bluuebunny/crossref_metadata_2025_split huggingface dataset:
Jewish-Christian Dialogues on Scripture in Late Antiquity
Authors: Bar-Asher Siegal Michal 
Published: May 2019

Stories portraying heretics ('minim') in rabbinic literature are a central site of rabbinic engagement with the 'other'. These stories typically involve a conflict over the interpretation of a biblical verse in which the rabbinic figure emerges victorious in the face of a challenge presented by the heretic. In this book, Michal Bar-Asher Siegal focuses on heretic narratives of the Babylonian Talmud that share a common literary structure, strong polemical language and the formula, 'Fool, look to the end of the verse'. She marshals previously untapped Christian materials to arrive at new interpretations of familiar texts and illuminate the complex relationship between Jews and Christians in Late Antiquity. Bar-Asher Siegal argues that these Talmudic literary creations must be seen as part of a boundary-creating discourse that clearly distinguishes the rabbinic position from that of contemporaneous Christians and adds to a growing understanding of the rabbinic authors' familiarity with Christian traditions.
High-throughput sequencing of fungal communities across the perennial ice block of Scărișoara Ice Cave
Authors: Mondini Antonio , Donhauser Jonathan , Itcus Corina , Marin Constantin , Perșoiu Aurel , Lavin Paris , Frey Beat , Purcarea Cristina 
Published: May 2019

ABSTRACTThis survey presents the first high-throughput characterisation of fungal distribution based on ITS2 Illumina sequencing of uncultured microbiome from a 1500 years old perennial ice deposit in Scărișoara Ice Cave, Romania. Of the total of 1 751 957 ITS2 sequences, 64% corresponded to 182 fungal operational taxonomic units, showing a low diversity, particularly in older ice strata, and a distinct temporal distribution pattern. Ascomycota was the major phylum in all ice samples, dominating the 400 and 1500 years old ice strata deposited during the cold Little Ice Age (LIA) and Dark Ages Cold Period, while Basidiomycota was mostly present in 900-years old ice formed during the Medieval Warm Period (MWP). Chytridiomycota and Mucoromycota phyla were present in recently formed and 400-years old ice, respectively. Among the 80 identified genera,Cryptococcus victoriae, commonly found in glacial habitats, was identified in all strata. A positive correlation between fungal distribution and ice conductivity, Ca, Na and Sr concentrations was observed across the ice block, with pH values trailing climate variations during LIA and MWP, respectively. Our record highlighted the presence of a complex climate and environmental-driven fungal community in perennial ice strata accumulated during the last 1500 years in Scărișoara Ice Cave.
Online Attention Bias Modification in Combination With Cognitive-Behavioural Therapy for Children and Adolescents With Anxiety Disorders: A Randomised Controlled Trial
Authors: de Lijster Jasmijn M. , Dieleman Gwendolyn C. , Utens Elisabeth M.W.J. , van der Ende Jan , Alexander Tamsin M. , Boon Albert , Hillegers Manon H.J. , Legerstee Jeroen S. 
Published: May 2019

AbstractAttention Bias Modification (ABM) targets attention bias (AB) towards threat, which is common in youth with anxiety disorders. Previous clinical trials showed inconsistent results regarding the efficacy of ABM, and few studies have examined the effect of online ABM and its augmented effect with cognitive behavioural therapy (CBT). The aim of the current study was to examine the efficacy of online ABM combined with CBT for children and adolescents with anxiety disorders in a randomised, double-blind, placebo-controlled trial. Children (aged 8–16 years) completed nine online sessions of ABM (n= 28) or online sessions of the Attention Control Condition (ACC;n= 27) over a period of 3 weeks (modified dot-probe task with anxiety disorder-congruent stimuli), followed by CBT. Primary outcomes were clinician-reported anxiety disorder status. Secondary outcomes were patient-reported anxiety and depression symptoms and AB. Results showed a continuous decrease across time in primary and secondary outcomes (ps < .001). However, no differences across time between the ABM and ACC group were found (ps > .50). Baseline AB and age did not moderate treatment effects. Online ABM combined with CBT does not show different efficacy compared with online ACC with CBT for children and adolescents with anxiety disorders.
Evidence for medieval salt-making by burning Eel-grass (Zostera marina L.) in the Netherlands
Authors: van Geel B. , Borger G.J. 
Published: May 2019

AbstractFrom the 8th/9th centuries onwards the former peat land area in the northwestern part of the Netherlands was drained and reclaimed. Drainage, peat digging and marine erosion of peat deposits created an extension of shallow marine habitats into which Zostera marina (Eel-grass) expanded. Modern publications do not note the use of Eel-grass as starting material for salt-making. Archaeological evidence, however, indicates salt-making activities by using Zostera in medieval times. We postulate that, after salt-containing peat had become difficult to obtain, Eel-grass was used for salt production.
Endoscopic assisted powered adenoidectomy versus conventional adenoidectomy – a randomised controlled trial
Authors: Juneja R , Meher R , Raj A , Rathore P , Wadhwa V , Arora N 
Published: May 2019

AbstractObjectiveTo compare endoscopic assisted powered adenoidectomy with conventional curettage adenoidectomy.MethodsA randomised controlled trial was conducted at a tertiary care teaching hospital. Fifty patients with a symptom complex pertaining to adenoid hypertrophy and requiring adenoidectomy were chosen and divided into 2 groups of 25 each. Patients in group A underwent conventional curettage adenoidectomy and those in group B underwent endoscopic assisted powered adenoidectomy. Comparison was based on the parameters of surgical time, intra-operative bleeding, post-operative pain and completeness of adenoid removal.ResultsThe surgical time was significantly longer with the powered instrument. Mean blood loss was greater in the powered group, but was statistically insignificant. The powered procedure fared significantly better, with lower pain scores and more instances of complete tissue resection.ConclusionA curved microdebrider blade can be used safely and precisely for adenoidectomy under endoscopic vision. It enables complete resection of adenoid tissue. This method also proves to be an excellent teaching aid.
Zinc-clotrimazole complexes are effective against Trichomonas vaginalis
Authors: Midlej Victor , Rubim Felipe , Villarreal Wilmer , Martins-Duarte Érica S. , Navarro Maribel , de Souza Wanderley , Benchimol Marlene 
Published: May 2019

AbstractTrichomonas vaginalis is a protozoan parasite that causes trichomoniasis in humans, the most prevalent non-viral sexually transmitted disease (STD). Imidazole compounds are used for the treatment of trichomoniasis, and metronidazole is the most commonly prescribed. However, these compounds can lead to parasite resistance and unwanted side effects. Therefore, there is a need for an alternative treatment for this disease. Here, we explored the potential of clotrimazole (CTZ) and zinc compounds, as well as CTZ complexed with zinc salts ([1] acetate [Zn(CTZ)2(Ac)2] and [2] a chloride [Zn(CTZ)2Cl2] complexes) against T. vaginalis. We synthesized the zinc complexed CTZ compounds and determined their concentration values that inhibited parasite growth by 50% (IC50). We used scanning and transmission electron microscopy to visualize the ultrastructural alterations induced by CTZ and their zinc complexes. The incubation of the parasites with [Zn(CTZ)2(Ac)2] complex inhibited their growth, yielding an IC50 of 4.9 µm. Moreover, there were changes in the shape of treated parasites, including the formation of surface projections that subsequently detached from the cell, in addition to changes in the hydrogenosomes, endoplasmic reticulum and Golgi complex. We found [Zn(CTZ)2(Ac)2] to be a highly effective compound against T. vaginalis in vitro, suggesting its potential utility as an alternative chemotherapy for trichomoniasis.
Two lineages of kingfisher feather lice exhibit differing degrees of cospeciation with their hosts
Authors: Catanach Therese A. , Johnson Kevin P. , Marks Ben D. , Moyle Robert G. , Valim Michel P. , Weckstein Jason D. 
Published: May 2019

AbstractUnlike most bird species, individual kingfisher species (Aves: Alcedinidae) are typically parasitized by only a single genus of louse (Alcedoffula,Alcedoecus, orEmersoniella). These louse genera are typically specific to a particular kingfisher subfamily. Specifically,AlcedoecusandEmersoniellaparasitize Halcyoninae, whereasAlcedoffulaparasitizes Alcedininae and Cerylinae. AlthoughEmersoniellais geographically restricted to the Indo-Pacific region,AlcedoecusandAlcedoffulaare geographically widespread. We used DNA sequences from two genes, the mitochondrial COI and nuclear EF-1αgenes, to infer phylogenies for the two geographically widespread genera of kingfisher lice,AlcedoffulaandAlcedoecus. These phylogenies included 47 kingfisher lice sampled from 11 of the 19 currently recognized genera of kingfishers. We compared louse phylogenies to host phylogenies to reconstruct their cophylogenetic history. Two distinct clades occur withinAlcedoffula, one that infests Alcedininae and a second that infests Cerylinae. All species ofAlcedoecuswere found only on host species of the subfamily Halcyoninae. Cophylogenetic analysis indicated thatAlcedoecus, as well as the clade ofAlcedoffulaoccurring on Alcedininae, do not show evidence of cospeciation. In contrast, the clade ofAlcedoffulaoccurring on Cerylinae showed strong evidence of cospeciation.
The “NICE Guideline” on the treatment of depression
Authors: Goldberg David 
Published: May 2019

AbstractThe National Institute of Clinical Excellence (NICE) in the UK is responsible for producing evidence based guidelines for the treatment of most common illnesses, both physical and psychological. NICE uses a hierarchy of evidence, ranging from data from meta-analyses of randomised controlled trials (RCT's) at the apex, to the opinions of acknowledged experts at the bottom. The task of preparing guideline for depression involved us in performing clean meta-analyses of around 8,000 published RCTs of the treatment of this disorder. Where drug treatments were concerned we used three indicators of efficacy, as well as considering toxicity, tolerability and cost. We also distinguished between studies carried out in primary care, and studies in patients treated by the mental health services. We found it helpful to arrange our report in terms of a “stepped care” model, addressing the indications for patients being referred on for more specialised, and expensive, treatments. In the full guideline we included our doubts that depression was a homogenous clinical entity, and our awareness of the limitations of relying on randomised controlled trials (RCT's) as the only source of evidence. This Editorial summarises the content of the guideline on the treatment of depression and discusses how it was received and also what it did not say.
Randomised controlled trial of a behavioural family intervention: 1 year and 11-years follow-up
Authors: Veltro Franco , Magliano Lorenza , Morosini Pierluigi , Fasulo Elvira , Pedicini Giuseppe , Cascavilla Isabella , Falloon Ian ,   Gruppo di Lavoro DSM-BN1
Published: May 2019

SUMMARYAim – To test the efficacy of a Behavioural Family Therapy (BFT) in a routine setting, both short and long term, of a community mental health service (CMHS). Methods – In a randomised clinical trial 24 patients with a diagnosis of schizophrenia, as confirmed by PSE-IX, were assigned to the BFT according to Falloon (n = 12) or to individual usual treatment (n = 12). They were assessed before and at the end of the active treatment (after one year), and after an 11-years follow-up with compared on basic indicators (hospitalisations, length of stay, drop-out rate) and standardised instruments of psychopathological symptoms, social functioning, family burden. Results – At one-year follow-up clinical important and statistically significant differences were observed for psychotic positive symptoms (p<0.01), self-care (p<0.01), autonomy in daily life (p<0.001), subjective/objective family burden (p<0.001). Other psychosocial variables showed positive outcomes non reaching statistical significance. At the 11-year follow-up, marked differences were observed only in hospitalisations and drop-outs. Conclusions – The BFT was rather easy to implement in a CMHS and very cost effective. However, as it has been shown in other studies, to keep all the benefits a consistent program of monitoring with booster sessions is essential.Declaration of Interest: in the last 2 years, none of the authors has had any interest or he/she has received any form of support, including that from drug companies and “honoraria” for lectures and consultancies, potentially in conflict with this scientific work.
Cognitive Performance, Aerobic Fitness, Motor Proficiency, and Brain Function Among Children Newly Diagnosed With Craniopharyngioma
Authors: Conklin Heather M. , Ness Kirsten K. , Ashford Jason M. , Scoggins Matthew A. , Ogg Robert J. , Han Yuanyuan , Li Yimei , Bradley Julie A. , Boop Frederick A. , Merchant Thomas E. 
Published: May 2019

AbstractObjectives:Craniopharyngioma survivors experience cognitive deficits that negatively impact quality of life. Aerobic fitness is associated with cognitive benefits in typically developing children and physical exercise promotes recovery following brain injury. Accordingly, we investigated cognitive and neural correlates of aerobic fitness in a sample of craniopharyngioma patients.Methods:Patients treated for craniopharyngioma [N=104, 10.0±4.6 years, 48% male] participated in fitness, cognitive and fMRI (n=51) assessments following surgery but before proton radiation therapy.Results:Patients demonstrated impaired aerobic fitness [peak oxygen uptake (PKVO2)=23.9±7.1, 41% impaired (i.e., 1.5SD&lt;normative mean)], motor proficiency [Bruininks-Oseretsky (BOT2)=38.6±9.0, 28% impaired], and executive functions (e.g., WISC-IV Working Memory Index (WMI)=96.0±15.3, 11% impaired). PKVO2correlated with better executive functions (e.g., WISC-IV WMIr=.27,p=.02) and academic performance (WJ-III Calculationr=.24,p=.04). BOT2 correlated with better attention (e.g., CPT-II omissionsr=.26,p=.04) and executive functions (e.g., WISC-IV WMIr=.32,p=.01). Areas of robust neural activation during an n-back task included superior parietal lobule, dorsolateral prefrontal cortex, and middle and superior frontal gyri (p&lt;.05, corrected). Higher network activation was associated with better working memory task performance and better BOT2 (p&lt;.001).Conclusions:Before adjuvant therapy, children with craniopharyngioma demonstrate significantly reduced aerobic fitness, motor proficiency, and working memory. Better aerobic fitness and motor proficiency are associated with better attention and executive functions, as well as greater activation of a well-established working memory network. These findings may help explain differential risk/resiliency with respect to acute cognitive changes that may portend cognitive late effects. (JINS, 2019,25, 413–425)
Effect of Cognitive Reserve on Children With Traumatic Brain Injury
Authors: Donders Jacobus , Kim Eunice 
Published: May 2019

AbstractObjectives:Traumatic brain injury can result in cognitive impairments in children. The objective of this retrospective study was to determine to what extent such outcomes are moderated by cognitive reserve, as indexed by parental education.Methods: Sixty 6- to 16-year-old children completed the Wechsler Intelligence Scale for Children—Fifth Edition (WISC–V) within 30–360 days after having sustained a traumatic brain injury (TBI). Their Full-Scale IQ and factor index scores were compared to those of demographically matched controls. In addition, regression analysis was used to investigate in the TBI group the influence of injury severity in addition to parental education on WISC–V factor index scores.Results: Cognitive reserve moderated the effect of TBI on WISC–V Full Scale IQ, Verbal Comprehension, and Visual Spatial. In the TBI group, it also had a protective effect with regard to performance on the Verbal Comprehension, Visual Spatial, and Fluid Reasoning indices. At the same time, greater injury severity was predictive of lower Visual Spatial and Processing Speed index scores in the TBI group.Conclusions: Cognitive reserve as reflected in parental education has a moderating effect with regard to children’s performance on the WISC–V after TBI, such that higher cognitive reserve is associated with greater preservation of acquired word knowledge and understanding of visual relationships. Measures that emphasize speed of processing remain affected by severity of TBI, even after accounting for the protective effect associated with cognitive reserve. (JINS, 2019,25, 355–361)
Revisiting Temporal Evolution of Cu-Rich Precipitates in Fe–Cu Alloy: Correlative Small Angle Neutron Scattering and Atom-Probe Tomography Studies
Authors: Ahlawat Sarita , Sarkar Sudip Kumar , Sen Debasis , Biswas Aniruddha 
Published: May 2019

AbstractBinary Fe–Cu alloys are effective prototypes for investigating radiation-induced formation and growth of nanometric Cu-rich precipitates (CRPs) in nuclear reactor pressure vessels. In this report, the temporal evolution of CRPs during thermal aging of Fe–Cu binary alloys has been investigated by using complementary techniques such as atom probe tomography (APT) and small-angle neutron scattering (SANS). We report a detailed quantitative evolution of a rarely observed morphological transformation of Cu precipitates from spherical to ellipsoid with a significant change (approximately two times) in aspect ratio, an effect known to be associated with the 9R-3R structural transition of the precipitates. It is demonstrated through APT that the precipitates remain spherical up to 8 h, however, they subsequently convert to oblate ellipsoid upon further aging. SANS analysis also detected signs of this morphological transition in reciprocal space. Furthermore, SANS quantifies evolution of the precipitates and corroborates well with the APT results. Interestingly, the power-law exponent of the temporal evolution for mean size and number density agree reasonably well with the Lifshitz–Slyozov–Wagner model, in spite of the complex morphological evolution of the precipitates.
Franz Liszt's Heir: Ferruccio Busoni and Weimar
Authors: Knyt Erinn E. 
Published: May 2019

When Franz Liszt died, the world lost an innovative composer, mentor, and pianist. Although his influence did not die with him, few of his successors can claim to have walked in his footsteps – to have lived and taught in the same rooms – and to have shared many of his ideals. Ferruccio Busoni did just that when the Grand Duke Carl Alexander invited him to hold piano master classes in Weimar in 1900 and 1901, just as he had invited Liszt to do nearly two decades earlier (1881–1885).This article shows how Liszt's activities in Weimar as Pedagogue and as Kapellmeister (1848–1861) became models for Busoni as he sought to position himself as a prominent ‘musical polymath’ at the turn of the century. Yet Busoni not only emulated Liszt, he also promoted him in an age when the older composer was considered of only tangential importance.By producing authoritative editions of Liszt's music, and perhaps more significantly, by emulating Liszt's activities as a transcriber and composer, Busoni enhanced piano sonority while extending Liszt's ideas about the future of music. In that way, he shared attitudes associated with the Zukunftsmusik movement, and his outlook was rooted in Liszt's compositions, as opposed to Richard Wagner's. At the same time, he helped foster a lineage of young musicians who patterned their careers and music after Liszt.Drawing on surviving memoirs, letters, scores, essays and concert programmes, this article thus explores Liszt's impact on Busoni and his mentees. It reveals a musician not only emulating Liszt, but also expanding upon his ideas and promoting them to others.
Getting involved: the extent and impact of patient and public involvement in the Swedish health system
Authors: Fredriksson Mio , Tritter Jonathan 
Published: May 2019

AbstractPatient and public involvement (PPI) is framed as beneficial for individuals and for the health system. However, little is known about the extent of involvement, or of its impact. Based on data from Sweden, we show that apart from voting in regional elections (76%), more people reported involvement as individual patients (23%) than part of collective activities (5%) or activities relating to a citizen perspective (4%). There was no correlation between how many people participated and the estimated impact – which was generally low. More extensive involvement is thus not linked to the potential to influence decisions. We argue that to achieve the benefits associated with PPI it is crucial to understand more about people's motivation for being involved and what underlies low estimates of impact. This requires a more systematic approach to involvement, how it is evaluated and its results communicated to participants and the society. We also argue that a future challenge for the Swedish health system, and for other similar health systems, is to support long-term collective involvement in the midst of growing individualization of health services and involvement opportunities primarily intended for patients.
Design of WLAN/WiMAX band notch super-wideband microstrip fractal antennas
Authors: Abdpour S. S. , Azadi-Tinat N. , Oraizi H. , Ghalibafan J. 
Published: May 2019

AbstractA super-wideband microstrip fractal antenna is designed with miniaturized dimensions of 21 mm × 23.5 mm × 1 mm and generation of dual rejection bands for WLAN/WiMAX systems has been achieved. The triangular fractal shape slots are placed inside a circular patch and the antenna is miniaturized by using a repetition frequency resonance technique. The proposed antenna frequency range 2.6–40 GHz operates for VSWR of less than 2. Two band rejections for the frequency ranges 5.1–5.8 GHz and 3.4–3.7 GHz are created by one enhanced slot at the feed line and one split-ring resonator at the back of antenna. HFSS 3D software was used for computer simulation. The proposed antenna is fabricated on the FR4 substrate with 1 mm thickness. The measurement data show good agreement with the simulation results.
Still a blind spot: The protection of LGBT persons during armed conflict and other situations of violence
Authors: Margalit Alon 
Published: May 2019

AbstractThis article draws attention to the situation of LGBT persons during armed conflict. Subjected to violence and discrimination outside the context of armed conflict, the latter aggravates their vulnerability and exposure to various abuses. Despite important progress made with respect to their protection under human rights law, a similar effort is largely absent from the international humanitarian law discourse. This article accordingly highlights some of the norms and challenges pertaining to the protection of LGBT persons in time of war.