bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unmasking the Hidden Peril: A Case Report of Ankylosing Spondylitis Revealing a Giant Aortic Aneurysm
Authors: Manel Boudoukhane , Ichrak Oueslati , Hiba Bettaieb , Rim Bourguiba , Wiem Helali , Hedi Doggui Mohamed , Syrine Belakhel 
Published: November 2024

Background:
Ankylosing Spondylitis is a chronic inflammatory rheumatic disease with
both articular and extra-articular features. While cardiovascular involvement in Ankylosing
spondylitis is rare, it can be life-threatening. This condition is typically associated with the HLAB27
antigen and often presents in the advanced stages of the disease.
This case is particularly uncommon as cardiovascular involvement was identified at the time of diagnosis
in a patient who tested negative for HLA-B27.

Case Presentation:
Here, we present an uncommon case of a 37-year-old male with 3 years of
evolving Ankylosing Spondylitis negative for HLA-B27, who was incidentally found to have a
giant aortic aneurysm during cardiovascular screening at the time of his rheumatic disease diagnosis.
The patient underwent surgical intervention using the Tyron-David procedure. Subsequent
post-operative follow-ups revealed satisfactory outcomes without complications,

Conclusion:
Even in the absence of clinical signs, and even in the early stages of Ankylosing
spondylitis, it is necessary to screen for this condition, at least with transthoracic ultrasound. Early
screening ensures prompt treatment, which will save the patient’s life.
The Efficacy of Two Triple Therapy Regimens and One Quadruple Regimen [Omeprazole, Amoxicillin, Metronidazole with Bismuth] in Eradicating
Helicobacter Pylori in Patients with Peptic Ulcer: A Randomized Clinical Trial
Authors: Salehi Amir Mohammad , Ebrahimi Alireza , Hasanzarrini Maryam , Khanlarzadeh Elham , Bahrami Anvar 
Published: November 2024

Background:
Helicobacter pylori [H. pylori] infection is the main cause of most PUD;
therefore, the eradication of H. pylori is extremely important in the treatment of PUD. There are
several recommended treatment regimens suggested to eradicate this organism.

Aim:
This study compared the efficacy of three anti-Helicobacter pylori regimens in patients with
dyspepsia or peptic ulcer disease [PUD].

Objective:
The objective of this study was to assess the efficacy of three anti-H Pylori treatments
in patients based on C14 urease breath test [C-UBT] results, drug compliance, and adverse effects.

Methods:
This randomized, open-label clinical trial included 136 H. Pylori-infected patients without
prior treatment. Patients were randomly divided into three groups. The OAC group received
20 mg Omeprazole capsules twice a day, two 500 mg Amoxicillin capsules twice a day, and 500
mg Clarithromycin capsules twice a day for 14 days. The OAL group received 20 mg Omeprazole
capsules twice a day, two 500 mg Amoxicillin capsules twice a day, and Levofloxacin 500 mg capsules
twice a day for 14 days. The OAMB group received 20 mg Omeprazole capsules twice a
day, two 500 mg Amoxicillin capsules twice a day, Metronidazole 500mg three times a day, and
Bismuth 240 mg twice a day for 14 days. Evaluation for compliance and drug-related adverse effects
were assessed at the end of two weeks. H. Pylori eradication was evaluated eight weeks after
treatment using the C-UBT.

Results:
A total of 136 patients participated in this study, and their groups were matched based on
age and sex. The results of the C-UBT test showed that the eradication rate of H. Pylori was
82.2%, 91.3%, and 97.3% for the three-drug OAC, OAMB, and OAL treatment regimens, respectively.
Moreover, all the regimens showed high compliance among the patients. Only OAC and
OAL showed a significant difference in the H. Pylori eradication rate, and no superiority was
found between OAMB and OAL or OAC therapies.

Conclusion:
The regime of OAL achieved a satisfactory rate of H. pylori infection eradication
with good tolerance in patients with PUD, without any acute side effects.

Clinical Trial Registration Number:
IRCT201605189014N100.
Mucormycosis and COVID-19: Unraveling the Interplay of Fungal Infection in a Global Health Crisis: An Overview
Authors: Moheb-Alian Ali , Akbari Ali , Nooraei Saghi , Bahrulolum Howra , Farsani Zoheir Mohammadian , Mokhtari Negin , Ebadi Mozhdeh Sadat , Farsani Arezoo Mohammadian , Khatami Seyedmoein , Esmaeili Mohammadmahdi , Keykhaee Zahra , Heydargoy Mohammad Hossein , Rafiei Zahra , Ahmadian Gholamreza 
Published: November 2024

Abstract:
The healthcare system has been greatly affected by the COVID-19 pandemic, result-ing in an increase in secondary and co-infections among patients. Factors like pulmonary dam-age and weakened immune systems make patients more susceptible to fungal infections. Mu-cormycosis, an opportunistic fungal infection, prospers in environments with limited oxygen, and elevated glucose levels due to conditions such as diabetes and steroid use, as well as in acidic environments from metabolic acidosis and diabetic ketoacidosis, where it demonstrates heightened germination ability. Recognizing these complications is critical to minimize harm to patients. The insights gained from this review can improve our understanding of how fungal infections develop in connection to COVID-19, leading to better predictive algorithms, tailored care plans, enhanced antifungal treatments, quicker diagnostics, and improved management strategies.
Microcrystalline Cellulose Extracted from Tissue Paper and its Comparison to Commercial Microcrystalline Cellulose
Authors: Mehta Himanshu , Tewari Srishti , Gorade Vikrant G. , Chaudhary Babita U. , Pattanaik Jasam , Khilari Vishal , Meshram Rohan C. , Kale Ravindra D. 
Published: November 2024

Introduction:
Tissue paper has been utilized to extract Microcrystalline Cellulose
(MCC) using sulphuric acid. The two approaches used for MCC extraction were with NaOH pretreatment
(NaOH-EMC) and without NaOH (EMC).

Method:
The extracted MCC was characterized by FTIR, SEM, TGA, XRD, zeta potential, particle
size, and degree of polymerization and then subsequently compared with the commercially
available MCC(CMC). The particle size of the NaOH-EMC was lesser than the CMC, while the
EMC had a larger size. The values recorded were respectively 1.322, 6.750, and 8.521 μm. The
SEM images also supported the values reported by the particle size analyzer.

Result:
The distribution, however, was staggered for the prepared samples, as against the CMC.
The prepared MCC suspensions were found to be more stable than the CMC based on the recorded
zeta potential. The crystallinity for NaOH-EMC, EMC, and CMC was recorded to be
69.91, 68.59, and 70.89 percent, respectively, and the observations were not significantly different.

Conclusion:
The degree of polymerization of NaOH-EMC and EMC was 129 and 94, which
was 189 lower than that of CMC, having the value of 178. The study successfully reports the
extraction of MCC from the tissue paper as an alternative source.
Sex-Specific Trends in the Prevalence of Osteoarthritis and Rheumatoid Arthritis From 2005 to 2021 in South Korea: Nationwide Cross-Sectional Study
Authors: Park Seoyoung , Son Yejun , Lee Hyeri , Lee Hayeon , Lee Jinseok , Kang Jiseung , Smith Lee , Rahmati Masoud , Dragioti Elena , Tully Mark A , Fond Guillaume , Boyer Laurent , Lee Jun Hyuk , Pizzol Damiano , Park Jaeyu , Woo Selin , Yon Dong Keon 
Published: November 2024

Background
Osteoarthritis and rheumatoid arthritis (RA) are prevalent chronic joint disorders, with prevalence rates varying by sex. However, few studies have comprehensively documented the factors contributing to the sex-specific prevalence of osteoarthritis and RA, including sociological factors and the impact of the COVID-19 pandemic.

Objective
This study aims to identify long-term trends in the sex-specific prevalence of osteoarthritis and RA from 2005 to 2021 while examining the factors that serve as vulnerabilities specific to each sex within the context of the COVID-19 pandemic.

Methods
Data were collected from a nationally representative sample of 110,225 individuals through the Korea National Health and Nutrition Examination Survey from 2005 to 2021. The study included patients aged 19 years and older diagnosed with osteoarthritis or RA in South Korea. Data were analyzed using weighted trends to accurately represent the sample population, with a 95% CI. Weighted logistic and regression models were used to identify vulnerable groups at risk of osteoarthritis or RA during the pandemic to assess sex-specific trends.

Results
In total, 110,225 individuals (n=48,410, 43.92% male participants) were analyzed from 2005 to 2021, with prevalence rates remaining stable over time and higher in female than in male participants. Notably, during the pandemic, female participants aged 60 years and older exhibited a prevalence of osteoarthritis that was 4.92 times greater than male participants and a prevalence of RA that was 6.44 times greater (osteoarthritis: prevalence ratio [PR] 69.78, 95% CI 41.66-116.88; RA: PR 17.27, 95% CI 8.75-34.07). In terms of osteoarthritis, male participants did not show a significant association with BMI (PR 1.40, 95% CI 1.21-1.61; P=.47), whereas female participants exhibited a significantly higher vulnerability within the obese group (PR 1.68, 95% CI 1.55-1.83; P<.001). Regarding RA, lower education levels were associated with increased vulnerability, with male participants showing a greater risk than female participants (male participants: PR 2.29, 95% CI 1.61-3.27 and female participants: PR 1.50, 95% CI 1.23-1.84).

Conclusions
This study reveals that women in South Korea have a higher prevalence of osteoarthritis and RA than men. Understanding these sex-specific trends and identifying vulnerability factors can enhance preventive efforts and patient care.
Management Control During and After a Crisis: Taking Stock and Looking Ahead
Authors: Carter Mary Ellen , Speklé Roland F. 
Published: November 2024

ABSTRACT
In this introductory article to the Special Interest Forum, we provide a broad overview of the literature on management control during times of crisis. We discuss key themes from studies that emerged following the financial crisis, as well as existing research addressing the management control implications of the COVID-19 pandemic, to offer a background for the papers in the Special Interest Forum. The articles in this Forum highlight the critical role of human capital during crises and emphasize how management control can help mitigate the negative impact of a crisis.
ASSOCIAÇÃO ENTRE BIOMARCADORES DO DECLÍNIO COGNITIVO SUBJETIVO, COMPROMETIMENTO COGNITIVO LEVE E DO ALZHEIMER
Authors: Batista Iany Tâmilla Pereira , Oliveira Izabel Cristina Fernandes de , Oliveira Luis Adriano Freitas , Gonçalves Rosana Ávila , Junior Francisco Raimundo Silva 
Published: November 2024

O objetivo do presente estudo foi buscar na literatura biomarcadores comuns ao declínio cognitivo subjetivo, comprometimento cognitivo leve e doença de Alzheimer. A pesquisa seguiu uma metodologia de revisão bibliográfica rigorosa. Incluíram-se artigos publicados entre 2019 a 2023, independentemente do idioma, disponíveis na íntegra, que abordesse na prática bases moleculares direcionadas à DCS, CCL e DA. Encontraram-se 555 artigos, sendo 374 na base de dados Pubmed e 181 na base de dados Cochrane. A amostra final foi composta por 9 estudos. Como resuldado as pesquisas trouxeram variação de biomarcadores em estudos de métodos bem estabelecidos. Dos nove estudos seis avaliou as três condições, o DCS, o CCL e DA, e destes, dois utilizou substância presente no plasma para comparar as condições. Um deles além de utilizar aprendizado de máquina para avaliar os participantes. O estudo conclui que para detectar neuropatologias nas suas fases iniciais, antes do início de alterações cognitivas significativas, possivelmente os investigadores serão solicitados a utilizar as mais variadadas formas de avaliação em um ritmo cada vez mais acelerado.
S-Adenosylmethionine Treatment Diminishes the Proliferation of Castration-Resistant Prostate Cancer Cells by Modulating the Expression of miRNAs
Authors: Schmidt Thomas 
Published: November 2024

Abstract
AdoMet (S-adenosylmethionine) inhibits cancer cell proliferation and migration via epigenetic alterations. This study aimed to investigate whether AdoMet may cause alterations in microRNA (miRNA) expression profiles that are important for the initiation and progression of prostate cancer. PC-3 cells were treated with AdoMet before miRNA sequencing. A total of 17 differentially expressed miRNAs were detected. Target gene prediction was performed by means of databases. Results were aligned to transcriptomic data. The bioinformatic analysis revealed upregulation of anticancerogenic genes, downregulation of cancerogenic-related processes and pathways. Knocking down hsa-miR-192-5p in PC-3 cells resulted in downregulation of cancer cell proliferation, thus confirming these results.
Lithuanian Landscape Photography of the 20th Century: Place Towards Space
Authors: Matulytė Margarita 
Published: November 2024

Summary
This article analyses Lithuanian landscape photography that reflects the cultural landscape of the 20th century, revealing not only the natural phenomena of the land, but also the historical development of the country, social memory and national identity. Landscape photographs are abundant with cultural codes implicated in visual structures of landscapes, which are read and distinguished with the help of the palimpsest model. An interdisciplinary methodological approach is applied to the understanding of the functioning of photography in the spatial and local planes and to the purposeful use of the concepts of place and space, combining the phenomenological insights of humanistic geography, the theory of spatial production of the sociologist Henri Lefebvre, and the art historical analysis of visual texts. This interdisciplinary study introduces the cultural layer that is characteristic of the 20th century landscape, provides a sense of historical time shifts, and clarifies the prevailing stylistic movements in photographic landscapes.
A minimalist cardio-oncology service: A personal experience from Wales
Authors: Riaz Muhammad Hamza , Barrington Craig , Ionescu Adrian 
Published: November 2024

Abstract
Cardio-oncology is intensely ‘hyped’ in cardiology circles, and there are good reasons for advocating a formal integration of the 2 specialties, but so far evidence of a benefit from the collaboration has not emerged. We provide a simplified blueprint for a ‘minimalistic’ service, based on our own practice and experience in Wales, UK.
Pemasaran Media Sosial, Ulasan Pelanggan, dan Kesadaran Merek terhadap Keputusan Pembelian Xiaomi
Authors: Syahri Anggun Aisyah , Djakasaputra Arifin 
Published: November 2024

Tujuan dari penelitian ini adalah mengetahui apakah pemasaran media sosial, ulasan pelanggan online dan kesadaran merek berpengaruh terhadap keputusan pembelian. Sampel yang diambil dari penelitian ini adalah 195 pengguna smartphone Xiaomi di Jakarta.
Metode purposive sampling digunakan dengan cara menyebar kuesioner secara online, kemudian diolah dengan menggunakan smartPLS-SEM. Hasil dari penelitian ini adalah pemasaran media sosial berpengaruh positif dan signifikan terhadap keputusan pembelian. Kemudian ulasan pelanggan online memiliki pengaruh positif tetapi signifikan terhadap keputusan pembelian. Kesadaran merek memiliki pengaruh positif dan signifikan terhadap keputusan pembelian.

The purpose of this study is to determine whether social media marketing, online customer reviews and brand awareness influence purchasing decisions. The sample taken from this study was 195 Xiaomi smartphone users in Jakarta. The purposive sampling method was used by distributing questionnaires online, then processed using smartPLS-SEM. The results of this study are social media marketing has a positive and significant effect on purchasing decisions. Then online customer reviews have a positive and significant influence on purchasing decisions. Brand awareness has a positive and significant influence on purchasing decisions.
Orientasi Pasar dan Keunggulan Produk Baru pada UKM Tekstil Jakarta
Authors: Christopher Christopher , Wijaya Andi 
Published: November 2024

Penelitian ini mengeksplorasi dampak orientasi pasar pada Usaha Kecil dan Menengah (UKM) tekstil terhadap keunggulan produk baru, serta peran moderasi dari kemampuan inovasi. Hasil temuan menunjukkan bahwa Orientasi Pelanggan berkontribusi positif yang signifikan terhadap Keunggulan Produk Baru. Kemampuan Inovasi memiliki dampak moderasi positif yang signifikan, memperkuat hubungan antara Orientasi Pelanggan dan Keunggulan Produk Baru. Meskipun Orientasi Kompetitif memberikan dampak negatif yang signifikan pada Keunggulan Produk Baru, Kemampuan Inovasi memiliki efek moderasi positif yang mengoptimalkan keterkaitannya. Selain itu, Koordinasi Antar-Fungsional memiliki dampak positif yang signifikan terhadap Keunggulan Produk Baru, dan Kemampuan Inovasi berfungsi sebagai moderasi negatif yang memoderasi hubungan antara keduanya. Implikasinya, strategi holistik yang mengintegrasikan orientasi pelanggan, kemampuan inovasi, dan koordinasi antar-fungsional menjadi kunci untuk mencapai keunggulan produk baru yang berkelanjutan dalam konteks UKM tekstil.

This research explores the impact of market orientation in textile Small and Medium Enterprises (SMEs) on new product advantages, as well as the moderating role of innovation capability. The findings show that Customer Orientation makes a significant positive contribution to New Product Excellence. Innovation Capability has a significant positive moderating impact, strengthening the relationship between Customer Orientation and New Product Advantage. Although Competitive Orientation has a significant negative impact on New Product Advantage, Innovation Capability has a positive moderating effect that optimizes its interrelationship. In addition, Inter-Functional Coordination has a significant positive impact on New Product Advantage, and Innovation Capability functions as a negative moderator that moderates the relationship between the two. The implication is that a holistic strategy that integrates customer orientation, innovation capabilities and inter-functional coordination is the key to achieving sustainable new product excellence in the context of textile SMEs.
Pengaruh Pemanfaatan Media Sosial, Inovasi dan Modal Usaha terhadap Keberlanjutan Usaha
Authors: Chai Misshell , Handoyo Sarwo Edy 
Published: November 2024

Tujuan penelitian ini adalah untuk mengetahui dan menganalisis pengaruh pemanfaatan media sosial, inovasi dan modalk usaha terhadap keberlanjutan usaha UMKM di Jakarta Barat. Metode penentuan sampel menggunakan metode non probability sampling
dengan jenis purposive sampling. Metode pengumpulan data dengan menggunakan kuesioner yang di bagikan kepada 100 responden. Analsis data menggunakan analisis SEM PLS. Hasil analisis menyimpulkan bahwa terdapat pengaruh pemanfaatan media sosial, inovasi dan modalk usaha terhadap keberlanjutan usaha UMKM di Jakarta Barat.

The aim of this research is to determine and analyze the influence of the use of social media, innovation and business capital on the sustainability of MSME businesses in West Jakarta. The sample determination method uses a non-probability sampling method with purposive sampling type. The data collection method used a questionnaire which was distributed to 100 respondents. Data analysis used SEM PLS analysis. The results of the analysis conclude that there is an influence of the use of social media, innovation and business capital on the sustainability of MSME businesses in West Jakarta.
Pengaruh Pendidikan Kewirausahaan, Orientasi Kewirausahaan dan Kepercayaan Diri terhadap Intensi Kewirausahaan Hijau
Authors: Angelia Sherafina , Hidayah Nur 
Published: November 2024

Penelitian ini bertujuan untuk menguji secara empiris pengaruh pendidikan kewirausahaan, orientasi kewirausahaan dan kepercayaan diri terhadap intensi kewirausahaan hijau. Teknik pengambilan sampel menggunakan metode purposive sampling dengan teknik pengambilan data menggunakan kuesioner melalui google form dengan jumlah 165 responden mahasiswa yang sudah mengikuti mata kuliah kewirausahaan dan telah menentukan konsentrasi pada jurusan Manajemen (pemasaran, sumber daya manusia, keuangan dan kewirausahaan) di semester 4 Universitas Tarumanagara. Kemudian, data analisis penelitian ini menggunakan pendekatan metode Partial Least Square – Structural Equation Modeling (PLS-SEM) dengan software SmartPLS versi 4.0.9.6. Hasil dari penelitian ini menunjukkan pendidikan kewirausahaan, orientasi kewirausahaan dan kepercayaan diri berpengaruh positif terhadap intensi kewirausahaan hijau mahasiswa di Universitas Tarumanagara.

This study aims to test empirically the effect of entrepreneurial education, entrepreneurial orientation and self-confidence to green entrepreneurial intention. The sampling technique used purposive sampling method with data retrieval techniques using questionnaires through google form a total of 165 student respondents who have attended entrepreneurship courses and have determined concentrations in the Management (marketing, human resources, finance and entrepreneurship) in the 4th semester Universitas Tarumanagara. Then, the research analysis data uses the Partical Least Square method – Structural Equation Modeling (PLS-SEM) with SmartPLS version 4.0.9.6. The results of this study show entrepreneurial education, entrepreneurial orientation and self-confidence have a positive effect on the green entrepreneurial intention student at Universitas Tarumanagara.
STUDI PERENCANAAN ANGKUTAN PENUMPANG KE TERMINAL NGANJUK SEBAGAI PENUNJANG KEBUTUHAN TRANSPORTASI KARYAWAN YANG BEKERJA DI SURABAYA
Authors: Hasanah Fifi Nurlaili , Utomo Nugroho , Wibisana Hendrata 
Published: November 2024

Terminal Nganjuk merupakan terminal tipe A yang memberikan fasilitas dan sarana bagi angkutan umum maupun pelaku perjalanan transportasi. Terminal Nganjuk merupakan tujuan dari angkutan antar kota ataupun angkutan pedesaan untuk memenuhi kebutuhan pelaku perjalanan. Karyawan yang berasal dari desa yang ingin bekerja di Surabaya biasanya berangkat dari daerah asal menuju terminal banyakmenggunakan kendaraan pribadi, ojek, atau becak. Ditinjau dari angkutan umum yang digunakan dari desa menuju Terminal Nganjuk belum ada. Penulis melakukan studi perencanaan angkutan penumpang menuju Terminal Nganjuk guna untuk memenuhi kebutuhan transportasi . Penelitian ini dilakukan pada lokasi zona 1 Gondang – Terminal Nganjuk dan zona 2 Rejoso – Terminal Nganjuk dengan cara survei lapangan yakni membagikan kuisioner kepada 100 responden dengan disertai wawancara, survei rumah tangga, serta dilakukan secara rutin pengumpulan data primer dan sekunder pada tanggal 13 – 18 Maret 2023 di lokasi Terminal Nganjuk. Dari kuisioner tersebut didapatkan data karakteristik sosial ekonomi responden dan karakteristik perjalanan responden. Pada perencanaan angkutan pemadu moda diperoleh load factor pada zona 1 dan zona 2 sebesar 0.7, kecepatan perjalanan rencana pada zona 1 dan zona 2 sebesar 30 km/jam, waktu sirkulasi pada zona 1 sebesar 70.19 menit dan waktu sirkulasi pada zona 2 sebesar 58.73 menit, headway di zona 1 dan zona 2 sebesar 5.5 menit, frekuensi pada kedua zona tersebut sebesar 8 kendaraan, waktu tunggu maksimum pada kedua zona sebesar 5.5 menit dan angkutan yang dibutuhkan pada zona 1 yaitu sebesar 13 kendaraan serta kebutuhan angkutan pada zona 2 sebesar 11 kendaraan. Tarif penumpang pada angkutan mikrobus berkapasitas 16 kursi untuk zona 1 yakni sebesar Rp. 4,200,00/Pnp dan zona 2 yakni sebesar Rp. 4,000,00/Pnp.