bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maximum cardiac performance of Antarctic fishes that lack haemoglobin and myoglobin: exploring the effect of warming on nature’s natural knockouts
Authors: Egginton Stuart , Axelsson Michael , Crockett Elizabeth L , O’Brien Kristin M , Farrell Anthony P 
Published: October 2019

AbstractAntarctic notothenioids, some of which lack myoglobin (Mb) and/or haemoglobin (Hb), are considered extremely stenothermal, which raises conservation concerns since Polar regions are warming at unprecedented rates. Without reliable estimates of maximum cardiac output ($\dot{Q}$), it is impossible to assess their physiological scope in response to warming seas. Therefore, we compared cardiac performance of two icefish species, Chionodraco rastrospinosus (Hb−Mb+) and Chaenocephalus aceratus (Hb−Mb−), with a related notothenioid, Notothenia coriiceps (Hb+Mb+) using an in situ perfused heart preparation. The maximum $\dot{Q}$, heart rate (fH), maximum cardiac work (WC) and relative ventricular mass of N. coriiceps at 1°C were comparable to temperate-water teleosts, and acute warming to 4°C increased fH and WC, as expected. In contrast, icefish hearts accommodated a higher maximum stroke volume (VS) and maximum $\dot{Q}$ at 1°C, but their unusually large hearts had a lower fH and maximum afterload tolerance than N. coriiceps at 1°C. Furthermore, maximum VS, maximum $\dot{Q}$ and fH were all significantly higher for the Hb−Mb+ condition compared with the Hb−Mb− condition, a potential selective advantage when coping with environmental warming. Like N. coriiceps, both icefish species increased fH at 4°C. Acutely warming C. aceratus increased maximum $\dot{Q}$, while C. rastrospinosus (like N. coriiceps) held at 4°C for 1 week maintained maximum $\dot{Q}$ when tested at 4°C. These experiments involving short-term warming should be followed up with long-term acclimation studies, since the maximum cardiac performance of these three Antarctic species studied seem to be tolerant of temperatures in excess of predictions associated with global warming.
Comparative leucocyte populations between two sympatric carnivores (Nasua narica and Procyon lotor)
Authors: Rendón-Franco Emilio , López-Díaz Osvaldo , Rodríguez-Espinosa Oscar , Rojas-Serranía Nora , Rodríguez-Cabo-Mercado Roberto , Moreno-Altamirano Maria M B , Muñoz-García Claudia I , Villanueva-García Claudia , Aguilar-Setién Alvaro 
Published: October 2019

Abstract
Coatis (Nasua narica) and raccoons (Procyon lotor) potentially play an important role in zoonotic diseases because they may carry pathogens and can transmit them to humans. To date, our understanding of the immune function of these two carnivores is deficient. The aim of this study was to compare the number of leucocyte subtypes and the phagocytic capacity between the coati and the raccoon. Blood samples were collected, and leucocyte subtypes were characterized and counted by flow cytometry and microscopy, respectively. Phagocytosis was analysed by kinetic assay. Differences in leucocytes between these two species were found; the total count of neutrophils was higher in raccoons than in coatis, but lymphocytes and eosinophils were higher in coatis than in raccoons. Antigen reduction was more rapid for the coatis. However, raccoons had a higher efficient endocytic process than coatis. This study provides the basis for understanding the procyonid immune system, which informs conservation, particularly since some procyonids are imperilled.
Progression of left anterior descending artery dissection due to stent implantation for spontaneous coronary artery dissection of left circumflex artery: a case report
Authors: Matsushita Kensuke , Ristorto Jessica , Morel Olivier , Ohlmann Patrick 
Published: October 2019

Abstract

Background
Spontaneous coronary artery dissection (SCAD) is a rare disease that predominantly affects woman. Percutaneous coronary intervention (PCI) is recommended only in patients with ongoing ischaemia because it carries a high risk of procedural complications in SCAD patients.

Case summary
A 51-year-old woman was admitted to our institution owing to severe chest pain. Coronary angiography showed a diffuse narrowing and radiolucent luminal flap which runs parallel to the vessel wall in the proximal left circumflex coronary artery and SCAD was diagnosed. After PCI was undertaken, optical coherence tomography disclosed a circular haematoma at the stent distal segment and an intimal tear at the distal left main coronary artery. A conservative approach was decided owing to patient stability without evidence of ongoing ischaemia and normal coronary flow. Thirty minutes later, the patient started to complain of chest pain with the ST-segment elevation in leads I, aVL, and V2–3. Coronary angiography demonstrated a total occlusion of the second diagonal brunch and double lumen morphology at the proximal-potion of left anterior descending with TIMI2 distal flow suggesting the extension of coronary dissection. Optical coherence tomography imaging revealed that the entry door of the dissection was located where the small intimal tear was found. Percutaneous coronary intervention was successfully performed, and the patient was discharged without any complication.

Discussion
Although the underlying mechanism of recurrent SCAD remain largely unknown, our case suggests that the residual inlet of the dissection may associate with the extension of the coronary dissection.
Is College Completion Associated with Better Cognition in Later Life for People Who Are the Least, or Most, Likely to Obtain a Bachelor’s Degree?
Authors: Greenfield Emily A , Akincigil Ayse , Moorman Sara M 
Published: October 2019

AbstractObjectivesDrawing on insights from theorizing on cumulative dis/advantage (CDA), we aimed to advance understanding of educational attainment as a protective factor for later-life cognition by examining whether associations between obtaining a bachelor’s degree and later-life cognition differ according to individuals’ likelihood of completing college based on characteristics in adolescence.MethodsWe conducted a propensity score analysis with data from the Wisconsin Longitudinal Study (WLS). Measures to predict college completion were assessed prospectively in adolescence, and a global measure of later-life cognition was based on cognitive assessments at age 65.ResultsCollege completion by age 25 (vs high school only) was associated with better later-life cognition for both men and women. Among men specifically, associations were stronger for those who were less likely as adolescents to complete college.DiscussionResults indicate the utility of a CDA perspective for investigating the implications of interconnected early life risk and protective factors for later-life cognition, as well as ways in which college education can both contribute to, as well as mitigate, processes of CDA.
Structural analysis of urinary glycosaminoglycans from healthy human subjects
Authors: Han Xiaorui , Sanderson Patience , Nesheiwat Sara , Lin Lei , Yu Yanlei , Zhang Fuming , Amster I Jonathan , Linhardt Robert J 
Published: October 2019

Abstract
Urinary glycosaminoglycans (GAGs) can reflect the health condition of a human being, and the GAGs composition can be directly related to various diseases. In order to effectively utilize such information, a detailed understanding of urinary GAGs in healthy individuals can provide insight into the levels and structures of human urinary GAGs. In this study, urinary GAGs were collected and purified from healthy males and females of adults and young adults. The total creatinine-normalized urinary GAG content, molecular weight distribution and disaccharide compositions were determined. Using capillary zone electrophoresis (CZE)–mass spectrometry (MS) and CZE–MS/MS relying on negative electron transfer dissociation, the major components of healthy human urinary GAGs were determined. The structures of 10 GAG oligosaccharides representing the majority of human urinary GAGs were determined.
Brexit identities and British public opinion on China
Authors: Chow Wilfred M. , Han Enze , Li Xiaojun 
Published: October 2019

Abstract
Many studies have explored the importance of public opinion in British foreign policy decision-making, especially when it comes to the UK's relations with the United States and the European Union. Despite its importance, there is a dearth of research on public opinion about British foreign policy towards other major players in the international system, such as emerging powers like China. We have addressed this knowledge gap by conducting a public opinion survey in the UK after the Brexit referendum. Our research findings indicate that the British public at large finds China's rise disconcerting, but is also pragmatic in its understanding of how the ensuing bilateral relations should be managed. More importantly, our results show that views on China are clearly split between the two opposing Brexit identities. Those who subscribe strongly to the Leave identity, measured by their aversion to the EU and antipathy towards immigration, are also more likely to hold negative perceptions of Chinese global leadership and be more suspicious of China as a military threat. In contrast, those who espouse a Remain identity—that is, believe that Britain would be better served within the EU and with more immigrants—are more likely to prefer closer engagement with China and to have a more positive outlook overall on China's place within the global community.
Residual Effects of Termiticides on Mortality of Formosan Subterranean Termite (Isoptera: Rhinotermitidae) on Substrates Subjected to Flooding
Authors: Sapkota Rajani , Stout Michael J , Henderson Gregg 
Published: October 2019

Abstract
Concerns on efficacies of termiticides used for soil treatment to prevent Formosan subterranean termite (Coptotermes formosanus Shiraki) infestations have prompted pest control companies to suggest that retreatments are necessary after flooding of homes. Therefore, to address concerns about the efficacy of termiticides after flooding, we designed a flooding simulation experiment in the laboratory. We used four formulated termiticides containing fipronil, imidacloprid, chlorantraniliprole, or bifenthrin as active ingredients (a.i.) and two colonies of field-collected C. formosanus for this study. Evaluations of each chemical at concentrations of 1, 10, and 25 ppm in both sand and soil were conducted in the laboratory by comparing termite mortalities in no-choice bioassays after exposure to flooded (for 1 wk) and unflooded substrates. Toxicity from bifenthrin and fipronil were not affected by flooding regardless of substrate type except at the lowest concentration tested. Toxicity from chlorantraniliprole was lower in flooded sand at 1 ppm but otherwise similar among flooding treatments. In flooded soil, toxicity from chlorantraniliprole was low at 1 ppm, but unexpectedly high in flooded conditions at 10 and 25 ppm. For all concentrations of imidacloprid-treated sand, mortality of C. formosanus was reduced after a flood. However, like chlorantraniliprole, 10 and 25 ppm of imidacloprid-treated soil in flooded conditions resulted in an increased toxicity on C. formosanus. Our study supports the idea that chemicals with a higher water solubility like imidacloprid may require a home to be retreated with less water-soluble termiticides or baits after a flood.
Acetylation of ezrin regulates membrane–cytoskeleton interaction underlying CCL18-elicited cell migration
Authors: Song Xiaoyu , Wang Wanjuan , Wang Haowei , Yuan Xiao , Yang Fengrui , Zhao Lingli , Mullen McKay , Du Shihao , Zohbi Najdat , Muthusamy Saravanakumar , Cao Yalei , Jiang Jiying , Xia Peng , He Ping , Ding Mingrui , Emmett Nerimah , Ma Mingming , Wu Quan , Green Hadiyah-Nicole , Ding Xia , Wang Dongmei , Wang Fengsong , Liu Xing 
Published: October 2019

Abstract
Ezrin, a membrane–cytoskeleton linker protein, plays an essential role in cell polarity establishment, cell migration, and division. Recent studies show that ezrin phosphorylation regulates breast cancer metastasis by promoting cancer cell survivor and promotes intrahepatic metastasis via cell migration. However, it was less characterized whether there are additional post-translational modifications and/or post-translational crosstalks on ezrin underlying context-dependent breast cancer cell migration and invasion. Here we show that ezrin is acetylated by p300/CBP-associated factor (PCAF) in breast cancer cells in response to CCL18 stimulation. Ezrin physically interacts with PCAF and is a cognate substrate of PCAF. The acetylation site of ezrin was mapped by mass spectrometric analyses, and dynamic acetylation of ezrin is essential for CCL18-induced breast cancer cell migration and invasion. Mechanistically, the acetylation reduced the lipid-binding activity of ezrin to ensure a robust and dynamic cycling between the plasma membrane and cytosol in response to CCL18 stimulation. Biochemical analyses show that ezrin acetylation prevents the phosphorylation of Thr567. Using atomic force microscopic measurements, our study revealed that acetylation of ezrin induced its unfolding into a dominant structure, which prevents ezrin phosphorylation at Thr567. Thus, these results present a previously undefined mechanism by which CCL18-elicited crosstalks between the acetylation and phosphorylation on ezrin control breast cancer cell migration and invasion. This suggests that targeting PCAF signaling could be a potential therapeutic strategy for combating hyperactive ezrin-driven cancer progression.
Bombing and Mining in War: Evidence from Cambodia
Authors: Kohama Shoko , Ohtsuki Kazuto , Tominaga Yasutaka 
Published: October 2019

AbstractThis study explores the political-economic determinants of military strategy during civil war to explain the intensity of suffering that certain conflict zones and their inhabitants suffer due to aerial bombing and landmines. Adversaries seeking post-war rents consider distinct consequences of weapons use in the target society: bombing causes instantaneous destruction, whereas landmines cause persistent but fading negative externalities on human activities, such as labor. Thus, it is expected that economic rents with different characteristics are associated with the use of different types of weapons because the benefits derived from these rents after the conflict vary. By focusing on the nature of economic rents available in conflict zones, this study demonstrates that aerial bombing is more likely when the targeted territory relies economically on renewable resources and industries such as agriculture, whereas landmines are more likely to be used in territories endowed with perishable resources such as gemstones. An empirical analysis utilizing newly compiled geo-coded data on the locations of US airstrikes and landmine contamination during the Cambodian Civil War finds strong positive associations between agricultural productivity and the number of airstrikes, and between the proximity to large gem deposits and landmine contamination, holding major tactical variables constant. The results suggest that societies' economic structures have a sizable effect on the manner in which adversaries fight a war and, therefore, affect how people suffer from it.
MaGenDB: a functional genomics hub for Malvaceae plants
Authors: Wang Dehe , Fan Weiliang , Guo Xiaolong , Wu Kai , Zhou Siyu , Chen Zonggui , Li Danyang , Wang Kun , Zhu Yuxian , Zhou Yu 
Published: October 2019

Abstract
Malvaceae is a family of flowering plants containing many economically important plant species including cotton, cacao and durian. Recently, the genomes of several Malvaceae species have been decoded, and many omics data were generated for individual species. However, no integrative database of multiple species, enabling users to jointly compare and analyse relevant data, is available for Malvaceae. Thus, we developed a user-friendly database named MaGenDB (http://magen.whu.edu.cn) as a functional genomics hub for the plant community. We collected the genomes of 13 Malvaceae species, and comprehensively annotated genes from different perspectives including functional RNA/protein element, gene ontology, KEGG orthology, and gene family. We processed 374 sets of diverse omics data with the ENCODE pipelines and integrated them into a customised genome browser, and designed multiple dynamic charts to present gene/RNA/protein-level knowledge such as dynamic expression profiles and functional elements. We also implemented a smart search system for efficiently mining genes. In addition, we constructed a functional comparison system to help comparative analysis between genes on multiple features in one species or across closely related species. This database and associated tools will allow users to quickly retrieve large-scale functional information for biological discovery.
Shewanella algae Infections in United States Naval Special Warfare Trainees
Authors: Bauer Matthew J , Stone-Garza Kristi K , Croom Daniel , Andreoli Cheryl , Woodson Peter , Graf Paul C F , Maves Ryan C 
Published: October 2019

Abstract
Shewanella infections are uncommon in immunocompetent hosts. We report 6 cases of Shewanella algae infection in young, healthy Naval Special Warfare trainees in San Diego during 2 consecutive El Niño seasons, defining a unique population at risk and adding to the epidemiologic understanding of this potentially virulent organism.
Exactly solvable discrete quantum mechanical systems and multi-indexed orthogonal polynomials of the continuous Hahn and Meixner–Pollaczek types
Authors: Odake Satoru 
Published: October 2019

Abstract
We present new exactly solvable systems of the discrete quantum mechanics with pure imaginary shifts, whose physical range of coordinates is a whole real line. These systems are shape invariant and their eigenfunctions are described by the multi-indexed continuous Hahn and Meixner–Pollaczek orthogonal polynomials. The set of degrees of these multi-indexed polynomials is $\{\ell_{\mathcal{D}},\ell_{\mathcal{D}}+1,\ell_{\mathcal{D}}+2,\ldots\}$, where $\ell_{\mathcal{D}}$ is an even positive integer ($\mathcal{D}$: a multi-index set), but they form a complete set of orthogonal basis in the weighted Hilbert space.
EXPOSURE OF THE BIOGAS STATION OPERATORS WORKING WITH CONTAMINATED BIOMASS
Authors: Škrkal Jan , Možnar Radim , Kajan Miroslav , Fantínová Karin 
Published: October 2019

Abstract
The article deals with evaluation of irradiation of an operator of a 1 MW biogas station (BGS), processing silage plant biomass contaminated by 137Cs and 134Cs. External irradiation and internal irradiation by the means of aerosol particles inhalation were considered. For calculation of the external irradiation, a BGS model was created in the MCNP. The calculated total committed effective doses received by the operator during annual handling of biomass contaminated by 1 kBq per kg of 137Cs or 134Cs were 34 or 69 μSv, respectively. Three scenarios of contamination were evaluated: freshly contaminated silage after model accident, silage right after the Chernobyl accident and at the current radiation situation in the Czech Republic.
Effects of group-size-floor space allowance during the nursery phase of production on future litter size and retention of sows through three parities1
Authors: Callahan Stuart R , Cross Amanda J , DeDecker Ashley E , Lindemann Merlin D , Estienne Mark J 
Published: October 2019

Abstract
We previously reported that reduced floor space allowance caused by increasing the number of gilts per pen decreased growth and affected blood chemistry and immunology. The current objective was to determine effects of nursery group-size-floor space allowance on future litter sizes and retention in the breeding herd through three parities in sows. A 3 × 3 factorial arrangement of treatments was employed with 2,537 gilts classified as large (6.92 ± 0.06 kg), medium (5.60 ± 0.06 kg), or small (4.42 ± 0.06 kg), and placed in nursery pens of 14, 11, or 8 pigs to allow 0.15, 0.19, or 0.27 m2 floor space/pig, respectively. After the nursery and grow-finish periods, 1,453 gilts selected for breeding were relocated to one of 11 sow farms. Total litter size and pigs born alive increased (P &lt; 0.01) with increasing parity and total litter size was 12.94, 13.28, and 13.99 (SE = 0.13) and pigs born alive was 12.21, 12.64, and 13.23 (SE = 0.11) for Parities 1, 2, and 3, respectively. There was a tendency (P = 0.08) for a quadratic relationship of group-size-floor space allowance and total litter size (13.39, 13.54, and 13.27 [SE = 0.13] for gilts allowed 0.15, 0.19, or 0.27 m2 floor space/pig, respectively). A linear effect of size of pig at weaning (P = 0.03) on pigs born dead was detected and was 0.64, 0.75, and 0.75, for small, medium, and large size pigs, respectively. There was no effect of group-size-floor space allowance on the percentages of gilts completing zero (P = 0.36), one (P = 0.35), two (P = 0.32), or three (P = 0.50) parities. In contrast, the percentage of small gilts that failed to complete one parity was greater (P &lt; 0.05) and the percentage completing one parity (P &lt; 0.05) was less than for either large or medium gilts. Abortion rate was greater (P &lt; 0.01) in gilts classified as small (2.51%) or medium (1.36%) at weaning compared with those classified as large (0.20%). Size at weaning did not affect the proportion of gilts completing two (P = 0.88) or three (P = 0.72) parities. Group-size-floor space allowance during the nursery phase of production did not have remarkable effects on future litter sizes or retention in sows. Likewise, size of pig at weaning did not affect litter size and pigs born alive. Compared with larger pigs, however, more pigs classified as small at weaning and entering the breeding herd did not complete a parity and displayed a greater abortion rate.
Pingu virus: A new picornavirus in penguins from Antarctica
Authors: de Souza William Marciel , Fumagalli Marcílio Jorge , Martin Matheus Cavalheiro , de Araujo Jansen , Orsi Maria Angela , Sanfilippo Luiz Francisco , Modha Sejal , Durigon Edison Luiz , Proença-Módena José Luiz , Arns Clarice Weis , Murcia Pablo Ramiro , Figueiredo Luiz Tadeu Moraes 
Published: October 2019

Abstract
Picornaviridae family comprises single-stranded, positive-sense RNA viruses distributed into forty-seven genera. Picornaviruses have a broad host range and geographic distribution in all continents. In this study, we applied a high-throughput sequencing approach to examine the presence of picornaviruses in penguins from King George Island, Antarctica. We discovered and characterized a novel picornavirus from cloacal swab samples of gentoo penguins (Pygoscelis papua), which we tentatively named Pingu virus. Also, using RT-PCR we detected this virus in 12.9 per cent of cloacal swabs derived from P. papua, but not in samples from adélie penguins (Pygoscelis adeliae) or chinstrap penguins (Pygoscelis antarcticus). Attempts to isolate the virus in a chicken cell line and in embryonated chicken eggs were unsuccessful. Our results expand the viral diversity, host range, and geographical distribution of the Picornaviridae.
Free Primary Education, Fertility, and Women’s Access to the Labor Market: Evidence from Ethiopia
Authors: Chicoine Luke 
Published: October 2019

Abstract
This article investigates the causal relationship between women’s schooling and fertility by exploiting variation generated by the removal of school fees in Ethiopia. The increase in schooling caused by the reform is identified using both geographic variation in the intensity of its impact and temporal variation generated by the timing of the implementation. The model finds that the removal of school fees led to an increase in schooling for Ethiopian women and that each additional year of schooling led to a reduction in fertility. An investigation of the underlying mechanisms linking schooling and fertility finds that the decline in fertility is associated with an increase in labor market opportunity and a reduction in women’s ideal number of children.