bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dislocation and Snaring of an Aortic Bifurcation Stent During Transfemoral Aortic Valve Replacement—a Case Report
Authors: Meledeth Christy , Lambert Thomas 
Published: November 2024

ABSTRACTTransfemoral aortic valve replacement (TAVR) is an effective way to treat severe aortic valve stenosis, especially in patients who are high‐risk for surgery. Dislocation of an endoluminal aortic bifurcation stent graft during TAVR is an extremely rare complication. We present a case on how management of this complication was successfully done.An 86‐year‐old man presented at the ER after syncope. He was admitted to the cardiology department for further examinations. Transthoracic echocardiography (TTE) revealed severe aortic stenosis. Other comorbidities included endovascular stent graft repair due to an infrarenal abdominal penetrating aortic ulcer. During the following TAVR procedure dislocation of the endoluminal stent graft was observed. Using a snare loop this foreign material was fixated in the right common iliac artery. The patient was hemodynamically stable and endoluminal aortic valve replacement could successfully commence. After implantation of aortic valve bioprothesis, the foreign material was retrieved from the right femoral artery. The patient remained asymptomatic and stable postprocedural.Dislocation of an endoluminal stent graft during TAVR remains a rare complication. This complication can arise due to several factors, including patient‐specific anatomical challenges and procedural complexities. Decisions are based on the individual patient but are also made in consensus with the interventional cardiologist' team.
Prostatic duct adenocarcinoma—A challenging variant of prostate cancer in a low‐resource setting
Authors: Okidi Ronald , Hajarah Nakazibwe , Mukurasi Derrick , Obonyo Emmanuel , Makai Emmanuel , Lajul Daniel , Odongkara Moses , Bamutorana Tracy , Omagino BridgetRose Aguti , Okello Isaac 
Published: November 2024

Key Clinical MessageThis case emphasizes the challenges in diagnosing and treating Prostatic Duct Adenocarcinoma, especially in resource‐limited settings. Early and accurate diagnosis is crucial for better patient outcomes, but limited access to advanced diagnostics and specialized treatments significantly hinders the effective management of this aggressive form of prostate cancer.
C─C Coupling of Methylene Ketones with Alcohols Enabled by Fe‐Catalysis: Access to Substituted Pyrroles and Pharmaceuticals
Authors: Bera Atanu , Purushotam  , Kabadwal Lalit Mohan , Banerjee Debasis 
Published: November 2024

AbstractHerein, we have reported a sustainable and chemo‐selective strategy for the synthesis of functionalized branched alcohols. A commercially available catalytic system does not need any special ligand and liberated water and hydrogen as side products. A series of alkyl primary alcohols (C4–C10), including methanol, were tolerated in good to high yield. Sequential transformations to substituted pyrroles, chromenes and synthesis of donepezil drug were obtained (>57 entries). Preliminary mechanistic investigations were performed to understand the catalytic pathways.
Enhanced Electrochemical Performance of Copper(II) Metal Organic Framework‐Ternary Quantum Dots Composite towards the Detection of Bisphenol A
Authors: Oloyede Solomon O. , Ajibade Peter A. 
Published: November 2024

AbstractTernary quantum dot metal organic framework (MOFs) composite sensor formulated as (ZnInSe2@[Cu(2‐HNA)2(H2O)]) with an enhanced electrochemical performance was synthesized from a copper(II) metal‐organic framework complex ([Cu(2‐HNA)2(H2O)]) and ZnInSe2 ternary quantum dot (TQDs). The compounds were characterized by Fourier transform infrared spectroscopy, Ultraviolet‐Visible spectroscopy, transmission electron microscopy, scanning electron microscopy, single crystal X‐ray crystallography, and photoluminescence. Molecular structure of the copper(II) complex revealed a distorted square pyramidal geometry with two molecules of 2‐hydroxy‐1‐naphthaldedyde at the basal planes as bidentate chelating ligands with a coordinated water molecule at the apical position. TEM micrographs revealed monodispersed composite with an average particle size of 3.2 nm. The composite and its precursors were used as ectrochemical sensor for the detection of bisphenol A, using cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. The composite modified on a gold electrode exhibited enhanced electrochemical performance in comparison to those of the MOFs and TQDs. The reaction process at the surface of the modified electrode with the composite is diffusion controlled with a limit of detection, and limit of quantitation of 4.70 nM and 14.26 nM over a concentration range of 10–50 nM (S/N=3). The gold modified composite electrode is stable and could serve as a model for the development of electrochemical sensor to determine BPA.
Tuning Tetramethoxy‐acridiniums for Fluorophores and Organic Photoredox Catalysis
Authors: Nowack Marko H. , Johansen Magnus B. , Sams Søren , Hillers‐Bendtsen Andreas E. , Mikkelsen Kurt V. , Laursen Bo W. 
Published: November 2024

AbstractTetramethoxy substituted alkyl‐acridiniums (TMAcr+) are readily available by facile nucleophilic aromatic substitution on tris(2,6‐dimethoxyphenyl)carbenium, but are non‐fluorescent, presumably due to intramolecular photoinduced electron transfer quenching. In this work we introduce electron withdrawing groups by electrophilic aromatic substitution reactions, leading to fluorescence turn‐on. The acridiniums are moderately fluorescent (φf=20 %) with long fluorescene lifetimes (τf=9 ns). The positive excited state reduction potentials (E*red=+1.6 V) make the TMAcr+ excellent electron acceptors in the excited state, and efficient reductive photoredox catalysts able to oxidize a broad range of substrates.
Potassium Phosphate‐Mediated Synthesis of C4‐Phosphorylated Quinolines via Cascade Cycloisomerization of Ynones
Authors: Qiu Yi‐Feng , Li Jin‐Hao , Wang Qiang , Li Ming , Quan Zheng‐Jun , Wang Xi‐Cun , Liang Yong‐Min 
Published: November 2024

AbstractA cascade phosphorylation cycloisomerization of readily accessible ynones and diphenylphosphine oxides facilitated by potassium phosphate is described, allowing for the straightforward synthesis of C4‐phosphorylated quinoline scaffolds. The formation of a C−P bond and a C−N bond is achieved in a single procedure without the need for pre‐assembled quinoline cores prior to phosphorylation. This transformation operates without the requirement for metals or oxidants and exhibits excellent compatibility with various functional groups. Furthermore, antimicrobial activity evaluation demonstrated that the synthesized C4‐phosphorylated quinoline derivatives exhibited potent inhibitory activity against Staphylococcus aureus.
Role of Active Centers in Predicting the Catalyst Turnover: A Theoretical Study
Authors: Bhattacharyya Himangshu Pratim , Sarma Manabendra 
Published: November 2024

AbstractWater oxidation catalysis has garnered significant attention due to its potential for sustainable energy conversion. Among molecular catalysts, [Fe(OTf)2(
Pytacn)] complexes have exhibited notable turning‐over rates. Although various [M(OTf)2(
Pytacn)] complexes (M=Mn, Co, Ni) have been synthesized, however, the role of active centres has not been thoroughly investigated. In this study, we apply our newly developed catalytic models, efficiency conceptualization model (ECM) and the maximum kinetic efficiency MaxKinEff framework to assess the role of the active centres in its catalytic performance. Our computational analysis identifies cobalt‐based [Co(OTf)2(
Pytacn)] as a superior alternative for water oxidation reactions. Notably, cobalt catalysts exhibit a longer lifespan (∼44 days) and higher turnover numbers (TON), with computed values of
(ECM)=3.30 h−1,
(ECM)=3456,
(MaxKinEff)=12.43 h−1, and
(MaxKinEff)=3616. These findings suggest that cobalt could play a pivotal role in improving the efficiency of molecular catalysts for water oxidation.
Comparing de novo chronic myeloid leukemia in blastic phase with Philadelphia chromosome–positive acute lymphoblastic leukemia after allogeneic hematopoietic cell transplantation
Authors: Okada Yosuke , Tachi Noriaki , Shimazu Yutaka , Murata Makoto , Nishiwaki Satoshi , Onishi Yasushi , Jinguji Atsushi , Uchida Naoyuki , Tanaka Masatsugu , Hasegawa Yuta , Ito Ayumu , Kako Shinichi , Nishida Tetsuya , Onodera Koichi , Sawa Masashi , Nakamae Hirohisa , Toyosaki Masako , Kanda Yoshinobu , Onizuka Makoto , Fukuda Takahiro , Ohbiki Marie , Atsuta Yoshiko , Arai Yasuyuki , Tachibana Takayoshi 
Published: November 2024

AbstractBackgroundDe novo chronic myeloid leukemia in blastic phase (CML‐BP) showing lymphoid immunophenotype mimics Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph‐positive ALL). Although upfront allogeneic hematopoietic cell transplantation (HCT) is considered in both diseases, it is not yet clear whether the transplant outcomes are also similar.MethodsUsing a registry database, the transplant outcomes between de novo CML‐BP and Ph‐positive ALL in negative‐minimal residual disease (MRD), positive MRD, and nonremission cohorts were compared, respectively. All of the included patients had received tyrosine kinase inhibitor therapy before HCT and underwent HCT between 2002 and 2021. Regarding Ph‐positive ALL, patients with p210 transcripts were excluded because there was concern that this group might include patients with de novo CML‐BP.ResultsAlthough most of the outcomes were comparable, in patients with positive MRD at HCT, de novo CML‐BP was significantly associated with superior disease‐free survival (DFS) (hazard ratio [HR] 0.6, p = .0032), overall survival (HR 0.66, p = .027), and a lower risk of relapse (HR 0.48, p = .0051). In subgroup analyses, BCR::ABL1 mutation status had a significant interaction with the disease (p for interaction = .0027). De novo CML‐BP seemed to be associated with superior disease‐free survival in a BCR::ABL1 mutation‐positive cohort, whereas this association was not observed in a mutation‐negative cohort.ConclusionsConsidering previous reports that showed inferior outcomes for de novo CML‐BP compared to Ph‐positive ALL, the data suggested that allogeneic HCT could overcome the poor prognosis of de novo CML‐BP. These findings highlight the importance of distinguishing de novo CML‐BP from Ph‐positive ALL.
Metal–Metal Bonding in Tri‐Actinide Clusters: A DFT Study of [An3Cl6]z (z=1–6) and [An3Cl6Cp3]z (z=−2–+3; An=Ac, Th, Pa, U, Np, Pu)
Authors: Tomeček Josef , Liddle Stephen T. , Kaltsoyannis Nikolas 
Published: November 2024

AbstractThe actinide–actinide bonding in tri‐actinide clusters [An₃Cl₆]z (An=Ac–Pu, z=1–6) and [An₃Cl₆Cp₃]z (z=−2–+3; Cp=(η5‐C5H5)) is studied using density functional theory. We find 3‐centre bonding similar to the tri‐thorium cluster [{Th(η⁸‐C₈H₈)(μ₃‐Cl)₂}₃{K(THF)₂}₂]∞, as we previously reported (Nature 2021, 598, 72–75). The population of 3‐centre molecular orbitals (3c‐MOs) by zero, one or two electrons correlates with shortening of the An−An bond lengths, which also decrease with increasing actinide atomic number, consistent with the contraction of the actinide valence atomic orbitals. Mulliken analyses indicate that these 3c‐MOs predominantly involve An 6d and 5 f orbitals. Various methods evidence the presence of An−An bonding in most systems with populated 3c‐MOs, including bond orders (Mayer and Wiberg), quantum theory of atoms in molecules metrics (ρ, ∇2ρ, −G/V, H, delocalization indices), electron localization function, and electron density assessments. Additionally, we explore the effect of Cp ligand substitution on uranium complexes, finding that bulkier Cp ligands can induce U−U bond distortions and result in slightly longer U−U bonds. Overall, this study advances our understanding of metal–metal bonding in tri‐actinide clusters, highlighting its effects on geometric and electronic structures.
Efficacy of Mindfulness Meditation on Patients With Stroke With Concurrent Coronary Heart Disease: A Randomised Controlled Trial
Authors: Kou Lulu , Liu Min , Kang Shaowei , Ni Guangxiao 
Published: November 2024

ABSTRACTObjectiveThis study aimed to investigate the efficacy of mindfulness meditation on sleep quality and negative emotions in patients with stroke with concurrent coronary heart disease.MethodsThis study was a randomised controlled trial. A total of 72 patients with stroke with concurrent coronary heart disease were randomly divided into an observation group and a control group, with 36 patients in each group. The control group received routine treatment plus eszopiclone tablets at a dosage of 3 mg once daily. The observation group received mindfulness meditation in addition to the treatment given to the control group. The Pittsburgh Sleep Quality Index was used to assess sleep status, the Self‐Rating Anxiety Scale and Self‐Rating Depression Scale were used to assess depression and anxiety, and the Fugl–Meyer Assessment was used to assess motor function. All participants in both groups received a 6‐week intervention.ResultsPairwise comparisons revealed that the observation group had better outcomes in sleep quality, sleep onset latency, sleep duration, sleep efficiency, sleep disturbances, daytime function and total scores at both 6 and 12 weeks compared with the control group (p < 0.05). After 12 weeks of intervention, compared with the control group, the total score of sleep quality improved more significantly (9.22 ± 2.35/6.26 ± 2.47). Additionally, different treatment methods had varying effects on anxiety scores, depression scores and motor function scores between the two groups (p < 0.001). Further comparisons showed that the observation group had lower anxiety and depression scores and higher motor function scores at both 6 and 12 weeks compared with the control group (p < 0.05).ConclusionMindfulness meditation can effectively improve sleep quality and reduce negative emotions in patients with stroke with concurrent coronary heart disease, as well as promote the recovery of limb functions.
Management of Soft Tissue Defects Around Single Implants: A Systematic Review of the Literature
Authors: Moussa Haithem , Nasri Wafa , Gargouri Rania , Bouslema Afif 
Published: November 2024

ABSTRACTObjectivesThe aim of this systematic review was to assess the effectiveness of the available techniques for the management of peri‐implant soft tissue defects around single implants in the anterior region.Material and MethodsA comprehensive search was conducted in PubMed (MEDLINE), Web of Science (all databases), and Cochrane, using keywords and MeSH terms related to the topic. This systematic review included prospective interventional studies with a minimum of 10 patients and at least 6 months of follow‐up.ResultsA total of 13 articles were included, with eight focusing on outcomes related to buccal soft tissue dehiscence coverage procedures and the remaining five investigating interventions aimed at augmenting soft tissue thickness. Coronally advanced flap in combination with connective tissue graft was the most effective technique for buccal soft tissue dehiscence coverage in the medium and long term. In terms of increasing soft tissue thickness, both connective tissue graft and acellular dermal matrix demonstrated satisfactory short‐term outcomes; however, their long‐term efficacy remains unclear.ConclusionsSoft tissue augmentation procedures resulted in satisfactory outcomes, in terms of buccal soft tissue dehiscence coverage and soft tissue thickness increase, around single implants in the esthetic area. Peri‐implant plastic surgery has improved both the esthetic appearance and quality of life of patients.PROSPERO Registration CodeCRD42023398424
Effects of Toothpaste Containing 2% Zinc Citrate on Gingival Health and Three Related Bacteria—A Randomized Double‐Blind Study
Authors: Zhou Yujie , Zhou Yi , Liao Binyou , Chen Xiaobin , Niu Yulong , Ren Biao 
Published: November 2024

ABSTRACTObjectivesGingivitis is the initial stage of periodontitis, one of the most common oral diseases and the primary cause of tooth loss. This study aims to evaluate the effect of toothpaste containing 2% zinc citrate on gingival health and the abundance of three bacteria related to gingivitis and periodontitis.Methods and MaterialsEleven volunteers with the same oral health status were randomly assigned to the treatment (n = 5) and control (n = 6) groups. The control group used fluoride toothpaste, while the treatment group used fluoride toothpaste supplemented with 2% zinc citrate for 3 months. The plaque index, gingival index, and bleeding index were measured at baseline (0 day), 3 weeks, and 3 months. Dental plaque from four areas of the mouth (FDI criteria) was collected at the same timepoints. A total of 132 dental plaque samples were analyzed using quantitative PCR (qPCR) to monitor the abundance of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis, and Tannerella forsythia.ResultsToothpaste containing 2% zinc citrate significantly lowered the gingival index and reduced gum bleeding but did not affect the plaque index. It also reduced the total abundance of the three bacteria related to gingivitis and periodontitis in dental plaque over a long‐term period.ConclusionsToothpaste with 2% zinc citrate persistently improves gingival health and reduces the presence of gingivitis‐associated bacteria in dental plaque.Trial RegistrationChinese Clinical Trial Registry (Clinical trial registration no.: ChiCTR1900020592) (09/01/2019).
Investigating multi‐trophic effects of St. Augustinegrass cultivar blends in the Southeastern United States
Authors: Pinkney James Louis , Iannone Basil V. , Milla‐Lewis Susana , van der Laat R. , Unruh J. Bryan , Schiavon Marco , Dale Adam G. 
Published: November 2024

AbstractWarm‐season turfgrasses, including St. Augustinegrass [Stenotaphrum secundatum (Walt.) Kuntze], are produced and installed as monocultures of single cultivars. Recent research indicates that blending St. Augustinegrass cultivars can increase turfgrass stand resilience to insect pests, establishment of undesired plant species, and abiotic stressors without reducing plant performance. However, effects on specific key turfgrass insect pests are less documented and the mechanisms driving changes in turfgrass stand resilience are unclear. Moreover, it remains unknown if the effects of cultivar blends on biotic resistance vary across St. Augustinegrass’ range. Here, we pair a regional common garden observational field study with a controlled greenhouse experiment to isolate the effects of cultivar blends on the recruitment of predatory arthropods (top‐down pest regulation) and on southern chinch bug [Blissus insularis Barber] performance (bottom‐up pest regulation). We find that cultivar diversity has no effect on natural enemy recruitment but natural enemies do vary predictably with changes in geographic location. In contrast to our hypothesis, southern chinch bug reached higher densities in cultivar blends compared to cultivar monocultures, although this effect was driven by specific cultivar blends. Despite higher pest densities in turfgrass blends on average, blends of four St. Augustinegrass cultivars maintained a higher percent green cover than cultivar monocultures, suggesting that cultivar blends can persist longer under elevated pest densities compared to cultivar monocultures. Our findings can guide future research focused on blending warm‐season turfgrass cultivars as an integrated pest management strategy for more resilient and sustainable turfgrass lawns.
Application of Hydroxyaromatic Aldehydes in Ultra‐Efficient and Metal‐Free Photocatalytic E→Z Isomerization of Olefin
Authors: Liu Chun‐Xiu , Yao Yao , Zhou Zi‐Wen , Qin Song , Yu Zhi‐Peng , Tao Fei‐Yan , Li Wen‐Dian , Yu Xiao‐Qi , Wang Na 
Published: November 2024

AbstractThe strategy of photocatalyzed E→Z isomerization of olefins to access thermodynamically less stable Z‐alkenes has recently received considerable attention. Here, we have discovered a sensitizer of hydroxyaromatic aldehyde that can rapidly achieve olefin E→Z isomerization under blue light irradiation. Notably, 2‐hydroxybenzene‐1,3,5‐tricarbaldehyde, when assisted by blue light, can achieve efficient and selective conversion within just 5 minutes (Z/E=92 : 8). The reaction can be successfully scaled up to gram scale, and exhibits remarkable reactivity toward various derivatives of ethyl cinnamate (27 examples) and other olefins. Furthermore, the former can be directly cyclized by a hydroxyl derivative to produce 4‐substituted coumarin. The prominent preponderance of this method includes being metal‐free, efficient, convenient, no by‐products and achieving high selectivity. Correlation of sensitizer triplet energy (ET) and preliminary mechanistic experiments indicate that the accomplishment of this reaction is based on the selective excitation mechanism.
Z‐Scheme Enabled 1D/2D Nanocomposite of ZnO Nanorods and Functionalized g‐C3 N4 Nanosheets for Sustainable Degradation of Terephthalic Acid
Authors: Mittal Honey , Kumar Arun , Sharma Diksha , Khanuja Manika 
Published: November 2024

AbstractThe urgent need to mitigate water pollution and achieve Sustainable Development Goal 14 (SDG 14)‐Life below water, necessitates developing efficient and eco‐friendly wastewater treatment technologies. This research addresses this challenge by photocatalytic degradation of terephthalic acid, a precursor for PET bottles using environment‐friendly and biocompatible photocatalysts. The 1D/2D nanocomposite comprising zinc oxide (ZnO) nanorods and functionalized graphitic carbon nitride (Zn‐TG) nanosheets were synthesized and thoroughly characterized. The nanocomposite effectively mitigated the individual drawbacks of Zn‐TG agglomeration and the wide band gap of ZnO as confirmed through zeta potential and Tauc′s plot studies, respectively. The synthesized nanocomposite achieved ~100 % degradation within 60 minutes, exhibiting superior kinetics (~2.5 times) compared to pristine samples. The enhanced degradation efficiency was elucidated by efficient charge carrier transfer (~5 times faster) and separation (~2 times improved) as confirmed through electrochemical impedance spectroscopy and time‐resolved photoluminescence studies. The proposed Z‐scheme pathway provides mechanistic insights. This proposed mechanism is supported by extensive electron paramagnetic resonance (EPR) and scavenger studies. The liquid chromatography‐mass spectrometry (LC–MS) analysis confirms the formation of less toxic byproducts for ensuring that the wastewater treatment process is efficient and environmentally friendly. This research helps in developing a highly effective and sustainable wastewater treatment technology.