bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aquatic Ecological Landscape Planning Based on Numerical Modelling
Authors: Chen Xianyuan 
Published: December 2024

Abstract

Urban waterbody landscape planning necessitates the dual objectives of water quality improvement and landscape optimization to create a favorable aquatic ecological landscape environment. Taking Canghai Lake in Guangxi as a case study, the MIKE 21 hydro-environment simulation software was employed to establish a two-dimensional hydrodynamic and water quality model for the lake area. This model was utilized to simulate the flow and water quality conditions within the lake, and to propose an overall strategy for enhancing hydrodynamics and improving water quality in the lake area. The study findings indicate that incorporating an artificial wetland at the lake inlet within the planning, by appropriately configuring emergent, floating, and submerged plants, can construct an efficient plant ecosystem. This approach is expected to reduce the phosphorus load entering the lake by over 45%, effectively improving the water quality in the lake area, and fundamentally eliminating the risk of large-scale algal bloom outbreaks in Canghai Lake. Additionally, it will create a wetland landscape, thereby achieving an organic unity of water quality enhancement and landscape optimization. An integrated planning method for lake ecological landscapes that combines water quality simulation, aquatic ecosystem restoration, and water landscape planning technologies is proposed, which can serve as a reference for the planning and design of urban waterbody landscapes.
How does China’s HSR development affect urban-rural income inequality? Based on the enterprise productivity perspective
Authors: Yu Guohua , Qi Yingying , Ren Yimeng 
Published: December 2024

Abstract

The rapid development of high-speed rail (HSR) is an important manifestation of transportation modernization in China. This paper investigates the impact of HSR on enterprise productivity and urban-rural income inequality by matching HSR, China’s A-share listed enterprises, and data in Chinese prefecture-level and above cities. In theory, HSR has gathered a large amount of human capital to improve enterprise productivity, continuously promoting labor transfer from rural areas to cities and from inefficient enterprises to high-efficiency enterprises, thereby suppressing urban-rural income inequality. HSR can significantly promote the effect on enterprise productivity and suppress the degree of urban-rural income inequality through enterprise productivity. Further analysis reveals that the impact of HSR on enterprise productivity and urban-rural income inequality is heterogeneous based on different types of enterprises and industries. Specifically, the effect of HSR on suppressing urban-rural income inequality is more significant in non-SOEs and non-technical intensive industries.
Declining Boswellia serrata population in Eastern India: The interplay of climate change and socioeconomic influences
Authors: Kumar Raj , Tiwari Sharad 
Published: December 2024

Abstract

Comprehending the impact of climate change on species' habitats is essential for their conservation and management strategies. Climate change causes plant species' habitats to contract, resulting in population losses, and habitat modeling is an effective instrument for examining this. Nevertheless, most studies have concentrated on climate scenarios depicted by the Representative Concentration Pathways. Moreover, these studies frequently need more ground validation and incorporate phytosociological assessments to enhance understanding plant dispersal dynamics. This work addresses these deficiencies by incorporating comprehensive field surveys, doing a phytosociological assessment of the area, and employing shared socioeconomic pathways (SSPs) as proxy pathways. We modeled the potentially suitable habitats for the endangered medicinal tree Boswellia serrata Roxb. ex Colebr in the Jharkhand state of subtropical eastern India. Employing Maxent, we forecasted the probable suitable habitat range of B. serrata for both current and future climate scenarios, specifically IPSL-CM6A-LR, MIROC6 and MPI-ESM1-2-HR as represented by SSP 126, 245, 370, and 585. The study indicated that roughly 16,348 km² (~ 20.51% of the study area) currently functions as a suitable habitat for B. serrata. The findings reveal a projected drop of 14.25 to 15.97% in the region's appropriate habitat range of B. serrata by 2060. The species may face local extinction in northeastern Jharkhand, as it is restricted to the northern region. The findings have substantial significance for research and conservation practices, offering fresh insights into the distribution ecology of B. serrata and pinpointing priority regions for conservation efforts.
Predictive factors and one-year outcomes following successful contemporary chronic total occlusions percutaneous coronary interventions
Authors: Jin Li , Genrui Chen , Huan· Wang , Youhu Chen , Lei Xiaolin , Chengxiang Li , Haokao Gao 
Published: December 2024

Abstract

Background: We aimed to explore the predictive factors and one-year clinical outcomes following successful contemporary CTO-PCI.
Methods:Consecutive patients from January 2018 to December 2020 were enrolled. The primary endpoint was major adverse cardiovascular events (MACE) which included all-cause death and myocardial infarction, while target vessel revascularization (TVR) was defined as the secondary endpoint, all of which were measured at 12 months.
Results:A total of 830 patients were treated by successful CTO PCI, and 96.7% of these cases were available with one-year follow-up data (n=803). The incidence of MACE was observed in 27 patients (3.4%), with all-cause death occurring in 21 cases (2.6%) and myocardial infarction in 6 cases (0.7%). TVR occurred in 35 patients (4.4%). The multivariate predictive factor analysis for MACE indicated that LVEF <40% (P=0.007) and residual SYNTAX score ≥ 12 (P<0.001) were identified as independent risk factors for MACE. While prior PCI (P=0.017) and aspirin usage at discharge (P<0.001) were protective factors. Parallelly, prior PCI (P=0.003), ambiguity proximal cap (P=0.006), and guide-wire manipulation time (GMT) (P=0.008) were independent risk factors for TVR, while LAD-CTO presence (P=0.045) and stent implantation (P=0.001) were protective factors.
Conclusion: Patients deserved favorable outcomes and a low incidence of adverse events after one year following successful contemporary CTO PCI.
Clinical validation of non-invasive blood glucose measurements by mid-infrared spectroscopy
Authors: maentele Werner , Kaluza Michael , Janik Sergius , Lubinski Thorsten , Saita Mattia , Lachmann Peter , Canini Luca , Lepro Valentino 
Published: December 2024

Abstract

Non-invasive glucose monitoring (NIGM) is considered the holy grail of diabetes technology. Currently, diabetes is predominantly managed based on finger pricking and analysis of a drop of blood with test strips fitting into a glucometer. This invasive, painful and uncomfortable procedure is one of the reasons for insufficient diabetes management. Sensors for continuous glucose monitoring (CGM) in interstitial fluid (ISF) using a subcutaneous microscopic filament present a minimally-invasive alternative. A true NIGM is not available yet despite intense research and development. DiaMonTech has demonstrated a NIGM technology that targets glucose in ISF. An infrared beam from a quantum cascade laser excites glucose molecules at wavelengths between 8 and 12 µm, where glucose has specific fingerprint absorbance. Absorption results in a small amount of heat in the skin, which can be detected on the surface using a photothermal deflection technique. This procedure is painless, harmless, and does not require consumables. We report here a single-center clinical test with 36 individuals. The accuracy of the NIGM device was evaluated in two subsequent sessions per individual, with different amounts of calibration data. Four different algorithms were tested for data analysis. The accuracy for the best algorithm, expressed as Mean Absolute Relative Difference was 20.7% and 19.6% for the two sessions. This is equivalent to the performance of early CGM systems cleared by the FDA for adjunctive use by people with diabetes. It demonstrates that glucose can be reliably measured with this non-invasive technology and opens new perspectives for a better management of diabetes.
Fast detection of uric acid in urine for early diagnosis using THz polarised waves
Authors: Mazaheri Zahra , Federico Giorgia , Koral Can , Papari Gian Paolo , Ullatil Lakshmi , Russo Paolo , Andreone Antonello 
Published: December 2024

Abstract

Towards new and improved techniques in liquid biopsy for diagnosis of diseases, this study reports experimental evidence of a rapid and reliable method based on terahertz (THz) time-domain spectroscopic ellipsometry (TDSE) for early diagnosis of kidney-related diseases, by detecting uric acid (UA) in urine. By measuring absorption and dispersion spectra of urine samples, the potential of THz-TDSE for non-invasive, accurate detection of UA as a urinary biomarker is investigated. Employing a custom-built THz-TDSE system, we analysed the absorption response of synthetic urine samples with varying concentrations of UA. The technique provides prompt indication of UA presence and concentration, thanks to the sensitivity of THz waves to intermolecular interaction such as hydrogen bonding. The results show in the frequency window 0.2¸1.2 THz a linear correlation between UA concentration and changes in the absorption spectra of urine, with the minimum detectable UA concentration being approximately close to the upper limit of normal UA levels in urine. The increase of the absorption coefficient as a function of the UA concentration provides a means for a quantifiable measure of the UA biomarker in urine for assessing disease stage. The study confirms that THz-TDSE is capable of detecting UA at concentrations relevant for early-stage diagnosis of renal diseases. Moreover, we estimate a sensitivity of 0.2 g/L in the region where the material response is linear.
Novel Biomarkers for Lymph Node Metastasis and Prognosis of Bladder Cancer by Bioinformatics Analysis
Authors: yifan sun , Ding Meng , Sun Jiyuan , Zhang Qing , Cao Wenming , Chen Wei , Wang Xinping , Diao Wenli , Guo Hongqian 
Published: December 2024

Abstract

Lymph node (LN) metastasis is related to poor prognosis in bladder cancer (BLCA). To explore novel signature genes associated with LN metastasis in BLCA, we identified 17 signature genes with non-zero coefficients to construct the prognostic model, which demonstrated a prognostic accuracy with an area under the curve of 0.706 at 1 year, 0.701 at 3 years, and 0.688 at 5 years. FKBP10 and EPN2, two of the above signature genes, exhibited significant upregulation in BLCA with LN metastasis, thereby contributing to the unfavorable survival of BLCA patients. Moreover, by utilizing the CIBERSORT algorithm and immunofluorescence assay, we identified and validated a significant upregulation of M0 macrophages, alongside a downregulation of activated NK cells and CD8+ T cells, which were associated with the presence of LN metastasis in BLCA. Conclusively, These results will provide new insights for future improvements in diagnosis, treatment, and prognosis evaluation for BLCA patients with LN metastasis.
Strengthening evidence syntheses with adolescent involvement: an umbrella review
Authors: Warraitch Azza , Sulowska Matylda , Wacker Ciara , Lee Maria , Bruce Delali , Hernon Joshua , Khraisha Qusai , Hadfield Kristin 
Published: December 2024

Abstract

Background
Stakeholder involvement in evidence syntheses has been shown to enhance the quality and relevance of reviews. Despite the critical role adolescents can play in shaping their health outcomes, they remain underrepresented in contributing to reviews on topics that directly affect them. To fully unlock the potential of evidence syntheses for adolescent health, it is crucial to understand how adolescents can contribute at various stages of the review process and how their involvement can influence outcomes.
Methods
To achieve this, we conducted an umbrella review examining adolescent involvement in reviews related to adolescent health research, complemented by a case study that highlights how adolescents were engaged at various stages of this review. We ran a search across 11 databases, screened reference lists and twelve journals, and consulted experts in youth involvement.
Results
We found only 10 reviews which meaningfully involved adolescents. In those reviews, adolescents were engaged at almost every stage of the review process, with most involvement centred around interpreting findings or co-authoring the final reports. While adolescent participation was often consultative, there were examples of more collaborative involvement using a wide range of methods, even at technical stages like study selection and data analysis.
Conclusion
The findings highlighted the potential for adolescents’ input to improve the quality and outcomes of evidence syntheses by grounding the process and findings in their experiences and insights. To maximise the impact of adolescent involvement, we call for engagement of adolescents throughout the review process and the adoption of frameworks to ensure transparency and consistency in reporting.
Systematic review registration:
PROSPERO (CRD42021287467)
Biometric and physiological responses of Virola Surinamensis to cadmium and biochar in amazonian soil
Authors: Braga Dayse Gonzaga , Ferreira Raphael Leone da Cruz , Silva Camylle Barbosa da , Cabral Joyce Adriany da Costa , Alves Anne Cristina Barbosa , Brito Ana Ecídia de Araújo , Nascimento Vitor Resende do , de Souza Luma Castro , Neto Cândido Ferreira de Oliveira 
Published: December 2024

Abstract

Objective of this study was to assess the mitigating effects of biochar derived from açaí seeds on the biometric and physiological responses of Virola surinamensis plants grown in soil contaminated with cadmium. Experiment was conducted in a controlled greenhouse environment, utilizing V. surinamensis seedlings grown in soils contaminated with varying concentrations of Cd (0, 10, 20, and 30 mg L− 1) and different biochar proportions (0%, 5%, and 10%). Statistical analysis was performed using the F-test, and when significant, the Tukey test was applied. At a Cd concentration of 10 mg L− 1, the number of leaves was greater in the absence of biochar application; however, this did not significantly differ from the treatment containing 5% biochar. In terms of the chlorophyll an index, the application of 5% biochar was the most effective in maintaining the chlorophyll content in the presence of Cd. Furthermore, for plants exposed to 10 and 20 mg L− 1 of Cd, the inclusion of 5% biochar mitigated the toxic effects of the metal, leading to increased rates of photosynthesis. Plants treated with 20 mg L− 1 of Cd also presented higher transpiration rates with 5% biochar application. For intercellular CO2 concentrations, soils contaminated with 10 mg L− 1 of Cd demonstrated an increase in carbon concentration when treated with biochar. Thus, the addition of 5% biochar was effective in attenuating the toxic effects of cadmium on biometric parameters, photosynthetic pigments, and transpiration rates in V. surinamensis plants, suggesting its potential as a mitigation strategy for cadmium-contaminated soils.
Exploring Vacuum Erection Device User Feedback: A GPT-4 Thematic Analysis
Authors: Breyer Benjamin , Patel Hiren , Abbasi Behzad , Li Kevin , Carlisle Marvin , Faris Anna , Pace William 
Published: December 2024

Abstract

Vacuum erection devices (VEDs) are commonly recommended by urologists to treat erectile dysfunction. We explored consumer views on VED use through a qualitative analysis of 1,500 Amazon.com reviews for 21 of the most popular VED products. Reviews were analyzed using GPT-4, identifying common themes and subthemes. Electric and manual VEDs were compared, and a multivariable ordinal regression was built to identify factors linked to higher product ratings. The most common themes were efficacy (1,375/1,500, 92%) and user experience (82%). Electric VEDs compared to manual devices had more frequently mentions of ease of use (46% vs. 34%) and better design features (26% vs. 17%). A 5/5 rating was linked to fewer mentions of deficiencies, malfunctions, warnings, and desired changes compared to 1/5 rating. Each 1 USD increase was linked to an average 0.10-point drop in ratings (95% CI: -0.12 to -0.08). Compared to non-electric, non-sex toy products, those with electric features and additional sex toy functions had average rating increases of 0.72 points (95% CI: 0.44 to 1.00) and 0.40 points (95% CI: 0.13 to 0.67), respectively. Amazon reviews generally show positive sentiment towards VEDs, with electric models favored for ease of use, though patient education is essential for safe use.
The influence of total intravenous anesthesia on perioperative fatigue in patients undergoing stent implantation for cerebrovascular stenosis
Authors: Zhang Xiaoxiao , Bai Yang , Wu Youxuan , Wu Bei , Liu Haiyang , Han Ruquan 
Published: December 2024

Abstract

Objective: To explore the influence of total intravenous anesthesia on the occurrence of perioperative fatigue in patients with cerebrovascular stenosis who undergo elective stent implantation on an elective basis.
Methods: Patients who underwent elective stent implantation for cerebrovascular stenosis in the Neuro-interventional Center of Beijing Tiantan Hospital, Capital Medical University were continuously included from November 2021 to March 2022. Demographic information, peripheral blood biomarkers, scale information, and information related to surgical anesthesia of the patients during the perioperative period were collected.
Results: One day after the operation, more patients in the general anesthesia group were diagnosed with perioperative fatigue (14 (70%) vs. 4 (20%), P = 0.001) than in the local anesthesia group, and the severity was higher (7.0 ± 3.8 vs. 4.5 ± 2.9, P = 0.025). The proportion of patients with perioperative fatigue who received total intravenous anesthesia was higher than that in the non-fatigue group (6 (27.3) vs. 14 (77.8), P = 0.001), the decrease in norepinephrine levels was greater (0.05 (-0.03, 0.13) vs. -0.10 (-0.17, -0.04), P = 0.001), the decrease in serotonin levels was more obvious (-0.07 (-0.23, 0.22) vs. -0.19 (-0.30, -0.11), P = 0.035), while there was no significant statistical difference in dopamine levels. The levels of changed monoamine neurotransmitters one day and seven days after the operation were negatively correlated with the score of the Fatigue-14 Scale.
Conclusion: The incidence of perioperative fatigue is relatively high. Total intravenous general anesthesia may increase the occurrence of perioperative fatigue. In addition, the levels of monoamine neurotransmitters, especially norepinephrine, may be related to the occurrence of perioperative fatigue.
Study on the prediction of AMH levels in women of reproductive age based on multiple linear regression analysis
Authors: Si Xing , He Xuewei 
Published: December 2024

Abstract

Objective
To construct a predictive model for AMH levels in women of reproductive age using multiple linear regression analysis.
Methods
A retrospective study was conducted involving 492 patients who underwent ovarian reserve function tests at Hangzhou Traditional Chinese Medicine Hospital. The patients were randomly divided into a training set (n = 420) and a validation set (n = 72). All subjects underwent transvaginal 3D ultrasound to measure AFC, OV, PSV, and RI. Additionally, fasting venous blood samples were collected on days 2–5 of the menstrual cycle for AMH level testing. Pearson correlation analysis was used to assess the relationship between age, AFC, OV, PSV, RI values, and AMH. Multiple linear regression analysis was employed to construct both a unified regression model and a subgroup regression model for prediction. Model performance was evaluated by comparing RMSE and MAE.
Results
AMH showed a negative correlation with age and positive correlations with OV, AFC, and PSV. The RMSE and MAE of the subgroup regression prediction model were lower than those of the unified regression prediction model.
Conclusion
The subgroup regression AMH prediction model developed through multiple linear regression analysis performs well and can provide accurate individualized predictions.
Simulated learning interventions to improve communication and practice with deaf and hard of hearing patients: a systematic review and qualitative synthesis
Authors: Terry Julia , Wilks Rachel , Davies Joanne 
Published: December 2024

Abstract

Virtual and simulated patients are increasingly used in health professional education as learning about patient needs in a safe space greatly benefits student knowledge and skills and increases their empathy towards patients. Yet to date there has been limited focus on using simulated learning techniques in health professional education to promote learning about D/deaf and hard of hearing patients. We used systematic review methodology to search, identify, appraise and abstract relevant articles across CINAHL, MEDLINE, ASSIA and Proquest Central, Scopus, Web of Science and Cochrane databases yielding a total of 1112 papers. After removing duplicates, inclusion criteria were defined and applied, resulting in 132 articles retrieved for full-text review. Six articles met all inclusion criteria, addressing simulated learning methods for health professional students that provide educational opportunities about Deaf patient experiences. Findings suggest that a myriad of possible simulation modalities can be developed that include opportunities to learn about the D/deaf patient experience and to consider learning about communication and application of knowledge to a specific topic environment. This qualitative synthesis provides insight into potential methods and styles of delivery, whilst noting a very small number of studies in this area. Future research should focus on rigorous and longitudinal studies to understand more about student learning and how interventions impact on their communication and encounters with D/deaf patients.
Relationship Between Land Cover and Land Surface Temperature: Example of Eski̇şehi̇r City Center
Authors: Koca Seda , Menteşe Serpil 
Published: December 2024

Abstract

The increase in residential areas in line with the needs of the increasing population and dense urban settlement affect many physical and human elements, especially the urban climate. Especially the materials used in urban spaces and on the land, the quality and quantity of the buildings, and the settlement structure that is not suitable for natural environmental conditions cause differences in land surface temperatures. In this study, it is targeted to evaluate the effect of change in land cover on land surface temperatures in the city center of Eskişehir province. For this purpose, the years 1990 and 2018 were considered, and summer and winter data of Landsat 5 TM and Landsat 8 OLI/TIRS satellite images were used. It was concluded that from 1990 to 2018, agricultural lands decreased in area, places with agricultural land were replaced by settlement texture, and especially industrial and commercial units grew in area. This change in land cover has affected the amplitude of land surface temperatures. It was determined that the amplitude of land surface temperatures increased in the study area in both summer and winter. While high land surface temperatures in winter are detected outside the urban settlement boundaries, especially in agricultural lands, in summer they are detected in the city, especially on open and bare surfaces. It is thought that the seasonal humidity of the land, the presence of products in agricultural lands and the heating-cooling characteristics of the materials used in the city are effective on this situation.