bluuebunny/crossref_metadata_2025_split huggingface dataset:
Importance of Nongovernmental Organizations for the Establishment of a Successful Hematopoietic Stem-Cell Transplantation Program in a Developing Country
Authors: Rivera Franco Monica M. , Leon Rodriguez Eucario 
Published: February 2018

Purpose In low- and middle-income countries with limited resources, the success of a hematopoietic stem-cell transplantation (HSCT) program relies directly on its affordability while obtaining similar outcomes to developed regions. The objective of this study was to describe the experience of a tertiary/referral center in Mexico City performing HSCT with the subsidy of a nongovernmental organization (NGO). Patients and Methods We performed a retrospective analysis including 146 patients who underwent HSCT at the National Institutes of Health Sciences and Nutrition Salvador Zubiran and were subsidized by the NGO Unidos. Results Seventy-five patients (51%) and 71 patients (49%) underwent autologous and allogeneic HSCT, respectively. The median age was 30 years, 56% did not obtain a bachelor’s degree, 79% had a low socioeconomic level, and 75% were unemployed. None had any health coverage. According to the real patient out-of-pocket expense, the subsidy by Unidos corresponded to 88% and 72% in autologous and allogeneic HSCT, respectively. Conclusion Our results highlight that undergoing an HSCT was feasible for vulnerable patients because of the subsidy of medications and chemotherapy by Unidos. Therefore, creating NGOs in developing countries is important to provide complex medical procedures, such as HSCT, at limited-resource centers to underserved populations while obtaining good outcomes.
Yeast cells contain a heterogeneous population of peroxisomes that segregate asymmetrically during cell division
Authors: Choudhry Sanjeev Kumar , de Boer Rinse , van der Klei Ida J. 
Published: February 2018

ABSTRACT
Here, we used fluorescence microscopy and a peroxisome-targeted tandem fluorescent protein timer to determine the relative age of peroxisomes in yeast. Our data indicate that yeast cells contain a heterogeneous population of relatively old and young peroxisomes. During budding, the peroxisome retention factor inheritance of peroxisomes protein 1 (Inp1) selectively associates to the older organelles, which are retained in the mother cells. Inp2, a protein required for transport of peroxisomes to the bud, preferentially associates to younger organelles. Using a microfluidics device, we demonstrate that the selective segregation of younger peroxisomes to the buds is carefully maintained during multiple budding events. The replicative lifespan of mother cells increased upon deletion of INP2, which resulted in the retention of all organelles in mother cells. These data suggest that, in wild-type yeast, transport of aged and deteriorated peroxisomes to the bud is prevented, whereas the young and vital organelles are preferably transported to the newly forming buds.
Accuracy and precision of manual segmentation of the maxillary sinus in MR images—a method study
Authors: Andersen Tobias N , Darvann Tron A , Murakami Shumei , Larsen Per , Senda Yurie , Bilde Anders , Buchwald Christian v , Kreiborg Sven 
Published: February 2018

Objective:
To assess the accuracy and precision of segmentation of the maxillary sinus in MR images to evaluate the potential usefulness of this modality in longitudinal studies of sinus development.

Methods:
A total of 15 healthy subjects who had been both craniofacial CT and MR scanned were included and the 30 maxillary sinus volumes were evaluated using segmentation. Two of the authors did segmentation of MRI and one of these authors did double segmentation. Agreement in results between CT and MRI as well as inter- and intraexaminer errors were evaluated by statistical and three-dimensional analysis.

Results:
The intraclass correlation coefficient for volume measurements for both method error, inter- and intraexaminer agreement were &gt; 0.9 [maximal 95% confidence interval of 0.989–0.997, p &lt; 0.001] and the limit of agreement for all parameters were &lt; 5.1%. Segmentation errors were quantified in terms of overlap [Dice Coefficient (DICE) &gt; 0.9 = excellent agreement] and border distance [95% percentile Hausdorff Distance (HD) &lt; 2 mm = acceptable agreement]. The results were replicable and not influenced by systematic errors.

Conclusion:
We found a high accuracy and precision of manual segmentation of the maxillary sinus in MR images. The largest mean errors were found close to the orbit and the teeth.

Advances in knowledge:
MRI can be used for 3D models of the paranasal sinuses with equally good results as CT and allows longitudinal follow-up of sinus development.
Perspectiva indigenista en la música metal de Argentina
Authors: Belén Calvo Manuela 
Published: February 2018

Resumen
El indigenismo fue una corriente literaria que se originó en la década de 1920 en Perú y que se desarrolló en varios países andinos, incluso en la Argentina. Aquí la literatura indigenista fue una reacción a los ideales hegemónicos de civilización y barbarie con los cuales se asesinó y sometió a los pueblos originarios. A partir de la década de 1980, gran cantidad de bandas de música metal argentina adoptan esa misma postura. Este artículo tiene como objetivo examinar la forma en que la música metal de Argentina usa una lógica dualista para defender al referente aborigen y condenar al extranjero, utilizando retóricas propias del metal, externas al mundo indígena y provenientes del contexto de la globalización y el capitalismo. Esta reflexión se basa en el análisis sociosemiótico de las producciones de algunas bandas.
Morbo ancestral: Reformulando la cultural local a través de la música metal en Puerto Rico
Authors: Rivera-Segarra Eliut , Varas-Díaz Nelson , Mendoza Sigrid , Díaz Xaymara 
Published: February 2018

Resumen
La integración de la cultura local al metal hecho en Puerto Rico ha ganado interés y atención en las pasadas décadas. Durante la década de los 90 el metal, aún visto como una entidad foránea y estadounidense, integraba la cultura puertorriqueña a su música de forma celebratoria. Esto ha cambiado recientemente y hoy se experimenta una integración temática a través de líricas y arte visual que se distancian de dichas estrategias celebratorias y asumen una perspectiva más crítica sobre la cultura local. El objetivo de este trabajo fue documentar cómo la comunidad metalera de Puerto Rico ha integrado la cultura local al metal de modo crítico mediante una reformulación de los elementos locales. Implementamos un estudio de caso con técnicas de entrevista y análisis de documentos visuales. Aunque usualmente las producciones culturales son recibidas irreflexivamente y de manera celebratoria, recientemente el metal produce música y arte con elementos culturales que critican dicho acercamiento y destacan críticamente el modo en que las producciones culturales también aluden a la morbosidad y a lo oscuro. Examinamos dicha caracterización a través de la figura del vejigante usada en festivales culturales y en las artes plásticas en Puerto Rico. Discutimos el modo en que el metal utiliza la producción cultural como reflejo de un lado oscuro de lo social en Puerto Rico; un tema del cual la mayor parte de la población preferiría no hablar.
Letters, cassette tapes and zines: The circulation of Brazilian heavy metal as a gift system
Authors: dos Santos Silva Melina Aparecida 
Published: February 2018

Abstract
The article addresses cultural exchanges in the Brazilian metal scene and the social practices around materialities such as letters, cassette tapes and fanzines. The exchange of items between headbangers contributed to the globalization of metal and continued over the 1990s and 2000s, in peripheral territories, like Brazil, even with the presence of the Internet. The article is based on a questionnaire administered via social network groups dedicated to Brazilian metal and collectors of cassette tapes and fanzines. The circulation of metal in Brazil is explained from the paradigm of the gift, proposed by Marcel Mauss and others. Our purpose is to highlight the construction of identities and social bonds offered by this cultural exchange.
A new target for the treatment of endometrium cancer by succinic acid
Authors: Iplik Elif Sinem , Catmakas Tolga , Cakmakoglu Bedia 
Published: February 2018

Endometrium cancer is the most common invasive gynecologic malignancy in developed countries. Succinic acid (CO2HCH2-CH2CO2H) is a type of dibasic acid that has uncolored crystal. Succinic acid is used in bakery products and aromatized products. It is naturally found in some vegetables. Succinic acid has no adverse effects because it is metabolized by body cells and has a role in the tricarboxylic acid cycle (TCA) as a cycle media component. The TCA cycle and its enzyme components have some crucial roles for basal cell metabolism. Any mistakes, concentration differences in product, or enzyme deficiencies are important within the cell this cycle. In this proposal project, we aimed to investigate the effect of succinic acid at different doses and at different times in an endometrial cancer cell line. The study was performed using methods that determine for apoptosis (for cytotoxicity, WST-1, for caspase enzyme activity, Caspase 3/BCA; apoptotic determination using flow cytometry; Annexin V; to understand mitochondrial membrane potential; JC-1). The results showed that 5 and 10 µM concentration of succinic acid resulted in apoptosis in endometrium cancer; no such effect was seen in the control cell line, which comprised healthy lung cells. According to our results, it is thought that succinic acid would be effective for the treatment of endometrial cancer cell lines, thus providing new data for other areas of cancer research.
Subaru and Salt Spectroscopy of Chemically Peculiar Hot Subdwarfs
Authors: Jeffery C. Simon , Neelamkodan Naslim , Woolf Vincent M. , Crawford Steven M. , Østensen Roy H. 
Published: February 2018

Abstract
The majority of hot subdwarfs lie on or close to the helium main-sequence. Many have hydrogen-rich surfaces, but a substantial fraction of the hotter subdwarfs have hydrogen-depleted or hydrogen-deficient surfaces. Amongst the former, three were known to show extraordinary overabundances of heavy elements including zirconium and lead. Using Subaru/HDS,we commenced a high-resolution survey of hydrogen-depleted subdwarfs to discover new members of the class. UVO 0825+15, was found to exhibit strong lead lines, to be an intrinsic variable in K2 field 5, and to have a relatively high space motion. Two other lead-rich subdwarfs have been found in the Subaru sample. A much wider survey is in progress using SALT/HRS. Discoveries so far include one extreme helium star similar to V652 Her, and an intermediate helium star with possible comparison to HD144941. Analyses of the hotter and more compact members of the sample are continuing.
HST spectroscopy of chemically peculiar hot subdwarfs: PG 0909+276 and UVO0512–08
Authors: Wild James , Jeffery Christopher Simon 
Published: February 2018

Abstract
High-resolution ultraviolet spectroscopy of two chemically peculiar hot subdwarfs, PG 0909+276 and UVO0512-08, has been obtained using the Hubble Space Telescope. Chemical abundances in the stars’ atmospheres were measured from previous optical spectra and from the new ultraviolet observations. Iron-group metals, including cobalt, copper and zinc, are highly enriched relative to typical subdwarf B (sdB) stars. Lead is also enriched, but with an abundance similar to other sdB stars. The surface chemistry of these two stars is quite distinct from both hydrogen-rich normal sdB stars and also from the intermediate helium-rich sdB stars which show heavy-element superabundances. A full explanation for exotic chemistries in hot subdwarfs remains elusive.
Group actions, non-Kähler complex manifolds and SKT structures
Authors: Poddar Mainak , Thakur Ajay Singh 
Published: February 2018

Abstract
We give a construction of integrable complex structures on the total space of a smooth principal bundle over a complex manifold, with an even dimensional compact Lie group as structure group, under certain conditions. This generalizes the constructions of complex structure on compact Lie groups by Samelson and Wang, and on principal torus bundles by Calabi-Eckmann and others. It also yields large classes of new examples of non-Kähler compact complex manifolds. Moreover, under suitable restrictions on the base manifold, the structure group, and characteristic classes, the total space of the principal bundle admits SKT metrics. This generalizes recent results of Grantcharov et al. We study the Picard group and the algebraic dimension of the total space in some cases. We also use a slightly generalized version of the construction to obtain (non-Kähler) complex structures on tangential frame bundles of complex orbifolds.
Contact manifolds, Lagrangian Grassmannians and PDEs
Authors: Eshkobilov Olimjon , Manno Gianni , Moreno Giovanni , Sagerschnig Katja 
Published: February 2018

Abstract
In this paper we review a geometric approach to PDEs. We mainly focus on scalar PDEs in n independent variables and one dependent variable of order one and two, by insisting on the underlying (2n + 1)-dimensional contact manifold and the so-called Lagrangian Grassmannian bundle over the latter. This work is based on a Ph.D course given by two of the authors (G. M. and G. M.). As such, it was mainly designed as a quick introduction to the subject for graduate students. But also the more demanding reader will be gratified, thanks to the frequent references to current research topics and glimpses of higher-level mathematics, found mostly in the last sections.
Synthesis, physicochemical and catalytic properties of Ni/PrCeZrO catalysts for water-gas shift reaction
Authors: Larina Tatyana V. , Fedorova Yulia E. , Krieger Tamara A. , Ishchenko Arcady V. , Glazneva Tatiana S. , Sadovskaya Ekaterina M. , Eremeev Nikita F. , Sadykov Vladislav A. 
Published: February 2018

AbstractMixed nanocrystalline ceria-zirconia oxides doped with praseodymium containing 5, 7.5, 10, and 12.5 wt. % nickel were prepared by the incipient wetness impregnation of the oxide support. Complex physicochemical characterization by X-ray diffraction analysis, ultraviolet-visible diffuse reflectance spectroscopy, high resolution transmission electron microscopy and Fourier-transform infrared spectroscopy of adsorbed CO revealed that the nickelcontaining samples are comprised of a solid solution of praseodymium, cerium and zirconium oxides with the fluorite structure as well as nickel oxide particles with a size up to 100 nm. All prepared nanocomposite catalysts show a high catalytic activity in the water-gas shift reaction. The optimum content of nickel in the catalyst providing the maximum activity was found to be 10 wt. %. A high oxygen mobility in these catalysts estimated by the temperature-programmed oxygen isotope heteroexchange with C18O2 provides required coking stability. To eliminate local overheating of the catalyst and decrease the pressure drop in the reactor, as required for further up-scaling, the active component was supported on a metal plate made of Ni-Al foam alloy. At a fixed contact time, the same level of CO conversion with a fraction of the active component was achieved with an approximately 50 wt% loading on the support.
Design and Implementation of Electro-Optic 2×2 Switch and Optical Gates using MZI
Authors: Kaur Gurjit , Rani Neha , Parasher Yaman , Singh Prabhjot 
Published: February 2018

AbstractMZI switches are well-known devices for high speed communication applications. A lot of researchers have designed MZI switches by using lithium niobate and potassium niobate material. But the major problem of using these type of material includes high insertion losses and required high switching voltage. So, in this research paper we have designed a 2×2 electro-optic switch using optical waveguide designed with Titanium (Ti) diffused in Strontium barium niobate (SBNO3) material which can operate at wavelength of 1.3 um. Results show that the proposed structure gives better output in terms of extinction ratio (=29.9 db) as well as for insertion losses (≤0.018). Further, we have designed various optical gates i. e. XNOR, XOR and AND optical gates and their performance is also evaluated by varying electrode voltages. It is inferred from the results that the proposed model gives better results even in terms of output power which can be used for commercial purpose.
Sequential Testing with Uniformly Distributed Size
Authors: Anatolyev Stanislav , Kosenok Grigory 
Published: February 2018

Abstract
Sequential procedures for the testing for structural stability do not provide enough guidance on the shape of boundaries that are used to decide on acceptance or rejection, requiring only that the overall size of the test is asymptotically controlled. We introduce and motivate a reasonable criterion for the shape of boundaries which requires that the test size be uniformly distributed over the testing period. Under this criterion, we numerically construct boundaries for the most popular sequential tests that are characterized by a test statistic behaving asymptotically either as a Wiener process or Brownian bridge. We handle this problem both in the context of retrospecting a historical sample and in the context of monitoring newly arriving data. We tabulate the boundaries by fitting them to certain flexible yet parsimonious functional forms. Interesting patterns emerge in an illustrative application of sequential tests to the Phillips curve model.
Data Assimilation in a Multi-Scale Model
Authors: Hu Guannan , Franzke Christian L. E. 
Published: February 2018

AbstractData assimilation for multi-scale models is an important contemporary research topic. Especially the role of unresolved scales and model error in data assimilation needs to be systematically addressed. Here we examine these issues using the Ensemble Kalman filter (EnKF) with the two-level Lorenz-96 model as a conceptual prototype model of the multi-scale climate system. We use stochastic parameterization schemes to mitigate the model errors from the unresolved scales. Our results indicate that a third-order autoregressive process performs better than a first-order autoregressive process in the stochastic parameterization schemes, especially for the system with a large time-scale separation.Model errors can also arise from imprecise model parameters. We find that the accuracy of the analysis (an optimal estimate of a model state) is linearly correlated to the forcing error in the Lorenz-96 model. Furthermore, we propose novel observation strategies to deal with the fact that the dimension of the observations is much smaller than the model states. We also propose a new analog method to increase the size of the ensemble when its size is too small.
Genetic Programming Technique Applied for Flash-Flood Modelling Using Radar Rainfall Estimates
Authors: Dinu Cristian , Drobot Radu , Pricop Claudiu , Blidaru Tudor Viorel 
Published: February 2018

Abstract
The rainfall-runoff transformation is a highly complex dynamic process and the development of fast and robust modelling instruments has always been one of the most important topics for hydrology. Over time, a significant number of hydrological models have been developed with a clear trend towards a process-based approach. The downside of these types of models is the significant amount of data required for building the model and for the calibration process: in practice, the collection of all necessary data for such models proves to be a difficult task. In order to cope with this issue, various data-driven modelling techniques have been introduced for hydrological modelling as an alternative to more traditional approaches, on the basis of their capacity of mapping out complex relationships from observation data. Having the capacity to generate meaningful mathematical structures as results, genetic programming (GP) presents a high potential for rainfall-runoff modelling as a data-driven method. Using ground and radar rainfall observation, the aim of this study is to investigate the GP technique capability for modelling the rainfall-runoff process, taking into consideration a flash-flood event.
Cloud Computing and Internet of Things Concepts Applied on Buildings Data Analysis
Authors: Hebean Florin-Adrian , Caluianu Sorin 
Published: February 2018

Abstract
Used and developed initially for the IT industry, the Cloud computing and Internet of Things concepts are found at this moment in a lot of sectors of activity, building industry being one of them. These are defined like a global computing, monitoring and analyze network, which is composed of hardware and software resources, with the feature of allocating and dynamically relocating the shared resources, in accordance with user requirements. Data analysis and process optimization techniques based on these new concepts are used increasingly more in the buildings industry area, especially for an optimal operations of the buildings installations and also for increasing occupants comfort. The multitude of building data taken from HVAC sensor, from automation and control systems and from the other systems connected to the network are optimally managed by these new analysis techniques. Through analysis techniques can be identified and manage the issues the arise in operation of building installations like critical alarms, nonfunctional equipment, issues regarding the occupants comfort, for example the upper and lower temperature deviation to the set point and other issues related to equipment maintenance. In this study, a new approach regarding building control is presented and also a generalized methodology for applying data analysis to building services data is described. This methodology is then demonstrated using two case studies.
Genotype X Environment Interaction for Yield of Pickling Cucumber in 24 U.S. Environments
Authors: Dia Mahendra , Wehner Todd C. , Elmstrom Gary W. , Gabert August , Motes James E. , Staub Jack E. , Tolla Greg E. , Widders Irvin E. 
Published: February 2018

Abstract
Reliable yield performance is important in cucumber because seed companies prefer to market cultivars adapted to multiple rather than single regions of the U.S. Also, growers benefit by using a cultivar that performs well in many environments. Future performance of cultivars is also important. The objectives of the study were to (i) evaluate the yield of cucumber genotypes over successive years and in different locations, and (ii) identify cucumber genotypes with high stability for yield. A diverse set of 22 pickling genotypes was evaluated over 3 years (1986, 1987 and 1988) and in 7 locations across the United States. Yield traits were evaluated using once-over harvest and counting the number of fruit that were marketable, culled or oversize. Total yield, marketable yield (total minus culled fruit), early yield (number of oversize fruit), percent culls and fruit per plant were calculated. Data were analyzed with SASGxE and RGxE programs using SAS and R programming languages, respectively. There were strong effects of environment(E) as well as genotype(G) xE interaction for all traits. Genotypes ‘Regal F1’, ‘Calypso F1’, ‘Carolina F1’, ‘Gy 3’, ‘Gy 14’ and ‘Fremont F1’ had high marketable yield and medium to high stability for all traits. There was an advantage of hybrids over inbreds for trait performance. Hybrids fell into a single cluster with large prediction intervals. Based on the stability statistics and divisive clusters, it appears possible to breed stable cucumber genotypes with high yield. The genotype with highest performance for marketable yield, greatest stability for yield, lowest 1-R2 ratio value (diverse and representative) were ‘Marbel F1’ and Gy 14.