bluuebunny/crossref_metadata_2025_split huggingface dataset:
La stratigraphie de la parcelle de la Casa di Diana (I, iii, 3)
Authors: Mainet Grégory 
Published: November 2024

La Casa di Diana (I, iii, 3) figure parmi les édifices les plus emblématiques d’Ostie. Après la publication de la Topografia generale, en 1953, elle fut longtemps considérée comme une construction du milieu du IIe siècle apr. J.‑C. Voilà une vingtaine d’années, de nouvelles fouilles furent effectuées à l’intérieur de cet édifice et sa datation fut remontée de quelques décennies par le responsable des travaux, A. Marinucci. Cet article n’a pas la prétention de traiter l’ensemble des problèmes relatifs à cet édifice, qu’ils soient architecturaux ou urbanistiques : il ambitionne seulement de relire la stratigraphie de cette parcelle urbaine, en montrant plus spécifiquement que la Casa di Diana fut construite au tournant des IIe et IIIe siècles, à la place d’une riche demeure de l’aristocratie municipale.
La pratica orale e scritta della protestatio de iustitia nel Quattrocento fiorentino: il caso di Pandolfo di messer Giannozzo Pandolfini (1424-1465)
Authors: Bassani Claudia 
Published: November 2024

Il contributo propone l’edizione della protestatio de iustitia scritta e pronunciata nel maggio 1465 dall’ambasciatore e umanista fiorentino Pandolfo Pandolfini (1424-1465). L’orazione, ricordata con ampi elogi da Vespasiano da Bisticci all’interno delle Vite, è stata a lungo considerata perduta ed è quindi rimasta inedita. L’analisi del protesto, rinvenuto all’interno di due manoscritti miscellanei molto diversi tra loro, offre lo spunto per riflettere sulle finalità della trascrizione di questo particolare tipo di oralità politica, strettamente connesso con le pratiche del cerimoniale civile della Firenze comunale. Un secondo protesto, inoltre, rimaneggiamento anonimo del discorso pandolfiniano, ritrovato all’interno di un codice dell’antica biblioteca Pandolfini, contribuisce a confermare quanto osservato circa il basso livello di autorialità di questi discorsi politici.
L’inventaire du patrimoine à la lumière des sources orales
Authors: Pierrot Nicolas 
Published: November 2024

Depuis 2018, les institutions en charge de l’inventaire et de la valorisation du patrimoine redécouvrent l’histoire presque millénaire des Grands Moulins de Corbeil. D’importants moyens ont été déployés, associant recherche, photographie, exposition, film documentaire et outil numérique. Pourquoi tant d’égard ? Il convenait, dans l’urgence, d’accompagner la double mutation d’un site exceptionnel : à l’ouest, un « moulin 4.0 » s’élevait à l’ombre de la Tour élévatrice des grains, protégée au titre des monuments historiques ; à l’Est, une opération d’urbanisme à fort enjeu économique, social et mémoriel, promettait de respecter un patrimoine auquel la population demeurait fortement attachée. Cinq ans de recherche-action ont permis de développer cette pluridisciplinarité que Maurice Daumas prônait sans relâche dans l’exercice de l’histoire des techniques et de l’archéologie industrielle. Et de réduire peut-être la division artificielle entre l’inventaire du patrimoine matériel et la mobilisation de la mémoire. Cet article retrace cette expérience, en présentant successivement les jeux d’acteurs, les contraintes et opportunités d’une enquête en entreprise et la méthodologie de l’histoire orale appliquée au patrimoine industriel. Il explore ensuite les limites et surtout les bénéfices scientifiques de la démarche, en histoire de l’architecture, des techniques et du travail, offrant de stimulants arguments à la protection de l’existant. Au cœur de la réflexion, on retrouve la relation de l’homme à l’immensité de l’usine, son rôle dans ce monument où la présence de la machine l’emporte sur celle de l’humain. Le meunier comme médecin du gigantesque organisme, auquel il prodigue des soins incessants mais dont il redoute les dangers ; le meunier et ses équipes tendus vers leurs objectifs et bercés par la mémoire des lieux, toujours stimulés par la monumentalité et la beauté de l’architecture.
Effectiveness of exercise-based rehabilitation on functionality and quality of life in breast cancer survivors undergoing chemo-radiotherapy: A systematic review and meta-analysis
Authors: Martín Pérez Sebastián Eustaquio , Martín Pérez Isidro Miguel , Martín Álvarez Nayara , Méndez Fernández Nauzet , Almagro Luis Rocío Montserrat 
Published: November 2024

Abstract:
Breast cancer survivors often face physical and psychological complications post-chemoradiotherapy, including fatigue, muscle weakness, pain, and reduced quality of life (QoL). This systematic review and meta-analysis, conducted according to PRISMA guidelines, aimed to evaluate the effectiveness of exercise-based rehabilitation in improving functionality and QoL in breast cancer survivors. Databases such as MEDLINE, PEDro, Cochrane Library, and CINAHL Complete were searched for studies published between January 2014 and August 2024. The methodological quality was assessed using the PEDro scale, and bias was evaluated with the Cochrane RoB 2.0 tool. Evidence certainty was determined via the GRADE framework. The intervention significantly reduced fatigue (standardized mean difference [SMD] = −0.50, 95% confidence interval [CI]: −0.60 to −0.40, P < 0.00001). However, no significant effect was observed for aerobic capacity (VO2 max) (SMD = −0.06, 95% CI: −0.58–0.46; P = 0.83), though long-term interventions showed slight improvements. Muscle strength significantly increased (SMD = 1.02, 95% CI: 0.17–1.87, P = 0.02), with gains in both upper and lower limbs. Pain outcomes were mixed, with long-term interventions showing a small but significant reduction (SMD = −0.35, 95% CI: −0.69 to −0.02, P = 0.05). QoL significantly improved (SMD = 0.94, 95% CI: 0.42–1.46, P = 0.0004), with long-term interventions showing greater effects (SMD = 1.25, 95% CI: 0.34–2.15, P = 0.007). In conclusion, exercise-based rehabilitation reduces fatigue, improves muscle strength, and enhances QoL. Standardized protocols are needed to generalize benefits across broader populations. that these benefits can be generalized across broader populations. Further research should focus on developing tailored and standardized exercise regimens to maximize patient outcomes.
Escharotic Therapy vs. Primary Facial Closure for Omphalocele: An Early Outcome Analysis
Authors: Gurjar Bhairu L. , Gupta Rahul 
Published: November 2024

ABSTRACT

Context:
Omphalocele is a congenital midline periumbilical abdominal wall defect with the herniated visceral organs covered by a membrane. The morbidity and mortality of neonates with omphalocele in our geographical area are under-evaluated.

Aims:
The aim of the study was to compare the early outcomes of omphalocele using two different management modalities, that is, either escharotic therapy or primary facial closure from a high-volume institute in India.

Settings and Design:
This prospective observational study was undertaken over a one-year duration extending from January to December 2021 at our pediatric tertiary care teaching institute.

Subjects and Methods:
The study included all patients with omphalocele admitted to the neonatal intensive care unit. The decision for management of the neonates with either escharotic therapy or primary facial closure was performed as per the discretion of the unit head.

Results:
There were 16 neonates with omphalocele; 10 (62.5%) males and six (37.5%) females. The mean birth weight was 2575 ± 839 g (range = 1700–5000 g). Associated major malformations/syndromes were observed in five (31.25%) patients. Group A (escharotic therapy) had nine patients with major omphalocele and two patients with minor omphalocele. Group B (primary facial closure of the defect) constituted four minor omphaloceles and one omphalocele major with a ruptured sac. Out of 11 patients in group A, nine survived (favorable outcomes); the cause of death in two patients was associated with cyanotic heart disease and cloacal exstrophy. Out of the five patients in group B, two survived (favorable outcomes); the cause of death in two patients was postoperative sepsis due to ruptured sac and associated OEIS syndrome. One patient had multi-organ dysfunction syndrome as a consequence of abdominal compartment syndrome.

Conclusions:
The survival percentage of neonates with escharotic therapy (81.82%) was better than primary facial closure (40%). The creation of ventral hernia is a better modality of management in neonates with omphalocele, especially in a resource-limited center.
Value of serum pepsinogen ratio screening for early gastric cancer and precancerous lesions in Youcheng area
Authors: Han Xue , Yu Wei 
Published: November 2024

BACKGROUND
The 5-year survival rate of patients with advanced gastric cancer remains extremely low (< 15%), whereas the 5-year survival rate of patients with early gastric cancer (EGC) is > 90%. Consequently, strengthening the screening of patients with EGC and precancerous lesions (PCLs) is essential.
AIM
To identify the value of serum pepsinogen ratio (PGR) screening for EGC and PCLs in the Shengli Oilfield Central Hospital.
METHODS
We first selected 385 patients with gastric lesions in the Youcheng area, determining benign lesions, PCLs, and EGC in 135, 123, and 127 cases, respectively, based on endoscopy and case diagnosis. The positive rates of pepsinogen I, pepsinogen II and Helicobacter pylori (H. pylori ) in the three groups were detected, and the PGR was calculated. Subsequently, we plotted receiver operating characteristic curves to analyze the screening value of PGR and H. pylori -positive rates for PCLs and EGC.
RESULTS
PGR expression demonstrated a decreasing trend in patients with benign lesions, PCLs, and EGC successively according to the detection results, whereas the H. pylori -positive rate was notably increased in patients with PCLs and EGC compared to those with benign lesions. The area under the curves (AUCs) of PGR, H. pylori , and their combination in differentiating patients with benign lesions from those with PCLs were 0.611, 0.582, and 0.689, respectively; PGR, H. pylori , and their combination had an AUC of 0.618, 0.502, and 0.618 in distinguishing PCL patients from EGC patients, respectively; the AUCs of PGR, H. pylori , and their combination in discriminating patients with benign lesions from those with EGC were 0.708, 0.581, and 0.750, respectively.
CONCLUSION
PGR has great screening potential for patients with EGC and PCLs in the Youcheng area, and the screening efficiency is further improved by combining the H. pylori -positive rate.
Prognostic value of combined systemic inflammation response index and prognostic nutritional index in colorectal cancer patients
Authors: Li Ke-Jin , Zhang Zi-Yi , Sulayman Subinur , Shu Yin , Wang Kuan , Ababaike Saibihutula , Zeng Xiang-Yue , Zhao Ze-Liang 
Published: November 2024

BACKGROUND
The prognosis of colorectal cancer (CRC) patients is notably influenced by both inflammation and nutritional status. The prognostic nutritional index (PNI) and systemic inflammatory response index (SIRI) have been reported in prognostic studies of various tumors. However, the efficacy of the combination of the two in predicting the prognosis of CRC patients has not been studied.
AIM
To evaluate the effectiveness of PNI and SIRI in predicting the prognosis of patients with CRC.
METHODS
We retrospectively gathered data from 470 CRC patients who underwent feasible radical surgery at Xinjiang Cancer Hospital. The optimal cut-off values for SIRI and PNI, along with their predictive power for survival, were determined through area under the receiver operating characteristic curve using time-dependent receiver operating characteristic analysis. The Kaplan-Meier method and log-rank test were applied to assess prognostic impact, and a multifactorial Cox proportional hazards model was employed for analysis. Additionally, a new model, PSIRI, was developed and assessed for its survival prediction capability.
RESULTS
The optimal cutoff values for PNI and SIRI were determined to be 47.80 and 1.38, respectively. Based on these values, patients were categorized into high PNI and low PNI groups, as well as high SIRI and low SIRI groups. Significant differences in age, T stage, neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), and platelet-to-lymphocyte ratio (PLR) subgroups were observed between the PNI groups in the baseline profile. In the SIRI group, notable differences were found in gender, T stage, nerve invasion, intravascular tumor emboli, NLR, MLR, and PLR subgroups. Both low PNI and high SIRI were identified as independent risk factors for poor prognosis in CRC patients. When combined into the PSIRI model, it was shown that patients with a PSIRI ≤ 1 had a higher risk of death compared to those with a PSIRI of 2.
CONCLUSION
We assessed the impact of PNI and SIRI on the prognostic survival of CRC patients and developed a new model, PSIRI. This model demonstrated superior predictive accuracy, with a concordance index of 0.767.
Diagnostic value of digital continuous bowel sounds in critically ill patients with acute gastrointestinal injury: A prospective observational study
Authors: Sun Yuan-Hui , Song Yun-Yun , Sha Sha , Sun Qi , Huang Deng-Chao , Gao Lan , Li Hao , Shi Qin-Dong 
Published: November 2024

BACKGROUND
Acute gastrointestinal injury (AGI) is common in intensive care unit (ICU) and worsens the prognosis of critically ill patients. The four-point grading system proposed by the European Society of Intensive Care Medicine is subjective and lacks specificity. Therefore, a more objective method is required to evaluate and determine the grade of gastrointestinal dysfunction in this patient population. Digital continuous monitoring of bowel sounds and some biomarkers can change in gastrointestinal injuries. We aimed to develop a model of AGI using continuous monitoring of bowel sounds and biomarkers.
AIM
To develop a model to discriminate AGI by monitoring bowel sounds and biomarker indicators.
METHODS
We conducted a prospective observational study with 75 patients in an ICU of a tertiary-care hospital to create a diagnostic model for AGI. We recorded their bowel sounds, assessed AGI grading, collected clinical data, and measured biomarkers. We evaluated the model using misjudgment probability and leave-one-out cross-validation.
RESULTS
Mean bowel sound rate and citrulline level are independent risk factors for AGI. Gastrin was identified as a risk factor for the severity of AGI. Other factors that correlated with AGI include mean bowel sound rate, amplitude, interval time, Sequential Organ Failure Assessment score, Acute Physiology and Chronic Health Evaluation II score, platelet count, total protein level, blood gas potential of hydrogen (pH), and bicarbonate (HCO3-) level. Two discriminant models were constructed with a misclassification probability of < 0.1. Leave-one-out cross-validation correctly classified 69.8% of the cases.
CONCLUSION
Our AGI diagnostic model represents a potentially effective approach for clinical AGI grading and holds promise as an objective diagnostic standard for AGI.
Laparoscopic cholecystectomy with communicating accessory hepatic duct injury and management: A case report
Authors: Zhao Peng-Ju , Ma Yan , Yang Ji-Wu 
Published: November 2024

BACKGROUND
Laparoscopic cholecystectomy is considered the gold standard for the treatment of patients with gallstones. However, bile duct injury is one of the most serious complications of this surgery, with an incidence rate of 0.3%-0.7%. Variations in anatomical structures are one of the main reasons for such injuries.
CASE SUMMARY
We report a 26-year-old male patient who presented with repeated upper abdominal pain for 1 year. Ultrasound examination and blood tests indicated gallstones accompanied by chronic cholecystitis. The patient underwent laparoscopic cholecystectomy. During the surgery, a communicating bile duct connecting the gallbladder neck and the right hepatic duct was discovered and injured. Meticulous dissection identified it as a communicating accessory hepatic duct, which was then definitively ligated. Postoperatively, the patient recovered well, magnetic resonance imaging and magnetic resonance cholangiopancreatography showed no intrahepatic or extrahepatic bile duct strictures. The pathology report showed chronic cholecystitis with gallstones.
CONCLUSION
Carefully manage communicating accessory bile ducts in cholecystectomy using cholangiography or meticulous separation, followed by ligation is effective.
Evaluation of Shampakadi Basti and Kshar Basti along with Pristha Basti in Trik Grah (Ankylosing Spondylitis)
Authors: Mohit Bagwari  , Piyush Gupta  , Praphull Goyal  , Ketan Mahajan  
Published: November 2024

Basti is considered the most effective treatment for Vata, as well as for Pitta, Kapha, and Rakta (blood) in Samsarga, and Sannipata Doshaas. Within the 'Nanatmaja vyadhi' of Vata, Charaka sutra 20/10 mentions a total of eighty types of Vata Rogas, known as Ashiti Roga. Trik-Asthi is sacrum bone. Sacroiliitis is often the earliest manifestation of ankylosing spondylitis. Ankylosing spondylitis is a complex, and systemic inflammatory rheumatic disease mainly affecting the axial skeleton, with the potential to cause severe debilitation. Fibrosis and ossification of tendon, ligament and capsule insertion at the area of sacroiliac and intervertebral discs are the main characteristics of ankylosing spondylitis. Eighty types of Nanatmaja Vata Vikara caused by Vata. Trik Grah one of the Vata Nanatamaja Vyadhi. Vata-Vyadhies can be considered as a group of such diseases, which Modern Science has given different names. Methods: This clinical study was done to “Evaluation of Shampakadi Basti and Kshar Basti along with Pristha Basti in Trik Grah (ankylosing spondylitis)”. Basti Karma is known to be the best for Vata disorders thus for this research, open labelled clinical study was done wherein 50 patients were taken in random manner having symptoms of Trik Grah and were divided into two groups, Group A received Shampakadi Basti along with Pristha Basti and Group B received Kshar Basti along with Pristha Basti daily for 8 days. Results: Evaluation and the result of both the group exhibited that the improvement provided by group B was better in both sign & symptoms like Sandhi Shool (pain), Sandhi Jadyata (stiffness), Angamarda (fatigue), quality of sleep in comparison to group A. Conclusion: As Vata vitiation is a cause Trik Grah, no other treatment modality act as good as Basti. As Ama involvement was there, which was obstructing or vitiating the Samanya Vata action, thus Shampakadi Basti and Kshar Basti along with Pristha Basti showed encouraging results in this disease.
Investing in Tomorrow: How Indonesian Firms Allocate Free Cash Flow for Sustainability Development Strategy
Authors: Junias Donny Teguh Santoso , Suharto Raden Setyo Budi 
Published: November 2024

Objective: This study is to investigates and prove the role of management ownership in the use of free cash flow to fund the social environment financing (Sustainability Accounting), and as the company's sustainability development strategic objectives.

Theoretical Framework: Sustainability accounting has long been disputed in developing nations and certain industrial settings, and it remains among its most crucial issues in the business sector. Sustainability accounting is also used to assess or evaluate firm performance, provide accounting information, and make economic assessments relating to investment and managerial decisions, total asset expenditures, capital costs, or other strategic decisions for companies related to social responsibility, meaning that companies do not only prioritize profit but also deserves attention to the social-environmental factors of the communities in which they operate. This policy is aimed at preventing conflicts of interest between internal and external stakeholders of the organization, and can protect the company's reputation

Method: The method utilizes pure-moderated regression model and using the purposive sampling method, data pooling is based on the company's ISX-listed financial statements on 2016-2020 period, and has an Environmental Performance Management index on Green-Gold PROPER.

Results and Discussion: The results of the t-test showed a significance value of pure-moderating effect of managerial ownership to intervene free cash flow in sustainability accounting. This means that in order to overcome the socio-ecological accounting crisis, in addition to profit orientation, companies make sustainability responsibility one of the most important factors in their business operations.

Research Implications: Management ownership plays a positive role and has a significant impact on sustainability accounting. Even if they hold a relatively small number of shares, they can influence the use of free cash flow for the benefit of sustainability accounting. Free cash flow is not only used to return profits to shareholders, but also to benefit social and environmental programs when companies make strategic decisions. This result in line with the legitimacy theory, which states that the existence and sustainability of corporate operations is confirmed by their conformity with the interests and expectations of the community.

Originality/Value: This study contributes to clarifying why a company's sustainability can be verified through sustainable accounting. This research suggests that one essential aspect in resolving the socio-environmental accounting crisis was sustainability responsibility.
Региональная государственная программа как правовой инструмент развития кадровых ресурсов в здравоохранении (на примере Саратовской области)
Authors: И.Н. Осипова , О.П. Салтыкова , В.В. Масляков 
Published: November 2024

На основе результатов реализации государственной политики в сфере здравоохранения Саратовской области авторы статьи анализируют роль государственной программы как правового инструмента развития кадровых ресурсов в здравоохранении. Под эффективностью государственной программы как правового инструмента авторы понимают соотношение между целью государственной программы и результатом, который должен выражаться в социально-значимом эффекте.
Based on the results of the implementation of the state policy in the field of healthcare in the Saratov region, the authors of the article analyze the role of the state program as a legal tool for the development of human resources in healthcare. By the effectiveness of the state program as a legal instrument, the authors understand the relationship between the purpose of the state program and the result, which should be expressed in a socially significant effect.
Awareness, Knowledge and Pattern of Substance Use among Undergraduate Students in a Tertiary Institution in Ekiti State, Nigeria
Authors: Oluremi Olayinka Solomon  , Eyitope Oluseyi Amu1  , Ajayi Paul Oladapo , Olusoji Abidemi Solomon , Moyinoluwa Oyindamola Adeosun  
Published: November 2024

Purpose: The rate at which the young people are getting involved in drug abuse is alarming, good knowledge of these substances should be able to affect the risky behaviour of the youths. This study examined the awareness, knowledge and pattern of substance use among undergraduates in a tertiary institution in Ekiti-State.
Materials and Methods: A cross-sectional study among 460 undergraduates using multi-stage sampling technique. Pre-tested, semi-structured questionnaire was administered, and data analysed using SPSS version 26. Descriptive analysis was done with figures, tables and percentages and association between dependent and independent variable with binary logistic regression.
Findings: Mean age of the participants was 21.82±2.6 years. Almost all were aware of substance use 445 (96.5%) and 241 (52.8%) had good knowledge. Younger age and being a male were associated with good knowledge of substance use with p value < 0.05.
Unique Contribution to Theory, Practice and Policy: Awareness was good among participants while knowledge was average and being young and male gender were predictors. It is recommended that comprehensive education should be given starting from younger age group with more parental monitoring on the male child.