bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization, Categorization, and 5-Year Mortality of Medicine High Utilizer Inpatients
Authors: Dastidar Joyeeta G. , Jiang Min 
Published: May 2018

Background: Patients who are frequently admitted to Medicine inpatient services comprise a distinct subset of readmitted patients about whom not much is known. Objective: We sought to characterize this group including mortality rates, with the goal of better understanding this population. Design: Observational study of frequently hospitalized patients defined as 4 or more admissions over a 6-month period, with hospitalization defined as nonelective admission to the hospital. Setting: Single large academic medical center. Patients: Adult inpatients on general medicine and medicine subspecialty services. Measurements: The number of nonelective medicine hospitalizations, age, clinical conditions and comorbidities, calculation of an age-adjusted Charlson Comorbidity Index (CCI), outpatient and emergency department visits, length of stay, costs of hospitalization, and mortality over a 5-year period. Descriptive statistics were used to characterize variables of interest. Results: We identified 153 patients with a total of 781 nonelective hospitalizations, totaling greater than 4000 hospital days and with charges of approximately US$9 million during the 6 months. Nearly all had insurance coverage and good outpatient follow-up (median of 7 appointments over the 6-month study period). Only 14% of those admissions qualified for observation status. Over 40% of patients had comorbid mental health disease or chronic narcotic dependence. Twenty-nine percent of patients died within 1 year; 50% were dead within 5 years. Age-adjusted CCI scores ranged annually from 3.00 to 3.58 among surviving patients versus 4.31 to 6.60 among deceased patients. Conclusions: These findings point to distinct groups of patients who are frequently hospitalized, and therefore would benefit from tailored management strategies: Those with progression of end-stage disease comprised one-third of the group and targeting that subset with palliative care referrals could help decrease readmission rates. Those with recurrent exacerbations of a chronic medical condition could be managed through telemanagement programs. Those with exacerbations of chronic pain could be addressed through collaboration with pain management specialists. Individualized care management plans may be useful for all, especially the latter two groups. Based on differences between survivors and deceased patients, an age-adjusted CCI score of 4 or 5 could be valuable sensitive or specific cutoffs, respectively, for predicting those who would benefit most from palliative care consultation regarding end-of-life goals and management.
Clinical Comparison of Scapular, Fibular, and Iliac Crest Osseal Free Flaps in Maxillofacial Reconstructions
Authors: Wilkman T. , Husso A. , Lassus P. 
Published: May 2018

Background and Aims: This study compared the three most used composite flaps in maxillofacial reconstructions in our institute. Patients and Methods: Between 2000 and 2012, a total of 163 patients with mandibular, maxillary, and orbital defects received either scapular, fibular, or iliac crest osseal reconstructions in Helsinki University Hospital, Departments of Plastic Surgery and Maxillofacial Surgery. Data regarding the patient demographics, complications, and outcomes were analyzed. Results: There were 92 deep circumflex iliac artery flaps (56%), followed by 42 scapular (26%) and 29 fibular flaps (18%). The rate of flap loss was the highest in the deep circumflex iliac artery group (p = 0.001). Reconstructions using fibula were fastest (p = 0.001) and had lowest perioperative blood loss (p = 0.013). There were no significant differences in the number of early or late complications between the flaps, but donor site complications were more severe in deep circumflex iliac artery. Osteotomies as well as dental implants were safely performed in all flaps with equal results. Conclusion: All three flaps of this study can be performed with awareness of the deep circumflex iliac artery flap being the least reliable alternative. The knowledge of the advantages and disadvantages of several osseal-free flap alternatives is beneficial in selecting the best suitable method for each individual patient requiring maxillofacial osseal reconstruction.
On Rationality
Authors: Craske James , Loschmann Janis 
Published: May 2018

Rationality is an enduring topic of interest across the disciplines and has become even more so, given the current crises that are unfolding in our society. The four books reviewed here, which are written by academics working in economics, political science, political theory and philosophy, provide an interdisciplinary engagement with the idea of rationality and the way it has shaped the institutional frameworks and global political economy of our time. Rational choice theory has certainly proved to be a useful analytic tool in certain contexts, and instrumental reason has been a key tenet of human progress in several periods of history, including the industrial revolution and the modernity that emerged in the nineteenth century. Given the complexity of our current challenges, however, is it time to ask whether this paradigm might be better complemented by more holistic and heterodox approaches? Hindmoor A and Taylor TY (2015) Rational Choice (Political Analysis), 2nd edn. London; New York: Palgrave Macmillan. Massumi (2015) The Power at the End of the Economy. Durham: Duke University Press. Brown (2015) Undoing the Demos: Neoliberalism’s Stealth Revolution. New York: Zone Books. Ludovisi SG (ed.) (2015) Critical Theory and the Challenge of Praxis: Beyond Reification. Farnham; Burlington, VT: Ashgate.
The perceptions of nurses, patients and family members regarding nurses' empathetic behaviours towards patients suffering from cancer: a descriptive qualitative study
Authors: Ashouri Elaheh , Taleghani Fariba , Memarzadeh Mehrdad , Saburi Morteza , Babashahi Fatemeh 
Published: May 2018

Background Although evidence suggests that empathic behaviour is an essential component in nursing care that affects the psychological distress experienced by cancer patients, it remains a neglected issue in nursing in Iran. Methods: This study was conducted on 33 participants selected through purposive sampling. Data were collected using in-depth interviews and were then analysed using qualitative content analysis with an inductive approach. Findings: Three categories of data thus emerged, comprising: (a) empathetic attention; (b) empathetic presence; and (c) the facilitators of empathetic behaviour. Conclusions: The findings can help oncology nurses provide more empathetic care to patients and their family members.
Perineal pain: Think beyond gynaecological reasons
Authors: Gupta Neha , Nigam Vishal 
Published: May 2018

Introduction: Perineal pain is multifactorial in nature. Gynaecological consultation is the first point of contact in females with perineal pain for diagnosis and treatment. Case description: Three females above 60 years presented with non-radiating perineal pain and bladder disturbance. Magnetic resonance imaging revealed severe L5 S1 dural compression, which was released by posterior laminectomy. Patients felt relief in perineal pain, though bladder symptoms persisted for several months. Conclusion: Sacral roots compression leading to pain along pudendal nerve distribution may present with cauda equina symptoms with pain radiating to legs. Awareness of this condition can prevent the delay and lead to better prognosis after the surgery.
Graft-versus-host disease in recipients of male unrelated donor compared with parous female sibling donor transplants
Authors: Kumar Anita J. , Kim Soyoung , Hemmer Michael T. , Arora Mukta , Spellman Stephen R. , Pidala Joseph A. , Couriel Daniel R. , Alousi Amin M. , Aljurf Mahmoud D. , Cahn Jean-Yves , Cairo Mitchell S. , Cutler Corey S. , Farhan Shatha , Gergis Usama , Hale Gregory A. , Hashmi Shahrukh K. , Inamoto Yoshihiro , Kamble Rammurti T. , Kharfan-Dabaja Mohamed A. , MacMillan Margaret L. , Marks David I. , Nakasone Hideki , Norkin Maxim , Qayed Muna , Ringden Olle , Schouten Harry C. , Schultz Kirk R. , Solh Melhem M. , Teshima Takanori , Urbano-Ispizua Alvaro , Verdonck Leo F. , Gale Robert Peter , Hamilton Betty K. , Majhail Navneet S. , Loren Alison W. 
Published: May 2018

Key Points
Compared with parous female sibling donors, male URDs confer more aGVHD in all patients and more cGVHD in females. There was no difference in survival, relapse, or transplant mortality between recipients of parous female sibling or male URD grafts.
Prognostic significance of bone marrow abnormalities in the appendicular skeleton of patients with multiple myeloma
Authors: Matsue Kosei , Kobayashi Hiroki , Matsue Yuya , Abe Yoshiaki , Narita Kentaro , Kitadate Akihiro , Takeuchi Masami 
Published: May 2018

Key Points
Bone marrow abnormalities were detected in the AS of 196 consecutive symptomatic patients with MM. Medullary abnormalities in the AS were associated with a poor prognosis, independent of other clinical parameters.
Analysis of MCFD2- and LMAN1-deficient mice demonstrates distinct functions in vivo
Authors: Zhu Min , Zheng Chunlei , Wei Wei , Everett Lesley , Ginsburg David , Zhang Bin 
Published: May 2018

Key Points
LMAN1 and MCFD2 have distinct functions and are required for ER-to-Golgi transport of FV, FVIII, and α1-antitrypsin. An alternative transport pathway is responsible for remaining FV/FVIII secretion in LMAN1/MCFD2-deficient mice.
The use of sub-epidermal moisture measurement in predicting blanching erythema in jaundice patients
Authors: Park Seungmi , Kim Chul-Gyu , Ko Ji Woon 
Published: May 2018

Objective:To investigate the relationship between sub-epidermal moisture (SEM) and visual skin assessment (VSA) in pressure ulcers (PU) patients with jaundice in Korea.Method:This is a longitudinal observational study. Data was collected by a wound care nurse, at a tertiary hospital, for six weeks beginning in June 2013. Once a week for the six weeks, the nurse assessed VSA and measured SEM, for each subject, on seven anatomical sites (both buttocks, both ischial tuberosities, both trochanters, and the sacral coccyx), using a NOVA Petite dermal phase meter for SEM. The measurements ranged from 0 to 999, and higher SEM indicates higher water content in the tissue.Results:There were 22 adults participated in the study. The SEMs in category I PU were significantly higher than those in patients who had no injury, or blanching erythema. The SEM difference between category I PU and either blanching erythema or no injury was more than 60 points at the sacral coccyx, and the difference between blanching erythema and no PU was more than 100 points at the trochanters. After the covariates were adjusted for, the odds ratios (ORs) for blanching erythema were statistically significant. The ORs for blanching erythema versus normal skin was 1.016 higher than the concurrent SEMs. Also, The ORs of 1-point concurrent SEMs for blanching erythema versus normal skin at Sacral coccyx, right and left ischial tuberosity and left trochanter were 1.015, 1.128, 1.137 and 1.051 respectively (p<0.05).Conclusion:SEM was associated with concurrent early skin damage, specifically blanching erythema with jaundice. Therefore, SEM may be used to predict early skin damage in patients with jaundice in clinical nursing for effective PU prevention and management.
As ambiguidades nos atos performativos dos rapazes negros estudantes: possibilidades para uma educação libertadora
Authors: Messeder Suely Aldir , França Elisete Santana da Cruz , Lima Maria Nazaré Mota de 
Published: May 2018

O artigo escrito por três mulheres pesquisadoras, educadoras e negras buscou compreender como os jovens negros reinterpretam as brincadeiras infantis na construção de suas masculinidades, mediante a
reconstrução das narrativas destes rapazes, no âmbito de um grupo focal desenvolvido no contexto escolar soteropolitano. Na analise destas narrativas foi possível identificar que a brincadeira de luta ou a briga é mais praticada por eles, embora tivessem elencado o pega-pega, futebol, rasteira, handebol, esconde-esconde, os desenhos animados animes, papai e mamãe. Na interpretação sobre a luta reportou-se a outras dimensões que se coloca na ambiguidade entre o natural e cultural (aprendizado), daí a possibilidade de apostar nas zonas dos interstícios, enfrentando a moralidade da maioria, tendo como conteúdo a ser trabalhado as diversidades das próprias vivências. Embora, o foco de análise centra-se nas narrativas destas vivências, foi considerado as
lógicas de opressão da desigualdade de classe, do racismo, do sexismo e da heteronormatividade estruturadas e estruturantes destas vivências.
EVALUACIÓN DEL ESTADO NUTRICIONAL Y METABOLISMO HEPÁTICO EN RATAS MACHO EXPUESTAS CRÓNICAMENTE A LA INGESTA DE GLUTAMATO MONOSÓDICO
Authors: Contini María del Carmen Ada , Millen Néstor , Benmelej Adriana , Fabro Ana Patricia , Mahieu Stella Teresita 
Published: May 2018

La ingesta de GMS (glutamato monosódico) se ha relacionado con múltiples acciones post-ingesta por eso investigamos los efectos de la ingesta crónica. Trabajamos en ratas Wistar machos divididas en dos grupos: control y GMS. El consumo de GMS aumentó el peso corporal, el IMC, la circunferencia abdominal y la grasa retroperitoneal. Las ratas presentaron alteraciones en la tolerancia a la glucosa, hiperinsulinemia con resistencia a la insulina y dislipidemia. Los niveles de triglicéridos y de glucógeno hepáticos fueron significativamente mayores. GMS no afectó significativamente la peroxidación lipídica hepática. El aumento de las actividades de GPx y GR fue acompañado con una disminución en la de SOD, sin cambios en la de CAT. La valoración histológica mostró que el GMS induce diferentes grados de degeneración, inflamación e hialinización en hepatocitos, con pocos focos de necrosis. La ingesta de GMS ejerció efectos sobre el metabolismo de los carbohidratos y lípidos, sin cambios importantes en el estado oxidativo pero con inducción de alteraciones de la histología hepática.
Comportamiento de enzimas antioxidantes glutatión peroxidasa (GPx) y superoxido dismutasa (SOD) en el musculo cardíaco de ratas dislipémicas insulino resistentes. Estudio preliminar.
Authors: Oliva María E. , Creus Agustina , Bolzon de Lombardo Yolando , Chicco Adriana 
Published: May 2018

El objetivo del trabajo fue analizar en musculo cardiaco el efecto de la administración crónica de dieta rica en sacarosa (DRS) sobre el comportamiento de algunas enzimas antioxidantes y a nivel plasmático la peroxidación lipídica y grupos carbonilos en proteínas como marcadores de daño oxidativo, algunas citoquinas inflamatorias y la presión arterial. Se utilizaron ratas macho Wistar con un peso inicial de 180 g. Luego de una semana de aclimatación los animales fueron divididos aleatoriamente en dos grupos. El grupo control recibió una dieta semisintética (% en peso: almidón: 62,5, aceite de maíz: 7 y proteínas: 18). El grupo DRS recibió la misma dieta semisintética donde la sacarosa sustituyó al almidón como fuente de hidratos de carbono. Los animales de ambos grupos fueron alimentados por 32 semanas. Los resultados alcanzados demuestran que los animales alimentados con DRS presentan: a- diminución de las actividades enzimáticas glutatión peroxidasa (GPx) y superoxido dismutasa (SOD); b- aumento significativo de los mediadores inflamatorios IL-6 y TNFα plasmáticos; c- incremento en la peroxidación lipídica y en los grupos carbonilos en proteínas como marcador de daño oxidativo. Estos efectos se acompañaron de dislipemia, moderada hiperglucemia, adiposidad visceral e hipertensión.
Responsabilidad social y cultura: un estudio fenomenográfico desde el punto de vista del liderazgo en una empresa de ingeniería
Authors: De Castro Seixas Maria Augusta , Perez Peña Miguel Angel , Paiva de Andrade Emmanuel , Cândido João Carlos , Rodrigues Souza de Brito Costa Marcelo 
Published: May 2018

Los estudios sobre cultura organizacional destacan a los líderes como los actores clave para la creación o reconstrucción de una forma de pensar y actuar de la empresa. El presente estudio escogió este segmento para investigar sus percepciones, cómo son las vivencias y en qué contexto experimentan la concepción de responsabilidad social (RS) como parte del trabajo en una empresa de ingeniería. Se utilizaron los procedimientos metodológicos de la fenomenografía para crear y analizar las categorías descriptivas que contribuyen a la comprensión del fenómeno de la responsabilidad social en la empresa. La muestra incluyó 20 entrevistas semiestructuradas. El análisis de datos ha permitido identificar que los líderes tienen diferentes niveles de percepción y un conocimiento fragmentado sobre el concepto de responsabilidad social, y esto se refleja en sus decisiones.Al permitir la identificación de las diversas concepciones de un mismo fenómeno y el contexto relacionado con él, este método cualitativo fue importante para identificar la presencia de las responsabilidades sociales para el día a día del negocio de la empresa y cómo este fenómeno está internalizado en la cultura de la organización, es decir, la forma en que es parte del pensamiento y la actuación de la empresa
El modelo de Cheap Talk: su aporte a la divulgación de la información social y ambiental
Authors: Verón Carmen Stella , Pastor Sandra Patricia 
Published: May 2018

La relación que las empresas construyen con sus grupos de interés queda determinada por sus revelaciones sociales, ambientales y económicas, ya sean voluntarias o de cumplimiento obligatorio y de acuerdo con Gray et ál. (1995) se puede analizar desde tres perspectivas teóricas: la de la decisión–utilidad, la teoría económica y la teoría sociopolítica. Estos enfoques teóricos coinciden en la importancia de la estrategia de divulgación. Con un enfoque diferente, el modelo conocido como cheap talk, busca determinar el efecto de la información no vinculante en el comportamiento de las partes vinculadas a una negociación. El cheap talk hace referencia a una serie de mensajes sin costo, no vinculantes, y no verificables que sin embargo pueden afectar las creencias del oyente e incidir en sus decisiones. El cuestionamiento sobre la credibilidad de la información contenida en los reportes de responsabilidad social empresaria es un prejuicio que socava su importancia y claramente afecta su desarrollo, a pesar de los instrumentos de verificación y aseguramiento que la profesión contable ha diseñado para contrarrestarla.
Conducción y gerencia en la Oficina de Gestión Judicial Poder Judicial de la Provincia de Santa Fe
Authors: Drago Mariana Jimena 
Published: May 2018

La conducción y la gerencia en las organizaciones del Estado se desarrollan en un ambiente no sólo gerencial sino también político. Por esta razón, la gestión pública es más compleja que la gestión privada. En el sector público hay diversidad de actores involucrados, los intereses son en ocasiones contradictorios, el dirigente debe lograr el consenso en torno a sus proposiciones, las reglas son rigurosas y los resultados no son fáciles de medir.En este contexto y bajo la luz de los diferentes expositores en la materia, en el presente trabajo se analizará la situación actual de la Oficina de Gestión Judicial, perteneciente al Poder Judicial de la Provincia de Santa Fe, y se realizará un informe propositivo para el modelo de gestión en que se desarrolla.
Consumo responsable y sustentable en los jóvenes universitarios de Santa Fe
Authors: Gesualdo Gabriela 
Published: May 2018

Puede caracterizarse a una sociedad consumista como aquella en la que se consume no solo lo necesario para la vida sino lo superfluo; en la que el consumo legitima la política y legitima la economía, y en la que además, las personas miden su éxito y su felicidad en ese consumo (Cortina y Carreras, 2004). En ese contexto, el consumidor responsable es quien, siendo consciente de sus hábitos de consumo, conoce sus derechos como consumidor y elige opciones de productos con menor impacto negativo sobre la sociedad, buscando no sólo su satisfacción personal sino también el interés externo.El análisis del consumo en los jóvenes es incipiente en nuestro país, por lo que en esta tesis se ha focalizado el estudio en los jóvenes universitarios de la ciudad de Santa Fe y definido como problema de investigación sondear el nivel de información y compromiso de los jóvenes respecto del consumo responsable y sustentable. El trabajo empírico se aplicó sobre los jóvenes estudiantes de la UNL, como posibles emprendedores o futuros dirigentes de distintos tipos de organizaciones, teniendo en cuenta que, en forma creciente, las actuales organizaciones requieren profesionales que más allá de contar con su bagaje disciplinar específico —que le permita ejercer eficazmente las funciones propias de su profesión y optimizar su desempeño— sean capaces de comprender la función social de estas organizaciones y su compromiso con el desarrollo sustentable.
A New Control Scheme for Integrating Processes with Inverse Response and Time Delay
Authors: Kumar Medarametla Praveen , Manimozhi M 
Published: May 2018

Abstract
This paper presents a novel technique in designing controller for integrating process with inverse response and time delay. Using Pade’s approximation, the positive zero is approximated to a negative zero by modifying the time delay of process. The polynomial approach is employed for the rearranged process to derive the controller parameters. The tuning parameter is selected based on the value of maximum sensitivity. Set point filtering is employed to reduce the overshoot in servo response. Various bench marking examples are considered to evaluate the proposed method. The evaluation is carried out in terms of various performances.
Effects of Internal Structure on Anisotropic Creep Behavior of Asphalt Mixture Based on User-Defined Three-Dimensional Discrete Element Method
Authors: Zhang Deyu , Ma Tao , Ding Xunhao , Zhang Weiguang , Huang Xiaoming 
Published: May 2018

Abstract
This study investigated the effects of internal structure on the anisotropic creep behavior of asphalt mixture based on user-defined three-dimensional (3-D) micromechanical discrete element method (DEM). A 3-D micromechanical discrete element asphalt mixture composed of coarse aggregates, asphalt mastic, and air voids was modeled by using DEM software called Particle Flow Code in Three Dimensions (PFC3D). Uniaxial creep tests performed on discrete element models of asphalt mixture were conducted by PFC3D. The effects of aggregate orientations, sphericity, and void orientations were investigated. It was indicated that the longer the projected lengths of aggregates were in the loading direction, the more significant the effect on the anisotropic creep behavior of asphalt mixture. The anisotropy effects on the creep behavior of the asphalt mixture became more obvious as the aggregate sphericity decreased. Moreover, applying the load in the long-axis direction of void orientation could result in relatively small creep strain. It is necessary to take into full consideration the effects of internal structures on the anisotropic creep behavior of asphalt mixtures during material design and field construction to improve the pavement performance.