bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lean management and operational performance in health care
Authors: Alkhaldi Rasha Zuhair , Abdallah Ayman Bahjat 
Published: September 2019

Purpose
The purpose of this paper is to examine the impact of lean management (LM) on operational performance (OP) in the context of health care in Jordanian private hospitals. LM is measured using four bundles: total quality management (TQM), human resource management (HRM), just-in-time system (JIT) and total productive maintenance (TPM). The study also investigates the effects of OP dimensions on hospitals’ business performance (BP).

Design/methodology/approach
The study is based on survey data collected from 260 respondents from 25 private hospitals in Jordan. Validity and reliability analyses were performed using SPSS and Amos, and the study hypotheses were tested using structural equation modeling.

Findings
The study found that the TQM bundle affects quality performance positively, but does not affect efficiency and accessibility performances, while the HRM bundle positively affects all OP dimensions. Furthermore, the JIT bundle positively contributes to both efficiency and accessibility performances, while the TPM bundle positively influences quality and accessibility performances. Moreover, the results have demonstrated that OP dimensions of quality and accessibility significantly and positively affect hospitals’ BP.

Originality/value
This study is one of the first to adapt the four lean bundles popularized in the manufacturing sector and apply them in a health-care context. It examines the effects of the four lean bundles on hospitals’ OP in terms of efficiency, quality and accessibility. In addition, the study demonstrates the role of OP dimensions in improving private hospitals’ BP.
Development and validation of employee wellbeing scale – a formative measurement model
Authors: Khatri Puja , Gupta Pragya 
Published: September 2019

PurposeThe purpose of this paper is to conceptualize a suitable measure for the employee wellbeing construct and validate this tool in Indian workplace settings, especially with reference to IT/ITes and BFSI sectors.Design/methodology/approachThis study is descriptive and cross-sectional in nature. The literature was first reviewed to identify the underlying probable dimensions of employee wellbeing and its corresponding items. These items were then subjected to elaborate discussions with experts from industry as well as academia. The index, thus, developed was administered to collect primary data from employees working in IT/ITeS and BFSI sectors based in Delhi-NCR. PLS SEM 3 was applied as employee wellbeing was construed as a first-order reflective second-order formative construct. Thereafter, it was subjected to suitable assessments of reliability and convergent validity.FindingsThe findings reveal that employee wellbeing can be conceptualized as a construct having four dimensions namely, purpose in life (PIL), work–life balance (WLB), job wellness (JW) and physical wellness (PW). It was also revealed that all the dimensions identified in the study capture different facets of the employee wellbeing and collectively define the construct; omission of any items may lead to change in the nature of the construct. This investigation is unique as it frames the index of employee wellbeing with specifications of a formative measurement model. To the best of the authors’ knowledge, no published study so far has measured EWB as a formative construct.Originality/valueMany earlier studies have incorporated a unidimensional approach to individual wellbeing and lacked a crucial outlook of having multi-dimensional understanding of the employee wellbeing construct in the social and work context. Furthermore, this paper contributes not only to the existing body of knowledge in employee wellbeing, but also brings forth an important aspect of measurement model specification, i.e. formative measurement model by bringing the specific reasons for taking employee wellbeing as a formative concept.
Unraveling the underlying mechanisms of new product development in high-technology emerging-market multinationals
Authors: Xiao Shufeng (Simon) , Oh Kum-Sik 
Published: September 2019

PurposeAlthough extant research has provided vast knowledge on the determinants of new product development (NPD) success, prior work is generally bounded to the framework of developed economies. Thus, research dealing with NPD, specifically in the emerging-market context, is still in its infancy. The purpose of this paper is to advance our current understanding on the determinants of NPD performance of emerging-market multinationals (EMMs) by exploring how international knowledge exploration plays a part in the international NPD performance of these firms. Furthermore, it examines how such contribution is contingent on EMMs’ international networking effectiveness and environmental dynamism that draws on the “fit” concept.Design/methodology/approachTo empirically test the theoretical model, the authors draw on a sample of 179 high-technology firms from China, which is the world’s largest emerging market.FindingsResults strongly support the hypothesis that international knowledge exploration positively affects international NPD performance. The analyses of moderating effects indicate that EMMs that are more effective in networking with global network partners and experience a low level of environmental dynamism are likely to achieve better financial performance in NPD.Originality/valueThis study advances our understanding on how and under what conditions EMMs can overcome their knowledge-disadvantaged position and achieve NPD success in global markets by highlighting the important role of international knowledge exploration and possible contingencies. Thus, it contributes to the literature on EMM and innovation.
Storytelling, business analytics and big data interpretation
Authors: Boldosova Valeriia , Luoto Severi 
Published: September 2019

Purpose
The purpose of this paper is to explore the role of storytelling in data interpretation, decision-making and individual-level adoption of business analytics (BA).

Design/methodology/approach
Existing theory is extended by introducing the concept of BA data-driven storytelling and by synthesizing insights from BA, storytelling, behavioral research, linguistics, psychology and neuroscience. Using theory-building methodology, a model with propositions is introduced to demonstrate the relationship between storytelling, data interpretation quality, decision-making quality, intention to use BA and actual BA use.

Findings
BA data-driven storytelling is a narrative sensemaking heuristic positively influencing human behavior towards BA use. Organizations deliberately disseminating BA data-driven stories can improve the quality of individual data interpretation and decision-making, resulting in increased individual utilization of BA on a daily basis.

Research limitations/implications
To acquire a deeper understanding of BA data-driven storytelling in behavioral operational research (BOR), future studies should test the theoretical model of this study and focus on exploring the complexity and diversity in individual attitudes toward BA.

Practical implications
This study provides practical guidance for business practitioners who struggle with interpreting vast amounts of complex data, making data-driven decisions and incorporating BA into daily operations.

Originality/value
This cross-disciplinary study develops existing BOR, storytelling and BA literature by showing how a novel BA data-driven storytelling approach can facilitate BA adoption in organizations.
Leaf decomposition in a cool‐temperate broad‐leaved forest established on serpentine soil on Mount Oe, Japan
Authors: Sato Kai , Nakamura Ryosuke , Kajino Hirofumi , Kawai Kiyosada , Nakai Wataru , Saito Haruka , Okada Naoki 
Published: September 2019

AbstractSerpentine ecosystems are characterized by soil with high heavy metal and low nutrient content, both of which are likely to influence the rate of leaf decomposition. Here, we report how leaf chemistry and the microbial community influence the leaf decomposition rate in a serpentine ecosystem. Fresh Clethra barbinervis and Quercus serrata leaves collected from serpentine and non‐serpentine sites in cool‐temperate forests were placed at both sites for several months, after which changes in leaf mass were determined. The N concentration in the initial Q. serrata leaves from the serpentine site was lower than in those from the non‐serpentine site. The Ni concentration in the initial C. barbinervis leaves from the serpentine site was higher than in those from the non‐serpentine site. The leaves from the serpentine site decomposed slower than those from non‐serpentine sites for both species. Although we expected that serpentine soil would have a negative influence on microbial decomposers, the Q. serrata leaves placed in the serpentine site decomposed faster than those placed in the non‐serpentine site, suggesting that the serpentine soil had no adverse effect on microbial decomposers. However, microbial respiration and biomass in an in vitro experiment were not high in the leaves decomposed on serpentine soil. Future work should reveal the mechanism behind this contradiction. Our results suggest that the change of leaf quality is key to understanding the leaf decomposition rate in a serpentine ecosystem.
Human resource management–well‐being–performance research revisited: Past, present, and future
Authors: Peccei Riccardo , Van De Voorde Karina 
Published: September 2019

AbstractThe authors provide an up‐to‐date theoretically based qualitative review of research dealing with the relationship between HRM, employee well‐being, and individual/organisational performance (HRM‐WB‐IOP research). The review is based on a systematic critical analysis of all HRM‐WB‐IOP studies (N = 46) published in 13 core HRM and management journals in the 2000 to 2018 period. The authors first identify different theoretical models of the HRM‐WB‐IOP relationship, which they then use to map research in the area. The results show that mutual gains conceptualisations play a dominant role in extant HRM‐WB‐IOP research, at the expense of alternative conflicting outcomes and mutual losses models, which are also shown to receive very limited empirical support across the 46 studies. As part of this mapping exercise, the authors identify important knowledge gaps in the area and conclude by setting out a number of key recommendations for future research to address these gaps.
Museum specimens provide reliable SNP data for population genomic analysis of a widely distributed but threatened cockatoo species
Authors: Ewart Kyle M. , Johnson Rebecca N. , Ogden Rob , Joseph Leo , Frankham Greta J. , Lo Nathan 
Published: September 2019

AbstractNatural history museums harbour a plethora of biological specimens which are of potential use in population and conservation genetic studies. Although technical advancements in museum genomics have enabled genome‐wide markers to be generated from aged museum specimens, the suitability of these data for robust biological inference is not well characterized. The aim of this study was to test the utility of museum specimens in population and conservation genomics by assessing the biological and technical validity of single nucleotide polymorphism (SNP) data derived from such samples. To achieve this, we generated thousands of SNPs from 47 red‐tailed black cockatoo (Calyptorhychus banksii) traditional museum samples (i.e. samples that were not collected with the primary intent of DNA analysis) and 113 fresh tissue samples (cryopreserved liver/muscle) using a restriction site‐associated DNA marker approach (DArTseq™). Thousands of SNPs were successfully generated from most of the traditional museum samples (with a mean age of 44 years, ranging from 5 to 123 years), although 38% did not provide useful data. These SNPs exhibited higher error rates and contained significantly more missing data compared with SNPs from fresh tissue samples, likely due to considerable DNA fragmentation. However, based on simulation results, the level of genotyping error had a negligible effect on inference of population structure in this species. We did identify a bias towards low diversity SNPs in older samples that appears to compromise temporal inferences of genetic diversity. This study demonstrates the utility of a RADseq‐based method to produce reliable genome‐wide SNP data from traditional museum specimens.
RADseq as a valuable tool for plants with large genomes—A case study in cycads
Authors: Clugston James A. R. , Kenicer Gregory J. , Milne Richard , Overcast Isaac , Wilson Trevor C. , Nagalingum Nathalie S. 
Published: September 2019

AbstractFull genome sequencing of organisms with large and complex genomes is intractable and cost ineffective under most research budgets. Cycads (Cycadales) represent one of the oldest lineages of the extant seed plants and, partly due to their age, have incredibly large genomes up to ~60 Gbp. Restriction site‐associated DNA sequencing (RADseq) offers an approach to find genome‐wide informative markers and has proven to be effective with both model and nonmodel organisms. We tested the application of RADseq using ezRAD across all 10 genera of the Cycadales including an example data set of Cycas calcicola representing 72 samples from natural populations. Using previously available plastid and mitochondrial genomes as references, reads were mapped recovering plastid and mitochondrial genome regions and nuclear markers for all of the genera. De novo assembly generated up to 138,407 high‐depth clusters and up to 1,705 phylogenetically informative loci for the genera, and 4,421 loci for the example assembly of C. calcicola. The number of loci recovered by de novo assembly was lower than previous RADseq studies, yet still sufficient for downstream analysis. However, the number of markers could be increased by relaxing our assembly parameters, especially for the C. calcicola data set. Our results demonstrate the successful application of RADseq across the Cycadales to generate a large number of markers for all genomic compartments, despite the large number of plastids present in a typical plant cell. Our modified protocol was adapted to be applied to cycads and other organisms with large genomes to yield many informative genome‐wide markers.
Non‐destructive DNA extractions from fly larvae (Diptera: Muscidae) enable molecular identification of species and enhance morphological features
Authors: Martoni Francesco , Valenzuela Isabel , Blacket Mark J 
Published: September 2019

AbstractInsects preserved as reference specimens are important in a wide range of fields, including health, pest management and forensics. The aim of the present study was to test a non‐destructive DNA extraction method on samples of soft‐bodied insects, fly larvae, which are otherwise hard to identify morphologically. This not only provides DNA enabling molecular identification but also retains morphological reference specimens for samples belonging to collections and museums that cannot be destroyed. In this work, fly larvae identified as belonging to the family Muscidae were non‐destructively processed. DNA barcoding molecular identification allowed most of these specimens to be assigned to species. Furthermore, the visibility of seven important larval morphological characters – anterior and posterior spiracles, mouth hooks, cephalopharyngeal skeleton, locomotory welts, segmentation and colour – was assessed pre‐ and post‐DNA extraction. It was found that the morphology generally did not deteriorate post‐DNA extraction but actually improved through increased visibility of internal features. Therefore, this non‐destructive DNA extraction method not only allowed COI barcode sequences to be obtained, but also enabled a better morphological identification of the fly larvae retaining physical reference voucher specimens and avoiding the need for dissections.
Integrative analysis of genome‐wide association study and expression quantitative trait loci datasets identified various immune cell‐related pathways for rheumatoid arthritis
Authors: Li Ping , Wang Xi , Guo Xiong , Wen Yan , Liu Li , Liang Xiao , Du Yanan , Wu Cuiyan , Wang Sen , Zhang Feng 
Published: September 2019

AbstractRheumatoid arthritis (RA) is an autoimmune chronic disorder manifesting as warm, swollen, and painful joints. Multiple immune cells are implicated in the development of RA. Previous studies demonstrated that integrating the genetic information of genome‐wide association studies (GWAS) and expression quantitative trait loci (eQTLs) is capable of identifying new disease‐risk loci and providing novel insights into the etiology of complex human disease. In this study, we conducted an integrative pathway association analysis of RA by using GWAS summary data and five immune cell types related to eQTL datasets of RA. After combining the cell‐specific eQTLs and GWAS summary of RA and performing a pathway‐enrichment analysis, we detected a group of RA‐associated pathways with common or cell‐specific enriched in the five immune cell types. 41 pathways for B cells, 33 pathways for CD4+ T cells, 27 pathways for CD8+ T cells, 39 pathways for monocyte, and 25 pathways for natural killer cells are significant in RA, among which 48% are common pathways and 32% are cell‐specific pathways. We detected a group of RA‐associated eQTL pathways related to five different immune cell types. Our findings may provide novel insights into the pathogenesis of RA.
Risk of rebleeding, vascular events and death after gastrointestinal bleeding in anticoagulant and/or antiplatelet users
Authors: Sostres Carlos , Marcén Beatriz , Laredo Viviana , Alfaro Enrique , Ruiz Lara , Camo Patricia , Carrera‐Lasfuentes Patricia , Lanas Ángel 
Published: September 2019

SummaryBackgroundPatients with gastrointestinal bleeding during anticoagulant and/or antiplatelet therapy represent a clinical challenge.AimTo determine the risk/rates of rebleeding, vascular events and death in patients treated with antiplatelet or anticoagulant agents who developed major gastrointestinal bleedingMethodsThis was an observational cohort study of patients who developed gastrointestinal bleeding while on antiplatelet and/or anticoagulant therapy. Drug use information was collected prospectively during bleeding events. Cox proportional hazards models were used to evaluate rebleeding, vascular events and death.ResultsAmong 871 patients (mean age 78.9 ± 8.6 years), 38.9% used an anticoagulant, 52.5% used an antiplatelet and 8.6% used both; 93.1% interrupted treatment after gastrointestinal bleeding and 80.5% restarted therapy within 7.6 ± 36.4 days; 38.7% had upper gastrointestinal bleeds, 46.7% lower gastrointestinal bleeds and 14.6% gastrointestinal bleeds of unknown origin. Median follow‐up was 24.9 months (IQR: 7.0‐38.0). Resumption of both therapies was associated with a higher risk of rebleeding, lower risk of ischaemic events or death and a similar risk for upper and lower gastrointestinal events. Resumption of therapy ≤ 7 days after bleeding showed a similar pattern with no differences in death. Rebleeding rates were higher in anticoagulant vs antiplatelet patients (138.0 vs 99.0 events per 1000 patient‐years), and the bleeding location was identical in 61.8% of cases.ConclusionsResumption of anticoagulant or antiplatelet therapy after a gastrointestinal bleeding event was associated with a lower risk of vascular events and death and a higher rebleeding risk. The benefits of early reinstitution of anticoagulant/antiplatelet therapy outweigh the gastrointestinal‐related risks.
Spit it out: Monkeys disperse the unorthodox and toxic seeds of Clivia miniata (Amaryllidaceae)
Authors: Kiepiel Ian , Johnson Steven D. 
Published: September 2019

AbstractSeeds of many Amaryllidaceae are unorthodox (recalcitrant) and toxic, and cannot survive ingestion, yet are packaged in brightly colored fruits suggestive of zoochory. Seed dispersal and germination of the understory amaryllid, Clivia miniata, were investigated in KwaZulu‐Natal, South Africa. Motion‐activated cameras revealed that samango monkeys (Cercopithecus mitis labiatus) are the primary disperser of C. miniata seeds. They eat the mesocarp and, to a lesser extent, the exocarp, and spit the large (13 mm diameter) seeds whole and cleaned onto the forest floor. Most seeds were dispersed farther than 1 m from the parent. Experimental removal of the fruit pulp had a small positive effect on the rate of seed germination, but did not affect subsequent seedling growth rates. The main advantages of monkey dispersal of Clivia seeds appear to be short‐distance dispersal away from the dense foliage of clumped parent plants and occasional long‐distance dispersal through cheek‐pouching behavior.
Meat subtypes and colorectal cancer risk: A pooled analysis of 6 cohort studies in Japan
Authors: Islam Zobida , Akter Shamima , Kashino Ikuko , Mizoue Tetsuya , Sawada Norie , Mori Nagisa , Yamagiwa Yoko , Tsugane Shoichiro , Naito Mariko , Tamakoshi Akiko , Wada Keiko , Nagata Chisato , Sugawara Yumi , Tsuji Ichiro , Matsuo Keitaro , Ito Hidemi , Lin Yingsong , Kitamura Yuri , Sadakane Atsuko , Tanaka Keitaro , Shimazu Taichi , Inoue Manami ,   for the Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Published: September 2019

AbstractRed meat and processed meat have been suggested to increase risk of colorectal cancer (CRC), especially colon cancer. However, it remains unclear whether these associations differ according to meat subtypes or colon subsites. The present study addressed this issue by undertaking a pooled analysis of large population‐based cohort studies in Japan: 5 studies comprising 232 403 participants (5694 CRC cases) for analysis based on frequency of meat intake, and 2 studies comprising 123 635 participants (3550 CRC cases) for analysis based on intake quantity. Study‐specific hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using the Cox proportional hazards model and then pooled using the random effect model. Comparing the highest vs lowest quartile, beef intake was associated with an increased risk of colon cancer in women (pooled HR 1.20; 95% CI, 1.01‐1.44) and distal colon cancer (DCC) risk in men (pooled HR 1.30; 95% CI, 1.05‐1.61). Frequent intake of pork was associated with an increased risk of distal colon cancer in women (pooled HR 1.44; 95% CI, 1.10‐1.87) for “3 times/wk or more” vs “less than 1 time/wk”. Frequent intake of processed red meat was associated with an increased risk of colon cancer in women (pooled HR 1.39; 95% CI, 0.97‐2.00; P trend = .04) for “almost every day” vs “less than 1 time/wk”. No association was observed for chicken consumption. The present findings support that intake of beef, pork (women only), and processed red meat (women only) might be associated with a higher risk of colon (distal colon) cancer in Japanese.