bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advance care planning with chronically ill patients: A relational autonomy approach
Authors: Killackey Tieghan , Peter Elizabeth , Maciver Jane , Mohammed Shan 
Published: May 2019

Advance care planning is a process that encourages people to identify their values, to reflect upon the meanings and consequences of serious illness, to define goals and preferences for future medical treatment and care, and to discuss these goals with family and health-care providers. Advance care planning is especially important for those who are chronically ill, as patients and their families face a variety of complex healthcare decisions. Participating in advance care planning has been associated with improved outcomes; yet, despite over 25 years of public awareness campaigns, research, and interventions developed to increase participation, advance care planning completion rates for people with chronic illnesses are no different than those in the general public (approximately 25%). Advance care planning has traditionally used an individualistic approach to autonomy, which puts forward an understanding of agents as independent, rational and self-interested persons. Because this individualistic approach has been largely unsuccessful in improving advance care planning uptake, a re-examination of the philosophical underpinnings of this practice and an exploration of alternative frameworks is warranted. In offering this exploration, we briefly outline two current perspectives on autonomy: the individualistic view and the relational view as articulated by feminist philosophers. Using a critical examination of the theoretical and empirical work on this topic, we argue that the individualistic view of autonomy does not sufficiently capture the relational and social complexities of the decision-making process of advance care planning. To offer a counterpoint, we examine the relational view of autonomy and suggest that this perspective is better aligned with the process of advance care planning. Specifically, we demonstrate that a relational model of autonomy is well suited to exploring advance care planning for four main reasons: (1) it recognizes the importance of relationships, (2) it reflects the fluctuating nature of autonomy in chronic illness, (3) it recognizes vulnerability, and (4) it is consonant with empirical work examining the advance care planning process.
Radiosurgical, neurosurgical, or no intervention for cerebral cavernous malformations: A decision analysis
Authors: Rinkel Leon A , Salman Rustam Al-Shahi , Rinkel Gabriel JE , Greving Jacoba P 
Published: May 2019

Introduction We aimed to evaluate the preferred treatment strategy for patients with symptomatic cerebral cavernous malformations (CCM). Methods In a decision model, we compared neurosurgical, radiosurgical, and conservative management. A literature review yielded the risks and outcomes of interventions, intracerebral hemorrhage (ICH), and seizures. Patients with CCM rated their quality of life to determine utilities. We estimated the expected number of quality-adjusted life years (QALYs) and the ICH recurrence risk over five years, according to mode of presentation and CCM location (brainstem vs. other). We performed analyses with a time horizon of five years. Results Using the best available data, the expected number of QALYs for brainstem CCM presenting with ICH or focal neurological deficit was 2.84 (95% confidence interval [CI]: 2.54–3.08) for conservative, 3.01 (95% CI: 2.86–3.16) for neurosurgical, and 3.03 (95% CI: 2.88–3.18) for radiosurgical intervention; those for non-brainstem CCM presenting with ICH or focal neurological deficit were 3.08 (95% CI: 2.85–3.31) for conservative, 3.21 (95% CI: 3.01–3.36) for neurosurgical, and 3.19 (95% CI: 2.98–3.37) for radiosurgical intervention. For CCM presenting with epilepsy, QALYs were 3.09 (95% CI: 3.03–3.16) for conservative, 3.33 (95% CI: 3.31–3.34) for neurosurgical, and 3.27 (95% CI: 3.24–3.30) for radiosurgical intervention. Discussion and conclusion For the initial five years after presentation, our study provides Class III evidence that for CCM presenting with ICH or focal neurological deficit conservative management is the first option, and for CCM presenting with epilepsy CCM intervention should be considered. More comparative studies with long-term follow-up are needed.
Recent advances in the science and technology of natural zeolites in Iran
Authors: Behin Jamshid , Ghadamnan Elmira , Kazemian Hossein 
Published: May 2019

AbstractIran has significant deposits of high-purity natural zeolites. Many Iranian scholars conduct scientific research on porous materials, from natural and synthetic zeolites to metal organic framework materials. Iranian zeolite deposits and associated research are reviewed here. Various industrial applications of natural zeolites, from agriculture to animal husbandry to the construction industry and beyond are discussed here.
Defect and temperature effects on the mechanical properties of kaolinite: a molecular dynamics study
Authors: Yang H. , Han Z.F. , Hu J. , He M.C. 
Published: May 2019

AbstractMolecular dynamics simulations of different defective kaolinites under tension were performed to reveal the effects of defect location, type, density and temperature on their mechanical properties. Four types of defective kaolinite with Si vacancies were constructed. Based on the atomic-scale deformation and failure processes of defective kaolinite and its stress–strain curves, the Young's moduli and tensile strengths in three crystal directions were obtained and compared with the existing theoretical values from the literature. The defect location at each layer does not affect the mechanical properties of kaolinite and the cracks initiated at the defective sites. The atom density of each model was calculated in order to investigate the defect-type effect on the mechanical properties of kaolinite. The simulation results also showed that kaolinite exhibits brittle failure behaviour and the mechanical properties degrade significantly with increasing defect density and temperature. The influence of temperature on the mechanical properties of defective kaolinite is discussed in detail.
The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells
Authors: Lan Xianjiang , Khandros Eugene , Huang Peng , Peslak Scott A. , Bhardwaj Saurabh K. , Grevet Jeremy D. , Abdulmalik Osheiza , Wang Hongxin , Keller Cheryl A. , Giardine Belinda , Baeza Josue , Duffner Emily R. , El Demerdash Osama , Wu Xiaoli S. , Vakoc Christopher R. , Garcia Benjamin A. , Hardison Ross C. , Shi Junwei , Blobel Gerd A. 
Published: May 2019

Abstract
Reactivation of fetal hemoglobin (HbF) production benefits patients with sickle cell disease and β-thalassemia. To identify new HbF regulators that might be amenable to pharmacologic control, we screened a protein domain–focused CRISPR-Cas9 library targeting chromatin regulators, including BTB domain–containing proteins. Speckle-type POZ protein (SPOP), a substrate adaptor of the CUL3 ubiquitin ligase complex, emerged as a novel HbF repressor. Depletion of SPOP or overexpression of a dominant negative version significantly raised fetal globin messenger RNA and protein levels with minimal detrimental effects on normal erythroid maturation, as determined by transcriptome and proteome analyses. SPOP controls HbF expression independently of the major transcriptional HbF repressors BCL11A and LRF. Finally, pharmacologic HbF inducers cooperate with SPOP depletion during HbF upregulation. Our study implicates SPOP and the CUL3 ubiquitin ligase system in controlling HbF production in human erythroid cells and may offer new therapeutic strategies for the treatment of β-hemoglobinopathies.
Exploring stigma and its effect on access to mental health services in unaccompanied refugee children
Authors: Majumder Pallab 
Published: May 2019

Aims and methodDespite substantial evidence to show that unaccompanied refugee children suffer a high prevalence of mental illness, their access to services remains poor. One may hypothesise that this is associated with their negative perceptions of mental illness. However, there has been little research exploring this important subject. We aimed to explore unaccompanied refugee children's experiences, perceptions and beliefs of mental illness, focusing on stigma. Fifteen unaccompanied refugee children and 15 carers were interviewed by a semi-structured interview. Thematic analysis was used to analyse data.ResultsThree main themes were identified, focusing mainly on issues of stigma related to mental health, mental illness and their treatment, and they were interpreted in detail.Clinical implicationsOur findings will contribute to current understanding of stigma and discrimination, and their effect on service engagement, and will hopefully stimulate interest to further explore this area and develop potential solutions.
Archive Filmaria
Authors: Siddique Salma 
Published: May 2019

Abstract
This essay examines the missing national film archive of Pakistan against the politics of competing cultural memory. Sharing a common past yet existing in the shadows of the Indian film industry, cinema in Pakistan found itself in an unusual predicament after decolonization and Partition. While filmmaking was expected to carry the imprint of national difference, the intercultural context of colonial India bequeathed the industry its traditions and personnel. Yet when the British Film Institute repatriated colonial Indian films in the mid-1960s, the holdings went entirely to India. The lack of a public film repository denied Pakistan not only its colonial heritage but also the systematic preservation of its postcolonial film culture. In the absence of a state archive, what has emerged in the country is a democratic archive consisting of independent collectors, magazine proprietors, and avid users. Using a term extracted from one of the archives, filmaria (film fever), Siddique reads in the popular film archives the contagious circumstances of intercultural cinema. It alerts us to a film contagion widespread in the subcontinental publics that thrives on filmgoing, cinematic resemblance, and embodied cultural memory, a condition caused by the displacements of Partition and the creation of national difference.
Stochastic single cell migration leads to robust horizontal cell layer formation in the vertebrate retina
Authors: Amini Rana , Labudina Anastasia A. , Norden Caren 
Published: May 2019

ABSTRACT
Developmental programs that arrange cells and tissues into patterned organs are remarkably robust. In the developing vertebrate retina, for example, neurons reproducibly assemble into distinct layers giving the mature organ its overall structured appearance. This stereotypic neuronal arrangement, termed lamination, is important for efficient neuronal connectivity. Although retinal lamination is conserved in many vertebrates, including humans, how it emerges from single cell behaviour is not fully understood. To shed light on this issue, we here investigated the formation of the retinal horizontal cell layer. Using in vivo light sheet imaging of the developing zebrafish retina, we generated a comprehensive quantitative analysis of horizontal single cell behaviour from birth to final positioning. Interestingly, we find that all parameters analysed, including cell cycle dynamics, migration paths and kinetics, as well as sister cell dispersal, are very heterogeneous. Thus, horizontal cells show individual non-stereotypic behaviour before final positioning. Yet these initially variable cell dynamics always generate the correct laminar pattern. Consequently, our data show that the extent of single cell stochasticity in the lamination of the vertebrate retina is underexplored.
Effect of storage time on the properties of faeces
Authors: Pandarum Sameshan , Ramkalawan Yatish , Velkushanova Konstantina V. , Jingxi Estella Zandile , Foxon Katherine Maria 
Published: May 2019

Background: This short-term study was carried out in 2013 at the Pollution Research Group at the University of KwaZulu-Natal (Durban, South Africa) as an asisgnemnt of a final year Chemical engineering student project. It focussed on the effect of storage time on the properties of fresh human faeces, more particularly moisture content, thermal conductivity, volatile solids and chemical oxygen demand (COD). These properties are important as they are often used in the design of drying or thermal treatment technologies for faeces. A storage period of one week was hypothesised at room ambient temperature. Methods: The samples were tested for chemical properties using standard operational procedures developed at the Pollution Research Group with parameters such as totals solids, moisture content, suspended solids, volatile solids, COD and thermal conductivity. Results: The thermal conductivity on average was 0.44 W/m.K. The moisture content was observed to decrease by 16%, from 77% to 61%. Thermal conductivity was plotted over the range of moisture contents to observe any trends, varying from 0.074 W/m.K to 0.61 W/m.K for dry faeces and water respectively. The use of a composition weighted average model fitted the data well and was found to be within 95% of the confidence interval of the best fit line. Conclusions: The effect of storage time was found to be negligible on COD and thermal conductivity however moisture content decreased as days progressed and the volatile solids increased with an increase in storage time. Examining the relationship between thermal conductivity and moisture content, it was found that thermal conductivity increase with an increase in moisture content.
Could trained providers provide better quality of IUD services? Results of a secondary data analysis of complications as a proxy indicator
Authors: Gehani Manish , Pal Manoj , Arya Anupama , Singh Shobhana , S. Kaushik , O’Connell Kathryn A. , Cagatay Levent , Sengupta Sumon , Singal Sunita 
Published: May 2019

Background: For accelerating its progress towards FP2020 goals, the Government of India has focused on improving the quality of intrauterine device (IUD) services. EngenderHealth has supported the Governments of Rajasthan and Gujarat since 2014 through its Expanding Access to IUD Services in India (EAISI) project by building the capacity of service providers, monitoring their compliance with standard practices, and strengthening health systems. This study sought to assess whether EAISI trained providers provide a better quality of IUD services as compared to non-EAISI trained providers, as indicated by a reduction in confirmed IUD complications? Methods: This study was an analytical cross-sectional study of secondary data collected from the follow-up registers of 176 intervention facilities (138 in Rajasthan and 38 in Gujarat) during Phase I of EAISI project. The analysis included clients who returned between April 2018 and March 2019 to the same facility for a follow-up visit. Multivariate logistic regression was performed to determine factors associated with IUD complications. Results: A total of 56,733 IUD insertions were conducted, and 10,747 (18.9%) client follow-ups were documented. Of these, 49.4% (N=5,305) clients received IUDs from EAISI-trained providers, while 50.6% (N=5,442) received IUDs from non-EAISI trained providers. A total of 4.0% (N=432) of clients experienced complications (Expulsion: 1.3%, Missing Strings: 1.7%, Infection: 1.1%). Clients who received IUDs from non-EAISI-trained providers were 55.5% more likely [95% CI (26.2%, 91.5%), p<0.0005] to have complications compared to clients who received insertions from EAISI-trained providers. Other significant factors include the type of IUD, timing of the follow-up visit and timing of the insertion. Conclusion: The findings demonstrate that intensive, hands-on training of providers to improve clinical skills for IUD insertions can have a positive impact on the reduction of post-insertion complications.
The spectral interior: Gender and representations of household objects in the work of three Chinese artists
Authors: Liu Mengyao 
Published: May 2019

Both obscured by and submerged in the widely accepted chronology of China’s seemingly frictionless entrance into capitalist modernity, the history of Chinese socialist feminism haunts the present moment. In their subjective and circuitous quality, imbued in specific moments or materials as opposed to developing in a linear fashion, memories contain the potential to reread the present. Drawing from Tani Barlow’s formulation of Chinese feminism as operating in the ‘future anterior’ tense, this article examines the work of three contemporary Chinese visual artists whose works explore the memory of maternal figures through their portrayals of household objects. The first installation, Song Dong’s Waste Not, meticulously assembles five decades worth of family possessions taken from his mother’s Beijing home. Song’s installation underscores such objects as out of place in the present moment, existing beyond their projected use-value. Embroidered sculptures of household items comprise the second installation, Gao Rong’s The Static Eternity. The materiality of Gao’s work makes the intersection of gendered labour, artistry and reproduction visible. Her choice of medium stands in critical comparison to contemporary valuations, which prioritizes product over process. The third installation is Dong Yuan’s A Short History of Everything: Grandmother’s House and Bosch’s Garden, an exhibition made up of photorealistic oil paintings. Her work depicts ordinary kitchenware, furniture and decorations juxtaposed with her isolated replications of Hieronymous Bosch’s surrealist creatures. This combination reflects contemporary understandings of China’s socialist feminist history, represented by her grandmother’s belongings, as imagined and aberrant. But Dong’s work attests to just how fruitlessly the constructed present attempts to cast off its phantoms.
Taken together, the works of these three artists constitute a refusal to depoliticize the quotidian, critiquing a surrender to the lure and logic of endless capital accumulation. This article assesses the urgency and stakes of such an endeavour in postsocialist Chinese visual art.
Lignosulfonate-based polyurethane materials via cyclic carbonates: preparation and characterization
Authors: Mimini Vebi , Amer Hassan , Hettegger Hubert , Bacher Markus , Gebauer Ireen , Bischof Robert , Fackler Karin , Potthast Antje , Rosenau Thomas 
Published: May 2019

AbstractUsage of lignin and its derivatives as chemical and carbon source, i.e. in processes other than burning, is one of the most active fields in renewable resource chemistry today. In this study, the synthesis of lignosulfonate (LS)-based polyurethane (PU) materials from non-toxic reagents and through environmentally friendly processes is presented. LS, modified with bio-based (glycerin-derived) cyclic carbonate moieties, was reacted with 1,6-hexamethylenediamine (HMDA) to form characteristic PU material. For mechanistic studies and reaction optimization, cyclic carbonates and 1,2-diol derivatives of vanillyl alcohol (VA), as a simplifying lignin model compound, were employed. An LS-bound cyclic carbonate can be formed in one pot without a transesterification step, which simplifies the route toward non-isocyanate lignin-based PU materials. Attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectra showed typical linkages of cyclic carbonates and 1,2-diols on LS. Further analytical characterization, in both the model compound and the LS polymer case, was provided by liquid-state nuclear magnetic resonance (NMR) spectroscopy [one-dimensional (1D), two-dimensional (2D) and 31P] and 13C solid-state (ss) NMR. The production of PU materials from sulfonated lignin and glycerol carbonate, synthesized through a non-isocyanate reaction pathway, confirms the good potential of LS utilization in the development of PU composites based on renewable resources.
Psychosocial determinants of stress among adolescents in an urban slum in a city of Western Maharashtra: a cross-sectional study
Authors: Aishwarya C.S. , Samanta Indranil , Dudeja Puja 
Published: May 2019

AbstractIntroductionStress is a major underlying factor in the manifestation of many mental disorders. The prevalence of stress among Indian adolescents varies from 13% to 45%. Hence, the present study was done to assess the psychosocial determinants of stress among adolescents in an urban slum.MethodologyThis was a cross-sectional analytical study (community based) in an urban slum from January to July 17 with a sample of 230 adolescents aged 10–19 years. An Indian Council of Medical Research (ICMR) tool validated for use in the community was self-administered. Data was analyzed using SPSS 20.0.ResultsThe commonest stressors were perceived threat to economic position (84.3%), economic difficulty of meeting expenses for treatment of self/family members (63.5%), upcoming exams (61). The stressors that occurred significantly more often (p < 0.05) in males as compared to females were related to sexual desire, conflicts in love affairs, getting a job/employment issues, exam failure and interpersonal relationships within the family. Stressors that occurred significantly more often (p < 0.05) in females than in males were fear of sexual abuse/assault. Significant correlates of the presence of stress were male gender, nuclear family and low family income (p < 0.05).ConclusionThe stressors in adolescents in an urban slum are both internal and external. There are gender differentials in type of stressors faced by adolescents.
Asymptotically periodic behavior of solutions of fractional evolution equations of order 1 < α < 2
Authors: Ren Lulu , Wang Jinrong , O’Regan Donal 
Published: May 2019

Abstract
In this paper we investigate the asymptotically periodic behavior of solutions of fractional evolution equations of order 1 < α < 2 and in particular existence and uniqueness results are established. Two examples are given to illustrate our results.
On the polynomial entropy for morse gradient systems
Authors: Katić Jelena , Perić Milan 
Published: May 2019

Abstract
We adapt the construction from [HAUSEUX, L.—LE ROUX, F.: Polynomial entropy of Brouwer homeomorphisms, arXiv:1712.01502 (2017)] to obtain an easy method for computing the polynomial entropy for a continuous map of a compact metric space with finitely many non-wandering points. We compute the maximal cardinality of a singular set of Morse negative gradient systems and apply this method to compute the polynomial entropy for Morse gradient systems on surfaces.
A note on non-linear ∗-Jordan derivations on ∗-algebras
Authors: Taghavi Ali , Nouri Mojtaba , Razeghi Mehran , Darvish Vahid 
Published: May 2019

Abstract
Taghavi et al. in [TAGHAVI, A.—ROHI, H.—DARVISH, V.: Non-linear ∗-Jordan derivations on von Neumann algebras, Linear Multilinear Algebra 64 (2016), 426–439] proved that the map Φ: 𝓐 → 𝓐 which satisfies the following condition

Φ
(
A
⋄
B
)
=
Φ
(
A
)
⋄
B
+
A
⋄
Φ
(
B
)

$$\begin{array}{}
\Phi(A\diamond B)=\Phi(A)\diamond B+A\diamond \Phi(B)
\end{array}
$$

where A ⋄ B = AB+BA
* for every A, B ∈ 𝓐 is an additive ∗-derivation. In this short note, we prove that when A is a prime ∗-algebras and Φ: 𝓐 → 𝓐 satisfies the above condition, then Φ is ∗-additive. Moreover, if Φ(iI) is self-adjoint then Φ is derivation.
Crystal structure of 2-(3-methoxyphenyl)-3-((phenylsulfonyl)methyl)imidazo[1,2-a]pyridine, C21H18N2O3S
Authors: Mi Xia , Zhong Zheng , Yang Jing , Zhang Jingyu 
Published: May 2019

Abstract
C21H18N2O3S, monoclinic, P21/n (no. 14), a = 12.1263(2) Å, b = 11.6913(3) Å, c = 12.7643(3) Å, β = 92.340(2)°, V = 1808.11(7) Å3, Z = 4, R
gt(F) = 0.0433, wR
ref(F
2) = 0.1310, T = 293(2) K.
5-Methyl-N′-[5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazole-4-carbonyl]-1-(4-methylphenyl)-1H-1,2,3-triazole-4-carbohydrazide, C22H22N8O2
Authors: Aldosari Obaid Fahad , Abdel-Wahab Bakr F. , Alotaibi Mohammad Hayal , Hegazy Amany S. , Kariuki Benson M. , El-Hiti Gamal A. 
Published: May 2019

Abstract
C22H22N8O2, monoclinic, P21/c (no. 14), a = 15.5175(5) Å, b = 7.9715(3) Å, c = 17.3941(5) Å, β = 90.005(3)°, V = 2151.61(12) Å3, Z = 4, R
gt(F) = 0.0592, wR
ref(F
2) = 0.1780, T = 293(2) K.