bluuebunny/crossref_metadata_2025_split huggingface dataset:
Not All Human Trafficking is Created Equal: Transnational Human Trafficking in the UK and Serbian News Media Texts—Narratological and Media Studies Approaches
Authors: Muždeka Nina 
Published: June 2018

AbstractThis chapter investigates the representation of transnational human trafficking in news texts in English and Serbian (published between 2000–2016 and 2003–2016 respectively) by adopting contemporary narrative and media theories. The identified narrative strategies and narrative elements (pertaining to the fabula, story, and text) not only shape the news texts, but also function as a semiotic code through which reality is itself constructed. In both sets of news texts, narratives as forms of representation prioritize particular aspects of human trafficking (e.g., use of official sources), while neglecting and/or completely excluding others (e.g., roots of human trafficking). The chapter draws attention to the logic behind such mechanisms that transform information into meaningful structures and thus influence the shaping of public perception and responses to this crime.
Whole‐Body Computed Tomography During Initial Management and Mortality Among Adult Severe Blunt Trauma Patients: A Nationwide Cohort Study
Authors: Tsutsumi Yusuke , Fukuma Shingo , Tsuchiya Asuka , Yamamoto Yosuke , Fukuhara Shunichi 
Published: June 2018

AbstractBackgroundWhole‐body computed tomography (WBCT) is increasingly being incorporated into the initial management of blunt trauma patients. Several observational studies have suggested that, compared to selective CT, WBCT is associated with lower mortality. In contrast, a randomized controlled trial found no significant difference in survival between patients undergoing WBCT compared to selective CT. Our objective was to confirm the association between WBCT and in‐hospital mortality among adult severe blunt trauma patients.
MethodsThis was a retrospective cohort study based on Japan Trauma Data Bank 2004–2015 registry data. The study population comprised adult severe blunt trauma patients with at least one abnormal vital sign: systolic blood pressure ≤100 mmHg, heart rate ≥120, respiratory rate ≥30 or ≤10, or Glasgow Coma Score ≤13. The primary outcome was in‐hospital mortality. To adjust for both measured and unmeasured confounders, we performed instrumental variable (IV) analysis to compare the in‐hospital mortality of patients undergoing WBCT with those undergoing selective CT.ResultsOf 40,435 patients who were eligible for this study, 19,766 (48.9%) patients underwent WBCT. The proportion of patients undergoing WBCT significantly increased during the study period, from 10.7% in 2004 to 59.6% in 2015. Primary IV analysis showed a significant association between WBCT and lower in‐hospital mortality (odds ratio 0.84, 95% confidence interval 0.72–0.98).ConclusionsWBCT can be beneficial in patients with blunt trauma which has compromised vital signs. These findings from a nationwide study suggest that physicians should consider WBCT for blunt trauma patients when warranted by vital signs.
Success in a Failed Campaign: The French Refugees of Jersey and the Making of an Abstract “Right to Refuge”
Authors: Shaw Caroline 
Published: June 2018

AbstractHistories of human rights tend to focus on defining moments, clear instances of universalism triumphant. If we hold to this model, the 1855 campaign on behalf of French republican—or democratic socialist—refugees was a failure. The refugees, expelled from Jersey in the Channel Islands for a libel of the queen, were little liked, and the campaign on their behalf did not yield the desired results, enabling them to return to Jersey. Yet, as this article argues, the failed campaign ought to be judged by different measures than the campaigners’ desired results, for we see in it the dynamics of refugee crises down to the present: an ongoing attempt to make refuge a universal norm in the face of persistent doubt that the refugees in question were “worthy” of staying. The French refugees and their supporters drew public attention to a right that they claimed derived from precedent, the British constitution, and moral principle. Though they did not succeed in their immediate cause, campaigners drew the admission even from naysayers that there was a “right to refuge”—but one the naysayers would not agree must be upheld at all costs.
IAMBLICHUS’ EPISTLES, FOURTH-CENTURY PHILOSOPHICAL AND POLITICAL EPISTOLOGRAPHY AND THE NEOPLATONIC CURRICULA AT ATHENS AND ALEXANDRIA
Authors: Marcos Moysés 
Published: June 2018

As a literary genre and practice, philosophical and political epistolography seems to have been alive and well in the fourth-century Roman empire. We have fragments of twenty letters of the late third- and early fourth-centuryc.e. Platonist (Neoplatonist to us) philosopher Iamblichus of Chalcis (which are preserved in the early fifth-century Ioannes Stobaeus’Anthologium[ = Flor.]) to former students and other contemporaries, some of whom appear to have been imperial officeholders (see Appendix); theEpistle to Himeriusof Sopater the Younger (which is partially preserved in Stobaeus, 4.5.51–60, in sequential extracts; this Sopater is the homonymous son of the philosopher who had been Iamblichus’ student) to his brother Himerius on the latter's assumption of an unknown governorship (ἡγεμονία) in the East, probably sometime in the 340s or 350s (and so under the Emperor Constantius II); the Emperor Julian'sEpistle to Themistius, which was likely written and publishedc.December 361/early 362; and theEpistle to Julianof the Aristotelian philosopher Themistius on proper rule (preserved in two Arabic manuscripts from the eleventh and fourteenth/fifteenth centuries), which seems to have been a response, in part, to Julian'sEpistle to Themistiusand perhaps was written to the emperor when both men likely resided in Constantinople at the same time. These philosophical and political letters are but a few examples from this period. All four authors mentioned above, who are representative of intellectual life in the East during the fourth century, produced epistles which reflect Greek political theory in a Roman imperial context.
Treatment of unilateral vocal fold paralysis with ansa cervicalis to recurrent nerve anastomosis in a young adolescent: European case report
Authors: van den Boer C , Wiersma A L , Marie J P , van Lith-Bijl J T 
Published: June 2018

AbstractBackgroundLaryngeal re-innervation in paediatric unilateral vocal fold paralysis is a relatively new treatment option, of which there has been little reported experience in Europe.MethodsIn this European case report of a 13-year-old boy with dysphonia secondary to left-sided unilateral vocal fold paralysis after cardiac surgery, the patient underwent re-innervation using an ansa cervicalis to recurrent laryngeal nerve transfer, in combination with fat augmentation, after 12 years of nerve denervation. Perceptual analysis data, and acoustic and laryngoscopy recordings were acquired pre-operatively, and at one and two years post-operatively.ResultsThe patient's perceptual voice quality was improved. He experienced subjective improvement and is very satisfied with the result. As expected, laryngoscopy at one and two years after surgery showed no physiological mobility of the vocal fold concerned, but improved closure during phonation was achieved. Electromyography showed evidence of re-innervation.ConclusionLaryngeal re-innervation could be considered as a treatment option for unilateral vocal fold paralysis in children and adolescents, even after a long-term delay.
Interacting Circles of Educational Desire in Rural Odisha: Students, schools, state
Authors: BOWEN ZAZIE 
Published: June 2018

AbstractChildren from rural Odishan Scheduled Tribe and Scheduled Caste communities have an historically marginalized relation to schools and a corresponding greater involvement with informal education regimes and participation in everyday economic and cultural routines. Although radical state restructuring in recent decades makes rural school buildings more visible, inside the classrooms, students were often present and teachers absent. Drawing on ethnographic fieldwork, in Western Mayurbhanj, Odisha, I examine students’ engagement with school and argue that rural schools cannot be fully understood without examining the motivations of and interactions between three sets of stakeholders: state, local providers, and students. Further, the motivations, evaluations, and experiences of students deserve to be brought much more to the fore in light of their active roles in Mayurbhanj village schools and the significant effects of this involvement on both the nature of rural schools and the changes in rural blocks.
Karl Popper, Winston Churchill, and the Tradition of Liberty among the English-speaking Peoples
Authors: Espada João Carlos 
Published: June 2018

AbstractThis paper starts by recalling a conversation of the author, then a young student, with Karl Popper in 1988. Popper argued that there is a ‘British mystery’ among the English-speaking peoples: their deep love of liberty, combined with a deep sense of duty, which was epitomised in the 20th Century by Winston Churchill. This paper argues that Churchill was a representative of an old tradition that goes back to Magna Carta of 1215. At its core is the protection of liberty to enjoy decentralised and peaceful ways of life and the corresponding allergy to revolutions and to schemes of perfection centrally designed.
Transmission routes of influenza A(H1N1)pdm09: analyses of inflight outbreaks
Authors: Lei H. , Tang J. W. , Li Y. 
Published: June 2018

AbstractKnowledge about the infection transmission routes is significant for developing effective intervention strategies. We searched the PubMed databases and identified 10 studies with 14 possible inflight influenza A(H1N1)pdm09 outbreaks. Considering the different mechanisms of the large-droplet and airborne routes, a meta-analysis of the outbreak data was carried out to study the difference in attack rates for passengers within and beyond two rows of the index case(s). We also explored the relationship between the attack rates and the flight duration and/or total infectivity of the index case(s). The risk ratios for passengers seated within and beyond the two rows of the index cases were 1.7 (95% confidence interval (CI) 0.98–2.84) for syndromic secondary cases and 4.3 (95% CI 1.25–14.54) for laboratory-confirmed secondary cases. Furthermore, with an increase of the product of the flight duration and the total infectivity of the index cases, the overall attack rate increased linearly. The study indicates that influenza A(H1N1)pdm09 may mainly be transmitted via the airborne route during air travel. A standardised approach for the reporting of such inflight outbreak investigations would help to provide more convincing evidence for such inflight transmission events.
Patent ductus arteriosus in preterm infants born before 30 weeks’ gestation: high rate of spontaneous closure after hospital discharge
Authors: Romagnoli Vittorio , Pedini Annalisa , Santoni Monica , Scutti Grazia , Colaneri Massimo , Pozzi Marco , Cogo Paola E. , Carnielli Virgilio P. 
Published: June 2018

AbstractAimThe aim of this study was to determine the spontaneous closure rate of patent ductus arteriosus at a 2-year follow-up, following failed medical therapy and beyond initial hospital discharge, and to evaluate in-hospital spontaneous or pharmacological closure rates.Materials and methodsA retrospective evaluation was conducted in a cohort of preterm infants admitted to the Neonatal ICU of Ancona between January, 2004 and June, 2013. Inclusion criteria were gestational age between 24+0 and 29+6 weeks or birth weight <1250 g; admission within 48 hours from birth; and discharge alive from hospital. All infants received routine heart ultrasound between 48 and 72 hours of life. Haemodynamically significant patent ductus arteriosus was defined as a duct diameter >1.5 mm, a left atrium-to-aorta ratio >1.4, and/or reversal of end-diastolic flow in the aorta >30% of the anterograde. First-line treatment was intravenous ibuprofen. Intravenous indomethacin was used if ibuprofen failed. Surgical ligation was considered in haemodynamically significant patent ductus arteriosus after medical treatment.ResultsA total of 593 infants met the inclusion criteria, and patent ductus arteriosus was diagnosed in 317 (53.4%). Among them, 283 (89.3%) infants had haemodynamically significant patent ductus arteriosus, with pharmacological closure achieved in 228 (80.6%) infants and surgical ligation performed in 20 (7.1%). Follow-up at 24 months was available for 39 (81.3%) of 48 infants with patent ductus arteriosus at the hospital discharge: 36 (92.3%) underwent spontaneous closure, two (5.1%) underwent surgical ligation, and one (2.6%) had a patent ductus arteriosus.DiscussionA significant number of patent ductus arteriosus that fail pharmacological closure undergo spontaneous closure by the age of 2 years. This information should be taken into account when considering surgery or additional attempts of pharmacological closure.
Practical Privacy: Report from the GDPR World
Authors: Doe Susan 
Published: June 2018

AbstractIn this article Susan Doe reports from the perspective of the law firm sector on the progress towards the introduction of the General Data Protection Regulation that became automatically ‘live’ on 25 May 2018. She provides an introduction to the Regulation, highlights some practicalities for law firms when considering compliance with GDPR and offers a ‘to do’ list with reference to the record of data processing, training needs, security, and contracts and documentation. She also provides advice on what should be considered especially in respect of client demands.
The World Turned Upside Down: Reaching Out to Law Libraries in Sierra Leone
Authors: Bracey Sarah , Simmonds Tony 
Published: June 2018

AbstractThis article, by Sarah Bracey and Tony Simmonds, explores professional and cultural challenges confronting two BIALL members involved in a project to enhance law library services in Freetown, Sierra Leone. It considers approaches to developing effectual supportive partnerships in a developing country context where the legal information ecosystem and provision of resource differ to an extent that all but inverts the familiar working world. The article traces the boundaries of what change is feasible in such a context, cautioning against over-ambition and advocating areas for future focus around staffing, co-ordination of donation programmes and digitisation of primary materials.
Low‐Frequency Seismic Noise Characteristics From the Analysis of Co‐Located Seismic and Pressure Data
Authors: Tanimoto Toshiro , Wang Jiong 
Published: June 2018

AbstractWe analyze the characteristics of seismic noise generated by surface pressure changes, using co‐located seismic and pressure data from the USArray Transportable Array for the entire year of 2014. We compare pressure and seismic signals at frequencies of 0.01 and 0.02 Hz and model their main characteristics. At these frequencies, vertical and horizontal seismic noise can be explained by the formulas SZ = A * Sp + NZ and SH = B * Sp + NH, where SZ and SH are the power spectral densities of vertical and horizontal ground velocities (sum of two horizontal components), Sp is the power spectral density of pressure, and NZ and NH are constant terms. We first determine A and B from the high pressure range (Sp > 10 Pa2/Hz) in which NZ and NH are small. From A and B, we then determine the near‐surface rigidity and pressure wave speed. This rigidity is modified from true rigidity by a factor (λ + μ)/(λ + 2 μ); this factor is about 0.7 for typical crustal rocks but approaches 1 near the Earth's surface. To estimate true rigidity, empirical formulas that relate density and seismic velocities are needed. Once A and B are determined, NZ and NH are determined. NZ and rigidity of the subsurface determine a threshold pressure in vertical data. NH is generally small but at some stations it changes seasonally and creates separate branches in plots of pressure versus seismic velocity. This may explain why seismic‐noise reduction approaches using co‐located pressure data often fail to work for horizontal data but usually work well for vertical data.
ATR is required to complete meiotic recombination in mice
Authors: Pacheco Sarai , Maldonado-Linares Andros , Marcet-Ortega Marina , Rojas Cristina , Martínez-Marchal Ana , Fuentes-Lazaro Judit , Lange Julian , Jasin Maria , Keeney Scott , Fernández-Capetillo Oscar , Garcia-Caldés Montserrat , Roig Ignasi 
Published: June 2018

AbstractPrecise execution of recombination during meiosis is essential for forming chromosomally-balanced gametes. Meiotic recombination initiates with the formation and resection of DNA double-strand breaks (DSBs). Cellular responses to meiotic DSBs are critical for efficient repair and quality control, but molecular features of these remain poorly understood, particularly in mammals. Here we report that the DNA damage response protein kinase ATR is crucial for meiotic recombination and completion of meiotic prophase in mice. Using a hypomorphic Atr mutation and pharmacological inhibition of ATR in vivo and in cultured spermatocytes, we show that ATR, through its effector kinase CHK1, promotes efficient RAD51 and DMC1 assembly at RPA-coated resected DSB sites and establishment of interhomolog connections during meiosis. Furthermore, our findings suggest that ATR promotes local accumulation of recombination markers on unsynapsed axes during meiotic prophase to favor homologous chromosome synapsis. These data reveal that ATR plays multiple roles in mammalian meiotic recombination.
Fern genomes elucidate land plant evolution and cyanobacterial symbioses
Authors: Li Fay-Wei , Brouwer Paul , Carretero-Paulet Lorenzo , Cheng Shifeng , de Vries Jan , Delaux Pierre-Marc , Eily Ariana , Koppers Nils , Kuo Li-Yaung , Li Zheng , Simenc Mathew , Small Ian , Wafula Eric , Angarita Stephany , Barker Michael S. , Bräutigam Andrea , dePamphilis Claude , Gould Sven , Hosmani Prashant S. , Huang Yao-Moan , Huettel Bruno , Kato Yoichiro , Liu Xin , Maere Steven , McDowell Rose , Mueller Lukas A. , Nierop Klaas G. J. , Rensing Stefan A. , Robison Tanner , Rothfels Carl J. , Sigel Erin M. , Song Yue , Timilsena Prakash R. , Van de Peer Yves , Wang Hongli , Wilhelmsson Per K. I. , Wolf Paul G. , Xu Xun , Der Joshua P. , Schluepmann Henriette , Wong Gane K.-S. , Pryer Kathleen M. 
Published: June 2018

AbstractFerns are the closest sister group to all seed plants, yet little is known about their genomes other than that they are generally colossal. Here, we report on the genomes of Azolla filiculoides and Salvinia cucullata (Salviniales) and present evidence for episodic whole-genome duplication in ferns—one at the base of ‘core leptosporangiates’ and one specific to Azolla. One fern-specific gene that we identified, recently shown to confer high insect resistance, seems to have been derived from bacteria through horizontal gene transfer. Azolla coexists in a unique symbiosis with N2-fixing cyanobacteria, and we demonstrate a clear pattern of cospeciation between the two partners. Furthermore, the Azolla genome lacks genes that are common to arbuscular mycorrhizal and root nodule symbioses, and we identify several putative transporter genes specific to Azolla–cyanobacterial symbiosis. These genomic resources will help in exploring the biotechnological potential of Azolla and address fundamental questions in the evolution of plant life.
Sir-2.1 mediated attenuation of α-synuclein expression by Alaskan bog blueberry polyphenols in a transgenic model of Caenorhabditis elegans
Authors: Maulik Malabika , Mitra Swarup , Hunter Skyler , Hunstiger Moriah , Oliver S. Ryan , Bult-Ito Abel , Taylor Barbara E. 
Published: June 2018

AbstractMisfolding and accumulation of cellular protein aggregates are pathological hallmarks of aging and neurodegeneration. One such protein is α-synuclein, which when misfolded, forms aggregates and disrupts normal cellular functions of the neurons causing Parkinson’s disease. Nutritional interventions abundant in pharmacologically potent polyphenols have demonstrated a therapeutic role for combating protein aggregation associated with neurodegeneration. The current study hypothesized that Alaskan bog blueberry (Vaccinum uliginosum), which is high in polyphenolic content, will reduce α-synuclein expression in a model of Caenorhabditis elegans (C. elegans). We observed that blueberry extracts attenuated α-synuclein protein expression, improved healthspan in the form of motility and restored lipid content in the transgenic strain of C. elegans expressing human α-synuclein. We also found reduced gene expression levels of sir-2.1 (ortholog of mammalian Sirtuin 1) in blueberry treated transgenic animals indicating that the beneficial effects of blueberries could be mediated through partial reduction of sirtuin activity. This therapeutic effect of the blueberries was attributed to its xenohormetic properties. The current results highlight the role of Alaskan blueberries in mediating inhibition of sir-2.1 as a novel therapeutic approach to improving pathologies of protein misfolding diseases. Finally, our study warrants further investigation of the structure, and specificity of such small molecules from indigenous natural compounds and its role as sirtuin regulators.
Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development
Authors: Astone Matteo , Lai Jason Kuan Han , Dupont Sirio , Stainier Didier Y. R. , Argenton Francesco , Vettori Andrea 
Published: June 2018

AbstractAs effectors of the Hippo signaling cascade, YAP1 and TAZ are transcriptional regulators playing important roles in development, tissue homeostasis and cancer. A number of different cues, including mechanotransduction of extracellular stimuli, adhesion molecules, oncogenic signaling and metabolism modulate YAP1/TAZ nucleo-cytoplasmic shuttling. In the nucleus, YAP1/TAZ tether with the DNA binding proteins TEADs, to activate the expression of target genes that regulate proliferation, migration, cell plasticity, and cell fate. Based on responsive elements present in the human and zebrafish promoters of the YAP1/TAZ target gene CTGF, we established zebrafish fluorescent transgenic reporter lines of Yap1/Taz activity. These reporter lines provide an in vivo view of Yap1/Taz activity during development and adulthood at the whole organism level. Transgene expression was detected in many larval tissues including the otic vesicles, heart, pharyngeal arches, muscles and brain and is prominent in endothelial cells. Analysis of vascular development in yap1/taz zebrafish mutants revealed specific defects in posterior cardinal vein (PCV) formation, with altered expression of arterial/venous markers. The overactivation of Yap1/Taz in endothelial cells was sufficient to promote an aberrant vessel sprouting phenotype. Our findings confirm and extend the emerging role of Yap1/Taz in vascular development including angiogenesis.