bluuebunny/crossref_metadata_2025_split huggingface dataset:
Socially responsible leadership practices in university context: a developing nation perspective
Authors: Kyambade Mahadih , Namatovu Afulah , Namubiru Bridget , Muganzi Clare 
Published: December 2024

PurposeThe purpose of the study is to determine the degree to which Uganda’s public universities feel obligated to adopt socially responsible leadership practices and, in turn, live up to the expectations of their stakeholders. A crucial component of higher education institutions is socially responsible leadership in universities.Design/methodology/approachA total of 22 leaders of Uganda’s public universities participated in semi-structured interviews that the researchers conducted. Four main themes emerged from thematic analysis of the gathered data.FindingsThe researchers discover that although the leaders are willing to act appropriately in accordance with social norms, they do not fully exercise the four dimensions (moral excellence in character, stakeholder collaboration, personal abilities and moral direction). The respondents also went on to explain that they were unsure about how to start helping their societies function better as a whole.Originality/valueAs far as the researchers are aware, this is the first study to look empirically into socially responsible leadership practices in a university setting (public universities in this case), especially in developing and Orient countries.
Developing and marketing mobile health applications for low-income working adults in Hong Kong
Authors: Chan Kara , Zhuo Yuyuan 
Published: December 2024

Purpose
Despite the potential of mobile health applications in reducing barriers to accessing health information and facilities, the adoption and usage of such applications were low among low-income populations. This study aims to examine the use of mobile technology for health management and the perceived barriers of the use of mobile applications for health management among low-income working adults in Hong Kong.

Design/methodology/approach
Semi-structured interviews were conducted with 16 working adults aged 25–45 from low-income families. The interviewees were asked about their perceptions of their health, their perceptions about and use of mobile health applications and they were asked to describe their ideal mobile health management app.

Findings
Interviewees often suffer from physical pain and many face relationship difficulties. They seek out health information actively on the internet, often using a mobile phone. However, their use of wearables and health mobile applications is limited. The perceived barriers of using mobile health applications included perceived difficulties in downloading and registering, privacy concerns and a lack of awareness of the health apps available. They prefer internet searching to a dedicated app. Their ideal health applications should be video based with real-life narratives. They were concerned about the credibility of the health information provided and preferred apps that engage professional and authoritative sources.

Research limitations/implications
The study was based on a convenience sample recruited through a nonprofit organization. It has the limitation of generalizing the results for the target population. Future studies can use survey methodology to test a theoretical model linking perceived barriers and intention to use mobile health technology. Studies using experimental design can investigate perceived ease of use and perceived benefits of different mobile health app designs.

Practical implications
These findings can inform the government’s health department and health organizations in designing appropriate mobile health applications that target those with limited financial and time resources.

Originality/value
There is a lack of studies that explore perceived barriers of adoption of mobile health technology in developed societies. To the best of the authors’ knowledge, this is the one of the first qualitative studies conducted in Hong Kong among low-income working adults about their health conditions and usage of mobile health technology.
The evolution of digitainability in the fashion industry: a bibliometric analysis
Authors: Gazzola Patrizia , Grechi Daniele , Iliashenko Iuliia , Pezzetti Roberta 
Published: December 2024

Purpose This study investigates the evolution of digital transformation research trends in the context of the fashion industry. The paper analyzes and addresses the impact of digital innovations on three areas of the industry: products, processes and business models.Design/methodology/approach The study examined 277 peer-reviewed articles using various bibliometric tools and indicators, aiming to identify and organize the contributions of the most influential works. Additionally, a critical review of the ten most cited papers in the field was carried out.Findings The study shows that digitalization is not merely a technological trend; rather, it is a transformative force reshaping the fashion industry. It fosters collaboration, innovation and sustainability, creating an ecosystem where businesses can thrive by aligning with circular principles and leveraging digital tools.Research limitations/implications The paper reveals a gap in the scientific systematization and exploration of the variety of applications of digital tools in the fashion industry. The study’s limitations include the keywords chosen for the research and the period of the research from 1998 to 2023.Originality/value The paper pursues to contribute to the current discussion on sustainable practices within the fashion industry, while also setting the foundation for future progress in digital innovation that supports the increasing need for sustainable and personalized products.
Patient experiences of behavioural therapy for bipolar depression: A qualitative study
Authors: Yilmaz Sakir , Hancox Anna , Price Molly , Regan Jemma , Dunn Barney , O'Mahen Heather , Wright Kim 
Published: December 2024

AbstractBackgroundAlthough multiple qualitative studies have explored participants' experiences of behavioural activation (BA) for unipolar depression, none have investigated the experiences of BA in people with bipolar depression. This is of particular interest because qualitative studies concerning the experience of receiving therapy can help inform the theory of change underpinning the intervention.AimThe purpose of this study was to explore the experiences and perspectives of individuals with bipolar disorder who received a course of one‐to‐one BA for bipolar depression. We sought to explore participants' experience of the effects of BA therapy, both proximally and distally.MethodSemi‐structured interviews were conducted with nine individuals meeting research diagnostic criteria for bipolar I or II disorder who had received up to 20 sessions of BA adapted for bipolar depression. Thematic analysis using a framework approach was used to explore and describe the experiences of participants.ResultsParticipants' perspectives on the impact of therapy were categorized under four subthemes: client behaviour inside and outside sessions, changes in clients' perspectives, the impact on symptoms and impact on life and functioning.ConclusionsParticipants' accounts of the impact of therapy were broadly consistent with the theory underpinning a behavioural approach. Participants described a central role for perspective change, and particularly increased acceptance of the self and mood states, as facilitating behavioural changes and more distal benefits. Process evaluations embedded in future trials may include quantitative measures of key processes described by our participants, as well as those clearly implied by the behavioural theory of depression.
A Novel Compound Ligusticum Cycloprolactam Alleviates Neuroinflammation After Ischemic Stroke via the FPR1/NLRP3 Signaling Axis
Authors: Gao Juan , Su Gang , Liu Jifei , Song Jinyang , Chen Wei , Chai Miao , Xie Xiaodong , Wang Manxia , Liu Junxi , Zhang Zhenchang 
Published: December 2024

ABSTRACTBackgroundMicroglia/macrophages, as pivotal immune cells in the central nervous system (CNS), play a critical role in neuroinflammation associated with ischemic brain injury. Targeting their activation through pharmacological interventions represents a promising strategy to alleviate neurological deficits, thereby harboring significant implications for the prevention and treatment of ischemic stroke. Ligusticum cycloprolactam (LIGc), a novel monomeric derivative of traditional Chinese medicine, has shown potential as a therapeutic agent; however, its specific role in cerebral ischemic injury remains unclear.MethodsIn vitro experiments utilized lipopolysaccharide (LPS)‐induced inflammation models of RAW264.7 cells and primary mouse microglia. In vivo studies employed LPS‐induced neuroinflammation models in mice and a transient middle cerebral artery occlusion (tMCAO) mouse model to evaluate the impact of LIGc on neuroinflammation and microglia/macrophage phenotypic alterations. Further elucidation of the molecular mechanisms underlying these effects was achieved through RNA‐Seq analyses.ResultsLIGc exhibited the capacity to attenuate LPS‐induced production of pro‐inflammatory markers in macrophages and microglia, facilitating their transition to an anti‐inflammatory phenotype. In models of LPS‐induced neuroinflammation and tMCAO, LIGc ameliorated pathological behaviors and neurological deficits while mitigating brain inflammation. RNA‐seq analyses revealed formyl peptide receptor 1 (FPR1) as a critical mediator of LIGc's effects. Specifically, FPR1 enhances the pro‐inflammatory phenotype of microglia/macrophages and inhibits their anti‐inflammatory response by upregulating NLR family pyrin domain protein 3 (NLRP3) inflammasomes, thus aggravating inflammatory processes. Conversely, LIGc exerts anti‐inflammatory effects by downregulating the FPR1/NLRP3 signaling axis. Furthermore, FPR1 overexpression or NLRP3 agonists reversed the effects of LIGc observed in this study.ConclusionOur findings suggest that LIGc holds promise in improving ischemic brain injury and neuroinflammation through modulation of microglia/macrophage polarization. Mechanistically, LIGc attenuates the pro‐inflammatory phenotype and promotes the anti‐inflammatory phenotype by targeting the FPR1/NLRP3 signaling pathway, ultimately reducing inflammatory responses and mitigating neurological damage.
Machine learning derived physical activity in preschool children with developmental coordination disorder
Authors: Letts Elyse , King‐Dowling Sara , Kwan Matthew Y. W. , Obeid Joyce , Cairney John , Trost Stewart G. 
Published: December 2024

AbstractAimTo compare the device‐measured physical activity behaviours of preschool children with typical motor development to those with probable developmental coordination disorder (pDCD) and at risk for developmental coordination disorder (DCDr).MethodA total of 497 preschool children (4–5 years) in the Coordination and Activity Tracking in CHildren (CATCH) study completed repeated motor assessments and wore an ActiGraph GT3X on the right hip at baseline for 1 week. We calculated physical activity metrics from raw accelerometer data using a validated random forest classification machine learning model for preschool‐age children. Analysis of variance (ANOVA) and linear regression models compared physical activity between typically developing children, children at risk for DCDr, and those with pDCD identified based on motor scores at baseline and averaged over time, accounting for age, sex, and accelerometer wear time.ResultsWe found no differences in daily time spent sedentary, in light physical activity, or moderate‐to‐vigorous physical activity between typically developing children, children at risk for DCDr, and those with pDCD. However, children in the DCD groups spent less time doing ambulatory activities (walking/running) than typically developing children. Analysis of variance: baseline classification, DCDr to typically developing, run: F = 5.34, p = 0.005, classification averaged over time, DCDr to typically developing, walk: F = 5.82, p = 0.003. Regressions: DCDr compared to typically developing for walk: B = −3.47 (standard error 1.05), p < 0.001, pDCD compared to typically developing for run: B = −1.82 (standard error 0.62), p = 0.004.InterpretationDesigning interventions for preschool children with motor difficulties targeting specific physical activity types (walk/run) may help mitigate physical activity intensity differences observed later in childhood.
Mental Health Literacy Buffers the Association Between Nightmare Distress and Psychotic‐Like Experiences Among College Students
Authors: Chen Xingyu , Xu Bingna , Wang Dongfang 
Published: December 2024

ABSTRACTBackgroundNightmares may lead to psychotic‐like experiences (PLEs). The present study aimed to examine the potential moderating and mediating effects of mental health literacy (MHL) on the association between nightmare distress (ND) and PLEs among Chinese college students.MethodsA total of 4000 college students who have had nightmares in the past year were assessed using the Chinese version of the nightmare distress questionnaire (NDQ‐CV), mental health knowledge questionnaire (MHKQ), 15‐item positive subscale of the community assessment of psychic experiences (CAPE‐P15), 2‐item insomnia questionnaire, 2‐item patient health questionnaire (PHQ‐2), and a self‐compiled sample characteristics questionnaire.ResultsGreater ND and lower MHL were associated with an elevated risk of PLEs among college students when adjusting for sample characteristics, insomnia and depressive symptoms. Moderation analysis indicated that MHL buffers the association between ND and PLEs, such that a higher level of MHL attenuates the positive effect of ND on PLEs to a greater extent.ConclusionsThese findings strongly stressed the urgent need for early intervention in college students with ND. Strategies should prioritise treating ND and enhancing MHL, as these may be effective approaches to preventing and reducing PLEs.
Transition and Artificial Intelligence: The Case of Student Professionalisation
Authors: Capogna Stefania , Pellegrini Sara , Sebastiani Riccardo 
Published: December 2024

ABSTRACTThe article explores the importance of university students' knowledge of the world as an essential prerequisite for facing digital, ecological and human transitions. A study of 50 third‐year students of primary education sciences investigates (a) familiarity with reflection during learning; (b) the influence of artificial intelligence in the construction of knowledge; and (c) the degree of trust placed in AI to improve skills. The aim is to highlight students' metacognitive attitude towards AI, its creative use and the beliefs that emerged in their professional development.
Associations between sleep parameters and falls among older adults with and without cardiovascular disease: Evidence from the China Health and Retirement Longitudinal Study (CHARLS)
Authors: Wu Xinze , Ebihara Satoru 
Published: December 2024

AimFalls are a major global public health concern, requiring early screening and prevention. Cardiovascular disease (CVD) is associated with physical impairments and increased fall risk. Despite the link between CVD and sleep parameters, research on falls and sleep in CVD patients is limited. We aimed to compare the correlation between falls and sleep in populations with and without CVD to develop fall prevention strategies.MethodsThis longitudinal cohort study utilized data from the China Health and Retirement Longitudinal Study (CHARLS). Baseline data were collected in 2011, with follow‐up in 2015. Falls and CVD were assessed based on self‐reporting. Sleep parameters, including nighttime and total sleep duration, daytime napping, and sleep disturbance were collected via self‐reported questionnaires. Data analysis was conducted using SPSS and R statistical.ResultsA cohort of 4349 individuals with an average age of 68.00 ± 5.97 years was analyzed. From these individuals, 21.5% reported falls during follow‐up. Baseline CVD was significantly associated with follow‐up falls (P < 0.001). After adjusting for multiple factors, nighttime sleep durations of <6 h (P = 0.004), 8 to 9 h (P = 0.016) and >9 h (P = 0.031) were significantly associated with follow‐up falls among the CVD group. Total sleep duration <7 h was significantly associated with follow‐up falls in both the total and non‐CVD groups (P < 0.05).ConclusionsMaintaining a moderate sleep duration is crucial for preventing falls among older adults. Both excessively short and long sleep durations are associated with fall risks, particularly for individuals with CVD. Geriatr Gerontol Int 2025; 25: 38–47.
Employment‐based visas: The inflexible U.S. Visa regime and the impact(s) on immigrant labour market integration
Authors: Obinna Denise N. , Bacong Adrian M. 
Published: December 2024

AbstractEconomic migrants play an important role in the fiscal stability of the United States. Focusing on economic‐based (EB) green cards, our work presents an incongruence between labour demands of the American economy and the supply of highly skilled economic migrants. Using data from the United States Department of Justice and the Immigration and Naturalization Service (INS) from 1971 to 2000 as well as data from the 1990 to 2022 Visa Bulletins, we show that visa caps have meant that migrants from countries like China, India and the Philippines have had to wait between 12 and 15 years for their visas to be processed. We also show that the visa backlog accelerated in the 1990s, 2000s and 2010s despite the labour demands of the American economy. Currently, there are over 1.2 million people in the EB visa queue. Our work lays out the complexities of the visa system and advances policy recommendations to alleviate backlogs.
Assessing the Link Between Environmental Quality and Life Expectancy in Developing Nations: An Empirical Analysis for Sustainable Development
Authors: Khan Farah , Sarwar Ghulam , Khan Muhammad Azam , Noor Sameena , Rehman Zia Ur 
Published: December 2024

ABSTRACTThis study examines the relationship between environmental quality, measured by carbon emissions (CO2), and life expectancy (LE) in 31 developing nations from 1981 to 2020. The analysis uses the panel autoregressive distributed lag (ARDL)/pooled mean group (PMG) approach. Panel cointegration tests suggest cointegration in the series. The results indicate that environmental quality has a significantly negative impact on LE, whereas real gross domestic product (GDP) per capita and the age dependency ratio have positive effects. The Dumitrescu–Hurlin Granger causality test shows a feedback relationship among all variables. These findings suggest the need for emission reduction policies to mitigate the adverse effects of CO2 emissions on public health. It is essential to address the negative impact of CO2 emissions on the environment and public health to achieve sustainable development goals.
Brugada Phenocopy Induced by BRAF and MEK Inhibitors in a Lung Adenocarcinoma
Authors: Portolan Leonardo , Ruzzarin Alessandro , Vassanelli Francesca , Ribichini Flavio , Mugnai Giacomo 
Published: December 2024

ABSTRACTManagement of patients with drug‐induced type 1 Brugada pattern is complex and controversial. We report the case of a 66‐year‐old man affected by metastatic lung adenocarcinoma with type 1 Brugada phenocopy at electrocardiogram (ECG) after initiation of an oncological therapy with BRAF and MEK inhibitors.
Six‐fold increased risk of acute pancreatitis in alcohol‐related liver disease compared to matched comparators: A population‐based cohort study
Authors: Dugic Ana , Widman Linnea , Löhr J.‐Matthias , Hagström Hannes 
Published: December 2024

AbstractBackground and AimsPatients with alcohol‐related liver disease (ALD) might be at increased risk of acute pancreatitis (AP), but large‐scale data are lacking.MethodsPopulation‐based cohort study using data from the Swedish National Patient Register on 37,062 patients with ALD from 1969 to 2020. Patients were matched to ≤10 general population comparators (n = 352,931). We used logistic regression to estimate the risk of acute or chronic pancreatitis prior to ALD diagnosis and Cox regression to estimate rates for hospitalization for AP after ALD diagnosis.ResultsMedian age at ALD diagnosis was 59 years; 72% were men, and 67% had cirrhosis at baseline. Overall, 7% had experienced pancreatitis before ALD diagnosis, resulting in 9‐fold higher odds of pancreatitis compared to comparators. The 10‐year cumulative incidence of hospitalization for AP was 2.7% (95%CI = 2.5–2.8) in ALD and 0.6% (95%CI = 0.58–0.63) in comparators, yielding an adjusted HR of 6.3 (95%CI = 5.8–6.9). Younger age, male sex, and diagnoses of alcohol use disorders and chronic obstructive pulmonary disease were independent risk factors for developing AP in ALD. Continued drinking after baseline was associated with a higher risk of AP (adjusted hazard ratio [aHR] 2.6, 95%CI = 2.29–2.85).ConclusionsALD is associated with 9‐fold higher odds of prevalent pancreatitis compared to the general population. The hospitalization rate for AP following ALD diagnosis is 6‐fold higher. About 10% of patients with ALD have or develop AP, suggesting that assessing history of pancreatitis and its sequelae might be relevant for patients with ALD.
Distal His Pacing Promotes Reverse Remodeling in a Child With Conventional Pacing‐Induced Ventricular Dysfunction
Authors: Marzia Giaccardi , Mattia Zampieri , Elena Crudeli , Stella Cartei , Tania Chechi , Simone Cipani , Silvia Passantino , Giulio Porcedda 
Published: December 2024

ABSTRACTChildren with indications of pacing often require epicardial pacemakers with generators implanted in the abdominal wall due to small body size or challenging anatomy because of congenital heart diseases. However, left ventricle (LV) systolic dyssynchrony induced by epicardial pacing may result in adverse remodeling and LV dysfunction. Recently, distal His bundle pacing (dHBP) has been shown to restore normal ventricular function in adult patients with pacemaker induced ventricular dysfunction. Nevertheless, the effects and relevance of HBP in pediatric patients are largely unresolved, with only limited data analyzing the feasibility and efficacy of HBP in the pediatric population. We report the case of a young girl with congenital atrioventricular (AV) block who developed LV dysfunction induced by prolonged epicardial stimulation. After upgrading to dHBP, she improved her LV ejection fraction from 40% to 60% and maintained stable pacing‐sensing parameters over‐time. We here provide a review of existing literature on the topic.
Utility of the Novel Auto + A3 Threshold Function in Maintaining Atrioventricular Synchrony
Authors: Ohinata Ryo , Inoue Naoya , Morikawa Shuji 
Published: December 2024

ABSTRACTIntroductionThe VDD‐leadless pacemaker aims to maintain high atrioventricular (AV) synchrony, but proper sensing setup is crucial.Methods and ResultsThis case was an elderly woman with an AV block who received a dual‐chamber pacemaker. Due to ventricular pacing failure, a Micra AV2 was implanted. However, postimplantation, high sinus rate, and frequent premature ventricular contractions were noted. Therefore, the auto + A3 threshold function was used in the atrial‐sensing setup. A few days later, the MAM test confirmed good AV synchrony.ConclusionThe auto + A3 threshold function equipped in the Micra AV2 may offer to maintain high AV synchrony.