bluuebunny/crossref_metadata_2025_split huggingface dataset:
SCREENING OF THE ANTIOXIDANT ACTIVITY OF CRUDE EXTRACTS IN 86 ALGAE SPECIES FROM EL JADIDA COAST (MOROCCO)
Authors: Chibi Fatima , Rchid Halima , Arsalane Wafa , Nmila Rachid 
Published: March 2019

Objective: This work aimed to screen the antioxidant activity of marine macroalgae from the Moroccan Atlantic coast (region of El Jadida).
Methods: Evaluation of the antioxidant activity of different collected species, lyophilized and extracted with a solvent mixture chloroform/methanol (2/1; v/v) was conducted according to two techniques, first by thin layer chromatography (tlc) then by spectrophotometry, using a free radical 2,2-diphenyl-1-picrylhydrazyl (dpph). The sampling on a distance of 110 km allowed to harvest 86 algal species (16 brown algae, 47 red algae, 14 green algae and 9 algae being identified).
Results: The analysis by thin layer chromatography reveals an antioxidant activity in nearly half of harvested algal species (52.32 %). This activity varies depending on the concentration of the extract and in function of incubation time in the presence of dpph. The monitoring of the kinetics of degradation of dpph by spectrophotometer in the presence of extracts which were active by tlc allowed to confirm the results and select the most active algal species based on the percentage of remaining dpph in the medium after 120 min of reaction: Fucus spiralis (17.02 %), Cyctoseira ericoides (12.16 %) (Phaeophyceae), and Gracilaria multipartita (36%), Halopitys incurvus (5%) (Rhodophyceae).
Conclusion: The results show that the methodology adopted in this work is reliable and can be used for rapid screening of antioxidant property in plants and the species: Fucus spiralis, Cyctoseira ericoides, Gracilaria multipartita, and Halopitys incurvus can be a promising source of natural compounds endowed with high antioxidant potential.
IN SILICO AND IN VITRO ASSAY OF HGV ANALOGUE AS ANTIBACTERIAL
Authors: Wijianto Bambang , . RITMALENI , PURNOMO HARI , NURROCHMAD ARIEF 
Published: March 2019

Objective: The objective of this research was to design a new analogue compound, hexagamavunon (HGV).
Methods: New design of analogue compound, HGV, was performed by QSAR study using BuildQSAR program. In this QSAR study, parameterized model (PM3) method using the Polak-Ribière algorithm was applied to calculate the optimal geometric structures of the used compounds. The new analogue compound, HGV had been synthesized using aldol condensation reaction. The assay of antibacterial activities was performed using the dilution method. Molecular operating environment (MOE) program was used for protocol docking.
Results: The results of QSAR study reveal the good relationship of antibacterial activities. The in vitro antibacterial activities of 2,6-bis((E)-3,5-dibromo-4-hydroxybenzylidene) cyclohexan-1-one (A113) indicates the good potential to against S. aureus, B. subtilis and E. coli with IC50 27.3 μg/ml, 30.9 μg/ml, 32 μg/ml respectively. This is in accordance with the in silico evaluation showing that 2,6-bis((E)-3,5-dibromo-4-hydroxybenzylidene) cyclohexan-1-one has lower docking score than both amoxicillin and cefoxitin do as the native ligand of receptor 3MZE.
Conclusion: Based on in silico and in vitro assay, 2,6-bis((E)-3,5-dibromo-4-hydroxybenzylidene) cyclohexan-1-one (A113) has good antibacterial activities against S. aureus, B. subtilis, and E. coli.
FREE-RADICAL SCAVENGING ACTIVITY LEAF EXTRACT OF LITSEA LAEVIGATA GAMBLE
Authors: SUJATHA S. , SEKAR T. 
Published: March 2019

Objective: In the present study, antioxidant activity in the leaf of the pet-ether, chloroform, acetone and methanolic extracts from Litsea laevigata Gamble. Leaf was investigated by employing established in vitro studies. L. laevigata belongs to the Lauraceae family.
Methods: The capability of the plant extract to act as hydrogen/electrons donor or scavenger of radicals were determined by in vitro antioxidant assays using 2,2-diphenyl-2-picrylhydrazyl free radical (DPPH.) scavenging, reducing power assay, superoxide radical (O2*-) scavenging activity, phosphomolybdenum assay, FRAP, ABT and metal chelating activity were performed to know the antioxidant potency of the plant extract of leaves of L. laevigata.
Results: Results are evaluated higher in leaf extract of L. laevigata recorded total phenol, total flavonoid, and tannin. The present state of work was designed to evaluate the phytochemical, antioxidant in the plant leaf extracts of L. laevigata. The plant L. laevigata methanolic extract of leaf showed greater IC50 antioxidant activity of DPPH assay (5.264 µg/ml) and compare to other extract, higher phosphomolybdenum reduction (164.36 mg/g), better Reducing power activity leaf in methanol (0.711%), higher ferric reducing power (4060.66MmolFe(II)E/mg), and higher in superoxide radical scavenging activity in (78.12 mg/ml). However, the better metal chelating ability was shown by the water extracts of the leaf (5.145 EDTAE/100g) compared to other solvent extracts.
Conclusion: The result indicates the total phenol and antioxidant activity potential of L. laevigata.
POPULATION STRUCTURE OF KAEMPFERIA GALANGA L. FROM EASTERN INDIA
Authors: PARIDA REENA , MOHANTY SUJATA , NAYAK SANGHAMITRA 
Published: March 2019

Objective: India has been a producer of a large number of aromatic medicinal plants which serves as a valuable genetic resource for future quality improvement to meet the ever-growing demand of human essential products. Thus, an urgent need arises for germplasm conservation of these high yielding varieties to help the pharmaceutical and other industries. For this understanding, the population structure is essential in order to explore their genetic identification by fingerprinting and molecular characterization.
Methods: In the present study DNA was isolated using modified Cetyl Trimethyl Ammonium Bromide (CTAB) method and Polymerase Chain Reaction (PCR) was performed according to standardized method along with its data analysis. This study was undertaken to characterize the highly medicinal Kaempferia galanga collected from 4 different populations of Odisha using the molecular markers as Random Amplified Polymorphic DNA and Inter-Simple Sequence Repeats for the first time.
Results: A dendrogram constructed through Sequential Agglomerative Hierarchical and Nested (SAHN) clustering and Unweighted Pair Group Method with Arithmetic mean (UPGMA) analysis showed an average similarity of 0.993 ranging between 0.967 to 1.000. Jaccard’s similarity coefficient of combined markers segregated the genotypes into two main clusters, 1 with six samples and the others at 0.98 similarity coefficient.
Conclusion: Hence, the molecular analysis could be further used for the identification of important novel gene present in Kaempferia galanga which can be utilized for future crop improvement as well as pharmacological activities.
Vitex Species: Review on Phytochemistry and Pouch Design for Nutritional Benefits
Authors: Abdul Hakeem Nur Rejai Salmah , Md Yusof Nuruljannah , Jahidin Aisyah Hasyila , Hazizul Hasan Mizaton , Mohsin Hannis Fadzillah , Abdul Wahab Ibtisam 
Published: March 2019

Vitex trifolia or locally known as lemuni, is well documented for its medicinal properties including anticancer, antibacterial and wound healing. For years, the leaves and flowers were consumed for anti-aging and general well-being. It is also commonly served as nutraceuticals to post-partum women during their confinement period. Previous study showed that V. trifolia possesses high antioxidant properties that could prevent oxidative stress related diseases such as cancer, atherosclerosis, diabetes and many more. From the literature, V. trifolia leaves are used as poultice for rheumatic pains, sprains, antithelmintics and inflammations. Meanwhile, the fruits are utilised in amenorrhea. The roots, on the other hand, are used for the treatment of cough and fever. The plant is known to possess pharmacologically-active constituents such as the essential oil, halimane-type diterpenes, flavonoids, triterpenes, lignans, iridoids and ecdysteroids. Review papers were consistently published to justify the non-exhaustive biological exploration of this genus. Nevertheless, only 11 per cent of the total Vitex species were phytochemically examined. Apart from being eaten raw or blanched, Vitex is also taken as a food colourant in preparing lemuni rice. The process of making lemuni rice is quite tedious. First, the leaves and flowers are picked and washed. Both parts are then ground with water and sieved to give a bluish extract which is then mixed with rice and boiled to cook. Hence, the Vitex pouch is introduced to provide an easy way to prepare lemuni rice. This packaging is designed to enclose Vitex samples in a pouch that simply can be placed together with rice and boiled to cook. Such instant preparation will hopefully promote the consumption of lemuni rice among busy locals. Future plans include international marketing and production of other Vitex nutritional products.
Adopting Industrialisation in the Construction Environment: Meeting the Requirements of Sustainability
Authors: Musa Muhamad Faiz , Yusof Mohd Reeza , Samsudin Noor Sahidah , Muhamad Halil Faridah 
Published: March 2019

The construction industry should move from conventional construction method and adopt the industrialisation concept, to increase productivity and deliver quality construction end products. Industrialisation is the combination of a large market to divide into fractions the investment in strategies and innovation, in return, of simplifying the production and, therefore, reducing the costs. The introduction of Degree of Industrialisation by Roger-Bruno Richard is critical to the construction industry. The five degrees of industrialisation are prefabrication, mechanisation, automation, robotics and reproduction. Richard’s Degree of Industrialisation is in line with the Malaysian government’s vision to be a developed nation by 2020, to push forward the use of innovative technologies in most industries including the construction industry. The adoption of industrialisation and innovations in the Malaysian construction industry has the potential to solve the current problems in the construction industry. The problems are the inferior quality of products and processes, a poor site working conditions, low construction productivity, high construction cost, relying on foreign workers and lack of skill labours. The adoption of industrialisation and innovations promote sustainability in the construction environment. The objectives of the study are to investigate whether the adoption of industrialisation in the construction environment promotes sustainability and to identify the current level of industrialisation of the Malaysian construction industry. The methodologies of the study are semi-structure interview and observation. The Malaysian construction industry is ready to embrace industrialisation in construction environment in limited areas and industrialisation promotes sustainability in the construction environment.
Ensinando futuros professores a ensinar: reflexões de uma experiência didática
Authors: Fortunato Ivan 
Published: March 2019

O objetivo deste ensaio é analisar as atividades desenvolvidas na disciplina de didática, realizada em 2017, na licenciatura em física. Nessa disciplina, os licenciandos planejaram, executaram e avaliaram seu próprio percurso formativo, com o propósito de refletir sobre a atividade docente. Para ajudar na análise, buscou-se recuperar elementos autobiográficos, úteis no amadurecimento de uma prática pedagógica voltada ao exercício da profissão. Na sequência, a experiência didática foi descrita e analisada à luz da formação de professores. Ao final desse semestre, os licenciandos puderem evidenciar nuances do cotidiano docente, compreendendo sua complexidade e imprevisibilidade, principalmente ao experimentar a tríplice relação professor-conteúdo-aluno.
ANALYSIS OF TRAFFIC ACCIDENT VICTIMS ADMITTED TO INTENSIVE CARE UNIT IN THE PROVINCE OF KIRSEHIR FROM MAY, 01, 2016 TO MAY, 01, 2018: A RETROSPECTIVE STUDY
Authors: CANTÜRK Mehmet 
Published: March 2019

Objective: To present the epidemiologic data of traffic accident victims hospitalized at an intensive care unit.Material and Methods: Medical files of patients admitted to hospital as a traffic accident victim and hospitalized at intensive care unit from May 01, 2016 to May 01, 2018 were retrospectively analyzed. Age, gender, admission time, type of trauma, mechanical ventilation, and surgery were recorded.Results: Of the 99300 patients hospitalized due to traffic accidents, 86 patients needed intensive care unit care. Mean age of the patients was 41.80 ± 23.04 years. Fifty-five patients were male, and 31 patients were female. Sixty-two patients were under 60 years of age. Intensive care unit hospitalization was most frequent (39 patients, 45.3%) between 08:00-15:59 hours. Multiple trauma patients constituted 38.4% of the cases. Mean length of stay at the intensive care unit was 2.94 ± 4.01. Of the 86 patients; 51 were transferred to the wards, 14 transferred to a reference hospital, one discharged and 20 patients died. Conclusion: Although patients admitted to intensive care unit due to traffic accidents constitute a small percentage, they still have a high mortality rate. Increasing measures of control at times when traffic accidents are common can prevent deaths in productive age groups.
PLATELET TO LYMPHOCYTE RATIO AS A PREDICTIVE BIOMARKER FOR PREOPERATIVE DIAGNOSIS OF PARATHYROID ADENOMA
Authors: AYDIN Oktay , PEHLİVANLI Faruk 
Published: March 2019

Objective: There is a significant increase in studies concerning the use of platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR) for diagnosis and prognosis in many inflammatory and malignant diseases. The idea that PLR and NLR can be used as a biomarker attracts many researchers to this area. The aim of this retrospective case control study was to investigate the role of PLR and NLR values in diagnosis of the parathyroid adenoma.Material and Methods: In this study, 17 patients with parathyroid adenoma (PAD group) were included and the PLR and NLR values of these patients were compared with control group (15 participants) consisted of healthy subjects.Results: The lymphocyte count values of the PAD group were significantly higher than those of the CONTROL group. The platelet count and NLR values were not different between the groups. The PLR values of the PAD group were significantly lower than those of the CONTROL groups. ROC-Curve analysis results showed that if platelet to lymphocyte ratio value was &lt;125, it could be a specific and sensitive biomarker in discrimination of patients with parathyroid adenoma from healthy individuals.Conclusion: In conclusion, low PLR values measured in patients with primary hyperparathyroidism could be a new preoperative diagnostic biomarker for parathyroid adenoma.
POSTERİOR PELVİK HALKA YARALANMALARINDA HANGİ TEKNİK SEÇİLMELİDİR: PERKÜTAN SAKROİLİAK VİDA FİKSASYONU YA DA POSTERİOR PERKUTAN TRANSİLİAK PLAK FİKSASYONU?
Authors: KILINÇ Cem Yalın 
Published: March 2019

Amaç: Sakrum kırıklarının tanı ve tedavisi zor olmakla birlikte, hangi cerrahi prosedürün kullanılacağı tartışmalıdır. Amacımız, kliniğimizde sıkça kullandığımız posterior iliosakral vida ile posterior perkutantransiliak plağın uygulanabilirliğini ve postoperatif sonuçlarını karşılaştırmaktır.Gereç ve Yöntem: Haziran 2013 – Haziran 2018 arasında Muğla Sıtkı Koçman Üniversitesi Tıp Fakültesi Hastanesinde stabil olmayan posterior pelvik halka yaralanması nedeniyle opere edilen ve minimum 6 aylık takibi bulunan 29 hasta çalışmaya dahil edildi. Hasta veri/grafileri, hasta demografisi, travmanın cinsi, posterior cerrahi süresi, skopi görüntüleme sayısı, postoperatif komplikasyonlar açısından incelendi. Hastaların cerrahiden 8 hafta sonra tam yükle basmasına izin verildi. Postoperatif 3. ayda Pelvik Outcome Skor değerlendirildi. Bulgular: Pelvik Outcome Skor ile fiksasyon tipleri arasında anlamlı fark bulunmadı (p&gt;1.0). Pelvik Outcome Skor ile cinsiyet arasında anlamlı fark yoktur (p&gt;1.0). Pelvik Outcome Skor ile yaş arasında anlamlı fark saptanmamıştır (p=0.056).Cerrahi işlem süresi, posterior perkutan plak uygulanan hastalarda ortalama 35.3 dakika, perkutan vida fiksasyon uygulanan hastalarda ise ortalama 48.56 dakika (32-67 dk) olarak bulundu (p&lt;0.001). Cerrahi sırasında çekilen skopi şut sayısına bakıldığında perkutan posterior pelvik plak uygulanan grupta ortalama 2.46 şut, posterior vida fiksasyon yapılan grupta ise ortalama 37.3 şut olarak bulundu (p&lt;0.001). Sonuç: Her iki yöntem ile tedavi sonuçları benzer olarak bulunmuştur. Posterior perkutan transiliak plak fiksasyonu kullanılan hastalarda, ameliyat süresi daha kısa olup skopiye maruziyet oldukça azdır.
THE INFLAMMATION OF EPIPLOIC APPENDIX: PRIMARY EPIPLOIC APPENDAGITIS
Authors: VURAL Sevilay , COŞKUN Figen 
Published: March 2019

Epiploic appendices are extensions of omentum which covers most of the colon. Most of the pathologic changes are related with spontaneous torsion or venous thrombosis culminating with inflammation and is referred as primary epiploic appendagitis (PEA). There is no pathognomonic symptom, finding or laboratory test for this relatively rare intra-abdominal inflammation. A non-toxic patient with acute onset localized abdominal pain in the right or left lower quadrant is the typical presentation. Imaging studies such as ultrasound and tomography with the awareness of PEA in differential diagnoses of intra-abdominal pathologies are the key to correct diagnosis. Since the conservative treatment is sufficient in most of cases, accurate and timely diagnosis can ensure the appropriate patient management and can prevent unnecessary hospitalizations and interventions.
Max Schelers Reformation der Religionsphilosophie
Authors: Gaitsch Peter 
Published: March 2019

Max Scheler's Reformation of Philosophy of Religion The following contribution aims to show the relevance of Max Scheler's reflections on the relation of Christianity and modernity for the present situation. It interprets Scheler's philosophy of religion in terms of a principle of reformation that can be implicitly found in Scheler's critical assessment of the historical impact of Lutheran Protestantism. Scheler's principle of reformation provides four criteria: (i) autonomy of the religious sphere, (ii) dialectics of life and spirit, (iii) community beyond religious denominations, and (iv) metaphysical determination of the divine. On that basis, we will see that Scheler's "catholic” phenomenology of religion from 1921 only partly meets his own criteria, whereas his "post-catholic” metaphysics of panentheism, developed after 1922, is more suitable to meet these criteria. Two factors are crucial: First, the divine is characterized by a fundamental metaphysical tension between spirit and vital impulsion, which leads to transferring the responsibility of balancing this tension to the history of mankind. Second, the community that corresponds to this metaphysical conception is not delimited by religious denomination but is integrated by solidarity among all human and living beings instead.
EFEKTIVITAS LAYANAN KONSELING KELOMPOK TEKNIK MANAJEMEN DIRI UNTUK MENINGKATKAN SELF-ESTEEM SISWA
Authors: Yuliastini Ni Komang Sri , Mahaardhika I Made 
Published: March 2019

<p>Tujuan penelitian ini adalah mengetahui kondisi <em>self-esteem </em>siswa dan mengetahui keefektifan layanan konseling kelompok teknik manajemen diri untuk meningkatkan <em>self-esteem</em> siswa kelas X SMK PGRI 1 Denpasar. Jenis penelitian ini adalah penelitian kuantitatif.Penelitian ini melibatkan 6 siswa sebagai sampel. Berdasarkan hasil uji lapangan, tingkat <em>self esteem</em> siswa mengalami peningkatan setelah mengikuti kegiatan konseling kelompok dengan teknik manajemen diri. Ditunjukkan dengan perubahan tingkat efikasi diri siswa sebelum diberikan perlakuan (evaluasi awal) dan sesudah (evaluasi akhir) sebesar 103 poin. Hasil didukung data hasil perhitungan dengan uji rata-rata uji <em>wilcoxon</em> yang menunjukkan nilai hitung 0,026 sehingga dapat disimpulkan bahwa layanan konseling kelompok dengan teknik manajemen diri efektif untuk meningkatkan <em>self esteem</em> siswa.</p>
“Tıp terimleri” üzerine yapılan çalışmalar hakkında bir bibliyografya denemesi
Authors: Murad Sibel 
Published: March 2019

Türk dilinin terim yaratmadaki gücünü gösterdiği
eserler arasında şüphesiz bilim tarihi eserleri önemli bir yere sahiptir.
Birçok farklı bilim dalında telif ve tercüme eser veren Türk dilinin, terim
üretmedeki çeşitliliğini izleyebildiğimiz bilim eserlerinden biri de tıp konulu
metinleridir. Müstakil olarak tıp konusunu ele alan eserler yanında, içeriğinde
tıp terimleri bulunan, farklı konularda yazılmış birçok eser bulunmaktadır.
Günümüze kadar tıp metinleri, tıp sözlükleri ve tıp terimleri üzerine birçok
çalışma yapılmış olup, halen tıp metinleri, tıp sözlükleri ve tıp terimleriyle
ilgili çalışmalar yapılmaya devam etmektedir. Bugüne kadar yapılmış
çalışmaların bir kısmı doğrudan tıpla ilgili olmayan eserlerdeki tıp terimleri
üzerineyken, bir kısmı da doğrudan tıp konulu eserlerdeki terimlerle ilgilidir.
Tıp terimleri kavramının içine dâhil edilen ilaç, tıpta kullanılan bitkiler,
hayvansal-madensel maddeler, insan ve hayvan organları; hastalıklar, tedavi yöntemleri,
tıbbi aletler gibi birçok terimle ilgili çalışmalar yapılmıştır. Çalışmalar
“tıp terimli” başlıklı olanlar, tıp terimlerinden herhangi birini konu
edinenler ve terimler için önemli bir kaynak olan sözlükler üzerinde
yoğunlaşmıştır. Bu
çalışmada günümüze kadar tıp terimleri üzerine yapılan çalışmalar ortaya
konacak, bunlardan bazıları özetlenerek açıklanacaktır. Böylece tarihi tıp
metinleriyle ve tıp terminolojisiyle ilgilenen bilim insanlarına bu alanda
yapılan çalışmalar hakkında bilgi verilecek, hangi konuların ele alındığı
ortaya konarak henüz üzerinde çalışılma yapılmayan konular hakkında
araştırmacılara fikir sağlanacaktır.
Hayattan esere: Ahmet Hamdi Tanpınar’da yeme-içme kültürü
Authors: Güreşir Salih Koralp 
Published: March 2019

Hayatla doğrudan ilgili olan edebiyat, yeme-içme
kültürü ile de bu çerçevede ilgilenir. Yeme-içme, bireyin biyolojik bir
ihtiyacı olduğundan başka mensubu bulunduğu kültürün önemli bir ögesidir. Köklü
mazisinden kaynaklanan zengin içeriği ile Türk mutfağı yazarlarımıza oldukça
geniş imkânlar sunmuştur. Refik Halit Karay, Ahmet Rasim ve Ahmet Midhat Efendi
başta olmak üzere birçok yazar, bu imkânlardan yararlanıp yeme-içme unsurlarını
edebî eser formunda vermişler, böylelikle Türk mutfak kültürünün edebiyat
vasıtasıyla da devamını sağlamışlardır. Bir kültür ve sanat insanı olarak
hayata geniş bilgisi ve görgüsü etrafından bakan Ahmet Hamdi Tanpınar da
edebiyatla yeme-içmenin münasebetine ilgisiz kalmaz. Hem bize hayatını veren
günlükleri ve mektuplarında hem de geniş kültürünü yansıtan kurgusal
metinlerinde yeme-içmeye türlü açılardan dikkat eder. Günlükleri ve
mektuplarında yeme-içme özelinde insani tarafından yakaladığımız yazar,
kurgusal metinlerinde meseleye millî kültüre yönelttiği estetik bakışlarla
yönelir. İkinci tipteki eserlerinde yeme-içmeye dair verdiği ayrıntılar aynı
zamanda kurguya katkı yapıcı işlevde kullanılmıştır. Kalabalık şahıs kadrosuna
sahip romanlarında karakterleri bir araya toplama, eserde tartışılan meselelerin
bir kez daha üstünden geçme, bir karakteri tanıtma, estetiğinin büyük kısmını
oluşturan musikiye değinme fırsatı bulma gibi gayelerle yazar, eserlerinde
sofra ve kültürüne yer vermiştir. Tüm bunlar konunun edebiyatla ilgisini Tanpınar
gibi büyük bir yazarın kalemiyle kanıtlamaktadır.&nbsp;