bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematic literature review of themes and definitions of industrialized construction
Authors: Kauppinen Laura , Annunen Petteri , Haapasalo Harri 
Published: November 2024

PurposeIndustrialized construction has brought about expectations of improved productivity in the construction industry. However, the lack of a commonly accepted definition has created confusion regarding the types of development covered by the industrialized construction umbrella. These inconsistent definitions convoluted the discussion on this phenomenon. This study aims to clarify the definition of industrialized construction through a systematic literature review.Design/methodology/approachThis systematic literature review was conducted according to PRISMA principles. Records were gathered from Scopus and Web of Science. Following the scientometric analysis, content analysis was conducted according to the template analysis approach.FindingsThe analysis of 121 articles revealed four main themes related to industrialized construction: 1) the construction concept, 2) construction methodologies, 3) systematization, rationalization and automatization and 4) societal and industrial change processes. Definitions of industrialized construction can be analyzed with seven clusters: 1) prefabrication, 2) standardization, 3) sector, 4) integration, 5) manufacturing practices, 6) technological investment and 7) none. Based on the content analysis, the proposed definition is: industrialized construction is the adoption of practices that minimize project-specific work in construction from the start of the design to the end of the building’s life cycle.Originality/valueThis study proposes a definition for industrialized construction following content analysis of broadly sampled literature. The proposed definition can provide a basis on which developments in the construction industry can be reflected.
Traveling with ChatGPT and providing translation services for travelers
Authors: Kundan Zheng , Hossain Md Sazzad , Shahidul Islam Mohammad , Alam Mohammad Nurul , Parvez M. Omar 
Published: November 2024

Purpose
Language barriers have always been obstacles to traveling abroad, making travelers less interested. This study aims to investigate how ChatGPT, as a translator, affects travelers’ behavioral intentions based on the perceived language barriers using the ChatGPT voice translation app.

Design/methodology/approach
A total of 531 responses were collected over a specific survey period using a cross-sectional time frame. This study proposed a research model based on technology acceptance model (TAM) and unified theory of acceptance and use of technology (UTAUT), and the proposed hypotheses were investigated using bootstrapping techniques and Smart-PLS analysis.

Findings
This study’s results are significant as they reveal that ChatGPT enables translated service to travelers and enhances their willingness to travel abroad. This finding indicates a considerable enhancement in the traveler’s confidence in communicating with residents, thereby emphasizing ChatGPT’s pivotal role in overcoming language barriers in the travel industry.

Originality/value
This research is novel in its approach as it delineates the influence of ChatGPT’s translation services on travelers’ willingness and behavioral intentions regarding international travel. By filling a significant gap in the existing literature, this study provides a fresh perspective on the role of technology in overcoming language barriers in the travel industry.
Development of a tailored questionnaire instrument to evaluate thermal sensation of elderly people in India
Authors: Sudarsanam Niveditha , Kannamma D. 
Published: November 2024

Purpose
India’s growing elderly population necessitates ensuring indoor thermal comfort because of their vulnerability to temperature-related illnesses and reduced capacity to regulate body temperature. Currently, thermal sensation (TS) assessment scales, designed for those between 20 and 60 years of age, may not accurately capture the preferences of elderly adults. To address the gap, this study aims to identify appropriate scaling methods to help the elderly understand the American Society of Heating, Refrigerating and Air-Conditioning Engineers (ASHRAE-55) seven-point TS scale clearly.

Design/methodology/approach
Four scaling methods – color, emoji, landscape images and regional images scales – identified from literature were analyzed using quantitative approaches. The differences between two age groups (<60 years and = 60 years) were examined using frequency distribution differences and independent sample t-test methods.

Findings
Results indicated that both younger/middle-aged (<60 years) and elderly individuals (= 60 years) were adept at identifying color and regional images scale, while emoji and landscape images scale posed challenges for the elderly. Furthermore, a tailored questionnaire instrument was developed to enhance the comprehension of TS questions for the elderly. One sample t-test results indicated that the proposed questionnaire instrument is a better fit to support ASHRAE-55 seven-point TS scale, making it particularly effective for the elderly population.

Originality/value
This research presents a novel, tailored questionnaire instrument that significantly enhances the elderly population’s comprehension of TS questions, thereby improving the accuracy of thermal comfort assessments and contributing to the creation of better indoor thermal environments for the elderly people.
Tissue‐specific alternative splicing and the functional differentiation of LmLPMO15‐1 in Locusta migratoria
Authors: Kong Lin , Hu Huiying , Li Pengfei , Qu Mingbo 
Published: November 2024

AbstractInsect lytic polysaccharide monooxygenases (LPMO15s) are newly discovered copper‐dependent enzymes that promote chitin degradation in insect through oxidative cleavage of glycosidic bonds. They are potential pesticide targets due to their critical role for chitin turnover in the integument, trachea, and peritrophic matrix of the midgut during insect molting. However, the knowledge about whether and how LPMO15s participate in chitin turnover in other tissues is still insufficient. Here, using the orthopteran pest Locusta migratoria as a model, a novel alternative splicing site of LmLPMO15‐1 was discovered and it produces 2 variants, LmLPMO15‐1a and LmLPMO15‐1b. The transcripts of LmLPMO15‐1a and LmLPMO15‐1b were specifically expressed in the trachea and foregut, respectively. RNA interference targeting LmLPMO15‐1 (a common fragment shared by both LmLPMO15‐1a and LmLPMO15‐1b), a specific region of LmLPMO15‐1a or LmLPMO15‐1b all significantly reduced survival rate of nymphs and induced lethal phenotypes with developmental stasis or molt failure. Ultrastructure analysis demonstrated that LmLPMO15‐1b was specifically involved in foregut old cuticle degradation, while LmLPMO15‐1a was exclusively responsible for the degradation of the tracheal old cuticle. This study revealed LmLPMO15‐1 achieved tissue‐specific functional differentiation through alternative splicing, and proved the significance of the spliced variants during insect growth and development. It provides new strategies for pest control targeting LPMO15‐1.
Trends of genetic contributions on epigenetic clocks and related methylation sites with aging: A population‐based adult twin study
Authors: Hong Xuanming , Cao Hui , Cao Weihua , Lv Jun , Yu Canqing , Huang Tao , Sun Dianjianyi , Liao Chunxiao , Pang Yuanjie , Hu Runhua , Gao Ruqin , Yu Min , Zhou Jinyi , Wu Xianping , Liu Yu , Yin Shengli , Gao Wenjing , Li Liming 
Published: November 2024

AbstractSeveral crucial acceleration periods exist during aging process. Epigenetic clocks, serving as indicators of aging, are influenced by genetic factors. Investigating how the genetic contributions on these clocks change with age may provide novel insights into the aging process. In this study, based on 1084 adult twins from the Chinese National Twin Registry (CNTR), we established structural equation models (SEMs) to evaluate the trends in genetic influence with aging for epigenetic clocks, which include PC‐Horvath, PC‐Hannum, PC‐PhenoAge, PC‐GrimAge, and DunedinPACE. A decline in overall heritability was observed for all five clocks from ages 31 to 70, with a relatively stable trend at first. Subsequently, apart from PC‐GrimAge, the other four clocks displayed a more evident drop in heritability: DunedinPACE and PC‐PhenoAge experienced a clear decline between 55 and 65 years, while PC‐Horvath and PC‐Hannum showed a similar decrease between 60 and 70 years. In contrast, the heritability of PC‐GrimAge remained stable throughout. An analysis of methylation sites (CpGs) from these clocks identified 41, 26, 4, and 36 CpG sites potentially underlying heritability changes in DunedinPACE, PC‐Horvath, PC‐Hannum, and PC‐PhenoAge, respectively. Data from the CNTR were collected through two surveys in 2013 and 2018. Based on 308 twins with longitudinal data, declines in genetic components were observed at follow‐up compared to baseline, with significant decreases in the four PC‐clocks. DunedinPACE peaked in 5‐year longitudinal genetic contribution changes at age 55–60, while PC‐clocks consistently peaked at age 50–55. These findings may offer novel insights into the role of genetic variations in aging.
Anxiety and depression among a community‐recruited cohort of people who use methamphetamine: A longitudinal analysis
Authors: Duncan Zoe , Kippen Rebecca , Sutton Keith , Ward Bernadette , Rathnayake Kasun , Quinn Brendan , Dietze Paul 
Published: November 2024

AbstractAimsThis study (1) estimated changes in anxiety and depression throughout 3 years in a community‐recruited cohort who use methamphetamine and (2) modelled whether these changes were associated with patterns of methamphetamine use or other time‐varying or fixed covariates.Design, setting and participantsWe used a longitudinal analysis using data derived from surveys conducted between August 2016 and March 2020, set in metropolitan and rural locations in Victoria, Australia. Participants comprised a total of 849 adults with regular methamphetamine use history at baseline, recruited for the prospective VMAX study via snowball and respondent‐driven sampling.MeasurementsAnxiety and depression symptoms were measured using the Generalized Anxiety Disorder (GAD)‐7 and the Patient Health Questionnaire (PHQ)‐9 instruments. Frequency of methamphetamine use was measured by self‐reported number of days per week participants used any form of methamphetamine in the past month.FindingsChanges in anxiety and depression symptom scores were associated with change in route of administration from non‐injecting to injecting [adjusted coefficient (adj. coeff.) = 1.44, 95% confidence intervals (CI) = 0.39, 2.48, adj. coeff. = 1.49, 95% CI = 0.39, 2.58], change in severity of dependence for methamphetamine (adj. coeff. = 0.29, 95% CI = 0.21, 0.37, adj. coeff. = 0.34, 95% CI = 0.26, 0.42), starting treatment for drugs other than methamphetamine (adj. coeff. = −2.21, 95% CI = −3.70, −0.73, adj. coeff. = −2.09, 95% CI = −3.60, −0.58) and other covariates.ConclusionsAmong regular methamphetamine users in Australia, changes in anxiety or depression scores are associated with changes in route of administration, dependence severity and starting treatment for other drugs, but do not appear to be associated with frequency of methamphetamine use.
Hypothermia—Prevalence and risk factors in neonates admitted to a neonatal unit in Tanzania
Authors: Braa Hanne Gaup , Mathisen Elisabeth Asta , Moshiro Robert , Daudi Vickfarajaeli X. , Francis Fortunata , Mduma Esto , Ersdal Hege , Størdal Ketil 
Published: November 2024

AbstractAimWe aimed to study the prevalence of hypothermia among neonates, the association between admission temperature and neonatal mortality, and the impact of radiant warmers.MethodsIn an observational prospective study, we included 1988 neonates born at Haydom Lutheran Hospital, Tanzania, and admitted to the neonatal unit from 1 January 2018 to 31 December 2022. We explored risk factors for hypothermia (<36.0°C, primary outcome) and newborn mortality by admission temperature (secondary outcome) with adjusted odds ratios (aOR) and 95% confidence intervals (CI) for birth weight and bag and mask ventilation.ResultsHypothermia was present in 47.0% (n = 935) at admission, 46.9% (n = 932) were normothermic or mildly hypothermic (36.0–37.5°C), and 6.1% (n = 121) hyperthermic. Of those admitted to the neonatal unit, 217 (10.9%) died. For every 1°C increase in temperature, neonatal mortality decreased by 31% (aOR 0.69, 95% CI 0.59–0.82). Admission temperature <34.5°C was strongly associated with mortality (aOR 3.56, 1.87–6.79). Mild hypothermia (36.0–36.5°C) was not associated with mortality (aOR 1.30, 0.72–2.37). Risk factors for hypothermia were bag and mask ventilation (aOR 2.53, 2.07–3.11) and low birth weight. The introduction of radiant warmers from 1 May 2022 was associated with a decrease in hypothermia (aOR 0.54, 0.41–0.72).ConclusionHypothermia is prevalent even in tropical settings and maintaining normothermia after birth is critical and achievable for reducing neonatal mortality.
Amount, type and storage of medicines in households – A survey for medicine users
Authors: Louhisalmi Mella , Lavikainen Piia , Linden Kari , Martikainen Janne , Timonen Johanna 
Published: November 2024

AbstractWith increasing medicine use, more medicines are being stored at home, yet the understanding of household medicines remains limited. This study aimed to assess the amount, type and storage practices of medicines in households. It also explored the reasons for unnecessary or expired medicines, as well as the factors associated with the presence of expired medicines in a household. The online survey was conducted among loyal customers of University Pharmacy in June 2023 (n = 5004). The data were analysed for frequencies and percentages, and binary logistic regression was used to examine the association between background factors and expired medicines in households. On average, one household had 13.9 active, 2.8 unnecessary and 2.2 expired medicine packs. Medicines were typically stored in the kitchen (67.0%) and in cabinets (58.7%), and 40% were to be stored safely. The main reasons for unnecessary or expired medicines were improved health (39.2%), medication changes (31.9%) and oversized packs (28.0%). Households returning medicines biennially (odds ratio (OR): 2.85; 95% confidence interval (CI): 2.13–3.82) and those with many active medicines (OR: 2.14; 95% CI: 1.79–2.54) had expired medicines more often. The study showed that households had many medicines, highlighting the need for better storage and optimized packaging to improve safety, reduce waste and enhance rational pharmacotherapy.
Clonal haemopoiesis and venous thromboembolism risk
Authors: Steensma David P. 
Published: November 2024

Many cases of venous thromboembolism (VTE) are idiopathic and clonal haemopoiesis, a risk factor for atherosclerotic vascular disease, may be a contributing factor to VTE. The report by Englisch and colleagues suggests that clonal haemopoiesis is a risk factor for recurrent VTE, especially in people without identifiable thrombotic predisposition.Commentary on: Englisch et al. Association of clonal hematopoiesis with recurrent venous thromboembolism: A case‐control study. Br J Haematol 2025; 206:263‐271.
Zooming in the plastisphere: the ecological interface for phytoplankton–plastic interactions in aquatic ecosystems
Authors: Nava Veronica , Dar Jaffer Y. , De Santis Vanessa , Fehlinger Lena , Pasqualini Julia , Adekolurejo Oloyede A. , Burri Bryan , Cabrerizo Marco J. , Chonova Teofana , Cour Mathilde , Dory Flavia , Drost Annemieke M. , Figler Aida , Gionchetta Giulia , Halabowski Dariusz , Harvey Daniel R. , Manzanares‐Vázquez Víctor , Misteli Benjamin , Mori‐Bazzano Laureen , Moser Valentin , Rotta Federica , Schmid‐Paech Bianca , Touchet Camille M. , Gostyńska Julia 
Published: November 2024

ABSTRACTPhytoplankton is an essential resource in aquatic ecosystems, situated at the base of aquatic food webs. Plastic pollution can impact these organisms, potentially affecting the functioning of aquatic ecosystems. The interaction between plastics and phytoplankton is multifaceted: while microplastics can exert toxic effects on phytoplankton, plastics can also act as a substrate for colonisation. By reviewing the existing literature, this study aims to address pivotal questions concerning the intricate interplay among plastics and phytoplankton/phytobenthos and analyse impacts on fundamental ecosystem processes (e.g. primary production, nutrient cycling). This investigation spans both marine and freshwater ecosystems, examining diverse organisational levels from subcellular processes to entire ecosystems. The diverse chemical composition of plastics, along with their variable properties and role in forming the “plastisphere”, underscores the complexity of their influences on aquatic environments. Morphological changes, alterations in metabolic processes, defence and stress responses, including homoaggregation and extracellular polysaccharide biosynthesis, represent adaptive strategies employed by phytoplankton to cope with plastic‐induced stress. Plastics also serve as potential habitats for harmful algae and invasive species, thereby influencing biodiversity and environmental conditions. Processes affected by phytoplankton–plastic interaction can have cascading effects throughout the aquatic food web via altered bottom‐up and top‐down processes. This review emphasises that our understanding of how these multiple interactions compare in impact on natural processes is far from complete, and uncertainty persists regarding whether they drive significant alterations in ecological variables. A lack of comprehensive investigation poses a risk of overlooking fundamental aspects in addressing the environmental challenges associated with widespread plastic pollution.
Early Detection of Psychosis in Eating Disorders: Unnecessary or a Useful Addition?
Authors: de Bont Paul A. J. M. , Seelen‐de Lang Birgit , Maas Joyce , Bodde Nynke M. G. 
Published: November 2024

ABSTRACTAimThe absence of consensus regarding the presence and interpretation of certain symptoms as indicative of either a psychosis spectrum disorder or an eating disorder (ED) can hinder cooperation amongst treatment programmes for the early detection of psychosis and an ED. This study trans‐diagnostically assessed the prevalence and co‐occurrence of at‐risk mental states for a psychosis (ARMS) or the risk of having an ED (EDr), and it explored the characteristics of ARMS profiles of individuals with an EDr.MethodThis cross‐sectional and observational‐prevalence study used assessment outcomes from an ED screening instrument (SCOFF), a psychosis prodromal screening questionnaire (PQ16) and a CAARMS interview (to evaluate the possibility of ARMS) with newly admitted outpatients aged 16–35 who were referred for various kinds of non‐psychotic disorders from a secondary Mental Health Care Centre in the Netherlands. Data analysis consisted of calculating prevalences, associations amongst variables and conditional probabilities.ResultsOf the 736 individuals who were screened, an EDr was identified in 51.2% and 49.0% of the participants who scored high on the PQ16, half of whom also completed the CAARMS interview. The results indicated that 53.0% of the participants were classified as not having ARMS, 28.3% as having ARMS and 18.7% as having a psychosis. EDr patients presented with symptoms of a psychotic spectrum disorder, which included both ED‐consistent and ED‐inconsistent symptoms. There were relatively frequent endorsements of the two subscale items guilt/punishment and ideas of reference.ConclusionsFrom a trans‐diagnostical perspective, the results indicate that collaboration amongst ED programmes and psychosis prevention interventions should be strongly encouraged. Future researchers are encouraged to conduct studies that assess associations amongst and features of psychotic spectrum symptoms in EDs. The unexpectedly high proportion of EDr suggests that a co‐morbid ED in other kinds of psychopathology is being overlooked.
Rescaling perceptual hand maps by visual‐tactile recalibration
Authors: Fuchs Xaver , Heed Tobias 
Published: November 2024

AbstractAfter concurrent visual and tactile stimuli have been presented repeatedly with a spatial offset, unisensory tactile stimuli, too, are perceived with a spatial bias towards the previously presented visual stimuli. This so‐called visual‐tactile ventriloquism aftereffect reflects crossmodal recalibration. As touch is intrinsically linked to body parts, we asked here whether recalibration occurs at the level of individual stimuli or at a higher, integrated, map‐like level. We applied tactile stimuli to participants' hidden left hand and simultaneously presented visual stimuli with spatial offsets that, if integrated with the tactile stimuli, implied a larger hand. After recalibration, participants pointed to tactile‐only stimuli and judged the distance between two tactile stimuli on the hand. The pattern of changes in tactile localization after recalibration was consistent with participants aiming at targets on an enlarged hand. This effect was evident also for new, tactile‐only locations that had not been paired with visual stimuli during recalibration. In contrast, distance judgements were not consistently affected by recalibration. The generalization of recalibration to new, non‐trained stimulus sites, but not across tasks and responses, suggests a link of low‐level multisensory processing and map‐like body representations that may, however, be purpose‐specific and not organized as a general‐purpose “body schema”.
Metabolic Regulation of Inflammation: Exploring the Potential Benefits of Itaconate in Autoimmune Disorders
Authors: Luo Yin , Jiang Li‐Yan , Liao Zhe‐Zhen , Wang Yuan‐Yuan , Wang Ya‐Di , Xiao Xin‐Hua 
Published: November 2024

ABSTRACTItaconic acid and its metabolites have demonstrated significant therapeutic potential in various immune diseases. Originating from the tricarboxylic acid cycle in immune cells, itaconic acid can modulate immune responses, diminish inflammation, and combat oxidative stress. Recent research has uncovered multiple mechanisms through which itaconic acid exerts its effects, including the inhibition of inflammatory cytokine production, activation of anti‐inflammatory pathways, and modulation of immune cell function by regulating cellular metabolism. Cellular actions are influenced by the modulation of metabolic pathways, such as inhibiting succinate dehydrogenase (SDH) activity or glycolysis, activation of nuclear‐factor‐E2‐related factor 2 (Nrf2), boosting cellular defences against oxidative stress, and suppression of immune cell inflammation through the NF‐κB pathway. This comprehensive review discusses the initiation, progression, and mechanisms of action of itaconic acid and its metabolites, highlighting their modulatory effects on various immune cell types. Additionally, it examines their involvement in immune disease like rheumatoid arthritis, multiple sclerosis, type 1 diabetes mellitus, and autoimmune hepatitis, offering greater understanding for creating new therapies for these ailments.