bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pakistan Comprehensive Fistula Classification: A Novel Scheme and Algorithm for Management of Palatal Fistula/Dehiscence
Authors: Fayyaz Ghulam Qadir , Gill Nauman Ahmad , Ishaq Irfan , Aslam Muhammad , Chaudry Ayesha , Ganatra Muhammad Ashraf , Obaid Obaidullah , Tarar Moazzam Nazeer , Chen Philip Kuo-Ting , Laub Donald Rudolph 
Published: November 2018

Background:
It is not easy to find a management-based classification of palatal fistula in the literature. A few attempts have been made to classify the wide variety of fistulae that do not describe the fistula details comprehensively and guide toward its management. The authors have come across a wide variety of fistulae that could not be classified according to any of the prevailing classification systems. The presented classification gives a clear and exact understanding of location and size of fistula/dehiscence. Palatal function has been included as one of the important determinants for devising a management plan. Based on this classification, the authors have proposed an algorithm that encompasses clear guidelines for surgical treatment of these fistulae.

Methods:
Over the past 15 years, the authors’ team operated on 2537 palatal fistula patients. The medical records of these patients were reviewed to determine the location, size, and velopharyngeal competence. A new classification and algorithm were developed.

Results:
Of 2537 patients, 2258 had midline fistulae, 208 had lateral fistulae, and 53 had subtotal fistulae. There were 18 patients with dehiscence. Recurrence developed in 181 patients.

Conclusion:
The authors believe that this classification and algorithm can help follow a practical approach to manage palatal fistulae and dehiscence.
Tomoelastography for the Evaluation of Pediatric Nonalcoholic Fatty Liver Disease
Authors: Hudert Christian A. , Tzschätzsch Heiko , Rudolph Birgit , Bläker Hendrik , Loddenkemper Christoph , Müller Hans-Peter , Henning Stephan , Bufler Philip , Hamm Bernd , Braun Jürgen , Holzhütter Hermann-Georg , Wiegand Susanna , Sack Ingolf , Guo Jing 
Published: November 2018

Objectives
Today, nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in children and adults alike. Yet, the noninvasive evaluation of disease severity remains a diagnostic challenge. In this study, we apply multifrequency magnetic resonance elastography (mMRE) for the quantification of liver steatosis and fibrosis in adolescents with NAFLD.

Methods
Fifty adolescents (age range, 10–17 years; mean BMI, 33.9 kg/m2; range, 21.4–42.1 kg/m2) with biopsy-proven NAFLD were included in this prospective study. Multifrequency magnetic resonance elastography was performed using external multifrequency vibrations of 30 to 60 Hz and tomoelastography postprocessing, resulting in penetration rate (a) and shear wave speed (c). Hepatic fat fraction was determined using Dixon method. The diagnostic accuracy of mMRE in grading liver steatosis and staging liver fibrosis was assessed by receiver operating characteristic curve analysis.

Results
Multifrequency magnetic resonance elastography parameters c and a were independently sensitive to fibrosis and steatosis, respectively, providing area under the receiver operating characteristic values of 0.79 (95% confidence interval [CI], 0.66–0.92), 0.91 (95% CI, 0.83–0.99), and 0.90 (95% CI, 0.80–0.99) for the detection of any (≥F1), moderate (≥F2), and advanced (≥F3) fibrosis, and 0.87 (95% CI, 0.76–0.97) and 0.87 (95% CI, 0.77–0.96) for the detection of moderate (≥S2) and severe (S3) steatosis.

Conclusions
One mMRE measurement provides 2 independent parameters with very good diagnostic accuracy in detecting moderate and advanced fibrosis as well as moderate and severe steatosis in pediatric NAFLD.
Full title:Age analysis and growth patterns ofTenualosa ilishausing otolith examination and length-weight relationships from different regions of Bangladesh
Authors: Uddin Ahmed Borhan , Ahammad A. K. Shakur , Shahjahan  , Kumar Datta Biraj , Rabbi Fazla , Ashraful Alam Mohammad , Bashar Abul , Mahmud Yahia 
Published: November 2018

AbstractThe assessment of age and growth patterns provides crucial information on numerous aspects of the population dynamics in fish, which can, in turn, be used to determine a sustainable fishing rate and inform effective resource management practices. However, studies on the age and growth pattern ofTenualosa ilisha(commonly referred to as hilsa) are plagued by a lack of essential information; addressing this data gap is the aim of the present study. Six diverse habitats across Bangladesh were chosen as sampling sites for hilsa collection. For age determinations, the lunar rings in the otolith of the hilsa fish that are periodically-deposited in accordance with the lunar cycle were used to reflect 14-day increments of time. The length and weight of each fish were recorded prior to otolith extraction. The resulting otoliths were polished to enable the visualization and quantification of their lunar rings with a high-magnification microscope. Except for the Kali River and Gaglajur Haor samples, the age of the fish correlated strongly with both their length and weight (r> 0.95;p< 0.05). Again, aside from those from the Kali River and Gaglajur Haor, all of the samples exhibited positive allometric growth patterns (b> 3) with the fish from the Tetulia River being the most positive (b= 3.48). The causes these variations are not yet clearly understood, however; the nutrient availability, environmental variation, and genetic-environmental interactions are likely contributors to the diversities displayed by the hilsa from different regions of Bangladesh.
A spatially regulated GTPase cycle of Rheb controls growth factor signaling to mTORC1
Authors: Kovacevic Marija , Klein Christian H. , Roßmannek Lisaweta , Konitsiotis Antonios D. , Stanoev Angel , Kraemer Astrid U. , Bastiaens Philippe I. H. 
Published: November 2018

ABSTRACTGrowth factors initiate anabolism by activating mechanistic target of rapamycin complex 1 (mTORC1) via the small GTPase Rheb. We show that the GTPase cycle of Rheb is spatially regulated by the interaction with its GDI-like solubilizing factor (GSF) – PDEδ. Arl2-GTP mediated localized release of cytosolic Rheb-GTP from PDEδ deposits it onto perinuclear membranes where it forms a complex with mTORC1. The membrane associated GTPase activating protein (GAP) TSC2 hydrolyzes Rheb-GTP, weakening the interaction with mTOR. Rheb-GDP is readily released into the cytosol where it is maintained soluble by interaction with PDEδ. This solubilized Rheb is re-activated by nucleotide exchange to be re-deposited by Arl2-mediated release onto perinuclear membranes. This spatial GTPase cycle thereby enables mTORC1 activation to be solely controlled by growth factor induced inactivation of TSC2. The coupling between mTOR activation and spatially regulated Rheb nucleotide exchange makes growth factor induced proliferation critically dependent on PDEδ expression.
Individual, organizational and social level antecedents of work-family enrichment: Does gender acts as a moderator?
Authors: Mishra Pavitra , Bhatnagar Jyotsna 
Published: November 2018

PurposeThis study aims to fulfill the need to explore positive side of work–family interface, especially in emerging economies like India. The authors assessed the relationships of individual (family role salience), organizational (work–family culture) and social (community support) antecedents to work-to-family enrichment. They also examined whether gender moderated the relationship between the three antecedents and work-to-family enrichment.Design/methodology/approachData were collected on a questionnaire scale from 487 employees.FindingsIt has been found that family role salience, supportive work-family culture and community support were directly related to work-to-family enrichment. Gender did not influence the relationship between work-family culture and work-to-family enrichment. However, relationships between family role salience and work-to-family enrichment, and between community support and work-to-family enrichment, were stronger in case of the male employees. The evolving nature of gender and integration of work-family-community domain provide insights into managers and policymakers about the importance of family and community in the organizations.Practical implicationsThe study builds a business case for facilitating a positive work-family culture in India for both male and female employees. The results point to the transitioning socio-cultural scenario of India, which advocates more similarities than differences in modern gender role expectations and identity. The current study emphasizes that while formulating policy, managers and policymakers should keep in mind evolving preferences of both the genders.Originality/valueThe research provides a holistic view of how individual-, organizational- and social-level factors may affect employees’ work–family enrichment in India. It also highlights the changing role of gender. Theoretical and practical limitations are also discussed.
Acquirer’s corporate reputation in cross-border acquisitions: the moderating effect of country image
Authors: Matarazzo Michela , Lanzilli Giulia , Resciniti Riccardo 
Published: November 2018

Purpose
The purpose of this paper is to investigate whether, in the context of a cross-border acquisition, the acquirer’s country image (CI) could moderate the relationship between the acquirer’s corporate reputation (CR) and consumers’ repurchase intentions towards the products of the post-acquisition target.

Design/methodology/approach
The authors examined the roles played by the acquirer’s CR and the acquirer’s CI on consumer behaviour by considering an Italian target firm with a high reputation and comparing four foreign acquiring firms with different combinations of CR (poor/good) and CI (high/low).

Findings
It was found that both CR and CI have a significant impact on Italian consumers’ intention to repurchase the products of the post-acquisition target. Furthermore, the results show a greater increase in consumers’ repurchase intentions when a good reputation of the acquirer is paired with a high CI for the acquirer, but a high CI cannot compensate for a poor CR.

Originality/value
The research investigates, in the context of cross-border acquisitions (CBAs), the impact of the acquirer’s CR and the acquirer’s CI on the host country consumers’ repurchase intentions after the CBA, which has not previously been thoroughly examined. It can help managers to understand the conditions under which CBAs will be favourably evaluated.
The impact of individual entrepreneurial orientation and education on generation Z’s intention towards entrepreneurship
Authors: Frunzaru Valeriu , Cismaru Diana-Maria 
Published: November 2018

Purpose
The purpose of this paper is to investigate the level of entrepreneurial features and the intention towards entrepreneurship (ITE) of generation Z students. The paper also explores if entrepreneurial education (EE) plays a role in the development of individual entrepreneurship orientation (IEO) and in increasing the ITE of the generation Z students.

Design/methodology/approach
The research consists of a survey of students in the fields of marketing and communication (n = 590) conducted in January 2018. The authors used SPSS software to test the reliability of scales that measure IEO, ITE, the need for achievement, structural behaviour, self-efficacy and the attitude towards job flexibility, and to run Pearson correlation, multiple linear regression and t test to test the hypotheses.

Findings
The findings show that generation Z students have similar ITE and EE to colleagues from other generations. EE has a significant impact on increasing both IEO and ITE. Nevertheless, generation Z students have a higher need for achievement, a lower self-efficacy and are more open to a flexible labour market.

Originality/value
This paper explores a topic which has received little attention: the interest and capacity of generation Z students to develop their own business. The paper also analyses whether the EE offered by universities can play a role in this regard.
Transcomputability, (Glanville’s corollary of) Ashby’s law of requisite variety and epistemic processes
Authors: Fischer Thomas 
Published: November 2018

Purpose
Ranulph Glanville has argued that ambitions of strict control are misplaced in epistemic processes such as learning and designing. Among other reasons, he has presented quantitative arguments for this ethical position. As a part of these arguments, Glanville claimed that strict control even of modest systems transcends the computational limits of our planet. The purpose of this paper is to review the related discourse and to examine the soundness of this claim.

Design/methodology/approach
Related literature is reviewed and pertinent lines of reasoning are illustrated and critically examined using examples and straightforward language.

Findings
The claim that even modest epistemic processes transcend the computational means of our planet is challenged. The recommendation to assume out-of-control postures in epistemic processes, however, is maintained on ethical rather than on quantitative grounds.

Research limitations/implications
The presented reasoning is limited in as far as it is ultimately based on an ethical standpoint.

Originality/value
This paper summarizes an important cybernetic discourse and dispels the notion therein that epistemic processes necessarily involve computational demands of astronomical proportions. Furthermore, this paper presents a rare discussion of Glanville’s Corollary of Ashby’s Law of Requisite Variety.
Macroeconomic significance of transaction costs in microfinance intermediation
Authors: Swamy Vighneswara 
Published: November 2018

PurposeThe purpose of this paper is to analyze the macroeconomic significance of transaction costs in microfinance intermediation and explain how the deposit mobilization and micro lending impact the microfinance transaction costs. It presents some empirical evidence as building blocks for the theory of financial intermediation that aims at strengthening the efficiency of financial intermediation in the context of preferential credit and or the microfinance sector.Design/methodology/approachThe study uses the panel data consisting of different groups of banks in India (such as public sector banks, private banks and foreign banks) data across a period from March 1993 to March 2009 to estimate the panel VAR model to determine the determinants of transaction cost model in financial intermediation. The study also uses the panel Granger causality analysis to test the direction of causation to know the behavior of the operating expense of the banks in their financial intermediation process.FindingsThe study reveals that there is a positive direct relationship between operating expense and priority sector lending by banks. The findings show that the transaction costs act as a barrier for the banking firms in microfinance intermediation; and, the banks are able to manage the transaction costs of microfinance intermediation with an increase in overall deposit mobilization and increased non-microfinance lending. The study recommends that there is a need to upscale the functional efficiency of microfinance intermediaries.Originality/valueThis study offers to bridge the research gap and adds novel information to the literature on microfinance intermediation. It is the first empirical paper showing the macroeconomic significance of transaction costs in microfinance intermediation.
Hydrogen peroxide pre-treatment enhances antioxidant properties and free radical scavenging activities of tree bean (Parkia roxburghii G. Don) seeds and pods during storage
Authors: Devi Mayengbam Premi , Sahoo Manas Ranjan , Kuna Aparna , Dasgupta Madhumita , Mandarapu Sowmya , Deb Prahlad , Prakash Narendra 
Published: November 2018

Purpose
This study aims to examine the effects of various physical and chemical pre-treatments on antioxidant properties of tree bean (Parkia roxburghii G. Don) in combination with storage conditions.

Design/methodology/approach
The whole pods and seeds of tree bean were treated with gamma rays (γ-rays), sodium hypochlorite (NaOCl), chlorine dioxide (ClO2) and hydrogen peroxide (H2O2) and stored at room temperature (RT, 25°C) for 30 days. The physical and chemical pre-treated seeds and pods were compared with the same stored at RT and refrigerated storage at 4°C and −20°C. During storage, physical (moisture content) and antioxidants like total phenolics, ascorbate content, reduced glutathione, total flavonoids, along with free radical scavenging activities (FRSA) were measured.

Findings
Chemical pre-treatments with NaOCl, ClO2 and H2O2 significantly accelerated (p = 0.05) the total phenolics (1.9 mg/g FW in seeds and 2.4 mg/g FW in pods), flavonoids content (0.3 mg/g FW each in seeds and pods) and ABTS activities (73.3 per cent in seeds and 92.3 per cent in pods) at 30 days of storage. A significant decrease (p = 0.05) in ascorbate content (6.1 mg/g FW in seeds and 3.5 mg/g FW in pods), reduced glutathione (5.1 mg/g FW in seeds and 3.7 mg/g FW in pods), FRAP (0.3 mg equi Fe/g FW in seeds and 0.4 mg equi Fe/g FW in pods) and reducing power (1.8 mg/g FW in seeds and 3.7 mg/g FW in pods) was observed under all the treatments at 30 days of storage. However, DPPH increased under γ-irradiation and decreased under chemical pre-treatments, storage at RT and refrigerated storage. The overall result showed that pre-treatment of H2O2 at 10-20 mM maintains antioxidants and radical scavenging activities in tree bean during storage.

Originality/value
The application of H2O2 at 10-20 mM prior to storage of tree bean maintains the physical, antioxidant properties and FRSA in tree bean seeds and pods as compared to natural ambient conditions. Hence, this technique will help in improving the keeping quality of this legume and avoid spoilage after harvest for an extended period.
Are computers better than smartphones for web survey responses?
Authors: Ha Louisa S. , Zhang Chenjie 
Published: November 2018

Purpose
The purpose of this paper is to examine the effect of smartphones and computers as web survey entry response devices on the quality of responses in different question formats and across different survey invitations delivery modes. The respondents’ preference of device and the response immediacy were also compared.

Design/methodology/approach
Two field experiments were conducted with a cluster sampling and a census of all students in a public university in the USA.

Findings
Device effect on response quality was only found when using computer-aided self-interviews, but not in e-mail delivered web surveys. Even though the computer was the preferred device, but the smartphone’s immediate response was significantly higher than the computer.

Research limitations/implications
The sample was restricted to college students who are more proficient users of smartphones and have high access to computers. But the direct comparison in the two studies using the same population increases the internal validity of the study comparing different web survey delivery modes.

Practical implications
Because of the minor differences in device on response quality, researchers can consider using more smartphones for field work such as computer-aided self-interviews to complement e-mail delivered surveys.

Originality/value
This is the first study that compares the response device effects of computer-aided self-interviews and e-mailed delivered web surveys. Because web surveys are increasingly used and various devices are being used to collect data, how respondents behave in different devices and the strengths and weaknesses of different methods of delivery survey help researchers to improve data quality and develop effective web survey delivery and participant recruitment.
Cancer risk in 892 089 patients with psoriasis in Korea: A nationwide population‐based cohort study
Authors: Lee Ji Hyun , Kim Hyo Jung , Han Kyung Do , Kim Ha‐Na , Park Young Min , Lee Jun Young , Park Yong‐Gyu , Lee Young Bok 
Published: November 2018

AbstractThe relationship between psoriasis and cancer has not yet been established. The aim of this study was to evaluate the association of psoriasis with certain cancers using national statistics. All patients with psoriasis (n = 892 089; 51.7% male) and age‐ and sex‐matched control subjects (n = 4 460 445) at a 5:1 ratio were enrolled using data from the National Health Insurance Service between 2007 and 2014 in Korea. In psoriatic subjects, overall cancer risk was higher than for subjects without psoriasis after adjusting for income level, diabetes, hypertension, dyslipidemia and place of residence (hazard ratio, 1.065; 95% CI, 1.049–1.081). The risk of cancer increased in the following order: prostate, thyroid, liver, ovarian, lung, leukemia, skin, multiple myeloma, lymphoma and testicular. The severity and sex of psoriatic patients also had different cancer risks. In psoriatic patients, a slightly increased risk for specific malignant neoplasms was shown. Therefore, periodic screening for cancer risk is recommended in patients with psoriasis.
The Impact of Credit Policy on Rice Production in Myanmar
Authors: Aung Nilar , Nguyen Hoa‐Thi‐Minh , Sparrow Robert 
Published: November 2018

AbstractRural finance has long been an important tool for poverty reduction and rural development by donors and governments, but the impacts have been controversial. Measuring impact is challenging due to identification problems caused by selection bias and governments’ targeted interventions, while randomised trial data are scarce and limited to contexts where little to no rural finance exists. Using an author‐collected dataset, we provide insights on a large‐scale long‐lasting subsidised rice credit programme in Myanmar, one of the poorest and, until recently, most economically isolated countries in Asia. Identification relies on a fuzzy regression discontinuity design, exploiting an arbitrary element to the credit provision rule which is based on rice landholding size. Although we find little evidence that rice yield or output is increased, we do see that the programme has some positive effects on total household income, suggesting a positive spillover effect on other farm income activities.