bluuebunny/crossref_metadata_2025_split huggingface dataset:
Forschung zu Leistungen zur Teilhabe am Arbeitsleben: Zum Wissenstransfer zwischen Theorie und Praxis
Authors: Bartel Susanne , Ohlbrecht Heike 
Published: June 2018

Zusammenfassung
Ziel der Studie Diese Untersuchung richtet sich auf den Theorie-Praxis-Transfer auf dem Gebiet der Forschung zur Teilhabe am Arbeitsleben (LTA). Ziel war es zu ermitteln, welche Erwartungen auf Seiten der Leistungserbringer hinsichtlich der Forschung vorherrschen, welchen Zugang sie zu wissenschaftlichen Erkenntnissen suchen, wie sich der Praxistransfer vollzieht und welche Forschungsdesiderate vorliegen. Flankierend wurden Vertreter der Rentenversicherung aus dem Bereich der Forschungsförderung nach den internen Strukturen zur Identifizierung von Forschungsthemen und der Bewertung von Forschungsergebnissen sowie zum Wissenstransfer befragt. Ziel des Beitrages ist es, das Verhältnis von Forschung und Praxis im Bereich LTA zu problematisieren und eine Sensibilität für dieses Thema zu schaffen.
Methodik Die Ergebnisse dieser Studie gründen auf einer schriftlichen Befragung von 28 Berufsförderungswerken (BFW) des Bundesverbandes Deutscher Berufsförderungswerke e. V. (BV BFW) und auf 3 Experteninterviews mit Vertretern der Rentenversicherung (Bund und Regional). Die Rücklaufquote der BFW-Befragung lag bei rd. 54% (N=15). Die Auswertung erfolgte primär qualitativ-inhaltsanalytisch sowie mit einer damit einhergehenden schrittweisen Kodierung des Materials.
Ergebnisse Die Ergebnisse der Befragung verweisen auf einen ausgeprägten Bedarf nach Translationsprozessen und einer Kooperationskultur zwischen Forschung und Praxis. Gleichzeitig wurde ein Spannungsverhältnis zwischen dem Wahren der Autonomie von Forschung und einer zunehmenden Transferorientierung deutlich. Darüber hinaus konnten vielfältige Ansätze zur Ausgestaltung von möglichen Transferaktivitäten herausgearbeitet werden.
Schlussfolgerung Im Bereich der Forschungen zur LTA stellt die Entwicklung eines Strategiekonzeptes für den Forschungstransfer eine zukünftige Entwicklungsaufgabe dar. Dabei ist es erforderlich, neue Kommunikationsstrukturen und partizipative Forschungsformate zu entwickeln, in denen Forschergruppen und -förderer sowie Praxisakteure gemeinsam LTA-Forschung realisieren können.
Qualität und Zufriedenheit mit der chirurgischen Famulatur aus studentischer Sicht
Authors: Froehlich Susanne , Goebel Florian , Meder Adrian , Wirkner Janine , Obertacke Udo , Kasch Richard 
Published: June 2018

Zusammenfassung
Einleitung Der chirurgischen Famulatur kommt eine besondere Bedeutung zu, da dem Studierenden erstmals ein längerer Kontakt zu den ärztlichen Kollegen und zu den Patienten ermöglicht wird und Fachrichtungsneigungen vertieft werden können. Wie Medizinstudierende ihre Famulatur in der Fachrichtung Chirurgie wahrgenommen haben, soll durch die vorliegende Arbeit geklärt werden.
Methoden Eine 2012 durchgeführte bundesweite Onlinebefragung mit 9079 Teilnehmern enthielt eine Evaluation der abgeleisteten curricularen Praktika. In die vorliegende Auswertung flossen die Daten der Befragten ein, die eine mindestens 4-wöchige Famulatur in der Chirurgie absolviert hatten (n = 526). Besonderes Interesse galt folgenden Fragestellungen: Gesamtbewertung, Zufriedenheit, Struktur und Qualität der Lehre, Bewertung der Lehrenden und Erwerb von praktischen Kompetenzen, die anhand von 35 Items erfragt wurden. Neben der deskriptiven Statistik wurden für Häufigkeiten der Chi-Quadrat-Test sowie für die einzelnen Items univariate ANOVAs mit dem Zwischensubjektfaktor „Gruppe“ (ermittelt anhand der Gesamtbeurteilung: „zufrieden“, „neutral“, „unzufrieden“ mit der Famulatur) durchgeführt.
Ergebnisse Der weibliche Anteil der Studierenden betrug 56,7%, das Durchschnittsalter lag zum Zeitpunkt der Befragung bei 25 Jahren. In allen ausgewerteten Items fanden sich signifikante Unterschiede zwischen zufriedenen und unzufriedenen Studierenden. Die Teilnehmer der Befragung, die mit der Gesamtfamulatur zufrieden waren, bewerteten die fachliche und didaktische Qualität der Lehre und den Erwerb von praktischen Kompetenzen signifikant besser als unzufriedene Studierende (alle p < 0,000).
Diskussion Wenig ist über die Effekte studiumsbegleitender Praktika, zu denen die Famulatur gehört, publiziert. Diese Informationen scheinen jedoch insofern wichtig, da die Fachrichtung, in der die Famulatur absolviert werden kann, entsprechend den Neigungen frei wählbar ist. So kann bereits in dieser frühen Ausbildungsphase durch Optimierung vorhandener Strukturen und Verbesserung des Lehrangebotes zumindest versucht werden, Nachwuchs für den Fachbereich Chirurgie zu rekrutieren oder nicht definitiv zu verlieren.
Bilateral Radial Agenesis in a Cat Treated with Bilateral Ulnocarpal Arthrodesis
Authors: Bezhentseva Alla , Singh Harpreet , Boudrieau Randy 
Published: June 2018

Objective This article describes corrective antebrachiocarpal re-alignment and arthrodesis for bilateral radial hemimelia (radial agenesis) in an 8-month-old domestic short-haired cat.
Methods Bilateral forelimb deformity of ulnocarpal varus with complete luxation and rotation of the antebrachiocarpal joint spaces, and joint contracture, was observed. Several carpal bones and metacarpal bones I and II and their associated phalanges were absent. Abnormal ambulation and weight bearing on the dorsolateral part of the manus were present. The deformities were treated by bilateral distal ulnar ostectomy and ulnocarpal arthrodesis using a 2.0-mm locking compression plate applied with hybrid fixation and allograft.
Results Successful deformity correction was obtained with subsequent fusion of the antebrachiocarpal joints. No complications were observed. At long-term follow-up (4.75 years), there was good-to-excellent functional result, with approximately 15° internal rotation of the right forelimb manus and shortened stride with slight circumduction and lameness. All implants remained stable and continued bone remodelling was present. The cat was assessed to have good-to-excellent short- and long-term functional results with excellent owner satisfaction.
Clinical Significance Treatment of radial agenesis in the cat has previously been limited to conservative management or limb amputation. While there are several reports of corrective limb-sparing procedures used to treat dogs, this is the first report of a cat with successful salvage corrective surgery.
Coronary Artery Bypass Grafting in Diabetic Patients: Complete Arterial versus Internal Thoracic Artery and Sequential Vein Grafts—A Propensity-Score Matched Analysis
Authors: Kunihara Takashi , Wendler Olaf , Heinrich Kerstin , Nomura Ryota , Schäfers Hans-Joachim 
Published: June 2018

Abstract
Background The optimal choice of conduit and configuration for coronary artery bypass grafting (CABG) in diabetic patients remains somewhat controversial, even though arterial grafts have been proposed as superior. We attempted to clarify the role of complete arterial revascularization using the left internal thoracic artery (LITA) and the radial artery (RA) alone in “T-Graft” configuration on long-term outcome.
Methods and Results From 1994 to 2001, 104 diabetic patients with triple vessel disease underwent CABG using LITA/RA “T-Grafts” (Group-A). Using propensity-score matching, 104 patients with comparable preoperative characteristics who underwent CABG using LITA and one sequential vein graft were identified (Group-V). Freedom from all causes of death, cardiac death, major adverse cardiac event (MACE), major adverse cardiac (and cerebral) event (MACCE), and repeat revascularization at 10 years of Group-A was 60 ± 5%, 67 ± 5%, 48 ± 5%, 37 ± 5%, and 81 ± 4%, respectively, compared with 58 ± 5%, 70 ± 5%, 49 ± 5%, 39 ± 5%, and 93 ± 3% in Group-V. There were no significant differences in these end points between groups regardless of insulin-dependency. Multivariable Cox proportional hazards model identified age, left ventricular ejection fraction, renal failure, and hyperlipidemia as independent predictors for all death, age and left ventricular ejection fraction for cardiac death, sinus rhythm for both MACE and MACCE, and prior percutaneous coronary intervention for re-revascularization.
Conclusions In our experience, complete arterial revascularization using LITA/RA “T-Grafts” does not provide superior long-term clinical benefits for diabetic patients compared with a combination of LITA and sequential vein graft.
Wearable Cardioverter–Defibrillators following Cardiac Surgery—A Single-Center Experience
Authors: Heimeshoff Jan , Merz Constanze , Ricklefs Marcel , Kirchhoff Felix , Haverich Axel , Bara Christoph , Kühn Christian 
Published: June 2018

Background A wearable cardioverter–defibrillator (WCD) can terminate ventricular fibrillation and ventricular tachycardias via electrical shock and thus give transient protection from sudden cardiac death. We investigated its role after cardiac surgery.
Methods We retrospectively analyzed all patients who were discharged with a WCD from cardiac surgery department. The WCD was prescribed for patients with a left ventricular ejection fraction (LVEF) of ≤35% or an explanted implantable cardioverter–defibrillator (ICD).
Results A total of 100 patients were included in this study, the majority (n = 59) had received coronary artery bypass graft surgery. The median wearing time of a WCD patient was 23.5 hours per day. LVEF was 28.9 ± 8% after surgery and improved in the follow-up to 36.7 ± 11% (p < 0.001). Three patients were successfully defibrillated. Ten patients experienced ventricular tachycardias. No inappropriate shocks were given. An ICD was implanted in 25 patients after the WCD wearing period.
Conclusion Ventricular arrhythmias occurred in 13% of the investigated patients. LVEF improved significantly after 3 months, and thus a permanent ICD implantation was avoided in several cases. Sternotomy did not impair wearing time of the WCD. A WCD can effectively protect patients against ventricular tachyarrhythmias after cardiac surgery.
Cervical Cancer Registered in Two Developed Regions from Brazil: Upper Limit of Reachable Results from Opportunistic Screening
Authors: Teixeira Julio Cesar , Maestri Carlos Afonso , Machado Helymar da Costa , Zeferino Luiz Carlos , Carvalho Newton Sérgio de 
Published: June 2018

Objective The aim of this study was to assess the time trends and pattern of cervical cancer diagnosed in the period from 2001 to 2012 by means of an opportunistic screening program from two developed regions in Brazil.
Methods An observational study analyzing 3,364 cancer records (n = 1,646 from Campinas and n = 1,718 from Curitiba region) available in hospital-based cancer registries was done. An additional 1,836 records of CIN3/AIS from the region of Campinas was analyzed. The statistical analysis assessed the pooled data and the data by region considering the year of diagnosis, age-group, cancer stage, and histologic type. The Cochran-Armitage trend test was applied and p-values < 0.05 were considered significant.
Results The total annual cervical cancer registered from 2001 to 2012 showed a slight drop (273–244), with an age average of 49.5 y, 13 years over the average for CIN3/AIS (36.8 y). A total of 20.6% of the diagnoses (1.6% under 25 y) were done out of the official screening age-range. The biennial rate of diagnoses by age group for the region of Campinas showed an increase trend for the age groups under 25 y (p = 0.007) and 25 to 44 y (p = 0.003). Stage III was the most recorded for both regions, with an annual average of 43%, without any trend modification. There was an increasing trend for stage I diagnoses in the region of Campinas (p = 0.033). The proportion of glandular histologic types registered had an increased trend over time (p = 0.002), higher for the region of Campinas (21.1% versus 12.5% for the region of Curitiba).
Conclusion The number, pattern and trends of cervical cancer cases registered had mild and slow modifications and reflect the limited effectivity of the opportunistic screening program, even in developed places.
Safety of Drug-Eluting-Beads Transarterial Chemoembolization for Unresectable Hepatocellular Carcinoma in Patients with Transjugular Intrahepatic Portosystemic Shunt
Authors: Rief Katherine , Pirasteh Ali , Shenoy-Bhangl Anuradha , Ganguli Suvranu , Kalva Sanjeeva 
Published: June 2018

Abstract
Purpose To assess the safety of drug-eluting beads transarterial chemoembolization (DEB-TACE) for unresectable hepatocellular carcinoma (HCC) in patients with transjugular intrahepatic portosystemic shunt (TIPS).
Materials and Methods Records of patients with a patent TIPS who underwent DEB-TACE for inoperable HCC from 2005 to 2014 at two institutions were reviewed. Patient demographics, number of procedures, extent of embolization (lobar vs. segmental), 30-day mortality, and postprocedure adverse events classified based on Common Terminology Criteria for Adverse Events (CTCAE V4.03) were recorded.
Results From the total of 10 patients included (6 male, average age: 59), 3 were classified as Child A and 7 as B. Tumor Barcelona clinic liver cancer (BCLC) stage was A in three patients, B in six, and C in one. Patients underwent doxorubicin DEB-TACE with a median dose of 100 mg (range: 50–100). Number of TACE procedures per patient ranged from 1 to 4 (median: 1). Three (30%) patients experienced toxicity grade 2 or higher immediately following the procedure. One patient had grade 3 toxicity of aspartate transaminase (AST), alanine transaminase (ALT), and bilirubin. Three patients had extended hospital stays beyond 48 hours due to adverse events, including edema, acute pancreatitis, and a hepatic abscess discovered a week after the procedure. All 10 patients were alive and discharged from the hospital at 30 days after the procedure.
Conclusion DEB-TACE can be well tolerated by patients with a patent TIPS, given adequate liver function. Lobar DEB-TACE is associated with higher risk of complications.
“Push–Pull Technique” for the Management of a Selected Superomedial Intraorbital Lesion
Authors: Castelnuovo Paolo , Fiacchini Giacomo , Fiorini Francesca , Dallan Iacopo 
Published: June 2018

Orbital lesions are traditionally managed through external approaches when laterally located, and through a transnasal approach or other external approaches when medially located. However, when the lesion is superomedially located, it may determine a technical challenge.In this study, we present the case of a patient with a superomedial intraconal venous malformation of the left eye. We addressed the mass through a combined approach, using the transnasal route as the main approach, and the superior eyelid approach to push down the lesion to facilitate the excision. We have called this approach “push–pull technique.”We achieved a complete resection of the lesion and did not observe any intraoperative or postoperative complications. The last follow-up at 6 months postoperatively showed no recurrence, and the patient was satisfied and completely recovered.According to our experience, the “push–pull” technique seems to be a safe procedure and might be considered a valid alternative to address selected superomedial intraconal lesions.
Verlaufskarrieren und biografische Konstellationen beruflicher Rehabilitanden und deren Einflüsse auf Rückkehr und nachhaltigen Verbleib in Arbeit
Authors: Klaus Sebastian , Meschnig Alexander , von Kardorff Ernst 
Published: June 2018

Zusammenfassung
Ziele der Studie Mit dem Blick auf biografische (Risiko-)Konstellationen für Ge- und Misslingensbedingungen – und damit auf die Wirksamkeit und Nachhaltigkeit von Leistungen zur Teilhabe am Arbeitsleben – begleitet die Studie mit qualitativ-hermeneutischen Verfahren berufliche Rehabilitandinnen und Rehabilitanden über einen Zeitraum von etwa 2 Jahren nach der Umschulung auf dem Weg zurück ins Beschäftigungssystem.
Methode Die Studie folgt einem Mixed-Method-Design. Neben einer Fragebogenerhebung von insgesamt 214 Teilnehmern und 19 Interviews mit Experten aus Wissenschaft und Praxis bilden 30 episodisch-narrative Interviews mit teilnehmenden Rehabilitanden den Schwerpunkt des Forschungsdesigns.
Ergebnisse Insgesamt gelingt etwa 80% der Maßnahmenteilnehmer unseres Samples nach 18 Monaten der Übergang in Erwerbsarbeit. Entscheidende Hemmnisse für das Gelingen zeigen sich in charakteristischen Risikokonstellationen, die durch Umschulungsberufswahl, Umgang mit der Krankheit, Schonraumbedarf, Lebenslauforientierung, Zielorientierung, Akzeptanz einer Übergangsphase mit geringerer Entlohnung, regionaler berufsspezifischer Arbeitsmarkt sowie soziale Einbindung und Unterstützung gekennzeichnet sind.
Schlussfolgerungen Mithilfe qualitativ-hermeneutischer Verfahren wird es möglich über Diagnose(-zuschreibung) und andere aus der Theorie bekannte Aspekte hinausgehend, neue, für die Rehabilitanden wichtige Wirkfaktoren zum Return to Work zu generieren. Diese verweisen auf deren Einbettung in Prozesse, Kontexte, Zusammenhänge und Wechselwirkungen zwischen Biografie und Kontextfaktoren. Aus den Ergebnissen lassen sich konkrete Unterstützungsbedarfe und Handlungsansätze für kritische Risikokonstellationen entwickeln.
Analysing the role of virtualisation and visualisation on interdisciplinary knowledge exchange in stem cell research processes
Authors: Stephens Neil , Khan Imtiaz , Errington Rachel 
Published: June 2018

AbstractInterdisciplinary work is an increasingly frequent and important aspect of scientific research. However, successful knowledge exchange and collaboration between experts is itself a challenging activity with both technical and social components that require consideration. Here, this article analyses the cultural factors involved in interdisciplinary research, specifically in the context of a software programme designed to improve knowledge exchange. The authors undertook an ethnographic study to understand the impact of virtualisation and visualisation on an interdisciplinary research team, working together to develop novel imaging technologies for investigating stem cells. In this discovery-research environment the challenge was to determine the socio-technical effect of an in-house software tool called ProtocolNavigator, which provided a virtual laboratory environment for the team to simulate and map their ‘real-life laboratory’ activities. This display, together with activity icons and a timeline, could be visually analysed and transferred between multi-institutional researchers in a non-narrative approach. The aim of the work reported here is to provide the first detailed analysis of how software of this type is used in practice, and to analyse this through a robust social science-based perspective. Subsequently this study examines the effectiveness of this virtual laboratory environment on enhancing communication and understanding using a theoretical framework drawing upon three insights from the Sociology of Expertise and Experience: (i) interactional and contributory expertise, (ii) knowledge exchange and interpretative flexibility, and (iii) trading zones. The framework was extended by introducing the notion of material, concept and practice trade at these trading zones with a demonstration of how interactive visualisation of interconnected trading routes can empower interdisciplinary work. The addition of Foucault’s classic account of power found evidence of a panoptical effect due to the augmented visibility of each other’s work. In summary, the article offers a theoretical framework together with novel analysis to determine the influence of introducing tools and approaches designed to enhance interdisciplinary working—particularly in the context of knowledge sharing and trust.
The making of responsive innovation policies: varieties of evidence and their contestation in the Basque Country
Authors: Kleibrink Alexander , Magro Edurne 
Published: June 2018

AbstractIn the European Union (EU) multiple levels of governance interact in the design of public policies. Multi-level policies require a variety of evidence to define problems appropriately, set the right objectives and create suitable instruments to achieve them. How such a variety of evidence is used in practice, however, remains largely elusive. In 2013, the reformed EU Cohesion Policy brought about a sea change in the way governments must justify their investment priorities to support innovation and economic development. One of many new 'ex-ante conditionalities' sought to improve the design of regional innovation policies by putting strong emphasis on the underlying evidence base of policy strategies. A multitude of data sources had to be combined to meet this novel requirement in 120 regional and national strategy documents. Combining various data sources meaningfully was a necessary first step to engage with stakeholders from relevant business and research communities to jointly develop and decide on priorities for public investments. Stakeholder organisations had the opportunity to contest insights coming from official statistics. But how do governments reconcile insights from socio-economic analyses with differing views from stakeholders? We illustrate how such contestation of evidence has unfolded in the Basque Country. In this region, socio-economic analysis and broader stakeholder consultation rapidly confirmed three investment priorities that had been already quite established. Stakeholders from local governments, universities and other government departments contested this choice as not fully representative of the local potential and societal needs. Through their participation in a multi-stakeholder body advising the government they succeeded in adding four priorities that address local societal issues: sustainable food, urban living, culture and environmental protection. Our findings underline that rational planning using statistics gets governments only so far in meeting pressing societal challenges. Stakeholders contesting and complementing statistical insights make policies more responsive to local needs.
Two Short Essays by Árni Magnússon on the Origins of the Icelandic Language
Authors: Verri Giovanni , Tarsi Matteo 
Published: June 2018

Summary
This article presents two essays by the renowned Icelandic manuscript collector Árni Magnússon (1663‒1730): De gothicæ lingvæ nomine [On the expression ‘the Gothic language’] and Annotationes aliqvot de lingvis et migrationibus gentium septentrionalium [Some notes on the languages and migrations of the northern peoples]. The two essays are here edited and published in their original language, Latin. Moreover, an English translation is also presented for ease of access. After a short introduction (§ 1), a historical overview of the academic strife between Denmark and Sweden is given (§ 2). Subsequently (§ 3), Árni Magnússon’s life and work are presented. In the following Section (§ 4), the manuscript containing the two essays, AM 436 4to, is described. The two essays are then edited and translated in Section 5. In the last Section (§ 6), the two works are commented and Árni Magnússon’s scholarly thought evaluated.
SOPanG: online text searching over a pan-genome
Authors: Cisłak Aleksander , Grabowski Szymon , Holub Jan 
Published: June 2018

Abstract

Motivation
The many thousands of high-quality genomes available now-a-days imply a shift from single genome to pan-genomic analyses. A basic algorithmic building brick for such a scenario is online search over a collection of similar texts, a problem with surprisingly few solutions presented so far.

Results
We present SOPanG, a simple tool for exact pattern matching over an elastic-degenerate string, a recently proposed simplified model for the pan-genome. Thanks to bit-parallelism, it achieves pattern matching speeds above 400 MB/s, more than an order of magnitude higher than of other software.

Availability and implementation
SOPanG is available for free from: https://github.com/MrAlexSee/sopang.

Supplementary information
Supplementary data are available at Bioinformatics online.