bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of a titanium plate for novel fixation of a distal radius fracture in an Italian Greyhound
Authors: Syrcle J.A. , Cook J.L. 
Published: March 2018

SummaryA three-year-old Italian Greyhound was admitted for an acute none-weight-bearing lameness of the left forelimb, due to a closed transverse fracture of the distal radius and ulna. Open reduction with internal fixation of the radius fracture was performed and the fracture was stabilized using a 2.0-mm 5-hole titanium Y-plate. External coaptation with a caudal splint was added for additional support. The fracture healed with clinical and radiographic union noted eight weeks postoperatively. Neither implant failure nor stress-protection osteopaenia occured during the 13-month follow-up period. The dog returned to full function without complications. Using this method, five additional dogs were also treated successfully.
Radiographic evaluation of mechanically tested cemented total hip arthroplasty femoral components retrieved post-mortem
Authors: Pluhar E. , Skurla C. P. , Egger E. L. , James S. P. , Frankel D. J. 
Published: March 2018

SummaryGuidelines for assessing total hip arthroplasty (THA) radiographs for femoral implant stability have not been published; therefore, often the determination is subjective. The aim of this study was to identify radiographic criteria for veterinary clinicians to use when evaluating radiographs for femoral implant stability. Specific objectives were to: identify radiographic features associated with canine THA femoral implant loosening, evaluate whether technical recommendations for human femoral component implantation apply to dogs, and evaluate the effectiveness of radiographs for identifying canine THA implant loosening. Post-operative, follow-up, and post-mortem contact radiographs of canine implanted femora retrieved postmortem and mechanically tested for implant stability were evaluated. Based on the results, radiographic evaluation is not an effective means of assessing canine femoral implant stability; however, certain radiographic findings including implant retroversion, cement mantle cracks, or the appearance of cementmetal interface radiolucencies, may be indicative of implant loosening. It was also found that femoral implants completely surrounded by cement mantle of any thickness were less likely to loosen than those with an area lacking cement between the implant and bone. There was also a trend suggesting an association between inferior cement mantle quality and femoral implant loosening. In order to improve cement mantle quality and ensure that implants are completely surrounded by cement mantle, the use of modern cementing techniques is recommended.
Tibial tuberosity advancement in 65 canine stifles
Authors: Miller J. M. , Ober C. P. , Lanz O. I. , Martin R. A. , Shires P. K. , Hoffmann D. E. 
Published: March 2018

SummaryThe tibial tuberosity advancement (TTA) procedure was developed to treat dogs with cranial cruciate ligament deficient stifles. A retrospective, descriptive study was performed on 57 dogs that underwent unilateral or bilateral TTA. Medical records were reviewed and pre-, postoperative and follow-up radiographs were evaluated for patellar ligament-tibial plateau angle (α), distance of the tibial tuberosity advancement and progression of degenerative joint disease. A questionnaire was sent to all owners to obtain their assessment of the procedural outcome. Sixty-five stifles in 57 dogs received a TTA. Mean age was 5.2 ± 2.5 years while mean weight was 39.7 ± 11.9 kg. Eighteen breeds were represented with Labrador retrievers and mixed breeds predominating. The mean duration of lameness prior to surgery was 6.2 ± 6.7 months, with a median lameness score of 3/4. Fifty-nine percent of cases encountered complications, the majority of which were minor. Major post-operative complications were uncommon but consisted of implant failure, tibial crest displacement and medial meniscal tears. The mean radiographic preoperative angle α was 100°, while the postoperative was 95.5°. Mean osteoarthrosis scores were significantly different between preoperative and follow-up radiographs with 67% of cases showing radiographic progression. Seventy percent of owners responded to the survey with overall outcome considered good to excellent in 90%. Activity level was improved in 90% of responses. TTA subjectively appears to be a useful alternative in the management of cranial cruciate ligament disease. Few severe complications were encountered. Good clinical outcome and owner satisfaction was reported with the procedure in this set of cases.
Utilization of a Dynamic Stifle Flexion Apparatus in Preventing Recurrence of Quadriceps Contracture: A Clinical Report
Authors: McDonald D. E. , Hulse D. A. , Wilkens B. E. 
Published: March 2018

SummaryQuadriceps contracture is a well documented postoperative complication of femoral fractures, especially in immature animals. Historically, management of this condition has been difficult, and long-term prognosis has usually been poor. This case documents surgical correction of the quad-riceps contracture in a mixed breed dog, and the use of a dynamic stifle flexion apparatus postoperatively. The purpose of the dynamic stifle flexion apparatus was to encourage early, active use of the affected limb by the patient. Concurrent passive flexion and extension exercises, by the owner, were an integral component in preventing recurrence of pathological contracture of the quadriceps muscle group.Quadriceps contracture of the left quadriceps muscle group was diagnosed in a sixteen-week-old mixed breed dog twelve weeks following repair of a femur fracture. Surgical correction of the contracture was undertaken, and a dynamic stifle flexion device was applied to prevent future recurrence of the contracture. Sixteen weeks following repair, function had returned to the limb with stifle and hock ranges of motion approaching the values measured immediately postoperatively.
Effects of Tendon Splitting on Experimentally-Induced Acute Equine Tendinitis
Authors: Bramlage L. R. , Bailey M. , Bertone A. L. , Weisbrode S. E. , Henninger R. W. 
Published: March 2018

SummaryThe objective of this study was to compare the early phases of healing between surgically split and unsplit (control) tendons in a superficial digital flexor tendinitis model. Tendinitis was induced in both forelimbs of six horses by injection with collagenase. One tendon from each horse was randomly chosen to undergo tendon splitting. In six horses, the tendons were evaluated by ultrasonography before (week 0) and after (week 1) the onset of tendinitis and at weeks two, three, and four following tendon splitting. Three horses were euthanatized at the end of week four. Three horses were maintained for an additional month and evaluated at week eight before euthanasia. Following euthanasia, microangiographic and histologic evaluations were performed. Ultrasonographic evaluation revealed a significant (p <0.05) decrease in mean tendon lesion area in the split tendons when compared to the controls at weeks three, four, and eight. By week eight, all lesions had resolved in the split but not the control tendons. Mean lesion grade was lower in the split tendons at weeks two, three, four, and eight. Tendon area was similar (p >0.05) between groups at all periods after surgery. There was a more mature vascular pattern and greater peritendinous vascular response in the split tendons compared to control tendons. Histological examination under plain and polarized light revealed more normal collagen orientation and wave formation in the repair tissue in the split tendons at weeks four and eight. The fibroblast nuclei density was significantly (p <0.05) lower in the split tendons at week eight. These findings suggest that during the time period of this study, tendon splitting results in a more rapid decrease in lesion size and superior repair tissue organization when compared to controls.In a collagenase-induced tendinitis model, tendon splitting was shown to result in a greater reduction in tendon lesion size and superior repair tissue organization when compared to control tendons.
Results of Treatment of Degenerative Lumbosacral Stenosis in Dogs by Exploration and Excision
Authors: Selcer Barbara A. , Oliver J. E. , Chambers J. N. 
Published: March 2018

Twenty-six dogs with degenerative stenosis of the lumbosacral spinal canal were treated by excision of the encroaching tissues. The most common singular lesion was type II disc herniation.All of the dogs responded favourably to the surgery, but the dogs with only pain and lameness before surgery generally did better than those with incontinence.Laminectomy and excision of the encroaching degenerated tissues is an effective and relatively uncomplicated method of treating lumbosacral stenosis in dogs.
Multiple Enchondromatosis in the Dog
Authors: Krauser K. , Schwartz-Porsche Dorothea , Putzer-Brenig Afra v. , Matis Ulrike 
Published: March 2018

SummaryThe clinical and radiological findings of three related Miniature Poodles with multiple enchondromatosis (Ollier’s disease) are presented. Persisting, in part ossified growth plate cartilage foci were found bilaterally in the humerus, radius, ulna, femur, tibia and fibula of each dog and in one dog in some metacarpal and metatarsal bones. The ribs and many vertebral bodies were also affected. There was evidently no bone formation in the sternebrae. All three dogs first attracted attention at the ages of four to six months, with spontaneous bilateral femoral neck fractures. The mode of inheritance of the condition is not yet clear, but based on the known pedigree data a dominant effect appears unlikely.
Osteochondritis Dissecans of the Medial Trochlear Ridge of the Talus in the Dog
Authors: Spaulding K. A. , Braden T. D. , Breur G. J. 
Published: March 2018

SummaryThe medical records of 12 dogs with osteochondritis dissecans (OCD) of the medial trochlear ridge of the talus were reviewed. Long-term treatment results were obtained from client questionnaires and clinical and radiographic re-examinations. After a mean follow-up time of 52 months, only three of 12 dogs treated for OCD of the medial trochlear ridge of the talus had regained full function of the affected joint(s). In all cases available for radiographic re-examination, osteoarthritic changes had progressed. The medial approach to the hock joint by osteotomy of the medial malleolus was associated with a high complication rate.A meta-analysis of 38 cases (55 joints) of previous clinical studies and the present clinical study indicated that the Labrador Retriever and the Rottweiler were the most frequently affected breeds. Seventy-five percent of the affected Labrador Retrievers and Bull Terriers had bilateral involvement. The data suggested that in young dogs with an acute lameness, due to osteochondritis dissecans of the medial trochlear ridge in the talus, treatment resulted in 18% of the affected limbs in a normal limb function, in 27% in an intermittent lameness and in 55% in a chronic lameness. In dogs with a more chronic lameness, treatment results were better and approximately 40% of the affected limbs returned to normal function, while chronic lameness following treatment was unusual. In dogs older than a year at the time of treatment initiation, treatment became less successful because of the presence of severe osteoarthritic changes before treatment. Only 24% obtained normal limb function following treatment, while in 42% of the dogs treatment resulted in a chronic lameness.
Evaluation of Hip Joint Congruence and Range of Motion Before and After Triple Pelvic Osteotomy
Authors: Miller C. W. , McLaughlin R. 
Published: March 2018

SummaryFifteen dogs undergoing triple pelvic osteotomy (TPO) for bilateral hip dysplasia were evaluated prospectively. Ten dogs were treated bilaterally, five dogs were treated unilaterally. Hip joint palpation, radiography and goniometry were performed before surgery and at 5, 10, 15, and 28 weeks after surgery.Joint congruence was significantly improved palpably and radiographically in treated hips while congruence deteriorated in untreated hips. Improvement in congruence was minimal after the five week evaluation. Goniometric measurements were variable but range of motion was generally not decreased after TPO.
Integrierte Versorgung Schizophrenie der AOK Niedersachsen
Authors: Poweleit N. , Preugschat F. 
Published: March 2018

ZusammenfassungGegenstand und Ziel: Der Beitrag zeigt auf, wie die positiven Erfahrungen aus regionalen Selektivverträgen in der psychiatrischen Versorgung genutzt worden sind, um daraus ein niedersachsenweites Behandlungsangebot zu entwickeln. Es werden die Herausforderungen bei der Umsetzung betrachtet und aufgezeigt, mit welchen Erfolgsfaktoren eine flächendeckende Versorgung realisiert werden kann.Material und Methode: Der Beitrag basiert auf Ergebnissen aus den Pilotvorhaben, eigenen Erfahrungen beim Aufbau und der Umsetzung der Integrierten Versorgung Schizophrenie in Niedersachsen sowie von Rückmeldungen der an der Versorgung beteiligten Fachärzte, Fachkrankenpflegern und Angehörigenvertretern.Ergebnisse: Die Versorgungsstruktur ist über ein Flächenland wie Niedersachsen sehr heterogen ausgeprägt. Bei der Umsetzung eines landesweiten Versorgungsmodells müssen die regionalen Besonderheiten berücksichtigt werden und ein enger Kontakt zu den regionalen Verbünden aufgebaut werden.Schlussfolgerungen: Die Initiative zur Integrierten Versorgung Schizophrenie in Niedersachsen zeigt auf, dass es gut möglich ist, positive Erfahrungen aus kleinen Pilotierungsvorhaben auf ein ganzes Bundesland auszuweiten. Die wesentliche Erkenntnis ist, dass es Zeit braucht, um die Versorgungsstrukturen und ein auf den Patienten zentriertes Behandlungskonzept auf zu bauen. Die ersten positiven Reaktionen der teilnehmenden Patienten zeigen, dass der richtige Weg gewählt worden ist.
The International Partnership for Health Informatics Education
Authors: Gardner R. M. , Gatewood L. C. , Haux R. , Schmidt D. , Wetter T. , Jaspers M. W. M. 
Published: March 2018

Summary

Objectives:
To inform the medical and health informatics community on the rational, goals, and the achievements of the International Partnership for Health Informatics Education – IPHIE, (IΦE), that was established at six universities in 1999.

Methods:
We elaborate on the overall goals of IΦE and describe the current state of affairs: the activities undertaken and faculty and student experience related to these activities. In addition we outline the lessons we have learned over these past six years and our plans for the future.

Results:
IΦE members first started to collaborate by supporting and encouraging the exchange of talented students and faculty and by establishing joint master classes for honors students. Following the success of these activities, new initiatives were undertaken such as the organization of student workshops at medical informatics conferences and a joint course on strategic information management in hospitals in Europe.

Conclusions:
International partnerships such as IΦE take time to establish, and, if they are to be successful, maintaining leadership continuity is critically important. We are convinced that IΦE promotes professionalism of future medical informatics specialists. There will be a continuing growth of globalization in higher education. It will therefore become increasingly important to offer educational programs with international components.
Integrated Software Suite for Magnetocardio-graphic Data Analysis
Authors: Mantini D. , Merlino B. , Reale M. , Di Luzio S. , Romani G. L. , Comani S. 
Published: March 2018

Summary

Objectives:
This paper describes an integrated software suite (ISS) for the processing of magnetocardiographic (MCG) recordings obtained with super-conducting multi-channel systems having different characteristics. We aimed to develop a highly flexible suite including toolboxes for current MCG applications, organized consistently with an open architecture that allows function integrations and upgrades with minimal modifications; the suite was designed for the compliance not only of physicists and engineers but also of physicians, who have a different professional profile and are accustomed to retrieve information in different ways.

Methods:
The MCG-ISS was designed to work with all common graphical user interface operative systems. MATLAB was chosen as the interactive programming environment (IPE), and the software was developed to achieve usability, interactivity, reliability, modularity, expansibility, interoperability, adaptability and graphics style tailoring. Three users, already experienced in MCG data analysis, have intensively tested MCG-ISS for six months. A great amount of MCG data on normal subjects and patients was used to assess software performances in terms of user compliance and confidence and total analysis time.

Results:
The proposed suite is an all-in-one analysis tool that succeeded in speeding MCG data analysis up to about 55% with respect to standard reference routines; it consequently enhanced analysis performance and user compliance.

Conclusions:
Those results, together with the MCG-ISS advantage of being independent on the acquisition system, suggest that software suites like the proposed one could uphold a wider diffusion of MCG as a diagnostic tool in the clinical setting.
The Digital Pen and Paper
Authors: Landau R. , Rutschmann O. , Simon J. , Lovis C. , Despont-Gros C. 
Published: March 2018

Summary

Objectives:
To evaluate the efficiency and acceptance of digital pen and paper technology for real-time clinical data acquisition.

Methods:
A prospective interventional unblinded study involving consecutive patients in two clinical settings during a defined time-frame was proposed. The first trial was designed as a stress test to evaluate acceptance in a workload-intensive environment. Acceptance was assessed using observations and a satisfaction questionnaire. The second trial was intended to determine the reliability of data acquisition in a controlled environment. Reliability was assessed by comparing the performance of the digital pen against scanner analysis and a double human blinded acquisition.

Results:
Overall, users were satisfied with the use of the digital pen (median 3 on a Likert-scale (–5, 5)). Without any specific user training, successful data acquisition was greater than 80%. Use of this technology required less adaptation than standard computer devices, and was easy to learn and use. Ergonomic problems shaded the perception of the technology by inducing an increased cognitive load. Digitalized data was missing either because of a bug or due to lack of data validation. The reliability obtained with the digital pen was significantly lower to that obtained with the scanner.

Conclusions:
Natural technology such as the digital pen proved to be a good tool in stressful clinical environments without interfering with the normal workload or increasing the time for data acquisition. However, in order to improve quality of data acquisition, designing acquisition forms specifically for the use of digital pens is of paramount importance.
The Challenge of Ubiquitous Computing in Health Care: Technology, Concepts and Solutions
Authors: Ammenwerth E. , Brigl B. , Knaup P. , Lang E. , Pilgram R. , Pfeifer B. , Ruderich F. , Wolff A. C. , Haux R. , Kulikowski C. , Bott O. J. 
Published: March 2018

Summary

Objectives:
To review recent research efforts in the field of ubiquitous computing in health care. To identify current research trends and further challenges for medical informatics.

Methods:
Analysis of the contents of the Yearbook on Medical Informatics 2005 of the International Medical Informatics Association (IMIA).

Results:
The Yearbook of Medical Informatics 2005 includes 34 original papers selected from 22 peer-reviewed scientific journals related to several distinct research areas: health and clinical management, patient records, health information systems, medical signal processing and biomedical imaging, decision support, knowledge representation and management, education and consumer informatics as well as bioinformatics. A special section on ubiquitous health care systems is devoted to recent developments in the application of ubiquitous computing in health care. Besides additional synoptical reviews of each of the sections the Yearbook includes invited reviews concerning E-Health strategies, primary care informatics and wearable healthcare.

Conclusions:
Several publications demonstrate the potential of ubiquitous computing to enhance effectiveness of health services delivery and organization.But ubiquitous computing is also a societal challenge, caused by the surrounding but unobtrusive character of this technology. Contributions from nearly all of the established sub-disciplines of medical informatics are demanded to turn the visions of this promising new research field into reality.
Quality-assured Efficient Engineering of Feedforward Neural Networks (QUEEN)
Authors: Hensler K. , Waschulzik T. , Mönig S. P. , Maruyama K. , Hölscher A. H. , Bollschweiler E. 
Published: March 2018

Summary

Objectives:
Lymph node metastasis (LNM) is an important prognostic indicator in patients with gastric carcinoma. However, the methods that have been established for preoperative diagnosis of LNM show insufficient accuracy.

Methods:
This study describes the use of the QUality Assured Efficient Engineering of Feedforward Neural Networks with Supervised Learning (QUEEN) technique to attempt optimization of the preoperative diagnosis of lymph node metastasis in patients with gastric carcinoma. The results were compared with the Maruyama Diagnostic System (MDS) for preoperative prediction of LNM, established at the National Cancer Center in Tokyo.

Results:
QUEEN is able to extract predictive variables from a case-based database. The combination of a development method, a special type of neural network and the corresponding encoding yielded an accuracy of 72.73%, which is notably higher than that of the MDS. Our system produced a nearly ten per cent higher sensitivity and around eighteen per cent higher specificity than MDS.

Conclusion:
Our results show that QUEEN is a reasonable method for the development of ANNs. We used the QUEEN system for prediction of LNM in gastric cancer. This system may allow more meaningful preoperative planning by gastric surgeons.