Prior assessment is found to be helpful in predictions of absolute cardiovascular risks among young adults.

Objectives:
The objective of the study was to assess the risk factors of cardiovascular diseases among college students.

Materials and Methods:
A descriptive survey was conducted among 207 college students at Najath College of Science and Technology, Karuvarakundu, Kerala from October 10, 2019, to October 18, 2019. Convenient sampling method was used to select the samples. Structured risk factor assessment Pro forma and Biophysical measurements were used as tools.

Result:
The study identified 40.57% of students as at moderate risk and 5.31% were at high risk for developing cardiovascular diseases. The study reported that 6.2% of students were overweight, whereas 45% had elevated blood pressure. It was found that 64.25% of the students had a family history of chronic illnesses such as diabetes, hypertension, stroke, and obesity. The 8.21% of students were smokers out of these, 17.39% were using smokeless tobacco, whereas 31.88% were exposed to passive smoking and 12.56% of students were drinkers. In terms of physical activity, 62.31% of the students were sedentary. The food habits of 98.56% of students were nonvegetarian and 46.85% of them were consuming red meat.

Conclusions:
Periodic assessment and comprehensive health awareness would be helpful to modify unhealthy habits and minimize the risk of cardiovascular problems among the college students.
Donor Parameters and Platelet Yield during Plateletpheresis: A Cross-sectional Prospective Study
Authors: Singh Ruchi , Pilli Ganga S. , Wani Ramadevi Vivek 
Published: October 2024

Background:
Platelet transfusion can be life-saving in bleeding patients with thrombocytopenia or reduced platelet function. Single donor platelets (SDP) unit use is preferred due to the various advantages like reduction in transfusion-transmitted diseases and transfusion reactions. The quality of SDP is determined by platelet yield. Therefore, we conducted this study to assess the donor parameters affecting platelet yield during plateletpheresis.

Materials and Methods:
This cross-sectional prospective study included 160 single-donor platelet apheresis procedures done for 1 year. The pre-donation platelet count of the donor was set to 250 × 109/L to get double-dose platelet. Plateletpheresis was performed using Trima Accel single-needle separator apheresis machine. The demographic and hematologic parameters of donors were correlated with their platelet yield. Data obtained were tabulated using version 20 of the Statistical Package for the Social Sciences (SPSS). A relationship between pre-donation donor variables and platelet yield was studied using the Pearson correlation coefficient (r). P < 0.05 was considered statistically significant.

Results:
There was a significant positive correlation between platelet yield and body mass index (BMI) (r = 1710 and P = 0.0304), total leukocyte count (TLC) (r = 0.2220 and P = 0.0048), and platelet count (r = 0.8880 and P < 0.0001). The mean platelet volume (MPV) showed a negative correlation with platelet yield (r = −0.1910 and P = 0.0156). Age, hemoglobin, hematocrit, and platelet distribution width showed no significant correlation with the platelet yield.

Conclusion:
Donor parameters such as pre-donation platelet count, BMI, TLC, and MPV need to be considered while recruiting the donors for the SDP procedure for better yield of platelets.
Analysis of Clinical and Laboratory Profiles of Patients Hospitalized with Hemorrhagic Fever with Renal Syndrome in Southwestern South Korea
Authors: Park Ma Eum , Kim Da Young , Seo Jun-Won , Yun Na Ra , Lee You Mi , Kim Choon Mee , Kim Dong-Min 
Published: October 2024

ABSTRACT.
Hemorrhagic fever with renal syndrome (HFRS) is caused by hantaviruses. Data of 34 patients with HFRS hospitalized at Chosun University Hospital, South Korea, between 2010 and 2021 were retrospectively analyzed. Nested reverse transcription polymerase chain reaction (RT-nPCR) targeting the L segment of hantavirus and sequencing were used for diagnosis. Most cases occurred in men and during the months of October through December. Common symptoms were fever, chills, gastrointestinal symptoms, and myalgia. The common laboratory abnormalities were thrombocytopenia, proteinuria, and elevated levels of serum creatinine, aspartate transaminase, alanine transaminase, and lactate dehydrogenase. Approximately 91.2% of patients had the Hantaan virus with a new genotype cluster, whereas 8.8% had the Seoul virus. Seropositivity based on IgM titer >1:32 on admission was noted in 20.6%, and a 4-fold increase in IgG titer of 1:512 was observed in 11.8%. This study demonstrated that RT-nPCR targeting the L segment of hantaviruses is a more reliable diagnostic method compared to serological testing.
Politik der Gerüchte: Dramen von Gryphius bis Kleist im medien- und öffentlichkeitsgeschichtlichen Kontext
Authors: Dubbels Elke 
Published: October 2024

Gerüchte sind ein politisch brisantes Kommunikationsphänomen. Dramen von der Frühen Neuzeit bis zum Beginn des 19. Jahrhunderts inszenieren, reflektieren und kommentieren es auf erhellende Weise. Die politische Wirkungsmacht von Gerüchten ist ambivalent: Sie können Aufstände provozieren, aber auch von Regierungen absichtsvoll verwendet werden. Die politische Virulenz von Gerüchten ist bereits in der Frühen Neuzeit erkannt und in barocken Trauerspielen dramatisch verarbeitet worden. In einer breit angelegten Studie, die kommunikationstheoretisch orientierte Dramenanalysen mit medien-, wissens- und öffentlichkeitsgeschichtlichen Herangehensweisen verbindet, untersucht Elke Dubbels, wie Gerüchte in Dramen von der Mitte des 17. bis zum Beginn des 19. Jahrhunderts als Kommunikationsgeschehen dargestellt werden. Im Anschluss an einen systemtheoretisch inspirierten Begriff von Öffentlichkeit als »beobachteter Beobachtung« (Schlögl) werden Dramen als Reflexionsmedium politischer Öffentlichkeit erschlossen. Im Zentrum steht die Frage, wie die Stücke Gerüchte in Szene setzen und sich zu der von ihnen dargestellten Öffentlichkeit verhalten. Es zeigt sich, dass die untersuchten Dramen ihre Leser*innen nicht nur für die politische Bedeutung von Gerüchten sensibilisieren und sich von diesen abgrenzen, indem sie ihnen andere Modelle der Kommunikation gegenüberstellen. Vielmehr beteiligen sie sich zum Teil auch performativ an den gerüchtegetriebenen Meinungskämpfen, die sie darstellen.
Институт биомедицинских исследований ВНЦ РАН: история создания, ученые, важнейшие достижения, перспективы развития
Authors: Ф.С. Датиева 
Published: October 2024

В статье представлены основные этапы истории Института и перспективы развития основных научных направлений. Дана информация о структурных подразделениях института,показаны главные результаты деятельности.
The article presents the main stages of the history of the Institute and the prospects for the development of the main scientific directions. Information about the structural divisions of the institute is given, and the main results of its activities are shown.
LA FINANCIACIÓN DE LAS DIPUTACIONES PROVINCIALES
Authors: Rodríguez García Juan 
Published: October 2024

Este capítulo revisa la historia de las provincias y las Diputaciones Provinciales como figuras para la administración del territorio español. Tras esto, podremos encontrar un examen del papel competencial y de la financiación de las Diputaciones Provinciales. SUMARIO: 1. Introducción. 2. Origen y evolución histórica de las Diputaciones Provinciales. 3. Competencias de las Diputaciones Provinciales. 4. Estructura financiera y financiación de las Diputaciones Provinciales. - A. Recursos Tributarios. - B. Participación en los Tributos del Estado (PIE). - C. Subvenciones. - D. Precios Públicos. - E. Otros Recursos. - Bibliografía.
LA LEY DE ESTABILIDAD PRESUPUESTARIA: IMPLICACIONES PARA LA POLÍTICA DE ENDEUDAMIENTO Y LA FINANCIACIÓN EXTRAPRESUPUESTARIA
Authors: Faces García Fernando 
Published: October 2024

Este artículo es un análisis del impacto de la regla de oro de la Hacienda Pública en las Haciendas Territoriales, atendiendo especialmente al déficit y deuda públicos y a las nuevas vías por las que se mueve la economía pública:, financiación extrapresupuestaria y gestión público-privada. SUMARIO: 1. Introducción. 2. La Ley de Estabilidad Presupuestaria y el endeudamiento de los Gobiernos territoriales. 3. El concepto de estabilidad presupuestaria. 4. Ámbito de aplicación de la Ley de Estabilidad. 5. Órganos responsables de la formulación y control. 6. El concepto de deuda pública en la Ley de Estabilidad Presupuestaria. 7. estabilidad presupuestaria y capacidad de endeudamiento territorial. 8. Implicaciones del SEC 95 y la Ley General de estabilidad presupuestaria: la financiación extrapresupuestaria. Bibliografía.
LA POLÍTICA DE ENDEUDAMIENTO DE LAS COMUNIDADES AUTÓNOMAS: TEORÍA, MARCO LEGAL Y FINANCIERO, ESTRUCTURA Y EVOLUCIÓN
Authors: Faces García Fernando 
Published: October 2024

En este estudio se trata la justificación académica, el desarrollo normativo, la evolución temporal y el análisis del endeudamiento de las Haciendas Territoriales. Se incide en que los problemas del endeudamiento son más bien fruto de la falta de coordinación entre niveles que de otras causas; habiendo contribuido el mercado financiero, implacable, a racionalizar las soluciones hasta que la coordinación y el autocontrol han aparecido. SUMARIO: 1. Introducción. 2. La justificación académica. 3. Mercados financieros y límites de endeudamiento. 4. Evaluación de la normativa y límites de endeudamiento autonómico. 5. El marco legal autonómico. 6. La Ley de Estabilidad Presupuestaria y las políticas de endeudamiento de las Comunidades Autónomas. 7. El concepto de Estabilidad Presupuestaria y la capacidad de endeudamiento de las Administraciones Territoriales. 8. Evolución del endeudamiento autonómico: magnitud, estructura, diversificación y sostenibilidad. 9. Conclusiones. Anexos. Bibliografía.
EL FUTURO DE LAS HACIENDAS LOCALES EN ESPAÑA
Authors: Vallés Ferrer José 
Published: October 2024

Este capítulo nos presenta unas Haciendas Locales olvidadas en la descentralización. El autor, en su apuesta por un modelo de financiación múltiple descentralizado, hace referencia a la realidad andaluza y expone que el futuro de la Hacienda Local ha de pasar por la coordinación y el replanteamiento del sistema competencial. SUMARIO: 1. Preámbulo. 2. La Ley reguladora de las Haciendas Locales: un avance insuficiente. 2.1. El caso de Andalucía. 3. El Pacto Local como respuesta a la crisis de las finanzas municipales. 4. Algunas consideraciones.
EL FUTURO DE LAS HACIENDAS LOCALES EN ESPAÑA: EL PACTO LOCAL
Authors: Yerga Cobos Juan Alfonso 
Published: October 2024

Este capítulo examina la historia de la Hacienda Pública Local de la España constitucional y esboza el esquema de ingresos y gastos y la rendición de cuentas en el ámbito local. A partir de ello, plantea su autor un nuevo modo de financiación local, que parte del establecimiento de un verdadero Sistema de Financiación Territorial donde insertar el nivel local. Finalmente nos presenta el autor cuál ha sido la praxis del Pacto Local en Andalucía, desde la perspectiva de la cooperación regional-local, en pos del desarrollo de la sociedad. SUMARIO: 1. Introducción 2. Una aproximación a la Hacienda Local española 3. Hacia un nuevo modelo de financiación local 3.1. En cuanto a los tributos 3.2. En cuanto a las transferencias 3.3. Medidas institucionales y de transición 4. El Pacto Local 4.1. Hacia un nuevo modelo de cooperación entre Gobiernos regionales y gobiernos locales 4.1.1 Acerca de la cooperación regional-local 4.1.2. La dimensión hacendística de la cooperación 4.2. ¿Cómo se ve desde la DGAL? 4.2.1. La estrategia 4.2.2. Las actuaciones 4.2.2.1 El marco de la negociación con las Entidades Locales
ACUERDOS ENTRE EL MINISTERIO DE HACIENDA Y LA FEDERACIÓN ESPAÑOLA DE MUNICIPIOS Y PROVINCIAS EN MATERIA DE FINANCIACIÓN LOCAL. UN COMENTARIO CRÍTICO
Authors: Vallés Ferrer José , Fernández Amador Octavio 
Published: October 2024

Este capítulo aborda algunas dudas que podrían planteárse tras el Acuerdo de 21 de noviembre de 2002 entre el Gobierno de la Nación y la Federación Española de Municipios y Provincias. Dudas en torno a la financiación local y los modelos de descentralización. SUMARIO: 1. Introducción. 2. Un esbozo del contenido del Acuerdo. 3. Un primer comentario crítico sobre el Acuerdo. 4. El Acuerdo en la conformación de un marco institucional de la descentralización en España. 5. Recapitulación. Bibliografía