bluuebunny/crossref_metadata_2025_split huggingface dataset:
Droplet aerosol dissemination of carbapenem-resistant Acinetobacter baumannii surrounding ventilated patients
Authors: Mousa Madelyn , Schwartz David , Carmeli Yehuda , Nutman Amir 
Published: February 2019

AbstractWe measured droplet aerosol dissemination of carbapenem-resistant Acinetobacter baumannii (CRAB) by sampling air surrounding 10 ventilated patients with CRAB isolated in sputum. Over 70 hours, we sampled 252,000 L of air; CRAB was detected in 39,600 L (16%). CRAB growth was higher during patient care, notably suctioning and sheet changing.
Automated data mining of the electronic health record for investigation of healthcare-associated outbreaks
Authors: Sundermann Alexander J. , Miller James K. , Marsh Jane W. , Saul Melissa I. , Shutt Kathleen A. , Pacey Marissa , Mustapha Mustapha M. , Ayres Ashley , Pasculle A. William , Chen Jieshi , Snyder Graham M. , Dubrawski Artur W. , Harrison Lee H. 
Published: February 2019

AbstractBackground:Identifying routes of transmission among hospitalized patients during a healthcare-associated outbreak can be tedious, particularly among patients with complex hospital stays and multiple exposures. Data mining of the electronic health record (EHR) has the potential to rapidly identify common exposures among patients suspected of being part of an outbreak.Methods:We retrospectively analyzed 9 hospital outbreaks that occurred during 2011–2016 and that had previously been characterized both according to transmission route and by molecular characterization of the bacterial isolates. We determined (1) the ability of data mining of the EHR to identify the correct route of transmission, (2) how early the correct route was identified during the timeline of the outbreak, and (3) how many cases in the outbreaks could have been prevented had the system been running in real time.Results:Correct routes were identified for all outbreaks at the second patient, except for one outbreak involving >1 transmission route that was detected at the eighth patient. Up to 40 or 34 infections (78% or 66% of possible preventable infections, respectively) could have been prevented if data mining had been implemented in real time, assuming the initiation of an effective intervention within 7 or 14 days of identification of the transmission route, respectively.Conclusions:Data mining of the EHR was accurate for identifying routes of transmission among patients who were part of the outbreak. Prospective validation of this approach using routine whole-genome sequencing and data mining of the EHR for both outbreak detection and route attribution is ongoing.
Turbulence structures and statistics of a supersonic turbulent boundary layer subjected to concave surface curvature
Authors: Sun Mingbo , Sandham Neil D. , Hu Zhiwei 
Published: February 2019

Supersonic turbulent flows at Mach 2.7 over concave surfaces for two different radii of curvature were investigated and compared with a flat plate turbulent boundary layer using direct numerical simulations. The streamwise velocity reduces in the outer part of the boundary layer due to compression, while it increases near the wall due to curvature, with a higher shape factor for the concave cases. The near-wall spanwise streak spacing reduces compared to the flat plate, with large-scale streaks and turbulence amplification also observed. Streamwise velocity iso-surfaces and streamlines show the generation of Görtler-like vortices, consistent with significant centrifugal effects. Abundant small vortices are shown to be associated with large baroclinic production of vorticity that is caused by the density and pressure gradients that are associated with concave compression. Profiles of turbulent kinetic energy and turbulent Mach number exhibit a characteristic two-layer structure in the concave boundary layer cases. In the outer layer, turbulence is greatly amplified, whereas a local balance exists in the inner layer. Turbulent energy budget analysis shows that both production and dissipation increase near the concave wall, whereas in the outer part of the boundary layer, the production is increased and ultimately balanced by convection and turbulent transport.
Diurnal fluctuations of glacier surface velocity observed with terrestrial radar interferometry at Laohugou No. 12 Glacier, western Qilian mountains, China
Authors: LIU LIN , JIANG LIMING , SUN YONGLING , WANG HANSHENG , SUN YAFEI , XU HOUZE 
Published: February 2019

ABSTRACTMeasurements of short-interval variations in glacier surface velocity, which contribute to our understanding of ice motion mechanisms, remain scarce on the Tibetan Plateau. Here we present sub-hourly measurements of glacier surface motion variations at the terminus region of Laohugou No. 12 Glacier. Field observations were collected over 4 d in July 2015 from terrestrial radar interferometry. The observed glacier displacement time series are generally in agreement with the results measured by differential GPS and highlight that glacier surface velocity is characterized by clear diurnal fluctuations in the study period. During day-time hours, glacier flow speeds were higher than 3.0 mm h−1, whereas they were below 1.0 mm h−1 during night-time hours. The large diurnal fluctuations of glacier surface velocity indicate that variations in basal slip are the dominant motion mechanism. Moreover, a positive correlation (R = 0.82, P < 0.001) between air temperature and glacier surface velocity suggests that glacier motion variations are probably affected by changes in air temperature during the ablation season.
Postglacial wetland succession, carbon accumulation, and forest dynamics on the east coast of Vancouver Island, British Columbia, Canada
Authors: Lacourse Terri , Beer Kyle W. , Craig Kira B. , Canil Dante 
Published: February 2019

ABSTRACTPeatland development and carbon accumulation on the Pacific coast of Canada have received little attention in paleoecological studies, despite wetlands being common landscape features. Here, we present a multi–proxy paleoenvironmental study of an ombrotrophic bog in coastal British Columbia. Following decreases in relative sea level, the wetland was isolated from marine waters by 13,300 cal yr BP. Peat composition, non-pollen palynomorph, and C and N analyses demonstrate terrestrialization from an oligotrophic lake to a marsh by 11,600 cal yr BP, followed by development of a poor fen, and then a drier ombrotrophic bog by 8700 cal yr BP. Maximum carbon accumulation occurred during the early Holocene fen stage, when seasonal differences in insolation were amplified. This highlights the importance of seasonality in constraining peatland carbon sequestration by enhancing productivity during summer and reducing decomposition during winter. Pollen analysis shows thatPinus contortadominated regional forests by 14,000 cal yr BP. Warm and relatively dry summers in the early Holocene allowedPseudotsuga menziesiito dominate lowland forests 11,200–7000 cal yr BP.Tsuga heterophyllaandP. menziesiiformed coniferous forest in the mid- and late Holocene. Tephra matching the mid-Holocene Glacier Peak–Dusty Creek assemblage provides evidence of its most northwesterly occurrence to date.
Distinct temporal brain dynamics in bipolar disorder and schizophrenia during emotion regulation
Authors: Zhang Liwen , Ai Hui , Opmeer Esther M. , Marsman Jan-Bernard C. , van der Meer Lisette , Ruhé Henricus G. , Aleman André , van Tol Marie-José 
Published: February 2019

AbstractBackgroundDisturbances in emotion regulation (ER) are characteristic of both patients with bipolar disorder (BD) and schizophrenia (SZ). We investigated the temporal dynamics of brain activation during cognitive ER in BD and SZ to understand the contribution of temporal characteristics of disturbed ER to their unique and shared symptomatology.MethodForty-six participants performed an ER-task (BD,n= 15; SZ,n= 16; controls,n= 15) during functional magnetic resonance imaging, in which they were instructed to use cognitive reappraisal techniques to regulate their emotional responses. Finite impulse response modeling was applied to estimate the temporal dynamics of brain responses during cognitive reappraisal (v.passive attending) of negative pictures. Group, time, and group × time effects were tested using multivariate modeling.ResultsWe observed a group × time interaction during ER in the ventrolateral prefrontal cortex (VLPFC), supplementary motor area (SMA) and inferior occipital gyrus. Patients with SZ demonstrated initial hyper-activation of the VLPFC and SMA activation that was not sustained in later regulatory phases. Response profiles in the inferior occipital gyrus in SZ showed abnormal activation in the later phases of regulation. BD-patients showed general blunted responsivity in these regions.ConclusionsThese results suggest that ER-disturbances in SZ are characterized by an inefficient initialization and failure to sustain regulatory control, whereas in BD, a failure to recruit regulatory resources may represent initial deficits in formulating adequate representations of the regulatory needs. This may help to further understand how ER-disturbances give rise to symptomatology of BD and SZ.
Characteristics of patients with motor functional neurological disorder in a large UK mental health service: a case–control study
Authors: O'Connell N. , Nicholson T. R. , Wessely S. , David A. S. 
Published: February 2019

AbstractBackgroundFunctional neurological disorder (FND), previously known as conversion disorder, is common and often results in substantial distress and disability. Previous research lacks large sample sizes and clinical surveys are most commonly derived from neurological settings, limiting our understanding of the disorder and its associations in other contexts. We sought to address this by analysing a large anonymised electronic psychiatric health record dataset.MethodsData were obtained from 322 patients in the South London and Maudsley NHS Foundation Trust (SLaM) who had an ICD-10 diagnosis of motor FND (mFND) (limb weakness or disorders of movement or gait) between 1 January 2006 and 31 December 2016. Data were collected on a range of socio-demographic and clinical factors and compared to 644 psychiatric control patients from the same register.ResultsWeakness was the most commonly occurring functional symptom. mFND patients were more likely to be female, British, married, employed pre-morbidly, to have a carer and a physical health condition, but less likely to have had an inpatient psychiatric admission or to receive benefits. No differences in self-reported sexual or physical abuse rates were observed between groups, although mFND patients were more likely to experience life events linked to inter-personal difficulties.ConclusionsmFND patients have distinct demographic characteristics compared with psychiatric controls. Experiences of abuse appear to be equally prevalent across psychiatric patient groups. This study establishes the socio-demographic and life experience profile of this understudied patient group and may be used to guide future therapeutic interventions designed specifically for mFND.
Maintaining the ‘caring self’ and working relationships: a critically informed analysis of meaning-construction among paid companions in long-term residential care
Authors: Funk Laura M. , Outcalt Linda 
Published: February 2019

AbstractIn Canadian residential long-term care, paid companion services are increasingly viewed as helping to meet older adults’ psycho-social needs. Complementing the critique of these services from a political economy perspective, analyses of companions’ talk about their work can illuminate not only why companions stay in devalued and often invisible work, but also how social assumptions and circulating narratives about nursing homes and older adults are implicated in this process. In this article, we draw on in-depth analyses of interviews with both companions and organisational representatives. We interpret companions’ accounts in relation to their need to justify the necessity for their work to their employers (families), to nurture good relationships with the facilities in which they work, and to maintain a sense of identity as a responsible, conscientious and ‘caring self’. In this way, these precarious workers inadvertently reproduce dominant narratives, including those that stigmatise dementia and residential care, and facilitate the privatisation of person-centred, relational care. Organisational representatives generally reproduce similar assumptions about care responsibilities, in a context in which facilities are increasingly challenged to meet a range of resident needs. Discussion highlights tensions around responsibility for psycho-social care in nursing homes, highlighting organisational vested interests in avoiding risk and downloading responsibilities to families and to private, independent and temporary workers.
Mothers' and fathers' self-regulation capacity, dysfunctional attributions and hostile parenting during early adolescence: A process-oriented approach
Authors: Sturge-Apple Melissa L. , Li Zhi , Martin Meredith J. , Jones-Gordils Hannah R. , Davies Patrick T. 
Published: February 2019

AbstractThe parent-child relationship undergoes substantial reorganization over the transition to adolescence. Navigating this change is a challenge for parents because teens desire more behavioral autonomy as well as input in decision-making processes. Although it has been demonstrated that changes in parental socialization approaches facilitates adolescent adjustment, very little work has been devoted to understanding the underlying mechanisms supporting parents’ abilities to adjust caregiving during this period. Guided by self-regulation models of parenting, the present study examined how parental physiological and cognitive regulatory capacities were associated with hostile and insensitive parent conflict behavior over time. From a process-oriented perspective, we tested the explanatory role of parents’ dysfunctional child-oriented attributions in this association. A sample of 193 fathers, mothers, and their early adolescent (ages 12–14) participated in laboratory-based research assessments spaced approximately 1 year apart. Parental physiological regulation was measured using square root of the mean of successive differences during a conflict task; cognitive regulation was indicated by set-shifting capacity. Results showed that parental difficulties in vagal regulation during parent-adolescent conflict were associated with increased hostile conflict behavior over time; however, greater set-shifting capacity moderated this association for fathers only. In turn, father's dysfunctional attributions regarding adolescent behavior mediated the moderating effect. The results highlight how models of self-regulation and social cognition may explain the determinants of hostile parenting with differential implications for fathers during adolescence.
Learning English through out-of-school exposure. Which levels of language proficiency are attained and which types of input are important?
Authors: De Wilde Vanessa , Brysbaert Marc , Eyckmans June 
Published: February 2019

AbstractIn this study we examined the level of English proficiency children can obtain through out-of-school exposure in informal contexts prior to English classroom instruction. The second aim was to determine the input types that fuel children's informal language acquisition. Language learning was investigated in 780 Dutch-speaking children (aged 10–12), who were tested on their English receptive vocabulary knowledge, listening, speaking, reading and writing skills. Information about learner characteristics and out-of-school English exposure was gathered using questionnaires. The results show large language gains for a substantial number of children but also considerable individual differences. The most beneficial types of input were gaming, use of social media and speaking. These input types are interactive and multimodal and they involve language production. We also found that the various language tests largely measure the same proficiency component.
Cognitive control in bilinguals: Effects of language experience and individual variability
Authors: Bonfieni Michela , Branigan Holly P. , Pickering Martin J. , Sorace Antonella 
Published: February 2019

AbstractWe report a study that investigated executive functions in four groups of participants that varied in bilingual language experience, using a task that measured two theoretically motivated mechanisms of cognitive control (proactive and reactive control). Analyses of accuracy based on aggregated measures suggested an advantage in early highly proficient bilinguals over late passive bilinguals. However, when we factored in individual variability using mixed-model regression with a full random effect structure, we only found a marginal effect of language experience. Our results emphasise the importance of including individual variability when studying bilingualism, and highlight a fundamental consideration in research on the relation between language and attention – namely, the need for a theory-driven approach to measuring cognitive control through laboratory tasks.
Building a Library of Simulated Atom Probe Data for Different Crystal Structures and Tip Orientations Using TAPSim
Authors: Kühbach Markus , Breen Andrew , Herbig Michael , Gault Baptiste 
Published: February 2019

AbstractThe process of building an open source library of simulated field desorption maps for differently oriented synthetic tips of the face-centered cubic, body-centered cubic, and hexagonal-close-packed crystal structures using the open source software TAPSim is reported. Specifically, the field evaporation of a total set of 4 × 101 single-crystalline tips was simulated. Their lattices were oriented randomly to sample economically the fundamental zone of crystal orientations. Such data are intended to facilitate the interpretation of low-density zone lines and poles that are observed on detector hit maps during Atom Probe Tomography (APT) experiments. The datasets and corresponding tools have been made publicly available to the APT community in an effort to provide better access to simulated atom probe datasets. In addition, a computational performance analysis was conducted, from which recommendations are made as to which key tasks should be optimized in the future to improve the parallel efficiency of TAPSim.
Quantitative Determination of How Growth Conditions Affect the 3D Composition of InGaAs Nanowires
Authors: Qu Jiangtao , Chen Hansheng , Khan Mansoor , Yun Fan , Cui Xiangyuan , Ringer Simon P. , Cairney Julie M. , Zheng Rongkun 
Published: February 2019

AbstractCovering a broad optical spectrum, ternary InxGa1−xAs nanowires, grown by bottom-up methods, have been receiving increasing attention due to the tunability of the bandgap via In composition modulation. However, inadequate knowledge about the correlation between growth and properties restricts our ability to take advantage of this phenomenon for optoelectronic applications. Here, three different InGaAs nanowires were grown under different experimental conditions and atom probe tomography was used to quantify their composition, allowing the direct observation of the nanowire composition associated with the different growth conditions.
A hybrid approach for head and neck cancer using online image guidance and offline adaptive radiotherapy planning
Authors: Srivastava Roopam , Sharma P.K. , Das K.J. Maria , Manjhi Jayanand 
Published: February 2019

AbstractBackgroundThis is a prospective study to evaluate the dosimetric benefits of treatment plan adaptation for patients who had undergone repeat computed tomography (ReCT)and re-planning due to treatment-induced anatomical changes during radiotherapy.Materials and MethodsThis study involved five head and neck cancer patients who had their treatment plan modified, based on weekly thrice imaging protocol. Impact of mid-course imaging was assessed in patients using ReCT and cone beam computed tomography (CBCT)-based dose verification. Patients were imaged, apart from their initial CT, during the course of their radiation therapy with a ReCT and on board imager CBCT (Varian Medical Systems Inc., Palo Alto, CA, USA). Each CBCT/CT series was rigidly registered to the initial CT in the treatment planning system Eclipse (Varian Medical Systems Inc.) using bony landmarks. The structures were copied to the current CBCT/CT series and, where needed, manually edited slicewise. The dose distribution from the treatment plan was viewed as of the current anatomy by applying the treatment plan the CBCT/CT series, and studying the corresponding dose–volume histograms for organs at risk doses.ResultsThe reduction of parotid volumes due to weight loss was observed in all patients, which means an increase in predicted mean doses of parotid when initial CT plan was re-calculated on ReCT and CBCT (Table 1). This explains the necessity of adaptive planning. The predicted mean dose of parotid glands was increased and constraints to spinal cord and skin were exceeded, so re-planning was performed.ConclusionsThe CBCT is a useful tool to view anatomic changes in patients and get an estimate of their impact on dose distribution. Re-planning based on imaging in head and neck patients during the course of radiotherapy is mandatory to reduce side effects.
Cover crop species affect mycorrhizae-mediated nutrient uptake and pest resistance in maize
Authors: Murrell Ebony G. , Ray Swayamjit , Lemmon Mary E. , Luthe Dawn S. , Kaye Jason P. 
Published: February 2019

AbstractArbuscular mycorrhizal fungi (AMF) can increase plant nutrient uptake and chemical defense production, both of which can improve plants’ ability to resist insect herbivory. Cover crops—non-commercial species planted in between cash crops in a crop rotation—can naturally alter both soil nutrients and AMF. We tested whether different cover crop species alter AMF colonization, plant nutrient status and plant–insect interactions in a subsequent maize crop. Cover crop species were either non-mycorrhizal, non-leguminous (canola, forage radish), mycorrhizal non-leguminous (cereal rye, oats), mycorrhizal leguminous (clover, pea) or absent (fallow). We measured the cascading consequences of cover crop treatment on maize root AMF colonization, maize growth and performance of an herbivorous insect (European corn borer) feeding on the maize. Maize AMF colonization was greater in plots previously planted with mycorrhizal (rye, oats) than non-mycorrhizal (canola, radish) cover crops or no cover crop (fallow). AMF colonization was linked to increased plant phosphorous and nitrogen, and maize growth increased with low plant N:P. Induced jasmonic acid pathway plant defenses increased with increasing maize growth and AMF colonization. European corn borer survivorship decreased with lower plant N:P, and insect development rate decreased with increased induced plant defenses. Our data describe a cascade in which cover crop species selection can increase or decrease mycorrhizal colonization of subsequent maize crop roots, which in turn impacts phosphorus uptake and may affect herbivory resistance in the maize. These results suggest that farmers could select cover crop species to manage nutrient uptake and pest resistance, in order to amend or limit fertilizer and pesticide use.
Is competition among cooperative banks a negative sum game?
Authors: Coccorese Paolo , Ferri Giovanni 
Published: February 2019

AbstractDoes ‘inner competition’ – rivalry among network members – worsen performance in a network of cooperative banks? By weakening the functionality of the network, inner competition might, in fact, endanger network-dependent scale economies. Testing our hypothesis on Italy's network of mutual cooperative banks (Banche di Credito Cooperativo – BCCs), we find a worsening of performance of both incumbents and (even more) aggressors when BCCs compete among themselves. However, the worsening is mild when BCCs compete with comparable non-mutual banks external to the BCC network. We conclude that inner competition among cooperative banks is a negative sum game and, thus, limiting it would be desirable to preserve the stability of cooperative banking networks.