bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative effectiveness from a single-arm trial and real-world data: alectinib versus ceritinib
Authors: Davies Jessica , Martinec Michael , Delmar Paul , Coudert Mathieu , Bordogna Walter , Golding Sophie , Martina Reynaldo , Crane Gracy 
Published: June 2018

Aim:
To compare the overall survival of
anaplastic lymphoma kinase
-positive non-small-cell lung cancer patients who received alectinib with those who received ceritinib.
Materials & methods:
Two treatment arms (alectinib [n = 183] and ceritinib [n = 67]) were extracted from clinical trials and an electronic health record database, respectively. Propensity scores were applied to balance baseline characteristics. Kaplan–Meier and multivariate Cox regression were conducted.
Results:
After propensity score adjustment, baseline characteristics were balanced. Alectinib had a prolonged median overall survival (alectinib = 24.3 months and ceritinib = 15.6 months) and lower risk of death (hazard ratio: 0.65; 95% CI: 0.48–0.88).
Conclusion:
Alectinib was associated with prolonged overall survival versus ceritinib, which is consistent with efficacy evidence from clinical trials.
Exposition of process-based learning for first year university students
Authors: Callary Bettina , Maher Patrick , Root Emily , Ryan Jennifer 
Published: June 2018

In this expository essay, four faculty members co-reflect on the pedagogy used within one first-year course, Introduction to Community Studies (COMS 1100) at Cape Breton University (CBU). We discuss the responsibility of facilitating five process-based pedagogical approaches. These complex and interrelated processes include: i) self -directed learning, ii) reflexive intra-personal learning, iii) group/inter-personal development, iv) experiential learning, and v) community-based and/or service learning. We describe and give examples of how these approaches help students learn how to learn, function, and grow respectfully with one another and with community.
Challenges and Successes: Faculty Reflections on a College Teaching Development Program
Authors: Jeppesen Alison , Joyce Brenda 
Published: June 2018

Does participation in a reflective teaching development program transform educators? In a three-year teaching development program, faculty met in small interdisciplinary groups with peer facilitators and used online resources to complement their learning activities. The first two cohorts of participants found that involvement in a teaching development program encouraged them to develop self-reflective practices that they viewed as positively impacting their teaching. While valuing the collaborative and collegial relationships created through program participation as these supported their individual growth and development, faculty also identified challenges that created barriers to their participation in the program.
Managing the transition from concussion to return to learn in postsecondary education: strategies based on principles of UDL
Authors: Frost Gail , Connolly Maureen 
Published: June 2018

Concussion is a functional brain injury that can produce physical, cognitive, emotional and sleep-related symptoms. With correct management, most symptoms will resolve within a month and a gradual, progressive return to activity (cognitive and physical) that allows students to stay below the thresholds that make symptoms worse, can be started after the immediate post-impact rest period of 24-48 hours. The 6-step Return-to-Learn protocol works well to manage the return to the classroom for elementary and high school-aged students, however it is difficult to implement in a postsecondary setting, as it requires a level of monitoring not generally available through college or university student wellness centres. As a result, course instructors are often given the task of providing accommodations to help students recovering from concussion manage and master the content and complete the required work to pass their course. This paper will discuss the challenges facing the postsecondary student recovering from concussion and provide accommodation ideas and examples, with resources, that instructors may find helpful.
Exploring the Foundations for Student Success: A SoTL Journey
Authors: Lockhart Wallace , Wuetherick Brad , Joorisity Nola 
Published: June 2018

This paper illustrates the chronology of a research project which began in 2010 and continues today. The research has evolved over time from a focus on the phenomenon (developing an understanding of student diversity and its impacts on student success), to experimental research (to learn the impact or benefits derived from the introduction of high impact practices), to a more complex understanding of the foundations for student success. The fourth stage of the research, which is just underway, divides our efforts into two distinct directions. The first is quantitative research utilizing institutional and learning management system data which was previously untracked and untapped. The second is a shift to employing more qualitative research tools aimed at advocacy and institutional change. Through each phase of the research the paper presents two distinct perspectives: First is the perspective of instructors-turned-SoTL-researchers as we muddle our way through understanding our challenges and learning how to use SoTL research methods to help guide the way. The second perspective is that of an established SoTL researcher, who provides commentary and guidance to our journey. Our hope is that the reader finds these two perspectives of a research journey both informative and valuable in providing insights into how a long-term research project might unfold.
Evolução do emprego público no Reino Unido: o papel das privatizações/nacionalizações e das políticas sociais desde a Segunda Revolução Industrial até os tempos atuais
Authors: Mattos Fernando Augusto Mansor de 
Published: June 2018

Este artigo analisa a evolução da quantidade e do perfil do emprego público no Reino Unido desde a época da Segunda Revolução Industrial até o presente. Os indicadores de emprego público no Reino Unido mostram que, em diferentes períodos históricos, os processos de constituição de empresas públicas ou de nacionalização ou privatização das empresas públicas já existentes, assim como a constituição e ampliação de políticas sociais estiveram entre os principais fatores que provocaram aumento do emprego público no país. Na seção final do artigo, procura-se avaliar como a recente crise econômica tem afetado o estoque e o perfil do emprego público no Reino Unido.
O CONHECIMENTO DISCIPLINAR DOCENTE PARA ENSINAR CIÊNCIAS NATURAIS: REFLEXÕES PARA A FORMAÇÃO INICIAL DE PROFESSORES
Authors: Núñez Isauro Beltrán , Ramalho Betania Leite 
Published: June 2018

O conhecimento do conteúdo a se ensinar é considerado relevante na constituição da profissionalização da docência. Ele é a maior competência do professor. Por isso, diversos estudos têm abordado os conhecimentos profissionais dos professores para ensinar ciências enfatizando o Conhecimento Pedagógico do Conteúdo, e o conhecimento disciplinar tem sido menos estudado. Neste artigo, apresenta-se uma reflexão sobre o conhecimento profissional disciplinar, com foco em sua natureza e em sua dimensão e se mostra que, como às vezes se supõe, ele não se configura apenas no corpo teórico. Esta reflexão pode contribuir para que se repense a formação inicial dos professores de ciências, na perspectiva da profissionalização da docência.Palavras-chave: Conhecimento profissional. Conhecimento disciplinar. Profissionalização docente.
MEMÓRIAS EDUCACIONAL E POLÍTICA DE UMA PROFESSORA DO RIO GRANDE DO NORTE (1978-2008)
Authors: Fernandes Jessica Luana , Sena Fabiana 
Published: June 2018

Este estudo pretendeu dar visibilidade às memórias de uma professora do Rio Grande do Norte, Valdilene Verônica de Albuquerque Lobo e analisar sua trajetória educacional e seu engajamento político e social na cidade de Pau dos Ferros – RN, entre os anos de 1978 e 2008. O interesse pela história dessa professora surgiu porque, quando tomamos conhecimento da trajetória de mulheres educadoras engajadas politicamente nos movimentos sindicais e sociais de Pau dos Ferros, nossa curiosidade nos fez questionar sobre a representatividade feminina na política dessa cidade. Para compreender o processo de construção da identidade professoral de Valdilene Verônica de Albuquerque Lobo, utilizamos fontes orais (história oral), para que ela narrasse seu processo de escolarização formal articulado entre histórias familiares e configurações políticas. Assim, neste estudo, não atentamos para a professora e seus eventos narrados como um retrato fiel do passado, porquanto a memória é algo mutável e ressignificada a partir do olhar do presente. Palavras-chave: Memória. Docência. Política.
Efficacy of Rehabilitation Measures on the Functional Development of Children with Spastic Cerebral Palsy
Authors: A Dinakaran 
Published: June 2018

Background: Spastic cerebral palsy (CP) is the most common type of CP. Up to 80% of all Individuals with cerebral palsy suffer from some degree of spasticity. Spasticity adversely affects muscles and joints of the extremities, causing abnormal movements, and it is especially harmful in growing children.
Cerebral palsy (CP) is a syndrome of motor impairment that results from a lesion occurring in the developing brain. The degree of spasticity can vary from mild muscle stiffness to severe, painful, and uncontrollable muscle spasms .Normally; muscles must have enough tone to maintain posture or movement against the force of gravity while at the same time providing flexibility and speed of movement.
Spasticity is a velocity-dependent increase in resistance of a muscle when the muscle is moved passively or stretched. Individuals with spastic CP experience stiffness in affected limbs due to focal muscular hyperactivity, resulting in limited or awkward movements.
In this research work Quasi experimental design was adopted for Pre- assessment of physical and functional status of children with cerebral palsy assessed by appropriate tools and the results discussed in detailed in different sections of the paper.
Bibliografía de filología hispánica
Authors: De Filología Hispánica Nueva Revista 
Published: June 2018

Las reseñas se consignan a continuación del libro (o artículo reseñado). Cuando éste se ha descrito en una entrega anterior de la Bibliografía, se pone entre paréntesis el número de ficha correspondiente. También se hacen referencias a ediciones anteriores de una obra, a tomos anteriores de una obra en curso de publicación, etc. En estos casos, la cifra que precede al número de referencia indica el volumen de la NRFH en que figura la ficha en cuestión. Así, el "núm. 39-39695" corresponde a la ficha 39695, la cual está en el volumen 39 de la NRFH. Cuando no hay cifra inicial, ha de entenderse que el número remite a una ficha incluida en el presente fascículo.
How Much is an Image Worth?
Authors: BAZAC Ana 
Published: June 2018

The paper discusses the problem of “competition” between the image and the articulated language/text. The problem as such is historical and it reflects the change between the language based communication (including the radio era) and the mainly image based communication. Opposing to those who equate the image construction in the information and communication technology with the impoverishment of meanings and necessity and ability of logical/rational discourse, the arguments of these two positions are analysed. The paper mentions the difference between representation, image and idea, analyses some arguments related to the logical articulation of words in texts, and to the specific imagistic manner of communication, and concludes that the text and image are complimentary, and that their worth depends on the meanings they transmit and the quality of meanings/values they transmit. In this respect, the diminishing of preoccupations, of ability and time for logical articulation of the reference to the world means the decline of man. At the same time, the theory highlighted in the paper does not counter the “bad” image to the “good” text (and certainly, nor vice versa), but the measure in their use according to the scale of goals and means which people must have.
Evaluación del estado nutricional de adolescentes en una Unidad Educativa de Ecuador. // Evaluation of the nutritional status of adolescents in an Educational Unit of Ecuador.
Authors: Sánchez-Mata Marlene , Alejandro Morales Silvia Yolanda , Bastidas-Vaca Carlos , Jara-Castro María 
Published: June 2018

La presente investigación valoró el estado nutricional de 120 adolescentes de 14 a 18 años del Centro Educativo “Jerusalén” de la ciudad de Milagro, Ecuador, a través dela medición del perímetro abdominal, Índice de Masa Corporal (IMC) para la edad y una encuesta de frecuencia de consumo alimentario. Sus resultados indicaron que 72,5% de la muestra está normopeso, la relación IMC/obesidad abdominal reveló que 7,1% de las adolescentes con sobrepeso presentó obesidad abdominal y 64,3% riesgo de obesidad abdominal, para los varones obesos y con sobrepeso el riesgo de obesidad abdominal fue de 57,1% y 62,5% respectivamente; el 50% de los adolescentes con IMC normal presentó riesgo de obesidad abdominal y 4% obesidad abdominal, en las adolescentes fue de 48,9% y 2,2% respectivamente, 22% de las adolescentes manifestó sobrepeso y 14% de los varones tenían obesidad; en cuanto a hábitos alimentarios, 90% consume comida chatarra y snacks durante la colación. Estas cifras apuntan, al riesgo de manifestaciones tempranas de enfermedades metabólicas, de alto costo social y económico para la familia y el estado, lo que amerita la urgente implementación de políticas nutricionales que mejoren la calidad de vida de la población adolescente considerando su entorno integral. Abstract The present study evaluated the nutritional status of 120 adolescents aged 14 to 18 years of the "Jerusalem" Educational Center of the city of Milagro, Ecuador, through the measurement of the abdominal perimeter, Body Mass Index (BMI) for age and a survey of food consumption frequency. Their results show that 72.5% of the sample is normal weight, the ratio BMI/abdominal obesity revealed that 7.1% of overweight adolescents presented abdominal obesity and 64.3% risk of abdominal obesity, for obese and overweight males, the risk of abdominal obesity was 57.1% and 62.5% respectively; 50% of male adolescents with normal BMI had a risk of abdominal obesity and 4% of abdominal obesity, in female adolescents was 48.9% and 2.2% respectively; 22% of female adolescents were overweight and 14% of men had obesity; in terms of eating habits, 90% consumes junk food and snacks during collation. These date point to the risk of early manifestations of metabolic diseases, high social and economic cost to the family and the state, which deserves the urgent implementation of nutritional policies that improve the quality of life of the adolescent population considering its integral environment.
Nivel de corresponsabilidad de los beneficiarios del Bono de Desarrollo Humano del cantón El Triunfo / Level of co-responsibility of the beneficiaries of the Human Development Payment in the canton of El Triunfo
Authors: Romero Cerdán Leidi , Roldán Franco Lissette , Benitez Astudillo Javier 
Published: June 2018

El presente artículo es producto de la investigación realizada para determinar el nivel de corresponsabilidad de los beneficiaros del Bono de Desarrollo Humano, BDH, en el cantón El Triunfo, provincia del Guayas, ya que en economías como las de Ecuador el desarrollo de temas sociales es de relevancia, debido a que los niveles de pobreza son altos a pesar de los intentos del Estado por erradicarla. Los resultados obtenidos por medio de una investigación aplicada demostraron las causas de la falta de interés en la corresponsabilidad por parte de los beneficiarios. Los tipos de investigación que se utilizaron en este proyecto, además de la investigación aplicada, fueron bibliográfica y de campo, dentro de este proyecto se consideró relevante e importante para las madres de familia la idea de poder adquirir conocimientos y herramientas para administrar sus recursos y generar emprendimiento.Palabras Clave: Corresponsabilidad, Bono de desarrollo Humano, Economía. This article is the result of research conducted to determine the level of responsibility of the beneficiaries of the Bono de Desarrollo Humano, BDH, Canton El Triunfo, Guayas Province, since in economies such as Ecuador developing social issues is relevance, because poverty levels are high despite attempts by the state to eradicate . The results obtained through applied research demonstrated the causes of the lack of interest in stewardship by beneficiaries. The types of research that were used in this project as well as applied research, literature and field were within this project was considered relevant and important for mothers the idea of acquiring knowledge and tools to manage their resources and generating enterprise.
La normalización de la gestión editorial de la revista CIENCIA UNEMI (2008-2015) / Standardization of editorial work for the journal, CIENCIA UNEMI (2008-2015)
Authors: Chaparro Martinez Exio , D’Armas Haydelba , Cardenas Cobos Jessenia , Villavicencio Morales Karla , D’Armas Mayra 
Published: June 2018

Este es un artículo de investigación cuyo objetivo es evaluar el ajuste de la revista CIENCIA UNEMI a las normas internacionales de presentación de publicaciones periódicas y la evaluación de la calidad de su proceso editorial. La muestra estuvo representada por los números comprendidos desde el año 2008 hasta el 2015 de la revista. Para el desarrollo de la metodología se utilizó una adaptación del modelo de evaluación propuesta por Delgado Lopéz-Cozar et al. (2006) quienes toman en consideración las normas ISO 8, ISO 2015, CBE 1994, UKSG 1994, ANSI, ACS 1997, entre otras. Los resultados arrojaron una media general de normalización de 84%, la cual se obtuvo de aquellas secciones consideradas fundamentales en los mecanismos actuales de difusión científica. El análisis de la normalización y del proceso editorial indica un buen nivel, no obstante, se recomiendan mejoras. Abstract This is a research paper whose objective is to evaluate the adjustment of the journal CIENCIA UNEMI to international standards of presentation of regular publications and the evaluation of the quality of the editorial process in this journal. The sample was represented by the numbers ranging from 2008 to 2015 of the journal CIENCIA UNEMI. For the development of the methodology was used an adaptation of the evaluation model proposed by Delgado Lopéz-Cozar et al. (2006), who take into consideration the standards ISO 8, ISO 2015, CBE 1994, UKSG 1994, ANSI, ACS 1997, among others. The results showed an average of normalization of 84%, which was obtained from those sections considered fundamental in the current mechanisms of scientific dissemination. Analysis of standardization and the editorial process indicates a good level; however, improvements are recommended.
Exportación y productividad: evidencia a nivel de empresa del sector químico – farmacéutico / Export and productivity: evidence from chemical – pharmaceutical firms
Authors: Camino Mogro Segundo Marvin 
Published: June 2018

El presente trabajo analiza la producción del sector químico y productos farmacéuticos en España mediante la estimación de una función de producción. Se plantea un marco simple de estimación de funciones de producción utilizando los factores de producción tradicionales (capital, trabajo y materias primas). Los objetivos que se plantean en este estudio son dos. En primer lugar, la estimación de una función de producción para las empresas que forman este sector en España. En segundo lugar, el estudio de la productividad total de los factores (PTF) y en tercer lugar su relación con las exportaciones. Como principales conclusiones se pueden mencionar las siguientes: en primera instancia, el sector químico y productos farmacéuticos en España aporta al valor añadido bruto del total manufacturero español alrededor del 9%. Luego en la estimación de la función de producción se obtienen estimaciones plausibles de las elasticidades de la producción respecto de los diferentes factores de producción. Por último, la PTF presenta un patrón de crecimiento a lo largo del periodo analizado y se obtiene evidencia a favor de una relación positiva entre la PTF y la actividad exportadora. AbstractThis study analyzes the production of the chemical sector and pharmaceutical products in Spain by estimating a production function. It is posed a simple framework for estimating production functions by using the traditional production factors (capital, labor and raw materials). The objectives of this study are two. The first objective is to estimate a production function for the firms belonging to this sector in Spain. The second objective is to analyze the total factor productivity (TFP) and its relationship to exports. As main conclusions, it can be mentioned the following: First, the chemical and pharmaceutical products sector in Spain represents around 9% of gross added value of total manufacturing. Second, when estimating the production function, it is found plausible values for the estimated elasticity of traditional production. Finally, the TFP shows and increasing pattern over the analyzed period and it is found evidence in favor for a positive relationship between TFP and export activity.
Relación entre la diversificación de productos y la rentabilidad empresarial / Relationship between product diversification and corporate profitability
Authors: Puente Riofrio Mariana , Andrade Dominguez Francisco 
Published: June 2018

El objetivo del presente artículo es evidenciar avances investigativos respecto a propuestas teóricas, a partir de pruebas empíricas, sobre la relación de la diversificación de la cartera de productos en los resultados empresariales, subrayando en teorías de diversificación y rentabilidad; se busca analizar la dinámica de las empresas dentro de un proceso de transformación basada en alcanzar resultados rentables. Al momento de utilizar las proyecciones financieras en la investigación se determinó una relación entre el pasado y el futuro de la empresa, factor que permitió concluir que la rentabilidad empresarial es directamente proporcional a la diversificación de la cartera de productos de una empresa. AbstractThe aim of this paper is to show research progress about theoretical proposals from empirical evidence, on the relationship of diversifying products portfolio on business results, emphasizing diversification theories and profitability; it is sought to analyze the business dynamics within a transformation process based on achieving profitable results. At the time of using the financial projections in the research, a link between the past and the future of the company was determined; a factor which led us to conclude that corporate profitability is directly proportional to the portfolio diversification of goods in a company.