bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dietary differences between metabolically healthy overweight-obese and metabolically unhealthy overweight-obese adults
Authors: Jurado-Fasoli Lucas , De-la-O Alejandro , Castillo Manuel J. , Amaro-Gahete Francisco J. 
Published: August 2019

AbstractThe aim of the study is to determine the differences in dietary parameters (energy and nutrient intake, adherence to the Mediterranean diet and consumption of food groups) in metabolically healthy overweight-obese (MHOO)v. metabolically unhealthy overweight-obese (MUOO) middle-aged adults. A total of fifty-one middle-aged adults were classified as MHOO or MUOO. BMI and blood pressure were evaluated following the recommendations. HDL, TAG and blood glycaemia were measured in blood samples. Blood pressure was also assessed. Dietary factors were assessed through three 24-h recalls, a validated FFQ and the PREvención con DIeta MEDiterránea (PREDIMED) questionnaire. All variables were evaluated between September and October 2016 and 2017. Our results showed that MHOO individuals registered a higher fish consumption (P= 0·035) and higher compliance (lower consumption) in the commercial sweets and confectionery item of the PREDIMED questionnaire (P= 0·036). No differences were noted in other dietary factors including energy and nutrient intake, consumption of other food groups and in the PREDIMED total score. A near-significant trend toward significance was observed in nuts consumption, wine and fish items of the PREDIMED questionnaire. In conclusion, higher fish consumption and a higher compliance in the commercial sweets and confectionery item of the PREDIMED questionnaire were observed in MHOO middle-aged adults.
Programming effects of an early life diet containing large phospholipid-coated lipid globules are transient under continuous exposure to a high-fat diet
Authors: Ronda Onne A. H. O. , van de Heijning Bert J. M. , de Bruin Alain , Jurdzinski Angelika , Kuipers Folkert , Verkade Henkjan J. 
Published: August 2019

AbstractBreast-feeding is associated with a lower risk of developing obesity during childhood and adulthood compared with feeding infant milk formula (IMF). Previous studies have shown that an experimental IMF (eIMF; comprising Nuturis®) programmed mouse pups for a lower body weight and fat mass gain in adulthood when challenged with a high-fat diet (HFD) compared with a control IMF (cIMF). Nuturis has a lipid composition and structure more similar to breast milk. Here, the long-term effects were tested of a similar eIMF, but with an adapted lipid composition and a cIMF, on body weight, glucose homoeostasis, liver and adipose tissue. Nutrient composition was similar for the eIMF and cIMF; the lipid fractions comprised approximately 50 % milk fat. C57BL/6JOlaHsd mice were fed cIMF or eIMF from postnatal day (PN) 16–42 followed by an HFD until PN168. Feeding eIMF v. cIMF in early life resulted in a lower body weight (–9 %) and body fat deposition (–14 %) in adulthood (PN105). The effect appeared transient, as from PN126 onwards, after 12 weeks’ HFD, eIMF-fed mice caught up on controls and body and fat weights became comparable between groups. Glucose and energy metabolism were similar between groups. At dissection (PN168), eIMF-fed mice showed larger (+27 %) epididymal fat depots and a lower (–26 %) liver weight without clear morphological aberrations. Our data suggest the size and coating but not the lipid composition of IMF fat globules underlie the programming effect observed. Prolonged exposure to an HFD challenge partly overrules the programming effect of early diet.
‘Urgent suspicion of cancer’ referrals to a head and neck clinic – what do patients expect?
Authors: Montgomery J , Douglas C M , Begbie F , Hitchings A , MacKenzie K 
Published: August 2019

AbstractBackgroundPublic awareness of ‘red flag’ symptoms for head and neck cancer is low. There is a lack of evidence regarding patient concerns and expectations in consultations for cancer assessment.MethodThis prospective questionnaire study examined the symptoms, concerns and expectations of 250 consecutive patients attending an ‘urgent suspicion of cancer’ clinic at a tertiary referral centre.ResultsThe patients’ most frequent responses regarding their concerns were ‘no concerns’ (n = 72, 29 per cent); ‘all symptoms’ were a cause for concern (n = 65, 26 per cent) and ‘neck lump’ was a symptom causing concern (n = 37, 17 per cent). The expectations of patients attending clinic were that they would find out what was wrong with them, followed by having no expectations at all. Overall patient knowledge of red flag symptoms was lacking and their expectations were low.ConclusionPatients with non-cancer symptoms are frequently referred with suspected cancer. Patients with red flag symptoms are not aware of their significance and they have low expectations of healthcare.
Maternal depression and inflammation during pregnancy
Authors: Lahti-Pulkkinen Marius , Girchenko Polina , Robinson Rachel , Lehto Soili M. , Toffol Elena , Heinonen Kati , Reynolds Rebecca M. , Kajantie Eero , Laivuori Hannele , Villa Pia M. , Hämäläinen Esa , Lahti Jari , Räikkönen Katri 
Published: August 2019

BackgroundMaternal depression during pregnancy increases the risk for adverse developmental outcomes in children. However, the underpinning biological mechanisms remain unknown. We tested whether depression was associated with levels of and change in the inflammatory state during pregnancy, if early pregnancy overweight/obesity or diabetes/hypertensive pregnancy disorders accounted for/mediated these effects, and if depression added to the inflammation that typically accompanies these conditions.MethodsWe analyzed plasma high-sensitivity C-reactive protein (hsCRP) and glycoprotein acetyls at three consecutive stages during pregnancy, derived history of depression diagnoses before pregnancy from Care Register for Healthcare (HILMO) (N = 375) and self-reports (N = 347) and depressive symptoms during pregnancy using the Center for Epidemiological Studies Depression Scale completed concurrently to blood samplings (N = 295). Data on early pregnancy body mass index (BMI) and diabetes/hypertensive pregnancy disorders came from medical records.ResultsHigher overall hsCRP levels, but not change, during pregnancy were predicted by history of depression diagnosis before pregnancy [HILMO: mean difference (MD) = 0.69 standard deviation (s.d.) units; 95% confidence interval (CI) 0.26–1.11, self-report: MD = 0.56 s.d.; 95% CI 0.17–0.94] and higher depressive symptoms during pregnancy (0.06 s.d. per s.d. increase; 95% CI 0.00–0.13). History of depression diagnosis before pregnancy also predicted higher overall glycoprotein acetyls (HILMO: MD = 0.52 s.d.; 95% CI 0.12–0.93). These associations were not explained by diabetes/hypertensive disorders, but were accounted for and mediated by early pregnancy BMI. Furthermore, in obese women, overall hsCRP levels increased as depressive symptoms during pregnancy increased (p = 0.006 for interaction).ConclusionsDepression is associated with a proinflammatory state during pregnancy. These associations are mediated by early pregnancy BMI, and depressive symptoms during pregnancy aggravate the inflammation related to obesity.
Is the God of Anselm unloving? A response to Eleonore Stump
Authors: STEPHAN HAYDEN C. 
Published: August 2019

AbstractIn her recent book Atonement, Eleonore Stump objects to the Anselmian theory of atonement, claiming it is not consistent with God's love. I argue that her objection mischaracterizes Anselmian theories. First, Stump equivocates on the concept of forgiveness, conflating personal forgiveness with divine pardon, and second, Stump misrepresents the God of Anselm as unwilling to reconcile with sinners prior to receiving satisfaction. I suggest that Stump's real objection should be to the Anselmian view of divine justice as retributive, not to his conception of divine love. I suggest a model of an all-loving God acting as a retributive judge.
How do collective student behavior and other classroom contextual factors relate to teachers’ implementation of an evidence-based intervention? A multilevel structural equation model
Authors: Musci Rashelle J. , Pas Elise T. , Bettencourt Amie F. , Masyn Katherine E. , Ialongo Nicholas S. , Bradshaw Catherine P. 
Published: August 2019

AbstractBuilding on prior work regarding the potential for peer contagion or deviance training in group delivered interventions (Dishion & Dodge, 2005, 2006; Dodge, Dishion, & Lansford, 2006), we leveraged data from a randomized trial, testing the integration of two preventive interventions (Promoting Alternative THinking Strategies and PAX Good Behavior Game), to explore the extent to which classroom contextual factors served as either a barrier to or a motivator for teachers to implement the evidence-based PAX Good Behavior Game with high frequency or dosage. We included students’ baseline levels of behavior, measured with regard to both positive (i.e., engagement and social emotional skills) and negative (i.e., hyperactive and aggressive-disruptive) behaviors. Data were collected from 204 teachers in 18 urban elementary schools. A series of multilevel structural equation models were fit to the data. The analyses indicated that classrooms with higher classroom levels of aggressive behavior, on average, at baseline had teachers with lower implementation dosage (i.e., played fewer games) across the school year. In addition, teachers who reported higher baseline levels of emotional exhaustion, regardless of student behavior, also reported lower implementation dosage. Taken together, the results indicated that negative, but not positive, contextual factors at baseline were related to lower implementation dosage; this, in turn, suggests that negative contextual factors may serve as a barrier, rather than a motivator, of teachers’ implementation dosage of classroom-based preventive interventions.
The Case for Non-Binary Gender Questions in Surveys
Authors: Medeiros Mike , Forest Benjamin , Öhberg Patrik 
Published: August 2019

ABSTRACTLGBTQ activists and academics advocate the use of non-binary gender categories to include individuals who identify as neither rigidly male nor rigidly female to reflect the increasing number of people who do not place themselves in these two conventional classes. Although some general-population surveys have begun using non-binary gender questions, research has not examined the consequences of using (or not) a question with non-binary gender categories in surveys and censuses. Our study addresses this gap using a survey experiment in which respondents in the United States, Canada, and Sweden randomly received a binary or a non-binary gender question. We find no evidence of negative reactions to the non-binary question. Moreover, when there is a statistical difference, the reactions are positive. We thus conclude that general-population surveys could use a non-binary question without facing significant adverse reactions from respondents.
Greater adherence to a Mediterranean-like diet is associated with later breast development and menarche in peripubertal girls
Authors: Szamreta Elizabeth A , Qin Bo , Rivera-Núñez Zorimar , Parekh Niyati , Barrett Emily S , Ferrante Jeanne , Lin Yong , Bandera Elisa V 
Published: August 2019

AbstractObjective:To examine adherence to a Mediterranean-like diet at age 9–10 years in relation to onset of breast development (thelarche) and first menstruation (menarche).Design:We evaluated the associations of adherence to a Mediterranean-like diet (measured by an adapted Mediterranean-like Diet Score, range 0–9) with thelarche at baseline, age at thelarche and time to menarche. Data were collected at baseline during a clinic visit, complemented with a mailed questionnaire and three 24 hour telephone dietary recalls, followed by annual follow-up questionnaires. Multivariable Poisson regression, linear regression and Cox proportional hazards regression were used to evaluate timing of pubertal development in relation to diet adherence.Setting:New Jersey, USA.Participants:Girls aged 9 or 10 years at baseline (2006–2014,n 202).Results:High Mediterranean-like diet adherence (score 6–9) was associated with a lower prevalence of thelarche at baseline compared with low adherence (score 0–3; prevalence ratio = 0·65, 95 % CI 0·48, 0·90). This may have been driven by consumption of fish and non-fat/low-fat dairy. Our models also suggested a later age at thelarche with higher Mediterranean-like diet adherence. Girls with higher Mediterranean-like diet adherence had significantly longer time to menarche (hazard ratio = 0·45, 95 % CI 0·28, 0·71 for highv. low adherence). Further analysis suggested this may have been driven by vegetable and non-fat/low-fat dairy consumption.Conclusions:Consuming a Mediterranean-like diet may be associated with older age at thelarche and menarche. Further research is necessary to confirm our findings in other US paediatric populations and elucidate the mechanism through which Mediterranean-like diet may influence puberty timing.
Use of hypnosis for the placement of a midline catheter in a patient at the end of life
Authors: Ibañez del Prado Celia , Cruzado Juan Antonio , González Ordi Héctor , Capilla Ramírez Pilar 
Published: August 2019

AbstractObjectiveThe case of a non-oncological patient at the end of his life, admitted to a Palliative Care Unit (PCU), is presented. After a failed attempt to place a central venous catheter (CVC) and another placement of a peripherally inserted central catheter (PICC), the patient exhibited high anxiety regarding a midline catheter (MC) and refused its placement, even though this was necessary for the administration of intravenous drugs to control dyspnea and other complex symptoms that he presented.MethodAn intervention through clinical hypnosis for successful MC placement and symptom control is described.ResultThrough clinical hypnosis and interdisciplinary teamwork, it was possible to place a MC, necessary for symptomatic control of a complex patient.Significance of resultThis case exemplifies hypnosis as a simple procedure that is easy to apply, accepted by the patient, and effective in the implementation of invasive procedures and symptom control in PCUs.
The effect of omega-3 and vitamin E on oxidative stress and inflammation: Systematic review and meta-analysis of randomized controlled trials
Authors: Moosavian Seyedeh Parisa , Arab Arman , Mehrabani Sanaz , Moradi Sajjad , Nasirian Maryam 
Published: August 2019

Abstract. Background: Several studies have investigated the effect of omega-3 fatty acids and vitamin E on oxidative stress and inflammation, but their findings are inconsistent. The aim of this meta-analysis is to elucidate the overall effects of co-supplementation with omega-3 fatty acids and vitamin E on oxidative stress and inflammation. Methods: We searched titles, abstracts, and keywords of relevant articles indexed in PubMed, ISI, Scopus, and Google Scholar databases up to December 2018 to identify eligible RCT studies. Random effects model was used to estimate the pooled effect of co-supplementation with omega-3 fatty acids and vitamin E on oxidative stress and inflammation. Results: Overall, 7 RCTs with 504 participants were included in this meta-analysis. We found that co-supplementation with omega-3 fatty acids and vitamin E decreased hs-CRP (weighed mean difference (WMD) = −2.15 mg/L; 95% CI: −3.40, −0.91 mg/L; P < 0.001) concentrations and increased total antioxidant capacity (TAC) (WMD = 92.87 mmol/L; 95% CI: 31.97, 153.77 mmol/L; P = 0.03), and nitric oxide levels (NO) (WMD: 6.95 μmol/L; 95% CI: 3.86, 10.04, P < 0.001) compared with control group. Omega-3 fatty acids and vitamin E had no significant effect on malondialdehyde (MDA) (WMD: 1.54 mmol/L; 95% CI: −1.29, 4.36; P = 0.196), and glutathione (GSH) (WMD: 20.87 mmol/L; 95% CI: −20.04, 61.6, P = 0.31) levels. Conclusion: The present meta-analysis found that omega-3 fatty acids and vitamin E co-supplementation significantly decreased hs-CRP and increased NO and TAC, although it had no significant effect on MDA and GSH.
Direct Inversion for Three‐Dimensional Shear Wave Speed Azimuthal Anisotropy Based on Surface Wave Ray Tracing: Methodology and Application to Yunnan, Southwest China
Authors: Liu Chuanming , Yao Huajian , Yang Hsin‐Ying , Shen Weisen , Fang Hongjian , Hu Shaoqian , Qiao Lei 
Published: August 2019

AbstractAzimuthal anisotropy retrieved from surface waves is important for constraining depth‐varying deformation patterns in the crust and upper mantle. We present a direct inversion technique for the three‐dimensional shear wave speed azimuthal anisotropy based on mixed‐path surface wave traveltime data. This new method includes two steps: (1) inversion for the 3‐D isotropic Vsv model directly from Rayleigh wave traveltimes and (2) joint inversion for both 3‐D Vsv azimuthal anisotropy and additional 3‐D isotropic Vsv perturbation. The joint inversion can significantly mitigate the trade‐off between strong heterogeneity and anisotropy. With frequency‐dependent ray tracing based on 2‐D isotropic phase speed maps, the new method takes into account the ray‐bending effect on surface wave propagation. We apply the new method to a regional array in Yunnan, southwestern China. Using Rayleigh wave phase velocity dispersion data in the period band of 5–40 s extracted from ambient noise interferometry, we obtain a 3‐D model of shear wave speed and azimuthal anisotropy in the crust and uppermost mantle in Yunnan. This model reveals that two midcrust low‐velocity zones are possible weak channels, and the azimuthal anisotropy at a depth of 5 to 30 km is mainly controlled by nearby strike‐slip faults, some of which also approximately coincide with the lateral boundaries of the crustal low‐velocity zones. Approximately south of 26°N, the upper crustal azimuthal anisotropy from our model is significantly different from the upper mantle anisotropy inferred by shear wave splitting, indicating different deformation styles between the crust and upper mantle in southern Yunnan.
Comparison of Ground‐Based Ionospheric Scintillation Observations With In Situ Electron Density Variations as Measured by the Swarm Satellites
Authors: Olwendo J. , Cilliers P. J. , Ming Ou 
Published: August 2019

AbstractIonospheric scintillation is known to be associated with irregularities in electron density, which manifests as rapid fluctuations in the amplitude and phase of radio signals traversing the ionosphere. The scintillations caused by irregularity structures in the ionosphere can be directly measured using ground‐based GPS scintillation measurement receivers. In this work we have used in situ measurements of electron density by means of the Langmuir probe on the Swarm satellites to derive an index called the rate of density index (RODI). Using a ground‐based International Global Navigation Satellite Systems Service receivers and one dedicated scintillation measurement receiver, we have examined if we can identify ionospheric scintillation events that are correlated with space‐based electron density variations characterized by the RODI for cases when the Swarm satellites orbital tracks traverse coincidental locations to the ground‐based station. The selected Swarm B passes over Africa have been limited to the longitudes within ±7° of longitude relative to the position of a dedicated scintillation receiver located at Pwani, Kenya (Geo. Lon: 39.78°E, Geo. Lat: 3.24°S). Our results show that RODI could be a useful index for detecting irregularities associated with scintillation events that can also be observed from the ground. There is a similarity in RODI fluctuations and ground‐based irregularity measures based on rate of total electron content index with an asymmetry in irregularity activity across African region. There is stronger irregularity activity and high background nighttimes electron density on the western side of Africa than on the eastern side. This work shows the potential of using space‐based in situ measurement for scintillation detection and mitigation for operational purposes particularly for regions where terrestrial scintillation measurement are not possible like over oceans and deserts.
Surface and Sub‐surface Ocean Response to Tropical Cyclone Phailin: Role of Pre‐existing Oceanic Features
Authors: Jyothi Lingala , Joseph Sudheer , P Suneetha 
Published: August 2019

AbstractThe upper oceanic thermal response induced by Tropical Cyclone Phailin (9–14 October 2013) under the influence of East India Coastal Current (EICC) and a cyclonic eddy is investigated and contrasted with the response from open ocean region using a high‐resolution HYbrid Coordinate Ocean Model simulation. There is significant cooling (7° C) inside the cold core eddy and negligible cooling (0.5° C) within the EICC region characterized by the shallow and deeper thermocline, respectively. Our analysis of mixed layer heat budget terms showed that the horizontal advection plays a significant role in determining the temperature tendency for the location within the EICC, in contrary to the general dominance of vertical processes as reported in previous studies during the cyclone period. The analysis for the locations inside eddy and open ocean concurs with the previous studies showing the dominance of vertical processes toward the temperature tendency. Further, near the coast, the surface cooling is minimal compared to the subsurface cooling, dominantly seen between 50‐ and 100‐m depth. This disparity indicates that the factors responsible for the surface temperature anomalies are different from those of subsurface. Our analysis of thermal signatures after the passage of cyclone showed that the EICC and cyclonic eddy contribute to the faster advection of cold wake and recovery of sea surface temperature to the prestorm state.
Regional Moisture Budget and Land‐Atmosphere Coupling Over the U.S. Southern Great Plains Inferred From the ARM Long‐Term Observations
Authors: Tao Cheng , Zhang Yunyan , Tang Shuaiqi , Tang Qi , Ma Hsi‐Yen , Xie Shaocheng , Zhang Minghua 
Published: August 2019

AbstractTen‐year warm‐season (May–August) observations at the Atmospheric Radiation Measurement (ARM) Southern Great Plains (SGP) site are used to examine the large‐scale atmospheric moisture budget and the strength of land‐atmosphere coupling. Atmospheric moisture budget components, computed from the ARM variational analysis data, are compared between different wet/dry scenarios and convection regimes. Consistent with previous studies, large‐scale moisture flux convergence dominates the SGP regional moisture budget on the daily time scale, but surface evaporation does play a more prominent role on late‐afternoon deep convection days. Moreover, the relationship between moisture flux convergence and precipitation increases significantly from dry year to wet years. The land‐atmosphere coupling strength is quantified for local convective events within the “Local L‐A Coupling Process Chain” (Santanello et al., 2018, https://doi.org/10.1175/BAMS‐D‐17‐0001.1). The impact of land surface on the evolution of planetary boundary layer is highly dependent on the vegetation leaf area index. A significantly larger surface sensible heat flux is found over the SGP forest region in midsummer, which is accompanied by a much higher planetary boundary layer development and a large increase in shallow cumulus cloud fraction. The significant relationship between afternoon precipitation and surface turbulent flux only exists in the northeast part of the ARM SGP site, which is mainly covered by grassland/pasture.