bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inquérito Policial: um instrumento eficiente e indispensável à investigação
Authors: Perazzoni Franco , Silva Wellington Clay Porcino 
Published: June 2018

O recrudescimento da violência, nestes últimos anos, conduziu-nos a um cenário de intensa desconfiança no Sistema de Justiça Criminal, sobretudo na Segurança Pública. Para alguns, a verdadeira panaceia universal dos graves problemas de Segurança Pública brasileiros seria tão somente a adopção de modelos estrangeiros de estrutura policial e, por conseguinte, de investigaçãocriminal, como se o avanço da criminalidade não fosse causado pelas inúmeras mudanças sociais ocorridas ao longo das últimas décadas, mas, sim, pela opção histórica que o Brasil fez a respeito de seu modelo de investigação criminal. Ao longo deste estudo, procurar-se-á demonstrar que os resultados investigativos obtidos por forças policias dependem muito mais do tipo de crime investigado e da sociedade na qual tal corporação se encontra inserida do que do modelode investigação adotado. Verificar-se-á, também, que no Brasil, a despeito das inúmeras críticas, diversas unidades de polícia judiciária têm obtido resultados expressivos, em patamares até superiores ao de polícias estrangeiras, consideradas de referência. Ademais, veremos que, para além do aspecto qualitativo, o inquérito policial brasileiro, devido à natureza imparcial da autoridade que o preside, isto é, o delegado de polícia, é aquele que melhor se adequa a um processo penal verdadeiramente garantista, sem descuidar da necessária proteção à sociedade.
Proses Kewirausahaan dalam Motivasi Pencapaian dan Intensi “E-Preneurs” Mahasiswa Bisnis dan Manajemen
Authors: Nelloh Liza Agustina Maureen 
Published: June 2018

Di Indonesia, baru ada sedikit bukti nyata terjadinya Timmons Model yang muncul bersamaan dengan rasa kebutuhan akan prestasi sebagai prediktor dorongan membuka bisnis online atau disebut “E-preneur”. Penelitian sebelumnya mengungkapkan bahwa mahasiswa menilai pendidikan kewirausahaan sebagai hal yang negatif. Oleh karena itu, penelitian kali ini akan menguji variabel laten secara bersamaan dalam dimensi Timmons Model yang dikombinasikan dengan kebutuhan akan prestasi (Need for achievement) dalam menciptakan “E-preneur” Intention. Penelitian ini menggunakan metode Partial Least Square (PLS) dan juga purposive sampling dalam survey kepada 106 mahasiswa bisnis dan manajemen di Jakarta dan Bandung. Hasil penelitian ini menunjukkan bahwa opportunity berpengaruh positif pada need for achievement dan intensi berwirausaha di bidang online, web dan aplikasi (E-preneur). Kemudian, entrepreneurial team memiliki pengaruh positif dalam menciptakan dorongan untuk menjadi “E-preneur” dan tidak signifikan terhadap need for achievement. Hasil penelitian ini menunjukkan bahwa universitas berbasis kewirausahaan harus mengadakan semakin banyak kegiatan eksperiensial seperti pinjaman kredit lunak dan presentasi langsung (direct pitching) dengan investor yang sebenarnya.
Antithrombotic medication and bleeding risk in patients with cerebral cavernous malformations: a cohort study
Authors: Bervini David , Jaeggi Christian , Mordasini Pasquale , Schucht Philippe , Raabe Andreas 
Published: June 2018

OBJECTIVECerebral cavernous malformations (CCMs) are frequently diagnosed vascular abnormalities. The hemorrhagic risk associated with the use of long-term antithrombotic medication (ATM) in patients with CCMs is a matter of controversy. The aim of this study was to determine the hemorrhagic risk associated with ATM use in patients diagnosed with one or more CCMs.METHODSDemographic, clinical, treatment, and ATM-related information on patients diagnosed with one or more CCMs at a single institution over more than 34 years was retrospectively recorded. Univariate and multivariate descriptive and survival analyses were used to assess potential risk factors associated with CCM-related hemorrhage at presentation and during follow-up (first or subsequent hemorrhage).RESULTSA total of 408 patients were included in the analysis and 492 CCMs were followed up after diagnosis, for a total of 1616 lesion-years. Thirty-seven (7.5%) CCMs bled during follow-up, leading to an overall annual rate of CCM-related symptomatic hemorrhage of 2.3% (95% CI 1.7%–3.2%). Eighty-two patients harboring 91 CCMs (16.8%) were on ATM. When stratified for ATM, the annual rates of hemorrhage were 0.7% (95% CI < 0.01% to 4.2%) for the lesions in patients on ATM versus 2.5% (95% CI 1.8%–3.4%) for those not on ATM. ATM was not found to be associated with either an increased risk of CCM-related hemorrhage at presentation (p = 0.355) or an increased risk of CCM-related hemorrhage (first or subsequent hemorrhage) in multivariate descriptive (p = 0.912) and survival (p = 0.145) analyses.CONCLUSIONSThe use of ATM does not seem to be associated with an increased risk of hemorrhage in patients diagnosed with CCMs.
Glioblastoma with Oligodendroglioma Component (GBMO) in an adolescent: a case report
Authors: Rodrigues Amanda Lopes Maia , Do Nascimento Daniel Macedo , Sato Eduarda De Carvalho , Moreira Fernanda De Paula , Gadelha Maitê Silva Martins , Sampaio Paula Cíntia Machado , Martinoli Tarsila Stockler Ravaschieri , Lira Yan Garcia 
Published: June 2018

Background:Glioblastoma with oligodendroglioma component (GBMO) is a recently classified subtype of glioblastoma, which carries different clinical and prognostic outcomes, being frequently misdiagnosed. Both glioblastoma and GBMO are mainly seen in older ages, such as the 5th and 6th decades of life, being an extremely rare occurrence in children or adolescents and more frequent in male patients.
Case report: A 15-year-old girl, presented with history of daily headache, not relieved by painkillers, vomiting, blurred vision and strabismus. Magnetic resonance imaging of the brain revealed expansive tumour on left temporo-occipital lobe. Patient was submitted to intracranial exeresis, along with histopathological examination: glial neoplasm with areas of pleomorphism, hyperchromatism, anaplasia, foci of oligodendroglial component, perinuclear halo and ramified capillaries, resembling oligodendroglioma, necrosis and intense mitotic activity. The immunohistochemical analysis revealed positive Glial Fibrillary Acidic Protein (GFAP), synaptophysin, Ki-67 (MindBomb E3 ubiquitin protein ligase 1 – MIB-1)and hyperexpression of Epidermal Growth Factor Receptor (EGFR), indicating GBMO. Subsequently, Fluorescence in situ Hybridization (FISH) showed 1p/19q codeletion and Isocitrate Dehydrogenase 1 (IDH 1) mutation, suggesting an oligodendroglioma component. Tumour resection was total and symptoms disappeared. Afterwards, she started adjuvant oral chemotherapy with temozolomide. Treatment was completed nine months after the diagnosis, with no greater symptoms or complications and complete remission.
Conclusion: GBMO must be considered as a possible diagnosis when confronted with a malignant glioma with oligodendroglial tumour component, independent of age or genre. Necrosis upon histopathological examination has a strong relation to shorter median overall survival. IDH mutation and 1p/19q codeletion should be analyzed by immunohistochemistry. Total tumour resection, with adjuvant treatment (chemotherapy with temozolomide and radiotherapy), increases benefits and improves prognosis.
Eccentric Black Hole Gravitational-wave Capture Sources in Galactic Nuclei: Distribution of Binary Parameters
Authors: Gondán László , Kocsis Bence , Raffai Péter , Frei Zsolt 
Published: June 2018

Abstract
Mergers of binary black holes on eccentric orbits are among the targets for second-generation ground-based gravitational-wave detectors. These sources may commonly form in galactic nuclei due to gravitational-wave emission during close flyby events of single objects. We determine the distributions of initial orbital parameters for a population of these gravitational-wave sources. Our results show that the initial dimensionless pericenter distance systematically decreases with the binary component masses and the mass of the central supermassive black hole, and its distribution depends sensitively on the highest possible black hole mass in the nuclear star cluster. For a multi-mass black hole population with masses between 5

M

⊙

and 80

M

⊙

, we find that between ∼43–69% (68–94%) of 30

M

⊙

–30

M

⊙

(10 M
⊙–10 M
⊙) sources have an eccentricity greater than 0.1 when the gravitational-wave signal reaches 10 Hz, but less than ∼10% of the sources with binary component masses less than 30

M

⊙

remain eccentric at this level near the last stable orbit (LSO). The eccentricity at LSO is typically between 0.005–0.05 for the lower-mass BHs, and 0.1–0.2 for the highest-mass BHs. Thus, due to the limited low-frequency sensitivity, the six currently known quasicircular LIGO/Virgo sources could still be compatible with this originally highly eccentric source population. However, at the design sensitivity of these instruments, the measurement of the eccentricity and mass distribution of merger events may be a useful diagnostic to identify the fraction of GW sources formed in this channel.
Properties of Decaying Plasma Turbulence at Subproton Scales
Authors: Olshevsky Vyacheslav , Servidio Sergio , Pucci Francesco , Primavera Leonardo , Lapenta Giovanni 
Published: June 2018

Abstract
We study the properties of plasma turbulence at subproton scales using kinetic electromagnetic three-dimensional simulations with nonidentical initial conditions. Particle-in-cell modeling of the Taylor–Green vortex has been performed, starting from three different magnetic field configurations. All simulations expose very similar energy evolution in which the large-scale ion flows and magnetic structures deteriorate and transfer their energy into particle heating. Heating is more intense for electrons, decreasing the initial temperature ratio and leading to temperature equipartition between the two species. A full turbulent cascade, with a well-defined power-law shape at subproton scales, is established within a characteristic turnover time. Spectral indices for magnetic field fluctuations in two simulations are close to α

B
≈ 2.9, and are steeper in the remaining case with α

B
≈ 3.05. Energy is dissipated by a complex mixture of plasma instabilities and magnetic reconnection and is milder in the latter simulation. The number of magnetic nulls, and the dissipation pattern observed in this case, differ from two others. Spectral indices for the kinetic energy deviate from magnetic spectra by ≈1 in the first simulation, and by ≈0.75 in two other runs. The difference between magnetic and electric slopes confirm the previously observed value of α

B
− α

E
≈ 2.
The Late-type Eclipsing Binaries in the Large Magellanic Cloud: Catalog of Fundamental Physical Parameters
Authors: Graczyk Dariusz , Pietrzyński Grzegorz , Thompson Ian B. , Gieren Wolfgang , Pilecki Bogumił , Konorski Piotr , Villanova Sandro , Górski Marek , Suchomska Ksenia , Karczmarek Paulina , Stepień Kazimierz , Storm Jesper , Taormina Mónica , Kołaczkowski Zbigniew , Wielgórski Piotr , Narloch Weronika , Zgirski Bartłomiej , Gallenne Alexandre , Ostrowski Jakub , Smolec Radosław , Udalski Andrzej , Soszyński Igor , Kervella Pierre , Nardetto Nicolas , Szymański Michał K. , Wyrzykowski Łukasz , Ulaczyk Krzysztof , Poleski Radosław , Pietrukowicz Paweł , Kozłowski Szymon , Skowron Jan , Mróz Przemysław 
Published: June 2018

Abstract
We present a determination of the precise fundamental physical parameters of 20 detached, double-lined, eclipsing binary stars in the Large Magellanic Cloud (LMC) containing G- or early K-type giant stars. Eleven are new systems; the remaining nine are systems already analyzed by our team for which we present updated parameters. The catalog results from our long-term survey of eclipsing binaries in the Magellanic Clouds suitable for high-precision determination of distances (the Araucaria Project). The V-band brightnesses of the systems range from 15.4 to 17.7 mag, and their orbital periods range from 49 to 773 days. Six systems have favorable geometry showing total eclipses. The absolute dimensions of all eclipsing binary components are calculated with a precision of better than 3%, and all systems are suitable for a precise distance determination. The measured stellar masses are in the range 1.4 to 4.6 M
⊙, and comparison with the MESA isochrones gives ages between 0.1 and 2.1 Gyr. The systems show an age–metallicity relation with no evolution of metallicity for systems older than 0.6 Gyr, followed by a rise to a metallicity maximum at age 0.5 Gyr and then a slow metallicity decrease until 0.1 Gyr. Two systems have components with very different masses: OGLE LMC-ECL-05430 and OGLE LMC-ECL-18365. Neither system can be fitted by a single stellar evolution isochrone, explained by a past mass transfer scenario in the case of ECL-18365 and a gravitational capture or hierarchical binary merger scenario in the case of ECL-05430. The longest-period system, OGLE LMC SC9_230659, shows a surprising apsidal motion that shifts the apparent position of the eclipses. This is a clear sign of a physical companion to the system; however, neither investigation of the spectra nor light-curve analysis indicates a third-light contribution larger than 2%–3%. In one spectrum of OGLE LMC-ECL-12669, we noted a peculiar dimming of one of the components by 65% well outside of the eclipses. We interpret this observation as arising from an extremely rare occultation event, as a foreground Galactic object covers only one component of an extragalactic eclipsing binary.
Measuring the Viewing Angle of GW170817 with Electromagnetic and Gravitational Waves
Authors: Finstad Daniel , De Soumi , Brown Duncan A. , Berger Edo , Biwer Christopher M. 
Published: June 2018

Abstract
The joint detection of gravitational waves (GWs) and electromagnetic (EM) radiation from the binary neutron star merger GW170817 ushered in a new era of multi-messenger astronomy. Joint GW–EM observations can be used to measure the parameters of the binary with better precision than either observation alone. Here, we use joint GW–EM observations to measure the viewing angle of GW170817, the angle between the binary’s angular momentum and the line of sight. We combine a direct measurement of the distance to the host galaxy of GW170817 (NGC 4993) of 40.7 ± 2.36 Mpc with the Laser Interferometer Gravitational-wave Observatory (LIGO)/Virgo GW data and find that the viewing angle is

degrees (90% confidence, statistical, and systematic errors). We place a conservative lower limit on the viewing angle of ≥13°, which is robust to the choice of prior. This measurement provides a constraint on models of the prompt γ-ray and radio/X-ray afterglow emission associated with the merger; for example, it is consistent with the off-axis viewing angle inferred for a structured jet model. We provide for the first time the full posterior samples from Bayesian parameter estimation of LIGO/Virgo data to enable further analysis by the community.
A first checklist of the Pteridophytes of Togo (West Africa)
Authors: Abotsi Komla , Kokou Kouami , Dubuisson Jean-Yves , Rouhan Germinal 
Published: June 2018

The present work proposes, for the first time, a study exclusively focused on the diversity of Pteridophytes in Togo.
The study was based on fieldwork that resulted in 869 new collections gathered between 2013 and 2017 in the country and on yet existing herbarium specimens kept at the Herbaria of Lomé and Paris. Thus, a total number of 1092 specimens collected throughout the country served as a basis for this work, to which were added the known, published occurrences of Pteridophytes for the country.
At the end of this study, a total diversity of 134 species belonging to 53 genera and 25 families and 12 orders were recorded and documented for the country. It results in 73 newly cited species for Togolese flora, including 61 spontaneous species. Lycopodiopsida (18 species) and Polypodiopsida (116 species) classes are both represented. The Polypodiales order is the most represented with 97 species. The Pteridaceae and Aspleniaceae families are the most diverse with 24 and 22 species respectively. Finally, notes were provided on species distribution at national level.
Vers un horizon post-capitaliste des dérives financières ?
Authors: Citton Yves 
Published: June 2018

Et si c’était dans les arcanes de la finance que prenait d’ores et déjà forme l’un des replis constitutifs du post-capitalisme ? Toute une série de penseurs (post ?-)marxistes, les plus stimulants parce que les plus hétérodoxes, se sont retrouvés récemment autour d’une analyse croisée de la notion de produits dérivés ( derivatives ) et des blockchains qui mérite de retenir toute notre attention. Cet article essaie d’en faire un survol rapide.
Le revenu universel, condition d’une finance post-capitaliste
Authors: Querrien Anne 
Published: June 2018

À la lecture de l’ensemble des contributions de cette majeure, Dériver la finance , quelques questions se posent. La blockchain qui consigne toutes les transactions au sein d’une communauté délocalisée de hackers, dit « mineurs », est-elle utilisable plus largement ? La recherche d’un surplus systématique peut-elle alimenter une multiplicité de valeurs ? Un revenu universel n’est-il pas une condition de base pour cet investissement tous azimuts dans la cyber-économie ? Comment se partage la formation nécessaire pour y participer ? Que permettent les nouvelles technologies par rapport à des tentatives plus anciennes de remise en cause de la valeur travail ? Comment ces nouvelles tentatives traitent-elles la valeur égalité présente au cœur de leurs ainées ?
La dynamique culturelle des formes de vie sociales
Authors: Nouët Clotilde 
Published: June 2018

Cet article a pour objectif de mettre à l’épreuve l’indétermination conceptuelle du terme « Lebensform » (forme de vie) dans la tradition philosophique allemande, en cherchant à montrer ce que l’on trouve dans la première Théorie critique, une lecture matérialiste des « formes de vie ». On se propose de la reconstruire, en rendant compte du concept dynamique de la culture élaboré par Horkheimer au cours des années 1930, dans un dialogue étroit, quoique implicite, avec le matérialisme marxien de L’Idéologie allemande .
Hemodynamics and Perfusion in Premature Infants During Transfusion
Authors: Weaver Barbara , Guerreso Kelsey , Conner E. Alexander , Russell Kendra , Vogel Robert , Rodriguez Mitch 
Published: June 2018

Background:
Premature infants may require packed red blood cell transfusions, but current guidelines lack empirical evidence and vary among institutions and prescribers.

Objective:
To compare the physiological changes in cardiovascular hemodynamics and oxygen delivery between premature infants with anemia who receive packed red blood cell transfusions and premature infants without anemia.

Methods:
The study was a prospective observational cohort investigation of 75 premature infants. Comparisons among the data were made before, during, and after transfusion in infants with anemia and over time in infants in the control group. In infants with anemia, feedings were withheld 12 hours before and after transfusions.

Results:
Electrical cardiometry and near-infrared spectroscopy measurements in premature infants with anemia revealed changes in hemodynamic parameters not detected by standard bedside monitoring. Statistically significant changes were seen before and after transfusions in cardiac output, fractional tissue oxygen extraction, heart rate variability, heart rate complexity, and splanchnic regional tissue oxygen saturation.

Conclusion:
Bedside monitoring of cardiovascular hemodynamics and oxygen delivery during packed red blood cell transfusion may inform individualized care for the premature infant with anemia and could be useful for the development of evidence-based practice guidelines.
Evidence for the Existence of a CXCL17 Receptor Distinct from GPR35
Authors: Binti Mohd Amir Nurul A. S. , Mackenzie Amanda E. , Jenkins Laura , Boustani Karim , Hillier Marston C. , Tsuchiya Tomoko , Milligan Graeme , Pease James E. 
Published: June 2018

Abstract
The chemokine CXCL17 is associated with the innate response in mucosal tissues but is poorly characterized. Similarly, the G protein–coupled receptor GPR35, expressed by monocytes and mast cells, has been implicated in the immune response, although its precise role is ill-defined. A recent manuscript reported that GPR35 was able to signal in response to CXCL17, which we set out to confirm in this study. GPR35 was readily expressed using transfection systems but failed to signal in response to CXCL17 in assays of β-arrestin recruitment, inositol phosphate production, calcium flux, and receptor endocytosis. Similarly, in chemotaxis assays, GPR35 did not confirm sensitivity to a range of CXCL17 concentrations above that observed in the parental cell line. We subsequently employed a real time chemotaxis assay (TAXIScan) to investigate the migratory responses of human monocytes and the monocytic cell line THP-1 to a gradient of CXCL17. Freshly isolated human monocytes displayed no obvious migration to CXCL17. Resting THP-1 cells showed a trend toward directional migration along a CXCL17 gradient, which was significantly enhanced by overnight incubation with PGE2. However, pretreatment of PGE2-treated THP-1 cells with the well-characterized GPR35 antagonist ML145 did not significantly impair their migratory responses to CXCL17 gradient. CXCL17 was susceptible to cleavage with chymase, although this had little effect its ability to recruit THP-1 cells. We therefore conclude that GPR35 is unlikely to be a bona fide receptor for CXCL17 and that THP-1 cells express an as yet unidentified receptor for CXCL17.
PD-1 Blockade Unleashes Effector Potential of Both High- and Low-Affinity Tumor-Infiltrating T Cells
Authors: Martínez-Usatorre Amaia , Donda Alena , Zehn Dietmar , Romero Pedro 
Published: June 2018

Abstract
Antitumor T cell responses involve CD8+ T cells with high affinity for mutated self-antigen and low affinity for nonmutated tumor-associated Ag. Because of the highly individual nature of nonsynonymous somatic mutations in tumors, however, immunotherapy relies often on an effective engagement of low-affinity T cells. In this study, we studied the role of T cell affinity during peripheral priming with single-peptide vaccines and during the effector phase in the tumor. To that end, we compared the antitumor responses after OVA257–264 (N4) peptide vaccination of CD8+ T cells carrying TCRs with high (OT-1) and low (OT-3) avidity for the N4 peptide in B16.N4 tumor-bearing C57BL/6 mice. Additionally, we assessed the response of OT-1 cells to either high-affinity (B16.N4) or low-affinity (B16.T4) Ag-expressing tumors after high-affinity (N4) or low-affinity (T4) peptide vaccination. We noticed that although low-affinity tumor-specific T cells expand less than high-affinity T cells, they express lower levels of inhibitory receptors and produce more cytokines. Interestingly, tumor-infiltrating CD8+ T cells show similar in vivo re-expansion capacity to their counterparts in secondary lymphoid organs when transferred to tumor-free hosts, suggesting that T cells in tumors may be rekindled upon relief of tumor immunosuppression. Moreover, our results show that αPD-1 treatment enhances tumor control of high- and low-affinity ligand-expressing tumors, suggesting that combination of high-affinity peripheral priming by altered peptide ligands and checkpoint blockade may enable tumor control upon low-affinity Ag recognition in the tumor.