bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digital Broadband and Open Innovation: First Insights in Information Technologies Sector.
Authors: Mejía-Trejo Juan 
Published: March 2018

Purpose. The study is aimed to disclose how Digital Broadband (DBD) is affecting the practice of Open Innovation (OIN) in the Information Technologies Sector of Metropolitan Zone of Guadalajara, Mexico (ITSZMG) to achieve a model, for the improvement of relationships.Methodology. It is a descriptive, exploratory, correlational, cross-sectional, qualitative-quantitative research. As a qualitative study, it is based on a deep literature review after which, we used Delphi Panel with Analytic Hierarchy Process (AHP), determining our main factors: DBD (1 factor/ 6 variables/43 indicators) and OIN (3 factors/23 variables/161 indicators) in a questionnaire Likert scale, involving 600 ITSZMG specialists at 200 SMEs. The survey was on the period of September-December 2016. As a quantitative study, we applied Confirmatory Factor Analysis using EQS 6.2 software.-The value of this study, is to propose a generalized model involving the relationship between DBD-OIN for ITSZMG, and identify the underlying variables and their relationships to make suggestions about how to be more innovative, among the firms in the sector.-Final results: 5/6 DBD variables have significant positive effect on 18/23 OIN variables.This implies opportunities to develop the model.-Conclusions: We obtained an empirical model capable of identifying its own DBD-OIN relationships in order to be, a more innovative firm in the ITSZMG.
Trends in the prevalence of hypertension among children and adolescents during 2000-2014.
Authors: Vergara Castañeda Arely , Zavaleta Rodríguez Avril , Ayala Moreno Rosario , Martino Roaro Laura 
Published: March 2018

Hypertension has been cited as a major risk factor of morbidity and mortality related to cardiovascular diseases and it is considered a public health problem worldwide. There is a lack of information regarding the real prevalence of hypertension among children and adolescents because blood pressure assessment is not considered part of the routine clinical assessment in this population.The aim of this study was analyze the reported prevalence of hypertension in children and adolescents according gender and nutritional status during the period 2000-2014.Methods: A systematic review focused on the assessment of high blood pressure was conducted. Only original articles were selected on the basis of strict inclusion and details and reviewed by pairs. 98 studies met the inclusion criteria. Computerized searches were completed using multiple databases.Results: Nutritional status strongly influences whether children are more likely to have hypertension. However this condition is not the same for overweight children in the United States that have less hypertension than obese children or the adolescents in Asia that the same effect occur. In the case of sex, it was observed that boys in most of the regions are more likely to have hypertension, however this change in the United States and in Africa where girls suffer more of hypertension. According with the age, there are more cases of hypertension among adolescents than in children, where Latin America reported the highest level of hypertension.Conclusion: The data indicated that despite differences between regions, childhood hypertension has increased in the course of 14 years and it is higher among boys (36.69%) than girls (35.87%), and is also affect by the nutritional status of individuals (37.29% normal weight, 49.49% obese and 68.55% overweight). The reporting of prevalence among children and adolescents around the world need to be improved considerably in order to diminish the inconsistences.
Plasma Malondialdehid and Histopatology Healing Score Differences in Incised Old and Young Mice Zinc with Zinc Administration
Authors: Aryantie Moniq W. , Monica Rizqy D. , Rezano Andri , Adi Sudigdo , Rizki Kiki A. , Zuhairini Yenni 
Published: March 2018

Free radical plays role in wound healing. This study was conducted to determinedifferences in level of plasma malondialdehyde (MDA), and histopathological score of woundhealing by administering zinc in old and young mice. We used 24 old mice and 24 young miceincision wound model, randomized into two groups, with and without zinc administration. Wefound plasma MDA level was lower in old mice with zinc administration but not statisticallysignificant. The plasma MDA level was significantly higher by administering zinc in young mice(p=0.004). The plasma MDA level of young mice was higher than old mice in zincadministration group (p=0.010). Reepitelialization, inflammatory cells, fibroblasts andangiogenesis did not differ by administering zinc both in old mice and young mice.Reepitelialization, inflammatory cells and angiogenesis did not differ between old and youngmice in mice that were given zinc; while fibroblast of young mice is more than old mice(p=0.010). We concluded plasma MDA level is higher in young mice with zincadministration. Plasma MDA level in young mice is higher than old mice with zincadministration. Young mice with zinc administration have higher fibroblast than oldmice.Keywords: aging, free radical, histopathologic score, malondialdehid, wound healing, zinc
PENGEMBANGAN PERANGKAT LUNAK ANALISIS LINTAS TERBANG ROKET MULTI-STAGE (DEVELOPMENT OF TRAJECTORY ANALYSIS SOFTWARE FOR MULTI-STAGE ROCKET)
Authors: Eko Poetro Ridanto , I. Jenie Yazdi , Adhy Sasongko Rianto , Utama Satriya 
Published: March 2018

This paper discusses the development of a computer software for simulating and analyzing flight trajectory of rocket systems. Many aspects may influence the trajectory, such as those related to the internal characteristic of the system, those representing external or environmental influence, and also the ones corresponding to the procedures of the launching and the operation during its flight. The software is developed based on the mathematical equations representing the balance of forces and moments occur during the flight of a rocket. Some conditions related to rocket internal characteristic variation, external perturbance, and flight procedure/operation are represented as parameters variations of the mathematical equations used for computing the rocket system attitude and movement variables. The software, developed using MATLAB/ SIMULINK application, is then used for simulating and analyzing the flight trajectory of a multi-stage rocket in some flight conditions. At this development stage, as the simulation results show, the software can perform its function quite well to compute the system variables during each of its flight phases and display the information required for further analysis. In future development, some validation tests still need to be accomplished for ensuring the accuracy and validity of the method used in this software.
Keywords: Rocket, Flight Trajectory, Simulation
EVALUASI KINETIKA DEKOMPOSISI TERMAL PROPELAN KOMPOSIT AP/HTPB DENGAN METODE KISSINGER, FLYNN WALL OZAWA DAN COATS - REDFREN
Authors: Dewi Wiwiek Utami 
Published: March 2018

Decomposition of propellant Mechanism and kinetics have been investigated by using DTG/TA with three different methods: Kissinger, Flynn Wall Ozawa and Coats & Redfern. This research aims to determine decomposition kinetic parameters of LAPAN’s propellant. The propellants have different composition of Al and AP modal. RUM propellant consist of AP/HTPB. 450 propellant consists AP/HTPB/Al (bimodal). Meanwhile 1220 propellant consists of AP/HTPB/Al (trimoda). Thermal analysis takes place at 30 – 400oC and nitrogen atmosphere flow rate is 50 ml/min. The result according showed that propellant was decomposed by F1 mechanism (random nucleation with one nucleus on the individual particles). Activation energy of propellants are in range between 100.876 – 155.156 kJ/mol meanwhile pre-exponential factor are in range between 4.57 x 107 – 3.46 x 1012/min. Activation energy (E) as well as pre-exponential factor for 1220 propellant is the lowest among the others. AP trimodal application generates catalytic effect which decreases activation energy. 1220 propellant is easier to decompose (easier to react) than RUM and 450 propellant. AbstrakMekanisme dan kinetika dekomposisi propelan telah diinvestigasi menggunakan DTG/TA dengan tiga jenis metode yang berbeda yaitu Kissinger, Flynn Wall Ozawa dan Coats & Redfern. Penelitian ini bertujuan untuk mengetahui parameter kinetika dekomposisi propelan LAPAN. Propelan yang digunakan memiliki perbedaan komposisi Al dan jenis moda AP. Propelan RUM adalah propelan AP/HTPB. RX 450 adalah AP/HTPB/ Al (bimoda). Sementara itu, RX 1220 adalah AP/HTPB/ Al (trimoda). Pengujian termal berlangsung pada suhu 30 - 400oC dan atmosfer nitrogen berlaju alir 50 ml/menit. Hasil penelitian mengungkapkan bahwa semua jenis propelan terdekomposisi dengan mekanisme F1 (nukleasi acak dengan satu nukleus pada partikel individu). Energi aktivasi propelan berkisar antara 100,876 – 155,156 kJ/mol sementara faktor pre-eksponensial berkisar antara 4,57 x 107 – 3,46 x 1012/min. Energi aktivasi (E) dan faktor pre-eksponensial (A) RX 1220 adalah terendah dari ketiga sampel. Penggunaan jenis AP trimodul menciptakan efek katalitik yang menurunkan besarnya energi aktivasi. Propelan RX 1220 lebih mudah terdekomposisi (lebih mudah bereaksi) daripada propelan RUM dan RX 450.
PERANCANGAN AUTOPILOT LATERAL-DIREKSIONAL PESAWAT NIRAWAK LSU-05 (THE DESIGN OF THE LATERAL-DIRECTIONAL AUTOPILOT FOR THE LSU-05 UNMANNED AERIAL VEHICLE)
Authors: Fajar Muhammad , Arifianto Ony 
Published: March 2018

The autopilot on the aircraft is developed based on the mode of motion of the aircraft i.e. longitudinal and lateral-directional motion. In this paper, an autopilot is designed in lateral-directional mode for LSU-05 aircraft. The autopilot is designed at a range of aircraft operating speeds of 15 m/s, 20 m/s, 25 m/s, and 30 m/s at 1000 m altitude. Designed autopilots are Roll Attitude Hold, Heading Hold and Waypoint Following. Autopilot is designed based on linear model in the form of state-space. The controller used is a Proportional-Integral-Derivative (PID) controller. Simulation results show the value of overshoot / undershoot does not exceed 5% and settling time is less than 30 second if given step command. Abstrak Autopilot pada pesawat dikembangkan berdasarkan pada modus gerak pesawat yaitu modus gerak longitudinal dan lateral-directional. Pada makalah ini, dirancang autopilot pada modus gerak lateral-directional untuk pesawat LSU-05. Autopilot dirancang pada range kecepatan operasi pesawat yaitu 15 m/dtk, 20 m/dtk, 25 m/dtk, dan 30 m/dtk dengan ketinggian 1000 m. Autopilot yang dirancang adalah Roll Attitude Hold, Heading Hold dan Waypoint Following. Autopilot dirancang berdasarkan model linier dalam bentuk state-space. Pengendali yang digunakan adalah pengendali Proportional-Integral-Derivative (PID). Hasil simulasi menunjukan nilai overshoot/undershoot tidak melebihi 5% dan settling time kurang dari 30 detik jika diberikan perintah step.
As representações no ensino de química na perspectiva da semiótica peirceana
Authors: Wartha Edson José , Rezende Daisy de Brito 
Published: March 2018

Este artigo discute e apresenta possíveis potencialidades do uso de elementos da Semiótica Peirceana como instrumento para tratar do estatuto ontológico e epistemológico do papel das representações no Ensino de Química. Busca-se apresentar uma abordagem que leve em consideração o plano ontológico e o plano linguístico na discussão sobre a representação em Química e no Ensino de Química. Defende-se que na perspectiva da semiótica de Peirce é possível avançar nas discussões sobre o estatuto ontológico da representação.
QUÍMICA PARA DAMAS: los instructivos y elegantes diálogos de Jane Marcet (1806)
Authors: Trindade Lais Santos Pinto , Beltran Maria Helena Roxo 
Published: March 2018

Este estudio analiza el influyente papel de la mujer en la conservación, transmisión y difusión de los conocimientos sobre la materia, focalizando especialmente la obra Conversations on Chemistry (1806) de Jane Marcet. Aunque la participación de las mujeres en la manipulación y transformación de materiales es bastante antigua, este saber femenino sólo alcanzó vasta divulgación en el siglo XIX, en función del aumento de la alfabetización, desarrollo de la industria editorial y reevaluación de la educación femenina. En este escenario Jane Marcet, inspirada en las conferencias impartidas por Humphry Davy en la Royal Institution, escribió su libro dirigido especialmente a las mujeres, pues estaba convencida que los conocimientos químicos ampliarían su horizonte intelectual y las ayudaría a encontrar en la contemplación de la naturaleza una fuente de instrucción placentera.
Le sens en partage
Authors: Bisconti Valentina 
Published: March 2018

Peut-on identifier la signification comme objet spécifique d’un seul domaine d’études ?
Bien avant l’institution de la sémantique au XIXe siècle, la signification est analysée empiriquement par les lexicographes. S’agit-il d’une filiation ? La sémantique linguistique naît-elle de la lexicographie monolingue ?
Une dialectique, sans cesse réactivée dans le temps et à travers les différentes écoles, s’instaure entre sémanticiens et lexicographes en raison du partage conflictuel de cet objet commun qu’est le sens, ainsi que de toute une série de questions annexes : le statut du mot, l’articulation entre état de langue et histoire, la tension entre norme et usage, le choix entre polysémie ou homonymie, la place du locuteur dans le changement linguistique, etc.
Cette dialectique entre un savoir-faire empirique (lexicographie) et un savoir savant (sémantique) en matière de sens ne saurait s’expliquer par les conditions d’émergence et les incertitudes de méthode de la nouvelle discipline. Une méfiance tenace envers les dictionnaires est présente aussi bien chez les philologues du XIXe siècle que chez les linguistes, lexicologues et sémanticiens du XXe siècle travaillant dans des cadres théoriques aussi différents que le structuralisme, le générativisme et le cognitivisme.
L’ouvrage explique ainsi les transferts de méthode réciproques entre sémantique et lexicographie et montre à quel point la tension interdisciplinaire est une dynamique constitutive des savoirs sur le sens.
Oral Health Status and Treatment Needs of Inpatients at a Medical College Hospital in Haryana
Authors: Sogi Girish M , Veeresha Koratagere L 
Published: March 2018

ABSTRACT

Aim
To assess the oral health status and felt needs of patients admitted to medical/surgical wards.

Materials and methods
The cross-sectional study included 346 patients who were recruited from medical/surgical wards. Dental parameters were recorded using the World Health Organization (WHO) Oral Health Assessment Form for Adults, 2013.

Results
Mean age of patients was 40.77 [standard deviation (SD) ± 14.4] years; 36.4% aged > 45 years and 32.9% educated beyond 10 years of education. 77.2% used toothbrush and 75.7% toothpaste for cleaning of teeth. 91% brushed their teeth at least once a day and 77.7% performed tongue cleaning. Greater number of decayed teeth (3.43 ± 3.38) were seen in those educated ≤ 10 years when compared with those educated beyond this level (2.43 ± 2.55). Participants with low education attainment and higher age group (>45 years) had significantly more teeth missing due to caries/other reasons, and with deeper periodontal disease. Conversely, higher educated and younger aged group (<45 years) participants had significantly greater mean number of sound teeth and teeth without gingival and periodontal abnormalities. There was no significant difference between smokers and nonsmokers, those who ever visited a dentist or not, practicing or not practicing oral hygiene, using tobacco or not, those with diabetes mellitus and/or hypertension or without these conditions. Nearly 80% of the patients felt no requirement for dental treatment.

Conclusion
Despite adherence to oral hygiene practices, the oral health status of patients admitted to medical/surgical wards was poor.

How to cite this article
Avasthi A, Sogi GM, Veeresha KL. Oral Health Status and Treatment Needs of Inpatients at a Medical College Hospital in Haryana. J Postgrad Med Edu Res 2018;52(1):5-11.
A Bayesian modelling method for post-processing daily sub-seasonal to seasonal rainfall forecasts from global climate models and evaluation for 12 Australian catchments
Authors: Schepen Andrew , Zhao Tongtiegang , Wang Quan J. , Robertson David E. 
Published: March 2018

Abstract. Rainfall forecasts are an integral part of hydrological forecasting systems
at sub-seasonal to seasonal timescales. In seasonal forecasting, global
climate models (GCMs) are now the go-to source for rainfall forecasts.
For hydrological applications however, GCM forecasts are often biased and
unreliable in uncertainty spread, and calibration is therefore required
before use. There are sophisticated statistical techniques for calibrating
monthly and seasonal aggregations of the forecasts. However, calibration of
seasonal forecasts at the daily time step typically uses very simple
statistical methods or climate analogue methods. These methods generally lack
the sophistication to achieve unbiased, reliable and coherent forecasts of
daily amounts and seasonal accumulated totals. In this study, we propose and
evaluate a Rainfall Post-Processing method for Seasonal forecasts (RPP-S), which is
based on the Bayesian joint probability modelling approach for calibrating
daily forecasts and the Schaake Shuffle for connecting the daily ensemble
members of different lead times. We apply the method to post-process ACCESS-S
forecasts for 12 perennial and ephemeral catchments across Australia and for
12 initialisation dates. RPP-S significantly reduces bias in raw forecasts
and improves both skill and reliability. RPP-S forecasts are also more skilful and
reliable than forecasts derived from ACCESS-S forecasts that have been
post-processed using quantile mapping, especially for monthly and seasonal
accumulations. Several opportunities to improve the robustness and skill of
RPP-S are identified. The new RPP-S post-processed forecasts will be used in
ensemble sub-seasonal to seasonal streamflow applications.
Molecular Diagnostics in Pathology: Time for a Next-Generation Pathologist?
Authors: Fassan Matteo 
Published: March 2018

Context.—Comprehensive molecular investigations of mainstream carcinogenic processes have led to the use of effective molecular targeted agents in most cases of solid tumors in clinical settings.Objective.—To update readers regarding the evolving role of the pathologist in the therapeutic decision-making process and the introduction of next-generation technologies into pathology practice.Data Sources.—Current literature on the topic, primarily sourced from the PubMed (National Center for Biotechnology Information, Bethesda, Maryland) database, were reviewed.Conclusions.—Adequate evaluation of cytologic-based and tissue-based predictive diagnostic biomarkers largely depends on both proper pathologic characterization and customized processing of biospecimens. Moreover, increased requests for molecular testing have paralleled the recent, sharp decrease in tumor material to be analyzed—material that currently comprises cytology specimens or, at minimum, small biopsies in most cases of metastatic/advanced disease. Traditional diagnostic pathology has been completely revolutionized by the introduction of next-generation technologies, which provide multigene, targeted mutational profiling, even in the most complex of clinical cases. Combining traditional and molecular knowledge, pathologists integrate the morphological, clinical, and molecular dimensions of a disease, leading to a proper diagnosis and, therefore, the most-appropriate tailored therapy.
MIPhy: Identify and quantify rapidly evolving members of large gene families
Authors: Curran David M , Gilleard John S , Wasmuth James D 
Published: March 2018

After transitioning to a new environment, species often exhibit rapid phenotypic innovation. One of the fastest mechanisms for this is duplication followed by specialization of existing genes, which leaves a phylogenetic signature of lineage-specific expansions and contractions. These can be identified by analyzing the gene family across several species and identifying patterns of gene duplication and loss that do not correlate with the known relationships between those species. This signature, termed phylogenetic instability, has been previously linked to adaptations that change the way an organism samples and responds to its environment; conversely, low phylogenetic instability has been previously linked to proteins with endogenous functions.
Here, we present MIPhy, a method to identify and quantify phylogenetic instability by quantifying the incongruence of a gene’s evolutionary history. The motivation behind MIPhy was to produce a tool to aid in interpreting phylogenetic trees. It can predict which members of a gene family are under adaptive evolution, working only from a gene tree and the relationship between the species under consideration.
We demonstrate the usefulness of MIPhy by accurately predicting which members of the mammalian cytochrome P450 gene superfamily metabolize xenobiotics and which metabolize endogenous compounds. Our predictions correlate very well with known substrate specificities of the human enzymes. We also analyze the Caenorhabditis collagen gene family and use MIPhy to predict genes that produce an observable phenotype when knocked down in C. elegans, and show that our predictions correlate well with existing knowledge. The software can be downloaded and installed from https://github.com/dave-the-scientist/miphy under a BSD 2-clause license. It is also available as an online web tool at http://miphy.wasmuthlab.org.
Timetable Design for Minimizing Passenger Travel Time and Congestion for a Single Metro Line
Authors: Shen Yi , Ren Gang , Liu Yang 
Published: March 2018

This paper brings a proposal for a timetable optimization model for minimizing the passenger travel time and congestion for a single metro line under time-dependent demand. The model is an integer-programming model that systemically considers the passenger travel time, the capacity of trains, and the capacity of platforms. A multi-objective function and a recursive optimization method are presented to solve the optimization problem. Using the model we can obtain an efficient timetable with minimal passenger travel time and minimal number of congestion events on platforms. Moreover, by increasing the number of dispatches, the critical point from congestion state to free-flow state and the optimal timetable with minimal cost for avoiding congestion on platforms can be obtained. The effectiveness of the model is evaluated by a real example. A half-regular timetable with fixed headways in each operation period and an irregular timetable with unfixed headway are investigated for comparison.