bluuebunny/crossref_metadata_2025_split huggingface dataset:
Isolated myxopapillary ependymoma of the fourth ventricle: illustrative case
Authors: Mldie Alemu A. , Baleh Abat S. , Molla Henok T. , Yesuf Ermias F. , Mekuria Bereket H. 
Published: November 2024

BACKGROUND
A myxopapillary ependymoma (MPE) is a distinctive ependymoma variant that arises exclusively in the conus medullaris or the filum terminale. There are few case reports of intracranial occurrences, with even rarer occurrences in the fourth ventricle.

OBSERVATIONS
A 31-year-old female patient presented with difficulty in maintaining her balance and headaches of 3 months’ duration. Brain magnetic resonance imaging showed a fourth ventricle mass with obstructive hydrocephalus. Surgical removal of the tumor was performed. The biopsy of the tumor revealed the histological feature of MPE, World Health Organization grade 2. To the authors’ knowledge, this is the fourteenth reported case of primary intracranial MPE and the fifth reported case of MPE originating from the fourth ventricle.

LESSONS
MPEs are known for their notorious adhesion and infiltration of adjacent neural tissue; therefore, the clinical outcome of fourth ventricle MPEs depends on their relationship with the floor of the fourth ventricle.
https://thejns.org/doi/10.3171/CASE24571
Open thrombectomy and reconstruction of the rolandic vein in a parasagittal meningioma: recovering motor evoked potentials. Illustrative case
Authors: Eduardo da Silva Carlos , Vidaletti Tamara , Domenico Marrone Carlo , Pereira Secco Yuri , Clara Thibes Ana 
Published: November 2024

BACKGROUND
Parasagittal meningiomas commonly invade the superior sagittal sinus (SSS) and cortical veins. Reconstructing the veins can be challenging after radical meningioma removal, especially when major venous sinuses and veins are involved. The authors present a video showcasing the reconstruction of the rolandic vein during surgery for a large parasagittal meningioma. The video shows the surgical technique and motor evoked potential recovery after venous drainage returns to normal.

OBSERVATIONS
A 59-year-old woman had been experiencing progressive weakness in her right lower limb over the past year. Magnetic resonance imaging revealed a consistent enhanced mass in the left parasagittal region over the motor area, indicating meningioma. Magnetic resonance venography showed a complete blockage of the SSS. The patient experienced the loss of motor evoked potentials after tumor removal and thrombosis of the rolandic vein. An open thrombectomy was performed, and the vein was reconnected to the SSS. The patient recovered her basal motor evoked potential.

LESSONS
The video of a rolandic vein reconstruction emphasizes the significance of preserving and restoring venous blood flow in eloquent areas. Monitoring is crucial during meningioma surgery involving the SSS and cortical veins in the motor area to identify and reverse any motor and sensory deficits, ensuring optimal resection while maintaining the patient’s quality of life.
https://thejns.org/doi/10.3171/CASE24601
HOW DO WE REVIVE AND DEVELOP OUR CITIES?
Authors: Habrel Mykola 
Published: November 2024

The article presents the results of a review of the monograph “Complex city reconstruction: models and methods” by Dr. Tech. Sciences, Professor Pleshkanovska A.M. The monograph outlines the fundamentals of the methodology for the comprehensive reconstruction of the city as a condition for its sustainable harmonious development. Reconstruction activities in various types, forms, methods and means of implementation are considered as an integral component of the city’s life cycle. The theoretical foundations and practical testing of the rationale for choosing the priority type of reconstruction, as well as individual author’s methods for the complex reconstruction of urban subsystems are presented.
The book is intended for specialists in the field of urban planning, spatial planning and architecture, teachers, undergraduate and graduate students of universities in the relevant field, as well as ordinary readers interested in the existence and reconstruction of urban systems.
PERSPECTIVES OF INTEGRATION OF WATERFRONT AREAS INTO RECREATIONAL URBAN SPACES ON THE EXAMPLE OF THE RIVER PRUT AND THE STREAMS KLOKUCHKA, MOLNYTSIA, SHUBRANETS, POTIK IN CHERNIVTSI
Authors: Korotun Iryna , Herych Kateryna , Dovganiuk Anatolii 
Published: November 2024

Riverbeds and riverbanks need measures to deepen shallow channels, clear the banks of debris and brush, regenerate coastal areas and redevelop them in accordance with modern approaches to accessibility and sustainable mobility.
Rivers, streams, springs, lakes, and other water areas located in urban areas are important components of the landscape structure and are significant for maintaining the ecological balance of the settlement. The integration of waterfront areas into recreational urban spaces is an important factor of creating a harmonious and comfortable urban environment. The organisation of rational exploitation and maintenance of engineering structures, sanitary conditions and green spaces of riverine areas provides conditions for the existence and preservation of biogeocenosis centres.
The regeneration of the coastal areas of small rivers and streams offers opportunities to create modern anthropogenic urban landscapes and public spaces, ensure the formation of recreational areas, reduce flood threats and create conditions for the existence of urban biogeocenoses.
The coastal and waterfront areas of small rivers and streams have significant potential for creating long-distance pedestrian and bicycle routes. These routes can be used year-round and become a factor of the development of cultural and entrepreneurial activities of small and medium-sized businesses around them. It should be noted that coastal improvement works are supported by activities that are aimed to protect and strengthen the coastline.
The article reviews the current possibilities of regeneration and integration of waterfront areas into urban spaces, analysing the relevant activities in cities around the world. The provisions of the Water Code, which discourage the integration of the territories surrounding water areas into the urban planning structures, are highlighted. The prospects of integrating the riverine territory of the rivers Prut, Klockuchka and Molnytsia into the recreational, residential, transport and pedestrian structures of Chernivtsi are considered. The architectural principles of functional and planning organisation and renovation of the banks of small rivers and ways of using their natural and recreational potential to improve the level of comfort and mobility in the city are determined.
PENERAPAN MULTI AKAD DALAM KONTRAK GADAI DI BANK JATIM SYARIAH CAPEM SAMPANG
Authors: Ramin Moh. , Rofiqi Rofiqi , Ali Wafa Moh. 
Published: November 2024

Peneliti menemukan bahwa penerapan multi akad dalam proses Gadai Emas di Bank Jatim Syariah Capem Sampang melalui beberapa akad yaitu; akad Qardh, akad Rahn, dan akad ijarah sudah sesuai dengan Fatwa DSN-MUI atau sesuai dengan prinsip syariah, yaitu ada akad Qardh sebagai akad pemberian pinjaman murni pada nasabah, akad Rahn sebagai akad yang disepakati nasabah sebagai penyerahan barang jaminan untuk disimpan oleh Bank dengan diikuti akad selanjutnya yaitu akad ijarah sebagai akad yang melengkapi kontrak gadai dan alternative Bank untuk mendapatkan ujroh yang dihitung berdasarkan krakter jaminan. Dalam penelitian ini, pengumpulan data dilakukan dengan cara studi dokumentatif dan wawancara langsung dengan account officer gadai sebagai pihak yang menangani proses pembiayaan Gadai Emas. Wawancara dilakukan untuk menggali informasi terkait permasalahan yang peneliti angkat. Data yang terkumpul dianalisis dengan menggunakan metode analisis deskripstif kualitatif.
Assessment Of Spatiotemporal Variation In Inter-State Passenger Flow From Katsina, Katsina State, Nigeria
Authors: Yahaya Olanrewaju Yusuf , Shafii Husaini , Ubogu Andrew Egba 
Published: November 2024

This paper examines the nature, pattern, and spatiotemporal variation of inter-state passenger movement from Katsina to other states across the country. Two major terminals were purposefully selected for the study, which are the Nigerian Union of Road Transport Workers (NURTW) and Katsina State Transport Authority (KTSTA). Questionnaires were systemically administered to departing passengers. Information on passenger flow was collected from the passenger register at the motor parks. A flow line map was used to show the direction of the flow, while a bar graph was used to show the volume or magnitude and temporal variation of passenger movement from Katsina to other states across the country. The findings reveal that the majority of the passengers were males who were married, and most of them were traders and civil servants; thus, work- or business-related trips account for most of the reasons for travelling. The findings reveal that the NURTW terminal has a wider spatial coverage of 11 states, while the KTSTA terminal has a spatial coverage of 9 states. Kano State is the most popular destination, followed by Kaduna and Abuja. Generally, the findings show a seasonal pattern of passenger flow with higher numbers in the later months of the year (October to December) and lower numbers in the middle of the year (June and July). Recommendations include the enhancement of transport infrastructures to cater to work- or business-related trips, seasonal adjustment, passenger demographic consideration, and promotion of off-peak travel. This is to ensure a more efficient and responsive transport system that meets the needs of travellers and maximises customer satisfaction.
SOCIALIZATION OF THE USE OF HEALTH INSURANCE PROGRAMS TO REDUCE THE ECONOMIC BURDEN OF PATIENTS
Authors: ARIANI Meiliyah , MINARNI Sarida , PURNAMASARI Melan Susanty , Zulhawati Zulhawati , DEWI Kurnia Sari , UTAMA Zahera Mega 
Published: November 2024

This community service aims to be able to provide information or knowledge to the public who use the national health insurance how to apply the principles of quality control and cost control applied in health facilities to control inefficiencies so that they can provide JKN continuity and equality in getting access to health services, so JKN collaborates with health facilities to always be effective, efficient, rational, in accordance with the needs of patients and synergize with the local government to carry out supervision and coaching. The methods used in this community service are lectures, questions and answers, and discussions. The target of this community service activity is especially for BPJS users in Jatiasih sub-district, South Bekasi. With this socialization, it is hoped that the people of Jatiasih District will better understand the importance of the health insurance program and can make maximum use of it to reduce the economic burden when they need health services. This socialization went smoothly and the community was very enthusiastic about participating in the activity. which can be seen from the results of the pretest and posttest that the participants have filled in.
SOCIALIZATION OF PKM EDUCATES UB BOSS FARM FARMERS IN MAKING BIOGAS AS ENVIRONMENTALLY FRIENDLY RENEWABLE ENERGY FOR TOFU PRODUCTION
Authors: MAHARANI Maya Dewi , NINGRUM Raden Yusia Wulandari 
Published: November 2024

Biogas is a gas produced from the process of decomposing organic materials by microorganisms under anaerobic conditions. Biogas can be burned like LPG and become an alternative source of renewable energy that is environmentally friendly. Biogas contains 60% CH4 gas (methane); 38% CO2 gas (Carbon Dioxide); and 2% N2, O2, H2, H2S gas. The name of the partner is UB BoSS Farm with a business as a Cattle-Buffalo Farmer as well as producing tofu which is located in Cibadak Village, Ciampea District, Bogor Regency. The number of cows is 40 and 2 buffaloes, so that the potential for wet waste produced is 420 kg/day which is equivalent to 117,600 liters/day of biogas; solid total of each tail is 16% and solid volatility is 77% TS. The stages of implementing PKM activities that have been carried out include discussion, socialization, and evaluation of activities (pre-test and post-test). The results of PKM activities showed a change in the level of knowledge of participants regarding what factors were influential, and the stages of the biogas manufacturing process from 20% to 93.33%. The post-test results also showed that most of the participants (86.67%) now have knowledge about raw materials around the business area that can be used as biogas.
PENILAIAN KELAIKAN MANAJEMEN HIGIENE DAN SANITASI DI DEPOT AIR MINUM
Authors: Rohimin Mohammad , Hanif Muhammad , Putri Marsha Savira Agatha 
Published: November 2024

Air minum adalah air yang diolah dengan teknik pengolahan atau tanpa teknik pengolahan yang memenuhi syarat kesehatan serta dapat langsung diminum. DAM yaitu badan usaha yang mengelola air minum sebagai keperluan masyarakat dalam bentuk curah, serta dikemas dalam kemasan botol sebanyak 19 liter, Kurangnya pengawasan serta pengetahuan penjamah terhadap higiene dan sanitasi menjadikan kualitas air minum isi ulang tidak memenuhi Permenkes No. 492 Tahun 2014 tentang Persyaratan Kualitas Air Minum, Metode ini menggunakan data primer yakni penilaian inspeksi sanitasi secara langsung di Depot Air Minum di Kecamatan Solokuro, Kualitas Air yang di uji dalam penelitian ini meliputi pH, TDS, COD, total coliform sesuai dengan setandar baku mutu Permenkes RI No. 43 Tahun 2014.Pada proses penelitian ini di temukan bahwa depot air minum di kecamatan solokuro kurang memenuhi standar baku mutu air minum yang ditentukan hal ini dikarenakan kualitasair minum yang di uji melebihi ambang batas yang sudah di tentukan.Penilaian kelaikan higiene sanitasi di kecamatan solokuro cenderung baik dan memenuhi standar baku mutu yang di tetapkan sedangkan beberapa sampel air minum di kecamatan solokuro belum memenuhi standar baku mutu air minum yang di tentukan.
HUBUNGAN MUTU PELAYANAN TERHADAP KUNJUNGAN ULANG PASIEN BPJS RAWAT JALAN
Authors: Faradila Mulya Dwi , Rukmana Nova Mega , Putri Dian Utama Pratiwi 
Published: November 2024

Rendahnya angka kunjungan berobat ke fasilitas kesehatan merupakan salah satu faktor yang mempengaruhi derajat kesehatan di Indonesia. Pada tahun 2023 UPTD Puskesmas Kedondong mengalami penurunan cakupan peserta BPJS sebesar 3,789 peserta yang melakukan penonaktifan kepesertaan dan pemindahan ke FKTP lainnya. Mutu pelayanan kesehatan mengacu pada kesempurnaan pelayanan kesehatan yang membawa rasa kepuasan bagi setiap pasien. Tujuan penelitian untuk mengetahui hubungan mutu pelayanan terhadap kunjungan ulang pasien BPJS Rawat jalan di UPTD Puskesmas Kedondong Kabupaten Pesawaran Tahun 2023. Metode penelitian adalah penelitian kuantitatif pendekatan cross sectional.jumlah responden dalam penelitian ini sebanyak 77 pasien BPJS yang melakukan kunjungan rawat jalan, menggunakan teknik Accidental sampling.Penelitian telah dilakukan di UPTD Puskesmas Kedondong pada 3-17 Juli 2023. Pengumpulan data menggunakan kuesioner. Hasil penelitian univariat didapatkan kunjungan ulang sebanyak 44 (57,1%), diketahui responden dengan bukti fisik baik sebanyak 45 (58,4%), responden dengan keandalan tidak baik sebanyak 41 (53,2%), responden dengan daya tanggap tidak baik sebanyak 42 (54,5%), responden dengan jaminan baik sebanyak 40 (51,9%), responden dengan empati tidak baik sebanyak 44 (57,1%). Analisis bivariat ada hubungan bukti fisik (p-value=0,002), keandalan (p-value=0,023), daya tanggap (p-value=0,037), jaminan (p-value=0,032), dan empati (p-value=0,002) dengan kunjungan ulang pasien BPJS di pelayanan rawat jalan UPTD Puskesmas Kedondong tahun 2023. Saran bagi puskesmas dapat memperhatikan keluhan yang disampaikan oleh pasien seperti ketidaknyamanan yang dirasakan oleh pasien, karena semua ini sangat berdampak terhadap mutu pelayanan kesehatan.
Sex-specific NLRP3 activation in neutrophils promotes neutrophil recruitment and NETosis in the murine model of diffuse alveolar hemorrhage
Authors: Jarrot Pierre-André , Kim Jiyoun , Chan William , Heger Lukas , Schommer Nicolas , Cunin Pierre , Silva Camila M. S. , Robert Stéphane , Nigrovic Peter A. , Ewenstein Bruce , Wagner Denisa D. 
Published: November 2024

ObjectivesDiffuse alveolar hemorrhage (DAH) is a life-threatening complication of systemic lupus erythematosus and small vessel vasculitis. We previously showed that neutrophil extracellular traps (NETs) were associated with the pathogenesis of pristane-induced DAH and demonstrated that neutrophil NOD-like receptor family pyrin domain containing 3 (NLRP3) inflammasome assembly participated in NET generation under sterile stimulation. We investigated whether NLRP3 inflammasome assembly in neutrophils may drive pulmonary NETosis in a mouse model of pristane-induced DAH.MethodsC57BL/6J mice received a single intraperitoneal injection of 0.5mL of pristane. Neutrophil NLRP3 inflammasome assembly and NETs were characterized by immunofluorescence staining of apoptosis-associated speck-like protein a CARD (ASC), co-staining of DNA, and citrullinated histones, respectively. Clinical status of mice was assessed 11 days after pristane injection by measurement of arterial oxygen saturation and of weight loss; severity of lung injury was determined using a quantification score from hematoxylin-eosin-stained slides.ResultsPristane induced ASC speck formation in neutrophils and we confirmed that NLRP3 inflammasome was involved in NET generation after pristane stimulation in vitro. NLRP3 deficiency reduced the severity of pristane-induced DAH in female, but not male mice. Interestingly, NLRP3 deficiency reduced the number of neutrophils and NETs in the lungs of females compared to males.ConclusionsOur results suggest a link between female sex-specific NLRP3 inflammasome activation and subsequent pulmonary NETosis in the development of pristane-induced DAH. Therefore, we identified NLRP3 inflammasome as a potential new therapeutic target in this severe complication of pro-female autoimmune disease for which specific inhibitors of NLRP3 are currently developed.
Thymic hyperplasia after autologous hematopoietic stem cell transplantation in multiple sclerosis: a case series
Authors: Mariottini Alice , Boncompagni Riccardo , Cozzi Diletta , Simonetti Edoardo , Repice Anna Maria , Damato Valentina , Giordano Mirella , Miele Vittorio , Nozzoli Chiara , Massacesi Luca 
Published: November 2024

IntroductionReactivation of thymopoiesis in adult patients with autoimmune disorders treated with autologous haematopoietic stem cell transplantation (AHSCT) is supported by studies exploring immunoreconstitution. Radiological evidence of thymic hyperplasia after AHSCT was previously reported in patients with systemic sclerosis, but, to our knowledge, it has not been described in multiple sclerosis (MS), where premature thymic involution has been observed and immunosenescence might be accelerated by disease-modifying treatments (DMTs).Participants and methodsmonocentric case series including MS patients who performed a chest CT scan for clinical purposes after having received AHSCT (BEAM/ATG regimen) for aggressive MS failing DMTs. Chest CT exams were reviewed by a thoracic radiologist: thymic hyperplasia was defined as a rounded mass in the thymic loggia with a density around 40 Hounsfield Units (HU) and thickness &gt;1.3 cm.ResultsFifteen MS patients were included; the median time interval between AHSCT and chest CT scan was 2 (range 1-18) months. All the patients were free from new inflammatory events and DMTs over a median follow-up of 36 months (range 12-84) after AHSCT. Thymic hyperplasia was detected in 3/15 (20%) cases in an exam taken 1 to 3 months after AHSCT; all these patients were females, and aged 30 to 40 years. Lung infections and secondary autoimmunity were diagnosed in 5 and 1 cases, respectively, none of which showed thymic hyperplasia. No associations between thymic hyperplasia and clinical-demographic characteristics or post-AHSCT outcomes were observed.ConclusionsThymic hyperplasia was detected in 20% of MS patients recently treated with AHSCT. These results are consistent with previous immunological studies showing that AHSCT promotes thymus reactivation in MS patients, further supporting de-novo thymopoiesis as a cornerstone of immune reconstitution after AHSCT in this population.
Coexistent pleural effusion is found to be associated with aggravated subclinical myocardial injury in systemic lupus erythematous using cardiovascular magnetic resonance imaging
Authors: Zhi Yang , Zhang Tian-yue , Zhu Yong , Zou Hao , You Yi , Wen Miao , Wang Zhong , Gao Liang-chao , Bing Fu , Pan Shu-yue 
Published: November 2024

ObjectivePleural effusion (PE) is a common pulmonary manifestation in patients with systemic lupus erythematosus (SLE), and is associated with disease activity. However, little is known regarding the additive effects of PE on cardiac function. Therefore, this study aimed to investigate multi-parameter cardiovascular magnetic resonance imaging (CMR) findings in SLE patients with PE and to explore whether cardiac involvement is associated with PE.MethodsPatients with SLE and age-matched/sex-matched healthy controls were included in this study. Patients with SLE were diagnosed according to the 2019 European League Against Rheumatism/American College of Rheumatology classification criteria. Moreover, the PE diagnosis was based on computed tomography, and the height of the effusion was &gt; 5 mm. All enrolled individuals underwent CMR imaging, including cine and late gadolinium enhancement (LGE), T1, and T2 mapping imaging. The left and right ventricular function, LGE, T1, extracellular volume (ECV), and T2 values were evaluated.ResultsA total of 111 patients with SLE were enrolled, of whom 26 (23.42%) had PE. White cell count, hemoglobin, CRP, ESR, and lactate dehydrogenase levels were higher in SLE patients with PE than in SLE patients without PE (P&lt;0.05). LGE was more prevalent in SLE patients with PE compared with those without PE (P&lt;0.001). In addition, Native T1 (1348 ± 65 ms vs. 1284 ± 67 ms vs. 1261 ± 41 ms; P&lt;0.001), ECV (31.92 ± 4.16% vs. 28.61 ± 3.60% vs. 26.54 ± 2.94%; P&lt;0.001), and T2 (44.76 ± 3.68 ms vs. 41.96 ± 3.62 ms vs. 39.21 ± 2.85 ms; P&lt;0.001) values were high in SLE patients with PE, intermediate in SLE patients without PE, and the lowest in the control group. Linear regression analysis demonstrated that PE was independently associated with LGE (β=0.329; P&lt;0.05), T1 (β=0.346; P&lt;0.05), ECV (β=0.353; P&lt;0.05), and T2 (β=0.201; P&lt;0.05).ConclusionsSLE patients with PE have a higher prevalence of LGE and more diffuse myocardial fibrosis and edema than SLE patients without PE. Moreover, PE is associated with increased diffuse interstitial fibrosis and edema.