bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of willingness to use health management APP for female college students: application of UTAUT model based on Fogg theory
Authors: Wang Lanying , Zhang Yinying , Li Zhihong , Pang Xinyu , Zhang Yuanyuan , Zou Mingming 
Published: November 2024

IntroductionAs the development process of medical industry informatization has entered the stage of smart healthcare, health management applications (apps) have played an important role in improving people’s health and preventing diseases, especially among female college students.MethodsThis study combines the UTAUT model and the Fogg behavioral model (FBM) as a theoretical framework to investigate the factors affecting female college students’ willingness to use health management apps. A survey was conducted with 624 female college students regarding their usage of AI health management mobile applications.ResultsThe analysis reveals that social influence (β = 0.497, p &lt; 0.001), performance expectancy (β = 0.268, p &lt; 0.001), effort expectancy (β = 0.359, p &lt; 0.001), and facilitating conditions (β = 0.603, p &lt; 0.001) positively predict attitude; social influence (β = 0.36, p &lt; 0.001) and effort expectancy (β = 0.183, p &lt; 0.001) positively predict perceived risk, while facilitating conditions negatively predict perceived risk (β = −0.108, p &lt; 0.01). Additionally, performance expectancy (β = 0.231, p &lt; 0.001), effort expectancy (β = 0.285, p &lt; 0.001), facilitating conditions (β = 0.25, p &lt; 0.01), and attitude (β = 0.291, p &lt; 0.05) positively predict an individual’s intention to use such applications, which in turn affects actual behavior (β = 0.804, p &lt; 0.001).DiscussionThis study develops a comprehensive theoretical framework to explore the psychological and social factors influencing female college students’ utilization of health management applications. The findings underscore the significant roles of social influence, performance expectancy, effort expectancy, and facilitating conditions in shaping user attitudes and intentions. These insights offer valuable guidance for formulating effective interventions to enhance the adoption of these applications.
The main predictors of well-being and productivity from a gender perspective
Authors: Martínez-Martínez Kevin , Llorens Susana , Cruz-Ortiz Valeria , Reyes-Luján Juanjo , Salanova Marisa 
Published: November 2024

IntroductionGender difference management is one of the most challenging dimensions organizations must cope with to adapt to VUCA (Volatile, Uncertain, Complex and Ambiguous) environments. The aim of this study is to identify the main drivers (i.e., most influential job resources, job demands, and organizational practices) of healthy employees and organizational outcomes assessing the differences between men and women, based on the HERO (HEalthy and Resilient Organization) Model.MethodsData were collected through the HERO-CHECK Questionnaire: job demands (e.g., quantitative overload), job (e.g., team coordination) and personal resources (e.g., emotional competence), healthy organizational practices (e.g., work-family balance practices), healthy employees (e.g., work engagement) and healthy organizational outcomes (e.g., in-role performance). The sample consisted of 2,128 professionals (70% female) from 8 organizations. Gender-based multigroup SEM was performed using R 4.1.2.ResultsResults of the multigroup SEM analysis show a good fit of the HERO model and support the existence of configural invariance among gender groups. This research shows that women perceive more resources to cope with demands, in consequence, they perceive more well-being and better job performance. Regardless of gender, coordination, horizontal trust, vertical trust, and emotional competence stand as relevant resources for achieving healthy employees and healthy organizational outcomes. However, there are gender-specific predictors of healthy employees and healthy organizational outcomes, depending on gender.DiscussionBased on these results, gender-related recommendations for promoting specific resources (e.g., autonomy in women) and preventing specific demands (e.g., mobbing in men) may be suggested in organizational contexts.
Real-world clinical determinants of alcohol dependence in outpatients with bipolar disorder: a multicenter treatment survey for bipolar disorder in psychiatric outpatient clinics with 2,392 participants
Authors: Tokumitsu Keita , Sugawara Norio , Adachi Naoto , Kubota Yukihisa , Watanabe Yoichiro , Miki Kazuhira , Azekawa Takaharu , Edagawa Koji , Katsumoto Eiichi , Hongo Seiji , Goto Eiichiro , Ueda Hitoshi , Kato Masaki , Yoshimura Reiji , Nakagawa Atsuo , Kikuchi Toshiaki , Tsuboi Takashi , Watanabe Koichiro , Yasui-Furukori Norio 
Published: November 2024

BackgroundBipolar disorder is a psychiatric disorder characterized by mood swings between manic and depressed states that causes psychosocial problems. Cognitive function deteriorates with each recurrence, making it important to maintain remission through continued treatment. Bipolar disorder often co-occurs with alcohol dependence, which is known to lead to decreased treatment adherence and increased suicide risk. However, the real-world clinical determinants of alcohol dependence in outpatients with bipolar disorder in Japan remain unclear.MethodsWe conducted an observational study targeting 2392 patients with bipolar disorder using data from the MUSUBI study, a joint project of the Japanese Association of Neuro-Psychiatric Clinics and the Japanese Society of Clinical Neuropsychopharmacology. After determining the prevalence of alcohol dependence and the sociodemographic characteristics of patients with bipolar disorder, multivariate analysis was performed to identify risk factors for alcohol comorbidity.ResultsThe prevalence of alcohol dependence among outpatients with bipolar disorder in this study was 5.7%. The prevalence was 7.6% for males and 3.1% for females. The results of the binomial logistic regression analysis revealed that bipolar I disorder, manic state, comorbidities with other psychiatric disorders, male sex, and suicidal ideation were significantly associated with alcohol dependence. Stratified analysis by gender showed that alcohol dependence was more strongly associated with the presence of suicidal ideation in women than in men.LimitationFirst, because this was an observational study with a cross-sectional design, causal relationships between factors cannot be determined. In addition, this study included outpatients in Japan but lacked information on inpatients. Therefore, it was considered necessary to conduct the study on a larger population in order to generate more robust evidence.ConclusionsWe found that outpatients with bipolar disorder, especially men, had higher rates of alcohol dependence overall than the general population in Japan. In addition, the relationship between alcohol dependence and suicidal ideation was stronger in women than in men with bipolar disorder. There was a strong association between manic states and alcohol dependence in outpatients with bipolar disorder. These results are useful to clinicians because they reinforce real-world clinical evidence for the treatment of bipolar disorder and co-occurring alcohol dependence.
Development and validation of a National Prostalgia scale to measure acceptance and desire for cultural change
Authors: Corral Sol I. , Bray Jessica R. , Jones Daniel N. , Armenta Angel D. , Zárate Michael A. 
Published: November 2024

IntroductionDemographic changes occurring throughout the world, as well as different forms of climate and social movements, are examples of the constant cultural change people experience. Many of these changes reflect broad political and existential threats. We developed and tested the concept of national prostalgia, which we define as the longing of the nation’s future. According to Cultural Inertia theory, national prostalgia is a psychological propeller that facilitates acceptance of cultural change.MethodsWe conducted two correlational studies to develop and test the construct, and the predictive, divergent, and convergent validity of national prostalgia by comparing it to two prospection scales that measure future-thinking, and a third study to experimentally test if national prostalgia can be manipulated. We hypothesized that national prostalgia would predict higher acceptance to cultural change. Change was operationalized as eco-friendly intentions, engagement of new norms created during the COVID-19 pandemic and lowering prejudiced attitudes–beyond the effect of national nostalgia, prospection, optimism, and openness to new experiences.ResultsStudy 1 demonstrated that national prostalgia was a better predictor than prospection for higher eco-friendly intentions and acceptance of new normal norms, even when controlling for national nostalgia (i.e., a psychological anchor). In study 2, national prostalgia predicted higher eco- friendly intentions and acceptance of new normal norms, even when controlling for prospection, optimism, and openness to new experiences. National prostalgia did not predict outgroup derogation or white nationalism–variables that indicate prejudice. Study 3 replicated the basic effects, but manipulations designed to influence national prostalgia did not have their predicted effects.DiscussionThus, national prostalgia is a psychological propeller that goes above and beyond the effect of prospection and we now have a reliable and valid scale to measure national prostalgia.
Innovative vaginal manipulator technique vs. traditional method for vaginal fornix deployment in robotic sacrocolpopexy
Authors: Ota Yoshiaki , Ota Kuniaki , Takahashi Toshifumi , Kawamura Shogo , Shiota Mitsuru , Shimoya Koichiro 
Published: November 2024

Introduction and hypothesisPelvic organ prolapse (POP) affects approximately 30% of middle-aged and older women, with 11%–19% requiring surgical intervention. Laparoscopic sacrocolpopexy preserves the vaginal axis and length but involves a steep learning curve and longer operation times. Robotic sacrocolpopexy (RSC) addresses these issues, offering enhanced surgical precision. This study aimed to evaluate the feasibility and effectiveness of a novel vaginal manipulator (Hoyte Sacro Tip®; Cooper Surgical, Trumbull, CT, USA) compared with the traditional spatula in RSC.MethodsThis retrospective cohort study included 88 females undergoing RSC at Kawasaki Medical School Hospital between January 2021 and December 2023. Patients were divided into two groups: spatula (n = 50) and vaginal manipulator (n = 38). Data on patient demographics, operative outcomes, and postoperative POP quantification (POP-Q) scores were collected.ResultsBaseline characteristics were similar between the groups, except for gravidity and hypertension, which were higher in the spatula group than that in the vaginal manipulator group. No significant differences were found in operative time, console time, estimated blood loss, or complication rates between the groups (p = 0.08, 0.12, 0.19, and NA, respectively). Hospital stays were shorter in the vaginal manipulator group (median 6.5 vs. 7.0 days, p = 0.03) than in the spatula group. Both groups showed improved POP-Q scores postoperatively. However, the vaginal manipulator group had significantly lower ΔC scores than that of the spatula group (6.26 ± 3.88 vs. 8.53 ± 3.25, p = 0.02).ConclusionsThe vaginal manipulator proved to be a safe and feasible alternative to the traditional spatula, with comparable perioperative outcomes and shorter hospital stays. The manipulator's design facilitated better tissue dissection, potentially improving surgical efficiency.
Dechorionated zebrafish embryos improve evaluation of nanotoxicity
Authors: Kim Rosa , Heo Yunwi , Yoon Hakwon , Park June-Woo 
Published: November 2024

IntroductionIn response to the growing need to evaluate nanomaterial (NM) toxicity and compliance with the “3Rs” principles (replacement, reduction, and refinement of animal experiments), zebrafish (Danio rerio) embryos have emerged as a promising alternative model for studies on NM toxicity. However, zebrafish embryos are surrounded by an acellular envelope, the chorion, which limits the permeability of NMs. The present study investigated the importance of dechorionated zebrafish embryos for evaluating NM toxicity.MethodsWe utilized confocal microscopy and field-emission scanning electron microscopy with energy-dispersive spectroscopy to observe the permeability of NMs into the embryonic body using 50-nm fluorescein 5 (6)-isothiocyanate-incorporated silica nanoparticles (FITC-SiO2NPs). We investigated the physiological effects of removing the chorion using pronase on zebrafish embryos. Nanotoxicity was compared depending on the presence or absence of the chorion in zebrafish embryos using the standardized method ISO/TS 22082:2020.ResultsThe FITC-SiO2NPs were adsorbed onto the embryonic chorion; the Si content was higher in the chorion than in the embryonic body and higher in the intact zebrafish embryos than in the dechorionated ones. Dechorionated zebrafish embryos exhibited no negative physiological effects. The LC50 values of several NMs were lower in dechorionated embryos than those in intact ones.ConclusionDechorionated zebrafish embryos exhibited greater sensitivity to NMs than usual. To the best of our knowledge, this is the first study to evaluate NM toxicity using a new standardized test method, ISO/TS 22082:2020, and could contribute towards the increased utility of dechorionated embryos as an alternative model for the evaluation of nanotoxicity.
The Coordinated Changes in Platelet Glycan Patterns with Blood Serotonin and Exosomes
Authors: Kilic Fusun 
Published: November 2024

The structures of glycans, specifically their terminal positions, play an important role as ligands for receptors in regulating the adhesion ability of platelets. Recent advances in our understanding of free/unbound serotonin (5-HT) in blood plasma at supraphysiological levels implicate it as one of the most profound influencers in remodeling the platelet’s surface N-glycans. Proteomic analysis of the membrane vesicles identified enzymes, specifically glycosyltransferases, only on the surface of the platelets isolated from the supraphysiological level of 5-HT-containing blood plasma. However, these enzymes can only be effective on the cell surface under certain biological conditions, such as the level of their substrates, temperature, and pH of the environment. We hypothesize that exosomes released from various cells coordinate the required criteria for the enzymatic reaction on the platelet surface. The elevated plasma 5-HT level also accelerates the release of exosomes from various cells, as reported. This review summarizes the findings from a wide range of literature and proposes mechanisms to coordinate the exosomes and plasma 5-HT in remodeling the structures of N-glycans to make platelets more prone to aggregation.
Electrophysiological mechanisms of single-neuron stimulation using a focused femtosecond laser
Authors: Segawa Yumi , Masui Kyoko , Hosokawa Chie 
Published: November 2024

Abstract
Single-cell stimulation can be effective for investigating neuronal network functions and their relationship with electrophysiological properties of single neurons. Previous studies have reported external stimulation of single neurons with low invasiveness using a focused femtosecond laser. However, laser-induced stimulation mechanisms remain unclear and require further evaluation of their electrophysiological properties. In this study, we evaluated the electrical activity of femtosecond laser-irradiated single neurons using simultaneous fluorescence Ca2+ imaging and whole-cell patch-clamp recordings. Extracellular Ca2+ influx and highly frequent action potentials were observed in target neurons after laser irradiation. Upstate membrane potentials are caused by extracellular cation influx through disrupted membranes at the focal spot. These results suggest that single neurons were stimulated by a focused femtosecond laser. The proposed method is effective in clarifying information processing in the brain at the single-cell level.
Implementasi Perdagangan Emisi Karbon dalam Rangka Perwujudan Transformasi Indonesia Emas
Authors: Ammara Naila , Trihandini Liona Indah , Syafriadi Donal 
Published: November 2024

<p><em>Perubahan iklim dunia yang diprediksi akan mengalami penurunan emisi gas rumah kaca sebesar 81,96% di tahun 2045 menjadi permasalahan yang akan dihadapi dunia internasional termasuk Indonesia. Menipisnya ketersediaan hutan sebagai salah satu penghasil oksigen di negara maju menjadi sebuah peluang bagi Indonesia untuk melakukan perdagangan emisi karbon, salah satu caranya yakni meningkatkan pemanfaatan hutan mangrove yang memiliki nilai ekonomis. Adapun metode penelitian ini adalah penelitian kualitatif dengan teknik analisis data bersifat deskriptif dengan pendekatan perundang-undangan dan kasus. Hasil pembahasan yang didapatkan antara lain: Pertama, regulasi dan konsistensi indonesia terhadap pelaksanaan perdagangan emisi karbon masih belum tercapai sehingga diperlukan komitmen yang kuat dari pemerintah untuk melakukan aksi mitigasi sebagaimana dalam pasal 3 ayat (3) Peraturan Menteri Lingkungan hidup dan kehutanan RI no 7 tahun 2023. Kedua, implikasi perdagangan emisi karbon di Indonesia terhadap Indonesia emas 2045 terbukti menguntungkan yang mana jika pendapatan negara pertahunnya naik, maka pelaksanaan perdagangan emisi karbon akan menambah profit pendapatan negara dan emisi karbon akan bisa menjadi dana cadangan atau penyuplai kekurangan dari penurunan laju pendapatan.</em></p><p><strong><em>Kata Kunci : </em></strong><em>Hutan Mangrove, Perdagangan Emisi Karbon, Sumber Pendapatan Negara.</em><em></em></p>
Amandemen Kelima UUD 1945 dalam Rangka Upaya Penguatan Bakamla RI sebagai Penegak Hukum di Laut
Authors: Sudiro Pratondo Ario Seno , Waryoto Waryoto 
Published: November 2024

<p><em>Pengendalian laut memiliki makna bahwa suatu negara memiliki supremasi terhadap wilayah lautnya. Negara mewujudkan supremasi di laut, diperlukan adanya penegakan hukum di laut melalui lembaga penegak hukum di laut. Untuk mewujudkan penegakan hukum di wilayah laut Indonesia, Badan Keamanan Laut (Bakamla) RI dibentuk. Di sisi lain, Bakamla RI belum memiliki landasan hukum yang kuat sebagai penegak hukum di laut. Setiap pembentukan hukum harus dilandasi UUD 1945 yang menempati posisi tertinggi hierarki hukum. Masalahnya adalah UUD 1945 belum memberikan akses secara nyata terhadap restrukturisasi sistem keamanan nasional termasuk penegakan hukum di laut. Hal itu menjadi dasar perlunya amandemen kelima UUD 1945 untuk memperkuat Bakamla RI sebagai lembaga penegak hukum di laut. Penelitian ini merupakan penelitian hukum normative yang dipertajam oleh teori Hans Kelsen dan Hans Naviaski. Hasil dari penelitian ini adalah presentasi dari anggota legislatif yang memiliki urgensi terhadap penegakan hukum di laut yaitu 37,27%, yang berdasarkan ketentuan perundang-undangan di Indonesia, jumlah tersebut menunjukkan bahwa amandemen kelima UUD 1945 berkaitan dengan penegakan hukum di laut dapat diagendakan pada sidang MPR.</em></p><p> <strong><em>Kata kunci</em></strong><em>: Amandemen kelima UUD 1945, Bakamla RI, Penegakan hukum di laut.</em></p>
Time Series Analysis and Optimization of the Prediction Model of Agricultural Insurance Loss Ratio
Authors: Wang Yu , Abdullah Muhammad Asraf bin , Hwang Josephine Yau Tan 
Published: November 2024

For ensuring successful financial planning to perform sustainable farming, one key sector is to provide solutions that could accurately predict the agricultural loss ratios. In China, the Henan province is considered to be an agricultural center that is primarily exposed to drastic weather fluctuations that directly impact the crop yields. This study was conducted in Henan province from January 2020 to December 2023. With the data collected from that period, the study proposes a combinatory model combining Deep Gaussian Processes with Bayesian Long Short-Term Memory (LSTM) networks. The model was trained on data encompassing weather conditions, agricultural practices, and historical insurance claims. The experimental analysis was conducted against other traditional models, including ARIMA and Support Vector Regression. The RMSE improvement of the proposed model was around 7.2% on training data and 8.2% on test data, which demonstrates enhanced predictive accuracy. The enhanced performance of the proposed model was reflected in its effectiveness in reducing log-likelihood errors across training epochs. The model had demonstrated better robustness in handling complex and multi-dimensional agricultural data.
The Best Curriculum Practices for Development of Employability Skills: Experience from Tanzania
Authors: Koboli Gabriel Milobo , Ngirwa Coletha C. , Manyengo Patrick 
Published: November 2024

Tanzania faces a significant challenge of skills mismatch, despite various initiatives to improve employability among graduates of various educational levels. Therefore, there was the need to analyse the best curriculum practices for improving employability skills among graduates of various education levels in Tanzania. The study analysed the best curriculum practices for improving the employability skills of graduates at various educational levels in Tanzania. The Framework for Employability formed the theoretical framework of the study. A mixed methods approach with a convergent design was used in the study where quantitative and qualitative data were collected from 243 respondents purposively and randomly selected. The data were statistically and thematically analysed. The study indicated that incorporating career development services, work-integrated learning, entrepreneurship education, technological pedagogy, and authentic assessment into the curriculum can significantly improve graduates' employability skills. It was also found that the practices offer practical experience, develop transferable skills, and enhance problem-solving skills. Technological pedagogy, entrepreneurial education, and authentic assessment are the best curriculum practices for improving graduates' employability. It was recommended that entrepreneurship education, technological pedagogy, and reflective assessment practices be actively promoted to enhance employability skills among graduates
Implementasi Penggunaan Media Edukasi Video Terhadap Peningkatan Pengetahuan Menggosok Gigi Yang Benar Pada Anak Pra Sekolah Melalui Edukasi Kesehatan Gigi Dan Mulut
Authors: Agustini Ni Rai Sintya , Komang Srititin Agustina Komang Srititin Agustina , Utami Ni Kadek Ayu Dwi , Bainuan Lina Darmayanti 
Published: November 2024

Masalah kesehatan gigi dan mulut merupakan permasalahan yang sering terjadi pada anak-anak. Kesehatan gigi dan mulut merupakan upaya untuk memelihara dan meningkatkan pengetahuan anak khususnya usia sekolah.Tujuan pengabdian masyarakat ini untuk meningkatkan pengetahuan tentang menggosok gigi pada anak usia sekolah. Populasi disini merupakan anak pra sekolah di PAUD NeoGenesis. Berdasarkan hasil pretest dari 33 responden memiliki pengetahuan rendah tentang cara menggosok gigi yaitu sebesar 46%. Sedangkan hasil post test, menunjukan lebih dari setengah responden memiliki tingkat pengetahuan tinggi yaitu 57%. Kesimpulan: implementasi penggunaan media edukasi video terhadap peningkatan pengetahuan menggosok gigi yang benar pada anak pra sekolah melalui edukasi kesehatan gigi dan mulut berpengaruh terhadap pengetahuan cara menggosok gigi pada anak usia sekolah.

Kata Kunci : Pengetahuan, Media Edukasi Video, Anak Pra Sekolah