bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Fungsional Terapi Tradisional dan Terapi Komplementer Alternatif Diera Jaminan Kesehatan Nasional (JKN)
Authors: Artana I Wayan 
Published: September 2019

Pelayanan dibidang kesehatan lebih baik dilakukan secara menyeluruh, karena manusia tidak dapat dipandang secara bagian perbagian. Kesepuluh sistem organ bekerjanya secara fungsional dalam mempertahankan tubuh agar tetap dalam keadaan seimbang. Penanganan penyakit secara menyeluruh/komprehensif meliputi penanganan secara konvensional dan non konvensional. Tulisan ini menggunakan metode analisis studi kepustakaan tentang peranan terapi non konvensional dalam penanganan penyakit.Penanganan konvensional meliputi semua penanganan yang telah terbukti secara ilmiah dan sudah dipergunakan oleh kalangan medis, sedangkan penanganan non konvensional belum seluruhnya terbukti secara ilmiah tetapi sudah ada digunakan oleh kalangan medis. Tujuan dari penulisan ini mengetahui peran yang bisa diambil oleh terapi non konvensional dalam penanganan penyakit diera JKN. Penanganan non konvensional terdiri dari terapi tradisional dan terapi komplementer alternative. Terapi ini ada beberapa yang sudah diperbolehkan digunakan sebagai terapi tambahan atau terapi pelengkap pada penanganan pasien, asalkan tidak bertentaangan dengaan terapi medis konvensional. Hal ini dibuktikan dengan telah diundangkannya peraturan peraturan mengenai terapi tradisional dan komplementer alternative. Hasil tulisan ini dapat dipergunakan oleh kalangan medis untuk penanganan penyakit yang menyeluruh sehingga pasien menjadi lebih puas. Begitu juga dapat memberikan hasil yang baik kepada kendali mutu dan kendali biaya pada program Badan Penyelenggara Jaminan Sosial Kesehatan (BPJS Kesehatan). Perlu dilakukan penelitian dan pengembangan obat obatan tradisional dan obat komplementer alternatif oleh institusi pendidikan STIKES Bina Usada dan institusi kesehatan lain. Memasukkan terapi tradisional dan komplementer alternatif kedalam materi pengajaran kepada anak didik sehingga mereka lebih mengenal manfaat dan keuntungan penanganan pasien secara komprehensif.
Pengaruh Masase Perineum pada Derajat Laserasi Perineum Terhadap Primigravida di Puskesmas II Denpasar Barat
Authors: Putri Yustika Rani Anak Agung , Prihandhani IGAA Sherlyna 
Published: September 2019

Laserasi perineum adalah robekan yang terjadi pada perineum sewaktu persalinan. Kerusakan tersebut biasanya lebih nyata pada primigravida dibandingkan multigravida. Salah satu pencegahan yang dapat dilakukan untuk mengurangi laserasi perineum yaitu masase perineum. Masase perineum merupakan teknik memijat pada daerah perineum pada masa kehamilan atau beberapa minggu menjelang persalinan guna meningkatkan perubahan hormonal yang melembutkan jaringan ikat, sehingga jaringan perineum lebih elastis dan lebih mudah meregang. Tujuan dari penelitian ini untuk mengetahui pengaruh masase perineum terhadap derajat laserasi perineum pada primigravida di Puskesmas II Denpasar Barat. Penelitian ini merupakan penelitian true eksperiment, dengan rancangan pasca-test dengan pemilihan, dimana kelompok eksperimen diberi perlakuan sedangkan kelompok kontrol tidak. Pada kedua kelompok tidak diawali dengan pra-tes. Pengukuran hanya dilakukan setelah pemberian perlakuan selesai. Data di analisis dengan uji statistik menggunakan uji Mannn-Withney U Test nilai U statistik adalah 20,0 dan nilai U tabel (n1 = 10, n2 = 10 dengan a = 0,05) adalah 23 Nilai U statistik = 20 < 23 = nilai U tabel, maka Ho ditolak dan H1 diterima. Berarti terdapat perbedaan antara derajat laserasi yang diberikan masase dengan yang tidak diberikan masase.
Studi Fenomenologi Pengalaman Orang Dengan HIV/AIDS Dalam Mencegah Penularan HIV
Authors: Suprayitna Marthilda , Setiawan Agus , Azzam Rohman 
Published: September 2019

Angka kejadian HIV di Kota Mataram meningkat dalam 5 tahum terakhir. Upaya yang telah dilakukan oleh Pemerintah setempat terkait penanggulangan HIV/AIDS yang sudah dilaksanakan selama ini seperti melakukan pencegahan – pencegahan pada lingkungan agar tidak terkena penularan virus HIV/AIDS melalui kampanye dan penyuluhan tentang penggunaan kondom dan melakukan pengobatan untuk mereka yang sudah positif HIV/AIDS. Tujuan penelitian ini untuk mengeksplorasi pengalaman orang dengan HIV/AIDS dalam mencegah penularan HIV. Metodologi yang digunakan adalah fenomenologi dengan jumlah partisipan sebanyak 6 orang, data dikumpulkan melalui wawancara mendalam. Wawancara direkam dan kemudian dibuat dalam bentuk verbatim. Hasil penelitian mengungkapkan variasi berbagai pengalaman orang dengan HIV/AIDS dalam mencegah penularan. Lima tema didapatkan dalam penelitian ini meliputi partisipan terdiagnosis HIV/AIDS, upaya partisipan dalam pencegahan penularan, hambatan partisipan serta motivasi partisipan dalam pencegahan penularan HIV/AIDS, dan dukungan yang diterima partisipan dalam upaya pencegahan penularan HIV. Berdasarkan temuan hasil tema tersebut disarankan agar perawat membantu upaya promosi kesehatan, partisipan mendapatkan dukungan dan motivasi untuk meningkatkan perilaku pencegahan penularan HIV/AIDS
ANALISIS MOMEN POROS DAN GAYA SAMPING HORN RUDDER BIDANG KENDALI PESAWAT N-XXX MENGGUNAKAN COMPUTATIONAL FLUID DYNAMIC
Authors: Muchammad Muchammad 
Published: September 2019

Pesawat merupakan sarana transportasi yang memiliki arti penting bagi pembangunan ekonomi dan pertahanan, mengingat bahwa Indonesia adalah sebuah Negara kepulauan dengan kondisi geografis yang sulit untuk diakses tanpa sarana transportasi yang memadai. Penelitian ini bertujuan agar mendapatkan koefisiean hinge moment dan side force bidang kendali ekor pesawat N-XXX pada bagian rudder horn dengan variasi defleksi dengan derajat tertentu. Metode yang digunakan untuk analisis aerodinamika ada beberapa macam, yakni metode analisis Computational Fluid Dynamic (CFD) dan eksperimen yang biasa dilakukan dengan uji terowongan angin yang menawarkan tingkat keakuratan hasil lebih nyata namun dengan biaya yang lebih besar. Metode yang digunakan pada penelitian ini adalah analisis dengan metode Computational Fluid Dynamic (CFD). Penelitian dilakukan dengan variasi defleksi pada horn rudder sebesar 0°,10°,20° untuk mengetahui nilai hinge moment dan side force dengan langkah mengidealisasi geometri, meshing dan diselesaikan dengan CFD untuk perhitungannya guna mendapatkan nilai hinge moment dan side force. Pada defleksi 0° mempunyai nilai hinge moment -0.588, defleksi 10° mempunyai nilai hinge moment 0.653 dan defleksi 20° mempunyai nilai hinge moment -3.836 sedangkan untuk nilai side force pada defleksi 0° mempunyai nilai side force -0.999, defleksi pada 10° mempunyai nilai side force 70.908, defleksi 20° mempunyai nilai side force 106.773.Kata kunci: ekor pesawat, defleksi, hinge moment, rudder horn, side force.
Comparison of the Toric Implantable Collamer Lens and Custom Ablation LASIK for Myopic Astigmatism
Authors: Sanders Donald R. , Sanders Monica L. 
Published: September 2019

Purpose
To compare the results of wavefront-guided custom LASIK and the Toric Implantable Collamer Lens (TICL) in the correction of myopic astigmatism.

Methods
This observational, non-randomized study compared clinical efficacy results from the TICL's US Food and Drug Administration Clinical Trial and published Summaries of Safety and Effectiveness of two wavefront-guided lasers: STAR S4 CustomVue excimer laser system (VISX Inc) and LADARVision4000 Custom-Cornea excimer laser system (Alcon Laboratories Inc). Preoperative myopic refractive error was divided into two groups: −3.00 to −7.00 diopters (D) and −7.00 to −11.00 D.

Results

The percentage of eyes with uncorrected visual acuity (UCVA) of 20/20 and 20/40 and predictability of manifest refraction spherical equivalent within ±0.50 and ±1.00 D in the three groups was similar with only one statistically significant difference (TICL versus Alcon within ±1.00 D: 97% versus 82%;
P
=.008). The TICL had significantly better postoperative best spectacle-corrected visual acuity (BSCVA) compared to preoperative BSCVA than both the VISX CustomVue and Alcon CustomCornea (
P
<.001). The TICL postoperative UCVA outcomes compared to preoperative BSCVA were significantly better than Alcon CustomCornea outcomes (
P
<.001). Additionally, almost half (48%) of the TICL cases had improvement in postoperative UCVA compared to preoperative BSCVA, whereas only 23% of the Alcon CustomCornea eyes showed improvement.

Conclusions

Although comparable in clinical efficacy outcomes, the TICL had a significantly better postoperative improvement in BSCVA and significantly better postoperative UCVA than preoperative BSCVA. The TICL can be considered as an alternative to LASIK through the full range of use. [
J Refract Surg.
2008;24:773–778.]
Comparison of Higher Order Aberrations Measured by NIDEK OPD-Scan Dynamic Skiascopy and Zeiss WASCA Hartmann-Shack Aberrometers
Authors: Cerviño Alejandro , Hosking Sarah L. , Montés-Micó Robert 
Published: September 2019

Purpose
To compare the measurement of wavefront aberrations in non-cyclopleged human eyes with Hartmann-Shack and dynamic skiascopy wavefront analyzers.

Methods

Eighty eyes of 40 healthy young adults (19 men, 21 women; mean age 20.8±2.5 years) with refractive errors ranging from +1.50 to −9.75 diopters (D) sphere and up to 1.75 D cylinder (mean spherical equivalent refraction −2.12±2.69 D) were examined with the Zeiss/Meditec WASCA and NIDEK OPD-Scan wavefront analyzers and with the Nippon SRW5000 binocular, open-field autorefractor without the instillation of antimuscarinic agents. Three measurements were taken with each system, in randomized sequence. To avoid differences due to instrument myopia, eyes were excluded if mean spherical equivalent refraction with any of the analyzers exceeded those obtained with the SRW5000 by more than 1.00 D; 13 eyes were excluded. Coefficient of repeatability was determined for the WASCA as the confidence interval (CI) for the differences between the repeated measures. Paired
t
tests with Bonferroni adjustment for multiple comparisons, correlation analysis, and Bland-Altman plots of difference versus mean were performed.

Results

The coefficient of repeatability for the WASCA ranged from 0.008 to 0.022 µm. Data distribution was normal for all Zernike coefficients measured with WASCA, but only for

Z

3

-
1

,

Z

3
1

, and

Z

4
0

measured with the OPD-Scan. Mean differences between instruments in coefficients

Z

3

-
3

,

Z

3
1

,

Z

3
3

,

Z

4
0

, and

Z

4
2

and higher order root-meansquare (RMS) reached statistical significance (mean difference±CI: −0.054±0.021, −0.056±0.022, and 0.030±0.016 µm, respectively,
P
<.05 in all cases). Correlation coefficients were significant only for higher order RMS (Spearman's rho=0.777;
P
>.001).

Conclusions

Although agreement is shown for higher order RMS, aberration values obtained with dynamic skiascopy and Hartmann-Shack systems on non-cyclopleged human eyes are not well correlated with each other, and are therefore not interchangeable. [
J Refract Surg
. 2008;24:790–796.]
Subconjunctival Gas Bubble Formation During LASIK Flap Creation Using Femtosecond Laser
Authors: Ide Takeshi , Kymionis George D. , Goldman David A. , Yoo Sonia H. , O'Brien Terrence P. 
Published: September 2019

Purpose
To report a patient who developed subconjunctival gas bubble formation during creation of a LASIK corneal flap with the IntraLase femtosecond laser.

Methods
Case report of a 19-year-old-man with compound myopic astigmatism and a normal preoperative evaluation who underwent bilateral simultaneous LASIK.

Results
The IntraLase FS15 was used to create an 8.8-mm diameter superior flap. Laser settings were 110-µm depth, 1.70-mJ bed and side-cut energy, 12-µm spot separation, 10-µm line separation, 70° side-cut angle, 240-µm pocket start width, and 200-µm pocket start depth. The procedure was uneventful in the right eye whereas subconjunctival air bubbles were observed along the corneal limbus in the left eye (no bubbles were seen in the peripheral cornea). The patient was examined 30 minutes later, and the subconjunctival bubbles could still be observed. By the next day, the bubbles had disappeared completely. Postoperative uncorrected visual acuity was 20/20 in both eyes.

Conclusions

Subconjuctival bubbles can be found after LASIK flap creation with a femtosecond laser. [
J Refract Surg
. 2008;24:850–851.]
Assessment of Keratocyte Activation Following LASIK With Flap Creation Using the IntraLase FS60 Laser
Authors: Petroll W. Matthew , Bowman R. Wayne , Cavanagh H. Dwight , Verity Steven M. , Mootha V. Vinod , McCulley James P. 
Published: September 2019

Purpose
To assess the response of corneal keratocytes to the IntraLase FS60 femtosecond laser using attenuated steroids.

Methods
Thirty patients (30 eyes) who underwent LASIK with the IntraLase FS60 were assessed by clinical examination and confocal microscopy 3 months postoperatively. Postoperative steroid regimen was Econopred Plus (Alcon Laboratories Inc) every hour for 1 day and four times daily for 7 days.

Results

No cornea had clinically significant flap interface haze. Two corneas had trace haze at the interface detected by slit-lamp examination; both showed significant keratocyte activation by confocal microscopy. Overall, some degree of keratocyte activation was detected at the flap interface in 10 of 30 eyes. The measured interface reflectivity was 328.8±85.0 confocal backscatter units (CBU) in eyes with activated keratocytes and 88.9±74.5 CBU for the remaining 19 eyes (
P
<.001).

Conclusions

With attenuated steroids, keratocyte activation was found in a significant number of eyes, although interface haze was subclinical. A higher steroid dosage might therefore be indicated. [
J Refract Surg
. 2008;24:847–849.]
The first five years' clinical experience of the Australian National Liver Transplantation Unit
Authors: Sheil A G Ross , McCaughan Geoffrey W , Thompson John F , Stephen Michael S , Bookallil Michael J , Dorney Stuart F A 
Published: September 2019

ObjectiveTo report the first five years' clinical experience of the Australian National Liver Transplant Unit.PatientsThree hundred and seventy patients were referred — 292 adults (79%) and 78 children (21%). The major causes of liver failure in the adults were chronic active hepatitis (25%), primary biliary cirrhosis (12%), primary sclerosing cholangitis (12%), alcoholic cirrhosis (9%) and malignancy (9%). Ten per cent of patients were referred in fulminant hepatic failure. In children, the major causes were biliary atresia (40%) and inborn errors in metabolism (27%).ResultsTwo hundred and sixty‐three patients (71%) were accepted for transplantation. Of 158 (43%) accepted for early transplantation, 22 (14%) died before a donor became available. Four hundred and forty‐ three suitable organ donors were referred. One hundred and twenty‐six patients, including 32 children (25%), received 137 grafts. Three patients with renal failure due to hyperoxaluria type 1 received concurrent renal grafts. Ninety‐two patients survived (73%). For all recipients, one‐year survival was 75%. Two, three and four‐year survivals were 69%. One to four‐year survivals for adults with benign conditions were 77%, contrasting with results for those with hepatic malignancy (40% one‐year survival). Children weighing more than 8 kg had good outcomes whether they received whole grafts or reduced‐size grafts (83% one to five‐year survival in both cases). Infants weighing less than 8 kg who received reduced adult grafts did significantly worse (37% one to‐five year survival, P<0.05). Thirteen (87%) of 15 patients with fulminant hepatic failure who received grafts survived. Five of these patients were given ABO‐incompatible grafts and two subsequently required retransplantation. All three patients with concurrent renal and hepatic grafts survived. Rehabilitation of survivors was excellent with 95% of adults and 100% of children pursuing normal activities. Only three grafts (2%) failed with primary non‐function, all in infants because of graft infarction. Graft survival was significantly worse (P<0.01) in patients with a positive result to a direct cross match test against the donor.ConclusionsThe need for liver transplantation in Australia is approximately eight per million of population per year. More donor offers are required to prevent deaths of patients on the waiting list. Reduced‐size livers are successful for children and have alleviated considerably the critical shortage of paediatric donor livers. Successful treatment by liver transplantation can now be achieved in more than 80% of patients With non‐malignant liver disorders including those with fulminant hepatic failure not responding to conservative therapy.
Brodifacoum does not modulate human cannabinoid receptor-mediated hyperpolarization of AtT20 cells or inhibition of adenylyl cyclase in HEK 293 cells
Authors: Sachdev Shivani , Boyd Rochelle , Grimsey Natasha L. , Santiago Marina , Connor Mark 
Published: September 2019

BackgroundSynthetic cannabinoids are a commonly used class of recreational drugs that can have significant adverse effects. There have been sporadic reports of co-consumption of illicit drugs with rodenticides such as warfarin and brodifacoum (BFC) over the past 20 years but recently, hundreds of people have been reported to have been poisoned with a mixture of synthetic cannabinoids and BFC. We have sought to establish whether BFC directly affects cannabinoid receptors, or their activation by the synthetic cannabinoid CP55940 or the phytocannabinoid Δ9-tetrahydrocannabinol (Δ9-THC).MethodsThe effects of BFC on the hyperpolarization of wild type AtT20 cells, or AtT20 cells stably expressing human CB1- or CB2- receptors, were studied using a fluorescent assay of membrane potential. The effect of BFC on CB1- and CB2-mediated inhibition of forskolin-stimulated adenylyl cyclase (AC) activation was measured using a BRET assay of cAMP levels in HEK 293 cells stably expressing human CB1or CB2.ResultsBFC did not activate CB1or CB2receptors, or affect the hyperpolarization of wild type AtT20 cells produced by somatostatin. BFC (1 µM) did not affect the hyperpolarization of AtT20-CB1or AtT20-CB2cells produced by CP55940 or Δ9-THC. BFC (1 µM) did not affect the inhibition of forskolin-stimulated AC activity by CP55940 in HEK 293 cells expressing CB1or CB2. BFC (1 µM) also failed to affect the desensitization of CB1and CB2signaling produced by prolonged (30 min) application of CP55940 or Δ9-THC to AtT20 cells.DiscussionBFC is not a cannabinoid receptor agonist, and appeared not to affect cannabinoid receptor activation. Our data suggests there is no pharmacodynamic rationale for mixing BFC with synthetic cannabinoids; however, it does not speak to whether BFC may affect synthetic cannabinoid metabolism or biodistribution. The reasons underlying the mixing of BFC with synthetic cannabinoids are unknown, and it remains to be established whether the “contamination” was deliberate or accidental. However, the consequences for people who ingested the mixture were often serious, and sometimes fatal, but this seems unlikely to be due to BFC action at cannabinoid receptors.
Acceptance and verification of the Halcyon‐Eclipse linear accelerator‐treatment planning system without 3D water scanning system
Authors: Gao Song , Netherton Tucker , Chetvertkov Mikhail A. , Li Yuting , Court Laurence E. , Simon William E. , Shi Jie , Balter Peter A. 
Published: September 2019

AbstractWe tested whether an ionization chamber array (ICA) and a one‐dimensional water scanner (1DS) could be used instead of a three‐dimensional water scanning system (3DWS) for acceptance testing and commissioning verification of the Varian Halcyon–Eclipse Treatment Planning System (TPS). The Halcyon linear accelerator has a single 6‐MV flattening‐filter‐free beam and a nonadjustable beam model for the TPS. Beam data were measured with a 1DS, ICA, ionization chambers, and electrometer. Acceptance testing and commissioning were done simultaneously by comparing the measured data with TPS‐calculated percent‐depth‐dose (PDD) and profiles. The ICA was used to measure profiles of various field sizes (10‐, 20‐, and 28 cm2) at depths of dmax (1.3 cm), 5‐, 10‐, and 20 cm. The 1DS was used for output factors (OFs) and PDDs. OFs were measured with 1DS for various fields (2–28 cm2) at a source‐to‐surface distance of 90 cm. All measured data were compared with TPS‐calculations. Profiles, off‐axis ratios (OAR), PDDs and OFs were also measured with a 3DWS as a secondary check. Profiles between the ICA and TPS (ICA and 3DWS) at various depths across the fields indicated that the maximum discrepancies in high‐dose and low‐dose tail were within 2% and 3%, respectively, and the maximum distance‐to‐agreement in the penumbra region was <3 mm. The largest OAR differences between ICA and TPS (ICA and 3DWS) values were 0.23% (−0.25%) for a 28 × 28 cm2 field, and the largest point‐by‐point PDD differences between 1DS and TPS (1DS and 3DWS) were −0.41% ± 0.12% (−0.32% ± 0.17%) across the fields. Both OAR and PDD showed the beam energy is well matched to the TPS model. The average ratios of 1DS‐measured OFs to the TPS (1DS to 3DWS) values were 1.000 ± 0.002 (0.999 ± 0.003). The Halcyon–Eclipse system can be accepted and commissioned without the need for a 3DWS.
Dielectrics for Terahertz Metasurfaces: Material Selection and Fabrication Techniques
Authors: Ako Rajour Tanyi , Upadhyay Aditi , Withayachumnankul Withawat , Bhaskaran Madhu , Sriram Sharath 
Published: September 2019

AbstractManipulation of terahertz radiation opens new opportunities that underpin application areas in communication, security, material sensing, and characterization. Metasurfaces employed for terahertz manipulation of phase, amplitude, or polarization of terahertz waves have limitations in radiation efficiency which is attributed to losses in the materials constituting the devices. Metallic resonators‐based terahertz devices suffer from high ohmic losses, while dielectric substrates and spacers with high relative permittivity and loss tangent also reduce bandwidth and efficiency. To overcome these issues, a proper choice of low loss and low relative permittivity dielectric layers and substrates can improve field confinement and reduce dissipation. Alternatively, replacing metallic resonators with a moderate relative permittivity dielectric material that supports cavity mode resonances also reduces dissipation due to the absence of conduction current. Herein, an overview of dielectric materials employed as spacers and dielectric resonators is provided, and the fabrication methods employed to realize these devices at the terahertz frequency range are also presented. Material selection guidelines, material‐specific and application‐specific fabrication quality metrics are outlined, and new techniques are proposed.
An Electrophilic Ruthenium Complex that Enables the Cycloisomerization of 1,6‐Enynes to Access Azabicyclo[4.1.0]heptenes
Authors: Liu Rui , Yang Dongfeng , Chang Fengwei , Giordano Laurent , Liu Guohua , Tenaglia Alphonse 
Published: September 2019

AbstractCycloisomerization of 1,6‐enynes to access azabicyclo[4.1.0]heptenes was achieved in the presence of commercially available [RuCl2(CO)3]2 after a comprehensive study on the electronic properties of ruthenium complexes. A series of 1,6‐enynes bearing an internal/terminal alkyne motif proved to be good candidates for substrates, giving their corresponding bicyclo[4.1.0]heptenes in good to excellent yields. Substitution patterns on either alkyne or alkene have no significant influence on the yields of bicyclic adducts.