bluuebunny/crossref_metadata_2025_split huggingface dataset:
Finding a Balance: Reconciling the Needs of the Institution, Patient, and Genetic Counselor for Optimal Resource Utilization
Authors: Patel Devanshi , Blouch Erica L. , Rodgers‐Fouché Linda H. , Emmet Margaret M. , Shannon Kristen M. 
Published: June 2018

AbstractThe current practice of cancer genetic counseling is undergoing widespread change and scrutiny. While there are clinical resources for genetic counselors (GCs) regarding the delivery of cancer genetic services, there is limited literature regarding effective management of a genetic counseling clinical program. We have developed administrative tools to manage a large team of GCs at a single academic medical center over a period of increasing demand for genetics services, with the initial aim of decreasing wait time for urgent genetic counseling visits. Here, we describe the three main elements of the clinical operations: Balancing patient volume between GCs, scheduling tracks for both routine and urgent appointments, and a team of triaging GCs to ensure appropriate patient referrals. For each of these elements, we describe how they have been modified over time and present data to support the utility of these strategies. The preliminary evidence offered here suggests that these tools allow for an equitable distribution of patient volume between team members, as well as the timely and accurate scheduling of urgent patients. As a result of the experiences presented here, other genetic counseling programs grappling with similar issues should be aware that it is possible to shift clinical operations to serve certain patient populations in a more timely fashion while keeping both providers and GC staff satisfied.
Ecological drivers of plant diversity patterns in remnants coastal sand dune ecosystems along the northern Adriatic coastline
Authors: Tordoni Enrico , Napolitano Rossella , Maccherini Simona , Da Re Daniele , Bacaro Giovanni 
Published: June 2018

AbstractCoastal sand dunes represent one of the most fragile ecosystems in the Mediterranean basin. These habitats naturally suffer the action of several limiting factors such as sand burial, marine aerosol and low soil fertility; on the other hand, they often host species of high conservation value. Over the last decades, they have also experienced a high level of biological invasion. In this study, we sampled psammophilous vegetation in two sites in the northern Adriatic coast belonging to the Natura 2000 network to describe diversity patterns and to identify the main ecological drivers of species diversity. Plant species richness and their abundance were assessed in each plot. Differences in species composition for native and alien species were compared via PERMANOVA analysis. Species complementarity was explored by partitioning beta diversity in its spatial components (richness and replacement). A Generalized Linear Model was also computed to assess the main environmental factors that may promote invasiveness in these ecosystems. For the investigated area, our results highlight the strong differentiation in community composition both in alien and native species: in particular alien species showed on average a lower complementarity among habitats compared to native species. Specifically, communities seem to be more diversified when larger spatial scales were considered. Beta diversity in both groups appears to be more dominated by the richness component with respect to the replacement component. Furthermore, in these habitats, the occurrence of alien species was shown to be related to geomorphological predictors more than climatic variables.
Functional and ecophysiological traits of Halimione portulacoides and Sarcocornia perennis ecotypes in Mediterranean salt marshes under different tidal exposures
Authors: Duarte Bernardo , Silva Helena , Dias João Miguel , Sleimi Noomene , Marques João Carlos , Caçador Isabel 
Published: June 2018

AbstractThe present paper aims to discuss the functional and ecophysiological traits of two abundant succulent halophytes in Mediterranean salt marsh systems, considering two ecotypes differing on their tidal exposure. In Halimione portulacoides the higher root/shoot (R/S) biomass ratio verified in low inundation frequency (LF) marshes, as compared with that in high inundation frequency (HF), indicates an optimal partitioning strategy, inducing differential allocation patterns along with varying environmental factors. Conversely, Sarcocornia perennis appear to have an isometric allocation strategy, based on intrinsic biomass allocation mechanisms independent from the surrounding environmental conditions. Similarly, the photosynthetic traits appear to reflect the intrinsic ecology of the species. Sarcocornia perennis habitat adaptation to HF conditions is clearly revealed by its high photosynthetic efficiency under HF conditions. On the other hand, the cosmopolitan H. portulacoides shows no differences between ecotypes, in which concerns this trait, mostly due to the high carotenoid content of the HF ecotype, which allows this specie to counteract the stress generated during submersion. Additionally, anti‐oxidant enzymatic activities revealed that S. perennis presents a high degree of stress tolerance under HF conditions, while H. portulacoides is highly adapted to LF conditions. These functional (biomass‐related) and physiological traits determine the optimal habitats for H. portulacoides and S. perennis. While H. portulacoides optimal biomass partitioning, along with its efficient anti‐oxidant defence system, makes this species fitter to LF conditions, S. perennis isometric allocation strategy, along with a higher photosynthetic efficiency under frequent flooding conditions, provides this species the mechanisms to efficiently colonize the intertidal habitat.
Assessing the exchange of knowledge between operations management and other fields: Some challenges and opportunities
Authors: Meredith Jack R. , Pilkington Alan 
Published: June 2018

AbstractAddressing a suspicion that the field of Operations Management (OM) draws substantially more knowledge from non‐OM journals than those journals draw from OM journals in return, we studied the citations of the top 30 research journals of interest to our field. We conducted citation analyses of the three oldest OM journals over three decades in comparison to the 27 other journals representing the fields of Management, Operations Research/Management Science (OR/MS), Marketing, Practice, and Engineering. We examined both the entire 30‐year period and then each decade separately. Our suspicions were confirmed—although citations from these 27 journals to these three OM journals have increased by a factor of 7 over the three decades, we in OM still cite these journals about twenty‐five times more often than they cite our journals, giving an indication of the knowledge development and flows among these fields. We then describe some challenges for the field of OM in providing more research knowledge to other fields but also some opportunities that OM should be able to capitalize on, such as our historic ties to practice and our escalating research in strategic and organizational issues.
The Rehabilitation of Patients With Advanced Heart Failure After Left Ventricular Assist Device Placement: A Narrative Review
Authors: Eickmeyer Sarah M. , Barker Kim D. , Sayyad Anjum , Rydberg Leslie 
Published: June 2018

AbstractBecause more patients with advanced heart failure are receiving a left ventricular assist device (LVAD) as destination therapy or a bridge to transplantation, there is increasing attention on functional outcomes and quality of life after LVAD implantation. Rehabilitation providers in the acute inpatient rehabilitation setting increasingly will treat patients with an LVAD and should understand the exercise physiology, medical management, rehabilitation considerations, and outcomes after rehabilitation for patients with an LVAD. The purpose of this article is to provide the physiatrist with a comprehensive understanding of the rehabilitation of patients with advanced heart failure and LVAD implantation. Changes in relevant organ system physiology and exercise physiology after LVAD are summarized. Safety of rehabilitation and program considerations for acute inpatient rehabilitation are reviewed. Recommendations for medical management and prevention of secondary complications seen in patients with an LVAD are outlined. A discussion of outcomes after acute inpatient rehabilitation, the dual diagnosis of stroke and LVAD placement, and long‐term cognitive, functional, and quality‐of‐life outcomes after LVAD placement is presented.
Are businesses getting complacent when it comes to DDoS mitigation?
Authors: Townsley Chris 
Published: June 2018

There is no doubt that the number of distributed denial of service (DDoS) attacks is growing, as is the likelihood of any given organisation being attacked. DDoS attacks continue to grab headlines as they become more prevalent and more crippling in their effect. There is now a growing realisation among businesses that no industry is safe: any type of business with an online presence is at risk. The number of distributed denial of service (DDoS) attacks is growing, as is the likelihood of any given organisation being attacked. There is now a growing realisation among businesses that no industry is safe: any type of business with an online presence is at risk. And yet still we hear the phrase ‘it will never happen to me’. Too few organisations are taking note of the multiple warnings in the media and from the security industry, warns Chris Townsley of CDNetworks.
Instilling a culture of data security throughout the organisation
Authors: Simmonds Mike 
Published: June 2018

It has long been acknowledged that cyber-security is only as robust as its weakest link. While that could be an unpatched switch or a USB drive left in a company car park, one thing is generally consistent: the weakest part of a 21st Century business's cyber-defences is likely to be its staff. While the threat of the bad guys infiltrating a modern organisation's network may be less than first thought, behaviour that can be just as damaging and expensive to businesses is happening all around us. In fact, we may even be guilty of the contributing factors ourselves. There needs to be a shift in attitude. While implementing the right information security systems is important, organisations must also instil the right culture within the business so that employees understand and respect the importance of data security and don't put the organisation at risk, says Mike Simmonds of Axial Systems.
A combined mesowear analysis of MexicanBison antiquusshows a generalist diet with geographical variation
Authors: Díaz-Sibaja Roberto , Jiménez-Hidalgo Eduardo , Ponce-Saavedra Javier , García-Zepeda María Luisa 
Published: June 2018

AbstractBison antiquusLeidy, 1852 was one of the largest and most widely distributed megafaunal species during the Late Pleistocene in North America, giving rise to the modern plains bison in the middle Holocene. Despite the importance of the ancient bison, little is known about its feeding ecology. We employed a combination of extended mesowear, and mesowear III to infer the dietary preference and habitat use of three Mexican samples ofB. antiquus. These included two northern samples—La Piedad-Santa Ana and La Cinta-Portalitos—from the Transmexican Volcanic Belt morphotectonic Province, as well as one southern sample—Viko Vijin—from the Sierra Madre del Sur morphotectonic province. We found that the northern Mexican samples were primarily nonstrict grazers, whereas the southern sample displays a pattern consistent with mixed feeding habits. This suggests variability among the diets of the bison from these samples, caused by different paleoenvironments. This evidence complements the paleoenvironmental reconstructions in the studied localities; for the northern samples, open prairies composed of patches of woodland or shrubland and, for the southern locality, a fluvial floodplain with short-lived vegetation. In both scenarios, grasses (Poaceae) were nondominant. The dietary habits of our samples of ancient bison in Mexico are the southernmost dietary inference for the species in North America and expand our knowledge of the dietary habits ofB. antiquusduring the Late Pleistocene.
The Carceral Colony: Colonial Exploitation, Coercion, and Control in the Dutch East Indies, 1810s–1940s
Authors: van Rossum Matthias 
Published: June 2018

AbstractThis article studies the strategic disciplinary and productive function of the colonial penal system of the Dutch East Indies (1816–1942). Developing convict labour as the main punishment for minor public and labour offences, the Dutch colonial regime created an increasingly effective system of exploitation that weaved together colonial discipline, control, and coercion. This system was based on two majorcarceral connections: firstly, the interrelated development and employment of different coerced labour regimes, and, secondly, the disciplinary role of the legal-carceral regime within the wider colonial project, supporting not only the management of public order and labour control, but also colonial production systems. Punishment of colonial subjects through “administrative justice” (police law) accelerated in the second half of the nineteenth century, leading to an explosion in the number of convictions. The convict labour force produced by this carceral regime was vital for colonial production, supporting colonial goals such as expansion, infrastructure, extraction, and production. The Dutch colonial system was a very early, but quite advanced, case of a colonial carceral state.
Associations between P3a and P3b amplitudes and cognition in antipsychotic-naïve first-episode schizophrenia patients
Authors: Kruiper Caitlyn , Fagerlund Birgitte , Nielsen Mette Ø. , Düring Signe , Jensen Maria H. , Ebdrup Bjørn H. , Glenthøj Birte Y. , Oranje Bob 
Published: June 2018

AbstractBackgroundCognitive deficits are already present in early stages of schizophrenia. P3a and P3b event-related potentials (ERPs) are believed to underlie the processes of attention and working memory (WM), yet limited research has been performed on the associations between these parameters. Therefore, we explored possible associations between P3a/b amplitudes and cognition in a large cohort of antipsychotic-naïve, first-episode schizophrenia (AN-FES) patients and healthy controls (HC).MethodsSeventy-three AN-FES patients and 93 age- and gender-matched HC were assessed for their P3a/b amplitude with an auditory oddball paradigm. In addition, subjects performed several subtests from the Cambridge Neuropsychological Test Automated Battery (CANTAB).ResultsAN-FES patients had significantly reduced P3a/b amplitudes, as well as significantly lower scores on all cognitive tests compared with HC. Total group correlations revealed positive associations between P3b amplitude and WM and sustained attention and negative associations with all reaction time measures. These associations appeared mainly driven by AN-FES patients, where we found a similar pattern. No significant associations were found between P3b amplitude and cognitive measures in our HC. P3a amplitude did not correlate significantly with any cognitive measures in either group, nor when combined.ConclusionsOur results provide further evidence for P3a/b amplitude deficits and cognitive deficits in AN-FES patients, which are neither due to antipsychotics nor to disease progress. Furthermore, our data showed significant, yet weak associations between P3b and cognition. Therefore, our data do not supply evidence for deficient P3a/b amplitudes as direct underlying factors for cognitive deficits in schizophrenia.
Being versus appearing socially uninterested: Challenging assumptions about social motivation in autism
Authors: Jaswal Vikram K. , Akhtar Nameera 
Published: June 2018

Abstract
Progress in psychological science can be limited by a number of factors, not least of which are the starting assumptions of scientists themselves. We believe that some influential accounts of autism rest on a questionable assumption that many of its behavioral characteristics indicate a lack of social interest – an assumption that is flatly contradicted by the testimony of many autistic people themselves. In this article, we challenge this assumption by describing alternative explanations for four such behaviors: (a) low levels of eye contact, (b) infrequent pointing, (c) motor stereotypies, and (d) echolalia. The assumption that autistic people's unusual behaviors indicate diminished social motivation has had profound and often negative effects on the ways they are studied and treated. We argue that understanding and supporting autistic individuals will require interrogating this assumption, taking autistic testimony seriously, considering alternative explanations for unusual behaviors, and investigating unconventional – even idiosyncratic – ways in which autistic individuals may express their social interest. These steps are crucial, we believe, for creating a more accurate, humane, and useful science of autism.
Towards a fire history of European cities (late Middle Ages to late nineteenth century)
Authors: GARRIOCH DAVID 
Published: June 2018

ABSTRACT:Fires are often seen as a constant in early modern European towns, changing only in the modern era when inflammable building materials replaced wood. This article argues that the incidence, nature and risk of fire shifted repeatedly over time. Fire danger was determined not only by building materials but also by forms of construction, by the everyday uses people made of flame and by wider factors such as climatic variation and shifts in world trade and consumer demand. It was influenced by urban social and political change, including the way governments and populations responded to the risk. Responses to new fire dangers in turn helped change the way urban government functioned.
107 Using Brief Motivational Interviewing to Increase Healthy Lifestyle Habits in Overweight and Obese Adults in a Rural Family Practice Setting
Authors: McNulty Amanda 
Published: June 2018

AbstractObesity is a rapidly growing epidemic in the United States of America resulting in a multitude of comorbid conditions. Individuals living in rural areas have a higher prevalence of obesity than in urban settings. Effective treatment of obesity is needed to decrease the morbidity and mortality of this chronic disease. Using motivational interviewing (MI) techniques to address unhealthy lifestyle habits has previously proven to be effective in aiding individuals to achieve a healthier lifestyle.ObjectivesThe main objective is to determine the effectiveness of brief MI used during regular office visits and with phone follow-ups on body mass index (BMI) at the initiation of the project, as well as at the 3-month follow-up. Secondary objectives are to determine the effect brief MI has on the amount of weekly physical activity, advancing the individual to the next stage on the Transtheoretical Model of Change (TTM) continuum and determining common barriers to leading a healthy lifestyle in a rural adult population.MethodParticipants (n=15) were recruited using a convenience sampling method from the primary care practice. Using a pretest/posttest design, individuals were asked to complete a survey regarding their amount of weekly exercise, their perceived stage of change and their barriers to healthy lifestyle choices. A pre- and post-intervention BMI was collected. One in-office brief MI session and two monthly phone sessions were conducted, each lasting not longer than ten minutes.ResultsA total of 14 participants, mostly female (67%), aged 36 to 45 years old (33%), Caucasian (73.3%), and had some college education (40%), completed the study. It was hypothesized that brief MI would result in decreased BMI, increased exercise and advancement along the TTM continuum. No significant difference in the pre-and post -intervention BMI ([M=37.88, SD=9.15] vs [M=37.01, SD=9.37]); t (27)=0.25, p=0.801 was found. Many participants (n=10), however, had a decrease in BMI. The difference in weekly activity (M=644.2 min vs M=268.57 min) was not found to be statistically significant; t (27)=1.40, p=0.17. An increase in readiness to change was noted, but, was not significant (p =0.52). Of 34 responses, chronic pain or health conditions (n=10) and scheduling conflicts (n=7) were the two top cited reasons for not practicing a healthylifestyle.ConclusionsThis QI project did not demonstrate statistically significant improvement in BMI, weekly exercise or readiness to change after three months of brief MI. It is important to note, however, that many individuals did experience an overall decrease in BMI. It is also promising to note that more individuals were participating in healthylifestyle activities more frequently post-intervention when analyzed on the TTM continuum. Further studies are needed to analyze the most effective strategies to assist individuals in rural settings to make healthier lifestyle choices.Funding AcknowledgementsNo funding.
111 A Novel Dual-Channel Deep Transcranial Magnetic Stimulator for Major Depressive Disorder
Authors: Harel Eiran V , Shmuel Dikla , Antler Daniel , Katz Dana , Pushkarski Elina , Ais Ezekiel , Schvartz Anna , Tendler Aron , Roth Yiftach , Zangen Abraham , Levkovitz Yechiel 
Published: June 2018

AbstractBackgroundRepetitive deep transcranial magnetic stimulation (dTMS) is efficacious for treatment resistant major depressive disorder (TRD) with the H1 coil by stimulating the prefrontal cortex, left more than right, at high frequency. Theoretically, the efficacy of dTMS could be optimized by simultaneously stimulating the right and left lateral prefrontal cortices (PFC) with different frequencies. This study tested the efficacy of a novel dual-channel dTMS stimulator with dual dTMS coils, in patients with TRD.MethodsThis study recruited forty-seven outpatients diagnosed with TRD, age 18-65, Hamilton Depression Rating Scale (HDRS-21) score ≥25. Each patient received 20 open label treatment sessions, five days a week for 4 consecutive weeks. Treatments were administered with the dual-channel stimulator (Brainsway Multiway dTMS device) using two channels: a. 10 Hz over the left PFC. b. 1 Hz over the right PFC. Primary and secondary efficacy outcome measures were the change in HDRS-21 score and response/remission rates at week 5, respectively.ResultsThe HDRS-21 score decreased from an average of 25.94 to 14.69 (P<0.001). Thirty-six patients completed four weeks of treatment. Of them, seventeen (47%) responded (HDRS-21 score decrease of ≥ 50% from their initial score) and eight (22%) remitted (HDRS-21 score of < 10 at the end of the study).DiscussionThis open study shows promising results for multichannel simultaneous dTMS treatment of TRD using the Brainsway Multiway Device. Further randomized controlled studies are necessary to aid the high number of patients with TRD.Funding AcknowledgementsBrainsway Ltd.