bluuebunny/crossref_metadata_2025_split huggingface dataset:
O DIREITO E OS DIREITOS HUMANOS FRENTE À NANOTECNOLOGIA NA SOCIEDADE COMPLEXA DE RISCO E GLOBAL
Authors: Berwig Juliane Altmann , Engelmann Wilson 
Published: August 2019

O presente artigo objetiva abordar os Direitos Humanos nas suasdimensões evolutivas e a sua relação com as novas tecnologias, especialmente a nanotecnologia. Neste sentido, dentre as dimensões dos Direitos Humanos, a Terceira está sendo desafiada a compreender suas facetas diante das inúmeras inovações nanotecnológicas em uma sociedade de risco e global. Ao mesmo tempo, o tradicional Direito está sendo criticado a transformar-se, sendo capaz de acompanhar as evoluções tecnológicas e resguardar os riscos humanos e ambientais. Diante disso, o artigo se utilizará da pesquisa bibliográfica comometodologia e da matriz sistêmico-construtivista para abordar os Direitos Humanos em suas dimensões e evoluções na sociedade de risco de Niklas Luhmann, a fim de demonstrar as etapas evolutivas das dimensões dos Direitos Humanos e sua relação com os riscos da nanotecnologia. Ao final, concluir-se-á que a resposta para a proteção dos Direitos Humanos aos riscos nanotecnológicos deve partir de uma discussão internacional e não isoladamente nacional, diante na sociedade global conectada. Para tanto, é necessário desafiar o Direito a partir das experiências globais, flexíveis e transdisciplinares.
O “ILUMINISMO CONSTITUCIONAL”: A ATUAÇÃO DO SUPREMO TRIBUNAL FEDERAL ENTRE A AUTOCONTENÇÃO E O ATIVISMO JUDICIAL
Authors: Forster João Paulo K. , Haeberlin Mártin 
Published: August 2019

O presente artigo busca compreender a noção de “iluminismoconstitucional” partindo da hipótese de que ela não possui caráter iluminista, na medida em que: (i) faz ressurgir a tensão clássica entre o ativismo e a autocontenção judicial; e (ii) retira dos textos o eixo da interpretação. Nessa visada, o artigo é dividido em duas partes, ambas desenvolvidas em pesquisa analítica com metodologia de revisão bibliográfica. Na primeira, analisa os conceitos de autocontenção e ativismo, examinando casos paradigmáticos em sistemas de common law, a fim de evitar sua simples transposição para o Brasil, considerandoas diferenças entre os sistemas. Na segunda, estuda o impacto de tais conceitos no Brasil, em particular no Supremo Tribunal Federal, igualmente expondo casos que caracterizam ativismo judicial. Ao final, conclui pela necessidade de distinção entre decisões de vanguarda estabelecidas dentro da multiplicidade de significados extraíveis naturalmente dos textos e das decisões cuja vanguarda advém de umapostura que, mesmo politicamente desejável, é juridicamente inaceitável, em razão de violar uma ética da leitura inerente à autolimitação judicial.
The Stoic Appeal to Expertise: Platonic Echoes in the Reply to Indistinguishability
Authors: Shogry Simon 
Published: August 2019

AbstractOne Stoic response to the skeptical indistinguishability argument is that it fails to account for expertise: the Stoics allow that while two similar objects create indistinguishable appearances in the amateur, this is not true of the expert, whose appearances succeed in discriminating the pair. This paper re-examines the motivations for this Stoic response, and argues that it reveals the Stoic claim that, in generating a kataleptic appearance, the perceiver’s mind is active, insofar as it applies concepts matching the perceptual stimulus. I argue that this claim is reflected in the Stoic definition of the kataleptic appearance, and that it respects their more general account of mental representation. I further suggest that, in attributing some activity to the mind in creating each kataleptic appearance, and in claiming that the expert’s mind allows her to form more kataleptic appearances than the amateur, the Stoics draw inspiration from the wax tablet model in Plato’sTheaetetus(190e–196d), where Socrates distinguishes the wise from the ignorant on the basis of how well they match sensory input with its appropriate mental ‘seal’ (σφραγίς).
Seneca on Human Rights inDe Beneficiis3
Authors: Long Alex 
Published: August 2019

AbstractThe paper discusses Seneca’s phrase ‘human rights’ (ius humanum) inOn Benefits3 and relates the passage to recent debates about human rights in Stoicism and ancient philosophy. I argue that the Latin phrase refers either to rights or to a law conferring rights. The difference between the passage and a common expectation for human rights lies in the kind of relation between right and duty. In Seneca’s passage the right does not in itself have a correlative duty on the part of other people, and yet it does, if exercised through benefactions, create a duty in others. By contrast, the relation between right and duty is usually expected to be unconditional.
Effects of ZnO addition on thermal properties, degradation and biocompatibility of P45Mg24Ca16Na(15−x)Znx glasses
Authors: Wang Yunqi , Zhu Chenkai , Parsons Andrew , Rudd Chris , Ahmed Ifty , Sharmin Nusrat 
Published: August 2019

Abstract
Four phosphate-based glass formulations in the system P45Mg24Ca16Na(15−x)Znx, referred to as P45Znx (x = 0, 5, 10 and 15 mol%), were prepared using a melt quenching process. The effect of ZnO addition on density, molar volume, thermal properties and degradation rates were studied. An increase in the glass transition, crystallisation, melting and liquidus temperatures were seen when replacing Na2O with ZnO. The molar volume of the bulk glasses was seen to decrease with increasing ZnO content. The dissolution rate of the zinc-free glass was 2.48 × 10−8 kg m−2 s−1 and addition of 5 mol% ZnO resulted in a reduction of the dissolution rate to 1.68 × 10−8 kg m−2 s−1. However, further addition of ZnO from 5 mol% to 15 mol% increased the dissolution rate of the glass system. The glasses were deliberately crystallised and XRD studies identified the Z n2P2O7 phase for glass code P45Zn5, and Zn(PO3)2 phase for P45Zn10 and P45Zn15 glasses. Cyto-compatibility studies were conducted using MG63 cells for 14 days. An overall increase in the metabolic activity and DNA concentration of cells was seen from day 1 to day 14 for all glass formulations investigated. However, increasing ZnO content from 0 to 15 mol% seemed to have a negative effect on the cellular activity. Interestingly, a remarkably higher ALP activity was seen at day 14 for glass codes P45Zn5 and P45Zn10 in comparison with the TCP control and the P45Zn0 glass.
Validation and standardization of the ETP-based activated protein C resistance test for the clinical investigation of steroid contraceptives in women: an unmet clinical and regulatory need
Authors: Douxfils Jonathan , Morimont Laure , Delvigne Anne-Sophie , Devel Philippe , Masereel Bernard , Haguet Hélène , Bouvy Céline , Dogné Jean-Michel 
Published: August 2019

Abstract

Background
Regulatory bodies recommend the use of an assay based on the assessment of the endogenous thrombin potential (ETP) for the investigation of the activated protein C resistance (APCr) in the development of steroid contraceptives in women. However, the assays described in the literature are home-made and not standardized regarding the method, the reagents, the reference plasma and the quality controls. In the absence of any commercially available method, we aimed at validating the ETP-based APCr assay.

Methods
The validation was performed according to regulatory standards. The method targets a 90% inhibition of the ETP in healthy donors in the presence of APC compared to the same condition in the absence of APC. As a large-scale production of a pool of plasma from well-selected healthy donors is impossible, algorithms were applied to a commercial reference plasma to correlate with the selected pool.

Results
Repeatability and intermediate precision passed the acceptance criteria. The assay demonstrated a curvilinear dose response to protein S and APC concentrations (R2 > 0.99). Analysis of plasma samples from 47 healthy individuals (22 women not taking combined hormonal contraceptives [CHC], and 25 men not Factor V Leiden carriers) confirmed the validity of the test, with a mean inhibition percentage of 90%. Investigations in 15 women taking different contraceptives and in two subjects with Factor V Leiden confirmed the good sensitivity and performance of the assay.

Conclusions
This validation provides the pharmaceutical industry, the regulatory bodies and physicians with a reproducible, sensitive and validated gold-standard ETP-based APCr assay.
Kinetics and Mechanistic Study of Hydrolysis of Adenosine Monophosphate Disodium Salt (AMPNa2) in Acidic and Alkaline Media
Authors: Sim Yoke-Leng , Kaur Beljit 
Published: August 2019

AbstractPhosphate ester hydrolysis is essential in signal transduction, energy storage and production, information storage and DNA repair. In this investigation, hydrolysis of adenosine monophosphate disodium salt (AMPNa2) was carried out in acidic, neutral and alkaline conditions of pH ranging between 0.30-12.71 at 60°C. The reaction was monitored spectrophotometrically. The rate ranged between (1.20 ± 0.10) × 10-7 s-1 to (4.44 ± 0.05) × 10-6 s-1 at [NaOH] from 0.0008 M to 1.00M recorded a second-order base-catalyzed rate constant, kOH as 4.32 × 10-6 M-1 s-1. In acidic conditions, the rate ranged between (1.32 ± 0.06) × 10-7 s-1 to (1.67 ± 0.10) × 10-6 s-1 at [HCl] from 0.01 M to 1.00 M. Second-order acid-catalyzed rate constant, kH obtained was 1.62 × 10-6 M-1 s-1. Rate of reaction for neutral region, k0 was obtained from graphical method to be 10-7 s-1. Mechanisms were proposed to involve P-O bond cleavage in basic medium while competition between P-O bond and N-glycosidic cleavage was observed in acidic medium. In conclusion, this study has provided comprehensive information on the kinetic parameters and mechanism of cleavage of AMPNa2 which mimicked natural AMP cleavage and the action of enzymes that facilitate its cleavage.
The Sanskruti index of trees and unicyclic graphs
Authors: Deng Fei , Jiang Huiqin , Liu Jia-Bao , Poklukar Darja Rupnik , Shao Zehui , Wu Pu , Žerovnik Janez 
Published: August 2019

AbstractThe Sanskruti index of a graphGis defined as$$\begin{align*}S(G)=\sum_{uv\in{}E(G)}{\left(\frac{s_G(u)s_G(v)}{s_G(u)+s_G(v)-2}\right)}^3, \end{align*}$$wheresG(u) is the sum of the degrees of the neighbors of a vertexuinG. LetPn,Cn,SnandSn+ebe the path, cycle, star and star plus an edge ofnvertices, respectively. The Sanskruti index of a molecular graph of a compounds can model the bioactivity of compounds, has a strong correlation with entropy of octane isomers and its prediction power is higher than many existing topological descriptors.In this paper, we investigate the extremal trees and unicyclic graphs with respect to Sanskruti index. More precisely, we show that(1)$\frac{512}{27}n-\frac{172688}{3375}\leq{}S(T)\leq{}\frac{(n-1)^7}{8(n-2)^3}$for ann-vertex treeTwithn≤ 3, with equalities if and only ifT ≌Pn(left) andT≌Sn(right);(2)$ \frac{512}{27}n\leq{}S(G)\leq{}\frac{(n-3)(n+1)^3}{8}+\frac{3(n+1)^6}{8n^3}$for ann-vertex unicyclic graph withn≥ 4, with equalities if and only ifG ≌Cn(left) andG≌Sn+e(right).
Fluorescence study of 5-nitroisatin Schiff base immobilized on SBA-15 for sensing Fe3+
Authors: Fahmi Muhammad Riza Ghulam , Fajar Adroit T.N. , Roslan Nurliana , Yuliati Leny , Fadlan Arif , Santoso Mardi , Lintang Hendrik O. 
Published: August 2019

AbstractN’-(5-nitro-2-oxoindolin-3-ylidene) thiophene-2-carbohydrazide (NH) was successfully synthesized as a ligand, then grafted onto the surface of mesoporous silica SBA-15via an aminopropyl bridge. The successful grafting of ligand NH onto the hybrid nanomaterial (SBA-15/APTES-NH) was confirmed by infrared spectroscopy. On excitation at 276 and 370 nm, the ligand NH and the hybrid nanomaterial SBA-15/APTES-NH showed a strong and narrow emission peak centered at 533 nm. By dispersing SBA-15/APTES-NH in an aqueous solution containing metal ions, the resulting solid materials showed a higher binding of NH sensing site to Fe3+ ions as compared to the others with a quench of the emission intensity up to 84%. This result showed that the hybrid nanomaterial is a potential chemosensor that requires development for the detection of metal ions.
Wandel und Variation der Genitivstellung in einem diachronen Predigten-Korpus
Authors: Pickl Simon 
Published: August 2019

AbstractDie Forschung zur Diachronie der Stellung des adnominalen Genitivs im Deutschen ist ein gutes Beispiel dafür, dass sich einzelne Fallstudien nur schwer zu einem schlüssigen Gesamtbild kombinieren lassen, wenn diese jeweils Zeitabschnitte mit unterschiedlichen Textsorten aus verschiedenen Regionen untersuchen. Durch uneinheitliche Quellenlage und Methodik wird die Vergleichbarkeit von Einzelstudien stark eingeschränkt. In diesem Beitrag wird ein alternativer Ansatz verfolgt, der auf einen zeitlichen Längsschnitt setzt. Indem sich der Fokus auf eine bestimmte Textsorte richtet, wird die annähernde Abdeckung der Zeit vom 9. bis zum 19. Jahrhundert auf einer gleichförmigen, wenn auch nicht repräsentativen Grundlage möglich. Als Textsorte wurden hier Predigten gewählt, da sich diese als Prosatexte gut für die Untersuchung syntaktischer Fragestellungen eignen und eine relativ lange, breite und kontinuierliche Überlieferung aufweisen. Neben der zeitlichen Entwicklung wird die Auswirkung verschiedener interner und externer Faktoren auf die Genitivstellung untersucht. In der Diskussion der Ergebnisse zeigt sich einerseits, dass der nachgestellte Genitiv durch seine größere syntaktische Flexibilität begünstigt wird; zum anderen wird deutlich, dass der Schwund des Genitivs im Gesprochenen nicht ohne Folge für seine Stellung blieb.
A Blind Medical Image Watermarking for Secure E-Healthcare Application Using Crypto-Watermarking System
Authors: Aparna Puvvadi , Kishore Polurie Venkata Vijay 
Published: August 2019

Abstract
A reliable medical image management must provide proper security for patient information. Protecting the medical information of the patients is a major concern in all hospitals. Digital watermarking is a procedure prevalently used to secure the confidentiality of medical information and maintain them, which upgrades patient health awareness. To protect the medical information, the robust and lossless patient medical information sharing system using crypto-watermarking method is proposed. The proposed system consists of two phases: (i) embedding and (ii) extraction. In this paper, we securely share three types of patient information, medical image, electronic health record (EHR), and face image from one hospital to another hospital. Initially, all the three inputs are encrypted and the information is concordant. In order to enhance the robustness of the crypto-watermarking system, the obtained bit stream is compressed, and the compressed bit streams are embedded into the cover image. The same process is repeated for the extraction process. The experimentation result is carried out using different medical images with EHR, and the effectiveness of the proposed algorithm is analyzed with the help of peak signal to noise ratio.
Does prosody meet syntax? A case study on standard Italian cleft sentences and left peripheral focus
Authors: Pinelli Maria Cristina , Poletto Cecilia , Avesani Cinzia 
Published: August 2019

AbstractIn this work we deal with two structures that have a very similar pragmatic function in Italian and have been claimed to have similar semantic and syntactic properties, namely clefts and left peripheral focus. Since Chomsky (1977. On wh-movement. In Peter W. Culicover, Thomas Wasow & Adrian Akmajian (eds.),Formal Syntax, 71–132. New York: Academic Press.) they have been both considered as instances of A’-movement and should therefore behave alike. Here we investigate their prosody and their syntax on the basis of three experimental studies and show that while the prosodic patterns found are indeed very similar, their syntax is less homogenous than expected if we apply general tests that have been traditionally used to distinguish A- from A’-movement. In particular, we will discuss three of these tests, namely parasitic gaps, weak crossover and anaphoric binding and show that the two constructions yield quite different results. We analyse the differences within the framework of featural relativized minimality originally proposed in Rizzi (2004. Locality and the left periphery. In Adriana Belletti (ed.),Structures and Beyond: The Cartography of Syntactic Structures 3, 223–251. Oxford: Oxford University Press.) and subsequent work. On this basis, we conclude that there is no one to one match between prosodic and syntactic properties, since we observe differences in the syntactic behaviour of the two constructions that do not surface in the prosodic patterns. Indirectly, this study sheds new light on the interface between prosody and syntax and is a confirmation of a modular theory of the components of grammar: some specific syntactic properties have no reflex in other components of grammar and can only be detected through purely syntactic tests.
Innovation aus Tradition
Authors: Ueberschaer Frank 
Published: August 2019

Zusammenfassung
Ps 103 ist ein Beispiel für die Adaption theologischer Traditionen für individuelle Frömmigkeit. Auf diese Weise gibt er zu erkennen, wie theologische Traditionen jenseits der textlichen Überlieferung tradiert und rezipiert wurden, und gewährt einen Einblick in die Verbindung und Komposition verschiedener Traditionen in einem einzelnen gedanklichen Zusammenhang.
A Note on the Significance of Quartic Autocatalysis Chemical Reaction on the Motion of Air Conveying Dust Particles
Authors: Animasaun I.L. , Koriko O.K. , Mahanthesh B. , Dogonchi A.S. 
Published: August 2019

Abstract
Little is known on the significance of fluid–particle interaction for velocity and temperature as in the case of centrifuge for separating particles of different types, launching of rockets, and motion of space shuttle through the air when there exist chemical reactions between the flow and the wall. The aim of this study is not only to explore the significance of quartic autocatalytic chemical reaction on the flow of dusty fluid in which the transmission of energy in form of electromagnetic is nonlinear but also to unravel the effects of buoyancy on the velocity of the dust and temperature of the dust. The nonlinear partial differential equations that model the transport phenomenon was transformed, nondimensionalised, and parameterised using suitable variables. The corresponding boundary value problems were converted to an initial value problem using the method of superposition and solved numerically. The outcome of the study indicates that enhancement of buoyancy is a yardstick to increase the vertical velocity, horizontal velocity, and shear stress within the fluid domain; increase the velocity of the dust particles; increase the temperature distribution across the flow of dusty fluid; increase the concentration of dusty fluid; and decrease the concentration of the catalyst. It is worth noticing that utmost velocity of the dust occurs at a minimum value of fluid–particle interaction for velocity in the flow over a larger thickness of paraboloid of revolution.
The new sodium tellurido manganates(II) Na2Mn2Te3, Na2Mn3Te4, Na2
AMnTe3 (A=K, Rb), and NaCsMnTe2
Authors: Langenmaier Michael , Röhr Caroline 
Published: August 2019

Abstract
A series of new sodium and mixed Na/A (A = K, Rb, Cs) tellurido manganates have been synthesized from melts of the pure elements (or MnTe) at maximum temperatures of 600–1000°C. The monoclinic crystal structures of the two pure sodium salts Na2Mn2Te3 (space group C2/c, a = 1653.68(2), b = 1482.57(2), c = 773.620(10) pm, β = 117.52°, Z = 8, R1 = 0.0225) and Na2Mn3Te4 (space group C2/m, a = 1701.99(3), b = 438.741(8), c = 691.226(12) pm, β = 90.3171(8)°, Z = 2, R1 = 0.0270) are both based on a hexagonal close packed Te2− arrangement. Na2Mn2Te3 is isotypic with Na2Mn2S3 and Na2Mn2Se3 and contains layers of [MnTe4] tetrahedra, which are connected via common edges to form tetramers [Mn4Te6]. These tetramers are further connected via μ
3-Te atoms. Na2Mn3Te4 crystallizes in a new structure type, recently also reported for the selenido salt Na2Mn3Se4. Mn(2) forms ribbons of vertex-sharing dinuclear units

∞
1

[

Te

2
/
2

MnTe

2

MnTe

2
/
2

]

$_\infty ^1[{\rm{T}}{{\rm{e}}_{2/2}}{\rm{MnT}}{{\rm{e}}_2}{\rm{MnT}}{{\rm{e}}_{2/2}}]$

running along the short b axis of the monoclinic cell. The Te atoms of these ribbons are also the ligands of edge-sharing [Mn(1)Te6] chains of octahedra. Similar to Na2Mn2Te3, the Na+ cations are octahedrally coordinated and the cations occupy tetrahedral (Mn2+) and octahedral (Na+, Mn2+) voids in the close Te2− packing. The isotypic K/Rb salts Na2
AMnTe3 crystallize in a new structure type (orthorhombic, space group Pmc21, a = 1069.70(4)/1064.34(2), b = 1350.24(5)/1350.47(3), c = 1238.82(4)/1236.94(3) pm, Z = 4, R1 = 0.0445/0.0210). In contrast to the simple formula indicating a Mn(III) compound, the complex structure contains one layer consisting of undulated chains of edge-sharing tetrahedra

∞
1

[

Mn

II

Te

4
/
2

]

$_\infty ^1[{\rm{M}}{{\rm{n}}^{{\rm{II}}}}{\rm{T}}{{\rm{e}}_{4/2}}]$

separated by free ditelluride dumbbells [Te2]2− and a second layer containing a complex chain of edge- and vertex-sharing [MnIITe4] tetrahedra, in which Mn(II) is coordinated to μ
1- and μ
2-Te2− ligands and an η
1-ditellurido ligand. The cesium salt NaCsMnTe2 (orthorhombic, space group Cccm, a = 694.21(2), b = 1536.57(4), c = 664.47(2) pm, Z = 4, R1 = 0.0131) likewise forms a new structure type, which is an ordered superstructure of ThCr2Si2. Linear chains

∞
1

[

MnTe

4
/
2

]

$_\infty ^1[{\rm{MnT}}{{\rm{e}}_{4/2}}]$

of edge-sharing tetrahedra are connected with similar chains

∞
1

[

NaTe

4
/
2

]

$_\infty ^1[{\rm{NaT}}{{\rm{e}}_{4/2}}]$

to form [NaMnTe2] layers. The larger alkali cations Cs+ between the layers exhibit a cubic (CN = 8) coordination.
Preparation and Physicochemical Characterization of Dual Responsive and Chemically Modified Cellulose Based Copolymer Hydrogels
Authors: Khan Abbas , Afzal Mehvish , Shah Luqman Ali , Zaman Khair , Khan Gul Shahzada , Badshah Amir 
Published: August 2019

Abstract
This research work is based on the preparation and physicochemical characterization of Poly(N-isopropylacrylamide)–Cellulose–Poly(Acrylic acid) [PNIPAAm–Cellulose–PAAc] based terpolymer hydrogels. The free radical polymerization reaction was initiated by the presence of ammonium persulphate (APS) and crosslinking between different monomers was occurring through N,Nl- Methylene bis-acrylamide (MBA). Confirmation of polymerization process was done by FT-IR and UV-visible spectroscopy. The prepared hydrogels were further characterized by different physicochemical techniques like rheology, Ostwald viscometry and dynamic light scattering (DLS). The effect of external stimuli like temperature, pH and composition of the samples on the physicochemical behavior was also carried out by dynamic rheology, swelling measurement and DLS. Various other properties like elasticity, shear stress, shear strain, loss modulus, storage modulus and complex viscosity was investigated by rheology. DLS was used to trace the size and swelling behavior of the samples. From the results obtained it was found that all the microgel samples are stimuli responsive and most of their physicochemical properties were prominently varying while changing the internal as well as the external experimental variable. These changes in physicochemical behavior of the gel can be attributed to two possibilities; the change in the hydrophobic character of gel (PNIPAAm) with temperature and also to the weakening of intermolecular hydrogen bonds with increase in temperature. As a result of this the PAA chains may undergo a transition from a compact conformation to an expanded coil conformation, resulting in the swelling of the hydrogels.