bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of passive radio frequency identification technologies to monitor nest usage in the northern carmine bee‐eater (Merops n. nubicus)
Authors: Alba Andrew C. , Breeding Shawnlei , Valuska Annie J. , Sky Christy , Dunn Megan , Schutz Paul J. , Leighty Katherine A. , Ferrie Gina M. 
Published: September 2019

AbstractThe use of radio frequency identification (RFID) technology is common in animal‐monitoring applications in the wild and in zoological and agricultural settings. RFID is used to track animals and to collect information about movements and other behaviors, as well as to automate or improve husbandry. Disney's Animal Kingdom® uses passive RFID technology to monitor nest usage by a breeding colony of northern carmine bee‐eaters. We implemented RFID technologies in various equipment configurations, initially deploying low‐frequency (LF) 125 kHz RFID and later changing to high‐frequency (HF) 13.56 MHz RFID technology, to monitor breeding behavior in the flock. We installed antennas connected to RFID readers at the entrances of nest tunnels to detect RFID transponders attached to leg bands as birds entered and exited tunnels. Both LF‐RFID and HF‐RFID systems allowed the characterization of nest visitation, including the timing of nest activity, breeding pair formation, identification of egg‐laying females, participation by nonresidents, and detection of nest disruptions. However, we collected a substantially larger volume of data using the increased bandwidth and polling speed inherent with HF‐RFID, which permitted tag capture of multiple birds simultaneously and resulted in fewer missed nest visits in comparison to LF‐RFID. Herein, we describe the evolution of the RFID setups used to monitor nest usage for more than 7 years, the types of data that can be gained using RFID at nests, and how we used these data to gain insights into carmine bee‐eater breeding behavior and improve husbandry.
State Art, the Novel, and Architecture: Intersections
Authors: Billiani Francesca , Pennacchietti Laura 
Published: September 2019

AbstractBy identifying the relationships between a set of intersecting narratives about the novel and architecture, this chapter brings together the main lines of argument we have developed so far. More specifically, it analyses the intersections between State art, architecture and the novel, which emerge from the debates taking place in literary and cultural journals, such as Occidente, Orpheus and Il Saggiatore. These journals expressed the voice of the cultural fringes of the youth culture fostered by the regime during the period of its maximum consensus amongst the Italian population (1932–1936), in particular producing a timely reflection on realism, which functioned as a theoretical foundation for the discourse on State art and also for the creation of intersections between the novel and architecture.
Formaldehyde Adsorption–Desorption of Poplar Bark
Authors: Pásztory Zoltán , Halász Katalin , Börcsök Zoltán 
Published: September 2019

Abstract
This study investigated how the Populus × euramericana cv. Pannónia bark behaves in an environment containing formaldehyde. Prism shaped samples were formed from the bark and the prisms were kept in formaldehyde contaminated atmosphere for 1, 2, 5, 10, 18 and 36 days. After the contamination, the amount of the formaldehyde adsorbed and later the desorbed was measured. The formaldehyde content of the uncontaminated poplar bark was 0.0036 mg/g. The amount of bound formaldehyde showed a saturation curve as a function of time. The formaldehyde adsorption reached an equilibrium value of 0.9 mg HCHO/g bark. The emission of formaldehyde from contaminated bark samples showed an exponential curve as a function of time and some residual formaldehyde content was detected after the formaldehyde was released.
On existence and uniqueness of weak solutions for linear pantographic beam lattices models
Authors: Eremeyev Victor A. , Alzahrani Faris Saeed , Cazzani Antonio , dell’Isola Francesco , Hayat Tasawar , Turco Emilio , Konopińska-Zmysłowska Violetta 
Published: September 2019

AbstractIn this paper, we discuss well-posedness of the boundary-value problems arising in some “gradient-incomplete” strain-gradient elasticity models, which appear in the study of homogenized models for a large class of metamaterials whose microstructures can be regarded as beam lattices constrained with internal pivots. We use the attribute “gradient-incomplete” strain-gradient elasticity for a model in which the considered strain energy density depends on displacements and only on some specific partial derivatives among those constituting displacements first and second gradients. So, unlike to the models of strain-gradient elasticity considered up-to-now, the strain energy density which we consider here is in a sense degenerated, since it does not contain the full set of second derivatives of the displacement field. Such mathematical problem was motivated by a recently introduced new class of metamaterials (whose microstructure is constituted by the so-called pantographic beam lattices) and by woven fabrics. Indeed, as from the physical point of view such materials are strongly anisotropic, it is not surprising that the mathematical models to be introduced must reflect such property also by considering an expression for deformation energy involving only some among the higher partial derivatives of displacement fields. As a consequence, the differential operators considered here, in the framework of introduced models, are neither elliptic nor strong elliptic as, in general, they belong to the class so-called hypoelliptic operators. Following (Eremeyev et al. in J Elast 132:175–196, 2018.10.1007/s10659-017-9660-3) we present well-posedness results in the case of the boundary-value problems for small (linearized) spatial deformations of pantographic sheets, i.e., 2D continua, when deforming in 3D space. In order to prove the existence and uniqueness of weak solutions, we introduce a class of subsets of anisotropic Sobolev’s space defined as the energy space E relative to specifically assigned boundary conditions. As introduced by Sergey M. Nikolskii, an anisotropic Sobolev space consists of functions having different differential properties in different coordinate directions.
Surgical technique used in the UK for native tissue anterior pelvic organ prolapse repair (VaST)
Authors: Fairclough Emily , Segar Julia , Myers Jenny , Smith Anthony , Reid Fiona 
Published: September 2019

Abstract
Introduction
The PROSPECT study found that outcomes for native tissue and mesh prolapse repairs are similar but mesh repairs have a 10% risk of exposure. The current UK surgical mesh pause has led to renewed interest in native tissue surgery. Previous studies of native tissue anterior repair surgical techniques have been limited by the questionnaire study design. The objective of this study was to describe and categorise native tissue anterior repair surgical techniques.

Methods
This prospective qualitative study used a purposive sampling strategy to recruit surgeons. Data were collected through video-recorded observations of surgery, audio-recorded interviews with surgeons and field notes. The study took place in urogynaecology theatres in 21 UK centres. Thematic analysis was performed using computer-based software and themes of surgical technique were developed.

Results
Thirty consultant surgeons were recruited. In all steps of the anterior repair procedure, infiltration, dissection, method of fascial repair, type and method of suturing and suture placement, surgical technique varied between surgeons. The filming of surgery followed by immediate validation with the surgeons gave greater insight. Surgeons’ terminology to describe techniques varied and the investigators' opinions of the techniques performed were not always consistent with the surgeons' descriptions. The concept of fascia in histological terms was not uniform amongst surgeons.

Conclusion
VaST has demonstrated significant variation in native tissue anterior repair surgical techniques and inconsistency in the terminology used to describe them. These inconsistencies may prevent future meaningful research of prolapse surgery. The variation in technique could affect surgical outcomes and this should be explored further.
Critical assessment and integration of separate lines of evidence for risk assessment of chemical mixtures
Authors: Hernandez Antonio F. , Buha Aleksandra , Constantin Carolina , Wallace David R. , Sarigiannis Dimosthenis , Neagu Monica , Antonijevic Biljana , Hayes A. Wallace , Wilks Martin F. , Tsatsakis Aristidis 
Published: September 2019

AbstractHumans are exposed to multiple chemicals on a daily basis instead of to just a single chemical, yet the majority of existing toxicity data comes from single-chemical exposure. Multiple factors must be considered such as the route, concentration, duration, and the timing of exposure when determining toxicity to the organism. The need for adequate model systems (in vivo, in vitro, in silico and mathematical) is paramount for better understanding of chemical mixture toxicity. Currently, shortcomings plague each model system as investigators struggle to find the appropriate balance of rigor, reproducibility and appropriateness in mixture toxicity studies. Significant questions exist when comparing single-to mixture-chemical toxicity concerning additivity, synergism, potentiation, or antagonism. Dose/concentration relevance is a major consideration and should be subthreshold for better accuracy in toxicity assessment. Previous work was limited by the technology and methodology of the time, but recent advances have resulted in significant progress in the study of mixture toxicology. Novel technologies have added insight to data obtained from in vivo studies for predictive toxicity testing. These include new in vitro models: omics-related tools, organs-on-a-chip and 3D cell culture, and in silico methods. Taken together, all these modern methodologies improve the understanding of the multiple toxicity pathways associated with adverse outcomes (e.g., adverse outcome pathways), thus allowing investigators to better predict risks linked to exposure to chemical mixtures. As technology and knowledge advance, our ability to harness and integrate separate streams of evidence regarding outcomes associated with chemical mixture exposure improves. As many national and international organizations are currently stressing, studies on chemical mixture toxicity are of primary importance.
Appendectomy in Third Trimester of Pregnancy and Birth Outcomes: A Propensity Score Analysis of a 6‐Year Cohort Study Using Administrative Claims Data
Authors: Buitrago Giancarlo , Arevalo Kenndy , Moyano Juan Sebastian , Caycedo Ruben , Gaitan Hernando 
Published: September 2019

AbstractIntroductionWhile there is evidence of obstetric and neonatal outcomes from non‐obstetric surgery during pregnancy, surgery during the third trimester of gestation has not been evaluated as a prognostic factor for those outcomes. The objective of this study was to determine whether appendectomies during the third trimester are associated with adverse neonatal outcomes, in comparison with appendectomies during the first two trimesters, based on national administrative data in Colombia.MethodsA retrospective cohort study was performed using administrative health records. It included all women who had live births and who underwent an appendectomy during any stage of pregnancy, between the years 2011 and 2016, and who belonged to Colombia's contributory health system. The main outcome was preterm birth. Birth weight and 1‐min and 5‐min Apgar scores were also measured, as well as outcomes used to identify neonatal near‐miss cases. Propensity score matching was used in order to balance baseline characteristics (age, weeks of gestation, obstetric comorbidity index, and region and year the procedure was performed). Relative risks were estimated with Poisson regressions.ResultsThis study included a total of 2507 women in Colombia's contributory health system who underwent an appendectomy during pregnancy. Appendectomy was performed on 885 women (35.30%) in their first trimester, 1205 women (48.07%) in their second trimester, and 417 women (16.63%) in their third trimester. For the entire population, the preterm birth rate was 11.85 per 100 appendectomies. With the matched sample, this study found that women in their third trimester had a 1.65 greater risk of preterm birth [95% CI, 1.118–2.423], a 3.43 greater risk of birth at gestational ages < 33 weeks [95% CI, 1.363 to 8.625], 2.083 greater risk of weight under 1750 g [95% CI, 1.056–4.109], and a mean difference of − 0.247 [95% CI, − .382 to − .112] in the 1‐min Apgar score and − .168a [95% CI, − .276 to − .060] in the 5‐min Apgar. No differences were found in birth weight or Apgar scores < 7.ConclusionsIn Colombia's contributory health system, women who undergo appendectomies in their third trimester have a greater risk of preterm birth, birth weight under 1750 g, birth at gestational ages less than 33 weeks, and decreased 1‐min and 5‐min Apgar scores.
Impact of Polypharmacy and P-Glycoprotein- and CYP3A4-Modulating Drugs on Safety and Efficacy of Oral Anticoagulation Therapy in Patients with Atrial Fibrillation
Authors: Harskamp Ralf E. , Teichert Martina , Lucassen Wim A. M. , van Weert Henk C. P. M. , Lopes Renato D. 
Published: September 2019

Abstract

Purpose
To study whether polypharmacy or drug–drug interactions have differential effect on safety and efficacy in patients treated with direct oral anticoagulants (DOACs) versus warfarin.

Methods
We performed a systematic review and meta-analysis of studies that randomized patients with atrial fibrillation to DOACs or warfarin stratified by the number of concomitant drugs. Outcomes included stroke or systemic embolism (SE), all-cause mortality, major bleeding, and intracranial hemorrhage. Risk ratios (RR) were calculated and Mantel-Haenszel random effects were applied.

Results
Two high-quality studies were eligible, including 32,465 participants who received apixaban, rivaroxaban, or warfarin, with a median follow-up of 1.9 years. Of participants, 29% used < 5 drugs, 55% used 5–9 drugs, and 16% used ≥ 10 drugs. Drugs interacting with DOACs (P-glycoprotein/CYP3A4) were used by 6460 (20%) of patients. Patients with higher number of drugs (0–4 vs 5–9 vs ≥ 10) had higher rates of mortality (5.8%, 7.9%, 10.0%) and major bleeding (3.4%, 4.8%, 7.7%). Comparative efficacy or safety of DOACs versus warfarin was not affected by polypharmacy status or P-glycoprotein/CYP3A4 inhibitor use. However, the presence of polypharmacy (p = 0.001) or glycoprotein/CYP3A4-modulating drugs (p = 0.03) was correlated with increased risk of major bleeding when compared with warfarin. Overall, DOAC use was associated with a lower risk of stroke/SE (RR, 0.84; 95%CI, 0.74–0.94), all-cause mortality (RR, 0.91; 95%CI, 0.84–0.98), and intracranial hemorrhage (RR, 0.51; 95%CI, 0.38–0.70) compared with warfarin.

Conclusions
DOACs were more effective than warfarin, and at least as safe. Polypharmacy was associated with adverse outcomes and attenuated the advantage in risk of major bleeding among rivaroxaban users, particularly in the presence of P-glycoprotein/CYP3A4-modulating drugs.
Removal of organic pollutant (pyrene) from aqueous solution using coordination polymer of [Cu(Pic)2(H2O)2]·H2O (CP-1) as adsorbent
Authors: Tella Adedibu C. , Olawale Margaret D. , Obaleye Joshua A. , Adimula Vincent O. , Alimi Lukman O. , Ajibade Peter A. 
Published: September 2019

Abstract
Adsorptive removal of organic pollutant (pyrene) was carried out using coordination polymer [Cu(Pic)2(H2O)2]·H2O (CP-1) (where “Pic” represents picolinic acid), which was prepared from copper acetate monohydrate and picolinic acid. The compound was characterized by spectroscopic techniques, SEM, elemental and thermal analyses and X-ray crystallographic analysis. The crystal structure of CP-1 shows a centrosymmetric triclinic space group P-1 in which a = 5.0924 (4) Å, b = 7.5172 (6) Å, c = 9.0965 (8) Å. The Cu2+ ion is seen to have an octahedral geometry, which is bonded to oxygen atoms from the picolinic acid and nitrogen atoms from the pyridine rings. Pyrene adsorption from aqueous media was studied with the prepared adsorbent (CP-1). The kinetic model was observed to be second order, and the sorption data fitted best into the Langmuir model. The absorbent, CP-1, was shown to have a 90.91 mg/g adsorption capacity (maximum) for pyrene in this study at 25 °C. Compound CP-1 can thus be presented as a potential adsorbent in the treatment of pyrene-polluted water.
A rectal gastrointestinal stromal tumor—a plea for neoadjuvant imatinib and TAMIS
Authors: Balu Jagan , Subramanian Sankar , Suresh P , Shankar Narayanan AP , Sandhu Amamndeep Sing 
Published: September 2019

AbstractHere we describe an infrequent case of gastrointestinal stromal tumor of the rectum in a 57 year-old man with spindle cell neoplasm probably gastrointestinal stromal tumor and CT scan showed tumor from the anterior rectal wall and offered abdominoperineal resection for the same. The patient was started on imatinib and had a significant reduction in symptoms. The patient was reassessed with the CT scan, which showed a reduction in tumor size and Transanal minimally invasive surgery was planned for the patient. Use of imatinib prior to surgical resection to attain the reduced size of the tumor within the limit of resection is an attractive approach. Since tumor development can happen rapidly again after substantial tumor shrinkage, the best time to operate depending on resectability and the maximum therapeutic outcome remains divisive.
Big Data and Personalized Pricing
Authors: Steinberg Etye 
Published: September 2019

ABSTRACT:Technological advances introduce the possibility that, in the future, firms will be able to use big-data analysis to discover and offer consumers their individual reservation price (i.e., the highest price each consumer would be willing to pay, given their preferences and available income). This can generate some interesting benefits, such as a better state of affairs in terms of equality of both welfare and resources, as well as increased social welfare. However, these benefits are countered by considerations of relational equality. This article takes up the market-failures approach as its basis to demonstrate what is wrong with using big data to personalize prices. The article offers an improvement to the market-failures approach and argues that what is wrong with using big data to personalize prices is that it unfairly undermines consumers’ ability to benefit from the market, which is the very point of having a market.
Advancing regulatory science and assessment of FDA REMS programs: A mixed-methods evaluation examining physician survey response
Authors: Brewer Sarah E. , Campagna Elizabeth J. , Morrato Elaine H. 
Published: September 2019

AbstractPurpose:Food and Drug Administration’s (FDA) Draft Guidance for Industry on pharmaceutical REMS (Risk Evaluation and Mitigation Strategies) assessment and survey methodology highlights physician knowledge–attitudes–behaviors (KAB) surveys as regulatory science tools. This mixed-methods evaluation advances regulatory science and the assessment of FDA REMS programs when using physician surveys. We: (1) reviewed published physician survey response rates; and (2) assessed response bias in a simulation study of secondary survey data using different accrual cut-off strategies.Methods:A systematic literature review was conducted of US physician surveys (2000–2014) on pharmaceutical use (n = 75). Kruskal–Wallis tests were used to examine the relationships between response rates and survey design characteristics. The simulation was conducted using secondary data from a population-based physician KAB survey on diabetes risk management with antipsychotic use in Missouri Medicaid (n = 973 accrued over 30 weeks). Survey item responses were compared using Pearson’s chi-square tests for two faster completion simulations: Fixed Sample (n = 300) and Fixed Time (8 weeks).Results:Survey response rates ranged from 7% to 100% (median = 48%, IQR = 34%–68%). Surveys of targeted populations and surveys using member lists were associated with higher response rates (p = 0.02). In the simulation, 9 of 20 (45%) KAB items, including diabetes screening advocacy, differed significantly using the smaller Fixed Sample strategy (achieved in 12 days) versus full accrual. Fewer response differences were found using the Fixed Time strategy (2 of 20 [10%] items).Conclusions:Published data on physician surveys report low response rates with most associated with the sample source selected. FDA REMS assessments should include formal evaluation of survey accrual and response bias.
Types of iconicity and combinatorial strategies distinguish semantic categories in silent gesture across cultures
Authors: ORTEGA GERARDO , ÖZYÜREK ASLI 
Published: September 2019

abstractIn this study we explore whether different types of iconic gestures (i.e., acting, drawing, representing) and their combinations are used systematically to distinguish between different semantic categories in production and comprehension. In Study 1, we elicited silent gestures from Mexican and Dutch participants to represent concepts from three semantic categories: actions, manipulable objects, and non-manipulable objects. Both groups favoured the acting strategy to represent actions and manipulable objects; while non-manipulable objects were represented through the drawing strategy. Actions elicited primarily single gestures whereas objects elicited combinations of different types of iconic gestures as well as pointing. In Study 2, a different group of participants were shown gestures from Study 1 and were asked to guess their meaning. Single-gesture depictions for actions were more accurately guessed than for objects. Objects represented through two-gesture combinations (e.g., acting + drawing) were more accurately guessed than objects represented with a single gesture. We suggest iconicity is exploited to make direct links with a referent, but when it lends itself to ambiguity, individuals resort to combinatorial structures to clarify the intended referent. Iconicity and the need to communicate a clear signal shape the structure of silent gestures and this in turn supports comprehension.
Stress Drop, Apparent Stress, and Radiation Efficiency of Clustered Earthquakes in the Nucleation Volume of the 6 April 2009, Mw 6.1 L'Aquila Earthquake
Authors: Calderoni Giovanna , Rovelli Antonio , Di Giovambattista Rita 
Published: September 2019

AbstractWe investigate the variability of Brune stress drop (∆σ) and apparent stress (τa) of 23 earthquakes occurred in a small crustal volume adjacent to the hypocenter of the destructive Mw 6.1 L'Aquila earthquake. Their magnitude range is 2.7 ≤ Mw ≤ 4.1. Interevent variability of stress drop and apparent stress results in a factor of 10, well beyond the individual‐event uncertainty. Radiation efficiency ηsw = τa/∆σ varies mostly between 0.1 and 0.2, but in the days immediately before and after the main shock, ηsw tends to be smaller decreasing to values as low as 0.06. This may be the consequence of ruptures migrating in those days into a focal volume with higher dynamic strength. The temporal change of ηsw is tentatively interpreted as a spatial variation due to the earthquake migration into the locked portion of the fault that originated the main shock. Consistently, no variation in stress drop and apparent stress is observed between foreshocks and aftershocks but the smallest and largest ∆σ result in a good correlation with the largest and smallest b‐values, respectively, imaged by other authors in the rupture nucleation volume.