bluuebunny/crossref_metadata_2025_split huggingface dataset:
The role of environmental CSR practices on the formation of behavioral intentions in a certified hotel context
Authors: Martínez García de Leaniz Patricia , Herrero Crespo Ángel , Gómez-López Raquél 
Published: April 2019

PurposeThis study aims to explore the relationships among green practices, environmental corporate social responsibility (CSR) image, customers’ trust and their behavioral intentions in a certified hotel context and examine the moderating effect of customers’ involvement in the buying process.Design/methodology/approachA survey was used to collect data from Spanish hotel customers. A structural equation model was developed to assess the research hypotheses.FindingsConsumers’ trust on environmentally certified hotels has a direct effect on their behavioral intentions. Environmental CSR image has a direct effect on consumers’ trust on environmentally certified hotels, but it does not exert significant influence on consumers’ behavioral intentions. Additionally, the results support a positive and significant influence of consumers’ perceptions of green practices on the environmental CSR image of hotels. Finally, there is not a moderating effect of consumers’ involvement on the effects of green practices on CSR environmental image and of this variable on behavioral intentions.Research limitations/implicationsTo cross validate the results of this study, it is recommended that the formation of behavioral intentions in various types of environmentally certified hotel settings be investigated in future research.Practical implicationsHospitality managers should design strategies to raise the perception of the green-related features of environmentally certified companies.Originality/valueNo prior study investigates the relationship between green practices, customers’ trust, their degree of involvement in the buying process and their behavioral intentions in relation to companies’ environmental CSR image in the hotel sector.
Moving between wage work and retirement – the commitment to wage work in later life in Hong Kong
Authors: Tam Yeuk Mui May , Chan Kam Wah , Lo Ka Man 
Published: April 2019

Purpose
Relatively few studies about retirement transition examine economies, where a public pension system is absent. This paper aims to fill this gap in the literature.

Design/methodology/approach
The present study draws on the stratification and risk society approach, as well as results from unstructured interviews with 12 Chinese in Hong Kong.

Findings
The analyses show that the retirement transition involves moving between different forms of wage work and non-work status. These moves were undertaken because of not only financial needs but also a strong desire to be a financially self-reliant and intrinsic commitment to employment. The authors argue that the desire and commitment to employment are shaped by the underdeveloped pension system, practical orientation towards traditional Chinese filial piety norms and personal work history.

Research limitations/implications
The current research covers only a very small sample and uses retrospective interviewing instead of a larger and/or representative sample using prospective panel interview. Nevertheless, the research carries theoretical and policy implications of the study on retirement transition and protection.

Originality/value
Few local studies track retirement transitions in the way similar to the current studies. Existing studies are mostly about advanced Anglo-Saxon economies with a long history of public pension, albeit reformed in recent year, in place. The current study adds to the general literature on retirement studies.
Exposure to males, but not receipt of sex peptide, accelerates functional ageing in female fruit flies
Authors: Bretman Amanda , Fricke Claudia 
Published: April 2019

Abstract

Increased exposure to males can affect females negatively, reducing female life span and fitness. These costs could derive from increased mating rate and also harassment by males. Additionally, early investment in reproduction can increase the onset or rate of senescence in reproductive traits. Hence, there is a tight link between reproduction and ageing.

Here, we assess how mating and encounter rate with males impacts declines in female functional traits that are not directly involved in reproduction. In Drosophila melanogaster fruit flies, exposure to males and mating reduces female life span through harassment and receipt of seminal proteins, including sex peptide (SP). We manipulated the intensity of female exposure to males and regularly assessed female stress responses and recorded physiological traits over her lifetime.

Both mating itself and increased exposure to males accelerate declines in female climbing ability and starvation resistance. However, this is not related to changes in female body mass or fat storage. Moreover, these declines are not driven by the receipt of SP.

Our results suggest some synchrony in senescence across traits in response to female exposure to males; however, this is not universal, as we did not find this for physiological traits. Synchrony in senescence has been theorized but little supported in the literature. It is clear that ageing is a multifaceted trait; to understand environmental impacts on ageing rates, we must measure more than life span and indeed measure senescence in multiple traits. Specifically, our work shows that we must identify which female traits are sensitive to elevated mating activity to understand the impact of antagonistic interactions between the sexes on female ageing patterns.

A plain language summary is available for this article.
Deficits of visual search in Chinese children with dyslexia
Authors: Liu Sisi , Wang Li‐Chih , Liu Duo 
Published: April 2019

BackgroundThere is emerging evidence that individuals with developmental dyslexia show deficits in visual–spatial attention. This study focused on visual searches and examined whether visual search deficits would be found in Chinese children with dyslexia. More importantly, we examined the associations between dyslexia and distinct types of visual searches, to determine whether deficits are specific to some visual searches but not others.MethodsThe dyslexic children and their age‐matched typical peers completed both the inefficient and relatively efficient search tasks.ResultsThe dyslexic children were generally impaired in visual searches, although the deficit in inefficient searches was more severe than in efficient searches. After phonological awareness, working memory and nonverbal IQ were considered; inefficient searches were found to be selectively impaired.ConclusionsThese findings suggest that visual search deficits in dyslexia are universal across alphabetic and logographic writing systems. They highlight the importance of further study on the role of top‐down attention on reading.
A novel biomechanical approach for animal behaviour recognition using accelerometers
Authors: Chakravarty Pritish , Cozzi Gabriele , Ozgul Arpat , Aminian Kamiar 
Published: April 2019

Abstract

Data from animal‐borne inertial sensors are widely used to investigate several aspects of an animal's life, such as energy expenditure, daily activity patterns and behaviour. Accelerometer data used in conjunction with machine learning algorithms have been the tool of choice for characterising animal behaviour. Although machine learning models perform reasonably well, they may not rely on meaningful features, nor lend themselves to physical interpretation of the classification rules. This lack of interpretability and control over classification outcomes is of particular concern where different behaviours have different frequency of occurrence and duration, as in most natural systems, and calls for the development of alternative methods. Biomechanical approaches to human activity classification could overcome these shortcomings, yet their full potential remains untapped for animal studies.

We propose a general framework for behaviour recognition using accelerometers, and develop a hybrid model where (a) biomechanical features characterise movement dynamics, and (b) a node‐based hierarchical classification scheme employs simple machine learning algorithms at each node to find feature‐value thresholds separating different behaviours. Using triaxial accelerometer data collected on 10 wild Kalahari meerkats, and annotated video recordings of each individual as groundtruth, this hybrid model was validated in three scenarios: (a) when each behaviour was equally represented (EQDIST), (b) when naturally imbalanced datasets were considered (STRAT) and (c) when data from new individuals were considered (LOIO).

A linear‐kernel Support Vector Machine at each node of our classification scheme yielded an overall accuracy of >95% for each scenario. Our hybrid approach had a 2.7% better average overall accuracy than top‐performing classical machine learning approaches. Further, we showed that not all models with high overall accuracy returned accurate behaviour‐specific performance, and good performance during EQDIST did not always generalise to STRAT and LOIO.

Our hybrid model took advantage of robust machine learning algorithms for automatically estimating decision boundaries between behavioural classes. This not only achieved high classification performance but also permitted biomechanical interpretation of classification outcomes. The framework presented here provides the flexibility to adapt models to required levels of behavioural resolution, and has the potential to facilitate meaningful model sharing between studies.
Erosive pustular dermatosis of the scalp – an Australian perspective: Insights to aid clinical practice
Authors: Yeh Rudy , Polcz Margit , Wong David 
Published: April 2019

AbstractErosive pustular dermatosis of the scalp has particular relevance in Australia, due to its association with actinic damage. Despite its rarity, the recalcitrant nature of erosive pustular dermatosis of the scalp dictates a protracted recovery fraught with relapse and recurrence, posing inherent challenges to successful treatment and complete recovery. In Australia, erosive pustular dermatosis of the scalp is prevalent in the elderly, who are negatively affected due to the condition. We propose a management outline to aid clinical practice, to improve the quality of life in the elderly, whilst providing insight into the current understanding and treatment of erosive pustular dermatosis of the scalp.
Efficacy of a remote screening model for oral potentially malignant disorders using a free messaging application: A diagnostic test for accuracy study
Authors: Vinayagamoorthy Kalaiselvi , Acharya Shruthi , Kumar Mathangi , Pentapati Kalyana Chakravarthy , Acharya Shashidhar 
Published: April 2019

AbstractObjectiveTo assess the feasibility of using a remote sensing model as a free messaging application tool in the preventive screening of oral potentially malignant disorders in a rural area of India.DesignAn observational cross‐sectional study.SettingPrimary care setting in Udupi District, Karnataka, South India.ParticipantsOne‐hundred and thirty‐one individuals with a mean (SD) age of 37.34 (11.31) years, of whom 64.1% and 35.9% were men and women, respectively.InterventionsClinical oral examination followed by photo capture of five areas of the patients' mouth.Main outcome measuresReliability measures for the use of a photo messaging service in diagnosing oral potentially malignant disorders, as compared to the clinical examination.ResultsWhen lesions were categorised as normal and abnormal, the reliability (kappa) between the diagnoses, based on photo messaging and clinical oral examination, was 0.68 and 0.67 for Examiners 1 and 2, respectively. The sensitivity values for Examiners 1 and 2 were 98.5% and 99.04%, respectively, whereas the specificity was 72% and 64%, respectively. When the agreement between photo messaging and clinical oral examination for an exact diagnostic match was assessed, the reliability (kappa) was 0.59 and 0.55 for Examiners 1 and 2, respectively. The sensitivity values for Examiners 1 and 2 were 98.1% and 98.7%, respectively, whereas the specificity was 64% and 52% respectively.ConclusionThere was a substantial agreement between the diagnosis based on clinical examination and WhatsApp image for both the examiners, when the lesions were dichotomised as normal and abnormal, but slightly reduced when assessed for the exact diagnostic match. Screening for oral potentially malignant disorders using photo messaging can serve as an effective adjunct and a potential cost‐effective tool in a low‐resource setting.
Young bisexual women's sexual health care experiences in Australian rural general practice
Authors: Grant Ruby , Nash Meredith 
Published: April 2019

AbstractObjectiveTo examine how young bisexual women in rural Tasmania experience routine sexual health care in general practice settings.DesignSemi‐structured interviews with bisexual women were used for this study. Self‐selected and purposive sampling were used to recruit women in 2015. Participants were recruited via community social media pages and a not‐for‐profit organisation supporting same‐sex attracted rural youth. Data were analysed thematically.SettingRegional and rural areas in the north and south of Tasmania, Australia.ParticipantsFifteen bisexual women, 18‐26 years of age, with experience seeking sexual health care in Tasmania.Main outcome measure(s)Semi‐structured interviews explored women's experiences of inclusive sexual health care.ResultsFour key themes emerged from the thematic analysis: (a) issues of health care accessibility in rural Tasmania; (b) the importance of visual signs of inclusivity in rural clinics; (c) practitioner attitudes; and (d) use of inclusive, gender‐neutral language.ConclusionsRural bisexual women prefer practitioners who make meaningful efforts to be inclusive and take a non‐judgmental approach to sexual health care. Additional resources are needed to support rural communities and their health care providers to prioritise inclusive health practices.
Sex differences in adverse drug reactions reported to the National Pharmacovigilance Centre in the Netherlands: An explorative observational study
Authors: de Vries Sieta T. , Denig Petra , Ekhart Corine , Burgers Jako S. , Kleefstra Nanno , Mol Peter G.M. , van Puijenbroek Eugène P. 
Published: April 2019

AimsWe aimed to assess and characterize sex differences in adverse drug reactions (ADRs) reported to the national pharmacovigilance centre in the Netherlands while considering differences in drug use.MethodsADRs spontaneously reported by healthcare professionals and patients to the Netherlands pharmacovigilance centre Lareb were used. Drug–ADR combinations reported at least 10 times between 2003–2016 for drugs used by ≥10,000 persons in that period were included. Data about the number of drug users was obtained from the National Health Care Institute. Sex‐specific ADRs, like gynaecological problems, were excluded. Sex differences in specific drug–ADR combinations were tested using bivariate logistic regression analyses in which the number of drug users per sex was taken into account.ResultsIn total, 2483 drug–ADR combinations were analysed. Possibly relevant sex differences were shown in 363 combinations (15%). Most of these drug–ADR combinations were reported more often for women (322 combinations). Drugs with the highest number of ADRs that were more often reported for women included thyroid hormones (32 combinations) and antidepressants (16 combinations for the centrally acting sympathomimetics; 14 combinations for other antidepressants). Some ADRs were predominantly reported for women across a range of drugs such as headache and dizziness whereas other ADRs such as tendon ruptures and aggression were reported more often for men.ConclusionsIdentified sex differences in reported ADRs often referred to women. These differences may have various causes, including pharmacological and behavioural causes, which need to be further assessed. The results may ultimately lead to sex‐specific prescribing or monitoring recommendations.
External cephalic version at term: A 6‐year single‐operator experience
Authors: Levin Gabriel , Rottenstreich Amihai , Weill Yishay , Pollack Raphael N. 
Published: April 2019

AbstractBackgroundExternal cephalic version (ECV) should be offered for patients presenting with a noncephalic pregnancy that are willing to deliver vaginally. Various reports have evaluated predictors for successful ECV. Yet, none have reported a single‐operator large cohort experience. We aim to analyze the outcome of referrals for ECV.MethodsWe conducted a retrospective cohort study of prospectively collected data. We performed a multivariate analysis of data with respect to ECV procedures performed by a single operator in a 6‐year period. Maternal and fetal characteristics were compared between ECV success and failure groups.ResultsSix hundred and two women underwent ECV. Of them, ECV was successful in 432 (71.7%). A multivariate binary logistic regression model demonstrated that high liquor volume was a predictor of ECV success (Adj OR 1.17 [95% CI 1.09‐1.26]). Failure of ECV was correlated with anterior placenta (0.44 [0.56‐0.76]) and nulliparity (0.21 [0.11‐0.36]). Adverse events were rare and mostly minor, occurring in 1% of procedures.ConclusionsECV has a high success rate and a low complication rate, enabling vaginal birth and avoiding cesarean. The role of manipulation of modifiable determinants such as liquor volume should be further assessed in future studies.
Outcomes of second allogeneic haematopoietic stem cell transplantation in patients with relapse of myelodysplastic syndrome
Authors: Shimomura Yoshimitsu , Hara Masahiko , Tachibana Takayoshi , Ohashi Kazuteru , Sakura Toru , Fukuda Takahiro , Nakazawa Hideyuki , Iwato Koji , Kanda Yoshinobu , Ikeda Takashi , Eto Tetsuya , Kanda Junya , Ichinohe Tatsuo , Atsuta Yoshiko , Ishikawa Takayuki , Ishiyama Ken 
Published: April 2019

SummaryThough second allogenic haematopoietic stem cell transplantation (HSCT) is considered a curative treatment option after myelodysplastic syndrome (MDS) relapse, scant epidemiological data are available. We investigated the outcomes and prognostic factors of second allogenic HSCT in 99 patients with MDS who relapsed after the first HSCT. The median age was 53 years (interquartile; 45–59) and 57 patients (57·6%) were male. Five‐year overall survival was 25·3%. Early relapse (adjusted hazard ratio: 2·78, 95% confidence interval: 1·08–7·21, P = 0·035) and poor performance (3·03, 1·71–5·37, P < 0·001) were associated with a significantly poor 5‐year overall survival compared to the other groups (P < 0·001).
Consensus recommendations for diagnosis, management and treatment of Fabry disease in paediatric patients
Authors: Germain Dominique P. , Fouilhoux Alain , Decramer Stéphane , Tardieu Marine , Pillet Pascal , Fila Marc , Rivera Serge , Deschênes Georges , Lacombe Didier 
Published: April 2019

AbstractFabry disease (FD), a rare X‐linked disease, can be treated with bi‐monthly infusion of enzyme replacement therapy (ERT) to replace deficient α‐galactosidase A (AGAL‐A). ERT reduces symptoms, improves quality of life (QoL), and improves clinical signs and biochemical markers. ERT initiation in childhood could slow or stop progressive organ damage. Preventative treatment of FD from childhood is thought to avoid organ damage in later life, prompting a French expert working group to collaborate and produce recommendations for treating and monitoring children with FD. Organ involvement should be assessed by age 5 for asymptomatic boys (age 12‐15 for asymptomatic girls), and immediately for children diagnosed via symptoms. The renal, cardiac, nervous and gastrointestinal systems should be assessed, as well as bone, skin, eyes, hearing, and QoL. The plasma biomarker globotriaosylsphingosine is also useful. ERT should be considered for symptomatic boys and girls with neuropathic pain, pathological albuminuria (≥3 mg/mmol creatinine), severe GI involvement and abdominal pain or cardiac involvement. ERT should be considered for asymptomatic boys from the age of 7. Organ involvement should be treated as needed. Early diagnosis and management of FD represents a promising strategy to reduce organ damage, morbidity and premature mortality in adulthood.
Integration of transanal techniques for precise rectal transection and single‐stapled anastomosis: a proof of concept study
Authors: Spinelli A. , Carvello M. , D'Hoore A. , Foppa C. 
Published: April 2019

AbstractAimTransection of the distal rectum and subsequent anastomosis differ between the open, minimally invasive and transanal approaches. With the transanal technique, there is direct control of the transection level and the single‐stapled anastomosis, thus overcoming two crucial limitations of rectal surgery. This study describes a technique for precise a transanal rectal transection with a single‐stapled (TTSS) colorectal, coloanal or ileoanal anastomosis in 20 consecutive patients undergoing low rectal surgery.MethodsAfter completing rectal dissection by the preferred technique (open or minimally invasive), TTSS was created. The detailed video describes this technique.ResultsTTSS was feasible in all patients: 13 underwent total mesorectal excision + TTSS for low rectal cancer and seven underwent ileoanal pouch + TTSS for benign disease. Complications included one Grade IIIa and three Grade I, according to the Clavien–Dindo classification (median follow‐up 6 months).ConclusionTTSS represents a technique which can be applied regardless of the preferred approach (open, minimally invasive or transanal) for low rectal dissection. The adoption of TTSS could well allow for a more consistent comparison of the outcomes following the differing approaches to rectal surgery.
Studies on differentiation‐dependent expression and activity of distinct transglutaminases by specific substrate peptides using three‐dimensional reconstituted epidermis
Authors: Tanabe Yuki , Yamane Miki , Kato Manami , Teshima Hirofumi , Kuribayashi Miki , Tatsukawa Hideki , Takama Hiroyuki , Akiyama Masashi , Hitomi Kiyotaka 
Published: April 2019

During skin formation, particularly during differentiation of keratinocytes, unique post‐translational modifications play a role in forming a proteinaceous supermolecule called the cornified envelope (CE), which is necessary for barrier function. Transglutaminases (TGs) are essential enzymes involved in the cross‐linking of various keratinocyte structural proteins to complete CE formation. The TG family consists of eight isozymes, with two members, TG1 and TG3, located mainly in the epidermis. In an in vitro three‐dimensional (3D) culture system, reconstruction of the epidermis allows cornification of the terminally differentiated keratinocytes. In this study, using isozyme‐specific substrate peptides that enable detection of TG activity, we investigated the expression and the activation pattern of each isozyme during differentiation in this culture system. In the differentiating cells, the protein levels, enzymatic activities, as well as localization of TG1 and TG3 exhibited distinct patterns. Specific knockdown of these enzymes by siRNA revealed less cornification, suggesting that each TG contributes to the epidermal formation. In conclusion, we demonstrate the efficiency of the 3D system for studying differentiation‐dependent expression and activity of distinct TGs by specific substrate peptides.EnzymeTransglutaminase, EC2.3.2.13.