bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modified Glanulopexy Technique for Supersonic Transporter Deformity and Glanular Hypermobility in Men With Penile Prostheses
Authors: Ziegelmann Matthew J. , Alom Manaf , Bole Raevti , Kohler Tobias , Trost Landon 
Published: May 2018

Abstract

Background
Glanular hypermobility (GH) or supersonic transporter (SST) deformity are occasionally encountered during penile prosthesis (PP) implantation, yet management strategies are underreported with minimal data available on surgical outcomes.

Aim
To describe a modified technique for glanulopexy to correct GH/SST in men undergoing PP placement and assess outcomes associated with this technique.

Methods
Glanulopexy was performed in men with GH/SST identified at the time of or following PP placement. A modification to previously described techniques was performed, whereby a suture is passed into the glans and secured to the tissue overlying the corpora through small incisions on the lateral aspects of the distal penile shaft.

Outcomes
Correction of the anatomic deformity (GH/SST), device infection, and changes in penile sensation were evaluated during post-operative follow-up.

Results
From 2014–2017, a total of 12 patients underwent modified glanulopexy for GH/SST. Nine (75%) were performed at the time of PP, while the remaining 3 were performed in a delayed fashion. At a median follow-up of 12 months (range 1–33 months), all patients with the device in situ demonstrated appropriate glanular positioning, and no patients reported changes in penile sensation. A single patient required device removal secondary to infection.

Clinical Translation
Glanulopexy with permanent suture successfully corrects severe GH or SST in men with inflatable PP without reduced penile sensation.

Conclusions
Strengths of the current study include the description of a simple, safe, and reproducible technique for GH/SST that adds minimal operative time and can be performed under local anesthesia when necessary. To our knowledge, this represents one of the largest reported series of glanulopexy outcomes reported in the literature. Limitations include that this is a single-surgeon series, there is limited follow-up, and lack of a comparison group. Further study with external validation is warranted to establish the optimal role for the procedure.
Geochemical evidence for the fractionation of iridium group elements at the early stages of crystallization of the Dovyren magmas (northern Baikal area, Russia)
Authors: Ariskin A.A. , Nikolaev G.S. , Danyushevsky L.V. , Fiorentini M. , Kislov E.V. , Pshenitsyn I.V. 
Published: May 2018

Abstract
We have first generalized geochemical and mineralogical data indicating the important role of crystallization of Os–Ir–Ru phases and fractionation of refractory iridium subgroup of PGE (IPGE) at the early stages of the evolution of parental magmas and primitive cumulates from the Yoko–Dovyren layered massif (northern Baikal area, Russia). The object of study was two types of plagioclase peridotites from the lower part of the intrusion, differing in the porosity of primary olivine cumulates: less melanocratic (but more primitive) type I and more melanocratic type II. Inclusions of refractory IPGE (Os, Ir, and Ru) discovered during LA–ICP-MS studies of aluminochromite from type I rocks are the first evidence for the presence of Os–Ir–Ru phases. Subsequent electron microscopy examinations revealed more than 25 grains of laurite and Ir-containing osmium in aluminochromite from plagioperidotites of both types. Attention is focused on the importance of the Ru/Cr2O3 and Ir/Cr2O3 ratios in rocks for the separation of IPGE at early and late fractionation stages. The conclusion is drawn that the higher Ru/Cr2O3 and Ir/Cr2O3 ratios in type I plagioperidotites indicate higher enrichment of aluminochromite in inclusions of refractory IPGE minerals. This is consistent with the fact that these rocks are assigned to the most primitive high-temperature ultramafites genetically related to the parental magma, which was in equilibrium with olivine Fo88 at ~1290 ºC. We have established that the parental Dovyren magma was already depleted in IPGE and rhodium before its entrance into a chamber. No signs of early sulfide–silicate immiscibility have been detected.
© 2018, V.S. Sobolev IGM, Siberian Branch of the RAS. Published by Elsevier B.V. All rights reserved.
Collisional mafic magmatism of the fold–thrust belts framing southern Siberia
(Western Sangilen, southeastern Tuva)
Authors: Shelepaev R.A. , Egorova V.V. , Izokh A.E. , Seltmann R. 
Published: May 2018

Abstract
We consider geochemical features of mafic magmatism manifested during the evolution of a complex nappe-folded structure in Western Sangilen, resulted from the Cambrian–Ordovician collisional tectogenesis. There are abundant ultramafic–mafic and mafic associations of different types in this region: layered low-Ti low-alkali ultramafic–mafic intrusions, high-Ti medium-alkali gabbroids, gabbro–monzodiorite intrusions, and alkali basalts. Isotope-geochronological data showed that these complexes formed over a wide time interval, from 570 to 440 Ma. At this time, the geodynamic setting in Western Sangilen changed from an island-arc one via a collision one to an intercontinental rift setting. At the early and late stages of the evolution of Western Sangilen, the geochemical features of mafites were typical of their geodynamic settings. The properties of mafites that formed synchronously with the collision are of particular interest. The studies have shown that the chemical composition of collisional mafites of Western Sangilen changed with time. They became richer in alkalies, titanium, and incompatible elements. This fact indicates a change in the type of mantle source from suprasubductional in the Cambrian to enriched deeper-level one in the Ordovician.
To MSNAP or not to MSNAP? Testing a small regional memory clinic against the UK Memory Service National Accreditation Program (MSNAP)
Authors: Sweeney E. B. , Foley J. E. , Fitzsimons S. , Denihan A. 
Published: May 2018

AimTo investigate whether a small regional memory clinic would benefit from engaging with a structured external audit process such as the Royal College of Psychiatrists’ Memory Service National Accreditation Program (MSNAP).BackgroundThe Psychiatry of Old Age service in Navan operates a public cognitive clinic. Despite the publication of the 2014 National Dementia Strategy, there are currently no national standards for memory clinics in Ireland. It may be beneficial to link in with an external quality control system as part of routine clinical governance.MethodsPublished data from the MSNAP group was reviewed and a set of audit materials extrapolated to replicate the MSNAP self-review process. The audit cycle involved (1) retrospective case review, (2) institution of a range of interventions and (3) a prospective audit, which included service user feedback.ResultsOverall the results demonstrated a high standard of service, especially in the areas of accessibility, assessment and communication of diagnosis. The clinic performed well against MSNAP key performance indicators. Patient and carer satisfaction with the service was very high. Clinic policies needed further development, particularly in the areas of referral, consent and data protection.ConclusionsThe process was useful, providing clear pointers for action. It highlighted the need to formalise organisational and practice policies, patient support and education, audit and outreach. Although accreditation is a laborious process requiring financial investment, it provides a strong scaffold to maintain and improve standards and is likely to be a valuable learning experience, where national guidelines are lacking.
A New Class of Maximal Triangular Algebras
Authors: Orr John Lindsay 
Published: May 2018

AbstractTriangular algebras, and maximal triangular algebras in particular, have been objects of interest for over 50 years. Rich families of examples have been studied in the context of many w*- and C*-algebras, but there remains a dearth of concrete examples in $B({\cal H})$. In previous work, we described a family of maximal triangular algebras of finite multiplicity. Here, we investigate a related family of maximal triangular algebras with infinite multiplicity, and unearth a new asymptotic structure exhibited by these algebras.
Labor and Dictatorship in Brazil: A Historiographical Review
Authors: Fontes Paulo , Corrêa Larissa R. 
Published: May 2018

AbstractThis article analyzes recent Brazilian scholarship on workers and trade unions during the military dictatorship (1964–1985), emphasizing the relative absence of studies and the neglect of worker organization. By focusing on working-class agency and the dilemmas the labor movement faced due to the regime's economic policies and fierce repression, this essay offers a better understanding of the political scenario after 1964. The second part of the article examines the themes of the most recent studies about workers and the labor movement during the military regime, emphasizing existing blind spots and future challenges for scholarship.
The Argentine Dictatorship and Labor (1976–1983): A Historiographical Essay
Authors: Basualdo Victoria 
Published: May 2018

AbstractThis article aims at briefly reviewing some of the main contributions on the transformations and role of the labor movement during the dictatorship in Argentina from 1976 to 1983. The analysis of the historiography will distinguish three main sub-periods: the 1980s, marked by the transition to democracy in Argentina; the 1990s, a decade during which neoliberal reforms were applied with full strength; and the post 2001-crisis, a time of economic growth and complex transformation of the academic sphere. It will examine approaches to two different complex and heterogeneous actors: the working class, its political and social role, as well as the labor force; and the trade-union movement, as the institutional organizations supposed to represent labor interests. In dialog with the historiographical analysis, the last part of the article will summarize some of the main existing open questions, as well as the possibly fruitful lines of research ahead.
Challenging Colonial Forced Labor? Resistance, Resilience, and Power in Senegal (1920s–1940s)
Authors: Tiquet Romain 
Published: May 2018

AbstractBased on the combination of colonial archives and the analysis of several complaints published in Senegalese newspapers, this article sheds light on the daily compulsory reality experienced by local populations with regards to forced labor in colonial Senegal (1920s–1940s). In contrast to analyses approaching forced labor systems through the study of colonial bureaucratic routines, this article studies the reactions of local populations and the consequences for colonial labor policies. I introduce the notion of resilience in order to overcome the pitfalls of the resistance paradigm and bring new insight into attitudes of distance, refusal, and adaptation used by local populations as methods to “absorb the shock” of everyday colonial coercion. More broadly, this analysis leads us to interrogate the limits and fragility of the colonial enterprise, recalling that the colonial state was not an almighty administration and that it was, above all, based on abiding adaptations and empirical decisions.
Fordist Absences: Madrid's Right to Housing Movement as Labor Struggle
Authors: Gonick Sophie 
Published: May 2018

AbstractThroughout the literature on contemporary populism in Europe, scholars point to increasing precarity brought about by post-Fordist labor relations as a central component in outrage on both the Left and the Right. Focusing on the case of Madrid and its right to housing movement, I instead argue that current mobilizations need to be understood as the product of the long absence of Fordist urban economic arrangements. I demonstrate how the working class was only able to attain full membership in the city during the recent economic boom. With the property crash, that membership appeared fleeting, triggering both inequality and outrage. Ultimately, I insist on the role of housing in the production of class formation and subjectivities.
Workers and the Right Wing: the Situation in India
Authors: Upadhyay Smriti 
Published: May 2018

AbstractWhy and how does a right-wing social movement mobilize workers along class lines? The Bharatiya Mazdoor Sangh (BMS), the labor wing of the Hindu nationalist movement in India, marshals working-class support by emphasizing workers’ class positions and identities. Following Gramsci, I argue that the BMS represents the Hindu right's recognition of workers’ class power and is thus key to the Hindu Right's efforts to incorporate workers into hegemonic capitalist social relations. The form that right-wing activity takes depends on the histories of working-class mobilization and the class power of workers. Thus, right-wing actors do not exclusively dictate the terms of the engagement with workers, but workers also exercise agency in shaping and contesting this interaction.
Individual and contextual risk factors for chikungunya virus infection: the SEROCHIK cross-sectional population-based study
Authors: Fred A. , Fianu A. , Béral M. , Guernier V. , Sissoko D. , Méchain M. , Michault A. , Boisson V. , Gaüzère B.-A. , Favier F. , Malvy D. , Gérardin P. ,   SEROCHIK group
Published: May 2018

AbstractThe purpose of the study was to weigh the community burden of chikungunya determinants on Reunion island. Risk factors were investigated within a subset of 2101 adult persons from a population-based cross-sectional serosurvey, using Poisson regression models for dichotomous outcomes. Design-based risk ratios and population attributable fractions (PAF) were generated distinguishing individual and contextual (i.e. that affect individuals collectively) determinants. The disease burden attributable to contextual determinants was twice that of individual determinants (overall PAF value 89.5% vs. 44.1%). In a model regrouping both categories of determinants, the independent risk factors were by decreasing PAF values: an interaction term between the reporting of a chikungunya history in the neighbourhood and individual house (PAF 45.9%), a maximal temperature of the month preceding the infection higher than 28.5 °C (PAF 25.7%), a socio-economically disadvantaged neighbourhood (PAF 19.0%), altitude of dwelling (PAF 13.1%), cumulated rainfalls of the month preceding the infection higher than 65 mm (PAF 12.6%), occupational inactivity (PAF 11.6%), poor knowledge on chikungunya transmission (PAF 7.3%) and obesity/overweight (PAF 5.2%). Taken together, these covariates and their underlying causative factors uncovered 80.8% of chikungunya at population level. Our findings lend support to a major role of contextual risk factors in chikungunya virus outbreaks.
Mining and petroleum boom and public spending policies in Niger: a dynamic computable general equilibrium analysis
Authors: Sangare Saadatou , Maisonnave Hélène 
Published: May 2018

AbstractThis study analyzes a public-spending option from mining and oil resources and its impact on Niger's economy. The windfall gain from mining and oil revenues provides an opportunity for the country to reinvest natural resource rents, enhance economic development, and address infrastructure gaps. Drawing on the country's recent and expected mining and oil exploitation, we evaluate the effects of a reinvestment policy in road infrastructure using a dynamic computable general equilibrium (CGE) model. We find that investment in road infrastructure brings positive spillover effects to other sectors of the economy and benefits to the economy in the long run. Our analysis additionally shows that reinvestment in road infrastructure, given the initial state of infrastructure in Niger, could help mitigate the resource curse.
The paradox of regulating negative emissions technologies under US environmental laws
Authors: Hester Tracy D. 
Published: May 2018

Non-technical summaryMost domestic environmental laws control the act of emitting pollutants into the environment. As a result, they do not apply squarely to negative emissions technologies (NETs) that remove ambient contaminants and do not emit pollutants themselves. As a result, current US environmental laws cannot readily govern a NET unless it has features that would typically allow regulation of a clean-up, such as ownership of the polluted resources, being at fault for polluting them or instituting projects to restore them. We should reinterpret such laws to focus on actual disruption or harm to the environment instead of using emission of pollutants as a proxy for ecological damage.
Actin like-6A promotes glioma progression through stabilization of transcriptional regulators YAP/TAZ
Authors: Ji Jianxiong , Xu Ran , Zhang Xin , Han Mingzhi , Xu Yangyang , Wei Yuzhen , Ding Kaikai , Wang Shuai , Bin Huang  , Chen Anjing , Di Zhang  , Jiang Zheng , Xu Shuo , Zhang Qing , Li Wenjie , Ni Shilei , Wang Jian , Li Xingang 
Published: May 2018

AbstractIncreased Actin-like 6A (ACTL6A) expression has been implicated in the development of diverse cancers and recently associated with the Hippo signaling pathway, which is known to regulate biological properties, including proliferation, tissue regeneration, stem cell biology, as well as tumorigenesis. Here we first show that ACTL6A is upregulated in human gliomas and its expression is associated with glioma patient survival. ACTL6A promotes malignant behaviors of glioma cells in vitro and in orthotopic xenograft model. In co-immunoprecipitation assays, we discover that ACTL6A physically associated with YAP/TAZ and furthermore disrupts the interaction between YAP and β-TrCP E3 ubiquitin ligase, which promotes YAP protein degradation. Moreover, effects of ACTL6A on glioma cells proliferation, migration, and invasion could be mediated by YAP/TAZ. These data indicate that ACTL6A may contribute to cancer progression by stabilizing YAP/TAZ and therefore provide a novel therapeutic target for the treatment of human gliomas.
Nodal-to-nodeless superconducting order parameter in LaFeAs1−xP
x
O synthesized under high pressure
Authors: Shiroka Toni , Barbero Nicolò , Khasanov Rustem , Zhigadlo Nikolai D. , Ott Hans Rudolf , Mesot Joel 
Published: May 2018

AbstractSimilar to chemical doping, pressure produces and stabilizes new phases of known materials, whose properties may differ greatly from those of their standard counterparts. Here, by considering a series of LaFeAs1−xP
x
O iron-pnictides synthesized under high-pressure high-temperature conditions, we investigate the simultaneous effects of pressure and isoelectronic doping in the 1111 family. Results of numerous macroscopic and microscopic technique measurements unambiguously show a radically different phase diagram for the pressure-grown materials, characterized by the lack of magnetic order and the persistence of superconductivity across the whole 0.3 ≤ x ≤ 0.7 doping range. This unexpected scenario is accompanied by a branching in the electronic properties across x = 0.5, involving both the normal and superconducting phases. Most notably, the superconducting order parameter evolves from nodal (for x < 0.5) to nodeless (for x ≥ 0.5), in clear contrast to other 1111 and 122 iron-based materials grown under ambient-pressure conditions.
Mitochondrial Complex I activity signals antioxidant response through ERK5
Authors: Khan Abrar Ul Haq , Allende-Vega Nerea , Gitenay Delphine , Garaude Johan , Vo Dang-Nghiem , Belkhala Sana , Gerbal-Chaloin Sabine , Gondeau Claire , Daujat-Chavanieu Martine , Delettre Cécile , Orecchioni Stefania , Talarico Giovanna , Bertolini Francesco , Anel Alberto , Cuezva José M. , Enriquez Jose A. , Cartron Guillaume , Lecellier Charles-Henri , Hernandez Javier , Villalba Martin 
Published: May 2018

AbstractOxidative phosphorylation (OXPHOS) generates ROS as a byproduct of mitochondrial complex I activity. ROS-detoxifying enzymes are made available through the activation of their antioxidant response elements (ARE) in their gene promoters. NRF2 binds to AREs and induces this anti-oxidant response. We show that cells from multiple origins performing OXPHOS induced NRF2 expression and its transcriptional activity. The NRF2 promoter contains MEF2 binding sites and the MAPK ERK5 induced MEF2-dependent NRF2 expression. Blocking OXPHOS in a mouse model decreased Erk5 and Nrf2 expression. Furthermore, fibroblasts derived from patients with mitochondrial disorders also showed low expression of ERK5 and NRF2 mRNAs. Notably, in cells lacking functional mitochondrial complex I activity OXPHOS did not induce ERK5 expression and failed to generate this anti-oxidant response. Complex I activity induces ERK5 expression through fumarate accumulation. Eukaryotic cells have evolved a genetic program to prevent oxidative stress directly linked to OXPHOS and not requiring ROS.
Detection of Chlamydiaceae and Chlamydia-like organisms on the ocular surface of children and adults from a trachoma-endemic region
Authors: Ghasemian Ehsan , Inic-Kanada Aleksandra , Collingro Astrid , Tagini Florian , Stein Elisabeth , Alchalabi Hadeel , Schuerer Nadine , Keše Darja , Babiker Balgesa Elkheir , Borel Nicole , Greub Gilbert , Barisani-Asenbauer Talin 
Published: May 2018

AbstractTrachoma, the leading infectious cause of blindness, is caused by Chlamydia trachomatis (Ct), a bacterium of the phylum Chlamydiae. Recent investigations revealed the existence of additional families within the phylum Chlamydiae, also termed Chlamydia-like organisms (CLOs). In this study, the frequency of Ct and CLOs was examined in the eyes of healthy Sudanese (control) participants and those with trachoma (case). We tested 96 children (54 cases and 42 controls) and 93 adults (51 cases and 42 controls) using broad-range Chlamydiae and Ct-specific (omcB) real-time PCR. Samples positive by broad-range Chlamydiae testing were subjected to DNA sequencing. Overall Chlamydiae prevalence was 36%. Sequences corresponded to unclassified and classified Chlamydiae. Ct infection rate was significantly higher in children (31.5%) compared to adults (0%) with trachoma (p < 0.0001). In general, 21.5% of adults and 4.2% of children tested positive for CLOs (p = 0.0003). Our findings are consistent with previous investigations describing the central role of Ct in trachoma among children. This is the first study examining human eyes for the presence of CLOs. We found an age-dependent distribution of CLO DNA in human eyes with significantly higher positivity in adults. Further studies are needed to understand the impact of CLOs in trachoma pathogenicity and/or protection.