bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of stress on failure behaviour of shallow-marine muds from the northern Gulf of Mexico
Authors: Dugan Brandon , Zhao Xin 
Published: April 2018

Abstract
Direct simple shear experiments on mud samples from 0 to 15 mbsf (metres below seafloor) in the Ursa Basin (northern Gulf of Mexico) document that stress level impacts shear strength and pore pressure during failure. As burial depth increased (from 7.35 to 13.28 mbsf), cohesion decreased (from 12.3 to 6.5 kPa) and the internal friction angle increased (from 18° to 21°). For a specimen from 11.75 mbsf, an increase in maximum consolidation stress (from 45 to 179 kPa) resulted in an increase in the shear-induced pore pressure (from 29 to 150 kPa); however, the normalized peak shear stress decreased (from 0.37 to 0.25). Our results document that consolidation at shallow depths induces a positive feedback on pore-pressure genesis. For resedimented samples, which lack a stress history, cohesion was 3.6 kPa and the internal friction angle was 24°. As the maximum consolidation stress increased (from 40 to 254 kPa) on resedimented samples, the shear-induced pore pressure increased (from 22 to 203 kPa), whereas the normalized peak shear stress decreased (from 0.32 to 0.25). Our experiments showed that resedimented samples have similar strength and failure behaviour to intact samples. By constraining pore pressure, strength and initial stress state, we gain a better insight into slope-failure dynamics. Therefore, our experiments provide constraints on strength and shear-induced pore pressure at the onset of shallow failure that could be included in slope-failure and hazard models.
Delays in the Air or Ground Transfer of Patients for Endovascular Thrombectomy
Authors: Regenhardt Robert W. , Mecca Adam P. , Flavin Stephanie A. , Boulouis Gregoire , Lauer Arne , Zachrison Kori Sauser , Boomhower James , Patel Aman B. , Hirsch Joshua A. , Schwamm Lee H. , Leslie-Mazwi Thabele M. 
Published: April 2018

Background and Purpose—
For suspected large vessel occlusion patients efficient transfer to centers that provide endovascular therapy (ET) is critical to maximizing treatment opportunity. Our objective was to examine associations between transfer time, modes of transfer, ET, and outcomes within a hub-and-spoke telestroke network.

Methods—
Patients with ischemic stroke were included if transferred to a single hub hospital between January 2011 and October 2015 with National Institutes of Health Stroke Scale>6, onset<12 hours from hub arrival with complete clinical, imaging, and transfer data. Transfer time was the interval between initiation of telestroke consult and arrival at the hub. Algorithms were created for ideal transfer times; ideal time was subtracted from actual time to calculate delay. We examined bivariate relationships between transfer time and several clinical outcomes and used multivariable regression modeling to explore possible predictors of delay.

Results—

Of 234 patients that met inclusion criteria, 51% were transferred by ambulance and 49% by helicopter; 27% underwent ET (36% achieved modified Rankin Scale score of 0–2 at 90 days). Median actual transfer time was 132 minutes (interquartile range, 103–165), compared with median ideal transfer time at 102 minutes (interquartile range, 96–123). Longer transfer time was associated with decreased likelihood of undergoing ET (odds ratio, 0.990;
P
=0.003). Nocturnal transfer (18:00 to 06:00 hours) was associated with significantly longer delay (β=20.5;
P
<0.0005), whereas intravenous tissue-type plasminogen activator (tPA) delivery at spoke hospital was not. The median delay for nocturnal transfer was 31 minutes (interquartile range, 11–51), compared with daytime at 14 minutes (interquartile range, −9 to 36).

Conclusions—
Within a large telestroke network, there was an association between longer transfer time and decreased likelihood of undergoing ET. Nocturnal transfers were associated with a substantial delay relative to daytime transfers. In contrast, delivery of tPA was not associated with delays, underscoring the impact of effective protocols at spoke hospitals. More efficient transfer may enable higher ET treatment rates. Metrics and protocols for transfer, especially at night, may improve transfer times.
Brain-to-Brain Synchrony and Learning Outcomes Vary by Student–Teacher Dynamics: Evidence from a Real-world Classroom Electroencephalography Study
Authors: Bevilacqua Dana , Davidesco Ido , Wan Lu , Chaloner Kim , Rowland Jess , Ding Mingzhou , Poeppel David , Dikker Suzanne 
Published: April 2018

AbstractHow does the human brain support real-world learning? We used wireless electroencephalography to collect neurophysiological data from a group of 12 senior high school students and their teacher during regular biology lessons. Six scheduled classes over the course of the semester were organized such that class materials were presented using different teaching styles (videos and lectures), and students completed a multiple-choice quiz after each class to measure their retention of that lesson's content. Both students' brain-to-brain synchrony and their content retention were higher for videos than lectures across the six classes. Brain-to-brain synchrony between the teacher and students varied as a function of student engagement as well as teacher likeability: Students who reported greater social closeness to the teacher showed higher brain-to-brain synchrony with the teacher, but this was only the case for lectures—that is, when the teacher is an integral part of the content presentation. Furthermore, students' retention of the class content correlated with student–teacher closeness, but not with brain-to-brain synchrony. These findings expand on existing social neuroscience research by showing that social factors such as perceived closeness are reflected in brain-to-brain synchrony in real-world group settings and can predict cognitive outcomes such as students' academic performance.
Early Warnings of Severe Convection Using the ECMWF Extreme Forecast Index
Authors: Tsonevsky Ivan , Doswell Charles A. , Brooks Harold E. 
Published: April 2018

Abstract
ECMWF provides the ensemble-based extreme forecast index (EFI) and shift of tails (SOT) products to facilitate forecasting severe weather in the medium range. Exploiting the ingredients-based method of forecasting deep moist convection, two parameters, convective available potential energy (CAPE) and a composite CAPE–shear parameter, have been recently added to the EFI/SOT, targeting severe convective weather. Verification results based on the area under the relative operating characteristic curve (ROCA) show high skill of both EFIs at discriminating between severe and nonsevere convection in the medium range over Europe and the United States. In the first 7 days of the forecast ROCA values show significant skill, staying well above the no-skill threshold of 0.5. Two case studies are presented to give some practical considerations and discuss certain limitations of the EFI/SOT forecasts and how they could be overcome. In particular, both convective EFI/SOT products are good at providing guidance for where and when severe convection is possible if there is sufficient lift for convective initiation. Probability of precipitation is suggested as a suitable ensemble product for assessing whether convection is likely to be initiated. The model climate should also be considered when determining whether severe convection is possible; EFI and SOT values are related to the climatological frequency of occurrence of deep, moist convection over a given place and time of year.
Students’ adherence to dietary recommendations and their food consumption habits
Authors: Stroebele-Benschop Nanette , Dieze Anastasia , Hilzendegen Carolin 
Published: April 2018

Background: Habitual behavior rather than intention has been linked to food intake patterns. Aim: The purpose of this study was to examine the adherence to dietary recommendations in university students and to analyze whether habit strength predicts food consumption. Methods: A student sample of the University (University of Hohenheim) was recruited ( n = 103; age range 18–30 years). Habit strength for consuming the food groups fruits, vegetables, whole grains, milk, meat, convenience foods, sugary and savory snacks, water and sugar-sweetened beverages was measured using a questionnaire. Food intake was measured via a self-administered online food frequency survey two weeks later, which was then compared to dietary recommendations. For associations of habit strength and consumption, Kendall’s Tau-c correlation coefficient was calculated. Results: The majority of students failed to meet the recommendations for all food groups except meat, eggs, oil, fat, and water. Only 4.2% of men (15.4% of women) consumed the recommended daily amount of vegetables. Fruit recommendations were met by 20.8% of men (43.6% of women). Habit strength was significantly associated with the consumption of most food groups. Conclusion: Adhering to dietary recommendations appeared to be difficult. Educational efforts should be undertaken to improve students’ diet considering habit strength as an important determinant of food intake.
The epidemiology of 5-methoxy-N, N-dimethyltryptamine (5-MeO-DMT) use: Benefits, consequences, patterns of use, subjective effects, and reasons for consumption
Authors: Davis Alan K , Barsuglia Joseph P , Lancelotta Rafael , Grant Robert M , Renn Elise 
Published: April 2018

Background/aim: 5-Methoxy- N,N-dimethyltryptamine (5-MeO-DMT) is a psychoactive compound found in several plants and in high concentrations in Bufo alvarius toad venom. Synthetic, toad, and plant-sourced 5-MeO-DMT are used for spiritual and recreational purposes and may have psychotherapeutic effects. However, the use of 5-MeO-DMT is not well understood. Therefore, we examined patterns of use, motivations for consumption, subjective effects, and potential benefits and consequences associated with 5-MeO-DMT use. Methods: Using internet-based advertisements, 515 respondents ( Mage=35.4. SD=11.7; male=79%; White/Caucasian=86%; United States resident=42%) completed a web-based survey. Results: Most respondents consumed 5-MeO-DMT infrequently (<once/year), for spiritual exploration, and had used less than four times in their lifetime. The majority (average of 90%) reported moderate-to-strong mystical-type experiences ( Mintensity=3.64, SD=1.11; range 0–5; e.g., ineffability, timelessness, awe/amazement, experience of pure being/awareness), and relatively fewer (average of 37%) experienced very slight challenging experiences ( Mintensity=0.95, SD=0.91; range 0–5; e.g., anxiousness, fear). Less than half (39%) reported repeated consumption during the same session, and very few reported drug craving/desire (8%), or legal (1%), medical (1%), or psychiatric (1%) problems related to use. Furthermore, of those who reported being diagnosed with psychiatric disorders, the majority reported improvements in symptoms following 5-MeO-DMT use, including improvements related to post-traumatic stress disorder (79%), depression (77%), anxiety (69%), and alcoholism (66%) or drug use disorder (60%). Conclusion: Findings suggest that 5-MeO-DMT is used infrequently, predominantly for spiritual exploration, has low potential for addiction, and might have psychotherapeutic effects. Future research should examine the safety and pharmacokinetics of 5-MeO-DMT administration in humans using rigorous experimental designs.
Approved and Off-Label Use of Prescribed Psychotropic Medications among Federal Canadian Inmates
Authors: Brown Gregory P. , Stewart Lynn A. , Rabinowitz Terry , Boudreau Harold , Wright Angela J. 
Published: April 2018

Objective: To examine psychotropic medication prescription practices in federal Canadian penitentiaries. Method: 468 files were drawn from a purposive sample of thirteen Canadian federal institutions representing the five regions, different security levels, and male and female designated facilities. Information on the names of all psychotropic medications prescribed, indications for use, dosage, frequency, and route of administration was retrieved. Designation of approved or off-label use of medications was determined by consulting: (1) the Health Canada (2016) Drug Product Database, (2) the Canadian Compendium of Pharmaceuticals and Specialties 2016, and (3) the American Hospital Formulary Service Drug Information 2016. Prescription rates were examined by gender, Indigenous ancestry, drug class, institutional infractions, and current offence. Results: 36.2% of prescriptions for psychotropic medication were coded as ‘off-label’. Anxiolytic/hypnotics drugs were the psychotropic drugs most commonly used for off-label purposes. There were no differences in the prevalence of approved versus off-label prescriptions based on Indigenous ancestry or gender, and no pattern of elevated off-label prescription practices for offenders involved in institutional misconducts or those sentenced for the most serious crimes. Conclusions: The rates of prescribing ‘off-label’ psychotropic medication are not elevated relative to other correctional settings or to rates cited in Canadian surveys conducted in the community.
Forms of Inter-party Cooperation: Electoral Coalitions and Party Mergers
Authors: Ibenskas Raimondas , Bolleyer Nicole 
Published: April 2018

This article is part of the special cluster titled Parties and Democratic Linkage in Post-Communist Europe, guest edited by Lori Thorlakson, and will be published in the August 2018 issue of EEPS Various forms of inter-party cooperation have important effects on party system fragmentation and stability in young democracies. However, the conceptualisation and measurement of these forms of inter-party cooperation and the examination of their consequences on party system development remain limited in the literature on parties and party systems. This research addresses this gap in the scholarship in three ways. First, we present the analytical scheme of different types of party cooperation. We argue that the forms of inter-party cooperation vary on two dimensions. The first dimension refers to their structural basis: the stability of the cooperation as captured by whether it is rule-based or, in other words, underpinned by shared rules that are mutually accepted. The second dimension refers to their scope: the number of functional areas of party life subject to cooperation. The two dimensions lead us to four basic forms of inter-party cooperation: (1) non-rule-based, functionally restricted coalitions; (2) rule-based, functionally restricted coalitions; (3) non-rule-based organization-wide mergers; and (4) rule-based organization-wide mergers. Second, we develop theoretical expectations on the frequency of these forms of inter-party cooperation in Central and Eastern Europe. Third, to test these expectations, we present empirical evidence on the number of electoral coalitions and mergers in the first six electoral periods in 10 countries in the region. The results of the analyses support our expectations: non-rule-based organization-wide mergers are rare. The other three forms of party cooperation (non-rule-based coalitions; rule-based coalitions; rule-based mergers) are fairly common in most countries in the region, although less so in the more recent electoral periods.
Distal ulnar fracture nonunion management: An uncommon case report
Authors: Lo Chi Kin , Kam Wing Lok 
Published: April 2018

Introduction:Isolated distal ulnar fracture is an uncommon injury. Only a few case series that look into the management of ulnar fracture nonunion have been reported in the literature.Case presentation:A middle‐aged manual worker presented to us for isolated fracture of his left distal ulna. He received open reduction and fixation of the distal ulnar fracture using distal ulna locking plate. It was complicated with nonunion and he complained of persistent wrist pain. This distal ulnar fracture nonunion was finally treated by Sauve‐Kapandji procedure with good functional outcome.Discussion:Displaced distal ulnar fracture should be reduced anatomically with rigid fixation to prevent disruption of the distal radioulnar joint. Fracture nonunion was traditionally managed with revision osteosynthesis and bone grafting. It is, however, technically difficult at the distal ulnar region because of the poor bone stock and lack of soft tissue coverage.Conclusion:We have demonstrated that the Sauvé‐Kapandji procedure is a good treatment alternative for distal ulnar fracture nonunion.
Understanding feline emotions: … and their role in problem behaviours
Authors: Heath Sarah 
Published: April 2018

Practical relevance: Despite its importance, emotional health is a subject that is sadly neglected in the context of companion animals. Understanding emotions is at the heart of veterinary behavioural medicine and is key to preventing, managing and treating reported behavioural problems in domestic cats. Clinical challenges: On a daily basis, veterinary practices are presented with the physical health impact of emotional health and with emotionally motivated behaviours that are undesirable to owners and/or detrimental to the cat. Emotional health is of equal importance to physical health and lies at the very core of veterinary medicine. Clinically, the emotional motivation for a behaviour must be identified before an assessment is made of whether the motivation is contextually appropriate and whether the cat’s response is justified and normal, or abnormal in the circumstances. Evidence base: The majority of referenced evidence for our understanding of emotional motivations in mammals has come from the human field, but recently there has been increasing interest in the emotional health of non-human animals and a resulting growth in research. This review draws on the published literature and the author’s personal experience to explore how emotions can influence feline behaviours. Global importance: Understanding the importance of emotional health is a major factor in ensuring positive welfare for cats, wherever they are kept as companion animals. It impacts on their physical health and their quality of life, and also on the relationship between cat and owner.
Regional Anesthesia for Arteriovenous Fistula Surgery May Reduce Hospital Length of Stay and Reoperation Rates
Authors: Cole Naida M. , Vlassakov Kamen , Brovman Ethan Y. , Heydarpour Mahyar , Urman Richard D. 
Published: April 2018

Background and Objectives: Regional anesthesia has been proposed as the preferred mode of anesthesia for arteriovenous fistula surgery due to its associated vasodilatory effects and fistula patency rates. We analyzed patient outcomes after arteriovenous fistula surgery for their association with the type of anesthesia received. Methods: The National Surgical Quality Improvement Project database was accessed to identify a cohort of 3199 patients undergoing arteriovenous fistula surgery from 2007 to 2015. Multiple regression models were used to examine the association of anesthesia with 12 postoperative outcomes. Additional multivariate logistic regression was performed to assess significant independent variables predictive of anesthesia choice. Results: Patients who received regional anesthesia had the shortest postoperative length of stay (0.67 [standard deviation: 2.0] days) compared to monitored anesthesia care/intravenous (IV) sedation (0.77 [1.8] days) and general anesthesia (1.44 [2.8] days). Administration of regional anesthesia was associated with a shorter length of stay compared to general anesthesia (odds ratio [OR]: 0.55, P = .001). Patients who received monitored anesthesia care/IV sedation had a lower risk of reoperation compared to general anesthesia (OR: 0.65, P = .012) but not compared to regional anesthesia (OR: 0.89, P = .759). Anesthesia type had no significant effects on other measured postoperative complications. Predictors of the type of anesthesia were age and surgical procedure as defined by Current Procedural Terminology code ( P < .001). Conclusions: Use of regional anesthesia is associated with a shorter postoperative length of stay after arteriovenous fistula surgery and lower risk of reoperation compared to general anesthesia or monitored anesthesia care/IV sedation. Regional anesthesia may be an excellent choice for arteriovenous fistula surgery to reduce postoperative length of stay and risk of reoperation.
Procalcitonin as a postoperative marker in the follow-up of patients affected by medullary thyroid carcinoma
Authors: Trimboli Pierpaolo , Lauretta Rosa , Barnabei Agnese , Valabrega Stefano , Romanelli Francesco , Giovanella Luca , Appetecchia Marialuisa 
Published: April 2018

Aim: Due to the limits of calcitonin, other markers are warranted to better manage medullary thyroid carcinoma patients, and procalcitonin has been reported as promising. Here we aimed to evaluate procalcitonin as a marker of medullary thyroid carcinoma in the post-treatment follow-up. Methods: Medullary thyroid carcinoma patients previously treated by thyroidectomy were enrolled. After complete imaging work-up (i.e. ultrasonography, computed tomography, magnetic resonance and 18FDG-PET-CT) we identified patients with structural recurrent/persistent medullary thyroid carcinoma (active medullary thyroid carcinoma) and subjects with no evidence of disease. Then, both calcitonin and procalcitonin were measured and their performance analyzed. Results: The final series included 55 medullary thyroid carcinoma patients treated and followed-up for about five years. Of these, 43 were assessed as no evidence of disease, and 12 as active medullary thyroid carcinoma. The median value of procalcitonin was significantly higher ( P < 0.0001) in active medullary thyroid carcinoma patients (3.10 ng/mL) than in those with no evidence of disease (0.10 ng/mL). Also, calcitonin levels of active medullary thyroid carcinoma (96.7 pg/mL) were significantly ( P < 0.0001) higher than that of no evidence of disease (2.0 pg/mL). At the receiver operating characteristic curve analysis, the optimal cut-off of procalcitonin was ≥0.32 ng/mL with 92% sensitivity and 98% specificity, while the most accurate threshold of calcitonin was ≥12.0 pg/mL with 100% sensitivity and 91% specificity. There was no active medullary thyroid carcinoma with simultaneously negative results of procalcitonin and calcitonin. Conclusions: Procalcitonin is reliable in discriminating medullary thyroid carcinoma patients with active disease from those with no evidence of disease. We suggest using procalcitonin as complementary to calcitonin to follow-up medullary thyroid carcinoma patients.