bluuebunny/crossref_metadata_2025_split huggingface dataset:
La place du sadomasochisme lesbien : construction et vivabilité des plaisirs dans une nouvelle de Jane Delynn
Authors: Wadbled Nathanaël 
Published: May 2018

Dans « The duchess of LA », J. Delynn propose le récit d’une initiation à la sexualité sadomasochiste lesbienne. Elle l’oppose à une sexualité sadomasochiste hétérosexuelle en la décrivant dans un espace différent de l’espace domestique conjugal. Dans ce dernier, le plaisir est la réalisation d’un désir préalablement déterminé par lequel le sujet définit à la fois son identité et la conscience de lui-même. Dans un club sadomasochiste lesbien au contraire, le plaisir est une jouissance qui survient en excès par rapport à la conscience que le sujet a de lui-même. La conscience du désir est alors produite performativement. Il s’agit d’un côté de comprendre ce qui produit un orgasme, et d’un autre côté de le vivre.
Evaluation of the Impact of a Chronic Total Coronary Occlusion on Ventricular Arrhythmias and Long‐Term Mortality in Patients With Ischemic Cardiomyopathy and an Implantable Cardioverter‐Defibrillator (the eCTOpy‐in‐ICD Study)
Authors: van Dongen Ivo M. , Yilmaz Dilek , Elias Joëlle , Claessen Bimmer E. P. M. , Delewi Ronak , Knops Reinoud E. , Wilde Arthur A. M. , van Erven Lieselot , Schalij Martin J. , Henriques José P. S. 
Published: May 2018

Background

Previous studies report conflicting results about a higher incidence of ventricular arrhythmias in patients with a chronic total coronary occlusion (
CTO
). We aimed to investigate this association in a large cohort of implantable cardioverter defibrillator patients with long‐term follow‐up.

Methods and Results

All consecutive patients from 1992 onwards who underwent implantable cardioverter defibrillator implantation for ischemic cardiomyopathy at the Leiden University Medical Center were evaluated. Coronary angiograms were reviewed for the presence of a
CTO
. The occurrence of ventricular arrhythmias and survival status at follow‐up were compared between patients with and patients without a
CTO
. A total of 722 patients constitute the study cohort (age 66±11 years; 84% males; 74% primary prevention, median left ventricular ejection fraction 30% [first–third quartile: 25–37], 44% received a cardiac resynchronization therapy defibrillator). At baseline, 240 patients (33%) had a
CTO
, and the
CTO
s were present for at least 44 (2–127) months. The median follow‐up duration was 4 (2–6) years. On long‐term follow‐up,
CTO
patients had a higher crude appropriate device therapy rate (37% versus 27%,
P
=0.010) and a lower crude survival rate (51% versus 67%,
P
<0.001) compared with patients without a
CTO
. Corrected for baseline characteristics including left ventricular ejection fraction, the presence of a
CTO
was an independent predictor for appropriate device therapy.

Conclusions

The presence of a
CTO
in implantable cardioverter defibrillator patients was associated with more appropriate device therapy and worse prognosis at long‐term follow‐up. Further investigation is warranted regarding a potential beneficial effect of
CTO
revascularization on the incidence of ventricular arrhythmias.
Online insomnia treatment and the reduction of anxiety symptoms as a secondary outcome in a randomised controlled trial: The role of cognitive-behavioural factors
Authors: Gosling John A , Batterham Phil , Ritterband Lee , Glozier Nick , Thorndike Frances , Griffiths Kathleen M , Mackinnon Andrew , Christensen Helen M 
Published: May 2018

Objective: Insomnia and anxiety commonly co-occur, yet the mechanisms underlying this remain unclear. The current paper describes the impact of an Internet-based intervention for insomnia on anxiety, and explores the influence of two cognitive-behavioural constructs – dysfunctional beliefs about sleep and sleep-threat monitoring. Methods: A large-scale, 9-week, two-arm randomised controlled trial ( N = 1149) of community-dwelling Australian adults with insomnia and elevated yet subclinical depression symptoms was conducted, comparing a cognitive behavioural therapy–based online intervention for insomnia (Sleep Healthy Using The Internet) with an attention-matched online control intervention (HealthWatch). Symptoms of anxiety were assessed at pretest, posttest, and 6-month follow-up. Dysfunctional beliefs about sleep and sleep threat monitoring were assessed only at pretest. Results: Sleep Healthy Using The Internet led to a greater reduction in anxiety symptoms at both posttest ( t724.27 = –6.77, p < 0.001) and at 6-month follow-up ( t700.67 = –4.27, p < 0.001) than HealthWatch. At posttest and follow-up, this effect was found to moderated by sleep-threat monitoring ( t713.69 = –2.39, p < 0.05 and t694.77 = –2.98, p < 0.01 respectively) but not by dysfunctional beliefs about sleep at either posttest or follow-up ( t717.53 = –0.61, p = 0.55 and t683.79 = 0.22, p = 0.83 respectively). Participants in the Sleep Healthy Using The Internet condition with higher levels of sleep-threat monitoring showed a greater reduction in anxiety than those with lower levels from pretest to posttest, ( t724.27 = –6.77, p < 0.001) and through to 6-month follow-up ( t700.67 = –4.27, p < 0.001). This result remained after controlling for baseline anxiety levels. Conclusion: The findings suggest that online cognitive behavioral therapy interventions for insomnia are beneficial for reducing anxiety regardless of people’s beliefs about their sleep and insomnia, and this is particularly the case for those with high sleep-threat monitoring. This study also provides further evidence for cognitive models of insomnia.
Innovation and inter-organizational learning in the context of public service reform
Authors: Hartley Jean , Rashman Lyndsay 
Published: May 2018

This article examines links between innovation and inter-organizational learning in the context of public service reform. The theory-building and empirical research draws on longitudinal analysis using mixed methods and multiple stakeholder respondents, set in the context of the Beacon Scheme, an instrument of UK public service reform. The research examines two questions: first, how does inter-organizational learning contribute to innovation? Second, how do changes in the approach to inter-organizational learning shape changes in the approach to innovation over time? The research on the whole of English local government ( N = 388) used temporal bracketing to examine developments in three phases over nine years. The article builds theory about the inter-organizational learning underpinning innovation, and shows that the approach to innovation changed over time, shifting from learning to imitate, to learning to innovate. Points for practitioners • Innovation is underpinned by inter-organizational learning. • Organizations improved over time in their ability to acquire and use learning. • Innovation involves the sharing of tacit as well as explicit knowledge. • Over time, organizations learnt to shift from learning to imitate, to learning to innovate. • Improvement through inter-organizational learning was not uniform. Initially, differences between organizations widened as those able to acquire learning used it to improve more rapidly. • Adaptation to local context, not adoption of a single approach, is apparent but is underemphasized in public service reform. • Learning pull, not dissemination push, aids learning and improvement.
Between Academia and Politics: Latin American Studies in Germany during the Cold War
Authors: Puhle Hans-Jürgen 
Published: May 2018

Latin American studies in Germany from the 1960s on developed in two waves with (partial) crises and periods of stagnation in between. Whereas in the communist GDR they were affected by the limited scope of academic endeavors and their instrumentalization for state and party politics and policies, in the Federal Republic interdisciplinary Latin American studies had two tiers (within the universities and outside as independent research institutes) and were shaped by the particular structure of funding schemes and agencies and by “triggers” such as the Cuban Revolution, the Chilean coup, the arrival of exiles, and the presence of the Latin American revolutionary experience in the debates of the West German student movement after 1968. While many of the West German features were shared with other Western countries, significant differences emerged because of Germany’s short colonial tradition, the Cold War rivalry between the Federal Republic and the GDR, and the fact that political foundations such as the Konrad Adenauer Foundation and the Friedrich Ebert Foundation played a key role not only in designing and implementing government-financed development aid projects in Latin America but also in helping to promote and shape a new takeoff for Latin American studies (a uniquely German constellation). A partir de la década de 1960, los estudios alemanes sobre Latinoamérica se desarrollaron en dos oleadas, con crisis (parciales) y períodos de estancamiento en el proceso. En la RDA comunista, la investigación se vio afectada por el alcance limitado de los esfuerzos académicos y su instrumentalización para políticas estatales y partidarias. En la República Federal, los estudios interdisciplinarios latinoamericanos se desarrollaron en dos ámbitos (universidades además de lugares externos como institutos de investigación independientes) y obedeciendo a estructuras y agencias de financiamiento particulares, así como “factores detonantes” (por ejemplo, la Revolución Cubana, el golpe de estado en Chile, la llegada de exiliados y la presencia de la experiencia revolucionaria latinoamericana en los debates del movimiento estudiantil de Alemania Occidental después de 1968). Mientras que muchas de las características de la República Federal eran compartidas por otros países occidentales, surgieron diferencias significativas a partir de la corta tradición colonial alemana, la rivalidad entre la República Federal y la RDA durante la Guerra Fría, y el hecho de que patronatos políticos como la Fundación Konrad Adenauer y la Fundación Friedrich Ebert desempeñaron un papel clave no solo en el diseño e implementación de proyectos gubernamentales de ayuda al desarrollo en Latinoamérica, sino también en promover y encaminar los estudios latinoamericanos (en una constelación exclusivamente alemana).
Factors Associated With Psychological Readiness to Return to Sport After Anterior Cruciate Ligament Reconstruction Surgery
Authors: Webster Kate E. , Nagelli Christopher V. , Hewett Timothy E. , Feller Julian A. 
Published: May 2018

Background: Anterior cruciate ligament (ACL) injury has a significant psychological effect, and a negative psychological state is a commonly cited reason for a reduction or cessation of sports participation after ACL reconstruction (ACLR) surgery. Purpose: To identify factors that contribute to an athlete’s psychological readiness to return to sport (RTS) after ACLR. Study Design: Cross-sectional study; Level of evidence, 3. Methods: A cohort of 635 athletes (389 male, 246 female) who underwent ACLR and had been cleared to RTS completed the Anterior Cruciate Ligament–Return to Sport After Injury (ACL-RSI) scale at an average 12 months (range, 11-24 months) after surgery. Demographics (age, sex), sporting outcomes (preinjury frequency), surgical timing (injury to surgery interval), clinical factors (laxity), functional measures (single-limb hop symmetry), and symptoms of pain and function (International Knee Documentation Committee subjective) were also taken, and univariate and multiple regression models were used to determine the association between these and the psychological readiness of the athlete to RTS (ACL-RSI scores). Data for the entire cohort were initially analyzed; then, patients were grouped according to whether they had returned to competitive sport, and the analysis repeated for each group (return/nonreturn). Results: Univariate analysis for the entire group showed that all of the following had a positive effect on psychological readiness: male sex (β = 5.8; 95% CI, 2-10), younger age (β = −0.2; 95% CI, –0.4 to 0.01), a shorter interval between injury and surgery (β = −0.1; 95% CI, −0.1 to −0.02), a higher frequency of preinjury sport participation (β = 5.4; 95% CI, 2-9), greater limb symmetry (β = 0.5; 95% CI, 0.3-0.6), and higher subjective knee scores (β = 1.3; 95% CI, 1.1-1.4). In the multivariate model, subjective knee scores and age significantly accounted for 37% of the variance in psychological readiness ( r2 = 0.37, P < .0001). The only difference between the groups who had and had not returned to sport was that female sex was a significant contributor for the nonreturn group. Conclusion: Self-reported symptoms and function were most associated with psychological readiness to RTS after ACLR surgery. Male patients who participated frequently in sport before ACL injury had higher psychological readiness. Conversely, female patients had a more negative outlook and may therefore benefit more from interventions designed to facilitate a smooth transition back to sport.
Early Prediction of Intensive Care Unit–Acquired Weakness: A Multicenter External Validation Study
Authors: Witteveen Esther , Wieske Luuk , Sommers Juultje , Spijkstra Jan-Jaap , de Waard Monique C. , Endeman Henrik , Rijkenberg Saskia , de Ruijter Wouter , Sleeswijk Mengalvio , Verhamme Camiel , Schultz Marcus J. , van Schaik Ivo N. , Horn Janneke 
Published: May 2018

Objectives: An early diagnosis of intensive care unit–acquired weakness (ICU-AW) is often not possible due to impaired consciousness. To avoid a diagnostic delay, we previously developed a prediction model, based on single-center data from 212 patients (development cohort), to predict ICU-AW at 2 days after ICU admission. The objective of this study was to investigate the external validity of the original prediction model in a new, multicenter cohort and, if necessary, to update the model. Methods: Newly admitted ICU patients who were mechanically ventilated at 48 hours after ICU admission were included. Predictors were prospectively recorded, and the outcome ICU-AW was defined by an average Medical Research Council score <4. In the validation cohort, consisting of 349 patients, we analyzed performance of the original prediction model by assessment of calibration and discrimination. Additionally, we updated the model in this validation cohort. Finally, we evaluated a new prediction model based on all patients of the development and validation cohort. Results: Of 349 analyzed patients in the validation cohort, 190 (54%) developed ICU-AW. Both model calibration and discrimination of the original model were poor in the validation cohort. The area under the receiver operating characteristics curve (AUC-ROC) was 0.60 (95% confidence interval [CI]: 0.54-0.66). Model updating methods improved calibration but not discrimination. The new prediction model, based on all patients of the development and validation cohort (total of 536 patients) had a fair discrimination, AUC-ROC: 0.70 (95% CI: 0.66-0.75). Conclusions: The previously developed prediction model for ICU-AW showed poor performance in a new independent multicenter validation cohort. Model updating methods improved calibration but not discrimination. The newly derived prediction model showed fair discrimination. This indicates that early prediction of ICU-AW is still challenging and needs further attention.
Clinical accuracy of a patient-specific femoral osteotomy guide in minimally-invasive posterior hip arthroplasty
Authors: Schneider Adrian K , Pierrepont Jim W , Hawdon Gabrielle , McMahon Stephen 
Published: May 2018

Introduction: Patient specific guides can be a valuable tool in improving the precision of planned femoral neck osteotomies, especially in minimally invasive hip surgery, where bony landmarks are often inaccessible. The aim of our study was to validate the accuracy of a novel patient specific femoral osteotomy guide for THR through a minimally invasive posterior approach, the direct superior approach (DSA). Methods: As part of our routine preoperative planning 30 patients underwent low dose CT scans of their arthritic hip. 3D printed patient specific femoral neck osteotomy guides were then produced. Intraoperatively, having cleared all soft tissue from the postero-lateral neck of the enlocated hip, the guide was placed and pinned onto the posterolateral femoral neck. The osteotomy was performed using an oscillating saw and the uncemented hip components were implanted as per routine. Postoperatively, the achieved level of the osteotomy at the medial calcar was compared with the planned level of resection using a 3D/2D matching analysis (Mimics X-ray module, Materialise, Belgium). Results: A total of 30 patients undergoing uncemented Trinity acetabular and TriFit TS femoral component arthroplasty (Corin, UK) were included in our analysis. All but one of our analysed osteotomies were found to be within 3 mm from the planned height of osteotomy. In one patient the level of osteotomy deviated 5 mm below the planned level of resection. Conclusion: Preoperative planning and the use of patient specific osteotomy guides provides an accurate method of performing femoral neck osteotomies in minimally invasive hip arthroplasty using the direct superior approach. Level of evidence: IV (Case series)
Outcomes of Vancouver B2 and B3 periprosthetic femoral fractures after total hip arthroplasty in elderly patients
Authors: Moreta Jesús , Uriarte Iker , Ormaza Amaia , Mosquera Javier , Iza Kattalin , Aguirre Urko , Legarreta María José , Martínez-De Los Mozos José Luis 
Published: May 2018

Introduction: The objective was to evaluate clinical and radiological outcomes of Vancouver B2 and B3 periprosthetic femoral fractures in patients older than 65 years treated at our institution from 2000 to 2014. We compared the most common methods of fixation: a modular tapered rectangular titanium stem versus a monoblock tapered stem. Methods: A retrospective review was performed with a minimum follow-up time of 2 years. Patient mobility in the period prior to the fracture and after fracture healing and functional results was assessed according to the Harris Hip Score. Results: A total of 43 Vancouver B2 and B3 periprosthetic fractures fulfilled the inclusion criteria (31 type B2 and 13 type B3). The mean age was 78 years old (66–88 years). The mean follow-up time was 5 years (range 2–12 years). A Wagner stem was used in 19 patients and a modular rectangular stem was implanted in 24 patients. Although fracture union was achieved in 93% of the cases, the mean Harris Hip Score was 73 (34–87) and 41.9% of the patients did not return to their previous ambulatory levels ( p = 0.0049). Dislocation was the most common complication (16.3%). We have found association ( p = 0.07) between subsidence with a mean of 4.14 mm and dislocation. No difference was observed between B2 and B3 fractures or between modular and monoblock stems. Discussion: Although we reported good results of fracture healing, there were functional impairment and a high rate of complications, especially dislocation, in Vancouver B2 and B3 periprosthetic fractures in elderly patients.
Efficacy of Cladribine Tablets in high disease activity subgroups of patients with relapsing multiple sclerosis: A post hoc analysis of the CLARITY study
Authors: Giovannoni Gavin , Soelberg Sorensen Per , Cook Stuart , Rammohan Kottil W , Rieckmann Peter , Comi Giancarlo , Dangond Fernando , Hicking Christine , Vermersch Patrick 
Published: May 2018

Background: In the CLARITY (CLAdRIbine Tablets treating multiple sclerosis orallY) study, Cladribine Tablets significantly improved clinical and magnetic resonance imaging (MRI) outcomes (vs placebo) in patients with relapsing-remitting multiple sclerosis. Objective: Describe two clinically relevant definitions for patients with high disease activity (HDA) at baseline of the CLARITY study (utility verified in patients receiving placebo) and assess the treatment effects of Cladribine Tablets 3.5 mg/kg compared with the overall study population. Methods: Outcomes of patients randomised to Cladribine Tablets 3.5 mg/kg or placebo were analysed for subgroups using HDA definitions based on high relapse activity (HRA; patients with ⩾2 relapses during the year prior to study entry, whether on DMD treatment or not) or HRA plus disease activity on treatment (HRA + DAT; patients with ⩾2 relapses during the year prior to study entry, whether on DMD treatment or not, PLUS patients with ⩾1 relapse during the year prior to study entry while on therapy with other DMDs and ⩾1 T1 Gd+ or ⩾9 T2 lesions). Results: In the overall population, Cladribine Tablets 3.5 mg/kg reduced the risk of 6-month-confirmed Expanded Disability Status Scale (EDSS) worsening by 47% vs placebo. A risk reduction of 82% vs placebo was seen in both the HRA and HRA + DAT subgroups (vs 19% for non-HRA and 18% for non-HRA + DAT), indicating greater responsiveness to Cladribine Tablets 3.5 mg/kg in patients with HDA. There were consistent results for other efficacy endpoints. The safety profile in HDA patients was consistent with the overall CLARITY population. Conclusion: Patients with HDA showed clinical and MRI responses to Cladribine Tablets 3.5 mg/kg that were generally better than, or at least comparable with, the outcomes seen in the overall CLARITY population.
Bursting Fracture of Balloon-Expandable Stent and Pseudoaneurysm Formation in the Left Common Iliac Artery and Endovascular Treatment With Graft Stent
Authors: Kim Min , Lee Dae In , Lee Ju-Hee , Lee Sang Yeub , Bae Jang-Whan , Hwang Kyung-Kuk , Kim Dong-Woon , Cho Myeong-Chan , Kim Sangmin 
Published: May 2018

Purpose: To report successful endovascular treatment of a previously implanted balloon-expandable stent bursting fracture with concomitant large pseudoaneurysm formation in the left common iliac artery (LCIA). Case Report: A 72-year-old man had been previously treated with balloon-expandable stents for severe stenotic lesion in the LCIA and left external iliac artery. Seven years later, the patient complained pain in both lower legs and back. Angiography demonstrated a 3.5-cm-sized pseudoaneurysm in the LCIA with embedded metal fragments around the lesion. An endovascular treatment was selected using a limb extension graft for endovascular aortic aneurysm repair. The device was successfully deployed, and no endoleak was observed. At 1-month follow-up, computed tomography scan confirmed patency of the implanted stent graft devices in the LCIA and the absence of any endoleak. Conclusion: Endovascular approach using a limb extension graft stent for endovascular aortic aneurysm repair can be used for treating stent fracture-related pseudoaneurysm in the common iliac artery.