bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surface engineering and applications of nanodiamonds in cancer treatment and imaging
Authors: Lai H. , Stenzel M. H. , Xiao P. 
Published: June 2019

Nanodiamonds (NDs) are emerging as a promising platform for theranostic particles because they unite a spectrum of important properties into a single agent, including facile synthesis, small size, inertness, rich surface functional groups, biocompatibility, stable fluorescence and long fluorescence lifetime. These unique properties have stimulated the application of NDs in cancer treament and imaging. The majority of these applications rely on the rational engineering of the particle surface, as the surface plays a critical role in carrying bioactive molecules, resisting aggregation and constructing composite materials. In this review, recent developments of functionalising NDs for cancer treatment and imaging purposes are discussed. A brief introduction in the structure of NDs and properties of NDs will be given, followed by a summary of various surface functionalisation methods. The latter part is organised in three subsections: NDs coated with bioactive compounds, NDs coated with synthetic polymers and NDs/inorganic composites.
From in vitro to ex vivo: subcellular localization and uptake of graphene quantum dots into solid tumors
Authors: Kersting David , Fasbender Stefan , Pilch Rabea , Kurth Jennifer , Franken André , Ludescher Marina , Naskou Johanna , Hallenberger Angelika , Gall Charlotte von , Mohr Corinna J , Lukowski Robert , Raba Katharina , Jaschinski Sandra , Esposito Irene , Fischer Johannes C , Fehm Tanja , Niederacher Dieter , Neubauer Hans , Heinzel Thomas 
Published: June 2019

Abstract
Among various nanoparticles tested for pharmacological applications over the recent years, graphene quantum dots (GQDs) seem to be promising candidates for the construction of drug delivery systems due to their superior biophysical and biochemical properties. The subcellular fate of incorporated nanomaterial is decisive for transporting pharmaceuticals into target cells. Therefore a detailed characterization of the uptake of GQDs into different breast cancer models was performed. The demonstrated accumulation inside the endolysosomal system might be the reason for the particles’ low toxicity, but has to be overcome for cytosolic or nuclear drug delivery. Furthermore, the penetration of GQDs into precision-cut mammary tumor slices was studied. These constitute a far closer to reality model system than monoclonal cell lines. The constant uptake into the depth of the tissue slices underlines the systems’ potential for drug delivery into solid tumors.
Voltage waveform tailoring in radio frequency plasmas for surface charge neutralization inside etch trenches
Authors: Krüger Florian , Wilczek Sebastian , Mussenbrock Thomas , Schulze Julian 
Published: June 2019

Abstract
The etching of sub micrometer high-aspect-ratio (HAR) features into dielectric materials in low pressure radio frequency technological plasmas is limited by the accumulation of positive surface charges inside etch trenches. These are, at least partially, caused by highly energetic positive ions that are accelerated by the sheath electric field to high velocities perpendicular to the wafer. In contrast to these anisotropic ions, thermal electrons typically reach the electrode only during the sheath collapse and cannot penetrate deeply into HAR features to compensate the positive surface charges. This problem causes significant reductions of the etch rate and leads to deformations of the features due to ion deflection, i.e. the aspect ratio is limited. Here, we demonstrate that voltage waveform tailoring can be used to generate electric field reversals adjacent to the wafer during sheath collapse to accelerate electrons towards the electrode to allow them to penetrate deeply into HAR etch features to compensate positive surface charges and to overcome this process limitation. Based on 1D3V particle-in-cell/Monte Carlo collision simulations of a capacitively coupled plasma operated in argon at 1 Pa, we study the effects of changing the shape, peak-to-peak voltage, and harmonics’ frequencies of the driving voltage waveform on this electric field reversal as well as on the electron velocity and angular distribution function at the wafer. We find that the angle of incidence of electrons relative to the surface normal at the wafer can be strongly reduced and the electron velocity perpendicular to the wafer can be significantly increased by choosing the driving voltage waveform in a way that ensures a fast and short sheath collapse. This is caused by the requirement of flux compensation of electrons and ions at the electrode on time average in the presence of a short and steep sheath collapse.
Preliminary study on relation between temperature, humidity and Night Sky Brightness in Yogyakarta
Authors: Pramudya Y , Budi K S , Okimustava  , Muchlas  
Published: June 2019

Abstract
The meteorological data is important to be collected especially at the observatory. Temperature and humidity are two parameters that can be monitored as part of meteorological data collections. The observatory site also need to be protected from light pollution. The light pollution level is usually measured by the value of Night Sky Brightness (NSB). In this paper, the relation between temperature, humidity and NSB will be studied. The temperature and humidity were measured by DHT11 Sensor that is assembled and monitored using Internet of Thing method. The NSB was measured using Sky Quality Meter. The measurements have been done in Observatorium UAD, Yogyakarta. The correlation calculation was employed to perform relationship analysis. The correlation value of temperature on NSB are in the range of -0.767 to 0.576. Hence, there is no particular pattern for the relationship between temperature and NSB. The correlation value of humidity on NSB are in the range of -0.812 to 0.977. Here, the humidity tend to have more number positive relationship to NSB. As the humidity increased, the NSB is increasing. However, the investigation on temperature and humidity data changes in particular duration of time measurement will give complete information about the relationship between temperature, humidity, and NSB. The conclusion can be used to create prediction model of NSB monitoring system.
Optical spectroscopy of nova ASASSN-17hx at Bosscha Observatory
Authors: Adhyaqsa A , Istiqomah A N , Ramadhan D G , Imaduddin I , Malasan H L , Arai A , Kawakita H 
Published: June 2019

Abstract
We report optical spectroscopic observations in 2017 at Bosscha Observatory on an interesting nova, ASASSN-17hx (Nova Sct 2017). The nova ASASSN-17hx was observed on July 26th, July 29th, July 31st, and August 14th. Based on the light curve, we propose that our spectroscopic observation of ASASSN-17hx was conducted during “iron curtain” phase. The observed spectra showed a strong Hα emission line and multiple emission lines of Fe II multiplets, which is typical for a Fe II type nova. However, since ASASSN-17hx was classified as a He/N type only few days after its outburst, it is suggested that the nova is actually a hybrid type nova. We will discuss the characteristic of ASASSN-17hx by analysing its expansion velocity, electron density, and evolution of the emission lines.
Applying Deep Neural Networks (DNN) for Measuring Photometric Redshifts from Galaxy Images: Preliminary Study
Authors: Syarifudin M R I , Hakim M I , Arifyanto M I 
Published: June 2019

Abstract
In the cosmological and extragalactic study, distance to a galaxy is an important parameter, by knowing the distance, we can find any other physical parameter such as mass, luminosity, star formation rate, and metallicity. By applying the specific cosmological model, we can measure a distance from the redshift. The exact redshift can only measure by using the spectroscopic technique (Doppler effect), but spectroscopic observation limited to brighter objects and numbers of objects in a single field of view (FoV). While photometric observation can capture fainter objects and more objects in a single FoV. Measurements of photometric redshift could have done by comparing the SED curves of the elliptical galaxy with known spectroscopic redshifts from other elliptical galaxies which we want to find the photometric redshift. Another method is to do linear or non-linear regression, by assuming the redshift is a function of magnitude in each band-pass filter. Therefore, we propose a technique that using full galaxy images in each measured bands and machine learning method for measuring photometric redshift. We pass entire multi-band galaxy images into the machine learning architecture to get an estimated redshift. In this work, we use galaxies images at 0 ≤ z ≤ 1 from SDSS DR 10 as the datasets and we use DenseNet, one of the Deep Neural Networks (DNN) architecture.
Radial Fourier transforms in exoplanetary imaging and potential uses at Timau National Observatory
Authors: Albanna H , Doelman D , Mumtahana F 
Published: June 2019

Abstract
Due to Fourier transforms nature between the field detected on the image and its corresponding input, astronomical imaging can be modelled mathematically. In exoplanetary imaging, we aim to detect exoplanets whose typical contrast are approximately one over a million times dimmer compared to their parent stars. Among the possible approaches to accomplish that is optical apodization, a technique to purposely modify the input signal profile such that the ‘Airy rings’ on the resulting image are suppressed while keeping the central brightness high. In the paper, we pedagogically describe this technique applying Fourier transforms of radially-symmetric functions; and investigate potential future uses at Timau National Observatory.
Preliminary Report of Light Pollution in Indonesia Based on Sky Quality Observation
Authors: Admiranto A. G. , Priyatikanto R. , Maryam S. , Ellyyani  , Suryana N. 
Published: June 2019

Abstract
We observed night sky quality in several LAPAN stations (Agam, Bandung, Pontianak, Sumedang, Garut, Pasuruan, and Biak) which were conducted from April until July 2018 using Unihedron Sky Quality Meter LU-DL type. Observational data from all of the observational points were then sent regularly to a centralized database for further use. Although most of the measurements were done in overcast conditions, we were able to determine the representative clear sky brightness statistically. The results showed that the light pollution level of the most of the stations are moderate (the values at Biak, Agam, Sumedang, and Pontianak are 20.0, 19.5, 19.6, and 17.7 mpsas respectively) and the stations which are located near or in cities are high (Bandung and Pasuruan with 17.1 and 18.0 mpsas, respectively). In a particular station (Garut) the light pollution is low (20.6 mpsas), so it is good to make this spot to be a location of astrotourism.
Atmospheric drag force on LAPAN-TUBSAT during geomagnetic storm 2015
Authors: Pratiwi N , Ikhsan M I 
Published: June 2019

Abstract
The purposes of this research are (1) determine the relationship between LAPAN-TUBSAT orbital elements and geomagnetic activity; (2) estimate daily drag acceleration; (3) determine the relationship between drag acceleration and geomagnetic activity. We used STK (System Tool Kit), python, and CCMC (Community Coordinated Modeling Center) interactive model to process the data. To calculate the drag acceleration, it takes data of satellite’s velocity that obtained from STK and atmospheric density. To generate atmospheric density, we used CCMC with MSISE-90 (Mass Spectrometer – Incoherent Scatter Extended 1990) and IRI (International Reference Ionosphere) atmospheric model. In addition, it takes the satellite’s position (latitude, longitude, and height – taken from STK) as input. On March 2015, geomagnetic storm index (daily Dst) had a minimum value of -105 nT on March 18, 2015. According to hourly Dst data, the minimum value of Dst reached -223 nT at 23:00 UT on March 17, 2015. Changes of orbital elements were influenced by geomagnetic storms through the Dst index. Maximum changes of semi-major axis, inclination, argument of perigee, and longitude of ascending node occurred on March 17-21, 2015 (geomagnetic storm period). Minimum change of eccentricity occurred on March 15-16, 2015 when Dst reached a maximum value. Atmospheric model is influenced most by solar conditions both during periods of calm or storm. Atmospheric density generated by MSISE-90 and IRI, both of them has 10−6 order difference. MSISE-90 is 10−16 while IRI 10−22. For MSISE-90, maximum drag acceleration reached 451,4416 m/hari2 occurred on March 17, 2015, along with a strong geomagnetic storm phenomenon. For IRI, the value of drag acceleration during peak geomagnetic storm (March 18, 2015) reached 0,000373 m/hari2 (close to the minimum value in March 2015). Drag acceleration of LAPAN-TUBSAT is linear to the Dst index with a correlation coefficient of -0,51.
Evaluation of the corrosion wear speed of different equipment in the water injection treatment plant
Authors: Dudu C , Ripeanu R G , Drumeanu A C , Dinita A , Lospa A M 
Published: June 2019

Abstract
The paper presents the results of the theoretical and experimental researches carried out for the evaluation of the corrosive rate of different equipment from water injection treatment plant used for water flooding. The degradation are occurring mainly at pipelines and connecting elements of the flotation skid, in the form of advanced corrosion wear because the water injection contains an inconsistent composition mixture of dissolved gases, hydrocarbons, solid particles. The manifestation of corrosion wear at the skid connections indicates that the mechanical-physical-chemical treatments used to reduce aggressiveness are not sufficiently effective. The tests were carried out on the corrosion specimens taken from the critical areas of the skid connections and using the different formation water taken from the same critical points. Corrosion rate was obtained through experimental tests made in accordance with ASTM G5-15 and ASTM G1-03. The results materialized in the form of an influence of corrosion inhibitor and temperature on the corrosion rate for different formation water samples.
Nonstandard teeth profile description and justification of precessional gear parameters selection
Authors: Bostan I , Dulgheru V 
Published: June 2019

Abstract
Teeth profiles have an important role in the efficient transformation of motion in the precessional transmissions. Multiple precessional gear theory, previously developed, did not take into consideration the influence of the diagram error of the linking mechanism in the processing device for gear wheel on the teeth profile. Functioning under the multiplication regime, these errors have major influence, which can lead to instant blocking of gear and to power losses. With this purpose, a thorough analysis was conducted on the motion development mechanism under multiplication, and on the teeth profile error generating source. On the basis of fundamental theory of multiple precessional gear, previously developed, a new gear with modified teeth profile and the technology for its industrial manufacturing was proposed and patented. The elaboration of the mathematic model of the modified teeth profile is based integrally on the mathematic model of teeth profile, previously developed by the authors. With this purpose it is necessary to present the detailed description of teeth profile without modification and, then, to present of the description of modified profile peculiarities.
Identification and viewing of singularities for a new type of 6

R_

SS parallel mechanism
Authors: Milica L , Năstase A , Andrei G 
Published: June 2019

Abstract
This paper presents a method for determining the singular configurations of a 6RSS parallel mechanism based on its kinematic model. The parallel mechanism consists of a fixed plate and a mobile platform connected through six independent kinematic chains. Each of the six kinematic chains has an actuating rotational joint and two spherical joints. The kinematic analysis is based on the kinematic screw method. The resultant motion can thus be represented by composing the kinematic screws of the component motions. Starting from the two Jacobian matrices of the kinematic model, the two types of singularities encountered in parallel mechanisms are identified. Singular configurations are determined by an algorithm which is further used to produce three-dimensional representations of the two matrices determinants. Also, with the same program, it is possible to accurately establish the existence or inexistence of a mechanism for a given position and orientation.
Command and Control vs self Management
Authors: Nicula D , Ghimiși S S 
Published: June 2019

Abstract
It’s estimated that in 2017 there were 111 billion lines of new software code generated by developers and most lines were written within a team. Producing software is a creative activity and therefore very different from mass-production lines, because each algorithm tries to solve a different problem. For many years, traditional system development life cycle has been used as the main algorithm for how programmer teams should work to deliver software products. Waterfall methodology is successfully used in simple, unchanging projects but its main drawback is how it handles change. Scrum encourages the creativity of each member of the team, allowing all of them to take on the role they want during the project. Each person can be a developer, a tester, a designer, depending on the responsibilities he takes between two sprints. Considering the diversity of IT projects, it makes sense to understand in what kind of projects we should use the Scrum methodology and where there is a need for more explicit management and control.
Virtual instrument for technical and economic standpoint evaluation of dimensional measurement methods and devices for the machined components finished products
Authors: Braun B C 
Published: June 2019

Abstract
The paper presents a research stage, within PhD Thesis, focused on critical analysis of the solutions for quality insurance in the production activity, standpoint dimensional inspection. The key was the programming of a flexible and efficient software environment, which will help the operator to make the proper decision on the best method and optimal means of dimensional measurement of various categories of fabricated components. It is practical one and it could be very important for productivity increasing, for low costs and also for finite products high quality. To accomplish this software application it were defined as inputs several criteria, like: inspection process timing, measuring precision, devices costs, process costs and energetic consumption. The most part of these criteria (process duration, measuring precision, devices costs) was possible to be established very properly, due to some previous analytical and empiric results, associated to several tested measuring devices
Model identification of dengue fever spreading using firefly algorithm and backpropagation neural network
Authors: Fitania S A , Damayanti A , Pratiwi A B 
Published: June 2019

Abstract
Dengue Fever is one of Indonesia’s well-known medical problems where the range spread territories have became more extensive alongside with mobility and population growth. Considering that a large number of population in East Java - Indonesia has been infected, the identification of Dengue Fever is needed in order to anticipate and minimalize the terrible possibilities that could happen. The aim of this research is to obtain the result of Dengue Fever spreading model identification using Firefly Algorithm and Back-propagation Neural Network. Back-propagation Neural Network identification is proposed to estimate the spreading of Dengue Fever based on actual data. The process begins with estimating the parameters using Firefly Algorithm then identifying the model using Back-propagation Neural Network. Based on the implementation and simulation on the Dengue Fever spreading data in East Java-Indonesia from January 2013 to December 2017, model was succesfully identified where the error value between estimated data and actual data was 0.0242.
Synthesis of Carbonated Hydroxyapatite Derived from Snail Shells (Pilla ampulacea): Effect of Carbonate Precursor to the Crystallographic Properties
Authors: Komang Januariyasa I , Yusuf Yusril 
Published: June 2019

Abstract
This study aimed to investigate the effect of the amount of carbonate in synthesis to the crystallography properties of carbonated-hydroxyapatite (CHAp) using the snail shells as the calcium source. Snail shells were cleaned, milled, and sintered at 1000°C for 4 hours to get CaO powder. CHAp synthesized by co-precipitation method. The molar ratio CO3
2-/PO4
3- was varied 0/6, 2/6, 3/6, and 6/6. Meanwhile, the molar ratio of Ca/P was kept at 1.67. After synthesis, the solution was aged, centrifugally washed, dried, and sintered at 400°C for 2 h in the air atmosphere. A scanning electron microscope (SEM) was used to observe the morphology of CHAp. An energy dispersive spectroscopy (EDS) was used to determine the chemical composition of CHAp. An X-Ray Diffractometer (XRD) was conducted to analyze the crystallography of CHAp. Fourier transform infrared (FT-IR) was used to evaluate the chemical structure of the CHAp. The XRD spectra of CHAp of all variations show they have apatite phase. There is no secondary phase observed in XRD spectra. The results of FTIR and EDS supported the XRD results. The increasing of carbonate amount in synthesis decreased the crystallinity and crystallite size of CHAp. The lattice parameter a-axis was decreased, but the lattice parameter c-axis was increased as the amount of carbonate increased in the synthesis process. The increasing of carbonate amount in synthesis decreases the crystallite size of CHAp. The results demonstrate that the amount of carbonate in synthesis affects the crystallography properties of CHAp.
Effect of Silver Substitution on Electrical Transport and Magnetoresistance of La0.8Ca0.2MnO3
Authors: Munazat Dicky Rezky , Kurniawan Budhy , Imaddudin Agung , Kamila Rina , Razaq Dhawud Sabilur 
Published: June 2019

Abstract
In this work, we have investigated the effect of silver substitution on electrical transport behavior and magnetoresistance of La0.8-
xAgxCa0.2MnO3 (x = 0 and 0.05). Preparation and study of structural and microstructure of both samples have been reported on previous work. Temperature-dependent resistivity has been measured at temperature range of 15-285 K with zero field cooling. Magnetoresistance effect has been measured at 15, 100, and 285 K with magnetic field up to 1 T. The electrical transport behavior of both samples are quite well described by a theory based on the Percolation model. The electrical conduction mechanism at low temperature can be explained by a theory based on Kondo-like spin-dependent scattering, electron-electron, electron–magnon, and electron-phonon scattering. It was found that silver substitution increases the metal-insulator transition temperature (TM-I) from 197.55 to 277.56 K, and Curie temperature (Tc
Mod) from 217.25 to 278.65 K. Moreover, the maximum magnetoresistance value of both samples was obtained at 15 K.