bluuebunny/crossref_metadata_2025_split huggingface dataset:
Food Insecurity and Psychological Distress Among Former and Current Smokers With Low Income
Authors: Kim-Mozeleski Jin E. , Tsoh Janice Y. 
Published: June 2018

Purpose: To examine how food insecurity and psychological distress interact in its association with smoking and to explore how food insecurity and psychological distress are associated with quitting smoking using quit ratio estimates. Design: Cross-sectional study. Setting: Data from the 2015 California Health Interview Survey. Participants: A total of 3007 lower income adults who have ever smoked. Measures: Ever smoking was defined as smoking 100+ cigarettes in the entire lifetime, with current smoking defined as smoking “every day” or “some days” and former smoking defined as smoking “not at all.” Psychological distress and food insecurity were measured by the 6-item K6 Psychological Distress Scale and the 6-item Food Security Survey Short Form, respectively. Analysis: Multiple logistic regression analysis was used to examine correlates of smoking status. Quit ratios (percentage of ever smokers who have quit) were calculated across study variables. Results: Reporting food insecurity with psychological distress was independently associated with lower odds of being a former smoker, compared to reporting food security without psychological distress. The quit ratio was lower among ever smokers reporting food insecurity with distress (41%) compared to ever smokers reporting food security without distress (63%). Conclusions: Specific conditions of impoverishment, such as food insecurity, interact with psychological distress in its association with continued smoking. Interventions to reduce socioeconomic disparities in smoking should consider the interacting role of food insecurity and psychological distress.
Field evaluation of onsite near real-time monitors for surface contamination by 5-fluorouracil
Authors: Smith Jerome P , Sammons Deborah , Robertson Shirley , Krieg Edward , Snawder John 
Published: June 2018

Objectives In order to produce near real-time onsite results to detect surface contamination by antineoplastic drugs, the National Institute for Occupational Safety and Health developed monitors for 5-fluorouracil, which use surface wiping and lateral flow immunoassay for measurement. The monitors were tested in the laboratory to assess the sensitivity of detection on laboratory-produced contaminated surfaces. A field evaluation to assess the capability of the monitors to make measurements in healthcare workplaces was carried out in collaboration with a medical device company and the results are presented in this report. Methods The 5-fluorouracil monitor was evaluated in areas where oncology drugs were prepared and administered to patients at five different hospitals. The levels of contamination measured with the monitors were compared to levels measured with liquid chromatography-tandem mass spectrometry. Results The 5-fluorouracil values measured with the liquid chromatography-tandem mass spectrometry ranged from 0 to over 200,000 ng/100 cm2. Measurements by the 5-fluorouracil monitors in the range 10–100 ng/100 cm2 correlated with the liquid chromatography-tandem mass spectrometry. Receiver operating characteristic curves developed for the data indicated that a positive limit of 22 ng/100 cm2 would give an acceptable level of false-positives while retaining most true-positive samples. If the liquid chromatography-tandem mass spectrometry measured greater than 100 ng/100 cm2, then the monitors also measured levels greater than 100 ng/100 cm2 for the majority of samples. Conclusion The data indicate that there are many areas in hospitals that are contaminated with 5-fluorouracil and the monitors will be useful in identifying this contamination.
Prospective Analysis of Patients with Metastatic Breast Cancer receiving Eribulin Mesylate as Second or More Lines of Chemotherapy: An Indian Experience
Authors: Srinivasa BJ , Lalkota Bhanu Prakash , Badarke Girish , Hazarika Diganta , Mohammad Nasiruddin , Sapkota Sulav , Khanderia Mansi , Tousif D , Rao Raghavendra , Ram Amritanshu , Patil Shekar , Naik Radheshyam 
Published: June 2018

Background: Eribulin mesylate is a non-taxane microtubule inhibitor which can be used after anthracycline and taxane treatment in patients with metastatic breast cancer (MBC). The purpose of this study was to investigate the efficacy and safety of eribulin monotherapy in heavily pretreated patients with MBC. Methods: In this study, a total of 45 eligible patients with MBC who received eribulin in HCG Cancer Speciality Center from November 2014 to March 2016 were prospectively analyzed. Breslow (generalized Wilcoxon) survival analysis was carried out for progression-free survival and for overall survival. Patients were excluded if they had not taken treatment for 3 cycles and defaulted/expired during the treatment. Results: In this study, median age of patients was 52 years. A total of 27 (60%) patients had estrogen receptor and progesterone receptor (PR) positive primary tumors, whereas HER2 was overexpressed or amplified in 7 (15.6%); a triple negative subtype was recorded in 13 patients (28.9%). Regarding toxicity, 30 patients (66.67%) tolerated treatment well and 3 patients (6.67%) got anemia, 6 patients (13.3%) experienced neutropenia, and 7 (15.62%) patients had neurological toxicity. About 14 (31.1%) patients showed PR, 12 (26.7%) patients had stable disease (SD), whereas 19 (42.25%) patients showed progression disease (PD). Response evaluation at 6 cycles was possible in 18 patients and revealed that 4 (22.5%) patients showed PR, 10 (55.5%) patients had SD, whereas 4 (22.2%) patients had PD. Progression-free survival of the overall study population was 3.95 months. Conclusions: Eribulin mesylate is efficacious and tolerable chemotherapy as second- and third-line treatment options for MBC.
Perception toward generic drug products: A cross-sectional study among undergraduate pharmacy students of the University of Nigeria
Authors: Chibueze Anosike , Abdulmuminu Isah , Nnanyelugo Ogechukwu Isiogugu , Amos Azubuike Ekwuofu 
Published: June 2018

Background Ever-rising cost of healthcare in resource-limited countries necessitates the use of generic medications. In Nigeria, no study has assessed the perception of student pharmacists about generic medications. Therefore, this study aimed to determine the perception of pharmacy students toward generic medicines. Methods A cross-sectional study was conducted using a 12-item questionnaire among 241 pharmacy students of the University of Nigeria. The instrument was distributed to and completed by penultimate and final year pharmacy students. Descriptive statistics was used to present students’ characteristics and responses. Chi-square test was used to determine an association between perception of generic medicines and the students’ socio-demographic variables. P values ≤0.05 were considered statistically significant. All statistical analyses were performed using SPSS version 20. Results More than 60% of the respondents agreed that branded and generic medicines are bioequivalent and therapeutically equivalent. About half of the students (48.0%) preferred branded medicines to generic medicines in severe conditions. Age of respondents [χ2 (12) =24.780, p = 0.016] and place of residence [χ2 (4) = 9.523, p = 0.049] were significantly associated with the statement that branded medicines are required to meet higher safety standards relative to generic medications. Conclusion Our findings suggest a breach in perception among pharmacy students toward generic medications. Further educational interventions to improve students’ knowledge of generic medicines are recommended.
One step endoscopic ultrasound guided management of pelvic abscesses: a case series
Authors: Zator Zachary , Klinge Matthew , Schraut Wolfgang , Tsung Allan , Khalid Asif 
Published: June 2018

Background: Endoscopic management of pelvic abscesses not amenable to percutaneous drainage has been described. The technique employs endoscopic ultrasound (EUS)-guided placement of stents or drains, which may require multiple procedures, is cumbersome and uncomfortable for the patient. We describe the successful management of these abscesses in a single step involving EUS-guided lavage and instillation of antibiotics. Methods: Six consecutive patients with seven symptomatic pelvic abscesses not amenable to percutaneous drainage were referred for EUS-guided drainage. The abscesses were aspirated with a 19-gauge needle under EUS guidance and serially lavaged with an equal aspirate to instillation volume of sterile saline until cleared of pus. The residual cavity was then instilled with gentamicin 40 mg/ml. Patients were followed clinically and radiographically with repeat computed tomography or magnetic resonance imaging. Results: All patients had rapid resolution of symptoms. The abscesses disappeared completely in four patients. One patient with recurrent diverticulitis and abscess had marked decrease in abscess size and inflammation to permit planned sigmoid resection. One patient with Crohn’s disease had clinical improvement and marked decrease in abscess size, permitting outpatient management of Crohn’s disease. Conclusions: EUS-guided lavage and instillation of antibiotics is a simple, one-step approach in the management of pelvic abscesses and may obviate the need for prolonged drain management and repeat procedures in select cases.
Osteoplastic Flap Without Obliteration: How I Do It
Authors: Banks Catherine G. , Garcia Jaime A. P. , Grayson Jessica , Yeon Cho Do , Woodworth Bradford A. 
Published: June 2018

Background The osteoplastic flap provides access to pathology of the frontal sinus and is often performed with obliteration, which can result in significant long-term complications. Objective To describe the authors’ approach to osteoplastic flap without obliteration. Methods Descriptive analysis. Results Osteoplastic flap without obliteration preserves frontal sinus function while permitting direct access to the frontal sinus. In this study, we demonstrate a combined nonobliterated approach, accessing the frontal sinus with a Draf III approach to remove a large frontal sinus osteoma. Conclusion The approach provides excellent exposure for large tumors not otherwise accessible via purely endoscopic procedures, permits improved surveillance, and minimizes long-term complications of obliterated sinuses.
Spinal neuraxial anaesthesia for caesarean section in a parturient with type I Arnold Chiari malformation and syringomyelia
Authors: Teo Miqi Mavis 
Published: June 2018

Introduction: Type 1 Arnold Chiari malformation is associated with prolapse of the cerebellar tonsils into or below the level of the foramen magnum and is usually diagnosed in adults. There are no current guidelines for the management of patients with a residual type I Arnold Chiari malformation, planned for a caesarean section under spinal neuraxial anaesthesia. The paucity in the literature on this topic presents as a management dilemma. Case report: We report a case of a term parturient with type 1 Arnold Chiari malformation, following surgical decompression 4 years earlier, with a residual syringomyelia that underwent an elective caesarean section under spinal neuraxial anaesthesia. Conclusion: This case highlights that multidisciplinary management and early anaesthetic consult are of paramount importance in the outcome of the patient, and that spinal neuraxial anaesthesia can be considered as a safe anaesthetic option.
Frontoethmoidal encephalocele in a cat
Authors: Woerde Dennis J , Hoffmann Karon L , Brown Narelle L 
Published: June 2018

Case summary An 11-month-old female neutered domestic shorthair cat presented for further investigation of a 1 month history of generalised tonic–clonic seizures. Physical examination revealed microphthalmia of the left eye and right-sided hemiparesis. MRI of the brain and cranial neck was performed using a 1.5-Tesla system. MRI revealed a left frontoethmoidal encephalocele and microphthalmia of the left eye. Conservative treatment with antiepileptic medication was elected. The cat was managed on phenobarbitone and levetiracetam. Seizures have remained well controlled 12 months post-diagnosis. Relevance and novel information This is the first known case report of a frontoethmoidal encephalocele in a cat. This case was presented to increase clinical awareness of this congenital malformation and as a differential diagnosis for any young cat that presents with seizures.
Skeletal maturity as injury risk factor in adolescent elite track and field athletes
Authors: Martínez Silván Daniel , Johnson Amanda , Tramullas Antonio 
Published: June 2018

Objectives: To establish skeletal age and maturity status in highly trained adolescent track and field athletes and to investigate the relationship between maturation status and different type of injuries. Methods: 72 adolescent track and field athletes from different athletic disciplines (long distance n=15, sprints n=16, jumps n=10, throws n=12, combined events n=9, non-specialized n=10) belonging to an elite sport academy full time between 2013 and 2016 were selected for the study. An electronic medical record for musculoskeletal injuries was designed according to international standards for athletics, and skeletal age and maturity status were determined at the beginning of each season using FELS method, athletes being defined as early matures (EM), late matures (LM) or normo-matures (Norm) according to the difference between chronological and skeletal age. Results: A total number of 195 injuries with an incidence of 7 injuries per 1000 h of training exposure were recorded in 72 athletes (15±1.7y, 169.5±9.9 cm, 61.4±17.9 kg, 215±64 training hours per season). A vast majority of athletes were early mature (EM=78%, Norm= 12%, LM= 10%). 98% of athletes in jumps, sprints, throws and combined events were EM, while a predominance of Norm (40%) and LM (40%) athletes was observed in the long distance group. A larger overuse injury incidence was observed in LM (4.1 inj/1000 h) and Norm (5.1 inj/1000 h) compared to early mature athletes (2.8 inj/1000 h). Apophysitis was the most common overuse injury, being significantly associated to maturation status (LM=4.1 inj/1000 h, Norm= 2.6 inj/1000 h, EM= 0.9 inj/1000 h; p<0.01), and long distance athletes the ones with a larger number of this kind of injuries (61%), and also with a larger training exposure (260 h per season). Conclusion: A predominance of late mature athletes was observed in long distance runners compared to all the other disciplines, and the risk of overuse injuries might increase when late mature athletes are exposed to large amounts of training during adolescence. Adapting training to maturation status and not to chronological age classical categories might reduce injury risk in adolescent track and field athletes.
HOP TEST AS A TOOL FOR THE ASSESSMENT AND PREVENTION OF INJURIES IN FOOTBALLERS DURING PRESEASON
Authors: García-Bol F , Posada-Franco V , Roldán-Valero A , Del Caño-Espinel R 
Published: June 2018

Hop Tests (unipodal horizontal jumps) have been recommended as one of the reliable assessment tests when allowing a return to competition for a sportsperson after an anterior cruciate ligament injury1,2,3,4. Currently, comparison is made of the results with the contralateral limb through the symmetry index, a method which might not provide sufficient security upon the return to competitive sport5. Hop tests can be used in preseason to gain reference values prior to a possible injury. The objective of this review is to analise the scientific literature such as the F-Marc6 (reference manual of FIFA) to confirm whether include said tests in preseason for football teams. A search was conducted in the Pubmed y Cochrane databases (17/04/17) with the search terms “Hop Test”, “Football”, “Soccer”, and “Preseason”. Articles in English and Spanish were both accepted. Articles excluded were those that did not make reference to the knee, to football, and those that did not conduct tests during preseason. From a total of 33 articles, 4 with these search criteria were included, 5 articles were added trough the bibliography of other studies, and the F-Marc manual was analised. 4 of the articles used the hop tests in preseason for some type of study, of which 3 were used as part of a prospective assessment for the season. On the other hand, the F-Marc does not consider Hop Tests as an assessment test. Hop tests were not found to be used in preseason as reference values prior to possible future injuries, data which could be beneficial for a safe return to sport. Harris J, Abrams G, Bach B, Williams D, Heidloff D, Bush-Joseph C, Verma N, Forsythe B, Cole B. Return to Sport After ACL Reconstruction. ORTHOPEDICS. 2014; 37: e103-e108. Barber-Westin SD, Noyes FR. Factors used to determine return to unrestricted sports activities after anterior cruciate ligament reconstruction. Arthroscopy. 2011 Dec;27(12):1697-705. Thomeé R, Kaplan Y, Kvist J, Myklebust G, Risberg MA, Theisen D, Tsepis E, Werner S, Wondrasch B, Witvrouw E. Muscle strength and hop performance criteria prior to return to sports after ACL reconstruction. Knee Surg Sports Traumatol Arthrosc. 2011 Nov;19(11):1798-805. Bolgla LA, Keskula DR. Reliability of lower extremity functional performance tests. J Orthop Sports Phys Ther. 1997 Sep;26(3):138-42. Wellsandt E, Failla MJ, Snyder-Mackler L. Limb Symmetry Indexes Can Overestimate Knee Function After Anterior Cruciate Ligament Injury. J Orthop Sports Phys Ther. 2017 Mar 29:1-18. F-MARC. Football Medicine Manual. 2nd Edition. Available from: http://f-marc.com . 2017.
SURGICAL TREATMENT OF CLAVICULAR FRACTURES IN SPORT
Authors: Gastaldi Orquin E , Gastaldi Llorens GM 
Published: June 2018

Clavicular fractures are common in sport practice, they are easily diagnosed and have a relative good forecast. Nevertheless there is no consensus among orthopedic surgeons regarding treatment for displaced midle-third clavicular fractures (Robinson’s classification 2B2) and lateral-third fractures. The tendency toward operative treatment is increasing due to the earlier sport recovery. Objectives: The aim of the paper is to present the results of treatment of 98 clavicular fractures in the Clinic Gastaldi of Traumatology during the period from 1997 to 2016, analyzing the radiologic and clinical results. Methods: The serie consists of 89 patients, 80 males and 9 females, average age 32.2 years. From them, 89 were agude fractures and 9 nonunion (after conservative treatment). According to the Thomsom classification there were 82 middle-third and 16 lateral-third. Motorbike sport trauma was the cause of 49 patients (55%), bike trauma in 18 (20%), 18 (20%) fractures occurred due to contact sports and 3 other causes. All patients were surgically treated. We used an antero-superior approach, open reduction and internal fixation with antero-superior plate osteosynthesis. In case of nonunion we decorticated the fracture callus, adding intramedullary reaming and graft bone. PRP (Platelet Rich-Plasma) was used in 8/9 patients. Postoperatively, the patients were placed in a sling. After that they began a rehabilitation program that consists of isometrics, pendular and active movements until 45° during 3 weeks. From 4th to 6th week, active movements until 90°. The patients began free movements after the 6th week. Results: Fracture healing mean was 10 weeks. Bikes and motorbikes were able to ride again between 10 to 21 days after surgery (once removed stitches). All patients retrieved full shoulder range of motion and returned to their previous activity level. Complications: we had no nonunion rates after surgical treatment, neither infections. 1 case of insufficient plate fixation and 4 re-fractures which required surgical treatment. Conclusion: We suggest surgical treatment for clavicular fractures in adult patients, contact sports with IIB and IIIB fractures, re-fractures and painful nonunion. Surgical treatment with open reduction and internal fixation (ORIF) of displaced middle-third clavicular fractures achieved shorter time to complete return to sport and earlier bone union.
SINCROBOX® as a method to improve shoulder’s function in mastectomized women
Authors: Espejo-Reina A , Becerra E , Candel R , Cerezo MV , Martin R , Meza H , Santiago C , Navarro A 
Published: June 2018

Objectives: To asses the effect of a sports discipline called SINCROBOX® (consisting in stationary biking coordinated with different arm exercises, namely grip strength, light weightlifts, elastic band stretching, etc) in the functional capacity of mastectomized women’s shoulder. Methods: A randomized blinded cohort study was carried out, with 2 groups of mastectomized women (due to breast cancer). The first one (28 patients) was subjected to SINCROBOX® training for three months, while the second one (22 patients) served as control group. Every patient was subjected to physical exam (range of motion measurement of the affected shoulder) and to functional shoulder tests (DASH, Constant, STT and Oxford) before beginning the training and after 3 months of exercise. A Student’s T test was performed for statistical analysis in each group. Results: Every variable assessed showed statistically significant advantages in the training group: range of motion increased more than 10° in all directions; SST (+20.9; p<0.001), DASH (-19.8; p<0.001), Constant (+15; p=0.004) and Oxford (+8.6; p< 0.001). There were no differences in the control group, before and after training. No complications were found in both groups. Conclusion: SINCROBOX® is a safe sports discipline that has the ability to improve mastectomized women’s shoulder’s functional capacity.
“SACCIA Safe Communication”: Five core competencies for safe and high-quality care
Authors: Hannawa Annegret F 
Published: June 2018

Background Communication has emerged as a critical component in delivering safe, high-quality care. The evidence is clear that health outcomes are enhanced when clinicians communicate well, and compromised when they interact poorly. It is important to understand the core aspects of interpersonal sense-making that hinder or foster favorable health outcomes. This study introduces an evidence-based “SACCIA Safe Communication” (Sufficiency, Accuracy, Clarity, Contextualization, Interpersonal Adaptation) framework to fill this gap. Method Sixty narratives of patient safety events were coded using qualitative content analysis guided by the “Hannawa SACCIA Safe Communication” framework. Results The analyses yielded 367 communication errors. Of these errors, 160 related to unsafe encoding, 92 to unsafe decoding, and 115 to unsafe transactional communication. Sufficiency errors were most frequent (124), followed by communication errors of contextualization (117), accuracy (84), interpersonal adaptation (26), and clarity (16). Conclusions The Hannawa SACCIA Safe Communication framework identifies interpersonal communication processes that commonly compromise the safety and quality of care. Narrative excerpts from the cases in this study exemplify what these processes look like in daily care encounters. The framework bridges across contexts and interpersonal settings. Furthermore, it explains various types of patient safety events (e.g. patient falls; unsafe handoffs or surgeries; diagnostic and medication errors). Therefore, it serves as a useful approach to describe and understand interpersonal communication as a critical factor in the provision of safe and high-quality care.