bluuebunny/crossref_metadata_2025_split huggingface dataset:
Culture Effect on Repurchasing Intention of Counterfeits Products
Authors: Alhidari Abdullah M. 
Published: March 2019

The aim of this paper is to illustrate the key cultural factors of consumers repurchase intentions toward counterfeit products. The study is also examining the influence of culture and social factors on attitudes towards counterfeiting products and repurchase intention among Saudi consumers. a survey was used, a total of 509 respondents (39% female) completed and usable responses from the sampling frame who lives in Saudi Arabia. The results indicate that consumer’s culture by itself might not explain their counterfeit products repurchase intention. The consumer’s attitude towards these products might help managers to understand their behavior. A social influence which considers as an external factor was not an important factor explaining consumers’ behavior regarding counterfeits products. The current study adds to the literature by investigating the key culture antecedents of Saudi consumers repurchase intentions toward counterfeit products. Additionally, empirical evidence contributes to the practitioners in the Saudi culture.
Changes in Intraocular Pressure and Anterior Chamber Depth after Phacoemulsification in Non-Glaucomatous Patients
Authors: Abdallah Mona , Ali Omar M. , A. Mohammad Abd El-Nasser , Soliman Wael 
Published: March 2019

Aims: To evaluate changes in intraocular pressure (IOP) and anterior chamber depth (ACD) after uneventful phacoemulsification with intraocular lens (IOL) implantation.
Study Design: Prospective interventional comparative study.
Place and Duration of Study: Department of Ophthalmology, Assuit University Hospital, Assuit, Egypt between September 2016 and October 2017.
Methodology: 100 Patients with visually significant cataract (39 males (39%) and 61 females (61%). All patients underwent uneventful phacoemulsification. Intraocular pressure and ACD were measured preoperatively by using Goldmann applanation tonometer and Ultrasonography respectively, and at 1 week, 1 month, and 3 months postoperatively.
Results: The postoperative ACD was higher than the preoperative value by 0.26± 0.06 mm at 1 week, 0.45±0.06 mm at 1 month, and 0.59±0.08 mm at 3 months postoperatively (P=.000). P < 0.05 was considered to indicate a statistically significant difference. The IOP at 1 week, 1 month, and 3 months postoperatively was lower than the preoperative value by 1.03±0.3 mmHg, 1.52±0.46 mmHg, and 2.14±0.62 mmHg, respectively (P=.001).
Conclusion: This study revealed that there was a decrease in IOP and increase in ACD after cataract extraction by phacoemulsification. Patients with ocular hypertension, open-angle glaucoma, and narrow-angle glaucoma may benefit from cataract extraction.
Room‐Temperature Mesoscopic Fluctuations and Coulomb Drag in Multilayer WSe2
Authors: Doan Manh‐Ha , Jin Youngjo , Chau Tuan Khanh , Joo Min‐Kyu , Lee Young Hee 
Published: March 2019

AbstractMesoscopic fluctuations, manifesting the quantum interference (QI) of electrons, have been theoretically proposed in bilayer Coulomb drag systems. Unfortunately, these phenomena are usually observed at cryogenic temperatures, which severely limits their novel physics for pragmatic applications. In this paper, observation of room‐temperature QI and Coulomb drag in a multilayer WSe2 transistor is reported via graphene contacts separately at its top and bottom layers. The central layers of WSe2 act as an insulating region with a width of few nanometers, which spatially separates the top and bottom conducting channels and provides a strong Coulomb interaction between them, leading to large conductance oscillations at room temperature. The gradual suppression of the oscillations with the increase in the applied magnetic field and/or injected current further confirms the QI phenomenon. With the decrease in temperature, the Coulomb drag effect is exhibited in the system owing to the increased thickness of the insulating region. This study reveals a novel approach for realization of advanced quantum electronics operating at high temperatures.
An Organic Emitter Displaying Dual Emissions and Efficient Delayed Fluorescence White OLEDs
Authors: Li Chenglong , Liang Jixiong , Liang Baoyan , Li Zhiqiang , Cheng Zong , Yang Guochun , Wang Yue 
Published: March 2019

AbstractThe design and synthesis of one‐compound‐based white light organic solids that can be employed to fabricate efficient organic white light‐emitting devices (OLEDs) still remains a challenge. In this contribution, a classic organic donor–acceptor (D‐A) type molecule (PTZ‐BP) is presented, which is composed of phenothiazine (PTZ) as an electron donor and benzophenone (BP) as an electron acceptor. Intriguingly, PTZ‐BP displays dual emission and thermally activated delayed fluorescence properties. Its dual emission originates from locally excited state and intramolecular charge transfer excited state, respectively. PTZ‐BP‐doped thin film is used to fabricate efficient white light OLEDs with external quantum efficiency of 6.2%, which is among the highest values reported for the single‐emitter‐based small molecules white fluorescence OLEDs with similar Commission Internationale de L' Eclairage (CIE) coordinates so far.
Testosterone‐dependent facial and body traits predict men's sociosexual attitudes and behaviors
Authors: Polo Pablo , Muñoz‐Reyes Jose Antonio , Pita Miguel , Shackelford Todd K. , Fink Bernhard 
Published: March 2019

AbstractObjectivesStrategic Pluralism Theory contends that human mating strategies are calibrated toward short‐term (ST) or long‐term (LT) mating according to the expression of condition‐dependent traits and characteristics of the social and physical environment. Traits reflecting the effects of testosterone have been considered condition‐dependent traits that provide information about the calibration of male mating strategy. We investigated the relationship of muscle mass and facial masculinity with attitudes and behaviors reflecting ST and LT mating tactics.MethodsWe measured skeletal muscle mass (SMM) through bioelectrical impedance and facial width‐to‐height ratio (fWHR) in a sample of Chilean men (n = 206; mean age = 22.52 ± 4.65 SD), and collected information about sociosexual attitudes and past sexual behavior.ResultsOur results showed an interaction effect of SMM and fWHR on unrestricted (but not restricted) sociosexual attitudes and past sexual behavior. Individuals with a consistent expression of both traits (ie, high SMM and fWHR or low SMM and fWHR) reported higher levels of unrestricted sociosexual attitudes and a greater number of lifetime and previous‐year sexual partners.ConclusionsThese findings suggest that the intensity and consistency of expression of body and facial masculinity is important in signaling male mating tactics and sociosexual attitudes.
Large‐Ring Cyclodextrins as Chiral Selectors for Enantiomeric Pharmaceuticals
Authors: Sonnendecker Christian , Thürmann Sebastian , Przybylski Cédric , Zitzmann Franziska D. , Heinke Nicole , Krauke Yannick , Monks Kate , Robitzki Andrea A. , Belder Detlev , Zimmermann Wolfgang 
Published: March 2019

AbstractLarge‐ring cyclodextrins (CD) are cyclic glucans composed of 9 or more α‐1,4‐linked glucose units. They are minor side products of bacterial glucanotransferases (CGTases, EC 2.4.1.19) and have previously been available only in very small amounts for studies of their properties in supramolecular complex formation reactions. We engineered a CGTase to synthesize mainly large‐ring CD facilitating their preparation in larger amounts. By reversed phase chromatography, we obtained single CD samples composed of 10 to 12 glucose units (CD10, CD11, and CD12) with a purity of >90 %. Their identity was confirmed by high resolution mass spectrometry and fragmentation analysis. We demonstrated the non‐toxicity of CD10–CD12 for human cell lines by a cell proliferation assay and impedimetric monitoring. We then showed that CD10 and CD11 are efficient chiral selectors for the capillary electrophoretic separation of the enantiomeric pharmaceuticals fluvastatin, mefloquine, carvedilol, and primaquine.
Molecular Heterostructures of Covalent Triazine Frameworks for Enhanced Photocatalytic Hydrogen Production
Authors: Huang Wei , He Qing , Hu Yongpan , Li Yanguang 
Published: March 2019

AbstractConjugated polymers have emerged as promising candidates for photocatalytic H2 production owing to their structural designability and functional diversity. However, the fast recombination of photoexcited electrons and holes limits their H2 production rates. We have now designed molecular heterostructures of covalent triazine frameworks to facilitate charge‐carrier separation and promote photocatalytic H2 production. Benzothiadiazole and thiophene moieties were selectively incorporated into the covalent triazine frameworks as electron‐withdrawing and electron‐donating units, respectively, by a sequential polymerization strategy. The resulting hybrids exhibited much improved charge‐carrier‐separation efficiency as evidenced by photophysical and electrochemical characterization. An H2 evolution rate of 6.6 mmol g−1 h−1 was measured for the optimal sample under visible‐light irradiation (λ>420 nm), which is far superior to that of most reported conjugated‐polymer photocatalysts.
The Role of Alkali Metal in α‐MnO2 Catalyzed Ammonia‐Selective Catalysis
Authors: Hao Zhifei , Shen Zhurui , Li Yi , Wang Haitao , Zheng Lirong , Wang Ruihua , Liu Guoquan , Zhan Sihui 
Published: March 2019

AbstractThe unexpected phenomenon and mechanism of the alkali metal involved NH3 selective catalysis are reported. Incorporation of K+ (4.22 wt %) in the tunnels of α‐MnO2 greatly improved its activity at low temperature (50–200 °C, 100 % conversion of NOx vs. 50.6 % conversion over pristine α‐MnO2 at 150 °C). Experiment and theory demonstrated the atomic role of incorporated K+ in α‐MnO2. Results showed that K+ in the tunnels could form a stable coordination with eight nearby O
atoms. The columbic interaction between the trapped K+ and O atoms can rearrange the charge population of nearby Mn and O atoms, thus making the topmost five‐coordinated unsaturated Mn cations (Mn5c, the Lewis acid sites) more positive. Therefore, the more positively charged Mn5c can better chemically adsorb and activate the NH3 molecules compared with its pristine counterpart, which is crucial for subsequent reactions.
Electrochemical Real‐Time Mass Spectrometry (EC‐RTMS): Monitoring Electrochemical Reaction Products in Real Time
Authors: Khanipour Peyman , Löffler Mario , Reichert Andreas M. , Haase Felix T. , Mayrhofer Karl J. J. , Katsounaros Ioannis 
Published: March 2019

AbstractMethods that provide real‐time information are essential to resolve transients occurring at dynamic interfaces. Now a powerful method is presented that enables the time‐ and potential‐resolved characterization of liquid and gaseous products of electrochemical reactions shortly after their formation. To demonstrate its extraordinary potential, the electrochemical real time mass spectrometry (EC‐RTMS) approach is used to determine the products of the CO2 reduction reaction (CO2RR) during potential step or sweep experiments on pristine and in situ anodized copper. The enhanced formation of several C2+ products over C1 products is tracked directly after copper anodization, with unprecedented temporal resolution. This new technique creates exciting new opportunities for resolving processes that occur at short timescales and eventually for guiding the design of new, robust catalysts for selective electrosynthesis under dynamic operation.
Synthesis of new antidiabetic agent by complexity between vanadyl (II) sulfate and vitamin B1: Structural, characterization, anti‐DNA damage, structural alterations and antioxidative damage studies
Authors: El‐Megharbel Samy M. , Hamza Reham Z. , Gobouri Adil A. , Refat Moamen S. 
Published: March 2019

Complexity between thiamine (vitamin B1) and VSO4.xH2O salt with the suggest formula, [VO (vitB1)2] has been synthesized by the chemical reaction in neutralization media pH = 7.5 at 70 °C. The assignments of the elemental analysis, conductivity measurements, FT‐IR, UV–Vis, ESR spectroscopy, thermal analyses (TGA‐DTA) and magnetic moment data visualize the stoichiometry, formula and chelation of the vanadyl (II) complex. The spectroscopic analyses revealed that vitamin B1 reacted with vanadyl (II) ions as a bidentate ligand via hydroxyl ethyl‐oxygen and sulfur of the thiazole group. New vanadyl (II) complex has the protective effect against pancreatic toxicity induced by STZ. The target of this investigation was to assess the enhancement effect of new vanadyl (II)complex in two doses on pancreatic toxicity, oxidative stress, DNA damage and hyperglycemia persuade by STZ. The rats were divided into 7 groups; control group, STZ (diabetic untreated group) (50 mg/kg), STZ plus thiamine (10 mg/Kg) (Low dose), STZ plus thiamine (50 mg/Kg) (High dose), STZ plus VSO4. xH2O (15 mg/kg), STZ + vanadyl (II) complex (10 mg/Kg) (Low dose), STZ+ vanadyl (II) complex (50 mg/Kg) (High dose). Vanadyl (II) complex in high dose afforded a significant decline in MDA level parallel to significant elevation in antioxidant enzymes (SOD, CAT, MPO and XO) in pancreas homogenates. It may be due to the capturing activities of reactive oxygen species by the new complex, which reduces oxidative damage and enhance antioxidant capacities. The novel complex succeeded in the restoration of lipid parameters to its normal levels beside lowering TNF‐α and CRP levels. The new complex also reduces hyperglycemia induced by STZ greatly and improve histological and ultrastructure of pancreas and has a high potency in reducing DNA damage in pancreatic tissues.
Development of epoxy‐cyanate ester‐clay nanocomposites offering enhanced thermally stability
Authors: Venkatesh M. , Gouthaman S. , Kanemoto S. O. , Lakshmi M. S. , Hamerton I. 
Published: March 2019

ABSTRACTThe preparation and characterization of blends of a series of dicyanate monomers such as 2,2′‐bis(4‐cyanatophenyl) propane (DCDPP), bis‐4‐cyanato‐biphenyl (DCBP), bis‐4‐cyanatonaphthalene (DCN), 3,3′‐bis(4‐cyanatophenyl)sulphide (DCTDP), 3,3′‐bis(4‐cyanatophenyl)sulphone (DCDPS), and the diglycidyl ether of bisphenol A are reported. These copolymers are combined with a montmorillionite nanoclay and both epoxy‐cyanate blends and epoxy‐cyanate blends‐nanoclay composites are all analyzed for thermal stability, thermal degradation kinetics, flame retardancy, and impact strength. The nanocomposites are further characterized by X‐ray diffraction and SEM to determine morphological features, from which structure–property relationships are determined. Dispersion of the nanoclay is of paramount importance, but its inclusion serves to improve char yield and impact strength, when this is achieved. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47754.
Impact of depth filtration on disulfide bond reduction during downstream processing of monoclonal antibodies from CHO cell cultures
Authors: O’Mara Brian , Gao Zhong‐Hua , Kuruganti Manju , Mallett Robert , Nayar Gautam , Smith Laura , Meyer Jeffrey D. , Therriault Jon , Miller Cameron , Cisney John , Fann John 
Published: March 2019

AbstractMonoclonal antibody interchain disulfide bond reduction was observed in a Chinese Hamster Ovary manufacturing process that used single‐use technologies. A similar reduction has been reported for processes that involved high mechanical shear recovery unit operations, such as continuous flow centrifugation and when the clarified harvest was stored under low dissolved oxygen (DO) conditions (Trexler‐Schmidt et al., 2010. Biotechnology and Bioengineering,
106(3), 452–461). The work described here identifies disposable depth filtration used during cell culture harvest operations as a shear‐inducing unit operation causing cell lysis. As a result, reduction of antibody interchain disulfide bonds was observed through the same mechanisms described for continuous flow centrifugation. Small‐scale depth‐filtration models were developed, and the differential pressure (Δ
P) of the primary depth filter was identified as the key factor contributing to cell lysis. Strong correlations of Δ
P and cell lysis were generated by measuring the levels of lactate dehydrogenase and thiol in the filtered harvest material. A simple risk mitigation strategy was implemented during manufacturing by providing an air overlay to the headspace of a single‐use storage bag to maintain sufficient DO in the clarified harvest. In addition, enzymatic characterization studies determined that thioredoxin reductase and glucose‐6‐phosphate dehydrogenase are critical enzymes involved in antibody reduction in a nicotinamide adenine dinucleotide phosphate (NADP
+)/NADPH‐dependent manner.
Association between polymorphisms in MicroRNA target sites of RAD51D genes and risk of hepatocellular carcinoma
Authors: Jiang Yan‐Ji , Zhong Jian‐Hong , Zhou Zi‐Han , Qiu Mo‐Qin , Zhou Xian‐Guo , Liu Ying‐Chun , Huo Rong‐Rui , Liang Xiu‐Mei , Chen Zhu , Lin Qiu‐Ling , Yu Xiang‐Yuan , Yu Hong‐Ping 
Published: March 2019

AbstractRAD51D (RAD51L3) is a member of the RAD51 gene family which plays important roles in maintaining genomic stability and preventing DNA damage. This study is aimed to investigate the associations between RAD51D polymorphisms and the hereditary susceptibility of hepatocellular carcinoma (HCC). In this study we conducted a hospital–based case‐control study including 805 cases (HCC patients) and 846 controls (nontumor patients) in Guangxi, China. A total of two Single–nucleotide polymorphisms (SNPs) rs12947947 and rs28363292 of RAD51D were selected and genotyped. Although we did not find two SNPs individually that had any significant main effect on risk of HCC, We found that the combined genotypes with 1‐2 risk genotypes were associated with significantly increased overall risk of HCC (OR = 1.462, 95% CI = 1.050‐2.036). According to the results of further stratification analysis, GT/GG genotype of rs28363292 increased HCC risk in zhuang people (OR = 3.913, 95% CI = 1.873‐8.175) and nonhepatitis B virus (HBV) infection population (OR = 1.774, 95% CI = 1.060‐2.969), the combined 1‐2 risk genotypes increased the risk of HCC in zhuang people (OR = 2.817, 95% CI = 1.532‐5.182) and non‐HBV infected population (OR = 1.567, 95% CI = 1.042‐2.358). Our results suggest that rs12947947 and rs28363292 polymorphisms may jointly contribute to the risk of HCC. Further large studies and functional studies are required to validate our findings.
Rutin as Deoxyribonuclease I Inhibitor
Authors: Kolarevic Ana , Pavlovic Aleksandra , Djordjevic Aleksandra , Lazarevic Jelena , Savic Sasa , Kocic Gordana , Anderluh Marko , Smelcerovic Andrija 
Published: March 2019

AbstractDNase I inhibitory potential of water extract of nine Hypericum species (H. umbellatum, H. barbatum, H. rumeliacum, H. rochelii, H. perforatum, H. tetrapterum, H. olympicum, H. hirsutum, H. linarioides) and the most important Hypericum secondary metabolites (hypericin, hyperforin, quercetin, and rutin) was investigated. All examined Hypericum extracts inhibited DNase I with IC50 below 800 μg/ml, whereby H. perforatum was the most potent (IC50=391.26±68.40 μg/ml). Among the investigated Hypericum secondary metabolites, rutin inhibited bovine pancreatic DNase I in a non‐competitive manner with IC50 value of 108.90±9.73 μm. DNase I inhibitory ability of rutin was further confirmed on DNase I in rat liver homogenate (IC50=137.17±16.65 μm). Due to the involvement of DNase I in apoptotic processes the results of this study indicate the importance of frequent rutin and H. perforatum consumption in daily human nutrition. Rutin is a dietary component that can contribute to male infertility prevention by showing dual mechanism of sperm DNA protection, DNase I inhibition and antioxidant activity.
Polymer‐Based Module for NAD+ Regeneration with Visible Light
Authors: Ma Beatriz C. , Caire da Silva Lucas , Jo Seong‐Min , Wurm Frederik R. , Bannwarth Markus B. , Zhang Kai A. I. , Sundmacher Kai , Landfester Katharina 
Published: March 2019

AbstractThe regeneration of enzymatic cofactors by cell‐free synthetic modules is a key step towards producing a purely synthetic cell. Herein, we demonstrate the regeneration of the enzyme cofactor NAD+ by photo‐oxidation of NADH under visible‐light irradiation by using metal‐free conjugated polymer nanoparticles. Encapsulation of the light‐active nanoparticles in the lumen of polymeric vesicles produced a fully organic module able to regenerate NAD+ in an enzyme‐free system. The polymer compartment conferred physical and chemical autonomy to the module, allowing the regeneration of NAD+ to occur efficiently, even in harsh chemical environments. Moreover, we show that regeneration of NAD+ by the photocatalyst nanoparticles can oxidize a model substrate, in conjunction with the enzyme glycerol dehydrogenase. To ensure the longevity of the enzyme, we immobilized it within a protective silica matrix; this yielded enzymatic silica nanoparticles with enhanced long‐term performance and compatibility with the NAD+‐regeneration system.
Epithelioid glioblastoma presenting as aphasia in a young adult with ovarian cancer: A case report
Authors: Finneran Megan M. , Georges Joseph , Kakareka Michael , Moncman Ryan , Enriquez Miriam , Siegal Todd , Kubicek Gregory , Turtz Alan , Yocom Steven , Goldman H. Warren , Barrese James 
Published: March 2019

Key Clinical MessageOur patient's clinical history and preoperative radiographic evaluation suggested central nervous system (CNS) metastatic disease. Ultimately, final pathology revealed epithelioid glioblastoma (eGBM), a newly classified CNS primary tumor. This reinforces the importance of direct tissue sampling and including eGBM on the differential for young patients with histories of systemic cancer presenting with new CNS lesions.
Agostic Interactions in Early Transition‐Metal Complexes: Roles of Hyperconjugation, Dispersion, and Steric Effect
Authors: Lin Xuhui , Wu Wei , Mo Yirong 
Published: March 2019

AbstractThe agostic interaction is a ubiquitous phenomenon in catalytic processes and transition‐metal complexes, and hyperconjugation has been well recognized as its origin. Yet, recent studies showed that either short‐range London dispersion or structural constraints could be the driving force, although proper evaluation of the role of hyperconjugation therein is needed. Herein, a simple variant of valence bond theory was employed to study a few exemplary Ti complexes with α‐ or β‐agostic interactions and interpret the agostic effect in terms of the steric effect, hyperconjugation, and dispersion. For the complexes [MeTiCl3(dmpe)] and [MeTiCl3(dhpe)] with α‐agostic interactions, hyperconjugation plays the dominant role with comparable magnitudes in both systems, but dispersion is solely responsible for the stronger agostic interaction in the former compared with the latter. For the complexes [EtTiCl3(dmpe)] and [EtTiCl3(dhpe)] with β‐agostic interactions, however, hyperconjugation and dispersion play comparable roles, and the weaker steric repulsion leads to a stronger agostic effect in the former than in the latter. Thus, the present study clarifies the variable and sensitive roles of steric, hyperconjugative, and dispersion interactions in the agostic interaction.