bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact on renal resistive index of diabetes in renal transplant donors and recipients: A retrospective analysis of 1827 kidney transplant recipients
Authors: de Freminville Jean‐Baptiste , Vernier Louis‐Marie , Roumy Jérome , Patat Frédéric , Gatault Philippe , Sautenet Bénédicte , Bailly Elodie , Chevallier Eloi , Barbet Christelle , Longuet Hélène , Merieau Elodie , Baron Christophe , Buchler Matthias , Halimi Jean‐Michel 
Published: February 2019

High renal resistive index (RI) is observed in diabetes and is associated with poor patient survival, but whether it is primarily due to renal vascular resistance or systemic vascular alterations is unclear. The respective impact of kidney transplant from diabetic donors or to diabetic recipients on RI would shed some light on this issue. The objective of the study was to analyze the impact of donor and recipient diabetes on RI in order to understand the respective impact of the kidney and the vascular environment. The authors conducted a retrospective study in 1827 renal transplant recipients who received a kidney between 1985 and 2017, and had Doppler measurements at 3 months after transplant. Donor and recipient characteristics at the time of transplant and at 3 months were reviewed. Both donor diabetes and recipient diabetes were associated with RI in univariate analysis, but only recipient diabetes remained significantly associated in stepwise multivariate analyses (effect estimate on RI: +0.03 ± 0.005, P < 0.001). These findings were confirmed when RI was expressed as a binary variable using a cutoff of 0.75 (OR = 2.50 [1.77, 3.54], P < 0.001). Other determinants of RI were recipient characteristics (age, sex, systolic and diastolic blood pressure, and duration of dialysis). Donor characteristics were not associated with RI. Our results suggest that high RI observed in diabetic recipients shortly after transplant is primarily due to the new vascular environment, rather than to characteristics of the transplanted kidney. Therefore, RI reflects systemic rather than intra‐renal changes.
Systolic blood pressure increases in patients with atrial fibrillation regaining sinus rhythm after electrical cardioversion
Authors: Olbers Joakim , Jacobson Ellen , Viberg Fredrik , Witt Nils , Ljungman Petter , Rosenqvist Mårten , Östergren Jan 
Published: February 2019

Direct current (DC) cardioversion is used to convert persistent atrial fibrillation (AF) to sinus rhythm (SR), but there is limited knowledge about how blood pressure (BP) is affected by conversion to SR. We sought to evaluate how BP changed in AF patients who converted to SR, compared to patients still in AF. In this retrospective registry analysis, we included a total of 487 patients, treated with DC cardioversion for persistent AF. We obtained data regarding medical history, medication, BP, and electrocardiogram the day before and 7 days after cardioversion. Systolic BP increased by 9 (±16) mm Hg (P < 0.01) and diastolic BP decreased by 3 (±9) mm Hg (P < 0.01) after conversion to SR. In the group of patients with restored SR, there was a 40% increase in the proportion of patients with a hypertensive BP level (≥140/90 mm Hg) after DC cardioversion compared to before. Patients still in AF had no significant change in BP. Systolic BP increases and diastolic BP slightly decreases when persistent AF is converted to SR. The underlying mechanisms explaining these findings are not known, but may involve either hemodynamic changes that occur when SR is restored, an underestimation of systolic BP in AF, or a combination of both. Our findings suggest that an increased attention to BP levels after a successful cardioversion is warranted.
Shrinkage and rehydration characteristics of vacuum assisted microwave dried green bell pepper
Authors: Kumar Vivek , Devi Moirangthem Kalpana , Panda Brajesh Kumar , Shrivastava Shanker Lal 
Published: February 2019

AbstractGreen bell pepper was dried under vacuum assisted microwave (VAM) drying conditions. The effect of microwave power (100, 200, 300 W) and vacuum pressure (200, 400, 600 mmHg) were observed on shrinkage and rehydration characteristics of the sample. Shrinkage was modeled as a linear function of volume change of material and its moisture content. A model was proposed where apparent density could be evaluated as a function of product's moisture content. The sample volume in case of VAM drying shrunk by 59 to 78%, while in case of hot air drying, the shrinkage occurred up to 90%. At a given power level of 100 W, equilibrium rehydration values (Req) increased from 5.04 to 5.75 for samples dried at increasing vacuum pressure from 200 to 600 mmHg. Rehydration rate constant decreased correspondingly for samples dried at higher microwave power levels. Higher level of microwave power and vacuum pressure played significant (p < 0.01) role in producing more porous (lesser shrunken) product leading to higher diffusion (and thus better rehydrated product) of water through it. Diffusion coefficient in rehydration was calculated using Fick's second law. The values of “k” and “R2” varied from 1 × 10−3 to 6.4 × 10−3 and 0.986 to 0.999, respectively.Practical applicationsShrinkage and rehydration characteristics of dried vegetables are of utmost importance when it comes to culinary preparations, premixes, convenient foods and retention of sensory qualities. The model proposed in the present study will be helpful in evaluating shrinkage as a function of apparent density and moisture content of dried green bell pepper. Several changes such as shape, size, structure, color, bulk density, porosity, and rehydration capacity are induced due to structural alteration in green bell pepper followed by drying. This information could help in safe commercial packaging of dried products. Further, dried green bell pepper must be rehydrated to be used in preparation of foods such as soups, pizzas, stews, casseroles, and many other recipes. Outcome of the current study can also be referred and implemented while accessing the rehydration characteristics of dried and shrunken vegetables.
Plasticity versus chronicity: Stable performance on category fluency 40 years post‐onset
Authors: de Haan Edward H. F. , Seijdel Noor , Kentridge Robert W. , Heywood Charles A. 
Published: February 2019

What is the long‐term trajectory of semantic memory deficits in patients who have suffered structural brain damage? Memory is, per definition, a changing faculty. The traditional view is that after an initial recovery period, the mature human brain has little capacity to repair or reorganize. More recently, it has been suggested that the central nervous system may be more plastic with the ability to change in neural structure, connectivity, and function. The latter observations are, however, largely based on normal learning in healthy subjects. Here, we report a patient who suffered bilateral ventro‐medial damage after presumed herpes encephalitis in 1971. He was seen regularly in the eighties, and we recently had the opportunity to re‐assess his semantic memory deficits. On semantic category fluency, he showed a very clear category‐specific deficit performing better that control data on non‐living categories and significantly worse on living items. Recent testing showed that his impairments have remained unchanged for more than 40 years. We suggest cautiousness when extrapolating the concept of brain plasticity, as observed during normal learning, to plasticity in the context of structural brain damage.
Mandible strength and geometry in relation to bite force: a study in three caviomorph rodents
Authors: Buezas Guido N. , Becerra Federico , Echeverría Alejandra I. , Cisilino Adrián , Vassallo Aldo I. 
Published: February 2019

AbstractThe monophyletic group Caviomorpha constitutes the most diverse rodent clade in terms of locomotion, ecology and diet. Caviomorph species show considerable variation in cranio‐mandibular morphology that has been linked to the differences in toughness of dietary items and other behaviors, such as chisel‐tooth digging. This work assesses the structural strength of the mandible of three caviomorph species that show remarkable differences in ecology, behavior and bite force: Chinchilla lanigera (a surface‐dwelling species), Octodon degus (a semi‐fossorial species) and Ctenomys talarum (a subterranean species). Finite element (FE) models of the mandibles are used to predict the stresses they withstand during incisor biting; the results are related to in vivo bite forces and interspecific variations in the mandibular geometries. The study concludes that the mandible of C. talarum is better able to withstand strong incisor bites. Its powerful adducting musculature is consistent with the notorious lateral expansion of the angular process and the masseteric crest, and the enhanced cortical bone thickness. Although it has a relatively low bite force, the mandible of O. degus also shows a good performance for mid‐to‐strong incisor biting, in contrast to that of C. lanigera, which exhibits, from a mechanical point of view, the worst performance. The mandibles of C. talarum and O. degus appear to be better suited to withstand stronger reaction forces from incisor biting, which is consistent with their closer phylogenetic affinity and shared digging behaviors. The contrast between the low in vivo bite force of C. lanigera and the relatively high estimations that result from the models suggests that its adductor musculature could play significant roles in functions other than incisor biting.
Prognostic value of fluorine18flourodeoxyglucose positron emission tomography/computed tomography in dogs with appendicular osteosarcoma
Authors: Griffin Lynn R. , Thamm Douglas H. , Brody Ariel , Selmic Laura E. 
Published: February 2019

BackgroundFactors indicative of a negative prognosis for appendicular osteosarcoma (OSA) in dogs are visible metastatic disease, location, and size of lesion. In human medicine maximum standard uptake value (SUVmax), as measured on a fluorine18flourodeoxyglucose positron emission tomography/computed tomography (18F‐FDG PET/CT), is prognostic for survival for several tumor types.ObjectiveDetermine if SUVmaxis associated with progression‐free interval (PFI) and determination of survival in dogs with appendicular OSA.AnimalsSixty‐two dogs with untreated appendicular OSA that had been staged with18F‐FDG PET/CT.MethodsRetrospective analysis of the18F‐FDG PET/CT was performed. Dogs were excluded from the study if they did not receive definitive intent treatment for their primary OSA and adjuvant chemotherapy with carboplatin, or had visible metastatic disease on initial imaging. A region of interest (ROI) was created around the primary tumor to measure SUVmax. Univariable and multivariable Cox proportional hazards analysis was performed to evaluate for associations between variables including SUVmaxand outcome of PFI and overall survival (OS).ResultsMaximum standard uptake value of the primary tumor was significantly associated with the OS (P = .04) with adjustment for treatment type and monocyte count. The overall median survival time (OST) was 284 days (range, 39‐1293 days) with the OST of dogs having an SUVmaxof ≥7.4 of 254 days (range, 98‐428 days) and dogs with an SUVmaxof <7.4 of 680 days (range, 108‐811 days,P = .01).Conclusions and Clinical ImportanceMaximum standard uptake value as measured via18F‐FDG PET/CT is significantly associated with survival in dogs with appendicular OSA with a high SUVmaxbeing an indicator of a negative prognosis.
Baleen whales in Macaronesia: occurrence patterns revealed through a bibliographic review
Authors: Valente Raul , Correia Ana M. , Gil Ágatha , González García Laura , Sousa‐Pinto Isabel 
Published: February 2019

Abstract

Macaronesia, an oceanic area located in the Northeast Atlantic, exhibits a high topographic and oceanographic complexity that enables a rich biodiversity. So far, seven species of baleen whales have been recorded in the area. These are migratory animals that travel long distances between feeding grounds at high latitudes in summer and tropical areas for mating and breeding in winter. As baleen whales are such mobile animals, the conservation and management of their habitat is highly challenging. Hence, knowing and understanding the patterns of their distribution is fundamental. Despite the many records of baleen whales in Macaronesia, heterogeneity in research effort has resulted in scattered occurrence data that leads to an incomplete picture of their distribution in the area.

We aim to increase knowledge of distribution patterns of baleen whales, and identify research effort gaps in Macaronesia.

From a total of 14 peer‐reviewed publications, four public reports, two poster presentations, and four data bases, we gathered 1798 records in Macaronesia since 1990 for four species of baleen whale: minke whale Balaenoptera acutorostrata, fin whale Balaenoptera physalus, blue whale Balaenoptera musculus, and humpback whale Megaptera novaeangliae. Spatio‐temporal descriptive analyses and ecological modelling were carried out in order to understand occurrence patterns.

The results show a big lack of research effort and occurrence data in offshore areas and in some coastal waters, namely off the West African coast. Moreover, blue, fin, and humpback whales are sighted mainly in spring in the north of Macaronesia, while minke whale distribution is clearly different: they have a stronger presence in summer. This study highlights areas in urgent need of research effort in order to inform decision‐makers and support effective measures for the protection and conservation of baleen whales in Macaronesia.
Age of introduction of complementary feeding and overweight in adolescence and adulthood: A systematic review
Authors: Araújo Cybele Sodré , de Farias Costa Priscila Ribas , de Oliveira Queiroz Valterinda Alves , de Santana Monica Leila Portela , Miranda Emile Pereira , Pitangueira Jacqueline Costa Dias , de Assis Ana Marlucia 
Published: February 2019

AbstractRecent studies on early infant feeding suggest that the type of diet and age of starting complementary foods may have a positive correlation with overweight in adolescence and adulthood. This study aimed to systematically review the evidence on the relationship between the age of introduction of complementary feeding and excess weight in adolescence and adulthood (PROSPERO: CRD42017067764). The preferred reporting items for systematic reviews and meta‐analyses standards were used as a reference. Articles were researched on Medline via PubMed, Web of Science, Embase, Lilacs, Ovid, and Scopus, between June and December 2017. Descriptors were defined according to Medical Subject Heading. Of the 103 articles selected for complete reading, nine were included in the review. Of these, only three found an association between the age of introduction of complementary feeding and overweight. Despite these findings, the studies presented a high heterogeneity, mainly due to the difference in cut‐off points for the age of introduction of complementary feeding and the classification of overweight. We concluded that the evidence was not consistent enough to confirm the existence of the association.
Predictors of breastfeeding non‐initiation in the NICU
Authors: Gertz Brooke , DeFranco Emily 
Published: February 2019

AbstractThis study compared predictors of breastfeeding non‐initiation between infants who were and were not admitted to the NICU so that interventions can target high‐risk mothers whose infants desperately need breastmilk. This was a population‐based retrospective cohort study of singleton Ohio live births using birth certificates, 2006–2015. In babies who were and were not admitted to the NICU, a multivariable logistic regression model assessed the association between breastfeeding non‐initiation and predictors relating to the mother, neonate, and labour and delivery events while adjusting for covariables. Of 1,463,506 births, 76,855 infants were admitted to the NICU (5.8% of study population), and breastfeeding was not initiated in 39.4% of them, compared with 31.5% of infants in the newborn nursery, p < 0.001. Apart from abnormal newborn conditions, smoking during pregnancy was the most significant risk factor for not breastfeeding in the NICU (RR 1.91 [95% CI 1.82–2.02]) and newborn nursery (RR 2.10 [95% CI 2.08–2.13]), followed by socioeconomic factors and multiparity. Limited prenatal visits (≤5) were a significantly higher risk factor in the NICU (RR 1.41 [95% CI 1.34–1.49]) than in the newborn nursery (RR 1.24 [95% CI 1.22–1.26]). Intentional home birth and use of infertility treatment were associated with breastfeeding initiation. The rate of breastfeeding initiation is lower in infants admitted to the NICU than those who are not, especially among mothers with limited prenatal care. Interventions should target mothers who smoke because they are least likely to breastfeed, and their babies, who are prone to serious health conditions, could especially benefit from breastmilk.
Impact of Preoperative Diagnosis on Clinical Outcomes of Oblique Lateral Interbody Fusion for Lumbar Degenerative Disease in a Single‐institution Prospective Cohort
Authors: Chang Sam Yeol , Nam Yunjin , Lee Jeongik , Chang Bong‐Soon , Lee Choo‐Ki , Kim Hyoungmin 
Published: February 2019

ObjectivesOblique lateral interbody fusion is considered a useful surgical option for various lumbar degenerative diseases with favorable clinical results and few complications. However, clinical outcomes following oblique lateral interbody fusion stratified according to the preoperative diagnosis have not been fully evaluated in a large cohort. The purpose of the present study was to evaluate the clinical outcomes following oblique lateral interbody fusion for lumbar degenerative disease and to identify differences in outcomes when stratified according to preoperative diagnosis.MethodsAll patients receiving oblique lateral interbody fusion for lumbar degenerative diseases were included in the current study and were stratified into four diagnostic groups: (i) degenerative spondylolisthesis; (ii) spondylolytic spondylolisthesis; (iii) spinal stenosis without spondylolisthesis and instability; and (iv) deformity. Clinical outcomes were assessed using multiple patient‐reported questionnaires. Radiologic outcomes, including cage subsidence and completion of fusion, were also evaluated.ResultsOverall, 169 patients with 262 operative levels were included in the study. All clinical scoring items showed significant improvement at 1 year postoperatively for all diagnostic groups. Net and percent improvement, and a proportion of patients reaching a threshold for substantial clinical benefit were not significantly different between the diagnostic groups in all scoring items, except for lower extremity radiating pain of the deformity group. Although the deformity group had the highest overall complication rate, neurologic complications were more frequent in the spondylolytic spondylolisthesis group. The rate of complete fusion and cage subsidence for individual levels at 1 year postoperatively was 62.7% and 32.6% respectively, with no significant difference between the diagnostic groups.ConclusionsThe large single‐institution prospective cohort of the present study showed favorable clinical outcomes following oblique lateral interbody fusion for lumbar degenerative disease, even in spinal stenosis without spondylolisthesis and instability.
Greater palatine block for V2 trigeminal neuralgia: Case report
Authors: Gornitsky Mervyn , Elsaraj Sherif M. , Canie Olivia , Mohit Shrisha , Velly Ana M. , Schipper Hyman M. 
Published: February 2019

AbstractAimsThis study describes a novel nerve block directed at the maxillary (V2) division of the fifth cranial nerve as treatment for medication‐refractory trigeminal neuralgia (TN).Methods and resultsThe authors present three cases of TN treated with V2 nerve block using commonly available local anesthetics injected through the greater palatine foramen. Patients’ medications were noted before and after the procedure. Following the injection, patients were followed over time and outcome was assessed.Patients experienced rapid and long‐lasting pain relief allowing for significant reduction in antineuralgia medications. This was done with the objective of breaking the pain cycle with subsequent discontinuation or reduction of analgesic medications.ConclusionThis technique may be an effective treatment for medication‐refractory V2 TN. By interrupting the pain cycle, this renders the condition amenable to long‐term control using diminished doses of standard antineuralgia pharmaceuticals. The practical implications of the described procedure are that it is simple, safe, and well‐tolerated with few or no adverse effects. This novel technique is a diagnostic feature for the dentist to differentiate between sources of facial pain.
A Cretaceous carbonate delta drift in the Montagna della Maiella, Italy
Authors: Eberli Gregor P. , Bernoulli Daniel , Vecsei Adam , Sekti Rizky , Grasmueck Mark , Lüdmann Thomas , Anselmetti Flavio S. , Mutti Maria , Porta Giovanna Della 
Published: February 2019

AbstractThe Upper Cretaceous (Campanian–Maastrichtian) bioclastic wedge of the Orfento Formation in the Montagna della Maiella, Italy, is compared to newly discovered contourite drifts in the Maldives. Like the drift deposits in the Maldives, the Orfento Formation fills a channel and builds a Miocene delta‐shaped and mounded sedimentary body in the basin that is similar in size to the approximately 350 km2 large coarse‐grained bioclastic Miocene delta drifts in the Maldives. The composition of the bioclastic wedge of the Orfento Formation is also exclusively bioclastic debris sourced from the shallow‐water areas and reworked clasts of the Orfento Formation itself. In the near mud‐free succession, age‐diagnostic fossils are sparse. The depositional textures vary from wackestone to float‐rudstone and breccia/conglomerates, but rocks with grainstone and rudstone textures are the most common facies. In the channel, lensoid convex‐upward breccias, cross‐cutting channelized beds and thick grainstone lobes with abundant scours indicate alternating erosion and deposition from a high‐energy current. In the basin, the mounded sedimentary body contains lobes with a divergent progradational geometry. The lobes are built by decametre thick composite megabeds consisting of sigmoidal clinoforms that typically have a channelized topset, a grainy foreset and a fine‐grained bottomset with abundant irregular angular clasts. Up to 30 m thick channels filled with intraformational breccias and coarse grainstones pinch out downslope between the megabeds. In the distal portion of the wedge, stacked grainstone beds with foresets and reworked intraclasts document continuous sediment reworking and migration. The bioclastic wedge of the Orfento Formation has been variously interpreted as a succession of sea‐level controlled slope deposits, a shoaling shoreface complex, or a carbonate tidal delta. Current‐controlled delta drifts in the Maldives, however, offer a new interpretation because of their similarity in architecture and composition. These similarities include: (i) a feeder channel opening into the basin; (ii) an excavation moat at the exit of the channel; (iii) an overall mounded geometry with an apex that is in shallower water depth than the source channel; (iv) progradation of stacked lobes; (v) channels that pinch out in a basinward direction; and (vi) smaller channelized intervals that are arranged in a radial pattern. As a result, the Upper Cretaceous (Campanian–Maastrichtian) bioclastic wedge of the Orfento Formation in the Montagna della Maiella, Italy, is here interpreted as a carbonate delta drift.