bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Good Practice–Compliant Clinical Trial Imaging Management System for Multicenter Clinical Trials: Development and Validation Study
Authors: Shin Youngbin , Kim Kyung Won , Lee Amy Junghyun , Sung Yu Sub , Ahn Suah , Koo Ja Hwan , Choi Chang Gyu , Ko Yousun , Kim Ho Sung , Park Seong Ho 
Published: July 2019

Background
With the rapid increase in utilization of imaging endpoints in multicenter clinical trials, the amount of data and workflow complexity have also increased. A Clinical Trial Imaging Management System (CTIMS) is required to comprehensively support imaging processes in clinical trials. The US Food and Drug Administration (FDA) issued a guidance protocol in 2018 for appropriate use of medical imaging in accordance with many regulations including the Good Clinical Practice (GCP) guidelines. Existing research on CTIMS, however, has mainly focused on functions and structures of systems rather than regulation and compliance.

Objective
We aimed to develop a comprehensive CTIMS to meet the current regulatory guidelines and various required functions. We also aimed to perform computerized system validation focusing on the regulatory compliance of our CTIMS.

Methods
Key regulatory requirements of CTIMS were extracted thorough review of many related regulations and guidelines including International Conference on Harmonization-GCP E6, FDA 21 Code of Federal Regulations parts 11 and 820, Good Automated Manufacturing Practice, and Clinical Data Interchange Standards Consortium. The system architecture was designed in accordance with these regulations by a multidisciplinary team including radiologists, engineers, clinical trial specialists, and regulatory medicine professionals. Computerized system validation of the developed CTIMS was performed internally and externally.

Results
Our CTIMS (AiCRO) was developed based on a two-layer design composed of the server system and the client system, which is efficient at meeting the regulatory and functional requirements. The server system manages system security, data archive, backup, and audit trail. The client system provides various functions including deidentification, image transfer, image viewer, image quality control, and electronic record. Computerized system validation was performed internally using a V-model and externally by a global quality assurance company to demonstrate that AiCRO meets all regulatory and functional requirements.

Conclusions
We developed a Good Practice–compliant CTIMS—AiCRO system—to manage large amounts of image data and complexity of imaging management processes in clinical trials. Our CTIMS adopts and adheres to all regulatory and functional requirements and has been thoroughly validated.
Impact of an Intensive Care Information System on the Length of Stay of Surgical Intensive Care Unit Patients: Observational Study
Authors: Havel Camille , Selim Jean , Besnier Emmanuel , Gouin Philippe , Veber Benoit , Clavier Thomas 
Published: July 2019

Background
The implementation of computerized monitoring and prescription systems in intensive care has proven to be reliable in reducing the rate of medical error and increasing patient care time. They also showed a benefit in reducing the length of stay in the intensive care unit (ICU). However, this benefit has been poorly studied, with conflicting results.

Objective
This study aimed to show the impact of computerization on the length of stay in ICUs.

Methods
This was a before-after retrospective observational study. All patients admitted in the surgical ICU at the Rouen University Hospital were included, from June 1, 2015, to June 1, 2016, for the before period and from August 1, 2016, to August 1, 2017, for the after period. The data were extracted from the hospitalization report and included the following: epidemiological data (age, sex, weight, height, and body mass index), reason for ICU admission, severity score at admission, length of stay and mortality in ICU, mortality in hospital, use of life support during the stay, and ICU readmission during the same hospital stay. The consumption of antibiotics, biological analyses, and the number of chest x-rays during the stay were also analyzed.

Results
A total of 1600 patients were included: 839 in the before period and 761 in the after period. Only the severity score Simplified Acute Physiology Score II was significantly higher in the postcomputerization period (38 [SD 20] vs 40 [SD 21]; P<.05). There was no significant difference in terms of length of stay in ICU, mortality, or readmission during the stay. There was a significant increase in the volume of prescribed biological analyses (5416 [5192-5956] biological exams prescribed in the period before Intellispace Critical Care and Anesthesia [ICCA] vs 6374 [6013-6986] biological exams prescribed in the period after ICCA; P=.002), with an increase in the total cost of biological analyses, to the detriment of hematological and biochemical blood tests. There was also a trend toward reduction in the average number of chest x-rays, but this was not significant (0.55 [SD 0.39] chest x-rays per day per patient before computerization vs 0.51 [SD 0.37] chest x-rays per day per patient after computerization; P=.05). On the other hand, there was a decrease in antibiotic prescribing in terms of cost per patient after the implementation of computerization (€149.50 [$164 USD] per patient before computerization vs €105.40 [$155 USD] per patient after computerization).

Conclusions
Implementation of an intensive care information system at the Rouen University Hospital in June 2016 did not have an impact on reducing the length of stay.
Distribusi Dan Aktivitas Menggigit Nyamuk Genus Mansonia Yang Berpotensi Sebagai Vektor Filariasis di Wilayah Endemis Filariasis Desa Ligan dan Lhok Bout Aceh Jaya
Authors: Yulidar Yulidar , M.Diah Yasir , Wilya Veny , Zulhaida Andi 
Published: July 2019

Filariasis masih menjadi masalah pada masyarakat di desa Ligan dan desa Lhok Bout Kabupaten Aceh Jaya. Mansonia spp merupakan salah satu vektor filariasis di Indonesia. Penelitian ini bersifat cross sectional yang dilaksanakan pada bulan Pebruari-Desember 2017 di desa Ligandan Lhok Bout. Penangkapan nyamuk menggunakan metode umpan orang dalam dan luar rumah. Umpan orang duduk dalam kelambu. Hasil penelitian didapatkan total jumlah nyamuk Mansonia spp tertangkap adalah 58 nyamuk terbagi atas 5 spesies yaitu 8 nyamuk Ma. bonnae, 5 Ma. uniformis, 38 Ma. annulata, 6 Ma. annulifera dan 1 Ma. indiana. Kepadatan masing-masing nyamuk hinggap dibadan orang perjam adalah Ma. bonnae 0,31, Ma. uniformis 0,25,Ma. annulata 1,94. Ma. annulifera 0,31 dan Ma. indiana 0,06. Sedangkan kepadatan nyamukhinggap dibadan orang permalam adalah Ma. bonnae 1,33, Ma. uniformis 0,83,Ma. annulata 6,33, Ma. annulifera 1,00 dan Ma. indiana 0,17. Kelimpahan nisbi masing-masing nyamuk tertangkap yaitu Ma. bonnae 1,60%, Ma. uniformis 1,00%,Ma. annulata 6,20%, Ma. annulifera 1,00% dan Ma. indiana 0,20%. Nyamuk Mansonia spp yang tertangkap bersifat endofagik. Berdasarkan kepadatan nyamuk tertinggi dan angka dominansi spesies mencapai 3,33% maka vektor filariasis potensial di desa Ligan dan Lhok Bout adalah Mansonia annulata.
SAÚDE E SENTIDO DE VIDA: AS VIVÊNCIAS DO ENVELHECER
Authors: Espíndula Joelma Ana Gutiérrez , Ferreira Natália Nunes 
Published: July 2019

O presente estudo tem por objetivo compreender como os idosos vivenciam a saúde, sentido de vida, e como os aspectos psicossociais influenciam no processo de envelhecer. A partir da metodologia descritiva-qualitativa, tendo como fundamento a abordagem da logoterapia e analise existencial de Frankl, a pesquisa abarca uma atitude integrativa, buscando concepções de vontade do sentido, sentido da vida, liberdade da vontade. Foram realizadas cinco entrevistas com idosos do grupo de extensão Girassol da UFRR. Na análise foram identificados eixos temáticos: experiências do cotidiano da velhice, relações Interpessoais como apoio social, saúde e dificuldades corpóreas deparadas no cotidiano, percepções da finitude e desejos e/ou sonhos a serem conquistados. A maioria dos participantes menciona a família como fundamental na vida do indivíduo, seguido de amigos e grupos sociais, apoiando-os no enfrentamento do cotidiano. Alguns colaboradores ressignificam a perda de seu trabalho quando até então não tiveram uma preparação para a aposentadoria. Pode-se perceber que mesmo diante da tensão vivida pelas transformações psicossociais eles se mostram na existência entre ser e dever-ser. Eles abordaram o tema do corpo, levando-os a respeitar os limites impostos pela realidade e buscar o bem-estar e a qualidade de vida cotidianamente.
Palavras: envelhecimento, aposentadoria, aspectos psicossociais, psicogerontologia e logoterapia.

HEALTH AND MEANING OF LIFE: AGING EXPERIENCES

This study’s aim was to understand how elderly individuals experience health and the meaning of life, and how psychosocial aspects influence the aging process. Using a descriptive-qualitative methodology based on the logotherapy approach and Frankl’s existential analysis, this study has an integrative nature, seeking conceptions of will to meaning, meaning of life, and freedom to activate will. Five interviews were held with elderly individuals from the UFRR’s extension group, Girassol. The following thematic axes were identified: routine aging experiences; interpersonal relationships as social support; health and bodily difficulties encountered in daily life; and perception of finitude and desires and/or dreams to be achieved. Most participants report that family is essential in an individual’s life, followed by friends and social groups, who help them cope with everyday life. Some resignify the loss of their occupations at a time they had not yet prepared for retirement. Even though they experience tension due to psychosocial transformations, they show themselves in existence between being and must-be. They addressed the body topic, which makes them respect limitations imposed by reality, seeking wellbeing and quality of life in everyday life.
Key words: aging, retirement, psychosocial aspects, psychogerontology, and logotherapy.
Os Estados Unidos e a Reestruturação das Forças Armadas da Colômbia: Apoio Tecnológico, Transformação Organizacional e Atualização Doutrinária
Authors: Dos Santos Filho João Estevam 
Published: July 2019

Este artigo tem como objetivo analisar descritivamente o processo pelo qual os Estados Unidos envolveram-se no esforço de reestruturação da organização castrense colombiana. A pergunta que guia a pesquisa é como os Estados Unidos influenciaram na reestruturação do perfil das Forças Armadas da Colômbia entre 1998 e 2010? Para responder essa pergunta foi elaborada a seguinte hipótese: os Estados Unidos ajudaram na construção de um novo perfil de força próprio para atuação em conflitos irregulares através de: 1) fornecimento de equipamentos militares e 2) apoio à transformação organizacional. Os resultados da pesquisa corroboram a hipótese inicial.
Cotidiano, festas e festividades como momentos de aprendizagem
Authors: Monteiro Edilma Nascimento Jacinto , Monteiro Renan Jacinto 
Published: July 2019

As fotos que compõem o ensaio fotográfico fazem parte do acervo de imagens construído em trabalho de campo com ciganos Calon no estado da Paraíba, no nordeste brasileiro, entre os anos de 2013 e 2017. A pesquisa foi desenvolvida com crianças e adultos Calon, em duas comunidades ciganas Calon. A antropóloga Edilma do Nascimento traçou como objetivo de pesquisa conhecer os processos de aprendizagem entre crianças ciganas Calon, e, a partir deste objetivo, apresentamos imagens delas em diferentes perspectivas de relações no processo de aprendizagem. O recurso imagético sobre o cotidiano de vida e de como esta vida vai sendo formada diariamente está substancialmente atrelado aos valores e noções em que os grupos vivem e constroem seus elementos de pertença étnica. Assim, as fotografias surgem como uma forma de capturar o olhar sobre instantes da vida destas crianças, que se concebem num dinâmico processo de (re)conhecimento e pertencimento ao seu grupo.
Level of Satisfaction in the Use of the Wraparound Hawley and Thermoplastic Maxillary Retainers
Authors: Chagas Adenilson Silva , Freitas Karina Maria Salvatore , Cançado Rodrigo Hermont , Valarelli Fabricio Pinelli , Canuto Luiz Filiphe Gonçalves , Oliveira Renata Cristina Gobbi de , Oliveira Ricardo Cesar Gobbi de 
Published: July 2019

ABSTRACT

Objective
To compare the level of satisfaction in the use of wraparound Hawley and thermoplastic maxillary retainers.

Materials and Methods
The study sample included 70 orthodontic patients (24 males and 46 females), who were in the retention stage (mean age = 20.80 years). All patients wore the two types of maxillary retainer for 1 month each, along with a 3×3 fixed mandibular retainer. After the use of each retainer, the patients responded to a questionnaire evaluating the level of satisfaction with their use of the maxillary retainer. Intergroup comparison was performed by independent t tests. Chi-square test was used to evaluate preference for the type of retainer by gender.

Results
The thermoplastic retainer was better for swallowing and the wraparound Hawley appliance was better for hygiene and durability. The other factors evaluated (adaptation, speech, comfort, esthetics, satisfaction, and fitting) did not show significant differences between the retainers. There was also no significant difference in preference for the appliances.

Conclusions
Regarding the overall satisfaction and the preference, there was no difference between the wraparound Hawley and thermoplastic retainers. The wraparound Hawley appliance was better in hygiene and resistance than the thermoplastic retainer; and the thermoplastic appliance was better than the wraparound Hawley for swallowing fluids and saliva.
PENGEMBANGAN GAME GAMELAN SELONDING BALI BERBASIS VIRTUAL REALITY
Authors: Dewantara Ari Indrawan , Pradnyana Gede Aditra , Wirawan I Made Agus 
Published: July 2019

Gamelan adalah sebuah orkestra yang terdiri dari bermacam-macam instrumen yang terbuat dari batu, kayu, bambu, besi, perunggu, kulit, dawai, dan lain-lain dengan menggunakan laras pelog dan slendro. Salah satu cara agar generasi muda tertarik melestarikan gamelan selonding adalah dibuatkan sebuah game berbasis virtual reality, di mana penggunanya dapat berinteraksi dengan dunia virtual akanÂ membuat masyarakat antusias untuk mencoba memainkan gamelan selonding tersebut. Pengembangan Game Gamelan Selonding Berbasis Virtual Reality ini memiliki fitur bermain bebas dan bermain dengan lagu.Pengembangan produk dengan model ini dapat menghasilkan produk yang baik, karena pada setiap fase yang dilalui dapat melakukan evaluasi. Pengujian untuk mengetahui respon masyarakat setelah menggunakan Game Gamelan Selonding Berbasis Virtual Reality dilakukan dengan metode angket dan memiliki hasil dengan persentase rata-rata sebesar 88.5% yang artinya aplikasi masuk kategori sangat baik.
ANALISIS KUALITAS AIR SUMUR DI DESA CANDIKUNING KECAMATAN BATURITI
Authors: Atmaja Dewa Made 
Published: July 2019

Penelitian ini bertujuan untuk menganalisis pH, suhu warna, TDS (Total Dissolved Solid), dan kekeruhan air pada air sumur di Desa Candikuning Kabupaten Tabanan, Subjek penelitian ini adalah air sumur di Desa Candikuning, dan objek dalam penelitian ini adalah pH, suhu, warna, TDS dan kekeruhan dalam air sumur tersebut. Hasil penelitian menunjukkan bahwa kadar warna, TDS, dan kekeruhan air sumur secara berturut-turut adalah 7,8, 310C, 30,4 Skala TCU; 221,7 mg/L; 6,1 Skala NTU. Warna dan kekeruhan berada di atas batas kadar maksimal yang diperbolehkan sesuai dengan Keputusan Menteri Kesehatan RI No. 907/MENKES/SK/VII/2002, sedangkan kadar TDS masih berada di bawah batas kadar maksimal yang diperbolehkan. Hal ini menunjukkan bahwa air sumur di Desa Candikuning perlu mendapat pertimbangan untuk dikonsumsi secara langsung.
Pengembangan Alat Peraga Fisika Materi Induksi Elektromagnetik di Kelas XII SMA
Authors: Wulantri Wulantri , Ali Syamsuri 
Published: July 2019

Abstract: This study aims to develop electromagnetic induction materials electromagnetic materials in class XII SMA. This research is an R & D research that adopts the development of Borg & Gall. The data collection instrument used was a questionnaire given to a material expert, a media expert to test the feasibility of the electromagnetic induction props. The type of data produced is qualitative data which is analyzed by guidance criteria of assessment category to determine product quality. The results of this study are developed physics teaching materials electromagnetic induction in class XII SMA that are suitable for use in learning with the results of material expert validation of 77.78%, product experts 81.11% and validation of 94.72%. Based on the response of the students, percentage of feasibility of 70.83% with eligible criteria. In the field trials conducted in two schools, the average percentage of eligibility was 85.88% with very decent criteria. Abstrak: Penelitian ini bertujuan untuk mengembangkan alat peraga fisika materi induksi elektromagnetik di kelas XII SMA. Penelitian ini merupakan penelitian R&D yang mengadopsi pengembangan dari Borg & Gall. Instrumen pengumpulan data yang digunakan berupa angket yang diberikan kepada ahli materi, ahli media untuk menguji kelayakan alat peraga induksi elektromagnetik. Jenis data yang dihasilkan adalah data kualitatif yang dianalisis dengan pedoman kriteria kategori penilaian untuk menentukan kualitas produk. Hasil penelitian ini yaitu telah dikembangkan alat peraga fisika materi induksi elektromagnetik di kelas XII SMA yang layak digunakan dalam pembelajaran dengan hasil validasi ahli materi sebesar 77.78%, ahli produk sebesar 81.11% dan validasi sebesar 94.72%. Berdasarkan respon peserta didik, persentase kelayakan rata-rata sebesar 70.83% dengan kriteria layak. Pada uji coba lapangan yang dilakukan di dua sekolah mendapatkan persentase kelayakan rata-rata sebesar 85.88% dengan kriteria sangat layak.
Pembelajaran Kooperatif Tipe Think Talk Write: Pengaruhnya terhadap Kemampuan Berpikir Kritis Peserta Didik SMK SMTI Bandarlampung
Authors: Febriana Ririn , Mustari Mukarramah 
Published: July 2019

Abstract:This study aims to determine the effect of cooperative learning model Think Thalk Write on the ability of critical thinking among students of class X SMK SMTI Bandar Lampung. Research by the author is Quasi Experiment study. The study involved two groups of learners who totaled 31 students to a class experiment and 30 learners to grade control. The collection of data obtained using a test instrument. Shaped test instrument shaped essay test critical thinking skills. The results show that there are significant research critical thinking skills of learners after using cooperative learning model Think Talk Write. T test obtained tcoll > t table is 2.930 > 2.00 with a significance level of 5%. So H1 received, which indicates that there are significant cooperative learning model Think Talk Write mode on the ability of critical thinking among students of Class X. Abstrak:Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran kooperatif tipe Think Thalk Write terhadap kemampuan berpikir kritis pada peserta didik kelas X SMK SMTI Bandar Lampung. Penelitian yang penulis lakukan merupakan penelitian Quasi Eksperimen. Penelitian ini melibatkan 2 kelompok belajar peserta didik yang berjumlah 31 peserta didik untuk kelas Eksperimen dan 30 peserta didik untuk kelas kontrol. Pengumpulan data diperoleh dengan menggunakan instrument tes. Instrument tes berbentuk essay berbentuk test kemampuan berpikir kritis. Diperoleh hasil penelitian bahwa terdapat pengaruh kemampuan berpikir kritis peserta didik setelah menggunakan model pembelajaran kooperatif tipe Think Talk Write. Uji t diperoleh t hitung > ttabel yaitu 2,930 > 2,00 dengan taraf signifikan 5%. Jadi H1 diterima, yang menandakan bahwa terdapat pengaruh model pembelajaran Kooperatif Tipe Think Talk Write terhadap kemampuan berpikir kritis pada peserta didik Kelas X .
Penerapan Program Crocodile Physics Sebagai Media Pembelajaran dalam Upaya Meningkatkan Pemahaman Konsep Fisika Siswa
Authors: Novianto Abdi , Diana Nirva 
Published: July 2019

Abstract:Research In this journal aims to find out the increasing students in understanding the conception of physics through the help of media Crocodile Physics programs. The form of research used in this study is Action Research. The population in this study amounted to 69 people consisting of 37 students in class VIII of SMP 1 Bandarlampung and 32 students in 32 students of class VIII A of SMP 25 Bandarlampung. To measure the students 'understanding of the concept, there were 3 cycles of tests with multiple choice questions 20 questions in each cycle. The results showed an increase in students' understanding of physics concepts seen from the percentage of learning outcomes completeness. Cycle I percentage of completeness in class VIII I is 40.54%, cycle II is 51.35 and in cycle III is 83.78%. Cycle I percentage of completeness in class VIII A is 18.75%, cycle II is 43.24% then in cycle III is 81.25%. Through the results of the analysis and discussion, it can be concluded that the use of the Crocodile Physics program is able to increase understanding of the concept of physics.Abstrak:Penelitian Pada jurnal ini memilikitujuan untuk mengetahui meningkatnya siswa dalam memahami konsepsi fisika melalui bantuan media programCrocodile Physics. Bentuk penelitian yang digunakanpada penelitian ini adalah Action Research. Populasi dalam penelitian ini berjumlah 69 orang terdiri dari 37 peserta didik kelas VIII SMPN 1 Bandarlampung dan 32 peserta didik 32 peserta didik kelas VIII A SMPN 25 Bandarlampung. Untuk mengukur pemahaman konsep siswa dilakukan test sebanyak 3 siklus dengan soal pilihan ganda 20 soal dimasing-masing siklus.Hasil penelitian menunjukkan peningkatan pemahaman konsep fisika siswa di lihat dari presentase ketuntasan hasil belajar. Siklus I presentase ketuntasan dikelas VIII I sebesar 40,54 %, siklus II sebesar 51,35 dan pada siklus III sebesar 83,78 %. Siklus I presentase ketuntasan dikelas VIII A adalah 18,75 %, siklus II adalah 43,24 % kemudian pada siklus III adalah 81,25 %. Melalui hasil analisis dan pembahasan dapat menyimpulkan untuk penggunaan program Crocodile Physics mampu dalam meningkatnya pemahaman konsep fisika.