bluuebunny/crossref_metadata_2025_split huggingface dataset:
The search for the imperfect language
Authors: Leone Massimo 
Published: October 2019

AbstractThe meta-semiotic ideology that underpins most contemporary semiotics seems at odds with the one that underlies the attempt at planning and creating a new language. Semiotics, as well as modern linguistics, has increasingly evolved into a substantially descriptive endeavor, excluding any consistent normative purpose. Faithful to the epistemology of Ferdinand de Saussure, semiotics does not primarily aim at either pointing at some supposed flaws of such or such language or at proposing some new linguistic forms meant to fix them. The article analyses linguistic utopias from the perspective of present-day semiotics.
What is political semiotics and why does it matter? A reply to Janar Mihkelsaar
Authors: Selg Peeter , Ventsel Andreas 
Published: October 2019

AbstractIn view of the recent criticisms of Janar Mihkelsaar the authors explicate their position on what political semiotics is and why it is important for both semiotics and the social sciences. Some further research trajectories are also discussed in moving from semiotic theory of hegemony to fully developed subdiscipline of political semiotics that would be part of the “relational turn” in political analysis more generally.
Zur Gründung von gemeinwesenorientierten Genossenschaften
Authors: Thürling Marleen 
Published: October 2019

ZusammenfassungSeit Beginn der 2000er Jahre gründen sich vermehrt gemeinwesenorientierte Genossenschaften in den Bereichen Infrastruktur, Daseinsvorsorge und Soziales. Vor dem Hintergrund bestehender Versorgungsprobleme vor allem im ländlichen Raum, werden diese Gründungen zunehmend als mögliche Lösungen zur Erbringung von Angeboten und Dienstleistungen der Daseinsvorsorge diskutiert. Gleichzeitig gibt es bislang nur wenig empirisch gesicherte Erkenntnisse zu diesem Phänomen. Auf der Grundlage der Neugründungsstatistik der DZ Bank wurden im Rahmen eines Forschungsprojekts am Institut für Genossenschaftswesen der Humboldt-Universität zu Berlin die Gründung von Genossenschaften in den Bereichen der Daseinsvorsorge, Infrastruktur und Soziales in den Jahren 2006 und 2018 erhoben. Untersucht wurde, wo diese Genossenschaften gegründet wurden; dabei zeigen sich deutliche regionale Unterschiede, die Hinweise auf folgende Fragen liefern: sind diese Genossenschaften eine Reaktion auf besondere Strukturschwäche und Problemlagen, oder entstehen sie dort, wo Gründer*innen besonders gute Rahmenbedingungen und entsprechende Ressourcen für die Gründung vorfinden.
Determinación del porcentaje de viabilidad espermática mediante citometría de flujo durante el proceso de criopreservación en espermatozoides obtenidos de epidídimo de alpaca
Authors: Juárez Javier , Santiani Alexei 
Published: October 2019

El objetivo del estudio fue determinar el porcentaje de viabilidad en espermatozoides epididimarios de alpaca, antes y después del proceso de criopreservación, mediante citometría de flujo. Se recolectaron 46 testículos de alpaca de un camal de Pasco, Perú y se utilizaron 41 de ellos con motilidad espermática ≥30% y concentración espermática ≥50x106 espermatozoides/ml. Los espermatozoides fueron recuperados de la cola del epidídimo con 1 ml de dilutor a base de leche descremada. separándose en dos alícuotas para evaluar la viabilidad antes y después del proceso de criopreservación. El dilutor fue retirado mediante lavados por centrifugación con PBS, los pellets fueron resuspendidos en 100 µl de PBS, agregándose 0.5 µl de SYBR-14 (100 nM) y 0.5 µl de ioduro de propidio – PI (12 µM) incubándose por 10 min a 38 °C. La evaluación de viabilidad espermática se realizó mediante citometría de flujo con analizador de imágenes, utilizando un láser de excitación de 488 nm y la fluorescencia emitida por el SYBR-14 y el PI fueron detectados por los canales Ch02 (505-560 nm) y Ch05 (642-740 nm), respectivamente. Los espermatozoides viables con membrana intacta emitieron fluorescencia verde (SYBR-14) y los espermatozoides no viables con membrana dañada emitieron fluorescencia roja (PI). La viabilidad antes del proceso de criopreservación (48.97 ± 11.47%) fue mayor (p<0.05) que después del proceso de criopreservación (32.30 ± 9.57%). La correlación entre viabilidad y motilidad espermática fue r=0.6737. Se concluye que el proceso de criopreservación disminuye significativamente la viabilidad en espermatozoides epididimarios de alpaca, estando este parámetro relacionado con la motilidad.
Knowledge and Practice of Battery Technicians about Lead Poisoning in the Workplace
Authors: Zamani-Badi Hakime , Sarsangi Vali , Hannani Mitra , Akbari Hossein , Mazaheri Tehrani Ashraf 
Published: October 2019

Background: The sick building syndrome (SBS) is known as an unhealthy condition of occupants of a building, caused by environmental factors such as small space, poor ventilation, and different pollutants in the building. Symptoms of SBS include anxiety, respiratory, dermal, and sensory problems which start by entering a building or slightly after that, and disappear after leaving the building. The aim of this study was to determine the frequency of SBS in the employees of Shahid Beheshti hospital of Kashan. Methods: In a descriptive, cross-sectional study conducted, a sample of 279 randomly-selected employees of Shahid Beheshti hospital in Kashan working during 2016-2017, were involved. The study was performed on four groups of doctors, nurses, servants and employees. To collect the data; a questionnaire was used. It consisted of two parts: demographic data and questions of SBS questionnaire of World Health Organization. The collected data were analyzed using SPSS; and statistical tests such as Chi square and Fisher's exact test were performed and logistic regression were used for multivariate analysis. Results: The prevalence rate of SBS in general, in women and in men was estimated 50.81%, 55.3% and 44.7%, respectively. Symptoms of indisposition(47.3%), skin dryness (41.5%) and headaches (38.9%) had the highest frequency. Studying SBS symptoms in different job groups showed that skin dryness and dry and sore throat in physicians were significantly less than those in the other groups (p<0.05). In logistic regression analysis, the only factor influencing SBS was the staff height (p=0.02). Conclusion: Considering the high prevalence of the symptoms of building syndrome in all of the four groups, paying more attention to improving the working environment, such as the efficiency of the air conditioner system and increasing the entry of fresh air into the departments, increasing the quality of work life would be of utmost importance which would result in motivating and increasing the productivity in the work environment.
Cognitive factors management methodology for the production of high-tech enterprises
Authors: Gorlacheva E. N. , Ivannikova E. M. 
Published: October 2019

The purpose of the article is to outline the main provisions of the methodology for managing cognitive factors of production. It is shown that the processes of industrial re-industrialization, known as Industry 4.0, have led to the emergence of a new type of production resources – cognitive factors of production. The essence of the concept of “cognitive factors of production” is determined, a structural diagram of the methodology of managing cognitive factors of production is presented. Based on the methods of system analysis, an organizational and economic management model is developed and a mechanism for integration into the general control loop of an industrial enterprise is proposed. In conclusion, conclusions are drawn about the possibility of applying the methodology of managing cognitive factors of production in a knowledge-based economy.
Genes regulating biochemical pathways of oxygen metabolism in porcine oviductal epithelial cells during long-term IVC
Authors: Kocherova Ievgeniia , Brązert Maciej , Sujka-Kordowska Patrycja , Konwerska Aneta , Kulus Magdalena , Chermuła Błażej , Celichowski Piotr , Piotrowska-Kempisty Hanna , Antosik Paweł , Bukowska Dorota , Bruska Małgorzata , Pawelczyk Leszek , Zabel Maciej , Nowicki Michał , Kempisty Bartosz , Jeseta Michal 
Published: October 2019

Abstract
Oxygen metabolism has an important role in the normal functioning of reproductive system, as well as the pathogenesis of female infertility. Oxidative stress seems to be responsible for the initiation or development of reproductive organ diseases, including polycystic ovary syndrome, endometriosis, preeclampsia, etc. Given the important role of maintaining balance between the production of ROS and antioxidant defence in the proper functioning of reproductive system, in the present study we aimed to analyse the expression of genes related to oxygen metabolism in porcine oviductal epithelial cells during long-term in vitro culture. The oviducts were collected from 45 crossbred gilts at the age of approximately nine months that displayed at least two regular oestrous cycles. The oviductal endothelial cells were isolated by enzymatic digestion to establish long-term primary cultures. Gene expression changes between 7, 15 and 30 daysof culturewere analysed with the use ofwhole transcriptome profiling by Affymetrix microarrays. The most of the “cellular response to oxidative stress” genes were upregulated. However, we did not observe any main trend in changes within the “cellular response to oxygen-containing compound” ontology group, where the gene expression levels were changed in various manner.

Running title: Oxygen metabolism in porcine oviductal epithelial cells
Analysis of expression of genes responsible for regulation of cellular proliferation and migration – microarray approach based on porcine oocyte model
Authors: Chamier-Gliszczyńska Agata , Kałużna Sandra , Stefańska Katarzyna , Celichowski Piotr , Antosik Paweł , Bukowska Dorota , Bruska Małgorzata , Zakova Jana , Machatkova Marie , Jeseta Michal , Nowicki Michał 
Published: October 2019

Abstract
The formation of mammalian oocytes begins in the ovary during fetal development. The proper development of oocytes requires close communication with surrounding somatic cells, the substances they emit allow proper maturation of oocytes. Somatic cumulus (CC) cells and oocytes form cumulus-oocyte (COC) complexes.
In this study, the Affymetrix microarray analysis was used to investigate changes in gene expression occurring in oocytes before and after in vitro maturation (IVM). The aim of the study was to examine oocyte genes involved in two ontological groups, “regulation of cell migration” and “regulation of cell proliferation” discovered by the microarray method.
We found a reduced expression of all 28 genes tested in the ontological groups: ID2, VEGFA, BTG2, CCND2, EDNRA, TGFBR3, GJA, LAMA2, RTN4, CDK6, IHH, MAGED1, INSR, CD9, PTGES, TXNIP, ITGB1, SMAD4, MAP3K1, NOTCH2 , IGFBP7, KLF10, KIT, TPM1, PLD1, BTG3, CD47 and MITF. We chose the most regulated genes down the IVM culture, and pointed out those belonging to two ontological groups.
Increased expression of the described genes before IVM maturation may indicate the important role of these genes in the process of ovum maturation. After the maturation process, the proteins produced by them did not play such an important role. In summary, the study provides us with many genes that can serve as molecular markers of oocyte processes associated with in vitro maturation. This knowledge can be used for detailed studies on the regulation of oocyte maturation processes.

Running title: Genes regulating cellular migration and proliferation in porcine oocytes
Genes encoding proteins regulating fatty acid metabolism and cellular response to lipids are differentially expressed in porcine luminal epithelium during long-term culture
Authors: Kulus Magdalena , Borowiec Blanka , Popis Małgorzata , Celichowski Piotr , Jeseta Michal , Bukowska Dorota , Piotrowska-Kempisty Hanna , Bruska Małgorzata , Zabel Maciej , Nowicki Michał , Kempisty Bartosz , Antosik Paweł 
Published: October 2019

Abstract
Among many factors, the epithelium lining the oviductal lumenis very important for the development of the oocyte and its subsequent fertilization. The oviductal epithelium is characterized by the presence of ciliary cells, supporting the movement of cumulus-oocyte complexes towards the uterus. By interacting with the semen, the epithelium of the fallopian tube makes the sperm acquire the ability to fertilize. So far, the exact molecular mechanisms of these changes have not been known. Hence, understanding the metabolism of oviduct epithelial cells and the level of expression of individual groups of genes seems to be a way to deepen the knowledge about the broadly understood reproduction.
In our research, we decided to culture oviductal epithelial cells (OECs) in vitro for a long period of time. After 24h, 7, 15 and 30 days, the OECs were harvested, with their RNA isolated. Transcriptomic changes were analyzed using microarrays. The “cellular response to lipid” group was represented by the following genes: MUC1, CYP24A1, KLF4, IL24, SNAI2, CXCL10, PPARD, TNC, ABCA10, while the genes belonging to the “cellular lipid metabolic processes” were: LIPG, ARSK, ACADL, FADS3, P2RX7, ACSS2, PPARD, KITLG, SPTLC3, ERBB3, KLF4, CRABP2. Additionally, PPARD and ACADL were members of the “fatty acid beta-oxidation” ontology group. Our study describes genes that are not directly related to fertility processes. However, significant changes in their expression in in vitro cultured OECs may indicate their usefulness as markers of OECs’ physiological processes.

Running title: Fatty acids changes in porcine oviductal epithelial cells in in vitro cultivation
Association of severity of depressive symptoms with sleep quality, social support and stress among Pakistani medical and dental students: A cross-sectional study
Authors: Waqas Ahmed , Iftikhar Aqsa , Malik Zahra , Aedma Kapil Kiran , Meraj Hafsa , Naveed Sadiq 
Published: October 2019

Abstract

Objectives
This study has been designed to elucidate the prevalence of stress, depression and poor sleep among medical students in a Pakistani medical school. There is a paucity of data on social support among medical students in Pakistan; an important predictor of depressive symptoms. Therefore, this study was also aimed to demonstrate the direct and indirect impact of social support in alleviating depressive symptoms in the study sample.

Methods
This observational cross-sectional study was conducted in Lahore, Pakistan, where a total of 400 students at a medical school were approached between 1st January to 31st March 2018 to participate in the study. The study sample comprised of medical and dental students enrolled at a privately financed Pakistani medical and dental school. The participants responded to a self-administered survey comprising of five parts: a) demographics, b) Pittsburgh Sleep Quality Index (PSQI), c) Patient Health Questionnaire-9 (PHQ-9), d) Multidimensional Scale of Perceived Social Support (MSPSS) and e) Perceived Stress Scale-4 (PSS-4). All data were analysed using SPSS v. 20. Linear regression analysis was used to reveal the predictors of depression.

Results
In total, 353 medical students participated, yielding a response rate of 88.25%. Overall, poor sleep quality was experienced by 205 (58.1%) students. Mild to severe depression was reported by 83% of the respondents: mild depression by 104 (29.5%), moderate depression by 104 (29.5%), moderately severe depression by 54 (15.3%) and severe depression by 31 (8.8%) respondents. Subjective sleep quality, sleep latency, daytime dysfunction and stress levels were significantly associated with depression symptoms. Social support was not significantly associated with depressive symptoms in the regression model (Beta = -0.08, P < 0.09); however, it acted as a significant mediator, reducing the strength of the relationship between depressive symptoms and sleep quality and stress.

Conclusions
According to our study, a large proportion of healthcare (medical and dental) students were found to be suffering from mild to moderate depression and experienced poor sleep quality. It is concluded that social support is an important variable in predicting depressive symptomatology by ameliorating the effects of poor sleep quality and high stress levels.
Korupsi, Indikator Makro Ekonomi, dan IPM terhadap Tingkat Kemiskinan di Indonesia
Authors: Samputra Palupi Lindiasari , Munandar Adis Imam 
Published: October 2019

Penelitian ini bertujuan untuk mengetahui factor-faktor penyebab tingkat kemiskinan di Indonesia, baik dampak positif maupun negative. Terdapat tiga indicator utama yang digunakan untuk melihat seberapa besar dampak masing-masing indikator terhadap tingkat kemiskinan di Indonesia. Ketiga indikator tersebut di wakili oleh variable-variabel ; IPM (Indeks Pembangunan Manusia), Korupsi (jumlah terpidana kasus korupsi) dan indicator makroekonomi (inflasi, PDRB per kapita, jumlah penduduk (sebagai variable control)).
Metode penelitian yang digunakan adalah metode panel data, yang terdiri dari data tahun (2009-2013) dan data propinsi di Indonesia (28 propinsi). Model kemiskinan di Indonesia dapat dijelaskan melalui model Fixed Effect GLS setelah melalui uji pemilihan model terbaik dan uji pelanggaran asumsi klasik.
Hasil penelitian menunjukkan bahwa dari tiga indikator penyebab tingkat kemiskinan di Indonesia, hanya variable PDRB per kapita secara statistik tidak signifikan pengaruhnya terhadap tingkat kemiskinan. Factor-faktor lainnya dapat menjelaskan pengaruhnya terhadap tingkat kemiskinan secara signifikan. Terdapat dua pengaruh, yakni positif dan negative. Factor yang mampu menurunkan tingkat kemiskinan di propinsi-propinsi Indonesia adalah IPM (semakin besar pengaruhnya di propinsi luar Sumatera dan Jawa-Bali), inflasi dan jumlah penduduk. Hanya variable korupsi yang berdampak positif terhadap meningkatnya tingkat kemiskinan di Indonesia. Perlu peran aktif pemerintah dalam mewujudkan program pengentasan kemiskinan melalui pembangunan manusia di seluruh propinsi Indonesia.
Analysis of the melt spreading and MCCI during the ex-vessel phase of a severe accident in WWER-1000
Authors: Rijova N. , Saraeva V. , Gantchev K. , Bakalov I. , Wolff H. , Arndt S. 
Published: October 2019

Abstract
The paper presents analysis results of melt spreading and core-concrete interactions in the containment of a WWER-1000 plant during the ex-vessel phase of a severe accident. The failure of the vessel takes place 8 h 35 min after the initiation of the accident. It has been assumed that the whole area of the containment floor is available for spreading, i.e. the door between the reactor cavity and the main part of the containment is not locked. The melt flow rate from the reactor pressure vessel was used as a boundary condition. The simulation of the melt spreading was performed with the LAVA code. The calculated spreading area varies from 60 to 100 m2 depending on the assumed values of the melt properties. The results from the LAVA calculations were used in parallel for COCOSYS and MELCOR calculations to study the core-concrete interactions. From the analyses it turned out: a larger spreading area leads to a faster cooling of the melt in the initial period of the accident, but in the long term the temperatures are the same. 60 h after start of the ex-vessel phase, the melt is not stabilised.
Foreign language professional communicative competence as an essential condition of marine transport engineers training and their employment
Authors: Drazhan R. V. , Pazonova A. S. , Gluhih E. S. 
Published: October 2019

This article is devoted to the issues of foreign language training of future marine transport engineers and the topicality of their possession of foreign language professional communicative competence at the level needed to resolve professional problems in the process of employment. This work proves the necessity of improving the quality of foreign language training by means of additional educational programs and advanced courses on Marine, Business, Professional English, the purpose of which is to apply oral and written communicative skills in situations of business and professional communication in arranging and carrying out an international transportation, operation and management of water transport, as well as forwarding and agency services for ships. Following a competencybased approach, the goals, objectives and results of the development of programs of additional and professional foreign language education are clearly defined in accordance with the requirements of international, professional and educational standards and the results of training are given on examples of specific courses. The research results presented in the article can be used in development and implementation into the educational process the professional foreign language communication programs using e-learning and distance learning educational technologies. The authors emphasize the importance of social partnership with the employer in order to continuously monitor his requests and requirements for the graduate.
On the issue of the revitalization and modernization of the engineering in Russia
Authors: Melnikov A. E. 
Published: October 2019

Currently, one of the important tasks of the economic policy of Russia is the formation of a hightech image of the national economy, capable of effective functioning in the changing global geopolitical and geoeconomic conditions. In this context, the issue of revitalization of mechanical engineering, which plays a key role in the development of the country’s economy, is of particular relevance. This sector is a link between scientific and technological progress and the level of provision of domestic producers with domestic machines and equipment, allowing them to produce competitive products and to a lesser extent depend on the state of the external environment. The example of the developed countries of the world shows that the development of advanced engineering technology significantly increases the efficiency of the national economy, helps to accelerate its growth. At the same time, in Russia, in order to unleash the scientific and technical potential and activate engineering, it is necessary to initiate modernization processes in it. Based on the foregoing, the purpose of the study is to analyze the state of Russian engineering from the position of its role in the country’s economy. It is shown that at present a significant barrier to the development of this sector is the predominance of imported equipment, due to technical and operational characteristics, often superior to domestic counterparts.