bluuebunny/crossref_metadata_2025_split huggingface dataset:
Limites e avanços do Programa Minha Casa Minha Vida (PMCMV): o caso do Conjunto Habitacional Jardim Europa em Fazenda Rio Grande
Authors: Ribeiro Corina Alessandra Bezerra Carril , Bega Maria Tarcisa Silva 
Published: November 2018

Desde 2003, com a criação do Ministério das Cidades, o Brasil tem se destacado pela implantação de Políticas Públicas habitacionais como o Programa de Aceleração do Crescimento (PAC) criado em 2007 e o Programa Minha Casa Minha Vida (PMCMV), de 2009, que contaram com grande divulgação na mídia. Segundo o governo federal o PMCMV é a maior niciativa de acesso à casa própria já criada no Brasil (Ministério das Cidades, 2016, p.22). O PMCMV apresenta avanços significativos como Política Pública quanto ao acesso à moradia para milhares de famílias de baixa renda, entretanto, houve a ocorrência de erros na execução dos projetos; qualidade do material construtivo e localização dos conjuntos, os quais demonstraram a necessidade de aperfeiçoamento e incorporação de melhorias. A pesquisa indica que o PMCMV além do acesso à casa própria representa um primeiro passo para o exercício da cidadania, mas, necessita de aperfeiçoamento contínuo e de Políticas Públicas integradas. O problema da habitação vai além do morar, sendo necessário que sejam disponibilizados aos beneficiários os serviços e equipamentos públicos necessários, tais como transporte, escola, emprego, saúde, acesso a serviços e áreas de lazer para que as famílias morem de forma adequada. Palavras-chave: Programa Minha Casa Minha Vida; Fazenda Rio Grande;Conjunto Jardim Europa.
Adoption of Population-Level Statistical Methods Did Transform Psychological Science but For the Better: Commentary on Lamiell (2018)
Authors: Proctor Robert W. , Xiong Aiping 
Published: November 2018

Abstract
Lamiell presents a case that differential psychology (the study of individual differences) and experimental psychology should properly be classified as a form of demography (psychodemography) rather than psychology. He indicates that individual differences pertain to correlations in a population and maintains that mainstream psychology misinterprets such correlations as attributes of individuals. Lamiell also claims that because experimental psychology uses group designs, it too is demography, and he recommends that experimental psychology return to “genuinely appropriate” methods of deriving general laws from the study of individuals. We disagree with Lamiell’s assessment and classifications, and we emphasize that group experiments have yielded considerable knowledge about the nature of information processing in individuals.
Activisme autochtone et production audiovisuelle au Mato Grosso do Sul, Brésil
Authors: Castilho da Silva Marta 
Published: November 2018

Au Brésil, la population autochtone compte près de 900 000 personnes réparties en 305 groupes autochtones. La deuxième population autochtone la plus nombreuse se concentre dans l’État du Mato Grosso do Sul. Cet État est devenu un pôle de production agroalimentaire et de biocarburant à grande échelle, et sa population autochtone est à présent la plus menacée du pays. Dans cet article, basé sur son travail de terrain au Mato Grosso do Sul, l’auteure analyse comment les pratiques de l’audiovisuel s’inscrivent dans l’activisme autochtone. Cet activisme s’est développé à partir de 2008 pour prévenir la désintégration sociale des groupes autochtones et pour affirmer leur identité.
Two field studies on the effects of alcohol on eyewitness identification, confidence, and decision times
Authors: Sauerland Melanie , Broers Nick J. , van Oorsouw Kim 
Published: November 2018

SummaryIn two field studies, bar tenants (Ns = 86 and 190, respectively) were successively approached by confederates C1 and C2 on a night out. Confederate C3 then presented participants with a six‐person target‐absent or target‐present lineup concerning C1 or C2 (immediate test). Several days later, participants viewed a lineup regarding the confederate they had not attempted to identify earlier (C1/C2; delayed test). An immediate compared with a delayed, sober identification test did not increase the risk of a false identification decision. A blood alcohol concentration of 0.06–0.07% best discriminated accurate from inaccurate decisions. Choosers with a blood alcohol concentration ≤ 0.06% showed excellent calibration and little overconfidence, and their confidence was a strong indicator of accuracy (i.e., good resolution). Choosers with a higher intoxication level displayed poor calibration and strong overconfidence. Nonchoosers were generally poorly calibrated. Combined analyses showed a negative effect of intoxication on one's ability to discriminate the target from nontargets.
Intermetallic Electride Catalyst as a Platform for Ammonia Synthesis
Authors: Wu Jiazhen , Li Jiang , Gong Yutong , Kitano Masaaki , Inoshita Takeshi , Hosono Hideo 
Published: November 2018

AbstractElectrides loaded with transition‐metal (TM) nanoparticles have recently attracted attention as emerging materials for catalytic NH3 synthesis. However, they suffer from disadvantages associated with the growth and aggregation of nanoparticles. TM‐containing intermetallic electrides appear to be promising catalysts with the advantages of both electrides and transition metals in a single phase. LaRuSi is reported here to be an intermetallic electride with superior activity for NH3 synthesis, and direct evidence is provided supporting its electride‐character‐induced catalytic performance. The discussion is made mainly based on the contrasting synthesis rates over the isostructural compounds LaRuSi, CaRuSi, and LaRu2Si2, and the N2 isotope‐exchange reactions over these compounds. Lattice hydride ions, which can reversibly exchange with anionic electrons, are shown to be indispensable in the promotion of NHx formation. The mechanism derived from the present findings provides new guidelines for NH3 synthesis.
Jugendherberge Bayreuth: konzeptionell innovativ und tragstrukturell hybrid
Authors: Engelsmann Stephan , Peters Stefan , Dengler Christoph , Streib Johannes 
Published: November 2018

AbstractDer Neubau der Jugendherberge Bayreuth ist ein Vorzeigeprojekt der Modernisierungs‐ und Erneuerungsstrategie des Deutschen Jugendherbergswerks. Er ist Bestandteil eines Gesamtkonzepts zur Entwicklung von architektonisch und sozial zeitgemäßen Jugendgästehäusern, das in Form von prototypischen Bauwerken umgesetzt werden und Ausgangspunkt für eine neue Generation von Jugendherbergsgebäuden sein soll. Ziel des Konzepts ist eine funktional und gestalterisch anspruchsvolle Neuinterpretation der Bauaufgabe Jugendherberge. Insbesondere gehören zu dieser Strategie innovative räumliche Konfigurationen, Nachhaltigkeit in funktionaler, baulicher und energetischer Hinsicht sowie die Verbindung von kulturellen und sportlichen Angeboten. Das Tragwerk des Gebäudes ist im Sinne dieser übergeordneten Planungsziele in einer Hybridbauweise aus Holz und Stahlbeton gebaut. In tragwerksplanerischer Hinsicht bemerkenswert sind insbesondere eine geometrisch komplexe, doppelt gekrümmte Dachkonstruktion in Holzbauweise und der Einsatz von parametrischen Planungswerkzeugen.
Predicting Genes in Single Genomes with AUGUSTUS
Authors: Hoff Katharina J. , Stanke Mario 
Published: November 2018

AbstractAUGUSTUS is a tool for finding protein‐coding genes and their exon‐intron structure in genomic sequences. It does not necessarily require additional experimental input, as it can be applied in so‐called ab initio mode. However, extrinsic evidence from various sources such as transcriptome sequencing or the annotations of closely related genomes can be integrated in order to improve the accuracy and completeness of the annotation. AUGUSTUS can be applied to single genomes, or simultaneously to several aligned genomes. Here, we describe steps required for training AUGUSTUS for the annotation of individual genomes and the steps to do the actual structural annotation. Further, we describe the generation and integration of evidence from various sources of extrinsic evidence. © 2018 by John Wiley & Sons, Inc.
USP14 promotes K63‐linked RIG‐I deubiquitination and suppresses antiviral immune responses
Authors: Li Hongrui , Zhao Zizhao , Ling Jing , Pan Linhui , Zhao Xibao , Zhu Huihui , Yu Juan , Xie Bin , Shen Jianzhong , Chen Weilin 
Published: November 2018

AbstractRetinoic acid‐inducible gene I (RIG‐I) is a critical RNA virus sensor that initiates antiviral immune response through K63‐linked ubiquitination. In this study, we demonstrated USP14, a deubiquitinating enzyme, as a negative regulator in antiviral responses by directly deubiquitinating K63‐linked RIG‐I. USP14 knockdown significantly enhanced RIG‐I‐triggered type I IFN signaling and inhibited vesicular stomatitis virus (VSV) replication both in mouse peritoneal macrophages and THP1 cells. USP14 overexpression in HeLa cells attenuated RIG‐I‐triggered IFN‐β expression and promoted VSV replication. Besides, USP14‐specific inhibitor, IU1, increased RIG‐I‐mediated type I IFN production and antiviral responses in vitro and in vivo. In addition, USP14 could interact with RIG‐I and remove RIG‐I K63‐linked polyubiquitination chains. This article is the first to report that USP14 acts as a negative regulator in antiviral response through deubiquitinating K63‐linked RIG‐I. These findings provide insights into a potential new therapy targeting USP14 for RNA virus‐related diseases.
Diagnosis, anatomy, and electromyography profiles of 73 nonrecurrent laryngeal nerves
Authors: Wang Tie , Dionigi Gianlorenzo , Zhang Daqi , Bian Xuehai , Zhou Le , Fu Yantao , Zhang Guang , Liu Xiaoli , Sun Hui 
Published: November 2018

AbstractBackgroundThe purpose of this work was to compare methods of detecting nonrecurrent laryngeal nerves (NRLNs).MethodsSpecificity and sensitivity were compared in three NRLN detection methods: CT, electromyography (EMG), and A‐B point comparison.ResultsA total of 73 intraoperative pictures and 36 CT details of NRLNs are presented. Incidence of NRLN was 0.39%. Type I NRLN accounted for 50.7%, type IIA 45.2%, type IIB 4.1%. The NRLN median latency was 2.13 ms vs 3.00 ms median in an RLN control group (P < .001). When the threshold was set to 2.5 ms, EMG latency detection had 96.7% sensitivity and 91.6% specificity for detecting NRLN, and the A‐B point comparison algrithm had 97.3% sensitivity and 92.5% specificity. Combining EMG latency detection with A‐B point comparison achieved 100% sensitivity and specificity for detecting NRLN.ConclusionThis is the largest series of NRLN presented in the literature. Latency shorter than 2.50 ms combined with the A‐B point comparison method is the ideal algorithm procedure for early NRLN identification.
Lung inflammation and disease: A perspective on microbial homeostasis and metabolism
Authors: Mendez Roberto , Banerjee Sulagna , Bhattacharya Sanjoy K. , Banerjee Santanu 
Published: November 2018

AbstractIt is now well appreciated that the human microbiome plays a significant role in a number of processes in the body, significantly affecting its metabolic, inflammatory, and immune homeostasis. Recent research has revealed that almost every mucosal surface in the human body is associated with a resident commensal microbiome of its own. While the gut microbiome and its role in regulation of host metabolism along with its alteration in a disease state has been well studied, there is a lacuna in understanding the resident microbiota of other mucosal surfaces. Among these, the scientific information on the role of lung microbiota in pulmonary diseases is currently severely limited. Historically, lungs have been considered to be sterile and lung diseases have only been studied in the context of bacterial pathogenesis. Recently however, studies have revealed a resilient microbiome in the upper and lower respiratory tracts and there is increased evidence on its central role in respiratory diseases. Knowledge of lung microbiome and its metabolic fallout (local and systemic) is still in its nascent stages and attracting immense interest in recent times. In this review, we will provide a perspective on lung‐associated metabolic disorders defined for lung diseases (e.g., chronic obstructive pulmonary disease, asthma, and respiratory depression due to infection) and correlate it with lung microbial perturbation. Such perturbations may be due to altered biochemical or metabolic stress as well. Finally, we will draw evidence from microbiome and classical microbiology literature to demonstrate how specific lung morbidities associate with specific metabolic characteristics of the disease, and with the role of microbiome in this context. © 2018 IUBMB Life, 71(1):152–165, 2019
Time to Full Enteral Feeding for Very Low‐Birth‐Weight Infants Varies Markedly Among Hospitals Worldwide But May Not Be Associated With Incidence of Necrotizing Enterocolitis: The NEOMUNE‐NeoNutriNet Cohort Study
Authors: de Waard Marita , Li Yanqi , Zhu Yanna , Ayede Adejumoke I. , Berrington Janet , Bloomfield Frank H. , Busari Olubunmi O. , Cormack Barbara E. , Embleton Nicholas D. , van Goudoever Johannes B. , Greisen Gorm , He Zhongqian , Huang Yan , Li Xiaodong , Lin Hung‐Chih , Mei Jiaping , Meier Paula P. , Nie Chuan , Patel Aloka L. , Ritz Christian , Sangild Per T. , Skeath Thomas , Simmer Karen , Tongo Olukemi O. , Uhlenfeldt Signe S. , Ye Sufen , Ye Xuqiang , Zhang Chunyi , Zhou Ping 
Published: November 2018

AbstractBackgroundTransition to enteral feeding is difficult for very low‐birth‐weight (VLBW; ≤1500 g) infants, and optimal nutrition is important for clinical outcomes.MethodData on feeding practices and short‐term clinical outcomes (growth, necrotizing enterocolitis [NEC], mortality) in VLBW infants were collected from 13 neonatal intensive care units (NICUs) in 5 continents (n = 2947). Specifically, 5 NICUs in Guangdong province in China (GD), mainly using formula feeding and slow feeding advancement (n = 1366), were compared with the remaining NICUs (non‐GD, n = 1581, Oceania, Europe, United States, Taiwan, Africa) using mainly human milk with faster advancement rates.ResultsAcross NICUs, large differences were observed for time to reach full enteral feeding (TFF; 8–33 days), weight gain (5.0–14.6 g/kg/day), ∆z‐scores (−0.54 to −1.64), incidence of NEC (1%–13%), and mortality (1%–18%). Adjusted for gestational age, GD units had longer TFF (26 vs 11 days), lower weight gain (8.7 vs 10.9 g/kg/day), and more days on antibiotics (17 vs 11 days; all P < .001) than non‐GD units, but NEC incidence and mortality were similar.ConclusionFeeding practices for VLBW infants vary markedly around the world. Use of formula and long TFF in South China was associated with more use of antibiotics and slower weight gain, but apparently not with more NEC or higher mortality. Both infant‐ and hospital‐related factors influence feeding practices for preterm infants. Multicenter, randomized controlled trials are required to identify the optimal feeding strategy during the first weeks of life.
Architecture conformance analysis using model‐based testing: A case study approach
Authors: Uzun Burak , Tekinerdogan Bedir 
Published: November 2018

SummaryContext: The architectural drift problem defines the discrepancy between the architecture description and the code. Deviations of the code from the architecture can occur if architectural constraints as defined in the architectural models are not implemented in the code. For large‐scale systems, manually checking the consistency of the architecture with the code is not trivial and cumbersome.Objective: The overall objective of this paper is to propose and analyze the effectiveness and practicality of an architecture conformance analysis approach using model‐based testing (ACAMBT) approach for checking the consistency between architectural models and the code. Hereby, we consider the case whereby the architecture is assumed correct, and the code needs to align with the architecture.Method: We propose a model‐based testing that uses architectural views to automatically derive test cases for checking the architectural constraints in the code. We have evaluated the approach and the corresponding toolset for a real industrial case study using a systematic case study protocol. Further, we have adopted exhaustive fault‐injection techniques to detect the constraint violations.Results: The evaluation of the approach on real code showed that deviations with the architectural constraints could be easily detected in the code.Conclusion: We can conclude that ACAMBT is effective for identifying inconsistencies between the architecture views and the code for the defined view constraints. Our survey study with practitioners showed that adopting the ACAMBT approach is practical and easy to use. The approach as such can be considered as a complimentary tool to the existing testing and reflexion modeling approaches.
Age‐related changes in Ki‐67 and DCX expression in the BALB/ c mouse (Mus Musculus) brain
Authors: Nkomozepi Pilani , Mazengenya Pedzisai , Ihunwo Amadi O. 
Published: November 2018

AbstractSeveral studies have identified age as one of the strongest regulators of neurogenesis in the mammalian brain. However, previous age‐related studies focused mainly on changes in neurogenesis during different stages of adulthood and did not describe changes in neurogenesis through the different life history stages of the animal. The aim of this study was therefore to determine time course changes in neurogenesis in the male BALB/c mouse brain at postnatal ages 1 week to 12 weeks, spanning juvenile, sub adult and adult life history stages. To achieve this, Ki‐67 and DCX immunohistochemistry was used to assess changes in cell proliferation and neuronal incorporation respectively. Ki‐67 expression was mainly observed in the olfactory bulb, rostral migratory stream, sub ventricular zone of lateral ventricle and the sub granular zone of the dentate gyrus. In addition, fewer Ki‐67 positive cells were also observed in the neocortex, cerebellum and tectum. DCX was expressed in similar regions as Ki‐67 except for the cerebellum and tectum. Expression of both Ki‐67 and DCX sharply decreased with advancing age or life history stages in the sub ventricular zone, rostral migratory stream and sub granular zone of the BALB/c mouse brain. Neurogenesis therefore persists throughout all life history stages in the BALB/c mouse brain although it decreases with age.
HOW FUNCTIONAL DATA CAN ENHANCE THE ESTIMATION OF HEALTH EXPECTANCY: THE CASE OF DISABLED SPANISH POPULATION
Authors: Albarrán Irene , Alonso-González Pablo J. , Arribas-Gil Ana , Grané Aurea 
Published: November 2018

AbstractThe aging of population is perhaps the most important problem that developed countries must face in the near future. Dependency can be seen as a consequence of the process of gradual aging. In a health context, this contingency is defined as a lack of autonomy in performing basic activities of daily living that requires the care of another person or significant help. In Europe in general and in Spain in particular, this phenomena represents a problem with economic, political, social and demographic implications. The prevalence of dependency in the population, as well as its intensity and evolution over the course of a person’s life are issues of greatest importance that should be addressed. The aim of this work is the estimation of life expectancy free of dependency (LEFD) based on functional trajectories to enhance the regular estimation of health expectancy. Using information from the Spanish survey EDAD 2008, we estimate the number of years spent free of dependency for disabled people according to gender, dependency degree (moderate, severe, major) and the earlier or later onset of dependency compared to a central trend. The main findings are as follows: first, we show evidence that to estimate LEFD ignoring the information provided by the functional trajectories may lead to non-representative LEFD estimates; second, in general, dependency-free life expectancy is higher for women than for men. However, its intensity is higher in women with later onset on dependency; Third, the loss of autonomy is higher (and more abrupt) in men than in women. Finally, the diversity of patterns observed at later onset of dependency tends to a dependency extreme-pattern in both genders.
Evaluating Different Techniques for Constraining Lower Atmospheric Variability in an Upper Atmosphere General Circulation Model: A Case Study During the 2010 Sudden Stratospheric Warming
Authors: Jones McArthur , Drob Douglas P. , Siskind David E. , McCormack John P. , Maute Astrid , McDonald Sarah E. , Dymond Kenneth F. 
Published: November 2018

AbstractWe analyze the effects specified dynamics (SD) and 4D Tendency nudging have on accurately reproducing the middle and upper atmospheric variability induced by the 2010 sudden stratospheric warming (SSW) event in the National Center for Atmospheric Research thermosphere‐ionosphere‐mesosphere‐electrodynamics general circulation model (TIME‐GCM). TIME‐GCM numerical experiments were performed using constrained middle atmospheric winds and temperatures from a high‐altitude version of the Navy Global Environmental Model to compare the previously implemented SD scheme, with the newly implemented 4D Tendency scheme. Model comparisons focused on zonal mean winds, composition, planetary waves, and tides in the thermosphere‐ionosphere system. Through 4D Tendency nudging we reveal that coupling coefficients of the one‐way SD coupling approach between the TIME‐GCM and observed SSW conditions were too strong. Prior implementations produced unusually strong vertical shears in the zonal mean winds in the mesosphere and lower thermosphere (MLT), where the model is free running. Differences in zonal mean MLT winds between SD and 4D Tendency nudging simulations resulted in migrating diurnal (DW1) and semidiurnal (SW2) tidal amplitude differences at lower thermospheric altitudes. The consequences of simulating different MLT dynamics using SD and 4D Tendency nudging in the overlaying ionosphere are reported and validated using electron density data from the Constellation Observing System for Meteorology, Ionosphere, and Climate satellites. Although we demonstrate that SD and 4D Tendency nudging techniques are approximately equivalent, results presented herein establish that 4D Tendency nudging has the added potential to identify physical model parameters that contribute to data‐model differences during the 2010 SSW.
A new look at effective interactions between microgel particles
Authors: Bergman Maxime J. , Gnan Nicoletta , Obiols-Rabasa Marc , Meijer Janne-Mieke , Rovigatti Lorenzo , Zaccarelli Emanuela , Schurtenberger Peter 
Published: November 2018

AbstractThermoresponsive microgels find widespread use as colloidal model systems, because their temperature-dependent size allows facile tuning of their volume fraction in situ. However, an interaction potential unifying their behavior across the entire phase diagram is sorely lacking. Here we investigate microgel suspensions in the fluid regime at different volume fractions and temperatures, and in the presence of another population of small microgels, combining confocal microscopy experiments and numerical simulations. We find that effective interactions between microgels are clearly temperature dependent. In addition, microgel mixtures possess an enhanced stability compared to hard colloid mixtures - a property not predicted by a simple Hertzian model. Based on numerical calculations we propose a multi-Hertzian model, which reproduces the experimental behavior for all studied conditions. Our findings highlight that effective interactions between microgels are much more complex than usually assumed, displaying a crucial dependence on temperature and on the internal core-corona architecture of the particles.