bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phrasale Konstruktionen als Basis narrativer Routinen
Authors: Lasch Alexander 
Published: April 2018

AbstractThe article focuses on the non-agent construction of the ASKRIPTION ofaussehen(er sieht mitgenommen aus, see basically Lasch 2016a) in the center of the considerations. On the basis of a corpuslinguistic evaluation of the KERN corpus at the DWDS it is shown that and why this construction belongs to the repertoire of linguistic patterns, which are especially established for descriptions in narrative texts.
Die Verdoppelung des Rassismus im Antirassismus
Authors: Jacob Günther 
Published: April 2018

Zusammenfassung„Kulturelle Vielfalt“, „interkulturelle Kompetenz“, „Community“ und „Respekt“ sind die Stichworte eines neuen identitären Antirassismus. Am Beispiel eines türkischen Community-Radios in Hamburg wird gezeigt, wie dieser kulturrelativistische Antirassismus die Migrationspolitik prägt und auch Komplizenschaften mit islamisierten Rechten produziert.
Was will Edward Saids Orientalismus?
Authors: Khawaja Irfan 
Published: April 2018

AbstractDer Essay legt dar, dass das Gründungsdokument der postkolonialen Studien aufgrund ernsthafter logischer Inkonsistenzen überhaupt gar keine stringente, diskutierbare These aufweist. Stattdessen dient Saids rhetorische Strategie in erster Linie dazu den Islam gegen Kritik zu immunisieren, dabei bedient er sich ausgerechnet der Mittel, die er dem Orientalismus zum Vorwurf macht.
Characterising Dynamic Instability in High Water-Cut Oil-Water Flows Using High-Resolution Microwave Sensor Signals
Authors: Liu Weixin , Jin Ningde , Han Yunfeng , Ma Jing 
Published: April 2018

Abstract
In the present study, multi-scale entropy algorithm was used to characterise the complex flow phenomena of turbulent droplets in high water-cut oil-water two-phase flow. First, we compared multi-scale weighted permutation entropy (MWPE), multi-scale approximate entropy (MAE), multi-scale sample entropy (MSE) and multi-scale complexity measure (MCM) for typical nonlinear systems. The results show that MWPE presents satisfied variability with scale and anti-noise ability. Accordingly, we conducted an experiment of vertical upward oil-water two-phase flow with high water-cut and collected the signals of a high-resolution microwave resonant sensor, based on which two indexes, the entropy rate and mean value of MWPE, were extracted. Besides, the effects of total flow rate and water-cut on these two indexes were analysed. Our researches show that MWPE is an effective method to uncover the dynamic instability of oil-water two-phase flow with high water-cut.
Surface Enhanced DNP Assisted Solid-State NMR of Functionalized SiO2 Coated Polycarbonate Membranes
Authors: Kumari Bharti , John Daniel , Hoffmann Paul , Spende Anne , Toimil-Molares Maria Eugenia , Trautmann Christina , Hess Christian , Ruff Philip , Schulze Marcus , Stark Robert , Buntkowsky Gerd , Andrieu-Brunsen Annette , Gutmann Torsten 
Published: April 2018

Abstract
Surface enhanced solid-state NMR by dynamic nuclear polarization (DNP SENS) enables the characterization of the inner-pore surface functionalization of porous etched ion-track membranes exhibiting low specific surface areas compared to typical SBA- or MCM-type mesoporous silica materials. The membranes were conformally coated with a 5 nm thin SiO2 layer by atomic layer deposition. This layer was subsequently modified by aminopropyl silane linkers that allow further functionalization via the terminal amine group. The results evidence that in principle DNP SENS is a capable tool to analyze more complex porous systems, e.g. bioinspired functional etched ion-track membranes down to the molecular level. These results are relevant also for single nanopore systems, for which a direct analysis of the channel surface functionalization is not feasible by classical characterization methods. The applicability of DNP SENS to complex porous systems requires the optimization of the sample preparation and measurement parameters.
Surface-Charge Dependent Orientation of Water at the Interface of a Gold Electrode: A Cluster Study
Authors: Fazio Gianluca , Seifert Gotthard , Rapacioli Mathias , Tarrat Nathalie , Joswig Jan-Ole 
Published: April 2018

Abstract
A gold/water interface has been investigated with the DFT-based self-consistent-charge density-functional tight-binding (SCC-DFTB) method using a cluster model. Born–Oppenheimer molecular-dynamics simulations for mono-, bi-, and trilayers of water on the surface of a Au55 cluster have been computed. We have demonstrated the applicability of this method to the study of the structural and dynamical properties of the gold/water-multilayer interface. The results of the simulations clearly show the charge-dependent orientation and the corresponding polarization of the water sphere around the gold cluster. However, it was also shown that this polarization is restricted almost only to the first solvation shell. This illustrates the rather short-range screening behavior of water. The present study builds the basis for further investigations of metal/electrolyte interfaces on a reliable atomistic level, avoiding the problems of spurious artifacts in models using periodic boundary conditions.
Fatigue Damage Characteristics Considering the Difference of Tensile-Compression Modulus for Asphalt Mixture
Authors: Lv Songtao , Wang Xiaoyang , Liu Chaochao , Wang Shuangshuang 
Published: April 2018

Abstract
In order to reveal the difference and correlation of tensile modulus, compressive modulus, and flexural modulus, the four-point bending fatigue test is used on two kinds of asphalt mixtures—rock asphalt modified asphalt mixture and styrene butadiene styrene block copolymer modified asphalt mixture, were conducted using closed-loop test system. The fatigue damage variable was defined by the modulus attenuation based on the theory of damage mechanics, and the modulus attenuation equation was deduced. Under the same conditions, the initial value and the critical value of the tensile modulus were less than those of the compressive modulus, but the critical damage value and the attenuation slope of the tensile modulus were larger than those of the compressive modulus. The attenuation models of the tensile and compressive modulus of the asphalt mixture during the bending fatigue test were established. Based on the fatigue test results, a new concept of design and analysis was developed, in which the corresponding modulus and its evolution law is chosen according to its actual stress state at each point of asphalt pavement. The results indicate that under the bending fatigue stress state, there exists great differences between the attenuation law of the modulus of tension and compression for asphalt mixture and that the attenuation rate of tensile modulus is greater than that of compressive. Therefore, the tensile zone results in greater damage; the pavement structure of the tensile zone is damaged, which should be given more attention.
Experimental Study on Impact Crushing of Granite Particles
Authors: Yang Jian-hong , Chen Qi , Zhou Jian-hua , Fang Huai-ying 
Published: April 2018

Abstract
To study the specific influences of production parameters and structural parameters on a vertical shaft impact crusher (VSI), a pneumatic impact crushing device was designed and used to study the influence of different impact velocities, impact angles, and initial particle sizes on the crushing effect for granite particles. The resulting grains size distribution (GSD) and the actual crushing ratio (ACR) were determined via mechanical sieving and image processing, where the experimental results showed that with increasing initial impact velocity the degree of fragmentation of the granite particles increased. However, when the impact velocity increased beyond a certain amount, the trend became more moderate. Further, there existed an optimum original particle size that allowed the degree of fragmentation of the particle to obtain a maximum value. Further, as the initial impact angle of the particles increased, the degree of fragmentation of granite particles exhibited a downward trend. Through the experimental study herein, it is found that the actual production parameters and structural parameters have significant effects on the impact crushing. According to these results, we can obtain valuable routines to guide the optimal design of the VSI.
Enhanced Oligodendrocyte Survival after Spinal Cord Injury in Bax-Deficient Mice and Mice with Delayed Wallerian Degeneration
Authors: Dong Hongxin , Fazzaro Alicia , Xiang Chuanxi , Korsmeyer Stanley J. , Jacquin Mark F. , McDonald John W. 
Published: April 2018

Mechanisms of oligodendrocyte death after spinal cord injury (SCI) were evaluated by T9 cord level hemisection in wild-type mice (C57BL/6J andBax+/+ mice), Wldsmice in which severed axons remain viable for 2 weeks, and mice deficient in the proapoptotic protein Bax (Bax-/-). In the lateral white-matter tracts, substantial oligodendrocyte death was evident in the ipsilateral white matter 3-7 mm rostral and caudal to the hemisection site 8 d after injury. Ultrastructural analysis and expression of anti-activated caspase-3 characterized the ongoing oligodendrocyte death at 8 d as primarily apoptotic. Oligodendrocytes were selectively preserved in Wldsmice compared with C57BL/6J mice at 8 d after injury, when severed axons remained viable as verified by antereograde labeling of the lateral vestibular spinal tract. However, 30 d after injury when the severed axons in Wldsanimals were already degenerated, the oligodendrocytes preserved at 8 d were lost, and numbers were then equivalent to control C57BL/6J mice.In contrast, oligodendrocyte death was prevented at both time points inBax-/- mice. When cultured oligodendrocytes were exposed to staurosporine or cyclosporin A, drugs known to stimulate apoptosis in oligodendrocytes, those fromBax-/- mice but not fromBax+/+ orBax+/- mice were resistant to the apoptotic death. In contrast, the three groups were equally vulnerable to excitotoxic necrosis death induced by kainate. On the basis of these data, we hypothesize that the Wallerian degeneration of white matter axons that follows SCI removes axonal support and induces apoptotic death in oligodendrocytes by triggering Bax expression.
Interleukin-1β Enhances NMDA Receptor-Mediated Intracellular Calcium Increase through Activation of the Src Family of Kinases
Authors: Viviani B. , Bartesaghi S. , Gardoni F. , Vezzani A. , Behrens M. M. , Bartfai T. , Binaglia M. , Corsini E. , Di Luca M. , Galli C. L. , Marinovich M. 
Published: April 2018

Interleukin (IL)-1β is a proinflammatory cytokine implicated in various pathophysiological conditions of the CNS involving NMDA receptor activation. Circumstantial evidence suggests that IL-1β and NMDA receptors can functionally interact. Using primary cultures of rat hippocampal neurons, we investigated whether IL-1β affects NMDA receptor function(s) by studying (1) NMDA receptor-induced [Ca2+]iincrease and (2) NMDA-mediated neurotoxicity. IL1β (0.01-0.1 ng/ml) dose-dependently enhances NMDA-induced [Ca2+]iincreases with a maximal effect of ∼45%. This effect occurred only when neurons were pretreated with IL-1β, whereas it was absent if IL-1β and NMDA were applied simultaneously, and it was abolished by IL-1 receptor antagonist (50 ng/ml). Facilitation of NMDA-induced [Ca2+]iincrease by IL-1β was prevented by both lavendustin (LAV) A (500 nm) and 4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine (PP2) (1 μm), suggesting an involvement of tyrosine kinases. Increased tyrosine phosphorylation of NMDA receptor subunits 2A and 2B and coimmunoprecipitation of activated Src tyrosine kinase with these subunits was observed after exposure of hippocampal neurons to 0.05 ng/ml IL-1β. Finally, 0.05 ng/ml IL-1β increased by ∼30% neuronal cell death induced by NMDA, and this effect was blocked by both lavendustin A and PP2.These data suggest that IL-1β increases NMDA receptor function through activation of tyrosine kinases and subsequent NR2A/B subunit phosphorylation. These effects may contribute to glutamate-mediated neurodegeneration.
A case with relapsed transient neonatal diabetes mellitus treated with sulfonylurea, ending chronic insulin requirement
Authors: Ando Akihiko , Nagasaka Shoichiro , Ishibashi Shun 
Published: April 2018

Summary
We report a case of a woman with diabetes mellitus caused by a genetic defect in ABCC8-coding sulfonylurea receptor 1 (SUR1), a subunit of the ATP-sensitive potassium (KATP) channel protein. She was diagnosed with diabetes at 7 days after birth. After intravenous insulin drip for 1 month, her hyperglycaemia remitted. At the age of 13 years, her diabetes relapsed, and after that she had been treated by intensive insulin therapy for 25 years with relatively poor glycaemic control. She was switched to oral sulfonylurea therapy and attained euglycaemia. In addition, her insulin secretory capacity was ameliorated gradually.

Learning points:

Genetic testing should be considered in any individuals or family with diabetes that occurred within the first year or so of life.

Sulfonylurea can achieve good glycaemic control in patients with KATP channel mutations by restoring endogenous insulin secretion, even if they were treated with insulin for decades.

Early screening and genetic testing are important to improve the prognosis of patients with neonatal diabetes mellitus arising from ABCC8 or KCNJ11 mutation.
One too many diabetes: the combination of hyperglycaemic hyperosmolar state and central diabetes insipidus
Authors: Burmazovic Snezana , Henzen Christoph , Brander Lukas , Cioccari Luca 
Published: April 2018

SummaryThe combination of hyperosmolar hyperglycaemic state and central diabetes insipidus is unusual and poses unique diagnostic and therapeutic challenges for clinicians. In a patient with diabetes mellitus presenting with polyuria and polydipsia, poor glycaemic control is usually the first aetiology that is considered, and achieving glycaemic control remains the first course of action. However, severe hypernatraemia, hyperglycaemia and discordance between urine-specific gravity and urine osmolality suggest concurrent symptomatic diabetes insipidus. We report a rare case of concurrent manifestation of hyperosmolar hyperglycaemic state and central diabetes insipidus in a patient with a history of craniopharyngioma.Learning points:In patients with diabetes mellitus presenting with polyuria and polydipsia, poor glycaemic control is usually the first aetiology to be considered.However, a history of craniopharyngioma, severe hypernatraemia, hyperglycaemia and discordance between urine-specific gravity and osmolality provide evidence of concurrent diabetes insipidus.Therefore, if a patient with diabetes mellitus presents with severe hypernatraemia, hyperglycaemia, a low or low normal urinary-specific gravity and worsening polyuria despite correction of hyperglycaemia, concurrent diabetes insipidus should be sought.
Predictive score for the development or progression of Graves’ orbitopathy in patients with newly diagnosed Graves’ hyperthyroidism
Authors: Wiersinga Wilmar , Žarković Miloš , Bartalena Luigi , Donati Simone , Perros Petros , Okosieme Onyebuchi , Morris Daniel , Fichter Nicole , Lareida Jurg , von Arx Georg , Daumerie Chantal , Burlacu Maria-Christina , Kahaly George , Pitz Susanne , Beleslin Biljana , Ćirić Jasmina , Ayvaz Goksun , Konuk Onur , Törüner Füsun Balos̜ , Salvi Mario , Covelli Danila , Curro Nicola , Hegedüs Laszlo , Brix Thomas , _ _ 
Published: April 2018

Objective
To construct a predictive score for the development or progression of Graves’ orbitopathy (GO) in Graves’ hyperthyroidism (GH).

Design
Prospective observational study in patients with newly diagnosed GH, treated with antithyroid drugs (ATD) for 18 months at ten participating centers from EUGOGO in 8 European countries.

Methods
348 patients were included with untreated GH but without obvious GO. Mixed effects logistic regression was used to determine the best predictors. A predictive score (called PREDIGO) was constructed.

Results
GO occurred in 15% (mild in 13% and moderate to severe in 2%), predominantly at 6–12 months after start of ATD. Independent baseline determinants for the development of GO were clinical activity score (assigned 5 points if score > 0), TSH-binding inhibitory immunoglobulins (2 points if TBII 2–10 U/L, 5 points if TBII > 10 U/L), duration of hyperthyroid symptoms (1 point if 1–4 months, 3 points if >4 months) and smoking (2 points if current smoker). Based on the odds ratio of each of these four determinants, a quantitative predictive score (called PREDIGO) was constructed ranging from 0 to 15 with higher scores denoting higher risk; positive and negative predictive values were 0.28 (95% CI 0.20–0.37) and 0.91 (95% CI 0.87–0.94) respectively.

Conclusions
In patients without GO at diagnosis, 15% will develop GO (13% mild, 2% moderate to severe) during subsequent treatment with ATD for 18 months. A predictive score called PREDIGO composed of four baseline determinants was better in predicting those patients who will not develop obvious GO than who will.
Wo steht der Selektivvertrieb?
Authors: Lubberger Andreas 
Published: April 2018

Zusammenfassung
Das Coty-Urteil des Europäischen Gerichtshofs vom Dezember 2017 wirft die Frage nach dem Spannungsverhältnis zwischen dem Selektivvertrieb und dem Kartellverbot neu auf. Für die rechtliche Ausgestaltung dieses Verhältnisses hat der heute vieldiskutierte Luxusbegriff keine Bedeutung. Maßgeblich sind die Begründungsmodelle für den Selektivvertrieb, die diesen entweder kartellrechtlich unter Kontrolle bringen oder ganz vom Kartellverbot befreien können. Auf der Grundlage dieser Modelle öffnet sich dann ein anderer Blick auf die beiden wichtigsten Fragen der Praxis nach (1) der Abgrenzung von selektiven und nicht-selektiven Absatzgebieten und (2) der Zulässigkeit von Beschränkungen des Onlinehandels.
Impulsivity traits and addiction-related behaviors in youth
Authors: Rømer Thomsen Kristine , Callesen Mette Buhl , Hesse Morten , Kvamme Timo Lehmann , Pedersen Michael Mulbjerg , Pedersen Mads Uffe , Voon Valerie 
Published: April 2018

Background and aims
Impulsivity is a risk factor for addictive behaviors. The UPPS-P impulsivity model has been associated with substance addiction and gambling disorder, but its role in other non-substance addiction-related behaviors is less understood. We sought to examine associations between UPPS-P impulsivity traits and indicators of multiple substance and non-substance addiction-related behaviors in youth with varying involvement in these behaviors.

Methods
Participants (N = 109, aged 16–26 years, 69% males) were selected from a national survey based on their level of externalizing problems to achieve a broad distribution of involvement in addiction-related behaviors. Participants completed the UPPS-P Questionnaire and standardized questionnaires assessing problematic use of substances (alcohol, cannabis, and other drugs) and non-substances (Internet gaming, pornography, and food). Regression analyses were used to assess associations between impulsivity traits and indicators of addiction-related behaviors.

Results
The UPPS-P model was positively associated with indicators of all addiction-related behaviors except problematic Internet gaming. In the fully adjusted models, sensation seeking and lack of perseverance were associated with problematic use of alcohol, urgency was associated with problematic use of cannabis, and lack of perseverance was associated with problematic use of other drugs than cannabis. Furthermore, urgency and lack of perseverance were associated with binge eating and lack of perseverance was associated with problematic use of pornography.

Discussion and conclusions
We emphasize the role of trait impulsivity across multiple addiction-related behaviors. Our findings in at-risk youth highlight urgency and lack of perseverance as potential predictors for the development of addictions and as potential preventative therapeutic targets.
Placing your faith on the betting floor: Religiosity predicts disordered gambling via gambling fallacies
Authors: Kim Hyoun S. , Shifrin Alexandra , Sztainert Travis , Wohl Michael J. A. 
Published: April 2018

Background and aims
We examined the potential role religious beliefs may play in disordered gambling. Specifically, we tested the idea that religiosity primes people to place their faith in good fortune or a higher power. In the context of gambling, however, this may lead to gambling fallacies (e.g., erroneous beliefs that one has control over a random outcome). People who are high in religiosity may be more at risk of developing gambling fallacies, as they may believe that a higher power can influence a game of chance. Thus, this research investigated the relationship between religiosity and gambling problems and whether gambling fallacies mediated this relationship.

Methods
In Study 1, we recruited an online sample from Amazon's Mechanical Turk to complete measures that assessed the central constructs (religiosity, disordered gambling, and gambling fallacies). In Study 2, we conducted a secondary analysis of a large data set of representative adults (N = 4,121) from a Canadian province, which contained measures that assessed the constructs of interest.

Results
In Study 1, religiosity significantly predicted gambling problem. Conversely, there was no direct relationship between religiosity and gambling in Study 2. Importantly, a significant indirect effect of religiosity on disordered gambling severity through gambling fallacies was found in both studies, thus establishing mediation. The results remained the same when controlling for age, gender, ethnicity, and socioeconomic status for both studies.

Discussion and conclusion
These findings suggest religiosity and its propensity to be associated with gambling fallacies, which should be considered in the progression (and possibly treatment) of gambling.