bluuebunny/crossref_metadata_2025_split huggingface dataset:
REASSESSING FRONTLINE MEDICAL PRACTITIONERS OF THE BRITISH CIVIL WARS IN THE CONTEXT OF THE SEVENTEENTH-CENTURY MEDICAL WORLD
Authors: PELLS ISMINI 
Published: June 2018

AbstractMedical provision in Civil War armies has generally suffered a poor reputation. Medical matters have been excluded from assessments of how far Civil War armies confirm evidence of the so-called ‘Military Revolution’, whilst Harold Cook argued that it was not until after the Glorious Revolution that the medical infrastructure of the armed forces was brought in line with continental practices, particularly those of the Dutch army. Despite the recent rehabilitation of early modern practitioners elsewhere, frontline military practitioners continue to be dismissed as uneducated, unskilful and incompetent. This is largely due to the lack of a fresh perspective since C. H. Firth publishedCromwell's Armyin 1902. This article argues that the English were well aware of current medical practice in European armies and endeavoured to implement similar procedures during the Civil Wars. Indeed, almost all the developments identified by Cook for the later seventeenth century can be found in Civil War armies. Whilst failures may have occurred, most of these can be attributed to administrative and financial miscarriages, rather than ignorance of contemporary medical developments. Moreover, there is little to suggest that medics mobilized for Civil War armies were any less capable than those who practised civilian medicine in this period.
At the heart of programming: the role of micro-RNAs
Authors: Siddeek B. , Mauduit C. , Yzydorczyk C. , Benahmed M. , Simeoni U. 
Published: June 2018

AbstractEpidemiological and experimental observations tend to prove that environment, lifestyle or nutritional challenges influence heart functions together with genetic factors. Furthermore, when occurring during sensitive windows of heart development, these environmental challenges can induce an ‘altered programming’ of heart development and shape the future heart disease risk. In the etiology of heart diseases driven by environmental challenges, epigenetics has been highlighted as an underlying mechanism, constituting a bridge between environment and heart health. In particular, micro-RNAs which are involved in each step of heart development and functions seem to play a crucial role in the unfavorable programming of heart diseases. This review describes the latest advances in micro-RNA research in heart diseases driven by early exposure to challenges and discusses the use of micro-RNAs as potential targets in the reversal of the pathophysiology.
Energy transport pathway in proteins: Insights from non-equilibrium molecular dynamics with elastic network model
Authors: Wang Wei Bu , Liang Yu , Zhang Jing , Wu Yi Dong , Du Jian Jun , Li Qi Ming , Zhu Jian Zhuo , Su Ji Guo 
Published: June 2018

AbstractIntra-molecular energy transport between distant functional sites plays important roles in allosterically regulating the biochemical activity of proteins. How to identify the specific intra-molecular signaling pathway from protein tertiary structure remains a challenging problem. In the present work, a non-equilibrium dynamics method based on the elastic network model (ENM) was proposed to simulate the energy propagation process and identify the specific signaling pathways within proteins. In this method, a given residue was perturbed and the propagation of energy was simulated by non-equilibrium dynamics in the normal modes space of ENM. After that, the simulation results were transformed from the normal modes space to the Cartesian coordinate space to identify the intra-protein energy transduction pathways. The proposed method was applied to myosin and the third PDZ domain (PDZ3) of PSD-95 as case studies. For myosin, two signaling pathways were identified, which mediate the energy transductions form the nucleotide binding site to the 50 kDa cleft and the converter subdomain, respectively. For PDZ3, one specific signaling pathway was identified, through which the intra-protein energy was transduced from ligand binding site to the distant opposite side of the protein. It is also found that comparing with the commonly used cross-correlation analysis method, the proposed method can identify the anisotropic energy transduction pathways more effectively.
Assessment of Fv/Fm absorbed by wheat canopies employing in-situ hyperspectral vegetation indexes
Authors: Tan Chang-Wei , Wang Dun-Liang , Zhou Jian , Du Ying , Luo Ming , Zhang Yong-Jian , Guo Wen-Shan 
Published: June 2018

AbstractChlorophyll fluorescence parameter of Fv/Fm, as an important index for evaluating crop yields and biomass, is key to guide crop management. However, the shortage of good hyperspectral data can hinder the accurate assessment of wheat Fv/Fm. In this research, the relationships between wheat canopy Fv/Fm and in-situ hyperspectral vegetation indexes were explored to develop a strategy for accurate Fv/Fm assessment. Fv/Fm had the highest coefficients with normalized pigments chlorophyll ratio index (NPCI) and the medium terrestrial chlorophyll index (MTCI). Both NPCI and MTCI were increased with the increase in Fv/Fm. However, NPCI value ceased to increase as Fv/Fm reached 0.61. MTCI had a descending trend when Fv/Fm value was higher than 0.61. A piecewise Fv/Fm assessment model with NPCI and MTCI regression variables was established when Fv/Fm value was ≤0.61 and >0.61, respectively. The model increased the accuracy of assessment by up to 16% as compared with the Fv/Fm assessment model based on a single vegetation index. Our study indicated that it was feasible to apply NPCI and MTCI to assess wheat Fv/Fm and to establish a piecewise Fv/Fm assessment model that can overcome the limitations from vegetation index saturation under high Fv/Fm value.
Determining the Rotational Orientation of Directional Deep Brain Stimulation Leads Employing Flat-Panel Computed Tomography
Authors: Hunsche Stefan , Neudorfer Clemens , Majdoub Faycal El , Maarouf Mohammad , Sauner Dieter 
Published: June 2018

Abstract

BACKGROUND
Directional deep brain stimulation (DBS) constitutes an emerging technology that allows selective stimulation of target structures via partitioned electrode contacts. In order to effectively perform target-tailored stimulation, knowledge of the rotational orientation of the segmented leads is imperative.

OBJECTIVE
To develop a universally applicable and reliable method for determination of lead orientation angles in DBS using flat-panel computed tomography (fpCT).

METHODS
A binary template of directional leads DB-2202-30 (Boston Scientific, Natick, Massachusetts) and 6170 (Abbott, Plano, Texas) was imported into the 2-dimensional raw data set of a conventional fpCT scan. The template was aligned with and manually rotated around the predetermined lead trajectory. The overall orientation of the segmented lead can be deduced by transferring position and orientation of the lead orientation marker into the 3-dimensional volume. Accuracy of the method was investigated by two raters in a phantom study.

RESULTS
Accuracy were 5.4° ± 4.1° (range: 0.4°-11.9°) for rater 1 and 5.2° ± 3.0° (range: 0.3°-10.2°) for rater 2, when investigating DB-2202-30. For 6170 observed deviations were 2.5° ± 1.7° (range: 0.2°-5.2°) and 4.3° ± 3.6° (range: 0.2°-11.2°) for raters 1 and 2, respectively.

CONCLUSION
fpCT imaging constitutes a precise and accurate means to determine the rotational orientation of directional leads. The approach is universally transferable to different electrode designs as the template can easily be adjusted to the electrodes’ specific measures. The approach is independent from polar implantation angles owing to fpCT- and methodological features.
Moderating influence of advisor personality on the association between financial advice and investor stock trading behavior
Authors: Tauni Muhammad Zubair , Majeed Muhammad Ansar , Mirza Sultan Sikandar , Yousaf Salman , Jebran Khalil 
Published: June 2018

PurposeThe purpose of this paper is to investigate the role of financial advice on investor trading behavior by analyzing the influence of advisor personality.Design/methodology/approachThe study utilized the Big Five personality framework from Costa and McCrae (1992) to measure personality traits of advisors and examined the data collected from 314 stock investor–advisor dyads. Personality traits of advisors were measured by the NEO-Five Factor Inventory (Costa and McCrae, 1989). Confirmatory factor analysis was conducted to assess the fitness of the Big Five model. We followed two-stage least square method for estimating endogenous covariate by employing instrumental variable analysis. Probit model was used to evaluate the moderating influence of advisor personality traits on the association between the usage of financial advice and trading behavior.FindingsThe authors found that financial advice positively impacts investors’ stock trading frequency. The authors also provide empirical evidence that financial advice is more likely to increase trading frequency when advisor personality tends to be openness, conscientiousness and agreeableness. On the other hand, information acquired from financial advisors causes fewer adjustments in investors’ portfolios when the personality of advisors is likely to be extraverted and neurotic.Research limitations/implicationsThe theoretical model in our study seeks to explain that a psychological factor, namely, advisor personality, influences the way an investor interprets information signals from financial advice, which, in turn, influences the investor’s decision to trade in securities.Practical implicationsThis research suggests that characteristics of advisors other than those of investors can be of relevance for policy makers in their attempts to improve their business in the financial services industry.Originality/valueSurvey-based studies in finance are lacking. This study adds to the existing literature of behavioral finance that accounts for the observed variations in investors’ financial decision making explained by psychological factors. No previous study has been conducted so far exploring variations in the impact of financial advice on investors’ stock trading behavior by the Big Five advisor personality, and this paper strives to fill this research gap in Chinese stock market.
A metabolomic study of Antarctic krill (Euphausia superba) raises a warning about Antarctic pollution
Authors: Zhang Fengying , Zhao Ming , Ma Chunyan , Wang Lumin , Feng Chunlei , Li Lingzhi , Ma Lingbo 
Published: June 2018

Abstract
Antarctic krill (Euphausia superba) is one of the most successful species on Earth and serves as the largest potential protein bank for both Antarctic animals and humans. Research on this species is of great value for exploitation of Antarctic biotic resources. In this study, the metabolomics of E. superba were investigated using the GC-MS method. A total of 293 compounds were initially identified; these compounds could be divided into several classes, including amino acids, sugars and polyols, metabolic intermediates, small molecules and other metabolites. However, a serious problem was that both 2-hydroxybiphenyl and dioctyl phthalate were also detected in these krill tissues. Moreover, some intermediates of pesticides and medicinal or chemical compound products were found in krill tissue as well. This is the first survey to investigate the occurrence of chemical contamination in metabolites of Antarctic krill. These findings suggest that international contracts or policies should be developed to protect the pristine ocean.
The effects of rotation on radiological parameters in the spine
Authors: Wong Christian , Hall Johanna , Gosvig Kasper 
Published: June 2018

Background Vertebral rotation in straight spines or in spines with small scoliosis may potentially affect measurement of radiological parameters in both the frontal and sagittal plane. This is important, since it could lead to potential misdiagnosis of scoliosis and other clinical consequences, and until now, this has not been examined. Purpose To examine the effect of axial vertebral rotation of the spine on measurement of common radiological parameters. Material and Methods Reconstructions from computed tomography scans of 40 consecutive included and anonymized patients with straight spines or small scoliosis. Fourteen sagittal and coronal reconstructions covering the whole pelvis and spine were executed. Radiographic parameters in both the frontal and sagittal plane were measured blinded and separately by three doctors. These parameters were evaluated for inter-rater reliability using intraclass correlation coefficient and mixed model analysis for the effects of rotation. The parameters were also analyzed sub-stratified according to “Lenke's classification” and 15 sub-categories of thoracic and lumbar Cobb's angle (CA). Results Vertebral rotation in general does not have any significant effects in both the frontal and sagittal plane. However, there are significant effects on CA and spinopelvic radiologic parameters in extreme rotation or for larger scoliosis. Inter-rater reliability was very good to good. Conclusion In conclusion, axial spinal rotation does not influence common radiological parameters in the frontal and sagittal plane, except in cases of extreme rotation or large scoliosis for selected parameters; thus, this does not lead to potential misinterpretation in scoliosis diagnosis, treatment, or research.
BLADDER CANCER AND DEBATE ON TRIMODAL THERAPY (TMT) FOR BLADDER PRESERVATION
Authors: Melo Antonio Marlos Duarte de , Sampaio José Angelo Araújo , Neves Ana Beatriz Callou Sampaio , Neves Isabella Callou Sampaio , Parente Lucas Leimig Telles , Telles Maria Valéria Leimig , Silva Mikael Vieira da 
Published: June 2018

Abstract: Bladder Cancer is one of the most common types of malignant neoplasms that affects both men and women. The surgery considered standard for the treatment of invasive tumor is Radical Cystectomy, which causes undesirable morbidity in the postoperative period on affected patients. Radical Transurethral Resection (TRU), associated with Chemotherapy and Radiotherapy, together form the Trimodal Therapy (TTM), which can demonstrate satisfactory results in the approach of the patient with invasive tumor with lower morbidity and well-timed survival rate, in a short time. Keywords: Bladder Cancer; Radical Cystectomy; Transurethral Resection; Trimodal Therapy.
El café científico: Una experiencia áulica con estudiantes del Profesorado de Biología.
Authors: Gomez Silbia Marisa 
Published: June 2018

En el presente trabajo se desarrolla el diseño y puesta en práctica de una estrategia didáctica diseñada para la unidad curricular “Evolución”, del profesorado de Biología. El enfoque utilizado corresponde al modelo TPACK (Technological Pedagogical Content Knowledge), que considera las tres fuentes del conocimiento: la disciplinar, la pedagógica y la tecnológica, enfatizando en las nuevas formas de conocimiento que se generan en la intersección de unos saberes con otros.La propuesta se basó en la simulación de un café científico donde los estudiantes a través de juegos de roles representaron a distintas personalidades de la ciencia relacionadas con las Teorías del Origen de la vida. Esta estrategia didáctica apuntó a un aprendizaje cooperativo, al desarrollo de la creatividad, a la actitud crítica ante el conocimiento y la información, al desarrollo de competencias propias de la disciplina y a la formación de una actitud positiva frente a nuevas formas de aprender.Si bien esta experiencia pedagógica demandó otros tiempos y otras formas de planificar, de organización pedagógica del aula, otras formas de vincularse entre docentes, estudiantes y conocimiento y por lo tanto de aprender, esto devino en una mayor motivación e interés de los estudiantes, generándose entornos propicios para la expresión y la creatividad.
Percepción del alumnado sobre la implementación de una propuesta b-learning en el ámbito de la enseñanza de Parasitología y Micología.
Authors: Pawluk Diana Beatriz , Fabro Ana Patricia 
Published: June 2018

En la actualidad, el cursado de la Sección Parasitología y Micología de Práctica Profesional de la carrera de Bioquímica (Facultad de Bioquímica y Ciencias Biológicas, UNL), se desarrolla mediante una modalidad b-learning, basada en la enseñanza presencial y complementada mediante la inclusión de Tecnologías de la Información y la Comunicación (TICs) y la utilización de diversos recursos en el entorno virtual de la UNL. La propuesta de este trabajo consistió en reflexionar sobre el grado de reconocimiento (por parte de los alumnos) de la complementariedad de los recursos didácticos ofrecidos para el desarrollo de las actividades en dicha Sección. Se diseñó una experiencia de investigación cuali-cuantitativa, entre el 2do cuatrimestre de 2013 y el 2do cuatrimestre del 2016. Se suministró a 149 alumnos, al final del cursado de la Sección, una encuesta que constaba de siete items que promovían respuestas abiertas sobre la temática a investigar. Los resultados obtenidos fueron: 50.4% destacó la facilidad de acceso al material de estudio actualizado desde cualquier lugar; 40.5% respondió que el entorno virtual permite una mayor interacción, docentes-alumnos, y, alumnos-alumnos; el 76% consideró a los recursos como muy completos y organizados en distintos formatos; en cuanto a la cantidad de información brindada, el 8.4% calificó como excelente, 49% muy buena, 28.2% buena; en calidad el 17.6% respondió como excelente, 54.2% muy buena y 28.2% buena; los aspectos que debe mejorar la propuesta: 35.1 % mencionó la inclusión de novedades, videos, información en general, horarios de foros, chats ; 12.2% mejorar la interacción alumno-docente; 90.1% respondió que observan ventajas consideradas como fortalezas de la propuesta y el 71.8% respondió que existen algunas debilidades al comparar el uso de TICs y el Entorno Virtual frente a la modalidad presencial. Se puede concluir que la implementación de b-learning en el ámbito de la enseñanza universitaria representó un gran desafío al tener que afrontar cambios metodológicos al incorporar a las prácticas tradicionales nuevas prácticas educativas. Así, el impacto de la utilización del recurso virtual como complemento a la enseñanza presencial ha sido positivo en la formación de alumnos que cursan la Sección, contribuyendo al mejoramiento de los procesos de enseñanza y aprendizaje.
Strategies in Managing Rapport in Classroom Discussion
Authors: Reski Reski 
Published: June 2018

ABSTRACT
This paper aims to find out the strategies, applied by students in classroom interaction particularly in discussion, to maintain their interpersonal rapport as well as to enhance their rapport management with their fellow students. There are five strategies based on Spencer-Oatey (2008) that the interactants apply in social interactions. The strategies are request, compliments, apologies, gratitude and disagreement. The research is done to see whether the students realize the management of rapport in social interaction and their strategies that they would apply in classroom discussion. The research is done by using descriptive qualitative method to identify the students’ strategies in maintaining their interpersonal rapport and enhancing the rapport management with their fellow students. The data was obtained by video-recording the interactions of the students during the classroom discussions and by giving the students some questionnaires. The researcher also applied the participant observation to see the students reactions during the discussion considering that the strategies that the students apply may bring about the rapport threat and enhancement which are subjective evaluations, which depend not simply on the content of the message, but on people’s interpretations and reactions to who says what under what circumstances. The research indicates that the students’ mostly applied strategy is disagremeent and the type of the disagreement is token agreement. In other words, the students tend to hold the rapport enhancement behavior since in expressing their disagreement, they initially expressed their agreement as a token of appreciation.
Keywords:classroom discussion, interpersonal rapport, rapport management, rapport orientation
In the service of artists – symbiosis and creative engagement in collection development strategy at NIVAL: National Irish Visual Arts Library
Authors: Romano Donna 
Published: June 2018

This paper explores the essential and dynamic relationship between the artist and the institution in building the public record of arts activity. It examines the lifecycle of artist-generated documentation and the various methods of engagement with the library that result in material contributions to the collection.Taking the view that NIVAL is an essentially democratic project in both collection development and access strategies, the paper presents an introduction to the genesis of the library, and outlines some of the ways in which contemporary artists are supporting the role of NIVAL as ‘living archive’. The paper examines a number of recent collaborative projects with practising artists including Jennie Guy, artists’ collaborative Floating World and National College of Art & Design Communication Design students that attest to the regenerative effect of direct engagement by artists in the process of legacy building.
Monumental Latin Inscriptions from Roman Britain in the Ashmolean Museum Collection
Authors: Cooley Alison E. 
Published: June 2018

AbstractThis article presents some of the results of the Ashmolean Latin Inscriptions Project (funded by the AHRC 2013–2017), with new editions and commentaries on inscriptions from Roman Britain in the Ashmolean Museum. It offers an evaluation of these inscriptions based upon autopsy and digital imaging (Reflectance Transformation Imaging), and includes new photographs of them. It offers insights into the culture and society of Roman Britain as well as into the changing attitudes towards Romano-British antiquities in modern Britain from the 1600s onwards.
Comparison of Efficacy, Embolism Rate and Safety of Thrombectomy with Stent Retrievers in an Anterior Circulation Stroke Model
Authors: Larsen Naomi , Oberbeck Katharina , Lima de Miranda Rodrigo , Trentmann Jens , Madjidyar Jawid , Quandt Eckhard , Jansen Olav 
Published: June 2018

Purpose Various stent retrievers differing in stent design and mechanical properties are currently available for the treatment of ischemic stroke. We conducted this in vitro study to compare the efficacy, embolism rate, and safety of commercially available stent retrievers and prototypes.
Materials and Methods Whole blood thrombi were produced in a Chandler loop. The thrombi were inserted into the curved M1 segment of a silicone model of the anterior cerebral circulation. Thrombectomy maneuvers were performed with six commercially available stent retrievers and 2 prototypes with different strut thickness. Wall-stent apposition, first pass recanalization rate, retraction force, and embolism rate were compared.
Results Devices with complete wall-stent apposition had the highest first pass recanalization rate and lowest embolism rate, but showed the highest retraction force. The prototype with thinner struts had a comparable recanalization and embolism rate, while a lower retraction force had to be applied compared to the prototype with thicker struts.
Conclusion Complete wall-stent apposition facilitates a higher recanalization rate and lower embolism rate but also correlates to a higher necessary retraction force and thus possibly higher risk of endothelium damage. Stent modifications leading to a reduced retraction force do not compromise efficacy and embolism rate.
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