bluuebunny/crossref_metadata_2025_split huggingface dataset:
DL-CSPF: deep-learning-based cell segmentation with a physical framework for digital holographic microscopy
Authors: Li Zhuoshi , Gu Haojie , Lu Linpeng , Shen Qian , Sun Jiasong , Chen Qian , Zuo Chao 
Published: November 2024

Digital holographic microscopy
(DHM) offers label-free, full-field imaging of live-cell samples by
capturing optical path differences to produce quantitative phase
images. Accurate cell segmentation from phase images is crucial for
long-term quantitative analysis. However, complicated cellular states
(e.g., cell adhesion, proliferation, and apoptosis) and imaging
conditions (e.g., noise and magnification) pose significant
challenge to the accuracy of cell segmentation. Here, we introduce
DL-CSPF, a deep-learning-based cell segmentation method with a
physical framework designed for high-precision live-cell analysis.
DL-CSPF utilizes two neural networks for foreground-background
segmentation and cell detection, generating foreground edges and “seed
points.” These features serve as input for a marker-controlled
watershed algorithm to segment cells. By focusing on foreground edges
and “seed points”, which have lower information entropy than complete
cell contours, DL-CSPF achieves accurate segmentation with a reduced
dataset and without manual parameter tuning. We validated the
feasibility and generalization of DL-CSPF using various open-source
and DHM-collected datasets, including HeLa, pollen, and COS-7 cells.
Long-term live-cell imaging results further demonstrate that DL-CSPF
reliably characterized and quantitatively analyzed the morphological
metrics across the cellular lifecycle, rendering it a promising tool
for biomedical research.
Altered body as a source of interactional problems in the family of individuals with neurofibromatosis type 1 – A polish study
Authors: Kowal Katarzyna , Skrzypek Michał 
Published: November 2024

Background
Neurofibromatosis type 1 (NF1) is an autosomal dominant genetic disorder, whose clinical picture is dominated by visible body changes as well as numerous somatic and behavioural abnormalities.

Aim
The aim of the study was to explore the ways in which the individual experiences NF1 in everyday life, with particular emphasis on the impact of the altered body on family interactions, in addition to the personal and social identity of individuals with NF1.

Methods
A qualitative study was performed using individual in-depth interviews with 93 individuals with NF1 (median age: 36.69; range: 18 to 64; 26% males).

Results
Body changes caused by NF1 determine the specificity of social interactions in the families of the sick. The strength and direction of the impact of body changes on social interactions depends on their type (visibility, invisibility), as well as the meanings given to them. The visibility of disease lesions triggers an attitude of excessive control and stigmatization in the family, especially on the part of the mothers of individuals with NF1, and prompts a tendency to define the individual through the prism of the disease and its bodily manifestations. In turn, the lack of visibility of disease symptoms gives rise to, especially on the part of the fathers of the sick, opposing attitudes of disease denial, normalization of its symptoms and a tendency to question the disease identity of individuals with NF1. The great intensity of interactional problems concerns especially those families in which NF1 was transmitted through inheritance, and family members blame each other for the disease. This leads to repression and denial of the disease, excluding it from the scope of issues discussed in the family, which is an attempt to avoid the attribution of blame for the disease.

Conclusions
The body changes resulting from NF1 have social consequences that are of critical importance in the lives of the sick. The impact of NF1 on family interactions depends on the ways in which the disease is understood by the sick individual and his or her family members. The obtained patient-driven data constitute a convenient starting point for designing personalized interventions supporting individuals with NF1 and their families.
Frequency of physical activity during leisure time and variables related to pain and pain medication use in Spanish adults: A cross-sectional study
Authors: Denche-Zamorano Ángel , Pastor-Cisneros Raquel , Castillo-Paredes Antonio , Adsuar-Sala José Carmelo , Salas-Gómez Diana 
Published: November 2024

Background
Physical inactivity has been identified as a risk factor for pain.

Objective
The main objective was to analyze the relationships between leisure time physical activity frequency (PAF) and pain prevalence, pain level, pain impairment, daily life pain impairment, and analgesic use in Spanish adults. In addition, risk factors such as sex, body mass index, marital status and social class were assessed for these pain variables in addition to PAF.

Method
Cross-sectional study based on data from the 2014 and 2020 European Health Surveys in Spain residents. The Chi-square test was used to analyze the relationship of dependence between the variables of interest. A correlation study calculating Spearman’s rho and a multiple logistic regression were performed to assess risk factors for pain variables.

Results
20,113 and 19,196 subjects with a median age of 49 and 52 years old in 2014 and 2020 European Health Surveys, respectively, were analyzed. Dependence relationships were found between PAF and pain variables (p<0.001). The prevalence of: pain, high levels of pain, pain impairment, high level of pain impairment and use analgesic were higher in the inactive population than in the rest of the PAF levels (36.7–53%) vs (18.6–44.3%), p<0.05. Weak correlations were found between PAF and pain variables (-0.177 ≤ Rho ≤ -0.107) (p<0.001). Logistics regression show that being active or very active reduces the odds of pain, the intensity of pain and being affected in daily activities due to pain by 0.524 to 0.776 times. Likewise, being active or very active reduces the odds of taking pain medication by 0.661 to 0.755 times. Also age, low social class, being a woman, and being obese increase of odds of pain, pain affectation and use of analgesics in both surveys by 1.008 to 2.202 times.

Conclusions
Physical inactivity was related to a higher prevalence of: pain, higher levels of pain, higher pain involvement and higher analgesic use. In addition, lower social class, being female, older age, and obesity were factors for higher odds of pain, pain involvement, and analgesic use in both surveys.
Risk of severe influenza infection in women with a history of pregnancy complications: A longitudinal cohort study
Authors: Amer Amira , Ayoub Aimina , Brousseau Émilie , Auger Nathalie 
Published: November 2024

Background
Risk factors for influenza complications in women are poorly understood. We examined the association between pregnancy outcomes and risk of influenza hospitalization up to three decades later.

Methods
We analyzed a cohort of 1,421,531 pregnant women who delivered in Quebec, Canada between 1989 and 2021. Patients were followed over time beginning at the first delivery. The main exposure measures included obstetric complications such as preeclampsia, gestational diabetes, and preterm birth. The main outcome was influenza hospitalization up to 32 years later. We used adjusted Cox regression models to estimate hazard ratios (HR) and 95% confidence intervals (CI) for the association between obstetric complications and risk of influenza hospitalization following pregnancy.

Results
A total of 4,016 women were hospitalized for influenza during 32 years of follow-up. Influenza hospitalization was more frequent among women with pregnancy complications than women without complications (18.0 vs 14.1 per 100,000 person-years). Compared with no pregnancy complication, women with gestational diabetes (HR 1.48, 95% CI 1.30–1.69), preeclampsia (HR 1.45, 95% CI 1.28–1.65), placental abruption (HR 1.36, 95% CI 1.12–1.66), preterm birth (HR 1.40, 95% CI 1.27–1.55), cesarean section (HR 1.22, 95% CI 1.13–1.31), and severe maternal morbidity (HR 1.43, 95% CI 1.22–1.68) had a greater risk of influenza hospitalization later in life. These pregnancy outcomes were associated with severe influenza infections requiring critical care.

Conclusions
Women with pregnancy complications have an elevated risk of severe influenza complications later in life and have potential to benefit from seasonal vaccination to prevent influenza hospitalization.
Effectiveness of electroacupuncture and acupuncture in alleviating cold hypersensitivity in the hands and feet: A randomized controlled trial
Authors: Kwon Na-Yoen , Yu Jun-Sang , Kim Dong-Il , Kim Hyeong-Jun , Lee Dong-Nyung 
Published: November 2024

Objective
Cold hypersensitivity in the hands and feet(CHHF) is a common condition that reduces the quality of life and causes daily discomfort. The current treatments are primarily pharmacological. This study aimed to expand treatment options by comparing the efficacy of electroacupuncture (EA) and acupuncture (AC) with that of no treatment (control).

Methods
A three-group randomized controlled trial was conducted with 72 women diagnosed with cold hypersensitivity in the hands and feet, as confirmed by subjective symptoms and objective temperature differences. Participants were randomly assigned to the EA, AC, or control groups. Outcome measures included hand and feet visual analog scale (VAS) scores, temperature changes measured using a non-contact thermometer, and World Health Organization Quality of Life-BREF (WHOQOL-BREF) scores assessed at pretreatment (T0), posttreatment (T1), and follow-up (T2). Repeated measures ANOVA and 2-way mixed-model ANOVA were used to evaluate group, time, and interaction effects.

Results
Both the EA and AC groups showed significant improvements in hand and feet VAS and WHOQOL-BREF scores compared with those of the control group posttreatment (T1). Notably, the EA group demonstrated sustained benefits at follow-up (T2), with significant reductions in feet VAS scores and positive changes in several WHOQOL-BREF domains. Interaction effects between group and time were observed, indicating that the changes in the EA and AC groups were meaningfully different form those in the control group. The control group also exhibited a statistically significant reduction in the VAS scores at follow-up (T2), likely due to the natural variability of cold extremity symptoms and psychological factors.

Conclusion
This study demonstrated that EA and AC are effective in alleviating the symptoms of CHHF and enhancing the quality of life compared to no treatment. EA showed long-lasting effects than those of AC, suggesting its potential to regulate the autonomic nervous system. These findings provide a foundation for expanding non-pharmacological treatment options for CHHF and offer clinical guidance on the use of EA and AC.
Proêmio do comentário de Tomás de Aquino ao Tratado do Céu e do Mundo de Aristóteles
Authors: Pinto Maryane Stella 
Published: November 2024

Tradução
AQUINO, Tomás. In libros Aristotelis De caelo et mundo expositio. Disponível em: http://www.corpusthomisticum.org/ccm0.html.
Parágrafo Primeiro
Como o Filósofo diz no livro primeiro da Física; opinamos conhecer cada coisa quando conhecemos as causas primeiras, e os princípios primeiros até os elementos. A partir do que o Filósofo mostra manifestamente que nas ciências há um processo ordenado, conforme se procede a partir das causas primeiras e dos princípios até as causas próximas, que são os elementos constituintes da essência da coisa. E isto é razoável: de fato o processo das ciências é obra da razão, da qual é próprio ordenar; donde em toda obra da razão se descobre alguma ordem segundo a qual se procede de um a outro. E isso é patente tanto na razão prática, cuja consideração é acerca daquilo que nós fazemos quanto na razão especulativa cuja consideração é acerca daquilo que é feito por outros.
Data de registro: 14/12/2017
Data de aceite: 11/04/2018
O Filósofo e a Religião ou “entre Jerusalém e Atenas”: Leo Strauss e o Problema Teológico-Político
Authors: Mendes Elvis de Oliveira 
Published: November 2024

Resumo: O tema da religião possui lugar central no pensamento de Leo Strauss, de fato, um dos aspectos mais importantes de sua crítica da modernidade passa pela forma que a religião é tratada pelos “filósofos das luzes”. Nesse estudo, apresento o caráter cético da crítica straussiana em relação à pretensão racionalista de substituir a fé religiosa pelo primado da razão teórica. Com isso, pretendo mostrar que para Strauss, é a manutenção da tensão entre fé e razão ou “o conflito entre Jerusalém e Atenas”, que torna possível a existência de modos de vida diferentes, como resultado de disposições distintas do espírito humano, o que revela o caráter profundamente fideísta de sua crítica.
Palavras-chave: Leo Strauss; Problema Teológico-Político; Jerusalém a Atenas; Fideísmo
The Philosopher and Religion or “Between Jerusalem and Athens”: Leo Strauss and the Theological-Political Problem
Abstract: The theme of religion has a central place in the thought of Leo Strauss, in fact, one of the most important aspects of his critique of modernity is the way in which religion is treated by the “philosophers of the Enlightenment”. In this paper, I present the skeptical character of the Straussian critique in relation to the rationalist intention of substituting religious faith for the primacy of theoretical reason. With this, I intend to show that for Strauss, it is the maintenance of the tension between faith and reason or “the conflict between Jerusalem and Athens”, which makes possible the existence of different ways of life, as a result of different dispositions of the human spirit, which reveals the profoundly fideistic character of his criticism.
Keywords: Leo Strauss; Theological-Political Problem; Jerusalem and Athens; Fideism

Data de registro: 13/01/2023
Data de aceite: 06/09/2023
O argumento da Lei Natural na Teoria Política de Leo Strauss
Authors: Souza Ronaldo Tadeu 
Published: November 2024

Resumo: Este artigo tem como objetivo reconstruir as alegações de Leo Strauss sobre a lei natural. Mesmo entendendo as complexidades da teoria política desse judeu-alemão radicado nos Estados Unidos concernente às fontes filosóficas (Platão, Tucídides, Maimônides) de suas reflexões, os autores (Nietzsche, Heidegger, Schmitt) que orientaram sua formação e o contexto histórico (República de Weimar e Estados Unidos) em que viveu, considero que o núcleo substantivo-imanente, bem como as implicações políticas que daí decorrem na modernidade, das concepções straussianas estão no modo em que se defende a legitimidade (imposta) da lei natural.
Palavras-chave: Leo Strauss; Teoria Política; Lei Natural; Modernidade; Straussianismo
The Natural Law Argument in Leo Strauss's Political Theory
Abstract: This article aims to reconstruct Leo Strauss' claims about natural law. Even understanding the complexities of the political theory of this German Jew living in the United States concerning the philosophical sources (Plato, Thucydides, Maimonides) of his reflections, the authors (Nietzsche, Heidegger, Schmitt) who guided his formation and the historical context (Republic of Weimar and United States) in which he lived, I consider that the substantive-immanent core, as well as the political implications that derive from it in modernity, of Straussian conceptions are in the way in which the (imposed) legitimacy of the natural law is defended.
Keywords: Leo Strauss; Political Theory; Natural Law; Modernity; Straussianism

Data de registro: 28/02/2023
Data de aceite: 06/09/2023
Lack of adipocyte FAM20C improves whole body glucose homeostasis
Authors: Deng Liping , Huang Yanshan , Zhao Feifei , Chen Puxin , Huang Xiaohong 
Published: November 2024

AbstractFAM20C, a member of the family with sequence similarity 20, is involved in many physiological functions. Obesity, characterized by excessive accumulation of adipose tissue, has attracted more and more attention as a worldwide health problem. Here we generated adipocyte‐specific FAM20C knockout mice to investigate the role of FAM20C in adipose tissue expansion and obesity. Our results demonstrate that knockout mice are protected against high fat diet‐induced obesity, adiposity, and fatty liver disease. Additionally, knockout mice exhibited improved metabolic phenotypes, including enhanced glucose tolerance and insulin sensitivity compared with control mice. Furthermore, we observed reduced inflammatory infiltration and collagen deposition in the adipose tissues of knockout mice. Taken together, our results indicate that targeting FAM20C in adipocytes may be a promising strategy for the treatment of obesity and associated metabolic disorders.
Aristotle on Materiate Paronymy: Concerning an Apparent Inconsistency in Aristotle’s Metaphysics
Authors: Hobbs Landon 
Published: November 2024

Abstract
Aristotle offers apparently inconsistent explanations for paronymous expressions derived from matter: on the received picture, derived from Metaphysics Θ.7, such expressions are used in all and only cases of substantial change, because predicating the matter directly of a substance would be false; on the error picture, derived from Metaphysics Z.7, the same expressions are used in all and only cases of change from an unclear and nameless privation, because ordinary language users conflate such privations with matter. I propose a resolution: the received picture explains why the usage is fitting, but the error picture explains how the usage originated.
Geschlecht und digitale Transformation in Organisationen
Authors: Gerdenitsch Cornelia , Bergmann Nadja , Schneider Anke , Gaitsch Myriam , Schöggl Astrid 
Published: November 2024

ZusammenfassungDie Einführung digitaler Technologien in Organisationen verändert Arbeitspraktiken und bietet das Potenzial, geschlechtsspezifische Machtstrukturen zu verändern. Allerdings werden in der betrieblichen Praxis durch die männlich dominierte Technologieentwicklung geschlechtsspezifische Ungleichheiten häufig eher reproduziert als abgebaut. Um das transformative Potenzial zu nutzen, ist eine aktive Gestaltung digitaler Veränderungsprozesse entscheidend, unter möglichst umfassender Einbindung unterschiedlicher Beschäftigtengruppen. Partizipative Ansätze können dabei die Einbindung unterrepräsentierter Gruppen ermöglichen. Dieser Artikel präsentiert zwei Fallstudien, in welchen partizipative Ansätze erprobt wurden. Organisation A konnte durch die Digitalisierung eines Arbeitsprozesses die Produktivität zwar erheblich steigern, in einem partizipativen Workshop wurden aber die Herausforderungen für die Beschäftigten sichtbar. Machtverschiebungen zugunsten traditionell als männlich konnotierter Arbeitsbereiche und der Verlust informellen Wissens weiblicher Beschäftigter wurden sichtbar. In Organisation B wurde eine digitale Kollaborationsplattform eingeführt, die allerdings wenig genutzt wurde. Im Rahmen eines Workshops mit administrativem Personal wurde erst das Potenzial und der Wunsch nach Beteiligung dieser Gruppe bei der Einführung neuer Technologien deutlich. Auf Basis dieser beiden Fallstudien reflektieren wir die geschlechtsbezogenen partizipativen Zugänge und die angewandten Forschungspraktiken. Darauf aufbauend formulieren wir praktische Empfehlungen zur Nutzung partizipativer Methoden in einem digitalen Transformationsprozess unter Berücksichtigung geschlechtsspezifischer Aspekte.
Morphological and molecular evidence reveals three new species of Gelidium (Gelidiaceae, Rhodophyta) for the southern Mexican Tropical Pacific
Authors: Quiroz-González Nataly , Acosta-Calderón Julio A. , Ponce-Márquez Ma. Edith , Mateo-Cid Luz Elena , Rodríguez Dení 
Published: November 2024

Abstract
The genus Gelidium is a representative element of the Mexican Tropical Pacific. The recent use of molecular tools has allowed us to resolve the taxonomic problems of some species and to increase the knowledge regarding this group of red algae in the region. The present study aimed to evaluate specimens collected in the southern Mexican Tropical Pacific using molecular markers and morphological characters. Samples were collected from four locations along the coast of Oaxaca state. They were characterised morphologically and molecularly using rbcL and COI–5P. Phylogenetic analysis classified the examined specimens into three independent clades, representing taxonomic entities different from what has been described previously for the genus. With the support of morphological data and genetic distances, we propose three new species for the Mexican Tropical Pacific: Gelidium dawsonii sp. nov., Gelidium longisporophyllum sp. nov., and Gelidium rubruparvum sp. nov. Some of the distinct characteristics of these species are based on little size of G. rubruparvum, the branching pattern of G. longisporophyllum and G. dawsonii, the number of layers of medullary cells in G. dawsonii and G. rubruparvum, and the tetrasporangial sorus in G. longisporophyllum. We also highlight the relationship between Asian and Mexican species and the value of using different tools in the evaluation of the taxonomic status of the genus Gelidium.
The genitive alternation in German
Authors: Kopf Kristin , Bildhauer Felix 
Published: November 2024

AbstractThe genitive case in German is predominantly used to form noun modifiers (die Sehenswürdigkeiten[Hamburgs] ‘the sights of Hamburg’). Such genitive modifiers occur in a variety of different registers in German, and they have been claimed to be especially characteristic of non-proximal, written language. In many instances, they are interchangeable with diachronically younger prepositional phrases headed byvon, with no noticeable impact on interpretation, thus giving rise to a genuine syntactic alternation phenomenon. There is an ongoing debate in the literature as to the distribution and function of these constructions. Based on corpus data from newspapers and internet discussion forums (approximately 15,000 noun phrases), we discuss semantic and syntactic conditions that limit the scope of this alternation. We then use a mixed-effects logistic regression model to examine a number of intra- and extralinguistic factors that bear on the choice of one construction over the other. We find thatvon-modifiers are used much less frequently than genitive modifiers overall, but there are grammatical niches in which they seem to thrive and, perhaps, even spread.
Interpreter-Mediated Diplomatic Discourse Represented and Reframed in Global News: A Case Study of China’s Statement at the General Debate of the 75th Session of United Nations General Assembly
Authors: Liang Ziyin , Li Xin 
Published: November 2024

Abstract
In 2020, against the backdrop of the pandemic, climate change and the increasingly tense global situation, Chinese President Xi Jinping delivered a speech at the General Debate of the 75th Session of United Nations General Assembly (UNGA), which attracted extensive media coverage. This research employs corpus-based critical discourse analysis to explore how the Chinese original discourse was mediated by the interpreter and how the interpreter-mediated discourse was further represented and reframed by global news. The lenses of optional shifts and reframing are adopted respectively for intertextual analysis. Results indicate that the interpreter mediates the Statement through explicitation of information, reduction of information, explicitation of logic, and change of voice. Furthermore, the interpreted text and optional shifts within the text are generally well received by global news outlets. However, due to news outlets’ highly selective quotation process and the use of temporal and spatial framing and labelling strategies, the interpreted text may be reframed to construct narratives unexpected by China. This study sheds light on the dynamic process of international communication of diplomatic discourse, during which both the interpreter and global media outlets play crucial roles apart from the source speaker.