bluuebunny/crossref_metadata_2025_split huggingface dataset:
Positive interaction between work and home, and psychological availability on women’s work engagement: A “shortitudinal” study
Authors: Łaba Karolina , Geldenhuys Madelyn 
Published: August 2018

Orientation: Women’s work engagement is affected by how well they balance their work and personal life, and their level of confidence in their capability at work.Research purpose: Determine whether women’s daily psychological availability mediates daily positive work-home interaction and daily positive home-work interaction on daily work engagement.Motivation for the study: Research into negative work–home and home–work interaction is in abundance. Limited studies focus on the positive effects on women’s experiences at work (i.e. work engagement). Little is known about women’s psychological availability and how it affects their work. Furthermore, little research provides us insights into the day-level experiences of women at work.Research approach/design and method: A quantitative, shortitudinal design was used. Data analyses accounted for multilevel structure in the data (within-person vs. between-person differences). Female employees (n = 60) from various industries in Gauteng, completed electronic diaries in the form of a survey for 10 consecutive working days.Main findings: Daily psychological availability mediates between daily positive work-home interaction and daily work engagement. Daily positive home-work interaction did not predict daily work engagement, but had a significant effect on daily psychological availability.Practical/managerial implications: Examining systems and structures that promote opportunities for women to become more psychologically available at work impacts their sustainable retention.Contribution/value-add: This study found significant relationships between day-level uses of personal resources and spillover effects of home-work and work-home on day-level work engagement. The study further contributes to the literature on positive work–home and home–work interaction.
Creutzfeldt–Jakob disease with unusual presentation of peripheral neuropathy and ophthalmoplegia
Authors: Arwani Mais , Purohit Abhishek , Haddad Abdullah , Rana Sandeep 
Published: August 2018

AbstractCreutzfeldt–Jakob disease (CJD) is a well-described disease. It is characterized by rapidly progressive dementia, myoclonus, ataxia, pyramidal, and extrapyramidal signs. There are well-defined electroencephalogram and magnetic resonance imaging (MRI) findings, and markers found in the cerebrospinal fluid (CSF). The gold standard for diagnosing CJD remains brain biopsy. We present a case of a patient with a family history of biopsy-proven CJD who initially presented with symptoms of peripheral neuropathy. A month later, he developed ataxia, ophthalmoparesis, and then dysarthria. His initial workup was relatively unrevealing, showing an elevated protein in his CSF. He was thought to have Miller Fisher syndrome variant of Guillain–Barré syndrome. He neither, however, responded to plasmapheresis nor IVIG. He later started to develop progressive dementia. Repeated MRI showed restricted diffusion in the caudate and putamen, as well as in the cortex (cortical ribboning). Lumbar puncture was then found to be positive for 14-3-3 protein, total-tau protein, and real-time quaking-induced conversion assay, which are highly suggestive of CJD. We present a case of CJD with an unusual presentation resulting in misdiagnosis, prolonged workup, and potentially harmful treatment modalities. This case highlights the importance of broadening our definition of CJD to encompass more cases with unusual presentations.
Comparing climate change indices between a northern (arid) and a southern (humid) basin in Mexico during the last decades
Authors: Montero-Martínez Martín José , Santana-Sepúlveda Julio Sergio , Pérez-Ortiz Naydú Isabel , Pita-Díaz Óscar , Castillo-Liñan Salvador 
Published: August 2018

Abstract. It is a matter of current study to determine potential
climate changes in different parts of the world, especially in regions like
a basin which has the potential to affect socioeconomic and environmental
issues in a defined area. This study provides a comparison between several
climate change indices trends of two very different basins in Mexico, one
located in the northern arid region (the Conchos River basin) and the other
in the southern humid area (the Usumacinta River basin). First, quality
control, homogenization, and completion of the missing data were applied
before calculating the climate change indices and their respective trends
for the combined period 1961–1994. A clear warming signal was found for the
two basins in addition to an increment in the DTR, in agreement with other
studies in Mexico. Also, the Conchos River basin was found to be more humid
and the Usumacinta River basin drier, in accordance to a supposed seesaw
behavior indicated in previous analysis.
Comparative Utilization of Reverse and Anatomic Total Shoulder Arthroplasty: A Comprehensive Analysis of a High-volume Center
Authors: Chalmers Peter N. , Salazar Dane H. , Romeo Anthony A. , Keener Jay D. , Yamaguchi Ken , Chamberlain Aaron M. 
Published: August 2018

Introduction:
The purpose of this study was to determine how reverse and total shoulder arthroplasty (RTSA and TSA) comparative utilization, postoperative diagnoses, demographics, and perioperative data have changed between 2005 and 2015.

Methods:
This was a single-center retrospective review of all primary TSAs and RTSAs.

Results:
Our cohort included 1,192 RTSAs and 1,600 TSAs. Although both RTSA and TSA volume increased, RTSA increased from 27% to 52% of shoulder arthroplasty. The number of RTSAs performed for osteoarthritis and irreparable rotator cuff tears increased, and the proportion of RTSAs performed for rotator cuff tear arthropathy decreased. The mean age decreased for RTSA and TSA, and American Society of Anesthesiologists scores increased for both.

Discussion:
Over the past decade, RTSA has become the most common primary shoulder arthroplasty, reflecting the clinical success of the procedure. This increase is due to both an increase in the number of RTSAs performed for rotator cuff tear arthropathy as well as expanding surgical indications for RTSA.

Level of Evidence:
Retrospective, level IV
Treatment of upper urinary tract stones with flexible ureteroscopy in children
Authors: Xiao Jing , Wang Xiangyu , Li Jun , Wang Miaomiao , Han Tiandong , Zhang Caixiang , Du Yuan , Hao Gangyue , Tian Ye 
Published: August 2018

Introduction: This single-centre, retrospective study aimed to assess the efficacy and safety of flexible ureteroscopy (FURS) combined with holmium laser lithotripsy in treating children with upper urinary tract stones.
Methods: From June 2014 to October 2015, a total of 100 children (74 boys and 26 girls) with upper urinary tract stones were treated using FURS. A 4.7 Fr double-J stent was placed two weeks before operation. Patients were considered stone-free when the absence of residual fragments was observed on imaging studies. The preoperative, operative, and postoperative data of the patients were retrospectively analyzed.
Results: A total of 100 pediatric patients with a mean age of 3.51±1.82 years underwent 131 FURS and holmium laser lithotripsy. Mean stone diameter was 1.49±0.92 cm. Average operation time was 30.8 minutes (range 15–60). The laser power was controlled between 18 and 32 W, and the energy maintained between 0.6 and 0.8 J at any time; laser frequency was controlled between 30 and 40 Hz. Complications were observed in 69 (69.0 %) patients and classified according to the Clavien system. Postoperative hematuria (Clavien I) occurred in 64 (64.0 %) patients. Postoperative urinary tract infection with fever (Clavien II) was observed in 8/113 (7.1%) patients. No ureteral perforation and mucosa avulsion occurred. The overall stone-free rate of single operation was 89/100 (89%). Stone diameter and staghorn calculi were significantly associated with stone-free rate.
Conclusions: FURS and holmium laser lithotripsy is effective and safe in treating children with upper urinary tract stones.
A cross-sectional study of sexual function and fertility status in adults with congenital genitourinary abnormalities in a U.S. tertiary care centre
Authors: McCloskey Hannah , Kaviani Aaron , Pande Rashmi , Boone Timothy , Khavari Rose 
Published: August 2018

Introduction: We aimed to evaluate sexual function, sexual knowledge, and fertility status in adult patients with congenital genitourinary abnormalities (CGUA).
Methods: Adult patients with CGUA who were referred to a single transitional urology clinic between 2014 and 2017 were prospectively recruited to participate in the study. Questionnaires about general demographics, bowel and bladder continence, fertility, and sexuality were gathered. Validated questionnaires, including the Sexual Health Inventory for Men (SHIM) and Brief Index of Sexual Functioning for Women (BISF-W), were also collected.
Results: A total of 167 adults with CGUA were referred to our clinic within the defined time frame. Sixty patients (25 males, 35 females) with a mean age of 25.4 years (range 18–75) met inclusion criteria and responded to questionnaires pertaining to sexuality and fertility. Forty-five (75%) responded to the fertility questionnaire; 26 (58%) had never heard of assisted reproductive technologies, and only one had received prior fertility counselling. Fifty-eight participants (97%) responded to the sexuality questionnaire; 21 (36%) reported a history of sexual activity, with 12 (21%) being currently sexually active. Twenty (34%) wanted to learn more about sexuality and/or fertility. The SHIM response rate was 44%, and only three females (9%) completed the BISF-W in its entirety.
Conclusions: Adults with CGUA desire more sexuality and fertility education, yet they are uncomfortable completing current questionnaires. Our sexuality and fertility questionnaires are too challenging for this patient population to complete despite assistance. Thus, modifications are urgently needed. Additionally, medical providers should discuss sexual and reproductive health with these patients earlier and in more detail.
Restorative justice as empowerment: how to better serve the goals of punitive retribution
Authors: van Willigenburg Theo 
Published: August 2018

Restorative justice as empowerment: how to better serve the goals of punitive retribution
Restorative justice practices are applied only to the margins of criminal justice systems. These systems generally punish the wrongdoer in order to give him his ‘just desert’. For restorative justice to be more attractive, we need to understand why punitive retribution is such a powerful motive. If the scales of justice are out of balance because of suffering inflicted (to the offended), why would the infliction of more suffering (to the offender) bring redemption? It is argued that much of the sting of being harmed by an offender derives from the identity implications of the act. Punitive retribution may satisfy short-lasting vindictive desires, but its main symbolic function is to restore the victim’s self-image and dignity by humiliating the perpetrator. This is done in a notoriously indirect and ineffective way, though. It is argued that restorative justice can do much better, if it is understood in terms of empowering the offended. This involves procedures that restore the victim’s autonomy, prestige and self-confidence. Apart from bringing the offended back into the driver’s seat of the process, restorative justice empowers the survivors of crime by helping them face offenders, face themselves and face their community. Restorative justice is not only much more rewarding than punitive retribution, it also provides better ways of communicating personal and public disapproval of crime.
Validation of a Muscle-Specific Tissue Image Analysis Tool for Quantitative Assessment of Dystrophin Staining in Frozen Muscle Biopsies
Authors: Aeffner Famke , Faelan Crystal , Moore Steven A. , Moody Alexander , Black Joshua C. , Charleston Jay S. , Frank Diane E. , Dworzak Johannes , Piper J. Kris , Ranjitkar Manish , Wilson Kristin , Kanaly Suzanne , Rudmann Daniel G , Lange Holger , Young G. David , Milici Anthony J. 
Published: August 2018

Context.—Duchenne muscular dystrophy is a rare, progressive, and fatal neuromuscular disease caused by dystrophin protein loss. Common investigational treatment approaches aim at increasing dystrophin expression in diseased muscle. Some clinical trials include assessments of novel dystrophin production as a surrogate biomarker of efficacy, which may predict a clinical benefit from treatment.Objectives.—To establish an immunofluorescent scanning and digital image analysis workflow that provides an objective approach for staining intensity assessment of the immunofluorescence dystrophin labeling and determination of the percentage of biomarker-positive fibers in muscle cryosections.Design.—Optimal and repeatable digital image capture was achieved by a rigorously qualified fluorescent scanning process. After scanning qualification, the MuscleMap (Flagship Biosciences, Westminster, Colorado) algorithm was validated by comparing high-power microscopic field total and dystrophin-positive fiber counts obtained by trained pathologists to data derived by MuscleMap. Next, the algorithm was tested on whole-slide images of immunofluorescent-labeled muscle sections from Duchenne muscular dystrophy, Becker muscular dystrophy, and control patients.Results.—When used under the guidance of a trained pathologist, the digital image analysis tool met predefined validation criteria and demonstrated functional and statistical equivalence with manual assessment. This work is the first, to our knowledge, to qualify and validate immunofluorescent scanning and digital tissue image-analysis workflow, respectively, with the rigor required to support the clinical trial environments.Conclusions.—MuscleMap enables analysis of all fibers within an entire muscle biopsy section and provides data on a fiber-by-fiber basis. This will allow future clinical trials to objectively investigate myofibers' dystrophin expression at a greater level of consistency and detail.
Une cartographie des relations intermédiales entre le jeu vidéo et les autres médias dans le cadre des franchises transmédiatiques
Authors: Duret Christophe 
Published: August 2018

Cet article propose une cartographie sommaire de l’intermédialité telle qu’elle est mobilisée dans les recherches portant sur les relations entre le jeu vidéo et les autres médias au sein des franchises transmédiatiques. L’objectif poursuivi est d’identifier, grâce à une telle entreprise, plusieurs aspects problématiques du récit transmédiatique conceptualisé par Henry Jenkins : la complémentarité, la synergie et l’égalité statutaire des médias, la fluidité dans la circulation d’éléments fictionnels entre les textes et la cohérence narrative, par exemple. Afin de réduire l’angle mort intermédial que recèle le concept de récit transmédiatique, il convient de distinguer les phénomènes relevant de la transfictionnalité et de l’intermédialité (et plus précisément de l’intermédialité de milieu, de l’intermédialité formelle et de la référence intermédiale) qui s’y trouvent impliqués.
Comparison of gene expression profiles between human erythroid cells derived from fetal liver and adult peripheral blood
Authors: Tangprasittipap Amornrat , Kaewprommal Pavita , Sripichai Orapan , Sathirapongsasuti Nuankanya , Satirapod Chonthicha , Shaw Philip J. , Piriyapongsa Jittima , Hongeng Suradej 
Published: August 2018

BackgroundA key event in human development is the establishment of erythropoietic progenitors in the bone marrow, which is accompanied by a fetal-to-adult switch in hemoglobin expression. Understanding of this event could lead to medical application, notably treatment of sickle cell disease andβ-thalassemia. The changes in gene expression of erythropoietic progenitor cells as they migrate from the fetal liver and colonize the bone marrow are still rather poorly understood, as primary fetal liver (FL) tissues are difficult to obtain.MethodsWe obtained human FL tissue and adult peripheral blood (AB) samples from Thai subjects. Primary CD34+cells were culturedin vitroin a fetal bovine serum-based culture medium. After 8 days of culture, erythroid cell populations were isolated by flow cytometry. Gene expression in the FL- and AB-derived cells was studied by Affymetrix microarray and reverse-transcription quantitative PCR. The microarray data were combined with that from a previous study of human FL and AB erythroid development, and meta-analysis was performed on the combined dataset.ResultsFL erythroid cells showed enhanced proliferation and elevated fetal hemoglobin relative to AB cells. A total of 1,391 fetal up-regulated and 329 adult up-regulated genes were identified from microarray data generated in this study. Five hundred ninety-nine fetal up-regulated and 284 adult up-regulated genes with reproducible patterns between this and a previous study were identified by meta-analysis of the combined dataset, which constitute a core set of genes differentially expressed between FL and AB erythroid cells. In addition to these core genes, 826 and 48 novel genes were identified only from data generated in this study to be FL up- and AB up-regulated, respectively. Thein vivorelevance for some of these novel genes was demonstrated by pathway analysis, which showed novel genes functioning in pathways known to be important in proliferation and erythropoiesis, including the mitogen-activated protein kinase (MAPK) and the phosphatidyl inositol 3 kinase (PI3K)-Akt pathways.DiscussionThe genes with upregulated expression in FL cells, which include many novel genes identified from data generated in this study, suggest that cellular proliferation pathways are more active in the fetal stage. Erythroid progenitor cells may thus undergo a reprogramming during ontogenesis in which proliferation is modulated by changes in expression of key regulators, primarily MYC, and others including insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3), neuropilin and tolloid-like 2 (NETO2), branched chain amino acid transaminase 1 (BCAT1), tenascin XB (TNXB) and proto-oncogene, AP-1 transcription factor subunit (JUND). This reprogramming may thus be necessary for acquisition of the adult identity and switching of hemoglobin expression.
Occupational and Hobby Exposures Associated With Myositis Phenotypes in a National Myositis Patient Registry
Authors: Parks Christine G. , Wilkerson Jesse , Rose Kathryn M. , Faiq Abdullah , Farhadi Payam Noroozi , Bayat Nastaran , Schiffenbauer Adam , Brunner Hermine I. , Goldberg Bob , Sandler Dale P. , Miller Frederick W. , Rider Lisa G. 
Published: November 2024

ObjectiveThe objective of this study was to investigate occupational and hobby exposures to silica, solvents, and heavy metals and the odds of having the idiopathic inflammatory myopathy (IIM) phenotypes dermatomyositis (DM) and polymyositis (PM) versus inclusion body myositis (IBM), lung disease plus fever or arthritis (LD+), and systemic autoimmune rheumatic disease–associated overlap myositis (OM).MethodsThe sample included 1,390 patients (598 with DM, 409 with PM, and 383 with IBM) aged ≥18 years from a national registry. Of these, 218 (16%) were identified with LD+, and 166 (12%) with OM. Of these, 218 (16%) were identified with LD+, and 166 (12%) with OM. We calculated adjusted odds ratios (ORs) and 95% confidence intervals (CIs) and explored joint effects with smoking.ResultsHigh silica exposure was associated with increased odds of having DM (OR 2.02, 95% CI 1.18–3.46, compared to no exposure; P trend = 0.004), LD+ (OR 1.75, 95% CI 1.10–2.78, vs no LD; P trend = 0.005), and OM (OR 2.07, 95% CI 1.19–3.61, P trend = 0.020). Moderate to high heavy metals exposure was associated with greater odds of having LD+ (OR 1.49, 95% CI 1.00–2.14, P trend = 0.026) and OM (OR 1.59, 95% CI 0.99–2.55, P trend = 0.051). Greater odds of having LD+ were seen among smokers with moderate to high silica exposure versus nonsmokers with low or no exposure (high‐certainty assessment OR 2.53, 95% CI 1.31–4.90, P interaction = 0.061).ConclusionThese findings, based on a systematic exposure assessment, suggest that occupational and hobby exposures to silica and heavy metals contribute to adult IIM phenotypes, including DM, OM, and LD+, a possible marker for antisynthetase syndrome or other autoantibody‐associated lung diseases.
Exceeding 23% Efficiency for 3D/3D Bilayer Perovskite Heterojunction MAPbI3/FAPbI3‐Based Hybrid Perovskite Solar Cells with Enhanced Stability
Authors: Patil Jyoti V. , Mali Sawanta S. , Hong Chang Kook 
Published: November 2024

AbstractOrganic–inorganic hybrid perovskite solar cells (HPSCs) are gaining attention as a promising technology for next‐generation photovoltaic devices owing to their impressive power conversion efficiency (PCE) and cost‐effective fabrication methods. Although, solution‐processed passivation using 2D perovskites can improve the interface recombination, this approach hampers its effective charge transportation. In this study, the study investigates the properties and performance of the bilayer 3D/3D methylammonium lead iodide (MAPbI3)/formamidinium lead iodide (FAPbI3)‐based perovskite heterojunction (BPHJ) to address these concerns. The bilayer structure consists of two distinct perovskite absorbers having independent structure that are sandwiched between two charge transporting layer (CTLs) to make functional device. First, the fabrication process is optimized to achieve high‐quality MAPbI3 perovskite films with controlled morphology and crystallinity followed by the formation of BPHJ using FAPbI3 deposition by thermal evaporation technique. The BPHJ‐160 nm‐based PSCs with optimized parameters exhibit an enhanced PCE of 23.08% compared to single‐layer reference (20.15%) device. The improved performance can be attributed to the effective charge extraction at the heterojunction interface and reduced charge recombination losses due to favorable energy levels. Furthermore, the long‐term stability of the BPHJ‐based perovskite device is assessed under continuous illumination along with its ambient and thermal stability across different environmental conditions.
Delocalized Polarons in Diketopyrrolopyrrole‐Based Conjugated Polymers: Implications for Near‐Infrared Electrochromism and Beyond
Authors: Giri Dipanjan , Saha Shraman Kumar , Anderson Iona , Chakraborty Amit , Kala Jyotsana , Müller Jolanda Simone , Nelson Jenny , Canjeevaram Balasubramanyam Ram Kumar , Patil Satish 
Published: November 2024

AbstractConjugated polymers with delocalized polarons and near‐infrared (IR) absorption properties are promising materials for applications in electrochemical devices. However, the poor stability of low bandgap polymers in electrochemical redox conditions limits the realization of such devices. Herein, a new family of near‐IR absorbing conjugated polymers based on diketopyrrolopyrrole (DPP) derivatives with methoxy substituents to achieve reversible p‐type electrochemical doping with bistable near‐IR electrochromism is designed. The extent of volumetric doping in various electrolytes using cyclic voltammetry and spectroelectrochemistry for optimal electrochemical kinetics and near‐IR contrast is systematically investigated. Further, the spray‐coated films of polymers display high open circuit memory as the methoxylation is increased on the polymer backbone. The contrasting electrochromic memory and kinetics observed for these polymers are mainly ascribed to two factors; i) the effect of backbone structure on the spatial extent of polaron delocalization, and ii) the ionization energy of the polymers. The utility of DPP‐based polymers as energy‐efficient electrochromic optical attenuators (EVOAs) with high near‐IR coloration efficiencies, and an optical attenuation value of 5.1 dB at 1.3 and 1.5 µm wavelengths is demonstrated. Furthermore, the experimental findings are corroborated with theoretical studies to establish that the polaron delocalization length is central to the performance of the device.