bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of a quantitative method to evaluate the wear resistance of glazed tiles
Authors: Yu Yougen , Su Huazhi , Xiao Jinghong , Yuan Fangli , Gu Xuan , Peng Cheng , Wu Jianqing 
Published: August 2019

AbstractAs glazes are papery, there is no method capable of evaluating the surface wear resistance of glazed tiles. Thus, Taber abraser with rubber wheels and abrasive belts was employed to grind out a regular wear track. The volume of track was estimated using profilometer and its analyzing software precisely. The evaluation reliability of this method was verified using six float glasses, and the standard deviation of volume loss results could be controlled less than 10%. The appropriate operating parameters were investigated using float glasses and two types of ceramic tiles from different manufacturers. The method proposed in this work has potential of success to evaluate the surface wear resistance of ceramic tiles quantitatively and precisely.
Towards potato protein utilisation: insights into separation, functionality and bioactivity of patatin
Authors: Fu Yu , Liu Wan‐Ning , Soladoye Olugbenga P. 
Published: August 2019

SummaryPotato fruit juice (PFJ) is a dilute industrial by‐product of potato starch industry containing potato protein that is abundant in patatin, a major storage protein. From an economic standpoint, conversion of potato protein into a high value‐added food ingredient has received considerable attention. In this review, the structural and physicochemical characteristics of patatin are introduced. The separation and purification methods of patatin are compared and summarised. The functional properties of patatin as food ingredients are comprehensively reviewed. The beneficial effects of patatin on health and food application are emphatically presented. In addition, the current challenges for development of patatin as a functional food ingredient are also discussed. This review offers a theoretical basis for further application of patain in the food industry.
Comparative efficacy of actinidin from green and gold kiwi fruit extract on in vitro simulated protein digestion of beef Semitendinosus and its myofibrillar protein fraction
Authors: Gong Xi , Morton James D. , Bhat Zuhaib F. , Mason Susan L. , Bekhit Alaa El‐Din A. 
Published: August 2019

SummaryThis study was conducted to evaluate the comparative efficacy of actinidin from green and gold kiwifruit extract on in vitro simulated gastrointestinal protein digestion of cooked beef Semitendinosus and its myofibrillar protein fraction. Samples collected during gastrointestinal digestion were analysed for protein profile, protein digestibility (%), soluble protein (%) and free amino acid analysis. The addition of kiwifruit extracts significantly (P < 0.05) increased protein digestibility, soluble protein and free amino acids released during in vitro gastrointestinal digestion. The in vitro digestibility (%) of the meat samples digested along the green or the gold kiwifruit extract was 2.08% and 3.47% higher than control samples respectively. The soluble protein (%) of the meat samples digested along the green kiwifruit extract was significantly (P < 0.05) higher (18.28%) than control samples (13.03%) after gastrointestinal digestion. Comparatively, actinidin from green kiwifruit extract was more effective than gold kiwifruit extract.
Keynes's grandchildren and Marx's gig workers: Why human labour still matters
Authors: EKBIA Hamid R. , NARDI Bonnie A. 
Published: August 2019

AbstractThe current anxiety around the globe regarding automation and “the future of work”, the irrelevance of human labour and the superfluity of humans is based on recurring ideas about technology, work and economic value. Not quite novel, the debate on these ideas dates back to prominent thinkers, such as Karl Marx and John Maynard Keynes. To grasp the present moment, therefore, the authors revisit this debate within the broader history of capitalism. With a focus on labour and technology, they bring attention to the hidden forms of value creation in the current economy and to the blind spots of the historical debate, and envision various possible scenarios for the future.
Predictors for influenza vaccination among Thai pregnant woman: The role of physicians in increasing vaccine uptake
Authors: Kaoiean Surasak , Kittikraisak Wanitchaya , Suntarattiwong Piyarat , Ditsungnoen Darunee , Phadungkiatwatana Podjanee , Srisantiroj Nattinee , Asavapiriyanont Suvanna , Chotpitayasunondh Tawee , Dawood Fatimah S. , Lindblade Kim A. 
Published: August 2019

AbstractBackgroundPhysician recommendation and attitudes and beliefs of pregnant women toward influenza and vaccination may influence vaccine uptake during pregnancy. We examined how physician recommendation and health beliefs of pregnant women may jointly affect influenza vaccination during pregnancy.MethodsThai pregnant women aged ≥18 years and >13 gestational weeks attending antenatal care (ANC) clinics, and ANC physicians were recruited during May‐August 2015. Women and physicians, linked using unique identifiers, provided data on demographic, health and work history, knowledge, attitudes, and beliefs toward influenza and vaccination, based on Health Belief Model constructs. Physicians also provided data on their practices in recommending influenza vaccination during pregnancy. Prevalence ratios for the association between knowledge, attitudes and beliefs of pregnant women, physician recommendation and documented receipt of vaccination within 30 days of the visit were calculated.ResultsAmong 610 women, the median age was 27 years; 266 (44%) and 344 (56%) were in the second and third trimesters, respectively. Twenty‐one (3%) had pre‐existing conditions. Of 60 physicians with the median years of practice of 5; 17 (28%) reported frequently/usually/always recommending influenza vaccine to their pregnant patients, while 43 (72%) reported never/rarely/sometimes recommending the vaccine. Controlling for the pregnant women's knowledge and beliefs, pregnant women whose physician recommended influenza vaccination were 2.3 times (95% confidence interval 1.4‐3.8) more likely to get vaccinated.ConclusionsIn this study, physician recommendation was the only significant factor associated with influenza vaccine uptake among Thai pregnant women. Understanding physicians’ motivation/barrier to recommending influenza vaccination to pregnant women may increase coverage.
Influences of supply chain finance on the mass customization program: risk attitudes and cash flow shortage
Authors: Guo Shu , Liu Na 
Published: August 2019

AbstractIn recent years, to satisfy diversified customer needs in the target market, an increasing number of brands have launched mass customization (MC) programs as one of their core operations strategies. The production process flexibility and personalization degree of customized products (i.e., the MC products) have thus become key to the success of MC schemes. In the meantime, however, considering the high market uncertainty in consumer preferences and the challenges from the production process, there are plenty of risks in MC operations. Hence, in this paper we develop a game‐theoretic model consisting of an MC brand and an upstream manufacturer to identify the influences of supply chain finance (SCF) on MC programs. The influences brought by the risk attitudes of both MC brand and manufacturer are analyzed. Besides, an extra interest rate for raising the working capital for production (e.g., from the bank) at the manufacturing level is also considered in this paper to address the impact of cash flow shortage. We find that when the positive sensitivity of the market demand with respect to the modularity level of the MC product is sufficiently high, the optimal product modularity level of the MC product increases with the MC brand's degree of risk averse. In addition, it can also be observed that when both the market demand's positive sensitivity to the modularity level of the MC product and the MC brand's opportunity cost rate for placing the advance order are sufficiently high, any increase in the risk‐averse degree of the MC brand or the manufacturer will lower the manufacturer's optimal wholesale price of the MC product as well as the MC brand's optimal rate of the advance order. Furthermore, the higher the interest that the manufacturer needs to pay (such as to the bank) for raising the working capital for the MC production process, the lower the optimal wholesale price of each finished MC product will be to help the manufacturer raise more money through the advance order placed by the MC brand. These observations complete the findings in the extant literature and provide important managerial insights into managing MC operations.
Vibrational spectroscopic and crystal chemical analyses of double perovskite Y2MgTiO6 microwave dielectric ceramics
Authors: Yang Hongcheng , Zhang Shuren , Yang Hongyu , Yuan Ying , Li Enzhu 
Published: August 2019

AbstractStructure‐property relationships of Y2MgTiO6, a type of double perovskite materials, were investigated systematically. Rietveld refinement of XRD patterns confirmed that Y2MgTiO6 belongs to the P21/c space group and has a structure analogous to that of monoclinic Dy2MgTiO6. In accordance with the observed number of vibrational bands and group theoretical predictions, O and Y ions at the 4e site dominated the Raman peaks. The IR reflectivity spectrum indicated that the major contributions to the relative permittivity and intrinsic loss were modes lower than 500 cm−1. The measured relative permittivity closely approached the calculated values determined according to P‐V‐L theory, the Clausius‐Mossotti equation and IR fitted results. The larger bond energy for Mg–O bonds than for Ti–O bonds corresponds to a more stable octahedron of [MgO6], as verified by the octahedral distortion. Satisfactory microwave dielectric properties of Y2MgTiO6 ceramics were as follows: εr = 20.4 ± 0.8, Q × f = 42 060 ± 310 GHz, τf = −52 ± 3 ppm/°C, sintered at 1450°C.
Vacancy‐ and doping‐dependent electronic and magnetic properties of monolayer SnS2
Authors: Ullah Hamid , Noor‐A‐Alam Mohammad , Shin Young‐Han 
Published: August 2019

AbstractWe have performed first‐principles calculations to investigate the formation and migration of vacancies and doping with M (M = Ti, V, Co, Mo, W, Re) at the Sn sites and X (X = O, Se, Te) at the S sites in monolayer SnS2. We find that the formation energies for S vacancy under both Sn‐ and S‐rich environments are lower than those for Sn vacancy, indicating that the vacancies at the S sites are likely to be formed during the synthesis. Reducing the possibility of vacancy cluster formation, both the vacancies at the Sn and S sites remain robust due to high migration barrier. Additionally, SnS2 with the vacancies at the Sn sites induces magnetic ground states with a magnetic moment of 4.00 μB. Both the Sn‐ and S‐sites vacancies preserve the semiconducting nature of pristine SnS2 with band gaps of 2.47 eV and 0.30 eV, respectively. Furthermore, we find that the dopants Ti, V, Mo, W, Re can be easily incorporated at the Sn sites in monolayer SnS2 due to the low formation energies under the S‐rich environment. However, Co may not be easily incorporated into SnS2. The doping with M at the Sn sites induces magnetic ground states in non‐magnetic SnS2. Additionally, a long‐range magnetic ordering is observed in SnS2 doped with V, Co, and Mo. In contrast, easy incorporation of O, Se, and Te at the S sites under the Sn‐rich environment has been observed while the semiconducting nature of SnS2 preserves with small band gaps.
Green to red and NIR tunable luminescence in heavily Er3+‐doped tellurite glasses via selective energy transfer mechanism
Authors: Wang Weirong , Yu Guanliang , Wang Ruibin , Jiang Chun 
Published: August 2019

AbstractHere, we select simple Er3+‐doped tellurite glass as model system to systematically explore the up‐conversion, down‐shifting mechanisms with different excitations (980 and 447 nm), respectively. We observe for the first time, to the best of our knowledge that tunable photo‐luminescence occurs from green to red and NIR region, rather than merely from the long‐accepted green to red region. Direct evidence of selective energy transfer mechanism is expounded in detail, and its potential applications are demonstrated. In addition, we provide evidence that the cross‐relaxation process between dopant ions can enhance photo‐luminescence in Er3+ doped tellurite glasses with high dopant concentrations, whereas the crucial reason for emission decrease is the energy loss long‐distance energy migration. These fundamental insights into the photophysical processes in heavily doped photonic glasses will broaden the applications of rare‐earth‐doped materials ranging from optical communications to medical imaging.
Long non‐coding RNA expressed in macrophage co‐varies with the inflammatory phenotype during macrophage development and polarization
Authors: Xie Yixin , Wang Min , Tian Jingjing , Li Xianping , Yang Min , Zhang Kan , Tan Shan , Luo Lingli , Luo Can , Peng Longkai , Tang Aiguo 
Published: August 2019

AbstractAdvances in microarray, RNA‐seq and omics techniques, thousands of long non‐coding RNAs (lncRNAs) with unknown functions have been discovered. LncRNAs have presented a diverse perspective on gene regulation in diverse biological processes, especially in human immune response. Macrophages participate in the whole phase of immune inflammatory response. They are able to shape their phenotype and arouse extensive functional activation after receiving physiological and pathological stimuli. Emerging studies indicated that lncRNAs participated in the gene regulatory network during complex biological processes of macrophage, including macrophage‐induced inflammatory responses. Here, we reviewed the existing knowledges of lncRNAs in the processes of macrophage development and polarization, and their roles in several different inflammatory diseases. Specifically, we focused on how lncRNAs function in macrophage, which might help to discover some potential therapeutic targets and diagnostic biomarkers.
Characterization of cowhage‐induced pruritus in inflamed and non‐inflamed skin
Authors: André F. , Fluhr J.W. , Hawro T. , Church M.K. , Maurer M. , Metz M. 
Published: August 2019

AbstractBackground and objectivePruritus is a major symptom of many inflammatory diseases and impacts greatly the quality of life in patients. We aimed to specify the characteristics of experimentally induced pruritus in normal skin and in experimentally induced inflammatory dermatitis in healthy volunteers.MethodsSkin inflammation was induced by the repeated application of sodium lauryl sulphate (SLS 2%) on the volar forearms of 30 healthy volunteers. Inflammatory dermatitis intensity was assessed using the eczema score adapted from Frosch and Kligman. Non‐histaminergic pruritus was induced by cowhage spicules rubbed on the volar forearms and recorded for 30 min on a 10‐cm visual analogue scale (VAS) in both non‐inflamed and inflamed skin.ResultsInduction of inflammatory dermatitis by SLS resulted in a mild inflammatory dermatitis with an inflammation score of 2.3 ± 0.1 within 7 days of treatment. Cowhage‐induced pruritus was of markedly higher intensity (P < 0.001), and all but two individuals had higher maximum pruritus intensity in inflamed skin as compared to non‐inflamed skin, whereas the kinetics of the pruritus response were similar. The quality of cowhage‐induced pruritus was significantly different with more ‘burning’ and ‘painful sensations’ in inflamed skin (P < 0.01). Maximum pruritus intensity in inflamed skin strongly correlated with maximum pruritus intensity in non‐inflamed skin (r = 0.51, P = 0.004). Skin hydration, skin barrier integrity and dermatitis severity did not correlate with pruritus intensity.ConclusionTaken together, pruritus in inflamed skin is perceived as more intense, painful and burning. This may explain, in part, why pruritus is a major driver of quality‐of‐life impairment in patients with chronic inflammatory skin conditions such as atopic dermatitis.
The epidemic of methylisothiazolinone contact allergy in Europe: follow‐up on changing exposures
Authors: Uter W. , Aalto‐Korte K. , Agner T. , Andersen K.E. , Bircher A.J. , Brans R. , Bruze M. , Diepgen T.L. , Foti C. , Giménez Arnau A. , Gonçalo M. , Goossens A. , McFadden J. , Paulsen E. , Svedman C. , Rustemeyer T. , White I.R. , Wilkinson M. , Johansen J.D. ,   on behalf of the European Environmental Contact Dermatitis Research Group
Published: August 2019

AbstractBackgroundMethylisothiazolinone (MI) has caused an unprecedented epidemic of contact allergy in Europe and elsewhere. Subsequently, regulatory action has been taken, at least in Europe, aiming at reducing risk of MI sensitization.ObjectiveTo follow‐up on the prevalence of contact allergy to MI in consecutively patch tested patients and assess the spectrum of products containing MI or methylchloroisothiazolinone (MCI)/MI in patients positive to MI which elicited current allergic contact dermatitis.MethodsA cross‐sectional survey was performed in 2016 and 2017, including all adult patients patch tested with the baseline series (including MI 0.2% aq.) between 1 May and 31 October at 14 centres in 11 European countries. Patients with positive reactions (+ to +++) to MI were further examined regarding history, clinical characteristics and eliciting products, which were categorized into 34 types and 4 classes (leave‐on, rinse‐off, household, occupational). The results were compared with the reference year 2015.ResultsA total of 317 patients, n = 202 of 4278 tested in 2016 (4.72%) and n = 115 of 3879 tested in 2017 (2.96%), had positive reactions to MI; the previous result from 2015 was 5.97% (P < 0.0001). The share of currently relevant contact allergy among all positive reactions declined significantly as well (P = 0.0032). Concerning product classes, a relative decline of leave‐on and a relative increase of rinse‐off and household products was noted.ConclusionThe prevalence of MI contact allergy decreased by 50% from 2015 to 2017. As a consequence of regulation, the share of cosmetics products (leave‐on in particular) eliciting allergic contact dermatitis is decreasing. The chosen method of analysing causative products in sensitized patients has proven useful to monitor effects of intervention.
Users of biologics in clinical practice: would they be eligible for phase III clinical studies? Cohort Study in the French Psoriasis Registry PSOBIOTEQ
Authors: Masson Regnault M. , Castañeda‐Sanabria J. , Diep Tran M.H.T. , Beylot‐Barry M. , Bachelez H. , Beneton N. , Chosidow O. , Dupuy A. , Joly P. , Jullien D. , Mahé E. , Richard M.‐A. , Viguier M. , Tubach F. , Sbidian E. , Paul C. ,   The PsoBioTeq Study Group
Published: August 2019

AbstractBackgroundNumerous inclusion and exclusion criteria are involved in phase III moderate to severe psoriasis trials investigating the safety and efficacy of biologics. This questions the generalization of results.MethodsIn this cohort study, we applied inclusion/exclusion criteria for phase III trials from original protocols (adalimumab – REVEAL, ustekinumab – PHOENIX, brodalumab – AMAGINE, secukinumab FIXTURE) to all patients enrolled in the PsoBioTeq prospective registry who received a biological agent for the first time between July 2012 and November 2017. We then compared the efficacy, drug survival and occurrence of adverse events between patients who satisfied/did not satisfy the eligibility criteria for these phase III trials.ResultsA total of 1267 patients were enrolled, of whom 993 (78.4%) were not eligible for at least one RCT (randomized controlled trial) and 251 (19.1%) did not meet the PASI/PGA severity requirements. Apart from disease severity, the most frequent criteria resulting in exclusion were as follows: non‐plaque psoriasis (12.6%), significant cardiac disease (8.4%), significant liver disease (7.3%), elevated liver enzymes (4.9–9.6%) and personal history of diabetes (9.2%). There was no difference in drug survival between the two groups. The incidence ratio of adverse events was significantly lower in eligible versus non‐eligible patients [0.78 (95% CI 0.62–0.97) (P = 0.03)].ConclusionThe majority of patients treated with biologics in the PsoBioTeq real‐life registry would not have been eligible for phase III moderate to severe psoriasis trials. Patients not eligible for psoriasis phase III clinical trials have a higher incidence of adverse events.
UAA and UAG may Encode Amino Acid in Cathepsin B Gene of Euplotes octocarinatus
Authors: Wang Ruanlin , Liu Jingni , Di Giuseppe Graziano , Liang Aihua 
Published: August 2019

AbstractThe ciliate Euplotes deviates from the universal genetic code by translating UGA as cysteine and using UAA and UAG as the termination codon. Here, we cloned and sequenced the Cathepsin B gene of Euplotes octocarinatus (Eo‐CTSB) which containing several in‐frame stop codons throughout the coding sequence. We provide evidences, based on 3′‐RACE method and Western blot, that the Eo‐CTSB gene is actively expressed. Comparison of the derived amino acid sequence with the homologs in other eukaryotes revealed that UAA and UAG may code for glutamine in Eo‐CTSB. These findings imply an evolutionary complexity of stop codon reassignment in eukaryotes.
Batch and continuous cultivation processes of Candida tropicalis TISTR 5306 for ethanol and pyruvate decarboxylase production in fresh longan juice with optimal carbon to nitrogen molar ratio
Authors: Nunta Rojarej , Techapun Charin , Jantanasakulwong Kittisak , Chaiyaso Thanongsak , Seesuriyachan Phisit , Khemacheewakul Julaluk , Mahakuntha Chatchadaporn , Porninta Kritsadaporn , Sommanee Sumeth , Trinh Ngoc T. , Leksawasdi Noppol 
Published: August 2019

AbstractThe carbon to nitrogen (C/N) molar ratio of 21.88 ± 0.20 in fresh juice from C‐grade longan (FLJ‐C) supplemented with ammonium sulfate (AMS) was optimal for cultivation of Candida tropicalis TISTR 5306 producing ethanol concentration of 24.0 ± 1.1 g/L and specific pyruvate decarboxylase (PDC) activity of 0.138 ± 0.001 U/mg protein. The highest ethanol concentration in a 10 L continuous process (34.3 ± 0.5 g/L, dilution rate [D] = 0.0492 hr−1) was significantly higher (p ≤ .05) than that in 100 L batch process (13.2 ± 0.2 g/L at 108 hr). The highest volumetric PDC activities of 0.081 ± 0.001 U/ml (D = 0.0070 hr−1) and 0.107 ± 0.001 U/ml (48 hr) were attained for continuous and batch processes, respectively. The affinity constants and growth‐related weighting factors on sucrose and monosaccharides (glucose and fructose with the same values) utilization were (123 ± 1 g/L, 0.14 ± 0.01) and (34.1 ± 1.5 g/L, 0.43 ± 0.01) with MS and R2 of 92.2 and .9552, respectively.Practical applicationsFLJ‐C is an example of agricultural produces with relatively high production quantity (50,000 t/year in Thailand) and high sugars content but low marketing demands due to the smallest size of pulp. The complex nitrogen source contains costly components (yeast extract—78.3 USD/kg, malt extract—148 USD/kg, and peptone—151 USD/kg) which can be replaced with an inexpensive AMS (1.05 USD/kg). Further consideration of C/N molar ratio in FLJ‐C can optimize growth, ethanol (alternative biofuel/industrial solvent) production, and specific PDC (biocatalyst for phenylacetylcarbinol—PAC, anti‐asthmatic and nasal decongestant precursors) activity of C. tropicalis TISTR 5306 whole cells which can be used as a case study for other related yeasts. Batch and continuous production at 100 L and 10 L also illustrate practical utilization of FLJ‐C with AMS supplement at larger scales for development of subsequent zero waste process.