bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geophysical signature of Målingen, the minor crater of the Lockne–Målingen doublet impact structure
Authors: Melero‐Asensio Irene , Ormö Jens , Sturkell Erik , Stockmann Gabrielle , Mansfeld Joakim 
Published: April 2018

AbstractMålingen is the 0.7 km wide minor crater associated to the 10 times larger Lockne crater in the unique Lockne–Målingen doublet. The craters formed at 458 Ma by the impact of a binary asteroid related to the well‐known 470 Ma Main Belt breakup event responsible for a large number of Ordovician craters and fossil meteorites. The binary asteroid struck a target sequence including ~500 m of sea water, ~80 m of limestone, ~30 m of dark mud, and a peneplainized Precambrian crystalline basement. Although the Lockne crater has been extensively studied by core drillings and geophysics, little is known about the subsurface morphology of Målingen. We performed magnetic susceptibility and remanence, as well as density, measurements combined with gravity, and magnetic field surveys over the crater and its close vicinity as a base for forward magnetic and gravity modeling. The interior of the crater shows a general magnetic low of 90–100 nT broken by a clustered set of high‐amplitude, short wavelength anomalies caused by bodies of mafic rock in the target below the crater and as allogenic blocks in the crater infill. The gravity shows a general −1.4 mgal anomaly over the crater caused by low‐density breccia infill and fractured crystalline rocks below the crater floor. The modeling also revealed a slightly asymmetrical shape of the crater that together with the irregular ejecta distribution supports an oblique impact from the east, which is consistent with the direction of impact suggested for the Lockne crater.
A comparison of minimum dietary diversity in Bangladesh in 2011 and 2014
Authors: Blackstone Sarah , Sanghvi Tina 
Published: April 2018

AbstractImproving infant and young child feeding practices is critical for improving growth and reducing child mortality and morbidity. This paper aims to compare predictors of minimum dietary diversity, an important indicator of adequate complementary feeding practices, in Bangladesh in 2011 and 2014. The 2011 and 2014 Bangladesh Demographic and Health Survey were used to examine predictors of minimum dietary diversity among 6–23 months. An additional analysis was conducted for the 18–23‐month group, because a significant increase in meeting minimum dietary diversity recommendations was seen in this age group only. Factors found to be associated with practices were compared across time points. In 2011, minimum dietary diversity was 23.8% and increased to 28.8% in 2014. Among children 18–23 months, in 2011, minimum dietary diversity was 32.5% and increased to 42.8% in 2014. Among all children, wealth, education, exposure to media, and antenatal care were significant predictors of dietary diversity. In the 18–23‐month age group, significant predictors in 2011 were wealth and decision making. In 2014, significant predictors were education and exposure to media. Demographic trends indicated a significant increase in education and exposure to media between 2011 and 2014. As these were significant for minimum dietary diversity in 2014 overall and for 18–23 months, they might be important targets of future interventions, specifically utilizing media channels and tailoring special strategies for women with low education and limited exposure to media.
From transects to transcripts: Teasing apart the architecture of reproductive isolation
Authors: Hamilton Jill A. , Miller Joshua M. 
Published: April 2018

Understanding the processes underlying speciation has long been a challenge to evolutionary biologists. This spurs from difficulties teasing apart the various mechanisms that contribute to the evolution of barriers to reproduction. The study by Rafati et al. () in this issue of Molecular Ecology combines spatially explicit whole‐genome resequencing with evaluation of differential gene expression across individuals with mixed ancestry to associate the genomic architecture of reproductive barriers with expression of reproductive incompatibilities. In a natural hybrid zone between rabbit subspecies, Oryctolagus cuniculus cuniculus and O. c. algirus (Figure ), Rafati et al. () use landscape‐level patterns of allele frequency variation to identify potential candidate regions of the genome associated with reproductive isolation. These candidate regions are used to test predictions associated with the genomic architecture of reproductive barriers, including the role of structural rearrangements, enrichment of functional categories associated with incompatibilities, and the contribution of protein‐coding versus regulatory changes. A lack of structural rearrangements and limited protein‐coding changes in candidate regions point towards the importance of regulatory variation as major contributors to genetic incompatibilities, while functional enrichments indicate overrepresentation of genes associated with male infertility. To quantify phenotypic expression of proposed incompatibilities, the authors assess gene expression of experimental crosses. Extensive misregulation of gene expression within the testes of backcross hybrids relative to F1 and parental individuals provides an important link between genotype and phenotype, validating hypotheses developed from assessment of genomic architectures. Together, this work shows how pairing natural hybrid zones with experimental crosses can be used to link observations in nature to mechanistic underpinnings that may be tested experimentally.
Laminar shear stress modulates endothelial luminal surface stiffness in a tissue‐specific manner
Authors: Merna Nick , Wong Andrew K. , Barahona Victor , Llanos Pierre , Kunar Balvir , Palikuqi Brisa , Ginsberg Michael , Rafii Shahin , Rabbany Sina Y. 
Published: April 2018

AbstractObjectiveEndothelial cells form vascular beds in all organs and are exposed to a range of mechanical forces that regulate cellular phenotype. We sought to determine the role of endothelial luminal surface stiffness in tissue‐specific mechanotransduction of laminar shear stress in microvascular mouse cells and the role of arachidonic acid in mediating this response.MethodsMicrovascular mouse endothelial cells were subjected to laminar shear stress at 4 dynes/cm2 for 12 hours in parallel plate flow chambers that enabled real‐time optical microscopy and atomic force microscopy measurements of cell stiffness.ResultsLung endothelial cells aligned parallel to flow, while cardiac endothelial cells did not. This rapid alignment was accompanied by increased cell stiffness. The addition of arachidonic acid to cardiac endothelial cells increased alignment and stiffness in response to shear stress. Inhibition of arachidonic acid in lung endothelial cells and embryonic stem cell‐derived endothelial cells prevented cellular alignment and decreased cell stiffness.ConclusionsOur findings suggest that increased endothelial luminal surface stiffness in microvascular cells may facilitate mechanotransduction and alignment in response to laminar shear stress. Furthermore, the arachidonic acid pathway may mediate this tissue‐specific process. An improved understanding of this response will aid in the treatment of organ‐specific vascular disease.
Survival rate and population size of Indo‐Pacific humpback dolphins (Sousa chinensis) in Xiamen Bay, China
Authors: Chen Bingyao , Gao Huili , Jefferson Thomas A. , Lu Yi , Wang Lin , Li Shanshan , Wang Hui , Xu Xinrong , Yang Guang 
Published: April 2018

AbstractThe survival rate and population size of Indo‐Pacific humpback dolphins (Sousa chinensis) in Xiamen, China, were estimated from vessel‐based surveys during 2007–2010. Over the course of 202 d (881.1 observation hours), 76 groups were observed, and 52 dolphins were successfully identified. The Cormack‐Jolly‐Seber model estimated a constant apparent survival of 0.948 (95% CI: 0.922–0.966). Based on the open/POPAN model, the population size was estimated at 70 individuals (95% CI: 63–88). To explore the effect of uneven yearly survey effort, we pooled the data with seven sampling occasions with similar effort. This data set generated similar results of a constant survival of 0.957 (95% CI: 0.918–0.978) and population size of 72 (95% CI: 65–88). The small population size of the Xiamen humpback dolphins satisfies the Critically Endangered criterion of IUCN (D), and emphasizes urgency of the need for protection of the population. Improved monitoring efforts should be focused on enhancing our understanding of current status and evaluating impacts of all anthropogenic activities. A conservation plan for the population should also be drawn up.
Risk factors for early invasive fungal infections in paediatric liver transplant recipients
Authors: Pasternak Yehonatan , Rubin Shiri , Bilavsky Efraim , Mozer‐Glassberg Yael , Levy Itzhak , Nahum Elhanan , Rom Eran , Gurevich Michael , Ben‐Zvi Haim , Ashkenazi‐Hoffnung Liat 
Published: April 2018

SummaryInvasive fungal infections (IFIs) postliver transplantation are a frequent cause of morbidity and mortality; however, studies reporting on these infections in the paediatric population are scarce. To investigate the incidence and risk factors of IFIs in paediatric liver transplant recipients during the early posttransplantation period (≤3 months). Data were collected for all paediatric liver transplant recipients registered in a national transplantation center from 2004 to 2014. Using a stepwise logistic regression to identify independent risk factors for IFIs, a predictive model was formulated. Ten IFIs were identified in 81 liver transplant recipients (12.3%) all occurring during the first month posttransplantation. Candida species were responsible for nine cases (90%), of which four were non‐albicans Candida (44%). Significant risk factors were identified; recipient of multiple blood product transfusions during transplantation, prolonged use of indwelling intravenous catheter, prolonged IV antibiotic treatment, surgical complications, pulse steroid treatment and living donor liver transplantation. The predictive model used two clinical parameters to define high‐risk patients: a living donor transplantation and duration of IV antibiotic treatment (area under the ROC curve 0.918). IFIs are a significant complication occurring in the first month posttransplantation. Future studies are required to assess efficacy of targeted antifungal prophylaxis in high risk patients.
Karl Polanyi and the formation of this generation's new Left
Authors: Sandbrook Richard 
Published: April 2018

AbstractAs the democratic Left spirals ever downwards, the worrying forces of populism and neoliberalism seem to be emerging from the ashes. Could the visionary thinking of economic historian Karl Polanyi provide a feasible fix in the 21st Century? An open‐ended approach might be just the ticket to rescue global politics from a far right explosion – and it's not rocket science…
Demographic variance in heterogeneous populations: matrix models and sensitivity analysis
Authors: Caswell Hal , Vindenes Yngvild 
Published: April 2018

The demographic consequences of stochasticity in processes such as survival and reproduction are modulated by the heterogeneity within the population. Therefore, to study effects of stochasticity on population growth and extinction risk, it is critical to use structured population models in which the most important sources of heterogeneity (e.g. age, size, developmental stage) are incorporated as i‐state variables.Demographic stochasticity in heterogeneous populations has often been studied using one of two approaches: multitype branching processes and diffusion approximations. Here, we link these approaches, through the demographic stochasticity in age‐ or stage‐structured matrix population models. We derive the demographic variance, σ2d, which measures the per capita contribution to the variance in population growth increment, and we show how it can be decomposed into contributions from transition probabilities and fertility across ages or stages. Furthermore, using matrix calculus we derive the sensitivity of σ2d to age‐ or stage‐specific mortality and fertility. We apply the methods to an extensive set of data from age‐classified human populations (long‐term time‐series for Sweden, Japan and the Netherlands; two hunter–gatherer populations, and the high‐fertility Hutterites), and to a size‐classified population of the herbaceous plant Calathea ovandensis. For the human populations our analysis reveals substantial temporal changes in the demographic variance as well as its main components across age.These new methods provide a powerful approach for calculating the demographic variance for any structured model, and for analyzing its main components and sensitivities. This will make possible new analyses of demographic variance across different kinds of heterogeneity in different life cycles, which will in turn improve our understanding of mechanisms underpinning extinction risk and other important biological outcomes.
Child's play – an unforeseen complication of surgical emphysema
Authors: Graham C. , Chung M. , Feinberg L. , O'Neill F. , Balmer C. 
Published: April 2018

AbstractSurgical emphysema is as an iatrogenic complication whereby air is dispersed within the tissues following an invasive procedure. It is relatively uncommon, however, it has been recognised that dental extractions and the use of air turbine drills can result in this complication. Here, we discuss a case report of a 35‐year‐old male re‐attending with extensive surgical emphysema following a seemingly uncomplicated dental extraction, caused by playing with his baby. This case was unusual because no dental air turbine drill was used during the dental extraction, and due to the innocuous patient activity that caused the emphysema. Consideration of the aetiology, prevention and recognition of surgical emphysema are discussed.
Atrial fibrillation symptom profiles associated with healthcare utilization: A latent class regression analysis
Authors: Streur Megan M. , Ratcliffe Sarah J. , Callans David J. , Shoemaker M. Benjamin , Riegel Barbara J. 
Published: April 2018

AbstractBackgroundSymptoms drive healthcare use among adults with atrial fibrillation, but limited data are available regarding which symptoms are most problematic and which patients are most at‐risk. The purpose of this study was to: (1) identify clusters of patients with similar symptom profiles, (2) characterize the individuals within each cluster, and (3) determine whether specific symptom profiles are associated with healthcare utilization.MethodsWe conducted a cross‐sectional secondary data analysis of 1,501 adults from the Vanderbilt Atrial Fibrillation Registry. Participants were recruited from Vanderbilt cardiology clinics, emergency department, and in‐patient services. Subjects included in our analysis had clinically verified atrial fibrillation and a completed symptom survey. Symptom and healthcare utilization data were collected with the University of Toronto Atrial Fibrillation Severity Scale. Latent class regression analysis was used to identify symptom clusters, with clinical and demographic variables included as covariates. We used Poisson regression to examine the association between latent class membership and healthcare utilization.ResultsParticipants were predominantly male (67%) with a mean age of 58.4 years (±11.9). Four latent classes were evident, including an Asymptomatic cluster (N = 487, 38%), Highly Symptomatic cluster (N = 142, 11%), With Activity cluster (N = 326, 25%), and Mild Diffuse cluster (N = 336, 26%). Highly Symptomatic membership was associated with the greatest rate of emergency department visits and hospitalizations (incident rate ratio 2.4, P < 0.001).ConclusionsClinically meaningful atrial fibrillation symptom profiles were identified that were associated with increased rates of emergency department visits and hospitalizations.
Why Subjectivists About Welfare Needn't Idealize
Authors: Lin Eden 
Published: April 2018

AbstractIt is commonly thought that subjectivists about welfare must claim that the favorable attitudes whose satisfaction is relevant to your well‐being are those that you would have in idealized conditions (e.g. ones in which you are fully informed and rational). I argue that this is false. I introduce a non‐idealizing subjectivist view, Same World Subjectivism, that accommodates the two main rationales for idealizing: those given by Peter Railton and David Sobel. I also explain why a recent argument from Dale Dorsey fails to show that subjectivists must idealize. Because Same World Subjectivism is a plausible non‐idealizing view, subjectivists about welfare needn't idealize.
QTL epistatic analysis for yield components with single‐segment substitution lines in rice
Authors: Wang Xiaoling , Jin Lingling , Zhu Haitao , Wang Shaokui , Zhang Guiquan , Liu Guifu 
Published: April 2018

AbstractEpistasis is an important genetic component in determining the phenotype of complex quantitative trait. In this article, 12 single‐locus heterozygotes and 66 double‐locus heterozygotes were developed and then were applied to assay QTL epistasis for four yield‐associated traits under two planting densities. Of 264 (66 × 4) tested interactions, 130 (49.2%) were significant at the p < .05 level. QTL with the same effect directions had higher probabilities of interactions. The negative epistasis at least included one positive effect QTL but the positive epistasis one negative QTL. The detected epistasis was sensitive to planting density. Epistasis also exhibited pleiotropic effects.
Mapping of a novel, major late blight resistance locus in the diploid (1EBN) Mexican Solanum pinnatisectum Dunal on chromosome VII
Authors: Nachtigall Marion , König Janine , Thieme Ramona 
Published: April 2018

AbstractLate blight caused by the oomycete Phytophthora infestans (Mont.) de Bary (Pi) is the most important foliar disease of potato worldwide. An intraspecific hybrid between individuals of a resistant and a susceptible S. pinnatisectum accession was backcrossed to the susceptible parent to generate a segregating population for late blight resistance consisting of 84 plants. In detached‐leaflet assays, reaction to late blight segregated in a 1r:1s manner in BC1 progeny indicating the presence of a single dominant resistance gene. A genetic map was constructed based on 1,583 DArT/SSR markers which were allocated to 12 linkage groups, covering 1,793.5 cM with an average marker distance of 1.1 cM. The late blight resistance locus derived from S. pinnatisectum was mapped on chromosome VII. In comparison with the previously reported resistance genes Rpi1 and Rpi2, the new target resistance locus most likely is located on the opposite arm of chromosome VII. Results of this study will serve as a basis for future fine mapping of the late blight resistance locus and the development of locus‐specific markers for marker‐assisted selection.
Climate resilient crops for improving global food security and safety
Authors: Dhankher Om Parkash , Foyer Christine H. 
Published: April 2018

AbstractFood security and the protection of the environment are urgent issues for global society, particularly with the uncertainties of climate change. Changing climate is predicted to have a wide range of negative impacts on plant physiology metabolism, soil fertility and carbon sequestration, microbial activity and diversity that will limit plant growth and productivity, and ultimately food production. Ensuring global food security and food safety will require an intensive research effort across the food chain, starting with crop production and the nutritional quality of the food products. Much uncertainty remains concerning the resilience of plants, soils, and associated microbes to climate change. Intensive efforts are currently underway to improve crop yields with lower input requirements and enhance the sustainability of yield through improved biotic and abiotic stress tolerance traits. In addition, significant efforts are focused on gaining a better understanding of the root/soil interface and associated microbiomes, as well as enhancing soil properties.
Morpho‐anatomical and physiological differences between sun and shade leaves in Abies alba Mill. (Pinaceae, Coniferales): a combined approach
Authors: Dörken Veit Martin , Lepetit Bernard 
Published: April 2018

AbstractMorphology, anatomy and physiology of sun and shade leaves of Abies alba were investigated and major differences were identified, such as sun leaves being larger, containing a hypodermis and palisade parenchyma as well as possessing more stomata, while shade leaves exhibit a distinct leaf dimorphism. The large size of sun leaves and their arrangement crowded on the upper side of a plagiotropic shoot leads to self‐shading which is explainable as protection from high solar radiation and to reduce the transpiration via the lamina. Sun leaves furthermore contain a higher xanthophyll cycle pigment amount and Non‐Photochemical Quenching (NPQ) capacity, a lower amount of chlorophyll b and a total lower chlorophyll amount per leaf, as well as an increased electron transport rate and an increased photosynthesis light saturation intensity. However, sun leaves switch on their NPQ capacity at rather low light intensities, as exemplified by several parameters newly measured for conifers. Our holistic approach extends previous findings about sun and shade leaves in conifers and demonstrates that both leaf types of A. alba show structural and physiological remarkable similarities to their respective counterparts in angiosperms, but also possess unique characteristics allowing them to cope efficiently with their environmental constraints.
Circadian rhythms are associated with variation in photosystem II function and photoprotective mechanisms
Authors: Yarkhunova Yulia , Guadagno Carmela R. , Rubin Matthew J. , Davis Seth J. , Ewers Brent E. , Weinig Cynthia 
Published: April 2018

AbstractThe circadian clock regulates many aspects of leaf gas supply and biochemical demand for CO2, and is hypothesized to improve plant performance. Yet the extent to which the clock may regulate the efficiency of photosystem II (PSII) and photoprotective mechanisms such as heat dissipation is less explored. Based on measurements of chlorophyll a fluorescence, we estimated the maximum efficiency of PSII in light (Fv′/Fm′) and heat dissipation by nonphotochemical quenching (NPQ). We further dissected total NPQ into its main components, qE (pH‐dependent quenching), qT (state‐transition quenching), and qI (quenching related to photoinhibition), in clock mutant genotypes of Arabidopsis thaliana, the cognate wild‐type genotypes, and a panel of recombinant inbred lines expressing quantitative variation in clock period. Compared with mutants with altered clock function, we observed that wild‐type genotypes with clock period lengths of approximately 24 hr had both higher levels of Fv′/Fm′, indicative of improved PSII function, and reduced NPQ, suggestive of lower stress on PSII light harvesting complexes. In the recombinant inbred lines, genetic variances were significant for Fv′/Fm′ and all 3 components of NPQ, with qE explaining the greatest proportion of NPQ. Bivariate tests of association and structural equation models of hierarchical trait relationships showed that quantitative clock variation was empirically associated with Fv′/Fm′ and NPQ, with qE mediating the relationship with gas exchange. The results demonstrate significant segregating variation for all photoprotective components, and suggest the adaptive significance of the clock may partly derive from its regulation of the light reactions of photosynthesis and of photoprotective mechanisms.