bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glucose Variables in Type 1 Diabetes Studies With Dapagliflozin: Pooled Analysis of Continuous Glucose Monitoring Data From DEPICT-1 and -2
Authors: Mathieu Chantal , Dandona Paresh , Phillip Moshe , Oron Tal , Lind Marcus , Hansen Lars , Thorén Fredrik , Xu John , Langkilde Anna Maria ,   on behalf of the DEPICT-1 and DEPICT-2 Investigators
Published: April 2019

OBJECTIVE
This pooled analysis assessed continuous glucose monitoring (CGM) in patients with inadequately controlled type 1 diabetes (HbA1c ≥7.7 to ≤11.0% [≥61 to ≤97 mmol/mol]) who received dapagliflozin as an adjunct to adjustable insulin.

RESEARCH DESIGN AND METHODS
CGM data were pooled from two 24-week, double-blind, randomized, phase 3 studies: Dapagliflozin Evaluation in Patients with Inadequately Controlled Type 1 Diabetes (DEPICT-1 and DEPICT-2). These studies comprised 1,591 patients receiving dapagliflozin 5 mg (n = 530), dapagliflozin 10 mg (n = 529), or placebo (n = 532).

RESULTS
Baseline characteristics were balanced between treatment groups. Patients receiving dapagliflozin 5 mg or 10 mg both spent more time with blood glucose in the range &gt;3.9 to ≤10.0 mmol/L (&gt;70 to ≤180 mg/dL) over 24 h than those receiving the placebo. The adjusted mean (SE) change from baseline at week 24 was 6.48% (0.60) with dapagliflozin 5 mg, 8.08% (0.60) with dapagliflozin 10 mg, and −2.59% (0.61) with placebo. At week 24, the mean amplitude of glucose excursion over 24 h, mean 24-h glucose values, and postprandial glucose values were also improved in patients receiving dapagliflozin over those receiving placebo. No marked differences were found at week 24 between dapagliflozin 5 or 10 mg and placebo in the percentage of glucose values ≤3.9 mmol/L (≤70 mg/dL) or ≤3.0 mmol/L (≤54 mg/dL) over 24 h, or in nocturnal (0000–0559 h) glucose values ≤3.9 mmol/L (≤70 mg/dL).

CONCLUSIONS
In patients with type 1 diabetes, treatment with dapagliflozin over 24 weeks improved time in range, mean glucose, and glycemic variability without increasing the time spent in the range indicating hypoglycemia.
Meningkatkan Prestasi Belajar Matematika Melalui Penerapan Model Pembelajaran Saintifik
Authors: Muniasih Ni Ketut 
Published: April 2019

Penelitian tindakan kelas ini bertujuan untuk meningkatkan prestasi belajar Matematika bagi siswa kelas 3 SD No 5 Les pada semester ganjil tahun pelajaran 2018/2019 melalui penerapan Model Pembelajaran Saintifik. Data penelitian dikumpulkan melalui tes prestasi belajar, yang selanjutnya dianalisis dengan menggunakan metode deskriptif kuantitatif. Data disajikan dalam bentuk rata-rata prestasi belajar dan prosesntase ketuntasan belajar. Hasil penelitian ini menunjukkan data awalnya rata-rata hasil belajar siswa hanya 66,32 jumlah siswa yang tuntas sebanyak 13 atau 59,09 %. Pada siklus I setelah dilaksanakan penerapan Model Pembelajaran Saintifik ternyata terjadi kenaikan prestasi belajar yang ditandai dengan rata-rata 69,50 ketuntasan belajar 77,27 %. Dan Setelah memperbaiki kekurangan-kekurangan yang masih terjadi pada siklus I, maka pada siklus II memperoleh data prestasi belajar meningkat menjadi rata-rata 71,68 ketuntasan belajar 90,91 %. Kesimpulan yang diperoleh dari penelitian ini adalah penerapan Model Pembelajaran Saintifik dapat meningkatkan prestasi belajar matematika bagi siswa pada kelas III SD No 5 Les pada smester ganjil tahun pelajaran 2018/2019
“LIFE AFTER PEOPLE”: ZOMBIE APOCALYPSE AND THE STRUCTURES OF THE POST-HUMAN GLOBAL IMAGINARY
Authors: NEAGU Adriana 
Published: April 2019

Life after People: Zombie Apocalypse and the Structures of the Post-Human Global Imaginary. The paper examines post-humanist representations in Anglo-American film productions from a perspective informed by global and hypermodern cultural theory. It is an enquiry into aspects of dystopian sensibility featuring in global cinema, which are seen as manifest in the prolific zombie genre of the post-apocalyptic strand. It is premised on the assumption that global society is endemically marred by a catastrophic horizon of expectation, whose most congenial form of expression is dystopia, a genre on the rise worldwide, especially productive in Anglo-American cinematic practice. Drawing on global cultural theory, I seek to narrow down the enquiry into dystopian modes and bring the zombie dominant to bear on what I construe as the post-apocalyptic imagination of globality.
REZUMAT. Viața după dispariția omului : apocalipsa zombie și structurile imaginarului postuman în era globală. Lucrarea analizează reprezentări postumaniste în producții cinematografice anglo-americane din perspectiva teoriei culturale globale și a hipermodernității. Demersul își propune să trateze aspecte ale sensibilității distopice manifestate în cinematografia globală, aspecte considerate reprezentative pentru filmele zombie din cadrul genului postapocaliptic. Premisa lucrării este dată de teza conform căreia societatea globală este caracterizată de un orizont de așteptare catastrofic, al cărei forme predilecte de expresie este distopia, un gen care înregistrează, în general, o creștere spectaculoasă pe glob și, în special, în cinematografia anglo-americană. Demersul este fundamentat de o grilă teoretică ancorată în teoria globală și vizează fenomenul zombie perceput ca o dominantă a imaginarului postapocaliptic.
Cuvinte cheie: postumanism; distopie; spirit apocaliptic; cinema; dezordine globală; vampir; zombie; teorie globală; hipermodernitate; disjuncție.
By A Law of Motion into The Cause of Gravity
Authors: Van Zanten Leonard 
Published: April 2019

This is an essay written by me when I was yet in my younger years, since then I have simplified the same in several other papers. It intrigues me in my old age now to behold my state of mind in those days long ago.
This essay is a review into the fundamentals of the laws of motion, showing the cause to gravitational force to come about in the same laws by which it is governed. We then may be intrigued to behold how this gravitational force finds its birth by way of “movement into movement upon a twofold inertia". And while it may seem acceptable to us that objects are attracted unto one another proportional to their masses, the evidence in both law and experiment are stacked against it. Hence, the property of mass that gives rise to its force of attraction is found to be “its own movement".
El papel del deporte en las politicas de desarrollo rural de euskadi. Oportunidades, riesgos y una propuesta de investigación evaluativa
Authors: Aldaz Arregu J , Izquierdo Ramírez B 
Published: April 2019

Aunque las investigaciones que combinan deporte y desarrollo rural no son muy profusas a nivel estatal, la preeminencia que ha ido adquiriendo la práctica deportiva, y su vinculación con las zonas rurales como espacio de «uso» lo convierten en objeto de estudio novedoso y muy interesante desde la perspectiva de la gestión de políticas públicas. En efecto, la deportividad de la sociedad se ha convertido en objeto de estudio emergente en el ámbito sociológico derivado su elevado impacto socioeconómico y las motivaciones que subyacen a dicha práctica entre otros aspectos principales. Al mismo tiempo, las zonas rurales, promovidas por una intensa política de desarrollo rural, asisten a su transformación en escenario privilegiado para la práctica deportiva, aumentando de manera significativa el desarrollo de actividades deportivas que utilizan estos espacios.
Abstracts del I Congreso Internacional en Ciencias del Ejercicio y la Actividad Física. San José de Costa Rica. Agosto de 2017
Authors: Bonilla DA 
Published: April 2019

Suplementos nutricionales para el aumento de la masa muscular y la pérdida de grasa. Bonilla, DA; Pérez-Idárraga, A; Marín, E; Kammerer, M; Petro, JL.Entrenamiento de la fuerza. Aspectos fisiológicos y metodológicos. Petro, JL; Bonilla DA; Marín, E; Vargas, S.Nutrición en fitness y deportes de fuerza. Solís-Agüero, MLNutrición para deportes de larga duración. Gómez-Martín, LADetección de posibles talentos deportivos, en el entorno escolar. Alexander-Cortez, PAEstrategias de trabajo para la reducción del tejido adiposo. Vargas, S; Petro, JL; Bonilla DA; Carbone, L
Impact of fertility variation on genetic diversity and phenotypic traits in second generation seed production areas and clonal seed orchards of Eucalyptus camaldulensis
Authors: Suraj P.G. , Nagabhushana K. , Kamalakannan R. , Varghese M. 
Published: April 2019

Abstract
Fertility and gene diversity were estimated in three second generation (F
2
) seed stands (SPA 1-3) and two clone trials (CSO 1&2) of Eucalyptus camaldulensis to assess the impact on seed crop. F
2
seedlots were evaluated in comparison to native provenances, ten commercial clones and interspecific hybrids at diverse sites. SPA 1&2 were genetic gain trials of five first generation (F
1
) orchard seedlots, SPA 3 a plantation of one F
1
orchard seedlot, and CSOs were clone trials of 21 commercial clones established at two contrasting sites. Fertility variation, as indicated by sibling coefficient, was high (Ψ, 9-14) in the SPAs as only about 26 % trees were fertile compared to 81 % trees in CSOs. Effective population size was higher in SPA 1 and 2 (N

s
, 95 and 74, respectively) than SPA 3 (N

s
= 39). Fertility was highly skewed in CSO 2 resulting in low effective population size (N

s
= 2) compared to CSO 1 (N

s
= 11). Constant seed collection enabled 3-fold increase in relative population size and 22 % higher predicted gene diversity in CSO 2. Genetic diversity (H

e
) estimated using SSR markers was higher in SPA 1&2 and native provenances (NAT), compared to SPA 3 and CSO 1, whereas CSO 2 and clones had lower values. There was a high positive correlation between estimated H

e
and predicted gene diversity values of SPAs and CSOs. H

e
was positively correlated to mean field survival and negatively correlated to kraft pulp yield (KPY), evaluated at three years in progeny trials across three locations. Number of alleles per locus was higher in SPAs and native provenances compared to CSOs and clones. Discriminant principal component analysis clustered CSO, NAT and SPA seedlots in different groups while commercial E. camaldulensis clones clustered close to NAT. Multilocus outcrossing rate was generally high (t

m
, 91-100 %), though selfing was observed in two families of SPA 3 and CSO 2. Selected interspecific hybrid families of commercial E. camaldulensis clones (with E. urophylla and E. pellita) evaluated at two of the sites had higher H

e
and KPY than clones at three years.
Das Lebensende in der Schweiz - Individuelle und gesellschaftliche Perspektiven
Authors: Zimmermann Markus , Felder Stefan , Streckeisen Ursula , Tag Brigitte 
Published: April 2019

Dieses Buch bietet einen verständlich formulierten Überblick über das, was heute zum Lebensende in der Schweiz aus wissenschaftlicher Sicht bekannt ist. Die geburtenstarken Jahrgänge – die sogenannten Babyboomer – werden bald ins hohe Alter kommen. Dadurch wird sich der politische Druck erhöhen, die Versorgung der Menschen am Lebensende in der Schweiz besser zu planen. Entscheidungen stehen sowohl auf individueller organisatorischer als auch auf gesamtgesellschaftlicher Ebene an. Behandelt werden Kernthemen wie individuelle Erfahrungen, Entscheidungen über das eigene Lebensende, Versorgungssituation, Kosten, rechtliche Regelungen sowie Sterbeideale. Die Autorinnen und Autoren vertreten unterschiedliche wissenschaftliche Disziplinen und sind Mitglieder der Leitungsgruppe des Nationalen Forschungsprogramms NFP 67 «Lebensende».
La Fin de vie en Suisse - Perspectives individuelles et sociales
Authors: Zimmermann Markus , Felder Stefan , Streckeisen Ursula , Tag Brigitte 
Published: April 2019

Dans un langage accessible, ce livre propose un aperçu de ce que l’on sait actuellement sur la fin de vie en Suisse du point de vue scientifique. Les personnes nées dans les années de forte natalité (génération du baby-boom) atteindront bientôt un âge avancé. Il faut donc s’attendre à ce que se multiplient les voix demandant à la politique de mieux planifier la prise en charge des personnes en fin de vie en Suisse. Des décisions devront être prises, tant à l’échelon individuel qu’organisationnel ou qu’à celui de la société dans son ensemble. Les problématiques fondamentales suivantes sont abordées : expériences individuelles, décisions personnelles au sujet de la fin de vie, conditions de prise en charge, coûts, règlementations juridiques et idéaux du « bien mourir ». Les auteures et auteurs représentent différentes disciplines scientifiques et sont membres du Comité de direction du Programme national de recherche PNR 67 « Fin de vie ».
The Implementation of Tri Hita Karana on the World Heritage of Taman Ayun and Tirta Empul Temples as Tourist Attractions in Bali
Authors: Ardika I Wayan 
Published: April 2019

Cultural Landscape of Bali Province has been determined by Unesco as World Heritage List in 29 June 2012. The outstanding universal value of the Cultural Landscape of Bali Province is based on Tri Hita Karana which is basically deal with harmony and balance between religous, social, and environment. The Cultural Landscape of Bali Province consists of several temples in association with subak include: Ulun Danu Batur temple, Tirta Empul temple and several archaeological sites along the Pakerisan river, Taman Ayun temple, and subak of Catur Angga of Batukaru temple. Ulun Danu Batur, Tirta Empul, and Taman Ayun temples are considered as the sources of water for several subaks in the Southern Bali. This paper will describe the implementation of Tri Hita Karana philosopy in relation to the temple of Taman Ayun and Tirta Empul as parts of World Heritage list and tourist attractions in Bali. It should be noted that Tri Hita Karana philosopy is also the basis of cultural tourism program in Bali. In other words, the outstanding universal value of the Cultural Landscape of Bali Province is in line with cultural tourism program which is based on Tri Hita Karana. The philosopy of Tri Hita Karana has been implemented at Taman Ayun and Tirta Empul temples as tourist attractions in Bali. However, touristification or commodification has occurred in relation to religious aspects. For instance, tourists are allowed to enter the temple at Taman Ayun without wearing Balinese costumes, and tourists are permitted to enter the the most sacred yard or jeroan at Tirta Empul although restriction for tourists is implemented. Social aspects of Tri Hita Karana have been neglected at Taman Ayun and Tirta Empul. Information concerning the functions of shrines (palinggih), ceremonies, history as well as local guides are not available at both temples. The environment surrounding of both temples have been managed properly, however toilets and rubbish bins need to be improved and put on the right places at Tirta Empul. The philosopy of Tri Hita Karana need to be implemented properly in order to gain harmony and balance between religious, social, and environment on the World Heritage sites of Taman Ayun and Tirta Empul temples as tourist attractions in Bali.
Developing Dayah as Religious Tourism Destination in Aceh
Authors: Heriani Heriani , Baiquni M , Wijono Djoko , Widyaningsih Yulia Arisnani 
Published: April 2019

Aceh has several religious tourism destinations, especially the historic mosques and the graves of the Ulama but it turns out that many tourists also come and visit Dayah. The flow of tourist arrivals to Dayah has not been well organized, whereas the potential of Dayah as a religious tourism destination is very large to be developed. This study aims to provide an overview of the potential and strategy of Dayah development as one of the religious tourism destinations in Aceh. The research method used in this research is qualitative with observation and interview based on primary and secondary data. The results show that some Dayah in Aceh who have great potential need to be developed as a religious tourism destination. The potential development efforts can be through several strategies that involve the role of government, Ulama and Dayah managers and the Dayah community.
Keywords: Dayah, potential, strategy, religious, tourism
The Multiplier Effect of Buying Local Gastronomy: Case of Sundanesse Restaurant
Authors: Turgarini Dewi , Baiquni Muhammad , Harmayani E. 
Published: April 2019

Bandung is one of the cities in Indonesia which has a gastronomic diversity represents Sundanese culture as its original inhabitants. This capital city of West Java province has a lot of culture, history, and archeologyicons that are nuanced Sunda, and Colonial. Therefore, the city can be said as the city of heritage landmark (heritage-city), and gastronomical attractions can be integrated as Gastro-city. Currently the local food of Sundanese has many variants but the level of attractiveness of the food is still considered insufficient. Research was designed to find a decent meal variant proposed as a superior food; and find out what food variants as the main attraction of the city as well as to assess multiplier effect of buying local gastronomy. Both are expected to answer a question of what is base for the economic development of Bandung as Gastro city. It is also interesting to find out the multiplier effect of buying local gastronomy especially in Sundanese restaurant. The method used is descriptive exploratory study, also conducted professional assessment. Data collecting technique were observation, interviews, and examination of documents. Data was analysed using descriptive exploratory approach. The results showed that the Sundanese have a tourist attraction with the potential of the existence of 74 species featured menu consisting of appertizer, maincourse, dessert and drink as trademark. The food appeared in 24 ceremonies as a vibrant cultural event in the life cycle of Sunda tribe who live in the city of Bandung. The tourists also can enjoy a diverse featured menu in the 145 Sundanese restaurant in Bandung city. The value of the multiplier effect of tourist expenditure during the year amounting to 1,286 times that of the developing tourist spending.
Keywords: Gastronomy, Sundanese, Restaurant, Multiplier Effect, Tourist Attractions
The Effect of the Quality of Services on the Visitors’ Satisfaction and Desire to Pay a Revisit to the Bali Pulina Agrotourism
Authors: Purnami Ni Nyoman Alit , Oka Suryawardani I Gusti Ayu 
Published: April 2019

The perception of the visitors of the quality of the services provided at the Bali Pulina Agrotourism contributed to their satisfaction, which would then make them desirous of paying a revisit to it. The research was conducted at the Bali Pulina Agrotourism. This study was intended to analyze the effect of the quality of services (physical evidence, reliability, responsiveness, assurance, and empathy) on the visitors? satisfaction with the Bali Pulina Agrotourism, and analyze the effect of the visitors? satisfaction on their desire to pay a revisit to it. The respondents in this study were the tourists who had visited the Bali Pulina agrotourism, totaling 80 and obtained using the accidental sampling method. The model was designed based on the Smart PLS version 3.0-based Structural Equation Modelling (SEM) using a computer program. The results of the study showed that physical evidence significantly contributed to the visitors? satisfaction (p = 0.002); reliability significantly contributed to the visitors? satisfaction (p = 0.005); responsiveness significantly contributed to the visitors? satisfaction (p = 0.040); assurance significantly affected the visitors? satisfaction (p = 0.001); empathy significantly affected the visitors? satisfaction (p = 0.014); the visitors? satisfaction significantly contributed to their desire to pay a revisit to the Bali Pulina Agrotourism (p = 0,000). Based on the results of the study, the Bali Pulina Agrotourism was expected to be able to maintain and improve the quality of services to make the visitors feel satisfied and desirous of paying a revisit.
Keywords: agrotourism, service quality, satisfaction, revisit, PLS
Does Motivation and Trust Important for Tourists’ Loyalties? A Quantitative Perspective from Golf Tourism in Bali of Indonesia
Authors: Kuhn Panudiana , Bendesa Komang Gde , Wiranatha Agung Suryawan 
Published: April 2019

Golf is one of several sport tourist attractions that are increasingly demanding by domestic and foreign tourists during their visit to Bali. Unlike the others type of tourist attractions, golf tourism could be classified as a quality attraction. Tourists who play golf spend more money than other sport activities. Refers to this fact, golf tourism could be an alternative to realizing the establishment of quality tourism in Bali. This work aims to study the significance of the determinants of tourists' satisfaction as well as their loyalty in visiting Bali as a destination that offers golf attractions. Intrinsic motivation and extrinsic motivation from golfers are positioned as the antecedent of the level of satisfaction with their trust to the golf providers acts as the mediation of the causal relationship occured. Using 5-scale Likert questionnaire, the opinions of 113 foreign tourists who played golf in Bali were used to examine the structural equation models that were built. The results of the analysis show that both types of motivation have positive influences on tourist trust in golf operators, and through the trust mediation, these motivations positively influence the level of tourist loyalties. The results of the analysis also showed that tourists’ trust to the golf operators had a significant effect on tourist loyalty. The main findings of this research conclude the vital role of tourists’ trust to the golf operators in Bali in increasing their loyalty to play golf while visiting Bali.
Keywords : golf, trust, satisfaction, loyalties, motivation, SEM.
Relationship between Marketing Mix and Cunsomers’ Loyalty of Hatten Wines Products
Authors: Citra Dewi Ida Ayu Putu , Suryawardani I Gusti Ayu Oka 
Published: April 2019

Hatten Wines is one of the alcoholic beverage products produced in Bali and owned by Balinese. Its role is very important as a substitute product for imported alcoholic beverage products. The research objectives are: (i) identifying the marketing mix variables that determine the purchasing decisions and loyalty to Hatten Wines products and their forming indicators, and (ii) investigating the roles of marketing mix on the customers' purchasing decisions and loyalty to Hatten Wines products. The study was conducted in Sanur, Kuta and Nusa Dua by distributing questionnaires to 100 foreign tourists. The data was analyzed based on the factor analysis by using SPSS program. The results of the study indicate that; (i) Marketing Mix variables that determine the purchasing decisions and product loyalty to Hatten Wines consist of products, prices, promotions, places and distribution. Product variables are formed from five indicators, namely brand, taste, packaging, aroma, and product variety. Price variables are formed from three indicators, namely affordability of prices, value for money, and price competitiveness. Promotion variables are formed from four indicators, namely promotion services, media promotion, promotion quality, and promotion quantity. Place and distribution variables are formed from three indicators, namely place of sale, product availability, and ease of access. (ii) Hatten Wines Marketing Mix plays a positive role and is significantly related to the consumers' purchasing decisions and loyalty in consuming Hatten Wines, which is 60.946%. The remaining 39.054% is influenced by other variables not included in the model.
Keywords: marketing mix, consumers’ loyalty, Hatten Wines, Bali.