bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of Xpert MTB/RIF for the Identification of TB and Drug Resistance Among Smear-Negative and Re-Treatment Cases in Rural Areas of Ethiopia
Authors: Worku Mesfin , Agonafir Mulualem , Yassin Mubarek A. , Yassin Mohammed A. , Datiko Daniel G. , Theobald Sally , Cuevas Luis E. 
Published: July 2019

Introduction:
Tuberculosis (TB) remains a leading infectious cause of morbidity and mortality worldwide. A key contributor to this burden is poor diagnosis as only 60% of new pulmonary tuberculosis (TB) cases in Africa are ever detected. Therefore, this study aimed to assess the feasibility of Xpert MTB/RIF test implementation in the region, and the performance of the assay to increase case detection on the selected rural health care setting.

Objective:
To assess the feasibility of Xpert MTB/RIF test implementation in the rural health care setting in Southern Ethiopia.

Methods:
Two Xpert MTB/RIF machines were brought in 2012 through TB REACH project. It was placed at Yirgalem hospital and at Aletawondo health centre. The instruments were installed after formal training was provided to laboratory technologists for three days. We collected sputum sample from participants who repeatedly had negative smear microscopy and those who had not responded to first-line anti-TB drugs.

Result:
Of the total participants tested, 1828 have valid result (MTB-, MTB+/RIF-, MTB+/RIF+, MTB+/RIF Indeterminate). From the participants with valid results, 217 (11.9%) were Xpert-positive of which were 165 (9.0%) RIF-negative, 6 (0.3%) RIF-indeterminate and 46 (2.5%) RIF-positive. Among TB suspects with previous treatment history and positive by Xpert, RIF resistance was detected in 10 (2.2%). From the new TB suspects with positive Xpert, RIF resistance was detected in 29 (2.7%). All cases identified were linked with TB/MDR-TB treatment centers.

Conclusion:
Xpert provides an additional tool for the diagnosis of TB and drug resistance, with almost 12% of new and retreatment cases obtaining information that is useful for clinical management. To enhance its efficient utilisation, operational challenges should be minimized particularly in relation to availing robust alternative power source.
Prevalence of Chronic Kidney Disease and Its Determinants in Rural Pondicherry, India-A Community Based Cross-Sectional Study
Authors: Kumar P Ravi , Dongre Amol , Muruganandham R. , Deshmukh Pradeep , Rajagovindan D. 
Published: July 2019

Introduction:The burden of CKD is on the rise globally and in India. There are scarce population based studies based in rural industrialized settings in India and elsewhere.Objective:To find out the prevalence and determinants of Chronic Kidney Disease (CKD) among adults in rural Pondicherry, IndiaMethods:It was a community-based cross-sectional study in 13 villages of a Primary Health Centre in rural Pondicherry. A representative sample of 422 adults more than or equal to 50 years of both genders was selected by population proportional to size methods. All the participants were screened by SCORED questionnaire to get the potential cases of CKD. We did serum creatinine, urine examination, blood pressure and anthropometric measurement for the potential cases. CKD was diagnosed by estimation of glomerular filtration rate and presence of protienuria. The data was analyzed using Statistical Package for Social Science version 24. The study was approved by the Institutional Ethics Committee of SMCMCH, Pondicherry.Results:The prevalence of CKD was found to be 24.2% in the study sample of respondents 50 years or more. Most (73.5%) of the CKD cases were at stage 2, Stage 3a had 15% and stage 3b had 2% of the cases. The determinants of CKD were (60-69 years, PR: 2.36,CI:1.36-4.07), poor nutrition(underweight, overweight and obesity)poor nutritional status (underweight:PR: 2.26,CI:1.05-4.89), (overweight:PR: 2.19,CI:1.06-4.52), (obese:PR: 2.13 CI: 1.13-4.01) and presence of at least one chronic co-morbidity(PR:5.85,CI:1.38-24.78). Majority of the patients in the CKD group had minimal proteinuria 87.25%. And 42.15% of the CKD group had no k.w:5 or k.w:6.Conclusion and Recommendation:Considering the higher prevalence of CKD in the study area, targeted screening of adult population should be undertaken as means of early detection, diagnosis, treatment and follow up of at-risk individuals to prevent further progression of CKD. Further research is required to look at the aetiology of CKD.
Evaluation of Fucosylated Haptoglobin as a Diagnostic Biomarker for Hepatocellular Carcinoma in Egypt
Authors: Shalably Nahla M. , Badawi Rehab , Hawash Nehad , Abd-Elsalam Sherief , Elkhalawany Walaa , Hameed Amal Abd EI , Alkassas Galal El-Din 
Published: July 2019

Background:
Most Hepatocellular Carcinomas (HCCs) are diagnosed at an advanced stage. Therefore, there is citation-type an urgent need for better methods of detection and surveillance of patients at risk of HCC. Alpha-fetoprotein (AFP) has a suboptimal diagnostic performance for HCC surveillance, so novel and reliable diagnostic biomarkers are required.

Objective:
The aim of this work is to evaluate fucosylated haptoglobin as a diagnostic biomarker for hepatocellular carcinoma in Egyptian patients.

Materials and Methods:
This case-control study was carried out on 60 patients classified into 3 groups (20 patients on each); group I (HCC group), group II (Cirrhotic group) and group III (Control group). Diagnosis of liver cirrhosis was done by clinical, biochemical and ultrasound (US), whereas the diagnosis of HCC was done by percutaneous biopsy or radiological (by US and triphasic Computerized Tomography (CT) based on the guidelines of the American-Association for the Study of Liver Diseases. HCC stage was clinically defined according to the Barcelona Clinic Liver Cancer (BCLC) staging system. AFP & fucosylated haptoglobin levels were estimated in all groups.

Results:
There was a statistically significant positive correlation between serum fucosylated haptoglobin and tumor size in the HCC group. Serum fucosylated haptoglobin (at 116 U/ ml) showed sensitivity 80%, specificity 65%, positive predictive value 53% and negative predictive value 87% with AUC 0.786. Combination of serum fucosylated haptoglobin and serum AFP at (200 ng/ ml) increased sensitivity that reached 95%.

Conclusion:
Serum fucosylated haptoglobin may serve as a novel diagnostic biomarker for the detection of HCC with higher sensitivity than AFP.
A Facebook R.I.P. Group and Charlotte Eades' Video Diary
Authors: Giaxoglou Korina 
Published: July 2019

The public Facebook R.I.P. group was created in 2012 as a tribute to a young adult aged 18, who died in a car crash just eleven days before his school graduation. His classmates created this Facebook memorial group as a way of extending socially, spatially and temporally the memorials and vigils held in the community immediately after his passing. The different tributes flooding the memorial wall attest to individual moments of remembrance in the here-and-now, recording personal reactions, thoughts and feelings about their loss; in the process, this community of mourners is collectively (re)writing the life of their dead friend as a life worthy of being mourned and celebrated.
Charlotte Eades' Video Diary: this compelling video diary of living with terminal illness renders tellable and visible not only the ‘small’ and ‘big’ battles with cancer, but also the everydayness of life with and despite dying.
Daya Saing Kawin Jantan Mandul Aedes albopictus: Uji Semi Lapang untuk Pengendalian Vektor Demam Berdarah Dengue (DBD)
Authors: Hestiningsih Retno , Kurniawan Muhammad Iqbal , Martini Martini , Kusariana Nissa , Widjanarko Bagoes , Rahayu Ali 
Published: July 2019

Aedes albopictus is the secondary vector that played an important role in the transmission of Dengue Haemorrhagic Fever (DHF). Previous research has examined the exact radiation dose in producing Ae. albopictus sterile males, which is a dose of 60 Gy. Before being applied in the field, a semi-field trial phase is actually needed. This study aims to determine the competitiveness of Ae. albopictus sterile male mating with a semi-field test. This study is a field experiment and used males radiated until becoming a sterile mosquito. Subject mated to fertile female and divided into 3 groups of samples, the control group (10 normal males and 10 normal females), the test group (10 sterile males and 10 normal females) and the combination group (10 normal males, 30 sterile males, and 10 normal females). Treatment was performed with 3 replications. Tested mosquitoes were placed into the special tent of bugs (bugdoom) with condusive environmental conditions of Ae. albopictus mosquitoes. The results of study showed that there was significant differences (p ≤ 0.0001) the level of sterility of eggs. The test insect group produced the highest sterile eggs 100% compared to the other groups. Value of Mating Competitiveness (C index) Male Sterile Mosquito Ae. albopictus of 0.34. This showed that for TSM applications in actual conditions, it is required 3 times of the population size of sterile males from the normal male population in the field.
Deteksi mycobacterium tuberculosis dengan pemeriksaan mikroskopis dan teknik pcr pada penderita tuberkulosis paru di puskesmas darul imarah
Authors: Ramadhan Raisuli , Fitria Eka , Rosdiana Rosdiana 
Published: July 2019

Tuberkulosis merupakan penyakit infeksi menular yang disebabkan oleh Mycobacterium tuberkulosis. Penyakit tuberkulosis masih menjadi masalah utama kesehatan.TB menjadi penyebab kematian kedua terdepan penyakit menular di dunia. Indonesia menduduki peringkat kedua terbanyak setelah India dari enam negara yang menyumbang 60% dari total kejadian TB. Mycobacterium tuberculosis dapat dideteksi pada sputum dengan pemeriksaan mikroskopis, teknik Polymerase Chain Reaction (PCR), dan kultur bakteri. Aceh Besar menjadi urutan ketiga terbanyak penderita TB dan menyumbang 34 % jumlah seluruh kasus baru di Aceh. Penelitian bertujuan untuk mendeteksi Mycobacterium tuberculosis dengan pemeriksaan mikroskopik dan teknik PCR pada penderita tuberkulosis paru yang sudah menjalani pengobatan 2 bulan sampai 6 bulan di Puskesmas Darul Imarah Kabupaten Aceh Besar dengan jumlah sampel minimal 29 pasien TB aktif. Pengumpulan data dilakukan dengan wawancara dan pemeriksaan sputum secara mikroskopis dan teknik PCR. Data dianalisa secara deskriptif. Hasil penelitian didapatkan dari 29 responden hanya 1 sampel yang positif (3,4%) secara mikroskopis, sedangkan pemeriksaan dengan teknik PCR ditemukan 19 sampel yang positif (65,5%). Akurasi deteksi Mycobacterium tuberkulosis dengan teknik PCR sangat tinggi. Mycobacterium tuberkulosis yang tidak terdeteksi dengan pemeriksaan mikroskopis (BTA) dapat dideteksi dengan teknik PCR. Sebaiknya hasil negatif pada pemeriksaan BTA secara mikroskopik dilanjutkan dengan teknik PCR guna menghindari salah diagnosis, mengingat PCR akurasinya tinggi.
Sites dos municípios da Paraíba: análise de vulnerabilidades computacionais
Authors: Sena Alnio Suamy de , Araújo Wagner Junqueira de 
Published: July 2019

O governo eletrônico pode ser caracterizado pela utilização das Tecnologias de Informação e Comunicação pela administração pública, como ferramenta de apoio aos processos de Governo e para entrega de produtos e serviços à sociedade. Contudo as plataformas digitais estão sujeitas a diferentes tipos ameaças eletrônicas, tais ameaças exploram vulnerabilidades no ambiente organizacional e computacional e colocam os ativos de informação em constante risco. Essa pesquisa teve como objetivo analisar possíveis vulnerabilidades computacionais existentes em sites de governo eletrônico dos municípios do Estado da Paraíba. Foram considerados como população da pesquisa os 50 municípios que representam maior participação para a composição do Produto Interno Bruto do Estado da Paraíba (83,4%), deste conjunto foi possível analisar os sites de 40 cidades. A pesquisa se caracterizou como descritiva, com abordagem quantitativa. Para a coleta dos dados, foi utilizado o Nestparker, um software para testes de penetração que tem como função identificar vulnerabilidades em aplicações Web. Como resultado, foram encontradas 822 vulnerabilidades, das quais 15% são Críticas e 15% de Alta Criticidade e 10% foram classificadas como de Média Criticidade. Tais vulnerabilidades tem o potencial de permitir que elementos mal-intencionados causem impactos negativos relevantes à continuidade dos serviços oferecidos nestes sites. Além de identificar as vulnerabilidades foi efetuado analises para indicar como corrigir cada um dos problemas encontrados, o que permite aos gestores públicos tomarem ações que visem minimizar falhas de segurança, bem como no desenvolvimento de uma política de segurança da informação.
Plataforma informacional do ecossistema paulista de inovação: modelo computacional e semântico de apoio à inovação
Authors: Fusco Elvis , Saraiva Coneglian Caio , Mucheroni Marcos Luiz 
Published: July 2019

A inovação como processo é atualmente um dos grandes pilares para que organizações e países possam manter sua sustentabilidade num cenário globalizado de acirrada competição. Uma organização pode desfrutar do resultado de uma inovação por anos, talvez até décadas, considerando que as inovações são capazes de gerar vantagens competitivas, a médio e longo prazo. No Brasil, o poder público ainda é o principal incentivador e financiador de ações de inovação nas organizações, porém, além do governo existe um conjunto de atores que atuam nesse processo, em que se destacam os ambientes de inovação, as universidades, as empresas e as entidades de apoio e fomento. No Estado de São Paulo, o cenário de inovação tem como base o Sistema Paulista de Ambientes de Inovação que institui e regulamenta os Ambientes Formais de Inovação que apoiam as iniciativas de inovação nas organizações. Com o objetivo de ampliar a articulação e apoiar os processos de construção coletiva e colaborativa entre os principais atores de inovação do Estado de São Paulo, esta pesquisa propõe uma Plataforma Informacional do Ecossistema Paulista de Inovação que, a partir de fontes informacionais disponibilizadas pelos atores de inovação e por meio de tecnologias informacionais, semânticas e computacionais, agregue e disponibilize serviços de informação para os atores de inovação. A plataforma informacional utiliza conceitos da Web Semântica e tem como base uma ontologia que representa as informações dos principais atores de inovação do Estado e um conjunto de serviços agregados de informação, formados por agentes computacionais autônomos de extração e serviços de recuperação das informações contidas na plataforma. Por meio dos recursos de extração automática de dados de ambientes informacionais digitais e da disponibilização de serviços informacionais gerados por meio de tecnologias semânticas e computacionais geradas pela plataforma, permite que organizações tenham acesso a insumos informacionais necessários para o fomento a seus projetos de inovação.
Web Semântica e preservação digital: o padrão de metadados PREMIS na proposta do Linked Data
Authors: Arakaki Felipe Augusto , Gonçalez Paula Regina Ventura Amorim , Coneglian Caio Saraiva , Santos Placida Leopoldina Ventura Amorim da Costa , Santarém Segundo José Eduardo 
Published: July 2019

A partir do significante aumento da produção de conteúdos digitais, ações visando a recuperação e a preservação de objetos digitais a longo prazo tornam-se de importância capital em nossos dias, caso contrário, haverá um rompimento no conhecimento devido a perda ou insuficiência na representação das informações disponíveis no ambiente Web. Nesse contexto, a Curadoria Digital se configura como uma área interdisciplinar que gerencia informações com a proposta e o desafio de preservação e transmissão de objetos informacionais, atuando sobre os fatores de risco como: tecnologia obsoleta, fragilidade tecnológica, falta de entendimento sobre o que é uma boa prática digital e recursos inadequados. Nesse cenário, foi feito um recorte sobre conceitos e funções dos metadados para preservação digital. Assim objetiva-se verificar como o padrão de metadados Preservation Metadata: Implementation Strategies (PREMIS) pode ser utilizado para atender as demandas de preservação dos objetos informacionais digitais. Optou-se como procedimento metodológico a revisão da literatura visto que, é uma reflexão sobre a representação da informação tendo como pano de fundo a Web semântica. Como resultado abordou-se a estrutura e as características do padrão metadados PREMIS e sua relação com a Web Semântica.
Desafios para a mediação da retórica da cidadania ao universo das demandas étnicas: exercício investigativo entre os ciganos Calon de Sousa (PB)
Authors: De Medeiros Jéssica Cunha 
Published: July 2019

Partindo das discussões sobre os desafios e as mudanças que foram se instaurando tanto no plano global, como mais restritamente no âmbito do Brasil, com relação ao papel do Estado como instância fundamental para o reconhecimento e atendimento de demandas específicas aos grupos minoritários, vamos trazer a análise para o nosso campo de pesquisa: discutir os ciganos na Paraíba, especialmente, o Rancho dos Calon, localizado no município de Sousa. Ao longo dos últimos 30 anos, assistimos ao processo de articulação entre lideranças Calon e as diversas formas de poder público. O artigo analisa a região de Sousa e como vem se mostrando enquanto um lugar de rota para as famílias ciganas Calon, o que gerou uma relação de fortalecimento de autoridade política local, resultando numa aliança que perdura até hoje. Portanto, entender os processos de mediação em seus diversos níveis entre os Calon de Sousa e o setor público nas suas mais variadas instâncias, com as organizações que se estendem enquanto representação do Estado - tais como agentes governamentais, universidades e agentes comunitários -, abre caminho para começarmos a compreender como estes ciganos incorporam a retórica da cidadania à identidade étnica, como estão organizados social e territorialmente em Sousa e, consequentemente, como diversos grupos e famílias se articulam no Brasil.
Implementasi Application Programming Interface (API) Google Calendar Sebagai Reminder Informasi Kegiatan Pondok Pesantren
Authors: Sulastri Heni , Rahmatulloh Alam , Kurniawan Asep 
Published: July 2019

Masyarakat pada saat ini hampir seluruhnya memiliki akun di dunia maya, terutama akunÂ Googlesebagai salah satu raksasa internet yang menyediakan berbagai macam fasilitas untuk memudahkan penggunanya, dengan fitur yang disediakan sebagaiÂ Application Programming Interface (API) yaitu APIÂ Google Calendarmerupakan salah satu fasiliitas yang digunakan untuk pengingat (reminder) dan penjadwalan kegiatan.Pondok Pesantren memiliki jadwal kegiatan dan informasi yang harus diketahui oleh anggota Pondok Pesantren sebagai pengetahuan dan panduan kegiatan belajar mengajar atau kegiatan lainya yang akan dilakukan. Pondok Pesantren ini jadwal kegiatan dan informasi dipublikasikan dengan cara manual, maka dibutuhkan suatu sistem yang mengelola jadwal kegiatan dan informasi, serta mempublikasikan menggunakanÂ Google Calendaruntuk memberikan pengingatÂ (reminder)atau notifikasi agar tersampaikan kepada anggota Pondok Pesantren. Penelitian ini menggunakan metodologi pengembangan sistemÂ Personal Extreme Programming (PXP)dan hasil dari penelitian ini yaituÂ API Google Calendartelah berhasil diimplementasikan pada apliksi pesantrenÂ reminder, yang dapat mengelola kegiatan dan menyampaikan informasi kegiatan kepada anggota Pondok Pesantren menggunakanÂ Google Calendar.Â
DRONE UNTUK PERCEPATAN PEMETAAN BIDANG TANAH
Authors: Utomo Budi 
Published: July 2019

Abstract Since 2016 the government has accelerated the registration of land systematically complete until in 2025 the whole plot of land in Indonesia registered. In 2018 alone the government is targeting 7 million fields, and 2019 is targeting 9 million. To achieve these targets is required technology that can overcome this. Drone, better known as Unmanned Aerial Vehicle (UAV) or unmanned aircraft technology as a solution for mapping of land with a large target, time and area flexibility desired shooting, and detailed shooting spatial resolution results as well as a relatively cheaper cost than the recording price with satellite. This research uses qualitative method. Data were obtained from the study literature. After the data collected it will be done data analysis with three stages, namely; Reduction, Display, and Conclution. The results of this study shows that the use of drones for the acceleration of land mapping is the right choice because the drone shots have spatial resolution which is so high that it complies with ground mapping rules and the price is cheap. Keywords: drone, mapping, plot of land
Analisis Konektivitas Wilayah di Kota Denpasar
Authors: Shara Aprilia Riszi Indah Dewi 
Published: July 2019

Connectivity analysis is one of the most important things in a regional planning or development. A certain region can be developed properly if the connectivity system of the region is good too. The aim of this research is to identify regional hierarchy, service centers, and inter-regional interactions in each sub-district in Denpasar City. The method used in this research is quantitative method. Data analyzed by using index analysy of centrality, gravitation model, and konig-shimbel. The results showed that based on centrality index and gravity model, West Denpasar District has the highest value compared to the other three districts in Denpasar City. It shows that West Denpasar District is an area with hierarchy I (growth center) Denpasar City. Determination of hinterland-center of Denpasar is based on the availability of facilities in each sub-district. Keywords: connectivity, hierarchy areas, Denpasar City
PERSEPSI MASYARAKAT TERHADAP LINGKUNGAN KANDANG SAPI DI KELURAHAN BENER KECAMATAN TEGALREJO YOGYAKARTA
Authors: Arsanti Vidyana 
Published: July 2019

Abstrak Kegiatan yang berkaitan dengan kandang sapi tentunya tidak lepas dari apa yang disebut dengan limbah. Hal ini juga harus diperhatikan cara limbah ini dikelola dengan baik oleh pengelola kandang sapi dengan tepat manfaat. Data yang digunakan oleh peneliti yaitu Data primer yaitu pengumpulan data dengan kuesioner dan teknik wawancara, Data Sekunder yaitu pengumpulan data dengan dokumentasi dan observasi. Hasil dari penelitian ini (1) Persepsi masyarakat yang tinggal di sekitar lokasi kandang sapi yang dikelola oleh kelompok kandang Tri Andini Rejo memiliki respon netral, (2) Pengelolaan Limbah yang selama ini dilakukan oleh pengelola kandang memiliki pergeseran dari yang semula hanya menumpuk kotoran sapi kemudian di jual, sekarang diproses menjadi pupuk organik yang berkualitas dan bernilai ekonomi tinggi. Pengelolaan Limbah dengan menggunakan teknologi yang maju belum termanfaatkan dengan baik oleh pengelola kandang karena kurangnya kualitas Sumberdaya Manusia. Kata kunci : Kandang Sapi, Pengolahan Limbah, Persepsi Masyarakat