bluuebunny/crossref_metadata_2025_split huggingface dataset:
Data Commentary in Research Publications: A Scoping Review
Authors: Tikhonova Elena , Raitskaya Lilia 
Published: November 2024

Introduction: The modality of scholarly written communication offers verbal and visual modes that are supposedly to be interrelated. The verbal component is thoroughly studied whereas the visual, including tables, charts, graphs and others are mainly described from a technical perspective. The editorial review aims to synthesize research on data commentary as a comparatively new rhetorical genre.
Method: The review adhered to the PRISMA extension for scoping reviews, and the PPC framework. The eligibility criteria include problem, concept, context, language, types of sources,
Results: The searches and consequent screening by titles, abstracts, keywords and full texts identified 19 relevant publications – articles and books – mainly indexed in the Scopus and SpringerLink databases. The books on academic writing focused on the three themes: general guidelines on data commentary, functions, and rhetorical structure of such commentaries, figure legends and notes to tables. The functional analysis of the publications singled out a prevailing framework, including rhetorical, ontological, epistemological, and argumentative functions. The rhetorical steps in data commentaries follow patterns suitable for the type of a visual. The review outlines generic steps described and proved by the research publications included in the review.
Conclusion: Though the research field is scattered, and no definite trends were specified, the potential of the field is rising as the implications of such studies are significant. A constant trend towards more visualization of the new knowledge requires more research on the interrelations between the verbal and the visual, with a special accent on data commentary.
From past to present, exploring the applications of mupirocin ointment: A comprehensive review
Authors: Pal Shruti Suresh , Nayak Chitra Shivanand , Kura Mahendra M , Banodkar Pravin , Tiwary Pamit , Pathak Rahul 
Published: November 2024

Mupirocin (MUP), a potent antibacterial agent, has been a cornerstone of topical antimicrobial therapy for several decades. As an older, yet widely used antibiotic, MUP has exhibited efficacy against various bacterial strains, making it a versatile tool in the management of a range of infections. The review synthesizes available literature to highlight the evolution of MUP, from its initial discovery to its current status as a go-to topical antibiotic. In the era of rising antibiotic resistance, MUP is positioned as a valuable therapeutic option due to its broad-spectrum activity against gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Emphasis is placed on its distinctive role in different infections, enhanced efficacy with different additives, and newer drug delivery strategies.In addition to its classical applications in impetigo and other superficial skin infections, this review delves into emerging indications and novel uses of MUP, potentially expanding its clinical utility. The exploration of combination therapies, alternative formulations, and ongoing research endeavors will contribute to a forward-looking perspective on the role of MUP in future antimicrobial strategies.
A comparative study of efficacy of platelet rich fibrin and conventional saline dressing in chronic non-healing ulcers: A randomized controlled trial in a tertiary care centre, Chengalpattu, Tamil Nadu
Authors: Kathirvel Dhanalakshmi , P Vanmathi , K Ganesa Sooria , A Sudarvizhi 
Published: November 2024

Non-healing ulcers pose a significant risk for deformities and platelet-rich fibrin (PRF) emerges as a promising treatment modality with feasible, easy, cost-effective day care therapy for chronic non-healing ulcers, exhibiting notable improvement in these chronic conditions. This study aims at demonstrating the efficacy of PRF (platelet rich fibrin) dressing in chronic non- healing ulcers.A prospective study with Forty patients of chronic non-healing ulcer aged more than 18 years are recruited, treated with PRF dressing and normal saline dressing. PRF dressing is repeated every week for 4 weeks and for normal saline dressing it is done every alternate days for the same period. Photographs were taken before treatment and at every subsequent session and sizes are measured in baseline (1) and 2,3,4 weeks. Each patient was followed up after four weeks from the last visit.In this study, excellent improvement was seen in 57% of total ulcers, 15% have showed moderate improvement. PRF dressing have shown significant improvement with &#62;75% improvement in the size of the ulcer in visit 3 where as normal saline have shown only 34% improvement in 3 visit. Depth of the ulcer improved to 100% and 35% in visit 3 for PRF and normal saline dressing respectively.This study have found that PRF dressing has shown significant reduction in the overall size of the ulcer and quality of life with minimal visits and without any adverse events.
Dermatological manifestations in diabetes mellitus and its relation with HbA1c levels – An observational study
Authors: Karra Manisha Chinmayi , Maheswari Palle Mokshagna , Atluri Swetha chowdary , Samanthula Haritha 
Published: November 2024

Diabetes Mellitus is a chronic, metabolic disease characterised by elevated levels of blood glucose, which over time leads to serious damage. The most common is type 2 diabetes which occurs when body becomes resistant to insulin or doesn’t make enough insulin. Skin manifestations are seen generally in pre-diabetes, undiagnosed, long-term and uncontrolled diabetes mellitus. Skin symptoms may help in diagnosing a denovo case and may give an insight into the patient's diabetic status. This is a cross-sectional, observational study conducted in patients attending the outpatient departments of Dermatology, General Medicine and those admitted under these departments over a period of four months. Clearance from Institutional Ethics Committee was taken before the start of the study. A sample population of 100 was selected randomly based on inclusion and exclusion criteria. Glycaemic profiles including HbA1c were done. Infections (35%) were the most common cutaneous symptoms, followed by papulosquamous illnesses (19%), autoimmune diseases (7%), obesity-related (6%), diabetic vasculopathy-related (5%) and miscellaneous conditions (28%), which included generalised pruritus and xerosis etc. The majority of infections were superficial fungal infections, followed by bacterial and viral infections. Dermatophytosis accounted for a majority of superficial fungal infections. Significant correlation was found between higher HbA1c levels and infections, papulo-squamous diseases, auto-immune diseases, obesity-related manifestations.Higher HbA1c levels were found to be significantly associated with a variety of cutaneous symptoms such as infections, papulosquamous illnesses, autoimmune disorders, and obesity-related manifestations.
Effect of hyperhidrosis on quality of life and its correlation with anxiety
Authors: Chaudhary Azra Ferheen , Monga Prabhnoor , Manjhi Mukesh , Sagar Vivek , Mohan Sneha 
Published: November 2024

Hyperhidrosis, characterized by excessive sweating beyond thermoregulatory needs, affects about 3% of the global population. This condition, often underreported and underdiagnosed, significantly impairs quality of life (QoL) and may correlate with increased anxiety.This study explores the impact of hyperhidrosis on QoL and examines its correlation with anxiety levels among affected individuals.A qualitative and correlational study was conducted over two months, involving 70 participants who met inclusion criteria from an initial screening of 366 individuals. Data were collected using a QoL questionnaire and the State-Trait Anxiety Inventory (STAI). Participants were recruited through snowball sampling from a dermatology department and social networks.Of the 70 participants, 91.4% reported that excessive sweating adversely affected their daily lives. Key areas impacted included physical activities (37.1%), hobbies and chores (50%), work and career (24.3%), use of technology (37.5%), physical discomfort (62.8%), and clothing choices (50%). Psychosocial effects were substantial, with 88.6% of participants experiencing negative emotions, 78.5% reporting nervousness and lack of self-confidence, and 82.8% avoiding social interactions. STAI results indicated that 11.4% had no or low anxiety, 52.8% had moderate anxiety, and 35.7% had high anxiety. The severity of hyperhidrosis correlated with higher anxiety levels. Hyperhidrosis profoundly impacts QoL and is strongly associated with elevated anxiety levels. Despite its significant effects, there is a lack of awareness and understanding of hyperhidrosis among sufferers and healthcare providers. Enhancing awareness and implementing appropriate interventions are crucial to improve the QoL and mental health of individuals with hyperhidrosis.
Evaluation of the minor clinical features of Hanifin and Rajka amongst children with atopic dermatitis, visiting a tertiary care hospital in North Eastern India
Authors: Chatterjee Shreeni , Gupta Bhaskar , Das Debajit 
Published: November 2024

Atopic Dermatitis (AD) is a commonly encountered, extremely itchy, chronic and relapsing skin disorder, which is characterized by inflammation in the skin. It typically has its onset in childhood, presenting with eczematous lesions; and can also be associated with personal or family history of “atopy”, usually most often. The criterion put by Hanifin and Rajka, encompassing 4 major plus 23 minor criteria, is not infrequently used as a diagnostic criterion for this disease in a hospital setup; however, the frequency of occurrence of the minor criteria usually varies in the population.The study aims at estimating the frequency of the minor diagnostic criteria of the Hanifin and Rajka in children with AD. This was a hospital-based cross-sectional study, that was conducted on 70 children (less than 18yrs of age) by taking their history, doing clinical and ophthalmological examination and some basic tests.The most common occurrence amongst the minor criteria estimated from our study was xerosis i.e., in 45(64.2%). The other common minor criteria observed were pityriasis alba (42.8%) facial erythema (40%), orbital darkening (37.14%) Early age of onset was seen in children (35.7%). There is variation in the clinical features of AD according to geography and population. The prevalence and severity of the disease are dependent on several factors like ethnicity/race and environment. Hence, it is important for dermatologists to know the usual and common ways the disease presents, in a given population for the diagnosis so as to diagnose and treat the patients at an earlier stage and before significant discomfort.
Unveiling the invisible: Utility of direct immunofluorescence in non-bullous skin lesions
Authors: K Madan , Rai Preethi , C S Jayaprakash , Bhat Ramesh M , T Umashankar , Sherikar Priti 
Published: November 2024

Histopathology is the cornerstone for diagnosis of dermatological conditions, with developments in immunopathology; direct immunofluorescence is a proven adjunct in bullous and non-bullous disorders. Here we emphasize the role of direct immunofluorescence in non-bullous diseases encountered in clinical practice. This is a descriptive, ambispective study conducted over a period of 3 years, where all clinically observed non-bullous disorders were included. The samples were processed for histopathology and direct immunofluorescence and results observed. The collected data was evaluated and analyzed and the clinical, histopathological and DIF diagnosis were compared across each other.Our cohort consisted of 61 cases of non-bullous lesions, of total 141 skin samples received for direct immunofluorescence. Majority of cases were vasculitis(44%), followed by lichen planus(24%), lupus erythematosus(6%), and psoriasis(5%) among others. An overall good clinic-histological concordance(87%) was noted with positive direct immunofluorescence findings in 68.85% cases. Direct immunofluorescence was crucial in establishing the diagnosis of vasculitis and further categorization into Henoch-Schonlein purpura(IgA vasculitis), diagnosis of case of lichen planus & lupus erythematosus with non-specific histomorphology and in ruling out of dermatitis herpetiformis.Direct immunofluorescence could be crucial in diagnosis of certain non-bullous disorders where; no diagnosis was possible due to nonspecific characteristics. In such cases, direct immunofluorescence is a rapid, efficient and convenient tool in diagnostic dermatology. However, the clinical, histopathological and direct immunofluorescence findings are always to be considered together for a definitive final diagnosis.
Patchy acute effluvium in and around the donor area following FUE hair transplant and its predilection for two-day session and high graft extraction cases
Authors: Mir Mubashar Mashqoor , Sharma Sumit , Sharma Mona 
Published: November 2024

: With the advancements in Follicular unit extraction (FUE) technique of hair transplant (HT) advanced grades of baldness are taken up nowadays requiring higher donor grafts and surgery often extends to the second day. This has brought into light some lesser known complications of hair transplant like acute donor site effluvium (ADE).Data on ADE is scanty; more research is needed on associated clinico-etiological factors and presentations of the condition.of our study was to study various clinico-epidemiological factors in patients of acute donor effluvium and to assess the relationship of number of grafts extracted with severity of ADE. : It was a centre based retrospective cross sectional study in which 30 patients of ADE were enrolled. Clinical and photographic record of all patients of ADE presenting in the last 3 years was screened. Age, gender, co-morbidities, personal habits, grade of androgenetic alopecia, total graft extraction, severity of hair loss and duration of surgery was compiled along with photographs and follow up notes. Mean age of patients was 33.9±5.4 years. All patients were male. Out of 30 patients 5(16.6%) were smokers and 7(23.3%) alcoholic. In 22(73.3%) of the cases of ADE the HT lasted for more than a day. The maximum duration of surgery in all cases didn’t exceed 2 days. Out of 30 cases of ADE, total grafts extracted exceeded 4000 in 28(93.3%) of cases; only 2(6.7%) of the cases had a graft extraction of &#60;4000. There was a significant and direct correlation between the severity of ADE hair loss (using SALT score) and the number of total scalp grafts extracted (r=0.657, p=0.024). ADE was seen more with advanced baldness requiring high scalp graft extraction of &#62;4000 grafts and when surgery extended to second day. Hair loss in ADE correlated directly with the number of scalp grafts harvested.
Aberrant presentations of erythema nodosum leprosum
Authors: Lakshmi Anbu , P Saraswathy , R Sowmiya , V Anandan , Purushothaman Prakatha 
Published: November 2024

Erythema nodosum leprosum (ENL) typically manifests as tender, coppery nodules accompanied by systemic symptoms and visceral involvement. However, rare morphological variants, such as erythema nodosum necroticans, EMF-like ENL, Sweet Syndrome-like ENL, the Lucio phenomenon, and vesiculobullous have also been documented. This study aims to outline the aberrant presentations of ENL and correlating it with possible triggers like COVID infection.Records of Erythema nodosum leprosum patients for the period of 3 years were collected and patients with aberrant presentations were analysed retrospectively in terms of age, sex, onset of ENL episode, number of ENL episodes, spectrum of leprosy, morphology of lesions,systemic complications, bacteriological index, COVID status and treatment given.Nineteen patients were included in the study. ENL necroticans is the commonest presentation followed by ecthyma like ENL and sweet syndrome like ENL. Almost all patients 14/19(73%) has given the history of COVID infection prior to the onset of ENL and has underwent treatment. The mean ENLIST score of COVID infected individuals was 8 compared to mean ENLIST Score of covid non infected individuals which was 5.Aberrant presentations of ENL can frequently be misdiagnosed, especially in patients without a prior diagnosis of leprosy. Thus, it is crucial to maintain a strong suspicion in these cases to avoid delays in diagnosis and the resulting complications.
Deciphering the enigma of glomus tumors: A case series
Authors: Bhosale Anand Ashok , Pol Jaydeep Nilkanthrao , Sawant Rashmi Gaurav , Dugad Vivek Jawahar , Sabnis Ajay Laxman , Pol Vaishali Jaydeep , Chaudhari Pallavi Sachin , Bakare Sudhir Manohar , Awake Praneet Pradeep , Bindu Rajan Shamrao 
Published: November 2024

Glomus tumors are rare contributing to less than two percent of all soft tissue tumors. Given the rarity of this tumor, there is a possibility of low suspicion and a missed clinical diagnosis. This case series suggests diagnostic and morphological clues for early diagnosis of this tumor.This retrospective study includes nine interesting cases of glomus tumors from January 2015 to January 2024. Data was tabulated and analysed by descriptive statistics using Microsoft Excel 2016. In this series the glomus tumors showed a mean age of (37.67± 17.5 years). Male to female ratio was 1.25:1. Most common sites were digital parts of extremities (5/9, 55.56%). Four of these digital locations were subungual (4/5, 80%). The left side (5/9, 55.56%) was the most common laterality. Duration of symptoms till diagnosis was established showed a median of three months [range was one month to nine years]. All nine cases presented with pain. The mean size of glomus lesions was 2.1±1.5 cm). Multiplicity was observed in (2/9, 22.22%) cases. Eight cases were benign (8/9, 88.89%) while one was malignant (1/9, 11.11%). Two out of these eight benign cases were glomangiomatosis. Excision biopsy was the surgical procedure performed in all of our benign cases while the malignant case was treated with amputation of the finger.Diagnosis of glomus tumors requires a high index of clinical suspicion, especially in extra-digital locations. Awareness is essential for early diagnosis and treatment of this lesion, as it is an extremely painful condition and pain is out of proportion to the size of the lesion. Magnetic Resonance Imaging (MRI) is the first investigation of choice for imaging. An early biopsy can confirm the diagnosis of a glomus tumor in time. Complete surgical excision is curative with a low risk of recurrence.
Clinico-histopathological characteristics and management outcome of rare chronic infective granulomatous diseases: A case series study
Authors: Sravani Gedela , Unnikrishnan Pooja , Vijayashree Jami , Sriya Chalamalasetty Sai 
Published: November 2024

Granulomatous skin diseases are common cutaneous dermatoses commonly encountered by practicing dermatologist. Granulomatous skin lesions are distinctive pattern of chronic inflammatory response of skin due to reaction against various organic and inorganic antigens. Granulomas are characterized by focal collection of epithelioid cells or histiocytes, admixed with variable number of leucocytes (especially mononuclear cells) and multinucleated giant cells. Granulomatous reaction is a type IV hypersensitivity reaction evoked by poorly soluble reactive substances. Incidence and prevalence of different types of granulomatous dermatitis depend on geographic location. Granulomatous skin lesions are common in the eastern parts of India. Many granulomatous skin lesions have identical histomorphology and conversely a single pathology can produce varied histological features. Some rare suppurative chronic granulomatous skin diseases include Botryomycosis, Actinomycosis, Rhinosporoidosis, Nocardiosis, and Cutaneous Tuberculosis. To describe clinical, histopathological features and treatment outcome of rare chronic infective granulomatous diseases. In this observational case series study, we retrospectively analysed six biopsy proven cases of rare chronic infective granulomatous diseases presented to our department (OPD) of Dermatology, Venereology and Leprosy (DVL) over a period of six months between June 2023 to November 2023 at Great Eastern Medical School and Hospital (GEMS), Srikakulam, Andhra Pradesh, India. The patient’s full clinical history, morphology of lesions, histopathological findings and treatment outcome were analysed. Along with histopathology, other necessary laboratory investigations were performed if required. A total of six patients were involved in the study, of whom four were males and two were females. The male to female ratio was 2:1, with a slight male majority. The most common age group was 31-40 years for both males and females. Painful raised lesion for long duration was the predominant complaint among those patients. Out of these six rare chronic granulomatous diseases, bacterial infections were common than fungal infection. All the cases showed clinical improvement after one month of starting treatment.: Most of the patients had a chronic history with improper treatment. So, it is imperative that the clinical diagnosis has to be confirmed with histopathology for the definitive diagnosis and appropriate treatment of these rare chronic infective granulomatous diseases. All these rare cases showed excellent progress after starting the right treatment.
Critical approach for drafting scientific paper procedures & practice
Authors: Paliya Nikita , Chaudhry Sunil , Pandit Rakesh 
Published: November 2024

In today's informative age, producing a well-structured scientific paper is critical for ensuring that research is read, well understood, and valued. This work focuses on the key components of a modern scientific article, providing practical advice on structure, writing, and formatting in the classical IMRAD style (Introduction, Methods, Results, and Discussion). By following this methodology and resolving frequent issues, researchers can create clear and impactful papers that stand out in a academic orbit. Target writing for a scientific paper: When you begin writing about your research, begin with a specific target journal in mind. The ability to accurately describe ideas, protocols/procedures, and outcomes are the pillars of scientific writing.