bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural and evolutionary analyses of the mitochondrial genome of Spuriopimpinella brachycarpa
Authors: Han Jun , Xu Wenbo , Yu Huanxi , Han Yun , Zhu Ming 
Published: November 2024

IntroductionSpuriopimpinella brachycarpa (Kom.) Kitag., a member of the Apiaceae family, is a perennial aromatic herb native to Northeast Asia with applications in culinary and traditional medicine. Despite its significance, most studies on S. brachycarpa have primarily focused on its phytochemical properties, with limited insights into its molecular and genomic characteristics.MethodsThis study presents the sequencing and assembly of the mitochondrial genome (mitogenome) of S. brachycarpa using second- and third-generation high-throughput sequencing technologies. Comprehensive analyses were performed on its structural organization, RNA editing sites, relative synonymous codon usage (RSCU), and repeat sequences. Comparative analyses with closely related species were also conducted.ResultsThe mitogenome exhibited a multi-branched structure, with a total length of 523,512 bp and a GC content of 43.37%. Annotation revealed 30 unique protein-coding genes, 21 tRNA genes, and three rRNA genes. Comparative analysis indicated that the S. brachycarpa mitogenome contains structural variations but shares collinear features with other Apiaceae species. We identified 618 potential RNA editing sites involving C-to-U conversions and discovered 59 homologous fragments between the mitogenome and plastome, comprising 8.13% of the mitogenome.DiscussionThese results enrich the genomic database of Apiaceae, providing valuable insights into the evolutionary relationships and genetic diversity within the family.
Allelopathy and underlying mechanism of mango (Mangifera indica) peel extracts on Alexandrium catenella
Authors: Wang Yanqun , Zang Yu , Zhao Wenxi , Xu Mengxue , Bai Jie , Li Li 
Published: November 2024

Harmful algal blooms (HABs) have always been a worldwide environmental issue. The methods based on the principle of allelopathy provide a novel direction for controlling HABs; however, there are a few studies on the application of allelopathic algaecides to control harmful algae in marine environments. Here we examined the algicidal capacity of 15 fruit peel extracts with biological activity on Alexandrium catenella. The results displayed that the mango peel extracts (MPE) showed efficient inhibition on species growth. The algicidal rate reached 93.32 ± 0.56% at 96 h after adding 5 g/L MPE to the culture medium of A. catenella. Furthermore, we found that the expression of key genes involved in PSII and PSI was downregulated as well as obstructed the electron transportation in the light reaction process and the synthesis of organic matter. The blocked photosynthetic chain induced the accumulation of substantial reactive oxygen species, resulting in severe peroxidation of the membrane lipids. Simultaneously, the expression pattern of key genes involved in the fatty acid, amino acid, and peroxisome breakdown pathways was upregulated, which suggested that the synthesis and decomposition of intracellular organic matter may be in an imbalanced state. The results above indicated that oxidative damage and energy metabolism disequilibrium are two key pathways by which MPE induced algal cell death. Furthermore, several kinds of active substances and their proportion in MPE had been identified by liquid chromatography quadrupole time-of-flight mass spectrometry. It is speculated that esters may be the important component playing an algicidal effect. However, the specific substance that plays a key role in inhibiting the growth of A. catenella and the algicidal mechanism remain to be further studied. This study might provide a new direction in the management of HABs in the future.
Suicide in older adults in Honduras: a retrospective analysis (2008-2022)
Authors: Irías Escher María José , López Castro Virna Julisa , Yup de León Pablo 
Published: November 2024

IntroductionThis study examines suicide among older adults in Honduras over a 15-year period (2008-2022).MethodsData were collected from the National Violence Observatory attached to the University Institute of Democracy, Peace and Security of the National Autonomous University of Honduras (ONV-IUDPAS-UNAH), and 593 suicide cases were analyzed with a quantitative approach of descriptive scope, to identify suicide decedent characteristics and patterns in the cases.ResultsIt was observed that 94.1% of the suicide decedents were male, with an average age of 70 years, predominantly from urban areas; the highest prevalence was in 2021 (7.77), generally in the mornings and mostly by hanging or asphyxiation in private spaces.DiscussionThere is a significant difference in the prevalence of suicide by gender (16 males per female). Similar to worldwide reports, an increase in post-pandemic suicides is observed. The aging of the population and the increasing incidence of suicide in older adults gives relevance to this study, which has been limited by the lack of systematic data collection and previous research that would allow a better understanding of the problem and, in turn, the generation of public policies focused on the mental health of older adults.
Exploring the regenerative capacity of the spleen following irradiation
Authors: Short Christie T. M. , O’Neill Helen C. , Tan Jonathan K. H. 
Published: November 2024

IntroductionHaematopoietic stem cell transplantation (HSCT) is commonly used to treat patients with haematological disorders. Myeloablative conditioning is an important preparation for patients receiving haematopoietic stem cells (HSC) or haematopoietic stem and progenitor cells (HSPC). While widely successful, HSCT is still associated with high rates of mortality. The recovery time between complete myeloablation and haematopoietic recovery is a large factor in the recovery rate. Successful engraftment of HSC is also directly correlated with the number of HSC niches available. This highlights the importance of the haematopoietic niche and its recovery from myeloablation as an important therapeutic target.MethodsThis murine model study specifically considers changes in spleen tissue architecture and cellular composition involving stromal and vascular cells that occur following lethal irradiation.ResultsSpleen recovered fully between 4- and 8-weeks after irradiation due to reconstitution by HSPC from bone marrow. Specific temporal changes in spleen architecture were identified, and these were linked to the cell types that constitute the white pulp, red pulp and marginal zones. Mesenchymal stromal cells returned before endothelial cells, and reticular cell types recovered more quickly in spleen following irradiation. Losses in gp38+ fibroblastic reticular cells and MAdCAM-1+ marginal reticular cells were associated with loss of the white pulp in the first 4 weeks following irradiation. White pulp was restored following recovery of supporting reticular cells.DiscussionThis study tests how spleen regeneration following a lethal dose of irradiation can be influenced by co-infusion of bone marrow HSPC together with either neonatal spleen stromal cells, or cells of the stromal STX3 line. Both the infusion of neonatal spleen stromal cells and STX3 stromal cells hastened recovery of both mesenchymal and vascular compartments. Following neonatal spleen stromal cell infusion, endothelial cells increased early, but a delay in structural reformation of distinct red and white pulp areas was found. Results from this study show that spleen regeneration can be influenced and even hastened through cellular therapy. Neonatal spleen stromal cells, co-infused together with HSPC following irradiation conditioning, represent a potential therapeutic opportunity for hastening spleen regeneration.
Revealing administrative staff roles in primary care during the COVID-19 pandemic: a qualitative study of family physicians’ perspectives
Authors: Marshall Emily Gard , Moritz Lauren R. , Buote Richard , Mathews Maria , Lukewich Julia , Brown Judith Belle , Sibbald Shannon , Munene Abraham , Hedden Lindsay , Ryan Dana , Spencer Sarah 
Published: November 2024

BackgroundAdministrative staff in primary care undertake numerous tasks to support patient care delivery. Although their roles are often overlooked, administrative staff are essential to the coordination and operations of primary care clinics. The COVID-19 pandemic introduced additional clinical and administrative tasks, including transitioning to virtual appointments and triaging patients for urgency, changing typical workflows. In Canada, existing pandemic plans for primary care did not account for these administrative tasks, nor the support that family physicians would require to continue to provide patient access to primary care. This research seeks to describe and understand the perceptions and experiences of family physicians of their administrative staff roles in primary care during the COVID-19 pandemic, to help inform future pandemic planning.MethodsWe present findings from a qualitative case study across four regions in Canada: Vancouver Coastal health region in British Columbia, Ontario Health West region, the province of Nova Scotia, and the Eastern Health region of Newfoundland and Labrador. We conducted semi-structured qualitative interviews with family physicians (n = 68) across the four regions and thematically analysed the data.ResultsWe identified five salient themes in the data, including (1) applying public health guidelines, (2) educating patients on COVID-19 and COVID-19 services, (3) re-organizing patient visits, (4) maintaining adequate staffing, and (5) recognizing administrative staff contributions. During the COVID-19 pandemic, family physicians took on numerous additional roles to reduce the risk of transmission of the virus with the support of their administrative staff. Family physicians emphasized the challenges of maintaining adequate staffing, and the importance of administrative staff in enabling the provision of primary care.ConclusionsExisting pandemic plans do not account for increased administrative roles taken on by primary care administrative staff. Pandemic plans must include guidance for the roles taken on by primary care administrative staff, such as clinical tasks, as they will continue to play an important role in pandemic recovery. Supporting administrative staff would enhance primary care providers’ ability to manage care during pandemics, facilitate resilience, and decrease provider and administrative burnout.
Operationalization of the social cognitive theory to explain and predict physical activity in Germany: a scale development
Authors: Egele Viktoria S. , Stark Robin 
Published: November 2024

IntroductionSocial cognitive theory is one of the most prominent psychological theories regarding human behavior. Previous research tested and confirmed parts of the theory concerning the explanatory and predictive value of the theory, both in specific populations and in selected domains of physical activity. However, the value of this research is limited as researchers often use their own item sets rather than validated scales. Therefore, comparability of the studies is restricted and the quality of the individual findings can often not be conclusively assessed as psychometric properties of the measurement are unclear. The goal of this research was to develop a parsimonious, reliable, and valid questionnaire to assess the elements of SCT in the context of physical activity.MethodsIn total, 90 items were developed for the four factors of SCT, which were then examined by exploratory factor analysis and reduced to 18 items in total.ResultsCross-validation was successful. Internal consistency was good for the four subscales, test-retest reliability was satisfactory, as were indicators for convergent and divergent validity.DiscussionA short, reliable, and valid instrument was developed intended for use in the general adult population in Germany for research on theoretical assumptions and interventions based on social cognitive theory.
The impact of agricultural product branding on farmers’ income inequality: evidence from China
Authors: Zheng Jialong , Li Guangsi 
Published: November 2024

IntroductionIncome inequality is related to farmers’ welfare, access and satisfaction. Addressing income inequality among farmers is particularly urgent as it is growing. So, as an important symbol of the development of the agricultural industry, what is the impact of agricultural product branding on farmers’ income inequality?MethodsTo answer this question, this paper uses panel data from 1986 counties in China from 2000 to 2021 and employs the Recentered Influence Function (RIF) method to explore the impact of agricultural product branding (APB) on farmers’ income inequality and its mechanism of action.Results and discussionThe results of the study show that while the APB boosted farmers’ incomes by an average of 1.6%, they exacerbated farmers’ income inequality by an average of 0.4% (using the Gini coefficient as an example). Mechanistic analysis shows that the APB exacerbates farmers’ income inequality by widening the gap between counties in terms of the level of adoption of agricultural technology and agricultural labor productivity. Heterogeneity analysis reveals that, compared to non-agricultural provinces, the APB in agricultural provinces reduces interregional farmers’ income inequality. Furthermore, the APB in the grain category mitigates this inequality, whereas the APB in the cash crop and aquatic product categories exacerbates it. The APB in the livestock category, however, has no significant effect on interregional farmers’ income inequality. Considering these findings, the government should regularly assess the impact of agricultural branding policies on income inequality among farmers and adjust policies in a timely manner to ensure their effectiveness and fairness.
Perforated Kirschner wire tension band in the treatment of Mayo IIA olecranon fractures
Authors: Yu Xiang , Li Qi , Li Yu-Zhi , Lu Hai-Jian , Ao Rong-Guang , Liu Bing-Li 
Published: November 2024

PurposeTo explore the clinical efficacy of perforated Kirschner wire tension band in the treatment of Mayo IIA olecranon fracture.MethodA retrospective study was conducted to analyze the clinical data of 96 adult patients with olecranon fractures of the ulna. Thirty-four cases underwent perforated Kirschner wire tension band fixation(group A), which included 21 males and 13 females, with an average age of 49.1 ± 11.57 years. Thirty-two cases received fixation with an olecranon anatomical plate (group B), comprising 19 males and 13 females, with an average age of 48.9 ± 8.84 years. Additionally, 30 cases were treated with ordinary Kirschner wire tension band fixation (group C), consisting of 18 males and 12 females, with an average age of 46.6 ± 12.03 years. The study compared various outcomes among the three groups, including operation time, intraoperative blood loss, number of fluoroscopy exposures, postoperative visual analogue score (VAS), fracture healing time, internal fixation failure rates, skin irritation rates, and the Broberg-Morrey score for elbow joint function at the final follow-up.ResultAll patients were followed for a duration of 15 to 21 months, with an average follow-up period of 18 months. The operation time, intraoperative blood loss, number of fluoroscopy sessions, fracture healing time, and incidence of skin irritation for group A were recorded as (73.8 ± 11.72) min, (113.5 ± 20.73) milliliters, (7.5 ± 1.96) times, and (3.7 ± 1.46) months, respectively, with 1 case of skin irritation. In group B, the corresponding values were (98.4 ± 10.46) min, (154.7 ± 20.11) milliliters, (11.8 ± 2.78) times, and (4.3 ± 1.69) months, with 5 cases of skin irritation. For group C, the values were (81.7 ± 15.66) min, (115.5 ± 18.82) milliliters, (7.3 ± 1.99) times, and (4.3 ± 1.86) months, with 7 cases of skin irritation. Group A demonstrated superior outcomes compared to group B in terms of intraoperative blood loss and number of fluoroscopy sessions, and outperformed both group B and group C regarding operation time, fracture healing time, and skin irritation. These differences were statistically significant (P &lt; 0.05).ConclusionPerforated Kirschner wire Tension band is an effective method for treating olecranon fractures. This technique is associated with a short operative time, minimal intraoperative blood loss, and a reduced need for fluoroscopy. Additionally, it promotes fracture healing and significantly reduces the risk of complications, such as postoperative skin irritation.
Tecnologias Assistivas para adultos com doenças neurológicas: revisão sistemática
Authors: Pereira Gabriela de Jesus Souza , Ferreira Letícia Simões , Favero Francis Meire 
Published: November 2024

Introdução. A tecnologia assistiva é um termo que indica todos os produtos, instrumentos, estratégias, serviços e práticas que auxiliam nas funções do cotidiano dos indivíduos com alguma deficiência ou incapacidade sendo dividida em categorias. Objetivos. Identificar as principais tecnologias assistivas existentes para pacientes neurológicos adultos apontadas na literatura científica. Método. Trata-se de um estudo de revisão sistemática, realizado nas bases de dados SciELO, PubMed/Medline e Lilacs, sendo incluídos artigos entre 2018 e 2020. A fim de melhorar o relato dos artigos encontrados, foi seguida a recomendação PRISMA. Resultados. A análise de 12 artigos revelou que "Auxílios de Mobilidade" foi a categoria mais frequente, com cadeiras de rodas sendo a tecnologia mais utilizada, seguida por "Órteses e Próteses", principalmente órteses. Conclusão. Adultos com doenças neurológicas demonstram alta demanda por "Auxílios de Mobilidade" e "Órteses e Próteses", refletindo suas dificuldades em locomoção, transferência e postura. Esses achados destacam a necessidade de maior acesso e investimento em TA para essa população.
Avaliação de saúde bucal em pacientes com psoríase – revisão de literatura
Authors: Correia Evelyn Kaline Nascimento , Garcia Karolina da Silva , Frota Mayara Tabal da , Silva Alenildo Pereira da 
Published: November 2024

A psoríase acomete de 1 a 3 % da população é uma doença de pele, sistêmica, inflamatória e crônica, não contagiosa, hiper proliferativa de etiologia desconhecida, apresenta diversas variações clínicas e graus de severidade não apresenta predileção de gênero. A psoríase é classificada como uma doença autoimune e a predisposição genética. O objetivo deste trabalho, éa saúde bucal e da existência de lesões orais em paciente com psoríase. Metodologia: Foi realizado uma pesquisa nas principais bases de dados (Medline, PubMed, Scielo e Cochrane) utilizando-se os descritores: “psoriase”, “doença periodontal”, “lesão da cavidade oral”. Foram selecionados artigos, dissertações e tese, Também foram consultados alguns livros textos sobre o assunto. Como resultados obtidos, verificou-se que a psoríase pode prejudicar a saúde bucal, causando problemas como perda óssea e bolsas periodontais, além de inflamações e fatores como tabagismo e falta de higiene bucal, que pioram o quadro. Conclui-se que as implicações clinicas para o tratamento de pacientes com psoríase e sugestões para futuras pesquisas. Os estudos das repercussões orais da psoríase, é um campo a ser mais explorado, pois muitas questões permanecem em aberto.
Analyzing the financial performance by using financial ration a case study on al salam bank Algeria during the period 2013 – 2022
Authors: Fatiha Bouhrine , Salima Tebaibia , Bilel Mrabet 
Published: November 2024

This study aims to analyze the performance of Al Salam Bank of Algeria using financial indicators. In order to achieve the goal of the study, the descriptive analytical approach was used by describing and analyzing the theoretical aspect 3knowing the relationship between financial indicators and performance expressed as ROA & ROE, and all of this using the Data Tab program, The study reached several results, the most important of which is: The study finds a significant strong, positive significance impact of financial ration variables on the performance of salam bank under study during the period specified.
Estudio de Bienestar del estado Bolívar
Authors: Mantilla Aiskel Andrade , Maldonado Jesús Medina , Castro Otaiza Cupare , Carrillo Marian Ojeda 
Published: November 2024

El bienestar, concepto polisémico y multifactorial, fue concebido como una especie de orden social en el cual las personas alcanzan logros que favorecen el desarrollo individual como social (Di Pasquale, 2015). La medición fue abordada desde la combinación de componentes objetivos, que refieren la capacidad de una persona de satisfacer sus necesidades mediante el acceso a recursos y oportunidades para vivir dignamente; y componentes subjetivos que expresan la valoración o satisfacción que tiene acerca de su vida. Las dimensiones estudiadas fueron salud, educación, ingreso y consumo, empleo, vivienda, acceso a servicios públicos, seguridad, relaciones sociales y participación comunitaria. El estudio fue de tipo descriptivo, con enfoque cuantitativo y diseño de campo. La población proyectada del estado Bolívar, para el año 2023 fue de 1.654.518 habitantes, calculada mediante un análisis de regresión, con los resultados de los censos realizados desde 1950 hasta 2011. La muestra, estratificada por edad y sexo con nivel de confianza de 96%, la conformaron 656 personas, distribuidas proporcionalmente en los once municipios del estado. El cuestionario fue el instrumento de recolección de información, que abordaron las nueve dimensiones del bienestar y los dos componentes descritos anteriormente. El estudio permitió caracterizar las condiciones básicas de vida de los habitantes del estado para cada dimensión del estudio y la valoración, en términos de satisfacción, que hacen de esas condiciones. Se obtuvo como resultado un promedio de los componentes objetivos y subjetivos por cada dimensión trabajada y, con estos, se calculó el promedio de bienestar del estado.
Mapeamento e análise da cadeia produtiva do coco verde (Cocos nucifera L.) no Sul da Bahia: limites e oportunidades
Authors: Cajaes Edirlan Rosa , Rezende Enio Antunes 
Published: November 2024

Diante da importância do agronegócio no Brasil e a produção do coco verde cada vez mais crescente e significativa, o propósito do presente estudo foi analisar e mapear a cadeia produtiva agroindustrial do coco verde na região Sul da Bahia. Metodologicamente, iniciou-se por um levantamento bibliográfico contemplando uma abordagem qualitativa de caráter exploratório, sustentada por uma estrutura teórica baseada nos conceitos sobre Commodity System Approach (CSA) e Analyse de Filière (CPA), em consonância com uma pesquisa de campo a fim de vislumbrar na prática a dinâmica da cadeia produtiva do coco, identificando os atores envolvidos. Para a identificação dos membros da cadeia, usou-se o método snowball, enquanto que para o levantamento dos dados aplicou-se questionários por meio de entrevistas aos representantes de cada segmento. A análise dos resultados permitiu caracterizar a cadeia produtiva do coco, bem como as percepções dos agentes quanto as dificuldades e oportunidades encontradas na região, o que constatou o potencial da fibra da casca do coco. Tais implicações sugerem que esse setor não se encontra consolidado por falta de investimentos do Estado e uma estruturação deficiente na cadeia produtiva estudada.