bluuebunny/crossref_metadata_2025_split huggingface dataset:
PI-QUAL version 2 image quality categorisation and inter-reader agreement compared to version 1
Authors: Lee Kang-Lung , Caglic Iztok , Liao Po-Hsiang , Kessler Dimitri A. , Guo Chao-Yu , Barrett Tristan 
Published: November 2024

Abstract
Objectives
Prostate imaging quality (PI-QUAL) was developed to standardise the evaluation of prostate MRI quality and has recently been updated to version 2. This study aims to assess inter-reader agreement for PI-QUAL v1 and v2 scores and investigates changes in MRI quality score categories.

Materials and methods
The study retrospectively analysed 350 multiparametric MRI (mpMRI) scans. Two expert uroradiologists independently assessed mpMRI quality using PI-QUAL v1 and v2 guidelines. Biparametric MRI (bpMRI) categorisation based on PI-QUAL v2 included only T2WI and diffusion-weighted imaging (DWI) results. Inter-reader agreement was determined using percentage agreement and kappa, and categorisation comparisons were made using the chi-square test.

Results
Substantial inter-reader agreement was observed for the overall PI-QUAL v1 score (κ = 0.64) and moderate agreement for v2 mpMRI (κ = 0.54) and v2 bpMRI scores (κ = 0.57). Inter-reader agreements on individual sequences were similar between v1 and v2 (kappa for individual sequences: T2WI, 0.46 and 0.49; DWI, 0.66 and 0.70; DCE, 0.71 and 0.61). Quality levels shifted from predominantly “optimal” in v1 (65%) down to “acceptable” using v2 (55%); p < 0.001. The addition of DCE increased the proportion of cases with at least “adequate” quality at mpMRI (64%) compared to bpMRI (30%); p < 0.001.

Conclusion
This study shows consistent inter-reader agreement between PI-QUAL v1 and v2, encompassing overall and individual sequence categorisation. A notable shift from “optimal” to “acceptable” quality was demonstrated when moving from v1 to v2, with DCE tending improving quality from “inadequate” (bpMRI) to “acceptable” (mpMRI).

Key Points
QuestionWhat are the agreement levels of image quality of prostate MRI by using PI-QUAL v1 and v2?
FindingsInter-reader agreement based on PI-QUAL v1 and v2 is comparable. Dynamic contrast enhancement (DCE) enables an overall shift from inadequate quality (at bpMRI) to acceptable quality (mpMRI).
Clinical relevanceThe inter-reader agreement on PI-QUAL v1 and v2 is equivalent. PI-QUAL v2 assesses prostate bpMRI as well as mpMRI quality. Transitioning from inadequate to acceptable between v2-bpMRI and v2-mpMRI highlights the role of DCE as an “image quality safety net.”
Defining a threshold for safe surgical management of vena cava thrombus in renal cell carcinoma patients: evidence from German total population data with 3,700 cases from 2006 to 2020
Authors: Martin Thomas , Huber Johannes , Koch Rainer , Butea-Bocu Marius , Haak Lennard , Flegar Luka , Giese Matthias , Kormann Fabian , Aksoy Cem , Zacharis Aristeidis , Groeben Christer 
Published: November 2024

Abstract
Purpose
The management of inferior vena cava (IVC) tumor thrombus in patients with renal cell carcinoma (RCC) is among the most challenging surgical procedures. We aimed to define a minimum annual caseload for sufficient expertise.

Methods
We identified all cases with RCC, nephrectomy, and IVC procedures in the Federal Statistical Office billing database (2006–2020). We defined annual hospital caseload categories as low (< 4 cases), medium (4–9 cases) and high (> 9 cases) volume. Logistic multivariate models identified mortality-related factors. In addition, we analyzed data on tumor stage distribution from German cancer registries.

Results
We recorded 3,700 nephrectomies with IVC-tumor resection with stable annual case number of 247 mean. This correlated with a stable incidence of T3b/c RCC. Patient age was 66 ± 14 years. Of all cases, 56% occurred in low, 30% in medium, and 14% in high volume clinics without a significant trend towards centralization. The overall in-hospital mortality rate was 5.8% and the transfusion rate 72%. An annual caseload of 8 showed to be a significant cut-off for mortality with 6.2% at < 8 cases and 2.8% for > = 8 cases annually (p < 0.001). Multivariate analysis revealed patient age (OR 6.4 for octogenerians) ventilation time (OR 14.3 for > 24 h) and hospital caseload (OR 2.6) as the most important risk factors for in-hospital mortality.

Conclusion
Our results show a negative correlation of annual caseload and mortality for this procedure. A minimum number of 8 procedures per year seems reasonable for the successful management of IVC tumor thrombus with significantly lower mortality.
Severe neonatal hyperbilirubinaemia in European and Indian subcontinent descendent newborns: a retrospective cohort study
Authors: Simões João Ferreira , Simão Margarida , Rocha Paula , Ferreira Sara , da Câmara Rosário Perry , Amaral Diana , Costa Beatriz , Coelho Mário 
Published: November 2024

Abstract
Neonatal hyperbilirubinaemia is more common in Asian-descendent populations, but differences in disease severity are poorly reported. Our study aimed to compare neonatal hyperbilirubinaemia severity between European and Indian subcontinent descendent newborns. We conducted a single-centre retrospective cohort study including newborns admitted with unconjugated hyperbilirubinaemia (January 2016 to December 2021). Patients were followed during admission, comparing those with European ancestry (control group) and Indian subcontinent ancestry (India, Pakistan, Bangladesh and Nepal) (study group). The primary outcome was severe hyperbilirubinemia (TSB > 25 mg/dL, phototherapy > 6 h or need for exchange transfusion [ET]), and the secondary was TSB levels. Adjusted analysis for potential confounding factors was performed using binary logistic regression models. Of 110 newborns included, 27 (24.5%) had Indian subcontinent ancestry. Occurrence of TSB > 25 mg/dL was significantly higher in the study group (22.2% vs. 4.8%, p = 0.006), while no differences were noted in exposure to phototherapy > 6 h and ET therapy. Logistic regression models for confounding factors adjustment showed Indian subcontinent ancestry as an independent risk factor for TSB > 25 mg/dL (OR 7.49, CI 95% [1.23–45.50]). The study group revealed also higher absolute values of TSB both at admission (22.0 mg/dL vs. 19.6 mg/dL, p = 0.013) and at discharge (13.6 mg/dL vs. 11.4 mg/dL, p = 0.005).

Conclusion: Our findings suggest that newborns with Indian subcontinent ancestry might show a higher risk for the development of severe hyperbilirubinemia compared to European ancestry newborns. Implementing earlier treatment thresholds in this subset of patients may help prevent severe hyperbilirubinemia.

What is Known:• Indian subcontinent descendent populations have high incidence of neonatal hyperbilirubinaemia but data regarding its severity are scarce.

What is New:• This article shows that, compared to European descendent newborns, Indian subcontinent descendent newborns might be at higher risk for severe hyperbilirubinaemia.
An Experimental Platform for Studying the Heteronuclear Efimov Effect with an Ultracold Mixture of $$^\textbf{6}$$Li and $$^\textbf{133}$$Cs Atoms
Authors: Lippi Eleonora , Gerken Manuel , Häfner Stephan , Repp Marc , Pires Rico , Rautenberg Michael , Krom Tobias , Kuhnle Eva D. , Tran Binh , Ulmanis Juris , Zhu Bing , Chomaz Lauriane , Weidemüller Matthias 
Published: November 2024

AbstractWe present the experimental apparatus enabling the observation of the heteronuclear Efimov effect in an optically trapped ultracold mixture of $$^6$$

6

Li-$$^{133}$$

133

Cs with high-resolution control of the interactions. A compact double-species Zeeman slower consisting of four interleaving helical coils allows for a fast-switching between two optimized configurations for either Li or Cs and provides an efficient sequential loading into their respective MOTs. By means of a bichromatic optical trapping scheme based on species-selective trapping we prepare mixtures down to 100 nK of $${1\times 10^{4}}$$

1
×

10
4

Cs atoms and $${7\times 10^{3}}$$

7
×

10
3

Li atoms. Highly stable magnetic fields allow high-resolution atom-loss spectroscopy and enable to resolve splitting in the loss feature of a few tens of milligauss. These features allowed for a detailed study of the Efimov effect.
Highly sensitive voltammetric determination of the fungicide fenhexamid using a cost-effective and disposable pencil graphite electrode
Authors: Erşan Teslime , Dilgin Didem Giray , Oral Ayhan , Skrzypek Sławomira , Brycht Mariola , Dilgin Yusuf 
Published: November 2024

Abstract A differential pulse voltammetric (DPV) method is proposed for the highly sensitive determination of fenhexamid (FHX) based on both electrooxidation and electroreduction processes using a disposable and cost-effective pencil graphite electrode (PGE). The electrochemical oxidation and reduction mechanisms of FHX at the PGE were elucidated by recording cyclic voltammograms at various pH values of Britton–Robinson buffer (BRB) solutions at a scan rate of 50 mV s−1 and different scan rate values in the range 10–400 mV s−1 at selected pH of BRB (pH 2.0). Differential pulse voltammograms recorded under optimized conditions revealed an oxidation peak of FHX around + 0.65 V and a reduction peak of FHX around + 0.45 V. The DPV analysis of FHX revealed two linear ranges: 0.001–0.01 µmol L−1 and 0.01–5.0 µmol L−1 for the anodic peak, and 0.001–0.1 µmol L−1 and 0.1–5.0 µmol L−1 for the cathodic peak. The limits of detection were 0.34 nmol L−1 and 0.32 nmol L−1 for the anodic and cathodic peaks, respectively. The proposed methodology demonstrated satisfactory selectivity, as selected pesticides, certain electroactive compounds, and cationic species tested did not interfere with the voltammetric determination of FHX, particularly during its reduction. The recovery results, showing values close to 100% obtained from the analysis of real samples spiked with FHX, indicated that this methodology can accurately determine FHX in water and soil samples.
Graphical abstract
Optimising landslide trigger analysis through integration of diverse dendrogeomorphic approaches and multi-source climate and documentary data
Authors: Tichavský Radek 
Published: November 2024

AbstractLandslides on forested slopes, which often lack extensive documentary data and monitoring, can be evaluated using tree-ring records. This method is commonly employed for assessing hydrometeorological triggers similar to sites with documentary-based landslide catalogues. However, uncertainties arise in setting dendrogeomorphic thresholds and using diverse climate data sources for trigger identification. This paper reconstructs the activity of six landslides using tree-ring records in a region with well-documented landsliding and long-term climate data from rain gauges. The objective was to test different dendrogeomorphic approaches for identifying landslide event year and to analyse various rain, snow, and soil moisture parameters from meteorological stations and climate reanalyses to identify triggers. This involved examining how variations in each research step affect results and potentially enhancing the interpretation of landslide triggers. Documentary data indicated frequent landsliding during spring and summer, while tree-ring chronologies showed the strongest connection to increased winter and spring precipitation measured by rain gauges, suggesting an enhancement of winter precipitation as a potential climate preparatory factor. Furthermore, the results showed that combining tree-ring and documentary data yielded more statistically informative links than using tree-ring data alone. Additionally, integrating gridded data from ERA5-Land climate reanalyses enhanced the interpretation of explanatory factors. While increased winter and spring precipitation were most strongly linked to landslide initiation using precipitation data, volumetric soil water content derived from reanalysis data was crucial for identifying summer landslide occurrences. Incorporating soil water content into dendrogeomorphic research improved the interpretation of landslide initiation timing. Therefore, regional tree-ring-based chronologies with improved identification of landslide triggers can significantly reduce uncertainties in decision-making when it comes to landslide hazard management. Future research should explore the effectiveness of freely available satellite-based precipitation data with tree-ring chronologies, particularly in regions with limited information on precipitation intensity.
ADHERE: a toolkit for retaining PWID living with hepatitis C in healthcare systems
Authors: Baptista-Leite Ricardo , Lopes Henrique , Franco Diogo , Hermenegildo Catarina , Clemens Timo , Brand Helmut 
Published: November 2024

Abstract
Aim
Despite advancements in hepatitis C care, significant gaps remain, particularly in retaining people who inject drugs (PWID) in treatment, which hinders progress toward achieving the World Health Organization’s (WHO) hepatitis C elimination goals. The ADHERE (Attract pwiD Hepatitis hEalthcaRE) toolkit was developed to address these challenges by optimizing linkage-to-care services for PWID, focusing on the critical steps within the care cascade (CC) where losses are most likely to occur.

Subject and methods
Retaining PWID through the entire treatment process until the achievement of sustained virologic response (SVR) remains a formidable challenge. The ADHERE toolkit interconnects micro-ecosystemic conditions with public health policy implementation, offering a structured approach to enhancing PWID retention in healthcare systems. This toolkit was developed through an extensive literature review and consultations with key opinion leaders (KOL) from seven countries, ensuring its relevance and applicability across diverse settings.

Results
The ADHERE toolkit provides a comprehensive framework and strategy for public health interventions, focusing on the later stages of the CC for hepatitis C. By facilitating continuous quality improvement and enabling the integration of various public health policies, the toolkit aims to minimize treatment dropouts and maximize the chances of achieving a cure among PWID.

Conclusion
The ADHERE toolkit aims to aid in advancing the management of hepatitis C among PWID, offering a feasible and auditable approach to improving patient retention and treatment outcomes. By establishing a robust network of health policy management processes, the toolkit is expected to contribute to the global effort to eliminate hepatitis C.
Introducing the legacies and trajectories of trauma to the archival field
Authors: Sexton Anna 
Published: November 2024

Abstract
Trauma as a concept, a signifier and a frame has become increasingly visible in archival theory and praxis in recent years. A shift that is perhaps unsurprising given that society at large appears to have embraced trauma as a major interpretative category for our age. The recent spotlight on trauma can also be linked to accompanying movements in our discourse as we have begun to unpack and theorise the affective dimensions of records work and have moved towards more person-centred approaches. While the recent introduction of trauma-informed approaches to our field is a welcome development in many ways, this article seeks to critically engage with the Western concept of trauma to expose its intellectual lineages and the social and moral economies that have shaped its emergence in different spheres; and highlight how archival studies discourse on trauma is shaped in relation to different branches of Western trauma discourse. This article argues that as archivists and records workers adopt the language of trauma from adjacent arenas as an explanatory and transformative frame, it is vital that we do so in possession of an understanding of trauma’s conceptual legacies and in conversation with broader affective, liberatory and reparative framings. The article is written in the spirit of becoming truly ‘trauma-informed’.
Using Graphical Representations to Develop Students’ Correspondence Relationships and Covariational Thinking in Pattern Generalizations in Primary School
Authors: Sterner Helén 
Published: November 2024

AbstractAlgebra in primary school requires students to engage in functional thinking, including recursive patterning, covariational thinking, and correspondence relationships. However, research suggests that teaching to develop functional thinking is challenging in lower grades, because it risks resulting in discussions solely centered around recursive patterning. This article reports on an intervention where possibilities and limitations were studied when students used different representations to develop functional thinking while working with pattern generalizations. Sixty-nine students in Grade 6 in four different classes worked with graphs and other representations to identify and justify pattern generalizations. The results showed that the graphical representation enabled students to visualize and justify correspondence relationships, thereby developing their functional thinking. Furthermore, the use of graphs helped the students justify their pattern generalizations and shift their conversations from recursive patterning to covariational thinking and correspondence relationships. Consequently, the results emphasize the importance of teacher awareness in developing students’ functional thinking.
Evaluation of the Acceptability and Feasibility of Stress Mitigation Education and Support Delivered via Telehealth for People After Road Traffic Musculoskeletal/Orthopedic Injury
Authors: Sim Alison , McNeilage Amy G. , Rebbeck Trudy , Sterling Michele , Nicholas Michael , Donovan Sarah , Giummarra Melita J. , Ashton-James Claire E. 
Published: November 2024

Abstract
Purpose
To evaluate the acceptability and feasibility of a consumer co-designed telehealth intervention which aimed to reduce claimant distress by providing pain management strategies, informational and social support to people who had made a compensation claim following road traffic musculoskeletal injury.

Methods
Eleven claimant participants who were at risk of a poor outcome completed the intervention in a one-on-one setting with the same clinician delivering the program across all sessions.They were interviewed about their experience (acceptability and feasibility including the use of telehealth). Clinicians who delivered the intervention also completed an anonymous feedback survey exploring their experiences delivering the intervention. Interviews were transcribed verbatim and thematic analysis was conducted.

Results
There were four themes which broadly related to the acceptability and feasibility of the intervention as well as the perceived benefits: (1) knowledge is power, (2) healing with social connection, (3) further along than I would have been, and (4) telehealth was acceptable and feasible.

Conclusion
The delivery of a co-designed telehealth-delivered stress mitigation intervention to support people with a road traffic musculoskeletal injury was feasible to deliver and acceptable to people who were at risk of a poor outcome. Further research to evaluate the efficacy of the intervention on outcomes such as pain, self-efficacy, and claims costs are needed.
Review Essay: Judith Butler, Who’s Afraid of Gender? (London: Allen Lane, 2024) pp 308
Authors: Sharpe Alex 
Published: November 2024

AbstractThis article is a review essay of Judith Butler’s latest book, Who’s Afraid of Gender? The book considers the anti-gender ideology movement and rising right-wing authoritarianism with which it is associated. In review considers the following key themes that Butler disusses: recognition of a contemporary crisis; the creation of a moral panic around gender; the complicity of ‘gender critical’ feminism in enabling anti-feminist totalitarian politics; the disingenuous figuration of ‘censorship’ as a weapon deployed by the forces of ‘gender ideology’; and the relationship of the phantom to colonialism and race.
An Economic Justification for Rignano's Inheritance Tax Proposal
Authors: Peterfreund Yotam , Strawczynski Michel 
Published: November 2024

AbstractFamilies are widely recognized as crucial agents in the transmission of wealth, contributing to the perpetuation of inequality and limiting mobility across income levels. To address the economic dynamics behind this phenomenon, classical economists have explored potential solutions through government tax-transfer systems. One such proposal, advanced by Eugenio Rignano, suggests imposing higher taxes on inheritances passed down through multiple generations within a family. To analyze this idea, a model is developed that incorporates both altruistic and accidental bequests, with altruistic bequests playing a crucial role in wealth transmission. The model considers the potential disincentives that inheritance taxation might create for savings intended for altruistic bequests, as well as the benefits of taxing accidental bequests. The novelty of the model lies in its characterization of optimal inheritance taxes when there is an interaction between parents' educational decisions for their children and the transmission of wealth. Simulations suggest that adopting Rignano's proposed tax scheme enhances social welfare compared to the commonly used proportional inheritance tax. These findings suggest that Rignano's tax scheme warrants further research and policy discussion.
Towards circular economy through innovation: the role of entrepreneurial orientation and human resource management
Authors: Castro-Lopez Adrian , Entrialgo Montserrat , Liao Ching T. , Santos-Vijande María Leticia 
Published: November 2024

AbstractThe development of the circular economy (CE) has become a strategic priority for the EU to achieve the UN’s Sustainable Development Goals. While the number of CE-based start-ups is burgeoning, established companies seem to be slower to adopt CE. Incorporating CE principles requires established firms to transform their business processes and activities from a linear to a circular approach, which often requires the introduction of significant and complementary technological and non-technological innovations, as well as significant investments that may hamper the firm’s overall performance. Thus, the disruptive nature of CE adoption may make established firms reluctant to embrace this process and underlines the need to identify its drivers and to clarify its potential benefits. Accordingly, we analyze the role of entrepreneurial orientation (EO) in promoting circular human resource management (CHRM), circular product innovation and circular manufacturing. This study is the first to define and measure CHRM and one of the few to apply the concept of EO in the context of CE. Using seemingly unrelated regressions (SUR), we find that EO promotes circular innovation directly and indirectly through CHRM. This factor represents a non-technological innovation which directly impacts on circular product innovation and circular manufacturing, whilst reinforcing the complementarity between non- technological and technological innovation. This research also addresses concerns about potential conflicts in achieving different types of CE performance simultaneously. By analyzing firm performance from a holistic perspective, our study confirms that CE implementation leads to environmental, market and social performance improvements together with the moderating role of technological turbulence.