bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oxygenation Responses While Wearing the Elevation Training Mask During an Incremental Cycling Test
Authors: Romero-Arenas Salvador , López-Pérez Emilia , Colomer-Poveda David , Márquez Gonzalo 
Published: February 2019

Abstract
Romero-Arenas, S, López-Pérez, E, Colomer-Poveda, D, and Márquez, G. Oxygenation responses while wearing the elevation training mask during an incremental cycling test. J Strength Cond Res 35(7): 1897–1904, 2021—The Elevation Training Mask 2.0 (ETM) is a commercial training mask that purportedly simulates altitude training, although their effects have not been conclusively demonstrated. Therefore, the purpose of this study was to evaluate the influence of wearing the ETM on muscle and brain oxygenation responses during a maximal incremental cycling test, as well as the influence of this device on the heart rate (HR) response, perception of effort (rating of perceived exertion [RPE]), arterial oxygen saturation (SaO2), blood lactate (La+), and performance (POpeak). Fourteen active males completed an incremental cycling test to volitional exhaustion in 2 separate and counterbalanced conditions, wearing the mask set at 9,000 feet (i.e., 2743 m) and a control condition (CTR, without ETM). During the trial, muscle and cerebral oxygenation were monitored continuously using near-infrared spectroscopy. Heart rate, RPE, and SaO2 were also recorded from the beginning of the test until the volitional exhaustion. La+ was measured at the end of each test. Wearing the ETM significantly reduced the POpeak by −6.9 ± 6.6% (p = 0.002) and this was accompanied by lower La+ values (−12.8 ± 21.6%; p = 0.027). SaO2 was also significantly lower at maximal intensity in comparison with the CTR condition (−1.5 ± 0.3%; p = 0.028). However, both HR and RPE showed a similar trend during both sessions, as well as muscle oxygenation. Nevertheless, the mask caused an increase in brain oxygenation compared with the CTR condition (p < 0.05). In conclusion, our findings suggest that wearing the ETM causes a pronounced increase in O2Hb and tHb in the frontoparietal cortex without any change in the muscle oxygenation.
A Longitudinal Study of Identifying Critical Variables Influencing Patient Safety Culture from Nurses’ Viewpoints in Taiwan
Authors: Lee Yii-Ching , Huang Chih-Hsuan , Wu Cheng-Feng , Hsueh Hsiu-Wen , Wu Hsin-Hung 
Published: February 2019

Abstract
This study uses longitudinal data from a regional teaching hospital in Taiwan to analyze how nurses with different demographic variables perceive patient safety culture from 2010 to 2016. The results show that nurses with different demographic variables have different perceptions of patient safety from year to year. The supervisor/manager is the most essential variable influencing patient safety culture. Nurses who are supervisors/managers are more satisfied in six dimensions from 2010 to 2016. Experience in an organization is identified as the second essential variable to influence the patient safety culture. Nurses who have much experience in an organization tend to have higher satisfaction in five out of six dimensions of patient safety culture from 2012 to 2016 in general. In contrast, nurses who have less than six months of experience in an organization also have better perceptions. In summary, hospital management needs to pay attention to supervisor/manager and experience in an organization factors, both of which have significant impacts on patient safety culture from nurses’ viewpoints.
Microscopic Characteristics of Field Compaction of Asphalt Mixture Using Discrete Element Method
Authors: Liu Weidong , Gong Xing , Gao Ying , Li Limin 
Published: February 2019

Abstract
To investigate microscopic characteristics of the field compaction of asphalt pavement, a three-dimensional (3D) compaction model of asphalt pavement considering morphological characteristics of aggregate and temperature effect was established by distributed load and time equivalence principles using Particle Flow Code in Three Dimensions (PFC3D). The microscopic parameters of hot asphalt mixture were determined with a dynamic modulus test based on the time–temperature superposition principle. Aggregate motion, contact force, and the evolutional mechanism of energy were monitored during the virtual compaction process. This indicated that the motion displacement, angle, and stress are positively associated with load direction. It is necessary to select the proper plane angle with the load direction to evaluate the 3D motion of the aggregate with the two-dimensional (2D) plane angle. During the compaction process, the contact compressive force is mainly produced between aggregates, and the evolution laws of contact force and stress tensor can be used to reasonably interpret the aggregate motion within the asphalt mixture. Additionally, the work of external force, kinetic energy, and strain energy can be employed to precisely demonstrate energy conversion for the developed compaction model. Indexes including motion displacement and angle, contact force, and energy can reflect the microscopic characteristics of asphalt mixture during field compaction. It is rational and feasible to analyze microscopic behavior of asphalt pavement with the proposed pavement compaction model using the discrete element method (DEM). The DEM is a significant tool of investigation of microscopic characteristics of asphalt pavement.
Fast Estimation of Recombination Rates Using Topological Data Analysis
Authors: Humphreys Devon P , McGuirl Melissa R , Miyagi Miriam , Blumberg Andrew J 
Published: February 2019

Abstract
Accurate estimation of recombination rates is critical for studying the origins and maintenance of genetic diversity. Because the inference of recombination rates under a full evolutionary model is computationally expensive, we developed an alternative approach using topological data analysis (TDA) on genome sequences. We find that this method can analyze datasets larger than what can be handled by any existing recombination inference software, and has accuracy comparable to commonly used model-based methods with significantly less processing time. Previous TDA methods used information contained solely in the first Betti number (β1) of a set of genomes, which aims to capture the number of loops that can be detected within a genealogy. These explorations have proven difficult to connect to the theory of the underlying biological process of recombination, and, consequently, have unpredictable behavior under perturbations of the data. We introduce a new topological feature, which we call ψ, with a natural connection to coalescent models, and present novel arguments relating β1 to population genetic models. Using simulations, we show that ψ and β1 are differentially affected by missing data, and package our approach as TREE (Topological Recombination Estimator). TREE’s efficiency and accuracy make it well suited as a first-pass estimator of recombination rate heterogeneity or hotspots throughout the genome. Our work empirically and theoretically justifies the use of topological statistics as summaries of genome sequences and describes a new, unintuitive relationship between topological features of the distribution of sequence data and the footprint of recombination on genomes.
Fecalitos: valor diagnóstico de este hallazgo en pacientes sin clínica de abdomen agudo
Authors: Ramírez Chacón Jorge Luis , Alvarado Dávila Pablo 
Published: February 2019

Resumen: Apendicitis aguda, un cuadro clínico inflamatorio del apéndice cecal, cuyo punto fisiopatológico inicial es la obstrucción luminal del apéndice, es uno de los diagnósticos más frecuentemente encontrados en el servicio de emergencias, más su diagnóstico clínico en pacientes con condiciones especiales no siempre es tan sencillo. A continuación presentamos el caso de una paciente de 76 años de edad, con una historia de dolor abdominal periumbilical de 24 horas de evolución, sin hallazgos sugestivos de apendicitis aguda en su evaluación clínica inicial, la cual presentó hallazgos radiológicos poco usuales.
Actividad HEMORR2HAGES, ATRIA Y HAS-BLED para la estimación de eventos hemorrágicos en pacientes latinoamericanos con fibrilación atrial que requieren anticoagulación.
Authors: Chaverri Fernández José Miguel , Díaz Madriz José Pablo , Cordero García Eugenia , Hernández Herrera Luis , Perera Quesada Valeria , Zavaleta Monestel Esteban 
Published: February 2019

Objetivo: comparar y conocer la eficacia predictiva del riesgo de sangrados en pacientes hospitalizados con diagnóstico de fibrilación atrial que requieren anticoagulación en forma crónica, con el uso de las herramientas disponibles internacionalmente (HEMORR2HAGES, HAS-BLED Y ATRIA). Resultados: Se realizó un estudio observacional de tipo retrospectivo que incluyó a 97 pacientes diagnosticados con fibrilación atrial y tratados con anticoagulantes orales entre enero 2014 y marzo 2016. Tomando los datos sin categorizar, se demuestra que el modelo utilizado en el estudio ha clasificado correctamente a un 60,8% de los casos totales prediciendo correctamente la posibilidad de sangrado, Al tomar en cuenta las herramientas o variables independientes el valor de predicción aumenta en un 10%, lo cual indica que las herramientas van a ser efectivas en la predicción en un 70% de los casos. Conclusiones: A pesar de que al comparar las herramientas utilizadas en la predicción de eventos asociados a sangrados no se logró demostrar un ajuste significativo de los datos obtenidos con el modelo estadístico propuesto, podemos decir que HEMORR2HAGES es la herramienta que podría sugerir una mejor predicción de sangrado según la realidad observada en el Hospital Clínica Bíblica.
Methylene blue degradation under visible irradiation on TiO2 electrodes sensitized by dye chlorophyll extract from Spinacia Olera/Degradación de azul de metileno bajo irradiación visible sobre electrodos de TiO2 sensibilizados con pigmentos de clorofila..
Authors: Vallejo William Andres , Diaz Carlos , Alvis Maria , Cantillo Alvaro , Fajardo Catalina 
Published: February 2019

En este trabajo se evaluó la actividad fotocatalítica de pigmentos fotosintéticos (clorofila), adsorbidos sobre superficie de dióxido de titanio en presencia de luz visible, los pigmentos fueron extraídos por maceración en frío, a partir de plantas de espinaca (Spinacia Olerace), la fabricación de las películas de TiO2 fue realizada utilizando la técnica de Doctor Blade, la cuantificación de los pigmentos se realizó mediante el método tricromático según la norma estandarizada para la cuantificación de clorofila 10200 H. Los pigmentos fijados sobre la superficie de TiO2 aumentaron la respuesta de este material en el rango visible, finalmente se evaluó la capacidad fotocatalítica del TiO2 modificado bajo irradiación visible, la degradación del azul de metileno se evaluó durante 140 minutos, obteniendo un porcentaje de degradación de los electrodos modificados fue superior al de los electrodos de TIO2 sin modificar.
Trend analysis of research results in biodiesel production from 2009 to 2016/Análisis de tendencia de la los resultados de investigación en producción de biodiésel de 2009 a 2016
Authors: Meriño Stand Lourdes Isabel , Valencia Guillermo Eliecer , Benavides Aldair Enrique 
Published: February 2019

El presente estudio se realizó con el fin de evaluar la producción mundial científica relacionado a la producción del combustible biodiésel tomando bases e información de los años abarcados entre 2009 – 2016. Los resultados de las publicaciones, revistas, categorías de los temas, instituciones fueron analizados para hallar la producción investigativa mundial del biodiésel. Además, se aplicó el “análisis de conglomerados de palabras” (Word cluster analysis) para mostrar una visión sobre las tendencias acerca de la fabricación y producción del biodiésel. Los resultados indican que las publicaciones anuales sobre la producción biodiésel se fue incrementando a partir del año 2009 y con un avance significativo de casi el doble entre los años 2010 y 2011. China y Malasia con 3 instituciones a nivel mundial están en el top 10 de instituciones contribuyente con relación a la producción de biodiésel en los últimos años. Cada día se estudia con mayor frecuencia la producción de biodiésel, en todo tipo de seres vivo incluso hasta en el procesamiento de alimentos [1] , especialmente en las micro algas, debido a que poseen la capacidad de mitigar emisiones de y producir lípidos, por lo que se consideran con potencial para la obtención de biocombustibles de tercera generación [2], aunque diversos autores coinciden en que el comportamiento de las micro algas difieren según entorno y condiciones.
TOTAL DİZ ARTROPLASTİSİNDE KORKU VE ANKSİYETENİN YAŞAM KALİTE VE İŞLEVSEL SONUÇLARA ETKİSİ
Authors: AŞCI Murat 
Published: February 2019

Amaç: Diz artroplastisi yapılan hastalarda yaklaşık olarak 1/5 oranında memnuniyetsizlik görülmektedir. Kötü sonuçlarla ilişkili olan değişkenler ağrının şiddeti ve kronikliği, fizyolojik hastalıklar, kötü başa çıkma stratejileri ve ağrının dayanılmaz şiddette olmasıdır. Fizyolojik hastalıklar anksiyete ve depresyon şeklinde semptom gösterebilir. Ne anksiyetenin ne de depresyonun diz artroplastisi uygulaması öncesinde yapısal mı yoksa diz ağrısının bir sonucu mu olduğu açık değildir. Total diz artroplastisi günümüzde sıklıkla uygulanan büyük bir cerrahi haline gelmiştir. Genellikle yaşlı hastalara uygulanan bu cerrahiye veya hastalığa bağlı hastalarda korku ve anksiyete gelişebilmektedir. Bu çalışmada total diz artroplastisi yapılan hastaların ameliyat öncesindeki korku ve anksiyete durumlarının ameliyat sonrası yaşam kalitesi ve işlevsel sonuçlarına etkisi araştırıldı.Yöntem: 2003-2011 yılları arasında 217 hastaya uygulanan total diz artroplastisi ameliyatından ulaşılan 112 hasta retrospektif olarak Pain Anxiety Symptom Score(PASS), WOMAC ve SF-36(Short Form-36) skorlama sistemleri ile değerlendirildi. 112 hastanın (ort. yaş: 71,7, 86 kadın, 26 erkek) ameliyat öncesi dönemdeki korku ve anksiyete durumları PASS skorlama sistemi ile elde edildi. Ameliyat öncesi ve ameliyat sonrası yaşam kalitesi ve işlevsel durumları ise WOMAC ve SF-36 ile elde edildi. PASS skoru için sınır değer 100 alındı ve hastalar 2 gruba ayrıldı. Ameliyat öncesi ve ameliyat sonrası SF-36 skorları ve WOMAC skorları bu iki grup arasında karşılaştırıldı.Bulgular: PASS’a göre ayrılan her iki grupta ameliyat öncesine göre ameliyat sonrası dönemde SF-36’nın bütün parametrelerinde ve WOMAC skorlarında istatistiksel olarak anlamlı iyileşme saptandı. Anksiyete durumlarına göre WOMAC ve SF-36’daki değişim miktarları karşılaştırıldığında SF-36’nın sosyal işlev ve mental sağlık parametrelerindeki iyileşme miktarının farklı olduğu gözlendi. PASS skorları 100’ün üzerinde olan hasta grubunda (70 hasta) SF-36’nın sosyal işlev parametresindeki iyileşme miktarının daha fazla olduğu gözlendi. PASS skorları 100’ün altında olan hasta grubunda ise(42 hasta) SF- 36’nın mental sağlık parametresindeki iyileşme miktarının daha fazla olduğu gözlendi.Çıkarımlar: Total diz artroplastisi hastalarının yaşam kalitelerinde ve işlevsel durumlarında belirgin iyileşme sağlamaktadır. Hastaların ameliyat öncesi dönemdeki korku ve anksiyetesi total diz artroplastisinin işlevsel sonuclarına etki etmemektedir. Ancak SF-36’nın sosyal ve mental parametrelerini etkilediği görülmektedir.
Elastic, Electronic and Vibrational Properties of Ir-based Refractory Superalloys
Authors: AL Selgin , ARIKAN Nihat 
Published: February 2019

The
mechanical, electronic and vibrational properties of Ir-based refractory
superalloys (Ir3Hf and Ir3Nb) in the L12
structure were studied in the framework of ab initio calculations. The
obtained equilibrium lattice constants and bulk modulus were reported and
compared with the existing data. The elastic constants of alloys were determined
using energy strain method. The results were utilised to evaluate mechanical
stability of alloys in the crystal structure of L12. Both alloys were found to be mechanically
stable based on the Pugh’s criteria. Subsequently, electronic band structures
and partial and total densities of states have been obtained for Ir3Hf
and Ir3Nb. The band structures of alloys demonstrated metallic behaviour
whilst the conductivity was mostly governed by Ir 5d states. Moreover, phonon
distribution curves of both alloys were obtained by employing the linear
response technique within the density functional theory. Both alloys are found
to be dynamically stable based on phonon modes evaluation.
Isparta ve çevresinde klopidogrel direncinin araştırılması
Authors: AKSOY Fatih , BAŞ Hasan Aydın , BAĞCI Ali , UYSAL Bayram Ali , AKSOY Seda , VAROL Ercan , ALTINBAŞ Ahmet 
Published: February 2019

Giriş ve amaç: Akut koroner sendrom (AKS) ile başvuran ve/veya
stent uygulanan hastalarda klopidogrel tedavisi günümüzde standart tedavidir.
Bununla beraber klopidogrel tedavisine yanıtsızlık olumsuz sonuçlarla ilişkili
olması nedeni ile günümüzde önemli bir sorundur. Antitrombositer ilaçların
etkinliğini ölçmek için kullanılan trombosit fonksiyon testleri çoğu kez
pahalı, zaman alıcı ve ulaşılması zor testlerdir. Klopidogrel direncini
saptamak için pratik, kolay uygulanabilinir, ucuz ve güvenilir parametrelere
ihtiyaç vardır.

Materyal-Metot: Akut Koroner Sendrom tanısı ile klopidogrel
kullanan 531 hasta çalışmaya alındı. Alınan kan örneklerinde MEA (multiple
electrod aggregometry) ile çalışıldı. Sonuçlar eğri altında kalan alan (AUC)
cinsiden verildi. AUC &gt; 470 olması klopidogrel direci, olarak yorumlandı.

Bulgular: Toplamda
65 (% 12,2) hastada klopidogrel direnci saptandı. Kadın
hastalarda klopidogrel direnci anlamlı olarak fazlaydı (P= 0,005). Risk
faktörlerine bakıldığında ise hiperlipidemik ve diyabetik hastalarda
klopidogrel direnci daha fazla görülürken, sigara içenlerde direnç daha az
görülmekteydi (p= 0,016, p&lt; 0,001, p= 0,046). Klopidogrel direnci olan
hastalarda kalsiyum seviyesi, trombosit sayısı ve vücut kitle indeksi daha
yüksek bulundu.

Sonuç: Bu çalışma, vücut kitle indeksi, diyabet, hiperlipidemi,
kadın cinsiyet’in klopidogrel direnci açısından bir risk faktörü olabileceğini
ortaya koymuştur.
MARI, Tommaso. Pauca de barbarismo collecta de multis: studio ed edizione critica. Pisa: Edizioni ETS, 2017. 146 p.
Authors: Grein Everton 
Published: February 2019

Resenha: MARI, Tommaso. Pauca de barbarismo collecta de multis: studio ed edizione critica. Pisa: Edizioni ETS, 2017. 146 p.
Long-term change in health-related quality of life in patients with asthma
Authors: Perel’man N. L. , Kolosov V. P. 
Published: February 2019

The aim of this study was to investigate long-term change in health-related quality of life (HRQL) in patients with asthma in real clinical practice and in relation to emotional disorders, cooperativeness (cooperation between the patient and the physician, and adherence to treatment), and cold air-provoked bronchial hyperresponsiveness (BHR).Methods. This observational study involved 32 patients with mild to moderate asthma. The study duration was 7.5 to 10 years. HRQL was assessed using SF-36 questionnaire and Asthma Quality of Life Questionnaire (AQLQ); emotional disorders were diagnosed using Hospital Anxiety and Depression Scale (HADS). Patients’ cooperativeness assessment was based on number of a patient’s scheduled visits to a physician during the study. The asthma control level was evaluated using the Asthma Control Test (ACT).Results. A significant worsening was found in the social activity domain of HRQL in the total group of the patients. According to AQLQ, a significant improvement was seen in the activity and symptoms domains and in the total score of quality of life (QoL). Long-term pharmacological treatment of asthma decreased anxiety and depression levels. The asthma control (ACT score) increased from 13.2 ± 1.0 to 19.7 ± 1.1 (р = 0.00003). Anxiety and depression decreased in patients with high cooperativeness during the long-term follow-up, while the total QoL and the specific QoL were unchanged excluding the social activity domain. A significant worsening in the activity scale and in the emotional scale of specific QoL together with growing depression and decreasing control of asthma were found in patients with lower cooperativeness. The cold air-provoked BNR slowed down the long-term improvement in the social activity domain. The cold air-provoked BNR also decreased patient-reported evaluation of daily activity.Conclusion. The long-term basic therapy of asthma provides a positive trend in HRQL in the real clinical practice independently on worsening of the disease. Lower cooperativeness of a patient could decrease specific QoL, which, in turn, worsens the control of asthma and contributes to negative emotional background and destructive behavior.
METHODOLOGICAL APPROACHES TO DETERMINING THE STATE OF BLOCK SEISMOGENIC MEDIUM ON THE EXAMPLE OF THE 2008-2011 SEISMIC ACTIVATION IN THE CENTRAL PART OF THE BAIKAL RIFT
Authors: Dyadkov P. G. , Romanenko Y. M. , Kozlova M. P. , Tsibizov L. V. , Duchkova A. A. 
Published: February 2019

Based on the joint analysis of the seismic regime parameters, such as anomalies of seismic energy release, b-value, seismic activity A10, approaches to assess the state of the block-seismic medium are proposed. The method validation was done for the example of preparation and development of seismic activity in 2008-2011 in the Central part of the Baikal rift, during which there were 2 strong M5.3 earthquakes. It was found that within 2 years before the strong Maximihinskoye Earthquake of 2008 in the Earth's crust of the epicentral region there is a transformation from softening to strengthening (consolidation) of the block medium. At the same time, in the neighboring region (the area of the Svyatoy Nos Peninsula), the opposite nature of the changes is observed.
STRUCTURAL CHARACTERISTICS OF VENDIAN-CAMBRIAN SEDIMENTS WITHIN THE NORTHTUNGUSKA OGR USING SEISMIC 2D DATA IN CONNECTION WITH PETROLEUM POTENTIAL
Authors: Gubin I. A. , Taratenko A. V. 
Published: February 2019

Complex interpretation of seismic and parametric drilling data is performed. The data for interpretation are obtained within the conjunction zone of the Kureyka syncline and the Anabar anteclise. As a result of complex interpretation the structural maps on the bottom of Vendian and the top of the Kuonamka formation are constructed. Map of the Vendian terrigenous complex was constructed. High prospects of oil and gas potential of the lower-middle Cambrian sediments are shown. Based on the analysis of logging data, core description and detailed correlation of time sections, the litho-acoustic models were compiled for two profiles crossing the barrier-reef system, and two-dimensional synthetic time sections were calculated. Obtained results confirm the correctness of the ideas about the internal structure of the Vendian-Cambrian complexes.