bluuebunny/crossref_metadata_2025_split huggingface dataset:
Faith in school: balancing no establishment and free exercise of religion guarantees in American education
Authors: Witte John 
Published: October 2024

AbstractAmerican schools are governed by a complex lattice work of federal, state, and local laws and regulations, many of them tailored specifically to primary, secondary, or higher education. But all schools are subject to the same First Amendment guarantee that ‘Congress shall make no law respecting an establishment of religion or prohibiting the free exercise thereof’. This constitutional guarantee of religious freedom has produced a substantial body of case law. Nearly one-third of the United States Supreme Court's cases on religious freedom – 74 out of its 247 cases reported from 1815 to 20231 – have addressed issues of religion and education. All but six of these cases were decided after 1940, the year the Court first began to apply these guarantees to state and local governments alongside ‘Congress’;2 and for each Supreme Court case, there are scores of lower federal court and sometimes state court cases that add further nuance and amplification. This article summarises, and critically analyses, this ever-evolving jurisprudence.
Revisiting the Rustat case
Authors: Higton Mike 
Published: October 2024

In May 2021, Jesus College Cambridge submitted to the Diocese of Ely a ‘faculty petition’ – that is, a formal request to alter the fabric of an ecclesiastical building – asking for permission to remove from the west wall of the college chapel a large memorial to Tobias Rustat, ‘because of Rustat's known involvement in the transatlantic trade in enslaved Africans’. On 23 March 2022, following hearings the month before, Hodge Dep Ch provided a written judgment in which he denied the application. The college, he said, had not provided a convincing case that the removal of the monument was ‘necessary to enable the Chapel to play its proper role in providing a credible Christian ministry and witness to the College community’, and such a case was needed to outweigh the ‘considerable, or notable, harm’ that would result from the removal ‘to the significance of the Chapel as a building of special architectural or historic interest’.
Power and its exercise in the Vatican City State
Authors: Dyda Konrad 
Published: October 2024

AbstractThe problem of relations between Church and state has existed from the very beginnings of Christianity and has evolved over centuries. The dominant model today is one of separation between the state and religious communities. In the context of the Roman Catholic Church, the Vatican City State remains the only exception to this principle. This article examines the tensions inherent in the way in which the Roman Pontiff, as head of the Vatican City State, exercises both religious and secular power, and how rule of law principles operate to constrain the operation of power as between the various organs of this state.
Body temperature and thermoregulatory behaviour in the Endangered African Penguin Spheniscus demersus
Authors: Welman Shaun , Green Jonathan A. , Ryan Peter G. , Parsons Nola J. , Pichegru Lorien 
Published: October 2024

Summary
Heat stress from high temperatures has been recognised as a threat to several bird species and one that is likely to increase in severity and frequency as a result of global environmental change. Many seabirds are particularly vulnerable as their adaptations to forage in cold water can make it hard for them to resist heat gain while on land. The African Penguin Spheniscus demersus forages in cool water (10–20°C) but breeds and moults on land where temperatures can exceed 30°C. Little is known about its thermal physiology and when heat stress will occur. Here, we provide the first account of changes in body temperature and behaviour in African Penguins in response to an experimental increase in ambient temperature from 20°C to 35°C. Surprisingly, the highest body temperature observed (39.2°C) was recorded at the start of the study. Presumably, this response in body temperature was due to the stress of transport and handling. Penguins returned to normal body temperature (37.3°C) after 3.5 hours and maintained normothermia for roughly an hour. We then observed the onset of heat storage at an ambient temperature of 29°C, whereafter body temperature increased steadily at a rate of ca.0.2°C per 1°C increase in ambient temperature. Panting commenced at an ambient temperature of 31.4°C, when body temperature was 37.8°C. In addition to panting, penguins changed their posture to facilitate heat dissipation by standing, raising their heads, and extending their flippers. Our results corroborate field observations and support the argument that African Penguins are highly vulnerable to heat stress in the near future as extreme heat events become more severe and frequent due to climate change. Our results also confirm that penguins are sensitive to handling, which elicits a hyperthermic response. Given the general sensitivity of penguins to disturbance, from a conservation perspective, we advise that cautionary measures be implemented at colonies during critical life-history stages.
Clinical management model for impulse control disorders in Parkinson’s disease
Authors: Li Han , Yang Yong , Yang Liying , Xie Anmu 
Published: October 2024

AbstractOver the last decade, we have gained a better understanding of impulse control disorder in Parkinson’s disease (PD-ICD), a medication complication in PD. Researchers were aware of its complexity and took efforts to learn more about its diagnostic and treatment possibilities. Nevertheless, clinical management for it is currently neglected. We conducted a narrative overview of literature published from 2012 to October 2023 on various aspects of clinical management for PD-ICD. A potential “susceptibility-catalytic-stress” model in the development of PD-ICD was proposed and a profile encoding predictors for PD-ICD was created. Based on these predictors, some methods for prediction were recently developed for better prediction, such as the polymorphic dopamine genetic risk score and the clinic-genetic ICD-risk score. A variety of treatment options, including dose reduction of dopamine receptor agonists (DAs), DAs removal, DAs switch, and add-on therapy, are investigated with inconsistent reports. Based on current findings, we developed a clinical management model prototype centered on prevention, consisting of prediction, prevention, follow-up and monitoring, therapy, and recurrence prevention, for clinical reference, and further proposed 4 key clinical management principles, including standardization, prediction centered, persistence, and whole course.
Minimizing risks of off-target movement of florpyrauxifen-benzyl by coating onto urea
Authors: Cotter Bodie L. , Norsworthy Jason K. , Butts Thomas R. , Roberts Trenton L. , Mauromoustakos Andy 
Published: October 2024

Abstract
Commercialization of florpyrauxifen-benzyl as Loyant® in 2018 as a synthetic auxin herbicide in rice was followed by soybean injury due to off-target movement of spray applications in the mid-southern United States. Concerns surrounding off-target movement led to the exploration of an alternative application method to help alleviate the issue. Field experiments were conducted in 2020 and 2021 to explore the likelihood of a reduction in soybean injury following applications of florpyrauxifen-benzyl coated on urea in narrow- and wide-row soybean systems and to determine the likelihood of volatilization from this novel application method. Florpyrauxifen-benzyl spray-applied at 0.18 g ai ha−1 caused greater than 60% injury, whereas coating the herbicide on urea at 5.63 g ai ha−1 never exceeded 30% injury in narrow-row soybean. Similarly, florpyrauxifen-benzyl spray-applied at 0.18 g ai ha−1 caused greater than 50% injury, whereas coating the herbicide on urea at 5.63 g ai ha−1 never exceeded 30% injury in wide-row soybean. As soybean injury increased, relative yield decreased in both narrow- and wide-row soybean. Spray-applied florpyrauxifen-benzyl decreased relative soybean groundcover, yield components, and soybean survival rate as the herbicide rate increased, whereas coating the herbicide on urea resulted in little to no decrease in both narrow- and wide-row soybean assessments. No negative impacts on relative yield and yield components of soybean from florpyrauxifen-benzyl coated on urea indicates that even though visible injury may persist, there is a low likelihood of any yield losses associated with the herbicide exposure using this application method. Additionally, coating the florpyrauxifen-benzyl on urea did not increase the likelihood of volatilization under any of the evaluated soil moisture conditions. Overall, applying florpyrauxifen-benzyl coated on urea is likely to be a safer application method and can reduce soybean injury compared to spray-applying the herbicide when favorable off-target movement conditions exist.
A Trp-574-Leu mutation in acetolactate synthase confers imazamox resistance in barnyardgrass (Echinochloa crus-galli) from China
Authors: Liu Yu , Shi Kerong , Gao Haitao , Yin Shaojing , Dong Liyao , Feng Zhike 
Published: October 2024

AbstractBarnyardgrass [Echinochloa crus-galli (L.) P. Beauv.] is increasingly infesting imidazolinone-tolerant (IMI-T) rice (Oryza sativa L.) fields in China, and E. crus-galli imazamox resistance has become the major concern for weed management in IMI-T rice fields. In this study, the susceptible population JLGY-3 (S) and the suspected resistant population JHXY-2 (R) collected from IMI-T rice fields were used as research subjects. When treated with imazamox, the JHXY-2 (R) population showed a high level of herbicide resistance with a resistance index of 31.2. JHXY-2 (R) was cross-resistant to all five acetolactate synthase (ALS) inhibitors from different chemical families, but sensitive to herbicides inhibiting acetyl-CoA carboxylase. To understand the reason why JHXY-2 (R) was resistant to imazamox, we performed experiments to characterize potential target-site resistance (TSR) and non–target site resistance (NTSR) mechanisms. A Trp-574-Leu amino acid mutation in ALS and low imazamox ALS sensitivity were the main mechanisms underlying imazamox resistance in this JHXY-2 (R) population. There was no significant difference in ALS gene expression and ALS protein abundance between R and S populations. High-performance liquid chromatography–tandem mass spectrometry analysis showed enhanced metabolism of imazamox in JHXY-2 (R), which was in contrast to the results of pretreatment with a metabolic enzyme inhibitor. Treatments with cytochrome P450 monooxygenase/glutathione S-transferase (P450/GST) inhibitors did not alter the resistance level of JHXY-2 (R) against imazamox. Transcriptome sequencing showed that there was almost no significant difference in the expression of P450 and GST metabolic enzyme genes between R and S populations, and only GSTU1 showed a significant upregulation in the R population, further clarifying the NTSR mechanism of JHXY-2 (R). In conclusion, amino acid mutation and higher enzyme activity of ALS are the main causes of imazamox resistance in JHXY-2 (R). However, given the differences in imazamox residues in the leaves of E. crus-galli, there may still be undetectable NTSR mechanisms that are causing imazamox resistance in the R population.
Electric interrow control of lupine plants does not adversely affect the neighboring non-target lupine plants
Authors: Borger Catherine P.D. , Slaven Miranda J. 
Published: October 2024

Abstract
Interrow weed control is used in a wide range of crops, traditionally applied via physical cultivation or banded herbicide application. However, these methods may result in crop damage, development of herbicide resistance, or off-target environmental impacts. Electric interrow weed control presents an alternative, although its potential impact on crop yield requires further investigation. One of the modes of action of electric weed control is the continuous electrode–plant contact method, which passes a current through the weed and into the roots. As the current passes into the roots, it can potentially disperse through the soil to neighboring root systems. Such off-target current dispersion, particularly in moist topsoil with low resistance, poses potential concern for neighboring crops when electric interrow weed control is applied. This research evaluated the continuous electrode–plant contact method, using a Zasso™ XPower machine, in comparison with mowing across three trials conducted in 2022 and 2023. Both treatments were used to remove target lupine (Lupinus albus L.) plants adjacent to a row of non-target lupine. Electric weed control was applied to plants in dry soil or following a simulated rainfall event. The trials demonstrated that electric weed control and mowing did not reduce density and biomass of neighboring non-target lupine plants compared with the untreated control. Likewise, pod and seed production, grain size, and protein, as well as grain germinability and vigor of the resulting seedlings, were not reduced by these weed control tactics. This research used technology that was not fit for purpose in broadscale grain crops but concludes that electric weed control via the continuous electrode–plant contact method or mowing did not result in crop damage. Therefore, it is unlikely that damage will occur using commercial-grade electric weed control or mowing technology designed for large-acreage interrow weed control, thus offering nonchemical weed management options.
Solid Earth Carbon Degassing and Sequestration Since 1 Billion Years Ago
Authors: Müller R. Dietmar , Dutkiewicz Adriana , Zahirovic Sabin , Merdith Andrew S. , Scotese Christopher R. , Mills Benjamin J. W. , Ilano Lauren , Mather Ben 
Published: October 2024

AbstractSolid Earth CO2 outgassing, driven by plate tectonic processes, is a key driver of carbon cycle models. However, the magnitudes and variations in outgassing are poorly constrained in deep‐time. We assess plate tectonic carbon emissions and sequestration by coupling a plate tectonic model with reconstructions of oceanic plate carbon reservoirs and a thermodynamic model to quantify outfluxes from slabs and continental arcs over 1 billion years. In the early Neoproterozoic, our model predicts a peak in crustal production and net outgassing from 840 to 780 Ma that corresponds to a contemporaneous pulse in large igneous province eruptions. The Sturtian and Marinoan glaciations (717–635 Ma) correspond to a low in mid‐ocean ridge outgassing, while the following Ediacaran global warming coincides with a rise in net atmospheric carbon influx, driven by an increase in plate boundary and rift length. The Cambrian, Silurian/Devonian and Triassic Jurassic hothouse climates are synchronous with a reduction in carbon sequestration flux into oceanic plates, increasing net outgassing. In contrast, the Early Cretaceous hothouse climate is accompanied by a pronounced increase in mid‐ocean ridge outgassing. Both the Early Ordovician cooling and the late Paleozoic ice ages coincide with a significant decrease in net atmospheric outgassing, driven by an increase in carbon sequestration. The late Cenozoic glaciation is associated with a long‐term decrease in mid‐ocean ridge and rift degassing, and a pronounced increase in carbon flux into pelagic carbonate sediments. Our tectono‐thermodynamic carbon cycle model provides a new foundation for future long‐term climate and geochemical cycling models.
Phase Transitions and Thermal Equation of State of Fe‐9wt.%Si Applied to the Moon and Mercury
Authors: Berrada Meryem , Chen Bin , Chao Keng‐Hsien , Peckenpaugh Juliana , Wang Siheng , Zhang Dongzhou , Nguyen Phuong , Li Jie 
Published: October 2024

AbstractAccurate knowledge of the phase transitions and thermoelastic properties of candidate iron alloys, such as Fe‐Si alloys, is essential for understanding the nature and dynamics of planetary cores. The phase diagrams of some Fe‐Si alloys between 1 atm and 16 GPa have been back‐extrapolated from higher pressures, but the resulting phase diagram of Fe83.6Si16.4 (9 wt.% Si) is inconsistent with temperature‐induced changes in its electrical resistivity between 6 and 8 GPa. This study reports in situ synchrotron X‐ray diffraction (XRD) measurements on pre‐melted and powder Fe83.6Si16.4 samples from ambient conditions to 60 GPa and 900 K using an externally heated diamond‐anvil cell. Upon compression at 300 K, the bcc phase persisted up to ∼38 GPa. The hcp phase appeared near 8 GPa in the pre‐melted sample, and near 17 GPa in the powder sample. The appearance of the hcp phase in the pre‐melted sample reconciles the reported changes in electrical resistivity of a similar sample, thus resolving the low‐pressure region of the phase diagram. The resulting high‐temperature Birch‐Murnaghan equation of state (EoS) and thermal EoS based on the Mie‐Gruneisen‐Debye model of the bcc and hcp structures are consistent with, and complement the literature data at higher pressures. The calculated densities based on the thermal EoS of Fe‐9wt.%Si indicate that both bcc and hcp phases agree with the reported core density estimates for the Moon and Mercury.
Influence of Organo‐Mineral Associations on Terrestrial Particulate Organic Matter Dispersal in the Northern Gulf of Mexico
Authors: Yedema Yord W. , Sangiorgi Francesca , Trabucho‐Alexandre João P. , Nierop Klaas G. J. , Vonk Jorien E. , Peterse Francien 
Published: October 2024

AbstractWe investigate the influence of organo‐mineral associations on the dispersal of terrestrial organic matter (TerrOM) along a land‐sea transect offshore the Atchafalaya river in the northern Gulf of Mexico (GoM). We analyzed bulk sediment properties, mineral surface area, and clay composition and used lipid biomarkers to distinguish plant‐derived (long‐chain n‐alkanes and n‐alcohols) freshwater aquatic (C32 1,15‐diols) and soil‐microbial (branched glycerol dialkyl glycerol tetraethers (brGDGTs)) OM‐pools in different grain size fractions (≥250, 250–125, 125–63, 63–30, 30–10 and <10 μm) of marine surface sediments. Concentrations and mineral loadings of the targeted biomarkers were highest in the <30 μm fractions, suggesting an affinity with clay minerals. Spatially, concentrations of higher plant‐derived n‐alkanes remained relatively constant along the transect, whereas those of the other OM‐pools rapidly decreased further offshore. This suggests that the association of plant‐derived OM with mineral surfaces is better maintained than that of freshwater and soil‐microbial OM. In addition, similar distributions among grain size fractions at each site for the C32 1,15‐diols and brGDGTs suggest that these compounds are likely not associated with mineral surfaces in the marine realm. Furthermore, as TerrOM might be stripped from mineral surfaces upon discharge in the marine realm, the dispersal of TerrOM‐pools could also represent a degradation signal, as n‐alkanes are more resistant than long‐chain diols and brGDGTs. Together, our results indicate that the stability of organo‐mineral associations in the marine realm differs per TerrOM‐pool and can lead to a differential dispersal of these pools, and thus OM sequestration patterns in the northern GoM.
Shape optimization for high efficiency metasurfaces: theory and implementation
Authors: Dainese Paulo , Marra Louis , Cassara Davide , Portes Ary , Oh Jaewon , Yang Jun , Palmieri Alfonso , Rodrigues Janderson Rocha , Dorrah Ahmed H. , Capasso Federico 
Published: October 2024

AbstractComplex non-local behavior makes designing high efficiency and multifunctional metasurfaces a significant challenge. While using libraries of meta-atoms provide a simple and fast implementation methodology, pillar to pillar interaction often imposes performance limitations. On the other extreme, inverse design based on topology optimization leverages non-local coupling to achieve high efficiency, but leads to complex and difficult to fabricate structures. In this paper, we demonstrate numerically and experimentally a shape optimization method that enables high efficiency metasurfaces while providing direct control of the structure complexity through a Fourier decomposition of the surface gradient. The proposed method provides a path towards manufacturability of inverse-designed high efficiency metasurfaces.
Machine learning-driven discovery of high-performance MEMS disk resonator gyroscope structural topologies
Authors: Chen Chen , Zhou Jinqiu , Wang Hongyi , Fan Youyou , Song Xinyue , Xie Jianbing , Bäck Thomas , Wang Hao 
Published: October 2024

AbstractThe design of the microelectromechanical system (MEMS) disc resonator gyroscope (DRG) structural topology is crucial for its physical properties and performance. However, creating novel high-performance MEMS DRGs has long been viewed as a formidable challenge owing to their enormous design space, the complexity of microscale physical effects, and time-consuming finite element analysis (FEA). Here, we introduce a new machine learning-driven approach to discover high-performance DRG topologies. We represent the DRG topology as pixelated binary matrices and formulate the design task as a path-planning problem. This path-planning problem is solved via deep reinforcement learning (DRL). In addition, we develop a convolutional neural network-based surrogate model to replace the expensive FEA to provide reward signals for DRL training. Benefiting from the computational efficiency of neural networks, our approach achieves a significant acceleration ratio of 4.03 × 105 compared with FEA, reducing each DRL training run to only 426.5 s. Through 8000 training runs, we discovered 7120 novel structural topologies that achieve navigation-grade precision. Many of these surpass traditional designs in performance by several orders of magnitude, revealing innovative solutions previously unconceived by humans.
Characteristics and outcomes of therapy-related acute leukemia following autologous transplant (Auto-HCT) for multiple myeloma
Authors: Elghawy Omar , Deshpande Saarang , Sussman Jonathan , Garfall Alfred , Cohen Adam , Kapur Shivani , Susanibar-Adaniya Sandra , Vogl Dan , Waxman Adam , Stadtmauer Edward 
Published: October 2024

AbstractWith a prolonging duration of survivorship, patients with multiple myeloma (MM) who receive high-dose chemotherapy and autologous hematopoietic stem cell transplantation (auto-HCT) have an increased risk of secondary malignancy, most concerning acute leukemia. We retrospectively reviewed the records of all patients with MM who underwent auto-HCT between January 1, 2010, and January 1, 2023, who later developed therapy-related acute leukemia (t-AL). Of 1770 patients with MM who underwent auto-HCT, 18 (1.01%) developed t-AL at a mean interval of 60.0 ± 41.3 months after auto-HCT. The patients with t-AL consisted of 9 (50%) with B-cell acute lymphoblastic leukemia (B-ALL), 8 (44.4%) with acute myeloid leukemia (AML), and 1 (5.6%) with acute promyelocytic leukemia (APML). All patients had received an alkylating agent as part of induction, and the majority received lenalidomide as maintenance therapy. Genetic abnormalities of t-AL were consistent with prior reports. Median overall survival from diagnosis of t-AL was 19.5 months. In patients with t-AL who entered CR, long term survival was common. Further research on predisposing conditions to developing t-AL in patients with MM undergoing auto-HCT is warranted.