bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pragmatic implementation of low-intensity psychological treatment for children and young people: the reality
Authors: Roach Anna , Stokes Isabella , McDonnell Katie , Griffiths Helen , Curry Vicki , Heyman Isobel , Balakrishnan Sonia , Ndoci Xhorxhina , Bennett Sophie D. , Shafran Roz 
Published: November 2024

Abstract

Background and aims:
Low-intensity psychological interventions are effective for children and young people (CYP) with mental health difficulties and can help bridge the demand–capacity gap. Despite increasing awareness, training and use of low-intensity psychological interventions, it is not yet understood what is being implemented in clinical practice in the UK and the associated evidence base.

Method:
This paper presents two studies; first, a national survey (n=102) of practitioners to identify low-intensity psychological interventions currently delivered in practice and second, an exploration of the availability and the strength of empirical support (characterised as ‘gold’, ‘silver’ and ‘bronze’) of low-intensity CBT interventions for CYP.

Results:
The first study found a wide variety of interventions being used across different services; 101/102 respondents reported using routine outcome measures. The second study identified 44 different low-intensity interventions, 28 of which were rated as having gold empirical support. However, only 13 of the gold interventions were considered accessible for practitioners and only two were reported being used in routine practice.

Conclusion:
These findings highlight that these interventions have been developed and empirically tested, but many are not easily accessible, highlighting the ‘research–practice’ gap in the provision of low-intensity interventions. There is a need for an increase in standardisation of care and accessibility of gold interventions. This paper hopes to begin the process of creating a hub of low-intensity interventions that are accessible and empirically supported to improve equity of access and outcomes of low-intensity psychological interventions for CYP.
Prenatal iodine intake and infant temperament in a multiethnic US cohort
Authors: Akinkugbe Aderonke A , Duffy Julia , Kannan Srimathi , Hartman Terryl J , Landero Julio , Bosquet Enlow Michelle , Wright Robert O , Zhang Xueying , Wright Rosalind J 
Published: November 2024

Abstract

Objective:
Maternal iodine plays a central role in fetal neurodevelopment. It is recommended that pregnant women consume sufficient levels of iodine to accommodate increased need for mother and fetus. We examined associations among prenatal dietary and supplemental iodine intake and infant temperament.

Design:
The PRogramming of Intergenerational Stress Mechanisms (PRISM) study is an ongoing longitudinal pregnancy cohort. Data from 2011 to 2020 were used for this study. Women completed the Block98 FFQ ascertaining prenatal dietary and supplemental iodine intake and the Infant Behavior Questionnaire-Revised at infant age 6 months to ascertain infant temperament (Surgency/Extraversion, Negative Affectivity and Orienting/Regulation).

Setting:
USA.

Participants:
Mother–child dyads (n 892).

Results:
Women were primarily Black/Hispanic Black (44 %) and non-Black Hispanic (35 %) with 46 % reporting household income < $25 000/year. Nearly half had an estimated average requirement (EAR) < 160 µg/d (49 % based on dietary intake; 43 % based on diet and supplements). Girls born to women with an EAR ≥ 160 µg/d compared to girls born to women below this level had higher unadjusted extraversion scores for dietary plus supplemental intake (β = 0·23 (0·13, 0·33)); decreased to β = 0·05 (–0·08, 0·19) after adjusting for covariates. Boys born to women with an EAR ≥ 160 µg/d (based on diet and supplements) as compared to boys born to women below this level had statistically non-significant higher unadjusted negative affective score (β = 0·06 (–0·08, 0·20)) that became significantly lower upon covariate adjustment (β = –1·66 (–1·97, –1·35)).

Conclusions:
A significant proportion of these women reported suboptimal prenatal iodine intake. Suboptimal prenatal iodine intake may have implications for child neurodevelopment evident as early as infancy.
Effects of probiotics on selected anthropometrics and biochemical measures in overweight or obese Saudi subjects: a double-blind, placebo-controlled, randomised clinical trial
Authors: AlMalki Samira M , Alfawaz Hanan A , Binmoammar Turki A , AlBahlei Saleh F , Al Bakr Luluah M , Alzahrani Ahmed M , Alshammari Salem S , Hussain Syed Danish , Sabico Shaun , Al-Daghri Nasser M 
Published: November 2024

Abstract

Objective:
This study aimed to assess the effects of multi-strain probiotics on anthropometric and biochemical measures in Saudi adults with overweight or obesity.

Design:
Single-centre, double-blind, placebo-controlled, randomised clinical trial.

Setting:
Occupational Health Clinics at King Saud University Medical City, Riyadh, Saudi Arabia.

Participants:
Ninety-three Saudi participants with overweight or obesity were randomly assigned to receive twice-daily doses of either placebo (n 49) or 30 × 109 CFU/g of HEXBIO® containing three Lactobacillus and three Bifidobacterium species (n 44) in a double-blind manner over a 12-week period, respectively. Both groups adhered to a hypoenergetic diet. Anthropometric measurements, glycaemic indices and lipid profiles were evaluated at baseline and post-intervention.

Results:
Following the 12-week intervention, no statistically significant differences were found in all between the probiotic group and placebo group comparisons, except for fat intake, where the group*time interaction showed a significant decrease in favour of the probiotic group (P = 0·02). However, significant within-group reductions were observed in the probiotic group: body weight (–0·9 kg, P = 0·02), HC (–1·5 cm, P = 0·002), energy intake (–387·3 kcal/d, P = 0·002), fasting glucose (–0·7, P = 0·002) and LDL-cholesterol (–0·7, P = 0·02).

Conclusion:
Consumption of multi-strain probiotic supplementation over 12 weeks significantly decreased fat intake in Saudi adults with overweight or obesity, with the probiotic group highlighting improved anthropometric and biochemical parameters. Further research is needed to evaluate the long-term clinical significance of this dietary practice and whether it has a meaningful impact on overall health beyond the placebo effect.
Religious pluralism of Muslim practices in China: the cases of ritual participation from Hui and Uyghur societies
Authors: Wang Jianxin , Zhang Chenxi 
Published: November 2024

Abstract
In this article we explore the practical conditions of ritual practices of Hui and Uyghur Muslims in China. Ceaseless conflicts among different religious ideas and elements exist, but they are integrated into religious pluralism, which meets the needs of Muslims' daily practices. Furthermore, we probe the reasons for the resulting religious harmony through investigating the historical process of the formation of religious pluralism, and showing present ritual performances in which there is a hierarchically built ritual structure functioning to make religious integration possible, though different opinions regarding diverse religious elements occur elsewhere among Hui and Uyghur Muslims. Finally, the discussion supports the related assertion that rituals can be reliable and effective ways of understanding the sociological and psychological functions of religions, or religious beliefs, and other related socio-cultural realities.
Ways of reading: evaluating different approaches to reading Latin stories with a Year 9 class in a selective boys' school
Authors: Philp Polly 
Published: November 2024

Abstract
Before I started teacher training, my default approach to a story in a Latin textbook was to translate it into English. I assumed that this was how you best understood what was happening in the story, and how you showed that you understood. Although I had done other things as a learner myself, including comprehension exercises, my prevailing memory was of translation. Translation is a highly valued and prioritised skill, as seen in the weight given to it in examinations and assessments – though in my school placements I regularly see ‘translations’ that are near-incomprehensible ‘translationese’ rather than fluent English. This means that often after translating a sentence or passage – a very time-consuming activity – you can ask a student, ‘So, what does that mean? What's going on here?’ and that student will struggle to explain. I therefore wanted to investigate other ways to approach Latin stories. I will not claim that we were reading Latin in the truest sense of reading (left to right, at normal speed, comprehending the Latin in Latin and not needing recourse to English), but the three approaches we explored did engage with the texts without requiring literal English translation.
Evidence for Magnetically‐Driven Accretion in the Distal Solar System
Authors: Mansbach Elias N. , Weiss Benjamin P. , Lima Eduardo A. , Sowell Michael , Kirschvink Joseph L. , Fu Roger R. , Cambioni Saverio , Bai Xue‐Ning , Ream Jodie B. , Anai Chisato , Kobayashi Atsuko , Hidaka Hironori 
Published: November 2024

AbstractPaleomagnetic measurements of meteorites indicate that magnetic fields existed in the inner solar nebula capable of driving accretion at rates similar to those observed for young stellar objects with protoplanetary disks. However, the field strength in the solar system beyond ∼7 astronomical units (AU) and its role in accretion remain poorly constrained. Returned samples from asteroid (162173) Ryugu offer the possibility of determining the nebular field intensity in this distal region. Here, we report paleomagnetic studies of three Ryugu particles which reveal that alteration occurred in the presence of a null or relatively weak (<15.8 μT) field within 3 million years (Ma) after solar system formation. This resolves previously contrasting reports that Ryugu's parent body experienced alteration in the presence of a strong (>80 μT) magnetic field and weak or null field (<3 μT). In addition, we re‐examine previous paleomagnetic and Mn‐Cr chronometry studies of three other distally‐sourced meteorites, Tagish Lake, Tarda, and Wisconsin Range 91600, which measured paleointensities of <0.9, <1.7 and 5.1 ± 4.5 μT respectively. While it was previously unclear whether these records were acquired while the nebula was present, our re‐analysis suggests that their records are sufficiently old (i.e., <3.5 Ma after solar system formation) to be nebular in origin. Collectively, these data demonstrate that the distal solar system nebular field, while faint, was likely still strong enough to drive accretion at rates like those observed in the inner solar system.
Substantial Global Radial Variations of Basalt Content Near the 660‐km Discontinuity
Authors: Hao Shangqin , Wei S. Shawn , Shearer Peter M. 
Published: November 2024

AbstractMid‐ocean ridges generate basalt and harzburgite, which are introduced into the mantle through subduction as a mechanical mixture, contributing to both lateral and radial compositional heterogeneity. The possible accumulation of basalt in the mantle transition zone has been examined, but details of the mantle composition below the 660‐km discontinuity (hereafter d660) remain poorly constrained. In this study, we utilize the subtle waveform details of S660S, the underside shear‐wave reflection off the d660, to interpret the seismic velocity, density, and compositional structure near, and particularly below, the d660. We identify a significant difference in S660S waveform shape in subduction zones compared to other regions. The inversion results reveal globally enriched basalt at the d660, with a notably higher content in subduction zones, consistent with the smaller impedance jump and S660S peak amplitude. The basalt fraction decreases significantly to less than 10% near 800‐km depth, forming a global harzburgite‐enriched layer and resulting in a steep seismic velocity gradient just below the d660, in agreement with 1D global reference models. The striking compositional radial variations near the d660 verify geodynamic predictions and challenge the applicability of homogeneous radial compositional models in the mantle. These variations may also affect the viscosity profile and, consequently, the dynamics at the boundary between the upper and lower mantle.
Quantification of Salt Transports Due To Exchange Flow and Tidal Flow in Estuaries
Authors: Biemond Bouke , de Swart Huib E. , Dijkstra Henk A. 
Published: November 2024

AbstractTo understand mechanisms of salt intrusion in estuaries, we develop a semi‐analytical model, that explicitly accounts for salt transport by both exchange flow and tidal flow. This model, after calibration, successfully hindcasts hydrodynamics and salinity dynamics in three estuaries that have strongly different characteristics. We find, from analyzing the model results for these three estuaries, that salt transport processes by exchange flow and tidal flow interact through the subtidal stratification. Transport by exchange flow creates stratification, thereby generating a phase shift of tidal salinity with respect to the tidal flow, which is important for the magnitude of the tidal salt transport. Conversely, the strength of tidal currents determines the vertical mixing that breaks down stratification. A new analytical formulation is presented for the component of the salt transport driven by the depth‐averaged tidal flow. This salt transport is larger than the component associated with the vertical shear of the tidal current. Finally, a method that yields analytical equations that quantify the importance of different contributions to the salt transport using only primary information is developed using approximate solutions for the subtidal stratification. This method performs well for the estuaries considered.
Impacts of the Arctic Stratospheric Polar Vortex Weakening on Ural Blocking in Boreal Winter
Authors: Qian Cheng , Huang Jinlong , Tian Wenshou , Liu Jinnian , Song Yuanjing , He Li 
Published: November 2024

AbstractUsing the ERA5 reanalysis data, we analyzed the impacts of the Arctic stratospheric polar vortex weakening on Ural Blocking (UB). The results indicate that UB activities are suppressed following the weakening of the polar vortex. Specifically, the probability of UB is significantly reduced, with a maximum decrease of 30% observed around day 24 following the polar vortex weakening. The average life cycle of UB shortens by approximately one day. The amplitude of UB, as measured by the negative potential vorticity (PV) anomalies over the Urals, experiences a significant decrease, particularly with the presence of positive PV anomalies on the western side of Urals. Further analysis indicates that the suppression of UB following the weakened polar vortex is closely linked to both the equatorward horizontal transport of high‐PV air over the Arctic across the dynamic tropopause, and the anomalous increase in static stability over the Urals resulting from a descent of the isentropic surface near the tropopause. Finally, we evaluate the relative roles of the polar vortex weakening and the negative phase of the Arctic Oscillation (AO) in suppressing the development of UB. Our analysis reveals that the impacts of the weak polar vortex on the suppression of UB are stronger and more long‐lasting compared to the negative AO, suggesting that the impacts of the weakened polar vortex on UB cannot be simply explained by the AO response.
Processes Driving the Intermodel Spread of the Southern Hemisphere Hadley Circulation Expansion in CMIP6 Models
Authors: Hur Ije , Yoo Changhyun , Yeh Sang‐Wook , Kim Young‐Ha , Seo Kyong‐Hwan 
Published: November 2024

AbstractThe Hadley circulation (HC) has been expanding poleward in recent decades. The Coupled Model Intercomparison Project Phase 6 (CMIP6) models predict that the expansion will accelerate in the future, more so in the Southern Hemisphere (SH). However, the extent of the expansion varies widely among the models. We investigate the mechanisms driving the intermodel spread in SH HC expansion predictions. The intermodel spread is obtained by an empirical orthogonal function analysis on the SH HC trend patterns of 16 CMIP6 model simulations using the historical and shared socioeconomic pathway 5–8.5 scenarios. The leading mode, showing a mean meridional stream function anomaly at the poleward SH HC extent, explains 49.73% of the variance and significantly correlates (r = 0.94) with the SH HC expansion. By analyzing the extended Kuo‐Eliassen equation, we find that the intermodel difference in the representation of diabatic heating is responsible for about 14% of the intermodel spread. The meridional eddy momentum and heat fluxes contribute to about 21% and 18% of the intermodel spread, respectively. The models simulating a relatively large SH HC expansion tend to show increased precipitation in the Southern Pacific Convergence Zone, reduced baroclinic instability in the subtropics, and an enhanced poleward shift of jet stream in the midlatitudes. This suggests that the uncertainty in the HC projection may be constrained by reducing the bias in the trend of the mean fields.
Dietary intake and sleep in late childhood – do shorter children have distinct patterns?
Authors: Fisch-Shvalb Naama , Zur Maya , Lazar Liora , Shamir Raanan , Phillip Moshe , Yackobovitch-Gavan Michal 
Published: November 2024

Abstract
Background
The exceptional growth rate during adolescence demands increased dietary intake. We aimed to compare diet and lifestyle of pre-adolescents with height and weight below the 10th percentile, with those of pre-adolescents of higher height and weight.

Methods
This case-control study included healthy pre-pubertal girls (≥9 years) and boys (≥10 years). The case groups included 31 girls and 32 boys with height and weight <10th percentile, and weight percentile ≤height percentile. The control groups comprised 24 girls and 24 boys, with height ≥25th percentile, BMI 5th–85th percentiles. Participants completed 3-day food diaries and lifestyle-related questionnaires.

Results
Energy intake/estimated-requirement and protein/body-weight were comparable in the case and control groups, both in boys and girls. In boys, fat (P = 0.050) and carbohydrate (P ≤ 0.001) intakes/body-weight were higher in the case group versus controls; and iron (P < 0.001), zinc (P = 0.005), vitamin A (P < 0.001), calcium (P = 0.005), and vitamin C (P = 0.034) consumption were lower. In girls, carbohydrate/body-weight was higher in the case group compared to controls (P = 0.007); micronutrient intake was comparable, and lower than recommended. Compared to controls, short and thin boys reported less sleep during weekdays (P < 0.001).

Conclusions
Relatively short, thin pre-adolescents may have distinct dietary intake and sleeping patterns compared to taller peers, especially boys.

Impact

Nutrition is a key environmental determinant of childhood growth. Not much is known about late nutritional impact on growth in children whose anthropometric indices are below the 10th percentile.

We compared food diaries and lifestyle questionnaires of pre-pubertal pre-adolescents with height <10th percentiles and weight≤height for age and sex, with those of peers with indices in higher percentiles.

We found distinct differences in micronutrient intakes and sleep duration in the shorter boys, but no energy deficit in either sex.

We suggest that diet and lifestyle parameters should be evaluated in children with relatively low anthropometric indices, to ensure optimal growth.
Metformin improves HPRT1-targeted purine metabolism and repairs NR4A1-mediated autophagic flux by modulating FoxO1 nucleocytoplasmic shuttling to treat postmenopausal osteoporosis
Authors: Yang Keda , Wang Xiaochuan , Zhang Chi , Liu Dian , Tao Lin 
Published: November 2024

AbstractOsteoporosis is a major degenerative metabolic bone disease that threatens the life and health of postmenopausal women. Owing to limitations in detection methods and prevention strategy awareness, the purpose of osteoporosis treatment is more to delay further deterioration rather than to fundamentally correct bone mass. We aimed to clarify the pathogenesis of postmenopausal osteoporosis and optimize treatment plans. Our experiments were based on previous findings that oxidative stress mediates bone metabolism imbalance after oestrogen deficiency. Through energy metabolism-targeted metabolomics, we revealed that purine metabolism disorder is the main mechanism involved in inducing oxidative damage in bone tissue, which was verified via the use of machine-learning data from human databases. Xanthine and xanthine oxidase were used to treat osteoblasts to construct a purine metabolism disorder model. The activity and differentiation ability of osteoblasts decreased after X/XO treatment. Transcriptomic sequencing indicated that autophagic flux damage was involved in purine metabolism-induced oxidative stress in osteoblasts. Additionally, we performed serum metabolomics combined with network pharmacology to determine the pharmacological mechanism of metformin in the treatment of postmenopausal osteoporosis. HPRT1 was the potential target filtered from the hub genes, and FoxO1 signalling was the key pathway mediating the effect of metformin in osteoblasts. We also revealed that SIRT3-mediated deacetylation promoted the nuclear localization of FoxO1 to increase the expression of HPRT1. HPRT1 upregulation promoted purine anabolism and prevented the accumulation of ROS caused by purine catabolism to reverse oxidative damage in osteoblasts. We propose that purine metabolism disorder-induced oxidative stress is important for the pathogenesis of postmenopausal osteoporosis. The therapeutic mechanism of metformin should be confirmed through subsequent drug optimization and development studies to improve bone health in postmenopausal women.
Robustly learning the Hamiltonian dynamics of a superconducting quantum processor
Authors: Hangleiter Dominik , Roth Ingo , Fuksa Jonáš , Eisert Jens , Roushan Pedram 
Published: November 2024

AbstractPrecise means of characterizing analog quantum simulators are key to developing quantum simulators capable of beyond-classical computations. Here, we precisely estimate the free Hamiltonian parameters of a superconducting-qubit analog quantum simulator from measured time-series data on up to 14 qubits. To achieve this, we develop a scalable Hamiltonian learning algorithm that is robust against state-preparation and measurement (SPAM) errors and yields tomographic information about those SPAM errors. The key subroutines are a novel super-resolution technique for frequency extraction from matrix time-series, tensorESPRIT, and constrained manifold optimization. Our learning results verify the Hamiltonian dynamics on a Sycamore processor up to sub-MHz accuracy, and allow us to construct a spatial implementation error map for a grid of 27 qubits. Our results constitute an accurate implementation of a dynamical quantum simulation that is precisely characterized using a new diagnostic toolkit for understanding, calibrating, and improving analog quantum processors.