bluuebunny/crossref_metadata_2025_split huggingface dataset:
Water‐immersion effect on radial crack initiation behavior in a fiber‐bundle‐reinforced epoxy cylinder with graphene in the interfacial region
Authors: Yang Kang , Yang Bin , Wang Jinling , He Liang , Wan Yun , Xuan Fu‐Zhen 
Published: September 2018

AbstractThe long‐term durability of polymer composites serviced under moist, high‐temperature conditions is a major concern in many industries. As an attempt, we filled 0.3 wt % graphene in a fiber–matrix interfacial region between glass fibers, carbon fibers, glass–carbon hybrid fibers, and epoxy resin to enhance the mechanical performance of the composites under water‐immersion conditions. The mass increment was recorded periodically while the specimens were immersed in 25 and 70°C water. Axial compression tests were carried out to investigate the initiation behavior of the interfacial radial microcracks after immersion. The results show that the equilibrium moisture content and permeability of the graphene‐filled interfaces were larger than that of the virgin specimens. The interfacial radial crack initial stress decreased sharply after immersion; however, the addition of graphene in the fiber–matrix interface help to decrease this tendency in 70°C water. The observed rough surfaces of the graphene‐coated fibers after breakage in the compression tests verified the feasibility of this method. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47080.
Some pyrazoles derivatives: Potent carbonic anhydrase, α‐glycosidase, and cholinesterase enzymes inhibitors
Authors: Turkan Fikret , Cetin Adnan , Taslimi Parham , Gulçin İlhami 
Published: September 2018

AbstractA series of substituteed pyrazol‐4‐yl‐diazene derivatives were found to be effective inhibitors against α‐glycosidase, cytosolic carbonic anhydrase I and II isoforms (hCA I and II), butyrylcholinesterase (BChE), and acetylcholinesterase (AChE) with Ki values in the range of 33.72 ± 7.93 to 90.56 ± 27.52 nM for α‐glycosidase, 1.06 ± 0.16 to 9.83 ± 0.74 nM for hCA I, 0.68 ± 0.12 to 7.16 ± 1.14 nM for hCA II, 44.66 ± 10.06 to 78.34 ± 17.83 nM for AChE, and 50.36 ± 13.88 to 88.36 ± 20.03 nM for BChE, respectively. Recently, inhibition of these metabolic enzymes has been considered as a promising factor for pharmacologic intervention in a diversity of disturbances, such as diabetes, glaucoma, obesity, epilepsy, cancer, and neurodegenerative diseases.
Preparation and Properties of a Polycyclic p‐Quinodimethane with Two Oxygen Bridges and its Radical Cation in Comparison with the Isomeric o‐Quinodimethane
Authors: Sato Chihiro , Suzuki Shuichi , Okada Keiji , Kozaki Masatoshi 
Published: September 2018

AbstractWe prepared an electron‐rich p‐quinodimethane compound, 2,9‐dibromo‐7,14‐dimesityl‐5,12‐dioxapentacene (1). The quinoidal character was clarified by bond‐length alternation in the central ring. Clear vibrational structures in both absorption and emission bands and small Stokes shift indicate the rigid dioxapentacene framework. The reversible redox waves of 1 were observed at +0.14 and +0.69 V vs. Fc+/Fc, respectively. The radical cation salt 1⋅+⋅SbF6− was successfully isolated and characterized by means of X‐ray structural analysis and ESR and UV/Vis‐near infrared absorption spectroscopies. The molecular structure and electronic properties of the neutral and radical cation species were compared to those of the isomeric o‐quinodimethane.
Methane Hydroxylation with Water as an Electron Donor under Light Irradiation in the Presence of Reconstituted Membranes Containing both Photosystem II and a Methane Monooxygenase
Authors: Ito Hidehiro , Kondo Ryuichi , Yoshimori Kosei , Kamachi Toshiaki 
Published: September 2018

AbstractMethane/methanol conversion is one of the most important chemical reactions. Methane monooxygenases from methanotrophs are enzymes that catalyze methane/methanol conversion under mild conditions. Here we report the reconstitution of purified photosystem II (PSII) from Thermosynechococcus elongatus BP‐1 into the membrane fraction containing particulate methane monooxygenase (pMMO) from Methylosinus trichosporium OB3b. Photoinduced hydroxylation of methane to methanol was successfully achieved by using the PSII‐reconstituted membrane containing pMMO under light irradiation. This result indicates that the sequential redox chain from PSII through the quinone pool to pMMO can be constructed and that water can serve as the electron donor for methane hydroxylation under irradiation with light. pMMO in the membrane fraction produced hydrogen peroxide as a byproduct when an electron donor was added for methane hydroxylation, whereas under light irradiation conditions the PSII‐reconstituted membrane containing pMMO did not generate hydrogen peroxide. Optimization of the electron‐transfer rate can easily be achieved with this system by tuning the light intensity.
Idiopathic membranoproliferative glomerulonephritis treated with mycophenolate mofetil
Authors: Koratala Abhilash , Malpartida Freddy R. , Lee Loy Justin , Zeng Xu 
Published: September 2018

Key Clinical Message“Idiopathic” membranoproliferative glomerulonephritis (MPGN) is rare compared to secondary forms and usually a progressive disease. Studies evaluating the role of steroids were primarily done in children, and the data are sparse in adults. Mycophenolate mofetil is effective and can be used as a steroid‐sparing agent in the treatment of idiopathicMPGN.
Gendered and racialized social expectations, barriers, and delayed breast cancer diagnosis
Authors: Kim Sage J. , Glassgow Anne Elizabeth , Watson Karriem S. , Molina Yamile , Calhoun Elizabeth A. 
Published: September 2018

BackgroundBlack women are more likely to be diagnosed at a later stage of breast cancer in part due to barriers to timely screening mammography, resulting in poorer mortality and survival outcomes. Patient navigation that helps to overcome barriers to the early detection of breast cancer is an effective intervention for reducing breast cancer disparity. However, the ability to recognize and seek help to overcome barriers may be affected by gendered and racialized social expectations of women.MethodsData from a randomized controlled trial, the Patient Navigation in Medically Underserved Areas study, were used. The likelihood of obtaining a follow‐up screening mammogram was compared between women who identified ≥1 barriers and those who did not.ResultsOf the 3754 women who received the Patient Navigation in Medically Underserved Areas navigation intervention, approximately 14% identified ≥ 1 barriers, which led to additional navigator contacts. Consequently, those women who reported barriers were more likely to obtain a subsequent screening mammogram. Black women, women living in poverty, and women with a higher level of distrust were less likely to report barriers.ConclusionsMinority women living in poverty have always been the source of social support for others. However, gendered and racialized social expectations may affect the ways in which women seek help for their own health needs. A way to improve the effectiveness of navigation would be to recognize how minority women's gender images and expectations could shape how they seek help and support. A report of no barriers does not always translate into no problems. Proactive approaches to identify potential barriers may be beneficial.
Second‐Order Nonlinear Optical Tensor Coefficients of LiXTe2 (X = Al, Ga, In) Chalcopyrite Semiconductors
Authors: Kumar Virendra , Chandra Satish 
Published: September 2018

AbstractUsing solid‐state theory of plasma oscillations, simple relations are proposed for the calculation of the second‐order nonlinear optical (NLO) tensor coefficients of LiXTe2 (X = Al, Ga, In) semiconductors. The values of bond lengths, energy gaps, dielectric constant, and NLO tensor coefficients of Li–Te and X–Te bonds and their total contribution to LiXTe2 compounds are calculated at zero frequency. The calculated results are in reasonable agreement with the known and reported results.
Nitrogen enrichment alters nutrient resorption and exacerbates phosphorus limitation in the desert shrub Artemisia ordosica
Authors: Zheng Jing , She Weiwei , Zhang Yuqing , Bai Yuxuan , Qin Shugao , Wu Bin 
Published: September 2018

AbstractIncreasing nitrogen (N) deposition and precipitation are major drivers of global changes that are expected to influence plant nutrient resorption in desert ecosystems, where plant growth is often nutrient and water limited. However, knowledge on the effects of increased N and precipitation on them remain poorly understood. This study determined the effects of increased N (ambient, 60 kg N ha−1 year−1) and water supply (ambient, +20%, +40%), and their combination on the leaf nutrient resorption of Artemisia ordosica, a dominant shrub in the Mu Us Desert of northern China. After 2 years of treatments, only N addition significantly decreased the N resorption efficiency of A. ordosica. Both N and water addition had no effect on the phosphorus (P) resorption efficiency of this shrub, and there were no interactive effects of N and water availability on shrub nutrient resorption. The responses of shrub leaf N:P ratio tended to saturate as soil available N:P increased. The aboveground net primary productivity of A. ordosica was positively correlated with leaf P resorption efficiency, rather than N resorption efficiency. Our results suggest that N addition exacerbated the P limitation of the shrub growth and played a more fundamental role than water addition in controlling the nutrient resorption process of the desert shrub A. ordosica. This information contributes to understand the relationship between nutrient conservation strategy and plant growth of desert shrub species under global environmental changes.
Value comparison between FRT and DVS functions on renewable energy
Authors: Jozuka Takeshi , Iriguchi Tsuyoshi , Komami Shintaro 
Published: September 2018

AbstractAlthough FRT capability is claimed in Japanese grid code for RE, DVS capability is not. In some European countries, not only FRT but also DVS is claimed. Whether this choice of our grid code is pragmatically adequate or not? To answer the question, it is necessary to evaluate FRT and DVS capabilities. But the past studies only evaluated qualitative merit of FRT and DVS, or evaluated quantitative merit on fictional system models. Since the authors intend to evaluate FRT and DVS capabilities in existing power system of Japan, some method for the evaluation must be invented. For the evaluation, values of FRT and DVS capabilities are evaluated by reduction amount of stabilizing equipment (i.e. SVC in the paper). The evaluation based on strict optimal SVC disposition is quite difficult, because existing power system must be adequately modeled, because number of SVCs is large and because every power flow conditions must be considered. However, semi‐optimal SVC disposition can be calculated as shown in the paper. As the result, value of FRT is quite larger than value of DVS. And then, our grid code is proved as pragmatically adequate, except some flaw in claimed FRT design that is introduced in the paper.
A new dc‐bus‐voltage‐robust sensorless control for switched reluctance motors
Authors: Kamiyama Tatsuya , Yoshida Toshiya 
Published: September 2018

AbstractThis article describes a new sensorless control technique for switched reluctance motors. The proposed system injects voltage pulses into the two unexcited windings and observes their currents. Timing signals for commutating the inverter are generated by comparing these currents. Almost no predetermined parameters are required for system setup. In the experiments, the proposed drive system is verified at 1000 and 3000 min−1 under load. The system achieves acceptable commutation timing accuracy and provides robustness to dc‐link voltage ripple and to output torque.
Randomized double‐blind clinical studies of ularitide and other vasoactive substances in acute decompensated heart failure: a systematic review and meta‐analysis
Authors: Mitrovic Veselin , Forssmann Wolf‐Georg , Schnitker Jan , Felix Stephan B. 
Published: September 2018

AbstractAimsAcute decompensated heart failure (ADHF) has a poor prognosis and limited treatment options. No direct comparisons between ularitide—a synthetic natriuretic peptide being evaluated in ADHF—and other vasoactive substances are available. The aim of this meta‐analysis was to determine haemodynamic effect sizes from randomized double‐blind trials in ADHF.Methods and resultsEligible studies enrolled patients with ADHF requiring hospitalization and haemodynamic monitoring. Patients received 24–48 h of infusion with a vasoactive substance or comparator. Primary outcome measure was pulmonary artery wedge pressure (PAWP). Treatment effects were quantified as changes from baseline using mean differences between study drug and comparator. Results were analysed using random‐effects (primary analysis) and fixed‐effects meta‐analyses. Twelve randomized, double‐blind studies were identified with data after 3, 6, and 24 h of treatment (n = 622, 644, and 644, respectively). At 6 h, significant PAWP benefits for ularitide over placebo were seen (Hedges' g effect size, −0.979; P < 0.0001). On meta‐analysis, treatment difference between ularitide and pooled other agents was statistically significant (−0.501; P = 0.0303). Effect sizes were numerically higher with ularitide than other treatments at 3 and 24 h. After 6 h, a significant difference in effect size between ularitide and all other treatments was observed for right atrial pressure (Hedges' g, −0.797 for ularitide and −0.304 for other treatments; P = 0.0274).ConclusionsAfter 6 h, ularitide demonstrated high effect sizes for PAWP and right atrial pressure. Improvements in these parameters were greater with ularitide vs. pooled data for other vasoactive drugs.
Glycosylation and metastases
Authors: Josic Djuro , Martinovic Tamara , Pavelic Kresimir 
Published: September 2018

AbstractThe change of cellular glycosylation is one of the key events in malignant transformation and neoplastic progression, and tumor‐related glycosylation alterations are promising targets in both tumor diagnosis and therapy. Both malignant transformation and neoplastic progression are the consequence of gene expression alterations and alterations in protein expression. Micro environmental factors such as extracellular matrix (ECM) also play an important role in their growth and metastasis. Tumor‐associated glycans are important biomarker candidates for cancer diagnosis and prognosis, and analytical methods for their detection were developed recently. Glycoproteomics that use mass spectrometry for identification of cancer antigens and structural analysis of glycans play a key role in the investigation of changes of glycosylation during malignant transformation and tumor development and metastasis. Deep understanding of glycan remodeling in cancer and the role of glycosyltransferases that are involved in this process will require a detailed profiling of glycosylation patterns of tumor cells, and corresponding analytical methods for their detection were developed.
Pt Supported on Carbon‐coating Antimony Tin Oxide as Anode Catalyst for Direct Methanol Fuel Cell
Authors: Yang D.‐H. , Sui X.‐L. , Zhao L. , Huang G.‐S. , Gu D.‐M. , Wang Z.‐B. 
Published: September 2018

AbstractA qualified support material for Pt must has numerous deposition sites for Pt nanoparticles and great electrical conductivity. Metal oxide materials are potential support materials for Pt nanoparticles. However, they have less deposition sites for Pt and worse electronic conductivity than carbon. Carbon over the surface of metal oxide materials can improve the above shortage. In this paper, antimony tin oxide (ATO) coated by carbon layer has been successfully prepared by plasma enhanced chemical vapor deposition method (PECVD). PECVD can provide a brief approach to enwrap metal oxide with carbon at low temperatures. Besides, it becomes easier to control the amount of carbon by the PECVD to create much more two‐phase interface for Pt deposition. The carbon layer promotes the electronic conductivity of ATO and provides more deposition sites for platinum nanoparticles, which directly influence the size of Pt nanoparticles as well as the electrochemical active surface areas. The as‐prepared catalyst exhibits excellent activity for methanol oxidation reaction (MOR), which is twice of that of the commercial Pt/C catalyst. Meanwhile, it has better stability than the commercial Pt/C.
How important are fixed effects and time trends in estimating returns to schooling? Evidence from a replication of Jacobson, Lalonde, and Sullivan, 2005
Authors: Dynarski Susan , Jacob Brian , Kreisman Daniel 
Published: September 2018

SummaryA substantial and rapidly growing literature has developed around estimating earnings gains from 2‐year college degrees using administrative data. These papers almost universally employ a person‐level fixed‐effects strategy to estimate earnings premia net of fixed attributes. We note that the seminal piece on which these papers build—Jacobson, Lalonde, & Sullivan, Journal of Econometrics, 2005, 125(1–2), 271–304—provides theoretical and empirical evidence for the importance of additionally differencing out individual time trends. The subsequent literature has not followed suit. Through replication we ask whether this matters. We show that it does, and further that these person‐level time trends need not be computationally burdensome in large administrative data. We recommend them as a unifying econometric standard for future work.
Chinese Women in Both the United States and Hong Kong Have Cortical Microstructural Advantages and More Trabecular Plates Compared With White Women
Authors: Sum Melissa , Zhu Tracy Y , Zhou Bin , Zhang Zhendong , Bilezikian John P , Guo X Edward , Qin Ling , Walker Marcella 
Published: September 2018

ABSTRACTWe cross‐sectionally compared racial differences in bone quality between Chinese women in the United States (US) and Hong Kong (HK) with white women. A total of 514 women were included. We measured bone geometry, mass, microstructure, and stiffness by high‐resolution peripheral quantitative computed tomography (HR‐pQCT), individual trabecula segmentation (ITS), and microfinite element analysis (μFEA). After adjustment for age and body mass index (BMI), premenopausal Chinese women in the US and HK had smaller bone area but greater radial cortical (Ct.) thickness and Ct. and trabecular (Tb.) volumetric bone mineral density (vBMD) versus white women but did not differ from each other. At the radius, Tb. number was lower and spacing greater in Chinese women from HK and the US versus white women, whereas Chinese women did not differ from each other. Tb. thickness was highest in Chinese women from HK, intermediate in Chinese‐Americans, and lowest in white women. Chinese women had more trabecular plates versus white women, leading to greater age‐ and BMI‐adjusted stiffness for premenopausal Chinese women in HK and the US (both p < 0.05) versus white women. Tibial differences were similar in premenopausal women; analogous trends in microstructure were present in postmenopausal women at the tibia, although stiffness did not differ. In contrast, at the radius, cortical, plate‐to‐rod ratio, and stiffness were similar between postmenopausal HK and white women. Adjusting for age, weight, and height rather than age and BMI tended to reduce differences in bone size and Tb. parameters but accentuate cortical differences such that Chinese premenopausal women in both locations and postmenopausal women from HK had higher stiffness at both skeletal sites compared with white women. Compared with white women, Chinese women in the US and HK have vBMD and microstructural advantages leading to higher or similar mechanical competence in pre‐ and postmenopausal women, respectively, despite smaller bone size. © 2018 American Society for Bone and Mineral Research.
Long noncoding RNA PAGBC contributes to nitric oxide (NO) production by sponging miR‐511 in airway hyperresponsiveness upon intubation
Authors: Li Ling‐Xia , Li Yuan‐Jun , He Jia‐Xuan 
Published: September 2018

AbstractBackground and ObjectivesIn this study, we aimed to study the molecular mechanisms underlying the symptoms of hyperresponsiveness during intubation.MethodThe value of circulating long noncoding RNA (lncRNA)‐prognosis‐associated gallbladder cancer (PAGBC) in the prediction of hyperresponsiveness upon intubation during general anesthesia was evaluated via the receiver operating characteristic analyses of serum miR‐511, serum PAGBC, and serum nitric oxide (NO). In addition, the possible association between lncRNA‐PAGBC/NOS1 messenger RNA (mRNA) and miR‐511 was further validated via real‐time quantitative polymerase chain reaction, immunohistochemistry assay, computational analysis, and luciferase assay. Enzyme‐linked immunosorbent assay and Western blot analysis were also conducted to establish the regulatory relationship among PAGBC, miR‐511, and NO synthase 1 (NOS1).ResultsCompared with circulating miR‐511 and serum NO, circulating PAGBC was associated with a higher predictive value. In addition, a negative correlation was found between serum miR‐511 and serum PAGBC (multicorrelation coefficient: −0.5) as well as between serum miR‐511 and serum NO (multicorrelation coefficient: −0.6). In addition, both lncRNA‐PAGBC and NO were decreased in patients with hyperresponsiveness, whereas the levels of miR‐511 and NOS1 in these patients were similar to those in normal patients. Furthermore, our computational analyses and luciferase assays validated the direct binding between miR‐511 and lncRNA‐PAGBC, whereas NOS1 mRNA was identified as a virtual target gene of miR‐511. Moreover, in the presence of lncRNA‐PAGBC, we also observed an evident increase in the levels of NOS1 and NO accompanied by an obvious decrease of miR‐511 expression.ConclusionLncRNA‐PAGBC downregulated the expression of miR‐511, which in turn upregulated the expression of NOS1 mRNA and led to the increase in NOS1 expression, thus leading to the inhibited responsiveness (normal‐responsiveness rather than hyperresponsiveness) to intubation in patients.
The association of hemocyte profile and obstructive sleep apnea
Authors: Fan Zeqin , Lu Xiaoxia , Long Hong , Li Taoping , Zhang Yanhong 
Published: September 2018

BackgroundThe hemocyte profile is one of the most frequently requested clinical laboratory tests. However, the analysis of blood cell indexes of obstructive sleep apnea (OSA) patients in previous studies was not comprehensive. And, this study aimed to fully analyze the blood routine in OSA patients.MethodsA retrospective study was conducted on 1087 male patients, who were admitted to the sleep center of Nanfang Hospital from May 2013 to February 2018. According to the apnea hypopnea index (AHI), patients were divided into four groups: control group (AHI < 5, n = 135), mild OSA (5 ≦ AHI < 15, n = 185), moderate OSA (15 ≦ AHI < 30, n = 171), and severe OSA (AHI ≧ 30, n = 596). Data collected included sleep parameters, complete blood routine, body mass index (BMI), age, and comorbidities.ResultsIn our study, leukocytes, neutrophils, lymphocytes, monocytes, eosinophils, basophils, erythrocytes, hemoglobin, hematocrit, platelets, MPV, and PDW‐SD were statistically significant among the four groups based on AHI (P < 0.05), but no significant differences were found in MCV, RDW‐SD, N/L, and P/L ratio (P > 0.05). Neutrophils, lymphocytes, monocytes, eosinophils, basophils, hemoglobin, hematocrit, platelets, and MPV were significantly correlated with AHI. Moreover, multiple linear regression analysis demonstrated that hematocrit (β = 73.254, P = 0.001), neutrophils (β = 1.414, P = 0.012), and lymphocytes (β = 4.228, P < 0.001) were independently associated with AHI.ConclusionNeutrophils, lymphocytes, and hematocrit were independently associated with OSA severity. And combining these three blood cell indicators could contribute to the diagnosis of OSA.