bluuebunny/crossref_metadata_2025_split huggingface dataset:
FACTORS IMPACT ON THE SATISFACTION OF PART-TIME STUDENTS ON THE QUALITY OF EDUCATIONAL SUPPORT SERVICES IN TRA VINH UNIVERSITY
Authors: Nguyen Nguyen Van , Nguyen Thoai Thanh , Lam Dien Son 
Published: June 2019

In the market economy, academic activities have long been considered as “a kind of service” with increasingly high competition. In order to increase competitiveness of Tra Vinh University (TVU) by improving support services for part-time students, this research has been implemented to identify factors that affect to part-time students’ satisfaction related to quality of academic support services at TVU. The research was conducted by interviewing experts and analyzing questionnaire-based primary data with sample size n = 598 and statistical error 1 =5%. The results indicated 6 factors affecting the satisfaction of part-time students with regard to the quality of the support services at TVU including: (1) Facilities (2) Assurance, (3) Reliability, (4) Responsiveness, (5) care and (6) other Support Services. Therefore, the improvement in these factors will make students be more satisfied as well as increase competitiveness of TVU
SOUTHERN CAI LUONG: CURRENT SITUATION AND ORIENTATION TO PROMOTION OF ITS VALUES OF CULTURAL HERITAGE
Authors: Nguyen Bach Thi Truc 
Published: June 2019

Cai Luong is a unique stage art of Southern Vietnam and original cultural and artistic product of the nation. Over 100 years of existence and development, today’s Cai Luong is a new trend in the era of international integration. Within the scope of this paper, the writer analyses and evaluates this type of art based on data collected and recorded during the field trips in the Southern Vietnam region (since 2014 up to present). This research finding reflects the real life of Cai Luong in the South and proposes the solutions. Specifically, from difficulties and challenges identified by the authors, directors, audiences of Cai Luong, this paper proposes the practical solutions in two aspects: cultural and artistic management and application of interdisciplinary studies into subjects such as Literature, Cultural studies and Arts studies toward preserving and developing the values of cultural heritage of the Cai Luong stage in the contemporary context.
The Case of H2C3O Isomers, Revisited: Solving the Mystery of the Missing Propadienone
Authors: Shingledecker Christopher N. , Álvarez-Barcia Sonia , Korn Viktoria H. , Kästner Johannes 
Published: June 2019

Abstract
To date, two isomers of H2C3O have been detected, namely, propynal (HCCCHO) and cylclopropenone (c-H2C3O). A third, propadienone (CH2CCO), has thus far eluded observers despite the fact that it is the lowest in energy of the three. This previously noted result is in contradiction to the minimum energy principle, which posits that the abundances of isomers in interstellar environments can be predicted based on their relative stabilities and suggests, rather, the importance of kinetic over thermodynamic effects in explaining the role of such species. Here, we report results of ab initio quantum chemical calculations of the reaction between H and (a) HC3O, (b) H2C3O (both propynal and propadienone), and (c) CH2CHCO. We have found that, among all possible reactions between atomic hydrogen and either propadienone or propynal, only the destruction of propadienone is barrierless and exothermic. That this destruction pathway is indeed behind the nondetection of CH2CCO is further suggested by our finding that the product of this process, the radical CH2CHCO, can subsequently react barrierlessly with H to form propenal (CH2CHCHO) which has, in fact, been detected in regions where the other two H2C3O isomers are observed. Thus, these results not only shed light on a previously unresolved astrochemical mystery, but also further highlight the importance of kinetics in understanding the abundances of interstellar molecules.
Revisiting the Temperature of the Diffuse ISM with CHESS Sounding Rocket Observations
Authors: Kruczek Nicholas , France Kevin , Hoadley Keri , Fleming Brian , Nell Nicholas 
Published: June 2019

Abstract
Measuring the temperature and abundance patterns of clouds in the interstellar medium (ISM) provides an observational basis for models of the physical conditions within the clouds, which play an important role in studies of star and planet formation. The Colorado High-resolution Echelle Stellar Spectrograph is a far-ultraviolet rocket-borne instrument designed to study the atomic-to-molecular transitions within diffuse molecular and translucent cloud regions. The final two flights of the instrument observed

Scorpii (β Sco) and γ Arae. We present flight results of interstellar molecular hydrogen excitation on the sightlines, including measurements of the column densities and temperatures. These results are compared to previous values that were measured using the damping wings of low J″ H

absorption features. For β Sco, we find that the derived column density of the J″ = 1 rotational level differs by a factor of 2–3 when compared to the previous observations. We discuss the discrepancies between the two measurements and show that the source of the difference is due to the opacity of higher rotational levels contributing to the J″ = 1 absorption wing, increasing the inferred column density in the previous work. We extend this analysis to 9 Copernicus and 13 Far-Ultraviolet Spectroscopic Explorer spectra to explore the interdependence of the column densities of different rotational levels and how the H

kinetic temperature is influenced by these relationships. We find a revised average gas kinetic temperature of the diffuse molecular ISM of T
01 = 68 ± 13 K, 12% lower than the value found previously.
Variability of Low-ionization Broad Absorption-line Quasars Based on Multi-epoch Spectra from the Sloan Digital Sky Survey
Authors: Yi W. , Brandt W. N. , Hall P. B. , Vivek M. , Grier C. J. , Ak N. Filiz , Schneider D. P. , McGraw S. M. 
Published: June 2019

Abstract
We present absorption variability results for 134 bona fide Mg ii broad absorption-line (BAL) quasars at 0.46 ≲ z ≲ 2.3 covering days to ∼10 yr in the rest frame. We use multiple-epoch spectra from the Sloan Digital Sky Survey, which has delivered the largest such BAL variability sample ever studied. Mg ii-BAL identifications and related measurements are compiled and presented in a catalog. We find a remarkable time-dependent asymmetry in the equivalent width (EW) variation from the sample, such that weakening troughs outnumber strengthening troughs, the first report of such a phenomenon in BAL variability. Our investigations of the sample further reveal that (i) the frequency of BAL variability is significantly lower (typically by a factor of 2) than that in high-ionization BALQSO samples, (ii) Mg ii-BAL absorbers tend to have relatively high optical depths and small covering factors along our line of sight, (iii) there is no significant EW-variability correlation between Mg ii troughs at different velocities in the same quasar, and (iv) the EW-variability correlation between Mg ii and Al iii BALs is significantly stronger than that between Mg ii and C iv BALs at the same velocities. These observational results can be explained by a combined transverse-motion/ionization-change scenario, where transverse motions likely dominate the strengthening BALs while ionization changes and/or other mechanisms dominate the weakening BALs.
Constraints on Dark Matter Microphysics from the Milky Way Satellite Population
Authors: Nadler Ethan O. , Gluscevic Vera , Boddy Kimberly K. , Wechsler Risa H. 
Published: June 2019

Abstract
Alternatives to the cold, collisionless dark matter (DM) paradigm in which DM behaves as a collisional fluid generically suppress small-scale structure. Herein we use the observed population of Milky Way (MW) satellite galaxies to constrain the collisional nature of DM, focusing on DM–baryon scattering. We first derive conservative analytic upper limits on the velocity-independent DM–baryon scattering cross section by translating the upper bound on the lowest mass of halos inferred to host satellites into a characteristic cutoff scale in the linear matter power spectrum. We then confirm and improve these results through a detailed probabilistic inference of the MW satellite population that marginalizes over relevant astrophysical uncertainties. This yields 95% confidence upper limits on the DM–baryon scattering cross section of 6 × 10−30 cm2 (10−27 cm2) for DM particle masses m

χ
of 10 keV (10 GeV); these limits scale as m

χ

1/4 for m

χ
≪ 1 GeV and m

χ
for m

χ
≫ 1 GeV. This analysis improves upon cosmological bounds derived from cosmic-microwave-background anisotropy measurements by more than three orders of magnitude over a wide range of DM masses, excluding regions of parameter space previously unexplored by other methods, including direct-detection experiments. Our work reveals a mapping between DM–baryon scattering and other alternative DM models, and we discuss the implications of our results for warm and fuzzy DM scenarios.
A Giant Intragroup Nebula Hosting a Damped
Absorber at z = 0.313
Authors: Chen Hsiao-Wen , Boettcher Erin , Johnson Sean D. , Zahedy Fakhri S. , Rudie Gwen C. , Cooksey Kathy L. , Rauch Michael , Mulchaey John S. 
Published: June 2019

Abstract
This Letter reports the discovery of spatially extended line-emitting nebula, reaching to ≈100 physical kpc (pkpc) from a damped

absorber (DLA) at z
DLA = 0.313 along the sightline toward quasi-stellar object (QSO) PKS 1127−145 (z
QSO = 1.188). This DLA was known to be associated with a galaxy group of dynamical mass M
group ∼ 3 × 1012
M
⊙, but its physical origin remained ambiguous. New wide-field integral field observations revealed a giant nebula detected in [O ii], Hβ, [O iii], Hα, and [N ii] emission, with the line-emitting gas following closely the motions of group galaxies. One of the denser streams passes directly in front of the QSO with kinematics that are consistent with the absorption profiles recorded in the QSO echelle spectra. The emission morphology, kinematics, and line ratios of the nebula suggest that shocks and turbulent mixing layers, produced as a result of stripped gaseous streams moving at supersonic speed across the ambient hot medium, contribute significantly to the ionization of the gas. While the DLA may not be associated with any specific detected member of the group, both the kinematic and dust properties are consistent with the DLA originating in streams of gas stripped from sub-L
* group members at ≲25 pkpc from the QSO sightline. This study demonstrates that gas stripping in low-mass galaxy groups is effective in releasing metal-enriched gas from star-forming regions, producing absorption systems in QSO spectra, and that combining absorption and emission-line observations provides an exciting new opportunity for studying gas and galaxy co-evolution.
Rising from Ashes or Dying Flash? The Mega Outburst of Small Comet 289P/Blanpain in 2013∗
Authors: Ye 叶 Quanzhi 泉志 , Clark David L. 
Published: June 2019

Abstract
Jupiter-family comet 289P/Blanpain was first discovered in 1819 and was then lost for ∼200 years, only to be rediscovered in 2003 as a small, weakly active comet. The comet is associated with the Phoenicids, an otherwise minor meteor shower that produced significant outbursts in 1956 and 2014. The shower points to the existence of significant mass-loss events of P/Blanpain in recent history. P/Blanpain was recovered during an apparent large outburst in 2013 July at an appreciable heliocentric distance of 3.9 au, with brightness increase of 9 mag, making it one of the largest comet outbursts ever observed. Here we present an analysis of archival data taken by several telescopes. We find that the 2013 outburst has produced ∼108 kg of dust, which accounts for a modest fraction (∼1%) of the mass of P/Blanpain’s nucleus as measured in 2004. Based on analysis of long-term light curve and modeling of coma morphology, we conclude that the 2013 outburst was most likely driven by the crystallization of amorphous water ice triggered by a spin-up disruption of the nucleus. A dust dynamical model shows that a small fraction of the dust ejecta will reach the Earth in 2036 and 2041, but are only expected to produce minor enhancements to the Phoenicid meteor shower. The 2013 outburst of P/Blanpain, though remarkable for a comet of small size, does not necessary imply a catastrophic disruption of the nucleus. The upcoming close encounter of P/Blanpain in 2020 January will provide an opportunity to examine the current state of the comet.
Genome-Wide Transcriptional Analysis Reveals Novel AhR Targets That Regulate Dendritic Cell Function during Influenza A Virus Infection
Authors: Franchini Anthony M , Myers Jason R , Jin Guang-Bi , Shepherd David M , Lawrence B Paige 
Published: June 2019

Abstract
Activation of the ligand inducible aryl hydrocarbon receptor (AhR) during primary influenza A virus infection diminishes host responses by negatively regulating the ability of dendritic cells (DC) to prime naive CD8+ T cells, which reduces the generation of CTL. However, AhR-regulated genes and signaling pathways in DCs are not fully known. In this study, we used unbiased gene expression profiling to identify differentially expressed genes and signaling pathways in DCs that are modulated by AhR activation in vivo. Using the prototype AhR agonist TCDD, we identified the lectin receptor Cd209a (DC-SIGN) and chemokine Ccl17 as novel AhR target genes. We further show the percentage of DCs expressing CD209a on their surface was significantly decreased by AhR activation during infection. Whereas influenza A virus infection increased CCL17 protein levels in the lung and lung-draining lymph nodes, this was significantly reduced following AhR activation. Targeted excision of AhR in the hematopoietic compartment confirmed AhR is required for downregulation of CCL17 and CD209a. Loss of AhR’s functional DNA-binding domain demonstrates that AhR activation alone is necessary but not sufficient to drive downregulation. AhR activation induced similar changes in gene expression in human monocyte-derived DCs. Analysis of the murine and human upstream regulatory regions of Cd209a and Ccl17 revealed a suite of potential transcription factor partners for AhR, which may coregulate these genes in vivo. This study highlights the breadth of AhR-regulated pathways within DCs, and that AhR likely interacts with other transcription factors to modulate DC functions during infection.
CD27 Promotes CD4+ Effector T Cell Survival in Response to Tissue Self-Antigen
Authors: Remedios Kelly A. , Meyer Lauren , Zirak Bahar , Pauli Mariela L. , Truong Hong-An , Boda Devi , Rosenblum Michael D. 
Published: June 2019

Abstract
Signaling through CD27 plays a role in T cell activation and memory. However, it is currently unknown how this costimulatory receptor influences CD4+ effector T (Teff) cells in inflamed tissues. In the current study, we used a murine model of inducible self-antigen expression in the epidermis to elucidate the functional role of CD27 on autoreactive Teff cells. Expression of CD27 on Ag-specific Teff cells resulted in enhanced skin inflammation when compared with CD27-deficient Teff cells. CD27 signaling promoted the accumulation of IFN-γ and IL-2–producing T cells in skin draining lymph nodes in a cell-intrinsic fashion. Surprisingly, this costimulatory pathway had minimal effect on early T cell activation and proliferation. Instead, signaling through CD27 resulted in the progressive survival of Teff cells during the autoimmune response. Using BH3 profiling to assess mitochondrial cell priming, we found that CD27-deficient cells were equally as sensitive as CD27-sufficient cells to mitochondrial outer membrane polarization upon exposure to either BH3 activator or sensitizer peptides. In contrast, CD27-deficient Teff cells expressed higher levels of active caspase 8. Taken together, these results suggest that CD27 does not promote Teff cell survival by increasing expression of antiapoptotic BCL2 family members but instead acts by preferentially suppressing the cell-extrinsic apoptosis pathway, highlighting a previously unidentified role for CD27 in augmenting autoreactive Teff cell responses.
Repeatedly adopting power postures does not affect hormonal correlates of dominance and affiliative behavior
Authors: Metzler Hannah , Grèzes Julie 
Published: June 2019

Background
Adopting expansive vs. constrictive postures related to high vs. low levels of social power has been suggested to induce changes in testosterone and cortisol levels, and thereby to mimic hormonal correlates of dominance behavior. However, these findings have been challenged by several non-replications recently. Despite this growing body of evidence that does not support posture effects on hormone levels, the question remains as to whether repeatedly holding postures over time and/or assessing hormonal responses at different time points would yield different outcomes. The current study assesses these methodological characteristics as possible reasons for previous null-findings. Additionally, it investigates for the first time whether expansive and constrictive postures impact progesterone levels, a suggested correlate of affiliative motives and behavior. By testing the effects of repeated but short posture manipulations in between the blocks of a social task while using a cover story, it further fulfills the conditions previously raised as potentially necessary for the effects to occur.

Methods
A total of 82 male participants repeatedly adopted an expansive or constrictive posture for 2 min in between blocks of a task that consisted in categorizing faces based on first impressions. Saliva samples were taken at two different time points in a time window in which hormonal responses to stress, competition and other manipulations are known to be strongest.

Results
Neither testosterone and cortisol levels linked to dominance behaviors, nor progesterone levels related to affiliative tendencies, responded differently to adopting expansive as opposed to constrictive postures. The present results suggest that even repeated power posing in a context where social stimuli are task-relevant does not elicit changes in hormone levels.
Mir-421 in plasma as a potential diagnostic biomarker for precancerous gastric lesions and early gastric cancer
Authors: Chen Jianlin , Wu Lihua , Sun Yifan , Yin Qi , Chen Xianhua , Liang Siqun , Meng Qingyan , Long Haihua , Li Fangying , Luo Changjun , Xiao Xiaorong 
Published: June 2019

Objective
MicroRNA (miR)-421 plays a key role in cancer progression. It has been reported that circulating miR-421may be a potential tumor marker for the diagnosis of several cancers. However, the role of miR-421 in plasma as a potential biomarker in the diagnosis of precancerous gastric lesions (Pre) and early-stage gastric cancer (GC) remains poorly understood. In this study, we investigated miR-421 in plasma as a novel potential biomarker for the detection of precancerous gastric lesions and early-stage (GC).

Materials & Methods
The miRNA content was determined by quantitative real-time polymerase chain reaction (qRT-PCR). MiR-421 content in all subjects was normalized by endogenous miRNA (miR-16). The diagnostic value of miR-421 for Pre and GC was assessed by comparing receiver operating characteristic (ROC) analysis with traditional tumor markers, including CEA, CA125, CA153, CA211 and CA50. The correlation between the expression of miR-421 and the pathological characteristics of Pre and GC was analyzed.

Results
Elevated expression of miR-421 in plasma can robustly distinguish the normal population from Pre and GC cases, especially in the early stages of gastric cancer cases (all p < 0.05). The ROC analyses showed that the area under the ROC curve (AUC), sensitivity, accuracy and Youden index of miR-421 were superior to traditional tumor markers (CEA, CA125, CA153, CA211, and CA50) in GC diagnosis, while its specificity was higher than CEA, CA153 and CA50 (all p < 0.05). MiR-421 in plasma had higher AUC value than AFP, CA153, CA211 and CA50 in the diagnosis of Pre (all p < 0.05), while specificity, accuracy and Youden index of miR-421 was only lower than CA211. The efficiency of miR-421 in the diagnosis of GC was significantly higher than that of CA211 and CA50, and it was significantly higher than CA153, CA211 and CA50 in the diagnosis of Pre (all p < 0.05). In addition, up-regulation of miR-421 occurred initially in precancerous gastric lesions as well as in the early stage of GC.

Conclusions
Overexpression of plasma miR-421 is a novel biomarker for the detection of precancerous lesions and early gastric cancer.
Comprehensive analysis of an lncRNA-miRNA-mRNA competing endogenous RNA network in pulpitis
Authors: Lei Fangcao , Zhang Han , Xie Xiaoli 
Published: June 2019

Background
Pulpitis is a common inflammatory disease that affects dental pulp. It is important to understand the molecular signals of inflammation and repair associated with this process. Increasing evidence has revealed that long noncoding RNAs (lncRNAs), via competitively sponging microRNAs (miRNAs), can act as competing endogenous RNAs (ceRNAs) to regulate inflammation and reparative responses. The aim of this study was to elucidate the potential roles of lncRNA, miRNA and messenger RNA (mRNA) ceRNA networks in pulpitis tissues compared to normal control tissues.

Methods
The oligo and limma packages were used to identify differentially expressed lncRNAs and mRNAs (DElncRNAs and DEmRNAs, respectively) based on expression profiles in two datasets, GSE92681 and GSE77459, from the Gene Expression Omnibus (GEO) database. Differentially expressed genes (DEGs) were further analyzed by Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses. Protein–protein interaction (PPI) networks and modules were established to screen hub genes using the Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) and the Molecular Complex Detection (MCODE) plugin for Cytoscape, respectively. Furthermore, an lncRNA-miRNA-mRNA-hub genes regulatory network was constructed to investigate mechanisms related to the progression and prognosis of pulpitis. Then, quantitative real-time polymerase chain reaction (qRT-PCR) was applied to verify critical lncRNAs that may significantly affect the pathogenesis in inflamed and normal human dental pulp.

Results
A total of 644 upregulated and 264 downregulated differentially expressed genes (DEGs) in pulpitis samples were identified from the GSE77459 dataset, while 8 up- and 19 downregulated probes associated with lncRNA were identified from the GSE92681 dataset. Protein–protein interaction (PPI) based on STRING analysis revealed a network of DEGs containing 4,929 edges and 623 nodes. Upon combined analysis of the constructed PPI network and the MCODE results, 10 hub genes, including IL6, IL8, PTPRC, IL1B, TLR2, ITGAM, CCL2, PIK3CG, ICAM1, and PIK3CD, were detected in the network. Next, a ceRNA regulatory relationship consisting of one lncRNA (PVT1), one miRNA (hsa-miR-455-5p) and two mRNAs (SOCS3 and PLXNC1) was established. Then, we constructed the network in which the regulatory relationship between ceRNA and hub genes was summarized. Finally, our qRT-PCR results confirmed significantly higher levels of PVT1 transcript in inflamed pulp than in normal pulp tissues (p = 0.03).

Conclusion
Our study identified a novel lncRNA-mediated ceRNA regulatory mechanisms in the pathogenesis of pulpitis.