bluuebunny/crossref_metadata_2025_split huggingface dataset:
Methane Activation by (n=0, 1, 2; m= 1, 2): Reactivity Parameters, Electronic Properties and Binding Energy Analysis
Authors: Silva Telles Cardoso , dos Santos Pires Maíra , de Castro Alexandre Alves , Lacerda Lívia Clara Tavares , Rocha Marcus Vinícius Juliaci , Ramalho Teodorico Castro 
Published: July 2019

AbstractThe need for renewal and more efficient energy resources has led to a great interest in carrying out studies aiming to find novel sources of energy, which are able to supply the growing global demand, and providing an eco‐friendly usage of natural resources. In this context, the usage of methane stands out as a promising energetic alternative, mostly due to vast reserves, low cost and less polluting fuel. Theoretical studies with B3LYP, CCSD (t) and ZORA−B3LYP methods were used to look into the catalytic properties of (n= 0, 1, 2 and m=1, 2) in the methane C−H bond activation. According to the EDA results, the studied species presented two stabilizing factors for the global interaction energy, being the electrostatic ΔEelstatand orbital ΔEorbinteractions. The HOMO and LUMO orbitals were also evaluated based on the molecular orbital diagrams for the monoxides and dioxides series. Regarding the oxidative insertion mechanism, the results demonstrate that the initial interaction between oxide and methane is of great relevance in its activation process, in which EBondingis benefited by the increasingly charge on the central metal. The high electron density regarding the oxides is meaningful for the reaction kinetics and the oxo ligands influence the thermodynamics of the reaction, becoming the DHA mechanism exergonic. Regarding the OHM mechanism, better kinetic conditions are found for CoO2++and better thermodynamics for doubly charged cobalt monoxides and dioxides.
Protective effects of hepatocyte growth factor gene overexpression against hydrogen peroxide‐induced apoptosis in mesenchymal stem cells
Authors: Choi Yong Jun , Lee Chang Min , Lee Jeong Hyun , Park See‐Hyoung , Nam Myeong Jin 
Published: July 2019

AbstractHepatocyte growth factor (HGF) has recently been reported to exhibit antioxidant and antiapoptotic effects. Therefore, we investigated the effect of overexpression of HGF gene in H2O2‐treated mesenchymal stem cells (MSCs). HGF‐overexpression increased the cell viability from 50% to 84%, decreased the population of apoptotic cells from 20% to 16%, and decreased the intracellular reactive oxygen species (ROS) levels from 127% to 100% in cells treated with H2O2. HGF suppression decreased the cell viability from 58% to 36%, increased the population of apoptotic cells from 23 to 81%, and increased the intracellular ROS levels from 181% to 240% in cells exposed to H2O2. HGF‐overexpression also reduced the expression levels of proapoptotic proteins in MSCs treated with H2O2. Phosphorylation of extracellular signal‐regulated kinases, c‐Jun amino‐terminal kinases, and p38, which was induced by H2O2, decreased in MSCs overexpressing the HGF gene. Taken together, our results suggest that HGF has a protective effect on H2O2‐induced apoptosis in MSCs.
An inelastic bound on chaos
Authors: Turiaci Gustavo J. 
Published: July 2019

AbstractWe study a generalization of the chaos bound that applies to out-of-time-ordered correlators between four different operators. We prove this bound under the same assumptions that apply for the usual chaos bound and extend it to non-hermitian operators. In a holographic theory, these correlators are controlled by inelastic scattering in the bulk and we comment on implications. In particular, for holographic theories the bound together with the equivalence principle suggests that gravity is the highest spin force, and the strongest one with that spin.
Effect of temperature on methane oxidation and community composition in landfill cover soil
Authors: Reddy Krishna R , Rai Raksha K , Green Stefan J , Chetri Jyoti K 
Published: July 2019

Abstract
Municipal solid waste (MSW) landfills are the third largest anthropogenic source of methane (CH4) emissions in the United States. The majority of CH4 generated in landfills is converted to carbon dioxide (CO2) by CH4-oxidizing bacteria (MOB) present in the landfill cover soil, whose activity is controlled by various environmental factors including temperature. As landfill temperature can fluctuate substantially seasonally, rates of CH4 oxidation can also vary, and this could lead to incomplete oxidation. This study aims at analyzing the effect of temperature on CH4 oxidation potential and microbial community structure of methanotrophs in laboratory-based studies of landfill cover soil and cultivated consortia. Soil and enrichment cultures were incubated at temperatures ranging from 6 to 70 °C, and rates of CH4 oxidation were measured, and the microbial community structure was analyzed using 16S rRNA gene amplicon sequencing and shotgun metagenome sequencing. CH4 oxidation occurred at temperatures from 6 to 50 °C in soil microcosm tests, and 6–40 °C in enrichment culture batch tests; maximum rates of oxidation were obtained at 30 °C. A corresponding shift in the soil microbiota was observed, with a transition from putative psychrophilic to thermophilic methanotrophs with increasing incubation temperature. A strong shift in methanotrophic community structure was observed above 30 °C. At temperatures up to 30 °C, methanotrophs from the genus Methylobacter were dominant in soils and enrichment cultures; at a temperature of 40 °C, putative thermophilic methanotrophs from the genus Methylocaldum become dominant. Maximum rate measurements of nearly 195 μg CH4 g−1 day−1 were observed in soil incubations, while observed maximum rates in enrichments were significantly lower, likely as a result of diffusion limitations. This study demonstrates that temperature is a critical factor affecting rates of landfill soil CH4 oxidation in vitro and that changing rates of CH4 oxidation are in part driven by changes in methylotroph community structure.
Customer reactions to a webshop’s service quality
Authors: Hackl Franz , Winter-Ebmer Rudolf 
Published: July 2019

Abstract
E-commerce has become an integral part of the world’s economy. In this study we investigate the impact of service quality in e-tailing on site visits and consumer demand. Such an analysis is important given the almost Bertrand-like competitive structure. Our analysis is based on a large representative data set obtained from a price comparison site covering essentially the complete Austrian e-tailing market. Customer evaluations for a broad range of 15 different service characteristics are condensed using factor analysis. Negative binomial regression analysis is used to measure the impact of service quality dimensions on referral requests to online shops for different product categories. Our results show that the most important service quality aspects are those related to the ordering process and the firm’s website performance.
Lyapunov Spectrum of Nonautonomous Linear Young Differential Equations
Authors: Cong Nguyen Dinh , Duc Luu Hoang , Hong Phan Thanh 
Published: July 2019

Abstract
We show that a linear Young differential equation generates a topological two-parameter flow, thus the notions of Lyapunov exponents and Lyapunov spectrum are well-defined. The spectrum can be computed using the discretized flow and is independent of the driving path for triangular systems which are regular in the sense of Lyapunov. In the stochastic setting, the system generates a stochastic two-parameter flow which satisfies the integrability condition, hence the Lyapunov exponents are random variables of finite moments. Finally, we prove a Millionshchikov theorem stating that almost all, in a sense of an invariant measure, linear nonautonomous Young differential equations are Lyapunov regular.
Factors Affecting Discharge Disposition after Primary Simultaneous Bilateral Joint Arthroplasty
Authors: Edwards Danielle , Anderson Allison , Pleus Michael R. , Smith Jerome B. , Nguyen Joseph T. 
Published: July 2019

Background Predicting discharge destination following total joint arthroplasty (TJA) is important, as discharge destination has major implications for post-operative costs, clinical outcomes, and readmissions. Few studies have looked at factors affecting discharge destination for patients following primary simultaneous bilateral total joint arthroplasty. Questions/Purposes The purpose of this study was to describe clinical and social factors that relate to a discharge to home versus rehabilitation facility (RF) for patients after primary simultaneous bilateral total hip arthroplasty (PSBTHA) or primary simultaneous bilateral total knee arthroplasty (PSBTKA). Methods The inclusion criteria for this retrospective cohort study were all patients after PSBTHA or PSBTKA at a metropolitan orthopedic specialty hospital between February 1, 2016, and March 31, 2018. Exclusion criteria were revisions, differing weight-bearing status, bed-rest orders, and non-standard hip precautions. Social and clinical demographic data were collected. Multiple regression analysis was conducted to determine which factors related most to discharge plan. Results Of 253 PSBTHA patients, 153 were discharged home and 100 to an RF. Regression analysis found a posterolateral approach to be the only significant factor associated with an RF discharge. Of 619 PSBTKA patients, 136 were discharged home and 483 to RF. Increased body mass index and older age increased the likelihood of discharge to an RF. Patients with an adductor-only nerve block were more likely to be sent to RF. Conclusion These findings shed light on the variables that contribute to discharge destination after PSBTHA and PSBTKA. Such information allows for safe pre-operative discharge planning and assists with discharge to the appropriate level of patient care. Future studies might investigate the effect of surgeon experience, surgical technique, and pre-operative discussion with a physical therapist on the discharge disposition of patients undergoing bilateral total joint arthroplasty.
Trade, transboundary impacts and the implementation of SDG 12
Authors: Amos Rob , Lydgate Emily 
Published: July 2019

Abstract
The 2015 Sustainable Development Goals (SDGs) were developed to ‘transform our world’. Yet critics argue that the concept of sustainable development serves to maintain an unsustainable status quo, or provide a positive gloss on a terminal conflict between its ‘pillars’: environmental protection, economic growth and social welfare. In this article, we examine this tension with respect to the implementation of SDG 12 in the European Union. SDG 12 calls for responsible consumption and production, which necessitates reconciling, or ‘decoupling’, economic growth and environmental degradation: the core of sustainable development. Initial examination reveals that the largest implementation gap is among high-consuming countries, including those of the EU, the focus of our article, who are failing to account for transboundary impacts of products consumed domestically. This shortcoming, facilitated by the flexibility of the SDG ‘global target, national action’ approach, undermines the achievement of other environmental SDGs relating to biodiversity and climate, among others. Yet, as compared to other EU approaches to addressing transboundary environmental harm from trade in existing Free Trade Agreements (FTAs) and Multilateral Environmental Agreements (MEAs), which we examine, the global focus and breadth of SDG 12 offers transformative potential. Ultimately, even if the three pillars of sustainable development are not ‘rebalanced’ toward environmental conservation, they can provide a construct for examining interactions and trade-offs between goals. Simply taking account of transboundary consumption, as SDG 12 indicators call for, would encourage more effective cooperation to help producing countries address environmental problems that result from production for export through impact assessment and enforcement.
Utility of serum ferritin and soluble interleukin-2 receptor as markers of disease activity in childhood systemic lupus erythematosus
Authors: Almutairi Nora , Aljaser Alwaleed , Almutairi Abdulaziz , Alshaikh Manal , Eldali Abdelmoneim , Al-Mayouf Sulaiman M. 
Published: July 2019

Objective:
To assess the usefulness of serum ferritin and soluble interleukin-2 receptor (sIL-2r) levels as markers of disease activity in childhood systemic lupus erythematosus (cSLE) and their role in screen for subclinical macrophage activation syndrome (MAS).

Patients and methods:
This is a cross-sectional analysis of prospectively collected data. Consecutive children who met the Systemic Lupus International Collaborating Clinics (SLICC) criteria were enrolled between June 2015 and June 2017. All patients interviewed and assessed for disease activity using SLE disease activity index (SLEDAI). Biochemical and serological tests including markers of disease activity and MAS were measured by standard laboratory procedure.

Results:
A total of 31 (25 female; 6 male) consecutive cSLE patients with a mean age of 10.6 (±3.2) years were included. The most frequent manifestations were mucocutaneous and musculoskeletal (84%) followed by hematological (64.5%) then renal involvement (58%). Twenty-two patients had active disease (SLEDAI ≥ 4), with a mean of 9.8. Mean serum ferritin and sIL-2r were 555 (±1860) and 2789 (±1299) respectively. Both correlated significantly with leucocyte, platelet count, transferrin, C3 and SLEDAI
(p <
0.05). Additionally, sIL-2r had positive correlation with ANA, ds-DNA and C4. Both ferritin and sIL-2r had weak correlation with ESR, but no correlation with CRP. Twelve patients had a recent infection. However, they were comparable to patients without infection with regard to all clinical and laboratory features. Three patients had MAS proved by bone marrow aspiration.

Conclusion:
Measurement of serum ferritin and sIL-2r might help in assessing disease activity of cSLE. Both might be good screening markers for MAS in cSLE. A larger prospective study is required to allow more definitive conclusions.
Bone Mineral Density in Transgender Individuals After Gonadectomy and Long-Term Gender-Affirming Hormonal Treatment
Authors: Dobrolińska Magdalena , van der Tuuk Karin , Vink Patti , van den Berg Marjan , Schuringa Anke , Monroy-Gonzalez Andrea G. , García David Vállez , Schultz Willibrord C.M. Weijmar , Slart Riemer H.J.A. 
Published: July 2019

ABSTRACT

Introduction
Establishing the influence of long-term, gender-affirming hormonal treatment (HT) on bone mineral density (BMD) in transgender individuals is important to improve the therapeutic guidelines for these individuals.

Aim
To examine the effect of long-term HT and gonadectomy on BMD in transgender individuals.

Methods
68 transwomen and 43 transmen treated with HT who had undergone gonadectomy participated in this study. Dual-energy x-ray absorptiometry (DXA) scans were performed to measure BMD at the lumbar spine and total hip. Laboratory values related to sex hormones were collected within 3 months of performing the DXA scan and analyzed.

Main Outcome Measure
BMD and levels of sex hormones in transwomen and transmen.

Results
In transwomen, the mean BMD values at the lumbar spine and total hip at the first DXA scan were, respectively, 0.99 ± 0.15 g/cm2 (n = 68) and 0.94 ± 0.28 g/cm2 (n = 65). In transmen, the mean BMD values at the lumbar spine and total hip at the first DXA scan were, respectively, 1.08 ± 0.16 g/cm2 (n = 43) and 1.01 ± 0.18 g/cm2 (n = 43). A significant decrease in total hip BMD was found in both transwomen and transmen after 15 years of HT compared with 10 years of HT (P = .02).

Conclusion
In both transwomen and transmen, a decrease was observed in total hip bone mineral density after 15 years of HT compared to the first 10 years of HT.
Clinical impact of an antimicrobial stewardship program on high-risk pediatric patients
Authors: Goldman Jennifer L. , Newland Jason G. , Price Michael , Yu Diana , Lee Brian R. 
Published: July 2019

AbstractObjective:To evaluate the clinical impact of an antimicrobial stewardship program (ASP) on high-risk pediatric patients.Design:Retrospective cohort study.Setting:Free-standing pediatric hospital.Patients:This study included patients who received an ASP review between March 3, 2008, and March 2, 2017, and were considered high-risk, including patients receiving care by the neonatal intensive care (NICU), hematology/oncology (H/O), or pediatric intensive care (PICU) medical teams.Methods:The ASP recommendations included stopping antibiotics; modifying antibiotic type, dose, or duration; or obtaining an infectious diseases consultation. The outcomes evaluated in all high-risk patients with ASP recommendations were (1) hospital-acquired Clostridium difficile infection, (2) mortality, and (3) 30-day readmission. Subanalyses were conducted to evaluate hospital length of stay (LOS) and tracheitis treatment failure. Multivariable generalized linear models were performed to examine the relationship between ASP recommendations and each outcome after adjusting for clinical service and indication for treatment.Results:The ASP made 2,088 recommendations, and 50% of these recommendations were to stop antibiotics. Recommendation agreement occurred in 70% of these cases. Agreement with an ASP recommendation was not associated with higher odds of mortality or hospital readmission. Patients with a single ASP review and agreed upon recommendation had a shorter median LOS (10.2 days vs 13.2 days; P < .05). The ASP recommendations were not associated with high rates of tracheitis treatment failure.Conclusions:ASP recommendations do not result in worse clinical outcomes among high-risk pediatric patients. Most ASP recommendations are to stop or to narrow antimicrobial therapy. Further work is needed to enhance stewardship efforts in high-risk pediatric patients.
The response of glyphosate-resistant and glyphosate-susceptible biotypes of junglerice (Echinochloa colona) to mungbean interference
Authors: Mutti Navneet Kaur , Mahajan Gulshan , Jha Prashant , Chauhan Bhagirath S. 
Published: July 2019

AbstractGlyphosate-resistant junglerice [Echinochloa colona(L.) Link] is a problematic weed in mungbean [Vigna radiata(L.) R. Wilczek] crops in Australia. Due to limited herbicide options in mungbean, there is an increased interest in developing integrated management strategies for the sustainable control ofE. colona. Pot experiments were conducted in a screenhouse in 2017 and 2018 by growingE. colonaplants (glyphosate-resistant [GR] and glyphosate-susceptible [GS] biotypes) alone (1 plant pot−1) and in competition with 4 and 8 mungbean plants pot−1. Both biotypes were developed from a single population using the clone method. The growth and seed production of both GR and GS biotypes were similar in response to mungbean competition. Averaged over biotypes, there was a reduction in the growth and seed production ofE. colonaas crop plants increased. Compared with the weed plants grown alone, crop interference reducedE. colonaheight by 17% to 19%, tiller numbers by 69% to 82%, total shoot biomass by 85% to 91%, and inflorescence numbers by 74% to 91%. WhenE. colonawas grown with 8 mungbean plants pot−1, leaf weight ratio increased by 42% compared with plants grown alone. Compared with weed plants grown alone, mungbean interference (4 and 8 plants pot−1) reduced weed seed production by 85% to 95%. These reductions were similar for both biotypes (GR and GS), suggesting that there was no fitness penalty associated with resistance. The results of this study suggest that mungbean interference can reduceE. colonagrowth and seed production, but it should not be considered as a stand-alone strategy to manageE. colonaand similar species in mungbean. These results also highlight the need for integrating crop competition with other management strategies to achieve complete and sustainable management of this weed.
Changes in the Thickness and Circulation of Multiyear Ice in the Beaufort Gyre Determined From Pseudo‐Lagrangian Methods from 2003–2015
Authors: Mahoney Andrew R. , Hutchings Jennifer K. , Eicken Hajo , Haas Christian 
Published: July 2019

AbstractWe combine Eulerian ice draft observations from moored ice‐profiling sonars with buoy‐ and satellite‐derived ice drift data to obtain Lagrangian observations of changes in the thickness distribution of sea ice circulating the Beaufort Sea. We examine repeat measurements of ice draft by identifying events where buoys or pseudobuoys made repeat overpasses within 30 km of ice‐profiling sonar‐equipped Beaufort Gyre Exploration Project moorings. Comparison of ice draft distributions from each overpass indicates that summertime melt rates are related to drift track, with more melt occurring in the southern Beaufort Sea than to the north. Additionally, we find that ice surviving summer in the Beaufort Sea since 2007 is similar in thickness to surrounding first‐year sea ice by the end of the following winter. These findings are supported by continuous ice thickness data from ice mass balance buoys. By examining “plumes” of pseudobuoys originating at each mooring location, we identify anomalous northward transport of ice in the southern Beaufort Sea in 2007 that likely contributed to the record‐breaking reduction in sea ice extent that year. We also find that repeat overpasses have been much rarer since 2007, due to reduced summertime sea ice extent in the Beaufort Gyre and possible changes in ice drift patterns. These changes contribute to diminished replenishment of multiyear sea ice volume in the Arctic.
Basement‐Cover Relationships and Their Along‐Strike Changes in the Linking Zone (Iberian Range, Spain): A Combined Structural and Gravimetric Study
Authors: Izquierdo‐Llavall E. , Ayala C. , Pueyo E. L. , Casas‐Sainz A. M. , Oliva‐Urcia B. , Rubio F. , Rodríguez‐Pintó A. , Rey‐Moral C. , Mediato J. F. , García‐Crespo J. 
Published: July 2019

AbstractContractional deformation in the transition between the Iberian and Catalan Coastal Ranges (Linking Zone) generated both thin‐skinned structures detached in low‐strength Triassic units and basement‐involved structures. To evaluate their extent and relative contribution to the overall structure, we carried out a study combining structural geology and gravimetry. New gravity data (938 stations) and density determinations (827 samples) were acquired and combined with previous existing databases to obtain Bouguer anomaly and residual Bouguer anomaly maps of the study area. Seven serial and balanced cross sections were built, their depth geometries being constrained through the 2.5‐D gravity modeling and the 3‐D gravity inversion that we accomplished. The residual Bouguer anomaly map shows a good correlation between basement antiforms and gravity highs whereas negative anomalies mostly correspond to (i) Meso‐Cenozoic synclines and (ii) Neogene‐Quaternary basins. Cross sections depict a southern, thick‐skinned domain where extensional, basement faults inherited from Late Jurassic‐Early Cretaceous times were inverted during the Cenozoic. To the north, we interpret the existence of both Triassic‐detached and basement‐involved deformation domains. The two deformation styles are vertically overlapped in the southernmost part of the Catalan Coastal Ranges but relay both across and along strike in the Eastern Iberian Range. These basement and cover relationships and their along‐strike variations are analyzed in terms of the interplay between structural inheritance, its obliquity to the shortening direction, and the continuity and effectiveness of Triassic décollements in the study area.