bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful treatment of BCG‐related immune reconstitution inflammatory syndrome following ex vivo T‐cell–depleted haploidentical hematopoietic stem cell transplantation: A case report
Authors: Erbey Fatih , Dur Ayse Humeyra , Atay Didem , Akçay Arzu , Tecimer Tülay , Öztürk Gülyüz 
Published: May 2019

AbstractIRIS is a phenomenon describing localized inflammatory reactions at BCG vaccination site and development of lymphadenopathy as immune system recovers. It is a rare entity in children following haploidentical HSCT. We represent the successful treatment of a case with fluctuating lymphadenopathy due to BCG vaccine during immune reconstitution period following ex vivo T‐cell–depleted haploidentical HSCT.
Pediatric vascularized composite allotransplantation: What is the landscape for obtaining appropriate donors in the United States?
Authors: Mendenhall Shaun D. , Sawyer Justin D. , West Bradford L. , Neumeister Michael W. , Shaked Abraham , Levin Lawrence S. 
Published: May 2019

AbstractListing the world's first pediatric bilateral hand transplant patient for a donor posed many challenges including matching the appropriate donor age, bone size, skin tone, and growth potential in an already limited donor population. This study describes the prevalence and distribution of potential pediatric VCA donors in the United States. We assessed the UNOS database from 2008 to 2015 to identify the prevalence of potential pediatric VCA donors. Standard VCA inclusion and exclusion criteria were applied to the dataset for all pediatric solid organ donors. Frequency analyses were performed of characteristics important for VCA matching. The dataset began with 57 300 brain‐dead donors and after applying the inclusion and exclusion criteria including age <18, decreased to 4663 (8.1%). The number of pediatric potential VCA donors per UNOS region ranged from 11 to 112/year. The majority of pediatric potential VCA donors were blood type O Whites, with the least common profile being blood type AB of “other” ethnicity. The present study confirmed that pediatric VCA donors are rare and may require longer travel times for procurement and listing at multiple centers in order to find a suitable donor. This will be a limiting factor for the expansion of pediatric VCA.
Social Control Meets New Public Management: Examining the Diffusion of State Prison Privatization, 1979‐2010
Authors: Mitchell Joshua L. , Butz Adam M. 
Published: May 2019

While the merits and perils of privatization have remained a contentious and often polarizing debate, privatization of public services remains commonplace throughout the world. For instance, over the last several decades, U.S. governments at all levels have routinely pursued contracting arrangements for corrections management, known popularly as prison privatization. In this article, state prison privatization (SPP) is examined in three ways. First, we use an externally focused policy diffusion framework to help explain the adoption of SPP‐enabling legislation across U.S. states. Second, we explore the extent to which the American Legislative Exchange Council has influenced the adoption of prison privatization legislation. Third, we explore the role of state wealth inequality in determining a state's propensity to adopt prison privatization policies. Examining state‐level data from 1979 to 2010, this article finds empirical support for each of these key theoretical assertions. Furthermore, we find evidence that the external diffusion effect may vary depending on the political orientation of the state.Related ArticlesButz, Adam M., Michael P. Fix, and Joshua L. Mitchell. 2005. “Policy Learning and the Diffusion of Stand‐Your‐Ground Laws.”Politics & Policy43 (3): 347‐377.https://doi.org/10.1111/polp.12116Gerlach, John David, Laron K. Williams, and Colleen E. Forcina. 2013. “The Science‐Natural Resource Policy Relationship: How Aspects of Diffusion Theory Explain Data Selection for Making Biodiversity Management Decisions.”Politics & Policy41 (3): 326‐354.https://doi.org/10.1111/polp.12017Morris, John C. 2007. “Government and Market Pathologies of Privatization: The Case of Prison Privatization.”Politics & Policy35 (2): 318‐341.https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1747-1346.2007.00062.xRelated MediaAmerican Civil Liberties Union of Ohio. 2015. “Prisons for Profit: 18 Months in the Life of the Nation's First Prison Sold for Profit.”https://www.youtube.com/watch?v=YQcZzS7eqfYNow on PBS. 2008. “Prisons for Profit.”https://www.pbs.org/now/shows/419/video.htmlSullivan, Eileen. 2016. “PBS News Hour: Obama Administration Set to End Use of Private Prisons.”https://www.pbs.org/newshour/nation/obama-administration-end-use-private-prisons
Sociopsychological characteristics of late nonagenarians in Japan: the protocol of the Arakawa 95+ study
Authors: Niimura Hidehito , Eguchi Yoko , Kida Hisashi , Suzuki Kouta , Takayama Midori , Mimura Masaru 
Published: May 2019

AimThe aim of this study was to examine sociopsychological characteristics of the oldest old in Japan. We conducted a baseline survey of a community‐based cohort of persons aged 95 or older.MethodsParticipants were aged 95+ years and resided in Arakawa Ward in Tokyo on 1 January 2016. We mailed a questionnaire to these individuals to assess their physical, mental, and social status. Subsequently, if respondents agreed, we conducted in‐home interviews and examined their physical and cognitive function. Also, we mailed non‐respondents a simplified version of full questionnaire. Additionally, we examined the basic registered data of the study population and the status of their Long‐term Care Insurance. Data at baseline and 1‐year follow‐up were compared.ResultsWith regard to Long‐term Care Insurance, 423 residents aged 95+ years (78.0%) were on long‐term care level, 35 (6.5%) were on support level, and 84 (15.5%) did not require support. At the 1‐year follow‐up, 275 (50.7%) had the same care level, 107 (19.7%) required a greater level of care, and 131 had died (annual death rate: 24.2%). Compared to the simplified questionnaire group (n = 128) and the full questionnaire‐only group (n = 14), a higher proportion of respondents who had completed the full questionnaire and had in‐home interviews (n = 26) were men, lived only with a spouse, had higher activities of daily living, and reported more positive feelings and well‐being.ConclusionsIn the late nonagenarian population, the annual death rate was high, and care needs increased rapidly. However, some persons maintained the same care level or even showed improvement and successful ageing.
Forest cover and climate as potential drivers for dengue fever in Sumatra and Kalimantan 2006–2016: a spatiotemporal analysis
Authors: Husnina Zida , Clements Archie C. A. , Wangdi Kinley 
Published: May 2019

AbstractObjectivesTo describe and quantify spatiotemporal trends of dengue fever at district level in Sumatra and Kalimantan, Indonesia in relation to forest cover and climatic factors.MethodsA spatial ecological study design was used to analyse monthly surveillance data of notified dengue fever cases from January 2006 to December 2016 in the 154 districts of Sumatra and 56 districts of Kalimantan. A multivariate, zero‐inflated Poisson regression model was developed with a conditional autoregressive prior structure with posterior parameters estimated using Bayesian Markov chain Monte Carlo simulation with Gibbs sampling.ResultsThere were 230 745 cases in Sumatra and 132 186 cases in Kalimantan during the study period. In Sumatra, the risk of dengue fever decreased by 9% (95% credible interval [CrI] 8.5–9.5%) for a 1% increase in forest cover and by 12.2% (95% CrI 11.9–12.6%) for a 1% increase in relative humidity. In Kalimantan, dengue fever risk fell by 17.6% (95% CrI 17.1–18.1%) for a 1% increase in relative humidity and rose by 7.6% (95% CrI 6.9–8.4%) for a 1 °C increase in minimum temperature. There was no significant residual spatial clustering in Sumatra after accounting for climate and demographic variables. In Kalimantan, high residual risk areas were primarily centred in North and East of the island.ConclusionsDengue fever in Sumatra and Kalimantan was highly seasonal and associated with climate factors and deforestation. Incorporation of climate indicators into risk‐based surveillance might be warranted for dengue fever in Indonesia.
eHealth interventions to facilitate work participation: a scoping review protocol
Authors: Øyeflaten Irene , Johansen Thomas , Nielsen Claus Vinther , Johnsen Tone Langjordet , Tveito Torill Helene , Momsen Anne-Mette Hedeager 
Published: May 2019

Review question:The objective of this scoping review is to identify and synthesize existing literature on the different types of eHealth interventions used in workplaces and healthcare settings to facilitate work participation. The following questions will be examined: For which user groups, in which settings and by which stakeholders are eHealth interventions provided? Are eHealth interventions that are aimed at work participation theory-driven or based on empirical evidence?
Physical assessment skills in nursing curricula: a scoping review protocol
Authors: Morrell Sherry , Ralph Jody , Giannotti Natalie , Dayus Debbie , Dennison Susan , Bornais Judy 
Published: May 2019

Review objective:
This review seeks to establish the current state of knowledge regarding physical assessment skills taught in nursing programs globally. It aims to explore the literature on physical assessment skills taught in nursing curricula globally, skills used by nurses in practice, skills used by students, and core physical assessment skills that are important to teach nursing students.
Cerebral oxygenation and blood flow in term infants during postnatal transition: BabyLux project
Authors: De Carli Agnese , Andresen Björn , Giovannella Martina , Durduran Turgut , Contini Davide , Spinelli Lorenzo , Weigel Udo Michael , Passera Sofia , Pesenti Nicola , Mosca Fabio , Torricelli Alessandro , Fumagalli Monica , Greisen Gorm 
Published: May 2019

ObjectivesA new device that combines, for the first time, two photonic technologies (time-resolved near-infrared spectroscopy and diffuse correlation spectroscopy) was provided and tested within the BabyLux project. Aim was to validate the expected changes in cerebral oxygenation and blood flow.MethodsA pulse oximeter and the BabyLux device were held in place (right hand/wrist and frontoparietal region, respectively) for 10 min after birth in healthy term infants delivered by elective caesarean section. Pulse oximeter saturation (SpO2), cerebral tissue oxygen saturation (StO2) and blood flow index (BFI) were measured over time. Tissue oxygen extraction (TOE) and cerebral metabolic rate of oxygen index (CMRO2I) were calculated.ResultsThirty infants were enrolled in two centres. After validity check of data, 23% of infants were excluded from TOE and CMRO2I calculation due to missing data. As expected, SpO2 (estimate 3.05 %/min; 95% CI 2.78 to 3.31 %/min) and StO2 (estimate 3.95 %/min; 95% CI 3.63 to 4.27 %/min) increased in the first 10 min after birth, whereas BFI (estimate −2.84×10−9 cm2/s/min; 95% CI −2.50×10−9 to −3.24×10−9 cm2/s/min) and TOE (estimate −0.78 %/min; 95% CI −1.12 to –0.45 %/min) decreased. Surprisingly, CMRO2I decreased (estimate −7.94×10−8/min; 95% CI −6.26×10−8 to −9.62×10−8/min).ConclusionsBrain oxygenation and BFI during transition were successfully and simultaneously obtained by the BabyLux device; no adverse effects were recorded, and the BabyLux device did not limit the standard care. The preliminary results from clinical application of the BabyLux device are encouraging in terms of safety and feasibility; they are consistent with previous reports on brain oxygenation during transition, although the interpretation of the decreasing CMRO2I remains open.Trial registration numberNCT02815618.
β-Cell compensation concomitant with adaptive endoplasmic reticulum stress and β-cell neogenesis in a diet-induced type 2 diabetes model
Authors: Huang Hui , Yang Kaiyuan , Wang Rennian , Han Woo Hyun , Kuny Sharee , Zelmanovitz Paula Horn , Sauvé Yves , Chan Catherine B. 
Published: May 2019

Insulin-secreting pancreatic β-cells adapt to obesity-related insulin resistance via increases in insulin secretion and β-cell mass. Failed β-cell compensation predicts the onset of type 2 diabetes (T2D). However, the mechanisms of β-cell compensation are not fully understood. Our previous study reported changes in β-cell mass during the progression of T2D in the Nile rat (NR; Arvicanthis niloticus) fed standard chow. In the present study, we measured other β-cell adaptive responses, including glucose metabolism and β-cell insulin secretion in NRs at different ages, thus characterizing NR at 2 months as a model of β-cell compensation followed by decompensation at 6 months. We observed increased proinsulin secretion in the transition from compensation to decompensation, which is indicative of impaired insulin processing. Subsequently, we compared adaptive unfolded protein response in β-cells and demonstrated a positive role of endoplasmic reticulum (ER) chaperones in insulin secretion. In addition, the incidence of insulin-positive neogenic but not proliferative cells increased during the compensation phase, suggesting nonproliferative β-cell growth as a mechanism of β-cell mass adaptation. In contrast, decreased neogenesis and β-cell dedifferentiation were observed in β-cell dysfunction. Furthermore, the progression of T2D and pathophysiological changes of β-cells were prevented by increasing fibre content of the diet. Novelty Our study characterized a novel model for β-cell compensation with adaptive responses in cell function and mass. The temporal association of adaptive ER chaperones with blood insulin and glucose suggests upregulated chaperone capacity as an adaptive mechanism. β-Cell neogenesis but not proliferation contributes to β-cell mass adaptation.
A new occurrence of lazulite from the Main Central Thrust in Kumaun Himalaya, India: fluid inclusion, EPMA and Raman spectroscopy focusing on lazulite in a highly tectonized zone
Authors: Chauhan Dinesh S. , Sharma Rajesh , Rao D. R. 
Published: May 2019

Abstract

The present study reports and investigates ‘lazulite’ occurring in the vicinity of a highly tectonized zone of the Main Central Thrust (MCT) in the Himalaya. The azure blue lazulite, hosted in quartz veins, occurs in fractured Berinag quartzite, which forms the footwall of the MCT near Sobla village in NE Kumaun Himalaya, India. Lazulite was investigated using SEM-EDX, micro Raman spectroscopy, fluid inclusion microthermometry and electron probe microanalysis (EPMA). Lazulite contains inclusions of rutile and hematite and has Mg/(Mg+Fe) ratios of 0.86 to 0.90. The phosphorus in lazulite shows a negative trend with Mg+Al contents. This lazulite is an intermediate solid solution near the lazulite end-member with a cationic composition in the structural formula: Mg
0.81–0.89
Fe
0.10–0.13
Al
1.88–1.98
P
2.00–2.07
. Its composition in the lazulite–scorzalite stability field points to a higher temperature of its formation. Fluids trapped as inclusions in lazulite and the associated quartz are generally C–O–H fluid. The fluid inclusion isochors for lazulite, together with the temperature calculated for metamorphism of the equivalent structural level in the adjacent area suggest 500–600°C and 7.25 to 9.25 kbar, which match the peak metamorphic temperature–pressure derived elsewhere for the Higher Himalayan Crystallines. Moderately enriched
δ
D‰ values and H
2
O–CO
2
–low NaCl fluid suggest that water from a deep reservoir, more likely a metamorphic fluid, participated in lazulite formation. Classic sigmoidal fluid inclusions in lazulite reveal their development during MCT shearing, whereas the overpressured fluid inclusions suggest a post-lazulite uplift. The MCT lazulite is interpreted to have formed during Himalayan shearing and concurrent metamorphism. The present study also implies that this refractory mineral can sustain fluid inclusions within it against intense deformation conditions, such as in the MCT.
Northward range extension of Porcellanopagurus nihonkaiensis Takeda, 1985 (Decapoda, Anomura, Paguridae) in Japan
Authors: Ohtsuchi Naoya , Hayakawa Jun , Kawamura Tomohiko 
Published: May 2019

Abstract
For the first time the occurrence of Porcellanopagurus nihonkaiensis Takeda, 1985 is reported both from Sagami Bay and Otsuchi Bay. The use of an empty shell of a true limpet of the family Lottiidae Gray, 1840 by Porcellanopagurus sp. is herein also reported for the first time.
Redescription of Pseudanuretes chaetodontis Yamaguti, 1936 (Copepoda, Siphonostomatoida, Caligidae) and description of some of its developmental stages, with a discussion on sexually dimorphic features in the genus
Authors: Izawa Kunihiko 
Published: May 2019

Abstract
Pseudanuretes chaetodontis Yamaguti, 1936 is redescribed based on both sexes, from specimens recovered from the branchial lamellae of Chaetodontoplus septentrionalis (Temminck & Schlegel, 1844) (Pisces, Pomacanthidae) in Japan. In addition, both sexes of copepodid V are described, as well as the free-living phase composed of two naupliar stages and the infective copepodid I stage, all reared from eggs, for the first time. Sexually dimorphic features found in the adult are discussed and it is pointed out herein that P. parvulus (Wilson, 1913) was described based on a copepodid V female specimen by that original author. Both sexes of the copepodid V exhibit sexually dimorphic features of the male type, i.e., in the maxilliped and in leg 5.
A General Revision of the Chronology of the Tagisken North Burial Ground
Authors: Bonora Gian Luca 
Published: May 2019

Abstract
The burial ground of Tagisken North, characterised by seven monumental mausolea and other adjoining structures made of mud brick and rammed earth, was excavated and studied by members of the “Khorezm Expedition” (KhAEE) in the 60’s and dated to the beginning of the 1st millennium BC (9th-8th centuries BC). This cemetery boasts a significant amount of artefacts pertaining to the Late Andronovo period.
In light of new archaeological findings and recent chronological refinements, and thanks to improved scientific cooperation within the academic world, greater accuracy in determining the chronology of steppe cultures through abundant radiocarbon dating and better research standards, the time has now come for a general revision of the chronology of this burial ground.
The radiocarbon sequence for the Andronovo culture is notably a subject of heated debate, due to the wide range of absolute dating. The differences between the chronological frames of Central Asia proposed by Russian-Central Asian and foreign archaeologists are considerable. Calibrated dates have, of course, extended the traditional periodization leading to alternative “high” chronologies, i.e. 300-500 years earlier than the traditional chronologies based on cross-cultural analogies and formal comparisons. Steppe and Pre-Aral materials may now be unquestionably linked to artefacts from Middle Asia. In the best of circumstances, the latter may in turn be linked to historical chronologies established for the Ancient Near and Middle East.
In light of this evidence, this paper proposes that the northern part of the Tagisken plateau was used as a burial ground as far back as the mid-2nd millennium BC, if not earlier, and continued to be used as such until the 13th century BC.
Storage Practices in the Merv and Serakhs Oases of the Partho-Sasanian Period
Authors: Kaim Barbara 
Published: May 2019

Abstract
In antiquity the oasis of Merv in the Murghab delta formed a relatively homogenous cultural region. At least from the Bronze Age onwards, the oasis shared a similar history with the neighbouring oasis of Serakhs in the ancient Tedjen delta. This paper focuses on storage practices in these two regions, drawing on recent archaeological work in the area which has revealed the existence of an array of methods for the storage and the administration of resources both in private dwellings and in official buildings. For a fuller picture, earlier storage practices and storage systems in these regions and neighbouring areas are first discussed, including specifically the area of the province of Parthia.
The Patrimonial Project of Dzhankent
Authors: Arzhantseva Irina , Gorshenina Svetlana 
Published: May 2019

Abstract
The archaeological site of Dzhankent, in addition to its geographical position and the wealth of finds from there, occupies a special place for several other reasons, too. It was the first site in Central Asia to be excavated (1740-1741) and photographed (1858), and it has recently become one of the national symbols of independent Kazakhstan (since 1991). Over the period of more than 270 years during which it has been studied, Dzhankent has been approached by generations of explorers, excavators and researchers from different theoretical positions and with different aims which have corresponded more or less to political or geopolitical programmes. The aim of this contribution is, on the one hand, to show how the various actors who worked at this site related to one another and to the various types of power (local, Tsarist, Soviet), and on the other hand, to analyze the changes in the theoretical approaches of these actors. At the same time, it is important to trace the transformation of Dzhankent, in its pre-colonial, colonial and post-colonial contexts, into a memorial supposedly linked to imperial or national identities which, in turn, had been forged around a constructed past.
Preparing for Brexit: Substance, Politics and Readiness in an International Re-negotiation
Authors: Darbishire Owen 
Published: May 2019

Abstract
The UK ‘Brexit referendum’ set in motion a unique and highly complex set of negotiations to withdraw from a fundamentally embedded economic and political union. The final referendum was preceded by a nine-month pre-negotiation phase; this article examines the dynamics of that stage. The context of a unilaterally initiated negotiation, together with the economic and political costs associated with it, distinguish it from the existing literature. Three analytical approaches are combined and built upon in this article: the tasks of the pre-negotiation phase, the readiness of the temporal moment, and the demands of multi-level, multi-party negotiations. The concept of psychological readiness has broad theoretical import, though explicit recognition is given that negotiators are not unitary decision makers and that the incorporation of a political analysis is required. The combination of these frameworks provides insight into the dynamics of this phase and the difficulties experienced by both the UK and EU27.
The Pre-negotiation of UN Human Rights Treaties: The Case of the Convention on the Rights of Persons with Disabilities
Authors: Herro Annie 
Published: May 2019

Abstract
Since 1965, nine UN human rights treaties have been adopted. Surprisingly, we know little about the conditions under which states arrived at the negotiation table because there has been no serious attempt to empirically identify the unique attributes of pre-negotiation in this context. This article examines the pre-negotiation of the UN Convention on the Rights of Persons (CRPD), drawing on diverse qualitative data sources such as interviews with state and non-state participants. Informed by a constructivist perspective, this study identifies esteem-seeking behavior as a key motivation for some states to negotiate. The article also shows how a transnational advocacy network influenced the pre-negotiation process by leveraging states’ esteem-seeking ambitions and appealing to their reputation as a way of pushing parties to negotiate. Additional tactics that the transnational advocacy network employ at the international level to expedite negotiations are also identified.