bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maximizing Value of Information of a Horizontal Polymer Pilot Under Uncertainty
Authors: Steineder Dominik , Clemens Torsten , Osivandi Keyvan , Thiele Marco 
Published: April 2018

Abstract
Polymer injection might lead to incremental oil recovery and increase the value of an asset. Several steps have to be taken to mature a polymer injection project. The field needs to be screened for applicability of polymer injection, laboratory experiments have to be performed, and a pilot project might be required prior to field implementation.
The decision to perform a pilot project can be based on a Value of Information (VoI) calculation. The VoI can be derived by performing a workflow capturing the impact of the range of geological scenarios as well as dynamic and polymer parameters on incremental Net Present Value (NPV). The result of the workflow is a Cumulative Distribution Function (CDF) of NPV linked to prior distributions of model parameters and potential observables from the polymer injection pilot.
The impact of various parameters on the CDF of the field-wide NPV can be analyzed and in turn used to decide on what measurements from the pilot have a strong sensitivity on the NPV CDF and are thus informative. In the case shown here, the water cut reduction in the pilot area has a strong impact on the NPV CDF of the polymer injection field implementation. To extract maximum information, the response of the pilot for water cut reduction needs to be optimized under uncertainty.
To calculate the VoI, the Expected Monetary Value (EMV) difference of a decision tree with and without the pilot can be used if the Decision Maker (DM) is risk neutral. However, if the DM requires hurdle values through a Probability of Economic Success (PES), Value Functions (VF) and Decision Weights according to the Prospect Theory should be used. Applying risk hurdles requires a consistent use of VFs and Decision Weights for calculating VoI and the Probability of Maturation (POM) of projects.
Calculation of Relative Permeability Using Well Test Data in Gas-Condensate Reservoirs
Authors: Al Abdulwahab Ibrahim , Jamiolahmady Mahmoud , Whittle Tim 
Published: April 2018

Abstract
Analysing well test data from gas-condensate reservoirs can be challenging, particularly when pressure drops below the dew point and condensate forms near the well. Usually, a single-phase pseudo-pressure approach is used to analyse the corresponding pressure transient well test data in combination with a composite reservoir model, but this approach has its shortcomings. A two-phase pseudo-pressure approach has been shown to give better results, but it requires relative permeability (kr) data which are not readily available.
The paper demonstrates the reliability of calculating a pressure versus radius profile from pressure versus time build up data from tests on wells in gas-condensate reservoirs. The calculation is based on the probe radius concept originally proposed for single-phase systems. It also evaluates the possibility of obtaining, analytically, kr data affected by pressure and velocity in single-rate and multi-rate tests. The calculation is based on Darcy's law using the pressure derivative with respect to distance obtained from the pressure versus radius profile. The theory of these calculations is verified by comparing the results with the output from a numerical simulator based on a single-layer single-well radial reservoir model. A simple binary rich gas condensate fluid was used in the numerical simulation.
The results demonstrate that the pressure versus radius profile using probe radius theory reasonably matches the corresponding pressure versus radius profile output from the numerical simulation. This also shows that the method can reliably predict the condensate bank radius. At first, the analytical approach used to calculate kr, as a function of radius, resulted in oscillations due to the nature of derivative calculation involved. The source of the kr noise was treated following two separate approaches that can be used depending on the level of noise versus ease of use. The calculated kr versus radius data showed good agreement with the corresponding grid block kr versus radius data predicted by the simulator for various rock types and flow rates.
The method described in this paper provides a practical tool to estimate kr data that can be used to calculate two-phase pseudo pressure and hence potentially improve the analysis of gas-condensate test data affected by condensate banking and velocity. The derived kr data may also have other applications.
Development and Certification of Formononetin Reference Material for Quality Control of Functional Foods and Botanical Supplements
Authors: Gong Ningbo , Zhang Baoxi , Hu Kun , Gao Zhaolin , Du Guanhua , Lu Yang 
Published: April 2018

Background:
Formononetin is a common soy isoflavonoid that can be found abundantly in
many natural plants. Previous studies have shown that formononetin possesses a variety of activities
which can be applied for various medicinal purposes. Certified Reference Materials (CRMs) play a
fundamental role in the food, traditional medicine and dietary supplement fields, and can be used for
method validation, uncertainty estimation, as well as quality control.

Methods:
The purity of formononetin was determined by Differential Scanning Calorimetry (DSC),
Coulometric Titration (CT) and Mass Balance (MB) methods.

Results:
This paper reports the sample preparation methodology, homogeneity and stability studies,
value assignment, and uncertainty estimation of a new certified reference material of formononetin.
DSC, CT and MB methods proved to be sufficiently reliable and accurate for the certification purpose.
The purity of the formononetin CRM was therefore found to be 99.40% ± 0.24 % (k = 2) based on the
combined value assignments and the expanded uncertainty.

Conclusion:
This CRM will be a reliable standard for the validation of the analytical methods and for
quality assurance/quality control of formononetin and formononetin-related traditional herbs, food
products, dietary supplements and pharmaceutical formulations.
5th International Postgraduate Conference on Pharmaceutical Sciences 2017 (iPoPS 2017)
Authors: Uitm Selangor May Faculty Of Pharmacy 
Published: April 2018

WELCOME MESSAGE FROM THE VICE CHANCELLOR OF UNIVERSITI TEKNOLOGI MARA (UiTM)Assalamualaikum wbt I would like to congratulate the Postgraduate Society of Faculty of Pharmacy, UiTM Puncak Alam for organising the 5th International Postgraduate Conference on Pharmaceutical Sciences 2017 (iPoPS 2017).This conference has been successfully organised since 2012 by the postgraduate students together with the Faculty of Pharmaceutical Sciences, Tokyo University of Science, Japan without fail. This symbolises the strong collaboration between UiTM and TUS towards academic excellence, which enhances our academic visibility. UiTM has been ranked top 200 in the QS World University Ranking by subject 2017 for Pharmacy & Pharmacology. This is a big achievement for a young faculty of 14 years.On that note, contributions from the postgraduates play an important role in the development of human capital headed for a personified nation with humanistic values, forward thinking with an edge in entrepreneurship. Postgraduate students nowadays not only face challenges in completing their studies but also competing with the fast pace of ever changing technology. Therefore, we need to allow their full integration into the global knowledge society together with international collaboration to advance the quality of higher education worldwide.Participation in event with different cultures and background like iPoPS 2017 helps develop articulate thinking and inspire healthy competition of ideas among the young, budding research generation in Malaysia. Hopefully, by continuing to invite eminent speakers from all over the world, the Conference will gain its recognition in the international research community and make UiTM soar upwards. We trust this Conference will be a success and carry on for years to come. Congratulations!EMERITUS PROFESSOR DATO’ DR. HASSAN SAIDVice-Chancellor Universiti Teknologi MARA (UiTM)
Prevalencia de prescripción inapropiada de terapia supresora de ácido en adultos hospitalizados en un hospital general en Bogotá
Authors: Posada Bustos Sebastian , De León Fernández Nathalia , González Morales Rossmary , Tihanyi Feldman Jonathan , Vera Chamorro José Fernando 
Published: April 2018

Objetivo: Determinar la prevalencia de prescripción de terapia supresora de ácido (TSA) conformada por los inhibidores de la bomba de protones (IBP) y los antagonistas de los receptores H2 (AR-H2) en pacientes adultos hospitalizados en el Hospital Universitario Fundación Santa Fe de Bogotá (HU-FSFB) que no corresponda a las indicaciones de las guías de práctica clínica (GPC).Métodos: Estudio observacional descriptivo de corte transversal que incluyó pacientes adultos hospitalizados en el HU-FSFB con prescripción de TSA de novo, determinando las indicaciones de TSA y comparándolas con las indicaciones validadas. Se excluyeron: pacientes con prescripción o consumo previo de TSA durante dos semanas, y pacientes internados en unidad de cuidados intensivos o con hospitalización menor a un día.Resultados: Entre enero y julio de 2015, se incluyeron 306 pacientes con un promedio de edad de 56,6 ( años, con una prevalencia de prescripción de TSA sin indicación basada en la evidencia del 59,5%. Las indicaciones no basadas en la evidencia más comunes fueron: profilaxis sangrado por ulcera gastrointestinal en pacientes de bajo riesgo: 64,9% y causa no establecida en un 13,7%. Se encontró asociación estadísticamente significativa entre tiempo de hospitalización menor a siete días (OR: 2,39 IC 95% 1,4-3,9) y edad menor a 60 años (OR: 1,9 IC 95% 1,2-3,03) con prescripción inapropiada de TSA.Conclusión: Existe una alta prevalencia (59,5%) de prescripción inapropiada de TSA en pacientes adultos hospitalizados con asociación positiva en menores de 60 años y corta hospitalización en el HU-FSFB.
SEASONAL AND INTERANNUAL PATTERN OF METEOROLOGICAL VARIABLES IN CUIABÁ, MATO GROSSO STATE, BRAZIL
Authors: Machado Nadja Gomes , Biudes Marcelo Sacardi , Querino Carlos Alexandre Santos , Danelichen Victor Hugo De Morais , Velasque Maísa Caldas Souza 
Published: April 2018

ABSTRACT. Cuiab´a is located on the border of the Pantanal and Cerrado, in Mato Grosso State, which is recognized as one of the biggest agricultural producers of Brazil. The use of natural resources in a sustainable manner requires knowledge of the regional meteorological variables. Thus, the objective of this study was to characterize the seasonal and interannual pattern of meteorological variables in Cuiab´a. The meteorological data from 1961 to 2011 were provided by the Instituto Nacional de Meteorologia (INMET – National Institute of Meteorology). The results have shown interannual and seasonal variations of precipitation, solar radiation, air temperature and relative humidity, and wind speed and direction, establishing two main distinct seasons (rainy and dry). On average, 89% of the rainfall occurred in the wet season. The annual average values of daily global radiation, mean, minimum and maximum temperature and relative humidity were 15.6 MJ m–2 y–1, 27.9◦C, 23.0◦C, 30.0◦C and 71.6%, respectively. Themaximum temperature and the wind speed had no seasonal pattern. The wind speed average decreased in the NWdirectionand increased in the S direction.Keywords: meteorological variables, climatology, ENSO. RESUMO. Cuiabá está localizado na fronteira do Pantanal com o Cerrado, no Mato Grosso, que é reconhecido como um dos maiores produtores agrícolas do Brasil. A utilização dos recursos naturais de forma sustentável requer o conhecimento das variáveis meteorológicas em escala regional. Assim, o objetivo deste estudo foi caracterizar o padrão sazonal e interanual das variáveis meteorológicas em Cuiabá. Os dados meteorológicos de 1961 a 2011 foram fornecidos pelo Instituto Nacional de Meteorologia (INMET). Os resultados mostraram variações interanuais e sazonais de precipitação, radiação solar, temperatura e umidade relativa do ar e velocidade e direção do vento, estabelecendo duas principais estações distintas (chuvosa e seca). Em média, 89% da precipitação ocorreu na estação chuvosa. Os valores médios anuais de radiação diária global, temperatura do ar média, mínima e máxima e umidade relativa do ar foram 15,6 MJ m–2 y–1, 27,9◦C, 23,0◦C, 30,0◦C e 71,6%, respectivamente. A temperatura máxima e a velocidade do vento não tiveram padrão sazonal. A velocidade média do vento diminuiu na direção NW e aumentou na direção S.Palavras-chave: variáveis meteorológicas, climatologia, ENOS.
Solving the “Mystery” of Profiling Fraud: Teaching Students About Occupational Fraud by Examining Episodes of Mystery Diners
Authors: Daigle Ronald J. , Hayes David C. , McSwain Dwayne N. 
Published: April 2018

ABSTRACT
Students learn about the many different aspects of occupational fraud by reading the Association of Certified Fraud Examiners (ACFE) Report to the Nations on Occupational Fraud and Abuse (Report) and applying what they learn to one of two episodes of the television show Mystery Diners, which features an undercover fraud investigation in a restaurant setting. Applying the ACFE Report to a setting generally familiar to students helps them gain insight into occupational fraud. Pre-/post-test and survey results reveal that students significantly increased their knowledge of how occupational fraud is committed and detected, traits of victim organizations, characteristics of perpetrators, and case results (what actions are or are not taken against perpetrators) across two different episodes and two editions of the ACFE Report. Feedback shows students found the case valuable and enjoyable and would find more cases like this beneficial. Instructors can modify the case for other episodes (more than 100 are available) and further editions of the ACFE Report to help students learn about occupational fraud.
Higher Collagen VI Formation Is Associated With All-Cause Mortality in Patients With Type 2 Diabetes and Microalbuminuria
Authors: Rasmussen Daniel G.K. , Hansen Tine W. , von Scholten Bernt J. , Nielsen Signe H. , Reinhard Henrik , Parving Hans-Henrik , Tepel Martin , Karsdal Morten A. , Jacobsen Peter K. , Genovese Federica , Rossing Peter 
Published: April 2018

OBJECTIVEType 2 diabetes is a common risk factor for the development of chronic kidney disease (CKD). Enhanced de novo collagen type VI (COL VI) formation has been associated with renal fibrosis and CKD. We investigated the hypothesis that PRO-C6, a product specifically generated during COL VI formation, is prognostic for adverse outcomes in patients with type 2 diabetes and microalbuminuria.RESEARCH DESIGN AND METHODSIn a prospective, observational study, we measured PRO-C6 in the serum (S-PRO-C6) and urine (U-PRO-C6) of 198 patients with type 2 diabetes and microalbuminuria without symptoms of coronary artery disease. Patients were followed for a median of 6.5 years, and end points were a composite of cardiovascular events (n = 38), all-cause mortality (n = 26), and reduction of estimated glomerular filtration rate (eGFR) of &gt;30% (disease progression [n = 42]). Cox models were unadjusted and adjusted for the conventional risk factors of sex, age, BMI, systolic blood pressure, LDL cholesterol, smoking, HbA1c, plasma creatinine, and urinary albumin excretion rate.RESULTSDoubling of S-PRO-C6 increased hazards for cardiovascular events (hazard ratio 3.06 [95% CI 1.31–7.14]), all-cause mortality (6.91 [2.96–16.11]), and disease progression (4.81 [1.92–12.01]). Addition of S-PRO-C6 to a model containing conventional risk factors improved relative integrated discrimination by 22.5% for cardiovascular events (P = 0.02), 76.8% for all-cause mortality (P = 0.002), and 53.3% for disease progression (P = 0.004). U-PRO-C6 was not significantly associated with any of the outcomes.CONCLUSIONSS-PRO-C6 generated during COL VI formation predicts cardiovascular events, all-cause mortality, and disease progression in patients with type 2 diabetes and microalbuminuria.
PENGARUH PENGGUNAAN METODE PEMBELAJARAN TUTOR SEBAYA BERBANTUAN MEDIA LEAFLET TERHADAP HASIL BELAJAR TIK SISWA KELAS VIII SMP NEGERI 16 PADANG
Authors: Hidayati Abna 
Published: April 2018

Penelitian ini didasari hasil belajar TIK pada SMP 16 Padang yang belum optimal. Penelitian ini bertujuan melihat Pengaruh Penerapan Metode Tutor sebaya Berbantuan Media Leaflet terhadap Hasil Belajar TIK Siswa Kelas VIII SMP Negeri 16 Kota Padang.
Penelitian ini menggunakan pendekatan kuantitatif berbentuk quasy experiment. Populasi penelitian ini adalah siswa kelas VIII SMP Negeri 16 Kota Padang Tahun Pelajaran 2016/2017. Sampel diambil dengan teknik purposive sampling, sehingga yang menjadi sampel adalah siswa kelas VIII.4 (kelas eksperimen) dan siswa kelas VIII.7 (kelas kontrol). Data yang diambil dari penelitian ini adalah data primer tentang hasil belajar TIK. Instrumen penelitian yang digunakan adalah tes hasil belajar berupa soal objektif sebanyak 40 butir soal.Setelah diperoleh data hasil belajar, dilakukan uji normalitas dan uji homogenitas, kemudian dilanjutkan dengan uji t.
Hasil penelitian menunjukkan nilai rata-rata siswa yang menggunakan metode tutor sebaya berbantuan media leafletyaitu 81,92 lebihtinggidari yang menerapkan pembelajaran konvensionalyaitu73,57. Sedangkandariperhitungan t-tesdiperoleh thitung >ttabel, yaitu 5,56 > 1,66 padataraf signifikan α 0,05.Dengan demikian penerapan metode tutor sebaya berbantuan media leaflet berpengaruh secara signifikan terhadap hasil belajar TIK siswa kelas VIII di SMP Negeri 16 Kota Padang.
A ideia de seminário e o desejo de aprender: das primeiras iniciativas em Halle (1695) à intensidade experimental de Vincennes (1968)
Authors: Paz Ana , Do Ó Jorge 
Published: April 2018

No processo de sua emergência histórica, a sequência das ideias e práticas de trabalho que ligaram a missão da universidade à investigação, e já não exclusivamente ao ensino, é apresentada. O conceito de seminário, originado em Halle no século 17, viria a identificar a Universidade de Berlim, em 1810, sendo depois irradiado a partir desse centro. A institucionalização do seminário esteve de facto1 na origem do desenvolvimento de formas de relação pedagógica experimentais e de processos de escrita inovadores nos domínios das humanidades e das ciências sociais, totalmente direcionados para as zonas de fronteira e para o amanhã da ciência. Uma genealogia desse gesto é traçada, detendo-se particularmente sobre o idealismo alemão do século 18 em torno da universidade alemã, e conclui com a experiência de Vincennes Paris-VIII, ligada aos autores do chamado pós-estruturalismo francês. Uma longa formação discursiva reativou a hipótese da criação e da invenção no interior do espaço universitário.
Fatores associados ao desempenho acadêmico de estudantes de Nutrição no Enade
Authors: Rocha Aline Lemes da Paixão , Leles Claudio Rodrigues , Queiroz Maria Goretti 
Published: April 2018

O desempenho estudantil é de natureza multifatorial. São inexistentes os estudos acerca dos aspectos que interferem no desempenho de estudantes de Nutrição em exames como o Exame Nacional de Desempenho de Estudantes (Enade). Este artigo tem o objetivo de verificar a associação entre o desempenho de estudantes concluintes de Nutrição no Enade e fatores socioeconômicos, trajetória acadêmica e perfil da instituição, mediante a utilização de dados secundários produzidos pelo Instituto Nacional de Estudos e Pesquisas Educacionais Anísio Teixeira (Inep). Realizou-se análise descritiva das variáveis e, para determinação dos fatores associados ao desempenho acadêmico, aplicaram-se regressão linear simples e regressão múltipla (p<0,05). A variabilidade do desempenho acadêmico pôde ser explicada em 11,7% pelas variáveis testadas no modelo de regressão. Constatou-se menor desempenho entre estudantes negros, que trabalham eventualmente, com renda familiar de até três salários mínimos, de pais e mães com nenhuma escolaridade, que cursaram metade do ensino médio em escola pública e metade em escola privada, que receberam bolsa de estudos ou financiamento e não ingressaram no ensino superior por políticas afirmativas. A categoria administrativa da instituição de educação superior (IES) foi o principal fator associado ao desempenho no Enade. Discentes que ingressaram via políticas afirmativas apresentaram desempenho maior que aqueles que não ingressaram por essas políticas. Observou-se que melhores condições do ensino fundamental e médio são importantes para que todos os estudantes concorram em situação de igualdade ao ensino superior.
Development and psychometric testing of the Canine Owner-Reported Quality of Life questionnaire, an instrument designed to measure quality of life in dogs with cancer
Authors: Giuffrida Michelle A. , Brown Dorothy Cimino , Ellenberg Susan S. , Farrar John T. 
Published: April 2018

Abstract
OBJECTIVE To describe development and initial psychometric testing of an owner-reported questionnaire designed to standardize measurement of general quality of life (QOL) in dogs with cancer.
DESIGN Key-informant interviews, questionnaire development, and field trial.
SAMPLE Owners of 25 dogs with cancer for item development and pretesting and owners of 90 dogs with cancer for reliability and validity testing.
PROCEDURES Standard methods for development and testing of questionnaire instruments intended to measure subjective states were used. Items were generated, selected, scaled, and pretested for content, meaning, and readability. Response items were evaluated with exploratory factor analysis and by assessing internal consistency (Cronbach α) and convergence with global QOL as determined with a visual analog scale. Preliminary tests of stability and responsiveness were performed.
RESULTS The final questionnaire—which was named the Canine Owner-Reported Quality of Life (CORQ) questionnaire—contained 17 items related to observable behaviors commonly used by owners to evaluate QOL in their dogs. Several items pertaining to physical symptoms performed poorly and were omitted. The 17 items were assigned to 4 factors—vitality, companionship, pain, and mobility—on the basis of the items they contained. The CORQ questionnaire and its factors had high internal consistency (Cronbach α = 0.68 to 0.90) and moderate to strong correlations (r = 0.49 to 0.71) with global QOL as measured on a visual analog scale. Preliminary testing indicated good test-retest reliability and responsiveness to improvements in overall QOL.
CONCLUSIONS AND CLINICAL RELEVANCE The CORQ questionnaire was a valid, reliable owner-reported questionnaire that measured general QOL in dogs with cancer and showed promise as a clinical trial outcome measure for quantifying changes in individual dog QOL occurring in response to cancer treatment and progression.