bluuebunny/crossref_metadata_2025_split huggingface dataset:
Submillimeter Continuum Variability in Planck Galactic Cold Clumps
Authors: Park Geumsook , Kim Kee-Tae , Johnstone Doug , Kang Sung-ju , Liu Tie , Mairs Steve , Choi Minho , Lee Jeong-Eun , Sanhueza Patricio , Juvela Mika , Kang Miju , Eden David , Soam Archana , Montillaud Julien , Fuller Gary A. , Koch Patrick M. , Lee Chang Won , Stamatellos Dimitris , Rawlings Jonathan , Kim Gwanjeong , Zhang Chuan-Peng , Kwon Woojin , Yoo Hyunju 
Published: June 2019

Abstract
In the early stages of star formation, a protostar is deeply embedded in an optically thick envelope such that it is not directly observable. Variations in the protostellar accretion rate, however, will cause luminosity changes that are reprocessed by the surrounding envelope and are observable at submillimeter wavelengths. We searched for submillimeter flux variability toward 12 Planck Galactic Cold Clumps detected by the James Clerk Maxwell Telescope (JCMT)-SCUBA-2 Continuum Observations of Pre-protostellar Evolution (SCOPE) survey. These observations were conducted at 850

using the JCMT/SCUBA-2. Each field was observed three times over about 14 months between 2016 April and 2017 June. We applied a relative flux calibration and achieved a calibration uncertainty of ∼3.6% on average. We identified 136 clumps across 12 fields and detected four sources with flux variations of ∼30%. For three of these sources, the variations appear to be primarily due to large-scale contamination, leaving one plausible candidate. The flux change of the candidate may be associated with low- or intermediate-mass star formation assuming a distance of 1.5 kpc, although we cannot completely rule out the possibility that it is a random deviation. Further studies with dedicated monitoring would provide a better understanding of the detailed relationship between submillimeter flux and accretion rate variabilities while enhancing the search for variability in star-forming clumps farther away than the Gould Belt.
Graph Database Solution for Higher-order Spatial Statistics in the Era of Big Data
Authors: Sabiu Cristiano G. , Hoyle Ben , Kim Juhan , Li Xiao-Dong 
Published: June 2019

Abstract
We present an algorithm for the fast computation of the general N-point spatial correlation functions of any discrete point set embedded within an Euclidean space of

. Utilizing the concepts of kd-trees and graph databases, we describe how to count all possible N-tuples in binned configurations within a given length scale, e.g., all pairs of points or all triplets of points with side lengths < r
MAX. Through benchmarking, we show the computational advantage of our new graph-based algorithm over more traditional methods. We show measurements of the three-point correlation function up to scales of ∼200 Mpc (beyond the baryon acoustic oscillation scale in physical units) using current Sloan Digital Sky Survey (SDSS) data. Finally, we present a preliminary exploration of the small-scale four-point correlation function of 568,776 SDSS Constant (stellar) Mass (CMASS) galaxies in the northern Galactic cap over the redshift range of 0.43 < z < 0.7. We present the publicly available code GRAMSCI (GRAph Made Statistics for Cosmological Information; bitbucket.org/csabiu/gramsci), under a Gnu is Not Unix (GNU) General Public License.
Ruimtelijke mismatch, scholing en talenkennis in de Brusselse metropool: een analyse
Authors: Theys Tobias , Deschacht Nick , Adriaenssens Stef , Verhaest Dieter 
Published: June 2019

Ruimtelijke mismatch, waarbij werkzoekenden niet wonen waar jobs te vinden zijn, kan een belangrijke barrière zijn op de arbeidsmarkt, vooral voor kwetsbare groepen. In deze studie bekijken we de rol die ruimtelijke mismatch speelt in de Brusselse metropool. Met behulp van een verbeterde maatstaf, de distance-weighted spatial mismatch index, die locatie-gedreven mismatch mee in rekening brengt, vergelijken we de ruimtelijke mismatch tussen de hoog- en laaggeschoolde arbeidsmarkt en de arbeidsmarkt voor laaggeschoolden met en zonder talenkennis. In de meest ruime definitie van de Brusselse metropool, tonen de resultaten een ruimtelijke mismatch die 50 % groter is voor laaggeschoolden, in vergelijking met hooggeschoolden. Voor laaggeschoolden zonder talenkennis is de ruimtelijke mismatch 115 % groter dan voor laaggeschoolden met talenkennis. Dit verschil komt hoofdzakelijk voort uit een relatief teveel aan laaggeschoolde werkzoekenden (zonder talenkennis) in het Brussels-Hoofdstedelijk Gewest en een relatieve tekort in de eerste gordel gemeenten rond het Gewest.
Mauvais appariement spatial, niveau de scolarité et connaissances linguistiques dans la métropole bruxelloise : une analyse
Authors: Theys Tobias , Deschacht Nick , Adriaenssens Stef , Verhaest Dieter 
Published: June 2019

Le mauvais appariement spatial – les demandeurs d’emploi ne résident pas là où se trouvent les emplois – peut constituer une entrave importante sur le marché du travail, surtout pour les groupes vulnérables. Dans cette étude, nous examinons le rôle de cette inadéquation spatiale dans la métropole bruxelloise. À l’aide d’un indice de pondération amélioré, le distance-weighted spatial mismatch index, qui intègre l’inadéquation induite par la localisation, nous comparons le mauvais appariement spatial entre le marché de l’emploi hautement et faiblement qualifié et le marché de l’emploi faiblement qualifié avec et sans connaissances linguistiques. Au sens le plus large de la métropole bruxelloise, les résultats montrent un mauvais appariement spatial jusqu’à 50 % plus élevé pour les demandeurs d’emploi faiblement qualifiés par rapport aux hautement qualifiés. Pour les faiblement qualifiés sans connaissances linguistiques, il apparaît jusqu’à 115 % plus élevé par rapport aux faiblement qualifiés avec connaissances linguistiques. Cette différence découle principalement d’un excédent relatif de demandeurs d’emploi faiblement qualifiés (sans connaissances linguistiques) en Région de Bruxelles-Capitale et d’un déficit relatif dans les communes de la première ceinture autour de la Région.
Normalización de la estrategia de enseñanza-aprendizaje Giras de Campo, para planificación y ejecución de sus tres momentos de ejecución: el antes, durante y después
Authors: Villavicencio Navarro Juan José 
Published: June 2019

Las Giras de campo es una de las principales estrategias didáctica que relaciona la teoría aprendida en el salón de clases con la práctica del campo laboral; En este artículo se pone de manifiesto aspectos que juegan un papel relevante para la aplicación de dicha estrategia, cabe señalar que son pocas las evidencias documentadas que se tienen sobre las realizaciones de la misma; y en la actualidad para muchos estudiantes y profesores se ha convertido en una simple excursión más que un proceso de aprendizaje significativo, por esta y otras razones, en las instituciones de educación donde se pone en práctica esta importante estrategia se deben de contar con instrumentos, que vienen a ser formatos que evidencien y permitan una adecuada planificación de ejecución durante los tres grandes momentos de la gira de campo que son el antes, el durante y el después; estos momentos se necesitan, más aún en aquellas universidades que hacen uso de la carpeta docente, donde las evidencias del actuar de los docentes son un componente esencial de la misma, puesto que contribuye a tener una fuente de información sobre los alcances que esta estrategia puede tener en el aprendizaje de los estudiantes, y sin obviar la perspectiva que estos mismos tienen hacia las giras de campo en las que han sido participe, pero que en muchas veces no se les toma en cuenta su perspectiva, la cual es muy importante conocer para la mejora continua en la aplicación de las giras de campo.
Investment Analysis of Medium Scale Private Forest Plantation Development in Oyo State
Authors: Fasoro Oyinlola Abiodun 
Published: June 2019

Forest and non-forest products are becoming scarce in Nigeria due to insatiable want of the resources by the people. The performance of public sector forest plantation development in Nigeria has fallen short of expectation of various stakeholders, hence, the need for investment in Private Forest Plantation Development (PFPD), fostered towards increasing wood supply and reducing the pressure on natural forest. In this study, investment analysis of medium scale PFPD was investigated to show its feasibility. Measures such as Net Present Value (NPV), Benefit Cost Ratio (BCR), Internal Rate of Return (IRR), Annual Equivalent Value (AEV), Land Expected Value (LEV), Return on Investment (ROI) and Discounted Payback Period (DPBP) were used to analyse the cash flow statement of the investment.
The study showed that medium scale of Tectona grandis, Gmelina arborea, with few Terminalia spp. plantation of 20ha with 18 year rotation had NPV of ₦1,504,841.70, BCR of 1.35, IRR of 24.03%, AEV of ₦316,016.76ha-1, LEV of ₦2,186,997.89ha-1, ROI of 35% and DPBP of 17.7years. The results showed that the investment is feasible based on economic returns indices. It is recommended that PFPD should incorporate multiple land use systems and apply appropriate silvicultural techniques in order to maximize the net return.
Growth and Instability in Area, Production and Productivity of Barley in Haryana vis-à-vis India
Authors: Nimbrayan Parveen Kumar , Bhatia Sunita, Jitender Kumar , . Heena 
Published: June 2019

The present study has made an attempt to examine the instability in the area, production and productivity of barley crop in India and Haryana during three phases i.e. pre-green revolution, green revolution and post green revolution period. The study is based on secondary data and used three analytical methods. The results showed that in case of area, the instability is more in the post-green revolution than pre-green revolution period as the focus of the green revolution was mainly on other crops like rice and wheat. In case of production, instability showed a decreasing trend from pre- to post-green revolution period due to the adoption of new technology and good quality seeds during the green revolution. A same decreasing trend was observed in yield instability also. In case of growth pattern, the area in Haryana and India both shows a negative growth trend in the pre-green revolution. In case of production, in Haryana, negative growth trends were observed in the green revolution period but in the post-green revolution, it was positive growth; while in India as a whole growth rate was negative. In case of yield, the growth rate was positive in both Haryana and India.
Complementary Application of Inoculant in Post-emergence on Soybean Crop
Authors: Henrique Ivanildo Guilherme , `Pereira Cassiano Spaziani , Rosalino Amauri Júnior , Silva Vinícius Henrique Da , Veiga Bruno Conceição De , Silva Adriano Alves Da , Vieira Cristiane Ramos 
Published: June 2019

Objective: Inoculation is an important agricultural practice in soybean cultivation that guarantees high productivity without the external input of nitrogen. The objective of this study was to evaluate if the complementary of liquid inoculant (Bradyrhizobium japonicum), via leaf, in different times and different application rates, affects the nodulation, plant growth and soybean productivity.
Study design: A randomized complete block design (RCBD) was used, with four replications, in a 5x3 factorial scheme, evaluating the complementary inoculant application, via foliar (0; 75; 150; 225 e 300 mL ha-1), in three stages of vegetative development of the crop (V2, V4 e V6).
Location and duration of the study: The study was performed in a commercial area, in the municipality of Sinop, in the northern of Mato Grosso State, between October 2017 and February 2018.
Methodology: The cultivation was in soil classified as Red-yellow Latosol with of clayey texture, was in a direct seeding system, using the cultivar NS7901RR. The seeds used were treated and inoculated at sowing, with turfous inoculant and liquid. The experimental units received the complementary applications of inoculant, via pulverization, at 15, 21 and 28 days after emergence, according to the treatment.
Results: It was verify that the different times of application of foliar inoculant, does not condition significant differences to the parameters measured in this study. The complementary inoculant application affected, significantly, the leaf chlorophyll index (P <0.05), as well as the dry matter mass of the plants (P <0.001). Up to 300 mL ha-1, a gradual increase in grain yield was verified.
Conclusion: The complementary supply of liquid inoculant (B. japonicum), via foliar, in different rates application, affects the nodulation and development of the plants and the productive yield of the crop.
Impact of patient comfort on diagnostic image quality during PET/MR exam: A quantitative survey study for clinical workflow management
Authors: Chen Shuguang , Hu Pengcheng , Gu Yusen , Pang Lifang , Zhang Zheng , Zhang Yiqian , Meng Xiaolin , Cao Tuoyu , Liu Xin , Fan Zhijin , Shi Hongcheng 
Published: June 2019

AbstractBackgroundPET/MR is transferring from a powerful scientific research tool to an imaging modality in clinical routine practice. Whole body PET/MR screening usually takes 30–50 minutes to finish, during which a few factors might induce patient discomfort and further cause degraded image quality. The aim of this report is to investigate the patients' perception of the imaging procedure and its correlation with image quality.MethodsOne hundred and twenty patients (63 males and 57 females, average age = 51.3 years, range 22–70 years) who had been diagnosed with cancer or had previous history of cancer were recruited and scanned with a simultaneous PET/MR system. A questionnaire was given to all patients retrospectively after the PET/MR scan, which has nine questions to assess patients' feeling of the scan on a Likert scale scoring system (1–5, 1 as most satisfied). All PET/MR images were also visually examined by two experts independently to evaluate the quality of the images. Six body locations were assessed and each location was evaluated also with a Likert scale scoring system (1–5, 5 as the best quality). Mann–Whitney U­test was used for statistical analysis to check if there is significant correlation between image quality and patient perceptions.ResultsWith a total of 120 patients, 118 questionnaires were filled and returned for analysis. The patients’ characteristics were summarized in Table 4. The statistics of the patients’ perception in the questionnaire were illustrated in Tables 5–7. Statistical significant correlations were found between MR image quality and patients’ characteristics/perception.ConclusionOur results show that PET/MR scanning is generally safe and comfortable for most of the patients. Statistical analysis does not support the hypothesis that bad patient’s perception leads to degraded image quality.
Musculoskeletal Ultrasound Scanning Protocol Consensus Statements on Scanning Conventions and Documentation in the US
Authors: Torralba Karina D. , Choi Kristal S. , Salto Lorena M. , Fairchild Robert , Cannella Amy C. , Kissin Eugene Y. , Thiele Ralf , Evangelisto Amy , Nishio Midori J. ,   for the Ultrasound School of North American Rheumatologists
Published: June 2019

ObjectiveEuropean rheumatology and radiology‐determined standards have largely driven the execution of ultrasound in rheumatology (RhUS). How this translates to American rheumatologic practice has not been examined. A rheumatology‐driven consensus on documentation, scanning conventions, and tiered‐mastery designation for anatomic region views was developed in 2011 and served as the framework for training and clinical research validation. The present study was undertaken to update this consensus to reflect current utilization of musculoskeletal RhUS evaluation in the US.MethodsA 3‐round Delphi method study was conducted using a 96‐item questionnaire sent via Qualtrics survey software to 101 respondents experienced in RhUS education and scholarship. The target participant number was 38. High agreement was defined as ≥85% agreement on each item. McNemar's chi‐square test was used to analyze changes in agreement in the responses. Comments were reviewed for content analysis.ResultsA total of 46 respondents completed all 3 rounds. Of documentation and scanning convention statements, 80% and 100%, respectively, reached high agreement. Comments reflected the need for rheumatology‐defined and disease‐specific complete scan and limited scan definitions, separate from radiology‐defined definitions.ConclusionMany scanning conventions from 2011 remain relevant in current practice. There is a need to determine rheumatology‐defined descriptions for common procedural terminology codes for complete and limited scans that accurately reflect the current state of RhUS.
Topological Transformation‐Based Nanobarcoding for Detection and Enumeration of MicroRNAs and Single Nucleotide Polymorphism
Authors: Yuk Ji Soo , Shin Seung Won , Chun Sang Hun , Ku Bo Mi , Choi Yu Jeong , Lim Yong Taik , Luo Dan , Ahn Myung‐Ju , Um Soong Ho 
Published: June 2019

AbstractRNA biomarkers have been recently reported to be associated tightly with the diagnosis and prognosis of many diseases. Particularly, cancers considered to be a serious threat to primates are known to be vastly dominated by genetic networks where RNA plays a key role. RNAs are thus recognized as a major target group that can be used for numerous cancer treatments and it is still required to identify and enumerate them in an effective manner. Here, a new topological transformation‐based nanobarcoding technique (TNT) is first reported using fluorescence‐DNA barcodes engaged with graphene oxide (GOx) for effectively discriminating short RNAs such as miRNAs and their single nucleotide polyporphisms in tissue and plasma. Through topological transformation into 3D DNA–RNA polygonal structures, various kinds of microRNAs have been read at the same time and analyzed quantitatively. Also, it positively discerned epidermal growth factor receptor (EGFR) mutations known as single base variations of typical lung cancer specific RNAs. A single variant of 0.785% in target EGFR mutations is explicitly detected. It is speculated that the TNT may be a versatile method for polymerase chain reaction (PCR)‐free practical diagnosis of several clinical genetic deviations such as significant biotic RNA and genic fragments and would be a promising alternative to conventional PCR terrains.
Biospecific Monolayer Coating for Multivalent Capture of Circulating Tumor Cells with High Sensitivity
Authors: Chen Jie , Yu Leixiao , Li Yan , Cuellar‐Camacho Jose Luis , Chai Yamin , Li Dong , Li Yueguo , Liu Hongyu , Ou Lailiang , Li Wenzhong , Haag Rainer 
Published: June 2019

AbstractThe isolation and detection of rare circulating tumor cells (CTCs) from patient peripheral blood can help to monitor the metastatic spread of carcinoma and evaluate therapeutic outcomes. However, it is technically challenging to isolate CTCs due to extreme rarity in blood. Current techniques typically have to utilize complex instrumentation to capture CTCs, resulting in nonapplicability. Inspired from the mussel adhesion, a polyglycerol‐based block polymer is used to fabricate a biospecific and bioinert interface for isolating CTCs with high selectivity and efficiency. Benefitting from the antifouling polyglycerol, the resulting monolayer coating greatly suppresses the nonspecific cells adhesion. Compared with one anti‐epithelial cell adhesion molecule (anti‐EpCAM), the CTCs' capture efficiency was improved to 95% when multiple receptors, i.e. anti‐EpCAM/Human epithelial receptor 2 (Her2)/Epithelial Growth Factor receptor (EGFR) are employed, even for low EpCAM‐expressing CTCs. The CTCs detection limit on the presented surface is as low as 1 cell mL−1. Furthermore, CTCs are isolated from breast cancer patients' blood sample with a high selectivity. Also, the CTCs can be released and still keep proliferation capability for downstream analysis. This multifunctional block polymer surface coating is quite cost effective and highly applicable for CTCs' isolation in the clinic, which can provide a new prospect for designing the next‐generation of bio/nanointerfaces for biomedical studies.
Immunogold FIB‐SEM: Combining Volumetric Ultrastructure Visualization with 3D Biomolecular Analysis to Dissect Cell–Environment Interactions
Authors: Gopal Sahana , Chiappini Ciro , Armstrong James P. K. , Chen Qu , Serio Andrea , Hsu Chia‐Chen , Meinert Christoph , Klein Travis J. , Hutmacher Dietmar W. , Rothery Stephen , Stevens Molly M. 
Published: June 2019

AbstractVolumetric imaging techniques capable of correlating structural and functional information with nanoscale resolution are necessary to broaden the insight into cellular processes within complex biological systems. The recent emergence of focused ion beam scanning electron microscopy (FIB‐SEM) has provided unparalleled insight through the volumetric investigation of ultrastructure; however, it does not provide biomolecular information at equivalent resolution. Here, immunogold FIB‐SEM, which combines antigen labeling with in situ FIB‐SEM imaging, is developed in order to spatially map ultrastructural and biomolecular information simultaneously. This method is applied to investigate two different cell–material systems: the localization of histone epigenetic modifications in neural stem cells cultured on microstructured substrates and the distribution of nuclear pore complexes in myoblasts differentiated on a soft hydrogel surface. Immunogold FIB‐SEM offers the potential for broad applicability to correlate structure and function with nanoscale resolution when addressing questions across cell biology, biomaterials, and regenerative medicine.
The Future of Neuroimplantable Devices: A Materials Science and Regulatory Perspective
Authors: Obidin Nikita , Tasnim Farita , Dagdeviren Canan 
Published: June 2019

AbstractThe past two decades have seen unprecedented progress in the development of novel materials, form factors, and functionalities in neuroimplantable technologies, including electrocorticography (ECoG) systems, multielectrode arrays (MEAs), Stentrode, and deep brain probes. The key considerations for the development of such devices intended for acute implantation and chronic use, from the perspective of biocompatible hybrid materials incorporation, conformable device design, implantation procedures, and mechanical and biological risk factors, are highlighted. These topics are connected with the role that the U.S. Food and Drug Administration (FDA) plays in its regulation of neuroimplantable technologies based on the above parameters. Existing neuroimplantable devices and efforts to improve their materials and implantation protocols are first discussed in detail. The effects of device implantation with regards to biocompatibility and brain heterogeneity are then explored. Topics examined include brain‐specific risk factors, such as bacterial infection, tissue scarring, inflammation, and vasculature damage, as well as efforts to manage these dangers through emerging hybrid, bioelectronic device architectures. The current challenges of gaining clinical approval by the FDA—in particular, with regards to biological, mechanical, and materials risk factors—are summarized. The available regulatory pathways to accelerate next‐generation neuroimplantable devices to market are then discussed.