bluuebunny/crossref_metadata_2025_split huggingface dataset:
Home-Based Kidney Care, Patient Activation, and Risk Factors for CKD Progression in Zuni Indians
Authors: Nelson Robert G. , Pankratz V. Shane , Ghahate Donica M. , Bobelu Jeanette , Faber Thomas , Shah Vallabh O. 
Published: November 2018

Background and objectives
The burden of CKD is greater in ethnic and racial minorities and persons living in rural communities, where access to care is limited.

Design, setting, participants, & measurements
A 12-month clinical trial was performed in 98 rural adult Zuni Indians with CKD to examine the efficacy of a home-based kidney care program. Participants were randomized by household to receive usual care or home-based care. After initial lifestyle coaching, the intervention group received frequent additional reinforcement by community health representatives about adherence to medicines, diet and exercise, self-monitoring, and coping strategies for living with stress. The primary outcome was change in patient activation score, which assesses a participant’s knowledge, skill, and confidence in managing his/her own health and health care.

Results
Of 125 randomized individuals (63 intervention and 62 usual care), 98 (78%; 50 intervention and 48 usual care) completed the 12-month study. The average patient activation score after 12 months was 8.7 (95% confidence interval, 1.9 to 15.5) points higher in the intervention group than in the usual care group after adjusting for baseline score using linear models with generalized estimating equations. Participants randomized to the intervention had 4.8 (95% confidence interval, 1.4 to 16.7) times the odds of having a final activation level of at least three (“taking action”) than those in the usual care group. Body mass index declined by 1.1 kg/m2 (P=0.01), hemoglobin A1c declined by 0.7% (P=0.01), high-sensitivity C-reactive protein declined by 3.3-fold (P<0.001), and the Short-Form 12 Health Survey mental score increased by five points (P=0.002) in the intervention group relative to usual care.

Conclusions
A home-based intervention improves participants’ activation in their own health and health care, and it may reduce risk factors for CKD in a rural disadvantaged population.
Developing flash media of Quranic-based human reproduction system material
Authors: Kurniawan Arif Didik , Muldayanti Nuri Dewi , Putri Banita Eka 
Published: November 2018

The problem of implementing Islamic values in the learning process is one of the concerns in Islamic-based schools, in particular, Rahmatan Lil’alamin Islamic Senior High School in Pontianak. This study aimed to develop learning media based on the Quran verses in the human reproductive system using Macromedia flash software. This research and development used three phases of the 4D model developed by Thiagarajan, namely define, design, and development. The development results were validated by expert appraisal consisted of instructional review (appropriateness, effectiveness, feasibility) and technical review (media and language). Instruments used in this study were interview guide sheet (define phase), validation sheets, student response questionnaires, and post-test for product trial (development phase). Product trials were carried out by testing large groups consisted of 64 students majoring in social science at Rahmatan Lil’alamin Islamic Senior High School. The expert appraisal results showed that media reached “very valid” criteria with the validation scores 83.33 (instructional review), 80.42 (media), and 85.00 (language). Therefore, the flash media of Quranic-based human reproductive system material is potential to be used as media in teaching Islamic values integrated within the learning process.
FISH MUCUS: A NEGLECTED RESERVOIR FOR ANTIMICROBIAL PEPTIDES
Authors: Hedmon Okella 
Published: November 2018

Antimicrobial resistance has posed a great global burden, with the fear that by 2050 it would have killed more people than cancer if nothing much is done about it. Alongside several attempts in place, zoo-therapy is becoming one of important remedies in the modern society, with hope for solution believed to be hidden in nature. In this study, the authors present a review of journal articles and reports obtained through key word search of several literature databases on recent developments in the battle against the antimicrobial resistance using fish derived antimicrobial peptides. The findings indicate despite some limitations of these antimicrobial peptides, their very broad spectrum activity against pathogens keeps them among promising antibiotics as far as the battle against multidrug resistance is concerned. Much as various methods to study antimicrobial peptides do exist, fish mucus remains less explored. The study recommends aquatic habitat exploration in search for novel bacterial antimicrobial peptides.
FORMULATION DEVELOPMENT OF ACYCLOVIR MICROSPHERE USING NOVEL NATURAL POLYMER
Authors: Singh Priyanka , Lariya Shailendra K 
Published: November 2018

Acyclovir [9-(2-hydroxyethoxymethyl) guanine] is an acyclic nucleoside analogue of guanosine that is a potent and selective antiviral agent. It has a relatively short plasma half-life (3 hr). When orally administered, it is slowly and scarcely absorbed from the gastrointestinal tract. The objective of the present work was to formulate and evaluate microspheres of Acyclovir and produced sustained drug delivery. In these 14 batches of acyclovir microspheres was prepared with using natural polymer Kondagogu gum and other ingredients by solvent evaporation technique. The prepared microspheres were evaluated for different parameters i.e % Drug yield, % drug entrapment, shape, surface morphology, particles size, polydispersity index, zeta potential and in-vitro drug release for 48 hrs in phosphate buffer 7.4. The best batch was performed stability studies for 6 months. The research concluded that Acyclovir microspheres could be an alternative for conventional dosage form and other phytochemical in herbs.
Keywords: Acyclovir, Microspheres, Kondagogu gum, Polydispersity index, in-vitro drug release
A STUDY ON ANXIETY AND DEPRESSION AMONG PATIENTS WITH POLYCYSTIC OVARY SYNDROME
Authors: Radhakrishnan Rahul , Verghese Anna 
Published: November 2018

Background: Patients with polycystic ovarian syndrome (PCOS) often suffer from psychiatric co-morbidities, such as anxiety and depression. The prevalence of PCOS is increasing In India.
Objective: To Study anxiety and depression among PCOS Patients.
Materials and Methods: It was a cross-sectional observational study, which was conducted in Obstetrics and Gynaecology department of a tertiary care hospital. Patients diagnosed with PCOS were assessed on hospital anxiety depression scale and sociodemographic and clinical information was gathered using semi-structured questionnaire.
Result: The prevalence of anxiety of 36% and depression 16% were observed.
Discussion: PCOS patients were found to have high prevalence of anxiety and depression due to the Symptoms of PCOS.
Keywords: Anxiety, PCOS, psychological problems, Depression
MENEROPONG ISTANA TUA (DALAM LOKA) WARISAN ARSITEKTUR TRADISIONAL SUMBAWA (Inheritance on Traditional Architecture of Sumbawa )
Authors: Gambiro Henny , Yamin Ahmad 
Published: November 2018

To look through traditional architecture inheritance of old traditional house Sumbawa palace (Dalam Loka), the former palace of the king of Sumbawa empire. The traditional house is located in Sumbawa City, wester southeast Sumbawa Regency. The architectural shape of old palace as a house on stilts reflects a cultural form in the past. The objective of this paper is to reveal space form, space function, structure and the elements of the house, decoration, and the old palace architecture cosmology. Research method used is descriptive with qualitative approach. Data collection techniques are in the forms of observation, interview, and literature studies. The result shows that the form and function of the old palace building consist of three parts, namely the top, the middle and the bottom. The architecture of that old palace has a philosophy namely Salimpat which describes that all human life aspects would be perfect only if in the form of rectangular. That rectangular philosophy is reflected in the form of land area, the columns, the windows and the room space Warisan arsitektur tradisional Sumbawa rumah adat Istana Tua (Dalam Loka), yang dahulu digunakan sebagai istana Raja Kesultanan Sumbawa. Rumah adat itu berlokasi di Kota Sumbawa, Kabupaten Sumbawa, Nusa Tenggara Barat. Arsitektur rumah adat Istana Tua (Dalam Loka) yang berupa rumah panggung, mencerminkan bentuk kebudayaan masa lampau. Tujuan penulisan ini adalah, mengungkapkan bentuk dan fungsi ruang, struktur dan elemen bangunan, ragam hias, serta kosmologi dalam arsitektur Istana Tua (Dalam Loka). Metode penelitian yang digunakan bersifat deskriptif dengan pendekatan kualitatif. Teknik pengumpulan data berupa wawancara, pengamatan, dan studi pustaka. Hasil penelitian menunjukkan bahwa bentuk dan fungsi bangunan Istana Tua (Dalam Loka), terdiri dari tiga bagian, yaitu bagian atas disebut loteng atau Alang, bagian tengah merupakan badan rumah disebut ruang Dalam Loka (Istana Tua), dan bagian bawah atau kolong yang disebut Tabongan. Arsitektur Dalam Loka menganut falsafah Salimpat yang menggambarkan bahwa segala aspek kehidupan manusia barulah sempurna jika berbentuk segi empat. Falsafah tersebut direfleksikan pada bentuk areal tanah, tiang rumah, jendela dan ruangan.
PENGARUH PERUBAHAN FUNGSI RUANG DAN BENTUK RUMAH-TOKO TERHADAP KARAKTERISTIK ARSITEKTUR CINA DI PECINAN PASAR LAMA TANGERANG
Authors: Januastuti Vicky , Artiningrum Primi 
Published: November 2018

Rumah-Toko merupakan salah satu ciri khas dari Pecinan. Dalam perkembangannya, rumah-toko pada kawasan tersebut mengalami beberapa perubahan fungsi ruang dan perubahan bentuk bangunan rumah-toko akibat dari beberapa faktor, sehingga terlihat karakteristik arsitektur cina pada kawasan tersebut semakin memudar. Pada penelitian sebelumnya belum ada yang mengaitkan antara perubahan dungsi dan bentuk rumah-toko terhadap arsitektur cina. Adapun beberapa penelitian sebelumnya hanya mengaitkan dengan topologi perubahan rumah-toko. Tujuan dari penelitian ini yaitu untuk mengetahui penyebab terjadinya perubahan fungsi pada rumah-toko dan untuk mengetahui pengaruh perubahan fungsi dan bentuk yang menyebabkan mulai pudarnya karakteristik arsitektur cina yang berpengaruh terhadap perubahan karakter arsitektur cina di kawasan pecinan. Metode penelitian ini menggunakan metode kualitatif deskriptif, pengumpulan data-data dari penelitian ini dilakukan dengan cara survei lokasi, wawancara, dan dokumentasi kemudian dianalisis dengan metode deskriptif kualitatif. Setelah dilakukan analisis dari data-data lokasi, maka didapatkan kesimpulan umum bahwa faktor yang mempengaruhi perubahan fungsi dan bentuk yaitu faktor ekonomi, sosial, dan budaya serta fungsi ruang memiliki pengaruh yang lebih kecil terhadap memudarnya karakteristik arsitektur cina dibandingkan dengan perubahan bentuk bangunan yang memiliki pengaruh lebih besar terhadap memudarnya karakteristik arsitektur cina. Shop-House is one of the characteristics of Chinatown. In its development, Shop-House in the region experienced several changes in the function of space and changes in the shape of the houses due to several factors, so that the Chinese architectural characteristics in the area faded. In the previous research, there was no link between changes in function and the form of houses to Chinese architecture. As for some previous studies only linking with the change in the shop-house topology. The purpose of this study is to determine the cause of changes in the function of the Shop-House and to determine the effect of changes in function and shape that cause the fading of Chinese architectural characteristics that affect the changes in Chinese architectural character in Chinatown. This research method uses descriptive qualitative method, the collection of data from this study is done by surveying locations, interviews, and documentation and then analyzed with qualitative descriptive methods. After analyzing the location data, a general conclusion is that the factors that influence changes in function and form are economic, social, and cultural factors and the function of space has a smaller influence on the waning characteristics of Chinese architecture compared to changes in the shape of buildings that have influence. greater to the waning characteristics of Chinese architecture.
Pane in the Glass: A Review of the Accounting Cycle
Authors: Jones Jefferson P. , Long James H. , Stanley Jonathan D. 
Published: November 2018

ABSTRACT
This case employs a realistic scenario in which students apply for internships with Pane in the Glass, Inc.'s financial reporting group. As part of the interview process, students are required to demonstrate their financial accounting knowledge by completing a simulated accounting and financial reporting cycle using Excel. Specifically, they: (1) analyze transactions and prepare the appropriate journal entries, (2) book adjusting and closing journal entries, and (3) prepare a set of financial statements. This case is intended to provide students with a comprehensive review and integration of intermediate financial accounting concepts. The modular nature of the case allows the instructor to assign any number of the case requirements, depending on the desired level of involvement and the amount of time available. In addition, the instructor can easily add, remove, or modify individual transactions, maximizing flexibility and allowing the instructor to tailor the case to specific topics of interest and/or emphasis.
Assessment of Knowledge, Attitude and Breast Self-Examination Practice among Female Students in Sulaimani Polytechnic University
Authors: Masood Mohammed Sarko 
Published: November 2018

Breast cancer is the most common cancer affecting women all over the world. it is estimated to account for around 25% of all malignant in women, and incidence shows continuously increasing trend in many countries all over the world. The aim of the study is to determine level of knowledge, awareness, and BSE practice for breast among SPU female students. A descriptive study was conducted a pre- tested questionnaire was used to determine knowledge, attitude and practices of female students in SPU regarding breast cancer and BSE. The face to face interview questionnaire was filled by systematic random sampling to 216 female students from 4 different colleges belongs to SPU, after getting verbal consent to participate voluntary in the study. Data were entered into Epi-data version 3.1.1 and exported to analyse in SPSS version 17. Descriptive analysis was performed and frequencies and percentages were reported. The mean age of participants was 20.7, the study result shows that the knowledge mean score of participants was 3.95 (SD ± 1.78).181(83.8%) have information of breast cancer, and 157(72.7%) have information on breast cancer sign,136(63.0%) have information on factor that increase change to get breast cancer,150(69.4%)have information on (BSE),86(39.8%)have information how to do (BSE),101(46.8%)have information on mammography .91(42.1%)practice of (BSE), only 10 ( 4.6 %) female students has performing this examination regularly , percentage of students that did not done mammography was 193 (89.4%) . only 2 (0.9 %) performs mammography screening regularly, 18 (8.3 %) have a family member that get breast cancer. Knowledge of female student about breast cancer was at unsatisfactorylevel. Knowledge of female student about S.B.E was also at unsatisfactory level. Poor practice was observed, regarding BSE. Knowledge regarding mammography was also poor.
Sistem Informasi Pengelolaan Zakat Profesi Pada Badan Amil Zakat Nasional (BAZNAS) Kabupaten Bogor
Authors: Indriyani Fintri , Wahyu Abdullah Guntur 
Published: November 2018

Zakat sebagaimana kebutuhan pokok bagi umat islam yang harus dipenuhi agar harta yang dimiliki bersih dan berkah. Zakat profesi merupakan salah satu dari jenis zakat yang wajib dikeluarkan oleh pegawai apabila telah mencapai nishabnya. Badan Amil Zakat Nasional Kab. Bogor adalah lembaga yang mengelola zakat bagi masyarakat Bogor yang saat ini masih menerima secara langsung dana dari para muzakki dan petugas masih melakukan pencatatan secara manual sehingga data yang ada menumpuk dan kurang terorganisir dengan baik, selain itu para muzaki harus menyempatkan waktunya untuk melakukan kewajibannya berzakat. Sistem Informasi pengelolaan zakat profesi ini dibuat dengan metode waterfall dan pengujian web menggunakan metode blackbox testing. Pembuatan system informasi ini bertujuan agar memudahkan muzaki dan pengelola serta meningkatkan kepercayaan mereka terhadap BAZNAS. Dengan penerapan system informasi ini muzaki menjadi mudah untuk menyalurkan zakat profesinya, dan menambah kepercayaan karena adanya transparansi dari laporan penyaluran zakat.
Pemilihan Jasa Pengiriman Terbaik Menggunakan Metode Simple Additive Weighting (SAW)
Authors: Oktaviani Nia , Merlina Nita , Nurmalasari Nurmalasari 
Published: November 2018

Meningkatnya pengguna internet membuat semakin meningkat pula pembelian barang secara online. Baik pembeli, maupun penjual yang menggunakan transaksi secara online dalam pengiriman barangnya dapat menggunakan 2 metode pengiriman barang, yaitu bertemu secara langsung, atau mengunakan jasa pengiriman barang. Dan sebagai pengguna online shop juga pastinya akan sangat bingung dan kesulitan dalam memilih jasa pengiriman barang sehingga mempertimbangkan faktor lain dalam memilih jasa pengiriman barang. Mulai dari harga, pengemasan barang, lama pengiriman barang, banyaknya cabang, layanan sistem hingga pelayanan membuat pengguna online shop bingung dalam memilih jasa pengiriman barang terbaik sesuai kebutuhan pengguna. Oleh karena itu pada penelitian ini akan diangkat suatu kasus yaitu mencari jenis pengiriman terbaik berdasarkan kriteria-kriteria yang telah ditentukan dengan menggunakan metode Simple Additive Weighting (SAW) untuk melakukan perhitungan pada kasus pemilihan jenis barang terbaik.
Abordajes en la evaluación del desarrollo infantil temprano
Authors: Pacheco Claudia , Aquino  Sánchez Blanca , Elías Rodolfo 
Published: November 2018

El presente artículo realiza un análisis de los abordajes utilizados en la evaluación del desarrollo infantil temprano. En primer término, se presentan diferentes abordajes y conceptos respecto a la evaluación y al conocimiento que genera. Posteriormente se discute el concepto de calidad en el desarrollo temprano y la calidad en la intervención educativa en la primera infancia. Luego se realiza una reseña de los niveles de análisis de la realidad y los alcances de la evaluación. Finalmente, se aborda el tema central del artículo que consiste en los diferentes enfoques utilizados en la evaluación del desarrollo en la primera infancia, en sus diferentes etapas. El artículo concluye señalando que evaluar el desarrollo infantil es una tarea que implica un análisis multidimensional. Se señala la importancia de la evaluación en el desarrollo infantil temprano de tal forma a que los programas y servicios dirigidos a esta población logren los resultados esperados y permitan que niños o niñas alcancen los niveles de desarrollo en diferentes dominios necesarios para su aprendizaje a lo largo de la vida.
Pengembangan Perangkat Pembelajaran Fisika Berbasis Inkuiri Terbimbing Berbantuan Eksperimen Untuk Meningkatkan Penguasaan Konsep Siswa
Authors: Wahyuni Sri , Kosim Kosim , Gunawan Gunawan 
Published: November 2018

The study aims to develop physics learning device based guided inquiry with experiments that valid, practical, and effective to improve studentsÃ¢â¬â¢ mastery concept. The research stages refers to Borg & Gall's model from preliminary studies to main field testing. The validity data is obtained from the assessment for the feasibility of learning devices by experts, then analysed to determine the level of validity. Expert advice is used to revise the learning device. Learning device was implementation to test the practicality and effectiveness of learning device to improve students' mastery concept. The results of the study show that learning device are very valid category. Result of the trial based on the data of learning implementation show that learning device are in the practical category.ÃÂ Guided inquiry model with an experiment in learning physics effective to improve studentsÃ¢â¬â¢ mastery concept. Increased students mastery concept on cognitive aspect remembering (C1), understanding (C2), applying (C3) and create (C6) in high categories, while the cognitive aspect analyzing (C4) and evaluating (C5) in the medium category.
Особливості показників імунітету у хворих на непроліферативні форми хронічного гломерулонефриту
Authors: Driianska V. , M. Velychko M. , Petrina O. , Poroshina T. , Nepomnyaschiy V. , Liksunova L. , Malashevska N. 
Published: November 2018

Мета роботи: визначити особливості HLA-фенотипів та показників цитокінової ланки імунітету з факторами ендотеліальної дисфункції у хворих на непроліферативні (НП) форми хронічного гломерулонефриту (ХГН) з нефротичним синдромом (НС).
Матеріал та методи. Вивчали розподіл HLA-антигенів за допомогою мікролімфоцитотоксичного тесту Терасакі у 264 хворих на ХГН, НС (серед яких аналізували дані 96 з НП ГН) та 350 здорових донорів. Морфологічний діагноз був підтверджений методом тонкоігольної нефробіопсії. Для вивчення рівнів цитокінів та факторів ендотеліальної дисфункції в крові 110 пацієнтів використовували імуноферментний аналіз.
Результати. Для ХГН, НС відносний ризик високий (RR> 2)за наявності HLA-А23, 24, 28, В8, 38, 41, 44 (у хворих на НП ГН +А30),причинна роль (σ> 0.1)показана для А24, 28, В8 (НП +A19+31+32); протекторами захворювання є В12 та В16 (НП +А9). Виявлені антигени-провокатори різних морфологічних форм ХГН.
У пацієнтів з НП ГН виявлено в крові високі рівні як про- (трансформуючий фактор росту альфа (TNF-α), інтерлейкіну 17 (IL-17), моноцитарний хемоатрактантний протеїн 1 (МСР-1)), так і протизапальних (IL-4, трансформуючий фактор росту бета (TGF-β)) цитокінів, факторів ендотеліальної дисфункції (фактор росту ендотелію судин (VEGF), розчинна молекула адгезії судинних клітин (sVCAM-1)) та зниження Е-селектину. РівеньMCP-1 у хворих на проліферативні ГН був вищим, ніж у разі непроліферативних форм.
Не виявлено достовірних змін цих показників імунітету в групі хворих на НП ГН після проведеного лікування, за винятком зниження TNF-α (р = 0,001), але позитивний ефект лікування асоціював з достовірним зниженням концентрацій МСР-1 (р = 0,005) і VEGF (р = 0,028).
Висновки. Виявлені достовірні асоціаціїHLA з ХГН, НС та його непроліферативними морфологічними формами дозволяють вважати такі антигени в фенотипі пацієнтів та інші показники імунітету ((TNF-α,MCP-1 і VEGF) додатковими прогностичними маркерами.