bluuebunny/crossref_metadata_2025_split huggingface dataset:
Affinity and Influence of Federico García Lorca on the Poetry of Dai Wangshu
Authors: Jiajing Song 
Published: January 2019

As one of the most representative modern poets in China, Dai Wangshu not only contributs a lot to the development of the modern Chinese poetry, but also plays an important role in introducing western poetics to China. Dai’s translation of western poetry has a profound influence on his poetic creation. Dai, throughout his poetic career, was at first influenced by the French romanticism, then was fascinated by the French symbolism and post-symbolism. The years of Disaster, a collection of poems in his later years, however, demonstrates an inclination to the Spanish modernist poetry, especially to the poems of Federico García Lorca, one of the most representative poets of the Generation of 27. This paper focuses on analyzing the characteristics of the works of these two poets, Dai Wangshu and Lorca, and is intended to make a comparative study of the affinities and similarities in their poetic beliefs and practice and the Lorca’s deep influences on Dai’s poetic creation, thus filling the blank in this field.
Rememorando o perigo: os discursos da mídia nas sucessivas retomadas dos grandes acidentes de origem científico-tecnológica
Authors: Rocha Ferreira Maria Conceição , Dill Orrico Evelyn Goyannes 
Published: January 2019

Embora focando o discurso jornalístico, este artigo discute a relação entre a informação apresentada em veículo de comunicação e sua repercussão no imaginário social. Essa aproximação entre as questões informacionais e as comunicacionais permite refletir teoricamente a respeito de seus impactos sobre a construção simbólica da população que recebe a informação. Além disso, ilustra o aparato teórico que estabelece relação direta entre informação e memória. É o que será abordado neste artigo. A referência a alguns dos piores desastres no cenário mundial leva em consideração aqueles que tiveram maior efeito sobre as pessoas e o meio ambiente. Observar os discursos jornalísticos empregados nos aniversários de grandes tragédias pode ajudar a descobrir o que pode ser apreendido em relação à essas rememorações periódicas que a mídia realiza, no intuito de compreender seu impacto no imaginário social. A rememoração cíclica dos grandes acidentes mundiais é o viés escolhido para analisar a memória de construção do discurso provocador do medo atômico. Trabalha-se com as múltiplas representações que a ideia de tempo pode ter dentro do jornalismo e observa-se que, ao celebrizar este ou aquele acontecimento, repetindo-o a cada período de tempo, a mídia se aproveita dele para autopromoção. O tempo e a memória representam estratégias discursivas para o jornalista, pois os vários usos do passado podem construir novas redes de sentido aos acontecimentos atuais, fazendo com que o valor-notícia desses fatos aumente. Como ilustração dessa premissa, analisam-se alguns artigos de celebrações de acidentes de origem nuclear: Chernobyl, em 1986, e Fukushima, em 2011, através dos quais, devido à uma distância temporal de 25 anos, é possível observar e ponderar sobre os discursos pré-construídos e os discursos transversos a esses acontecimentos, em um processo histórico de interpretação e de disputa na produção de sentidos.
Effect and mechanism of YH0618 granule on chemotherapy- induced hair loss in patients with breast cancer: study protocol for a randomized, double-blind, multi-center clinical trial
Authors: You Jie-shu , Guo Li , Huang Mei , Shi Xin-lei , Lin Man-di , Guo Zhen , Cao Ya-li , Sun You-zhi , Liu Ming-ming , Liu Huan-lan , Xu Qian , Lin Yi , Chen Qian-Jun , Chen Jianping 
Published: January 2019

Abstract
Background: Hair loss is the one of the most common side effects of chemotherapy, which can cause persistent negative emotions, further affecting therapeutic effects and reducing the quality of life. However, there is no clinically safe and effective methods to solve the problem at present. Our previous clinical and animal studies have shown that YH0618 medicinal and edible decoction could significantly promote hair growth in cancer patients after chemotherapy, and will not interfere with the anti-tumor effect of chemotherapy. Besides, the theory of Chinese Medicine believe “Essence of the kidney is reflected on the hair”. Therefore, this study will further explore the efficacy of YH0618 granule on chemotherapy-induced hair loss in patients with breast cancer by a randomized, double-blind, multi-center clinical trial and elucidate the potential mechanism from the aspect of kidney deficiency or renal dysfunction.
Methods/Design: Eligible breast cancer patients who will start chemotherapy will be randomly divided into group A (YH0618 granule) and group B (placebo). The chemotherapeutic agents contains Taxanes or/and Anthracyclines, and chemotherapy regimen will last at least 6 cycles with every three weeks a cycle. Subjects assigned to group A will receive YH0618 granules two times a day (6 g each time), 6 days a week, mixing with 200 ml warm water from the first to the fourth chemotherapy cycle. Subjects in group B will receive the placebo granule in the same manner. The primary outcome end point is successful hair preservation assessed using WHO Toxicity Grading Scale (grade ≤II), and objective indexes of hair loss levels, hair density and quality recorded by a hair and scalp detector before the fifth chemotherapy. Secondary outcomes include assessment of quality life, routine blood test, hepatic and renal function, and some medical indicators which can reflect kidney deficiency in Chinese Medicine.
Discussion: This research is of great significance for the treatment of cancer and improving the quality of life of patients. The study may provide the most direct evidence for meeting clinical needs and lay a solid scientific foundation for later product development.
Trial Registration: The trial was registered on 14 December 2018 at Chinese Clinical Trial Registry: ChiCTR1800020107.
Keywords: Medicinal and edible compound prescription, YH0618 granule, chemotherapy-induced hair loss, Taxanes, Anthracyclines, Kidney deficiency and renal dysfunction, Quality of life.
Effects of the Chinese herbal formula San-Huang Gu-Ben Zhi-Ke treatment on Stable Chronic Obstructive Pulmonary disease:study protocol of a randomized, double-blind, placebo-controlled trial
Authors: Zu Yaqi , Li Demin , Lei Xiang , Zhang Hongchun 
Published: January 2019

Abstract
Background: Due to the large number of patients, high mortality rate as well as high social costs and economic burden, Chronic obstructive pulmonary disease（COPD）has become one of the most important health problem around the world, which has attracted people's attention. Currently, Chinese herbs have been widely used as alternative medicine（CAM）for COPD patients. Chinese herbal formula San-Huang Gu-Ben Zhi-Ke（SHGBZK）have shown good clinical efficacy in COPD in preclinical studies. Animal experiments have enhanced that it has mucosal immune barrier function, it can maintain airway wall integrity, reduce inflammatory cell infiltration, promote inflammatory damage repair, and relieve airway narrow conditions.
Methods/design: The study is a randomized, double-blind, placebo-controlled trial. A total of 100 COPD patients at stable stage that diagnosed with syndrome of deficiency of lung qi and spleen qi will be recruited and randomly assigned to one of the two treatments group, with 50 in each group. One hundred COPD patients were randomly assigned to two treatment groups（SHGBZK treatment, N=50; placebo treatment, N=50).The two groups will receive basic treatment for COPD according to the 2017 GOLD Guidelines for Chronic Obstructive Pulmonary Disease. Patients will stick to the treatment they used to take as much as possible, and will be given present general treatment when AECOPD occurs during the study. Both groups will receive an 24-weeks intervention, and patient status was assessed at 24 weeks later and 28 weeks after treatment. After the 24-weeks treatment, another 28 weeks will be followed up. The outcome measures including the frequency and duration of acute exacerbation, lung function, TCM symptom score, exercise capacity, and quality of life will be assessed.
Discussion: It is hypothesized that SHGBZK will have beneficial effects in reducing the frequency and duration of acute exacerbation, improving exercise capacity function of COPD patients at stable stage that diagnosed with syndrome of deficiency of lung qi and spleen qi. This study may establish a new method for COPD patients, and thus differentiation from other drugs used for similar clinical indications in clinical use.
Trial registration: Chinese Clinical Trial Registry, ID: ChiCTR1800016349. Registered on 26 May 2018.
Keywords: Chronic obstructive pulmonary disease; traditional Chinese medicine; Chinese herbal formula San-Huang Gu-Ben Zhi-Ke; clinical trials; clinical protocols.
Complete reconstruction of anterior segment surgery for a patient with traumatic cataract and iris defects: a case report
Authors: Wang Zhenyu , Li Xuemin 
Published: January 2019

Abstract
Background: Ocular trauma has relationship with variable damage towards anterior segment or posterior segment. Among them, cornea, iris and lens are vulnerable to injury. For patients with traumatic cataract and other anterior segment trauma， complete reconstruction of anterior segment surgery can be a good option to restore patients’ anterior segment that helps them regain their vision.
Case presentation: We presented a case of traumatic cataract with iris defects after explosive trauma. A surgery was done to fully reconstruct the anterior segment of the patient’s left eye including separating posterior synechia of iris, removing cataract and implantation of IOL. Postoperatively, the patient didn’t complain about photophobia anymore and the uncorrected visual acuity (UCVA) of the patient reached from counting fingers to 20/25 and remained stable on follow-up at 1 week and 1 month.
Conclusion: Our case suggested the importance of completely reconstruct anterior segment for patients who have traumatic cataract with traumatic iris defects and its benefits for society.
Keywords: Traumatic cataract; Traumatic iris defect; Surgery
Designing A Language Lesson: Pedagogical and Linguistic Perspectives
Authors: Hidayat Didin Nuruddin 
Published: January 2019

Designing a language lesson is a challenging task for teachers. In order to have a good language lesson, teachers cannot just rely on the textbook. They need at least to develop the lesson from the textbook or even to design their own lesson. Teachers also need to consider how they are going to apply the lesson planned in the classroom. Another consideration would be to integrate the specific language skill and/or element with the other skills. This is essential in order to achieve the utmost results of teaching and learning. This paper discusses a language lesson in the area of grammar - Used To - designed by the author. The lesson is not only intended to expose learners with the structure and rules of grammar, but also allow learners to practice the grammar in use. Hence, the developed grammar lesson aimed to improve the communicative competence of the learners. Considering the wide aspect of teaching analysis, the present article focuses on the application of the lessons in the classroom, the aspects of language skills covered, as well as the linguistic foundation for the exercises. It is hoped that this article can provide insights to language educators in developing grammar lessons that cater to the considerations of pedagogical and linguistic perspectives.
Knowledge management practicesin oil companies
Authors: Bezginova Yu. A. , Garanina T. A. , Kudryavtsev D. V. , Pleshkova A. Yu. 
Published: January 2019

The purpose of the study.In the economy of the 21st century, knowledge is the main source of obtaining sustainable competitive advantages of enterprises, and knowledge management (KM) is the main mechanism for ensuring and maintaining it. People and knowledge they possess, know-how, ability to innovate, trust relationships with customers and partners, and other intangible assets are becoming the most important sources of development for an organization. KM is traditionally carried out with the help of the following components: information technology, organizational processes and structures, corporate culture and people. In addition, there are complex tools of KM, which usually combine several KM components: a library of documents (knowledge base, corporate memory), communities of practice, lessons learned, etc. The purpose of this study is to illustrate the application of KM practices in companies in the oil industry of the Russian Federation.Materials and methods.This article used the analysis of secondary data sources, and also reviewed in detail two cases, describing KM in the activities of oil companies in Russia. In order to understand at what stage is the development of the knowledge management system (KMS) in oil companies of Russia it’s necessary to compare the use of KM tools in foreign and domestic practice, this paper is based on information, provided in open sources. Observations are formed and the most prominent examples of the use of KM tools are indicated.Results.The article provides an overview of KM tools, examples of their use in the oil and gas industries, and also examined the domestic practice of their use, based on cases of Russian oil companies. Examples of the use of KM tools, based on technologies and employees in foreign and Russian oil companies are pre-sented. On the example of cases of two well-known Russian oil companies, the stages of formation and de-velopment of knowledge management system in a company were considered, specific practices of KM, which appeared in companies at the respective stages of KMS development, were presented, as well as fea-tures of KM in each company.Conclusion.For a number of reasons, oil companies are advocates of the proactive use of KM systems. In the course of the analysis, the trends of KM in the oil sector of the Russian economy were identified: com-plexity of use, poor acceptance of innovations, not related to production/technological processes, the begin-ning of the emergence of a policy of active knowledge sharing, a move towards creating a flexible KM sys-tem. This article will draw the attention of Russian managers to the issue of knowledge management and other intangible assets and identify management practices that will help Russian companies to successfully develop and compete, based on their intellectual capital. The article will also be of interest for specialists in knowledge management and practitioners from related fields.
The use of business games in the education of masters in the program “Protection of information space of economic activity”
Authors: Sizov V. A. 
Published: January 2019

The aim of the study is to develop the concept of the use of business games in the master’s program in the direction of “Information security” from the perspective of practical training methods and means of protection of information space of enterprises and organizations, as well as other economic subjects.Materials and methods. The basis for the development of the concept of the use of business games in the education of masters in the direction of “Information security” are the Federal state educational standard and professional standard “Specialist in the protection of information in automated systems.” The concept of the business game defines the requirements for the specification of the rules of interaction of participants (actors) of the information and educational space in accordance with their role features, taking into account the implementation at the organizational level of the EIF (European Interoperability Framework).Results. The article presents the concept of using business games in preparing masters for the program “Protecting the Information Space of Economic Actors”, substantiates the need to use business games for specific disciplines of the program, proposes an approach to implementing business games in the educational process based on the interaction of key actors in the information and educational space built on the basis of virtualization technologies.Conclusion. The use of business games in the educational process of masters in the program “Protection of the information space of economic activity” contributes to the formation of the necessary professional competencies, taking into account the features of the components of the information space of economic activity: information resources, means of information interaction and information infrastructure.
The overview of open education development tendencies in Russia and Canada
Authors: Sosnina N. G. 
Published: January 2019

The aim of research is to describe the foreign experience of open educational resources implementation in higher education on the example of Canada. The concept of open education in this country requires federal and regional support from the government. Currently, there is a number of initiatives, aimed at maximizing the development of open educational resources. An increasing number of open educational resource initiatives in Canadian universities offer free courses to both Canadians and international students. National open education initiatives include the following projects: “Open Data”, the federal government “pilot” project; support of Canadian Council of Ministers of Education within 2012 Paris Open Educational Resources Declaration; and the Creative Society of Canada. British Columbia and Alberta support open educational resources as a part of the most important open education initiatives at the regional level. However, a number of problems prevent the full development of the open education system.Materials and methods of research include discourse-analysis of domestic and foreign scientific sources, devoted to the problems of open education. The methodological basis is the study of the legal framework of open education, a retrospective analysis of the open education development process in Canadian universities and the analysis of existing open educational projects.The results of the study show that the need to implement the policy of open education imposes new requirements to the process of determining the level of educational programs development and the formation of a unified system of formal credits.Conclusion. The Canadian examination of open educational resources regulates all sectors of education and training in the country. This examination is a review of the results of open education principles implementation at the national and regional levels. The article discusses the features of both regional and foreign projects functioning. The advantages of open educational policy for different segments of the population are described.
Bacopa monnieri Supplements Offset Paraquat-Induced Behavioral Phenotype and Brain Oxidative Pathways in Mice
Authors: Krishna Gokul , Hosamani Ravikumar , Muralidhara  
Published: January 2019

Background:Parkinson’s Disease (PD) is characterized by alterations in cerebellum and basal ganglia functioning with corresponding motor deficits and neuropsychiatric symptoms. Involvement of oxidative dysfunction has been implicated for the progression of PD, and environmental neurotoxin exposure could influence such behavior and psychiatric pathology. Assessing dietary supplementation strategies with naturally occurring phytochemicals to reduce behavioral anomalies associated with neurotoxin exposure would have major clinical importance. The present investigation assessed the influence of Bacopa monneri (BM) on behaviors considered to reflect anxiety-like state and motor function as well as selected biochemical changes in brain regions of mice chronically exposed to ecologically relevant herbicide, paraquat (PQ).Materials & Methods:Male mice (4-week old, Swiss) were daily provided with oral supplements of standardized BM extract (200 mg/kg body weight/day; 3 weeks) and PQ (10 mg/kg, i.p. three times a week; 3 weeks).Results:We found that BM supplementation significantly reversed the PQ-induced reduction of exploratory behavior, gait abnormalities (stride length and mismatch of paw placement) and motor impairment (rotarod performance). In a separate study, BM administration prevented the reduction in dopamine levels and reversed cholinergic activity in brain regions important for motor (striatum) pathology. Further, in mitochondria, PQ-induced decrease in succinate dehydrogenase (SDH) activity and energy charge (MTT reduction), was restored with BM supplementation.Conclusion:These findings suggest that BM supplementation mitigates paraquat-induced behavioral deficits and brain oxidative stress in mice. However, further investigations would enable us to identify specific molecular mechanism by which BM influences behavioural pathology.
Patient-Specific Static Structural Analysis of Femur Bone of different lengths
Authors: Chethan K.N. , Bhat Shyamasunder N. , Zuber Mohammad , Shenoy Satish B. 
Published: January 2019

Background:The femur bone is an essential part of human activity, providing stability and support in carrying out our day to day activities. The inter-human anatomical variation and load bearing ability of humans of different heights will provide the necessary understanding of their functional ability.Objective:In this study, femur bone of two humans of different lengths (tall femur and short femur) were subjected to static structural loading conditions to evaluate their load-bearing abilities using Finite Element Analysis.Methods:The 3D models of femur bones were developed using MIMICS from the CT scans which were then subjected to static structural analysis by varying the load from 1000N to 8000N. The von Mises stress and deformation were captured to compare the performance of each of the femur bones.Results:The tall femur resulted in reduced Von-Mises stress and total deformation when compared to the short femur. However, the maximum principle stresses showed an increase with an increase in the bone length. In both the femurs, the maximum stresses were observed in the medullary region.Conclusion:When the applied load exceeds 10 times the body weight of the person, the tall femur model exceeded 134 MPa stress value. The short femur model failed at 9 times the body weight, indicating that the tall femur had higher load-bearing abilities.
Serum Neutrophil Gelatinase-associated Lipocalin Measured at Admission to Predict Mortality in Sepsis-associated Acute Kidney Injury of Vietnamese Critically Ill Patients
Authors: Thang Le V. , Tuan Pham N. H. , Kien Nguyen T. , Dung Nguyen T. T. , Tue Nguyen T. , Duong Nguyen D. , Ha Nguyen T. T. , Van Diem T. , V. Duc Nguyen , Nghia Vu X. , Dung Nguyen H. , Huong Nguyen T. T. , Dung Pham T. 
Published: January 2019

Purpose:
To evaluate incidence of sepsis-associated acute kidney injury (SA-AKI) in the AKI Intensive Care Unit (ICU) patients and predictive value of Neutrophil Gelatinase-Associated Lipocalin (NGAL) measured at the admission in mortality of SA-AKI and non SA-AKI.

Patients and Methods:
A study of 101 consecutive adult patients admitted to the Intensive Care Unit (ICU) diagnosed as AKI in which there were 60 patients with SA-AKI. Acute kidney injury was defined based on Acute Kidney Injury Network (AKIN) criteria. Serum NGAL was measured using the BioVendor Human Lipocalin-2/NGAL ELISA with blood sample taken at admission.

Results:
Incidence of septic acute kidney injury was 59.4%, incidence of death patients reached 20.0%. Mean concentration of serum NGAL in death group was 633.56 ng/ml, higher significantly than that of survival patients (328.84 ng/ml), p<0.005. Serum NGAL in non SA-AKI patients showed a better prognostic value to predict hospital mortality than that in SA-AKI patients (AUC: 0.894 and 0,807 respectively; p < 0.005)

Conclusion:
In SA-AKI patients, serum NGAL and mortality rate increased along with the stage of AKI. Serum NGAL, measuring at admission time, was a good prognostic biomarker of mortality in both SA-AKI and non SA-AKI patients.