bluuebunny/crossref_metadata_2025_split huggingface dataset:
QBD-BASED DEVELOPMENT AND EVALUATION OF ENTERIC COATED MUCOADHESIVE MICROCAPSULES OF AMOXICILLIN TRIHYDRATE AS A NOVEL CHRONOTHERAPEUTIC APPROACH FOR TREATMENT OF BACTERIAL INFECTIONS
Authors: Prasad Shyam Narayan , Patel Hemant Kumar , Gothoskar Abhijit V. 
Published: August 2018

Objective: The present work entails design and characterization of enteric coated mucoadhesive microcapsules loaded with amoxicillin trihydrate as a novel chronotherapeutic approaches for the treatment and management of bacterial infection.Methods: The microcapsules were prepared by solvent evaporation technique using ethyl cellulose (EC) and hydroxypropyl methylcellulose (HPMC) as rate-controlling and mucoadhesive polymers, followed by a triple coating with Eudragit L100 as enteric coating polymer. Box-Behnken statistical design (BBD) was applied for optimization of formulations containing EC, HPMCK100M and Eudragit L100 as factors for selected responses like entrapment efficiency, mucoadhesive property and drug release in 24 h. The optimized microcapsules were also characterized for particle size, drug content, swelling index, mucoadhesive strength, and in vivo antiulcer activity.Results: The optimized microcapsules exhibited good entrapment efficiency, particle size and mucoadhesive property. FT-IR studies revealed that there was no drug-polymer interaction. SEM studies revealed that microcapsules were non-aggregated, spherical in shape and smooth appearance. In vitro drug release data from microcapsules was fitted to different kinetic models to explain release profiles. The correlation coefficient (r2) value indicated that drug release followed Higuchi model. Analysis of variance (ANOVA) showed significant difference in the release of drug from all the prepared formulations at P < 0.05 level. Accelerated stability study of optimized formulation (F4) upto 6 month showed there was no change in drug content and release characteristics during storage.
DETERMINAN EFEKTIVITAS IMPLEMENTASI ANGGARAN BERBASIS KINERJA DAN PENYERAPAN ANGGARAN DI PEMERINTAH DAERAH
Authors: Pratama Novrian Dandi , Abdurahim Ahim , Sofyani Hafiez 
Published: August 2018

This study aims to attempt influence of Understanding, Training, and External Pressure to the Effectiveness of Performance-Based Budgeting Implementation and Budget Realization in Province Government of Yogyakarta Special Rebion. Respondents representing the sample are head, secretary, expense treasurer, and head of planning subdepartment of agency at Local Government Unit (SKPD). Data was obtained by questioner dispersion technique to respondent. The collected quistioner was 113. Hypothesis testing employs Structural Equation Model (SEM) approach. The results show that education, understanding, training, and external pressure are the factors that have significant effect on the effectiveness of performance-based budgeting implementation. For budget realization, the understanding and effectiveness of performance-based budgeting implementation are two aspects that have significant effect.
Mapeamento das produções acadêmicas sobre Ensino Religioso na Região Norte do Brasil
Authors: Sanches Vulcão Maria Lourdes , De Freitas Reis Marcos Vinicius , Santos Fonsêca Kátia De Nazaré 
Published: August 2018

Este texto visa mapear as produções acadêmicas que discutem a realidade do Ensino Religioso na região Norte. Percebeu-se a escassez de produções científicas sobre o tema na Amazônia e poucos são os trabalhos que discutem a realidade do profissional de Ensino Religioso nesse contexto. A pesquisa foi realizada nos sites do Google Acadêmico, Banco de Teses da CAPES, Portal de Periódicos/CAPES, das universidades públicas e privadas do Brasil e no Curriculum Lattes de pesquisadores e professores que têmenvolvimento com a temática religião. Identificou-se que boa parte das produções feitas e publicadas por instituições particulares, mantidas por instituições religiosas, não é adstrita à região Norte.
Ensino Religioso e capitais culturais
Authors: Andrade Péricles , Ferreira Ismael De Vasconcelos 
Published: August 2018

Este artigo tem como objetivo propor alternativas às difi culdades de implementação de uma agenda multicultural ao Ensino Religioso, sobretudo a partir das tensões entre os capitais culturais religiosos familiares e escolares. Para isso busca responder algumas questões: como é possível aos professores de Ensino Religioso instituir nos espaços escolares princípios multiculturais para estudantes cujos capitais culturais familiares são constituídos por uma linguagem religiosa naturalizada enquanto sistema simbólico com elementos de totalidade coerente e que absolutiza o relativo e o arbitrário? Como propor um Ensino Religioso para crianças e adolescentes com posse de capitais culturais familiares que transfiguram as instituições sociais em sobrenaturais, estruturam suas vidas a partir desses princípios e conferem às relações sociais função simbólica de conferir a ordem social seu caráter transcendente e inquestionável? Partimos do pressuposto de que o conceito de capital cultural de Pierre Bourdieu, aqui também entendido como consciência prévia que tem na religião sua principal fonte de produção de sentido, se constitui num recurso metodológico fundamental enquanto alternativa a resoluções parciais dessas questões.
Dissertações e teses: exercício para uma identidade da pesquisa sobre o Ensino Religioso
Authors: Azevedo Junqueira Sérgio Rogério , Kluck Cláudia Regina 
Published: August 2018

É por meio da pesquisa que ocorre com método e fontes confiáveis que um objeto pode ser dimensionado efetivamente, de tal forma que pesquisadores em diferentes regiões passam a ter condições de discutir os resultados desses trabalhos. Especificamente, no caso do Ensino Religioso, a pesquisa acadêmica, por meio de dissertações e teses, no cenário brasileiro é recente, um percurso aproximado de quarenta anos em campos como Educação, Ciência da Religião, Teologia, Direito, Antropologia e Sociologia. Buscando estabelecer como se deu a construção desse percurso é que o Grupo de Pesquisa Educação e Religião (GPER) estabeleceu um programa denominado Concepções e Recursos do Ensino Religioso, com o projeto Concepções e Produção Científi ca do Ensino Religioso, cujo objetivo é analisar o contínuo processo de construção da identidade do Ensino Religioso como componente curricular a partir da produção científica sobre esse tema. Este artigo é resultado de tal projeto, visando estabelecer a compreensão das escolhas metodológicas realizadas para favorecer a identificação dos trabalhos sobre o objeto. Organizado em três núcleos, os pressupostos da pesquisa, o contexto e, especificamente, as dissertações e teses sobre Ensino Religioso, objetiva-se estabelecer um percurso para compreender o perfil pelo viés metodológico, ainda que seja ausente ou lacunar a sua verificação, conforme constatado pelos autores.
Pemberdayaan dan Penguatan Daya Saing Usaha dengan Penerapan Lean Six-Sigma Concept, Studi Kasus
Authors: Supriyanto Hari 
Published: August 2018

Dinamika dan perkembangan ekonomi global dapat memberikan sinyal positif terhadap pentingnya peningkatan pemberdayaan dan daya saing produk di pasar. Dibutuhkan pemikiran untuk membangun keunggulan kompetitif, yang menjadi dasar bagi peningkatan produksi dan daya saing bisnis. Peningkatan produksi merupakan serangkaian aktifitas untuk membentuk produktifitas. Bila salah satu aktifitas produksi mengalami kegagalam maka akan berpengaruh pada kualitas dan kapasitas produksi. Kegagalan biasanya terindikasi dari waste/ pemborosan yang muncul di sepanjang value stream. Terdapat indikasi defect yang tinggi melebihi 10% di sortir dan packaging process. Permasalahan utama adalah adanya waste/ pemborosan yang mengakibatkan penurunan kualitas dan kapasitas produksi. Paper ini akan mengidentifikasi waste yang terjadi di proses produksi, mencari akar penyebab terjadinya waste, dan membangun alternatif solusi perbaikan. Diperlukan pemikiran kreatif untuk dapat menaikkan efisiensi sumber daya dan daya saing bisnis di pasar. Metoda yang dipakai untuk menyelesaikan permasalahan adalah Lean six-sigma. Konsep ini menelusuri permasalahan inefisiensi dengan mencari non value added activity dari munculnya waste di sepanjang value stream. Kemunculan waste selanjutnya diidentifikasi lebih dalam dengan root cause analisys (RCA) dan failure mode and effects analysis (FMEA). Hasil akhir dari FMEA adalah risk priority number (RPN) yang menggambarkan prioritas atas mode resiko untuk dilakukan perbaikan. Dari hasil prioritas dirancang 3 alternatif perbaikan yaitu pelatihan operator, pembuatan SOP proses produksi, dan pelatihan karyawan quality control. Dengan pendekatan net present value (NPV), maka diperoleh nilai NPV yang positif, artinya alternatif tersebut adalah layak untuk dijalankan. Alternatif ini meningkatkan nilai sigma dari sigma awal sebesar 2,80 menjadi 3,30. Kenaikan nilai sigma akan memberi indikasi adanya penurunan tingkat defect per million opportunities (DPMO), dan berakibat pada penurunan biaya sampai 20%.
“The Shameless Pain?”: A Maori Mother’s Grief Processing the Effects of Suicide
Authors: Waru Sheryl Mahinarangi 
Published: August 2018

This piece is about my experience of suicide and the systemic epistemology between culture and laws that are structured like a one size fit all ugly pair of shoes that a mother like me will wear for the rest of my life. I will speak about my experience in this heartbreaking real-life situation through the holistic views of Te Ao Maori and the law. My daughter's name is Chanelle Te Kura Waru, she was born on the 18th of July 1995. Chanelle died from an intentional overdose she was just 21 years old. Chanelle was an articulate independent young woman and she is our only child, her father and I loved her unconditionally, to the world she was just one person, to her father and I she was our world.
In 2016/2017, 606 people committed suicide, 457 were males and 149 were females, the highest statistic age group is 20-24yrs. The highest suicide death by methods is hanging or overdose. Maori are the highest ethnic group recording 130 deaths in 2016/2017. May 10, 2017, is the day that I was labeled a victim and my daughter a statistic.
Study of the Prevalence of Food Allergens in Patients with Allergies Admitted to Mofid Children’s Hospital During 2010 to 2016
Authors: Dehghan Banadaki Fereshte , Mansouri Mahboubeh , Shekarriz-Foumani Reza 
Published: August 2018

Introduction: Allergic diseases include a wide range of symptoms such as asthma, rhinitis, urticaria, eczema, and gastrointestinal symptoms that are becoming increasingly prevalent in today’s world. Exposure to food allergens is one of the contributing factors for allergic diseases in humans. The identification of susceptibility to food allergens plays an important role in the prevention and treatment of allergic diseases.Materials and Methods: After the clinical diagnosis of allergic diseases, patients were examined using the skin prick test.The method of collecting data was observational. All data were entered in SPSS software version 21 and analyzed using descriptive and inferential statistics.Results: A total of 466 patients with a mean age of years were studied, of which 58.6% were boys and 41.4% were girls. A total of 44.2% patients had asthma, 21.7% had allergic rhinitis, 2.1% had allergic sinusitis, 1.7% had conjunctivitis, 1.1% had angioedema, 11.6% had urticaria, 19.7% had eczema, and 26.8% had gastrointestinal allergic symptoms. A total of 114 patients (24.5%) had food allergies, of which 43.9% were girls and 56.1% were boys. In terms of the age and gender of patients, no statistically significant difference was observed between different food allergens (P<.05). The most common allergens in patients under study were peanuts (7.9%), milk (7.3%), almond (6.6%), freshwater fish (6.6%), and walnuts (6.4%).Conclusion: The findings revealed that allergen prevalence in each region is influenced by its climatic conditions, people’s food habits, their racial differences, and their lifestyles.
Inovasi Birokrasi : Perspektif Analisis Hybrid Teori
Authors: Andhika Lesmana Rian 
Published: August 2018

This research attempts to illustrate, identify and disclose some relevant scientific literature findings to construct a theoretical conceptual concept of bureaucratic innovation; How conceptual theorists of other sciences can build the concept of bureaucratic innovation to achieve an understanding of bureaucratic innovation more holistically with hybrid models. The meta-theory method (the analysis of theory) is used, the literature and documents nationally and internationally are traced deductively. Results of this study reveals that hybrid theory allows the possibility that bureaucratic innovation can be elaborated from various disciplines of science. Hybrid theory model can explain various assumption that exist in bureaucracy. however, hybrid concept needs to be tested with empirical approach in order to be more coherent and constructive. Therefore, this research can be a source of limited theoretical conceptual knowledge of bureaucratic innovation outlined from some of the existing scientific literature.
Keywords: bureaucracy, innovation, hybrid model
AbstrakPenelitian ini lebih berupaya untuk mengambarkan, mengidentifikasi dan mengungkapkan beberapa temuan literatur ilmiah yang relevan untuk membangun konseptual teoritik inovasi birokrasi. Bagaimana konseptual teoretik dari ilmu pengetahuan lain dapat membangun konsep inovasi birokrasi agar mencapai pemahaman tentang inovasi birokrasi lebih holistik dengan model hybrid. Metode meta-theory (the analysis of theory) digunakan, literatur dan dokumen secara nasional dan internasional ditelusuri secara deduktif. Hasil penelitian ini mengungkapkan, inovasi birokrasi bisa dielaborasi dari berbagai disiplin ilmu pengetahuan. Model hybrid theory memungkinkan untuk itu, model ini dapat menerangkan berbagai asumsi yang ada dalam birokrasi, lebih lanjut konsep hybrid perlu diuji dengan pendekatan empiris agar lebih koheren dan konstruktif. Oleh sebab itu penelitian ini dapat menjadi sumber pengetahuan tentang konseptual teoritis inovasi birokrasi yang terbatas diuraikan dari beberapa literatur ilmiah yang ada.
Kata kunci: birokrasi, inovasi, hibrid model
Glaux maritima L. (Primulaceae), a new plant species in SE Europe
Authors: Alegro Antun , Šegota Vedran , Koletić Nikola , Vuković Nina , Vilović Tihana , Rimac Anja 
Published: August 2018

Abstract
A small population of the circumholoarctic species Glaux maritima L. (Primulaceae) was discovered in the Mediterranean part of Croatia, on the bank of the River Zrmanja. This is the first record of G. maritima in SE Europe, and the third record in the Mediterranean, apart from in Spain and the Asian part of Turkey. It was found on the open riverbank within sub-halophytic vegetation, forming a small population of several dozen erect stems, most probably clonally propagated. The site is characterized by a periodic intrusion of seawater. We propose to classify this species as critically endangered (CR) on a national level due to the small population size and the fragile habitat, which requires active protection and conservation.
Controlling beer filtration process through implementation of enzymatic and microbiological techniques
Authors: Pinguli Luljeta , Malollari Ilirjan , Troja Rozana , Manaj Hasime , Dhroso Anisa 
Published: August 2018

Abstract
The best practice for filtration optimization process is to control biological and non biological particles at every stage of beer chain production. There are several processes that can be used to control beer filtration process, such as settlement of non-biological and biological particles through sedimentation, centrifugation, extended stabilization periods, addition of flocculants and clarifiers to reduce both, yeast and haze loadings etc. Filtration process is controlled by yeast, proteins and carbohydrates. Cell yeast number in suspension determines which is going to dominate filtration process. If yeast cell number is less than a million, filterability is dependent mainly from physico-chemical beer characteristics, otherwise biological phase control filtration process. In this paper we have proposed some enzymatic and yeast management techniques to improve filtration process. Experiments were carried out in laboratory and industrial scale. There were used free and immobilized enzymes and yeast. It was noticed a good correlation between laboratory and industrial application findings. Immobilized yeast in batch processes not only make easier yeast management but also increase beer filterability, excluding some energy consuming processes like centrifugation and long conditioning time
Morphological, optical and electrochromic properties of dry-lithiated nanostructured WO3 thin films
Authors: Madhuri K.V. , Babu M. Bujji 
Published: August 2018

Abstract
Tungsten trioxide (WO3) thin films were prepared by thermal evaporation technique on thoroughly cleaned glass substrates at high pressure of 133.322 mPa in presence of argon. The substrate temperature was maintained from 6 °C to 8 °C with the help of a cold jar. The deposited films were annealed at 400 °C in air for about 2 hours. The films were characterized in terms of their composition by X-ray photoelectron spectroscopy. Subsequently, the laboratory developed dry lithiation method was used to intercalate lithium atoms into as-deposited films in various proportions. With the amount of lithium content inserted into the film, the films showed coloration in visible and near infrared regions. The morphology, coloration efficiency and optical constants of annealed and lithiated films were calculated.
Characteristics of Menstrual Disorders
Authors: Ruszkowska Hanna , Lewicka Magdalena , Sulima Magdalena , Bakalczuk Grzegorz , Taracha Anna , Wdowiak Artur 
Published: August 2018

Abstract
Introduction. The structure was based on the World Health Organisation classification. The article includes description of main causes, diagnostics and treatment of menstrual disorders. Menstrual disorder is an abnormal condition in woman’s menstrual cycle. There are disorders of ovulation, cycle length, blood flow and others. The article reviews hypogonadotropic hypogonadism, disorders of hypothalamic pituitary axis, ovarian insufficiency, congenital malformations, hyperprolactinaemia, genetic syndromes, pituitary gland tumours and unclassified disorders like premenstrual syndrome and dysmenorrhoea. Aim. Analysis of current literature with the focus on the systematisation of menstrual disorders. Conclusion. It is crucial for medical practitioners, who take care of a female patient, to have reliable knowledge of not only physiology, but also menstrual disorders. It will allow an early recognition of the symptoms, proper diagnosis and treatment in the optimal time.
Is there a cost at encoding words with joined letters during visual word recognition?
Authors: Roldán Manuel , Marcet Ana , Perea Manuel 
Published: August 2018

Abstract
For simplicity, models of visual-word recognition have focused on printed words composed of separated letters, thus overlooking the processing of cursive words. Manso de Zuniga, Humphreys, and Evett (1991) claimed that there is an early “cursive normalization” encoding stage when processing written words with joined letters. To test this claim, we conducted a lexical decision experiment in which words were presented either with separated or joined letters. To examine if the cost of letter segmentation occurs early in processing, we also manipulated a factor (i.e., word-frequency) that is posited to affect subsequent lexical processing. Results showed faster response times for the words composed of separated letters than for the words composed of joined letters. This effect occurred similarly for low- and high-frequency words. Thus, the present data offer some empirical support to Manso de Zuniga et al.’s (1991) idea of an early “cursive normalization” stage when processing joined-letters words. This pattern of data can be used to constrain the mapping of the visual input into letter and word units in future versions of models of visual word recognition.
Analysis of inclusionary housing as an urban planning instrument of the North in the South: the context of Dhaka
Authors: Nahrin Kasphia 
Published: August 2018

Abstract
Many cities in the North are adopting an inclusionary housing policy in response to housing affordability and social inclusion, which is implemented in very few cities in the South. There is a research gap to determine the potential of this planning instrument in the fast growing cities in developing countries. This research reviews the possibility of implementing inclusionary housing policies there. This is case study research, which has selected Dhaka, the capital city of Bangladesh, as a case study city. Data have been collected from both primary sources (site surveys and in-depth semi-structured interviews) and secondary sources. A qualitative thematic analysis has been performed. This research revealed that implementing inclusionary housing policy in Dhaka is currently challenging due to the lack of legal, financial and organisational capacity. However, this policy can be enabled through the revision of housing policy, the legal and institutional frameworks, financial mechanisms, the knowledge base, and finally through political will.
Measuring dynamic public transit accessibility to local centres in Warsaw
Authors: Goch Katarzyna , Ochota Szymon , Piotrkowska Monika , Kunert Zuzanna 
Published: August 2018

Abstract
Over the last decade the number of studies on public transit accessibility has significantly increased. The aim of the study was to analyse the scope of application of measurements of the dynamic time accessibility in transportation systems for evaluation purposes. It was assumed that the indicator is a feasible measure for basic analysis however additional indicators are needed for reliable assessment. The study included assessing access to the global centre of Warsaw and to local and district centres in particular units. Public transit accessibility was analysed using schedule-based travel time and the population data statistic. The results of the study confirm the dynamic character of public transit time accessibility and its usefulness as a measure. Spatial and transit barriers were identified in local distribution centres and public transit operation. The work presented in the paper highlights the relevance of the in-depth evaluation of the public transit system in relation to the major congestion problems in Warsaw.
The Rise of the “Weekend Warrior”
Authors: O'Donovan Gary , Sarmiento Olga L. , Hamer Mark 
Published: August 2018

In this Viewpoint, we celebrate sport, exercise, and the weekend warrior, the individual who performs the recommended amount of aerobic activity using 1 or 2 sessions per week. We show that the weekend warrior is thriving in the United Kingdom, the United States, and Latin America. We argue that vigorous activity and the pursuit of cardiorespiratory fitness are important to the health of the weekend warrior. Finally, we suggest that the weekend warrior physical activity pattern should be accommodated in future physical activity guidelines and interventions. J Orthop Sports Phys Ther 2018;48(8):604–606. doi:10.2519/jospt.2018.0611
Sacral Osteosarcoma Masquerading as Posterior Thigh Pain
Authors: Arumugam Ashokan 
Published: August 2018

A 36-year-old man with insidious onset of posterior right thigh pain that had started 1 month previously sought physical therapy consultation after his pain was nonresponsive to nonsteroidal anti-inflammatory drugs prescribed by his physician. Radiographs were noncontributory. Given the atypical findings during examination, the physical therapist referred him to an orthopaedic surgeon, who ordered magnetic resonance imaging that revealed a sacral tumor. Subsequently, a computed tomography-guided biopsy by a radiologist confirmed a high-grade sacral chondroblastic osteosarcoma. J Orthop Sports Phys Ther 2018;48(8):665. doi:10.2519/jospt.2018.8032