bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE GENDERED IMPACT OF COVID-19: HOW INDONESIAN WOMEN ARE DISPROPORTIONATELY AFFECTED
Authors: Anabel Iva , Kusumasari Bevaola 
Published: November 2024

Gender is not the forefront issue of the COVID-19 pandemic yet lessons from previous outbreaks have suggested that women are disproportionately affected during such crises. This paper aims to understand the gendered impacts of the pandemic in Indonesia and offer insights into the experiences of women during the pandemic. We collected 10 administrative and survey data from government agencies, international organizations, as well as private organizations to conduct a secondary data analysis on the gendered impact of COVID-19 in Indonesia. Women are found to be bearing the brunt during the COVID-19 pandemic namely employment disruption, the burden of unpaid domestic and care work, heightened risk of gender-based violence, as well as indirect health and wellbeing impacts which includes accessibility to sexual and reproductive health services and stress levels.
Can KOOS-PS be replaced with a simple anchor question in patients after total knee arthroplasty?: an agreement study of 2,478 primary surgeries
Authors: Bjørgen Winther Siri , Sjøstrøm Anders , Liabakk-Selli Sølvi , Foss Olav A , Wik Tina S , Klaksvik Jomar 
Published: November 2024

Background and purpose: Physical function and pain are the most important outcomes following total knee arthroplasty (TKA). These can be evaluated by patient-reported outcome measures (PROMs), or by an anchor question. The primary aim of the study was to evaluate whether a simple anchor question can replace KOOS-PS in assessing postoperative knee function until 1-year follow-up, evaluated by analyzing the agreement between the 2 methods using the diagnostic odds ratio (DOR). Secondary aims were pain (NRS) at rest and during mobilization.Methods: This is a diagnostic accuracy study with primary TKAs performed between 2010 and 2022. The surgeries were categorized as improved (I) or worsened (W) based on a dichotomized anchor question related to self-perceived change in physical function, and the dichotomized change in KOOS-PS until 1-year follow-up. This led to 4 groups: (II, IW, WI, and WW).Results: Agreement was found with a DOR of 11.3 (CI 7.9–16.2). 2,335 (94%) reported improved function on the anchor question and 143 (6%) worsened function. Among those with improved anchor 2,132 (91%) had improved KOOS-PS, but among those with worsened anchor only 74 (52%) had worsened KOOS-PS. Pain at 1-year follow-up was lower in the groups reporting improved anchor.Conclusion: The KOOS-PS can be replaced with an anchor question to assess change in function until 1 year. However, the KOOS-PS might be a valuable supplement in patients reporting worsened anchor as only half of those had worsened KOOS-PS.
Evaluasi Antibodi dan Kejadian Ikutan Pasca Imunisasi (KIPI) Vaksin COVID-19 AstraZeneca Dosis Lengkap di Sentra Vaksin UTA'45 Jakarta
Authors: Lukas Stefanus 
Published: November 2024

Latar Belakang: AstraZeneca merupakan vaksin vektor virus. Vaksin adalah alat penting untuk membatasi kesehatan pandemi COVID -19. Vaksin ini memiliki metode yang lebih canggih yaitu menggunakan virus yang dimodifikasi untuk memicu antibodi guna menciptakan kekebalan kelompok (herd immunity) pada masyarakat. Tujuan : Mengevaluasi hubungan pemberian vaksin AstraZeneca terhadap nilai titer antibodi dan KIPI. Metode : Penelitian ini menggunakan metode retrospektif dan prospektif kohort Responden yang telah memenuhi kriteria inklusi dan ekslusi akan dijadikan sebagai responden dalam penelitian. Sebanyak 113 responden melakukan vaksinasi COVID-19 AstraZaneca dosis lengkap di Pusat Vaksin UTA’45 Jakarta. Setelah 7 hari pasca-vaksinasi, dilakukan pengukuran kadar titer antibodi dan gejala lokal dan sistemik KIPI selama 7 hari. Hasil: Jumlah responden yang pernah terpapar COVI-19 signfikan secara statistik terjadi pada jenis kelamin laki-laki, umur dibawah 35 tahun, disertai dengan penyakit penyerta (komorbid), aktif berolahraga, merokok dan tidak meminum alkohol. Sebanyak 38 (88.4%) orang dari 43 (38,05%) responden memiliki titer antibodi tinggi dan 5 orang (11,63%) dengan titer antibodi rendah. Tingginya kadar titer antibodi setelah vaksin COVID-19 berhubungan dengan munculnya gejala atau reaksi sistemik KIPI. Kesimpulan: Terdapat hubungan kadar titer antibodi COVID-19 dengan KIPI pasca vaksinasi
Pelatihan Pembuatan Pupuk Kompos Daun Kering di Sekolah Menengah Pertama Negeri (SMPN) 17 Kota Kupang
Authors: Kadja Agnes , Timung Helen Yohana , Wie Fitri 
Published: November 2024

SMPN 17 Kota Kupang memiliki lingkungan sekolah yang dihadapkan pada masalah serius terkait pengelolaan sampah, khususnya sampah dedaunan yang terbentuk akibat dedaunan yang melimpah di sekitar halaman sekolah. Sampah ini cenderung tertimbun tanpa pengelolaan yang baik, sehingga menyebabkan potensi pencemaran lingkungan dan membuat area sekolah menjadi kurang indah. tujuan kegiatan pelatihan ini yaitu memberikan pelatihan dan pendampingan pembuatan pupuk kompos daun kering bagi siswa-siswi kelas VII A SMPN 17 Kota Kupang. Metode yang digunakan adalah penyuluhan dan pendampingan secara langsung. Hasil dari Pelatihan pembuatan pupuk kompos dari daun kering ini menjadi solusi atas permasalahan pengelolaan sampah di SMPN 17 Kota Kupang dengan membuat sampah dedaunan menjadi produk yang bermanfaat dan memiliki nilai ekonomis, Dapat meningkatkan pengetahuan dan keterampilan (soft skill dan hard skill) dari siswa-siswi karena adanya pengalaman langsung tentang pembuatan pupuk kompos dari daun kering menggunakan cara sederhana, Terciptanya lingkungan sekitar sekolah yang lebih bersih dan nyaman dan Mengimplementasikan mata pelajaran prakarya dan kewirausahaan, sehingga siswa-siswa tidak hanya belajar teori tetapi juga melakukan prakteknya langsung.
Pemberdayaan Kelompok Penggerak Pariwisata (Kompepar) Pasir Batang melalui Pembuatan Pembibitan Tanaman Rehabilitasi
Authors: Supartono Toto , Nugraha Dadan , Wiharno Herma , Hidayatulloh Syahrul , Mafaz Mihra Fauzia , Anggraeni Dina Mariana , Menara Sekar Amalia 
Published: November 2024

The partner or target group for this community service activity is Kompepar Pasir Batang which is located in Karangsari Village, Darma District, Kuningan Regency. The activity area of Kompepar is the Pasir Batang Block which is part of the Gunung Ciremai National Park area. One of the problems faced by these partners is the difficulty of obtaining plant for rehabilitation activities around the partner's activity locations. Therefore, the aim of this service activity is to help provide a nursery for types of rehabilitation plants. The implementation methods used are counseling, training and empowerment. This activity can run smoothly as expected. This activity also received appreciation from the local village government and received full support from partners. Partners are actively involved in every stage of the activity. For the sustainability of the program, assistance by the Community Service Team will also continue so that the positive impact of the activities can be felt in real terms by many parties.
Multimodality of political digital discourse on Twitter social media
Authors: Suharto Abdul Wachid Bambang 
Published: November 2024

As a communication tool, social media has linguistic aspects ranging from letters to discourse, so it is important to be researched from a linguistic scientific point of view to find its meaning. This research aims to identify, elaborate, and analyze digital discourse on Twitter social media related to political elements. This research is based on the multimodal meaning related to communication modes in the form of signs such as writing, images, photos, videos, and other forms that have visual meaning in finding meaning in a communication in twitter posts. The method of this research is qualitative descriptive. The research data is in the form of posts on Twitter accounts that contain political elements. The data analysis technique in this study goes through the reduction and classification stage based on the use of communication modes in digital political discourse. Data collection techniques are carried out by documenting, listening, and taking notes. The results of the research are in the form of identification and explanation of how multimodal has meaning and meaning in digital political discourse on Twitter social media and the contribution of semiotic fashion in the form of writings, images, photos, videos, and other forms that have visual meaning in digital political discourse on Twitter social media as relevance regarding the views of the interests of discourse producers, digital discourse makers with certain semiotic modes to realize discourse, and interests aimed at the creation of political digital discourses such as identity politics, politics of struggle, and power politics.
Chickenpox in Poland in 2022
Authors: Zbrzeżniak Jakub Maciej , Paradowska-Stankiewicz Iwona 
Published: November 2024

IntroductionChickenpox is an infectious disease caused by the Varicella-zoster virus, usually affecting children. It is characterized by a rash with rapid seeding of small red papules. The course of the disease is mild, but in people with weakened immunity it may be severe.ObjectiveThe aim of the study was to assess the epidemiological situation of chickenpox in Poland in 2022 compared to the situation in previous years.Material and MethodsData from epidemiological surveillance, including mandatory reporting of cases by physicians, were used to assess the epidemiological situation of chickenpox in Poland.ResultsIn 2022, 171 708 cases of chickenpox were recorded, of which 87.5% were children under 9 years old. Hospitalization due to chickenpox was not one of the most common, the percentage of hospitalized cases oscillated between 0.12% and 1.24% depending on the voivodeship. Analyzing the incidence for the whole of Poland for the last 10 years, we see a drastic decrease from 470.6 in 2019 to 186.6 in 2020 and another decrease in 2021 to 151.1 per 100 000, to then return to an incidence of 453.9 in 2022.ConclusionThe incidence of chickenpox in 2022 returned to pre-pandemic levels, similar to those seen in 2016-2018. Despite preventive measures taken throughout the pandemic, significant incidence was observed, underlining the key role of vaccination in preventing this disease. The use of a quadrivalent vaccine against rubella, measles, mumps, and varicella could help reduce the costs associated with chickenpox, with a small increase in the costs of the vaccination program.
Virtual Reality as a support in psychotherapies for children with autism and/or social anxiety: a systematic review
Authors: Gómez Sánchez Lilia Guiodi , Lara López Graciela , Orozco Luna Felipe de Jesús 
Published: November 2024

ABSTRACT
Purpose
The growth of Virtual Reality (VR) applications for therapies has increased and diversified over time. Through VR, patients are encouraged to immerse themselves in virtual environments to interact and socialize. In this article we analyze the therapies that apply VR, as a strategy that addresses health needs, to improve the patient’s quality of life in mental disorders such as anxiety and autism spectrum. Furthermore, we compare the similarities and differences of the therapies, evaluating the efficacy of VR. Finally, we present a review of VR from a technological point of view.
Methods
The literature search was guided by PRISMA guidelines; study eligibility criteria: year of publication from 2014 to 2022, full-length and open access articles. Articles to improve social skills in children and adolescents with autism, as well as in addressing social anxiety in youth. Exclusion criteria: systematic reviews, meta-analyses, comorbidity, postoperative, and other disorders.
Results
We considered 14 eligible studies, with a low risk of bias. 78% of VR therapies were implemented immersively and 85% interactively, involving active user participation in virtual environments through voice, gaze, and body movements. VR therapies for children with ASD focus on the development of social skills, with facial expression recognition, emotion recognition, social cognitive development, and verbal and non-verbal communication. VR therapies for social anxiety are effectively treated with meditation and progressive muscle relaxation.
Conclusion
VR can simplify the lives of those patients who are unable to leave home, due to illness or disability, allowing them to comply with therapy sessions.
Tratamiento de la Vaginosis Bacteriana recurrente, actualización 2023
Authors: Espitia de la Hoz Franklin 
Published: November 2024

Introducción: a pesar de los múltiples tratamientos para la vaginosis bacteriana, más de la mitad de las mujeres experimentan recurrencia de los síntomas. Objetivo: evaluar la efectividad y seguridad de las intervenciones terapéuticas en el manejo de la vaginosis bacteriana recurrente, en mujeres no gestantes. Métodos: se realizó una búsqueda sistemática de la literatura en diferentes bases de datos electrónicas (MEDLINE, Scopus, Embase, Biblioteca Cochrane, entre otras); entre 1990 y 2023. Se utilizaron términos de búsqueda libres y estandarizados. Los desenlaces evaluados fueron el tiempo de retardo en la aparición de VB mayor a 12 meses y las reacciones adversas. Resultados: se tuvieron en cuenta 84 publicaciones. El metronidazol y la clindamicina siguen siendo el régimen terapéutico recomendado en el tratamiento de la vaginosis bacteriana aguda, y en la recurrente; el secnidazol y nifuratel han mostrado su positivo efecto, escalonando una posición entre estos regímenes (los cuales no solo podrían aumentar las tasas de curación clínica y microbiológica, sino disminución en la recurrencia). La proporción de reacciones adversas fueron más notables con los nitroimidazoles y la clindamicina, sin hallarse reportes del nifuratel. Conclusión: la revisión mostró que en el tratamiento de la vaginosis bacteriana recurrente no se observan diferencias significativas entre los regímenes tradicionales, lo mismo sucede con la seguridad, ya que las reacciones adversas son escasas y no suelen ser graves. Se necesitan ensayos clínicos que ayuden a aumentar las opciones de tratamiento para la VB recurrente, dándole paso al nifuratel y a otras opciones terapéuticas.
Chromatographic analysis of ponatinib and its impurities: method development, validation, and identification of new degradation product
Authors: Wang Jing , Zhu Yonghong , Qin Jisu , Wu Wenyi , Huang Rongrong , Cai Liangliang 
Published: November 2024

BackgroundPonatinib, a third-generation tyrosine kinase inhibitor, is employed in the management of adult chronic myeloid leukemia. Nevertheless, the presence of process impurities and degradation impurities linked to ponatinib may potentially influence its effectiveness and safety. Therefore, the objective of this research was to establish a robust liquid chromatography method and systematically validate it for the detection of substances related to ponatinib.MethodsThe separation of ponatinib and its impurities was conducted using an Agilent 5HC-C18 chromatographic column (4.6 mm × 250 mm, 5 μm). The mobile phase A comprised a mixture of water and acetonitrile in a 9:1 ratio, with an aqueous solution of pH 2.4 containing 2 mM potassium dihydrogen phosphate and 0.4% triethylamine. Mobile phase B, consisting of acetonitrile, was eluted in a gradient fashion. The flow rate was set at 1.0 mL/min, detection wavelength at 250 nm, column temperature at 40°C, and injection volume at 10 μL.ResultsThe method demonstrated high specificity, sensitivity, solution stability, linearity, precision, accuracy, and robustness. Additionally, this research unveiled a novel compound, imp-B, generated via the oxidative degradation of ponatinib. The molecular structure of the newly discovered product was elucidated through the utilization of nuclear magnetic resonance (NMR) and high-resolution mass spectrometry (HRMS).ConclusionIn conclusion, the chromatographic method developed in this study has the potential to be utilized for the detection of ponatinib and its impurities, thereby offering significant insights for quality assessment in ponatinib research.
Advances in the study of oral microbiota and metabolism associated fatty liver disease: a systematic review
Authors: Huang Mingming , Zhang Xinbi , Zhou Rui , Song Yingzhe , Zhang Jing , Wu Jian 
Published: November 2024

ObjectiveThe oral microbiota is the second largest microbiota in the human body and has a significant impact on human health. Recent evidence suggests that dysbiosis of the oral microbiota may be associated with the development of metabolism-associated fatty liver disease (MAFLD). This review aimed to validate the relationship between oral microbial diversity and the development of MAFLD.MethodsA systematic evaluation was performed based on PRISMA guidelines. Three independent reviewers searched for relevant literature in several databases, including PubMed/Medline, Web of Science, and Scopus, with a search date ranging from the establishment of the databases to June 2024.ResultsA total of 1278 publications were initially screened, including five cross-sectional studies, seven case-control studies, one cohort study, and one retrospective study. These studies included a total of 3335 patients with MAFLD, 254 patients with MASH, and 105 patients with liver cirrhosis. All 14 included studies concluded that there was a correlation or potential correlation between oral microbiota and MAFLD. Seven studies found that the composition of the oral microbiota in MAFLD patients differed from that of healthy controls, and specific oral bacteria may be associated with an increased incidence of MAFLD. At the phylum level, several studies found differences in the abundance of the phyla Firmicutes, Proteobacteria, and Clostridia compared to healthy controls. Additionally, a study on oral fungi found significant differences in the phyla Proteobacteria and in the genus Staphylococcus between patients with MAFLD and healthy controls. At the genus level, Porphyromonas was studied most frequently, with all 8 studies identifying infection with Porphyromonas as a significant risk factor for pathological progression in MAFLD. Furthermore, a dysbiosis in the ratio of Porphyromonas gingivalis./Porphyromonas anomalies may be an important marker of MAFLD progression.ConclusionThere is an important association between the diversity of oral microbiota composition and MAFLD. This finding suggests the importance of oral health assessment and monitoring for the prevention or intervention of MAFLD.
Association between estimated glucose disposal rate and female infertility: a cross-sectional study
Authors: Li Meng , Zhang Lisong , Li Xiaoyu , Yan Weisheng 
Published: November 2024

BackgroundInsulin resistance (IR) can lead to infertility in women. The primary objective of this research was to examine how estimated glucose disposal rate (eGDR) correlates with infertility in women, assessing its validity as an indicator of IR.MethodsData from the National Health and Nutrition Examination Survey spanning 2013 to 2018 were analyzed in this study. In order to investigate the correlation between eGDR and the prevalence of female infertility, this study used a combination of weighted multivariate regression analysis, restricted cubic spline (RCS) analysis, subgroup analyses, sensitive analysis, and receiver operating characteristic (ROC) curves.ResultsThis study enrolled 2541 women, with an average age of (32.52 ± 0.23) years. The overall infertility rate was 14.27%. A negative relationship was observed between eGDR levels and female infertility. Each increment of one unit in eGDR was linked to a 14% reduction in infertility incidence (OR = 0.86, 95% CI 0.80–0.94). RCS analysis revealed a nonlinear, inverse correlation between eGDR and female infertility. Subgroup analyses indicated that age influenced the association between eGDR and female infertility. The ROC curve suggested that eGDR was significantly better than HOMA-IR in predicting infertility [eGDR: 0.632 (95% CI: 0.603, 0.660) vs. HOMA-IR: 0.543 (95% CI: 0.514, 0.572)].ConclusionThere was an observed association where lower eGDR levels were linked with higher rates of female infertility. These results emphasize the significance of implementing measures to manage IR to protect women’s reproductive health.
Prevalence of occupational injuries and associated factors among solid waste collectors in Jigjiga city, eastern Ethiopia: a cross-sectional study design
Authors: Abib Muktar , Tolera Sina Temesgen , Hashi Abdiwahab , Mulugeta Yohannes , Temesgen Liku Muche 
Published: November 2024

BackgroundSolid waste collectors play an important role in maintaining health and hygiene in cities globally. The risk levels are very high in low-income countries since solid waste collectors have low socio-economic status and are exposed directly, unknowingly, and without adequate personal protection to municipal solid waste that contains hazardous materials. Solid waste collectors in Ethiopia are at high risk of occupational injuries due to the manual collection of hazardous solid waste by hand. In Jigjiga city, so far, there has been no study or published research showing the prevalence of occupational injuries and associated factors among municipal solid waste collectors.ObjectiveTo assess the prevalence of occupational injuries and associated factors among solid waste collectors in Jigjiga City, Somali Regional State, Ethiopia, 2023.MethodsAn institutional cross-sectional study was conducted in Jigjiga City, Somali Regional State, involving 247 solid waste collectors. Data was collected through an observational and structured questionnaire and analyzed using Epi Info and STATA software programs. The study used systematic random sampling techniques and bivariate and multivariable logistic regression analyses to determine the statistical association between the outcome variable and independent variables. The significance of the association was tested using the 95% confidence interval and p value (&lt;0.05).ResultsThe overall prevalence of occupational injuries was 54.7% (95% CI: 48.2%, 60.6%). Training on health and safety measures before employment [AOR: 0.43, 95% CI (0.24, 0.80)], sleeping problems [AOR: 3.28, 95% CI (1.86, 5.78)] and Temporary workers [AOR: 2.14, 95% CI (1.16, 3.95)] were significantly associated with occupational injuries.ConclusionThe prevalence rate of occupational injuries among solid waste collectors in Jigjiga City was high. There should be preventive measures, like giving Training on Health and safety before employment, to safeguard the health and safety conditions of the workers.