bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fabrikasi Nanotubes Titanium Dioksida (TiO2) Menggunakan Metode Hidrotermal
Authors: Setyani Atik , Wibowo Emas Agus Prastyo 
Published: November 2018

Nanotubes received great attention because it has a high surface area. In this study, TiO2 nanotubes fabricated via hydrothermal method from synthesis of TiO2 nanoparticles via sol-gel method. Catalysts that have been synthesized later in the characterization by X-Ray Diffraction (XRD) to obtain the crystal size and crystallinity. Crystal size of TiO2 nanoparticles at a temperature of 450C is 13.78 nm. Then characterized by Transmission Electron Microscopy (TEM) to look at the formation of nanotubes. Characterization of TiO2 nanotubes with TEM shows that the structure of the tubes had already been formed TNTs although the growth has not been perfect. It can be seen from the structure TNTs who tend to be short and yet so irregular.DOI: http://dx.doi.org/10.15408/jkv.v0i0.5036
O melhor da hospitalização: contribuições do brincar para o enfrentamento da quimioterapia
Authors: Sposito Amanda Mota Pacciulio , Nascimento Lucila Castanheira , Garcia-Schinzari Nathália Rodrigues , Mitre Rosa Maria de Araujo , Pfeifer Luzia Iara , Lima Regina Aparecida Garcia de 
Published: November 2018

Objetivo: la quimioterapia es una terapia bastante utilizada en el tratamiento del cáncer infantil y, aunque eficaz, provoca efectos colaterales y exige una reestructuración de lo cotidiano. El objetivo del estudio es comprender el juego como estrategia para enfrentar el tratamiento de laquimioterapia en niños.Método: estudio exploratorio con análisis cualitativo de datos. Participaron diez niños entre siete y doce añoscon cáncer, en tratamiento quimioterapéutico y hospitalizados. Fueron llevadas a cabo entrevistas semiestructuradas utilizando títeres como recurso facilitador de la comunicación. En el análisis de los datos, del tipo temática inductiva, se destacó la importancia del juego como facilitador del enfrentamiento a la quimioterapia.Resultados: los niños se refirieron a la relevancia del juego para combatir el ocio y destacaron la importancia de un espacio lúdico, adaptado a las necesidades del tratamiento dentro del ambiente hospitalario. La actuación del terapeuta ocupacional y de voluntarios caracterizados como clowns (payasos) fue citada como diferencial en este contexto.Consideraciones Finales: se destaca la importanciade inversión, por parte de la administración de los hospitales, en espacios y materiales lúdicos y en la contratación de personal cualificado para facilitar el juego en los niñoshospitalizados.
Ações desenvolvidas por cuidadores de idosos institucionalizados no Brasil
Authors: Alves Amanda Karolina Torres de Medeiros , Esmeraldo Candice Alves , Costa Mariela Samantha De Carvalho , Honório Mônica Larissa Padilha , Nunes Vilani Medeiros de Araújo , Freitas Anna Alice Lessa de , Pimenta Isac Davidson Santiago Fernandes , Bezerra Isaac Newton Machado , Piuvezam Grasiela 
Published: November 2018

Objetivo: analizar las acciones realizadas por cuidadores de ancianos dirigidas a residentes de instituciones de larga estancia para ancianos (ILEA) en Brasil.Metodología: estudio de naturaleza cualitativa con análisis de datos cuantitativo, clasificado como observacionaly analítico, desarrollado en 36 ILEA seleccionadas en 11 municipios brasileños de medio y gran porte, distribuidas en las 5 regiones geográficas.Se realizaron entrevistas a los cuidadores en el periodo 2008-2011. El análisis del material discursivo (corpus) fue mediado por el software de análisis cuantitativo de datos textualesAnalyse Lexicale par Contexte d’un Ensemble de Segments de Texte (ALCESTE), la versión 4.9 para Windows.Resultados: los participantes fueron 117 cuidadores de ancianos de las ILEA estudiadas. La mayoría de los cuidadores son mujeres y trabajan en ILEA sin ánimo de lucro (filantrópicas). El material textual originó 5 clases semánticas que se dividieron en dos ejes fundamentales. El primer eje se denominó “asistencia a la salud de ancianos institucionalizados” y el segundo eje “actividades habituales de cuidadores en las ILEA”.Conclusiones: los discursos evidenciaron que las principales acciones realizadas están relacionadas con el cuidado directo al anciano, como la alimentación, higiene personal –bucal y general– y administración de medicamentos. Además, la alud bucal ocupa un lugar de relevancia para los cuidadores, a pesar de que relaten dificultades para realizar esta práctica.
Saúde mental e qualidade de vida de pessoas idosas
Authors: Gato Jussara Marília , Zenevicz Leoni Terezinha , Faganello Madureira Valéria Silvana , Gaffuri da Silva Tatiana , Sedrez Celich Kátia Lilian , Silva de Souza Sílvia , Martins Furlan de Léo Marcela 
Published: November 2018

Objetivo: evaluar estado de salud mental, índice de depresión, humor y calidad de vida (CV) de ancianos.Metodología: estudio transversal cuantitativo realizado con 122 personas con más de 60 años, atendidas por la atención primaria. Los datos se recolectaron con inventarios de evaluación de CV (WHOQOL-OLD/WHOQOL-BREF), Escala de Depresión Geriátrica y cuestionario sociodemográfico y clínico. El análisis de los datos se ejecutó medianteestadística descriptiva.Resultados: la mayoría se considera saludable, aunque el 40,2 % presenta agravios a la salud, 55,6 % utiliza ansiolíticos y antidepresivos y 61,5 % presenta depresión, asociada estadísticamente a pertenecer al sexo femenino, estado civil viudo/soltero/divorciado, vivir solo y no practicaractividades de ocio y comunitarias. La depresión fue inversamente asociada al estado civil casado, residir con otraspersonas y a la práctica de actividad física y de ocio. Hubo fuerte asociación entre aumento de la intensidad de los síntomas depresivos y disminución de la CV en todos los ámbitos. La satisfacción con su CV fue moderada, con mayor puntuación en ‘relaciones sociales’ y menor en el dominio ‘físico’. En WHOQOL-OLD hubo puntuaciones medias más altas en los dominios ‘intimidad’ y ‘participación social’ y menor puntuación en el dominio ‘muerte y morir’.Conclusión: la percepción de mejor CV se asocia a la edad, estado civil, autopercepción de ‘estar saludable’ y ausenciade depresión. Tabaquismo se relaciona con peor CV en todos los ámbitos. La relación entre consumo de alcohol y mejor evaluación en el dominio ‘muerte y morir’ necesita ser elucidada.
Keragaman Jenis Burung Pada Berbagai Komunitas di Pulau Sangiang, Provinsi Banten
Authors: Fikriyanti Mariana , Wulandari Wulandari , Fauzi Irpan , Rahmat Ade 
Published: November 2018

Burung merupakan satwa liar yang banyak ditemukan diberbagai tipe habitat. Indonesia sendiri merupakan rumah bagi 17% spesies burung yang ada di muka bumi. Keragaman jenis burung pada suatu komunitas juga dapat menjadi indikator lingkungan. Penelitian ini bertujuan untuk mengetahui keragaman jenis burung pada berbagai tipe komunitas yang terdapat di Pulau Sangiang, Banten. Komunitas yang diamati yaitu komunitas hutan dataran rendah, kebun dan hutan mangrove. Metode yang digunakan adalah metode Point Count, dimana pada tiap komunitas ditentukan sebanyak enam titik hitung yang mempunyai jarak sekitar 200 m tiap titik hitungnya. Berdasarkan penelitian ini didapatkan 52 spesies burung dari 31 famili yang tersebar di masing-masing ekosistem. Dari ketiga komunitas, indeks keanekaragaman tertinggi dijumpai pada ekosistem kebun yaitu senilai 2.76, ekosistem mangrove dengan nilai 2,61 dan indeks keanekaragaman paling rendah terdapat pada ekosistem dataran rendah dengan nilai indeks keanekaragaman 2.56. Secara keseluruhan dapat disimpulkan bahwa persebaran jenis burung pada tiap komunitas merata yang ditunjukkan oleh indeks kemerataan pada masing-masing tipe komunitas yang nilainya mendekati satu.
PENILAIAN SOSIAL DALAM MEMBANGUN ENTITAS BISNIS PERIKANAN PADA SKPT SELAT LAMPA, NATUNA
Authors: Zulham Armen 
Published: November 2018

Kehadiran nelayan China, Vietnam dan Thailand, pelaku illegal fishing pada Laut Natuna Utara merupakan sinyal bahwa ikan pada perairan tersebut cukup potensial. Keberhasilan memerangi Illegal Unreported and Unregulated fishing (IUU- Fishing) pada perairan itu, seharusnya mendorong entitas bisnis perikanan Natuna berperan memanfaatkan keberhasilan tersebut. Namun, peran itu belum terwujud, karena struktur sosial dan jaringan sosial pelaku usaha perikanan Natuna kapasitasnya belum dipetakan. Pemetaan ini diperlukan untuk: (a). menilai kemampuan pemupukan modal. (b).mengetahui kemampuan akses sumberdaya ikan di Laut Natuna Utara. (c). memahami perkembangan industri pengolahan di Natuna. (d). mengetahui pelaku yang mempunyai akses pasar dan jaringan perdagangan ikan. (e). memahami perilaku bisnis pelaku usaha perikanan di Natuna. Upaya meningkatkan peran pelaku usaha perikanan di Natuna, dilaksanakan melalui program Sentra Kelautan dan Perikanan Terpadu (SKPT) di Selat Lampa. Kontruksi sosial SKPT tersebut, diwujudkan penuh tantangan karena struktur sosialnya masih premature. Sementara struktur sosial dan jaringan bisnis perikanan diluar SKPT telah mapan. Assessment sosial ini, bertujuan memberi informasi tentang struktur sosial dan jaringan sosial perikanan Natuna diluar SKPT Selat Lampa, sebagai bahan untuk memfungsikan SKPT tersebut. Tulisan ini menggunakan data survey dan diskusi pelaku bisnis perikanan di Natuna pada pada bulan Oktober 2017. Hasil analisis merekomendasikan pedagang besar pada jaringan bisnis ikan di Natuna harus diintegrasikan dalam entitas bisnis usaha patungan, sebagai wadah mereka berperan di SKPT Selat Lampa
Design and Optimization of a Direct-Conversion Double-Balanced Mixer for RF Receiver Front-End
Authors: Gomez Frederick Ray 
Published: November 2018

Differential implementation is becoming highly favoured in RFIC (radio frequency integrated circuit) design, notably its high immunity to common-mode noises, acceptable rejection of parasitic coupling, and increased dynamic range. One specific RF front-end building block that is usually designed as a differential circuit is the mixer. This technical paper presents a study of a differential mixer, notably the double-balanced mixer implemented on a direct-conversion architecture in a standard 90nm CMOS (complementary metal-oxide semiconductor) process. Operating frequency is set at 5GHz, which is a typical frequency for RF (radio frequency) receiver. Impedance matching was essential to fully optimize the mixer design. The direct-conversion double-balance mixer design eventually achieved conversion gain of 11.463dB and noise figure of 16.529dB, comparable to mixer designs from past research and studies.
O TEMPO E O MEDO: a longa duração da guerra em Moçambique
Authors: THOMAZ OMAR RIBEIRO 
Published: November 2018

Neste ensaio, partindo de trabalhos etnográficos realizados nos últimos 15 anos entre as regiões sul e centro de Moçambique, argumento que a percepção da passagem do tempo e o constante medo da desordem se entrelaçam em narrativas e rumores que conectam diferentes momentos da história deste paá­s. É por meio de seu avesso ”“ da guerra, ou do medo da guerra ”“ que se fala de um ideal de comunidade sempre frágil, sempre inconcluso.Palavras-chave: Tempo. Medo. Guerra. Moçambique. TIME AND FEAR: the long duration of the war in MozambiqueAbstract: In this essay, based on ethnographic works carried out in the last 15 years between the southern and central regions of Mozambique, I argue that the perception of the passage of time and the constant fear of disorder are intertwined in narratives and rumors that connect different moments of the history of this parents. It is through its reverse - war, or fear of war - that we speak of an always fragile, always unfinished ideal of community.Keywords: Time. Fear. War. Mozambique. EL TIEMPO Y EL MIEDO: la longa duración de la guerra en MozambiqueResumen: En este ensayo, partiendo de trabajos etnográficos realizados en los últimos 15 años entre las regiones sur y centro de Mozambique, argumento que la percepción del paso del tiempo y el constante miedo del desorden se entrelazan en narrativas y rumores que conectan diferentes momentos de la historia de éste paá­s. Es por medio de su revés - de la guerra, o del miedo a la guerra - que se habla de un ideal de comunidad siempre frágil, siempre inconcluso.Palabras clave: Tiempo. El miedo. Guerra. Mozambique.
Value chain analysis of weaving industry
Authors: Rini Diah Ayu , Budiani Sri Rahayu 
Published: November 2018

Value chain analysis is used to discover the distribution of the supply of raw materials and the marketing of industrial products. The research study focus was located in Gamplong Tourism Village, Sleman regency, Daerah Istimewa Yogyakarta. The aims of this research were to 1) map the value chain of the weaving industry in Gamplong Tourism Village; 2) to identify existing obstacles to the weaving industry in Gamplong Tourism Village and 3) to determine appropriate strategies to minimise the obstacles in the weaving industry in Gamplong Tourism Village. The analysis used in this research was a descriptive analysis. The respondents in this study were 47 industry actors, the distributors of raw materials and marketing individuals. Data collection was conducted using a census and in-depth interviews with the weaving industry actors. This was snowballed to the distributor. Based on the results of the research, the value chain of the weaving industrial products as a whole consists of six actors, namely raw material suppliers, raw material distributors, weaving industry actors, distributors, retail traders, and consumers. The household industry value chain diﬀers from the small and medium industry value chain. Some of the obstacles to the Gamplong weaving industry are the length of the value chain, no labour regeneration, and less tourism village development. Therefore, strategies to reduce these obstacles include cutting down the value chains, managing human resources, and increasing the promotion strategies used.
Functional and morphological retinal impairment following resolved chronic central serous chorioretinopathy
Authors: Gawęcki Maciej , Jaszczuk-Maciejewska Agnieszka , Jurska-Jaśko Anna , Kneba Małgorzata , Grzybowski Andrzej 
Published: November 2018

Abstract
Purpose
Central serous chorioretinopathy is a complex ocular entity that, in its chronic form, can lead to serious visual impairment and morphological damage to the retina.
The aim of the current retrospective study was to evaluate the damage present after long-standing but resolved central serous chorioretinopathy. Correlations between measurable factors—for example, duration of the disease, baseline retinal morphological parameters, or patient age and/or their degree of impairment—were also assessed.
Materials and methods
Thirty-two eyes with chronic central serous chorioretinopathy in which complete resolution of subretinal fluid was achieved after subthreshold micropulse laser treatment were analyzed according to final best-corrected visual acuity and retinal morphological parameters as measured by spectral optical coherence tomography with angiography option (OCTA). Results were compared with the outcomes of a control group. Statistical analysis included regarding correlation between final visual acuity and final central retinal thickness and retinal and functional parameters prior to treatment.
Results
Final best-corrected visual acuity after chronic central serous chorioretinopathy was 0.23 logMAR (0.6 Snellen) and central retinal thickness was 39.32 µm smaller than in controls. No correlation was found between final visual acuity and retinal thickness and duration of the disease, patient age, and baseline morphological retinal parameters. OCTA scans revealed impaired choroidal perfusion even following resolution of the disease.
Conclusion
Chronic central serous chorioretinopathy is a potentially damaging clinical entity that results in serious visual impairment, retinal thinning, and choroidal flow defects. No significant correlation between duration of central serous chorioretinopathy and amount of visual deficit has been found, therefore it is possible that the biggest damage occurs within the first months of active chorioretinopathy.

Keywords: chronic central serous chorioretinopathy, micropulse laser, central retinal thickness, subretinal fluid
Subjective symptom impact on quality of life in patients with myotonic dystrophy
Authors: Fujino Haruo , Saito Toshio , Takahashi Masanori P. , Takada Hiroto , Nakayama Takahiro , Imura Osamu , Matsumura Tsuyoshi 
Published: November 2018

Abstract
Background: Although functional impairment in patients with myotonic dystrophy is an important determinant of quality of life (QoL), it is possible that QoL could further be influenced by the subjective evaluation of symptoms. The aim of this study was to investigate the subjective symptom impact on the QoL, after controlling for functional impairment.
Methods: Eligible patients with myotonic dystrophy type 1 (DM1) were recruited from four hospitals in Japan. Subjective symptom impact across four domains (muscle weakness, fatigue, pain, and myotonia) and overall QoL were evaluated using the Individualized Neuromuscular Quality of Life (INQoL) questionnaire. Functional impairment was assessed using the modified Rankin scale.
Results: Eighty-six patients with DM1 were included in this study. On multiple regression analysis, a portion of the variance in the overall QoL was significantly accounted for by demographic variables and functional impairment (adjusted R2 = 0.32). In addition to these variables, subjective symptom impact (muscular weakness, fatigue, and myotonia) explained additional variance in the overall QoL (adjusted R2 = 0.80). Difficulties in activities of daily living and participation caused by each symptom consistently predicted overall QoL across three symptom domains (muscular weakness, fatigue, and myotonia).
Conclusions: Subjective symptom impact needs to be considered, in addition to functional impairment, when evaluating the QoL of patients with DM1.
Which is the best parameter on CT scan to predict dysthyroid optic neuropathy?
Authors: Yu Bo , Gong Can , Chen Yingbai , Ma Yingjie , Wu Wencan , Tu Yunhai 
Published: November 2018

Abstract
Background: To evaluate the value of parameters on CT scan in predicting dysthyroid optic neuropathy (DON), such as muscle index (MI), superior ophthalmic vein (SOV) dilatation, extraocular muscle volume/ orbit volume (MV/OV) and intracranial fat prolapse. To provide guidance for early diagnosis of DON accordingly.
Methods: A total of 67 eyes of 35 patients with thyroid-associated ophthalmopathy (TAO) were included in this study. Patients were divided into 2 groups (DON group and non-DON group). Parameters were measured on HRCT, including MI, SOV dilation, MV/OV and intracranial fat prolapsed, and compared between these 2 groups. The relation between those parameters and visual function (visual acuity (VA) and visual field defect (VF defect)) were also evaluated.
Results: MI and MV/OV were significantly higher in DON group (P=0.00035 and P=0.00026). No significant difference was detected regarding intracranial fat prolapse existence and SOV dilatation (P=0.36899 and P=0.14594). MV/OV was found to have significant negative correlation with both VF defect(P=0.02730) and VA (P=0.0000) while MI was found to have weak negative linear correlation with VA only (P=0.00017). The area under ROC (receiver operating characteristic) curves was 0.82 for MV/OV and 0.75 for MI. The best performance in detecting DON was achieved when MV/OV is set at 0.20 with 72% sensitivity and 87% specificity and MI is set at 0.52 with 64% sensitivity and 80% specificity.
Conclusion: MI and MV/OV are predictive parameters for DON. Together with clinical manifestations, MV/OV≥0.2 can be used as a good indicator for DON in TAO patients.
Different EPHX1 methylation levels in promoter area between carbamazepine-resistant epilepsy group and carbamazepine-sensitive epilepsy group in Chinese Population
Authors: Lv Yudan , Zheng Xiangyu , Shi Mingchao , Wang Zang , Cui Li 
Published: November 2018

Abstract
Background: Epigenetics underlying refractory epilepsy is poorly understood. DNA methylation may affect gene expression in epilepsy patients without affecting DNA sequences. Herein, we investigated the association between Carbamazepine-resistant (CBZ-resistant) epilepsy and EPHX1 methylation in a northern Han Chinese population, and conducted an analysis of clinical risk factors for CBZ-resistant epilepsy.
Methods: 75 northern Han Chinese patients participated in this research. 25 cases were CBZ-resistant epilepsy, 25 cases were CBZ-sensitive epilepsy and the remaining 25 cases were controls. Using a CpG searcher was to make a prediction of CpG islands; bisulfite sequencing PCR (BSP) was applied to test the methylation of EPHX1. We then did statistical analysis between clinical parameters and EPHX1 methylation.
Results: There was no difference between CBZ-resistant patients,CBZ-sensitive patients and healthy controls in matched age and gender. However, a significant difference of methylation levels located in NC_000001.11 (225806929.....225807108) of the EPHX1 promoter was found in CBZ-resistant patients, which was much higher than CBZ-sensitive and controls. Additionally, there was a significant positive correlation between seizure frequency, disease course and EPHX1 methylation in CBZ-resistant group.
Conclusion: Methylation levels in EPHX1 promoter associated with CBZ-resistant epilepsy significantly. EPHX1 methylation may be the potential marker for CBZ resistance prior to the CBZ therapy and potential target for treatments.
Erenumab safety and efficacy in migraine: a systematic review and meta-analysis of randomized clinical trials
Authors: Zhu Changyu , Guan Jianmei , Xiao Hua , Luo Weinan , Tong Rongsheng 
Published: November 2018

Abstract
Background: Erenumab is a new medicine approved lately in the US for the preventive treatment of migraine in adults. We aimed to conduct a meta-analysis to evaluate the efficacy and safety of erenumab in patients with migraine.
Methods: The electronic database composed of PubMed, Embase and Cochrane library was independently retrieved by two reviewers. Only randomized controlled trials (RCTs) that compared between placebo and erenumab were included in this analysis. mean differences (MDs) and Pooled risk ratios (RRs) as well as their corresponding 95% confidence intervals (CIs) were calculated for continuous and dichotomous data, respectively.
Results: Total five RCTs representing 2928 patients were included. Pooled analysis showed significant reductions of the 50% reduction(RR 1.55; 95%CI,1.35 to 1.77; P < 0.00001; I²=49%). In addition, the mean monthly migraine days (MMMDs) from baseline in the erenumab group compared with placebo (MD -1.32, 95%CI, -1.73 to -0.91; P < 0.00001; I²=100%) and migraine-specific medication days (MSMDs) from baseline (MD -1.41; 95%CI, -1.80 to -1.02; P＜0.00001; I²=100%) were significantly increased for the erenumab group compared with placebo. Furthermore, there was significant reduction of MSMDs from baseline in 140mg erenumab group compared to 70mg (MD=0.55; 95%CI:0.54 to 0.66; Z =10.95; P<0.00001; I²=90% ). Finally, there were no significant differences between erenumab group and placebo of any adverse events and serious adverse events.
Conclusion: Among patients with migraine, both 70mg and 140mg erenumab are associated with reduction of MMMDs, MSMDs from baseline and increased rate of 50% reduction without increased risk of any adverse events and serious adverse events.