bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Memory of stones”
Authors: Piotrowski Robert , Wróblewska Violetta 
Published: November 2024

Abstract
This article attempts to interpret folk narratives featuring the motif of producing millstones from erratic boulders and their subsequent reuse in new functional contexts. According to our assumptions, in folk narratives originating from the northern regions of Germany and Poland, where these motifs are present, one can find references to the methods of obtaining stone materials characteristic of these areas. These narratives also include information about the occurrence of erratic boulders – consistent with the geomorphology of regions affected by the last glaciation, and residual information regarding the distribution of millstones as well as semi-finished products. Thus, folk narratives can often serve as an interesting point of reference not only for ethnologists and folklorists but also for geologists and geographers.
Le motif de la

Durée Surnaturelle du Temps au Pays des Fées

dans les romans et les lais

de la littérature médiévale
Authors: Lecco Margherita 
Published: November 2024

Résumé
Le motif que Stith Thompson classe comme Supernatural Lapse of Time in Fairyland (Mot. F 377) joue un rôle important dans le répertoire de la fiction médiévale. Il a cependant été peu étudié dans les textes médiévaux français. L’article vise à en donner des exemples peu connus dans les romans arthuriens et les lais du douzième au quatorzième siècle, du Guingamor (et du De Nugis Curialium de Walter Map) à Meraugis de Portlesguez.
“Ti Tiin Itiin”: An Introduction to the Performance Esthetics of the Konkomba Folktale
Authors: Tidorchibe E. Tasun 
Published: November 2024

Abstract
At the sound of the expression, “Ti tiin itiin” (translated as ‘Let us tell stories’), every Konkomba who is familiar with Konkomba storytelling knows that it is time for some traditional entertainment, education, and free psychotherapy, among other things, via oral storytelling. Although storytelling and its benefits have been widely explored, the Konkomba storytelling culture remains largely unexplored. This paper seeks to fill this gap by exploring the oral performance esthetics associated with the art of storytelling among the Konkomba people of Ghana. The paper discusses the key performance structures or elements of the Konkomba folktale, gestures to the culture-specificity of some of these structures, and argues that though oral and seemingly arbitrary, indigenous oral performances such as Konkomba storytelling are well-structured oral verbal arts. The paper further notes that community – and for that matter the audience at a storytelling session – plays an integral part in the composition and performance processes in traditional theaters such as Konkomba storytelling sessions.
But They Still Lived Happily Ever After – or at Least, Happily
Authors: Anjirbag Michelle Anya 
Published: November 2024

Abstract
This paper examines three films that mark Disney’s foray into postmodern fairy-tale narratives to determine if these attempts to move beyond or complicate Disney princess or fairy-tale narratives are successful. Drawing from fairy-tale studies and age studies, it particularly examines how gendered narratives and stereotypes operate within these narrative spaces, looking at the figures of the princess, the godmother, and the stepmother in Enchanted (2007), Godmothered (2020), and Disenchanted (2022). Through this study I aim to discover if Disney’s contemporary postmodern fairy-tale narratives open up more potential for women in various roles as they age, or if they reiterate various age-related gender stereotypes.
Deskription fachlicher Kommunikation – Vorschlag und Beispiel
Authors: Roelcke Thorsten 
Published: November 2024

Zusammenfassung
Modelle fachlicher Kommunikation dienen nicht allein deren theoretischer Konzeption, sondern auch ihrer empirischen Deskription oder ihrer didaktischen bzw. ethischen Evaluation. In dem vorliegenden Beitrag wird anhand des erweiterten Modells fachlicher Kommunikation von Thorsten Roelcke und des Vorworts zu einem einschlägigen Sammelband zur Fachsprachenlinguistik von John Humbley gezeigt, wie ein solches Modell eine systematische Deskription fachlicher Kommunikation ermöglicht.
Advancements in ascorbic acid quantification: from macroscopic analysis to miniaturized nano-sensing for quality control in food and beverage
Authors: Lee Yue Zhen , Ngan Cheng Loong , Low Siew Chun 
Published: November 2024

Abstract
Ascorbic acid (AA) or vitamin C, is vital in food safety, pharmaceutical and biomedical industries. This review discusses recent advancements in biosensors for AA detection. Traditional macro-analysis techniques such as high-performance liquids chromatography (HPLC), and flow injection analysis (FIA) provide accurate measurements but are costly and require specialized handling. Miniaturized nano-sensors are emerging as promising alternatives, offering advantages such as portability, cost effectiveness, and rapid response. This review explores the working principles of these nano-sensors, highlighting colorimetric, fluorometric and electrochemical detection methods. It also outlines the current AA biosensing landscape, detailing strategies to improve selectivity and specificity, including the choice of biorecognition elements and material selection for detection probe synthesis. Emerging nanomaterials and their applicability to support sensing activity are explored. This review serves as a valuable resource, suggesting future research directions to address existing challenges and further advance biosensor technology.
Outcomes of newborns screened for congenital hypothyroidism in Turkey – a single center experience
Authors: Esen Ihsan , Eraslan Nilgun , Okdemir Deniz 
Published: November 2024

Abstract

Objectives
It was aimed to investigate the outcomes of babies referred to a tertiary health center in Turkey for evaluation primary congenital hypothyroidism (CH) through newborn screening.

Methods
The hospital files of 328 newborns who were referred for CH from newborn screening between June 2013 and June 2020 were retrospectively reviewed. The newborns were evaluated with their clinical characteristics at admission, as well as their follow-up data and final diagnoses.

Results
Sixteen (4.9 %) newborns were diagnosed with transient neonatal hyperthyrotropinemia after follow-up. Treatment was initiated in 166 (50.6 %) of the cases with a diagnosis of CH. The median age at initiation of treatment was 17 days (5–69). Treatment was initiated in 88.3 % of the cases in the first month of the life. After at least 3 years of follow-up, 30/120 (20.0 %) of the cases were diagnosed with permanent CH and 11/30 (36.7 %) of them were diagnosed with thyroid dysgenesis. All of the cases who used >37.5 µg per day levothyroxine at the age of 1 or 2 years were diagnosed with permanent CH during their follow-up. For the prediction of transient CH, the sensitivity and specificity of levothyroxine doses of ≤25 µg per day at 1 year of age were calculated as 96.2 and 46.2 %, and for 2 years of age, the sensitivity and specificity were calculated as 97.8 and 65.2 %.

Conclusions
In this cohort, 10 % of all referrals result in permanent CH. Thyroid imaging with ultrasonography and levothyroxine dose during follow-up can be guiding in predicting permanent CH.
Decolonizing the Library: Considering the Movement in the Irish Colonial Contexts
Authors: Cooke-Escapil Louise 
Published: November 2024

Abstract
Decolonization is a concept which has been rapidly gaining traction in the library community, particularly in England, the United States, and Australia. This article addresses the question: “what does decolonizing the library look like in the Irish colonial contexts?” The role which libraries play in reckoning with colonial pasts cannot be understated. This paper will explore what decolonization can look like through Irish libraries both north and south of the border. This will be examined through Irish language revitalization, the presence of oral histories in library collections, and how libraries respond to underserved communities. This study also establishes areas for further research in this nascent field as well as outlining practical steps to implement the concept of decolonizing the library in the Irish contexts. Drawing on qualitative data pulled from interviews this paper will offer the latest information on the Irish library landscape and its relation to the broader decolonization movement. This paper aims to demonstrate the value of using the decolonization framework to address the colonial past which has impacted the way in which the information services function in modern day Ireland and pave the way towards an inclusive and equitable future.
The crystal structure of 1,1,1,2,2,2-hexakis(2-methyl-2-phenylpropyl)distannane,C60H78Sn2
Authors: Shen Yi 
Published: November 2024

Abstract
C60H78Sn2, cubic, Pa3̄ (no. 206), a = 17.621(2) Å, V = 5,472(2) Å3, Z = 4, R

gt
(F) = 0.0214, wR

ref
(F
2) = 0.0600, T = 296 (2) K.
Traço de ansiedade de graduandos de Enfermagem: relações com competência em comunicação interpessoal e características sociodemográficas
Authors: Pires Flávio de Oliveira , Oliveira Leidilândia do Nascimento , Silva Renata de Freitas da , Grilo Adriana Pereira da Silva , Maruxo Harriet Bárbara , Chamon Andrea Regina Marques 
Published: November 2024

Objetivo: correlacionar o traço de ansiedade de graduandos de Enfermagem com a competência em comunicação interpessoal e características sociodemográficas. Métodos: estudo transversal, cujas variáveis principais foram: competência em comunicação, características sociais e traço de ansiedade. A amostra foi composta por 30 participantes, com idade média de 24,3 (± 8,5). Resultados: a correlação entre o traço de ansiedade e competência em comunicação interpessoal foi baixa (p=0,251). Estudantes que trabalham, especialmente na área de enfermagem, apresentaram escores de traço de ansiedade mais altos 62,3 (± 10,3). Na competência em comunicação interpessoal, o domínio de autorrevelação teve o maior escore (15,0); e manejo das interações, o menor (8,0). Conclusão: a correlação entre o traço de ansiedade e a competência em comunicação interpessoal foi baixa, com tendência de aumento nos escores da escala. Estudantes que trabalham, especialmente na área de enfermagem, apresentam escores mais elevados de traço de ansiedade e maior dificuldade em desenvolver empatia. Contribuições para a prática: é importante os estudantes desenvolverem habilidades comunicativas e aprenderem a controlar a ansiedade para se sentirem mais seguros e competentes. Características sociodemográficas como idade, experiência e responsabilidades impactam diretamente essa competência.
APOC1 rs445925 and rs4420638 polymorphic variants as genetic predictors of occlusive peripheral arterial disease of lower extremities
Authors: Zhabin S. N. , Lazarenko V. A. , Azarova Yu. E. , Klesova E. Yu. , Bykanova M. A. , Chernousova S. S. , Bashkatov D. A. , Churnosov M. I. , Solodilova M. A. , Polonikov A. V. 
Published: November 2024

Aim. To study the involvement of APOC1 rs445925 and rs4420638 single nucleotide polymorphisms (SNP) in the development of occlusive peripheral arterial disease (PAD) of lower extremities.Material and methods. The study included 1278 people, including 630 patients with occlusive PAD and 648 relatively healthy individuals. Genotyping of APOC1 rs445925 and rs4420638 SNPs was performed using the MassARRAY-4 genomic mass spectrometer. The analysis of the association of alleles, genotypes, haplotypes and diplotypes with the risk of occlusive PAD was performed using the statistical programs SNPStats, PLINK, v1.9 and STATISTICA 13.3. The adaptive permutation test was used to assess statistical significance of associations (Pperm).Results. The rs445925-A (Pperm=1,0×10-6) and rs4420638-G (Pperm=0,006) alleles, as well as the rs445925-G/A-A/A (Pperm=1,0×10-6) and rs4420638-A/G-G/G (Pperm=0,006) genotypes were associated with an increased risk of occlusive PAD. The rs445925 polymorphism was also associated with the blood cholesterol level in patients with occlusive PAD (Pperm=0,04). The rs445925A-rs4420638A and rs445925A-rs4420638G haplotypes, as well as three APOC1 diplotypes, showed a pronounced relationship with a predisposition to occlusive PAD. In particular, the rs445925G/A×rs4420638A/A (odds ratio (OR) 6,59, 95% confidence interval (CI) 4,20-10,35, P=2,4×10-19) and rs445925G/A×rs4420638A/G (OR 4,24, 95% CI 2,23-8,03, P=2,0×10-6) diplotypes were associated with an increased risk of occlusive PAD. The rs445925G/G×rs4420638A/A diplotype had a protective effect on the disease development (OR 0,26, 95% CI 0,20-0,35, P=1,3×10-20). Associations of haplotypes with the severity of peripheral arterial stenosis of various locations were also revealed (P<0,05).Conclusion. The study results established for the first time that APOC1 rs445925 and rs4420638 polymorphic variants are part of a genetic predisposition to occlusive PAD and have a significant effect on the severity of peripheral arterial stenosis. The molecular mechanisms underlying the identified genotypic associations can affect not only lipid metabolism disorders, but also the proliferation of immunocompetent cells, platelet activation and aggregation processes, inflammation and apoptosis.
Efficacy of P2Y12 receptor inhibitors in myocardial infarction in individuals carrying different CYP2C19 genotypes living in the northern region of Russia
Authors: Vorobyov A. S. , Lifshits G. I. , Zelenskaya E. M. , Batueva K. Yu. , Kovalenko L. V. , Urvantseva I. A. , Donnikov M. Yu. , Poptsova M. S. , Zbirovskaya E. P. , Nikolaev K. Yu. 
Published: November 2024

Aim. To evaluate the efficacy of P2Y12 receptor inhibitors (clopidogrel and ticagrelor) in patients with myocardial infarction (MI) living in the northern region of Russia (Khanty-Mansi Autonomous Okrug — Yugra), depending on the carriage of various CYP2C19 allelic variants.Material and methods. This prospective observational study included 218 patients with acute MI who underwent percutaneous coronary intervention (PCI). The patients also underwent determination of allelic variants of the CYP2C19 gene. Patient were divided into groups receiving clopidogrel (n=164, 75%) and ticagrelor (n=54, 25%). Using biostatistical analysis methods, a comparison of clinical and genetic characteristics was performed, as well as an assessment of the risk of ischemic events between the groups in the long-term (108 months, 9 years) post-infarction period.Results. Reduced (*1/*2, *2/*2, *1/*3) and increased (*1/*17, *17/*17) metabolizer CYP2C19 genotypes, as well as severe comorbidity, are reliable independent predictors of composite outcome (cardiovascular death, recurrent acute coronary syndrome, coronary stent/bypass thrombosis, myocardial revascularization, acute ischemic cerebrovascular accident) during a long-term (9 years) follow-up. The advantages of ticagrelor over clopidogrel in terms of the effect on the incidence of ischemic events in the long-term period were established without a significant difference for bleeding both in the general cohort of patients and among carriers of CYP2C19 allelic variants (*1/*2, *2/*2, *1/*3) and (*1/*17,*17/*17) in patients with MI.Conclusion. Ticagrelor is significantly more effective than clopidogrel in reducing the risk of ischemic events in the general cohort of patients, as well as in carriers of reduced (*1/*2, *2/*2, *1/*3) and increased (*1/*17, *17/*17) metabolizer CYP2C19 genotypes during 9-year follow-up after the index MI.
Rare filamin C variants among patients with hypertrophic cardiomyopathy referred for septal myectomy
Authors: Andreeva S. E. , Gurshchenkov A. V. , Zajcev V. V. , Kozyreva A. A. , Mihaleva A. I. , Murav'ev A. S. , Grebennik V. K. , Mitrofanova L. B. , Gordeev M. L. , Moiseeva O. M. , Kostareva A. A. 
Published: November 2024

Aim. To determine the prevalence and profile of rare variants of the filamin C gene (FLNC) among patients with hypertrophic obstructive cardiomyopathy (HCM) referred for septal myectomy, and to provide a clinical description of HCM occurring with these variants.Material and methods. Ninety-eight adult patients with HCM who underwent septal myectomy underwent genetic testing by next-generation sequencing using a targeted cardiac panel (39-gene panel in 58 patients and 17-gene panel in 40 patients). In patients with rare FLNC variants (with a minor allele frequency <0,01%), the data of anamnesis, echocardiography, electrocardiography, Holter monitoring, and myocardial histological examination were analyzed.Results. Four patients with rare FLNC variants (two men and two women) were identified, which amounted to 4% (Pro1774Ser, Thr1317Pro and His1834Tyr, the latter was detected twice). These variants were missenses and classified as variants of uncertain clinical significance. The FLNC p.Thr1317Pro variant in one patient was combined with a pathogenic variant p.Val606Leu in MYH7 gene. All patients received diagnosis of HCM after age of 40 years. Clinical course was represented by mild symptoms of heart failure and class II stable angina. Episodes of non-sustained ventricular tachycardia, atrial fibrillation or clinically significant conduction block were not registered. One patient with p.His1834Tyr FLNC variant had reverse curve interventricular septum morphology, whereas other patients had predominant hypertrophy of basal segment of interventricular septum. Diastolic dysfunction did not exceed grade 1-2 in all four patients.Conclusion. The clinical characteristics of carriers of rare FLNC variants in our study did not differ from the majority of patients with HCM who underwent septal myectomy. Rare FLNC variants can act as causative or modifying factors of HCM course. Functional and population-based studies using segregation analysis should clarify the pathogenicity of rare FLNC variants.
Identification of poor prognosis predictors in patients with pulmonary embolism
Authors: Kryuchkova N. M. , Nikulina S. Yu. , Chernova A. A. , Alyabyeva A. A. , Maksimov V. N. 
Published: November 2024

Aim. To identify the predictors of poor prognosis in patients with pulmonary embolism (PE).Material and methods. The study included 120 patients with verified PE. The analysis included the clinical evidence collection, paraclinical investigations (including echocardiography) and genetic analysis. Cox regression analysis was used to assess mortality predictors. Statistical data processing was performed using Excel 2019, SPSS Statistica v. 26 (IBM, USA), MedCalc v. 20.104 and JMP Pro 17 (SAS, USA) software.Results. The following independent mortality predictors were identified using multivariate regression analysis: age (odds ratio (OR) 1,051, p=0,0002), prior venous thromboembolism (OR 2,090, p=0,0117), TT genotype of the F13A1 rs5985 polymorphism (OR 2,820, p=0,0427) and anteroposterior right ventricular size (OR 1,043, p=0,0294). Right ventricular wall hypokinesis (OR 5,040, p=0,0285), submassive pulmonary artery involvement (OR 2,714, p=0,0025), prior myocardial infarction (OR 2,839, p=0,0028) and other factors were significantly associated with an increased death risk. Based on these predictors, a prognostic model was developed that allows for effective stratification of the death risk.Conclusion. The predictors identified in the study can be used for risk stratification and optimization of patient management with PE, which can improve the prognosis and treatment outcomes.
Genetic predictors of cardiovascular toxicity in oncohematological patients
Authors: Gimatdinova G. R. , Danilova O. E. , Davydkin I. L. , Milyutkina Yu. S. , Sustretov A. S. , Germanova O. A. 
Published: November 2024

Aim. To identify single nucleotide polymorphisms reliably associated with cardiovascular toxicity in oncohematological patients receiving antitumor immunochemotherapy.Material and methods. For the study, 34 patients with an established diagnosis of non-Hodgkin's B-cell follicular lymphoma were prospectively selected at the Clinic of the Samara State Medical University, who were indicated for antitumor immunochemotherapy according to the R-CHOP protocol. During the follow-up, the patients were divided into 2 following groups: the main group consisted of 12 patients with cardiovascular toxicity (mean age, 42,4 (2,8) years, including men — n=3 (25%)), the control group — 22 patients without cardiovascular toxicity (mean age, 39,8 (1,7), including men — n=8 (36%)). Cardiovascular toxicity was verified on the basis of a combination of specific cardiological complaints with a decrease in the left ventricular ejection fraction >10% from the baseline or in absolute terms less than 53% and/or a decrease in the left ventricular longitudinal systolic strain >12% from the baseline and/or an increase in NT-proBNP >125 pg/ml.Results. The study presents the identified genetic features in oncohematological patients in the context of cardiovascular toxicity. ABCC5 rs1879257, PRKAG2 rs13224758, RYR2 rs10925391 and SLC22A7 rs414917 variants had a significant association with an increased risk of cardiovascular toxicity in the target group of patients by 5-6 times. In addition, the ABCB1 rs2032582 variant showed the opposite effect and was associated with a reduced risk of cardiovascular complications, having a protective effect on the cardiovascular system.Conclusion. Although further studies are needed to confirm the diagnostic and prognostic significance of the detected genetic variants, the study results indicate the prospects of genetic screening before antitumor immunochemotherapy as a future tool for stratifying oncohematological patients and minimizing cardiovascular toxicity.
Somatometric characteristics of patients with Wolff-Parkinson-White syndrome
Authors: Tolstokorova Yu. A. , Nikulina S. Yu. , Chernova A. A. 
Published: November 2024

Aim. To study the distribution of somatometric indicators and indices of patients with Wolff-Parkinson-White (WPW) syndrome.Material and methods. All patients underwent following clinical and paraclinical investigations: electrocardiography (ECG), Holter ECG monitoring, echocardiography. In addition, we performed somatometric study according to the standard method of V.V. Bunak. The main group consisted of 200 patients with WPW syndrome (men, n=97 (32,6±9,4 years); women, n=103 (47,92±11,6 years)).Results. Anthropometry performed according to James Tanner revealed that in the general group of WPW syndrome individuals, mesomorphs prevailed (57%). A similar pattern was observed both in the groups of women (25,5%) and men (31,5%). According to the Rees-Eysenck index, the general group of WPW syndrome individuals, normosthenics (37%) and pyknics (38%) prevailed. However, in the group of women, normosthenics prevailed (24%), and in the group of men, pyknics (23,5%). The relationship analysis using Pearson's chi-squared test revealed the following: in the group of women, the WPW syndrome was moderately correlated with the thigh fat fold (0,52), and in the group of men — with the abdominal fat fold (0,56).Conclusion. Somatometric study, taking into account the indices (J. Tanner, Rees-Eysenck), confirms the relationship between the risk of cardiovascular diseases and overweight. This can be useful for taking preventive measures in relation to groups of people with certain anthropometric features, when assessing the risk of arrhythmias within the concept of personalized medicine.