bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors associated with deaths from suicide in a French nationwide HIV‐infected cohort
Authors: Hentzien M , Cabie A , Pugliese P , Billaud É , Poizot‐Martin I , Duvivier C , Valantin M‐A , Kaladjian A , Dramé M , Bani‐Sadr F ,   The Dat'AIDS Study Group
Published: June 2018

ObjectivesPeople living with HIV (PLHIV) are at a higher risk of dying by suicide than the general population. Epidemiological data regarding determinants of suicide in PLHIV are scarce. The aim of this study was thus to study demographic, socio‐economic, psychiatric history and immunovirological characteristics associated with death from suicide in the French multicenter Dat'AIDS cohort, from January 2000 to July 2013.MethodsThis was a nested case–control study. All deceased PLHIV during the study period who died by suicide and whose medical files could be checked were included as cases. Controls were selected using incidence density sampling. For each case, up to four controls were selected among all actively followed PLHIV at the index date (date of death of cases). Controls were matched for time from HIV diagnosis (5‐year periods) and clinical centre.ResultsSeventy cases and 279 controls were included in the study. By multivariable analysis, the factors significantly associated with death from suicide were: not having children, active or substituted drug consumption, alcohol intake > 20 g/day or history of alcohol abuse, history of depressive disorder and/or of attempted suicide, and psychotropic drug intake. Conversely, age, gender, country of birth, positive HCV serology and HIV‐related factors, such as AIDS status, use of combination antiretroviral therapy (cART), nadir and current CD4 counts and HIV viral load, were not significantly associated with the risk of death from suicide.ConclusionsIn the cART era, HIV‐related factors are not associated with a higher risk of suicide mortality. Suicide prevention measures should target PLHIV with the psychological morbidities observed in our cohort.
Anxiety in the workplace: A comprehensive occupational health evaluation of anxiety disorder in public school teachers
Authors: Jones‐Rincon Amanda , Howard Krista J. 
Published: June 2018

AbstractThe purpose of the study was to systematically assess demographic, occupational, and psychosocial factors associated with Anxiety Disorder in public school teachers. A sample of 3,361 public school teachers was given an online questionnaire, including questions about demographic, occupational, and psychosocial factors. Anxiety Disorder was based on the Patient Health Questionnaire. Univariate analyses and a hierarchical logistic regression were used to determine the key demographic, occupational, and psychosocial factors associated with Anxiety Disorder. Individuals with Anxiety Disorder were significantly more likely to report absenteeism and higher intent to quit (p < .001). The hierarchical logistic regression showed that the factors most associated with the Anxiety Disorder included being Hispanic (p < .01), taught fewer years (p < .05), teaching elementary school (p < .01), higher job involvement (p < .01), higher perceived stress (p < .01), lower physical quality of life (p < .01), major depression (p < .001), and somatization disorder (p < .01). The results from this study identify specific demographic, occupational, and psychosocial factors associated with the presence of anxiety disorder in public school teachers. Future research should examine how implementing changes in the workplace may improve occupational factors such as job control, satisfaction, absenteeism, and intent to quit, which, in turn, may be associated with a reduction in the presence of anxiety disorders.
Digging into the construct of fibrofog: Psychometric properties of the Spanish version of the Multidimensional Inventory of Subjective Cognitive Impairment in patients with fibromyalgia
Authors: Feliu‐Soler Albert , Pérez‐Aranda Adrián , Andrés‐Rodríguez Laura , Butjosa Anna , Díaz Natalia S. , Trujols Joan , Núñez Christian , Stephan‐Otto Christian , Rozadilla‐Sacanell Antoni , Serrano‐Blanco Antoni , Kratz Anna L. , Luciano Juan V. 
Published: June 2018

Perceived dyscognition or fibrofog has been ranked as one major contributor of distress in fibromyalgia (FM). The Multidimensional Inventory of Subjective Cognitive Impairment (MISCI) was devised as a brief and comprehensive self‐report measure of cognitive function in FM. The main objective of the present study was to assess the psychometric properties of the Spanish version of the MISCI. One hundred and twenty patients with FM were included, and dimensionality, reliability, and validity of the MISCI were evaluated. Data from brain imaging (N = 61) were also used in validity analyses. Known‐groups validity was evaluated by including a subset of 45 patients without FM in partial/total remission from depression. Sensitivity to change was assessed after a mindfulness‐based intervention. Spanish version of the MISCI exhibited a one‐factor structure, excellent internal consistency, and good convergent validity with symptomatology and gray matter volumes in anterior and middle cingulate cortices. Significant improvements in MISCI scores after a mindfulness‐based intervention were reported. An additive effect of FM and depression regarding MISCI scores was also observed. Self‐reported depression, anxiety, and problems in balance predicted the 38% of the MISCI variance. The Spanish version of the MISCI is a valuable instrument to include in FM research and clinical practice.
Trees as habitat islands: Temporal variation in alpha and beta diversity in epiphytic laurel forest bryophyte communities
Authors: Patiño Jairo , Gómez‐Rodríguez Carola , Pupo‐Correia Aida , Sequeira Miguel , Vanderpoorten Alain 
Published: June 2018

AbstractAimTrees represent striking examples of habitat islands, with various degrees of spatial isolation and evolving properties during their life cycle. Here, we investigate whether changes in habitat conditions, dispersal limitations or competition cause variation in patterns of epiphytic species richness and turnover.LocationMadeira island.TaxonBryophytes.MethodsUsing linear mixed effect models, we test whether species richness exhibits a monotonic or hump‐shaped relationship with time. Two groups of host‐tree species, late‐ and early‐successional, were considered. We further identify the mechanisms explaining the observed variation in species composition by dividing beta diversity into its nestedness (βsne) and turnover (βsim) components and correlating them with tree age and geographical distance among trees.ResultsThe best‐fit models all included tree age (T), but its quadratic term (T2) and tree height (H, here a surrogate of area) were not systematically included. βsim, but not βsne, correlated with host‐tree age, and both βsim and βsne correlated with geographical distance.Main conclusionsTree age was consistently included in all of the best‐fit models, reflecting the progressive increase in epiphyte bryophyte species richness through time. The limited contribution of T2 and H to the best models suggests that competition for space is not a key factor on mature trees. The correlation of βsim, but not βsne, with host‐tree age, and of βsim and βsne with distance among trees, suggests that variation in species composition is caused by (1) temporal community shifts due to allogenic drivers and (2) dispersal limitations, which are reflected by the higher similarity of the epiphyte communities on clustered trees rather than by an increasing probability of colonization with tree age. Since actual ancient laurel forests may no longer exist in Madeira, the conservation of clusters of late‐successional trees, enhancing connectivity at small spatial scales, is of utmost importance for the conservation and recovery of the unique laurel forest epiphytic flora.
HORIZONTAL MISMATCH BETWEEN EMPLOYMENT AND FIELD OF EDUCATION: EVIDENCE FROM A SYSTEMATIC LITERATURE REVIEW
Authors: Somers Melline A. , Cabus Sofie J. , Groot Wim , van den Brink Henriëtte Maassen 
Published: June 2018

AbstractThis paper provides a systematic review of the growing literature on the poor match between employees’ field degree and the job requirements, also referred to as horizontal mismatch. We identify the different definitions used in the literature and find that each measure of horizontal mismatch yields substantially different incidence rates. We discuss the validity of the different measures and conclude that a more uniform definition of horizontal mismatch is needed. The likelihood of horizontal mismatch is among other things determined by the extent to which employees possess general skills as opposed to occupation‐specific skills, and, it appears to be more frequently present among older workers. Compared to well‐matched employees, horizontally mismatched workers generally incur a wage penalty, are less satisfied with their jobs, and are more likely to regret their study programme. The ensuing findings offer guidance to prevent horizontal mismatch as well as a roadmap for future research.
It is both possible and safe to perform coronary angiography through the same radial artery, after retrograde recanalization of radial artery occlusion, following a previous coronary angiography
Authors: Balaban Yakup , Elevli Murat G. 
Published: June 2018

IntroductionRadial artery occlusions (RAOs) impose an important problem that limit transradial interventions. In this study, we represent that it is possible to perform interventions through occluded radial arteries.MethodTwenty‐five patients with RAO who had retrograde flow shown by doppler ultrasonography were enrolled into our study. After preparing the radial region, the radial artery was accessed with a puncture needle. A 0.014″ guidewire was introduced into the brachial artery via the radial artery with the aid of balloon back up. Lesion was predilated with a drug coated peripheral balloon, and a sheath was placed at the end.ResultsRadial artery recanalization could be established in 22 of 25 cases and coronary angiography could be performed from those occluded radial arteries. Neither the occlusion duration nor the caliber of the radial artery had any effect on the success rate of recanalization attempts. Two patients had a hematoma because of the intervention and there were no other complications.The patency rates at 1 month follow up have been only 33.4%, too much lower than we expected.Discussion and ConclusionIn patients with RAO because of a previous angiographic intervention via their radial arteries may be reintervened from their occluded radial artery safely and effectively. So, our procedure is not intended for neither the recanalization nor keeping the patency of the radial artery, but suitable for those patients in whom other routes of intervention are not wanted.
Comparison of device‐supported sensorimotor training and splint intervention for myofascial temporomandibular disorder pain patients
Authors: Giannakopoulos N. N. , Rauer A.‐K. , Hellmann D. , Hugger S. , Schmitter M. , Hugger A. 
Published: June 2018

SummaryThis study was to compare the short‐term therapeutic efficacy of device‐supported sensorimotor training with that of standard splint therapy for patients with myofascial temporomandibular disorder (TMD) pain over a treatment period of 3 months. We tested the hypothesis that both types of intervention are equally effective for pain reduction. In addition, the electromyographic (EMG) activity of the temporal and masseter muscles was recorded under conditions of force‐controlled submaximum and maximum biting in intercuspation. Of consecutive patients seeking treatment for non‐odontogenic oro‐facial pain, 45 patients with myofascial TMD pain (graded chronic pain status, GCPS, I and II) were randomly assigned to 2 treatment groups (sensorimotor training and conventional splint treatment). Patients were evaluated 4 times (initial examination, 2, 6 and 12 weeks later) by use of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Electromyographic activity was recorded at the initial session and after 3 months. Ease‐of‐use of the treatment options was also evaluated. Significant (P < .0001) pain reduction (sensorimotor training 53%, splint therapy 40%) was achieved for both groups, with no significant differences (P > .05) between the groups. Force‐controlled sub‐maximum normalized electromyographic activity was significantly different between T0 and T3 for group A (sensorimotor training, P < .05) but was not significantly different for group B (splint, P > .05). For normalized maximum‐biting EMG activity in intercuspation, however, a significant increase in EMG activity was observed for group A for the masseter and temporal muscles (P < .001) and for group B for the masseter muscle only (P < .001). Moreover, sensorimotor training was significantly (P < .05) less easy to use than the splint. The results of this study confirm the pain‐reducing effect of sensorimotor training for patients with myofascial TMD pain (GCPS I and II). This innovative active treatment might be a promising option for TMD pain patients.
Gas6 protein induces invasion and reduces inflammatory cytokines in oral squamous cell carcinoma
Authors: Hirschi Kelsey M. , Chapman Steven , Hall Parker , Ostergar Adam , Winden Duane R. , Reynolds Paul R. , Arroyo Juan A. 
Published: June 2018

BackgroundGas6 protein is involved in the progression of cancers and has been demonstrated to have a role in inflammation. Oral squamous cell carcinoma is a common form of oral cancer, and it commonly expresses Gas6. Our objective was to determine the effects of Gas6 on oral squamous cell carcinoma invasion and identify signaling molecules and cytokines associated with Gas6‐mediated invasion.MethodsCa9‐22 cells were cultured in the presence or absence of Gas6. Real‐time cell invasion was evaluated, and cultured cells were lysed for Western blot analysis. Cell medium was collected and assayed for cytokine elaboration.ResultsTreatment of cells with Gas6 resulted in: (i) increased invasion, (ii) increased expression of Gas6 and AXL receptor, (iii) reduced invasion when AXL was inhibited, (iv) decreased ERK activation, (v) increased AKT activation, and (vi) decreased secretion of G‐CSF, IL‐2, IL‐6, and IL‐8.ConclusionsGas6 increases invasion of oral squamous cell carcinoma, and the invasion correlates with the increased AKT and the downregulation of pro‐inflammatory cytokines. These results may prove useful in providing avenues that explain the role of Gas6 in the development and progression of oral squamous cell carcinoma.
Impact of systemic sclerosis oral manifestations on patients’ health‐related quality of life: A systematic review
Authors: Smirani Rawen , Truchetet Marie‐Elise , Poursac Nicolas , Naveau Adrien , Schaeverbeke Thierry , Devillard Raphaël 
Published: June 2018

BackgroundOropharyngeal features are frequent and often understated in the treatment clinical guidelines of systemic sclerosis in spite of important consequences on comfort, aesthetics, nutrition and daily life. The aim of this systematic review was to assess a correlation between the oropharyngeal manifestations of systemic sclerosis and patients’ health‐related quality of life.MethodsA systematic search was conducted using four databases [PubMed®, Cochrane Database®, Dentistry & Oral Sciences Source® and SCOPUS®] up to January 2018, according to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses. Grey literature and hand search were also included. Study selection, risk bias assessment (Newcastle‐Ottawa scale) and data extraction were performed by two independent reviewers. The review protocol was registered on PROSPERO database with the code CRD42018085994.ResultsFrom 375 screened studies, 6 cross‐sectional studies were included in the systematic review. The total number of patients included per study ranged from 84 to 178. These studies reported a statistically significant association between oropharyngeal manifestations of systemic sclerosis (mainly assessed by maximal mouth opening and the Mouth Handicap in Systemic Sclerosis Scale) and an impaired quality of life (measured by different scales). Studies were unequal concerning risk of bias mostly because of low level of evidence, different recruiting sources of samples and different scales to assess the quality of life.ConclusionThis systematic review demonstrates a correlation between oropharyngeal manifestations of systemic sclerosis and impaired quality of life, despite the low level of evidence of included studies. Large‐scaled studies are needed to provide stronger evidence of this association.
Characterization of matrix material in Northwest Africa 5343: Weathering and thermal metamorphism of the least equilibrated CK chondrite
Authors: Dunn Tasha L. , Battifarano Oriana K. , Gross Juliane , O'Hara Emma J. 
Published: June 2018

AbstractBased on the chemical heterogeneity of chondrule and matrix olivine, Northwest Africa (NWA) 5343 is the least metamorphosed CK chondrite reported so far. To better constrain the lower limit of metamorphism in the CK chondrites, we performed a detailed analysis of matrix material in NWA 5343, including characterization of the texture and bulk composition and analyses of individual silicate minerals. Results suggest that NWA 5343 is petrologic type 3.6 or 3.7. Although silicate minerals in the matrix seem to be equilibrated to roughly the same extent throughout the sample, there are recognizable differences in grain size and shape. These textural differences may be the result of transient heating events during impacts, which would be likely on the CK chondrite parent body. The difference between the extent of chemical equilibration and texture may also suggest that grain size and shape are still sensitive to metamorphism at petrologic subtypes where silicate mineral equilibration is nearly complete (e.g., >3.7). Carbonate material present in NWA 5343 is a product of terrestrial weathering; however, infiltration of a Ca‐bearing fluid did not influence the composition of silicate minerals in the matrix. To evaluate the possibility of a continuous metamorphic sequence between the CV and CK chondrites, the bulk matrix composition of NWA 5343 is compared to the CVred chondrite, Vigarano. Although the matrix composition of NWA 5343 could be derived by secondary processing of a Vigarano‐like precursor, porosity and texture of matrix olivine in NWA 5343 are hard to reconcile with a continuous metamorphic sequence.
Electroacupuncture via chronically implanted electrodes improves gastric dysmotility mediated by autonomic‐cholinergic mechanisms in a rodent model of functional dyspepsia
Authors: Zhang S. , Li S. , Liu Y. , Ye F. , Yin J. , Foreman R. D. , Wang D. , Chen J. D. Z. 
Published: June 2018

AbstractBackgroundElectroacupuncture (EA) has been shown to be effective in reducing symptoms in patients with functional dyspepsia (FD). However, its mechanisms remain largely unknown. The aim of this study was to investigate mechanisms of the prokinetic effects of EA in a rodent model of FD.MethodsA FD model was established by neonatal treatment of iodoacetamide (IA). Eight weeks later, the rats were implanted with electrodes in the stomach for the measurement of gastric slow waves (GSW) and electrodes into acupoints ST36 for EA. Autonomic functions were assessed by the spectral analysis of heart rate variability.Key Results(i) The IA‐treated rats (“FD” rats) showed increased dysrhythmia in both fasting and fed states (P < .01) as well as during rectal distention (P < .02). EA reduced the percentage of dysrhythmia (P < .05 for both fasting and fed) and normalized RD‐induced impairment in GSW in “FD” rats. Atropine blocked the effect of EA on GSW. (ii) “FD” rats showed delayed gastric emptying (P = .001 vs control) that was accelerated with EA (P = .01, vs sham‐EA). (iii) “FD” rats showed increased plasma norepinephrine (P = .006, vs control) that was suppressed with EA (P = .003) and reduced vagal activity that was improved with EA.Conclusions and InferencesGastric motility (GSW and GE) is impaired in rats treated with IA, possibly attributed to impaired autonomic functions. EA improves GSW and accelerates GE mediated via the autonomic and cholinergic mechanisms.
Ultrastructure and optics of the prism‐like petal epidermal cells of Eschscholzia californica (California poppy)
Authors: Wilts Bodo D. , Rudall Paula J. , Moyroud Edwige , Gregory Tom , Ogawa Yu , Vignolini Silvia , Steiner Ullrich , Glover Beverley J. 
Published: June 2018

Summary

The petals of Eschscholzia californica (California poppy) are robust, pliable and typically coloured intensely orange or yellow owing to the presence of carotenoid pigments; they are also highly reflective at certain angles, producing a silky effect.

To understand the mechanisms behind colour enhancement and reflectivity in California poppy, which represents a model species among early‐divergent eudicots, we explored the development, ultrastructure, pigment composition and optical properties of the petals using light microscopy and electron microscopy combined with both spectrophotometry and goniometry.

The elongated petal epidermal cells each possess a densely thickened prism‐like ridge that is composed primarily of cell wall. The surface ridges strongly focus incident light onto the pigments, which are located in plastids at the cell base.

Our results indicate that this highly unusual, deeply ridged surface structure not only enhances the deep colour response in this desert species, but also results in strongly angle‐dependent ‘silky’ reflectivity that is anisotropic and mostly directional.