bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of novel functions of three genes in oriental river prawn,Macrobrachium nipponense: Molecular Cloning, Expression, andIn situHybridization Analysis
Authors: Jin Shubo , Fu Hongtuo , Hu Yuning , Sun Shengming , Jiang Sufei , Xiong Yiwei , Qiao Hui , Zhang Wenyi , Gong Yongsheng , Wu Yan 
Published: October 2018

AbstractThree genes were predicted to be potentially involved in the male sexual development inM.nipponense, including the Gem-associated protein 2-like isoform X1 (GEM), Ferritin peptide, and DNA polymerase zeta catalytic subunit (Rev3). In this study, we aimed to investigate their novel functions in depth. The full-length cDNA sequence of Mn-GEM was 1,018 bp, encoding 258 amino acids. The partial Mn-Rev3 cDNA sequence was 6,832 bp, encoding 1,203 amino acids. Tissue distribution indicated that all of these three genes have higher expression level in testis and androgenic gland, implying their novel functions in male sexual development. In situ hybridization analysis further confirmed the novel roles of these three genes. Rev3 promote the testis development during the whole reproductive cycle, while GEM and ferritin only promote the activation of testis development. Besides, these three genes play essential roles in funicular structure development surrounding the androgenic gland cells, which promote and support the formation of androgenic gland cells. The expression in hepatopancreas cells also suggested their role in immune system inM. nipponense.This study advances our understanding of male sexual development inM. nipponense, as well as providing the basis for further studies of male sexual differentiation and development in crustaceans.
Prevalence and correlates of anemia among children aged 6-23 months in Wolaita Zone, Southern Ethiopia
Authors: Alemayehu Mihiretu , Meskele Mengistu , Alemayehu Bereket , Yakob Bereket 
Published: October 2018

AbstractBackgroundAnemia, the world’s most common micro-nutrient deficiency disorder, can affect a person at any time and at all stages of life, although children aged 6 -23 months are particularly at higher risk. If left untreated, it adversely affects the health, cognitive development, school achievement, and work performance. However, littlewas investigated among young children in Sub-Saharan countries including Ethiopia. This research aimed to investigate its magnitude and correlates to address the gap and guide design of evidence based intervention.MethodsA community-based cross-sectional study was conducted from May -June 2016 in rural districts of Wolaita Zone. Multi-stage sampling technique was applied to select 990 mother-child pairs. Socio-demography, health and nutritional characteristics were collected by administering interview type questionnaire to mothers/care-givers. Blood samples were taken to diagnose anemia by using HemoCue device, and status was determined using cut-offs used for children aged 6-59 months. Hemoglobin concentration below 11.0 g/dl was considered anemic. Data were analyzed with Statav 14. Bivariate and multivariable logistic regressions were applied to identify candidate and predictor variables respectively. Statistical significance was determined at p-value < 0.05 at 95% confidence interval.ResultsThe mean hemoglobin level of children was 10.44±1.3g/dl, and 65.7% of them were anemic. Among anemic children, 0.4% were severely anemic (<7.0g/dl), while 28.1% and 37.2% were mildly (10.0-10.9g/dl) and moderately (7.0-9.9g/dl) anemic, respectively. In the multivariable analysis, having maternal age of 35 years and above (AOR=1.96), being government employee (AOR=0.29),being merchant (AOR= 0.43) and ‘other’ occupation (AOR=3.17) were correlated with anemia in children in rural Wolaita. Similarly, receiving antihelminthic drugs (AOR= 0.39), being female child (AOR= 1.76), consuming poor dietary diversity (AOR=1.40), and having moderate household food insecurity (AOR=1.72) were associated with anemia in rural Wolaita.ConclusionA large majority of children in the rural Wolaita were anemic and the need for proven public health interventions such as food diversification, provision of anti-helminthic drugs and ensuring household food security is crucial. In addition, educating women on nutrition and diet diversification, as well as helping them with alternative sources of income might be interventions in the study area.
Deficient skeletal muscle regeneration after injury induced by a Clostridium perfringens strain associated with gas gangrene
Authors: Zúñiga-Pereira Ana Mariel , Carlos Santamaría Carlos , Gutiérrez José María , Alape-Girón Alberto , Flores-Díaz Marietta 
Published: October 2018

AbstractVery little is known about the muscle regeneration process that follows myonecrosis induced by C. perfringens, the main agent of gas gangrene. This study revealed that, in a murine model of the infection with a sublethal inoculum of C. perfringens, muscle necrosis occurs concomitantly with significant vascular damage, which limits the migration of inflammatory cells. A significant increase in cytokines that promote inflammation explains the presence of inflammatory infiltrate; however, an impaired IFNγ expression, a reduced number of Ml macrophages, a deficient phagocytic activity, and the prolongation of the permanence of inflammatory cells, lead to deficient muscle regeneration. The expression of TGFβ1 and the consequent accumulation of collagen in the muscle, likely contribute to the fibrosis observed 30 days after infection. These results provide new information on the pathogenesis of gas gangrene caused by C. perfringens, shed light on the basis of the poor muscle regenerative activity, and may open new perspectives for the development of novel therapies for patients suffering this disease.
Corrosion of steel due to iron oxidizing bacteria
Authors: Sachan Reena , Singh Ajay Kumar 
Published: October 2018

PurposeThe purpose of this study is to investigate microbial influenced corrosion of steel because of iron oxidizing bacteria (IOB).Design/methodology/approachCarbon steel was selected for this study. Winogradsky media was used for isolation of IOB and as test solution for corrosion measurements. Electrochemical tests and immersion test were conducted to estimate the corrosion rate and extent of pitting. The corroded surface was analysed by SEM and corrosion products formed over the metal surface were identified by XRD and Fourier transformed infrared. Biofilm formed over the corroded metal was analysed by UV-visible spectroscopy for its extracellular polymeric substances (EPS) constituents.FindingsPresence of IOB in Winogradsky medium enhances corrosion. Uniform and localized corrosion increases with increased bacterial concentration and EPS constituents of the biofilm. Iron sulphite formation as one of the corrosion products has been suggested to be responsible for increased corrosion attack in the inoculated media in comparison to control media where corrosion product observed is iron hydrogen phosphate which is protective in nature.Originality/valueThis work correlates increased corrosion of steel in the presence of bacteria with the nature of corrosion products formed over it in case of IOB. Formation of corrosion products is governed by various electrochemical reactions; hence, inhibition of such reactions may lead to reduce or stop the formation of such products which enhances corrosion and thereby may reduce the extent of microbial induced corrosion.
Effects of second phases on the formation mechanism and corrosion resistance of phosphate conversion film on AZ80 Mg alloy
Authors: Xu Zubin , Song Yingwei , Dong Kaihui , Shan Dayong , Han En-Hou 
Published: October 2018

Purpose
The formation and corrosion processes of a conversion film on the AZ80 Mg alloy with different second phases were compared to clarify the effect of microstructure on the quality of protective coatings.

Design/methodology/approach
The size and distribution of second phases in the edge and central regions of the AZ80 cast ingot exhibit a great difference. The film growth processes and their corrosion resistance on the edge and central regions of the AZ80 cast ingot were investigated by scanning electron microscope observations, immersion tests and electrochemical measurements.

Findings
The results indicate that second phases act as micro-cathodes and hydrogen evolution reaction occurs on their surface, which is not beneficial for the deposition of the conversion film.

Originality/value
The conversion film formed on the central regions of AZ80 cast ingot with a low volume fraction of second phases exhibits a more uniform surface and higher corrosion resistance than that formed on the edge regions of the sample with a higher volume fraction of second phases.
Partially feasible solution space for integrated SATS operations
Authors: Miksa Wojciech Jerzy , Goetzendorf-Grabowski Tomasz 
Published: October 2018

Purpose
The purpose of this paper is to investigate the feasibility of solving an integrated flight scheduling, fleet assignment and crew pairing problem for an on-demand service using a small, up to 19-seater, aircraft.

Design/methodology/approach
Evolutionary algorithm is developed to solve the problem. Algorithm design assumes indirect solution representation that allows to evaluate partially feasible solutions only and speed up calculations. Tested algorithm implementation takes advantage of the graphic processing unit.

Findings
Performed tests confirm that the algorithm can successfully solve the defined integrated scheduling problem.

Practical implications
The presented algorithm allows to optimise on-demand transport service operation within minutes.

Social implications
Optimisation of operation cost contributes to better accessibility of transport.

Originality/value
The presented integrated formulation allows to avoid sub optimal solutions that are results of solving sequential sub problems. Indirect representation and evaluation strategy can be applied to speed up calculations in other problems as well.
Keeping twin turbocharged engine power at flight altitudes
Authors: Khodaparast Mohammad Reza , Agha Seyed Mirza Bozorg Mohsen , Kheradmand Saeid 
Published: October 2018

Purpose
The purpose of this paper is the selection and arrangement of turbochargers set for internal combustion engine which could keep engine power in an altitude of up to 12.2 km above sea level.

Design/methodology/approach
In the current research, the target engine, a one-dimensional four-stroke 1,600 cc piston engine has been simulated and the manufacturer’ results have been validated. Depending on engine size, three proper types of Garret turbochargers GT30, GT25 and GT20 were selected for this engine. Then, the engine and a combination of two turbochargers have been modeled one-dimensionally. A control system was used for regulation of different pressure ratios between the two turbochargers.

Findings
The parametric analysis shows that using the combination of GT20, GT30 turbochargers with a properly controlled pressure ratio leads to a constant output power with little changes at different altitudes which enable achieving an altitude of 12.2 km for the target engine.

Practical implications
Adaptation of the internal combustion engine with a twin turbocharger using one-dimensional modeling.

Originality/value
The one-dimensional analysis provided an overall picture of the effective performance of turbochargers functioning in different altitudes and loads. It presents a new method for adopting of turbochargers set with internal combustion engines for propulsion medium-altitude aircraft.
Does a high women quota in supervisory boards influence firm success?
Authors: Binder Bettina C.K. 
Published: October 2018

PurposeThe purpose of this paper is to investigate the relationship between the success of the 50 EURO STOXX companies as measured by the earnings before taxes (EBT) and the percentage of female members on their supervisory boards.Design/methodology/approachThe paper relies on data extracted from the annual reports of the 50 EURO STOXX companies in 2015 and from financial websites.FindingsThe paper provides the existence of a weak correlation between companies’ performance as measured by EBT and the percentage of women on supervisory boards.Research limitations/implicationsThis study has two main limitations: first, a single key performance indicator was used to measure firms’ success; and second, the study offers insights related only to the year 2015. The analysis could be extended over a larger time span while some other variables could be considered in a more holistic approach.Practical implicationsThe paper raises awareness that there is much to be done with regard to the presence of women on boards, and readers, investors and business owners gain an insight on the business environment and women active on European corporate boards.Originality/valueBy concentrating on the companies of the EURO STOXX 50 Index, the study offers a good image of the European business environment.
Multi-objective optimization of the dimple/protrusion channel with pin fins for heat transfer enhancement
Authors: Luo Lei , Du Wei , Wang Songtao , Wu Weilong , Zhang Xinghong 
Published: October 2018

PurposeThe purpose of this paper is to investigate the optimal geometry parameters in a dimple/protrusion-pin finned channel with high thermal performance.Design/methodology/approachThe BSL turbulence model is used to calculate the flow structure and heat transfer in a dimple/protrusion-pin finned channel. The optimization algorithm is set as Non-dominated Sorting Genetic Algorithm II (NSGA-II). The high Nusselt number and low friction factor are chosen as the optimization objectives. The pin fin diameter, dimple/protrusion diameter, dimple/protrusion location and dimple/protrusion depth are applied as the optimization variables. An in-house code is used to generate the geometry model and mesh. The commercial software Isight is used to perform the optimization process.FindingsThe results show that the Nusselt number and friction factor are sensitive to the geometry parameters. In a pin finned channel with a dimple, the Nusselt number is high at the rear part of the dimple, while it is low at the upstream of the dimple. A high dissipative function is found near the pin fin. In the protrusion channel, the Nusselt number is high at the leading edge of the protrusion. In addition, the protrusion induces a high pressure drop compared to the dimpled channel.Originality/valueThe originality of this paper is to optimize the geometry parameters in a pin finned channel with dimple/protrusion. This is good application for the heat transfer enhancement at the trailing side for the gas turbine.
A strategy for large-scale scalar advection in large eddy simulations that use the linear eddy sub-grid mixing model
Authors: Arshad Salman , Kong Bo , Kerstein Alan , Oevermann Michael 
Published: October 2018

Purpose
The purpose of this numerical work is to present and test a new approach for large-scale scalar advection (splicing) in large eddy simulations (LES) that use the linear eddy sub-grid mixing model (LEM) called the LES-LEM.

Design/methodology/approach
The new splicing strategy is based on an ordered flux of spliced LEM segments. The principle is that low-flux segments have less momentum than high-flux segments and, therefore, are displaced less than high-flux segments. This strategy affects the order of both inflowing and outflowing LEM segments of an LES cell. The new splicing approach is implemented in a pressure-based fluid solver and tested by simulation of passive scalar transport in a co-flowing turbulent rectangular jet, instead of combustion simulation, to perform an isolated investigation of splicing. Comparison of the new splicing with a previous splicing approach is also done.

Findings
The simulation results show that the velocity statistics and passive scalar mixing are correctly predicted using the new splicing approach for the LES-LEM. It is argued that modeling of large-scale advection in the LES-LEM via splicing is reasonable, and the new splicing approach potentially captures the physics better than the old approach. The standard LES sub-grid mixing models do not represent turbulent mixing in a proper way because they do not adequately represent molecular diffusion processes and counter gradient effects. Scalar mixing in turbulent flow consists of two different processes, i.e. turbulent mixing that increases the interface between unmixed species and molecular diffusion. It is crucial to model these two processes individually at their respective time scales. The LEM explicitly includes both of these processes and has been used successfully as a sub-grid scalar mixing model (McMurtry et al., 1992; Sone and Menon, 2003). Here, the turbulent mixing capabilities of the LES-LEM with a modified splicing treatment are examined.

Originality/value
The splicing strategy proposed for the LES-LEM is original and has not been investigated before. Also, it is the first LES-LEM implementation using unstructured grids.
Hotel-like hospital rooms’ impact on patient well-being and willingness to pay
Authors: Suess Courtney , Mody Makarand Amrish 
Published: October 2018

Purpose
The study aims to examine how features that foster a sense of control, create positive distractions and provide access to social support influence patients’ well-being and, subsequently, their likelihood to choose hotel-like hospital rooms and their willingness to pay higher out-of-pocket expenses for such rooms. While there is increasing evidence to suggest the importance of the provision of hospitality in healthcare settings, research on these developments remains under-represented, particularly in the hospitality literature. In response, the present study builds on Ulrich’s (1991) theory of supportive design to examine patient responses to hotel-like features in a hospital room.

Design/methodology/approach
Using data from a survey of 406 patients, the authors used structural equation modeling to test the model.

Findings
Consistent with supportive design principles, the infusion of hotel-like features that foster a sense of control for patients, create positive distractions and provide access to social support was found to positively impact patients’ physical and mental well-being, which, in turn, increased their likelihood to choose a hospital room with hotel-like features and their willingness to pay for such rooms.

Practical Implications
Findings attest to the need for healthcare providers to make the necessary investment in hotel-like features and to leverage the communicative power of these environmental cues. Social support in the form of hospitality-trained and certified healthcare staff was found to be the most important hotel-like feature, which also presents significant commercial opportunities for hospitality companies and professionals.

Originality Value
The study represents one of the first attempts to empirically develop a structured model to examine the infusion of hospitality into healthcare. It provides researchers with a theoretically supported framework for future inquiry into the domain. It also makes a significant contribution to advancing the research on patient well-being in healthcare settings and demonstrates the importance of hospitality to such endeavors.
Hotel performance and research streams: a network cluster analysis
Authors: Sainaghi Ruggero , Baggio Rodolfo , Phillips Paul , Mauri Aurelio G. 
Published: October 2018

PurposeThis paper aims to provide a review of hotel performance within the hospitality and tourism research domain. The authors use network analysis to examine two research questions. The first relates to ascertaining general trends within the hotel performance literature, and the second focuses on identifying the salient streams and sub-topics.Design/methodology/approachArticles were selected according to three criteria: keywords, journals and year of publication. The analysis embraces 20 years (1996-2015). These choices assure a wide coverage of the literature. Using these three criteria, the sample includes 1,155 papers. For the analysis, the authors created a network of papers designated as nodes, and the citations among the papers as links. A network approach recognizes the internal structure of the network by identifying groups of nodes (papers) that are more densely connected between themselves than to other nodes within the network (modules, clusters or communities).FindingsThe authors found 761 papers that were “connected” studies within the network. By contrast, 34 per cent of the sample (394 papers) consists of “unconnected” studies. Excluding outliers, the net sample was 734 articles. The authors identify 14 clusters, which they break down into several sub-topics. The authors conclude by providing some conclusions regarding trends and future research directions. With regards to salient topics, cross-citation and network analysis provide a detailed picture of where the literature comes from and where it currently stands. Conclusions are articulated at the theoretical and empirical levels.Originality/valueCompared with previous hotel performance reviews, the approach followed by this study enables the discovery of an analytical research map, which is able to identify both clusters and sub-topics populating each segment. Researchers are able to position their work and identify issues that are in growth and decline.
Brand satisfaction
Authors: Nysveen Herbjørn , Oklevik Ove , Pedersen Per Egil 
Published: October 2018

Purpose
This paper aims to examine the influence of a brand’s innovativeness and green image on customers’ sensory, affective, cognitive, relational and behavioral brand experience and, through that, on brand satisfaction.

Design/methodology/approach
To collect primary data, the study used a list of 1,754 e-mail addresses from a hotel in Norway. Of the invited respondents, 283 completed the questionnaire.

Findings
The study shows positive influences of perceived brand innovativeness and green image on the experience dimensions. The influences of the brand experience dimensions on brand satisfaction are mixed. The results indicate that the brand experience dimensions partially mediate the influences of perceived brand innovativeness and green image on brand satisfaction. The study also shows a positive influence of perceived brand innovativeness on perceived green image.

Practical implications
The paper highlights the importance of carefully managing brands’ innovativeness and green image to improve brand experiences and satisfaction with the hotel.

Originality/value
Few studies exist on hotel brand experience, and therefore, future studies should identify antecedents and consequences of hotel brand experience (King, 2017; Khan and Rahman, 2017). This paper examines the role of hotel brand experiences with an explicit focus on the antecedents of such experiences.