bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of the characteristics of terminal ileal ulcers: prognosis and clinical significance
Authors: Yang Liping , Zhang Zhongchen , Zhou Xinxin , Chen Chunxiao 
Published: July 2019

Abstract
Background
Although terminal ileal ulcers can be observed occasionally in colonoscopy examination, the prognosis, clinical significance and treatment guidelines are unclear.
Methods
All patients diagnosed with terminal ileal ulcers from March 2014 to March 2018 were enrolled. We extracted data of gender, age, clinical symptoms, number of terminal ileal ulcers, pathological outcome, treatment programs.
Results
Of 42 individuals, one patient diagnosed with tuberculosis and received anti-tuberculosis treatment. The other 41 individuals chose to follow up or 5-ASA plus probiotics treatment. Logistic regression analysis showed no significant difference in treatment selection and gender (P=0.848), age (P=0.481), ulcers (p=0.116), symptoms (P=0.326). All individuals had good prognosis.
Conclusion
Individuals with terminal ileal ulcers have a good prognosis regardless of follow-up or treatment.
A Survey on Mental Health Status and Related Factors among Cancer Patients in Iran
Authors: taheri masood , afshari mahnaz , alidoost saeede , gorji hassan abolghasem , rakhshan amir 
Published: July 2019

Abstract
Background: Cancer is one of the most common non-communicable diseases and the second cause of death in Iran. The progress in medical technologies and treatment plans has caused the patients to live longer; however, these patients are confronted with psychological challenges and their mental health is influenced because of different reasons. This study is carried out to investigate the mental health status of the cancer patients in the Center for Specific Diseases.
Methods: The present research is a cross-sectional, descriptive, and analytic study carried out in 2018 in Tehran province, Iran. In the present study, the mental health of the cancer patients referring to the Center for Specific Diseases in Tehran was evaluated in one setting, and no intervention was provided. The research population included 124 cancer patients of Tehran referring to the Center for Specific Diseases.
Results: the overall prevalence of psychiatric disorders in patients under study was 50%. The highest sensitivity to mental disorders in each of the variables was related to men (52.7%), patients aging 40-55 (45.7%), married (51.5%), unemployed (62.5%), and illiterate patients (80%). The findings of this study indicated that there is no statistically significant relationship between the prevalence of psychiatric disorders among patients with cancer and the variables in the study.
Conclusions: The results of this study indicated a high prevalence of depression disorder among cancer patients. Psychosocial stresses caused by cancer cause mental disorders, including depression in patients.
Clinical characteristics and prognostic factors in elderly patients with metastatic pancreatic cancer: a population-based study
Authors: Lianyuan Tao , Haibo Yu , Yadong Dong , Guanjing Tian , Zhiyuan Ren , Li Deyu 
Published: July 2019

Abstract
Background: The aim of this study was to evaluate the prognostic factors of elderly patients with metastatic pancreatic cancer (mPC).
Methods: Patients diagnosed with mPC between2004 and2014 were identified from the Surveillance Epidemiology and End Results (SEER) database. Clinical characteristics and prognostic factors in elderly patients with mPC were examined.
Results: A total of 10784 mPC patients between 65 and 80 years old were included and divided into three age groups. Elderly mPC patients differed from younger patients in many aspects, including marital status, race, gender, T stage, N stage, treatment regimen, prognosis, cause of death, and metastatic characteristics (p<0.001). An analysis of the prognostic factors showed that chemotherapy, as the main treatment for the elderly, can significantly improve their prognosis, while surgery can improve the prognosis of patients between 65 and 80 years old. Other factors, including gender, marital status, T stage, and site of metastasis, had different effects on patients in different age groups.
Conclusion: Elderly patients with mPC are a special group of individuals whose clinical characteristics and prognostic factors are different from those of younger patients and require special treatment and attention.
First report of Mesocriconema xenoplax (Nematoda: Criconematidae) from turfgrass in Portugal and in Europe
Authors: Inácio M. L. , Rusinque L. C. , Camacho M. J. , Nóbrega F. 
Published: July 2019

Abstract
In Winter 2016, root and soil samples were collected from the rhizosphere soil at 10 to 15 cm depth of turfgrass, in the yard of a complex of houses in Caxias, a region near Lisbon, Portugal. The grass (dominated by tall fescue) showed yellow patches, stunting, and poor growth. Several specimens of a ring nematode (50-60 nematodes/100 ml soil) were recovered from soil and identified as Mesocriconema xenoplax (peach ring nematode) based on morphological and morphometrical analysis of females. The observed morphological features were with previous descriptions. Species identification was confirmed through sequencing of the fragment spanning D2/D3 domain of the 28S rDNA gene. Phylogenetic analysis revealed that the Portuguese isolate grouped with M. xenoplax isolates (98% similarity), supporting its identification as M. xenoplax. This is the first report of M. xenoplax from turfgrass in Portugal and in Europe contributing with additional information on the distribution of this phytoparasite.
Nexus between sanitation and groundwater quality: case study from a hard rock region in India
Authors: Bhallamudi S. Murty , Kaviyarasan R. , Abilarasu A. , Philip Ligy 
Published: July 2019

Abstract
Groundwater quality in the towns of Namakkal and Erumaipatti in India was studied to understand the nexus between surface sanitation and groundwater quality in hard rock regions. In total, 32 wells, both shallow open and deep bore wells, were monitored over a two-year period. The presence of fecal coliforms (FCs) up to 600 CFU/100 mL in wells as deep as 100 m showed that bacteriological contamination had reached deep aquifers through fractures and fissures. Statistical analyses showed that bore wells located in Namakkal were bacteriologically more contaminated than those in Erumaipatti (p = 0.017 for FC) because of urbanization, the type of top soil and the shallow groundwater table. Wells in densely toileted areas of Namakkal were more contaminated than those located in open defecation areas. After replacing a soak pit with a septic tank, concentrations of FC and chemical oxygen demand (COD) in the leachate at a depth of 2.1 m reduced from 2,500 to 1,000 CFU/100 mL and from 200 to 50 mg/L, respectively, after 150 days of the construction of septic tanks. To improve the hygiene and sanitation, the provision of toilets along with on-site waste management systems, capable of achieving required effluent quality, are essential.
ADMINISTRANDO O "CORPO ARCO ÍRIS"
Authors: Coelho Júnior Carlos Lacerda , Ratts Júnior 
Published: July 2019

O artigo tem por objetivo analisar de que forma a pastoral do sexo se constitui, entre seus adeptos, em três denominações cristãs inclusivas, a saber, Igreja Missionária Inclusiva (IMI), situada em Maceió (Alagoas) e as congregações Igreja Apostólica Filhos da Luz (IAFL) e Cidade de Refúgio, ambas localizadas na cidade de Fortaleza (Ceará). Além do mais, apresenta-se um breve esboço das trajetórias acadêmicas construídas pelos autores desse texto no tocante as escolhas dos seus respectivos objetos e os impactos subjetivos vivenciados durante e após a pesquisa de campo.
Palavras-chave: Estudos de gênero. Teoria Queer. Igrejas Inclusivas. Cristianismo
DO SINGULAR AO COMUM?
Authors: Bueno Arthur 
Published: July 2019

Sobre o pano de fundo dos debates recentes acerca de um “novo individualismo”, este artigo procede a uma reconstrução sistemática de três oposições homólogas apresentadas na obra de Simmel: uma, mais notória, entre individualismo quantitativo e qualitativo; outra, central para o projeto da Sociologia de 1908, entre aspectos sociais e extrassociais do indivíduo; e aquela, articulada em seus escritos tardios, entre individualismo românico e germânico. Esses dualismos ganham um novo sentido quando encarados do ponto de vista de um conflito entre duas tendências: uma, individualista, na direção do estabelecimento de fronteiras nítidas entre o eu e o mundo e da consideração de cada ser humano como uma entidade autocentrada; outra, in-dividualista, no sentido da promoção de experiências de permeabilidade do eu emrelação ao mundo e constituição de uma vida qualitativamente comum. Isso tem consequências importantes para uma reavaliação do diagnóstico simmeliano da cultura moderna. Se é verdade que em seus escritos a modernidade é com frequência descrita como uma época marcada pela acentuação de certos tipos de in-dividualidade, a interpretação aqui proposta permite ressaltar, por outro lado, como diferentes figuras da in-dividualidade emergiram historicamente em conexão com – e em reação a – esse processo. Reconstruídosdessa perspectiva, os argumentos de Simmel fornecem subsídios para uma reconsideração das análises sociológicas a respeito da institucionalização, nas últimas décadas, de um “novo individualismo” cujas origens remontariam à tradição romântica e ao modernismo estético. Eles permitem identificar em tais correntes não apenas uma acentuação da singularidade autossuficiente do indivíduo, mas também – sob a forma de um potencial restringido – o horizonte de uma vida comum.
Palavras-chave: novo individualismo. Singularidade. Vida comum. Formas de sociação. Modernidade.
QUALIDADE DO PARTO E IMPACTO NOS INDICADORES DA SAÚDE DA CRIANÇA
Authors: Araújo Isabelle Christine Fonsêca Gomes de , Ferreira Tainara Lorena dos Santos , Araújo Daísy Vieira de , Melo Káthya Daniella Figueiredo , Andrade Fábia Barbosa de 
Published: July 2019

Introdução: A qualidade da assistência do parto indica um importante fator nas taxas de mortalidade infantil, pois os problemas decorrentes deste, quando realizado de forma inadequada, pode ter repercussão sobre o recém-nascido durante os primeiros dias de vida. Objetivo: Avaliar a qualidade da assistência do parto e a correlação com os indicadores de saúde da criança. Método: Trata-se de um estudo quantitativo e avaliativo dos indicadores de morbidade e mortalidade materno e infantil realizado nas Unidades Básicas de Saúde que integram a rede da Atenção Primária à Saúde (APS), do município de Santa Cruz, Rio Grande do Norte, Brasil. Com uma amostra de 200 mulheres mães de crianças menores de dois anos. Resultados: Foram entrevistadas mães com média de idade de 28,17 anos, com bebês com em média 10,42 meses de idade. 95,5% das mães afirmaram ter realizado o acompanhamento pré-natal. A maioria (60,5%) das mulheres classificou a assistência recebida no parto como boa; 74,5 % afirmaram que a criança foi colocada no peito após o parto; 90% dos binômios mãe-bebê estiverem juntos no quarto após o parto. Conclusões: Pode-se perceber que a assistência ao parto acontece de forma adequada e satisfatória, atendendo necessidades da maioria das entrevistadas. Porém ainda há uma necessidade de conscientização e qualificação dos profissionais de saúde, para que não ocorram situações indesejáveis na saúde materno-infantil e diminua as taxas de morbidade e mortalidade materna e neonatal.
Withdrawn: Synthesis Characterization of Mannich Base Products Using Higher Alkyl Substituted 1,2,4-Triazolium Methane Sulfonate Based Bronsted Acidic Ionic Liquids as Catalyst
Authors: Veeraragavan Vijayakumar , Sankaranarayanan Nagarajan , Chidambaram Ramesh Kumar 
Published: July 2019

The article has been withdrawn on the request of the authors and the editor of the journal "Current Organic Synthesis."

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Persistent Respiratory Distress in the Term Neonate: Genetic Surfactant Deficiency Diseases
Authors: Magnani Jessie E. , Donn Steven M. 
Published: July 2019

:
Respiratory distress is one of the most common clinical presentations in newborns requiring
admission to a Neonatal Intensive Care Unit (NICU). Many of these infants develop respiratory
distress secondary to surfactant deficiency, which causes an interstitial lung disease that can
occur in both preterm and term infants. Pulmonary surfactant is a protein and lipid mixture made
by type II alveolar cells, which reduces alveolar surface tension and prevents atelectasis.

:
The etiology of surfactant deficiency in preterm infants is pulmonary immaturity and inadequate
production. Term infants may develop respiratory insufficiency secondary to inadequate surfactant,
either from exposure to factors that delay surfactant synthesis (such as maternal diabetes) or from
dysfunctional surfactant arising from a genetic mutation.

:
The genetics of surfactant deficiencies are very complex. Some mutations are lethal in the neonatal
period, while others cause a wide range of illness severity from infancy to adulthood. Genes that
have been implicated in surfactant deficiency include SFTPA1, SFTPA2, SFTPB, SFTPC, and
SFTPD (which encode for surfactant proteins A, B, C, and D, respectively); ABCA3 (crucial for
surfactant packaging and secretion); and NKX2 (a transcription factor that regulates the expression
of the surfactant proteins in lung tissue).

:
This article discusses the interplay between the genotypes and phenotypes of newborns with surfactant
deficiency to assist clinicians in determining which patients warrant a genetic evaluation.
Effect of Estrogen Receptor- Alpha Gene Polymorphism (IVS1-397 T>C) on Microvascular Complications of Type 1 Diabetes Mellitus
Authors: Toaima Dalia N. , El-Samahy Mona H. , Zaki Osama K. , Elshami Yousef M. , Toaima Nadin N. 
Published: July 2019

Background::Type 1 diabetes mellitus (T1DM) is an autoimmune disease whose etiology involves genetic predisposition as well as environmental factors. Polymorphisms of some genes are among the most important genetic factors that influence autoimmunity. Gender is another important factor affecting autoimmunity. Females are more susceptible to autoimmune diseases which may be due to the effect of sex hormones on the immune system activity. The metabolic effects of estrogen are mediated through its receptor – alpha. The exact mechanism is not well understood. A number of polymorphisms have been reported in the Estrogen Receptor- alpha (ER-alpha) IVS1 397 T>C gene which may be involved in the pathogenesis of diabetes.Objectives::To assess the influence of Estrogen Receptor- alpha gene [IVS1-397 T>C] polymorphism on vascular complications of type1 diabetes mellitus in pubertal females and on the glycemic control.Methods::This cross-sectional case-control study included 40 pubertal regularly menstruating girls less than 18 years with type 1 diabetes mellitus recruited from the Pediatric Diabetes Clinic, Childrenʼs Hospital, Ain-Shams University and 20 healthy age-and sex-matched controls. Estrogen receptor alpha genotypes were analyzed by Restriction Fragment Length PCR and correlated with both clinical and laboratory parameters in the studied cases. ER-alpha was chosen as it might play a role in diabetes pathogenesis.Results::The study revealed the TC genotype was the most prevalent genotype of the estrogen receptor. The TT genotype patients had a younger age of onset of T1DM. The prevalence of obesity was higher among TC and TT than in CC bearing patients. In addition, CC genotype patients had the least prevalence of microalbuminuria and had better glycemic control than other genotypes.Conclusion::Our findings suggest that Estrogen receptor- alpha gene may be affecting the age of onset of Type1 diabetes mellitus in pubertal girls as well as the glycemic control of these patients, where CC bearing girls had better glycemic control than other genotypes and less incidence of microalbuminuria.
Study of interactions energies between residues of the active site of Hsp90 and the geldanamycin analogues using Quantum Mechanics/Molecular Mechanics (QM/MM) methods
Authors: Vivas-Reyes Ricardo , Morales-Bayuelo Alejandro , Gueto Carlos , Droso Juan C. , Márquez Johana , Baldiris Rosa , Ahumedo Maicol , Vivas-Gomez Catalina , Aparicio Dilia 
Published: July 2019

Background:
(Hsp90) 90KDa heat shock proteins are molecular chaperone involved in process of cellular oncogenesis, hence its marked importance as a therapeutic target. An inhibitor of Hsp90 chaperone activity is the geldanamycin, a thready compound that has the power to bind to the binding of ATP in the N-terminal of Hsp90 domain site, however this reported in clinical trials hepatotoxic damage, which I pitting to its disuse. On the other hand, taking advantage that the geldanamycin joins successfully Hsp90, efforts have focused on the search for similar that they have the same or better effect and both exhibited lower effects than its predecessor, as it has been the case with the similar 17-AAG and 17-DMAG.

Methods:
In order to know the chemical factors influencing the growth or decay of the biological activity of such compounds have been evaluated different computational techniques such as docking and 3DQSAR, however it has not been considered in a quantitative way what happens within the active site represented in terms of interaction energy, as it has been evaluated in this work.

Results:
To evaluate interaction energies found that the Lys58 is essential for the union of the analogs to the active site of Hsp90, and that the activity of these will depend on if these have on the C-11 position of the macrocycle a group of small and at the same time attractor of electrons, as it is reflected with the series C-11 hydroxy and methoxy C-11.

Conclusion:
Theses outcomes were supported with Quantum Similarity and reactivity indices using the Density Funtional Theory in order to understand the non-covalent stabilization in the active site for theses compounds.
Optimization of Head Space Pressure Using Liquid Nitrogen in Hot-packed BBQ Sauce
Authors: Yerramsetti Praveen , Bowser Timothy , Ramanathan Ranjith 
Published: July 2019

Introduction:
BBQ sauce was hot-filled at 54°C (130°F) in plastic PET, 567 g (20 oz) bottles. The PET bottles paneled, due to the temperature and pressure of the hot-fill process. Liquid nitrogen was used as a processing aid to optimize the headspace pressure to prevent paneling.

Objective:
The objective of the research was to eliminate paneling of the PET bottles due to hot-filling.

Methods:
A micro dosing system was used to inject nitrogen into the container just after filling and immediately prior to capping. Headspace pressure was measured using a custom-designed pressure sensor. Nitrogen dosage time was plotted against headspace pressure. The relationship between nitrogen dosage time and headspace pressure was linear, with a coefficient of determination of 0.84, and slope of 1.36 kPa/ms, with an intercept of -12.21 kPa.

Results & Conclusion:
Results were analyzed using analysis of variance. Visual inspection of the bottles for defects resulted in the determination of the optimum headspace pressure of 30 kPa (4.4 psi).
PEMODELAN SEBARAN BOD DI SUNGAI KAPUAS KECIL BAGIAN HILIR MENGGUNAKAN WASP
Authors: Purnaini Rizki , Sudarmadji Sudarmadji , Purwono Suryo 
Published: July 2019

The Kapuas Kecil River must be maintained for its water quality so that it can still be utilized in accordance with its designation. The purpose of this study is to predict water quality changes due to incoming waste from various sources of pollutants to the concentration of BOD in Kapuas Kecil River using WASP model as an effort to water quality monitoring and water pollution control.The study area to be simulated is Kapuas Kecil River passing through Pontianak City over ± 22 km from upstream to downstream (estuary) that divided into 42 segments. Water quality data were collected from several monitoring station locations in Kapuas Kecil River downstream, Landak River, effluent trenches located within the administrative area of Pontianak City, as well as secondary data on industrial effluents located along the study area. Water sampling method refers to the SNI 03-7026-2004, sampling was done once at each sample point with variations of the rainy and dry season, and at high and low tide conditions. Hydrometry data and river discharge can be obtained from primary and secondary data.The results showed that domestic and non-domestic of urban discharges that entering the river is very dominant influence on the water quality of the river. BOD concentration in rivers during the dry season is higher than rainy season both in high and low tide conditions. The simulation results of spatial distribution with all scenarios show that the accumulation of BOD pollution load begins after a distance of 5 km from the upstream boundary and then a significant increase in concentration occur at segment 27 with loads originating from the Landak River and Pekong Trench. The BOD concentration then tends to fluctuate to a distance of 5 km before heading downstream, and after that it continues to decline towards the downstream.
BUSINESS FEASIBILITY AND STRATEGY OF BUSINESS DEVELOPMENT OF CATFISH HATCHERY IN MINAPOLITAN AREA OF MAGELANG DISTRICT
Authors: Tri Cahyono Riyadi , Suryantini Any , Mulyo Jangkung Handoyo 
Published: July 2019

This study aims to (1) identify the feasibility of catfish hatchery business and (2) to know the alternative and strategic priorities that can be applied in the development of catfish hatchery business in the Minapolitan Area of Magelang District. Research location in sub-District of Muntilan, Mungkid, and Sawangan, was chosen by purposive sampling. Respondents were chosen by snowball 42 as samples from farmers and stakeholders related to catfish hatchery business. Data analysis used on the business feasibility is BEP and R/C ratio criteria. The analysis of business development strategy uses SWOT analysis. The business feasibility analysis tool used is cost analysis, revenue, and nett revenue. Feasibility analysis result obtained BEP revenue of Rp53.587.484,00, BEP production of 255.087,71 unit fish, BEP price of Rp 56.00 per unit fish, and R/C ratio of 1,67. The development of strategy of catfish hatchery business are (1) maintaining good relationship with stakeholders and maximizing natural resources management for business development due to low interest of community on catfish hatchery business, and (2) utilizing expert resources (practitioners and academics) in the field of hatchery by government assistance to improve the quality of seed products and for expanding market size to meet the increased demand.