bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical outcomes of pallidal deep brain stimulation for dystonia implanted using intraoperative MRI
Authors: Sharma Vibhash D. , Bezchlibnyk Yarema B. , Isbaine Faical , Naik Kushal B. , Cheng Jennifer , Gale John T. , Miocinovic Svjetlana , Buetefisch Cathrin , Factor Stewart A. , Willie Jon T. , Boulis Nicholas M. , Wichmann Thomas , DeLong Mahlon R. , Gross Robert E. 
Published: October 2019

OBJECTIVELead placement for deep brain stimulation (DBS) using intraoperative MRI (iMRI) relies solely on real-time intraoperative neuroimaging to guide electrode placement, without microelectrode recording (MER) or electrical stimulation. There is limited information, however, on outcomes after iMRI-guided DBS for dystonia. The authors evaluated clinical outcomes and targeting accuracy in patients with dystonia who underwent lead placement using an iMRI targeting platform.METHODSPatients with dystonia undergoing iMRI-guided lead placement in the globus pallidus pars internus (GPi) were identified. Patients with a prior ablative or MER-guided procedure were excluded from clinical outcomes analysis. Burke-Fahn-Marsden Dystonia Rating Scale (BFMDRS) scores and Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS) scores were assessed preoperatively and at 6 and 12 months postoperatively. Other measures analyzed include lead accuracy, complications/adverse events, and stimulation parameters.RESULTSA total of 60 leads were implanted in 30 patients. Stereotactic lead accuracy in the axial plane was 0.93 ± 0.12 mm from the intended target. Nineteen patients (idiopathic focal, n = 7; idiopathic segmental, n = 5; DYT1, n = 1; tardive, n = 2; other secondary, n = 4) were included in clinical outcomes analysis. The mean improvement in BFMDRS score was 51.9% ± 9.7% at 6 months and 63.4% ± 8.0% at 1 year. TWSTRS scores in patients with predominant cervical dystonia (n = 13) improved by 53.3% ± 10.5% at 6 months and 67.6% ± 9.0% at 1 year. Serious complications occurred in 6 patients (20%), involving 8 of 60 implanted leads (13.3%). The rate of serious complications across all patients undergoing iMRI-guided DBS at the authors’ institution was further reviewed, including an additional 53 patients undergoing GPi-DBS for Parkinson disease. In this expanded cohort, serious complications occurred in 11 patients (13.3%) involving 15 leads (10.1%).CONCLUSIONSIntraoperative MRI–guided lead placement in patients with dystonia showed improvement in clinical outcomes comparable to previously reported results using awake MER-guided lead placement. The accuracy of lead placement was high, and the procedure was well tolerated in the majority of patients. However, a number of patients experienced serious adverse events that were attributable to the introduction of a novel technique into a busy neurosurgical practice, and which led to the revision of protocols, product inserts, and on-site training.
Racial phenotypes in moyamoya disease: a comparative analysis of clinical presentation and natural history in a single multiethnic cohort of 250 hemispheres
Authors: Feghali James , Xu Risheng , Yang Wuyang , Liew Jason , Tamargo Rafael J. , Marsh Elisabeth B. , Huang Judy 
Published: October 2019

OBJECTIVEThe authors aimed to determine whether differences exist in presentation and natural history when comparing Asian patients with moyamoya disease (MMD) to those of other ethnicities in North America.METHODSA database of 137 patients with MMD presenting to their institution between 1994 and 2015 was reviewed. Baseline characteristics and outcome variables, including stroke and functional outcome, were compared between Asian and non-Asian patients. Unadjusted Kaplan-Meier survival analysis and adjusted Cox regression models were used to compare stroke-free survival and stroke hazard after diagnosis among hemispheres of both racial groups. The analysis was stratified by age group, and censoring was performed until last follow-up or at the time of surgery. Because the relative rate of stroke changed between Asian and non-Asian adults after 1.5 years of follow-up, a time-segmented analysis focusing on the period 1.5 years after diagnosis was performed.RESULTSThe cohort comprised 23% (31/137) Asian and 77% (106/137) non-Asian patients with MMD with a bimodal age distribution. Non-Asian patients had a higher prevalence of increased BMI (p = 0.02) and smoking (p = 0.04). Among patients who presented with stroke (n = 90), hemorrhage was significantly more common among Asians (p = 0.02). The natural history analysis included 250 hemispheres: 67 pediatric and 183 adult hemispheres. The overall mean follow-up duration since diagnosis was 3.3 years. Among adults, Asian patients had a higher incidence of stroke (8.0 per 100 person-years vs 3.0 per 100 person-years) over a mean follow-up of 3.3 years, but results were not statistically significant (p = 0.45). In the period beginning 1.5 years after diagnosis, Asian adults had a significantly higher hazard of stroke over a mean follow-up of 7.7 years, while controlling for sex, hypertension, and stroke before diagnosis (hazard ratio 8.8, p = 0.02). Among pediatric patients, Asians also had a higher stroke incidence (10.0 per 100 person-years vs 3.5 per 100 person-years) over a mean follow-up of 3.2 years; however, results did not reach statistical significance (p = 0.40). Functional outcome was similar between both ethnic groups at last follow-up (p = 0.57).CONCLUSIONSThis study suggests a comparatively more progressive course of MMD in Asians. Further studies are required to fully characterize the phenotypic distinctions between different races and underlying pathophysiological mechanisms.
Prevention of neointimal hyperplasia induced by an endovascular stent via intravenous infusion of mesenchymal stem cells
Authors: Nakazaki Masahito , Oka Shinichi , Sasaki Masanori , Kataoka-Sasaki Yuko , Onodera Rie , Komatsu Katsuya , Iihoshi Satoshi , Hiroura Manabu , Kawaguchi Akira , Kocsis Jeffery D. , Honmou Osamu 
Published: October 2019

OBJECTIVEIn-stent restenosis after percutaneous transluminal angioplasty and stenting (PTAS) due to neointimal hyperplasia is a potential cause of clinical complications, including repeated revascularization and ischemic events. Neointimal hyperplasia induced by an inflammatory response to the stent strut may be a possible mechanism of in-stent restenosis. Intravenous infusion of bone marrow–derived mesenchymal stem cells (MSCs) has been reported to show therapeutic efficacy for cerebral stroke, presumably by an antiinflammatory effect. This study aimed to determine whether MSCs can reduce or prevent neointimal hyperplasia induced by an endovascular stent.METHODSIn this study, two types of bare metal stents were deployed using a porcine (mini-pig) model. One stent was implanted in the common carotid artery (CCA), which is considered quite similar to the human CCA, and the other was inserted in the superficial cervical artery (SCA), which is similar in size to the human middle cerebral artery. Angiographic images, intravascular ultrasound (IVUS) imaging, and microscopic images were used for analysis.RESULTSAngiographic images and IVUS studies revealed that intravenous infusion of MSCs immediately after deployment of stents prevented in-stent stenosis of the CCA and SCA. Histological analysis also confirmed that inflammatory responses around the stent struts were reduced in both the stented CCA and SCA in the mini-pig.CONCLUSIONSIntravenous infusion of MSCs inhibited the inflammatory reaction to an implanted stent strut, and prevented progressive neointimal hyperplasia in the stented CCA and SCA in a porcine model. Thus, MSC treatment could attenuate the recurrence of cerebral ischemic events after stenting.
ANALISIS KINERJA PENGGUNAAN RADIO FREQUENCY IDENTIFICATION (RFID) DAN QUICK RESPONSE CODE (QR CODE) PADA PENCARIAN DATA MEDIS
Authors: Sufri Rahmat , Away Yuwaldi , Munadi Rizal 
Published: October 2019

<p>Teknologi terbaru yang dapat diterapkan untuk identifikasi yaitu <em>Radio Frequency Identification</em> (RFID) yang merupakan sistem identifikasi tanpa kabel bisa melakukan pengambilan data dengan cepat, mudah tanpa harus bersentuhan dan dapat digunakan untuk operasi otomatis. Sistem RFID terdiri dari tag, pembaca, middleware, aplikasi program dan server. Seiringin perkembangannya muncul juga teknologi pilihan lain yaitu QR Code atau <em>Quick Respon Code</em> dalam mengatasi masalah identifikasi data menjadi efektif dan cepat. Untuk mengakses informasi <em>QR Code</em> berbeda dengan teknologi RFID yang membutuhan perangkat khusus atau <em>reader</em> sebagai pembaca tag melainkan sangat mudah hanya membutuhkan perangkat camera atau <em>webcam</em> kemudian difokuskan QR Code pada kamera dan akan langsung terbaca dengan cepat. Saat ini dalam mengidentifikasi data medis masih dilakukan secara konvensional yaitu mengetik nomor ID dengan keyboard maka ada kemungkinan terjadi kesalahan dan membutuhkan waktu yang lama sehingga tidak efesien, untuk mengatasi masalah tersebut menggunakan RFID dan QR Code adalah solusi yang tepat, dengan RFID dan QR Code hanya cukup menempelkan pada RFID reader selanjutnya kode akan dilakukan pecarian langsung secara otomatis. Manfaat yang diperoleh pada penelitian ini adalah mengetahui perbandingan RFID dan QR Code melakukan pencarian data medis, dan dapat mengidentifikasi pencarian data medis dengan lebih mudah, cepat dan akurat.</p>
Pengembangan Majalah Anatomi Tumbuhan Sebagai Sumber Informasi Mahasiswa di IKIP Budi Utomo Malang
Authors: Arifin As'ad Syamsul , Riyanto Riyanto 
Published: October 2019

Penelitian ini untuk mengembangkan bahan ajar berupa majalah guna mendukung berhasilnya proses pembelajaran anatomi tumbuhan. Hadirnya majalah anatomi tumbuhan diharapkan dapat memberikan suasana belajar yang baru selama proses belajar, serta mampu memberikan informasi terbaru. Model pengembangan dalam penelitian ini menggunakan model 4D dari Thiagarajan (1974). Model 4D memiliki 4 tahapan antaralain: define, design, develop, dan disseminate, tetapi dalam penelitian ini hanya dilakukan sampai tahap develop saja tanpa tahap disseminate. Sampel yang digunakan dalam uji coba adalah mahasiswa kelas A angkatan 2017 berjumlah 35 orang, data diperoleh dengan menggunakan hasil angket. Hasil penelitian menunjukkan pengembangan bahan ajar Majalah layak digunakan dalam pembelajaran, ini ditunjukkan hasil data uji ahli materi dinyatakan sangat baik, data uji media dan desain pembelajaran dinyatakan sangat baik, data uji coba perorangan dinyatakan sangat baik dan uji coba kelompok sedang dinyatakan sangat baik. Uji coba kelompok sedang dapat disimpulkan bahwa bahan ajar Majalah layak digunakan sebagai salah satu reverensi majalah bahan ajar Anatomi Tumbuhan oleh mahasiswa IKIP Budi Utomo Malang karena sudah tervalidasi.
Demonetization and Its Effects on BSESENSEX and Some Sectoral Indices: An Exploratory Econometric Analysis
Authors: MUKHOPADHYAY Debabrata , SARKAR Nityananda 
Published: October 2019

This study has carried out somepreliminary
time series analyses to examine the impacts of demonetization which was carried
outin India on 8 November 2016, on the well-known Indian stock index,
BSESENSEX,and four major sectoral indices viz., BSE BANKEX,BSE Auto, BSE Reality
and BSE Smallcap,using daily level time series data covering the period 1January
2016 to 31May2017. Apart from examining the stationarity/nonstationarity
property and existence of structural breaks after demonetizationin these series,
the paper has also studied the trend behavior and returns models for both the
pre- and post-demonetization periods. This study has
found that while there is more than one break in all the five series at their
level values, there is only one structural break after demonetization. It has also been found that the trend
function for all the index series broadly gives support to this finding of one break
after demonetization. Further, some changes have also been observed in the
stationary models for the two sub-periods of pre- and post-demonetization for
all but BSE Auto index. Finally, except for BSESENSEX to some extent, no change
in the status of stationarity/nonstationarity in the pre- and post-
demonetization periods has been found in the other series.
Peningkatan Hasil Belajar Pendidikan Agama Islam tentang Menerima Qada’ dan Qadar melalui Pendekatan Saintifik bagi Siswa Kelas VI di SD Inpres 33 Kabupaten Sorong
Authors: Syaida Syaida 
Published: October 2019

Penelitian ini bertujuan untuk mengetahui Peningkatan Hasil Belajar Pendidikan Agama Islam Sub tema Menerima Qada’ Dan Qadar Melalui Pendekatan Saintifik. Subyek penelitian adalah seluruh siswa kelas VI pada Semester Genap Tahun Pelajaran 2015/2016 dengan siswa sebanyak 20 orang, terdiri dari 9 orang laki-laki dan 11 orang perempuan. Pengumpulan data dilaksanakan dengan menggunakan Tes Akhir Siklus dan Observasi. Data yang terkumpul dianalisis dengan menggunakan analisis kualitatif dan kuantitatif. Hasil belajar Pendidikan Agama Islam siswa kelas VI pada Semester Genap Tahun Pelajaran 2015/2016 meningkat setelah dilakukan pembelajaran dengan pendekatan saintifik selama dua siklus dengan hasil sebagai berikut : (1) Hasil belajar Pendidikan Agama Islam siswa sebelum pembelajaran dengan pendekatan Saintifik berada dalam kategori rendah dengan nilai rata-rata 62,5 dari nilai tertinggi 70 dan nilai terendah 50. (2) Hasil belajar Agama siswa setelah pembelajaran Siklus I dengan pendekatan saintifik dengan nilai rata-rata 72.5 dari nilai tertinggi 90 dan nilai terendah 60. (3). Hasil belajar Agama siswa setelah pembelajaran dengan pendekatan Saintifik Siklus II berada dalam kategori sedang dengan nilai rata-rata 84,5 dari nilai tertinggi 100 dan nilai terendah 65. (4) Terjadi peningkatan kehadiran siswa dalam kegiatan belajar mengajar, dan (5) Terjadi peningkatan motivasi belajar Pendidikan Agama Islam.
Tranceiver Data Tanpa Kabel Dalam Pengendalian Peralatan Elektronik Berbasis Mikrokontroler AT89S51
Authors: Allwine Allwine , Lubis Mhd. Dicky Syahputra 
Published: October 2019

ABSTRAK
Penggunaan teknologi telekomunikasi sebagai sistem kendali jarak jauh memungkinkan seseorang dapat melakukan pengendalian terhadap suatu objek tanpa harus mendekati objek atau peralatan yang akan dikendalikan tersebut. Beranjak dari kenyataan inilah maka muncul suatu keinginan penulis untuk membuat suatu alat yang dapat mengendalikan peralatan elektronika seperti lampu dan kipas angin dari jarak jauh dengan menggunakan Mikrokontroler AT89S51 sebagai unit pengendali utama, sehingga kita bisa mengaktif atau menon-aktifkan suatu peralatan elektronika tanpa harus mendekati peralatan tersebut.
Sistem tranceiver data tanpa kabel berbasis Mikrokontroler AT89S51 secara keseluruhan yang terdiri dari input berupa pemancar dan penerima, kemudian mengirimkan data ke sistem minimum mikrokontroler AT89S51 dan menghasilkan keluaran yang akan menggerakkan relay dalam menghidupkan atau mematikan peralatan listrik.
Sistem ini memanfaatkan Mikrokontroller yang mampu menerima input dari remote dan mengolahnya kemudian mengirimkan data tersebut untuk mengaktifkan relay sehingga peralatan elektronik dapat dikendalikan.

Kata kunci : Transceiver, Mikrokontroler, AT89S51, BASCOM-8051
Kompensasi dan Komunikasi Kerja Berpengaruh Terhadap Kepuasan Kerja
Authors: Budiana Deni 
Published: October 2019

Tujuan dari penelitian ini adalah untuk menganalisa kompensasi, komunikasi kerja berpengaruh terhadap kepuasan kerja. Adapun objek p enelitian yang dipilih dalam studi kasus ini adalah Staf Kolektor PT BPR Karyajatnika Sadaya Wilayah Bandung Raya. Jumlah sampel yang diambil sebanyak 412 responden. Pengumpulan data penelitian menggunakan Penelitian Kepustakaan ( Library Research ) dan Penelitian Lapangan ( Field Research ). Metode Analisa Data yang digunakan Desktiftip da n Verifikatif. Analisa Data yang dipakai adalah Analisa Jalur ( Path Analysis ) sebesar 0,635 atau sebesar 63,5% dimana nilai tersebut diperoleh dari penjumlahan pa rsial masing-masing variabel (0,413 + 0,222). Jadi dalam penelitian ini 63,5% kepuasan ke rja karyawan dipengaruhi oleh kompensasi dan komunukasi kerja.
Corneal Cross-linking in Thin Corneas: 1-Year Results of Accelerated Contact Lens–Assisted Treatment of Keratoconus
Authors: Knyazer Boris , Kormas Ran Matlov , Chorny Alexander , Lifshitz Tova , Achiron Asaf , Mimouni Michael 
Published: October 2019

PURPOSE:
To evaluate the safety and efficacy of accelerated contact lens–assisted cross-linking (A-CACXL) for patients with keratoconus and thin corneas.

METHODS:

This retrospective study included consecutive patients undergoing A-CACXL for progressive keratoconus from 2015 to 2017. Patients with a minimum corneal thickness of 400 µm or less after epithelium removal who underwent A-CACXL (9 mW/cm
2
for 10 minutes, using iso-osmolar 0.1% riboflavin solution and a 90-µm thick, daily disposable bandage soft contact lens) with a follow-up time of 12 months or more were included. The main outcome measures were uncorrected (UDVA) and corrected (CDVA) distance visual acuity and minimum corneal thickness at the last visit. Progression (increase) and flattening (decrease) were defined as a change of 1.00 diopters (D) or greater in maximum keratometry or 1.50 D or greater in mean keratometry.

RESULTS:

Overall, 24 eyes of 24 patients were included with a follow-up time of 18.2 ± 6.3 months and a mean minimum corneal thickness, after epithelial debridement, of 353.13 µm. There was a significant improvement in UDVA (
P
= .009), maximum keratometry (
P
= .03), anterior steep keratometry (
P
= .04), anterior astigmatism (
P
= .02), and posterior astigmatism (
P
= .04) with no significant change in minimum corneal thickness (
P
= .11). There was a significant improvement in UDVA (0.90 ± 0.63 to 0.64 ± 0.47 logMAR,
P
= .009), maximum keratometry (61.20 ± 6.30 to 59.90 ± 5.70 D,
P
= .03), anterior steep keratometry (55.10 ± 3.90 to 54.50 ± 4.10 D,
P
= .04), anterior astigmatism (5.50 ± 2.40 to 4.60 ± 2.10 D,
P
= .02), and posterior astigmatism (0.90 ± 0.40 to 0.80 ± 0.40 D,
P
= .04) with no significant change in minimum corneal thickness (from 399.8 ± 30.7 to 391.0 ± 43.8 μm,
P
= .11). Flattening occurred in 45.8% (n = 11) and progression in 20.8% (n = 5). There were no serious adverse events. Persistent clinically significant stromal haze occurred in one case and completely resolved by 6 months. There was no significant change in endothelial cell density (
P
= .10).

CONCLUSIONS:
In patients with keratoconus and thin corneas, A-CACXL halted keratoconus progression in 80%, led to flattening in 45%, and significantly improved UDVA and keratometry values without any evidence of damage to the corneal endothelium or permanent adverse events.

[
J Refract Surg.
2019;35(10):642–648.]
Analysis of Vaccination Rates of 23-Valent Pneumococcal Polysaccharide Vaccine after Quality Improvement Project in Hospitalized Patients with Diabetes Mellitus
Authors: Seagroves Amy , Reh Christina S. , Bischoff Nathaniel , Nally Laura , Singh Jasjit 
Published: October 2019

Abstract
Introduction: Since 2014, the American Academy of Pediatrics has recommended that patients over two years with diabetes mellitus (DM) receive the 23-valent pneumococcal polysaccharide vaccine (PPSV23). Methods: Retrospective chart review was initiated by a quality improvement (QI) project to determine PPSV23 administration rates for inpatients with DM at Children's Hospital of Orange County (CHOC). The QI project included education for staff and families regarding need for PPSV23 in patients with DM. Electronic medical record (EMR) order sets for DM were updated with PPSV23 vaccine. Data were collected from EMR to identify differences in subjects who were vaccinated with PPSV23 and unvaccinated from April 2015 to April 2016. Results: Before April 2015, PPSV23 was not being given to inpatients with DM. There were 199 individual subjects admitted to CHOC with DM from April 2015 to April 2016. Of those, 78 subjects (39.1%) received vaccine. Data were categorized to identify if vaccine was ordered (n = 152) or not (n = 47). Univariate logistic regression analysis performed on whether PPSV23 was ordered showed age, location (pediatric intensive care unit [PICU] vs. floor), hemoglobin A1c (HbA1c), primary DM admission, and insulin pump vs. injection usage were significant factors (P &lt; 0.05). Multivariate logistic regression showed that those with higher HbA1c (P = 0.014), new-onset DM (P = 0.009), and those admitted for primary DM-related issues (P = 0.007) were more likely to have PPSV23 ordered. No significant subject factors identified differences in why vaccine was not administered (n = 74) once ordered. Conclusion: PPSV23 rates for pediatric inpatients with DM increased from 0% to 39% during one year following education and EMR modifications.
Microwave drying of corn seeds: Effect of Temperature on Drying Time, Energy Consuption and Germination Rate
Authors: Hernández Moreno Ángel , Hernández-Maqueda Rafael , Ballesterios Isabel , Torres-Miño Carlos 
Published: October 2019

Previous studies on the microwave drying of corn seeds have shown that the process parameters employed play a very important role in determining the properties and quality of this grain (Gürsoy et al, 2013). Among these parameters, the drying temperature has a fundamental role (Nair et al, 2011). The main objective of this work is to evaluate the effect of temperature on drying time, energy consumption and germination rate of corn seeds after they have been dried with microwave energy. To achieve the proposed objective, the drying process of these seeds was carried out in a rotating turntable domestic microwave oven (LACOR Model 69330), with a capacity of 30 liters and a total output power of 900 W, fitted with a PID temperature controller Eurotherm 3216 L. In this oven, 100 g of corn seeds, with an initial humidity of approximately 20%, was heated up to 3 drying temperatures (35, 55 and 75 °C). The seeds were weighed every 30 minutes and the drying process was considered completed when a humidity of 12 % was obtained. For each drying temperature studied, the experiments were carried out in duplicate. In each experiment, the electrical energy consumption was measured using a FLUKE 1735 energy analyzer. A sample of the dried seeds was subject to germination tests in a petri dish using filter paper and a volume of distillate water of 20mL to achieve sufficient humidity for them to sprout. Table 1 shows the average values obtained from the variables evaluated for each drying temperature. Table 1. Results of the microwave drying experiments of the corn seeds at different temperatures and their germination tests. Drying temperature (ºC) Drying time to reach a humidity of 12% (min) Energy consumption (Wh) Germination rate (%) 35 345,0 880,3 90,0 55 118,5 330,0 81,3 75 73,5 183,9 12,0 As can be seen in Table 1, the temperature exerts a significant influence on the drying process and the germination rate of the corn seeds. An increase in the drying temperature causes a simultaneous decrease in drying time (∿ 78%) and in energy consumption (∿ 79%), which are very positive aspects. However, there is also an unacceptable decrease (∿ 87%) in the germination rate of the corn seeds. References Gürsoy, S., Choudhary, R., Watson, D.G. Int. J Agric. &amp; Biol. Eng., 2013, 6, 1, 90–99.Nair, G.R., Li, Z., Gariepy, Y., Raghavan, V. Drying Technology, 2011, 29, 11, 1291-1296.