bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nocturnal Convection Initiation during PECAN 2015
Authors: Weckwerth Tammy M. , Hanesiak John , Wilson James W. , Trier Stanley B. , Degelia Samuel K. , Gallus William A. , Roberts Rita D. , Wang Xuguang 
Published: July 2019

AbstractNocturnal convection initiation (NCI) is more difficult to anticipate and forecast than daytime convection initiation (CI). A major component of the Plains Elevated Convection at Night (PECAN) field campaign in the U.S. Great Plains was to intensively sample NCI and its near environment. In this article, we summarize NCI types observed during PECAN: 1 June–16 July 2015. These NCI types, classified using PECAN radar composites, are associated with 1) frontal overrunning, 2) the low-level jet (LLJ), 3) a preexisting mesoscale convective system (MCS), 4) a bore or density current, and 5) a nocturnal atmosphere lacking a clearly observed forcing mechanism (pristine). An example and description of each of these different types of PECAN NCI events are presented. The University of Oklahoma real-time 4-km Weather Research and Forecasting (WRF) Model ensemble forecast runs illustrate that the above categories having larger-scale organization (e.g., NCI associated with frontal overrunning and NCI near a preexisting MCS) were better forecasted than pristine. Based on current knowledge and data from PECAN, conceptual models summarizing key environmental features are presented and physical processes underlying the development of each of these different types of NCI events are discussed.
Our Skill in Modeling Mountain Rain and Snow is Bypassing the Skill of Our Observational Networks
Authors: Lundquist Jessica , Abel Mimi Rose , Gutmann Ethan , Kapnick Sarah 
Published: July 2019

AbstractIn mountain terrain, well-configured high-resolution atmospheric models are able to simulate total annual rain and snowfall better than spatial estimates derived from in situ observational networks of precipitation gauges, and significantly better than radar or satellite-derived estimates. This conclusion is primarily based on comparisons with streamflow and snow in basins across the western United States and in Iceland, Europe, and Asia. Even though they outperform gridded datasets based on gauge networks, atmospheric models still disagree with each other on annual average precipitation and often disagree more on their representation of individual storms. Research to address these difficulties must make use of a wide range of observations (snow, streamflow, ecology, radar, satellite) and bring together scientists from different disciplines and a wide range of communities.
Differing Responses of the Diurnal Cycle of Land Surface and Air Temperatures to Deforestation
Authors: Chen Liang , Dirmeyer Paul A. 
Published: July 2019

ABSTRACTRecent studies have shown the impacts of historical land-use land-cover changes (i.e., deforestation) on hot temperature extremes; contradictory temperature responses have been found between studies using observations and climate models. However, different characterizations of surface temperature are sometimes used in the assessments: land surface skin temperature Ts is more commonly used in observation-based studies while near-surface air temperature T2m is more often used in model-based studies. The inconsistent use of temperature variables is not inconsequential, and the relationship between deforestation and various temperature changes can be entangled, which complicates comparisons between observations and model simulations. In this study, the responses in the diurnal cycle of summertime Ts and T2m to deforestation are investigated using the Community Earth System Model. For the daily maximum, opposite responses are found in Ts and T2m. Due to decreased surface roughness after deforestation, the heat at the land surface cannot be efficiently dissipated into the air, leading to a warmer surface but cooler air. For the daily minimum, strong warming is found in T2m, which exceeds daytime cooling and leads to overall warming in daily mean temperatures. After comparing several climate models, we find that the models agree in daytime land surface (Ts) warming, but different turbulent transfer characteristics produce discrepancies in T2m. Our work highlights the need to investigate the diurnal cycles of temperature responses carefully in land-cover change studies. Furthermore, consistent consideration of temperature variables should be applied in future comparisons involving observations and climate models.
Contrasting Pre-Mei-Yu and Mei-Yu Extreme Precipitation in the Yangtze River Valley: Influencing Systems and Precipitation Mechanisms
Authors: Wang Xiaokang , Dong Xiquan , Deng Yi , Cui Chunguang , Wan Rong , Cui Wenjun 
Published: July 2019

Abstract
The mei-yu season over the Yangtze–Huai Rivers basin, typically occurring from mid-June to mid-July, is one of three heavy-rainfall periods over China and can contribute 50% of the annual precipitation. In this study, the first and second heaviest daily precipitation events at the Wuhan station have been selected to represent typical mei-yu and pre-mei-yu precipitation events where the differences in the atmospheric thermodynamic characteristics, precipitation nature, influencing systems, and mechanisms are investigated. During the mei-yu case, moist air mainly came from the South China Sea. Precipitation occurred south of the mei-yu front where abundant moisture and favorable thermodynamic conditions were present. The main influencing systems include a stable blocking pattern and strong and stable western Pacific subtropical high in the midtroposphere, and a small yet intense mesoscale cyclonic vortex in the low troposphere. Rainfall in Wuhan was continuous, caused by a well-organized convective line. A heavy rainband was located along the narrow band between the elongated upper-level jet (ULJ) and the low-level jet (LLJ) where the symmetric instability was found in the midtroposphere near Wuhan. Quite differently, for the pre-mei-yu precipitation case, moist air primarily came from the Beibu Gulf and the Bay of Bengal. Precipitation happened in the low-level convective instability region, where a short-wave trough in the midtroposphere and a mesoscale cyclonic vortex in the low-troposphere were found. Precipitation in Wuhan showed multiple peaks associated with independent meso-β-scale convective systems. A rainstorm occurred at the exit of the LLJ and the right entrance of the ULJ, where convective instability exited in the mid- to low troposphere.
Regional and Temporal Variability of Lateral Mixing in the North Atlantic
Authors: Bolton Thomas , Abernathey Ryan , Zanna Laure 
Published: July 2019

AbstractGeostrophic eddies contribute to the mixing of heat, carbon, and other climatically important tracers. A passive tracer driven by satellite-derived surface velocity fields is used to study the regional and temporal variability of lateral eddy mixing in the North Atlantic. Using a quasi-Lagrangian diffusivity diagnostic, we show that the upstream region (80°–50°W) of the Gulf Stream jet exhibits a significant mixing barrier (with diffusivity of ≈1 × 103 m2 s−1), compared to the downstream region (50°–10°W), which displays no mixing suppression (≈10 × 103 m2 s−1). The interannual variability is 10%–20% of the time mean in both regions. By analyzing linear perturbations of mixing-length diffusivity expression, we show that the across-jet mixing in the upstream region is driven by variations in the mean flow, rather than eddy velocity. In the downstream region, both the mean flow and eddy velocity contribute to the temporal variability. Our results suggest that an eddy parameterization must take into account the along-jet variation of mixing, and within jets such diffusivities may be a simple function of jet strength.
Perception of social support and psychotic symptoms among persons with schizophrenia: A strategy to lessen caregiver burden
Authors: Peng Man-Man , Zhang Tian-Ming , Liu Ke-Zhi , Gong Ke , Huang Chao-Hua , Dai Guang-Zhi , Hu Shi-Hui , Lin Fu-Rong , Chan Sherry Kit Wa , Ng Siuman , Ran Mao-Sheng 
Published: July 2019

Background: Improving patients’ perception of social support is significant not only for their re-adaptation to life but also for alleviating caregivers’ burden. Aim: This study aims to examine an integrated model regarding social support, psychotic symptoms and caregiver burden. Methods: Persons with schizophrenia ( N1 = 300) and their family caregivers ( N2 = 300) in Xinjin County, Chengdu, China, completed the survey to report their demographics, patients’ perception of social support (Duke Social Support Index), psychotic symptoms (Positive and Negative Syndrome Scale) and caregiver burden (Burden Scale for Family Caregivers, Short Version). Structural equation modelling was utilised to test the proposed model. Results: The degree of caregiver burden differed significantly within subgroups of patients’ gender and education, as well as caregivers’ gender, education and employment. Caregiver burden was negatively related to patients’ age and household income. Social interaction partially mediated the relationship between instrumental and subjective social support (total effect = 0.451, p < .01). Subjective social support fully mediated the impact of social interaction on psychotic symptoms (total effect = −0.099, p < .05). In the final model, instrumental social support was positively associated with social interaction ( p < .001) and increased subjective social support ( p < .05). Increased subjective social support showed correlation with a lower degree of psychotic symptoms ( p < .01), which was related to a lower level of caregiver burden ( p < .001). Conclusion: This study shows the associations of patients’ social support with psychotic symptoms and caregiver burden. Culture-specific psychosocial interventions should be provided for both patients and caregivers to enrich external support and reduce psychotic symptoms and caregivers’ burden within the health care environment.
Romiplostim as a transfusion saving strategy in 20 patients after heart or lung transplantation: a single centre before-after pilot study
Authors: Vourc’h Mickael , Senage Thomas , Lepoivre Thierry , Volteau Christelle , Fortuit Camille , Pattier Sabine , Guimbretiere Guillaume , Roussel Jean-Christian , Rozec Bertrand 
Published: July 2019

Background: Thrombocytopenia is a common disorder after heart or lung transplantation. Platelet transfusion is often required to maintain haemostasis but represents a specific cause of morbidity and mortality in this setting including alloimmunisation and graft rejection. Study design and methods: As part of a health-care quality improvement project, in a single-centre before–after pilot study, the relevance of a platelet transfusion saving strategy based on romiplostim administration after transplantation was assessed in patients with platelet count <100 × 109/L. Transfusions on days 28 and 90 were compared using propensity matched score for adjustment of demographic characteristics at baseline. The primary outcome was platelet transfusion until day 28 after transplantation. Results: Ninety-three patients were analysed (73 before vs. 20 after). The median [interquartile range] number of platelet concentrate was 1 [0;4.0] before versus 0.5 [0;2.0] in the after period, mean difference 0.5 confidence interval 95% [−0.7 to 1.7], p  = 0.39. On day 28, median [interquartile range] red blood cell transfusion was significantly higher in the before versus the after period, 7 [2.0;13.5] versus 6 [1.5;8.5], mean difference 3.2 CI 95% [0.4-6.0], p = 0.02. At 6 months, the rate of patients with de novo anti-human leukocyte antigen alloimmunisation was 45% before versus 53% in the after period (p = 0.56). Deep venous thrombosis was detected in nine patients (12%) before versus seven patients (35%) in the after period (p = 0.04). Conclusion: Romiplostim did not significantly reduce platelet transfusion after heart or lung transplantation. Its relevance and safety in a global transfusion strategy remains to be studied in this setting in a large randomised study.
Hybrid versus in vitro fenestration for preserving the left subclavian artery in patients undergoing thoracic endovascular aortic repair with unfavorable proximal landing zone
Authors: Wang Maohua , Dong Dianning , Yuan Hai , Wang Mo , Wu Xuejun , Zhang Shiyi , Zhong Zhenyue , Jin Xing , Zhang Jingyong 
Published: July 2019

Purpose To compare hybrid and in vitro fenestration procedures for preserving the left subclavian artery in thoracic endovascular aortic repair (TEVAR) with unfavorable proximal landing zone. Methods Retrospective comparison of data from 49 consecutive patients who underwent left subclavian artery revascularization during TEVAR by either hybrid or fenestration approaches from January 2015 to March 2018. Procedural duration, and 30-day rates of procedural success, mortality and complications (endoleaks, cerebral infarction, spinal cord ischemia, left arm ischemic symptoms, and delirium) were compared. Results For hybrid procedure ( n = 32) vs. fenestration ( n = 17) groups, which were age and gender matched: procedural success rate was 100%, with significantly longer procedural duration (248.4 ± 40.9 vs. 60.6 ± 16.8 min; t = –22.653, P = 0.000) and similar 30-day complication rate (18.8% vs. 11.8%; χ2 = 0.397, P = 0.529). At 12.7 ± 9.3 months’ follow-up, there were no cases of death, spinal cord ischemia, or other complications in either group. Conclusions In this retrospective, single-center comparison, both hybrid and in vitro fenestration approaches for reconstructing the left subclavian artery in TEVAR with unfavorable proximal landing zone appeared safe and effective, with shorter procedural duration for fenestration. Larger studies with longer term follow-up are warranted.
Reaffirmation of the importance of follow-up ultrasound studies in patients with high D-dimers and clinical suspicion of vein thrombosis
Authors: Tung-Chen Y , Pizarro I , Rivera-Núñez A , Martínez-Virto A , Lorenzo-Hernández A , Sancho-Bueso T , Rodríguez-Dávila MA , Fernández-Capitán C , Villén-Villegas T 
Published: July 2019

Background Venous thromboembolism is a common disease seen in the emergency department and a cause of high morbidity and mortality, constituting a major health problem. Objectives To assess the potential benefit of follow-up ultrasound of patients who attended the emergency department with suspected superficial venous thrombosis or deep venous thrombosis and were found to have an initial negative whole-leg (or arm) ultrasound study. Methods This retrospective study included patients aged 18 years or older who were consecutively referred to a thrombosis clinic from the emergency department, with abnormal D-dimer test and moderate to high pre-test probability of deep venous thrombosis (Well's score ≥ 1), but a negative whole-leg (or arm) ultrasound. Demographic characteristics, symptom duration, laboratory and ultrasound data were recorded. At one-week follow-up, an experienced physician repeated ultrasound, and recorded the findings. Results From January 2017 to April 2018, 54 patients were evaluated. The mean age was 66.8 years (SD 15.0) and 63% were women. The average D-dimer was 2159.9 (SD 3772.0) ng/mL. Ultrasound abnormalities were found in 12 patients (22.2%; 95% confidence interval of 12.5 to 36.0%), with 4 patients having proximal deep venous thrombosis, distal deep venous thrombosis in 2 patients and superficial venous thrombosis in 6 patients. We did not find any significant differences in demographic characteristics, venous thromboembolism risk factors or laboratory parameters between patients with negative and positive follow-up ultrasound. Conclusions These preliminary findings suggest that a negative whole-leg (or arm) ultrasound in addition to an abnormal D-dimer in moderate to high deep venous thrombosis pretest probability patients, might be an insufficient diagnostic approach to exclude suspected deep venous thrombosis or superficial venous thrombosis. Confirmation of this higher than expected prevalence would support the need to repeat one-week ultrasound control in this population.
Therapeutic effect on experimental acute cerebral infarction is enhanced after nanoceria labeling of human umbilical cord mesenchymal stem cells
Authors: Zuo Lian , Feng Qishuai , Han Yingying , Chen Mengwei , Guo Mengruo , Liu Zhongmin , Cheng Yu , Li Gang 
Published: July 2019

Background: Therapeutic applications of stem cells, especially mesenchymal stem cells, were once regarded as a promising therapy for mitigating acute cerebral infarction. Unfortunately, all the stem cell clinical trials have been futile. A new stroke therapeutic strategy of combining stem cells with nanotechnology has recently gained significant attention. The objective of this study was to evaluate the application of cerium oxide nanoparticle (nanoceria)-labeled human umbilical cord mesenchymal stem cells (HucMSCs) for stroke therapy. Methods: In our study, cerium oxide nanoparticles were precovered with hyaluronic acid before labeling HucMSCs and the synergistic effects from both HucMSCs and cerium oxide nanoparticles were analyzed in in vivo and in vitro experiments Results: The nanoceria-labeled HucMSCs combined advantages from both sides, including the capacity for inflammatory modulation of HucMSCs and the antioxidant effects of nanoceria. Compared with either HucMSCs or nanoceria individually, nanoceria-labeled HucMSCs exerted significantly enhanced capacities after gaining combined antioxidant and anti-inflammatory effects. Conclusion: Our findings suggest a novel strategy with effective and well-tolerated applications of stem cells for acute cerebral infarction therapy after modification of cells with nanomaterials.
Fetal and infant growth patterns and left and right ventricular measures in childhood assessed by cardiac MRI
Authors: Toemen Liza , Gaillard Romy , Roest Arno A , van der Geest Rob J , Steegers Eric AP , van der Lugt Aad , Helbing Willem A , Jaddoe Vincent WV 
Published: July 2019

Objectives Early life is critical for cardiac development. We examined the associations of longitudinal fetal and childhood growth patterns with childhood right and left ventricular structures measured by cardiac magnetic resonance imaging. Methods In a population-based prospective cohort study among 2827 children, we measured growth at 20 and 30 weeks of pregnancy, at birth, 0.5, 1, 2, 6 and 10 years. At 10 years, we measured right ventricular end-diastolic volume, left ventricular end-diastolic volume, left ventricular mass and left ventricular mass-to-volume ratio by cardiac magnetic resonance imaging. Results Small size for gestational age at birth was associated with smaller right and left ventricular end-diastolic volume relative to current body surface area, but with larger left ventricular mass-to-volume ratio ( P < 0.05). Children in the upper 25% of right and left ventricular end-diastolic volume and left ventricular mass at age 10 years were larger at birth and became taller and leaner in childhood ( P < 0.05). In contrast, children in the lower 25% of right and left ventricular end-diastolic volume and left ventricular mass were smaller at birth and became shorter and heavier in childhood ( P < 0.05). Both fetal and childhood growth were independently of each other associated with childhood right and left ventricular end-diastolic volume and left ventricular mass. Conclusion Children who are larger at birth and grow taller and leaner in childhood have larger hearts relative to body surface area. Small size at birth children, who grow shorter and heavier in childhood, have relatively smaller hearts with larger left ventricular mass-to-volume ratio. Both fetal and childhood growth are important for the development of cardiac dimensions.
Content and Quality of Websites for Patients With Chronic Kidney Disease: An Environmental Scan
Authors: Smekal Michelle , Gil Sarah , Donald Maoliosa , Beanlands Heather , Straus Sharon , Herrington Gwen , Sparkes Dwight , Harwood Lori , Tong Allison , Grill Allan , Tu Karen , Waldvogel Blair , Large Chantel , Large Claire , Novak Marta , James Matthew , Elliott Meghan , Delgado Maria , Brimble Scott , Samuel Susan , Hemmelgarn Brenda R. 
Published: July 2019

Background: Although numerous websites for patients with chronic kidney disease (CKD) are available, little is known about their content and quality. Objective: To evaluate the quality of CKD websites, and the degree to which they align with information needs identified by patients with CKD. Methods: We identified websites by entering “chronic kidney disease” in 3 search engines: Google.com (with regional variants for Australia, Canada, the United Kingdom, and the United States), Bing.com, and Yahoo.com. We included the first 50 unique English-language sites from each search. We evaluated website content using a 30-point scale comprising 8 priority content domains identified by patients with CKD ( understanding CKD, diet, symptoms, medications, mental/physical health, finances, travel, and work/school). We used standardized tools to evaluate usability, reliability, and readability (DISCERN, HONcode, LIDA, Reading Ease, and Reading Grade Level). Two reviewers independently conducted the search, screen, and evaluation. Results: Of the 2093 websites identified, 115 were included. Overall, sites covered a mean (SD) of 29% (17.8) of the CKD content areas. The proportion of sites covering content related to understanding CKD, symptoms, and diet was highest (97%, 80%, and 72%, respectively). The proportion of sites covering travel, finances, and work/school content was lowest (22%, 12%, and 12%, respectively). The mean (SD) scores for DISCERN, LIDA and HONcode were 68% (14.6), 71% (14.4), and 75% (17.2), respectively, considered above average for usability and reliability. The mean (SD) Reading Grade Level was 10.6 (2.8) and Reading Ease was 49.8 (14.4), suggesting poor readability. Conclusions: Although many CKD web sites were of reasonable quality, their readability was poor. Furthermore, most sites covered less than 30% of the content patients identified as important for CKD self-management. These results will inform content gaps in internet-accessible information on CKD self-management that should be addressed by future eHealth web-based tools.