bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Family Relations on a Sample of Egyptian Patients with Substance Use Disorder
Authors: El-ella Eman Ibrahim Abo , Elsheikh Mona Mahmoud , Ghamry Reem Hassan El , Ghobrial Phoebe Fayez , El-Maseh Sara Rafat Abd 
Published: November 2024

Abstract

Background
Substance use disorders (SUD) present a complex condition characterized by uncontrolled substance use despite adverse consequences, often intertwined with social and family problems. Dysfunctional family relationships, including violence, stress, parental drug use, and poor communication, have been linked to adolescent drug use. The current study investigates the association between family relation dysfunction and substance use, aiming to understand the quality of this connection.

Aim of the Work
This case - control study aims to examine the relationship between family relations and substance use, assessing the impact on the type and severity of substance abuse. Specific objectives include exploring the association between family dysfunction and SUD, comparing family interaction in SUD patients and normal individuals, and evaluating variations in family interaction based on sociodemographic factors.

Patients and Methods
Seventy participants, comprising 35 SUD patients and 35 healthy controls, were recruited from EL-Abbsia Mental Health Hospital. Participants were assessed using socio- demographic data sheets, Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Quality of Family Relationships Scale (KOBI), and Addiction Severity Index. Urine tests were conducted for psychoactive substances. Statistical analysis involved various tests, including t-tests, Mann-Whitney, chi-square, and correlation analyses.

Results
The study revealed a significant prevalence of smoking among SUD patients compared to controls, along with longer smoking duration and higher daily cigarette consumption. SUD patients exhibited increased medical issues and higher incidences of substance use, particularly cannabis and heroin. Family rejection and non-acceptance were significantly higher in SUD cases, correlating with the severity and duration of substance abuse.

Conclusion
The findings underscore the significant connection between family relationship dysfunction and substance use. Rejection and non-acceptance within the family environment emerge as crucial predictors of addiction. The study highlights the need for comprehensive interventions addressing family dynamics in substance abuse treatment.
Sexual Dysfunctions and Psychiatric Correlates among a Sample of Egyptian Female Patients with Ischemic Heart Diseases Following Percutaneous Coronary Intervention
Authors: Wahba Shenouda Abdelshahid , Sayed Maha Mohammed , Rahman AL-Moghazi Marwa Abdel , Mohamed Mariam Yehia , Saber Hafez Mohamed 
Published: November 2024

Abstract

Background
Female sexual dysfunction is a wide range of illnesses that can affect a patient's capacity to respond to or enjoy sexual activity in orgasm, interest/arousal, or Genito-pelvic pain/penetration which occurs most of the time and represents a problem to the patient (in DSM5 TR).

Aim of the Work
To assess the correlation between ischemic heart disease and female sexual function in patients who underwent percutaneous female intervention in the last year. To study the risk factors of female sexual dysfunction after percutaneous coronary angiography in group 1. To assess the correlation between ischemic heart disease and depression, anxiety and post-traumatic stress disorder in patients who underwent percutaneous female intervention in the last year

Patients and Methods
This study is a comparative cross-sectional study. This study conducted at cardiology outpatient Clinics at Ain Shams University Hospital. Ain Shams University is in Cairo and serves a catchment area of about the third of Greater Cairo. It serves both urban and rural areas, including areas around Greater Cairo as well. The Study period from March 2023 till end of the study.

Results
Both groups showed 100% of cases have sexual dysfunction regardless undergoing intervention or not with no statistical difference between both group neither regarding the total score or each domain score and this may be explained by presence of worsening factors in both groups like presence of chest pain, most of patients are menopausal (60% in each group) with the most important factors seen in our study is the cultural concepts among women to have sexual relation in presence of chronic disease like ischemic heart disease and this has been shown when looking deeply in the patients we will found 7 patients (23.3%) who underwent the intervention scored only 2 in FSFI total score which is the minimal (indicating lack of any sexual activity in spite of presence of partner) with the same number seen in the group which didn’t undergo the intervention this rate of having sexual activity.

Conclusion
Comprehensive examination of the impact of sexual dysfunction, PTSD, depression, and anxiety in patients with ischemic heart disease, and how these factors interrelate with each other as well as with the intervention of stenting or angioplasty. The finding that sexual dysfunction is universally present across your study groups, regardless of intervention, underscores the complexity of sexual health in the context of chronic diseases.
Risk of Suicide in a Sample of Egyptian Male Patients with Substance Use Disorder during Covid-19 Pandemic
Authors: El Masry Shereen Hatem Anwar , Okasha Tarek Ahmed , Abd Elazziz Mohamed Fekry , Naguib Rehab Mohamed , Tawfik Fairouz Ahmed 
Published: November 2024

Abstract

Background
Suicide is a global burden among the leading causes of death.

Aim of the Work
This study aimed to investigate the suicide risk in male substance abuse patients during the COVID-19 pandemic.

Patients and Methods
This study is a Cross-sectional descriptive study was approved by the ethical committee of the Department of Neuropsychiatry, Faculty of Medicine, Ain Shams University, conducted at Okasha Institute of Psychiatry, Faculty of Medicine, Ain Shams University Hospitals which is located in Cairo and serves a catchment area of about the third of Greater Cairo. It serves both urban and rural areas, including areas around Greater Cairo as well.

Results
Personality disorders, borderline personality disorder, and antisocial personality disorder were significantly associated with death wish, ideation, and suicide attempts. Individuals with polysubstance were more likely to have suicidal thoughts and behaviors. Family history of addiction was significantly associated with increased suicide risk.

Conclusion
It is important to underscore the importance of comprehensive assessment, early intervention, and ongoing support to mitigate this risk and promote long-term recovery and well-being.
Burnout Syndrome among Family Caregivers of Hemodialysis Patients in Luxor International Hospital
Authors: Mohamed Wael Alraey , Hosam Mohamed , Mohamed Mariam Yehia , Sayed Maha Mohamed 
Published: November 2024

Abstract

Background
Chronic illness caregivers experience sadness, anxiety, drug usage, physical deterioration, and poor quality of life. Burnout from lack of support affects family, professional, and social life. Hemodialysis stresses caregivers, who stop work for long-term care. Burnout is caused by long hours, interpersonal challenges, and unpredictability. Chronic stress may impact quality of life with physical and mental symptoms.

Aim
To assess burnout in hemodialysis family caregivers, factors contributing, including sociodemographics, job aspects, and burnout's impact on their quality of life.

Methods
This cross-sectional study at Luxor International Hospital, starting January 2023, includes 100 participants, caregivers, and healthy individuals linked to regular hemodialysis patients. Participants will complete a questionnaire covering sociodemographic information and four validated measures assessing burnout, stress, mental health, and quality of life. Interviews with family caregivers will collect further data and include these questionnaires (CBI, PSS- 10,GHQ-28,WHOQOL Bref).

Results
The average age of research participants is 42.39. Based on CBI ratings, 78% have little personal burnout. Age affects burnout and mental health. Personal burnout is gendered. Burnout and mental anguish are linked to work hours. Marital status affects psychology. Education affects burnout and life quality. Parenthood influences mental health. Smoking connects with subjective stress but not others.

Conclusion
The study reveals significant burnout, perceived stress, and psychological distress among hemodialysis caregivers. Despite low burnout in most, substantial psychological distress is evident, affecting their quality of life. Factors like age, gender, marital status, education, children, and smoking influence caregiver experiences.
Outcomes after Deep Brain Stimulation for Generalized Dystonia
Authors: Zoghdan Hassan El-Sayed Hassan , Salem Tarek Mohamed Lotfy , Abouelela Abdelmawla Radwan Hesham Mohamed , Youssef El-Mashad Mohamed Gamal 
Published: November 2024

Abstract

Background
Deep Brain Stimulation (DBS) is an already established treatment option for refractory dystonia. Its main targets are currently the globus pallidus internus (GPi) and the subthalamic nucleus (STN) with similar motor and disability outcomes, 50 to 70% in isolated generalized/segmental inherited/idiopathic dystonia. This systematic review and meta- analysis aimed to assess the efficacy outcomes of DBS use in patients with generalized dystonia.

Methods
This study was conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the searched strategy was developed using the Mesh Database to find the similar keywords to the main keywords in our study. We searched PubMed, Web of Science, Scopus, Cochrane Library, and Google Scholar for eligible articles to be included in our study using the following search strategy: (Brain Stimulations OR Deep Brain Stimulations OR Brain Stimulation OR Deep Brain Stimulation OR Electrical Stimulation of the Brain) AND (movement disorders OR dystonia syndromes OR dystonia).

Results
A total of 25 articles were included in our meta-analysis. The pooled analysis of 25 studies showed the improvement in the BFMDRS-movement score after deep brain stimulation as evident by the decrease in the pos-DBS values with an overall mean difference of -25.96 (95%CI: -29.24 - -22.69, p &lt; 0.00001) with moderate heterogeneity (I2=51%, p = 0.002). Regarding BFMDRS-disability score, it was statistically significant reduced after deep brain stimulation compared to pre-operative values with an overall mean difference of -5.69 (95%CI: -7.04 - -4.35, p &lt; 0.00001) and moderate heterogeneity (I2=50%, p = 0.02).

Conclusion
Our study demonstrated the deep brain stimulation's excellent efficacy across various parameters. This included mobility and disability on the BFMDRS, while the use of DBS is linked to improved post-operative results when compared to pre-operative values. Furthermore, according to the SF-36, which measures both mental and physical performance, DBS has demonstrated a high efficacy on quality of life. Furthermore, DBS was linked to a considerable decline in depressed symptoms, as demonstrated by the BDI score, which dropped dramatically in individuals with generalized dystonia following DBS application.
Safety and Efficacy in Treatment of Ruptured Small Anterior Circulation Aneurysms
Authors: Saleh Mamdouh Shaaban , El-Hussiney El-Hussam , Habib Mohammed Alaa Aldien , Tobar Ahmed Faisal , El-Sayed Ahmed 
Published: November 2024

Abstract

Background
Small aneurysms ≤10 mm in diameter account for almost 6% of all ruptured intracranial aneurysms and pose a therapeutic dilemma for the treating physician. Published studies have investigated the safety and efficacy of endovascular therapy unilaterally without comparison to a surgical group, which limits the value of their findings

Objective
To review of literature and recent publications regarding treatment of the small anterior circulation aneurysms, evaluate the outcome of treatment of small anterior circulation aneurysms in Ain Shams University Hospitals, determine the incidence of various complications, define the good and bad prognostic criteria for outcome and to compare between the variable modalities of treatment of anterior circulation aneurysms

Methods
This prospective study was done in the Neurosurgery Department in Ain Shams University hospital, on 30 patients admitted to the Emergency Unit of Neurosurgery suffering from spontaneous subarachnoid hemorrhage (SAH) due to ruptured small anterior circulation aneurysm.

Results
There was no statistically significant difference found between clipping group and coiling group regarding age, sex, aneurismal size, Hunt & Hess grade and Fisher grading. Also, there was no statistically significant difference found between clipping group and coiling group regarding percentage of complications during procedure. There was no statistically significant difference found between clipping group and coiling group regarding percentage of complications post procedure except pneumocephalus was found with higher percentage in clipping group (33.3%) than coiling group (0.0%) with p-value = 0.014. There was no statistically significant difference found between clipping group and coiling group regarding modified Rankin Scale with p-value = 0.440

Conclusion
Lower procedural complication rates were seen with endovascular therapy as compared to open surgery in small ruptured aneurysm. Overall patient outcomes, however, were similar in both groups. In light of our results, endovascular treatment of small ruptured aneurysm seems to be feasible, safe, and effective and might be a preferred option in this setting. These data provide impetus for further study, in which small ruptured aneurysm need not be excluded from comparisons of coiling and neurosurgical clipping. More specifically, the stage is set for a randomized controlled trial to compare the 2 treatment modalities in patients with small ruptured aneurysm.
A Systematic Review of Comparison of Early Surgical Intervention versus Followup in Management of Adult-Type Diffuse Low Grade Gliomas with No Motor Neurological Deficit in Terms of Survival Rate and Quality of Life: A Systematic Review
Authors: Moustafa Hazem Ahmad , Hamada Salah Moustafa , El-Sabaa Ahmad Mohammed , Khater Omar Ahmad 
Published: November 2024

Abstract

Background
The precise optimal management of patients with low-grade glioma remains to be determined. Active surveillance, needle or open biopsy, as well as surgical resection have all been advocated by different authors. Surgical resection is superior when compared with observation to improve overall survival for patients with LGG (Level III) although observation has no negative impact on cognitive performance and quality of life (Level II).

Objective
To systematically review the available literature discussing the outcome of early resection versus followup on overall survival and quality of life of such patients. With evaluation of the impact of extent of resection on overall survival and the value of utilizing preoperative and intraoperative technical aids (imaging and mapping) on the postoperative functional outcome.

Patients and Methods
Systematic review of published English literature from Jan. 2000 to Jan. 2024.

Results
A total of 10955 citations were retrieved according to our search strategy and review of bibliographies. 10 of these studies met the inclusion criteria and were included in the analysis, 7 were before 2021, 3 were after 2021. They were obtained from Medline via PubMed.

Conclusion
DLGGs management is multimodal and involving the interplay of the treatment modalities. The determination of an optimal treatment plan for a DLGGs patient should be individualized based on the patient’s age, sex, location of tumor, molecular status, and co- morbidities. Besides, putting into consideration the timing (early vs. delayed) of treatment as well as the positive and negative impacts of treatment on survival, quality of life, and seizures control. However, it’s clear that the introduction of the new technical aids, has improved all the outcomes of the surgical resection, rendering it the superior option of the two at the current time.
Anterior Cervical Discectomy and Fusion with and without Plating versus Laminectomy with and without Fusion for Multilevel Cervical Spondylotic Myelopathy: A Comparative Study
Authors: Badr Ashour Wael Mamdouh , Ibraheem Hemeeda Salah Abdel-Khalek , Abdel-Khalek Elserry Tarek Hamdy , Ahmed Ibraheem Omar Elfarok , Mohamed Hisham Elgayaar Abdel-Rahman 
Published: November 2024

Abstract

Background
Cervical spodylotic myelopathy (CSM) is a chronic progressive spinal compression that usually accompanies age-related degeneration of the cervical spine and represents one of the most common causes of spinal cord dysfunction. Surgical intervention is the foundation of management in symptomatic cases, but the approach of choice is constantly contentious.

Purpose
The aim of this study is to evaluate and appraise different surgical approaches for multilevel cervical spondylotic myelopathy (Anterior cervical discectomy and fusion with or without plating and Laminectomy with and without fusion) regarding the perioperative data, clinical outcomes, complications rates and radiographic parameters.

Patients and Methods
This work is a prospective comparative study of 80 patients assigned into four groups. The first group (n = 20) underwent ACDF only, the second group (n = 20) underwent ACDF with anterior plate, the third group (n = 20) underwent laminectomy alone and the fourth group (n = 20) underwent laminectomy with lateral mass fusion. Patients were followed up for 12 months duration using modified Japanese orthopedic score (mJAO), Neck disability index (NDI), Visual analogue scale (VAS) and short form 36 (SF-36) in addition to measurement of C2-C7 cobb`s angle to evaluate post-operative cervical sagittal alignment.

Results
Our results revealed that all the four surgical techniques were associated with functional improvement compared to preoperative parameters. Anterior approaches were associated with better restoration of lordosis and better overall quality of life than posterior approaches.

Recommendations
We recommend designing randomized controlled trials in the future with longer follow-up periods to address long-term outcomes and/or complications.
Diagnostic Accuracy of Tomographic Ultrasound Imaging (TUI) in Depth of Myometrial Invasion and Cervical Stromal Invasion in Endometrial Carcinoma
Authors: Faisal Malames Mahmoud , Ahmed Abdelhamid Sherief Mohamed , Farid Laila Aly , Mohamed Ahmed Saleh Elnabeshy 
Published: November 2024

Abstract

Background
Endometrial cancer (EC) is the most common gynecological neoplasm Of female genital organ in developed countries accounting for 50% of all gynecological cancer. The imaging routine in preoperative assessment of EC differs amongst the gynecologists. The advantages of cross-sectional imaging are taken for granted in computed tomography and magnetic resonance imaging. Recently, tomographic ultrasound has introduced these advantages to sonographic volume imaging.

Aim of the Work
To evaluate the potential accuracy of 3D tomographic ultrasound imaging (TUI) coupled with power Doppler in comparison to computed tomography scan in the detection of depth of myometrial invasion and stromal invasion in endometrial cancer in relation to histopathology.

Patients and Methods
This cross-sectional study (Diagnostic purpose) included fifty biopsied women who are pathologically proven endometrial cancer for two years (December 2018- December 2020). This study conducted at Ain Shams university Maternity Hospital (Gynecology oncology unit)

Results
This study showed that 2D US (Invasion ≥50.0%), Doppler (Feeding vessel), TUI (Coherent vessels), TUI (Margin disruption) and CT (Invasion ≥50.0%) were significantly more frequent in cases with positive cervical stroma invasion. There was no statistical significant difference according to endometrium invasion (histopathology) regarding demographic characteristics and clinical presentation.

Conclusion
Endometrial cancer (EC) is the most common gynecological neoplasm of female genital organ in developed countries accounting for 50% of all gynecological cancer. 3D tomographic ultrasound imaging (TUI) coupled with power Doppler showing significant accuracy in the detection of depth of myometrial invasion and stromal invasion in endometrial cancer in relation to histopathology.
Magnetic Resonance Imaging MRI versus Color Doppler Ultrasound for Assessment of Placenta Accreta Spectrum Disorders
Authors: Ismail Abdel Megeed Abdel Megeed , El Sherbeny Mohammed Mahmoud , Abdelnasser Ahmed Gamal , Mohamed Aya Attia Mohamed 
Published: November 2024

Abstract

Background
As placenta previa and placenta accreta are the two most common causes of postpartum hemorrhage, early and accurate diagnosis, preoperative assessment, and intraoperative management are crucial for a successful outcome. However, risk assessment of intraoperative massive hemorrhage in patients with placenta previa and accreta is challenging in clinical practice.

Aim of the Work
To compare the sensitivity and accuracy of MRI versus color Doppler US in the diagnosis of morbidly adherent placenta in women with placenta previa accreta spectrum.

Subjects and Methods
This was a cohort prospective study was done in cases was recruited from the pregnant women attending outpatient clinic or emergency department at Ain Shams University Maternity Hospital. The study was include 62 pregnant women.

Results
The final US results shows that from the 90 studied patients; 25 patients have no presence of accreta (37.8%) and 65 patients have presence of accreta (72.2%). The final MRI results shows that from the 90 studied patients; 35 patients have no presence of accreta (38.9%) and 55 patients have presence of accreta (61.1%). there was statistically significant increase in the percentage of patients with history of thyroidectomy and IUD removal laparoscopic in patients with placenta accreta (7.5% and 7.5%; respectively) than patients without placenta accreta (0.0% and 0.0%; respectively) with p-value = 0.049 and 0.049; respectively. there was statistically significant increase in the percentage of accuracy of MRI results (73.3%) than ultrasound results (58.9%).

Conclusion
Regarding to our results we concluded that ultrasound can detect patients with placenta accreta with sensitivity of 92.5%, specificity of 32.0% and overall accuracy of 58.9% while MRI can detect patients with placenta accreta with sensitivity of 100.0%, specificity of 52.0% and overall accuracy of 73.3%, there was statistically significant increase in the percentage of accuracy of MRI results (73.3%) than ultrasound results (58.9%) with p-value &lt;0.001.