bluuebunny/crossref_metadata_2025_split huggingface dataset:
Iron, Hepcidin, and Death in Human AKI
Authors: Leaf David E. , Rajapurkar Mohan , Lele Suhas S. , Mukhopadhyay Banibrata , Boerger Emily A.S. , Mc Causland Finnian R. , Eisenga Michele F. , Singh Karandeep , Babitt Jodie L. , Kellum John A. , Palevsky Paul M. , Christov Marta , Waikar Sushrut S. 
Published: February 2019

Significance Statement
Dysregulated iron metabolism plays an important pathogenic role in AKI in animal models, but limited data are available on circulating iron parameters in human AKI. To assess the association of plasma catalytic iron, total iron, transferrin, TSAT, ferritin, free hemoglobin, and hepcidin with 60-day mortality, the authors examined observations in a cohort study of 807 critically ill patients with AKI (all requiring RRT) who were enrolled the ARF Trial Network study. They found that higher concentrations of catalytic iron and lower concentrations of hepcidin are each monotonically and independently associated with increased mortality. These findings identify plasma catalytic iron and hepcidin as potentially useful prognostic markers or therapeutic targets in patients with AKI requiring RRT.

Background
Iron is a key mediator of AKI in animal models, but data on circulating iron parameters in human AKI are limited.

Methods
We examined results from the ARF Trial Network study to assess the association of plasma catalytic iron, total iron, transferrin, ferritin, free hemoglobin, and hepcidin with 60-day mortality. Participants included critically ill patients with AKI requiring RRT who were enrolled in the study.

Results
Of the 807 study participants, 409 (51%) died by day 60. In both unadjusted and multivariable adjusted models, higher plasma concentrations of catalytic iron were associated with a significantly greater risk of death, as were lower concentrations of hepcidin. After adjusting for other factors, patients with catalytic iron levels in the highest quintile versus the lowest quintile had a 4.06-fold increased risk of death, and patients with hepcidin levels in the lowest quintile versus the highest quintile of hepcidin had a 3.87-fold increased risk of death. These findings were consistent across multiple subgroups. Other iron markers were also associated with death, but the magnitude of the association was greatest for catalytic iron and hepcidin. Higher plasma concentrations of catalytic iron and lower concentrations of hepcidin are each independently associated with mortality in critically ill patients with AKI requiring RRT.

Conclusions
These findings suggest that plasma concentrations of catalytic iron and hepcidin may be useful prognostic markers in patients with AKI. Studies are needed to determine whether strategies to reduce catalytic iron or increase hepcidin might be beneficial in this patient population.
LCD codes and LCP of codes from units of group rings
Authors: KÖROĞLU Mehmet Emin 
Published: February 2019

A linear code with complementary dual
(LCD) is a linear code such that LCD codes are of great
importance due to their wide range of applications in consumer electronics,
storage systems and cryptography. Group rings have a rich source of units. Also
the well-known structural linear codes such as cyclic codes are within the
family of group ring codes. Thus, group rings offer an affluent source for
structural codes that may lead to linear codes with good properties. In this
work, we derive a condition for codes obtained from units of group rings to be
LCD. We show that a special decomposition of group rings meet the LCD
condition. We also proposed a consruction of linear complementary pair (LCP) of
codes.
Some remarks for a certain class of holomorphic functions at the boundary of the unit disc
Authors: ÖRNEK Bülent Nafi , AKYEL Tuğba 
Published: February 2019

We consider a boundary version of the Schwarz Lemma on a certain class which isdenoted by K(alfa) . For the function f(z)=z+c2z2+....... which is defined in the unit disc Esuch that the function f (z) belongs to the class K(alfa) , we estimate from below the modulus of theangular derivative of the function ( )( )zf ' zf zat the boundary point b with ( ) = 1( ) 1bf ' bf b . Moreover,we get the Schwarz Lemma for the class K(alfa) . We also investigate some inequalities obtained interms of sharpness.
Pengembangan Kualitas Pengkaryaan Sanggar Seni Kembhâng Moljâ Melalui Keterampilan Perekaman Audio Untuk Meningkatkan Potensi Kesenian Di Situbondo
Authors: Hidayatullah Panakajaya 
Published: February 2019

Kegiatan ini merupakan program pengabdian yang berfokus pada pengembangan kualitas individu dan kelompok sanggar Kembhâng Moljâ di Situbondo, secara konkret berupaya untuk menyelesaikan masalah-masalah yang terjadi di dalam sanggar tersebut, melalui 1) Pelatihan tentang pendokumentasian karya (audio recording) secara metodis dan teoritis; 2) Dari hasil pelatihan diharapkan dapat langsung diterapkan menjadi media pembelajaran, sehingga dapat mengoptimalkan proses kreatif pengkaryaan, dan bisa ditransformasikan ke khalayak luas; 3) Memberikan metode dan konsep tetang pengembangan karya seni khususnya dalam konsep perekaman karya (audio-visual). Hasil yang dicapai dari kegiatan pendampingan ini ialah sebuah pengembangan sumber daya manusia dalam sanggar seni Kembhâng Moljâ. Para anggota sanggar seni Kembhâng Moljâ yang mengikuti pelatihan, mendapatkan sebuah pemahaman tentang, 1) Pengetahuan perekaman audio, prinsip-prinsipnya serta teknis mengerjakannya; 2) Keterampilan dalam merekam karya secara profesional yang terbagi dalam tiga tahapan yakni tracking-recording, mixing, dan mastering; 3) Membuat media pembelajaran berbasis rekaman.
Kata Kunci: pengembangan kualitas, sanggar seni, dokumentasi karya, Situbondo
KEMAMPUAN BERFIKIR FORMAL SISWA SMA DITINJAU DARI GAYA KOGNITIF FIELD DEPENDENT DAN FIELD INDEPENDENT
Authors: Nurhardiani Nurhardiani , Syawahid Muhammad 
Published: February 2019

Tujuan penelitian ini untuk mendeskrifsikan gaya kognitif field independent dan field dependent siswa SMA ditinjau dari jenis kelamin siswa. Siswa diminta untuk mengerjakan tes GEFT dan soal kemampuan matematika kemudian diwawancarai. Indikator yang digunakan untuk mengukur kemampuan berpikir formal adalah: (1) mampu memberikan alasan disetiap langkah yang dilakukan hingga memperoleh kesimpulan dengan benar, (2) mampu memberikan alasan disetiap langkah yang dilakukan hingga memperoleh kesimpulan kurang tepat atau terdapat kesalahan, (3) tidak dapat memberikan alasan disetiap langkah yang dilakukan. Dari hasil penelitian, diperoleh dari 66 siswa yang diberikan tes GEFT, terdapat 30 siswa dengan gaya kognitif field independent dan 36 siswa dengan gaya kognitif field dependent. Dari 30 siswa dengan gaya kognitif field independent diperoleh 2 siswa dengan kemampuan berpikir formal sangat baik berarti hanya 7%, 19 siswa dengan kemampuan berpikir formal baik berarti 63%, dan 9 siswa dengan kemampuan berpikir formal cukup baik berarti 30%. Sedangkan yang dari 36 siswa dengan gaya kognitif field dependent diperoleh 6 siswa dengan kemampuan berpikir formal cukup baik artinya 16% dan 30 siswa dengan kemampuan berpikir formal kurang artinya 84%. Kemampuan berpikir formal sangat baik ditunjukkan dengan kemampuan memberikan alasan disetiap langkah yang dilakukan hingga memperoleh kesimpulan yang benar pada dua soal yang diberikan. Kemampuan berpikir formal baik ditunjukkan dengan kemampuan memberikan alasan disetiap langkah yang dilakukan hingga memperoleh kesimpulan kurang tepat atau terdapat kesalahan pada salah satu soal yang diberikan. Kemampuan berpikir formal cukup baik ditunjukkan dengan kemampuan memberikan alasan disetiap langkah yang dilakukan hingga memperoleh kesimpulan kurang tepat atau terdapat kesalahan pada dua soal yang diberikan. Kemampuan berpikir formal kurang baik. ditunjukkan dengan ketidakmampuan siswa dalam memberikan alasan disetiap langkah yang diberikan.
Exigencias emocionales y la construcción de la identidad en el trabajo de cuidado
Authors: Galeano Patricia S. 
Published: February 2019

Se exponen aquí algunos resultados de investigación desarrollada en la Facultad de Ciencias Económicas de la Universidad Nacional de La Plata, dirigido por el Dr. Julio C. Neffa en el año 2016. La misma evaluó los riesgos psicosociales del trabajo (RPST) y medio ambiente, en una Clínica de Salud Privada en la ciudad de La Plata. El marco teórico está desarrollado en publicaciones recientes (Neffa, 2015 y Neffa et al, 2017) y para el relevamiento de la información se aplicó el Cuestionario sobre riesgos psicosociales aplicable en Argentina. La muestra es no probabilística, contempla los diferentes agrupamientos y categorías profesionales. Es de interés en este artículo, reflexionar y aportar datos sobre las relaciones entre las exigencias emocionales en el trabajo y la construcción de la identidad laboral, en una actividad que concierne al trabajo de cuidado y donde prima el trabajo emocional.
Effect of acupuncture on insomnia in menopausal women: A Study protocol for a Randomized Controlled Trial
Authors: Li Shanshan , Yin Ping , Yin Xuan , Bogachko Anna , Liang Tingting , Lao Lixing , Xu Shifen 
Published: February 2019

Abstract
Background: China today has high occurrences of insomnia in perimenopausal women. Some studies have shown that acupuncture might be effective in treating primary insomnia and insomnia related to depression and stroke. Although there are some programs supporting insomnia during the menopausal transition, there are few randomized controlled trials to provide evidence regarding their effectiveness. We design a randomized controlled trial of suitable sample size to verify the effectiveness of acupuncture in patients with insomnia during the menopausal transition and to form an optimized acupuncture treatment protocol.
Method: In this randomized, single-site, single-blind, placebo-controlled trial, 84 eligible patients will be recruited and randomly assigned to either the acupuncture group (n = 42) or the sham control group (n = 42) in a 1:1 ratio. Participants will receive a total of 18 sessions of treatment for eight consecutive weeks. Treatments will be given three times per week in the first four weeks, twice a week for the next two weeks and finally treatment once weekly for the final two weeks. Treatment will utilize eight main acupoints (GV20, GV24, GV29, RN6, RN4, SP6, HT7, EX-HN22), and extra two acupoints based on syndrome differentiation. The primary outcome will be assessed using the Pittsburgh Sleep Quality Index (PSQI). The secondary outcomes will be measured by sleep parameters recorded in the Actigraphy (SE, TST, SA), Insomnia Severity Index (ISI), Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS) and Menopause Quality of Life (Men-QOL). The primary outcomes will be assessed at baseline, week four, week eight, and first and the third month following the end of treatment.
Discussion: If the results confirm that acupuncture is effective and safe for the treatment on insomnia in menopausal women, this positive outcome could provide evidence for clinical application.
Trial Registration: Chinese Clinical Trial Registry, ChiCTR1800018645, Date: 2018-10-01. URL: http://www.chictr.org.cn/showproj.aspx?proj=31482.
Keywords: Menopause; Insomnia; Acupuncture; Clinical trial.
Efficacy of acetaminophen with and without oxycodone for analgesia in nonoperative treatment of extremity fractures in adults: Protocol for a double-blind randomized clinical trial
Authors: Gao Tao , Zhu Hongyi , Zhang Changqing , Chai Yimin , Guo Cheng , Zhu Xiaozhong , Bao Bingbo , Li Xingwei , Lin Junqing , Zheng Xianyou 
Published: February 2019

Abstract
Background: Opioids and acetaminophen are both widely used to relieve pain after nonoperative treatment of limb fractures, but evidence for superiority of opioids versus acetaminophen is lacking. In this study we aim to determine whether acetaminophen is noninferior to the acetaminophen/oxycodone combination for pain relief after nonoperative fixation of an extremity limb fracture. We hypothesize that acetaminophen is noninferior to the acetaminophen/oxycodone combination.
Methods: A double-blind, randomized controlled trial will be conducted. Power analysis determined that 1,226 participants will be needed (p<0.05, power 90%). Patients with acute limb fracture who receive nonoperative treatment will be recruited and randomly allocated into two groups: the intervention group will receive oral oxycodone (5 mg)/acetaminophen (325 mg), and the control group will receive acetaminophen (650 mg) only. The primary outcome measure will be scores on the 11-point Numeric Rating Scale (NRS-11) over 14 days. Secondary outcome measures are scores on the Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), EuroQol five dimensions’ questionnaire (EQ-5d), self-rated satisfaction with the analgesia produced, self-reported nighttime sleep duration, number of intervention or control pills used, total duration for taking intervention or control medication. Change of pain scores and the number of times that analgesic drugs were taken in the two groups will be statistically evaluated with t-student tests according to their fracture site.
Discussion: This study will be a randomized controlled trial that is adequately powered to test the hypothesis that acetaminophen is noninferior to the combination of acetaminophen and oxycodone in relieving objectively measured pain after nonoperative treatment of limb fractures in adults. It is hopeful to provide a safe and effective analgesic plan for such patients.
Trial Registration: ChiCTR registry: ChiCTR1800017015 ( http://www.chictr.org.cn/showproj.aspx?proj=28612). Registered on 8 July 2018.
Keywords: Opioids, acetaminophen, fracture, nonoperative treatment.
Peningkatan Kompetensi Profesional Guru melalui Penelitian Tindakan Kelas
Authors: Annury Muhammad Nafi 
Published: February 2019

<p>This paper evokes efforts to increase teacher competency in the madrasa through classroom action research. In delivering knowledge, not only can it be done in the classroom, but it can also be done outside the classroom. Scientific work is also a professional value of a teacher, because the activity of writing scientific work supports the teaching profession, both in the learning and teaching process or in discussing to solve certain problems proposed. The problems identified in this community service program are: the teachers' knowledge and understanding of Classroom Action Research is still lacking, the teacher's experience in classroom action research is still lacking, the experience of preparing proposals is still lacking, and culture in research activities in the school environment is still lacking. The results obtained through this activity are there is an increase in the understanding of subject teachers in the implementation of Classroom Action Research, an increase in the ability of subject teachers in preparing proposals for Classroom Action Research at SMPIT Assalamah Ungaran and an increase in the ability of subject teachers in conducting Classroom Action Research.</p><p> </p><p>Tulisan ini mengunkap upaya peningkatan kompetensi guru di madrasah melalui penelitian tindakan kelas. Karya tulis ilmiah tidak hanya dapat dinikmati oleh peserta didik, tetapi juga oleh masyarakat luas. Karya ilmiah juga merupakan nilai profesionalisme dari seorang guru, karena kegiatan menulis karya ilmiah mendukung profesi guru, baik dalam proses belajar dan mengajar ataupun dalam berdiskusi untuk memecahkan masalah tertentu yang diajukan. Permasalahan yang diidentifkasi pada program pengabdian kepada masyarakat ini adalah: pengetahuan dan pemahaman para guru tentang Penelitian Tindakan Kelas masih kurang, pengalaman guru dalam hal penelitian tindakan kelas masih kurang, pengalaman menyusun proposal masih kurang, dan budaya dalam hal kegiatan penelitian di lingkungan sekolah masih kurang. Hasil yang diperoleh melalui kegiatan ini yaitu terdapat peningkatan pemahaman para guru mapel disekolah dalam pelaksanaan Penelitian Tindakan Kelas, peningkatan kemampuan para guru mapel dalam menyusun proposal Penelitian Tindakan Kelas di SMPIT Assalamah Ungaran dan terdapat peningkatan kemampuan para guru mapel dalam melaksanakan Penelitian Tindakan Kelas.</p>
Pendampingan Pengembangan Baitulmaal pada Koperasi Syariah Manfaat Surabaya
Authors: Hamdan Ali , Saifuddin Saifuddin 
Published: February 2019

<p>The existence of sharia cooperatives (kopsyah) in Indonesia is relatively new. There are two main pillars of sharia cooperative management, namely social functions (baitulmaal) and business functions (baitut tamwil). The problem that arises in kopsyah in Surabaya is that there is an imbalance in the management of profit-oriented business functions that tend to be dominant compared to their social functions. The factors that caused the weakness of the Baitulmmaal function in Surabaya, the first factor was dominated by management factors, the second factor was more influenced by manpower and environment, while the environmental factors were influenced by the variables the existing muzakki in the kopsyah environment and the unavailability of a juridical basis for kopsyah to manage ZIS funds. Mentoring that the author did on Kopsyah Benefits of Surabaya is conducting training and assistance in the collection and utilization of ZIS and endowments of money to the management staff of Baitulmaal.</p><p> </p><p>Keberadaan koperasi syariah (kopsyah) di Indonesia relatif masih baru. Terdapat dua pilar utama pengelolaan koperasi syariah yaitu fungsi sosial (baitulmaal) dan fungsi bisnis (baitut tamwil). Masalah yang muncul pada kopsyah di Surabaya adalah adanya ketimpangan pengelolaan fungsi bisnis yang berorientasi laba cenderung dominan dibandingkan dengan fungsi sosialnya. Faktor-faktor yang menyebabkan lemahnya fungsi baitulmaal di Surabaya, faktor pertama didominasi oleh faktor manajemen, faktor kedua lebih banyak dipengaruhi oleh manpower (SDM) dan environment (lingkungan), sedangkan faktor lingkungan dipengaruhi oleh variabel tidak dilakukannya penggalangan dana dari para muzakki yang ada dilingkungan kopsyah serta belum tersedianya landasan yuridis bagi kopsyah untuk mengelola dana ZIS. Pendampingan yang penulis lakukan pada Kopsyah Manfaat Surabaya adalah melakukan training dan pendampingan pemghimpunan dan pendayagunaan ZIS dan wakaf uang terhadap SDM pengelola baitulmaal.</p>
KONSTRUKSI AYAT - HADITS EKONOMI DI MEDIA CETAK
Authors: Rahmi Amelia 
Published: February 2019

<p>According to Islam, poverty is a serious problem that should be given serious solution as well. Hence Islam explained the problem of poverty an social inequality in detil, both in the aspect of conception and real solution. The article examines the construction verses and hadiths about economiy contained in Nurul Hayat magazine. By applying semiotic analysis of Roland Barthes to study of Nurul Hayat magazine on February 2015, result show that Nurul Hayat implement Islamic pattern in constructing news and articles. Al-Qur’an verses that are relevant to the theme most of them written with Latin letters and explanation given meaning by Indonesia and simple style of delivery, but for economy hadith, besides written with Arabic letters plus the means. Accurate references, credible source in explaine that theme. Thus, seem that the message was not revealed various meaning, but focusing on the understanding. In addition Nurul Hayat wrote that news and article with prescriptive description, enriched with illustration of famous preacher like Syech Ali Jaber. Charity organized in the dawn of Islam have also been known since the first Java Community with “sedekah laut” and “sedekah bumi”. It was an expression of gratitude to the Almighty God of his success.</p><p>-----------------------------------------------------------------</p><p>Menurut ajaran agama Islam, kemiskinan merupakan problem serius yang harus diberikan perhatian secara serius pula. Karenanya, Islam menjelaskan masalah kemiskinan dan kesenjangan sosial ini secara detail, baik pada aspek konsepsi maupun solusinya. Artikel ini mengkaji tentang konstruksi ayat dan hadits tentang ekonomi yang terdapat dalam Majalah Nurul Hayat. Dari penelitian terhadap majalah Nurul Hayat edisi Februari 2015 dengan menerapkan analisis semiotik model Roland Barthes, diperoleh hasil, majalah Nurul Hayat dalam mengkonstruksi berita maupun artikel mengimplementasikan pola informasi Islami. Ini terlihat dari penggunaan sumber yang jelas, rujukan yang tepat dan gaya penyampaian yang santun. Selain itu dalam menuliskan tema headline dengan pilihan kombinasi antara jenis Banner Headline dengan jenis Spread Headline yang diberi nuansa seni dan ukuran huruf yang mencerminkan sifat tegas/ kuat dan artistik. Ayat suci al Qur’an yang relevan dengan tema kebanyakan ditulis dengan huruf Latin dan diberikan penjelasan makna dalam Bahasa Indonesia, serta gaya penyampaian yang sederhana. Namun untuk hadits ekonomi juga ditulis dalam bentuk tulisan Arab (asli) ditambah terjemahan. Selain itu, berita diperkaya dengan ilustrasi tausiyah dai kodang yang kredibel,dan bersifat preskriptif. Sedekah subuh yang dianjurkan dalam Islam juga telah dikenal masyarakat Jawa secara luas dengan bentuk sedekah laut, sedekah bumi dan sejenisnya, sebagai ungkapan terima kasih kepada Tuhan Yang Esa atas rezeki yag diperoleh.<br /><br /></p><p style="font-size: 14.0pt; font-family: 'Times New Roman','serif'; letter-spacing: -.25pt;"> </p>
PENGEMBANGAN MANAJEMEN PENYIARAN WALISONGO TV
Authors: Hendro W Nur Cahyo 
Published: February 2019

<p><em>Tele</em><em>v</em><em>i</em><em>s</em><em>i</em><em>on is the media most widely consumed by the people of the world and especially Indonesia, with conditions like this the influence of television to be very large on the mindset and patterns of public attitudes. Faculty of Da'wah and Communications UIN Walisongo as an institution that is responsible for the success of Islamic propagation in Indonesia is very appropriate to use television as one of his da'wah media. The management of broadcast television is classified into modern management because all activities in preparing and producing broadcast can not be separated from computer technology. computers have an enormous influence in speeding up a product, with collaboration between software will create new innovation results in broadcast television. The programs that will be presented must be well managed, by conducting scheduling time management of the expected broadcast programs that will be served can be anticipated as early as possible. The production process of television broadcasting must be done before the program is aired. Through the process of film editing in which there is a payload of information a television program can be produced. TV broadcasting program is integrated with Walisongo TV broadcast management information system software.</em></p><p>------------------------------------------------------------------------------------</p><p>Televisi adalah media yang paling luas dikonsumsi oleh masyarakat dunia dan khususnya Indonesia, dengan kondisi seperti ini pengaruh televisi menjadi sangat besar terhadap pola pikir maupun pola sikap masyarakat. Fakultas Dakwah dan Komunikasi UIN Walisongo sebagai sebuah institusi yang ikut bertanggung jawab atas berhasilnya dakwah Islam di Indonesia sangatlah tepat untuk menggunakan televisi sebagai salah satu media dakwahnya. Managemen siaran televisi digolongkan kedalam manajemen modern karena semua aktivitas dalam mempersiapkan dan memproduksi siaran tidak bisa lepas dari teknologi komputer. komputer mempunyai pengaruh yang sangat besar dalam mempercepat menghasilkan sebuah produk, dengan kolaborasi antar software akan tercipta hasil inovasi baru dalam siaran televisi. Program-program yang akan disajikan harus dikelola dengan baik, dengan melakukan managemen penjadwalan waktu siaran diharapkan program-program yang akan ditayangkan dapat diantisipasi sedini mungkin. Proses produksi siaran televisi harus dikerjakan sebelum program tersebut ditayangkan. Melalui proses editing film yang didalamnya terdapat muatan informasi sebuah program tayangan televisi dapat dihasilkan. Program siaran televisi tersebut diintegrasikan dengan software sistem informasi manajemen siaran Walisongo TV.</p>