bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extroversão do patrimônio arqueológico salvaguardado: reserva técnica do laboratório de arqueologia Peter Hilbert
Authors: Pereira Daiane 
Published: February 2018

A limitação dos processos de extroversão das informações e dos bens arqueológicos é uma realidade corrente. Isso mantém as coleções maciçamente armazenadas, enquanto uma pequena parcela participa de exposições e ações educativas. Tendo como objeto de estudo a reserva técnica do Laboratório de Arqueologia Peter Hilbert, vinculada ao Instituto de Pesquisas Científicas e Tecnológicas do Estado do Amapá, a presente pesquisa analisa mecanismos conceituais e práticos que podem contribuir para a potencialização da reserva técnica desse núcleo de pesquisa em espaço de extroversão das informações e do patrimônio arqueológico. Ao problematizar as possibilidades e os desafios atuais da gestão das coleções arqueológicas salvaguardadas em reservas técnicas, abordo aspectos da cadeia operatória da museologia e da cadeia produtiva da arqueologia, utilizando como arcabouço teórico a relação interdisciplinar entre a arqueologia e a museologia, relativa ao processo de musealização do patrimônio arqueológico.
PREVALENCE OF HUMAN PAPILLOMAVIRUS GENOTYPES IN LOW AND HIGH GRADE SQUAMOUS INTRAEPITHELIAL LESIONS AT CERVICAL TISSUE
Authors: Prasetyo Rizki Eko , Mastutik Gondo , Mustokoweni Sjahjenny 
Published: February 2018

HPV infection is known to cause cervical cancer. This study aimed to identify the variant of HPV genotypes of cervical precancerous lesions from low grade squamous intraepithelial lesion (LSIL) and high grade squamous intraepithelial lesion (HSIL). This was an explorative study using formalin fix paraffin embedded (FFPE) from cervical precancerous lesions at Dr. Soetomo Hospital, Surabaya. DNA was extracted from FFPE and hybridized for HPV genotyping using Ampliquality HPV Type Express kit (AB ANALITICA) by reverse line blot techniques. The results showed that there were variants of HPV genotype in LSIL. The variants were HPV16 (8/15), HPV18 (3/15), HPV52 (1/15), HPV6+31 (1/15), HPV6+18 (1/15), and HPV72+68 (1/15), and in HSIL which were HPV16 (4/10), HPV18 (2/10), HPV59 (1/10), HPV6+45 (1/10), HPV61+26 (1/10), and HPV16+31 (1/10). The characteristics of infection in LSIL were single infection of high-risk (hr) HPV and multiple infection of low-risk (lr)+hr HPV, and in HSIL were single infection of HPVhr, multiple infection of HPVhr+hr and HPVlr+hr. In conclusion, HPV prevalence in cervical precancerous lesions is single infection by HPV16 (48%), HPV18 (20%), HPV52 (4%), HPV59 (4%), and multiple infection by HPV6+31, HPV6+18, HPV6+45, HPV16+31, HPV61+26, HPV72+68 is 4%.
Team Approach: Preventing Surgical Site Infections in Pediatric Scoliosis Surgery
Authors: Mackenzie W.G. Stuart , McLeod Lisa , Wang Kevin , Crotty Jennifer , Hope Jennifer E. , Imahiyerobo Thomas A. , Ko Riva R. , Anderson Richard C.E. , Saiman Lisa , Vitale Michael G. 
Published: February 2018

* While some segments of the population of patients undergoing pediatric spine surgery are at considerable risk for infection, standardized processes and the involvement of a dedicated team can serve to minimize this risk.* A well-functioning perioperative team is a necessary prerequisite for the promotion of a culture focused on patient safety and the quality of care.* The use of Comprehensive Unit-based Safety Program principles is a powerful and well-tried way to foster team development, facilitate best-in-practice processes, and improve culture.* Organizations that wish to excel in the care of patients with complex pediatric spine deformity should invest heavily in the development of multidisciplinary dedicated teams, an investment that not only is an ethical prerequisite for the care of this fragile population but also is an effort that will deliver considerable returns following implementation.* The goal of the present review is to demonstrate how the use of a multidisciplinary team approach can be used to optimize and innovate regarding the prevention of surgical site infections in patients with pediatric scoliosis.
MODEL SIMULASI PERKEMBANGAN, PERTUMBUHAN DAN NERACA AIR TANAMAN KENTANG PADA DATARAN TINGGI DI INDONESIA
Authors: Salwati NFN 
Published: February 2018

<div data-canvas-width="788.5249999999997">This research aims to construct a simulation model of development, growth and waterbalance of potato crop. Reasearch</div><div data-canvas-width="802.7183333333334">also predicts climate change impact on potato productivity in several potato production center in Indonesia. The crop</div><div data-canvas-width="802.6816666666664">model being constructed explains process mechanism of development and growth during crop life cycle as a response</div><div data-canvas-width="802.7166666666672">to fluctuation of climatic. Three field experiments were conducted at three locations at Pacet and Galudra in West Java</div><div data-canvas-width="802.7066666666665">Province, and at Kerinci in Jambi Province, to support the model development; for model calibration (Pacet) and model</div><div data-canvas-width="802.6899999999999">validation (Galudra and Kerinci). Paired t-test between model predictions of Granola variety with observations showed</div><div data-canvas-width="802.7116666666665">that there were not significant differences (P&gt; 0,05) on all variables tested, except leaf biomass. In Atlantic variety, there</div><div data-canvas-width="802.6650000000001">were not significant differences (P&gt; 0,05) on root, tuber biomass and soil water content. Based on graphical test showed</div><div data-canvas-width="244.87999999999997">coefficient of determination were (R</div><div>2</div><div data-canvas-width="552.9633333333334">) greater than 0,80 for all variables.Generally, results on validation suggested that</div><div data-canvas-width="802.6866666666666">model predictions were not significantly different with field measurements at Galudra (Granola variety) and Kerinci</div><div data-canvas-width="802.6966666666668">(Atlantis and Granola variety) for variable of plant ages, biomass of root, stem, leaf and tuber, leaf area index, and soil</div><div data-canvas-width="98.58333333333331">water content. </div>
KERAGAMAN MORFOLOGI DAN GENETIK LENGKENG DI JAWA TENGAH DAN JAWA TIMUR
Authors: Mariana Baiq Dina , Sugiyatno A. 
Published: February 2018

<div id="__zsc_once"> <div style="left: 85.0393px; top: 628.955px; font-size: 16.6667px; font-family: serif; transform: scaleX(1.00069);" data-canvas-width="230.73333333333335">Tujuan penelitian keragaman lengkeng di Jawa Tengah dan Jawa Timur untuk memperoleh informasi keragaman morfologi dan genetik lengkeng yang berkembang di daerah Jawa Tengah dan Jawa Timur beserta keunggulannya masing-masing. Keragaman diamati dari 35 aksesi hasil eksplorasi di dua daerah tersebut. Hasil analisa DNA menggunakan penanda RAPD menunjukkan ke 32 aksesi tersebut memiliki tingkat kesamaan antara 36-96% yang terbagi kedalam empat kelompok besar pada tingkat kemiripan 40%. Kelompok pertama dengan tingkat kemiripan berkisar antara 42%-73% terdiri atas 16 aksesi, kelompok kedua dengan tingkat kemiripan 52% terdiri atas dua aksesi, kelompok ketiga dengan tingkat kemiripan antara 64%-96% terdiri atas 9 aksesi dan kelompok ketiga dengan tingkat kemiripan 73%-91% yang terdiri atas 5 aksesi. Aksesi yang memiliki kekerabatan terdekat adalah Tawangmangu 1 dan Tawangmangu 2 dengan tingkat kemiripan 96%, sedangkan aksesi dengan tingkat kekerabatan terjauh adalah Bandungan 1 dengan Purworejo 3. Dari 35 aksesi tersebut, diperoleh empat aksesi yang memiliki kualitas buah yang unggul, yaitu Pingpong, Tanpa Nama, Lokal Batu dan Itoh.</div></div><div id="__if72ru4sdfsdfruh7fewui_once" style="display: none;"> </div><div id="__hggasdgjhsagd_once" style="display: none;"> </div>
Characteristic of Analog Rice Using Hot Extruder Twin Screw
Authors: Diniyah Nurud , Puspitasari Amelia , Nafi Ahmad , Subagio Achmad 
Published: February 2018

<p>The research aimed to determine the characterization of the physical, chemical and organoleptic of analog rice. Samples from analog rice consist two formulations e.i with 50% <em>mocaf</em> 50% corn flour (R) and with propotion 40% <em>mocaf</em> : 50% corn flour: 10% sweet potato (U), triplicated. Parameters lightness, Hue, weighs of 100 grain, weight per grain, bulk density, proximat and organoleptics were analysed. Beras analog R and U have characteristic values of L (Lightness) 33.2-37.0 and Hue (ºH) 96.0-360.9, weighs of 100 grain 3.12-3.52 grams and weight per grain 0.031-0.035 grams, bulk density 0.617-0.639 g/ml, moisture content 11.50-13.73%, ash content 0.69-0.97%, protein 4.22-7.67%, crude fat 0.716-0.725%, carbohydrate 76.90-82.86%, starch 65.39-74.79%, amylose 4.76-4.82%, amylopectin 95.18-95.24% and in vitro digestibility 49.45-51.18%.</p><p> </p><p><strong>KARAKTERISTIK BERAS ANALOG MENGGUNAKAN <em>HOT EXTRUDER TWIN SCREW</em></strong></p><p>Tujuan penelitian ini adalah untuk mempelajari sifat fisik, kimia dan organoleptik dari beras analog berbahan dasar <em>mocaf</em>, tepung jagung dan ubi ungu. Sampel yang digunakan terdiri dari 2 formulasi beras analog menggunakan <em>mocaf</em> 50% : tepung jagung 50% (R) dan <em>mocaf</em> 40% : tepung jagung 50% : tepung ubi ungu 10% (U) yang diulang sebanyak 3 kali dengan parameter yang diuji meliputi kecerahan (L*), Hue (ºH), bobot 100 butir, berat per butir, densitas kamba, proksimat dan organoleptik. Beras analog R dan U memiliki karakteristik yaitu 33,2-37,0 (nilai kecerahan); 96,0-360,9 Hue (ºH); 3,12-3,52 gram (bobot 100 butir); 0,031-0,035 gram (berat per butir); 0,617-0,639 gram/mL (densitas kamba); 11,50-13,73% (kadar air); 0,69-0,97% (kadar abu); 4,22-7,67% (kadar protein); 0,716-0,725% (kadar lemak); 76,90-82,86% (kadar karbohidrat); 65,39-74,79% (kadar pati); 4,76-4,82% (kadar amilosa); 95,18-95,24% kadar amilopektin dan 49,45-51,18% (daya cerna).</p>
A Regularized Production-Optimization Method for Improved Reservoir Management
Authors: Fu Jianlin , Wen Xian-Huan 
Published: February 2018

Summary
Model-based production optimization has become a promising technique in recent years for improving reservoir management and asset development in the petroleum industry. A variety of methods have been developed to address production-optimization problems. However, many solutions resulting from these methods are not ready to be accepted by (operations) engineers because they are difficult to understand and implement in practice. A typical example is the erratically oscillatory, bang-bang-type solution of well-control optimization problems. For this challenge, a regularized optimization problem is formulated in this work with two purposes: to create smooth solutions and to improve the convergence speed. Furthermore, the original, high-dimensional optimization problems can be reduced to low-dimensional ones by a principal-component-analysis (PCA) -based regularization method such that some population-based methods, including genetic algorithm (GA) and particle-swarm optimization (PSO), can be used as search engines to find optimal or improved solutions that tend to have less chance of trapping in local optima. Examples show that the methodology proposed can ensure a continuous transition over time between variables (e.g., well controls) such that the generated solution is more acceptable to the (operations) engineers. Moreover, it significantly speeds up the convergence of the optimization process, allowing large-scale problems to be addressed efficiently.
A construct of the instrument for measuring junior high school mathematics teacher's self-efficacy
Authors: Widdiharto Rachmadi , Kartowagiran Badrun , Sugiman Sugiman 
Published: February 2018

The aim of this study was to develop a construct of the instrument for junior high school mathematics teacher self-efficacy and its mapping in the Special Region of Yogyakarta. The population was 816 junior high mathematics teacher and a sample of 274 teachers was selected through proportionate random sampling technique. The data were analyzed using Confirmatory Factor Analysis (CFA), using software Lisrel 8.80 through the first order and the second order stages. The result of data analysis toward four dimensions obtained: 11 fit items for dimension of personal efficacy (PE), 12 fit items for dimension of general teaching efficacy (GTE), 13 fit items for dimension of subject matter teaching efficacy (STE), and 8 fit items for dimension of outcome efficacy (OE). Afterward, the result of selecting 54 items in the first order stage was examined for the second order CFA which obtained Chi-Square = 297.58; df = 271; p-value = 0.12824; RMSEA = 0.019, which showed the model was fit to the data and obtained 25 fit items. The loading factors for each dimension PE, GTE, STE, and OE consecutively were: 0.46; 0.84; 0.89, and 0.92, and mapping of mathematics teacher self-efficacy level, which showed: 43.07% in low category, 55.47% in medium category (55.47%) and 1.46% in the high category.
Determination of Dog Gelatins Based on Amino Acid Profils and Chemometrics
Authors: Rahayu Wiranti Sri , Rohman Abdul , Martono Sudibyo 
Published: February 2018

Gelatin is a protein obtained by bolling skin, tendons, ligament, and bones with water. Gelatin is widely use in some food products and pharmaceutical industry. Some religions like Islam prohibited their followers to consume any food products containing pig and dog derivates, incluiding gelatin. The detection of some forbidden content in food product has been an important subect of stuydy in many countries. The current study was aimed to differentiate of dog gelatin from goat, bovine and porcine based on their amino acid profiles combined with chemometric of principal component analysis (PCA). Separation and determination of amino acid using liquid chromatography mass spechtroscopy. The results show that the fifth most amino acid content in dog gelatin were glutamic acid, glicine, alanine, arginine and methionin .Parameters of peak heihgt percentage of each amino acids from each samples were analyzed by PCA. Based on PC1 and PC2, gelatin from dog, goat, bovine and porcine could be distinguished.
PENGARUH PERSEPSI GURU SMP TERHADAP MINAT MEMANFAATKAN INTERNET SEBAGAI SUMBER BELAJAR
Authors: Sri Harjanto Elistya Rimawati, 
Published: February 2018

This study is aimed at measuring the teachers’ interest in using internet as the source of study related with the variables perception of information technology, easiness, and risk. The measurement of the variables’ influence is conducted to find out the teachers’ readiness in using internet in their teaching. The samples of the study are the teachers of either public or private junior high schools in Surakarta residence. The data used in this study is the primary data gained by distributing questionaires randomly. The result of the analysis is that the technology perception positively influences the teachers’ interest in using internet as the source of study as much as 0.441 while the easiness perception does the same thing as much as 0.465. On the other hand, the risk perception contributes negative influence of 0.117. The junior high school teachers’ decision to use internet as the source of study is 51.3% influenced by the preception of information technology, the easiness perception, and the risk perception while 48.7% is influenced by other factors excluded in this study. The results of this study can be used as a basis for policy making resource development of teachers.Keywords: information technology, easiness, rick, interest
Stabilized Low-n Amyloid-β Oligomers Induce Robust Novel Object Recognition Deficits Associated with Inflammatory, Synaptic, and GABAergic Dysfunction in the Rat
Authors: Watremez William , Jackson Joshua , Almari Bushra , McLean Samantha L. , Grayson Ben , Neill Joanna C. , Fischer Nicolas , Allouche Ahmad , Koziel Violette , Pillot Thierry , Harte Michael K. 
Published: February 2018

Background: With current treatments for Alzheimer’s disease (AD) only providing temporary symptomatic benefits, disease modifying drugs are urgently required. This approach relies on improved understanding of the early pathophysiology of AD. A new hypothesis has emerged, in which early memory loss is considered a synapse failure caused by soluble amyloid-β oligomers (Aβo). These small soluble Aβo, which precede the formation of larger fibrillar assemblies, may be the main cause of early AD pathologies. Objective: The aim of the current study was to investigate the effect of acute administration of stabilized low-n amyloid-β1-42 oligomers (Aβo1-42) on cognitive, inflammatory, synaptic, and neuronal markers in the rat. Methods: Female and male Lister Hooded rats received acute intracerebroventricular (ICV) administration of either vehicle or 5 nmol of Aβo1-42 (10 μL). Cognition was assessed in the novel object recognition (NOR) paradigm at different time points. Levels of inflammatory (IL-1β, IL-6, TNF-α), synaptic (PSD-95, SNAP-25), and neuronal (n-acetylaspartate, parvalbumin-positive cells) markers were investigated in different brain regions (prefrontal and frontal cortex, striatum, dorsal and ventral hippocampus). Results: Acute ICV administration of Aβo1-42 induced robust and enduring NOR deficits. These deficits were reversed by acute administration of donepezil and rolipram but not risperidone. Postmortem analysis revealed an increase in inflammatory markers, a decrease in synaptic markers and parvalbumin containing interneurons in the frontal cortex, with no evidence of widespread neuronal loss. Conclusion: Taken together the results suggest that acute administration of soluble low-n Aβo may be a useful model to study the early mechanisms involved in AD and provide us with a platform for testing novel therapeutic approaches that target the early underlying synaptic pathology.
Utility of the LIBRA Index in Relation to Cognitive Functioning in a Clinical Health Seeking Sample
Authors: Pons Anke , LaMonica Haley M. , Mowszowski Loren , Köhler Sebastian , Deckers Kay , Naismith Sharon L. 
Published: February 2018

Background: Dementia prevalence is expected to increase substantially over the next few decades. Since there is currently no cure for dementia available, there is an urgent need for the early identification of individuals at high risk for dementia, so that primary and secondary prevention strategies can be implemented. Recently, the LIfestyle for BRAin health (LIBRA) index was developed as a new dementia risk algorithm. It specifically focuses on modifiable risk and protective factors that can be targeted in midlife. Objective: The objective of this study was to evaluate the LIBRA index in relation to markers of cognitive functioning in a clinical, health-seeking sample of community-based older adults. Methods: 484 participants (mean age 62.7 years) were recruited from the Healthy Brain Ageing Clinic at the Brain and Mind Centre, Sydney. Participants underwent comprehensive clinical and neuropsychological assessment and completed a self-report survey pack. Participants were rated via consensus as having either subjective cognitive complaints (SCC) or meeting criteria for mild cognitive impairment (MCI). The LIBRA score was calculated based on 11 available risk and protective factors. Results: 65.4% of the sample met criteria for MCI. People with MCI showed a significantly higher LIBRA score compared to people with SCC. Furthermore, multiple cognitive domains, in particular executive functioning, were associated with a higher LIBRA score, with stronger correlations in people with MCI. Conclusion: The LIBRA index might be a useful tool to determine lifestyle-attributable risk of cognitive decline in an older health-seeking population, including people with MCI.
Circulatory Levels of Toxic Metals (Aluminum, Cadmium, Mercury, Lead) in Patients with Alzheimer’s Disease: A Quantitative Meta-Analysis and Systematic Review
Authors: Xu Lin , Zhang Wenchao , Liu Xianchen , Zhang Cuili , Wang Pin , Zhao Xiulan 
Published: February 2018

Background: Environmental exposure to toxic metals has been postulated to play a role in the pathophysiological processes of Alzheimer’s disease (AD). However, the circulatory levels of toxic metals in AD patients are not consistent in previous studies. Objective: To systematically assess levels of toxic metals (aluminum, mercury, cadmium, lead) in the circulation (blood, serum/plasma) of AD patients and controls. Methods: PubMed, Web of Science, Science Direct, Cochrane Library, and the China National Knowledge Infrastructure (CNKI) were systematically searched to identify studies published up to January 1, 2017. Meta-analyses were performed using random-effects models and the pooled standardized mean difference (SMD) were reported with 95% confidence intervals (CI). Results: We identified 17, 7, 8, and 10 studies for aluminum, mercury, cadmium, and lead, respectively. Meta-analyses showed significantly elevated circulatory levels of aluminum (SMD = 1.08, 95% CI: 0.66, 1.50), mercury (SMD = 0.55, 95% CI, 0.15, 0.95), and cadmium (SMD = 0.62, 95% CI: 0.12, 1.11), whereas lower levels of lead (SMD = –0.23, 95% CI: –0.38, –0.07) in AD patients than in controls. Publication bias was only observed for aluminum studies, but the “trim and fill” analysis showed that the publication bias did not alter the direction of the effect. Sensitivity analyses showed no studies from the pooled analysis changed the results. Conclusion: Compared to controls, circulatory levels of aluminum, mercury, and cadmium are significantly higher but the levels of lead were reduced in AD patients. These findings suggest that elevated aluminum, mercury, and cadmium in the circulation, especially in serum may play a role in the progression of AD.
Relationship of Area of Soft Drusen in Retina with Cerebral Amyloid-β Accumulation and Blood Amyloid-β Level in the Elderly
Authors: Shoda Chiho , Kitagawa Yorihisa , Shimada Hiroyuki , Yuzawa Mitsuko , Tateno Amane , Okubo Yoshiro 
Published: February 2018

Background: Histopathological studies have confirmed that soft drusen contains amyloid-β (Aβ). Objective: To examine the relationship between the area of soft drusen in the macular area and cerebral Aβ accumulation or plasma Aβ level in elderly persons without dementia. Methods: Fourteen consecutive patients (18 eyes) aged ≥50 years with macular soft drusen were studied prospectively. From color fundus photographs, the area of soft drusen (pixel) within a 6,000 μm diameter with the macula as center was measured. Standard uptake value ratio (SUVR) was obtained from positron emission tomography using florbetapir, which indicates the ratio of cerebral cortical-to-cerebellar Aβ accumulation. Ratio of plasma Aβ1-42 to Aβ1-40 level was calculated. Results: Mean age was 73.3±7.6 years. The soft drusen area was 4.32±2.42 mm2. The SUVR was 1.08±0.15. Plasma Aβ1-42/Aβ1-40 ratio was 0.17±0.08. When SUVR ≥1.10 was defined as positive and <1.10 as negative, the soft drusen area in SUVR-positive patients (6.19±1.14 mm2) was significantly ( p = 0.0043) larger than that in SUVR-negative patients (3.13±2.27 mm2). Multivariate regression analysis showed that SUVR positivity correlated with soft drusen area ( p = 0.0484) and with Voxel-based Specific Regional Analysis System for Alzheimer’s Disease score ( p = 0.0360). However, there was no correlation with gender ( p = 0.1921), age ( p = 0.2361), Alzheimer’s Disease Assessment Scale score ( p = 0.6310), Mini-Mental State Examination score ( p = 0.4246), or plasma Aβ1-42/Aβ1-40 ratio ( p = 0.8398). Conclusion: Among elderly persons without dementia, the area of soft drusen was larger in those with more extensive cerebral Aβ accumulation. The area of soft drusen may be a biomarker of cerebral Aβ accumulation.