bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing corporate sustainability via big data analytics, blockchain innovation, and organizational dynamics—A cross‐validated predictive approach
Authors: Xu Youli , Sarfraz Muddassar , Sun Jianmin , Ivascu Larisa , Ozturk Ilknur 
Published: November 2024

AbstractIn today's business landscape, the paramount focus of firms is to achieve advanced corporate sustainability. This objective has led to the development of big data analytics, reliable big and cloud data analytics capabilities, and blockchain technology as powerful tools worldwide that have helped firms increase sustainable performance. Capitalizing on these technologies, this study provides new insight into the role data‐driven competitive sustainability, data‐driven culture, and organizational management information in steering firms' performance. Using a quantitative research approach, data was collected through a structured survey administered to managers and IT professionals across various industries. The relationships between the variables were analyzed using structural equation modeling (SEM), confirming that all proposed hypotheses were supported. The results demonstrate the significant positive impact of big data analytics capabilities, reliable big and cloud data analytics capabilities, and blockchain technology on corporate sustainable performance and data‐driven competitive sustainability. Furthermore, data‐driven competitive sustainability was found to mediate the relationships between BDA, RBCDA, blockchain technology, and corporate sustainable performance. Additionally, OMIS‐fit and data‐driven culture were identified as critical moderators that enhance the effects of these technological capabilities on competitive sustainability and corporate performance. These findings provide valuable insights for organizations seeking to leverage advanced technological capabilities to achieve a sustainable competitive advantage in emerging economies.
Personality traits and circular business models: Fostering consumer engagement with circular economy
Authors: Gomes Sofia 
Published: November 2024

ABSTRACTDespite the growth of the circular economy in the last decade, consumer participation, particularly in circular business models, has still been little explored. Engaging consumers in the circular economy requires not only awareness but also a shift in behavior and mindset toward circularity. Based on the Meta‐Theoretic Model of Motivation and Personality (3 M Model), we explore the role of the big five personality traits as drivers of consumer engagement in a circular economy and their willingness to participate in the circular business model. To this end, we collected a sample of 489 Portuguese consumers, and the Partial Least Square method was applied to the formulated research model. The results demonstrate that personality traits directly affect consumer engagement with the circular economy but not willingness to participate in the circular business model. Engaging with the circular economy in advance is necessary for consumers' personality traits to influence their willingness to participate in the circular business model. Furthermore, this association is stronger if consumers are women and young people. This study contributes to the extension of the 3 M Model to circular consumer behavior and the multidimensionality of the concept of consumer engagement. Furthermore, the results demonstrate that consumers' greater willingness to participate in a circular business model depends on their personality and engagement with the circular economy, allowing companies and policy‐makers to adopt measures to promote the active role of the consumer in the circular economy.
Chondroitin Sulfate‐Coated Heteroduplex‐Molecular Spherical Nucleic Acids
Authors: Laine Toni , Deshpande Prasannakumar , Tähtinen Ville , Coffey Eleanor T. , Virta Pasi 
Published: November 2024

AbstractMolecular Spherical Nucleic Acids (MSNAs) are atomically uniform dendritic nanostructures and potential delivery vehicles for oligonucleotides. The radial formulation combined with covalent conjugation may hide the oligonucleotide content and simultaneously enhance the role of appropriate conjugate groups on the outer sphere. The conjugate halo may be modulated to affect the delivery properties of the MSNAs. In the present study, [60]fullerene‐based molecular spherical nucleic acids, consisting of a 2′‐deoxyribonucleotide and a ribonucleotide sequence, were used as hybridization‐mediated carriers (“DNA and RNA‐carriers”) for an antisense oligonucleotide, suppressing Tau protein, (i. e. Tau‐ASO) and its conjugates with chondroitin sulfate tetrasaccharides (CS) with different sulfation patterns. The impact of the MSNA carriers, CS‐moieties on the conjugates and the CS‐decorations on the MSNAs on cellular uptake and ‐ activity (Tau‐suppression) of the Tau‐ASO was studied with hippocampal neurons in vitro. The formation and stability of these heteroduplex ASO‐MSNAs were evaluated by UV melting profile analysis, polyacrylamide gel electrophoresis (PAGE), dynamic light scattering (DLS) and size exclusion chromatography equipped with a multi angle light scattering detector (SEC‐MALS). The cellular uptake and ‐ activity were studied by confocal microscopy and Western blot analysis, respectively.
Cone‐Rod Dystrophy and Progressive Visual Loss as the First Manifestation of Neuronal Ceroid Lipofuscinosis Type 7: A Case Report
Authors: Hosseini Seyedeh Maryam , Nejad Shahrokh Abadi Reza , Babaei Meisam , Eghbal Fatemeh , Hashemi Narges 
Published: November 2024

ABSTRACTThis case report documents the experience of a 5‐year‐old girl who showed signs of retinal degeneration as the initial symptom of neuronal ceroid lipofuscinosis (NCLs). She originally presented with visual failure, which rapidly progressed to near total bilateral blindness. Two years later, she developed seizures and cognitive impairment, leading to a diagnosis of NCL7 resulting from a homozygote mutation in the MFSD8 gene. This case underscores the importance of considering NCLs as a potential diagnosis in cases of cone‐rod dystrophy and visual loss as the primary clinical feature. It also emphasizes the early onset and initial presentation of retinal degeneration associated with NCL7, before other signs and symptoms manifest, as the second documented case of its kind. Due to the potential for NCL7 to present initially with visual loss before other hallmark signs, it is crucial to consider it among various syndromic and non‐syndromic disorders in the differential diagnosis.
Surgical Repair of a Giant Unruptured Left Sinus of Valsalva Aneurysm in an Older Patient: A Case Report
Authors: Oki Shinichi , Sato Hirotaka 
Published: November 2024

ABSTRACTA giant unruptured left sinus of Valsalva aneurysms is extremely rare. Even if asymptomatic, surgical repair should be performed, considering comorbidities, and patient's physical condition. In this case, patch repair with coronary artery bypass, correction of sinotubular junction, and aortic annulus for aortic regurgitation benefited the older patient.
Conversion of Penta‐Acetyl‐Xylitol to 3‐Acetoxymethylene‐Tetrahydrofuran by a Combined Hetero‐/Homogeneous Tandem Catalyst System
Authors: England Aidan E. , Slater‐Eddy Gabriel Hart , Earnden Laura , van der Zalm Joshua , Schlaf Marcel 
Published: November 2024

AbstractA tandem catalyst system comprised of trifluoromethanesulfonic (triflic acid, HOTf) or hafnium tetratriflate (Hf(OTf)4) and Ru/C in glacial acetic acid (HOAc) as the solvent at 200 °C and ∼ 7 MPa hydrogen pressure in a batch reactor converts penta‐acetyl‐xylitol ((2R,3R,4S)‐pentane‐1,2,3,4,5‐penta‐acetoxy‐pentane) or unprotected xylitol to 3‐acetoxymethylene‐tetrahydrofuran (3‐AMT) in up to 15% yield at full conversion. A comparative analysis by SEM‐EDS and XPS of the fresh commercial Ru/C catalyst versus catalyst reused and recovered after five cycles shows increasing aggregation of ruthenium to larger particles with a concomitant decrease in yield of 3‐AMT to 8%–9% for cycles four and five. 3‐AMT or its hydrolysis product 3‐hydroxymethyl‐tetrahydrofuran (3‐HMT) are valuable synthons for the preparation of agrochemicals, pharmaceuticals, and specialty polyurethanes and polyesters.
Trends in dual antiplatelet therapy regimens and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention with drug‐eluting stents: A multicenter real‐world study
Authors: Wilairat Preyanate , Phrommintikul Arintaya , Chotayaporn Thanyalak , Wattanasombat Supharat , Hmuenpha Rungtiwa , Kornjirakasemsan Supitchaya , Poolpun Duangkamon , Yoodee Voratima 
Published: November 2024

AbstractBackgroundThe patterns of dual antiplatelet therapy (DAPT) use and the associated clinical outcomes in current practice remain limited. This study evaluates DAPT regimen patterns and clinical outcomes among acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI).MethodsThis multicenter retrospective cohort study included ACS patients treated with PCI from January 2017 to February 2022 at five tertiary hospitals in Thailand. DAPT was categorized as nonpotent (NP‐DAPT) or potent (P‐DAPT). We described DAPT trends, with major adverse cardiovascular events (MACEs) and major bleeding, as primary efficacy and safety outcomes. Outcomes were assessed using inverse probability treatment weighting (IPTW) with Cox's proportional hazards model.ResultsThe study included 1877 patients with ACS undergoing PCI. The mean age was 64.51 years (standard deviation 11.34), with 639 (34.04%) female patients and 1159 (61.75%) presenting ST‐elevation myocardial infarction (STEMI). Of these, 924 (49.23%) received NP‐DAPT, and 953 (50.77%) were prescribed P‐DAPT. Crude MACE incidence was lower in the P‐DAPT compared to the NP‐DAPT group (6.82% vs. 10.28%). After applying IPTW and conducting Cox's proportional hazard analysis, no significant differences in MACE were observed between groups (hazard ratio [HR]: 0.85, 95% confidence interval [CI]: 0.58–1.25, p = 0.408), nor in major bleeding (HR: 0.80, 95% CI: 0.37–1.70, p = 0.555). P‐DAPT was associated with any higher bleeding risk (HR: 1.52, 95% CI: 1.13–2.03, p = 0.005).ConclusionStandard DAPT remains predominant among Thai ACS patients, with NP‐DAPT prescriptions approaching those of P‐DAPT. Despite similar rates of MACE and major bleeding between the groups, P‐DAPT was associated with a higher risk of any bleeding.
Analysis and Optimization of Cryogenic Distillation Systems: For Reducing Distillation Energy Consumption
Authors: Qiao Shiwei , Xu Min , Lv Xiaofei , Zhao Huijun 
Published: November 2024

AbstractCarbon capture utilization and storage‐enhanced oil recovery (EOR) is often considered the most promising technology for utilizing CO2. Cryogenic distillation is also viewed as the most reasonable separation option for handling CO2‐EOR gases, despite being an energy‐intensive process. The main challenge for this technology is energy loss. To overcome this challenge, one potential alternative is to optimize the system processes and parameters. This study proposes a new process to reduce distillation energy consumption by refluxing the distillate back to the distillation column. Operational parameter optimization was performed using the commercial simulator Aspen HYSYS for modeling and sensitivity analysis of process parameters using orthogonal experimental methods. The simulation results indicate that after optimization, the energy consumption in the distillation process decreased from 0.207 to 0.196 MJ kg−1, whereas the purity decreased slightly from 94.63 % to 94.52 %. However, the recovery increased from 97.8 % to 97.88 %, and the total energy consumption decreased from 0.772 to 0.761 MJ kg−1.
Self‐supported thin‐film electrode consisting of transition metal borides for highly efficient hydrogen evolution
Authors: Miao Qi , Bao Lihong , Gao Yuxin , Wang Hao , Cao Yongjun , Li Wei , Li Lei , Yang Xiaowei , Zhao Jijun , Ma Ruguang 
Published: November 2024

AbstractTransition metal borides (TMBs) are a new class of promising electrocatalysts for hydrogen generation by water splitting. However, the synthesis of robust all‐in‐one electrodes is challenging for practical applications. Herein, a facile solid‐state boronization strategy is reported to synthesize a series of self‐supported TMBs thin films (TMB‐TFs) with large area and high catalytic activity. Among them, MoB thin film (MoB‐TF) exhibits the highest activity toward electrocatalytic hydrogen evolution reaction (HER), displaying a low overpotential (η10 = 191 and 219 mV at 10 mA cm−2) and a small Tafel slope (60.25 and 61.91 mV dec−1) in 0.5 M H2SO4 and 1.0 M KOH, respectively. Moreover, it outperforms the commercial Pt/C at the high current density region, demonstrating potential applications in industrially electrochemical water splitting. Theoretical study reveals that both surfaces terminated by TM and B atoms can serve as the active sites and the H* binding strength of TMBs is correlated with the p band center of B atoms. This work provides a new pathway for the potential application of TMBs in large‐scale hydrogen production.
Spin‐Electrochemistry of Transition Metal Oxides for Energy Storage: Concepts, Advances and Perspectives
Authors: Yao Shuyun , Zhang Feike , Wang Shiyu , Liu Yuanming , Fu Weijie , Ji Yingjie , Ji Kang , Yang Jinghua , Liu Ruilong , Li Xiaoke , Yang Zhiyu , Yan Yi‐Ming 
Published: November 2024

AbstractDeveloping high‐capacity and cyclically stable transition metal (TM)‐based electrode materials for energy storage devices, such as aqueous ion energy storage systems, is crucial for addressing the growing issue of energy scarcity. The spin state, or spin configuration of the d‐electrons, plays a vital role in the electrochemical energy storage performance of these materials. However, there has been a lack of systematic descriptions regarding the role of spin configurations in electrochemical energy storage to date. This review aims to elucidate the advantages of controlling the spin states of metal centers to enhance energy storage performance and highlights recent progress in employing spin state regulation in electrochemical energy storage. Additionally, it covers the various characterization techniques used to determine spin states. Finally, we discuss the future prospects and challenges within this emerging field, with the aim of accelerating the development of spin‐based electrochemical energy storage technologies. This review also seeks to provide clear and reliable directions for the design and preparation of novel energy storage materials.
Fluorescent Coating through Melanisation of Merocyanine Based on Catechol Chemistry
Authors: Alonso Belén , Samuelsen Lucea Claus , Domini Claudia , Radivoy Gabriel , Mancebo‐Aracil Juan , Nador Fabiana 
Published: November 2024

AbstractIn this study, we present a novel approach for synthesising a merocyanine (MC) compound that integrates gallol and a near‐infrared (NIR) fluorophore using a straightforward method. We conduct a comprehensive structural analysis to elucidate the specific roles of each functional group during monomer synthesis and their effects on the properties of both the spiropyran (SP) and MC forms, particularly their fluorescence. As a proof of concept, we explore the use of these compounds in formulating innovative fluorescent polymeric coatings by melanising catechol and gallol moieties on various substrates, including glass, a cupronickel coin, and an organic polymer. To our knowledge, this is the first report of a bioinspired approach utilizing the melanisation of a catechol and gallol moiety containing merocyanine.
Volatolomics in Fritillarias and Their Identification by Orientation Controlled cMOF Thin Film Chemiresistors
Authors: Cao Lin‐An , Li Yi‐Qian , Huo Yun‐Fei , Sun Lu , Li Xiao‐Qin , Chen Lu , Yang Xue‐Tong , Yuan Fang‐Li , Yao Ming‐Shui 
Published: November 2024

Comprehensive SummaryAs one of the famous traditional Chinese herbal medicines, Fritillariae Cirrhosae Bulbus (FCB) is widely used in the prevention and treatment of respiratory diseases and has the best curative effect among the known fritillarias medicines. Due to the variety, complex sources, similar appearance and shape, it is difficult to distinguish FCB with high curative effect (h‐FCB) from other common fritillarias (c‐FCB) in the market. In this paper, a very simple chemiresistor is used to identify FCB from three commonly used fritillarias drugs. The sensors are fabricated by anisotropic electrically conductive metal‐organic framework (cMOF) thin film Cu3(HHTP)2 (Cu‐HHTP[001] and Cu‐HHTP[100]) as active materials owing to their ability to detect specific groups of volatile organic compounds (volatolomics) as the functional motifs of chemiresistor. As a result, the sensors show orientation‐dependence identification ability to FCB. Cu‐HHTP[001]‐ based sensor shows the highest response (344.17%) to 0.5 g h‐FCB powder volatiles among its three other c‐FCB which is much higher than Cu‐HHTP[100] (135.50%). Ultimately, Cu‐HHTP[001] can realize the identification of FCB with an accuracy of 97.2% in a simple and real‐time manner.
1,2‐Dichloroethane‐Assisted Defluorinative Ring‐Opening Reaction of DABCO and Polyfluoroalkyl Peroxides: Synthesis of Fluorinated N‐Ethyl Piperazines
Authors: Ren Yuan‐Yuan , Ji Wen‐Jun , Zhang Chi , Ge Danhua , Ma Mengtao , Shen Zhi‐Liang , Chu Xue‐Qiang 
Published: November 2024

Comprehensive SummaryA catalyst‐free and additive‐free ring‐opening reaction of polyfluoroalkyl peroxides, triethylenediamine (DABCO), and 1,2‐dichloroethane (DCE) has been developed for the defluorinative synthesis of structurally diverse piperazines featuring a fluoroenone framework and a N‐chloroethyl‐substituent with high Z‐stereoselectivity. The success of this three‐component reaction is attributed to the in situ generation of an active 1‐(2‐chloroethyl)‐1,4‐diazabicyclo[2.2.2]octan‐1‐ium (DABCO·DCE) salt, which judiciously acts as a formal N‐(2‐chloroethyl)piperazine equivalent in the defluorinative coupling with less‐studied aliphatic fluorinated substances. Impressively, this reaction accomplishes multi‐activation of robust C(sp3)‐F, C(sp3)‐Cl, C(sp3)‐O, and C(sp3)‐N bonds in a one‐pot process, offering a practical platform for the late‐stage functionalization of complex molecules. Furthermore, the resulting products can not only serve as versatile building blocks for the synthesis of fluorinated heterocycles, but also undergo C—Cl bond displacement transformations with N‐, O‐, and S‐nucleophiles.
Evaluation of Small Vessel Bifurcation Stenting Using the Double‐Kissing Culotte and Culotte Technique in Acute Coronary Syndrome: 12‐Month Clinical Outcomes
Authors: Barycki Mateusz , Rola Piotr , Włodarczak Adrian , Włodarczak Szymon , Pęcherzewski Maciej , Włodarczak Piotr , Jastrzębski Artur , Furtan Łukasz , Giniewicz Andrzej , Doroszko Adrian , Lesiak Maciej 
Published: November 2024

AbstractIntroductionPatients with small vessels who undergo percutaneous coronary intervention (PCI) with subsequent multiple implantation of drug‐eluting stents remain at a higher risk of unfavorable outcomes. In complex cases where maintaining flow to all side branches is part of contemporary practice, using two‐stent techniques may be appropriate. This study aims to evaluate the efficacy of double‐kissing (DK) culotte technique in comparison to culotte technique in the context of small‐vessel therapy in patients with acute coronary syndrome (ACS).MethodsThis substudy of the Lower Silesia culotte Bifurcation Registry retrospectively analyzed patients who underwent ACS‐PCI using DK culotte or culotte technique for bifurcation lesions in small vessels, defined as having at least one branch with a diameter of 2.75 mm or less. The primary endpoint was target lesion failure (TLF), a composite of cardiovascular death, target vessel myocardial infarction, or clinically driven target lesion revascularization (TLR) at 1‐year follow‐up. The secondary endpoint included major adverse cardiac events (MACE).ResultsThe DK culotte group (n = 49) and the culotte group (n = 52) were compared, with 12‐month follow‐up showing lower TLF in the DK culotte group (8.2% vs. 19.2%, p = 0.082). Similar results were observed for TLR (6.1% vs. 13.5%; p = 0.161), stent restenosis (4.1% vs. 9.6%; p = 0.203), and MACE (18.4% vs. 25%; p = 0.344).ConclusionFor bifurcation lesions with a small‐diameter artery, the DK culotte technique may reduce TLF and MACE compared to the culotte technique. However, given the limited sample size and the absence of statistical significance, these findings remain preliminary and require further investigation.
Towards Precision Biocatalysis – Leveraging Inline NMR for Autonomous Experimentation in Flow Reactors
Authors: Ott Felix , Gygli Gudrun , Rabe Kersten S. , Niemeyer Christof M. 
Published: November 2024

AbstractReactor automation is a transformative force for chemical processes, but the potential of reaction monitoring for machine‐assisted autonomous biocatalytic reaction optimization is still largely unexplored. To address this gap, we report on automated reactor optimization for biocatalytic flow‐through microreactors. For this purpose, the inline NMR analysis of an enzymatically catalyzed stereoselective reduction of a prochiral diketone was combined with a self‐developed open‐source analysis and control software. The algorithm is continuously fed with spectra from a benchtop NMR instrument acquired from a reaction solution from a microreactor filled with biocatalytically active materials and adjusts the flow rate of the pumps to achieve predetermined target concentrations of the product. We show that through this automated coupling of data analysis and process parameterization, for example, maximum conversion efficiency can be achieved for a given bioreactor. This work illustrates the potential of inline NMR reaction monitoring for biocatalytic processes and provides a starting point for innovation to develop automated processes for precision biocatalysis through integrated data analysis.
Macrocyclic Chiral Two‐Dimensional Membranes for Enantiomers Separation
Authors: Feng Yuning , Zhang Haoling , Zhang Chengyu , Fan Yangyang , Yang Lei , Zhang Jian‐Xin , Sun Yue 
Published: November 2024

AbstractChiral enantiomers, while typically exhibiting similar physical and chemical properties, often have distinct therapeutic effects. The preparation of pure enantiomers is therefore of significant interest in the food, chemical, and pharmaceutical industries, making the separation of enantiomers highly sought after. Membrane separation technology has garnered widespread attention for its environmental friendliness and scalability. Recently, chiral two‐dimensional (2D) membranes have demonstrated superior separation performance due to their ultrathin nature and orderly transmission channels. Macrocyclic chiral 2D membranes, in particular, combine the inherent cavity structure of macrocyclic molecules with the host‐guest interaction capabilities that specifically recognize chiral molecules. Additionally, they benefit from the excellent chemical stability and adjustable interlayer spacing of 2D materials. This combination allows these membranes to achieve high enantioselectivity while improving flux. By optimizing the trade‐off between flux and enantioselectivity, this strategy offers a promising new approach for developing advanced chiral membranes.