bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of fluoroethyl tyrosine positron emission tomography-computed tomography scan in differentiating ewing's sarcoma from osteomyelitis
Authors: Aggarwal Hitesh , D'souza Maria , Panwar Puja , Jyotsna Neeru , Alvi Tauheed , Solanki Yachna , Kumar Tarakant , Sharma Rajnish 
Published: January 2019

AbstractEwing's sarcoma is a kind of undifferentiated reticulocytic sarcoma, which was first reported in 1921 by James Ewing. It is difficult to differentiate Ewing's sarcoma from osteomyelitis on computed tomography (CT) and X-ray and hence cytological confirmation is needed. Fluorodeoxy glucose being a nonspecific tracer cannot differentiate between malignant and inflammatory lesions. However, it is found that Ewing's sarcoma has increased LAT1 transporter expression at the cell surface. This property has been utilized to specifically target the tumor cells and differentiate them from inflammatory lesions. 18F-fluoroethyl tyrosine (FET) is a radiotracer which shows increased uptake in tumors having LAT1 expression and no uptake in inflammatory lesions. Thus, FET positron emission tomography-computed tomography can serve as a useful tool in diagnosing recurrence or residual Ewing's sarcoma from infective pathology. Besides, it is also helpful in monitoring response to therapy.
Low-radiation of technetium-99m-sestamibi and single-photon emission computed tomography/computed tomography to diagnose parathyroid lesions
Authors: Vaiman Michael , Cohenpur Mehrzad , Halevy Ariel , Volkov Olga , Gold Ruth , Peer Michael , Golan Haim , Gavriel Haim 
Published: January 2019

AbstractWe compared preoperative regular activity and low-activity radiology-based predictions with real surgical and pathological findings for parathyroidectomy surgery. The study retrospectively analyzed 54 consecutive cases (2009–2016) for benign tumor removal. Technetium-99m (Tc-99m)-sestamibi was used as a diagnostic radiopharmaceutical for diagnostic dual-phase parathyroid scintigraphy and single-photon emission computed tomography/computed tomography. We assessed images obtained with the radiation activity of 925 megabecquerel (MBq) and images obtained with the activity of 185 MBq. The study compared preoperative evaluation of tumor presence, multiplicity, location, and the type of pathology with actual data that were revealed during the operation and pathological investigation. The agreement between preoperative radiological prediction and actual location, number, and type of the parathyroid lesions was achieved in 98.4% (n = 61/62 lesions). The agreement between 925 MBq-based and 185-MBq based investigations was 100%. The agreement between radiological and pathological findings was 100% for both investigations. Our data suggest that the radioactivity of 185 MBq applied in the evaluation of the parathyroid glands provides results similar to the currently used 925–1110 MBq if used for diagnostic dual-phase parathyroid scintigraphy with Tc-99m-sestamibi. Such radioactivity may reduce the exposure to radiation of the patients and the staff without compromising results of the investigation.
Synchronous bilateral renal cell carcinomas in “Asynchrony of metabolism”
Authors: Aurangabadkar Hrushikesh Upendra , Palle Lalitha , Ali Zakir 
Published: January 2019

AbstractHere, we present a case of bilateral synchronous renal cell carcinoma in a 52-year-old male patient, who underwent fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) scan followed by surgical removal of both tumors. On PET scan, left renal mass showed intense FDG uptake while uptake in the right renal mass was minimal. Histopathologically, both tumors were conventional clear cell carcinoma (Fuhrman Grade III). Only the FDG-avid tumor in the left kidney had lymphovascular invasion and necrosis, which are markers of aggressive form of any tumor. FDG PET-CT can act as strong and noninvasive prognostic parameter that could help to identify patients with aggressive disease before treatment.
Ensuring effective and sustainable radionuclide delivery and its impact on the development of nuclear medicine in the developing world with special reference to Nigeria
Authors: Orunmuyi T. Akintunde , Sathekge M. Mike , Buscombe R. John 
Published: January 2019

AbstractRecent activities of Boko Haram, a local extremist group in Nigeria, raise concerns about a nuclear terrorist attack. Whereas nuclear medicine (NM) relies on the timely delivery of radioactive sources, a robust security structure that assures public safety is the backbone for its beneficial use. NM radionuclides have short half-lives and carry an insignificant risk for acts of terrorism. Yet, their importation and delivery in Nigeria receive undue scrutiny in a bid to implement a strict nuclear security regime. These actions prevent timely delivery of radionuclides with direct consequences on quality and economic viability of nuclear medicine. There have been no accounts of terrorist acts accomplished with NM radionuclides. Thus, it is important the NM community question the current approach that has contributed to the loss of NM services in Nigeria and proposes a more logical strategy for securing their supply. We also highlight the need for developing local pragmatic solutions when implementing global recommendations in developing countries.
O campo do patrimônio cultural, redes e intersecções
Authors: Souza Giane Maria 
Published: January 2019

Este artigo possui o escopo de debater patrimônio cultural como campo antropológico e historicamente articulado ao atentar para apropriações do patrimônio cultural a partir de variações conceituais e interesses sociais múltiplos. Como construção histórica o patrimônio é marcado por negociações e disputas para o seu reconhecimento social, contudo, iniciativas populares dessacralizam os sentidos da patrimonialização e geram práticas sociais que incidem novos olhares sobre o cotidiano ordinário. Desta forma, experiências da cultura popular são analisadas na perspectiva do videoclipe de Néstor Canclini, imagens e narrativas são relacionadas e refletem os usos do patrimônio por meio da ocupação religiosa de uma praça, da relação de pertencimento de um bairro com o teatro, de uma obra do artista Tunga a um museu do lixo criado com curadoria dos trabalhadores. Estas experiências subvertem a ótica do patrimônio como fetiche mercadológico para práticas sociais ordinárias e transformadoras de redes e intersecções.
The European Climate Research Alliance (ECRA): Collaboration from bottom-up
Authors: Hoke Winfried , Swierczynski Tina , Braesicke Peter , Lochte Karin , Shaffrey Len , Drews Martin , Gregow Hilppa , Ludwig Ralf , Nilsen Jan Even Øie , Palazzi Elisa , Sannino Gianmaria , Smedsrud Lars Henrik ,   ECRA network
Published: January 2019

Abstract. The European Climate Research Alliance (ECRA) is an association
of leading European research institutions in the field of climate research
(http://www.ecra-climate.eu/, last access: 6 December 2018). ECRA is a bottom-up initiative and helps to facilitate
the development of climate change research, combining the capacities of
national research institutions, and inducing closer ties between existing
national research initiatives, projects and infrastructures. ECRA works as an
open platform to bring together climate researchers, providing excellent
scientific expertise for policy makers and of societal relevance. The ECRA
Board consists of representatives of ECRA partners and decides on governance,
scientific priorities, and organisational matters. Currently organized into four Collaborative Programmes, climate scientists
share their knowledge, experience and expertise to identify the most
important research requirements for the future, thus developing a foresight
approach. The CPs cover the topics: (1) Arctic variability and change,
(2) Sea level changes and coastal impacts, (3) Changes in the hydrological cycle
and (4) High impact events. The CP activities are planned in workshops and
participation is open to all interested scientists from the relevant
research fields. In particular, young researchers are actively encouraged to
join the network. Each CP develops its joint research priorities for shaping
European research into the future. Because scientific themes are
interconnected, the four Collaborative Programmes interact with each other,
e.g. through the organization of common workshops or joint applications. In
addition, the Collaborative Programme leads attend the Board meetings. The different formats of ECRA meetings range from scientific workshops to
briefing events and side events at conferences to involve different groups
of interests. This facilitates the interaction of scientists, various
stakeholder groups and politicians. A biennial open ECRA General Assembly
that is organised in Brussels represents an umbrella event and acts as a
platform for discussion and contact with stakeholders. This event is an
excellent opportunity to jointly discuss research priorities of high
societal relevance.
Assessing the effect of flood restoration on surface–subsurface interactions in Rohrschollen Island (Upper Rhine river – France) using integrated hydrological modeling and thermal infrared imaging
Authors: Jeannot Benjamin , Weill Sylvain , Eschbach David , Schmitt Laurent , Delay Frederick 
Published: January 2019

Abstract. Rohrschollen Island is an artificial island of the large Upper Rhine river
whose geometry and hydrological dynamics are the result of engineering works
during the 19th and 20th centuries. Before its channelization, the Rhine
river was characterized by an intense hydromorphological activity which
maintained a high level of biodiversity along the fluvial corridor. This
functionality considerably decreased during the two last centuries.
In 2012, a restoration project was launched to reactivate typical alluvial
processes, including bedload transport, lateral channel dynamics, and
surface–subsurface water exchanges. An integrated hydrological model has been
applied to the area of Rohrschollen Island to assess the efficiency of the
restoration regarding surface and subsurface flows. This model is calibrated
using measured piezometric heads. Simulated patterns of water exchanges
between the surface and subsurface compartments of the island are checked
against the information derived from thermal infrared (TIR) imaging. The simulated
results are then used to better understand the evolutions of the
infiltration–exfiltration zones over time and space and to determine the
physical controls of surface–subsurface interactions on the hydrographic
network of Rohrschollen Island. The use of integrated hydrological modeling
has proven to be an efficient approach to assess the efficiency of
restoration actions regarding surface and subsurface flows.
Effects of Intramuscular Alfaxalone/Acepromazine on Echocardiographic, Biochemical, and Blood Gas Measurements in Healthy Cats
Authors: Kim Boeun , Jang Min , Sohn Jungmin , Oh Hyunjung , Jo Sangmin , Choi Mincheol , Lee Inhyung , Yoon Junghee 
Published: January 2019

ABSTRACTThe effects of intramuscular injection of alfaxalone ([ALF] 5 mg/kg), acepromazine ([ACE] 0.05 mg/kg), and an ALF-ACE combination ([AA] 0.025 mg/kg ACE followed by 2.5 mg/kg ALF) on the sedation, echocardiographic, biochemical, and blood gas indexes and recovery were evaluated in seven cats. No sedation was obtained with ACE, and sedation scores were higher with ALF than with AA treatment. Compared with baseline, an increase in heart rate occurred after ACE, and all treatments caused a decrease in systemic arterial pressure. Decreased left ventricular internal dimension in diastole, end-diastolic volume of the left ventricle, stroke volume, and left atrial dimension were identified after AA. There were minimal changes in echocardiographic variables after ALF. Biochemical and blood gas analysis showed no significant changes after all treatments. Although the difference in quality of recovery between the AA and ALF treatment groups was insignificant, all cats treated with AA or ALF showed ataxia. The AA combination did not change the recovery score, and tremor and twitching were identified more frequently with AA than ALF. ALF had no significant effects on echocardiographic, biochemical, or blood gas variables. ALF could be considered a useful sedative option for diagnostic procedures and echocardiography in cats.
Suspected Compartment Syndrome, Consumptive Thrombocytopenia, and Anemia Secondary to a Ruptured Arterial Aneurysm or Pseudoaneurysm Following Multiple Stifle Surgeries
Authors: Levenson Michael , Calabro Janine M. , Crawford Jason R. , Hart Samantha K. 
Published: January 2019

ABSTRACT
A 12 yr old male neutered beagle was presented on transfer to the intensive care unit with severe anemia, thrombocytopenia, and bruising detected 1 day after undergoing tibial plateau leveling osteotomy surgery. The patient had undergone extra-capsular stifle stabilization surgery 14 wk prior to treat ligament disease in the same knee. Laboratory testing and treatment for anemia, presumptive immune-mediated thrombocytopenia, and possible hemostatic disorder was initiated. A persistent anemia, progressive thrombocytopenia, and the development of a firm swelling and neurologic impairment in the limb raised concerns for compartment syndrome (CS). A musculoskeletal ultrasound revealed a large aneurysm in the caudal thigh surrounded by abnormal muscle tissue. The patient underwent amputation of the limb and recovered without further complication. Pathology findings were consistent with the development of femoral CS secondary to a ruptured peripheral arterial aneurysm or a pseudoaneurysm. A consumptive thrombocytopenia and regenerative anemia were attributed to periodic or progressive thrombosis of the vessel and regional hemorrhage. Postoperative CS can develop in combination with peripheral arterial aneurysm or pseudoaneurysm, and screening for vascular abnormalities as well as CS should be considered in complicated recovery from orthopedic surgery with compatible clinical signs including progressive soft tissue swelling, persistent anemia, and thrombocytopenia.
Effect of Targeted Pulsed Electromagnetic Field Therapy on Canine Postoperative Hemilaminectomy: A Double-Blind, Randomized, Placebo-Controlled Clinical Trial
Authors: Alvarez Leilani X. , McCue John , Lam Nathaniel K. , Askin Gulce , Fox Philip R. 
Published: January 2019

ABSTRACTIntervertebral disc disease is one of the leading causes of paralysis in dogs. Pulsed electromagnetic field (PEMF) therapy has been advocated for improving wound healing and pain reduction; however, robust clinical trials are lacking. The present prospective, double-blind, placebo-controlled trial evaluated targeted PEMF therapy administered to 53 client-owned dogs who underwent hemilaminectomy for naturally occurring disk extrusion intervertebral disc disease. The dogs were randomized to receive either targeted PEMF (n = 27) or placebo treatment (n = 28). Wound healing, evaluated by visual analog score and wound evaluation scale, was significantly improved at 6 wk postoperatively in the treatment compared with the control group (P = .010 and .023, respectively). Pain medications were administered less frequently in dogs receiving PEMF treatment during the 7 day postoperative period compared with the control treatment group (P = .010) with codeine administered 1.8 times more frequently in the control group. No untoward effects were recorded in either treatment group. More frequent evaluation of outcome measures with larger patient numbers, as well as histologic samples, may be useful in future studies. Dogs receiving PEMF therapy following postoperative hemilaminectomy demonstrated improved wound scores at 6 wk and reduced mean number of owner-administered pain medications compared with the control group therapy.
Constrictive Bronchiolitis Obliterans in a Dog
Authors: Wylie Stacey Lynn , Langlois Daniel , Carey Stephan , Nelson Nathan C. , Williams Kurt J. 
Published: January 2019

ABSTRACTA 2 yr old, neutered male rottweiler was evaluated for a chronic cough that had acutely worsened. Computed tomographic examination revealed a diffuse alveolar pattern in the right, middle, and left cranial lung lobes. Aerated parenchymal tissue was not observed in the left cranial lung lobe, and both lobes were markedly decreased in volume. Lobectomy of the right middle and left cranial lung lobes was performed. Histopathologic examination of both lungs identified alveolar collapse associated with marked chronic bronchial and bronchiolar luminal concentric fibrosis leading to reduced airway lumen diameter and bronchiolar destruction. The clinical signs and airway pathology were consistent with constrictive bronchiolitis obliterans. The dog remained stable for over 2 yr with glucocorticoid therapy and intermittent antimicrobics. Although the polypoid form of bronchiolitis obliterans has been described in cattle and occasionally in dogs, constrictive bronchiolitis obliterans has not been reported previously in veterinary species.
Sequential Treatment of a Large Pituitary Corticotroph Neoplasm and Associated Neurological Signs in a Dog
Authors: Del Magno Sara , Fracassi Federico , Grinwis Guy C.M. , Mandrioli Luciana , Gandini Gualtiero , Rossi Federica , Sirri Rubina , Pisoni Luciano , Tryfonidou Marianna A. , Meij Björn P. 
Published: January 2019

ABSTRACT
No standardized treatment guidelines are reported in veterinary medicine for dogs with large pituitary corticotroph neoplasms causing neurological signs, and such dogs usually have a short overall survival. When these dogs undergo pituitary surgery and the tumor regrows there are few reports of subsequent treatments.
A 7 yr old male Maltese diagnosed with pituitary-dependent hypercortisolism developed seizures in conjunction with a large pituitary corticotroph adenoma and underwent transsphenoidal hypophysectomy. After 3 yr of clinical remission, hypercortisolism recurred, and trilostane therapy was initiated. One year later, the dog developed new neurological signs and computed tomography revealed regrowth of a large pituitary mass that was then treated with radiation therapy. The dog lived disease-free for 3 more yr. At postmortem examination, a more aggressive pituitary neoplasm than the one examined at the time of surgery was found, which is suggestive of malignant transformation into a carcinoma despite the absence of convincing metastasis.
Nadeelcompensatie onder de Omgevingswet: hoe een stelselherziening in het omgevingsrecht leidt tot een systeemwijziging van het nadeelcompensatierecht
Authors: van den Broek G.M. (Berthy) 
Published: January 2019

Nadeelcompensatie onder de Omgevingswet: hoe een stelselherziening in het omgevingsrecht leidt tot een systeemwijziging van het nadeelcompensatierecht
De stelselherziening in het omgevingsrecht heeft consequenties voor de vormgeving van de nadeelcompensatieregeling in de Omgevingswet (Ow). Bij het opstellen van de nadeelcompensatieregeling in de Ow zijn door de minister drie fundamentele keuzes gemaakt, die afwijken van de keuzes die de Awb-wetgever in 2013 heeft gemaakt. De eerste keuze is dat art. 15.1 Ow een wettelijke, limitatieve lijst van schadeoorzaken bevat, waarop uitsluitend besluiten zijn vermeld die rechtstreeks bindend zijn voor burgers. Een tweede keuze is dat bij ‘indirecte schade’ de peildatum voor de schadevergoeding wordt verschoven van het omgevingsplan naar de verlening van de omgevingsvergunning of de start van de vergunningsvrije activiteit. Een derde keuze is dat in art. 15.5 t/m 15.7 Ow materiële bepalingen zijn opgenomen die afwijken van de in de jurisprudentie ontwikkelde criteria. Naar aanleiding van de consultatiereactie en het advies van de Raad van State worden deze keuzes in dit artikel nader besproken.
Agradecimento aos Revisores da Revista Brasileira de Medicina de Família e Comunidade (RBMFC) que avaliaram manuscritos em 2018
Authors: Sarti Thiago Dias , Fontenelle Leonardo Ferreira 
Published: January 2019

A Revista Brasileira de Medicina de Família e Comunidade (RBMFC) agradece aos Avaliadores listados abaixo que atuaram como revisores ad hoc durante o ano de 2018, dedicando horas voluntariamente para a emissão de pareceres técnicos sobre manuscritos submetidos a esta revista.
Health Benefits of Culinary Herbs and Spices
Authors: Jiang T Alan 
Published: January 2019

Abstract
Spices and herbs have been in use for centuries both for culinary and medicinal purposes. Spices not only enhance the flavor, aroma, and color of foodand beverages, but they can also protect from acuteand chronic diseases. More Americans are considering the use of spices and herbs for medicinal and therapeutic/remedy use, especially for various chronicconditions. There is now ample evidence that spicesand herbs possess antioxidant, anti-inflammatory, antitumorigenic, anticarcinogenic, and glucose- and cholesterol-lowering activities as well as properties that affect cognition and mood. Research over the past decade has reported on the diverse range of health properties that they possess via their bioactive constituents, including sulfur-containing compounds, tannins, alkaloids, phenolic diterpenes, andvitamins, especially flavonoids and polyphenols. Spices and herbs such as clove, rosemary, sage, oregano, and cinnamon are excellent sources of antioxidants with their high content of phenolic compounds. It is evident that frequent consumption of spicy foods was also linked to a lower risk of death from cancer and ischemic heart and respiratory system diseases. However, the actual role of spicesand herbs in the maintenance of health, specifically with regards to protecting against the development of chronic, noncommunicable diseases, is currently unclear.This review highlights potential health benefits ofcommonly used spices and herbs such as chili pepper, cinnamon, ginger, blackpepper, turmeric, fenugreek, rosemary, and garlic.
Analysis of water quality in the watershed Brazilian semiarid
Authors: Silva Viviane Farias , Pessoa Dihego Souza , Lima Thalis Leandro Bezerra , Cosme Ana Maria Ferreira , Lima Vera Lucia Antunes 
Published: January 2019

Water is a renewable natural resource, important for maintenance of life on the entire planet. Even with this significance is a feature that has been degraded and reduced the quality to use. In the Brazilian semi-arid region water scarcity by influencing the quality of life of the population, directly affecting the socio-economic and development means. In this context, the present research was conducted aiming to evaluate the water quality in the watershed Brazilian semiarid. The survey was conducted in three watersheds (Capibaribe river, Ipojuca river and Igarassu river) in the State of Pernambuco, Brazil. Water Quality Index (WQI) and Biochemical Oxygen Demand (BOD) annual averages of the year 2006 to 2015. In Capibaribe river watershed the largest concentrations of BOD occurred in 213, 2014 and 2015, with average was 4.95 mg/L. By increasing the BOD value there is a reduction of WQI. The Igarassu river, it was verified that from 2006 to 2014 the hydrographic basin has water quality classified as good. The BOD in the waters of the Ipojuca river has little influence on the water quality index.There is a degradation on the quality of water of basins due mainly to anthropic pollution.