bluuebunny/crossref_metadata_2025_split huggingface dataset:
Salesperson adoption and usage of mobile sales configuration tools
Authors: Sanakulov Nodir , Kalliomaa Sami , Karjaluoto Heikki 
Published: May 2018

PurposeThe purpose of this paper is to examine salespersons’ adoption and usage of mobile sales configuration tools (MSCT) and to identify areas for further development in this realm. Another objective is to offer a conceptualization of MSCT adoption.Design/methodology/approachFor this purpose, a qualitative case study approach was selected as the research method to better understand acceptance of a mobile configuration tool used by business-to-business (B2B) salespersons. Primary data were collected through semi-structured interviews, which included a series of open-ended questions to gain more detailed and contextual data.FindingsThe results obtained from the interviews indicated several important determinants of adoption of sales configuration tools, and three different personal innovativeness types were identified.Research limitations/implicationsThe current study has certain limitations that should be considered in future studies. First, the results of this study cannot be generalized in other contexts because of small number of participants (nine salespersons) included. Second, social desirability might have affected the results in a way that caused the salespersons to have been tempted to talk positively about MSCT.Practical implicationsBased on the findings several suggestions for managers and software developers are made such as further technical development of MSCT, development of common sales routine for all salespersons, mentoring new salespersons and establishing social media channels for salesperson to interact with each, share experience/knowledge.Originality/valueCurrent paper can serve as pathway toward understanding of MSCT adoption and usage as it opens new avenues as a source of hypotheses for a quantitative analysis of certain phenomena such as the correlation between MSCT usage and sales performance.
Examining the determinant factors of perceived online community usefulness using the expectancy value model
Authors: Hashim Kamarul Faizal , Tan Felix B. 
Published: May 2018

Purpose
This study aims to examine the determinant factors of perceived online community usefulness from a motivational point of view. The researchers have combined the use of the expectancy value model and the information system continuous-use model to predict continuous knowledge-sharing behaviour between online community members. This research provides an additional view of current literature focusing on technology-related factors.

Design/methodology/approach
This research has adopted a quantitative research method, with data being collected through a Web survey technique. The members of online business communities were invited to participate in the survey. A total of 220 respondents participated in the online survey. These data were then analysed using structural equation modelling.

Findings
The research findings revealed that motivation-related factors have a moderate ability to predict members’ perception of online community usefulness. The research findings have shown that attainment and utility values are two significant motivational factors, which can positively influence perceived online community usefulness. By promoting these values, continuous knowledge-sharing intentions can be encouraged through perceived online community usefulness.

Research limitations/implications
Having members from communities other than online business communities might deliver different results, given that they have different needs and values. Also, this study only received responses from active contributors within selected online business communities. The responses from non-active contributors were not included in this study.

Practical implications
This study provides practical suggestions on how the administrators and designers of an online community can promote positive values within their community platform, using motivation-related mechanisms.

Originality/value
The existing literature that examines the determinants of perceived online community usefulness have mainly directed attention towards technology-related factors. This study fills the gap by examining the determinant factors of this construct from a motivation perspective.
The amorphous nature of agile: no one size fits all
Authors: George Joey F. , Scheibe Kevin , Townsend Anthony M. , Mennecke Brian 
Published: May 2018

Purpose
This paper aims to investigate the extent to which newly agile organizations followed 2001’s Agile Manifesto, especially in terms of the 12 principles of the agile approach, as included in the Manifesto.

Design/methodology/approach
The authors conducted in-depth case studies of groups in three large business organizations that had recently adopted agile. Two researchers spent one day at each site, attending daily standups and conducting interviews with managers, developers and customers.

Findings
Across the three organizations, developers were faithful to two agile principles: the primacy of delivering valuable software continually and regular reflections on the process with an eye toward improvement. The developers were uniformly unfaithful to the principle that requires face-to-face communication. Each organization varied in their adherence to the remaining nine principles. Obstacles to faithful adoption included the experience of the organization with agile, the extent to which the industry was regulated and the extent to which developers and customers were physically dispersed.

Originality/value
While past research on agile development is extensive, this paper examines perspectives on the method and its adoption through the lens of the original Agile Manifesto and its 12 principles. The principles were grouped into three broader categories – software delivery, people and process – to provide additional insights and to sharpen the analysis.
How does humble leadership promote follower creativity? The roles of psychological capital and growth need strength
Authors: Wang Yanfei , Liu Jieqiong , Zhu Yu 
Published: May 2018

Purpose
The purpose of this paper is to develop a moderated mediation model to examine the roles that psychological capital (PsyCap) and growth need strength may play in the relationship between humble leader behaviors and follower creativity.

Design/methodology/approach
Data were collected from a three-wave survey study with a sample of 165 matched leader-follower questionnaires in China. Multiple regression analyses, moderated regression analysis and bootstrapping analysis were used to test the hypotheses.

Findings
The results show that humble leader behaviors positively influence follower creativity, PsyCap mediates this influence and growth need strength not only moderates the relationship between humble leader behaviors and PsyCap, but also amplifies the indirect relationship between humble leader behaviors and follower creativity via PsyCap.

Research limitations/implications
Common method bias may still exit, although the measures of research variables were gathered from different sources and with time separation. Additionally, this study is conducted in a single cultural context, which may raise the question about the generalizability of our findings to other cultural contexts.

Originality/value
The primary contribution is building and examining a conceptual model that focuses on the potential effect of humble leader behaviors on follower creativity. Additionally, by confirming the mediating role of PsyCap, the research further uncovers why followers under humble leader behaviors are more likely to engage in creativity, and the moderating role of growth need strength found in this study also offers additional insight into that followers may differ in the degree to which they are receptive to leader effect.
Using partial aggregation in spatial capture recapture
Authors: Milleret Cyril , Dupont Pierre , Brøseth Henrik , Kindberg Jonas , Royle J. Andrew , Bischof Richard 
Published: May 2018

Abstract

Spatial capture–recapture (SCR) models are commonly used for analysing data collected using noninvasive genetic sampling (NGS). Opportunistic NGS often leads to detections that do not occur at discrete detector locations. Therefore, spatial aggregation of individual detections into fixed detectors (e.g., centre of grid cells) is an option to increase computing speed of SCR analyses. However, it may reduce precision and accuracy of parameter estimations.

Using simulations, we explored the impact that spatial aggregation of detections has on a trade‐off between computing time and parameter precision and bias, under a range of biological conditions. We used three different observation models: the commonly used Poisson and Bernoulli models, as well as a novel way to partially aggregate detections (Partially Aggregated Binary model [PAB]) to reduce the loss of information after aggregating binary detections. The PAB model divides detectors into K subdetectors and models the frequency of subdetectors with more than one detection as a binomial response with a sample size of K. Finally, we demonstrate the consequences of aggregation and the use of the PAB model using NGS data from the monitoring of wolverine (Gulo gulo) in Norway.

Spatial aggregation of detections, while reducing computation time, does indeed incur costs in terms of reduced precision and accuracy, especially for the parameters of the detection function. SCR models estimated abundance with a low bias (<10%) even at high degree of aggregation, but only for the Poisson and PAB models. Overall, the cost of aggregation is mitigated when using the Poisson and PAB models. At the same level of aggregation, the PAB observation model out‐performs the Bernoulli model in terms of accuracy of estimates, while offering the benefits of a binary observation model (less assumptions about the underlying ecological process) over the count‐based model.

We recommend that detector spacing after aggregation does not exceed 1.5 times the scale‐parameter of the detection function in order to limit bias. We recommend the use of the PAB observation model when performing spatial aggregation of binary data as it can mitigate the cost of aggregation, compared to the Bernoulli model.
Oxidation resistance 1 is a novel senolytic target
Authors: Zhang Xin , Zhang Suping , Liu Xingui , Wang Yingying , Chang Jianhui , Zhang Xuan , Mackintosh Samuel G. , Tackett Alan J. , He Yonghan , Lv Dongwen , Laberge Remi‐Martin , Campisi Judith , Wang Jianrong , Zheng Guangrong , Zhou Daohong 
Published: May 2018

SummaryThe selective depletion of senescent cells (SCs) by small molecules, termed senolytic agents, is a promising therapeutic approach for treating age‐related diseases and chemotherapy‐ and radiotherapy‐induced side effects. Piperlongumine (PL) was recently identified as a novel senolytic agent. However, its mechanism of action and molecular targets in SCs was unknown and thus was investigated. Specifically, we used a PL‐based chemical probe to pull‐down PL‐binding proteins from live cells and then mass spectrometry‐based proteomic analysis to identify potential molecular targets of PL in SCs. One prominent target was oxidation resistance 1 (OXR1), an important antioxidant protein that regulates the expression of a variety of antioxidant enzymes. We found that OXR1 was upregulated in senescent human WI38 fibroblasts. PL bound to OXR1 directly and induced its degradation through the ubiquitin‐proteasome system in an SC‐specific manner. The knockdown of OXR1 expression by RNA interference significantly increased the production of reactive oxygen species in SCs in conjunction with the downregulation of antioxidant enzymes such as heme oxygenase 1, glutathione peroxidase 2, and catalase, but these effects were much less significant when OXR1 was knocked down in non‐SCs. More importantly, knocking down OXR1 selectively induced apoptosis in SCs and sensitized the cells to oxidative stress caused by hydrogen peroxide. These findings provide new insights into the mechanism by which SCs are highly resistant to oxidative stress and suggest that OXR1 is a novel senolytic target that can be further exploited for the development of new senolytic agents.
Randomized clinical trial to evaluate the effectiveness of enrofloxacin as a second‐line antibiotic for treatment of acute Escherichia coli mastitis
Authors: Shinozuka Yasunori , Kawai Kazuhiro , Takeda Akira , Yamada Michiaki , Kayasaki Fumi , Kondo Nao , Sasaki Yoshiko , Kanai Nahoko , Mukai Takuma , Sawaguchi Naoki , Higuchi Masaya , Kondo Haruka , Sugimoto Kouki , Yasuda Akane , Watanabe Aiko 
Published: May 2018

AbstractThe objective of the present study was to evaluate the effectiveness of enrofloxacin (ERFX) as a second‐line antibiotic for treatment of acute Escherichia coli (E. coli) mastitis. Forty‐two cows with naturally occurring acute E. coli mastitis were enrolled. On the first day of treatment (day 0), empirically selected antibiotics (oxytetracycline: n = 32, kanamycin: n = 10) were administered. Although systemic signs improved in 10 cows (first‐line group), the signs remained unchanged or worsened in 32 cows on day 1, including two cows that were found dead. The 30 surviving cows were randomly assigned to second‐line groups constituting an ERFX group (n = 19) or a control group (n = 11) that was treated with other antibiotics. Response to each treatment was evaluated by measuring clinical signs from day 0 to day 3, subsequent quarter milk recovery, and the 60‐day survival rate. Appetite on day 3 was significantly better in the ERFX group compared to the control group. No significant differences were observed in the 60‐day survival rate or the subsequent milk recovery between the ERFX group and the control group. Thus, the use of ERFX as a second‐line antibiotic for the treatment of acute E. coli mastitis could induce a rapid appetite recovery.
Effects of supplementary desalted mother liquor as replacement of commercial salt in diet for Thai native cattle on digestibility, energy and nitrogen balance, and rumen conditions
Authors: Sato Yoshiaki , Angthong Wanna , Butcha Patima , Takeda Motoharu , Oishi Kazato , Hirooka Hiroyuki , Kumagai Hajime 
Published: May 2018

AbstractFour Thai native cattle were used in a 4 × 4 Latin square design experiment to evaluate the availability of desalted mother liquor (DML) as replacement of salt in concentrate. Each cattle was assigned to one of the following concentrate feeding treatments: C1, 1% NaCl was added as salt; C2, 2% NaCl was added as salt; D1, 1% NaCl was replaced by DML; D2, 2% NaCl was replaced by DML, on a dry matter (DM) basis. The animals were fed rice straw and experimental concentrates (40:60) at 1.9% of body weight on a DM basis, daily. Acid detergent fiber expressed exclusive of residual ash (ADFom) digestibility in DML treatment was higher than salt treatment (p < .05) and D2 feeding showed the highest value (60.8%). There were no significant differences in blood metabolites, nitrogen retention, ruminal ammonia nitrogen, methane emission or energy efficiency among treatments. Molar percent of acetate on volatile fatty acids in rumen fluid 4 hr post‐feeding tended to be higher in DML treatment than salt treatment (p = .08). The results indicated that adding DML could improve ADFom digestibility and salt could be replaced by DML up to 2% as NaCl in concentrate without adverse effects on nitrogen balance, rumen conditions, blood metabolites and methane emission.
Hydroxycarbamide adherence and cumulative dose associated with hospital readmission in sickle cell disease: a 6‐year population‐based cohort study
Authors: Zhou Jifang , Han Jin , Nutescu Edith A. , Gordeuk Victor R. , Saraf Santosh L. , Calip Gregory S. 
Published: May 2018

AbstractSickle cell disease (SCD) is a congenital haemoglobinopathy that causes frequent acute care/emergency room visits and hospital admissions for affected individuals. Evidence from population‐based studies demonstrating the role of hydroxycarbamide (HC, also termed hydroxyurea) in reducing hospital readmission rates is limited. Our objective was to describe the use of HC and its association with acute care utilization and readmission rates using a large, nationally‐representative US health insurance claims database over a 6‐year period between 2009 and 2014. We identified 20 721 SCD‐related inpatient and acute care encounters. Patients had been exposed to HC within 6 months prior to admission in 4263 (21%) of SCD‐related admission events. HC use was more common among children aged 10–17 years and young adults aged 18–29 years. HC was associated with lower 30‐day all‐cause readmission rates in adults treated with average daily doses ≥1 g (odds ratio [OR], 0·72, 95% confidence interval [CI] 0·52–0·99) and doses of 0·5–1 g (OR, 0·73, 95% CI 0·57–0·93), compared to HC treatment with average daily doses of <0·5 g; adherence to HC with proportion of days covered of ≥0·80 was also associated with significantly lower 30‐day all‐cause readmission risks (OR, 0·59, 95% CI 0·41–0·84). Optimal therapeutic dosing and adherence to HC treatment significantly reduces 30‐day readmissions among patients with SCD.
Social communication in bats
Authors: Chaverri Gloriana , Ancillotto Leonardo , Russo Danilo 
Published: May 2018

ABSTRACTBats represent one of the most diverse mammalian orders, not only in terms of species numbers, but also in their ecology and life histories. Many species are known to use ephemeral and/or unpredictable resources that require substantial investment to find and defend, and also engage in social interactions, thus requiring significant levels of social coordination. To accomplish these tasks, bats must be able to communicate; there is now substantial evidence that demonstrates the complexity of bat communication and the varied ways in which bats solve some of the problems associated with their unique life histories. However, while the study of communication in bats is rapidly growing, it still lags behind other taxa. Here we provide a comprehensive overview of communication in bats, from the reasons why they communicate to the diversity and application of different signal modalities. The most widespread form of communication is the transmission of a signaller's characteristics, such as species identity, sex, individual identity, group membership, social status and body condition, and because many species of bats can rely little on vision due to their nocturnal lifestyles, it is assumed that sound and olfaction are particularly important signalling modes. For example, research suggests that secretions from specialized glands, often in combination with urine and saliva, are responsible for species recognition in several species. These olfactory signals may also convey information about sex and colony membership. Olfaction may be used in combination with sound, particularly in species that emit constant frequency (CF) echolocation calls, to recognize conspecifics from heterospecifics, yet their simple structure and high frequency do not allow much information of individual identity to be conveyed over long distances. By contrast, social calls may encode a larger number of cues of individual identity, and their lower frequencies increase their range of detection. Social calls are also known to deter predators, repel competitors from foraging patches, attract group mates to roost sites, coordinate foraging activities, and are used during courtship. In addition to sound, visual displays such as wing flapping or hovering may be used during courtship, and swarming around roost sites may serve as a visual cue of roost location. However, visual communication in bats still remains a poorly studied signal modality. Finally, the most common form of tactile communication known in bats is social grooming, which may be used to signal reproductive condition, but also to facilitate and strengthen cooperative interactions. Overall, this review demonstrates the rapid advances made in the study of bat social communication during recent years, and also identifies topics that require further study, particularly those that may allow us to understand adaptation to rapidly changing environmental conditions.
Immediate impact of a hurricane on the structure of a tropical butterfly community
Authors: Mullany Frances , Hollands Georgina , Snaddon Jake L. 
Published: May 2018

AbstractMore intense and frequent hurricanes may lead to long‐lasting effects to tropical ecosystems. Here, we describe the immediate impact on the butterfly community of a lowland forest in Belize, following Hurricane Earl. Species richness and abundance increased posthurricane, likely driven by convergence of the organization between the canopy and understory communities.
Injectable, compression‐resistant polymer/ceramic composite bone grafts promote lateral ridge augmentation without protective mesh in a canine model
Authors: Talley Anne D. , Boller Lauren A. , Kalpakci Kerem N. , Shimko Daniel A. , Cochran David L. , Guelcher Scott A. 
Published: May 2018

AbstractObjectiveThe objective of this study was to test the hypothesis that a compression‐resistant bone graft augmented with recombinant human morphogenetic protein‐2 (rhBMP‐2) will promote lateral ridge augmentation without the use of protective mesh in a canine model.Materials & MethodsCompression‐resistant (CR) bone grafts were evaluated in a canine model of lateral ridge augmentation. Bilateral, right trapezoidal prism‐shaped defects (13–14 mm long × 8–9 mm wide × 3–4 mm deep at the base) in 13 hounds (two defects per hound) were treated with one of four groups: (i) absorbable collagen sponge + 400 μg rhBMP‐2/ml (ACS, clinical control) protected by titanium mesh, (ii) CR without rhBMP‐2 (CR, negative control), (iii) CR + 200 μg rhBMP‐2 (CR‐L), or (iv) CR + 400 μg rhBMP‐2 (CR‐H). All animals were euthanized after 16 weeks. Ridge height and width and new bone formation were assessed by μCT, histology, and histomorphometry. The release kinetics of rhBMP‐2 from CR bone grafts in vitro and in vivo in a femoral condyle defect model in rabbits was also evaluated.ResultsAll four bone grafts promoted new bone formation (11–31.6 volume%) in the lateral ridge defects. For CR grafts, ridge height and width increased in a dose‐responsive manner with increasing rhBMP‐2 concentration. Ridge height and width measured for CR‐H without the use of protective mesh was comparable to that measured for ACS with a protective mesh.ConclusionsAt the same dose of rhBMP‐2, an injectable, compression‐resistant bone graft resulted in a comparable volume of new bone formation with the clinical control (ACS). These findings highlight the potential of compression‐resistant bone grafts without the use of protective mesh for lateral ridge augmentation.