bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proton pump inhibitors - possible side effects of long-term therapy: a review
Authors: Kowalewski Jan , Bęben Damian , Pyc Grzegorz , Kowalewski Łukasz 
Published: December 2024

Introduction and purpose: Proton pump inhibitors (PPIs), which have been on the market for more than 30 years, are widely regarded as safe and effective medications. For this reason, they are very popular with both doctors and patients. PPIs find their use in the treatment of such ailments as gastroesophageal reflux, gastric ulcer disease or as a shielding therapy when taking non-steroidal anti-inflammatory drugs. Nevertheless, their long-term use may be associated with many side effects. The purpose of our review is to summarize the knowledge in the current medical literature on the possible complications of chronic use of PPIs.
The review is based on 30 articles from the most recent publications on chronic PPI treatment. Publications were searched for the words PPI chronic therapy, gastric cancer, omeprazole in PubMed databases. Articles from 2018-2024 represent 70% of all publications from the references.
A brief description of the state of knowledge: Although the use of PPIs in the short term is relatively safe, the number of people taking these drugs has increased significantly in recent years. They are prescribed not always as indicated, patients often take them for too long - this in turn leads to an increasing incidence of side effects. Some of them can permanently affect health and significantly reduce the comfort of life - such as kidney diseases, cardiovascular disorders or gastric cancer.
Summary: Considering the widespread availability and popularity of PPIs, it is important to adequately educate both patients and healthcare professionals of the possible side effects. It is crucial to use medications as prescribed, with an appropriate assessment of the risk-benefit ratio. It might result in reducing health care expenditures to deal with the consequences of IPP therapy.
Numerical simulation of coherent summation of laser beams in the presence of non-idealities in the dipole focusing system
Authors: Bulanov D. N. , Khazanov E. A. , Shaykin A. A. , Korzhimanov A. V. 
Published: December 2024

A programming library was developed, based on Stratton–Chu diffraction integrals for calculating reflected optical fields. Dipole-type focusing schemes with a tunable number of beams and mirror placements were studied, considering the influence of phase distortion and aberrations. The intensity above 3×1026W/cm2 was found theoretically attainable in a system of 12 beams of 50 PW each, with about 90% of that value realistically achievable.
Structural design and simulation of a MOEMS gyroscope based on subwavelength grating detection
Authors: Li RuoXi , Jia XinRui , Guo Shangzhou , Sun Wenqiang , Jin Li , Xie KunYang , Li MengWei 
Published: December 2024

A novel, to the best of our knowledge, out-of-plane microelectromechanical system (MOEMS) gyroscope based on Wood’s type anomaly utilizing a subwavelength grating pair has been proposed. Based on this anomalous diffraction phenomenon, tiny changes in the displacement of the nanostructured grating elements lead to a dramatic increase or decrease of the optical diffraction amplitude. With this special feature, this structure is ideal to measure the weak Coriolis force of an MOEMS gyroscope. A simulation model of the gyroscope has been developed, with results indicating that the structure achieves good modal matching and a structural sensitivity of 0.094 nm/°/s. Optimal parameters for the subwavelength grating pair are determined through optimization design, and a tolerance analysis is conducted on several grating parameters, resulting in an optical diffraction sensitivity of 10.4%/nm. Finally, a model of the MOEMS gyroscope system was implemented in the Simulink module. Utilizing parameter values obtained from calculations, simulations of the subwavelength grating-based gyroscope yielded a total sensitivity of 3.04 mV/°/s and a theoretical noise floor of 5.1×10−5°/s/Hz. These results provide a theoretical foundation for the design and fabrication of an MOEMS gyroscope featuring subwavelength gratings.
Toward tunable pixelated microwave metamaterial for multiple sensing
Authors: Shahzad A. , Ahmed S. , Naqvi Q. A. , Ibrahim Abdel-Baset M. A. , Choudhury Pankaj K. 
Published: December 2024

An investigation was made of a specially designed pixelated metamaterial, with the top metasurface comprising square pixels of SrTiO3 and graphene, deposited over an indium antimonide (InSb) layer, with the bottom substrate being the SiO2 dielectric medium. Beneath the bottom, a thin copper layer blocks transmission. Emphasizing the absorption characteristics, artificial tunability was explored in the GHz frequency range under the electric and/or magnetic bias as the external stimuli. Apart from the polarization-insensitive properties, nearly perfect absorption was noticed within the 42.5–58.0 GHz frequency range while considering the isotropic and anisotropic conditions of the InSb layer. The developed pixelated metasurface demonstrates temperature sensitivities of ≈0.37GHz/∘C for an initial temperature increase from −5∘C to 0°C, and ≈0.01GHz/∘C as the temperature rises from 20°C to 25°C under isotropic conditions. Additionally, a maximum magnetic field sensitivity of around 6 GHz/T was observed for the anisotropic case. The findings demonstrate the versatility and potential of the proposed metamaterial for multi-functional sensing applications in the GHz range, particularly within the V-band, owing to its exceptional performance under varying thermal, electrical, and magnetic environments. The novelty of this work lies in the unique material combination, design robustness, and exploration of both the isotropic and anisotropic conditions, enabling tunable, polarization-insensitive high-performance absorption in the GHz range for advanced reconfigurable sensing and communication applications.
Time as a significant factor in the release of potassium from lithium heparin plasma and serum
Authors: Reuter Tom , Müller Michael , Stelter Felix , Durner Jürgen , Kramer Jan 
Published: December 2024

Objectives
In most countries the majority of patients are in outpatient care. In difference to hospitalized patients, their blood samples often take hours after collection to centrifugation. The study investigates the release of potassium and the development of pseudohyperkalemia in lithium heparin (Li-Hep) and serum blood collection tubes over time.

Methods
From 201 donors 4 serum and 4 Li-Hep blood collection tubes were taken each. After 0.5, 4, 6 and 8h whole blood was centrifuged, and potassium levels were determined. To simulate the preanalytic conditions, the samples with a storage time >0.5h were shaken on a standard shaker for 1h and stored at 4–8°C for the remaining time.

Results
Over time, significant more potassium was released before centrifugation from the Li-Hep plasma than from serum (1.21 vs 0.94 mmol/L). After 6h, the two groups were no longer highly statistically significantly different (potassium mean: 5.01 mmol/L in serum group, 4.92 mmol/L in Li-Hep group). In the Li-Hep group 164 donors developed a pseudohyperkalemia after 8h, compared to 76 in the serum group.

Significance
The decision as to which material is best suited should not only be based on which value comes closest to the physiological situation immediately after blood collection. The subsequent preanalytic circumstances must also be considered. Serum tubes appear to be at least as suitable for potassium determination as Li-Hep tubes. In terms of patient blood management, serum provides the possibility of performing a wider range of analyses in the outpatient setting.
Thinking outside the shoulder: A systematic review and metanalysis of kinetic chain characteristics in non-athletes with shoulder pain
Authors: Fonseca Fialho Hilmaynne Renaly , Gava Vander , Fonseca Romário Nóbrega Santos , Kamonseki Danilo Harudy , Barbosa Germanna Medeiros 
Published: December 2024

Introduction
The kinetic chain is important in the proximal-distal energy transfer along body segments. Although biomechanical impairments in components of the kinetic chain have already been reported in athletes with shoulder pain, such investigations in non-athlete individuals have not yet been synthesized.

Objective
To systematically review the literature and analyze the quality of evidence on the characteristics of the kinetic chain of non-athletes with shoulder pain compared to asymptomatic individuals.

Methods
Studies published until February 2024 (without language restrictions) that quantitatively assessed outcomes related to the kinetic chain of non-athlete individuals were searched in five databases (MEDLINE, CINAHL, Web of Science, EMBASE, and SCOPUS). The risk of bias and quality of evidence were analyzed using the Joanna Briggs Institute Critical Appraisal Tool for Analytical Cross-Sectional Studies and the Grading of Recommendations, Assessment, Development, and Evaluation approach, respectively. To summarize the findings, meta-analyses with random-effects models were performed.

Results
Six cross-sectional studies (n = 562 [282 with shoulder pain], mean age = 48.7 ± 8.1 years) with low risk of bias were included in this review. Very low-quality evidence suggests that individuals with shoulder pain may present a lower active range of motion and muscular endurance/strength in the cervical spine, thoracolumbar region, and hip, as well as deficits in neuromuscular control of the lower extremities. Findings related to thoracic spine posture were conflicting and no differences were found in cervical spine isometric muscular strength between individuals with and without shoulder pain.

Conclusion
Individuals with shoulder pain may present alterations in active mobility, muscular endurance, and neuromuscular control in kinetic chain segments. These findings suggest that broader physical assessments considering components of the kinetic chain may be clinically relevant in this population. However, based on the very low quality of evidence, the findings of this review should be interpreted with caution.
Identification of cuproptosis-related genes in septic shock based on bioinformatic analysis
Authors: Zhao Jintong , Zhang Meng , Wang Ying , He Feifei , Zhang Qiang 
Published: December 2024

Background
Septic shock is a life-threatening condition characterized by a failure of organ systems and a high mortality rate. Cuproptosis is a new form of cell death that is triggered by copper overload. However, the relationship between cuproptosis-related genes and septic shock remains unclear.

Methods
The GSE26440 dataset from the GEO database was used to screen differentially expressed genes (DEGs) between control and septic shock samples. Additionally, hub genes related to the progression of septic shock and cuproptosis were screened by Venn analysis. RT-qPCR was utilized to validate the expression of hub genes in peripheral blood lymphocytes from septic shock patients and healthy controls. Next, functional analysis and immune cells infiltration were performed.

Results
SLC31A1 and MTF1 levels were obviously elevated and LIAS and LIPT1 levels were downregulated in septic shock samples, compared to normal controls. The diagnostic values of the four genes were confirmed with receiver operating characteristic (ROC) curves. Additionally, SLC31A1 and MTF1 showed a positive correlation with natural killer cells and LIAS and LIPT1 exhibited a positive correlation with CD8+ T cells. Furthermore, compared to low-level groups, MAPK signaling was activated in the high-SLC31A1 level group, VEGF signaling was activated in the high-MTF1 level group and lipoic acid metabolism was activated in high-LIAS and high-LIPT1 level groups.

Conclusion
This study demonstrates that SLC31A1, MTF1, LIAS, and LIPT1 are dysregulated in septic shock samples, and these genes exhibit potential diagnostic efficacy in septic shock, suggesting that these genes may be potential biomarkers for the diagnosis of septic shock.
Os desafios para uma gestão democrática nas escolas públicas brasileiras.
Authors: Nunes Silva Brito Eugênio , Vilácio Pereira da Silva Magno , Marlene de Souza Margarete , Rocha Tameirão Cinthya 
Published: December 2024

Conforme legislação brasileira, a gestão democrática nas escolas públicas brasileiras baseia-se no princípio democrático, isso implica abrir espaço para discussão, aspecto fundamental para fortalecimento das relações sociais em uma sociedade multicultural. Compreende-se que, a construção da gestão democrática na escola abre espaço para a discussão e reflexão nas comunidades interna e externa à escola influenciando o desenvolvimento participativo em projetos da escola, pois busca a qualidade e a democracia no ensino. Este artigo tem como objetivo principal discutir os desafios que impedem a concretização de uma gestão democrática, a partir de uma revisão da literatura. Como problema norteador dessa pesquisa buscou-se compreender a gestão democrática escolar e os empecilhos existentes que impedem a concretização de uma abertura de espaço para a discussão e instauração de um processo democrático em que as comunidades interna e externa à escola participem do processo de construção dos projetos, de forma a buscar pela qualidade e democracia no ensino. Alguns artigos presentes na literatura que discutem sobre o tema, colaboraram para as discussões levantadas nesta pesquisa demonstrando a importância de uma gestão escolar democrática, com a construção do projeto político pedagógico idealizado de forma democrática e que se apoie no desenvolvimento de uma consciência crítica, que envolva as pessoas da comunidade interna e externa à escola. A pesquisa realizada aponta que ainda coexistem distintos modelos de gestão, ou mesmo que a gestão democrática, como um processo, ainda pode ser encontrada em distintos estágios dentre as escolas e realidades observadas.
Asymptotic model for the propagation of surface waves on a rotating magnetoelastic half-space
Authors: Mubaraki Ali M. 
Published: December 2024

Abstract
This article is focused on deriving the approximate model for surface wave propagation on an elastic isotropic half-plane under the effects of the rotation and magnetic field along with the prescribed vertical and tangential face loads. The method of study depends on the slow time perturbation of the prevalent demonstration for the Rayleigh wave eigen solutions through harmonic functions. A perturbed pseudo-hyperbolic equation on the interface of the media is subsequently derived, governing the propagation of the surface wave. The established asymptotic formulation is tested by comparison with the exact secular equation. In the absence of the magnetic field, the specific value of Poisson’s ratio,

ν
=
0.25

\nu =0.25

, is highlighted, where the rotational effect vanishes at the leading order.
Preparation of high-activity mineral powder from coal gangue through thermal and chemical activation
Authors: Zhang Wuju , Long Hailin , Zhu Deqing , Pan Jian , Li Siwei , Guo Zhengqi 
Published: December 2024

Abstract
This study focuses on enhancing the cementitious activity of coal gangue through a two-step process involving thermal activation followed by chemical alkali excitation. The coal gangue was first treated via a self-heating sintering decarbonization process, which effectively increased its reactivity without the need for additional solid fuel. Following thermal activation, chemical activation was performed using activators such as hydrated lime and lithium silicate to further improve the reactivity of the decarbonized coal gangue. The effectiveness of combining ground granulated blast furnace slag (GGBS) with the activated coal gangue was also evaluated. Results revealed that incorporating 35–45 % GGBS with activated coal gangue significantly enhanced both early and long-term strength, achieving an activity index exceeding 100 % under optimal conditions. The addition of 5 % hydrated lime significantly increased the 28-day activity index of the mineral powder to 82.7 %. Optimization experiments showed that reducing the content of decarbonized coal gangue and fine-tuning the proportions of activators further enhanced the overall activity index, reaching up to 103.7 %. This study provides a comprehensive approach to improving the resource utilization of coal gangue through integrated thermal and chemical activation, paving the way for its application in sustainable construction materials.
Cross-dataset micro-expression identification based on facial ROIs contribution quantification
Authors: Yu Kun , Guo Chunfeng 
Published: December 2024

Abstract
In this work, we propose a novel cross-dataset micro-expression identification method based on facial regions of interest contribution quantification, where the training samples are from the source dataset and the test samples are from the target dataset. Specifically, a micro-expression video clip (i.e., a sample) is first sampled at intervals to capture an image sequence consisting of multiple consecutive video frames. Then, locate and crop the facial area in the image frame, and perform facial landmark detection on the cropped area. Next calculate the optical-flow field of the image sequence, and extract the improved Main Directional Mean Optical-flow feature. Finally, the learned group sparse model is used as the classifier to predict the label information of the unmarked target samples, so as to complete the category recognition of micro-expressions. Extensive cross-dataset comparative experiments on four spontaneous micro-expression datasets, CASME, CASME II, SMIC-HS, and SAMM, show that the recognition strategy proposed in this work is effective. Compared with several other advanced recognition methods, our method has better cross-dataset recognition performance, not only the classification accuracy is higher, but also the classification stability is better when faced with different target datasets and different micro-expression categories. It can be applied in many fields such as clinical diagnosis, interrogation, negotiation, and national security.
Management of endometriosis: a call to multidisciplinary approach
Authors: Duncan Jordann-Mishael , Delara Ritchie , Ranieri Gina , Wasson Megan 
Published: December 2024

Abstract
Endometriosis is defined as the presence of endometrial-like glands and stroma outside of the uterus. There are three types of endometriotic lesions: superficial or peritoneal endometriosis, ovarian endometrioma, and deep infiltrating disease. Endometriosis not only occurs in the pelvis but also can be found in extrapelvic sites such as the gastrointestinal tract, upper abdominal viscera, genitourinary tract, abdominal wall, diaphragm, and thoracic cavity. After thorough history and physical examination is performed, imaging, such as ultrasound or magnetic resonance imaging (MRI), should be obtained if there is high suspicion for deep-infiltrating endometriosis to better assess visceral involvement. Endometriosis can be suspected based on symptoms, physical examination findings, and imaging. However, a definitive diagnosis requires histopathologic confirmation. Treatment options include expectant, medical, and surgical management. Endometriosis is largely a quality-of-life issue, and treatment should be tailored accordingly with empiric medical therapy frequently utilized. Medical management focuses on symptom improvement. Surgical management with excision of endometriosis is preferred over ablation or fulguration of endometriotic lesions. In the case of deep or extrapelvic endometriosis, treatment with a multidisciplinary team with experience in the treatment of advanced-stage endometriosis is essential to minimizing morbidity and increasing long-term success.
Investigating the acoustic fidelity of vowels across remote recording methods
Authors: Oganyan Marina , Levow Gina-Anne , Squizzero Robert , Ahn Emily P. , Ng Sara , Deaton Ella , Wright Richard A. 
Published: December 2024

Abstract
Our study tests the acoustic fidelity of remote recordings, using a large variety of stimuli and recording environments. Remote recordings support crucial uses like reaching isolated populations and more speakers; however, it is important to be aware of any limitations therein. A 188-word list was constructed from each English consonant followed by each vowel. Words recorded by one male and one female speaker in a sound-attenuated booth were input for test recordings. Stimuli were played over an electronic speaker and recorded on six devices across five operating systems, four teleconferencing platforms, and two browsers, using internal and external microphones, a more extensive set than has been analyzed in prior research. Acoustic analysis investigates the impact of these recording configurations on fundamental frequency, loudness, and vowel formant measures. Across recording conditions, browser choice had less effect on the different vowel measures, while choice of hardware resulted in a greater number of significant differences and greater variability within and across conditions. Recording configuration effects were observed to exert different impacts across vowels and speakers, resulting in inconsistent perturbations. These results highlight the need for careful selection and detailed documentation of all recording configurations.
Classifying offensive language in Arabic: a novel taxonomy and dataset
Authors: Liebeskind Chaya , Afawi Ali , Litvak Marina , Vanetik Natalia 
Published: December 2024

Abstract
This paper presents a streamlined taxonomy for categorizing offensive language in Arabic, specifically Modern Standard Arabic (MSA) and the Levantine dialect. Addressing a gap in the existing literature, which has mainly focused on Indo-European languages, our taxonomy divides offensive language into seven levels (six explicit and one implicit). We adapted our framework from the simplified offensive language (SOL) taxonomy by (Lewandowska-Tomaszczyk, Barbara, Slavko Žitnik, Anna Bączkowska, Chaya Liebeskind, Jelena Mitrovic & Giedre Valunaite Oleškeviciente. 2021a. Lod-connected offensive language ontology and tagset enrichment. In Shubert R. Carvalho & Renato R. Souza (eds.), Proceedings of the workshops and tutorials held at ldk 2021 co-located with the 3rd language, data and knowledge conference, Vol. 3064, 135–150. CEUR Workshop Proceedings), customizing it to reflect the unique linguistic and cultural nuances of Arabic. To validate this taxonomy, we created a new dataset from various social media platforms, primarily focusing on Twitter. This dataset was manually curated by human annotators and is described in detail within the paper, serving as both a validation tool for our taxonomy and a foundation for future research on offensive language detection in Arabic. Initial analysis of the dataset reveals complex patterns of offensive expressions in MSA and Levantine Arabic, underscoring the need to account for linguistic and cultural variations in studying online abuse. Our taxonomy and dataset are vital for advancing research in Arabic sociocultural studies, natural language processing, and linguistic analysis, and contribute to the study of low-resource languages.