bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of financial risk attitude and financial behavior as mediators in financial satisfaction
Authors: Saurabh Kumar , Nandan Tanuj 
Published: June 2018

Purpose
The purpose of this paper is to examine the relationships between financial knowledge, socialization and financial satisfaction with financial risk attitude and financial behavior as a mediator after demonetization and introduction of GST.

Design/methodology/approach
The sample consisted responses of 286 individuals from the city of Allahabad, Uttar Pradesh, India and making financial decisions for the household for at least last two years. The data were analyzed using exploratory factor analysis and mediation regression analysis.

Findings
All sub-scales used to measure constructs had satisfactory reliabilities and internal consistencies. It was found that financial risk attitude and financial behavior both mediate the relationship between financial socialization and financial satisfaction as well as between financial knowledge and financial satisfaction.

Research limitations/implications
This research is based upon survey method and voluntary participation. Hence one can question generalization of findings to larger samples. Moreover, the study is limited to a restricted geographical region which could affect the generalization of findings.

Practical implications
Results provide insights into the antecedents of financial satisfaction of individuals from tier II city of India. Financial planners may utilize this study for enhancement of financial satisfaction of their clients and hence retention of the same.

Originality/value
A majority of researchers use survey without evaluation validity of instruments in the selected context and sample. This research contributed to the literature and practice by testing validation of constructs of financial satisfaction in India.
Rituals and routines
Authors: Jouxtel Pascal 
Published: June 2018

Purpose
The terms rituals and routines are often conflated in everyday speech about teams, which betrays a common ontology. Yet these concepts have long been researched in two segregated currents of thought: one stemming from sociology and anthropology, focused on the quality of togetherness and the other from evolutionary economics, focused on market performance. The common ontology is nevertheless present in the processual nature of rituals and routines, the underlying shared reference to the “structure-action-artifact” triad and the statement that both are sources of change as well as stability. This paper aims to assess the pertinence of a joint approach.

Design/methodology/approach
The paper presents a historical and contrasted view on the two concepts. A comprehensive field observation of two teams in mid-term organizational change contexts, focused on collective “doings”, is reported. The tentative “binocular lens” was made of two chosen sets of variables, drawn from the theoretical fields of rituals and organizational routines.

Findings
The distinction between rituals and routines in people’s perception, though largely confused, nonetheless reveals the tension between variable and opposing demands for both change and stability from the team side and from the organization side. Their joint action is effective in enhancing the team’s feelings of confidence and control over its own performance and its future within the organization.

Research limitations/implications
This paper is supported by a comparison of only two teams, leaving room for further empirical research about the effects of endogenous rituality and localized routines on autonomy, efficiency and pride.

Originality/value
This paper offers a new theoretical joint view on the two concepts and explores an endogenous potential for organizational change feeding on emotional and symbolic aspects of team work.
Identification of a missense mutation causing exon skipping in a neurofibromatosis type 1 patient
Authors: Fu Ying , Zhang Jia‐qi , Jiang Chun‐lai , Wang Hui‐yan 
Published: June 2018

AbstractNeurofibromatosis type 1 (NF1), caused by germ line mutations of the NF1 tumor‐suppressor gene, is one of the most common autosomal dominant disorders. Here, we reported a NF1 patient with the mutation NF1 c.4367+1G>C. This sequence change locates at the first nucleotide of NF1 intron 32 within the consensus splice site. Compared with NF1 c.4367G>C predicted to potentially damage the wild‐type donor site at c.4367, the NF1 c.4367+1G>C potentially abolishes this wild‐type donor site by in silico analysis. In vitro minigene assay revealed that the NF1 c.4367+1G>C may cause exon 32 skipping. Our result provides further evidence for its clinical significance of NF1 c.4367+1G>C in clinical practise.
Prolonged growth of infantile hemangioma after pulsed dye laser and oral propranolol treatment
Authors: Kagami Shinji , Kaneko Masahide , Kishi Akiko , Katori Tatsuo 
Published: June 2018

AbstractInfantile hemangiomas are the most common tumor of childhood and undergo rapid growth during early infancy followed by gradual involution. After involution, residual lesions sometimes remain. Oral propranolol usually induces earlier involution and redness reduction of infantile hemangiomas. However, the optimal treatment duration is unknown and infantile hemangiomas sometimes recur after cessation of treatment. We report three Japanese patients with recurrent infantile hemangiomas on their cheek. These patients were a 1‐month‐old female baby with a superficial infantile hemangioma, a 3‐month‐old female baby with a mixed infantile hemangioma and a 4‐month‐old male baby with a mixed infantile hemangioma. Two of them also received pulsed dye laser treatment. They did not reach complete or nearly complete resolution of infantile hemangiomas at week 25. These patients experienced regrowth of their infantile hemangioma after 20 months of age and took propranolol after the age of 24 months. There were no severe adverse effects. Propranolol may not only be therapeutic but also prophylactic. Patients with infantile hemangiomas who have taken oral propranolol should be followed up at least 6 months after cessation of treatment, especially infantile hemangiomas on the cheek, and those with partial response to propranolol may require close attention in prolonged growth.
Numerous plasmacytoid dendritic cell infiltration in HIV‐associated psoriasis relieved only with antiretroviral therapy
Authors: Kuwatsuka Sayaka , Koike Yuta , Asai Misachi , Sato Yukie , Murota Hiroyuki 
Published: June 2018

AbstractThe onset of psoriasis is often seen in HIV infection, called HIV‐associated psoriasis. Although HIV‐associated psoriasis is usually refractory, there are some cases relieved only by antiretroviral therapy. In those cases, the pathogenesis may be formed differently from psoriasis vulgaris. We present the case of a 42‐year‐old Japanese man with HIV‐associated psoriasis. The patient developed a systemic scaly eruption, especially on the soles. Histopathological examination showed typical psoriatic findings and plasma cell infiltration into the dermis. The eruption dramatically remitted with antiretroviral therapy alone, without systemic treatment for psoriasis. In immunohistological findings, few CD4+ cells were seen in the patient's skin. In addition, immunofluorescent staining revealed more BDCA‐2 and CD123 double‐positive plasmacytoid dendritic cell infiltration into the dermis than that of psoriasis vulgaris. We suggest that the immune response to HIV including plasmacytoid dendritic cell infiltration may involve in the development and remission of HIV‐associated psoriasis.
When Many Davids Collaborate with One Goliath: How Inter‐organizational Networks (Fail to) Manage Size Differentials
Authors: Fortwengel Johann , Sydow Jörg 
Published: June 2018

AbstractHow do organizations of vastly different size collaborate in order to achieve a common goal? While this poses less of a problem when the network is orchestrated by a classic lead firm, in networks exhibiting a shared governance mode, where leadership responsibilities are more or less equally distributed, size differentials present a critical management challenge. In this paper, we contribute to the literature on coordination in and of inter‐organizational arrangements by emphasizing the so far largely neglected role of size for managing close collaborative relationships. We study the case of Apprenticeship Network, a network that originally consisted of seven small and medium‐sized enterprises, but which then accepted a very large multinational firm as a new member. By unpacking how the network coordinated its endeavour over time to achieve accountability, predictability and a common understanding as critical conditions for effective coordination, we explore how coordination effectiveness may deteriorate and result in the failure of the collaborative effort. We pay special attention to the role of size in these processes, and we theorize how the strategic front and back‐staging of agreed‐upon rules and norms facilitates the formation, maintenance and deletion of a tie, thus producing important network dynamics.
Planned and Unplanned Hospital Admissions and Their Relationship with Social Factors: Findings from a National, Prospective Study of People Aged 76 Years or Older
Authors: Dahlberg Lena , Agahi Neda , Schön Pär , Lennartsson Carin 
Published: June 2018

ObjectiveTo examine the relationship between social factors and planned and unplanned hospital admissions among older people.Data Sources/Study Setting2011 data from the Swedish Panel Study of Living Conditions of the Oldest Old (SWEOLD) and data from the Swedish National Patient Register until December 31, 2012.Study DesignThe study had a prospective design. Data were analyzed via Cox proportional hazard regressions with variables entered as blocks (social factors, sociodemographic and ability factors, health factors).Data CollectionData were collected via interviews with people aged 76+ (n = 931).Principal FindingsLiving in institutions was negatively associated with planned admissions (hazard ratio (HR): 0.29; confidence interval (CI): 0.09–0.88), while being in receipt of home help was positively associated with unplanned admissions (HR: 1.57; CI: 1.15–2.14). Low levels of social contacts and social activity predicted unplanned admissions in bivariate analyses only. Higher ability to deal with public authorities was positively associated with planned admissions (HR: 1.77; CI: 1.13–2.78) and negatively associated with unplanned admissions, although the latter association was only significant in the bivariate analysis.ConclusionsHospital admissions are not only due to health problems but are also influenced by the social care situation and by the ability to deal with public authorities.
Circulating miR‐338‐5p is a potential diagnostic biomarker in colorectal cancer
Authors: Bilegsaikhan Enkhnaran , Liu Hai Ning , Shen Xi Zhong , Liu Tao Tao 
Published: June 2018

OBJECTIVEThe expression of miR‐338‐5p has been reported to be upregulated in colorectal cancer (CRC) tissues. Clinicopathological features indicate that miR‐338‐5p overexpression correlates with the metastatic status of CRC. This study was aimed to investigate the diagnostic value of serum miR‐338‐5p for CRC.METHODSPeripheral blood samples were collected from 210 participants, including 80 patients with CRC, 50 with colorectal polyps and 80 healthy controls. Serum miR‐338‐5p was quantified by quantitative reverse‐transcription polymerase chain reaction. The area under the receiver operating characteristic curve (AUROC) was used to estimate the diagnostic value of miR‐338‐5p, carcinoembryonic antigen (CEA) and the combination of these two biomarkers.RESULTSSerum miR‐338‐5p levels (fold change) in patients with CRC and colorectal polyps, and controls were 4.94 ± 1.13, 4.12 ± 0.75 and 3.07 ± 0.75, respectively. Significant differences were observed between the groups (P < 0.001). The AUROC of miR‐338‐5p was 0.923 (95% CI 0.882–0.964) and 0.845 (95% CI 0.792–0.898), respectively, for distinguishing CRC from healthy controls or from those without CRC. The AUROC of the combination of miR‐338‐5p and CEA was 0.932 (95% CI 0.882–0.964), with a sensitivity of 85%, a specificity of 88.8% at a cut‐off value of 8.16.CONCLUSIONSCirculating miR‐338‐5p may serve as a potential noninvasive diagnostic biomarker for detecting CRC. The combination of miR‐338‐5p and CEA exhibits the highest diagnostic value in our study.
Clinical Predictors of Acute Brain Injury in Carbon Monoxide Poisoning Patients With Altered Mental Status at Admission to Emergency Department
Authors: Kim Youn‐Jung , Sohn Chang Hwan , Seo Dong Woo , Oh Bum Jin , Lim Kyoung Soo , Kim Won Young 
Published: June 2018

AbstractObjectivesObjective screening tool for patients at a high risk of developing acute brain injury (ABI) is necessary for the proper treatment of carbon monoxide (CO) poisoning patients. The aim of this study is to identify clinical factors that could predict ABI due to CO poisoning in patients with an altered mental status.MethodsA prospectively collected CO poisoning registry at a single academic medical center was retrospectively analyzed. CO poisoning patients with an altered mental status at the emergency department, defined as unalert on the alert/responsive to voice/responsive to pain/unresponsive scale and underwent diffusion‐weighted magnetic resonance imaging (DW‐MRI) between January 1, 2013, and December 31, 2015, were included. ABI was defined as the presence of acute hypoxic brain lesions. Clinical predictors of ABI were identified by multivariate logistic regression analysis.ResultsOf 180 patients, 67 (37.2%) had ABI as revealed by DW‐MRI. Multivariate analysis showed that CO exposure duration > 5 hours (adjusted odds ratio [AOR] = 7.082; 95% confidence interval [CI] = 3.463–15.014; p < 0.001) defined as the time between CO exposure and rescue, abnormal white blood cell count (AOR = 2.568, 95% CI = 1.188–5.700, p = 0.02), and abnormal creatinine concentration (AOR = 2.667, 95% CI = 1.110–6.605, p = 0.03) were predictors of ABI. CO exposure duration had the highest predictive value (area under the curve, 0.815), and the optimal cutoff value was 5 hours. Moreover, increasing exposure durations (quartile) indicated a stepwise increase in the risk of ABI.ConclusionsIn CO poisoning patients with an altered mental status, CO exposure duration was useful for predicting ABI, which may help clinicians or paramedics identify high‐risk patients and provide treatment on priority.
Comparative analysis of the blood transcriptomes between wolves and dogs
Authors: Yang X. , Zhang H. , Shang J. , Liu G. , Xia T. , Zhao C. , Sun G. , Dou H. 
Published: June 2018

SummaryDogs were domesticated by human and originated from wolves. Their evolutionary relationships have attracted much scientific interest due to their genetic affinity but different habitats. To identify the differences between dogs and wolves associated with domestication, we analysed the blood transcriptomes of wolves and dogs by RNA‐Seq. We obtained a total of 30.87 Gb of raw reads from two dogs and three wolves using RNA‐Seq technology. Comparisons of the wolf and dog transcriptomes revealed 524 genes differentially expressed genes between them. We found that some genes related to immune function (DCK, ICAM4, GAPDH and BSG) and aerobic capacity (HBA1, HBA2 and HBB) were more highly expressed in the wolf. Six differentially expressed genes related to the innate immune response (CCL23, TRIM10, DUSP10, RAB27A, CLEC5A and GCH1) were found in the wolf by a Gene Ontology enrichment analysis. Immune system development was also enriched only in the wolf group. The ALAS2, HMBS and FECH genes, shown to be enriched by the Kyoto Encyclopedia of Genes and Genomes analysis, were associated with the higher aerobic capacity and hypoxia endurance of the wolf. The results suggest that the wolf might have greater resistance to pathogens, hypoxia endurance and aerobic capacity than dogs do.
Environmental correlates of livestock depredation by spotted hyaenas and livestock herding practices in a semi‐arid communal landscape
Authors: Mbiba Monicah , Muvengwi Justice , Ndaimani Henry 
Published: June 2018

AbstractHuman population increase, expansion of anthropogenic activities and the subsequent decline of wildlife habitats have resulted in constant overlaps in the needs of people and wildlife, resulting in human–wildlife conflict. One of the key drivers of human–wildlife conflict is livestock depredation by carnivores. Most studies on human–wildlife conflict have been conducted in communal areas adjacent to protected areas; however, little has been done in communities far from protected areas. To understand the environmental correlates of livestock depredation events in a communal landscape far from protected areas, we used maximum entropy modelling to predict occurrence of spotted hyaena (Crocuta crocuta) kill sites using distance from hills, homesteads, roads and tracks, streams and normalized difference vegetation index (NDVI). In addition, we investigated the livestock herding and kraaling practices of rural households in Nyamandi Communal Area, Zimbabwe. Distance to nearest homestead was the most important environmental correlate of kill site occurrence (85.8%), as more kills occurred nearer to homesteads. More households herded livestock in the wet than in the dry season, but interestingly, significantly more attacks occurred in the wet season than in the dry season (p < 0.05). We conclude that distance from homesteads is the most important correlate in the prediction of livestock depredation in this communal landscape.
Two and a half years on: data and experiences establishing a ‘Virtual Clinic’ for joint replacement follow up
Authors: Lovelock Thomas , O'Brien Michael , Young Ian , Broughton Nigel 
Published: June 2018

BackgroundWe use a ‘Virtual Clinic’ for follow up of hip and knee replacement patients. The aim of this study was to investigate patient compliance, pain and function, revision rates and surgeon experience using this system.MethodsAll hip and knee replacements conducted from 2000 onwards were suitable for ‘Virtual Clinic’ review. Between July 2014 and December 2016, all patients due for follow up (at 1, 5 and 7 years post‐operatively, or biennially thereafter) were mailed an Oxford Hip or Knee Score and a request for a radiograph. A surgeon reviewed the questionnaire and radiograph and decided whether face‐to‐face review was necessary. We calculated compliance as the percentage of eligible patients who completed the ‘Virtual Clinic’. We used retrospective review of medical records for all clinic participants to analyse Oxford scores, disposition following appointment, and revision rates. We reviewed all clinic participants in December 2017 to identify any further revisions. Surgeon feedback was assessed by emailed survey.ResultsA total of 2076 patients were due for follow up. 1405 patients were contactable, and 710 completed the process. We calculated a 36% compliance rate. Surgeons decided 162 (23%) patients with a mean Oxford score of 24.2 required face‐to‐face assessment. This identified 13 patients needing revision. One other patient was revised for loosening which developed between ‘Virtual Clinic’ appointments. Surgeon feedback indicated the inclusion of a ‘comment’ section on the questionnaire as particularly useful.DiscussionWe describe our adoption of a ‘Virtual Clinic’ for joint replacement follow up. We recommend this system as a practical method of following up patients.
Soil seed bank assay methods influence interpretation of non‐native plant management
Authors: Chiquoine Lindsay P. , Abella Scott R. 
Published: June 2018

AbstractQuestionsIn the assessment of a soil seed bank at invaded sites, do sampling at different microsite types and use of different assessment methods yield different results, which may influence interpretation of management effectiveness and potential for native plant restoration?LocationSaguaro National Park, Arizona, United States.MethodsSeed bank samples were collected from two microsite types (below‐shrub canopies and interspaces between perennial plants) at plots within Pennisetum ciliare‐invaded and untreated sites, non‐invaded sites and sites with five frequencies of Pennisetum‐removal treatments. Seed bank samples were characterized by seedling emergence and seed extraction methods.ResultsAssay method influenced whether we detected a significant Pennisetum‐removal treatment response on Pennisetum detected in the seed bank. A treatment response was not observed using the emergence method. Using the extraction method, we found that untreated Pennisetum plots contained significantly more Pennisetum seed than removal treatments. Treatments did not affect detection of native seed banks using either method. Microsite type only had an effect on seed detected using the emergence method, where more perennial species and seed densities were detected below shrubs. Native species richness and estimated seed densities using extraction were correlated with emergence results (r = 0.52, N = 42, p < 0.001 and r = 0.56; N = 42, p < 0.001, respectively).ConclusionsResults highlight several considerations for how different seed bank methods can influence interpretation of management treatments. Along with vegetation surveys, seed bank observations indicate that removal treatments successfully reduced Pennisetum in soil seed banks at invaded sites relative to invaded untreated sites. Natives were a significant proportion of seed banks, showing potential for native plants to establish after treatments of non‐native plants. Results suggest potential to calibrate seed bank methods with each other to reconcile differences. Because viability of extracted seed was uncertain, further analysis may be necessary to test which assay method best predicts future vegetation.
MicroRNA‐351‐5p aggravates intestinal ischaemia/reperfusion injury through the targeting of MAPK13 and Sirtuin‐6
Authors: Hu Yupeng , Tao Xufeng , Han Xu , Xu Lina , Yin Lianhong , Sun Huijun , Qi Yan , Xu Youwei , Peng Jinyong 
Published: June 2018

Background and PurposeIntestinal ischaemia‐reperfusion (II/R) injury is a serious clinical problem. Here we have investigated novel mechanisms and new drug targets in II/R injury by searching for microRNAs regulating such injury.Experimental ApproachWe used hypoxia/reoxygenation (H/R) of IEC‐6 cell cultures and models of II/R models in rats and mice. Microarray assays were used to identify target miRNAs from rat intestinal. Real‐time PCR, Western blot and dual luciferase reporter assays, and agomir and antagomir in vitro and in vivo were used to assess the effects of the target miRNA on II/R injury.Key ResultsThe miR‐351‐5p was differentially expressed in our models and it targeted MAPK13 and sirtuin‐6. This miRNA reduced levels of sirtuin‐6 and AMP‐activated protein kinase phosphorylation, and activated forkhead box O3 (FoxO3α) phosphorylation to cause oxidative stress. Also, miR‐351‐5p markedly reduced MAPK13 level, activated polycystic kidney disease 1/NF‐κB signal and increased NF‐κB (p65). Moreover, miR‐351‐5p up‐regulated levels of Bcl2‐associated X, cytochrome c, apoptotic peptidase activating factor 1, cleaved‐caspase 3 and cleaved‐caspase 9 by reducing sirtuin‐6 levels to promote apoptosis. In addition, miR‐351‐5p mimic in IEC‐6 cells and agomir in mice aggravated these effects, and miR‐351‐5p inhibitor and antagomir in mice alleviated these actions.Conclusions and ImplicationsOur data showed that miR‐351‐5p aggravated II/R injury by promoting intestinal mucosal oxidative stress, inflammation and apoptosis by targeting MAPK13 and sirtuin‐6.These data provide new insights into the mechanisms regulating II/R injury, and of miR‐351‐5p could be considered as a novel therapeutic target for such injury.