bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flow-induced, inflammation-mediated arterial wall remodeling in the formation and progression of intracranial aneurysms
Authors: Frösen Juhana , Cebral Juan , Robertson Anne M. , Aoki Tomohiro 
Published: July 2019

OBJECTIVEUnruptured intracranial aneurysms (UIAs) are relatively common lesions that may cause devastating intracranial hemorrhage, thus producing considerable suffering and anxiety in those affected by the disease or an increased likelihood of developing it. Advances in the knowledge of the pathobiology behind intracranial aneurysm (IA) formation, progression, and rupture have led to preclinical testing of drug therapies that would prevent IA formation or progression. In parallel, novel biologically based diagnostic tools to estimate rupture risk are approaching clinical use. Arterial wall remodeling, triggered by flow and intramural stresses and mediated by inflammation, is relevant to both.METHODSThis review discusses the basis of flow-driven vessel remodeling and translates that knowledge to the observations made on the mechanisms of IA initiation and progression on studies using animal models of induced IA formation, study of human IA tissue samples, and study of patient-derived computational fluid dynamics models.RESULTSBlood flow conditions leading to high wall shear stress (WSS) activate proinflammatory signaling in endothelial cells that recruits macrophages to the site exposed to high WSS, especially through macrophage chemoattractant protein 1 (MCP1). This macrophage infiltration leads to protease expression, which disrupts the internal elastic lamina and collagen matrix, leading to focal outward bulging of the wall and IA initiation. For the IA to grow, collagen remodeling and smooth muscle cell (SMC) proliferation are essential, because the fact that collagen does not distend much prevents the passive dilation of a focal weakness to a sizable IA. Chronic macrophage infiltration of the IA wall promotes this SMC-mediated growth and is a potential target for drug therapy. Once the IA wall grows, it is subjected to changes in wall tension and flow conditions as a result of the change in geometry and has to remodel accordingly to avoid rupture. Flow affects this remodeling process.CONCLUSIONSFlow triggers an inflammatory reaction that predisposes the arterial wall to IA initiation and growth and affects the associated remodeling of the UIA wall. This chronic inflammation is a putative target for drug therapy that would stabilize UIAs or prevent UIA formation. Moreover, once this coupling between IA wall remodeling and flow is understood, data from patient-specific flow models can be gathered as part of the diagnostic workup and utilized to improve risk assessment for UIA initiation, progression, and eventual rupture.
The Early History of Water Wars in Chile: Rivers, Ecological Disaster and Multinational Mining Companies
Authors: Klubock Thomas Miller 
Published: July 2019

Abstract
This article examines an early water war in Chile between local agriculturalists and the North American-owned El Teniente copper mine. It recovers a hitherto unknown history of ecological degradation caused by industrial copper mining during the twentieth century in Chile. It argues that contemporary water wars in Chile, usually viewed as a product of the privatisation of water rights in 1981 and the expansion of foreign investment in the mining sector during the 1990s, combined with the impact of global climate change, have roots in the appropriation of water in Andean rivers by North American companies at the beginning of the twentieth century. The article's thesis is that the Chilean state subsidised the mining industry by granting water rights and turning a blind eye to mining companies' contamination of rivers relied on by agriculturalists for irrigation. Finally, the article traces conservationist responses to the ecological crises produced by contamination of water and soil by the El Teniente mine, which was owned by the Kennecott Copper Company. It demonstrates that conservation of water resources was employed by estate owners as a means of asserting private property rights against the interests of mining companies.
Mateship with Nature: Nationalism and Conservation in the Writings of Alec Chisholm
Authors: McGregor Russell 
Published: July 2019

Abstract
Alec Chisholm (1890-1977) inspired generations of Australians to see nature anew. A prolific writer of popular works of natural history, he promoted a conservationist ethos. He also promoted an Australian nationalism that cherished the landscapes, flora and fauna of that country. This article explores the entwining of Chisholm's love of nature with his commitment to Australian nationalism. In doing so, it teases out some of the complexities and ambiguities that threaded through the evolution of a conservationist ethos in Australia in the middle decades of the twentieth century.
Frequency response signature analysis for winding mechanical fault detection of power transformer using sensitivity method
Authors: Zhang Haijun , Zhang Hua , Ma Qiang , Han Haifeng , Wang Shuhong 
Published: July 2019

Frequency Response Analysis (FRA) is an effective diagnosis approach to detect the winding mechanical faults in power transformer. For understanding the FRA signatures of transformer windings quantitatively, this paper uses the sensitivity method to study the characteristics of frequency response function (FRF) in equivalent circuit of transformer windings. The sensitivity expressions of FRF can be determined by adjoint network method and Tellegen theorem, which reflects the influence of electric parameter changes on FRA signature under winding faults and within a wide-frequency band (10 Hz to 2 MHz). To verify the sensitivity calculation, a two-winding transformer model with seven discs was established and taken as an example. The results indicate that FRF sensitivity data can provide the valuable insights about how the frequency responses are affected quantitatively with respect to the electric parameter changes or different winding faults. The method and sensitivity analysis discussed in this paper may be useful for diagnosing and predicting different mechanical deformation faults of transformer windings.
Perinatal grief following neonatal comfort care for lethal fetal condition
Authors: Depoers-Béal C. , Le Baccon F.A. , Le Bouar G. , Proisy M. , Arnaud A. , Legendre G. , Dayan J. , Bétrémieux P. , Le Lous M. 
Published: July 2019

BACKGROUND: The objective of the study was to assess perinatal grief experienced after continuing pregnancy and comfort care in women diagnosed with lethal fetal condition compared with termination of pregnancy for fetal anomaly (TOPFA). METHODS: This was a retrospective observational study which included women who chose to continue their pregnancy after the diagnosis of lethal fetal condition with comfort care support at birth at the Prenatal Diagnosis Center of Rennes Hospital from January 2007 to January 2017. Women were matched with controls who underwent TOPFA for the same type of fetal anomaly, gestational age at diagnosis and year. Women were evaluated by a questionnaire including the Perinatal Grief Scale. RESULTS: There were 28 patients in the continuing pregnancy group matched with 56 patients in the TOPFA group. Interval between fetal loss and completion of questionnaire was 6±3 years. Perinatal grief score was similar at 61±22 vs 58±18 ( p = 0.729) in the continuing pregnancy and TOPFA groups, respectively. Women in the TOPFA group expressed more guilt. The cesarean-section rate in the continuing pregnancy group was 25%. CONCLUSION: Perinatal grief experienced by women opting for continuing pregnancy and comfort care after diagnosis of a potentially lethal fetal anomaly is not more severe than for those choosing TOPFA.
FINANCIAL STABILITY OF A BANK - FACTOR OF STABILITY OF BANKING SYSTEM
Authors: Ramskyi Andrii , Budnichenko Inna 
Published: July 2019

The article is devoted to the analysis of the financial stability of Ukrainian banks at the present stage of development and the identification of the main factors of influence that are associated with it. The main tendencies of development of the banking system of Ukraine are considered. The present state of the banking system of Ukraine is determined. Financial stability plays a significant role in planning the activities of commercial banks. In general, its indicators reflect the level of riskiness of the functioning of the entity of the banking system. Managing financial sustainability has a significant impact on the functioning of banks. That is why it is necessary to create special control departments in banking institutions. The research of financial stability of banks is based on financial sustainability indicators developed and used by the IMF and the World Bank as the basis for the "Integrated Financial Sector Development Program until 2020". The necessity of applying different methods for evaluating the financial stability of commercial banks has been established in order to identify a wider range of problems related to the efficiency of the functioning of the banking system. The description of two main groups of factors, under the influence of which the financial stability of banks undergoes changes, is presented. It was revealed that external factors have a more significant impact on the financial stability of a bank. In particular, the factors of mega environment have become more important when banks enter the international financial space. Internal factors lie mostly in the management plane, and it is just the inefficient management of the bank that leads to the disruption of its stable financial condition. Specific features of management of financial stability and methods of its evaluation are considered. The analysis of economic standards of the banking system of Ukraine is carried out. The measures are proposed to minimize the risks and maintain the stability of banking institutions at the required level for normal functioning in modern conditions. It has been proved that providing, supporting, analyzing and evaluating the financial stability of commercial banks is a driving force in the development of the banking system, and hence the entire Ukrainian economy.
ІННОВАЦІЙНЕ УПРАВЛІННЯ ОСВІТНЬОЮ ДІЯЛЬНІСТЮ ВИЩИХ НАВЧАЛЬНИХ ЗАКЛАДІВ
Authors: Shaporenko Olga , Parshchenko Lyudmila 
Published: July 2019

Перехід від індустріального до інформаційного суспільства, так званого «суспільства знань», провокує формування нового типу економіки, заснованої на знаннях, де процеси створення та розподілення знань стають ключовими. В наш час знання вже є капіталом і головним ресурсом держави. Зміна соціальних орієнтацій провокує спрямування акценту на кожну окрему особистість, як основну соціальну цінність. Вибір інноваційного типу розвитку, створення та впровадження наукових технологій, постійно зростаюча роль інформації та знань у соціально-економічному розвитку держави призводять до підвищення попиту на висококваліфікованих фахівців. Крім того, формування інноваційної моделі розвитку суспільства розширює коло функціональних особливостей системи вищої освіти в напрямку поєднання функції передачі накопиченого суспільного досвіду, знань та навичок зі сприянням у розробці нових наукових ідей, технічних рішень і технологічних процесів та підготовкою фахівців нового рівня, які відзначаються розвинутими аналітичними та професійними здібностями. Вища школа покликана стати центром формування інноваційного середовища, що забезпечить спрямованість професійної підготовки на формування готовності майбутніх фахівців до інноваційної діяльності. Враховуючи вище зазначене, у статті проаналізовано правове поле, у якому функціонує система освіти нашої держави, виокремлено класично-управлінські моделі, що можуть бути реалізовані у процесі вирішення нагальних управлінських проблем сьогодення, а також міжнародний досвід, пов’язаний із питанням дослідження інноваційної складової менеджменту освітою. Підкреслено важливість застосування принципу інноваційності для вдосконалення професійної компетентності керівника ВНЗ. У статті розглянуто проблему формування й удосконалення професійної компетентності управлінських кадрів завдяки моделюванню їхньої діяльності. Запропоновано діяльність вищого навчального закладу розглядати як єдину цільову програму. Визначено основні напрямки інноваційного управління, цілі внутрішніх підсистем діяльності вищих навчальних закладів, розкрито їх структурні складові та функції управління освітньою діяльністю.
Theoretical schools on employment and workforce
Authors: Béresné Mártha Bernadett 
Published: July 2019

In the civil economics, like in the case of any other socialeconomic issues, there are two coexistent theories concerning employment. On one hand we have the classical-neo-classicalschool based on Adam Smith’s works. On the other hand we have the teachings based on John Maynard Keynes’ views. All the later hypotheses are based on these two trends.Monetarism, which was invented at the beginning of the 20th century, mixes certain elements of both basic theories. Those who represent monetarism agree on rejecting the economy policymeans which affect the processes of the workforce market, while they consider these above mentioned means applicable to regulate certain processes. By the end of the 1970s the neo-classical macro-economics had developed, which completely refuses these approaches. A decade later the neo-Keynesian macro-economics developed. Its hypotheses regarding especially employment and unemployment lead to some of the employment issues of globalism, which is one of the most influential phenomena of present time.
Evaluation of supporting in Derecske-Létavétes micro-regional area
Authors: Suta Éva 
Published: July 2019

The occasion that joining to the European Union general several new opportunities which are supporting development, changes and increasing disadvantages. We tried to capitalizing these resources less or major rate in national and international level too. These opportunities are projects, tenders whose longterm effects are measured difficulty, it is a hard task. In spite of this fact I feel it has got basement importance to determine project activity forming future developments and ways. In my study I deal with Derecske-Létavértes Sub-region. My aims to survey economic background of this sub-region, seeking contexts between economical factors, influential agents and project activity or results. In a settlement level it is essential what kind of supporting forms are available for entrepreneurs, civil organization, economic development and local government, what are the founds could be realized their development plans.
Kajian Model Pengembangan Ketahanan Pangan Di Kabupaten Lebak Provinsi Banten
Authors: Hasan Sumarna 
Published: July 2019

Model pengembangan ketahanan pangan di Kabupaten Lebak merupakan arahan pengembangan agribisnis tanaman pangan yang perlu dilaksanakan oleh pemerintah Daerah Kabupaten Lebak, instansi terkait, dan masyarakat. Sebagai acuan dasar, model ini merupakan program/dasar pengembangan agribisnis tanaman pangan, sedangkan pelaksanaannya diserahkan kepada prakarsa masyarakat yang disesuaikan dengan dinamika politik yang berkembang. Tanaman pangan yang sudah dibudidayakan oleh masyarakat di Kabupaten Lebak antara lain tanaman padi sawah, padi gogo, jagung, kacang tanah, kacang kedelai, ubi kayu dan ubi jalar. Komoditi tersebut diusahakan baik dilahan sawah maupun dilahan darat. Potensi komoditas agribisnis tanaman pangan di Kabupaten Lebak diperoleh berdasarkan hasil analisis lokalisasi, spesialisasi dan kekuatan basis serta potensi sumberdaya agribisnis tanaman pangan yang ada di lingkungan Kabupaten Lebak. Hal ini dilakkan untuk mengetahui kecamatan yang menjadi basis komoditas tanaman pangan di Kabupaten Lebak.
Evaluación de cuatro distancias de siembra y dos de deshijas en pejibaye sin espinas
Authors: Bogantes Arias Antonio 
Published: July 2019

Con el objetivo de comparar sistemas de producción de palmito manejados a baja y alta densidad de siembra se hizo este estudio desde enero del 2009 a diciembre del 2011 en una parcela de pejibaye sin espinas de la variedad Diamantes 10 con 11 años de edad. La parcela estaba ubicada en la Estación Experimental Los Diamantes del Instituto Nacional de Innovación y Transferencia en Tecnología Agropecuaria (INTA), situada en Pococí, provincia de Limón. Los tratamientos evaluados fueron la combinación de cuatro distancias de siembra con dos técnicas de manejo de cepa, para un total de ocho combinaciones factoriales. Para la producción de palmitos se analizó la cosecha desde su inicio (año 2001), la cual fue superior en la distancia 0,25 m entre plantas (20 000 plantas ha-1) con una producción promedio de 15 055 palmitos ha-1 y descendió conforme aumentó la distancia con un promedio de 9273 palmitos en la distancia de 1 m entre plantas. Se observó que independiente de la densidad, por cada 100 kg de biomasa fresca cortados, 80 kg se incorporan al sistema (suelo) y 20 kg se van en el palmito extraído. En las parcelas con plantas sembradas a 1 m entre sí, las cepas midieron 0,55x0,42x0,20 m en surelación de largo, ancho y altura respectivamente; mientras que en las parcelas con plantas de nueve años sembradas a 0,25 m entre sí, la cepa ya se había convertido en un surco. Se describieron los hongos Phytophthora sp. y Fusarium sp., los cuales son patogénicos al cultivo y otros seis hongos no patogénicos a las plantas de palmito. La cantidad de lombrices encontradas fue superior en el suelo de las parcelas con plantas a 0,25 m y disminuyó conforme aumentó la distancia entre plantas.
Palabras claves: Bactris gasipaes K., densidad de siembra, cosecha
Analisis Loyalitas Konsumen Ritel Berbasis Swalayan pada Lab Bisnis
Authors: Halilah Ii , Sari Putri Ivon Sandya 
Published: July 2019

The “Lab Bisnis”, which is a Business Administration Dept’s laboratory, is a kind of convenience store. The daily transactions which influence the profit of the store are very low compared with other competitors. This condition might happen because of the low level of customer loyalty. This study found that the customer loyalty factor of Lab Bisnis is high in repeat buying & referrals factors. However, as for the retention behavior, it should be increased by the management. The study can make a module to arrange the loyalty strategy program in next future.
Pengaruh Kualitas Produk kartuHALO Terhadap Kepuasan Pengguna (Studi pada GraPARI Telkomsel MTC Bandung)
Authors: Puspitasari Dita , Tjahjawati Sri Surjani 
Published: July 2019

Every company does business by producing a product or service with good quality. Quality is very important for the company because every company has its own standards based on specifications set. The quality is also very important for consumers because consumers who determine the needs and desires as well as closely related to satisfaction will be felt after using the product. Customer satisfaction is also very important for the company because the company trying to provide something that is needed, desired and sought after by consumers, and ultimately the consumer will be satisfied. Satisfaction is also very important for consumers because it is something to be gained by comparing the expectations of the performance of the products that have been purchased. This study aims to determine the effect on product quality kartuHALO user satisfaction in GraPARI MTC Telkomsel Bandung. The method used in this research is descriptive method, with the results stating that kartuHALO product quality and user satisfaction in GraPARI MTC Telkomsel Bandung is quite good. Of the eight dimensions of the variable product quality, performance dimension had the highest contribution is 4.14 and the dimensions of durability contribute to the bottom at 3.86. For user satisfaction, from the existing three-dimensional, dimensions of emotional factors contribute to the high at 4.02 and dimensions contribute to its lowest price of 3.66. This study used a questionnaire distributed to 270 respondents. Based on the research that has been done, regression equation Y = 7.483 + 0,283X. The study states that kartuHALO product quality and user satisfaction has a strong positive correlation of 0.582 and product quality kartuHALO affect user satisfaction of 33.9%.
Pengaruh Stres Kerja Terhadap Kepuasan Kerja Perawat Di Ruang Rawat Inap Rumah Sakit Krakatau Medika Cilegon
Authors: Widiharti Lisa 
Published: July 2019

Job satisfaction can improve durability individuals to stress and impacts of stress and on the other hand, stress that perceived by an individual can be a source of discontent. This research aims to know the influence of work stress of job satisfaction of nurses in internist room of Krakatau Medika Hospital Cilegon. Research method the used is the descriptive method to 215 nurses who have experienced nurses' room of Krakatau Medika Hospital Cilegon. While to test the research hypothesis, the authorize a simple regresion analysis method with the help of software SPSS 20. The results showed job stress in nurses in the inpatient unit Krakatau Medika Hospital in the moderate category is 2.88 and the job satisfaction of nurses are in a high category. Work stress experienced by nurses at Krakatau Medika Hospital has a positive effect on job satisfaction, so the impact of positive stress is used as a motivational well as improved performance. The results of correlation calculations, the independent variables on satisfaction positive relationships with low classification, the amount of work stress on job satisfaction, which is 12.4% and the remaining 87.6% influenced by other factors not described in this study, other factors such as remuneration, staffing, work environment, leadership style, and so on.