bluuebunny/crossref_metadata_2025_split huggingface dataset:
The niches of nuthatches affect their lineage evolution differently across latitude
Authors: Chen Yu‐Chi , Nazarizadeh Masoud , Lei Fu‐Min , Yang Xiao‐Jun , Yao Cheng‐Te , Dong Feng , Dong Lu , Zou Fa‐Sheng , Drovetski Sergei V. , Liu Yang , Huang Chun‐Cheng , Hung Chih‐Ming 
Published: December 2018

AbstractEcological niche evolution can promote or hinder the differentiation of taxa and determine their distribution. Niche‐mediated evolution may differ among climatic regimes, and thus, species that occur across a wide latitudinal range offer a chance to test these heterogeneous evolutionary processes. In this study, we examine (a) how many lineages have evolved across the continent‐wide range of the Eurasian nuthatch (Sitta europaea), (b) whether the lineages’ niches are significantly divergent or conserved and (c) how their niche evolution explains their geographic distribution. Phylogenetic reconstruction and ecological niche models (ENMs) showed that the Eurasian nuthatch contained six parapatric lineages that diverged within 2 Myr and did not share identical climatic niches. However, the niche discrepancy between these distinct lineages was relatively conserved compared with the environmental differences between their ranges and thus was unlikely to drive lineage divergence. The ENMs of southern lineages tended to cross‐predict with their neighbouring lineages whereas those of northern lineages generally matched with their abutting ranges. The coalescence‐based analyses revealed more stable populations for the southern lineages than the northern ones during the last glaciation cycle. In contrast to the overlapping ENMs, the smaller parapatric distribution suggests that the southern lineages might have experienced competitive exclusion to prevent them from becoming sympatric. On the other hand, the northern lineages have expanded their ranges and their current abutting distribution might have resulted from lineages adapting to different climatic conditions in allopatry. This study suggests that niche evolution may affect lineage distribution in different ways across latitude.
Insecticide resistance status of three vectors of Japanese encephalitis in east central India
Authors: Sahu S. S. , Sonia T. , Dash S. , Gunasekaran K. , Jambulingam P. 
Published: December 2018

AbstractJapanese encephalitis (JE) has been reported in different districts of Odisha state (east central India) since 1992. During 2016, a major outbreak of JE and acute encephalitis syndrome (AES) occurred in the Malkangiri district of Odisha, causing 103 deaths in children, of which 37 were caused by JE and 66 by AES. Information on insecticide resistance in JE vectors is important for the selection of appropriate insecticides for use in vector control. The present study was designed to determine the resistance status of three important vectors of JE, Culex vishnui, Culex tritaeniorhynchus and Culex bitaeniorhynchus (Diptera: Culicidae), against dichlorodiphenyltrichloroethane (DDT), malathion and deltamethrin in three districts of Odisha state affected by JE. Female adult mosquitoes were collected using mouth aspirators both indoors and outdoors in JE‐affected villages and used in susceptibility bioassays following World Health Organization guidelines. Knock‐downs were recorded every 10 min up to 1 h and mortality rates were recorded at 24 h post‐exposure. Culex vishnui and Cx. tritaeniorhynchus showed resistance to DDT, malathion and deltamethrin, whereas Cx. bitaeniorhynchus was susceptible in all study districts. The information generated by this study will be highly useful in the planning and implementing of appropriate vector control operations for the prevention and control of JE in east central India.
Randomised clinical trial in women with Recurrent Vulvovaginal Candidiasis: Efficacy of probiotics and lactoferrin as maintenance treatment
Authors: Russo Rosario , Superti Fabiana , Karadja Eugen , De Seta Francesco 
Published: December 2018

SummaryBackgroundVulvovaginal candidiasis (VVC) is a recurrent vaginal condition in childbearing women.ObjectivesThe aim of this study was to assess the efficacy of an oral formulation containing Lactobacillus acidophilus GLA‐14, Lactobacillus rhamnosus HN001 and bovine lactoferrin on symptoms and recurrence of VVC as adjuvant therapy to topical clotrimazole.Patients/MethodsForty‐eight women positive for C. albicans, symptoms of VVC and documented history of recurrences were randomised into 2 groups receiving verum or placebo (2 capsules/day for 5 days followed by 1 capsule/day for additional 10 days) as adjuvant treatment to clotrimazole (induction phase) followed by a maintenance cycle of 6 months (1 capsule/day verum or placebo for 10 consecutive days each month). Symptoms, overall cure rate and recurrence rate were assessed.ResultsAfter clotrimazole therapy, a significant improvement of symptoms was shown in both groups. However, only women treated with probiotics and lactoferrin showed a significant improvement of itching and discharge at 3 and 6 months. During the six‐month follow‐up, recurrences were significantly less in the intervention group vs placebo (33.3% vs 91.7% after 3 months and 29.2% vs 100% after 6 months).ConclusionsThe results show that the investigated lactobacilli mixture in combination with lactoferrin represents a safe and effective adjuvant approach for reducing symptoms and recurrences of RVVC.
Fungal infections of the central nervous system and paranasal sinuses in onco‐haematologic patients. Epidemiological study reporting the diagnostic‐therapeutic approach and outcome in 89 cases
Authors: Candoni A. , Klimko N. , Busca A. , Di Blasi R. , Shadrivova O. , Cesaro S. , Zannier M. E. , Verga L. , Forghieri F. , Calore E. , Nadali G. , Simonetti E. , Muggeo P. , Quinto A.M. , Castagnola C. , Cellini M. , Del Principe M.I. , Fracchiolla N. , Melillo L. , Piedimonte M. , Zama D. , Farina F. , Giusti D. , Mosna F. , Capelli D. , Delia M. , Picardi M. , Decembrino N. , Perruccio K. , Vallero S. , Aversa F. , Fanin R. , Pagano L. ,   SEIFEM Group (Epidemiological Surveillance of Infections in Haematological Diseases)
Published: December 2018

SummaryInvasive fungal infections (IFI) of the Central Nervous System (IFI‐CNS) and Paranasal Sinuses (IFI‐PS) are rare, life‐threatening infections in haematologic patients, and their management remains a challenge despite the availability of new diagnostic techniques and novel antifungal agents. In addition, analyses of large cohorts of patients focusing on these rare IFI are still lacking. Between January 2010 and December 2016, 89 consecutive cases of Proven (53) or Probable (36) IFI‐CNS (71/89) and IFI‐PS (18/89) were collected in 34 haematological centres. The median age was 40 years (range 5‐79); acute leukaemia was the most common underlying disease (69%) and 29% of cases received a previous allogeneic stem cell transplant. Aspergillus spp. were the most common pathogens (69%), followed by mucormycetes (22%), Cryptococcus spp. (4%) and Fusarium spp. (2%). The lung was the primary focus of fungal infection (48% of cases). The nervous system biopsy was performed in 10% of IFI‐CNS, and a sinus biopsy was performed in 56% of IFI‐PS (P = 0.03). The Galactomannan test on cerebrospinal fluid has been performed in 42% of IFI‐CNS (30/71), and it was positive in 67%. Eighty‐four pts received a first‐line antifungal therapy with Amphotericine B in 58% of cases, Voriconazole in 31% and both in 11%. Moreover, 58% of patients received 2 or more lines of therapy and 38% were treated with a combination of 2 or more antifungal drugs. The median duration of antifungal therapy was 60 days (range 5‐835). A surgical intervention was performed in 26% of cases but only 10% of IFI‐CNS underwent neurosurgical intervention. The overall response rate to antifungal therapy (complete or partial response) was 57%, and 1‐year overall survival was 32% without significant differences between IFI‐CNS and IFI‐PS. The overall mortality was 69% but the IFI attributable mortality was 33%. Mortality of IFI‐CNS/PS remains high but, compared to previous historical data, it seems to be reduced probably due to the availability of newer antifungal drugs. The results arising from this large contemporary cohort of cases may allow a more effective diagnostic and therapeutic management of these very rare IFI complications in haematologic patients.
Treatment consensus for management of polymyositis and dermatomyositis among rheumatologists, neurologists and dermatologists
Authors: Kohsaka Hitoshi , Mimori Tsuneyo , Kanda Takashi , Shimizu Jun , Sunada Yoshihide , Fujimoto Manabu , Kawaguchi Yasushi , Jinnin Masatoshi , Muro Yoshinao , Ishihara Shoichiro , Tomimitsu Hiroyuki , Ohta Akiko , Sumida Takayuki 
Published: December 2018

AbstractAlthough rheumatologists, neurologists, and dermatologists see patients with polymyositis (PM) and dermatomyositis (DM), their management appears to vary depending on the physician's specialty. The aim of this study was to establish the treatment consensus among specialists of the three fields to standardize the patient care. We formed a research team supported by a grant from the Ministry of Health, Labor, and Welfare, Japan. Clinical questions (CQ) on the management of PM and DM were raised. A published work search on CQ was performed primarily using PubMed. Using the nominal group technique, qualified studies and results in the published work were evaluated and discussed to reach consensus recommendations. They were sent out to the Japan College of Rheumatology, Japanese Society of Neurology, and Japanese Dermatological Association for their approval. We reached a consensus in 23 CQ and made recommendations, and a decision tree for management was proposed. They were officially approved by the three scientific societies. In conclusion, a multidisciplinary treatment consensus for the management of PM and DM was established for the first time.
Advocacy care on HIV disclosure to children
Authors: de Moura Bubadué Renata , Cabral Ivone Evangelista 
Published: December 2018

AbstractChildren with HIV are dependent on taking continuous medication and care, and family preparation is required when disclosing HIV. This study aimed to unveil families’ experiences with HIV disclosure to children under 13 years old. Eight family members who have disclosed HIV to seropositive children were interviewed in‐depth and individually. The fieldwork took place at a public paediatric outpatient hospital in Rio de Janeiro. The results showed that the family members’ discourse highlighted two ways of knowing their own condition and disclosing the condition of the children with HIV. First, they needed to address the communication of bad news and discover their own HIV status through their children's disease. Second, the disclosure was a process constituted by four stages: preparing for disclosure, identifying the time, deciding how and where to tell, and instilling silence after disclosure. They also recognized that nurses had a role in the process as part of an interprofessional team. Nurses can develop advocacy care and empower family members in the preparation of safe HIV disclosure. By systematizing and institutionalizing the care advocacy process, nurses may enable caretakers and children to participate in their therapeutic management, improving adherence to the treatment and self‐care with autonomy.
Annotated checklist of Senegalia and Vachellia (Fabaceae: Mimosoideae) for the Indian subcontinent
Authors: Deshpande Anup S. , Krishnan Sellappan , Janarthanam Malapati K. , Maslin Bruce R. 
Published: December 2018

An annotated checklist of Senegalia Raf. and Vachellia Wight & Arn. taxa for the Indian subcontinent is presented, following the fragmentation and retypification of the former broadly defined genus Acacia Mill. The countries encompassed by this study include Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan and Sri Lanka. All indigenous species (and a few introductions) in this region previously referred to Acacia belong to Senegalia and Vachellia. All Acacia s.s. taxa are introduced (principally from Australia) and are not included in the study. There are 22 species of Senegalia (21 indigenous, 1 introduced; representing 23 taxa) and 21 species of Vachellia (12 indigenous, 9 introduced; representing 27 taxa) currently recognized for the subcontinent. The largest country, India, has most species. This checklist complements that which was recently provided for these genera in southeast Asia and China.Two names formerly recorded for the Indian subcontinent are excluded, namely, Senegalia intsia (L.) Maslin is a nomen confusum and Acacia pennata subsp. hainanensis (Hayata) I. C. Nielsen is now known to be restricted to southern China and Vietnam. Acacia eriantha Desv. is an unresolved name.The following new combinations are made herein: Senegalia tanjorensis (Ragup., Thoth. & A.Mahad.) A.S.Deshpande & Maslin, Vachellia campbellii (Arn.) A.S.Deshp., & Maslin and V. pseudowightii (Thoth.) A.S.Deshpande & Maslin.A lectotype has been selected for Acacia pennata var. canescens Graham ex Kurz (= Senegalia pennata (L.) Maslin).
Multifunctional nanocarriers for the treatment of periodontitis: Immunomodulatory, antimicrobial, and regenerative strategies
Authors: Cafferata Emilio A. , Alvarez Carla , Diaz Karla T. , Maureira Miguel , Monasterio Gustavo , González Fermín E. , Covarrubias Cristian , Vernal Rolando 
Published: December 2018

AbstractPeriodontitis is an inflammatory disease, in which the host immuno‐inflammatory response against the dysbiotic subgingival biofilm leads to the breakdown of periodontal tissues. Most of the available treatments seem to be effective in the short‐term; nevertheless, permanent periodical controls and patient compliance compromise long‐term success. Different strategies have been proposed for the modulation of the host immune response as potential therapeutic tools to take a better care of most susceptible periodontitis patients, such as drug local delivery approaches. Though, maintaining an effective drug concentration for a prolonged period of time has not been achieved yet. In this context, advanced drug delivery strategies using biodegradable nanocarriers have been proposed to avoid toxicity and frequency‐related problems of treatment. The versatility of distinct nanocarriers allows the improvement of their loading and release capabilities and could be potentially used for microbiological control, periodontal regeneration, and/or immunomodulation. In the present review, we revise and discuss the most frequent biodegradable nanocarrier strategies proposed for the treatment of periodontitis, including polylactic‐co‐glycolic acid (PLGA), chitosan, and silica‐derived nanoparticles, and further suggest novel therapeutic strategies.
Pediatric oncologic emergencies: Clinical and imaging review for pediatricians
Authors: Handa Atsuhiko , Nozaki Taiki , Makidono Akari , Okabe Tetsuhiko , Morita Yuka , Fujita Kazutoshi , Matsusako Masaki , Kono Tatsuo , Kurihara Yasuyuki , Hasegawa Daisuke , Kumamoto Tadashi , Ogawa Chitose , Yuza Yuki , Manabe Atsushi 
Published: December 2018

AbstractChildren with cancer are at increased risk of life‐threatening emergencies, either from the cancer itself or related to the cancer treatment. These conditions need to be assessed and treated as early as possible to minimize morbidity and mortality. Cardiothoracic emergencies encompass a variety of pathologies, including pericardial effusion and cardiac tamponade, massive hemoptysis, superior vena cava syndrome, pulmonary embolism, and pneumonia. Abdominal emergencies include bowel obstruction, intussusception, perforation, tumor rupture, intestinal graft‐versus‐host disease, acute pancreatitis, neutropenic colitis, and obstructive uropathy. Radiology plays a vital role in the diagnosis of these emergencies. We here review the clinical features and imaging in pediatric patients with oncologic emergencies, including a review of recently published studies. Key radiological images are presented to highlight the radiological approach to diagnosis. Pediatricians, pediatric surgeons, and pediatric radiologists need to work together to arrive at the correct diagnosis and to ensure prompt and appropriate treatment strategies.
International law and political philosophy: Uncovering new linkages
Authors: Ratner Steven 
Published: December 2018

AbstractDespite a common agenda of normative analysis of the international order, philosophical work on international political morality and international law and legal scholarship have, until recently, worked at a distance from one another. The mutual suspicion can be traced to different aims and methodologies, including a divide between work on matters of deep structure, on the one hand, and practical institutional analysis and prescription, on the other. Yet international law is a key part of the normative practices of states, has a direct effect on state behavior, and, as a methodological matter, can contribute to good theorizing on matters of international ethics. Recently, philosophical work has demonstrated a greater engagement with the moral aspects of international law. One strand of scholarship has treated the rules of international law as a proper subject for philosophical inquiry. Another has used international legal rules to support moral arguments about aspects of the international order. Future dialogue and cooperation would benefit both fields, in particular on the challenges to global cooperation from nationalism and on strategies for allocating responsibilities among global actors for rectifying global harms.
International reflections on caring for people with advanced dementia
Authors: Yumoto Yoshie , Kernohan W. George , Morioka Noriko , Ogata Yasuko 
Published: December 2018

AbstractDementia is causing global concern with its massive impacts on affected individuals, families, society, and national economies. As the disease progresses, patients’ needs increase in number, depth, and breadth, covering physical, psychological, social, and spiritual domains. Care varies from place to place, from country to country and from east to west. To learn from some of these variations, we explored advanced dementia care in United Kingdom and Japan. Informed by an overview of literature on care of people with advanced dementia, we reflected on direct nonparticipant observations of care in urban areas of Northern Ireland and Japan. While we identified a common purpose to address the complex needs of people living with dementia, there were differences in the approach to care. Broadly, dementia care in United Kingdom tends toward person‐centered care with a strong interest in Advance Care Planning as part of a palliative care approach. In Japan, we found less evidence of early stage palliative care and more of family‐based decision making to inform care of older people. In both countries, dementia care varies regionally, being more available in some areas than others. International knowledge exchange and further comparative studies will help to improve care for people with advanced dementia, everywhere.
The invasive green alga Avrainvillea sp. transforms native epifauna and algal communities on a tropical hard substrate reef
Authors: Foster Alexa D. , Spalding Heather L. , Cox T. Erin , La Valle Florybeth F. , Philippoff Joanna 
Published: December 2018

SUMMARYSome introduced species compete directly with native species for resources and their spread can alter communities, while others do not proliferate and remain benign. This study compares community structure and diversity in adjacent areas dominated by the introduced alga Avrainvillea sp. or native algal species on a hard substrate reef. The biomass and species composition of 15 paired plots (30 in total, plot type based on dominance of Avrainvillea sp. or native species) were quantified. Plots dominated by Avrainvillea sp. had a significantly different assemblage of species characterized by lower algal diversity, mostly Dictyota spp. and Laurencia sp., and a higher abundance and diversity of invertebrates, such as small arthropods, polychaetes, and brittlestars. These results suggest that as Avrainvillea sp. becomes more abundant on hard substrate reefs, it will engineer a different community composed of algal epiphytes and an invertebrate assemblage more typically associated with algae in soft sediments.
Applications of microalga Chlorella vulgaris in aquaculture
Authors: Ahmad Muhammad Talba , Shariff Mohamed , Md. Yusoff Fatimah , Goh Yong Meng , Banerjee Sanjoy 
Published: December 2018

AbstractMicroalgae biomass is used in aquaculture as feed, growth enhancers and immunostimulants. Chlorella vulgaris is an important species with a good biomolecular composition. Commercially, it is one of the most commonly used microalga in aquaculture. Several studies confirmed its ability to improve nutrition, immunity, aquatic bioremediation, amelioration of stress, disease resistance of fish and inhibits bacterial quorum sensing when used appropriately. Despite claims of its benefits, C. vulgaris is reported to have unfavourable effects when incorporated in diets at higher inclusion levels. In addition, its rigid cell wall might restrict the access of digestive enzymes to the intracellular components for proper digestion and assimilation. Thus, this review discusses the role of C. vulgaris and its importance in aquaculture with emphasis on its environmental requirements, morphology, pigments, digestibility, dynamics on growth performance, antibacterial activity, bacterial quorum sensing, immunomodulatory effect, anti‐stress effect, gut microbiome, aquatic bioremediation and its safety as food or feed.
The health consequences of hazardous and nonhazardous child labor
Authors: Posso Alberto 
Published: December 2018

AbstractThe health consequences of child labor are ambiguous. On the one hand, heavy lifting, using dangerous tools and handling fertilizers may impact negatively on health. On the other, child labor could be used to achieve a minimal subsistence standard, without which the child could experience deteriorating health. Previous empirical studies are inconclusive because, until now, existing data sources could not disentangle between different activities performed by child workers. To establish how work is related to health, it is essential to know what activities are being performed. This study fills this gap with a unique child labor survey conducted in Peru in 2015. Child labor is classified into hazardous and nonhazardous activities. The econometric results suggest that children doing nonhazardous work are less likely to have health problems than nonworking children. Conversely, those that work in hazardous activities are potentially more likely to exhibit health concerns. A series of robustness tests confirm these findings. The results give impetus to the notion that child work increases total resources available for households, which can improve child health. Therefore, it is over and above this potential increment in resources that some hazardous activities worsen working children's health.
Microfinance and income inequality: New macrolevel evidence
Authors: Lacalle‐Calderon Maricruz , Larrú José Maria , Garrido Silvia Rico , Perez‐Trujillo Manuel 
Published: December 2018

AbstractThis paper addresses the empirical question of whether microfinance has any impact on income inequality at the macrolevel. Very little research has been conducted on the relationship between the macrolevel scale of microfinance and income inequality over time in a country and across countries. Based on panel‐data techniques, with annual data from 85 countries from 2001 to 2012 and a broad theoretical framework on microfinance and inequality, we provide empirical evidence that suggests that increases in the macrolevel scale of microcredit in a country contribute to reducing income inequality within that country over time. Finally, since microfinance may be endogenous, we used instruments from the existing literature to control for this problem.