bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extent of resection of epidermoid tumors and risk of recurrence: case report and meta-analysis
Authors: Shear Brian M. , Jin Lan , Zhang Yawei , David Wyatt B. , Fomchenko Elena I. , Erson-Omay E. Zeynep , Huttner Anita , Fulbright Robert K. , Moliterno Jennifer 
Published: July 2019

OBJECTIVEIntracranial epidermoid tumors are slow-growing, histologically benign tumors of epithelial cellular origin that can be symptomatic because of their size and mass effect. Neurosurgical resection, while the treatment of choice, can be quite challenging due to locations where these lesions commonly occur and their association with critical neurovascular structures. As such, subtotal resection (STR) rather than gross-total resection (GTR) can often be performed, rendering residual and recurrent tumor potentially problematic. The authors present a case of a 28-year-old man who underwent STR followed by aggressive repeat resection for regrowth, and they report the results of the largest meta-analysis to date of epidermoid tumors to compare recurrence rates for STR and GTR.METHODSThe authors conducted a systemic review of PubMed, Web of Science, and the Cochrane Collaboration following the PRISMA guidelines. They then conducted a proportional meta-analysis to compare the pooled recurrence rates between STR and GTR in the included studies. The authors developed fixed- and mixed-effect models to estimate the pooled proportions of recurrence among patients undergoing STR or GTR. They also investigated the relationship between recurrence rate and follow-up time in the previous studies using linear regression and natural cubic spline models.RESULTSOverall, 27 studies with 691 patients met the inclusion criteria; of these, 293 (42%) underwent STR and 398 (58%) received GTR. The average recurrence rate for all procedures was 11%. The proportional meta-analysis showed that the pooled recurrence rate after STR (21%) was 7 times greater than the rate after GTR (3%). The average recurrence rate for studies with longer follow-up durations (≥ 4.4 years) (17.4%) was significantly higher than the average recurrence rate for studies with shorter follow-up durations (< 4.4 years) (5.7%). The cutoff point of 4.4 years was selected based on the significant relationship between the recurrence rate of both STR and GTR and follow-up durations in the included studies (p = 0.008).CONCLUSIONSSTR is associated with a significantly higher rate of epidermoid tumor recurrence compared to GTR. Attempts at GTR should be made during the initial surgery with efforts to optimize success. Surgical expertise, as well as the use of adjuncts, such as intraoperative MRI and neuromonitoring, may increase the likelihood of completing a safe GTR and decreasing the long-term risk of recurrence. The most common surgical complications were transient cranial nerve palsies, occurring equally in STR and GTR cases when reported. In all postoperative epidermoid tumor cases, but particularly following STR, close follow-up with serial MRI, even years after surgery, is recommended.
Infuse-as-you-go convective delivery to enhance coverage of elongated brain targets: technical note
Authors: Sudhakar Vivek , Naidoo Jerusha , Samaranch Lluis , Bringas John R. , Lonser Russell R. , Fiandaca Massimo S. , Bankiewicz Krystof S. 
Published: July 2019

OBJECTIVETo develop and assess a convective delivery technique that enhances the effectiveness of drug delivery to nonspherical brain nuclei, the authors developed an occipital “infuse-as-you-go” approach to the putamen and compared it to the currently used transfrontal approach.METHODSEleven nonhuman primates received a bilateral putamen injection of adeno-associated virus with 2 mM gadolinium-DTPA by real-time MR-guided convective perfusion via either a transfrontal (n = 5) or occipital infuse-as-you-go (n = 6) approach.RESULTSMRI provided contemporaneous assessment and monitoring of putaminal infusions for transfrontal (2 to 3 infusion deposits) and occipital infuse-as-you-go (stepwise infusions) putaminal approaches. The infuse-as-you-go technique was more efficient than the transfrontal approach (mean 35 ± 1.1 vs 88 ± 8.3 minutes [SEM; p < 0.001]). More effective perfusion of the postcommissural and total putamen was achieved with the infuse-as-you-go versus transfronatal approaches (100-µl infusion volumes; mean posterior commissural coverage 76.2% ± 5.0% vs 32.8% ± 2.9% [p < 0.001]; and mean total coverage 53.5% ± 3.0% vs 38.9% ± 2.3% [p < 0.01]).CONCLUSIONSThe infuse-as-you-go approach, paralleling the longitudinal axis of the target structure, provides a more effective and efficient method for convective infusate coverage of elongated, irregularly shaped subcortical brain nuclei.
THE INFLUENCE OF WORK CULTURE, MOTIVATION AND COMPENSATION TO THE PERFOMANCE OF EMPLOYEES IN GOVERNMENT
Authors: Sulaeman Maman , Marlina Lina , Yuliani Gina Nur 
Published: July 2019

The purpose of this study were to determine the effect of work culture, motivation and compensation to employee performance, to analyze the influence of corporate culture, motivation and compensation to employee performance. The object to be studied is the WTO (the regional organizations), which includes Office, the Environment Agency and the Office in the City of Tasikmalaya. The method used is descriptive method with survey method. The collection of data obtained by questionnaires, interviews, and literature. The population in this study is a civil servant at the Department, the Environment Agency and the office in the City of Tasikmalaya. By using path analysis, the results of this study showed that partially, workplace culture, motivation and compensation have a significant influence on employee performance. Simultaneously, work culture, motivation and compensation have a significant influence on employee performance, so the hypothesis is verified. This means that the work culture, motivation and compensation significantly influence employee performance.
PENGARUH DESAIN PRODUK DAN STRATEGI PEMASARAN TERHADAP KEPUTUSAN PEMBELIAN PRODUK
Authors: Dwiningwarni SS , Anjarsari Nur Maya , Syuhada' H. 
Published: July 2019

This study aims to analyze the impact of product design and marketing strategy to the purchasing decision partially, analyze the influence of design and marketing strategies on purchasing decisions simultaneously, determine which variables are the dominant influence on purchasing decisions. The research approach used is positivism with quantitative data derived from respondents' answers collected through questionnaires. The method used is the Focus Group Discussion (FGD). The sampling technique used was simple random sampling and the number of samples taken as many as 100 respondents. Analysis of the data used is multiple linear regression with Ordinary Least Square method (OLS). The results of this study are the design of the product and marketing strategies significantly influence purchasing decisions partially, product design and marketing strategies significantly influence purchasing decisions simultaneously, product design dominant influence on purchasing decisions. This means that companies must pay attention to the shape or design of a product to be manufactured or produced.
PENGARUH PERPUTARAN KAS DAN PERPUTARAN PIUTANG TERHADAP RENTABILITAS EKONOMI
Authors: Supriadi H. , Sapta W.P , Aslichah Hj. 
Published: July 2019

This study aims to identify and analyze the influence of cash turnover and accounts receivable turnover simultaneously, identify and analyze the effect of cash turnover and accounts receivable turnover of the economic profitability partially, and determine the dominant factor affecting the economic profitability. This research was conducted in cooperation with the reason that the Cooperative is a service company and trade. This research was conducted quantitative descriptive approach. The data collection is done by means of documentation and interviews were unstructured. The data used are secondary data derived from study subjects. The analytical method used is multiple linear regression with Ordinary Least Square method. The findings of this study include are: a significant difference between cash turnover and accounts receivable turnover of the economic profitability simultaneously. a significant difference between the cash turnover receivables turnover against economic profitability partially. Receivables turnover is a dominant factor affecting the economic profitability.
THE INFLUENCE OF ACCOUNTING INFORMATION SYSTEMS, LEADERSHIP STYLE, WORK MOTIVATION ON EMPLOYEES PERFORMANCE
Authors: Endarwati S , Suhendro S , Dewi R. Riana 
Published: July 2019

This study aims to test and analyze the effect of accounting information systems, leadership style and work motivation on performance garment company employees in sukoharjo.The population used in this research is the garment company employees at the accounting work on PT Danliris, PT Sunwoo Indonesia, and PT Panji Anom Setia in sukoharjo. Methods of data analysis used in this study is by purposive sampling. the number of respondents in this study as many as 38 of the 45 respondents number of questionnaires presented. Methods of analysis used was multiple linear regression analysis. The results showed that the accounting information system variables and influential work motivation and significantly to the variable performance of employees. While variable leadership style has no effect against variable employee performance. the determination coefficients (R2) of 0.415. This indicates that variansi on a variable performance practice undertaken by the company in Sukoharjo garment amounted to 41.5% can be explained by the variable accounting information systems, leadership style and work motivation, whereas the remaining 58.5 % explained by factors – factors other than that examined
TAX AWARENESS, MODERN TAX ADMINISTRATION SYSTEM AND TAX SANCTIONS AGAINST TAXPAYER COMPLIANCE
Authors: Saraswati Zulaicha Efrita , Masitoh Endang , Dewi Riana Rachmawati 
Published: July 2019

The purpose of this research is to know the influence of the consciousness of tax, the tax administration system and modern taxation sanctions against taxpayer compliance. The sample used in this study the taxpayer in the city of Surakarta. The technique of sampling is done using a purposive sampling of the dwarf. The sample of respondents in the study were 40 tax payers. Methods of analysis used was multiple linear regression analysis. Results of the study the feasibility test model (F test) shows that the independent variable (the awareness of tax, the tax administration of the modern sisem and tax penalties) influential and significantly to the dependent variables (compliance with tax payers). The results of the research hypothesis test (test t) indicates that the variable tax consciousness and modern tax administration system and significant effect against taxpayer compliance, while variable tax sanctions had no effect and no significant against taxpayer compliance.
ANALISIS KEPUTUSAN PEMBELIAN PAKET WISATA ALAM OLEH USER MEDIA SOSIAL INSTAGRAM
Authors: Purba Indra Setiawan , Ariwibowo Prasetio 
Published: July 2019

The method used in this research is descriptive analysis method, regression analysis, and hypothesis testing with simple linier regression analysis and coefficient of determination analysis. In this study, the population is a student of Jakarta Capital City who has social media instagram and has never bought natural tourism package. The validity test used in this research is using Convirmatory factor analysis (CFA) technique. The low validity of a questionnaire instrument can be measured by loading factor with SPSS 20.00 for Windows.
Based on the results of simple regression calculation obtained a = 98.145 and b = 0.27 form regression Y = 98.145 + 0.27X. Interpretation of the regression equation model is any change of X variable scores for one unit, then the variable Y increases by 0.27 in the same direction with the constant 98.14 Provided Coefficient of Determination (KD) of 0.0225, this shows that the contribution of attitude on social media instagram (X ) to the decision of purchasing natural tourism package (Y) is equal to 2,25% and contribution by other factor equal to 97.75%. Based on t arithmetic <t table (1.485 <1.984), it means there is very low influence between attitude on social media instagram to decision of purchasing nature tour package.
INTELLECTUAL CAPITAL TERHADAP KINERJA KEUANGAN PERUSAHAAN FARMASI DI INDONESIA
Authors: Sriwahyuni Diana , Hermawan Sigit , Hanun Nur Ravita 
Published: July 2019

This study aims to analyze the effects of Intellectual Capital to Financial Performances of Pharmaceutical Company. Independent variable in this study is Intellectual Capital . Intellectual Capital which consist of Human Capital (HC), Structural Capital (SC), and the Capital Employed which uses a method Value Added Intellectual Coefficients (VAICTM.). Financial Company’s Performance is proxied by Return On Assest (ROA) and Net Profit Margin (NPM).
This research samples are pharmaceutical company in the Indonesia Stock Exchange in 2011- 2015. Samples were collected by purposive sampling method and resulted in 7 firms as the samples. This study used simple linear regression to analyze data. The results of this study indicate that intellectual capital (IC) has effect on variable financial performance Return On Assets (ROA) and intellectual capital (IC) has effect on variable financial performance Net Profit Margin (NPM).
ANALISIS KEPUASAN KONSUMEN TERHADAP PRODUK ROKOK DJARUM SUPER MLD DI KALANGAN ANAK MUDA
Authors: Bernik Merita , Dwi Putra Aldy Gustian 
Published: July 2019

Today's development requires young people in Bandung to follow a lifestyle. Cigarettes are one product that can show a person's lifestyle. Although it has been socialized that cigarettes are not good for health, but because of the demands of lifestyle and influenced by relationships, many young people in the city of Bandung smoke. Many cigarette companies in Indonesia are famous for producing cigarettes that have a distinctive taste. In the research, the level of consumer satisfaction was measured by analyzing the marketing mix indicator on Djarum Super MLD cigarette products among young people in the city of Bandung.
The method of this research is descriptive method that using primary data in the form of interviews, observation and questionnaires, and also used secondary data. The smpling technique used is purposive sampling, which is a sample of young people over the age of 20 years. The results show that the level of consumer satisfaction in the city of Bandung on Djarum Super MLD cigarette products is at a good level or it can be stated that consumers are satisfied with product of Djarum Super MLD cigarette.
Analisis Kelayakan Pengoperasian Instalasi Pengolahan Air Limbah (IPAL) CV Proma Tun Probolinggo
Authors: Prihatiningsih Tri , Haryono Haryono 
Published: July 2019

Tofu is a traditional Indonesian food that is very popular with the community. The tofu production process produces solid and liquid waste. The liquid waste contains very high BOD, COD, and TSS which has the potential to pollute the environment, therefore it is necessary to have a Waste Water Treatment Plant (WWTP). This study aims to determine the economic feasibility study of the operation of the WWTP. The research was conducted at CV. Proma Tun Saroyyan Probolinggo. To find out the economic feasibility of the operation of WWTPs using the parameters of the Net Present Value (NPV), Payback Period (PP) and Benefit Cost Ratio (B / C R). The results showed that the WWTP used was the Anaerob-Biogas system, the anaerobic system is wastewater treatment by utilizing microorganisms that work without oxygen-free, with three stages, namely: Hydrolysis, Acidification, and Methane Formation Stage. The resulting methane gas (biogas) is a mixture of various types of gases, including CH4 (54% -70%), CO2 (27% -45%), O2 (1% -4%), N2 (0.5% -3%), CO (1%), and H2 which are stored in the gas holder and distributed to the community as an alternative fuel to replace LPG gas. For an analysis of economic feasibility with NPV criteria shows that the biogas WWTP is profitable because the NPV value is positive at Rp. 58,249,000. Based on the criteria of PP, which is 5 years 10 months 20 days, which means that the time is quite short and does not exceed the age of the economical gas holder. And the value of B / C Ratio is 1.4109 which means that the WWTP biogas in the CV. Proma Tun Saroyyan Probolinggo deserves to be developed because of the value of B / C R> 1.
Model DFIG Pembangkit Listrik Tenaga Angin Sebagai Suatu Unit Pembangkit Tersebar
Authors: Syahputra Ramadoni , Robandi Imam , Ashari Mochamad 
Published: July 2019

In this paper, we present the doubly-fed induction generator (DFIG) model in a wind turbine system as a unit of the distributed generator. The wind turbine driven by doubly-fed induction machine is a part of the distributed generation which feeds ac power to the distribution network. The system is modeled and simulated in the Matlab Simulink environment in such a way that it can be suited for modeling of all types of induction generator configurations. The model makes use of rotor reference frame using a dynamic vector approach for machine model. The fuzzy logic controller is applied to the rotor side converter for active power control and voltage regulation of wind turbine. Wind turbine and its control unit are described in details. All power system components and the fuzzy controller are simulated in Matlab Simulink software. For studying the performance of the controller, different abnormal conditions are applied even the worst case. Simulation results prove the excellent performance of the fuzzy controller unit as improving power quality and stability of the wind turbine.
Analisa Kapasitas Penampang Sungai Kali Gunting Di Kabupaten Jombang
Authors: Arfaah Saiful , Iswinarti Iswinarti 
Published: July 2019

The cause of flooding in the watershed area, one of which is caused by the inability of the river profile to accommodate the existing discharge (overflow). This research is intended to examine flood discharge and flood water level profile of Kali Gunting as a first step to determine flood mitigation solutions. Analysis of flood water level profiles using the Hec-Race 4.0 modeling program. With the help of this program, it is expected to be able to accommodate the flow parameters that are so complex. After modeling and knowing the capabilities of each part (cross-section), this result will be a technical reference in determining flood mitigation measures.
From the results of the study, the analysis of the potential for flooding in the scissor area was obtained as a result of the flood discharge capacity at scissors times = 301.00m3 / dt, and the emission times = 136.66m3 / dt for the 50th return period. The results of the Q50th calculation show that the condition of K. Scissors P0-P36 river water overflows / floods because the flood water level is above the existing embankment, while P36-P46 does not overflow/does not flood because the flood water level is below the existing dike. K. Panir condition P0-P48 river water overflows / floods because the flood water level is above the existing embankment, while P48-P60 does not overflow/does not flood because the flood water level is below the existing embankment
Application of variance reduction techniques in EGSnrc based Monte-Carlo method
Authors: Hoang Tuan Duc , Duong Tai Thanh , Luong Oanh Thi , Truong Loan Thi Hong 
Published: July 2019

Introduction: Monte Carlo (MC) is considered to be the most accurate method to calculate dose distribution in radiation therapy. However, the limitation of MC simulations is the long calculation time to reach the desired statistical uncertainty in the dose calculation as well as in clinical practice. To overcome the above limitations, Variance reduction techniques (VRTs) has developed and shorten the calculation time while maintaining accuracy. Therefore, the purpose of this study is the application of VRTs in code EGSnrc to find the optimal method for accelerator simulation and calculated dose distribution using MC method.
Methods: The linear Accelerator HPD Siemens Primus at the General Hospital of Dong Nai had been simulated by using BEAMnrc code and several variance reduction techniques such as: range rejection, photon forcing, bremsstrahlung photon splitting (uniform, selective and direction)... These VRTs were used under the same set of input parameters as histories of 2x108, photon energy of 6 MV, structure, size and material of the phantom… The computational efficiency ε is calculated by the following equation ε = 1/T.σ2 where T is the CUP time of calculation and σ2 is an estimate of the variance, for evaluating and selecting the VRT which gives the best computational efficiency.
Results: The results showed a good agreement between the calculated dose and measured ones when applying different VRTs. These techniques were significantly reduced uncertainty in simulation compared the analog cases. Specifically, the efficiency of DBS and UBS improved by more than 90 times and 15 times compared with the analog instances, respectively. Rang rejection and photon forcing techniques also haveimproved the efficiency of simulation, but not significantly.
Conclusions: The application of the VRTs for EGSnrc increase the efficiency of the simulation. VRTs is a powerful tool that should be applied for the simulation by code EGSnrc to improve calculation efficiency by reducing simulation time and its variance. Our results show that the direction bremsstrahlung splitting (DBS) gives thebest computational efficiency.
Üniversite Öğrencilerinin Boş zaman Anlamlarının İncelenmesi
Authors: DİNÇ Halime , KOCA H.buğra , POYRAZ Adem , AYDEMİR Kezban 
Published: July 2019

Bu araştırmanın amacı; üniversite öğrencilerinin boş zaman anlamlarının incelenmesidir. Bu araştırmanın evrenini 2017-2018 eğitim öğretim yılında Afyon Kocatepe Üniversitesi’nde farklı fakülte ve bölümlerde öğrenim görmekte olan öğrenciler oluşturmuştur. Araştırma örneklemini ise Afyon Kocatepe Üniversitesi’nin farklı fakülte ve bölümlerinde öğrenim gören 488 kadın, 473 erkek olmak üzere toplam 961 öğrenci oluşturmaktadır. Öğrencilerin yaş ortalamaları 21,54±2,09 olarak tespit edilmiştir. Araştırmada veri toplama aracı olarak, “Boş Zaman Anlamı Ölçeği” ve demografik değişkenlerden oluşan anket formu kullanılmıştır. Verilerin analizinde; betimsel istatistik yöntemleri, Independent Samples T Testi ve tek yönlü Varyans Analizi (ANOVA) testleri kullanılarak değerlendirilmiştir. Araştırmada elde edilen bulgular doğrultusunda üniversite öğrencilerinin boş zaman anlamlarının iyi seviyede olduğu belirlenmiştir. Öğrencilerin cinsiyet, fakülte, düzenli fiziksel aktiviteye katılımlarına göre boş zaman anlamlarının anlamlı fark gösterdiği tespit edilmiştir. Ayrıca üniversite öğrencilerin boş zaman anlamlarının fakülteler arası ve düzenli fiziksel aktivite yapma durumlarına göre fark gösterdiği sonucuna ulaşılmıştır. Sonuç olarak; üniversite öğrencilerinin boş zaman anlamlarının iyi seviyede olduğu, boş zaman anlamlarının kadınlarda erkeklerden daha yüksek olduğu belirlenmiştir.