bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating the stability of architectural heritage from the perspective of InSAR: a practical study on Jianchuan Ancient Town
Authors: Li Menghua , Gao Xinning , Yang Mengshi , Tang Li , Tang Bo-Hui 
Published: November 2024

Abstract
The increase in human activities and natural degradation often leads to tilting, collapsing, and other forms of deterioration in architectural heritage, posing significant threats to its safety. Therefore, timely detection of abnormal deformation signals in buildings is essential for the protection of architectural heritage. Spaceborne synthetic aperture radar interferometry (InSAR) can detect slight displacements over large areas. However, relying solely on annual mean velocity maps derived from InSAR may not accurately assess the stability of ancient buildings. In this study, we developed a framework that evaluates the stability of individual buildings by integrating the InSAR displacements with building footprints. Vertical and rotational deformations, along with the temporal evolution of these deformations, are combined to generate the results for building stability assessment. We used 74 TerraSAR-X images captured from August 2017 to November 2019 to evaluate the stability of Jianchuan Ancient Town, a renowned National Historical and Cultural City in China. The displacement result suggests that the majority of Jianchuan Ancient Town remains stable, with over 93% of coherent points (CTs) displaying displacement velocities ranging from −5 to 5 mm/yr. Out of the 1,891 buildings in Jianchuan Ancient Town, 1404 are considered stable, 352 are of moderate stability, and 12 are deemed unstable. This study showed the potential of InSAR applications in assessing the stability of architectural heritages, emphasizing its crucial role in heritage preservation and management.
Analyzing spatiotemporal features of Suzhou's old canal city: an optimized composite space syntax model based on multifaceted historical-modern data
Authors: Xia Rong , Genovese Paolo Vincenzo , Li Zhixing , Zhao Yafei 
Published: November 2024

Abstract
Rivers and road systems play crucial roles in urban development and in shaping the vitality of cities. The present study focuses on the spatiotemporal development patterns of canal cities. Taking Suzhou as an example, employing various spatial measurement methods combined with multidimensional spatiotemporal data, it clearly demonstrates the urban morphological patterns and societal characteristics related to the road and river network systems at different stages of urban development. Utilizing data extracted from historical and modern maps of Suzhou and employing the YOLO (You Only Look Once) algorithm, this study establishes a spatiotemporal dataset for Suzhou's ancient city, a representative Chinese canal city. An optimized space syntax algorithm for public service facilities, utilizing Python library like Geopandas, Numpy, is proposed to analyze the river and road system's impact on historical development and urban morphology. With multiple spatial econometric models applied to maps from various periods, this research explores the following findings: (1) By controlling rivers as a variable, it quantitatively confirms that rivers were crucial components of urban systems in ancient cities, playing a significant role in urban development and activities, though gradually overlooked in modern times. (2) Public service facilities of different types demonstrate patterns of Accessibility and Integration within the river-road system across various periods. (3) Changes in the distribution of public service facilities correspond to phased shifts in the center of Suzhou’s ancient city, mutually validating the authenticity of realistic paintings, historical maps, and the methodologies used in this study. This study emphasizes a broader historical and spatiotemporal perspective, augmented by quantitative research methods. It investigates the distribution and developmental characteristics of various types of public service facilities across different periods. The research aim is to understand the impact of river and road systems on urban development, as well as the morphological and social changes in historical cities that arise from urban activities.
A survey of graph convolutional networks (GCNs) in FPGA-based accelerators
Authors: Procaccini Marco , Sahebi Amin , Giorgi Roberto 
Published: November 2024

AbstractThis survey overviews recent Graph Convolutional Networks (GCN) advancements, highlighting their growing significance across various tasks and applications. It underscores the need for efficient hardware architectures to support the widespread adoption and development of GCNs, particularly focusing on platforms like FPGAs known for their performance and energy efficiency. This survey also outlines the challenges in deploying GCNs on hardware accelerators and discusses recent efforts to enhance efficiency. It encompasses a detailed review of the mathematical background of GCNs behind inference and training, a comprehensive review of recent works and architectures, and a discussion on performance considerations and future directions.
Disciplinary differences in undergraduate students' engagement with generative artificial intelligence
Authors: Qu Yao , Tan Michelle Xin Yi , Wang Jue 
Published: November 2024

AbstractThe rapid development of generative artificial intelligence (GenAI) technologies has sparked widespread discussions about their potential applications in higher education. However, little is known about how students from various disciplines engage with GenAI tools. This study explores undergraduate students' GenAI knowledge, usage intentions, and task-specific engagement across academic disciplines. Using a disciplinary categorization framework, we examine how the hard/soft and pure/applied dimensions relate to students' interactions with GenAI. We surveyed 193 undergraduates from diverse disciplines at a university in Singapore. The questionnaire assessed students' GenAI knowledge, usage intentions, and engagement with GenAI for cognitive and routine tasks against their disciplinary background. The results indicate substantial disciplinary disparities in the level of engagement of students with GenAI. Compared to pure fields, applied fields (both hard and soft) consistently exhibit higher levels of GenAI knowledge and utilization intentions. Furthermore, the engagement of GenAI in routine tasks is relatively consistent across disciplines; however, there are substantial disparities in cognitive tasks, with applied fields exhibiting higher engagement. These results suggest that the practical orientation of applied fields drives GenAI adoption and utilization in academic settings. The study emphasizes considering disciplinary differences to better integrate GenAI into higher education and calls for tailored approaches that align with each field's unique epistemological and methodological traditions to balance GenAI's practical benefits with the preservation of core disciplinary knowledge and skills.
Investigation of co-seismic stress and aftershock distribution along the Sumatra–Andaman subduction zone
Authors: Sukrungsri Santawat , Khamsiri Sutthikan , Pailoplee Santi 
Published: November 2024

AbstractThis study aimed to investigate co-seismic stress and aftershock distribution along the Sumatra–Andaman subduction zone (SASZ). The fault parameters of six major earthquakes with an M ≥ 7 that occurred during 2010–2022 along the SASZ, were utilized to determine the Coulomb stress change using numerical modeling techniques calculated on the receiver faults with similar focal mechanisms of the mainshock, strike-slip, thrust, and normal faulting, respectively. The earthquake events were then classified to analyze the aftershocks of major earthquakes in the area. These aftershocks were mapped in order to determine the relationship between the aftershock distribution and the areas of increased or decreased stress. The relationship between the co-seismic stress and distribution of aftershocks in the SASZ was found to mainly depend on the focal mechanism of major earthquakes and the type of receiver fault used for calculation. After a major earthquake in the SASZ, there are two possible patterns that most aftershocks will be generated from in the areas of increased stress. First, a major earthquake is a type of thrust fault calculated on the receiver fault using the focal mechanism of the mainshock. Second, a major earthquake is a type of strike-slip fault calculated on the receiver fault with an optimum-oriented strike-slip fault. This relationship is likely to represent the specific pattern of the seismotectonic stress in the SASZ that can be used to evaluate the risk areas of aftershocks after a major earthquake has occurred. Furthermore, two earthquake events with large magnitudes were generated following the respective major earthquake in the SASZ that were located around the areas of increased stress, indicating that these two earthquake events were likely triggered in areas of increased stress following the respective major earthquake. Therefore, this study concluded that after a major earthquake occurrence in the SASZ, the areas of increased stress have a higher risk of generating both a large number of aftershocks and a new large-magnitude mainshock event. The investigation of co-seismic stress is very important to estimate areas of increased stress after a major earthquake, as this can be useful for monitoring both earthquake and tsunami hazards in the area.
Impact of cable lock distribution on firearm securement after emergent mental health evaluation: a randomized controlled trial
Authors: Ketabchi Bijan , Gittelman Michael A. , Zhang Yin , Pomerantz Wendy J. 
Published: November 2024

Abstract
Background
Suicide-related presentations to pediatric emergency departments (PED) have increased in recent years. PED providers have the opportunity to reduce suicide risk by counseling on restricting access to lethal means. Supplementing lethal means counseling (LMC) with safety device distribution is effective in improving home safety practices. Data on PED-based LMC in high-risk patient populations is limited. The objective of this study was to determine if caregivers of children presenting to PED for mental health evaluation were more likely to secure all household firearms if given cable-style gun locks in addition to LMC.

Methods
In this randomized controlled trial, caregivers completed a survey regarding storage practices of firearms and medication in the home. Participants were randomized to receive LMC (control) or LMC plus 2 cable-style gun locks (intervention). Follow-up survey was distributed 1 month after encounter. Primary outcome was proportion of households reporting all household firearms secured at follow-up. Secondary outcomes included: removal of lethal means from the home, purchase of additional safety devices, use of PED-provided locks (intervention only), and acceptability of PED-based LMC.

Results
Two hundred participants were enrolled and randomized. Comparable portions of study groups completed follow-up surveys. Control and intervention arms had similar proportions of households reporting all firearms secured at baseline (89.9% vs. 82.2%, p = 0.209) and follow-up (97.1% vs. 98.5%, p = 0.96), respectively. Other safety behaviors such as removal of firearms (17.6% vs. 11.8%, p = 0.732), removal of medication (19.1% vs. 13.2%, p = 0.361), and purchase of additional safety devices (66.2% vs. 61.8%, p = 0.721) were also alike between the two groups. Both groups held favorable views of PED-based counseling. Within the intervention group, 70% reported use of provided locks. Preference for a different style of securement device was the most cited reason among those not using PED-provided locks.

Conclusions
PED-based LMC is a favorably-viewed, effective tool for improving home safety practices in families of high-risk children. Provision of cable-style gun locks did not improve rate of firearm securement compared LMC alone—likely due to high baseline rates of firearm securement and preference for different style of lock among non-utilizers.

Clinical Trial Registration
ID: NCT05568901. Clinicaltrials.gov. https://clinicaltrials.gov/. Retrospectively registered October 6, 2022. First participant enrollment: June 28, 2021.
Predicting first-line VEGFR-TKI resistance and survival in metastatic clear cell renal cell carcinoma using a clinical-radiomic nomogram
Authors: Wang Yichen , Zhang Xinxin , Wang Sicong , Shi Hongzhe , Zhao Xinming , Chen Yan 
Published: November 2024

Abstract
Background
This study aims to construct predicting models using radiomic and clinical features in predicting first-line vascular endothelial growth factor receptor-tyrosine kinase inhibitor (VEGFR-TKI) early resistance in metastatic clear cell renal cell carcinoma (mccRCC) patients. We also aim to explore the correlation of predicting models with short and long-term survival of mccRCC patients.

Materials and methods
In this retrospective study, 110 mccRCC patients from 2009 to 2019 were included and assigned into training and test sets. Radiomic features were extracted from tumor 3D-ROI of baseline enhanced CT images. Radiomic features were selected by Lasso method to construct a radiomic score. A combined nomogram was established using the combination of radiomic score and clinical factors. The discriminative abilities of the radiomic, clinical and combined nomogram were quantified using ROC curve. Cox regression analysis was used to test the correlation of nomogram score with progression-free survival (PFS) and overall survival (OS). PFS and OS were compared between different risk groups by log-rank test.

Results
The radiomic, clinical and combined nomogram demonstrated AUCs of 0.81, 0.75, and 0.83 in training set; 0.79, 0.77, and 0.88 in test set. Nomogram score ≥ 1.18 was an independent prognostic factor of PFS (HR 0.22 (0.10, 0.47), p < 0.001) and OS (HR 0.38 (0.20, 0.71), p = 0.002), in training set. PFS in low-risk group were significantly longer than high-risk group in training (p < 0.001) and test (p < 0.001) set, respectively. OS in low-risk group were significantly longer than high-risk group in training (p = 0.003) and test (p = 0.009) set, respectively.

Conclusion
A nomogram combining baseline radiomic signature and clinical factors helped detecting first-line VEGFR-TKI early resistance and predicting short and long-term prognosis in mccRCC patients.
Assessing the intracranial metabolic score as a novel prognostic tool in primary CNS lymphoma with end of induction-chemotherapy 18F-FDG PET/CT and PET/MR
Authors: Mo Yiwen , Li Yongjiang , Huang Yuqian , Chen Mingshi , Zhou Chao , Li Xinling , Wei Yuan , Li Ruping , Fan Wei , Zhang Xu 
Published: November 2024

Abstract
Background
The metabolic response of primary central nervous system lymphoma (PCNSL) patients has yet to be evaluated. This study aimed to assess the prognostic value of a novel scoring scale, the intracranial metabolic score (IMS), in PCNSL patients receiving end-of-therapy 18F-FDG PET/CT (EOT-PCT) and PET/MR (EOT-PMR).

Methods
The IMS was determined based on the metabolism of normal intracranial structures, including gray matter, white matter, and cerebrospinal fluid. The EOT-PCT cohort was evaluated using the IMS and commonly used Deauville score (DS). Another cohort of patients who underwent the EOT-PMR was used to validate the accuracy of the IMS.

Results
In total, 83 patients were included in the study (38 in PET/CT cohort, and 45 in PET/MR cohort). The area under the curve (AUC) values of the IMS for predicting PFS and OS were superior to those of the DS. When patients in the PET/CT cohort were stratified into five groups (respectively labeled IMS 1–5), three groups (IMS1-2, IMS 3–4, and IMS 5), or two groups (IMS1-3 and IMS4-5; IMS 1–4 and IMS 5), a higher IMS score was significantly correlated with poorer PFS and OS (p < 0.001). Similar results were observed for PFS in the PET/MR cohort (p < 0.001). The IMS and DS scale were found to be independent prognostic indicators for PFS and OS in the PET/CT cohort, and the IMS was identified as the sole independent prognostic indicator for PFS in the PET/MR cohort.

Conclusion
The IMS as a novel and effective prognostic tool for PCNSL patients, showing superior predictive value for patients’ outcomes compared to the DS when assessed with EOT-PET scans.
Compatibility of hypokalaemia caused by low-dose prednisolone plus abiraterone acetate therapy for metastatic castration-resistant prostate cancer
Authors: Torii Shota , Torii-Goto Aya , Tanizawa Tamaki , Sakakibara Takashi , Oguri Ryosuke , Nagase Haruka , Nakao Yuri , Hirashita Tomoyuki , Tanaka Kuniaki , Takimoto Norio , Hayashi Takahiro 
Published: November 2024

Abstract
Background
This study aimed to investigate the relationship between low-dose prednisolone (PSL) and the incidence of hypokalaemia at abiraterone acetate (abiraterone) plus PSL combination therapy targeting Japanese patients with metastatic castration-resistant prostate cancer (mCRPC).

Methods
This retrospective observational study included 153 Japanese patients treated with abiraterone and PSL for mCRPC at Kariya Toyota General Hospital and Gifu General Medical Center between September 2014 and October 2022. The incidence of grade ≥ 2 hypokalaemia as well as serum potassium level variations and the continuous combination therapy duration were compared between the low-dose (5 mg/day of PSL) and the standard-dose (10 mg/day of PSL) groups.

Results
This study included 153 patient of which 95 were matched to establish the analysis population. The low-dose and the standard-dose groups consisted of 13 and 82 patients, respectively. No significant difference in the incidence of grade ≥ 2 hypokalaemia was observed between the two groups [15.4% (2/13 patients) in the low-dose group and 12.2% (10/82 patients) in the standard-dose group, P = 0.667]. The low-dose group exhibited a decrease in serum potassium levels from 4.63 on day − 7 − 0 to 4.16 mmol/L on day 84 ± 10 (n = 7, P = 0.066), and serum potassium levels from day − 7 − 0 to 84 ± 10 in the low-dose group appeared to be great in the standard-dose group (n = 37, P = 0.475). The Kaplan–Meier curves for continuity of abiraterone and PSL therapy were not significantly different between the low-dose group (n = 13) and standard-dose group (n = 82, P = 0.427).

Conclusion
Combination therapy with abiraterone and 5 mg/day of PSL in Japanese patients with mCRPC did not change the incidence of grade ≥ 2 hypokalaemia. However, although not significant, 5 mg/day of PSL demonstrated a decreasing trend in serum potassium levels with a larger degree of change than that of 10 mg/day of PSL. Therefore, the combination of abiraterone and 5 mg/day PSL can be administered to Japanese patients with mCRPC. The patients must be monitored for hypokalaemia through measurement of serum potassium levels and observation of subjective symptoms such as muscle weakness, convulsion etc. In addition, the doctor or the pharmacist must explain these symptoms to the patient and instruct them to consult their medical staff immediately in the event of development of such symptoms.
Left-sided portal hypertension caused by a solid pseudopapillary neoplasm of pancreas tail: a pediatric case report
Authors: Sihnkai Toko , Masumoto Kouji , Sanmoto Yohei , Kawami Akio , Ishikawa Miki , Fujii Shunsuke , Saida Tsukasa , Ishiguro Toshitaka , Sakamoto Noriaki 
Published: November 2024

Abstract
Background
Solid pseudopapillary neoplasm (SPN) is a low-grade malignant tumor that occurs in 60% of all pediatric pancreas tumors. Radical tumor resection is essential; however, spleen preservation is also crucial to prevent overwhelming post-splenectomy infection. In contrast, spleen preservation is not always possible, because left-sided portal hypertension (LSPH) can cause splenic vein stenosis or occlusion induced by pancreatic tumor. We herein report on a pediatric patient of LSPH due to SPN in the pancreatic tail.

Case presentation
A 12-year-old girl was admitted to our hospital with left upper quadrant abdominal pain. A solid mass was palpated in the left costal region. The patient showed slight anemia (Hb: 11.8 g/dL) and elevation of inflammatory reaction (CRP: 5.98 mg/dL) without positive tumor markers. A radiological examination revealed that a 9 cm-sized mass with hemorrhagic necrosis in the pancreatic tail. Splenic venous flow was not detected and collateral draining into the left gastric vein and left renal veins were developed with splenomegaly. LSPH was involved at the time of diagnosis. The tumor was diagnosed with SPN, hence tumor resection with spleen preservation was performed. Six months after surgery, the patient developed a left quadrant abdominal pain that worsened during exercise. There was no improvement of splenic venous flow and splenomegaly. LSPH remained with splenomegaly, which possibly triggered the patient’s abdominal pain. The patient underwent splenectomy 9 months after the tumor resection. After the splenectomy, the patient’s abdominal pain disappeared without any recurrence 8-year post-surgery.

Conclusions
LSPH has not been a major focus in previous SPN pediatric patients, although most symptomatic LSPH patients required splenectomy. Careful post-operative observation for LSPH is important for pediatric SPN patients.
Supplementation of glutamine in a short-term boar semen extender during 17°C holding time enhances post-thaw sperm quality for cryopreservation
Authors: Nuntapaitoon Morakot , Tummaruk Padet , Suwimonteerabutr Junpen 
Published: November 2024

Abstract
Background
Glutamine is a nonessential amino acid and the most abundant amino acid found in the seminal plasma and sperm-rich fraction of boar semen. Glutamine plays an important role in enhancing glutathione (GSH) synthesis. It acts as an effective antioxidant in semen and provides intracellular defense to sperm against oxidative stress. This study aimed to improve the quality of frozen-thawed boar semen by using glutamine supplementation in a short-term semen extender during the holding time at 17 °C before cryopreservation.

Results
The results indicate that the total motility, progressive motility, LIN, STR, and WOB were the highest in the 20 mM supplementation group at the 2 h timepoint after thawing. Thus, the optimal concentration for glutamine supplementation in short-term boar semen extender during the holding time at 17 °C was 20 mM. Interestingly, at all of the time points after thawing, 20 mM glutamine supplementation exhibited the highest level of sperm viability and membrane integrity when compared to the CONTROL (0 mM) and other experimental dilution groups. Moreover, the acrosome integrity, mitochondrial activity, and capacitation status (F pattern) were significantly greater in the 20 mM supplementation group than the other groups at the 2 h timepoint after thawing.

Conclusion
Supplementation of glutamine at a concentration of 20 mM in a short-term semen extender (Bio Pig®) during the 17 °C holding time before cryopreservation, which had a standard freezing extender (9.0% glycerol and 1.9% Equex paste), could enhance the post-thaw sperm motility and quality parameters of cryopreservation.