bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physical activity and impaired left ventricular relaxation in middle aged adults
Authors: Ryu Seungho , Chang Yoosoo , Kang Jeonggyu , Yun Kyung Eun , Jung Hyun-Suk , Kim Chan-Won , Cho Juhee , Lima Joao A , Sung Ki-Chul , Shin Hocheol , Guallar Eliseo 
Published: August 2018

AbstractThe aim of this study was to examine the relationship between physical activity level and impaired left ventricular (LV) relaxation in a large sample of apparently healthy men and women. We conducted a cross-sectional study in 57,449 adults who underwent echocardiography as part of a comprehensive health examination between March 2011 and December 2014. Physical activity level was assessed using the Korean version of the International Physical Activity Questionnaire Short Form. The presence of impaired LV relaxation was determined based on echocardiographic findings. Physical activity levels were inversely associated with the prevalence of impaired LV relaxation. The multivariable-adjusted odds ratios (95% confidence interval) for impaired LV relaxation comparing minimally active and health-enhancing physically active groups to the inactive group were 0.84 (0.77–0.91) and 0.64 (0.58–0.72), respectively (P for trend < 0.001). These associations were modified by sex (p for interaction <0.001), with the inverse association observed in men, but not in women. This study demonstrated an inverse linear association between physical activity level and impaired LV relaxation in a large sample of middle-aged Koreans independent of potential confounders. Our findings suggest that increasing physical activity may be independently important in reducing the risk of impaired LV relaxation.
One millennium of historical freshwater fish occurrence data for Portuguese rivers and streams
Authors: Duarte Gonçalo , Moreira Miguel , Branco Paulo , da Costa Luís , Ferreira Maria Teresa , Segurado Pedro 
Published: August 2018

AbstractThe insights that historical evidence of human presence and man-made documents provide are unique. For example, using historical data may be critical to adequately understand the ecological requirements of species. However, historical information about freshwater species distribution remains largely a knowledge gap. In this Data Descriptor, we present the Portuguese Historical Fish Database (PHish–DB), a compilation of 2214 records (557 at the basin scale, 184 at the sub-basin scale and 1473 at the segment scale) resulting from a survey of 194 historical documents. The database was developed using a three-scale approach that maximises the inclusion of information by allowing different degrees of spatial acuity. PHish database contains records of 25 taxonomical groups and covers a time span of one millennium, from the 11th until the 20th century. This database has already proven useful for two scientific studies, and PHish further use will contribute to correctly assess the full range of conditions tolerated by species, by establishing adequate benchmark conditions, and/or to improve existing knowledge of the species distribution limits.
A Case Study Using a Multimodal Approach to Melodic Intonation Therapy
Authors: Slavin Dianne , Fabus Renee 
Published: August 2018

Purpose
The purpose of this study was to assess the efficacy. of increasing spontaneous expressive language using a modified melodic intonation therapy (MIT) approach with a male participant diagnosed with acquired aphasia and apraxia who was 10 years post onset.

Method
A therapeutic protocol consisting of vocal and linguistic tasks was administered. The participant attended two 50-min individual sessions and a 4-hr/week socialization program for three 12-week semesters. Measures of speech and language were administered before intervention and at the completion of each of the 3 semesters.

Results
At the completion of the study, the participant demonstrated reduced apraxia of speech as measured by The Apraxia Battery for Adults, Second Edition (Dabul, 2000). He also showed improvements in auditory comprehension skills as measured on the Boston Diagnostic Aphasia Evaluation (Goodglass, Kaplan, & Barresi, 2000). His spontaneous utterances were characterized by an increased number of complete sentences and questions. Several language parameters including mean length of utterance, total number of spontaneous (untrained) utterances, and number of different words spoken were also improved as revealed through language analysis.

Conclusions
Integration of melodic intonation therapy through the addition of musical elements may result in improved speech and expressive language skills when administered over a 9-month period in conjunction with a group socialization program.
Individual and Developmental Differences in Distributional Learning
Authors: Hall Jessica , Owen Van Horne Amanda J. , McGregor Karla K. , Farmer Thomas A. 
Published: August 2018

Purpose
This study examined whether children and adults with developmental language disorder (DLD) could use distributional information in an artificial language to learn about grammatical category membership similarly to their typically developing (TD) peers and whether developmental differences existed within and between DLD and TD groups.

Method
Sixteen children ages 7–9 with DLD, 26 age-matched TD children, 17 college students with DLD, and 17 TD college students participated in this task. We used an artificial grammar learning paradigm in which participants had to use knowledge of category membership to determine the acceptability of test items that they had not heard during a training phase.

Results
Individuals with DLD performed similarly to TD peers in distinguishing grammatical from ungrammatical combinations, with no differences between age groups. The order in which items were heard at test differentially affected child versus adult participants and showed a relation with attention and phonological working memory as well.

Conclusion
Differences in ratings between grammatical and ungrammatical items in this task suggest that individuals with DLD can form grammatical categories from novel input and more broadly use distributional information. Differences in order effects suggest a developmental timeline for sensitivity to updating distributional information.
The Role of Statistical Learning in Understanding and Treating Spoken Language Outcomes in Deaf Children With Cochlear Implants
Authors: Deocampo Joanne A. , Smith Gretchen N. L. , Kronenberger William G. , Pisoni David B. , Conway Christopher M. 
Published: August 2018

Purpose
Statistical learning—the ability to learn patterns in environmental input—is increasingly recognized as a foundational mechanism necessary for the successful acquisition of spoken language. Spoken language is a complex, serially presented signal that contains embedded statistical relations among linguistic units, such as phonemes, morphemes, and words, which represent the phonotactic and syntactic rules of language. In this review article, we first review recent work that demonstrates that, in typical language development, individuals who display better nonlinguistic statistical learning abilities also show better performance on different measures of language. We next review research findings that suggest that children who are deaf and use cochlear implants may have difficulties learning sequential input patterns, possibly due to auditory and/or linguistic deprivation early in development, and that the children who show better sequence learning abilities also display improved spoken language outcomes. Finally, we present recent findings suggesting that it may be possible to improve core statistical learning abilities with specialized training and interventions and that such improvements can potentially impact and facilitate the acquisition and processing of spoken language.

Method
We conducted a literature search through various online databases including PsychINFO and PubMed, as well as including relevant review articles gleaned from the reference sections of other review articles used in this review. Search terms included various combinations of the following: sequential learning, sequence learning, statistical learning, sequence processing, procedural learning, procedural memory, implicit learning, language, computerized training, working memory training, statistical learning training, deaf, deafness, hearing impairment, hearing impaired, DHH, hard of hearing, cochlear implant(s), hearing aid(s), and auditory deprivation. To keep this review concise and clear, we limited inclusion to the foundational and most recent (2005–2018) relevant studies that explicitly included research or theoretical perspectives on statistical or sequential learning. We here summarize and synthesize the most recent and relevant literature to understanding and treating language delays in children using cochlear implants through the lens of statistical learning.

Conclusions
We suggest that understanding how statistical learning contributes to spoken language development is important for understanding some of the difficulties that children who are deaf and use cochlear implants might face and argue that it may be beneficial to develop novel language interventions that focus specifically on improving core foundational statistical learning skills.
Statistical Learning and Bilingualism
Authors: Bulgarelli Federica , Lebkuecher Amy L. , Weiss Daniel J. 
Published: August 2018

Purpose
Over the last 2 decades, research on statistical learning has demonstrated its importance in supporting language development. Notably, most of the research to date has focused on monolingual populations (or has not reported the language background of participants). Several recent studies, however, have begun to focus on the impact of bilingualism on statistical learning. To date, the results have been quite mixed, with a handful of studies finding differences between monolinguals and bilinguals and several other studies reporting no differences. Thus, the purpose of this manuscript is to review the literature to date on how bilingualism impacts statistical learning abilities.

Method
We review the contemporary literature, organized by the age of participants and by task when relevant.

Conclusions
We note that there are many discrepant	findings within this nascent field, although some trends have emerged. For instance, differences in performance may be attributed to factors such as age of acquisition. However, we note that the state of the field does not yet permit firm clinical recommendations.
Statistical Learning: How it Relates to Speech-Language Pathology
Authors: Alt Mary 
Published: August 2018

Purpose
The purpose of this special issue is to introduce speech-language pathologists to the topic of statistical learning and how this is relevant to their practice. In the following articles, the concept of statistical learning will be explained, and readers will find (a) research studies showing how children with special needs can use statistical learning to learn language; (b) tutorials that show why statistical learning is meaningful for special populations; and (c) tutorials that show how statistical learning is involved in language, reading, and spelling.
340 GHz lens‐coupled 4 × 4 GaAs detector array for terahertz imaging applications
Authors: Li Mingxun , Lv Xin , Mou Jinchao , Guo Dalu , Qiao Haidong , Ma Zhaohui , Hao Haidong 
Published: August 2018

A 340 GHz 4 × 4 detector array based on 0.18 µm gallium arsenide technology is presented. Each pixel is composed of a planar log‐periodic antenna, a Schottky barrier diode, and a pair of bonding pads. The detector array is mounted on a silicon lens and assembled onto a PCB using the authors’ novel flip‐chip structure. Off‐axis performances of the lens‐coupled detector array are demonstrated experimentally, which agree well with the simulated ones. The detector array shows a peak voltage responsivity of 1347 V/W and a noise equivalent power of 2.1 pW/Hz1/2 at 340 GHz, exhibiting much better performance than the CMOS counterpart.
Effect of ZnO nanosizing on its solubility in aqueous media
Authors: Leitner Jindřich , Sedmidubský David , Jankovský Ondřej 
Published: August 2018

Zinc pollution represents a great environmental risk, particularly with regards to the aquatic environment. In this theoretical contribution, the enhanced solubility of ZnO nanoparticles in pure water is predicted based on a simple thermodynamic model. The study used Zn2+, Zn(OH)+, Zn(OH)2, Zn(OH)3 − and Zn(OH)4 2− as dominant species in aqueous solution and a Gibbs energy minimisation method to calculate equilibrium Zn content in this solution. ZnO was investigated in the form of nanoparticles of various shapes, whose very high surface‐to‐volume ratio implicates their lower thermodynamic stability compared with bulk material. The interfacial energy of the solid ZnO – dilute aqueous solution interface was assessed by applying the average ZnO surface energy and contact angle of a sessile drop of water on ZnO()‐O surface. At 298 K, the ratio of 2 nm spherical ZnO particles to the bulk material solubility was about 23.7. The calculated results were compared with experimental data and yielded a good agreement. These results are not only of great importance for nanomaterials research but they also have implications for environmental protection.
Aufgaben beruflich Pflegender in der palliativen Schmerzversorgung von Tumorpatienten
Authors: Nestler Nadja , Krutter Simon , Wittling Thomas , Osterbrink Jürgen 
Published: August 2018

ZusammenfassungZiele einer palliativen Versorgung sind die Sicherung der Autonomie und Lebensqualität der Patienten sowie die Kontrolle ihrer Symptome, die insbesondere durch
die Stabilisierung der Schmerzsituation erreicht werden. Für die professionelle Versorgung von Patienten mit Tumorschmerzen ist die Berücksichtigung des
subjektiven Schmerzerlebens von besonderer Bedeutung. Damit verbunden ist die Notwendigkeit, im interprofessionellen Schmerzmanagement nach individuellen
Lösungen zu suchen. Die Aufgaben Pflegender im Schmerzmanagement können dabei in 3 Felder zusammengefasst werden: erstens klinische, edukative und
administrative Aufgaben, zweitens die interdisziplinäre Kooperation und Kommunikation sowie drittens die Mitwirkung bei schmerztherapeutischen Maßnahmen. Zur
Anwendung des Konzeptes der stabilen Schmerzsituation benötigen Pflegende Kompetenzen, um ein systematisches pflegerisches Schmerzmanagement unter Einbeziehung
von Pflegeexperten Schmerz und in Abstimmung mit dem interprofessionellen Team umsetzen zu können.
Acute Administration of Tibolone Prevents Oxidative Stress in Ovariectomized Rats Fed High-Fat-and-Fructose Diet
Authors: Estrada Cruz Norma Angélica , Almanza Pérez Julio César , Fortis Barrera Ángeles , Gallardo Juan Manuel , Manuel Apolinar Leticia , Segura Uribe Julia Jeanett , Orozco Suárez Sandra , Coyoy Salgado Angélica , Guerra Araiza Christian 
Published: August 2018

AbstractIn addition to oxidative stress due to the increase of free radicals, estrogen deficiency is associated with changes in enzymatic activity, glutathione redox ratio (GSH/GSSG), and the content of oxidative markers such as malondialdehyde. Tibolone, a synthetic steroid, has been used as an elective treatment for the relief of menopausal symptoms. However, the acute effects of hormonal therapy with tibolone on metabolic parameters and oxidative stress markers associated with the first stages of estrogen deficiency are still unknown. The study aimed to evaluate if the acute administration of tibolone reduces oxidative stress in ovariectomized rats fed high-fat-and-fructose diet. Rats were fed a standard diet or a diet consisting of 10% lard-supplemented chow and 20% high-fructose syrup in the drinking water plus tibolone or vehicle for seven days. Weight, cholesterol, triglycerides, and glucose levels, as well as antioxidant enzymes and oxidative stress markers were quantified in the serum of each experimental group. It was observed that seven days of diet and tibolone treatment in the ovariectomized group reduced weight, triglycerides, cholesterol, glucose levels and advanced glycation end products but did not change GSH/GSSG ratio nor the enzymatic activity of superoxide dismutase. Also, both glutathione peroxidase and glutathione reductase activity decreased, as well as malondialdehyde levels. These results suggest that the acute treatment with tibolone prevented the changes in the metabolic parameters analyzed as well as the increase in the levels of malondialdehyde and AGEs induced by ovariectomy and high-fat diet.
Österreichisches Benchmarking ERCP: 10-Jahresbericht
Authors: Kienbauer Melanie , Duller Christine , Gschwantler Michael , Püspök Andreas , Schöfl Rainer , Kapral Christine 
Published: August 2018

ZusammenfassungSeit 10 Jahren überblickt das Qualitätssicherungsprogramm „Benchmarking ERCP“ unter der Patronanz der Österreichischen Gesellschaft für Gastroenterologie und Hepatologie (ÖGGH) mit einjähriger Unterbrechung (2008) in Zusammenarbeit mit dem Institut für Angewandte Statistik der Johannes Kepler Universität Linz die Ergebnisqualität, Erfolgsrate und Patientensicherheit bei der ERCP in Österreich anhand von derzeit 28 319 gesammelten Untersuchungen.Die teilnehmenden Zentren mit unterschiedlicher ERCP-Frequenz und Untersucherzahl können so anhand des Vergleichs den gepoolten Benchmark-Daten individuelle Probleme in Hinblick auf Erfolgs-, Sondierungs- und Komplikationsraten (3,9 % Post-ERCP-Pankreatitiden, 3,8 % Blutungen, 0,6 % Perforationen, 1,2 % Cholangitiden, 1,0 % kardiopulmonale Komplikationen) erkennen und verbessern.
Genome Detective: an automated system for virus identification from high-throughput sequencing data
Authors: Vilsker Michael , Moosa Yumna , Nooij Sam , Fonseca Vagner , Ghysens Yoika , Dumon Korneel , Pauwels Raf , Alcantara Luiz Carlos , Vanden Eynden Ewout , Vandamme Anne-Mieke , Deforche Koen , de Oliveira Tulio 
Published: August 2018

Abstract

Summary
Genome Detective is an easy to use web-based software application that assembles the genomes of viruses quickly and accurately. The application uses a novel alignment method that constructs genomes by reference-based linking of de novo contigs by combining amino-acids and nucleotide scores. The software was optimized using synthetic datasets to represent the great diversity of virus genomes. The application was then validated with next generation sequencing data of hundreds of viruses. User time is minimal and it is limited to the time required to upload the data.

Availability and implementation
Available online: http://www.genomedetective.com/app/typingtool/virus/.

Supplementary information
Supplementary data are available at Bioinformatics online.
Health Locus of Control Is Associated With Physical Activity and Other Health Behaviors in Cardiac Patients
Authors: Mercer Darren A. , Ditto Blaine , Lavoie Kim L. , Campbell Tavis , Arsenault André , Bacon Simon L. 
Published: August 2018

Purpose:
Physical inactivity, smoking, and excessive alcohol use are well-recognized modifiable risk factors for cardiovascular disease (CVD), yet uptake of strategies to mitigate these poor health behaviors varies widely among patients with cardiovascular disease. Part of this variation may be explained by health locus of control (HLOC), defined as the extent to which individuals believe their health is a consequence of their own actions, chance, or the influence of others (eg, physicians).

Methods:
A total of 599 cardiac outpatients (30% female, 61.4 ± 9.4 y of age) completed the Multidimensional Health Locus of Control questionnaire and a structured health behavior questionnaire assessing physical activity, smoking, and alcohol use, at baseline and a 4-y follow-up. Relationships between health behaviors and HLOC were assessed cross-sectionally and longitudinally using general linear models and logistic regression models adjusting for medical and sociodemographic factors.

Results:
Higher Internal HLOC was found to be associated with higher levels of leisure time physical activity (LTPA) (β = .21, P = .0008), while lower Internal HLOC was associated with decreasing levels of alcohol consumption over time (β = .26, P = .03). Increasing Chance HLOC was related to lower levels of leisure time physical activity (β = −.15, P = .047) and increased likelihood of being a smoker (β = .10, P = .01), and increasing physician HLOC was associated with decreased likelihood of being a smoker (β = −.17, P = .01).

Conclusions:
Associations between HLOC and multiple health behaviors were observed in a large sample of cardiac outpatients. Results suggest that assessing and targeting HLOC beliefs of cardiac patients may be clinically relevant for behavior change in settings, such as in rehabilitation programs where behavior change is a goal.
CENTRAL RETINAL ARTERY OCCLUSION WITH CILIORETINAL ARTERY SPARING AFTER LASER-ASSISTED IN SITU KERATOMILEUSIS
Authors: Francis Andrew W. , Zhu Ivy , Borirakchanyavat Sidhiporn , Schwartz Daniel M. , Hwang David G. 
Published: August 2018

Purpose:
To report a central retinal artery occlusion with cilioretinal artery sparing in a 48-year-old woman after laser-assisted in situ keratomileusis surgery.

Methods:
Case history and clinical examination including best-corrected visual acuity, serum markers, slit-lamp biomicroscopy, indirect ophthalmoscopy, fundus photography, fluorescein angiography, and optical coherence tomography.

Results:
A 48-year-old woman underwent routine laser-assisted in situ keratomileusis surgery in both eyes. On postoperative Day 1, vision was 20/20 in both eyes with full visual fields by confrontation. Eight hours after being examined, she reported photopsias and a new visual field defect in the right eye . Visual acuity was 20/40, pinhole 20/20 in the right eye, with restriction of visual field by confrontation. Dilated fundus examination revealed retinal whitening in all quadrants with sparing of the fovea along the distribution of a perfused cilioretinal artery. Optical coherence tomography showed an intact foveal depression with inner retinal layer hyperreflectivity outside the region of the perfused cilioretinal artery. Fluorescein angiography revealed sectoral nonperfusion of the posterior pole with macular sparing along the patent cilioretinal artery. Hypercoagulable workup, carotid imaging, and magnetic resonance imaging of the brain were unremarkable.

Conclusion:
This is the first report of a central retinal artery occlusion with cilioretinal artery sparing occurring on postoperative Day 1 after laser-assisted in situ keratomileusis surgery.