bluuebunny/crossref_metadata_2025_split huggingface dataset:
APA KABAR PEMBAHARUAN PEMIKIRAN ISLAM? (Meneropong Pembaharuan Pemikiran Islam Post Cak Nur - Gus Dur)
Authors: Iqbal Moch 
Published: September 2019

In the 1990s the world of Islamic thought was very crowded and dynamic. There are some Islamic thinkers of the country who are very interested in producing discourses on Islamic thought. Some of them were (alm) Nurcholis Madjid and (alm) Abdurrahman Wahid (Gus Dur). Although the political realm of the homeland at that time began to warm up, the Islamic thought movement was very dynamic. After the fall of the new Order in 1998, and the death of several Islamic thinkers, the Islamic thought movement seemed to experience congestion. Even now it is quiet from healthy Islamic thinking. All components of thought are absorbed in the ups and downs of the political stage which attracts much attention. the results of this paper show that the political stage turned out to be more attractive to the generation of Islamic intellectuals post Cak Nur - Gus Dur.
Fenomena Dose Dependent Manner Efek Jahe Gajah terhadap Cedera Jaringan Hati pada Sindrom Metabolik
Authors: Nasution Agista Rohani Yasmin , Noormartany Noormartany , Yulianti Arief Budi , Indriyanti Raden Anita , Tejasari Maya 
Published: September 2019

Sindrom Metabolik merupakan kelainan metabolik kompleks yang memiliki komponen utama obesitas, resistensi insulin, dislipidemia, dan hipertensi. Penyakit ini dapat berlanjut menjadi penyakit perlemakan hati non-alkoholik yang ditandai dengan adanya cedera jaringan hati. Parameter yang dapat menandakan cedera jaringan hati adalah peningkatan kadar AST dan ALT. Peningkatan stres oksidatif mendasari terjadinya penyakit ini, sehingga untuk mengatasinya dapat menggunakan antioksidan, salah satunya adalah jahe. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian fraksi etil asetat jahe gajah terhadap kadar AST dan ALT pada mencit sindrom metabolik. Penelitian ini merupakan penelitian eksperimental in vivo menggunakan mencit galur Swiss Webster yang terbagi dalam empat kelompok, yaitu kelompok kontrol yang tidak diberikan perlakuan dan tiga kelompok perlakuan yang diberi fraksi etil asetat jahe gajah dengan konsentrasi 0,78mg/kgBB/hari, 1,56mg/kgBB/hari, 3,12/kgBB/hari. Hasil penelitian menunjukkan kelompok perlakuan 1 memiliki kadar AST dan ALT lebih rendah dibandingkan kelompok kontrol sedangkan kelompok perlakuan 2 dan 3 lebih tinggi dibandingkan kelompok kontrol. Hal ini menunjukan bahwa pada kelompok perlakuan satu, fraksi jahe dapat mencegah cedera jaringan hati sedangkan pada kelompok perlakuan dua dan tiga justru merusak jaringan hati. Dapat disimpulkan fraksi etil asetat jahe gajah memengaruhi cedera jaringan hati pada mencit model sindrom metabolik secara dose dependent manner.
Pemberian Ekstrak Curcuma Longa L. Meningkatkan Proliferasi Sel MEF yang dilakukan Scratch Test
Authors: Berbudi Afiat , Ifham Hanif Muhammad , Cintami Putri Almahitta 
Published: September 2019

Abstract: Proliferation Enhancement of Curcuma Longa L. Extract Treatment in MEF Cell Cultres that Treated by Scratch Test. Wound prevalence is still high and becomes a problem of healing process. Improper wounds management can cause wound healing disturbance, so that the healing process will be longer. For this reason, alternative medicine is required to shorten healing process and reduce medical costs. This study aims to determine the eﬀect of Curcuma longa L. extract on enhancement of mouse embryonic fibroblast cell proliferation carried out in vitro scratch test with the research method using a laboratory in vitro experimental design and 24 hour observation. Observations were carried out for 24 hours with variations in Curcuma longa L. extract concentration 2.5 ppm, 5 ppm, 10 ppm, 25 ppm and 50 ppm. The results showed that Curcuma longa L extract was able to accelerate the proliferation of mouse embryonic fbroblast cells which scratch test. After 24 hours, the highest gap closure were observed in mouse embryonic fbroblast cell culture using dose of 2.5 ppm of Curcuma longa L. extract administration. At a dose of ≥10 ppm it does not show proliferation in embryonic fbroblast mouse cells but causes toxicity to cells. Abstrak: Pemberian Ekstrak Curcuma Longa L. Meningkatkan Proliferasi Sel MEF yang dilakukan Scratch Test. Prevalensi luka yang tinggi masih menjadi permasalahan tersendiri dalam proses penyembuhan. Penanganan luka yang tidak tepat dapat menyebabkan gangguan penyembuhan sehingga proses penyembuhan menjadi panjang. Untuk itu perlu alternatif pengobatan yang dapat mempersingkat penyembuhan dengan biaya pengobatan yang lebih murah. Penetian ini bertujuan mengetahui pengaruh pemberian ekstrak Curcuma longa L. terhadap peningkatan proliferasi sel mouse embryonic fibroblast yang dilakukan scratch test secara in vitro dengan metode penelitian menggunakan desain eksperimen in vitro laboratoris dan dilakukan pengamatan selama 24 jam. Variasi konsentrasi ekstrak Curcuma longa L menggunakan dosis 2.5 ppm, 5 ppm, 10 ppm, 25 ppm dan 50 ppm. Hasil pengamatan menunjukkan bahwa ekstrak Curcuma longa L. mampu mempercepat proliferasi sel mouse embryonic fbroblast yang dilakukan scratch test dengan dosis optimum 2.5 ppm. Pada dosis ≥10 ppm tidak menunjukkan proliferasi pada sel mouse embryonic fbroblast tetapi menyebabkan toksisitas pada sel.
Perancangan Model Sistem Informasi Tuberkulosis Paru Terintegrasi Berbasis Web
Authors: Sunaryo Putra Gandha , Hariana Evy 
Published: September 2019

Abstract: Design of Web-Based Integrated Pulmonary Tuberculosis Information Model. Pulmonary TB is one of the health problems in Sintang District where in 2016 Pulmonary TB Case Notifcation Rate (CNR) is 100/100,000 population. An important step that must be carried out by the Sintang District Health Office is to evaluate the Pulmonary TB program. Based on preliminary studies, the evaluation of the Pulmonary TB control program is still not working properly. This is because the data management process is still done manually so that reports are often late. Therefore, the need for an appropriate information system model and in accordance with the needs of TB program users to support the evaluation of the Pulmonary TB program. The purpose of this study was to design a web-based integrated pulmonary TB information system model to support the evaluation of Pulmonary TB programs. This research is a qualitative research. Subjects in this study were all users of the TB information system consisting of Head of Division, Section Head, TB Wasor, TB Staﬀ in Health Service and several managers of Pulmonary TB programs. The results of this study were obtained a design model of integrated WEB-based TB information system based on the needs and desires of system users. Sintang District Health Office is recommended to build a system that has been designed based on the needs of system users so that the problem of the TB information system can be overcome. Abstrak: Perancangan Model Sistem Informasi Tuberkulosis Paru Terintegrasi Berbasis Web. TB Paru merupakan salah satu permasalahan kesehatan di Kabupaten Sintang yang pada tahun 2016 memiliki Case Notifcation Rate (CNR) sebesar 100/100.000 penduduk. Langkah penting yang harus dilakukan oleh Dinas Kesehatan Kabupaten Sintang adalah melakukan evaluasi program TB Paru. Kegiatan evaluasi program penanggulangan TB Paru masih belum berjalan sebagaimana mestinya. Hal ini disebabkan proses pengelolaan data masih dilakukan secara manual sehingga laporan sering terlambat. Oleh karena itu, perlu dikembangkan suatu model Sistem Informasi yang tepat serta sesuai dengan kebutuhan pengguna program TB guna mendukung evaluasi program TB Paru. Tujuan penelitian ini adalah untuk merancang model Sistem Informasi Tuberkulosis Paru terintegrasi berbasis Web untuk mendukung evaluasi program TB Paru. Penelitian ini merupakan penelitian kualitatif. Subjek dalam penelitian ini adalah semua pengguna Sistem Informasi TB yang terdiri dari Kepala Bidang, Kepala Seksi, Wasor TB, Staf TB Dinas Kesehatan dan beberapa pengelola program TB Paru. Penelitian ini menghasilkan suatu model rancangan Sistem Informasi TB terintegrasi berbasis WEB berdasarkan kebutuhan dan keinginan dari pengguna sistem. Disarankan kepada Dinas Kesehatan Kabupaten Sintang untuk membangun sistem yang sudah dirancang berdasarkan kebutuhan dari pengguna sistem sehingga permasalahan Sistem Informasi TB bisa diatasi.
Emotional intelligence in Belva Plain’s Blessings
Authors: Indriyani Nori , Munfangati Rahmi 
Published: September 2019

Everyone faces emotional challenges. It can influence their behavior since emotion is an incredibly strong drive on human behavior. This powerful emotion can lead someone to take actions that he might not regularly do, or keep away from the conditions that someone enjoys. Emotionality is related to a range of psychological phenomena, including mood, temperament, personality, and motivation. The ability to control emotions in the self and others is called Emotional Intelligence (EI). EI can be found not only in real life but in literary works such as a novel. In line with that interesting topic, this article, therefore, explores the EI and the implications of EI of the main character in Belva Plain’s Blessings. In analyzing the novel, the study applied a psychological approach. The technique of analyzing the data was a qualitative descriptive method. The findings of the study showed Jennie’s EI, that is composed of emotional self-awareness, self-regulation, motivation, and social skills. Furthermore, the results revealed the implications of Jennie’s EI; she becomes successful because she is good at self-regulation and motivation. She is also good at self-awareness, empathy and social skills, so she has better interpersonal relations.
YETENEK YÖNETİMİ VE ÖRGÜTSEL KARİYER YÖNETİMİ İLİŞKİSİ: FARKLI SEKTÖRLERDE BİR UYGULAMA
Authors: KARCIOĞLU Fatih , BAKAN ATASEVER Sibel 
Published: September 2019

Yetenek yönetimi ve kariyer yönetimi, insan kaynakları yönetimi alanında iddialı bir disiplindir. Yetenek yönetimi kavramının ilişkilendirildiği kavram olan örgütsel kariyer yönetimi, örgütlerin başarı elde etmesinde ve daha güçlü çalışan takımı kurmasında yetenek yönetimine yardımcı olan bir kavramdır. Bu iki kavram birbiriyle yakından ilişkilidir. Bu araştırmanın amacı, yetenek yönetimi ve örgütsel kariyer yönetimi ilişkisini belirlemektir. Bu nedenle aradaki ilişkiyi belirlemek için ankete dayalı araştırma yapılmıştır. Banka ve GSM sektöründe görev alan 234 çalışana yetenek yönetimi ve örgütsel kariyer yönetimi ile ilgili sorular yöneltilerek yetenek yönetimi ve örgütsel kariyer yönetimi arasındaki ilişki belirlenmiştir. Araştırmada yetenek yönetimi ve örgütsel kariyer yönetimi arasında anlamlı ilişkinin olup olmadığı korelasyon analizi ile demografik özellikler ile yetenek yönetimi ve örgütsel kariyer yönetimi arasında anlamlı farklılığın olup olmadığı ise t-testi ve Anova ile ölçülmüştür. Araştırma sonucunda, yetenek yönetimi ve alt boyutları ile örgütsel kariyer yönetimi alt boyutları arasında pozitif yönde anlamlı bir ilişki bulunmuştur. Demografik özellikler ile yetenek yönetimi ve örgütsel kariyer yönetimi arasında anlamlı fark bulunamamıştır.
Base Deficit as a Predictor of Mortality in Sepsis and Septic Shock
Authors: Bhusal Laxman , Prasad Pratap Narayan , Shakya Yogendra Man , Acharya Ramesh Prasad 
Published: September 2019

Introduction: Sepsis is a common problem encountered in emergency room which needs to be intervened early. It is always difficult to have quick prognostic marker of sepsis in busy emergency. So this study was conducted to determine whether base deficit can be used as an indicator of mortality among septic patients in emergency room setup like ours.
Methods: It was a hospital based descriptive cross sectional study done at Tribhuvan University Teaching Hospital, Kathmandu from March 2018 to December 2018. Acute physiology and chronic health Evaluation II score (APACHE II), Base deficit, Sequential Organ Failure Assessment (SOFA) score on first day of arrival in emergency room was calculated. The association of 28-day outcome with acute physiology and chronic Health Evaluation II score, Base deficit value and SOFA score were derived.
Results: Out of 229 patients with septic shock 62 died (27%) and among 71 patients without septic shock, 12 died (16.9%).Overall mortality was 24.66 % (n= 74).The area under the ROC curve for Base deficit(0.864;95% C.I.=0.822-0.906), APACHE II (0.782; 95% C.I=0.718-0.848, SOFA (0.689;95% C.I=0.620-0.757) were greater than 0.7 except for SOFA which signifies these test to have fair efficacy to predict mortality.
Conclusions: High base deficit value predicts mortality in patients with sepsis and septic shock. The base deficit could be used as an alternate marker to predict mortality in septic patient. We recommend for large multicenter study with randomization so that the findings can be applied to general population and of different geographical situations.
Clinical Presentations of Chronic Kidney Disease Patients on Regular Haemodialysis Attending in Tribhuvan University Teaching Hospital Emergency Services
Authors: Shrestha Tirtha Man , Prasad Pratap Narayan , Bhusal Laxman , Neupane Ram Prasad , Ghimire Rajan 
Published: September 2019

Background: Chronic kidney disease is increasing day by day and so is condition of renal replacement therapy mainly hemodialysis. Emergency visit of the patients under maintenance hemodialysis is frequent. The objective of the study is to study clinical parameters of these patients so that in future these deranged parameters can be focused during patient management and decrease their emergency visit.
Methods: A prospective cross sectional study was conducted in emergency services of Tribhuvan University Teaching Hospital from 1st May 2018 to 31st October 2018 among the adult chronic kidney disease patients under maintenance hemodialysis. Ethical approval was taken from Institutional review board, Institute of Medicine, Tribhuvan University. Non-probability sampling method was used. Total of 300 patients were enrolled in the study. Patients’ age, sex, causes, laboratory parameter during emergency visit, need of emergency hemodialysis, and need of blood transfusion were studied.
Results: Out of total 300 patients, mean age was 45.64 years (S.D =17.15). 190 (63.3 %) were male and 110(36.70%) were female. 152(50.70%) of patients had hypertension.Diabetes and Glomerulonephritis both had equal prevalence of 63(21%). Mean hemoglobin was 6.52gm% (S.D = 1.93). Mean pH was 7.17 (S.D =0.154). Mean serum potassium and creatinine level were 5.77 mEq/L (S.D =0.76) and 1076.03 mmol/l (S.D =367.25) respectively. Area under the Receiver Operating Curve was 0.660 for potassium and 0.598 for serum creatinine.
Conclusion: Causes of chronic kidney disease, decreased hemoglobin level, increased serum creatinine and potassium level and metabolic acidosis are reasons of frequent emergency room visit among CKD patients. So these conditions need to be addressed to decrease emergency visit of these patients
Prevalence of HIV, Syphilis, Hepatitis-B, and Hepatitis-C among People with Injecting Drugs in Western Terai Highway districts, Nepal
Authors: Paudel Tarun , Rawal Bir , Deuba Keshab , Kakchapati Sampurna , Amgain Kapil , Sanjel Seshananda 
Published: September 2019

Introduction: HIV epidemic has become the major problems among people with injecting drugs (PWIDs) in Nepal. The study was carried out to assess the prevalence of sexually transmitted diseases including HIV/AIDS among PWIDs.
Methods: This descriptive cross-sectional survey was conducted in male PWIDs of age more than 16 years residing in Western to Far West Terai Districts of Nepal who had been injecting drugs for three months prior to the date of the survey" March-April 2017. A two-stage cluster sampling was used to recruit 300 PWIDs from seven Districts. HIV was diagnosed by using standard techniques approved by WHO. Similarly, Syphilis was tested using the "Rapid Plasma Reagin" and Hepatitis C as well as Hepatitis B was tested by using rapid test kits. Demographic data were collected by using structured questionnaire and the data obtained were entered in MS excel was transformed into the SPSS version 21 for the descriptive as well as inferential analysis.
Results: Prevalence of HIV, HBV, HCV, and STI among PWIDs were 5.3%, 2.7%, 23.7%, and 2.0% respectively. Majority of the PWIDs were literate (93.7%) and their age was below 35
years. Among the married PWIDs, 32.4% had got married before the age of 19. Similarly, 53.7% of them were living with their female sexual partner, and 95.0% were living with their wife. Ninety six percent of the respondents reported to be ever involved in sexual activity, 77.1% of them initiated the sexual intercourse before the age of 20 years and 41.9% of them had more than one female sexual partner. The survey indicated that 36.3% had been injecting drugs for more than 5 years while 27.7% had been injecting for last 2-5 years and 55.0% of the respondents had injected for the first time at the age of 16-24 years. About one in 10 respondents had started injecting drugs recently.
Conclusion: There is high prevalence of HIV, HCV, HBV and active syphilis among the PWIDs. Co-infection of HIV and HCV as well as Hepatitis B and C were also prevalent among PWIDs. Comprehensive education and awareness program is required to reduce the prevalence.
Adolescent Pregnancy and its Outcome in a Rural Teaching Hospital, Karnali Academy of Health Science, Jumla
Authors: Rai Purnima , Sindan Namrata , Acharya Bishnu Dutta , Shah Rajiv , Shrestha Sandeep 
Published: September 2019

Introduction: Nepal is a low socioeconomic country and adolescent pregnancy can have deleterious effects on health as well as social wellbeing of the mother, child and the community. The aim of this study was to find the frequency of teenage pregnancy and its outcomes in Karnali Academy of Health Science.
Method: This was a retrospective study conducted in Karnali Academy of Health Science, Jumla, Nepal. Data was collected from the hospital records from October 2017 to September 2018.
Result: The frequency of teenage pregnancy was 22.6% among total deliveries. Most of them were primigravida (84.9%). Majority of them were 18 years of age (47.5%). Caesarean section accounted for 10.8%. In perinatal outcome, the incidence of preterm birth was 15.1%, and extremely low birth weight was 2.2%, very low birth weight was 1.4% and low birth weight was 12.2%. Maternal complication accounted for 33.09%.
Conclusion: The study concluded that frequency of teenage pregnancy is considerably high and it is associated with increases risk of adverse outcome to both mother and newborn such as intrauterine fetal death, retained placenta, and malpresentations. Therefore, education and awareness can be helpful in reducing adolescent pregnancy and its adverse outcomes.
Nurses Knowledge on Management of Patient Receiving Spinal Anaesthesia in a Government Hospital
Authors: Rijal Elisha , Silwal Suvekshya , Thapa Sheela , Basnet Saraswati , Bhagat Subhadra 
Published: September 2019

Introduction: Spinal Anaesthesia (SA) is a form of regional anaesthesia involving injection of a local anaesthetic into the subarachnoid space. SA is directly related to nervous system, so its mismanagement may cause various complications hence, prevention and management of complication is a vital and complex aspect of critical nursing care. Therefore, the objective of this study was to assess the nurse’s knowledge on the management of patient receiving spinal anaesthesia.
Methodology: A cross-sectional descriptive study was conducted among nurses of Koshi Zonal Hospital of Province no. 1, Biratnagar, Nepal from May to June 2017. Non-probability purposive sampling method was used where self-administered questionnaire was administered among 67 working nurses in the hospital.
Results: The majority of the respondents (77.6%) belonged to 20-30 years of age group, nearly half (44.8%) of the respondents had completed PCL nursing. Only 67.2% explained the meaning of anaesthesia, and 58.2% had knowledge on physiological changes after SA. Regarding ambulation and cause of backache, 29.9% had knowledge whereas only 20.9% had knowledge about management of post spinal backache. Respondents facing problem to manage the complication after SA was 13.4%. This study also found that the overall knowledge regarding SA was adequate among 80.6% respondents.
Conclusion: Nurses as the key personnel in management and prevention of complication, the obtained result was below the desired competence level among working nurses as it is the vital aspect of critical nursing care.
Comparison of High Resolution Computed Tomography with Intraoperative Findings in Patient with Chronic Suppurative Otitis Media, NAMS, Bir Hospital, Kathmandu, Nepal
Authors: Rokaya Yagya Bahadur , Shahi Prakash 
Published: September 2019

Introduction: Chronic suppurative otitis media (CSOM) is an important cause of middle ear disease and its complications challenge both otologist and radiologist. The major benefit of HRCT is an excellent visualization of the osseous structure by means of special algorithms. This study compares the HRCT with intraoperative findings in patients with CSOM.
Methods: This is an observational descriptive study conducted at NAMS Bir Hospital. Total of 30 patients, referred for HRCT from the department of ENT were studied. Comparison of HRCT findings was done with intraoperative findings regarding the status of EAC, ossicular chain, bony plate, inner ear structure and facing nerve canal was done, considering intraoperative findings as the gold standard.
Results: Out of 30 patients, 16 patients had CSOM with cholesteatoma and 14 patients had CSOM without cholesteatoma. HRCT presented sensitivity, specificity, positive predictive value, negative predictive value and accuracy of 87.5%, 85.7%, 87.5%, 85.7% and 86.7% respectively in diagnosing CSOM with cholesteatoma. HRCT presented sensitivity and specificity of 85.7% and 87.5% in identification of malleus erosion, sensitivity and specificity of 86.7% and 80%, in the identification of incus erosion. HRCT showed the specificity of 85% with relatively low sensitivity of 70% in identification of erosion of stapes. HRCT showed a sensitivity of 100% and specificity of 85.7%. HRCT presented sensitivity and specificity of 83.3% and 95.8% in diagnosing tegmen tympanum erosion. HRCT showed the highest sensitivity (100%) and specificity (100%) in diagnosing erosion of sigmoid sinus plate and mastoid cortex. HRCT showed relatively low sensitivity of 66.7% and 75% in diagnosing erosion of LSCC and facial canal respectively. HRCT detected soft tissue mass in the middle ear/mastoid in all 30 patients of CSOM. Hence, the sensitivity, specificity, positive predictive value and negative predictive value of HRCT for soft tissue mass in the middle ear and mastoid, all were 100%.
Conclusion: The HRCT has a valuable role in preoperative evaluation of a case of CSOM. It has high sensitivity in diagnosing CSOM with cholesteatoma. However, HRCT has relatively low sensitivity for LSCC and facial nerve canal erosion.
Anesthetic Management of Humerus Fracture with Multiple Trauma and Pneumothorax
Authors: Gyawali Nirmal Kumar , Sharma Prastuti 
Published: September 2019

Background: Trauma is a significant health problem and a leading cause of death in all age group.
Methodology: In this study we describe anesthetic management of poly trauma with pneumthorax in a 55 years old male with humerus fracture.
Result: Patient with multiple trauma with pneumothorax was safely anaesthesized with regional anesthesia. This procedure also prevented progression of pneumothorax to tension pneumothorax.
Conclusion: Regional anesthesia is a safe alternative of general anesthesia in case of patient with pneumothorax for the upper limb surgery.