bluuebunny/crossref_metadata_2025_split huggingface dataset:
FDG PET and MRI Findings in a Case of Bing-Neel Syndrome
Authors: Bund Caroline , Lhermitte Benoît , De Seze Jérôme , Kremer Stéphane , Namer Izzie-Jacques 
Published: February 2018

Abstract
A 64-year-old man was admitted for expressive aphasia with lack of words. He had been diagnosed with Waldenström 4 years before. At that time, he received 6 cycles of single-agent fludarabine, and remission was obtained. Because of acute expressive aphasia, he underwent brain MRI, which showed frontoparietal and insular subcortical gadolinium enhancement; Bing-Neel syndrome was suspected. Fronto-temporo-insular hypometabolism and left parietal hypometabolism were highlighted on FDG PET/CT. Structural and functional brain imaging revealed impairment of brain areas due to white matter changes and reinforced the diagnosis.
Oligogenic inheritance of congenital heart disease involving a NKX2-5 modifier
Authors: Gifford Casey A. , Ranade Sanjeev S. , Samarakoon Ryan , Salunga Hazel T. , de Soysa T. Yvanka , Huang Yu , Zhou Ping , Elfenbein Aryé , Wyman Stacia K. , Bui Yen Kim , Cordes Metzler Kimberly R. , Ursell Philip , Ivey Kathryn N. , Srivastava Deepak 
Published: February 2018

AbstractComplex genetic inheritance is thought to underlie many human diseases, yet experimental proof of this model has been elusive. Here, we show that a human congenital heart defect, left ventricular non-compaction (LVNC), can be caused by a combination of rare, inherited heterozygous missense single nucleotide variants. Whole exome sequencing of a nuclear family revealed novel single nucleotide variants of MYH7 and MKL2 in an asymptomatic father while the offspring with severe childhood-onset LVNC harbored an additional missense variant in the cardiac transcription factor, NKX2-5, inherited from an unaffected mother. Mice bred to compound heterozygosity for the orthologous missense variants in Myh7 and Mkl2 had mild cardiac pathology; the additional inheritance of the Nkx2-5 variant yielded a more severe LVNC-like phenotype in triple compound heterozygotes. RNA sequencing identified genes associated with endothelial and myocardial development that were dysregulated in hearts from triple heterozygote mice and human induced pluripotent stem cell–derived cardiomyocytes harboring the three variants, with evidence for NKX2-5’s contribution as a modifier on the molecular level. These studies demonstrate that the deployment of efficient gene editing tools can provide experimental evidence for complex inheritance of human disease.One sentence summaryA combination of three inherited heterozygous missense single nucleotide variants underlying a familial congenital heart defect.
Post-purchase shipping and customer service experiences in online shopping and their impact on customer satisfaction
Authors: Cao Yingxia , Ajjan Haya , Hong Paul 
Published: February 2018

Purpose
The purpose of this paper is to understand the role of post-purchase logistic services on customer satisfaction and future purchase decision, to reveal any differences across China and Taiwan, to fill in a gap in the literature focused on post-purchase logistic activities related to shipping, return, and tracking, to provide managerial guidance in logistics for e-commerce, and to develop insights on logistic services for future research.

Design/methodology/approach
Using a validated survey instrument, 384 respondents in China and 145 respondents in Taiwan are collected. The research model is analyzed using component-based estimation approach to structural equation modeling.

Findings
The structural equation analysis of the study found that post-purchase shipping and tracking have an impact on customer satisfaction in both China and Taiwan. It also found that customer service is the most significant factor among the examined antecedents for online shoppers in China. While, return service is more important for shoppers in Taiwan. Finally, customer satisfaction played a stronger positive role for online shoppers in Taiwan as compared to their counterparts in China.

Research limitations/implications
This research extended the current literature about post-purchase logistic services in an online shopping environment with a literature-based research model and good empirical data support. However, one limitation of the study is that the data collected represents a cross-sectional sample; future research should examine longitudinal sample to study customers’ purchase intentions over time.

Practical implications
This study can help both scholars and practitioners understand the importance of tracking, return, shipping, and customer service in an online shopping environment and across countries. It provides insights on designing e-commerce relevant shipping services to satisfy and attract customers across countries.

Originality/value
The study investigated how post-purchase activities contributed to customer satisfaction in online shopping and explored the influence of customer satisfaction on future purchase intention in China and Taiwan. This is one of the first studies available in the literature to provide empirical support and managerial insights about post-purchase activities related to shipping, tracking, and returns for e-commerce with cross-regional comparison.
Cost performance of building refurbishment works: the case of Malaysia
Authors: Ali Azlan Shah , Azmi Nur Farhana , Baaki Timothy Kurannen 
Published: February 2018

Purpose
Refurbishment is inherently more sustainable than building new. However, planned and actual costs of refurbishment projects are bound to vary due to the complex nature of most such projects. This can affect the performance of refurbishment work. The purpose of this paper is to examine factors responsible for elemental cost variations between the actual and planned costs of refurbishment projects. The study also examines factors that contribute to differences in actual and planned cost between refurbishment and new build projects.

Design/methodology/approach
A quantitative approach was adopted for this study. A literature review identified factors responsible for elemental cost variations in refurbishment projects, as well as factors responsible for differences in actual and planned cost of new build and refurbishment projects. This was followed by a questionnaire survey of refurbishment projects across Malaysia. A total of 55 respondents provided input through a questionnaire survey to identify these factors.

Findings
This study demonstrates that procurement strategy (PS), inappropriate contractors (IC), poor project management (PPM), availability of funding, materials and equipment, and force majeure (FM) significantly affect refurbishment cost performance. Electrical installations, firefighting equipment, and painting were the building elements most affected by cost variations. A regression model for refurbishment cost prediction indicates that PS, IC, PPM, availability of funding, materials and equipment, and FM were significant predictors of building refurbishment cost performance.

Originality/value
This paper provides insight into the major factors affecting elemental cost variation of refurbishment works, as well as building elements most affected by cost variations and provides a model for predicting refurbishment cost performance.
Remediation and protection of masonry structures with crystallising moisture blocking treatment
Authors: Al-Kheetan Mazen J. , Rahman Mujib M. , Chamberlain Denis A. 
Published: February 2018

Purpose
The purpose of this paper is to investigate the performance of new and innovative crystallising materials, so-called moisture blockers, in protecting masonry structures from water ingress.

Design/methodology/approach
Two masonry wells were constructed: one with lime mortar and the other with cement-based mortar in order to hold water inside, and then a moisture blocking product was applied at dry and wet conditions to the negative hydrostatic pressure side. The moisture levels of both, the surfaces and the substrate, were then observed for 14 days.

Findings
Results demonstrated that moisture blocking materials are effective methods in reducing the levels of surface moisture for bricks, mortar-brick interface and mortar.

Originality/value
Moisture blockers use the available water in the masonry to block the passage of water to the surface of the masonry, filling pores, cracks and spaces at the interface between mortar and bricks. This approach will deliver a wider understanding of how water-based moisture blockers work and the scenarios in which they are best applied. The pursuit of possible environmentally friendly and sustainable materials for use in the construction industry is the key driver of this research.
Integrating BIM into facility management
Authors: Hosseini M. Reza , Roelvink Rogier , Papadonikolaki Eleni , Edwards David John , Pärn Erika 
Published: February 2018

PurposeIntegrating building information modelling (BIM) into facility management (FM) has generated fervent debate within the extant literature given an increasing realisation amongst practitioners that the majority of BIM benefits reside within the whole lifecycle management. Converting a building’s in-use data and information into tangible business knowledge to augment FM performance is crucial for business growth and prosperity. Yet curiously, scant academic attention has been paid in investigating the data and information hand-over process through BIM required by FM. The purpose of this paper is to address this knowledge gap.Design/methodology/approachThe research approach adopted draws upon pertinent BIM in the FM literature and a qualitative discourse accrued via focus group meetings of Australian FM experts.FindingsThe study’s findings are presented as a data and information typology matrix that captures the associations among different forms of data ownership, FM service delivery categories and data and information typologies for using BIM in FM.Practical implicationsThe analysis results will prove invaluable for policy-makers, researchers and practitioners by providing a relevant data and information typology and capturing the complex associations in the process of integrating BIM into FM.Originality/valueThis study contributes to the field by providing a better understanding of different forms of data and information, required by members of a FM team. The original insight shared here is the necessity to consider a distinctive array of interests and the potential for using different forms of data and information when integrating BIM into FM.
Developing an effective renovation plan: the influence of data collection tools
Authors: Ogbeifun Edoghogho , Mbohwa Charles , Pretorius Jan-Harm Christiaan 
Published: February 2018

PurposeAll built facility begins to show signs of deterioration immediately after the facility is completed and put to use, thus necessitating routine maintenance. Increase in defects due to age, usage, and other factors, requires extensive maintenance activities known as renovation. The data used for a typical renovation plan can be collected using the condition assessment (CA) tool which depends on physical inspection of the defects or through a facility condition index which hinges on harnessing and analyzing the information in the operational history of the facility. The purpose of this paper is to examine the quality of a typical renovation plan using both tools.Design/methodology/approachThe single case study of qualitative research was adopted. The data were collected through the principle of semi-structured questionnaire complemented with interviews and document analysis. The documents include periodic operational reports and a CA report used for planned renovation exercise of the Facilities Management (FM) Unit in a higher education institution in South Africa.FindingsThe findings revealed that although the FM Unit produces periodic reports, but there was no evidence of detailed analysis of the reports. Therefore, the programmed renovation exercises are based purely on the information from a CA.Research limitations/implicationsThis research is a single site case study of qualitative research; the data collected are limited and not sufficient for generalization of the results. Furthermore, the lack of record of the analysis of the operational history in the periodic reports negatively affected the computation of facilities condition index (FCI). Thus it was not possible to demonstrate the strength of FCI over CA from empirical information.Originality/valueThe quality of a typical renovation plan is influenced by the tool used for data collection. Although the CA tool is commonly used, experience shows that the renovation exercise developed from such records is prone to many execution setbacks, such as frequent scope changes and the associated cost and time overruns. These setbacks can be minimized if the FCI is used as the tool for data collection.
The effects of travel experience dimensions on tourist satisfaction and destination loyalty: the case of an island destination
Authors: Sangpikul Aswin 
Published: February 2018

PurposeThis paper aims to examine the effects of travel experience dimensions on tourist satisfaction and destination loyalty.Design/methodology/approachData were collected from 457 international tourists visiting Phuket through a convenience sampling method. The structural equation modeling approach by AMOS was used to test the effects.FindingsIn case of island destination, beach attraction is not the only factor contributing to tourists’ loyalty, but hospitality of local people also plays an essential component to retain loyal tourists.Research limitations/implicationsThis study examined only one construct (i.e. travel experience) affecting tourist satisfaction and destination loyalty.Practical implicationsTourist experience in beach attractions and local people are the key factors to retain royal tourists.Social implicationsQuality of beaches and friendliness of local people are important factors to promote island tourism.Originality/valueTwo key factors of tourist experience were found to affect tourists’ loyalty in the case of island destination: beach attractions and local people.
Application of visual methods to perceptions of tourism development
Authors: Hillman Peita , Moyle Brent D. , Weiler Betty 
Published: February 2018

Purpose
The purpose of this study is to explore the benefits and drawbacks of visual methods, specifically architectural drawings, for assessing locals’ perceptions of proposed tourism development in a cultural tourism precinct.

Design/methodology/approach
To explore the use of visual methods 21 in-depth interviews were conducted with locals working in the tourism industry in Ubud, Bali. During the interviews, respondents were shown a series of architectural drawings depicting a new Western-branded hotel development.

Findings
The use of visual methods, specifically architectural drawings to gauge reactions from respondents revealed mixed levels of support for future tourism development. Respondents were supportive of an increase in visitors but were cautious about the nature of new development.

Research limitations/implications
Visual research methods should also be considered in an interview setting to supplement traditional questioning techniques.

Originality/value
This study provides an outline of how visual methods can either support or detract from qualitative methodologies and allow for a considered design if incorporated into future studies.
The role of aesthetic experiential qualities for tourist satisfaction and loyalty
Authors: Breiby Monica Adele , Slåtten Terje 
Published: February 2018

PurposeThe aim of this study is to examine the role of aesthetic experiential qualities for tourist overall satisfaction and three types of loyalty.Design/methodology/approachA national tourist route in Norway was chosen as an empirical context for this study. Totally, the role of five aesthetic experiential qualities were examined, namely, scenery, cleanliness harmony, art/architecture and genuineness.FindingsThe findings reveal that the three aesthetic experiential qualities, scenery, harmony and genuineness, were all positively related to tourist overall satisfaction with the tourist road. Moreover, tourist overall satisfaction had a direct influence on three types of loyalty, referring to tourists’ intentions to recommend the tourist road to other, to revisit same tourist road and to visit similar tourist roads in the future. However, the findings reveal that only two aesthetic qualities, cleanliness and genuineness, had a direct effect on intention to revisit the same tourist road, and thus indicates a more complex explanatory pattern concerning tourist loyalty.Research limitations/implicationsThis study is limited to five aesthetic experiential qualities in a specific nature-based tourist context. The results open up some of the areas for future research on the role of aesthetics in man-made environments (in addition to the natural environment) in nature-based tourism. When most of the other variables are similar, aesthetic experiential qualities may make a difference to a nature-based product’s performance, and thus provide the competitive edge.Practical implicationsDestination managers and marketers should focus on aesthetic experiential qualities to increase tourist satisfaction and loyalty, and thereby strengthen a destination competitiveness and value creation.Originality/valueResponding to the need to focus on aesthetic experiential qualities in a nature-based tourism context, this study measures the effects of the aesthetic experiential qualities for tourist satisfaction and loyalty in an original destination setting.
Supply chain risk’s impact on corporate financial performance
Authors: Chen Hong Long 
Published: February 2018

PurposeResearchers have long sought to understand how risks in supply chains (SCs) affect firm performance. Yet, they have not fully subjected claims of how SC risks affect firm financial performance to theoretical and empirical scrutiny. The purpose of this paper is to investigate the links between SC risks and firm financial performance.Design/methodology/approachThe author analyzes how SC risks affect firm financial performance from the perspective of marginal financial performance (MFP) using survey and financial statement data. The author employs structural equation modeling to examine the hypotheses using 106 Taiwanese listed companies across 20 industries.FindingsThe findings regarding the importance of industry-specific risk, organizational risk, internal business process risk, and demand risk are consistent with prior studies. The author finds that demand risk has an MFP of −0.20, the highest negative effect among the risk variables. The findings also show that industry-specific risk possesses an MFP of −0.16, the second-highest negative effect, despite having no direct effect on financial performance.Research limitations/implicationsThis paper examines how SC risks affect MFP via combining survey and financial statement data. It does not assume the reported MFP estimates apply to all businesses in other countries. However, future research could triangulate our findings.Originality/valueThis study combines survey and financial data to analyze how SC risks affect firm financial performance. Specifically, it provides a methodology for estimating quantitative cause-effect relationships between SC risk and firm financial performance, an important topic that receives less research interest in the field of supply chain management.
The diffusion network of research knowledge in operations management
Authors: Pilkington Alan , Meredith Jack R. 
Published: February 2018

Purpose
The purpose of this paper is to examine how the research knowledge in OM has been obtained and distributed since the first journals in OM began publication in 1980, changes in the interests of OM over the decades and where they are heading in the future; and to explore the changing roles of individual journals in the development of OM.

Design/methodology/approach
A two-stage bibliometric study was employed, first using citation analysis to examine the changing research interests in OM through an analysis of the OM journals. Then the top journals of most importance to OM were analyzed to determine the role that each one played in the knowledge distribution network and how that changed over the decades.

Findings
OM’s journal base consists of 7 research knowledge sources, 12 transmitters linking different journal groups, and 11 sinks with limited input. Research attention changed from practice, engineering, and OR to general management, strategy, and production management in the 2000s, with strategy, organizational issues, and logistics surfacing in the 2010s. OM features increasingly academic research with less interest in practice. OM journals’ network importance has increased substantially, with JOM now a bridge between the quantitative and management journals.

Practical implications
Both researchers and managers gain in understanding the history and identifying the future direction of OM, as well as which journals will have the most relevant papers to their interests.

Originality/value
This research identifies the history of the OM field in terms of its constituents and where it is going in the future. This history is related to the role OM plays among the knowledge network of top journals and presents a novel way of classifying and labeling journals based on their contribution.
Modeling management behaviors in lean production environments
Authors: Camuffo Arnaldo , Gerli Fabrizio 
Published: February 2018

PurposeThe purpose of this paper is to identify and empirically validate a repertoire of management behaviors associated with the adoption of lean systems, showing how a subset of such behaviors differentiates more advanced lean systems in a specific setting.Design/methodology/approachThe study applies regression analysis and non-parametric hypothesis testing to an original data set coming from field research of 26 cases of adoption of lean operations practices.FindingsThe study: identifies in the lean literature a repertoire of management behaviors that support lean implementations and complement the adoption of lean practices; provides a way to operationalize them; validates this repertoire of behaviors; and shows that a subset of these behaviors is associated with more advanced lean implementations, suggesting the necessity to adopt a situational approach to lean leadership.Research limitations/implicationsThe findings have boundary conditions, defined by the national, industrial, and size context in which the study was conducted.Practical implicationsThe study provides practical guidance for lean system implementation suggesting a repertoire of management behaviors within which firms can identify and validate specific, appropriate subsets of behaviors aligned with the company strategy, culture, size, environment, bundle of lean operation practices adopted, and maturity stage of lean adoption.Originality/valueThis is the first study to provide quantitative, non-anecdotal evidence of the relationship between specific management behaviors and the successful implementation of lean operations practices. It offers a novel method to operationalize and measure lean management behaviors.