bluuebunny/crossref_metadata_2025_split huggingface dataset:
Household fuel use, smoking and prevalence of self-reported allergic rhinitis in university students in Palestine: a cross-sectional study
Authors: El Sharif Nuha , Hnaihen Lana 
Published: November 2024

PurposeIn Palestine, few studies investigated the prevalence of allergies and the factors associated with their occurrence. An online survey was conducted on health complex University students in Jerusalem to determine the prevalence of allergy rhinitis (AR) and its relationship with indoor environmental exposures.MethodsThis study employed a modified online Google form of the Global Asthma Network's Adult Questionnaire. The data were reported as frequency and percentage. The chi-square test of independence was performed to investigate the association between AR diagnosis and other factors. Multivariable models were used to identify the independent risk factors for AR after adjusting for potential confounders.ResultsData was collected from a total of 819 participants. The mean age of the participants was 20 ± 2 years and 78.1% (n = 640) were females. The AR diagnostic rate was 10.3%. In addition, having asthma and eczema were found to be substantially associated with AR. Additionally, a family history of AR and other allergens were major predictors of AR. The findings revealed that utilizing animal dung for heating increased the likelihood of AR fourfold (AOR = 4.870, p-value = 0.004), whereas e-cigarette vaping increased the possibility of AR by 2.5 times. However, using natural gas for cooking was not significantly associated with AR, and participant age was only slightly associated with AR diagnosis.ConclusionsOur study found that the AR prevalence rate is low when compared to the same population in other countries. Genetics, biomass fuel consumption, and e-smoking are all significant risk factors for AR in Palestine. An awareness campaign must be developed to educate university students and the general public about the risks of smoking, indoor air pollution, respiratory disorders, and AR. Longitudinal research is required to discover whether these associations are only transient.
Catheter ablation for atrial tachycardia in pediatric patients: a single-center experience
Authors: Chen Ruoyu , Xu Xin , He Shuang , Liu Qian , Liu Lin , Zhang Qin , Lu Tiewei 
Published: November 2024

PurposeAtrial tachycardia is an uncommon supraventricular tachycardia in children. It is often drug-resistant and likely to occur concomitantly with tachycardia-induced cardiomyopathy, making radiofrequency catheter ablation the preferred treatment. The aim of this study was to assess the feasibility, safety, and effectiveness of radiofrequency catheter ablation for the treatment of different types of atrial tachycardia in children, particularly in those with drug-resistant and tachycardia-induced cardiomyopathy.MethodsA total of 28 children with atrial tachycardia (including focal atrial tachycardia and atrial flutter) who underwent atrial radiofrequency ablation at the Children's Hospital Affiliated to Chongqing Medical University from May 2018 to December 2023 were included. The baseline characteristics, preoperative medication, surgical information, and postoperative follow-up data of these children were analyzed statistically.ResultsThe mean age patients at ablation was 10.24 ± 3.40 years. A total of 78.6% of the patients (22/28) who received preoperative pharmacological treatment had intermittent or persistent atrial tachycardia. Of the 28 children who underwent radiofrequency ablation, 24 (85.7%) were diagnosed with focal atrial tachycardia, three (10.7%) with atrial flutter, and one (3.6%) with both. No postoperative complications occurred in any patient. The immediate ablation success rate in the 25 patients with focal atrial tachycardia was 96.0% (24/25). After 26.89 ± 18.17 months of follow-up, only three patients had recurrence. The ablation difficulty of focal atrial tachycardia originating in the appendage was higher than that originating in the non-atrial appendage (44.4% vs. 6.3%, p = 0.01). The success rate of ablation for atrial flutter was 100%, except in one child with underlying cardiomyopathy who experienced recurrence. Final success was achieved in 25 of the 28 patients (89.2%) at the end of the follow-up period. In addition, eight children (28.6%) in this study were diagnosed with tachycardia-induced cardiomyopathy, with significantly increased ejection fraction and shortening rate after radiofrequency ablation (p &lt; 0.01), whereas the left ventricular end-systolic diameter were not significantly reduced during the follow-up period (p &gt; 0.05).ConclusionRadiofrequency catheter ablation is safe and effective for the treatment of atrial tachycardia in children in the short- and long-term.It can be used as the first treatment option for children with medically refractory atrial tachycardia and tachycardia-induced cardiomyopathy.
Salvage of cardiopulmonary collapse caused by ethanol sclerotherapy for vascular malformations: clinical experience at a single center and literature review
Authors: Su Lixin , Zhao Yan , Shen Yuchen , Fan Xindong , Wang Zhenfeng , Wang Deming , Li Qingyang 
Published: November 2024

ObjectiveThis review aims to summarize the salvage experience of cardiopulmonary collapse occurring as a result of absolute ethanol sclerotherapy for vascular malformations.MethodsIn total, we reviewed three cases of cardiopulmonary collapse induced by ethanol sclerotherapy for vascular malformations and described the details of the salvage procedure. Saturation of pulse oxygen (SpO2), end-tidal CO2, and invasive arterial pressure were the routine monitors for ethanol injection patients. Cardiopulmonary resuscitation, epinephrine, norepinephrine, and deoxyepinephrine were mainly used to correct circulation parameters. Manually ventilated via endotracheal intubation with 100% O2, increased respiratory rate were mainly used to correct Respiratory parameters.ResultsAll three cases were successfully salvaged without major complications. When cardiopulmonary collapse occurred, manual ventilation via endotracheal intubation with 100% O2, increased ventilation frequency and external cardiac compression were the emergency treatments. Epinephrine, norepinephrine, deoxyepinephrine infusion solely or combined were crucial to maintaining the basic vital signs.ConclusionDespite the severity of cardiopulmonary collapse caused by ethanol sclerotherapy, it can be detected by close observation and reversed with timely treatment.
Predictors of beginning teachers’ teaching performance
Authors: Bacus Remedios C. , Picardal Marchee T. , Perez Noremay B. , Balo Vincent Theodore M. 
Published: November 2024

IntroductionQuality education hinges on teacher quality. The multifaceted nature of teachers’ roles and their teaching performance necessitates a comprehensive exploration of factors influencing overall education quality.MethodsThis study employed a regression research design, utilizing an expert-validated survey questionnaire completed by 2,680 beginning teachers from the Department of Education across 16 regions in the Philippines. The study aimed to identify personal, educational, and professional characteristics that predict teaching performance as measured by the Results-based Performance Management System (RPMS).ResultsThe analysis revealed that among various characteristics, socioeconomic status (personal), grade point average (educational), and both the grade level taught and length of service (professional) were significant predictors of teaching performance.DiscussionThe findings underscore the need for teacher education institutions to adapt curricular delivery in a manner that reflects the practical realities of teaching and acknowledges situated learning. Recommendations include the development of quality assurance mechanisms, academic coaching and mentoring programs, and initiatives to strengthen financial literacy among pre-service teachers to enhance their future teaching performance.
Personalized nutrition in type 2 diabetes remission: application of digital twin technology for predictive glycemic control
Authors: Shamanna Paramesh , Joshi Shashank , Thajudeen Mohamed , Shah Lisa , Poon Terrence , Mohamed Maluk , Mohammed Jahangir 
Published: November 2024

BackgroundType 2 Diabetes (T2D) is a complex condition marked by insulin resistance and beta-cell dysfunction. Traditional dietary interventions, such as low-calorie or low-carbohydrate diets, typically overlook individual variability in postprandial glycemic responses (PPGRs), which can lead to suboptimal management of the disease. Recent advancements suggest that personalized nutrition, tailored to individual metabolic profiles, may enhance the effectiveness of T2D management.ObjectiveThis study aims to present the development and application of a Digital Twin (DT) technology—a machine learning (ML)-powered platform designed to predict and modulate PPGRs in T2D patients. By integrating continuous glucose monitoring (CGM), dietary data, and other physiological inputs, the DT provides individualized dietary recommendations to improve insulin sensitivity, reduce hyperinsulinemia, and support the remission of T2D.MethodsWe developed a sophisticated DT platform that synthesizes real-time data from CGM, dietary logs, and other biometric inputs to create personalized metabolic models for T2D patients. The intervention is delivered via a mobile application, which dynamically adjusts dietary recommendations based on predicted PPGRs. This methodology is validated through a randomized controlled trial (RCT) assessing its impact on various metabolic markers, including HbA1c, metabolic-associated fatty liver disease (MAFLD), blood pressure, body weight, ASCVD risk, albuminuria, and diabetic retinopathy.ResultsPreliminary data from the ongoing RCT and real-world study demonstrate the DT’s capacity to generate significant improvements in glycemic control and metabolic health. The DT-driven personalized nutrition plan has been associated with reductions in HbA1c, enhanced beta-cell function, and normalization of hyperinsulinemia, supporting sustained T2D remission. Additionally, the DT’s predictions have contributed to improvements in MAFLD markers, blood pressure, and cardiovascular risk factors, highlighting its potential as a comprehensive management tool.ConclusionThe DT technology represents a novel and scalable approach to personalized nutrition in T2D management. By addressing individual variability in PPGRs, this method offers a promising alternative to conventional dietary interventions, with the potential to improve long-term outcomes and reduce the global burden of T2D.
Effects of oyster shell addition on shrimp aquaculture and the dynamic succession of surface biofilm microbial communities
Authors: Huang Xianke , Xiao Guoqiang , Zhang Xiang , Teng Shuangshuang , Li Min , Cai Yilong , Chen Ran , Huang Xiaolin 
Published: November 2024

IntroductionIn the context of Litopenaeus vannamei aquaculture, the incorporation of oyster shells has proven beneficial for enhancing water quality and the growth conditions of the shrimp. Nonetheless, the specific effects of in-situ water treatment using oyster shells on water quality and shrimp growth, along with the composition and succession dynamics of the microbial community within oyster shell biofilms, have yet to be thoroughly investigated.MethodsThis study established control, low-concentration, and high-concentration oyster shell addition groups to emulate the in-situ water treatment environment with oyster shells, with the objective of elucidating the impacts of oyster shell addition on the aquaculture setting.ResultsThe results showed that the addition of oyster shells could significantly improve the length (F = 12.248, P = 0.005), weight(F = 138.234, P &lt; 0.001), and survival rate (F = 15.248, P &lt; 0.001) of shrimp, while there were no significant differences in the length (F = -1.233, P = 0.267) and survival rate (F = -2.143, P = 0.076) between the high and low concentration groups. Additionally, oyster shell addition resulted in elevated phosphate levels (F = 74.92, P &lt; 0.001 in Day 70), diminished nitrite levels (F = 5.276, P = 0.031 in Day 56), and increased nitrate concentrations (F = 9.421, P = 0.006 in Day 70). Within the biofilms, the relative abundances of Ruegeria, Tenacibaculum, BD2- 11_terrestrial_group, and Kapabacteriales exhibited significant declines over time, whereas the relative abundance of Nitrospira demonstrated a marked increase, ultimately emerging as the predominant bacterium (Relative abundance 31.8%) in the biofilms during the latter stages of the experiment. Nitrospira also exhibited a notably higher relative abundance in the microbial community of the experimental water group relative to the control group (F = 2.265, P = 0.001).DiscussionThe biofilm provided conditions for the proliferation of Nitrospira, thereby accelerating the transformation of nitrite into nitrate in the aquaculture system, which subsequently improved the shrimp farming conditions. This research offers valuable insights for the application of oyster shells in shrimp farming and contributes to the theoretical underpinnings necessary for advancing our understanding of the mechanisms through which oyster shell biofilms enhance water quality and foster shrimp health.
Incidence and predictors of mortality among patients admitted to adult intensive care unit at public hospitals in Western Ethiopia: a retrospective cohort study
Authors: Kebede Fetene , Mosisa Getu , Yilma Mekdes 
Published: November 2024

IntroductionIn resource-constrained countries, the incidence of mortality among patients admitted to adult intensive care units is higher than that in developed countries, which has a physical, economic, and emotional impact on the lives of patients and their families. However, there is limited evidence on factors related to nursing care that can potentially contribute to predicting and reducing mortality rates in intensive care units. Therefore, this study aimed to assess the incidence of mortality and its predictors in patients admitted to an adult intensive care unit.MethodsA retrospective cohort study was conducted among 403 patients admitted to the adult intensive care unit from 1 January 2021 to 31 December 2021. The collected data were entered into Epi Data Manager v4.6.0.6 and exported to SPSS version 24 for analysis. Binary logistic regression was used to identify the predictors of mortality. Variables with a p-value less than 0.25 in bivariable logistic regression were selected for multivariable logistic regression. A p-value &lt;0.05 was used to indicate a significant association in multivariable analysis. Finally, the adjusted relative risk (RR) with 95% CI was calculated.ResultsA total of 403 patients were included in the analysis. The cumulative incidence of death was 40.9% (95% CI 36, 45.9%). Mortality was significantly associated with the need for mechanical ventilation (adjusted RR = 1.45; 95% CI: 1.04, 1.85), the Glasgow Coma Scale score &lt; 8 (adjusted RR, 3.52; 95% CI: 2.90, 4.05), presence of comorbidity (adjusted RR, 1.47; 95% CI: 1.09, 1.83), length of stay in ICU &lt; 24 h (adjusted RR, 1.84; 95% CI: 1.37, 2.04), oxygen saturation level, and Feeding, Analgesia, Sedation, Thrombosis prophylaxis, Head elevation, Ulcer prophylaxis, and Glucose control (FASTHUG) treatment received were significantly associated with mortality.ConclusionThe study found a high incidence proportion of death. The need for mechanical ventilation, length of stay, comorbidity, and the Glasgow Coma Scale score were significantly associated with mortality. Therefore, close monitoring and evaluation of patients are essential to improve treatment outcomes.
Poor treatment outcomes of acute exacerbations of chronic obstructive pulmonary disease and their associated factors among admitted patients in East Gojjam, 2023
Authors: Getnet Melaku Tadele , Afenigus Abebe Dilie , Gete Menberu , Emrie Ambaw Abebaw , Tsegaye Dejen 
Published: November 2024

BackgroundAcute exacerbation of chronic obstructive pulmonary disease (COPD) poses a significant public health challenge globally, resulting in considerable health and economic burden. To date, there has been insufficient research in Ethiopia regarding poor treatment outcomes associated with these acute exacerbations.ObjectiveThis study aims to assess the poor treatment outcomes of acute exacerbations of chronic obstructive pulmonary disease and identify the associated factors among admitted patients in East Gojjam in 2023.DesignAn institutional-based cross-sectional study design was employed.MethodsThe institutional-based cross-sectional study was conducted from 7 April 2023 to 7 May 2023, involving 384 participants selected through simple random sampling. Data were extracted from patient charts and registers. Data entry was performed using EpiData, and the analysis was conducted using IBM SPSS Statistics version 26 software. Binary logistic regression analysis was used to identify the association between dependent and independent variables. Variables with a p-value of &lt;0.25 in the bivariable logistic regression analysis were considered candidates for multivariable logistic regression. Variables with a p-value of &lt;0.05 were considered statistically significant.ResultsOut of a total of 346 patients, 99 (28.6%) (95% CI, 23.9–33.3) developed poor treatment outcomes following exacerbations of chronic obstructive pulmonary diseases. Poor treatment outcomes were significantly associated with the following variables: age 65 or older (AOR = 3.9; 95% CI: 1.57–9.71), presence of comorbidities (AOR = 2.6; 95% CI: 1.287–5.20), a hospital stay longer than 7 days (AOR = 3.9; 95% CI: 1.97–7.70), and low oxygen saturation (&lt;88%) (AOR = 9.0; 95% CI: 4.43–18.34).ConclusionApproximately one-third of the patients treated for acute exacerbations of chronic obstructive pulmonary disease at the Debre Markos Comprehensive Specialized Hospital experienced poor treatment outcomes. There is a significant association between poor treatment outcomes of acute exacerbation of chronic obstructive pulmonary disease and age ≥ 65 years, having comorbidities, prolonged hospital stay, and low oxygen saturation.
Unveiling the efficacy of paroxetine and gabapentin in ulcerative colitis patients in remission with co-existing IBS-like symptoms: a single-blinded randomized clinical trial
Authors: Safaei Farahnaz , Shahrokh Shabnam , Naderi Nosratollah , Rastegar Reyhaneh , Shamsi Alireza 
Published: November 2024

IntroductionThis clinical trial is designed to explore the efficacy of paroxetine and gabapentin in alleviating functional gastrointestinal symptoms, anxiety, depression, and quality of life in patients with ulcerative colitis during the remission stage.MethodsThe study enrolled 97 patients with ulcerative colitis in remission who had reported functional gastrointestinal symptoms. Patients were measured in terms of quality of life, anxiety, depression, and IBS severity. One group received paroxetine at a dosage of 20 mg/day, and the other group received gabapentin at a dosage of 100 mg/day in the first month and 300 mg/day in the second and third months. The patients were followed up for 3 months.ResultsAnxiety (p &lt; 0.001), depression (p = 0.012), and severity score levels (p = 0.045) among patients in the paroxetine group were significantly lower compared to the gabapentin group following the intervention. Paired evaluation in each treatment group revealed a significant reduction in the paroxetine group, while changes in the gabapentin group were not significant. Quality-of-life scores among patients in the paroxetine group were significantly higher compared to the gabapentin group following the intervention (p &lt; 0.001).ConclusionThe rate of improvement in gastrointestinal functional symptoms, anxiety, depression, and quality of life is significantly superior with paroxetine compared to gabapentin.Clinical trial registrationhttps://irct.behdasht.gov.ir/trial/69397, identifier RCT20220417054557N1.
Impact of the COVID-19 pandemic on surgical education and training programs in Latin America: a systematic review
Authors: Loza Hernandez Felipe , Ochoa Lantigua Pamela , Puga Rosero Vanesa , Jara Jimenez Sebastian , Carrera Cajamarca Mateo , Leon-Rojas Jose E. 
Published: November 2024

BackgroundThe COVID-19 pandemic posed challenges to surgical training, demanding a balance between theoretical and practical knowledge, especially in Latin American countries. Therefore, our aim was to characterize the challenges faced by surgical education in these countries.MethodsA systematic search was conducted on PubMed, Scopus, and the Virtual Health Library on March 23, 2022, yielding 2,838 articles. Articles were filtered by two independent reviewers focusing on the effect of the pandemic in surgical education.ResultsA total of 31 articles were selected; 54.83% of surgical programs reported a reduction in surgical involvement by trainees. First-year residents were the most affected, with some surgical residency programs forced to shift their residents to take care of COVID-19 patients; additionally, in 67.74% of cases, online courses and virtual simulation was implemented. Most of the residents had a positive opinion regarding virtual lectures but considered that their surgical skills were affected.ConclusionThe development of surgical skills was hindered by changes in surgery prioritization, techniques, and a decrease in caseload. The pandemic also caused a reliance on virtual formats for education and patient care. This shift created irregularities in training but increased opportunities for alternate activities.
Research focus and emerging trends of the gut microbiome and infant: a bibliometric analysis from 2004 to 2024
Authors: Yang Ru , Shi Zeyao , Li Yuan , Huang Xi , Li Yingxin , Li Xia , Chen Qiong , Hu Yanling , Li Xiaowen 
Published: November 2024

BackgroundOver the past two decades, gut microbiota has demonstrated unprecedented potential in human diseases and health. The gut microbiota in early life is crucial for later health outcomes. This study aims to reveal the knowledge collaboration network, research hotspots, and explore the emerging trends in the fields of infant and gut microbiome using bibliometric analysis.MethodWe searched the literature on infant and gut microbiome in the Web of Science Core Collection (WOSCC) database from 2004 to 2024. CiteSpace V (version: 6.3.R1) and VOSview (version: 1.6.20) were used to display the top authors, journals, institutions, countries, authors, keywords, co-cited articles, and potential trends.ResultsA total of 9,899 documents were retrieved from the Web of Science Core Collection. The United States, China, and Italy were the three most productive countries with 3,163, 1,510, and 660 publications. The University of California System was the most prolific institution (524 publications). Van Sinderen, Douwe from University College Cork of Ireland was the most impactful author. Many studies have focused on atopic dermatitis (AD), necrotizing enterocolitis (NEC), as well as the immune mechanisms and microbial treatments for these diseases, such as probiotic strains mixtures and human milk oligosaccharides (HMOs). The mother-to-infant microbiome transmission, chain fatty acids, and butyrate maybe the emerging trends.ConclusionThis study provided an overview of the knowledge structure of infant and gut microbiome, as well as a reference for future research.