bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radio-Frequency Identification Specimen Tracking to Improve Quality in Anatomic Pathology
Authors: Norgan Andrew P. , Simon Kurt E. , Feehan Barbara A. , Saari Lynn L. , Doppler Joseph M. , Welder G. Scott , Sedarski John A. , Yoch Christopher T. , Comfere Nneka I. , Martin John A. , Bartholmai Brian J. , Reichard R. Ross 
Published: June 2019

Context.—Preanalytic errors, including specimen labeling errors and specimen loss, occur frequently during specimen collection, transit, and accessioning. Radio-frequency identification tags can decrease specimen identification and tracking errors through continuous and automated tracking of specimens.Objective.—To implement a specimen tracking infrastructure to reduce preanalytic errors (specimen mislabeling or loss) between specimen collection and laboratory accessioning. Specific goals were to decrease preanalytic errors by at least 70% and to simultaneously decrease employee effort dedicated to resolving preanalytic errors or investigating lost specimens.Design.—A radio-frequency identification specimen-tracking system was developed. Major features included integral radio-frequency identification labels (radio-frequency identification tags and traditional bar codes in a single printed label) printed by point-of-care printers in collection suites; dispersed radio-frequency identification readers at major transit points; and systems integration of the electronic health record, laboratory information system, and radio-frequency identification tracking system to allow for computerized physician order entry driven label generation, specimen transit time tracking, interval-based alarms, and automated accessioning.Results.—In the 6-month postimplementation period, 6 mislabeling events occurred in collection areas using the radio-frequency identification system, compared with 24 events in the 6-month preimplementation period (75% decrease; P = .001). In addition, the system led to the timely recovery of 3 lost specimens. Labeling expenses were decreased substantially in the transition from high-frequency to ultrahigh frequency radio-frequency identification tags.Conclusions.—Radio-frequency identification specimen tracking prevented several potential specimen-loss events, decreased specimen recovery time, and decreased specimen labeling errors. Increases in labeling/tracking expenses for the system were more than offset by time savings and loss avoidance through error mitigation.
Predictive Modeling of the Human Hepatoma (Huh-7D12) Cancer Line of a Series of bis- (5-arylidene-rhodanine-3-yl) Diamine
Authors: Kouassi Koffi Alexis Respect , Benié Anoubilé , Koné Mamadou Guy-Richard , Coulibaly Wacothon Karime , Bohoussou Kouadio Valery , Ganiyou Adenidji 
Published: June 2019

This work deals with the prediction of the antiproliferative activity of eighteen (18) substances derived from bis-5-arylidene rhodanine against human hepatoma tumor line (Huh-7D12). By applying the functional density theory (DFT) method to the B3LYP / 6-31G (d, p) level, theoretical descriptors were determined and correlated with antiproliferative (Huh-7) activity by linear regression multiple (RML). This correlation has shown that the electron energy, the energy of the lowest vacant molecular orbital (ELUMO) and the molecular volume (VM) are the quantum and geometric descriptors that best influences the antiproliferative activity of the molecules studied. The coefficient of determination R2 indicates that 97.9% of the molecular descriptors defining this model are taken into account with a standard deviation of 0.015. The significance of the model reflected by the Fischer test is estimated at 123.648. The robustness of the model given by the cross-validation correlation coefficient (Q2CV) is 97.9%. This model has been validated by Tropsha criteria. The very good correlation between these three descriptors and the Huh-7 activity was confirmed by the nonlinear multiple regression (RNML) method with better statistical data. (R2 = 0,998 ; Q2CV = 0,998 ; RMSE = 0,006).
A Survey of Contraceptive Use and Associated Factors among Street Beggar Women in South Ethiopia
Authors: Alemu Shambel , Megabiaw Berihun , Lette Abate , Ermeko Tilahun 
Published: June 2019

Background: According to Ethiopian demographic and health survey 2011, contraceptive acceptance was 29%. But no evidence that shows how much it is in absolutely poorest people and what factors affect their utilization.
Objectives: This study aimed to assess prevalence of contraceptive acceptance, and associated factors among street beggar women in Hawassa town, southern Ethiopia.
Methods: A community based cross- sectional study was carried out among street beggar women from February to March 2013. An interview based pre-tested and structured questionnaire was used to collect data. Data collection sites were demarcated into churches, mosques, market areas and women begging on roads. EPI info 3.5.3, and SPSS version 20 were used to enter and analyze the data respectively and descriptive statistic and odds ratio were used to present the data. Binary and multivariate logistic regulations were performed.
Results: Three hundred forty five women participated in the study yielding response rate of 91%. The contraceptive acceptance rate prevalence was 37.4% (95% CI: 20.5, 27.3). Nearly 60% were used injectable contraceptive. Religion (AOR = 11.6, 95%CI: 2.12, 63.62), husband approved utilization (AOR = 7.68, 95%CI: 1.37, 43.15), women who have children after joining street begging (AOR = 10.18, 95%CI: 3.84, 17.26) were significantly associated with contraceptive utilization; but those who sleep at the night on the street use contraceptive less likely (AOR = 0.21, 95%CI: 0.05, 0.92).
Conclusion: This study found high prevalence of the contraceptive acceptance among beggar women in south Ethiopia. Furthermore, the study revealed that the contraceptive acceptance among beggar women is strongly associated with husband approved utilization, women who have children after joining street begging, and women who sleep the night on the street. Therefore, concerned bodies should intervene on these factors.
The impact TQM System on Supply Chain Performance through Supply Chain Integration and Employee Satisfaction
Authors: Kristianto Ivan , Tarigan Zeplin Jiwa Husada 
Published: June 2019

Indonesia has entered the Southeast Asian free trade market or better known as ASEAN Economic Community (AEC). The economic growth and the increasing number of companies annually will bring some impacts on the competitions for many companies in Indonesia, so they have find their competitive advantage. The biggest competitive advantage of Indonesia is in the primary sector companies which is producing consumer goods from natural raw materials and semi-finished goods. To win the competition, the primary sectors require product standards as the company output by implementing TQM, which usually adopts ISO as the main requirement for exporting their products. This is also the criteria for the research samples. The questionnaires are distributed to 100 companies that have over 100 employees, and the returned questionnaires are 64, with four incomplete questionnaires, making the response rate of 60%. The data analysis is using PLS and proves that all hypotheses are accepted. First, TQM implementation has a positive and significant impact on supply chain integration. Second, TQM implementations in companies are able to create a proper documentation system for each department to facilitate good communication among departments. Third, TQM implementation has a positive impact on supply chain performance and employee satisfaction. Fourth, supply chain integration has a positive impact on employee satisfaction and supply chain performance. Employee satisfaction has a positive effect on supply chain performance. The overall impact of TQM implementation on supply chain performance is 0.4680. TQM implementation brings a positive impact on supply chain integration and supply chain performance, thus increases the total impact of supply chain performance
1H‐31P magnetic resonance spectroscopy: effect of biotin in multiple sclerosis
Authors: Guillevin Carole , Agius Pierre , Naudin Mathieu , Herpe Guillaume , Ragot Stéphanie , Maubeuge Nicolas , Philippe Neau Jean , Guillevin Rémy 
Published: June 2019

AbstractBiotin is thought to improve functional impairment in progressive multiple sclerosis (MS) by upregulating bioenergetic metabolism. We enrolled 19 patients suffering from progressive MS (5 primary and 14 secondary Progressive‐MS). Using cerebral multinuclear magnetic resonance spectroscopy (MMRS) and clinical evaluation before and after 6 months of biotin cure, we showed significant modifications of: PME/PDE, ATP, and lactate resonances; an improvement of EDSS Neuroscore. Our results are consistent with metabolic pathways concerned with biotin action and could suggest the usefulness of MMRS for monitoring.
Recent Advances in the Understanding of the Evolution of Surfaces and Interfaces in Solid Oxide Cells
Authors: Skinner Stephen J. 
Published: June 2019

AbstractIn solid oxide electrochemical cells the critical processes of fuel oxidation and oxygen reduction occur at surfaces, and ultimately define the performance of the devices. Understanding how these process occur and the role of defects such as dislocations and grain boundaries in these charge transfer processes, and the effect of cation segregation on surface exchange are all topics of current significance. To address these issues, a suite of advanced analytical techniques are developed to allow in situ analysis of key processes, complementing established ex‐situ techniques. In addition the application of surface sensitive techniques such as surface diffraction and ion scattering spectroscopy, offer unprecedented levels of information on the surface chemistry and structure of functional materials.
Ammoniating Covalent Organic Framework (COF) for High‐Performance and Selective Extraction of Toxic and Radioactive Uranium Ions
Authors: Xiong Xiao Hong , Yu Zhi Wu , Gong Le Le , Tao Yuan , Gao Zhi , Wang Li , Yin Wen Hui , Yang Li Xiao , Luo Feng 
Published: June 2019

AbstractAn ideal porous adsorbent toward uranium with not only large adsorption capacity and high selectivity but also broad applicability even under rigorous conditions is highly desirable but still extremely scarce. In this work, a porous adsorbent, namely [NH4]+[COF‐SO3−], prepared by ammoniating a SO3H‐decorated covalent organic framework (COF) enables remarkable performance for uranium extraction. Relative to the pristine SO3H‐decorated COF (COF‐SO3H) with uranium adsorption capacity of 360 mg g−1, the ammoniated counterpart of [NH4]+[COF‐SO3−] affords ultrahigh uranium uptake up to 851 mg g−1, creating a 2.4‐fold enhancement. Such a value is the highest among all reported porous adsorbents for uranium. Most importantly, a large distribution coefficient, KdU, up to 9.8 × 106 mL g−1 is observed, implying extremely strong affinity toward uranium. Consequently, [NH4]+[COF‐SO3−] affords highly selective adsorption of uranium over a broad range of metal ions such as SU/Cs = 821, SU/Na = 277, and SU/Sr = 124, making it as effective uranium adsorbent from seawater, resulting in amazing uranium adsorption capacity of 17.8 mg g−1. Moreover, its excellent chemostability also make it an effective uranium adsorbent even under rigorous conditions (pH = 1, 8, and 3 m acidity).
Solvent Engineering for High‐Performance n‐Type Organic Electrochemical Transistors
Authors: Savva Achilleas , Ohayon David , Surgailis Jokubas , Paterson Alexandra F. , Hidalgo Tania C. , Chen Xingxing , Maria Iuliana P. , Paulsen Bryan D. , Petty Anthony J. , Rivnay Jonathan , McCulloch Iain , Inal Sahika 
Published: June 2019

AbstractOrganic electrochemical transistors (OECTs) exhibit strong potential for various applications in bioelectronics, especially as miniaturized, point‐of‐care biosensors, because of their efficient transducing ability. To date, however, the majority of reported OECTs have relied on p‐type (hole transporting) polymer mixed conductors, due to the limited number of n‐type (electron transporting) materials suitable for operation in aqueous electrolytes, and the low performance of those which exist. It is shown that a simple solvent‐engineering approach boosts the performance of OECTs comprising an n‐type, naphthalenediimide‐based copolymer in the channel. The addition of acetone, a rather bad solvent for the copolymer, in the chloroform‐based polymer solution leads to a three‐fold increase in OECT transconductance, as a result of the simultaneous increase in volumetric capacitance and electron mobility in the channel. The enhanced electrochemical activity of the polymer film allows high‐performance glucose sensors with a detection limit of 10 × 10−6 m of glucose and a dynamic range of more than eight orders of magnitude. The approach proposed introduces a new tool for concurrently improving the conduction of ionic and electronic charge carriers in polymer mixed conductors, which can be utilized for a number of bioelectronic applications relying on efficient OECT operation.
A prospective, multi‐center, randomized comparison of iron isomaltoside 1000 versus iron sucrose in patients with iron deficiency anemia; the FERWON‐IDA trial
Authors: Auerbach Michael , Henry David , Derman Richard J. , Achebe Maureen M. , Thomsen Lars L. , Glaspy John 
Published: June 2019

AbstractIron deficiency anemia (IDA) is prevalent, and intravenous iron, especially if given in a single dose, may result in better adherence compared with oral iron. The present trial (FERWON‐IDA) is part of the FERWON program with iron isomaltoside 1000/ferric derisomaltose (IIM), evaluating safety and efficacy of high dose IIM in IDA patients of mixed etiologies. This was a randomized, open‐label, comparative, multi‐center trial conducted in the USA. The IDA patients were randomized 2:1 to a single dose of 1000 mg IIM, or iron sucrose (IS) administered as 200 mg intravenous injections, up to five times. The co‐primary endpoints were adjudicated serious or severe hypersensitivity reactions, and change in hemoglobin from baseline to week eight. A total of 1512 patients were enrolled. The frequency of patients with serious or severe hypersensitivity reactions was 0.3% (95% confidence interval: 0.06;0.88) vs 0.4% (0.05;1.45) in the IIM and IS group, respectively. The co‐primary safety objective was met, and no risk difference was observed between groups. The co‐primary efficacy endpoint of non‐inferiority in hemoglobin change was met, and IIM led to a significantly more rapid hematological response in the first two weeks. The frequency of cardiovascular events was 0.8% and 1.2% in the IIM and IS group, respectively (P = .570). The frequency of hypophosphatemia was low in both groups. Iron isomaltoside administered as 1000 mg resulted in a more rapid and more pronounced hematological response, compared with IS, which required multiple visits. The safety profile was similar with a low frequency of hypersensitivity reactions and cardiovascular events.
Organic Ionic Crystals: Solid‐Phase Structure and Thermal Properties of Dicationic α,ω‐Bis[N,N′‐(4‐alkylpyridinium)]alkane Hexafluorophosphate Salts
Authors: Chae Hyunho , Lee A. Reum , Yoon Minyoung , Choi U Hyeok , Park Gyungse , Lee Minjae 
Published: June 2019

AbstractAs organic ionic crystals, C2‐, C3‐, and C4‐alkylene α,ω‐bis[N,N′‐(4‐alkylpyridinium)] PF6− salts are synthesized to investigate their thermal properties and phase behaviors along with chemical structure changes. The X‐ray crystal structure of 1,2‐bis[N,N′‐(4‐methylpyridinium)]ethane 2PF6− (2–1) showed that two pyridinium rings in one cation molecule and two pyridinium ring planes of neighboring molecules were exactly parallel. Multiple C−H⋅⋅⋅F hydrogen bonds were observed for all protons of the bis‐pyridinium with PF6− anions. Interestingly, most of the prepared C2‐bridged dicationic bis‐pyridinium PF6− salts showed solid–solid phase transitions, which are typical features of soft crystalline materials, such as plastic and liquid crystals. Colorfully aligned crystalline textures of the polarized optical microscope images are formed with strong birefringence for the soft crystalline phase of 1,2‐bis[N,N′‐(4‐n‐propylpyridinium)]ethane PF6−, showing a low entropy of fusion (ΔSf=25.0 J mol−1 K−1). The C2‐bridged n‐undecyl (2–11) and n‐dodecyl (2–12) salts exhibit a very soft solid phase, showing large heat absorptions and entropy changes during their multiple solid‐solid phase transitions. Additionally, the C3‐ and C4‐bridged dicationic (bis)pyridinium PF6− salts are prepared to determine the property changes with different bridge lengths. The longer alkylene connected salts are thermally more stable than the C2‐bridged compounds and show only one melting phase transition.
Interaction of music and emotional stimuli in modulating working memory in macaque monkeys
Authors: Zarei Shahab A. , Sheibani Vahid , Mansouri Farshad A. 
Published: June 2019

AbstractBackground music is one of the most frequently encountered contextual factors that affect cognitive and emotional functions in humans. However, it is still unclear whether music induces similar effects in nonhuman primates. Answering this question might bring insight to the long‐lasting question regarding the ability of nonhuman primates in perceiving and dissociating music from other nonmusical acoustic information. In the present study, macaque monkeys were trained to perform a working memory task that required matching visual stimuli. These stimuli had different emotional content (neutral, negative, and positive). Monkeys performed the task within different background acoustic conditions (music, same‐intensity noise, and silence). We hypothesized that the auditory stimuli might interact with emotional information of visual stimuli and modulate monkeys’ performance. Furthermore, if the effects of music and noise on monkeys’ behavioral measures differ it would mean that monkeys perceived and processed music differently. We found that, monkeys committed more errors and were slower when they encountered stimuli with negative or positive emotional content. In the presence of music, the influence of emotional stimuli on monkeys’ performance significantly differed from those of the neutral stimuli, however, in the presence of noise, the effects of emotional stimuli on monkeys’ performance were not distinguishable. The dissociable effects of music and noise on monkeys’ performance show that the effects of emotional stimuli were dependent on the background acoustic conditions. Our findings indicate that background music and the same‐intensity noise were differentially perceived by monkeys and influenced their cognitive functions.
Use of space and home range characteristics of Lepilemur mittermeieri, an endangered sportive lemur endemic to the Ampasindava peninsula, north‐west Madagascar
Authors: Wilmet Leslie , Beudels‐Jamar Roseline C. , Schwitzer Christoph , Rakotondrainibe Hajanirina , Devillers Pierre , Vermeulen Cédric 
Published: June 2019

AbstractLepilemur mittermeieri, a little‐studied sportive lemur of north‐west Madagascar, endemic to the Ampasindava Peninsula, faces habitat loss through forest degradation and rapid fragmentation. Understanding its habitat requirement is the first step toward preservation of this threatened forest‐dependent species. In this study, we gathered data on the use of space and home range characteristics of L. mittermeieri. We studied individuals from early March to the end of June 2015 and 2016, in three sites of the Ampasindava peninsula. We radio‐tracked 15 individuals to obtain detailed information on the size and location of home ranges (around 450 hr of tracking). Direct observation and morphometric measurements provided additional data sets. Both kernel density estimation (KDE) and minimum convex polygon (MCP) methods yielded similar home range sizes (an average of 2.01 ha with KDE method and 1.96 ha with MCP method). We did not find differences in home range size between males and females, with respect to forest type or proximity to the forest edge. Home ranges overlapped and individuals showed low levels of territoriality. We highlighted a sexually‐dimorphic trait: males have longer upper canine than females. Our results constitute the first set of ecological information on Lepilemur mittermeieri and could be the basis for a conservation strategy for this endangered species with a very small distribution area.
Socioeconomic status impacts postoperative productivity loss and health utility changes in refractory chronic rhinosinusitis
Authors: Beswick Daniel M. , Mace Jess C. , Soler Zachary M. , Rudmik Luke , Alt Jeremiah A. , Smith Kristine A. , Detwiller Kara Y. , Ramakrishnan Vijay R. , Smith Timothy L. 
Published: June 2019

BackgroundSocial determinants of health can have a substantial impact on treatment outcomes. Prior study has shown that socioeconomic status influences the likelihood of improvement in quality‐of‐life (QOL) following endoscopic sinus surgery (ESS). However, the impact of socioeconomic factors on changes in productivity loss and health utility after ESS remains unknown.MethodsAdult patients (≥18 years of age) with chronic rhinosinusitis (CRS) who underwent ESS were prospectively enrolled into a multi‐institutional cohort study. Productivity losses were calculated using the human capital approach and monetized using U.S. government–estimated wage rates. Health utility values (HUVs) were derived from the Medical Outcomes Study Short‐Form‐12 survey using University of Sheffield algorithms. Independent socioeconomic factors of interest included: age, gender, ethnicity, insurance status, educational attainment, and household income categorized via the Thompson‐Hickey model.ResultsA total of 229 patients met inclusion criteria, and 163 (71%) provided postoperative follow‐up. All subjects reported significant, within‐subject improvement in both mean monetized productivity loss (p < 0.001) and HUV postoperatively (p < 0.001). Using paired sample statistics, patients with lowest income (≤$25,000/year) and with Medicare insurance did not report significant improvement in productivity loss (p ≥ 0.112) or HUV (p ≥ 0.081), although sample size limitations may have contributed to this finding. Patients in higher income tiers ($25,001 to $100,000/year and $100,001+/year) and those with employer‐provided/private health insurance reported significant postoperative improvements in productivity loss and HUV (all p ≤ 0.003).ConclusionSocioeconomic factors, including income and insurance provision, may impact improvements in productivity loss and HUV following ESS. Further research to validate these findings, ascertain mechanisms behind these results, and improve these outcomes is warranted.
Non‐metal Single‐Iodine‐Atom Electrocatalysts for the Hydrogen Evolution Reaction
Authors: Zhao Yongqiang , Ling Tao , Chen Shuangming , Jin Bo , Vasileff Anthony , Jiao Yan , Song Li , Luo Jun , Qiao Shi‐Zhang 
Published: June 2019

AbstractCommon‐metal‐based single‐atom catalysts (SACs) are quite difficult to design due to the complex synthesis processes required. Herein, we report a single‐atom nickel iodide (SANi‐I) electrocatalyst with atomically dispersed non‐metal iodine atoms. The SANi‐I is prepared via a simple calcination step in a vacuum‐sealed ampoule and subsequent cyclic voltammetry activation. Aberration‐corrected high‐angle annular dark‐field scanning transmission electron microscopy and synchrotron‐based X‐ray absorption spectroscopy are applied to confirm the atomic‐level dispersion of iodine atoms and detailed structure of SANi‐I. Single iodine atoms are found to be isolated by oxygen atoms. The SANi‐I is structural stable and shows exceptional electrocatalytic activity for the hydrogen evolution reaction (HER). In situ Raman spectroscopy reveals that the hydrogen adatom (Hads) is adsorbed by a single iodine atom, forming the I‐Hads intermediate, which promotes the HER process.