bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of causes of delay in Indian construction projects and mitigation measures
Authors: K.V. Prasad , V. Vasugi , R. Venkatesan , Bhat Nikhil 
Published: January 2019

Purpose
Construction projects in India continue to suffer excessive delays. This paper aims to investigate the delay causes in India by project sector (transport, power, buildings and water) and carry out a comparative study of delay causes in design build (DB) projects with that of design bid build (DBB) projects along with mitigation measures.

Design/methodology/approach
A questionnaire survey was conducted among major clients, contractors and consultants in India. Importance Index was used for ranking of the delay causes. Projects were categorized based on the type, and causes of delay in each project type were identified. Projects were also categorized based on type of contract, and delay causes in DB and DBB projects were compared. Statistical analysis of responses by Cronbach’s alpha, one-way analysis of variance, Kruskal–Wallis tests was carried out with Statistical Package for Social Sciences. Semi-structured in-depth interviews were conducted with senior industry professionals to develop exhaustive mitigation measures.

Findings
The research findings indicate finance-related causes as the most critical causes of delay in Indian projects. Delay in settlement of claims, contractor’s financial difficulties, delay in payment for extra work/variations by owner, late payment from contractor to subcontractor or suppliers, variation orders/changes of scope by owner during construction and changes in design by owner were the highly ranked delay causes. The research found no significant difference in the delay causes in DB and DBB projects.

Originality/value
This is the first study wherein delay causes for various project types within a single country are identified. In addition, the study has identified and compared the delay causes in DB projects and DBB projects. Mitigation measures developed in this study will help professionals and project managers not just in India but other developing countries as well to alleviate delay causes and in improvement of project timelines.
Why is humility so relevant for leaders and can it be developed through coaching?
Authors: Aziz Khalid 
Published: January 2019

Purpose
When we think of a successful leader, we typically recall those powerful personalities we see in the media, and there have been many over the decades. They propel a company to stardom with a winning strategy, publish books, do the speaker circuits and everyone celebrates their achievements. They were undoubtedly successful, but therein lies the issue. They were successful. Things are different now. The current global landscape means problems encountered in business are increasingly complex and require a collaborative approach to solving them. No one person has all the right answers. Trial and error, embracing failure, accepting criticism and learning from past mistakes are really the only ways to succeed. And they require leaders to possess a very different set of personality traits, with humility now being one of the most important.

Design/methodology/approach
There is a paradox here between the need to develop greater humility and aspire to becoming “unsung heroes” when we are in an age where charismatic, often egocentric, leaders have celebrity status. Why is humility as a trait so important today? Is it relevant across the management spectrum, e.g. for junior/middle managers spotted as high potentials and wishing to climb the ladder, or is it simply important right at the very top of an organisation? What do HR practitioners need to know? What can HR practitioners do to develop the required levels of humility in their managers/leaders? Can you learn to become more humble through coaching? What really works in practice?

Findings
As a leadership coach, the author is often asked whether it is possible to coach an individual to develop humility, and the short answer is yes, it is possible to be coached. Most people already have humility inside them, but many leaders have learned to behave in the opposite way and adopt the traditional “hero” persona instead. They will tend to only display it if there’s a genuinely humble culture permeating the organisation from the top. Get that right and any developmental issues will typically take care of themselves. This paper explains how to take these initial steps.

Originality/value
This is useful for all HR professionals responsible for learning and development strategy in their organisations, including those who provide or specify leadership coaching as an intervention.
Lymph node metastasis in Chinese patients with clinical T1 non‐small cell lung cancer: A multicenter real‐world observational study
Authors: Chen Bing , Wang Xiaojun , Yu Xinnian , Xia Wen‐jie , Zhao Heng , Li Xiao‐fei , Liu Lun‐xu , Liu Yang , Hu Jian , Fu Xiang‐ning , Li Yin , Xu Yi‐jun , Liu De‐ruo , Yang Hai‐ying , Xu Lin , Jiang Feng 
Published: January 2019

BackgroundApproximately 8.3–15.9% of patients with clinical stage I non‐small cell lung cancer are subsequently shown to have lymph node metastasis. However, the clinical characteristics of patients with lymph node metastasis in China are not fully understood.MethodsThis is a multicenter retrospective analysis of pathological T1 non‐small cell lung cancer patients who underwent surgical resection from 2 January 2014 to 27 December 2017. Clinical and pathological information was collected with the assistance of the Large‐scale Data Analysis Center of Cancer Precision Medicine‐LinkDoc database. The clinical and pathological factors associated with lymph node metastasis were analyzed by univariate and multivariate logistic regression.ResultsA total of 10 885 participants (51.6% women; 15.3% squamous cell carcinoma) were included in the analysis. The median age was 60.0 years (range 12.9–86.6 years). A total of 1159 patients (10.6%) had metastases in mediastinal nodes (N2), and 640 patients (5.9%) had metastasis in pulmonary lymph nodes (N1). Most patients had T1b lung cancer (4766, 43.8%). Of the patients, 3260 (29.9%) were current or former smokers. The univariate and multivariate analyses showed that younger age, squamous cell carcinoma, poor differentiation, larger tumor size, carcinoembryonic antigen level ≥5 ng/mL, and vascular invasion (+) were significantly associated with higher percentages of lymph node metastases (P < 0.001 for all).ConclusionThis real‐world study showed the significant association of lymph node metastasis with age, tumor size, histology and differentiation, carcinoembryonic antigen levels, and status of vascular invasion. Female patients with T1a adenocarcinoma in the right upper lobe barely had lymph node metastasis.
The use of cinacalcet for the treatment of calciphylaxis in patients with chronic kidney disease: A comprehensive review
Authors: Deen Jacqueline , Schaider Helmut 
Published: January 2019

AbstractCalciphylaxis is a rare but life‐threatening condition, most commonly affecting patients with stage 4 or 5 chronic kidney disease. No universally accepted therapy exists so far. In an attempt to avoid surgical intervention with parathyroidectomy, which is of questionable efficacy and carries several risks, a number of noninvasive treatments have been trialled with variable success. These treatments are aimed at modifying risk factors for calciphylaxis, in particular hypercalcaemia, hyperphosphataemia and hyperparathyroidism. The aim of this review was to summarise the available evidence to determine the potential role of cinacalcet in the treatment of calciphylaxis in patients with chronic kidney disease. Demographic, clinical and laboratory data were retrospectively collected from the available English and non‐English literature. Overall, there was a very high response rate (partial or complete) of calciphylaxis lesions to both cinacalcet monotherapy and cinacalcet as part of a combination therapy (83.4% and 82.8%, respectively). When examining complete response to treatment specifically, combination therapy with cinacalcet proved more efficacious than monotherapy (62.1% versus 41.7%). There was also an associated rapid reduction of intact parathyroid hormone over a period of 2–33 months in both groups. While there are limitations as to how our data can be interpreted due to the heterogeneity of the methods and follow‐up of the included case reports and case series, prompt and consistent therapy including cinacalcet may help improve the disease outcome. Additional research needs to be performed in this area, to further define the optimal use of cinacalcet for the treatment of calciphylaxis.
Demand complementarities and cross‐country price differences
Authors: Murphy Daniel 
Published: January 2019

AbstractEmpirical studies document that markups vary across destinations. This paper proposes a novel mechanism to explain variation in markups: consumers’ utility from final goods and services depends on their consumption of complementary goods and services. In countries with more complementary goods and services, consumer demand is less elastic, enabling monopolistically competitive firms to charge higher prices. The paper provides empirical evidence documenting a dependence of prices on demand complementarities.
Disseminated herpes zoster following treatment with benralizumab
Authors: Mishra Ajay Kumar , Sahu Kamal Kant , James Atem 
Published: January 2019

AbstractBackgroundDisseminated herpes zoster infection occurs mostly in immunocompromised hosts. There have been recent reports of disseminated zoster with chemotherapeutic regimens and newer monoclonal antibodies.Case reportThe present case describes a 61‐year‐old patient presenting with disseminated herpes zoster after initiation of benralizumab, an anti‐IL‐5 monoclonal antibody for severe persistent asthma. His initial vesicular lesions limited to left lumbar dermatomes progressed extensively resulting in dissemination on his body. The diagnosis was confirmed with PCR and he had remarkable clinical improvement with acyclovir and supportive medical management.ConclusionClinical trials have reported an association of mepolizumab, another anti‐IL‐5 monoclonal antibody with herpes zoster. This report of herpes zoster following initiation of benralizumab might suggest a possibility of a class effect of anti‐IL‐5 monoclonal antibody.
Fragments of an anti‐fascist geography: Interrogating racism, nationalism, and state power
Authors: Ince Anthony 
Published: January 2019

AbstractExtensive research exists in geography concerning racism and nationalism, yet there has been surprisingly little written on the far right, and even less on their anti‐fascist opponents. In the context of a resurgent far right, this paper draws together disparate work on this topic within geography to investigate the possibilities for the development of anti‐fascist geographies. While fascism and anti‐fascism have been chronically under‐researched in geography, I argue that there remains an insightful body of research in existence and that geographers are well positioned to undertake substantial work on the subject. Three connecting dimensions of an anti‐fascist geography are identified, namely, investigating not only racism but also the more‐than‐racist dimensions of the far right; their intersections with one another; and the development of anti‐fascist rationalities in geographical scholarship. Through this discussion, I suggest that the field of anarchist geographies offers a useful framework for these tasks, not only for empirical study but also for developing agendas to embed anti‐fascist principles into academic practices. By focusing in on the spatialities of far right and anti‐fascist politics, political geographers can position themselves at the forefront of this important area of work.
Transnational migrant entrepreneurship, gender and family business
Authors: VERSHININA NATALIA , RODGERS PETER , MCADAM MAURA , CLINTON ERIC 
Published: January 2019

AbstractDespite increased academic attention paid to migration flows in Europe, the gendered nature of transnational migrant entrepreneurial journeys within the context of a family business remains under‐researched. We address this gap by investigating how transnational spaces allow women to challenge dominant ideas about their roles, and to claim legitimacy by opening branches of their family business abroad. With extensive longitudinal evidence collected over a seven‐year period, we showcase four biographical narratives of women operating transnational family businesses in the UK that had originated in Eastern Europe. Adopting this novel longitudinal approach, we provide insights into how these transnational migrant women entrepreneurs exercise individual agency to overcome structural constraints by developing strategies that prioritize their own business aspirations without fully sacrificing their family ties.
Supercritical CO2 extraction of grape seeds oil: scale‐up and economic analysis
Authors: Duba Kurabachew , Fiori Luca 
Published: January 2019

SummaryThis work presents a scale‐up and feasibility study for the establishment of supercritical CO2 extraction plants to produce grape seeds oil. The scale‐up factors are determined using experimental and modelling results based on seeds from six grape cultivars over 2 harvest years. The purchased cost of the production plant is estimated using ‘the six‐tenth rule’ from the cost of a pilot scale unit. The results indicate that, at the current minimum retail selling price of extra virgin grape seeds oil, the proposed project is technically viable and economically feasible with a breakeven point of US$ 7.46 per kg‐oil and rate of return on investment of 28%.
Differential role of the NLRP3 inflammasome in infection and tumorigenesis
Authors: Tartey Sarang , Kanneganti Thirumala‐Devi 
Published: January 2019

SummaryDysregulated inflammation is one of the hallmarks of cancer initiation and progression. Emerging evidence indicates that inflammasomes play a central role in regulating immune cell functions in various infections and cancer. Inflammasomes are multimeric complexes consisting of nucleotide‐binding oligomerization domain (NOD) ‐like receptors (NLRs). Among the NLRs, NOD1, NOD2 and NLRP3 respond to a variety of endogenous (i.e. damage‐associated molecular patterns) and exogenous (i.e. pathogen‐associated molecular patterns) stimuli. The NLRP3 inflammasome is associated with the onset and progression of autoinflammatory and autoimmune diseases, including metabolic disorders, multiple sclerosis, inflammatory bowel disease, and cryopyrin‐associated periodic fever syndrome. NLRP3 is also associated with a wide variety of infections and tumorigenesis that are closely correlated with chemotherapy response and prognosis. In this review, we explore the rapidly expanding body of research on the expression and functions of NLRP3 in infections and cancers and outline novel inhibitors targeting the NLRP3 inflammasome that could be developed as therapeutic alternatives to current anticancer treatment.
The use of technology for mental healthcare delivery among older adults with depressive symptoms: A systematic literature review
Authors: Harerimana Boniface , Forchuk Cheryl , O'Regan Tony 
Published: January 2019

AbstractDepression has been identified as the single largest contributor to poor health and functioning worldwide. Global estimates indicate that 4.4% of the world's population lives with depression, equating to about 322 million individuals. Research demonstrates that telehealth interventions (i.e. delivering therapy by phone or videoconferencing) have potential for improving mental health care among community‐based older adults. This review analyses scholarly literature on telehealth interventions among older adults with depressive symptoms. Following PRISMA guidelines, a systematic search of peer‐reviewed papers was conducted using the following key terms: telemedicine, telepsychogeriatrics, telepsychiatry, eHealth, mental health, depression, and geriatric. The review included nine articles examining telehealth for mental health care, published in English between 1946 and 26 September 2017. Telehealth for mental health care among older adults demonstrates a significant impact on health outcomes, including reduced emergency visits, hospital admissions, and depressive symptoms, as well as improved cognitive functioning. Positive or negative influences on the use of telehealth among older adults are identified. This review highlights keys aspects to consider in using telehealth interventions, including levels of education, cognitive function, and prior technology experience. The review highlights vital factors for designing interventions which aim to capitalize on the benefits of the use of telehealth for mental healthcare service delivery, especially in older adults with depressive symptoms.
The effectiveness of bedside handovers: A multilevel, longitudinal study of effects on nurses and patients
Authors: Malfait Simon , Eeckloo Kristof , Van Biesen Wim , Van Hecke Ann 
Published: January 2019

AbstractAimsTo investigate the effectiveness of bedside handovers. For nurses, effects on nurse–patient communication, individualized care, coordination of the care process, job satisfaction, intention to leave, patient participation and work interruptions were measured. For patients, effects on patient activation, individualized care and quality of care were measured.DesignThis is a longitudinal, controlled, multicentred study on 13 nursing wards in five hospitals. The seven interventional wards consisted of two medical rehabilitation, two geriatric and three surgical/medical wards.MethodsA questionnaire for patients and nurses at baseline (May–June 2016), 3 (July–August 2017) and 9 months (December 2017–January 2018) after implementation was completed by 799 patients and 165 nurses. Per protocol analysis was used in combination with linear mixed models analysis.ResultsWith exception for work interruptions and patient participation for nurses, no overall effects could be found for both patients and nurses. For nurses, patient participation increased, and work interruptions decreased in the intervention group. Individualized care remained stable in the intervention group, whereas it decreased in the control group.ConclusionThe results indicate that bedside handover can be regarded as superior to more commonly used handover models as it enhances patient participation and decreases work interruptions. However, the positive image of bedside handovers, mostly based on observational, short‐term and single‐centred experiences, cannot be confirmed as there were no effects on any of the other measured parameters. As bedside handovers put patient participation on the agenda and negative effects are absent, implementing bedside handovers should be considered a mean for more patient‐centeredness instead of a goal itself.
Stigma as framed onYouTube: Effects of personal experiences videos on students’ beliefs about medicalizing intersex
Authors: Hegarty Peter , Smith Annette , Bogan‐Carey Tadhg 
Published: January 2019

AbstractPeople with physical intersex characteristics can be subject to medical interventions that risk human rights to bodily integrity and self‐determination. Proponents and opponents of medicalization use personal narrative videos on YouTube to frame intersex as a stigma best understood through amedicalorsocial identityframe. Ninety‐nine psychology students watched one of twoYouTubevideos with either a medical or social identity frame, or participated in a comparison group who watched no video. Participants extracted the videos’ medical or social identity framing in their own words. The social identity video increased participants’ sense that medicine was more harmful and less beneficial, and the medical video decreased participants’ sense that medicine was harmful. Although the videos aimed at bringing about social understanding of intersex people, neither video impacted stigmatizing beliefs about intersex people as a group. Rather, effects of the videos on beliefs about harms of medicalization were moderated by two stigma measures; social distance and gender binary beliefs. Medical intervention on intersex has been justified, in part, on grounds that stigma is inevitable. While intersex stigma has rarely been empirically examined, the present study shows that people with less propensity to stigmatize see less benefit from medicalizing intersex traits and are more open to learning few framings from personal experience videos.
Complementing the Pleistocene biogeography of European amphibians: Testimony from a southern Atlantic species
Authors: Sánchez‐Montes Gregorio , Recuero Ernesto , Barbosa A. Márcia , Martínez‐Solano Íñigo 
Published: January 2019

AbstractAimTo reconstruct the historical biogeography of Hyla molleri, a tree frog endemic to the Eurosiberian and Mediterranean bioclimatic zones in the Iberian Peninsula.LocationIberian Peninsula.MethodsWe used molecular data (mtDNA and species‐specific, polymorphic microsatellite loci) and species distribution modelling (SDM) from the Last Interglacial (LIG) to the present to characterize spatial patterns of genetic diversity in this species and assess their relationship with climatically favourable areas through time.ResultsGenetic diversity is heterogeneously distributed across the range of H. molleri, with two main genetic reservoirs located in (a) central and southern Portugal and (b) a fragmented area encompassing mountainous areas in northern Spain. According to SDM, the Iberian Peninsula has experienced a progressive and continuous decrease in climatically favourable areas for H. molleri since the LIG, especially in southern and eastern Iberia, where the species is currently absent. However, we found no correlation between areas that have remained climatically favourable since the LIG and current genetic diversity.Main conclusionsOur results suggest that the demographic history of H. molleri since the Pleistocene has been characterized by relative stability, contrasting with the large‐scale cycles of extinction‐recolonization inferred for other more thermophilous, co‐distributed amphibian species in Iberia. Accounting for discordant demographic responses to climatic changes across syntopic species provides new insights about the evolutionary history of amphibian communities in southern Europe.
How to rely on the unreliable: Examples from Mesozoic bryophytes of Transbaikalia
Authors: Mamontov Yuriy S. , Ignatov Michael S. 
Published: January 2019

AbstractThree new fossil bryophytes are described from Jurassic and Lower Cretaceous deposits of the Transbaikalia region of Russia. The complex thalloid hepatic Khasurtythallus monosolenioides gen. et sp. nov. belongs to the Marchantiidae, but its combination of characters precludes unequivocal placement in any of the five orders of this subclass, representing most likely an extinct lineage. Paleaethallus squarrosus gen. et sp. nov. is a thalloid plant with scales similar to those of complex thalloid hepatics, although their arrangement and the overall plant structure has little in common with any extant hepatics. Dispersed moss capsules, three of which have attached calyptrae, are described as a form genus Kulindobryum gen. nov. Despite incomplete preservation, some rare characters indicate possible relationship to the genus Tayloria of the Splachnaceae, an extant family of mosses adapted to grow on animal dung, dead bodies and bones. Notably, Kulindobryum co‐occurs with bones of the small feathered dinosaurs Kulindadromeus, which also supports an affiliation of Kulindobryum with the Splachnaceae. The most common and best known Mesozoic moss for the region, the genus Bryokhutuliinia, is appraised for its systematic position and probable affinities with the Dicranales. A scoring approach is introduced for the comparative method of taxonomic placement of fossils with partial suites of morphological characters at the family or order level.