bluuebunny/crossref_metadata_2025_split huggingface dataset:
Similarity-based future common neighbors model for link prediction in complex networks
Authors: Li Shibao , Huang Junwei , Zhang Zhigang , Liu Jianhang , Huang Tingpei , Chen Haihua 
Published: November 2018

AbstractLink prediction aims to predict the existence of unknown links via the network information. However, most similarity-based algorithms only utilize the current common neighbor information and cannot get high enough prediction accuracy in evolving networks. So this paper firstly defines the future common neighbors that can turn into the common neighbors in the future. To analyse whether the future common neighbors contribute to the current link prediction, we propose the similarity-based future common neighbors (SFCN) model for link prediction, which accurately locate all the future common neighbors besides the current common neighbors in networks and effectively measure their contributions. We also design and observe three MATLAB simulation experiments. The first experiment, which adjusts two parameter weights in the SFCN model, reveals that the future common neighbors make more contributions than the current common neighbors in complex networks. And two more experiments, which compares the SFCN model with eight algorithms in five networks, demonstrate that the SFCN model has higher accuracy and better performance robustness.
Transcriptome profiling in the spathe of Anthurium andraeanum ‘Albama’ and its anthocyanin-loss mutant ‘Xueyu’
Authors: Li Zhiying , Wang Jiabin , Fu Yunliu , Gao Yu , Lu Hunzhen , Xu Li 
Published: November 2018

AbstractAnthurium andraeanum is a popular tropical ornamental plant. Its spathes are brilliantly coloured due to variable anthocyanin contents. To examine the mechanisms that control anthocyanin biosynthesis, we sequenced the spathe transcriptomes of ‘Albama’, a red-spathed cultivar of A. andraeanum, and ‘Xueyu’, its anthocyanin-loss mutant. Both long reads and short reads were sequenced. Long read sequencing produced 805,869 raw reads, resulting in 83,073 high-quality transcripts. Short read sequencing produced 347.79 M reads, and the subsequent assembly resulted in 111,674 unigenes. High-quality transcripts and unigenes were quantified using the short reads, and differential expression analysis was performed between ‘Albama’ and ‘Xueyu’. Obtaining high-quality, full-length transcripts enabled the detection of long transcript structures and transcript variants. These data provide a foundation to elucidate the mechanisms regulating the biosynthesis of anthocyanin in A. andraeanum.
High‐power‐density high‐efficiency LLC converter with an adjustable‐leakage‐inductance planar transformer for data centers
Authors: He Peiwen , Mallik Ayan , Cooke Gary , Khaligh Alireza 
Published: November 2018

LLC converters can achieve high efficiency, high‐ power density, wide gain range, and galvanic isolation. This study presents a high‐power‐density and high‐efficiency LLC converter with an adjustable‐leakage‐inductance planar transformer for the DC–DC conversion in data center power supplies. A planar transformer with adjustable leakage inductance is modelled and developed to provide an accurate design for resonant frequency and voltage gain. A detailed power loss analysis is performed. Furthermore, a thermal model is provided to aid in heat sink design. GaN devices are used in the converter to achieve high‐switching frequency and low‐switching loss. A 450 kHz, 360–400 VDC input, 12 VDC output, 750 W LLC converter prototype with an adjustable‐leakage‐inductance planar transformer is built and tested. The power density of the system is 15.4 W/cm3 including an auxiliary power supply. The peak efficiency of the overall system is over 95%.
Rheumatische Fehlstellungen an der HWS unter besonderer Berücksichtigung der C1/C2-Stabilität – Aktuelle Diagnostik und Therapiestrategien
Authors: Kothe Ralph 
Published: November 2018

ZusammenfassungDurch den zunehmenden Einsatz von Biologika hat sich das klinische Erscheinungsbild der rheumatoiden Arthritis (RA) in der täglichen Praxis verändert. Patienten mit einer isolierten atlanto-axialen Instabilität sind seltener geworden. Dafür rücken Patienten mit therapierefraktären Schmerzsyndromen der oberen Halswirbelsäule (HWS) und komplexen rheumatischen Deformitäten mit neurologischen Problemen vermehrt in den klinischen Fokus. Biologika können die Manifestation einer rheumatischen Instabilität an der HWS bei vielen Patienten verhindern, haben aber keinen Einfluss auf den klinischen Verlauf bei bereits bestehender biomechanischer Instabilität oder hartnäckigen Schmerzsyndromen aufgrund von knöchernen Destruktionen. Hier ist die operative Therapie für die meisten Patienten die einzig sinnvolle Behandlungsoption. Für die Fusion des atlanto-axialen Gelenkes stehen verschiedene Techniken mit hoher Fusionsrate und geringer eingriffsbedingter Morbidität zur Verfügung. Dabei sind die Besonderheiten der RA zu berücksichtigen (Knochendestruktion, Erweiterung der Vertebralisfurche, Biologikatherapie). Bei komplexen zervikalen Instabilitäten sind langstreckige Fusionen vom Okziput bis in die obere BWS notwendig. Die verbesserten operativen Techniken ermöglichen auch bei dieser schwierigen Patientengruppe eine sichere und komplikationsarme operative Versorgung.
The Use of Platelet-Rich Plasma in Symptomatic Knee Osteoarthritis
Authors: Southworth Taylor , Naveen Neal , Tauro Tracy , Leong Natalie , Cole Brian 
Published: November 2018

AbstractWith average life expectancy and the rising prevalence of obesity, osteoarthritis (OA) is creating an increasingly large financial and physical burden on the U.S. population today. As the body ages and experiences trauma, articular cartilage surfaces in joints are gradually worn away, leading to OA. Traditionally, treatment options have included lifestyle modifications, pain management, and corticosteroid injections, with joint replacement reserved for those who have exhausted nonsurgical measures. More recently, hyaluronic acid, micronized dehydrated human amniotic/chorionic membrane tissue, and platelet-rich plasma (PRP) injections have started to gain traction. PRP has been shown to have both anti-inflammatory effects through growth factors such as transforming growth factor-β and insulin-like growth factor 1, and stimulatory effects on mesenchymal stem cells and fibroblasts. Multiple studies have indicated that PRP is superior to hyaluronic acid and corticosteroids in terms of improving patient-reported pain and functionality scores. Unfortunately, there are many variations in PRP preparation, and lack of standardization in factors, such as speed and duration of centrifugation, leads to wide ranges of platelet and leukocyte concentrations. This review examines the current literature addressing the use of PRP in symptomatic knee OA and addresses suggestions for future studies in this area.
Neurointensivmedizin: aneurysmatische Subarachnoidalblutung – State of the Art
Authors: Müller Daniela , Müller Oliver 
Published: November 2018

ZusammenfassungDie spontane, nicht traumatische Subarachnoidalblutung ist eine lebensbedrohliche Erkrankung, die mit vielfältigen Komplikationen und einer hohen Morbidität und Mortalität vergesellschaftet ist. In den ersten 24 Stunden hat die Ausschaltung der Blutungsursache Vorrang. Die Patienten sollen intensivmedizinisch überwacht und behandelt werden. Stringente Diagnostik und konsequente Behandlung verbessern das Outcome der Patienten nachweislich.
Traumatische Verletzungen des zentralen Nervensystems
Authors: Walter Johannes , Zweckberger Klaus 
Published: November 2018

ZusammenfassungTraumatische Verletzungen des zentralen Nervensystems stellen die Folge einer äußeren Gewalteinwirkung auf Gehirn oder Rückenmark dar. Sowohl das Schädel-Hirn-Trauma als auch das spinale Trauma sind dynamische Krankheitsbilder, die besondere Anforderungen an Diagnostik und Therapie stellen und somit in spezialisierten Zentren versorgt werden sollten.
Acceleration and delay in bilingual, trilingual and multilingual German-Romance children
Authors: Arnaus Gil Laia , Müller Natascha 
Published: November 2018

AbstractA production test with 91 bilingual, trilingual and multilingual children (who acquire more than three languages) elicited finite verbs in German. In comparison with monolinguals, the children were accelerated with respect to finite verb placement in main clauses. FollowingBiberauer & Richards (2006), the EPP feature of T can be satisfied in different ways across languages: If a DP is necessary, which is the case for adult German, it can either be raised from Spec,vP to Spec,TP (in which case the finite verb surfaces in non-clause-final position) or it is pied-piped to Spec,TP. In the latter case, the whole vP is placed in the specifier of TP, giving rise to V-final patterns. The bilingual, trilingual and multilingual children prefer Spec-raising to Spec-pied-piping. We argue that the choice of the means for EPP satisfaction in the German of the multilingual children is influenced by the respective Romance language (French/Spanish).
Translanguaging revisited
Authors: Rosiers Kirsten 
Published: November 2018

AbstractThis article takes a translanguaging perspective and is based on linguistic-ethnographic research. It investigates the participants’ interactional engagement with their linguistic repertoire in two multilingual Belgian primary classrooms and the pedagogical potential of these practices. Analyses demonstrate that teachers can transform translanguaging as a pedagogy into practice by permitting pupils to interact, thereby co-constructing knowledge and valorizing their own and others’ translanguaging. The article also shows how translanguaging practices are influenced by changes in evolving constellations and dynamics of a group, by content, and by socio-situational, cognitive and linguistic factors. At the same time, the article highlights challenges for translanguaging research, policy and pedagogy. With respect to further studies in this area, reflection is recommended on the definition of translanguaging and the integration of speakers’ attitudes in research. In terms of policy, the article considers as to how best to reconcile a multilingual reality with a monolingual educational ideology and reflects on the relationship between macro level interventions and micro-interactional practices. For pedagogy, four challenges are highlighted: the degree of acceptance of translanguaging practices in schools, the commitment to developing the school language for academic tasks, the need to pay attention to the unequal treatment of languages, and the implementation of an innovative approach with a focus on teachers and the creation of a powerful learning environment.
Calibration of Thermocouple by Comparison against Standard Radiation Thermometer in a Blackbody Comparator
Authors: Trisna Beni Adi , Suherlan  , Hapiddin Asep , Zaini Helmi , Wiriadinata Hidayat , Zaid Ghufron 
Published: November 2018

Abstract
A set-up to calibrate thermocouple up to 1500 °C by comparison against radiation thermometer is recently established in Research Center for Metrology – LIPI (RCM – LIPI). A blackbody cavity, made of silicon carbide, is put in a single-zone-controller furnace as a comparator block. A radiation thermometer standard (worked at λ = 650 nm) is employed to determine the reference temperature of the calibration. In this work, a type B thermocouple is calibrated in the range of 1000 – 1500 °C. The expanded uncertainty (k = 2) is evaluated to be 2.4 °C at 1500 °C. The uncertainty due to inhomogeneity of the thermocouple contributes more than 50% (1.4 °C) of the total uncertainty.
Systolic Blood Pressure Trajectories in the Acute Phase and Clinical Outcomes in 2-Year Follow-up Among Patients With Ischemic Stroke
Authors: Li Changwei , Zhang Yonghong , Xu Tan , Peng Hao , Wang Dali , Xu Tian , Sun Yingxian , Bu Xiaoqing , Chen Chung-Shiuan , Wang Aili , Wang Jinchao , Li Qunwei , Ju Zhong , Geng Deqin , Zhang Jintao , Chen Jing , He Jiang ,   CATIS investigators
Published: November 2018

Abstract

BACKGROUND
Optimal blood pressure (BP) levels during acute ischemic stroke have not been established. We studied associations between systolic BP trajectories during acute phase and subsequent clinical outcomes among patients with ischemic stroke.

METHODS
A total of 4,036 patients with acute ischemic stroke and elevated BP from the China Antihypertensive Trial in Acute Ischemic Stroke trial were included in this analysis. Three BPs were measured every 2 hours in day 1, every 4 hours during days 2 and 3, and every 8 hours thereafter until hospital discharge or death. Clinical outcomes were assessed at 3, 12, and 24 months. Latent variable mixture modeling was used to identify subgroups that share a similar underlying trajectory of systolic BP during the first 7 days after stroke onset. Logistic regression and Cox proportional hazards models were used to examine the associations between systolic BP trajectories and clinical outcomes during follow-up.

RESULTS
We identified 5 systolic BP trajectories of high, high-to-moderate-low, moderate-high, moderate-low, and low. Compared to participants in high trajectory, multiple-adjusted odds ratios (95% confidence interval) of all-cause mortality at 3 months for individuals in high-to-moderate-low, moderate-high, moderate-low, and low were 0.34 (0.15–0.77), 0.58 (0.32–1.04), 0.29 (0.15–0.56), and 0.56 (0.26–1.19), respectively. Likewise, the corresponding hazard ratios for all-cause mortality in 24 months were 0.66 (0.44–1.00), 0.74 (0.53–1.05), 0.45 (0.32–0.66), and 0.61 (0.40–0.93), respectively. Similar associations were observed for recurrent stroke and cardiovascular disease, and in both the intervention and control groups.

CONCLUSIONS
Patients with moderate-low systolic BP during acute ischemic stroke had a lower risk of adverse clinical outcomes.
APOE-ε4 Genotype is Associated with Elevated Post-Concussion Symptoms in Military Veterans with a Remote History of Mild Traumatic Brain Injury
Authors: Merritt Victoria C , Lapira Kristina M , Clark Alexandra L , Sorg Scott F , Werhane Madeleine L , Jak Amy J , Bondi Mark W , Schiehser Dawn M , Delano-Wood Lisa 
Published: November 2018

Abstract

Objective
We evaluated the influence of the APOE-ε4 allele on post-concussive symptoms in military Veterans with a remote history of mild traumatic brain injury (mTBI).

Method
Participants (N = 77) were administered neuropsychiatric measures, on average, approximately 5 years following their most recent mTBI and provided a DNA sample for APOE genotyping. Veterans were divided into two groups based on their ε4 status (n = 14 ε4+, n = 63 ε4–). The Neurobehavioral Symptom Inventory (NSI) was the primary outcome measure, from which a total score was derived, as well as three symptom clusters (somatic, cognitive, and affective).

Results
ANCOVAs showed a significant main effect of ε4 genotype on the NSI total score and somatic symptom cluster after adjusting for posttraumatic stress symptoms and mTBI history (p = .019–.028, ηp2 = .064–.073), such that ε4+ Veterans endorsed significantly greater symptoms than ε4– Veterans.

Conclusions
Our findings suggest that genetic risk may help to explain the poorer long-term outcomes often observed in this population.
Bayesian inference of networks across multiple sample groups and data types
Authors: Shaddox Elin , Peterson Christine B , Stingo Francesco C , Hanania Nicola A , Cruickshank-Quinn Charmion , Kechris Katerina , Bowler Russell , Vannucci Marina 
Published: November 2018

SummaryIn this article, we develop a graphical modeling framework for the inference of networks across multiple sample groups and data types. In medical studies, this setting arises whenever a set of subjects, which may be heterogeneous due to differing disease stage or subtype, is profiled across multiple platforms, such as metabolomics, proteomics, or transcriptomics data. Our proposed Bayesian hierarchical model first links the network structures within each platform using a Markov random field prior to relate edge selection across sample groups, and then links the network similarity parameters across platforms. This enables joint estimation in a flexible manner, as we make no assumptions on the directionality of influence across the data types or the extent of network similarity across the sample groups and platforms. In addition, our model formulation allows the number of variables and number of subjects to differ across the data types, and only requires that we have data for the same set of groups. We illustrate the proposed approach through both simulation studies and an application to gene expression levels and metabolite abundances on subjects with varying severity levels of chronic obstructive pulmonary disease. Bayesian inference; Chronic obstructive pulmonary disease (COPD); Data integration; Gaussian graphical model; Markov random field prior; Spike and slab prior.
Outbreak of Tattoo-associated Nontuberculous Mycobacterial Skin Infections
Authors: Griffin Isabel , Schmitz Ann , Oliver Christine , Pritchard Scott , Zhang Guoyan , Rico Edhelene , Davenport Emily , Llau Anthoni , Moore Emily , Fernandez Danielle , Mejia-Echeverry Alvaro , Suarez Juan , Noya-Chaveco Pedro , Elmir Samir , Jean Reynald , Pettengill James B , Hollinger Katherine A , Chou Kyson , Williams-Hill Donna , Zaki Sherif , Muehlenbachs Atis , Keating M Kelly , Bhatnagar Julu , Rowlinson Marie-Claire , Chiribau Calin , Rivera Lillian 
Published: November 2018

AbstractBackgroundOn 29 April 2015, the Florida Department of Health in Miami-Dade County (DOH Miami-Dade) was notified by a local dermatologist of 3 patients with suspected nontuberculous mycobacterial (NTM) infection after receiving tattoos at a local tattoo studio.MethodsDOH Miami-Dade conducted interviews and offered testing, described below, to tattoo studio clients reporting rashes. Culture of clinical isolates and identification were performed at the Florida Bureau of Public Health Laboratories. Characterization of NTM was performed by the Centers for Disease Control and Prevention and the US Food and Drug Administration (FDA), respectively. Whole-genome sequencing (WGS) and single-nucleotide polymorphism (SNP) analyses were used to construct a phylogeny among 21 Mycobacterium isolates at the FDA.ResultsThirty-eight of 226 interviewed clients were identified as outbreak-associated cases. Multivariate logistic regression revealed that individuals who reported gray tattoo ink in their tattoos were 8.2 times as likely to report a rash (95% confidence interval, 3.1–22.1). Multiple NTM species were identified in clinical and environmental specimens. Phylogenetic results from environmental samples and skin biopsies indicated that 2 Mycobacterium fortuitum isolates (graywash ink and a skin biopsy) and 11 Mycobacterium abscessus isolates (5 from the implicated bottle of graywash tattoo ink, 2 from tap water, and 4 from skin biopsies) were indistinguishable. In addition, Mycobacterium chelonae was isolated from 5 unopened bottles of graywash ink provided by 2 other tattoo studios in Miami-Dade County.ConclusionsWGS and SNP analyses identified the tap water and the bottle of graywash tattoo ink as the sources of the NTM infections.
Measles Seroprevalence and Vaccine Responses in Human Immunodeficiency Virus–infected Adolescents and Adults: A Systematic Review
Authors: Loevinsohn Gideon , Rosman Lori , Moss William J 
Published: November 2018

AbstractBackgroundThe World Health Organization (WHO) recommends an additional dose of measles-containing vaccine (MCV) for human immunodeficiency virus (HIV)–infected children receiving highly active antiretroviral therapy following immune reconstitution. We conducted a systematic review to synthesize available evidence regarding measles seroprevalence and measles vaccine immunogenicity, efficacy, and safety in HIV-infected adolescents and adults to provide the evidence base for recommendations on the need for measles vaccination.MethodsWe conducted searches of 8 databases through 26 September 2017. Identified studies were screened independently by 2 reviewers.ResultsThe search identified 30 studies meeting inclusion criteria. Across studies, measles seroprevalence among HIV-infected adolescents and adults was high (median, 92%; 27 studies), with no significant difference compared to HIV-uninfected participants (10 studies). In 6 studies that evaluated the immunogenicity of MCVs among seronegative HIV-infected adults, measles seropositivity at end of follow-up ranged from 0% to 56% (median, 39%). No severe adverse events were reported following measles vaccination in HIV-infected patients.ConclusionsBased on similar measles seroprevalence between HIV-infected and HIV-uninfected adolescents and adults, and the low response to vaccination, these studies do not support the need for an additional dose of MCV in HIV-infected adolescents and adults. These findings support WHO guidelines that measles vaccine be administered to potentially susceptible, asymptomatic HIV-infected adults, and may be considered for those with symptomatic HIV infection if not severely immunosuppressed. Measles-susceptible adolescents and adults, regardless of HIV status, may require targeted vaccination efforts to reach critical vaccination thresholds and achieve regional elimination goals.
Prevalence and risk factors of root resorption of adjacent teeth in maxillary canine impaction, among untreated children and adolescents
Authors: Rafflenbeul Frédéric , Gros Catherine-Isabelle , Lefebvre François , Bahi-Gross Sophie , Maizeray Raphaëlle , Bolender Yves 
Published: November 2018

SummaryObjectivesThe aim of this retrospective study was to assess in maxillary canine impaction cases both the prevalence of root resorption of adjacent teeth among untreated children and adolescents, and its associated risk factors.Subjects and methodsSixty subjects (mean age 12.2 years; SD 1.9; range 8–17 years) with 83 displaced maxillary canines and without any past or ongoing orthodontic treatment were included in this study. The presence of root resorption was evaluated on images from a single cone beam computed tomography (CBCT) unit. Potential risk factors were measured on the CBCT images and on panoramic reconstructions of the 3D data sets. The sample was characterized by descriptive statistics and multiple logistic regressions were performed to predict root resorption.ResultsRoot resorption of at least one adjacent tooth was detected in 67.5 per cent of the affected quadrants. It was found that 55.7 per cent of the lateral incisors, 8.4 per cent of the central incisors, and 19.5 per cent of first premolars were resorbed. Of the detected resorptions, 71.7 per cent were considered slight, 14.9 per cent moderate, and 13.4 per cent severe. Contact between the displaced canine(s) and the adjacent teeth roots was the only identified statistically significant risk factor, all teeth being considered (odds ratio [OR] = 18.7, 95% confidence interval: 2.26–756, P < 0.01). An enlarged canine dental follicle, a peg upper lateral, or an upper lateral agenesis were not significantly associated with root resorption of adjacent teeth, nor were age nor gender.ConclusionsRoot resorption of adjacent teeth was detected in more than two-thirds of a sample of sixty untreated children and adolescents.
Exponential Concentration for Zeroes of Stationary Gaussian Processes
Authors: Basu Riddhipratim , Dembo Amir , Feldheim Naomi , Zeitouni Ofer 
Published: November 2018

Abstract
We show that for any centered stationary Gaussian process of absolutely integrable covariance, whose spectral measure has compact support, or finite exponential moments (and some additional regularity), the number of zeroes of the process in $[0,T]$ is within $\eta T$ of its mean value, up to an exponentially small in $T$ probability.