bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unicondylar knee arthroplasty in the inpatient vs. outpatient setting: Impact on process time
Authors: Zeini Ibrahim Mamdouh , Gabriel Meghan Hufstader , Liu Xinliang , Noblin Alice , Ramirez Bernardo , Kerina J. Mandume 
Published: April 2018

Objective: There is a lack of research on the impact of transitioning inpatient procedures to the outpatient setting, specifically on process time. Unicondylar knee arthroplasty (UKA) presents an opportunity for further investigation as it is already in the early stages of transitioning to the outpatient setting.Methods: This study analyzed the medical records of 1,075 patients who received UKA from a single surgeon (400 in the outpatient setting and 675 in the inpatient setting). Time in Pre-Op, surgery time, and time in post-anesthesia care unit (PACU) were recorded and compared between inpatient and outpatient settings using Ordinary Least Squares Regression models.Results: Outpatient UKAs outperformed inpatient UKAs across two out of three process time variables even after controlling for comorbidities, social history, demographics, and surgery related characteristics. Actual surgery time was no different between the two settings.Conclusions: This study demonstrated that UKA performed in the outpatient setting is associated substantial time savings preoperatively and postoperatively compared with cases performed in the inpatient setting. More research is needed to compare other outcome measures such as patient outcomes of UKA between the two settings. Implications beyond time savings should consider supply and human resources costs.
Giften aan afstammelingen en de legitieme: wil de ware legitimaris opstaan?
Authors: Brinkman R.E. , Kolkman W.D. 
Published: April 2018

Giften aan afstammelingen en de legitieme: wil de ware legitimaris opstaan?
De auteurs betogen dat indien iemand volgens de wet legitimaris is, de hem toegekomen giften onder artikel 4:67 onder d BW vallen. Ook wanneer de begiftigde verwerpt dan wel berust in zijn onterving, behoort de gift tot de legitimaire massa en staat deze bloot aan inkorting.
Systems of local drug delivery to arterial wall for prevention
of in-stent restenosis
Authors: Milewski Krzysztof , Turek Anna , Krauze Agata , Gąsior Paweł , Błachut Aleksandra , Jelonek Michał , Buszman Piotr , Jelonek Katarzyna , Dobrzyński Piotr , Kasperczyk Janusz , Wojakowski Wojciech 
Published: April 2018

New generation, drug-eluting stents used in the treatment of coronary and peripheral atherosclerotic disease (CPAD) significantly reduced restenosis and revascularization rates as well as frequency of thrombosis as compared to bare metal stents and first-generation drug eluting stents. However, despite fast development of this technology several reports have been published recently that describe cases of late and very late stent thrombosis, restenosis and neoatheroslerosis within arterial segments with previously implanted stents. For this reason many research are being conducted with the aim to design alternative methods for intra-arterial drugs delivery in order to reduce restenosis and revascularization rates, yet eliminating adverse effects mentioned above. One of possibilities is lipophilic and antiproliferative drug coated balloon technology, which offers high drug concentration in arterial tissue and restenotic effect in selected clinical situations despite the short balloon inflation time. A particularly interesting option is intra-arterial delivery of drugs with different mechanisms of action, regardless of their lipophilicity by loading them into biodegradable nanospheres. In this paper, currently used systems for local drug delivery have been described including their limitations and opportunities. In addition, we provided a brief description of the project sponsored by Polpharma Scientific Foundation, which aimed to evaluate potentials of local delivery of biodegradable nanospheres loaded with everolimus, which could be used to reduce restenosis rate after stent implantation.
Možnosti a limity axiomatizace práva
Authors: Horák Filip , Madej Martin 
Published: April 2018

Axiomatizace práva ve snaze učinit z něj logicky koherentní systém podobný matematice je již po staletí v centru pozornosti některých právních teoretiků a filosofů. Cílem tohoto článku je poskytnout preciznější vymezení klíčových pojmů, nastínit přehled dosavadního vývoje zásadních myšlenek ohledně tohoto tématu, jakož i na teoretické a metodologické rovině diskutovat o tom, zdali je axiomatizace práva jednak možná a jednak žádoucí.
Frizzled-related proteins 4 (SFRP4) rs1802073G allele predicts the elevated serum lipid levels during acitretin treatment in psoriatic patients from Hunan, China
Authors: Zhou Xingchen , Zhu Wu , Shen Minxue , He Yijing , Peng Cong , Kuang Yehong , Su Juan , Zhao Shuang , Chen Xiang , Chen Wangqing 
Published: April 2018

Background
Acitretin is a second-generation synthetic retinoid, and is widely used for treating the severe psoriasis vulgaris. However, it should be chosen with caution for its cardiovascular risk, and it is reported that acitretin may increase the serum lipids. The purpose of this study is to investigate the relationship between the Frizzled-related proteins 4 (SFRP4) rs1802073 polymorphism and the changes of serum lipids in Chinese psoriatic patients during the treatment with acitretin.

Methods
In our study, 100 psoriatic patients were recruited systematically treated with acitretin (30 mg/day) for at least eight weeks. Data of the patients’ demographic and clinical characteristics and the results of serum triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C) and low-density lipoprotein cholesterol (LDL-C) were collected pre- and post-treatment.

Results
A total of 84 psoriatic patients were enrolled and divided into three groups by SFRP4 rs1802073 genotypes. The patients who carried with TT genotype had maintained levels of TG and LDL-C after acitretin treatment, while patients with GG/GT genotypes had significantly elevated levels of serum TG and LDL-C compared to the TT genotype (ΔTG%: 27.53 ± 59.13 vs −1.47 ± 37.79, p = 0.026, ΔLDL-C%: 10.62 ± 26.57 vs −1.29 ± 17.07, p = 0.042). The association of rs1802073 with TG and LDL-C profiles remained significant after adjusting for age, gender, and body mass index. Although without significance, the pre-post change in serum level of TC across rs1802073 GG/GT genotypes demonstrated a trend similar to TG and LDL, and the serum level of HDL-C demonstrated a trend opposite to TG, TC and LDL.

Conclusions
Our results demonstrated that SFRP4 rs1802073 polymorphism was found to be associated with elevated serum lipid levels after acitretin treatment, and it may serve as a genetic marker of safe and precise treatment for individual psoriatic patients.
Magnetism at Depth: A View from an Ancient Continental Subduction and Collision Zone
Authors: McEnroe Suzanne A. , Robinson Peter , Church Nathan , Purucker Michael 
Published: April 2018

AbstractRecent sophisticated global data compilations and magnetic surveys have been used to investigate the nature of magnetization in the lower crust and upper mantle. Two approaches to constraining magnetizations are developed, providing minimum (0.01 SI) and maximum (0.04 SI) susceptibility estimates, given some assumed thickness (15+ km here). These values are higher than are found in many continental rocks. Are there rocks deeper in the crust or upper mantle that are more magnetic than expected, or are the model assumptions incomplete? What is the magnetic behavior of deep‐crustal and upper mantle rocks, when slightly cooler than the Curie or Néel temperatures of their magnetic minerals, after being exhumed from locations of high‐grade metamorphism at greater depth? Different sets of equilibrium metamorphic minerals can be considered that would form under different conditions. Results on 1,501 samples from the Western Gneiss Region (WGR) Norway, mainly from mafic and ultramafic bodies subducted to depths of 60–200 km and temperatures of 750 up to 950°C at the very highest pressures, show that rocks did not fully equilibrate to the dominant metamorphic‐facies conditions. There is a large variation in petrophysical properties, oxide minerals, and mineral assemblages in WGR samples, though they cannot explain the broad high‐amplitude (deep‐seated) anomalies measured in this region. The presence of magnetite, and exsolved titanohematite and hemoilmenite in samples, shows those magnetic phases are preserved even at eclogite‐facies conditions, in part because complete eclogite‐facies equilibrium was rarely achieved.
The Midlatitude Positive Bay Index and the Statistics of Substorm Occurrence
Authors: McPherron Robert L. , Chu Xiangning 
Published: April 2018

AbstractThe auroral breakup and expansion are essential features of a magnetospheric substorm. Negative bays beneath the aurora and positive bays at midlatitudes accompany the expansion. These effects are caused by the substorm current wedge. The negative bay strength is provided by the auroral electrojet lower (AL) index. At midlatitudes the positive bay is caused by the field‐aligned currents connected to the electrojet. The midlatitude positive bay (MPB) index measures these effects. Both AL and MPB can be used to time auroral expansion onset. This work creates lists of MPB onsets and compares them with lists from other sources including onsets derived from IMAGE and Polar spacecraft and ground all‐sky camera data. The lists show that these measurements are nearly simultaneous with satellite expansion onsets. Substorms occur most frequently during the declining phase of the solar cycle, at the equinoxes, and after the passage of a stream interface in a corotating interaction region. Both MPB and SML indices reveal three substorm phases: growth, expansion, and recovery. In addition, the MPB onset list, the SML onset list, and the IMAGE auroral onset list reveal the presence of a 45‐min and a 2 3/4‐hr quasi‐periodicity in substorm occurrence. A comparison of the various lists reveals radical difference in their waiting time distributions and relatively low levels of association between events in the lists. The results suggest that none of the lists adequately capture the complexity of substorm activity and further refinements are needed in every algorithm used for onset detection.
Docosahexaenoic acid reversed atherosclerotic changes in human endothelial cells induced by palmitic acid in vitro
Authors: Karbasforush Saeede , Nourazarian Alireza , Darabi Masoud , Rahbarghazi Reza , Khaki‐Khatibi Fatemeh , Biray Avci Çıgır , Salimi Leila , Goker Bagca Bakiye , Novin Bahador Tanaz , Rezabakhsh Aysa , Khaksar Majid 
Published: April 2018

Abnormal activity of atherosclerotic endothelial cells paving luminal surface of blood vessels has been described in many diseases. It has been reported that natural polyunsaturated fatty acids such as docosahexaenoic acid exert therapeutic effects in atherosclerotic condition. Human umbilical vein endothelial cells were treated with 1mM palmitic acid for 48 hours and exposed to 40μM docosahexaenoic acid for the next 24 hours. Real‐time polymerase chain reaction analysis was used to measure the expression of PTX3, iNOS, and eNOS. The level of nitric oxide was detected by Griess reagent. The transcription level of genes participating in coagulation and blood pressure was studied by polymerase chain reaction array. Docosahexaenoic acid improved the survival rate by reducing apoptosis rate (P < .05). Compared with that of the group given palmitic acid, attenuation of proinflammatory status was indicated by reduced interleukin‐6 (P < .05) and prostaglandin E2 levels. All genes PTX3, iNOS, and eNOS were down‐regulated after being exposed to docosahexaenoic acid. Nitric oxide contents were not changed in cells exposed to docosahexaenoic acid. Polymerase chain reaction array confirmed the reduction of LPA, PDGFβ, ITGA2, SERPINE1, and FGA after exposure to docosahexaenoic acid for 24 hours (P < .05). Docosahexaenoic acid had potential to blunt atherosclerotic changes in the modulation of genes controlling blood coagulation, pressure, and platelet function.Significance of the studyThe current experiment showed that docosahexaenoic acid could reverse atherosclerotic changes in human endothelial cells induced by palmitic acid. The increased levels of interleukin‐6 and prostaglandin E2 in atherosclerotic cells were returned to near‐to‐normal status. Gene expression analysis showed a reduced activity of genes participating in atherosclerotic endothelial cells treated by docosahexaenoic acid. The expression of genes related to cell clotting activity was also similar to that of normal cells.
Quantum dot materials for improved autostereoscopic color filter display designs
Authors: Bartmann Roland , de la Barré René , Kuhlmey Mathias 
Published: April 2018

AbstractIn previous publications, we investigated and discussed wavelength selective autostereoscopic 3D arrangements, consisting of common LCD and RGB‐color filter barriers. We determined computed advantages of wavelength selective barriers compared with conventional barriers like lenticular and parallax barriers. An experimental demonstration showed no satisfactory results using commercial displays. The broad band wavelength spectra of backlights and filter technology resulted in high crosstalk and undesirable moiré effects. Nowadays, LCDs with quantum dot materials have come into the market and compete with OLED by improved color depth and High Dynamic Range. In this paper, we describe how to improve the characteristics of autostereoscopic displays by using quantum dot materials and show the benefits of this technology in combination with novel color filter designs.
Nucleation‐controlled dual semicrystalline morphology of polyamide 11
Authors: Jariyavidyanont Katalee , Schick Christoph , Androsch René 
Published: April 2018

AbstractCrystallization of polyamide 11 at low supercooling of the melt proceeds via heterogeneous nucleation and spherulitic growth of lamellae, while at temperatures close to the glass transition homogeneous nucleation prevails, preventing spherulite formation and leading to formation of a large number of nanometer‐sized mesophase domains. It is shown that spherulitic and non‐spherulitic crystallization at low and high supercooling of the melt, respectively, can be enforced by tailoring the cooling conditions, causing a twofold semicrystalline morphology at ambient temperature. Analysis of non‐isothermal crystallization as a function of the cooling rate, using fast scanning chip calorimetry, reveals that in the case of polyamide 11 such twofold semicrystalline morphology is predicted when cooling at rates between about 20 and 200 K s−1, since then two separate crystallization events are observed. The prediction has been confirmed by preparation of films crystallized during ballistic cooling at different rates which then were analyzed regarding their structure using optical microscopy, X‐ray diffraction and calorimetry. The study is completed by discussion of implications of twofold non‐isothermal crystallization for structure evolution in polymer processing, as well as by providing information that such behavior is not only typical for polyamide 11 but also for isotactic polypropylene or poly(butylene terephthalate) as two further examples. © 2018 Society of Chemical Industry
Biomimetic gels with chemical and physical interpenetrating networks
Authors: Dobreikina Anastasia , Shklyar Tatyana , Safronov Alexander , Blyakhman Felix 
Published: April 2018

AbstractThis study aimed to create and to characterize the functional properties of gels with semi‐interpenetrating network (semi‐IPN) with focus on possible use of these composites in biomedical engineering. Polyacrylamide as a synthetic biocompatible polymer was chosen for the chemical network. The physical network comprised the gel‐forming polysaccharides xanthan gum or gellan gum. Gels were synthesized by radical polymerization of acrylamide in aqueous solutions of polysaccharides. Mechanical and electrical properties of gels with 0.2, 0.4, 0.6, 0.8 and 1.0 wt% content of polysaccharide were investigated. It was found that the inclusion of a small amount of xanthan or gellan into the polymeric network of a polyacrylamide gel significantly shifts the gel electrical potential towards the rest potential of living cells and Young's modulus towards the elasticity limits of biological soft tissues like non‐activated muscles. From the viewpoint of biomedical applications, the main advantage of the proposed composites is that the semi‐IPN structure provides a nonlinear dependence of gel tension on gel deformation, which mimics the elasticity of natural tissues. This feature opens the possibility for the promising use of the proposed gels for musculoskeletal minibioimplants or scaffolds for tissue engineering. © 2018 Society of Chemical Industry
On mathematical approaches to modelling slender liquid jets with a curved trajectory
Authors: Decent S. P. , Părău E. I. , Simmons M. J. H. , Uddin J. 
Published: April 2018

Slender liquid jets that have a curved trajectory have been examined in a range of papers using a method introduced in Wallworket al.(Proc. IUTAM Symp. on Free-Surface Flows, 2000, Kluwer;J. Fluid Mech., vol. 459, 2002, pp. 43–65) and Decentet al.(J. Engng Maths, vol. 42, 2002, pp. 265–282), for jets that emerge from an orifice on the surface of a rotating cylindrical container, successfully comparing computational results to measurements arising from laboratory experiments. Wallworket al.(2000, 2002) and Decentet al.(2002) based their analyses on the slenderness of the jet, and neglected the torsion of the centreline of the jet, which is valid since in most situations examined the torsion is zero or small. Shikhmurzaev & Sisoev (J. Fluid Mech., vol. 819, 2017, pp. 352–400) used differential geometry and incorporated the torsion. This paper shows that these two methods produce identical results at leading order when the torsion is zero or when the torsion is$O(1)$, in an asymptotic framework based upon the slenderness of the jet, and shows that the method of Wallworket al.(2000, 2002) and Decentet al.(2002) is accurate for parameters corresponding to scenarios previously examined and also when the torsion is$O(1)$. It is shown that the method of Shikhmurzaev & Sisoev (2017) should be used when the torsion is asymptotically large or when the jet is not slender.
Taxonomy of limnic Ostracoda (Crustacea) from the Quiricó Formation, Lower Cretaceous, São Francisco basin, Minas Gerais State, Southeast Brazil
Authors: Leite Amanda Moreira , Do Carmo Dermeval Aparecido , Ress Caio Bussaglia , Pessoa Murilo , Caixeta Guilherme Miranda , Denezine Matheus , Adorno Rodrigo Rodrigues , Antonietto Lucas Silveira 
Published: April 2018

AbstractThe present work presents a detailed taxonomic study on Ostracoda from the Quiricó Formation, Areado Group, São Francisco Basin, Brazil. The samples were collected from three outcrops in the Minas Gerais State: Tereza Farm (João Pinheiro Municipality), and from the banks of the São José and Quiricó creeks (Presidente Olegário Municipality). Sixteen ostracode species were recovered:Harbinia alta,Harbiniaaff.H.angulata,Harbiniaaff. H.crepata,Harbiniaaff.H.salitrensis,Harbinia symmetrica,Brasacypris fulfaroi,Brasacypris ovum,Cypridea conjugata,Cypridea hystrix,Cypridea infima,Cypridea jequiensis,Neuquenocypris(Protoneuquenocypris)antiqua,Penthesilenula martinsi,Penthesilenula pintoinew species,Alicenula longiformisnew species, andTimiriasevia sanfranciscanensisnew species. With the recovery of well-preserved specimens, it was possible to observe new characteristics inBrasacypris ovum,Cypridea conjugata,C.hystrix, andC.infima, and propose emendments to them. Additionally, three new species are described:Penthesilenula pintoin. sp.,Alicenula longiformis, n. sp., andTimiriasevia sanfranciscanensisn. sp. To date, the genusTimiriaseviahad not been recorded in strata from Brazil. Also,Darwinula martinsiis reassigned to the genusPenthesilenula. Several species herein recorded are also found in other Brazilian continental basins, as well as in African and Argentinian basins, contributing to the knowledge of Brazilian Cretaceous continental deposits.
Blood money: Harvey'sDe motu cordis(1628) as an exercise in accounting
Authors: NEUSS MICHAEL J. 
Published: April 2018

AbstractWilliam Harvey's famous quantitative argument fromDe motu cordis(1628) about the circulation of blood explained how a small amount of blood could recirculate and nourish the entire body, upending the Galenic conception of the blood's motion. This paper argues that the quantitative argument drew on the calculative and rhetorical skills of merchants, including Harvey's own brothers. Modern translations ofDe motu cordisobscure the language of accountancy that Harvey himself used. Like a merchant accounting for credits and debits, intake and output, goods and moneys, Harvey treated venous and arterial blood as essentially commensurate, quantifiable and fungible. For Harvey, the circulation (and recirculation) of blood was an arithmetical necessity. The development of Harvey's circulatory model followed shifts in the epistemic value of mercantile forms of knowledge, including accounting and arithmetic, also drawing on an Aristotelian language of reciprocity and balance that Harvey shared with mercantile advisers to the royal court. This paper places Harvey's calculations in a previously underappreciated context of economic crisis, whose debates focused largely on questions of circulation.
‘Does it threaten the status quo?’ Elite responses to British punk, 1976–1978
Authors: Street John , Worley Matthew , Wilkinson David 
Published: April 2018

AbstractThe emergence of punk in Britain (1976–1978) is recalled and documented as a moment of rebellion, one in which youth culture was seen to challenge accepted values and forms of behaviour, and to set in motion a new kind of cultural politics. In this article we do two things. First, we ask how far punk's challenge extended. Did it penetrate those political, cultural and social elites against which it set itself? And second, we reflect on the problem of recovering the history and politics of moments such as punk, and on the value of archives to such exercises in recuperation. In pursuit of both tasks, we make use of a wide range of historical sources, relying on these rather than on retrospective oral or autobiographical accounts. We set our findings against the narratives offered by both subcultural and mainstream histories of punk. We show how punk's impact on elites can be detected in the rhetoric of the popular media, and in aspects of the practice of local government and the police. Its impact on other elites (e.g. central government or the monarchy) is much harder to discern. These insights are important both for enriching our understanding of the political significance of punk and for how we approach the historical record left by popular music.