bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aerobic and Resistance Exercise Improves Shoulder Function in Women Who Are Overweight or Obese and Have Breast Cancer: A Randomized Controlled Trial
Authors: Sweeney Frank C , Demark-Wahnefried Wendy , Courneya Kerry S , Sami Nathalie , Lee Kyuwan , Tripathy Debu , Yamada Kimiko , Buchanan Thomas A , Spicer Darcy V , Bernstein Leslie , Mortimer Joanne E , Dieli-Conwright Christina M 
Published: July 2019

Abtract

Background
Adverse upper limb musculoskeletal effects occur after surgical procedures and radiotherapy for breast cancer and can interfere with activities of daily living.

Objective
The objective of this study was to examine the effects of a 16-week exercise intervention on shoulder function in women who are overweight or obese and have breast cancer.

Design
This study was a randomized controlled trial.

Setting
The study was performed at the Division of Biokinesiology and Physical Therapy at the University of Southern California.

Participants
One hundred women with breast cancer were randomly allocated to exercise or usual-care groups. The mean (SD) age of the women was 53.5 (10.4) years, 55% were Hispanic white, and their mean (SD) body mass index was 33.5 (5.5) kg/m2.

Intervention
The 16-week exercise intervention consisted of supervised, progressive, moderate to vigorous aerobic and resistance exercise 3 times per week.

Measurements
Shoulder active range of motion, isometric muscular strength, and patient-reported outcome measures (including Disabilities of the Arm, Shoulder, and Hand and the Penn Shoulder Scale) were assessed at baseline, after the intervention, and at the 3-month follow-up (exercise group only). Differences in mean changes for outcomes were evaluated using mixed-model repeated-measures analysis.

Results
Compared with the usual-care group, the exercise group experienced significant increases in shoulder active range of motion (the mean between-group differences and 95% confidence intervals (CIs) were as follows: shoulder flexion = 36.6° [95% CI = 55.2–20.7°], external rotation at 0° = 23.4° [95% CI = 31.1–12.5°], and external rotation at 90° = 34.3° [95% CI = 45.9–26.2°]), improved upper extremity isometric strength, and improved Disabilities of the Arm, Shoulder, and Hand and Penn Shoulder Scale scores.

Limitations
Limitations include a lack of masking of assessors after the intervention, an attention control group, and statistical robustness (shoulder function was a secondary end point).

Conclusions
A 16-week exercise intervention effectively improved shoulder function following breast cancer treatment in women who were overweight or obese, who were ethnically diverse, and who had breast cancer.
What Is the Effect of Health Coaching Delivered by Physical Therapists? A Systematic Review of Randomized Controlled Trials
Authors: Rethorn Zachary D , Pettitt Cherie D 
Published: July 2019

Abstract

Background
Health coaching has emerged as an intervention for improving health behaviors. Given the recent increased integration of health coaching into physical therapist practice, there has been a subsequent rise in research examining the effects of health coaching provided by physical therapists. However, there is a lack of literature summarizing the effectiveness of health coaching delivered by physical therapists in changing patient health behaviors.

Purpose
The purpose of this study was to systematically review the effects of health coaching delivered by physical therapists on promoting participant health behaviors.

Data Sources
Cochrane, CINAHL, MEDLINE, PEDro, PsycINFO, and Web of Science databases were searched from inception to May 26, 2018, to identify randomized controlled trials examining the effects of health coaching delivered by physical therapists.

Study Selection
Two reviewers independently screened titles, abstracts, and full texts according to inclusion and exclusion criteria to determine study eligibility.

Data Extraction
Methodological quality was assessed using Physiotherapy Evidence Database (PEDro) scores. Risk of bias was assessed using the Cochrane Collaboration risk-of-bias assessment tool. Data were extracted using a standardized data extraction form describing study methods, design, and outcomes.

Data Synthesis
Eleven trials met the inclusion criteria for this study. Health coaching produced positive effects on physical activity (6 studies) as well as physiological and psychological secondary outcomes.

Limitations
The inclusion of only 11 randomized controlled trials in this review could limit the generalizability of the findings. The heterogeneity of the findings precluded the performance of a meta-analysis.

Conclusions
Research on the effectiveness of health coaching delivered by physical therapists on health behavior outcomes is mixed. Data indicate statistically significant changes in some health behavior, physiological, and psychological outcomes.
Frequency and distribution of various rheumatic disorders associated with checkpoint inhibitor therapy
Authors: Abdel-Wahab Noha , Suarez-Almazor Maria E 
Published: July 2019

AbstractImmune checkpoint inhibitors have advanced the treatment paradigm of various cancers, achieving remarkable survival benefits. However, a myriad of immune-related adverse events (irAE) has been recognized in almost every organ system, presumably because of persistent immune system activation. Rheumatic symptoms such as arthralgia or myalgia are very common. More specific irAE are increasingly being reported. The most frequent ones are inflammatory arthritis, polymyalgia-like syndromes, myositis and sicca manifestations. These rheumatic irAE can develop in ∼5–10% of patients treated with immune checkpoint inhibitors, although true incidence rates cannot be estimated given the lack of prospective cohort studies, and likely underreporting of rheumatic irAE in oncology trials. In this review, we will provide a summary of the epidemiologic data reported for these rheumatic irAE, until more robust prospective longitudinal studies become available to further define the true incidence rate of rheumatic irAE in patients receiving these novel cancer therapies.
A scent of romance: human putative pheromone affects men’s sexual cognition
Authors: Oren Chen , Peled-Avron Leehe , Shamay-Tsoory Simone G 
Published: July 2019

Abstract
Previous studies suggest that the putative human pheromone estratetraenol affects several systems underlying human functioning and appears to activate neural systems that are known to affect sexual behavior. In this study, we investigated whether exposure to estratetraenol affects men’s social cognition abilities. In the first experiment, men performed the Interpersonal Perception task while being exposed to estratetraenol and to a control solution. Men performed the task with better accuracy while being exposed to estratetraenol. This improvement was evident especially in the Intimacy category where participants evaluated romantic relationships. In a second experiment, we exposed a different sample of men to estratetraenol and to a control solution while performing a task that implicitly measured their emotional reaction to photos depicting two humans either romantically touching or not, with a control condition of two inanimate objects either touching or not. We found that the participants’ emotional reaction to touch was stronger under exposure to estratetraenol. Together, these results suggest that exposure to estratetraenol may trigger a change in men’s social cognition, especially in sexually related situations.
Universal Basic Income, Poverty, and Social Justice: A Moral and Economic Imperative for Social Workers
Authors: Hamilton Leah , Martin-West Stacia 
Published: July 2019

Abstract
Modern technology threatens to dramatically alter the U.S. labor economy, but the crumbling social safety net may be insufficient for affected workers. Some advocates propose to address these converging problems through universal basic income (UBI). Authors conducted a preliminary review of social work perspectives on the topic of UBI. They found very little relevant literature, especially among American scholars. Existent social work literature frames UBI as an alternative to the neoliberal welfare state and mass unemployment. Social workers also contribute a critical social justice orientation to UBI scholarship in other disciplines. Grounded in the NASW Code of Ethics, authors argue that it is imperative for American social workers to seriously consider UBI as an answer to growing inequality and the unique expertise that social workers offer as allies of marginalized populations.
Consumer Activism for Social Change
Authors: Lightfoot Elizabeth Bradford 
Published: July 2019

Abstract
Consumer activism, or activism taken by consumers through participating in the market such as through boycotts or ethical shopping, is the most common form of political action in the United States aside from voting. Although consumer activism was a popular macro practice social work intervention by social work pioneers and has been an important part of many social change movements internationally, it is rarely discussed formally in the field of social work in the United States today. This article provides an overview of consumer activism as a social work intervention, describes historical and 21st century examples of consumer activism, and discusses the effectiveness of consumer activism. The article ends with a discussion of the strengths and challenges of consumer activism for social workers who engage in it either professionally or personally.
Decline in Racial Disparities in Postmastectomy Breast Reconstruction: A Surveillance, Epidemiology, and End Results Analysis from 1998 to 2014
Authors: Sergesketter Amanda R. , Thomas Samantha M. , Lane Whitney O. , Orr Jonah P. , Shammas Ronnie L. , Fayanju Oluwadamilola M. , Greenup Rachel A. , Hollenbeck Scott T. 
Published: July 2019

Background:
Despite increasing emphasis on reducing racial disparities in breast cancer care in the United States, it remains unknown whether access to breast reconstruction has improved over time. The authors characterized contemporary patterns of breast reconstruction by race and ethnicity.

Methods:
The Surveillance, Epidemiology, and End Results database was used to identify women undergoing mastectomy for stage 0 to III breast cancer from 1998 to 2014. Multivariable logistic regression was used to estimate the association of demographic factors with likelihood of postmastectomy reconstruction. Multivariable logistic regression was used to predict reconstruction subtype. Patients undergoing reconstruction were grouped by diagnosis year to assess change in the population over time by race and ethnicity.

Results:
Of 346,418 patients, 21.8 percent underwent immediate reconstruction. Non-Hispanic black race (OR, 0.71) and Hispanic ethnicity (OR, 0.63) were associated with a decreased likelihood of reconstruction (all p < 0.001). Race was predictive of reconstruction type, with non-Hispanic black (OR, 1.52) and Hispanic women (OR, 1.22) more likely to undergo autologous versus implant-based reconstruction (p < 0.001). Although rates of reconstruction increased over time across all races, non-Hispanic black and Hispanic patients had a higher adjusted per-year increase in rate of reconstruction compared with non-Hispanic white patients (interaction p < 0.001).

Conclusions:
Rates of postmastectomy reconstruction have increased more quickly over time for minority women compared with white women, suggesting that racial disparities in breast reconstruction may be improving. However, race continues to be associated with differences in types and rates of reconstruction. Further research is necessary to continue to improve access to breast reconstruction in the United States.

CLINICAL QUESTION/LEVEL OF EVIDENCE:
Risk, III.
Nasal Analysis: Considerations for Ethnic Variation
Authors: Villanueva Nathaniel L. , Afrooz Paul N. , Carboy Jourdan A. , Rohrich Rod J. 
Published: July 2019

Summary:
As the United States continues to be more ethnically and racially diverse, it is important for the rhinoplasty surgeon to have an appreciation and understanding of nasal variations that exist to plan for and execute ethnically congruent results. The nasal analysis is a critical component of the patient evaluation, which has been used as a tool by surgeons to identify deviations from anatomical norms or canons. In this article, the authors describe common nasal anatomical variations that exist between ethnic groups as a guide for nasal analysis. Understanding these variations will facilitate and help define important cultural aesthetics, which can be used to plan for rhinoplasties in a diverse patient population.
Stacked Lateral Thigh Perforator Flap as a Novel Option for Autologous Breast Reconstruction
Authors: Tessler Oren , Guste John , Bartow Matthew J. , Torabi Radbeh , Gimenez Alejandro , Patel Shukan B. , Matatov Tim , Torabi Rozbeh , St. Hilaire Hugo , Allen Bob 
Published: July 2019

Background:
Autologous breast reconstruction using perforator flaps offers excellent outcomes, minimizes donor-site morbidity, and allows for precise donor-site selection. The deep inferior epigastric artery perforator, profunda artery perforator, and gluteal artery perforator flaps along with the stacked flap technique are the most common options. This study reports the first series of the stacked lateral thigh perforator flap.

Methods:
A retrospective review of all stacked lateral thigh perforator flaps done by a single group of surgeons was performed. Demographics, flap weights, complications, indications, and surgical technique were tabulated for each patient.

Results:
Eight female patients with a history of breast cancer underwent delayed unilateral breast reconstruction with stacked lateral thigh perforator flaps for a total of 16 flaps. Mean patient age, body mass index, flap weight, and stacked flap weight were 47.3 years, 26.2 kg/m2, 333.1 g, and 666.1 g, respectively. Microsurgical revascularization was completed in anterograde and retrograde fashion to the internal mammary vasculature. Flap survival was 100 percent and one subsequent flap revision was performed. Two patients developed a seroma at the donor site. Indications included insufficient abdominal tissue, prominent lateral thigh lipodystrophy, prior abdominal surgery, and failed prior abdominally based autologous reconstruction.

Conclusions:
This series demonstrates that the lateral thigh perforator flap is a reliable and effective option for a stacked breast reconstruction. Its ease of harvest (stemming from reliable anatomy), straightforward dissection, and intraoperative positioning make it an appealing flap option. The stacked lateral thigh perforator flap allows the reconstructive surgeon to tailor breast reconstruction to the patient, focusing on body habitus and minimizing morbidity.

CLINICAL QUESTION/LEVEL OF EVIDENCE:
Therapeutic, IV.
Non-Canonical Regulation of Phosphatidylserine Metabolism by a Phosphatidylinositol Transfer Protein and a Phosphatidylinositol 4-OH Kinase
Authors: Wang Yaxi , Yuan Peihua , Tripathi Ashutosh , Rodriguez Martin , Lönnfors Max , Eisenberg-Bord Michal , Schuldiner Maya , Bankaitis Vytas A. 
Published: July 2019

ABSTRACTThe phosphatidylserine (PtdSer) decarboxylase Psd2 is proposed to engage in an endoplasmic reticulum (ER)-Golgi/endosome membrane contact site (MCS) that facilitates phosphatidylserine decarboxylation to phosphatidylethanomaine (PtdEtn) inSaccharomyces cerevisiae. While this MCS is envisioned to consist of Psd2, the Sec14-like phosphatidylinositol transfer protein (PITP) Sfh4, the Stt4 phosphatidylinositol (PtdIns) 4-OH kinase, the Scs2 tether, and at least one other uncharacterized protein, functional data that address key foundations of this model are sparse. We now report that Psd2, Sfh4 and Stt4 are the only components individually required for biologically sufficient Psd2-dependent PtdEtn production. Surprisingly, neither the PtdIns-transfer activity of Sfh4 nor its capacity to activate Stt4 is required to stimulate the Psd2 pathway. Instead, Sfh4 activates the Psd2 pathway via a specific Sfh4-Psd2 physical interaction. Whereas the data indicate an Sfh4-independent association of Stt4 with Psd2 as well, we find Stt4 also regulates Psd2 activity indirectly by influencing the PtdSer pool accessible to Psd2 for decarboxylation. These collective results demonstrate that the proposed ER-Golgi/endosomal MCS model fails to provide an accurate description of the Psd2 system in yeast, and provide an example where the biological function of a Sec14-like PITP is uncoupled from its ‘canonical’ activity as a PtdIns transfer protein.
Comparison of human population receptive field estimates between scanners and the effect of temporal filtering
Authors: Morgan Catherine , Schwarzkopf D Samuel 
Published: July 2019

AbstractPopulation receptive field (pRF) analysis with functional magnetic resonance imaging (fMRI) is an increasingly popular method for mapping visual field representations and estimating the spatial selectivity of voxels in human visual cortex. However, the multitude of experimental setups and processing methods used makes comparisons of results between studies difficult. Here, we show that pRF maps acquired in the same three individuals using comparable scanning parameters on a 1.5 and a 3 Tesla scanner located in two different countries are very similar. As expected, the signal-to-noise ratio for the 3 Tesla data was superior; critically, however, estimates of pRF size and cortical magnification did not reveal any systematic differences between the sites. Moreover, we tested the effect of low-pass filtering of the time series on pRF estimates. Unsurprisingly, filtering enhanced goodness-of-fit, presumably by removing high-frequency noise. However, there was no substantial increase in the number of voxels containing meaningful retinotopic signals after low-pass filtering. Importantly, filtering also increased estimates of pRF size in the early visual areas which could substantially skew interpretations of spatial tuning properties. Our results therefore suggest that pRF estimates are generally comparable between scanners of different field strengths, but temporal filtering should be used with caution.PrecisPopulation Receptive Field mapping performed with similar protocols at two different sites, a 1.5T MRI scanner in London, and a 3T scanner in Auckland, yielded comparable results. Temporal filtering of the fMRI time course increased concordance of modelled pRFs, but introduced a bias in pRF size.
RPS28B mRNA acts as a scaffold promoting cis-translational interaction of proteins driving P-body assembly
Authors: Fernandes Nikita , Buchan J. Ross 
Published: July 2019

AbstractP-bodies (PBs) are cytoplasmic mRNA-protein (mRNP) granules conserved throughout eukaryotes which are implicated in the repression, storage and degradation of mRNAs. PB assembly is driven in part by proteins with self-interacting and low-complexity protein domains. Non-translating mRNA is also required for PB assembly, however no studies to date have explored whether particular mRNA transcripts are more critical than others in facilitating PB assembly. A previous genome-wide microscopy screen in yeast revealed that rps28bΔ (Ribosomal protein subunit-28B) mutants do not form PBs under normal growth conditions. Here, we demonstrate that the RPS28B 3’UTR is important for PB assembly, consistent with the fact that this is a known binding site for the PB assembly protein Edc3. However, expression of the RPS28B 3’UTR in isolation is insufficient to drive normal PB assembly. Intriguingly, chimeric mRNA studies revealed that Rps28 protein, translated in cis from an mRNA bearing the RPS28B 3’UTR, physically interacts more strongly with Edc3 than Rps28 protein synthesized in trans. This Edc3-Rps28 interaction in turn also facilitates PB assembly. In summary, our work indicates that PB assembly may be preferentially nucleated by specific RNA “scaffolds”, which may be a common theme in RNP granule assembly. Furthermore, this is the first description in yeast to our knowledge of a cis-translated protein interacting with another protein in the 3’UTR of the mRNA which encoded it, which in turn has functional consequences for assembly of cellular structures.
Stigma on mental illness in the Arab world: beyond the socio-cultural barriers
Authors: Merhej Rita 
Published: July 2019

PurposeResearch on mental illness stigma in the Arab world has traditionally focused on socio-cultural barriers that deprive persons with mental illness from their fundamental human right for privacy and informed consent. The purpose of this paper is to address the question whether or not mental health legislations in a number of Arab countries effectively safeguard the human rights of people with mental illness and protect them from stigmatizing and discriminatory practices.Design/methodology/approachA qualitative review of literature was performed over two rounds of search, targeting published research on mental illness stigma in the Arab world from year 2000 until now and existing national mental health legislations in the Arab world, using English and Arabic databases.FindingsThe review reveals that beyond society and culture, persistence of mental illness stigma in the Arab world may be explained by absent or inefficient monitoring mechanisms of mental health legislations and policies within the health-care setting. Although integration of mental health services into the primary health care system is being gradually implemented as a step toward de-stigmatization of mental illness, more remains to be done to change the stigmatizing behavior of the health personnel toward mental illness.Originality/valueMental health authorities in the Arab world need to be more aware of the public perceptions explaining people’s fear and reluctance to seek mental health care, so as to ensure that the control and monitoring mechanisms at both the primary and mental health care levels foster a human rights, culturally competent, patient-friendly and non-stigmatizing model of mental health care.
The added value of a new interviewing tool for the selection of candidates for the teaching profession
Authors: Levy-Feldman Irit , Libman Zipora 
Published: July 2019

Purpose
An interview is one of the most widely used tools in the admission of candidates for an academic study, particularly in the applied professions. The purpose of this paper is to present a study that assesses the quality of a new interview tool for the selection of teacher-training candidates, in order to find out its added value over other selection tools in use and to justify the effort invested in it.

Design/methodology/approach
The study was longitudinal and was conducted over the course of a three-year period. The study population consisted of all the college’s undergraduate students that were candidates for the teaching profession. The information was processed quantitatively using descriptive as well as inferential statistics while addressing diverse comparisons.

Findings
The main findings indicate a high quality of the new tool. The usage of the tool improved the selection procedure of qualified candidates, especially borderline candidates who would be rejected if using only the matriculation and the psychometric admission tools. A logistic regression model revealed the admission new interview tool to be the sole statistically significant predictor of enrollment in the college. The study reported the interview score to be the sole statistically significant predictive factor in the model that forecasts student field-practice grades, particularly in their first year of study.

Originality/value
This information further corroborates that a good interview tool allows a more in-depth and well-based discussion about worthy candidates who do not meet the strict grade admission requirements. This invites discussion regarding the critical place of the interview in selection of candidates, especially in applied professions.