bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid Screening and Quantification of Multi-Class Multi-Residue Veterinary Drugs in Pork by a Modified Quechers Protocol Coupled to UPLC-QOrbitrap HRMS
Authors: Wang Liya , Qi Chunyan , Wang Lidan , Wang Tingcai , Lei Yi , Zeng Xuefang , Liu Jiafei , Liang Xuxia , Huang Lixin , Wu Yongning 
Published: September 2019

Background:A rapid and simple analytical method for the screening and quantification of multi-residues was established by a quick, easy, cheap, effective, rugged and safe (QuEChERS) approach coupled to ultra-performance liquid chromatography and electrospray ionization quadrupole orbitrap high-resolution mass spectrometry (UPLC-Q-Orbitrap HRMS). A total number of 59 veterinary drugs were investigated, which belonged to 12 classes, such as β-agonist, quinolones, sulfonamides, tetracyclines, lincomycin series, triphenylmethane, nitroimidazoles, macrolides, amide alcohols, quinoxalines, steroid hormone and sedatives.Methods:The factors which influence the determination of veterinary drugs residues, such as mobile phase, extract solvent, clean up sorbent, and re-dissolved solvent, were optimized by the single factor experiment. The method was sufficiently validated by using the parameters of linearity, sensitivity, accuracy, and repeatability.Results:The response of the detector was linear for 59 veterinary drug residues in extensive range (two to three orders of magnitude) with a high coefficient of determination (R2) (0.9995-0.9998). The limit of quantification (LOQ) ranged from 0.1μg/kg to 2.0μg/kg for 59 veterinary drug residues in pork samples. The repeatability was in the range of 1.0%-9.5%. Average recoveries of 59 veterinary drugs at three spiked levels ranged from 53.7%-117.8% with relative standard deviation (RSD) of 1.9%-13.9%. The full MS scan coupled with data-dependent MS/MS mode was applied for screening the target compounds to simultaneously obtain the accurate mass of parent ion and the mass spectrum of fragments. Elemental composition, accurate mass, and retention time and characteristic fragment ions were used to establish a homemade database.Conclusion:The ability of the homemade database was verified by analyzing the real pork samples, and the result was satisfactory.
Fabrication of Latex-based Nanofibers by Electrospinning
Authors: Zhou Chan-Juan , Chen Chen , Zhou Hong-yu , He Ji-Huan 
Published: September 2019

Background:
Natural latex has been widely used in medical gloves, gas masks and nipples
characterized by high elasticity, good film-forming performance and flexible film, but it is seldom used
in nanomaterials. Electrospinning is an effective technology for manufacturing microfibrous or nanofibrous
membranes. Latex-based nanofibers can be fabricated by electrospinning. Few relevant patents
to the topic have been reviewed and cited.

Methods:
The natural rubber latex and PVA solution were prepared for electrospinning in this study.

Results:
When the rubber tends to nano scales, the flexibility of natural rubber gets enhanced.
Additionally, the latex fluid can be used as an additive to improve mechanical property of nanofibers.

Conclusion:
The electrospinning rubber nanofibers shed a new light on rubber industry.
Influence of Nanocellulose Additive on the Film Properties of Native Rice Starch-based Edible Films for Food Packaging
Authors: Jeevahan Jeya , Chandrasekaran Manoharan 
Published: September 2019

Background & Objective:Starch-based edible films, which are transparent, odourless, biodegradable, tasteless, and semi-permeable to gases and food additives, have attracted the attention of the research community as the alternative food packaging materials to synthetic plastics. However, they pose poor water resistance and mechanical strength that should be improved for food packaging application. Few relevant patents to the topic have been reviewed and cited.Methods:Inclusion of nanoadditives in starch films can not only improve their mechanical and barrier properties but also can act as antimicrobial agent, oxygen scavenger, and biosensor. The present investigation is focussed on the effects of nanocellulose extracted from banana pseudostems on the film properties of rice starch-based edible films. Nanocellulose was extracted from dried banana pseudostems through isolation of cellulose and acid hydrolysis. Rice starch-based edible films were prepared through solution casting by adding nanocellulose of varying concentrations (0%, 2%, 4%, 6%, 8% & 10%).Results:The film properties, such as Water Vapour Permeability (WVP), mechanical strength (tensile strength, Young's modulus and percentage of elongation), film solubility in water and film colour, were determined. The test results were discussed and the effects of nanocellulose additives were studied.Conclusion:From the results, it was clear that the addition of nanocellulose had improved the film properties, making the rice starch-based edible films a promising choice for food packaging applications.
Cytotoxicity Evaluation of Dimethoxy and Trimethoxy Indanonic Spiroisoxazolines Against Cancerous Liver Cells
Authors: Abolhasani Ahmad , Heidari Fatemeh , Noori Somayeh , Mousavi Shokoufeh , Abolhasani Hoda 
Published: September 2019

Background:
3'-(3,4-dimethoxyphenyl)-4'-(4-(methylsulfonyl)phenyl)-4'H-spiro
[indene-2,5'-isoxazol]-1(3H)-one and 4'-(4-(methylsulfonyl)phenyl)-3'-(3,4,5-trimethoxyphenyl)-
4'H-spiro[indene-2,5'-isoxazol]-1(3H)-one compounds containing indanonic spiroisoxazoline
core are widely known for their antiproliferative activities and investigation of
tubulin binding modes.

Objective:
To evaluate the cytotoxicity effect of Dimethoxy and Trimethoxy Indanonic Spiroisoxazolines
against HepG2 cancerous liver cell line and to perform a comparison with
other known anti-liver cancer drugs.

Methods:
The evaluation of cytotoxicity of dimethoxy and trimethoxy indanonic spiroisoxazoline
compounds, Oxaliplatin, Doxorubicin, 5-fluorouracil and Cisplatin against HepG2
(hepatocellular liver carcinoma) cell line has been performed using MTT assay and analyzed
by GraphPad PRISM software (version 8.0.2).

Results:
Potent cytotoxicity effects against HepG2 cell line, comparable to Cisplatin (IC50=
0.047±0.0045 µM), Oxaliplatin (IC50= 0.0051µM), Doxorubicin (IC50= 0.0014µM) and 5-
fluorouracil (IC50= 0.0089 µM), were shown by both dimethoxy (IC50= 0.059±0.012 µM)
and trimethoxy (IC50= 0.086±0.019 µM) indanonic spiroisoxazoline compounds.

Conclusion:
In vitro biological evaluations revealed that dimethoxy and trimethoxy indanonic
spiroisoxazoline compounds are good candidates for the development of new anti-liver
cancer agents.
Adherence to Electronic Health Tools Among Vulnerable Groups: Systematic Literature Review and Meta-Analysis
Authors: Arsenijevic Jelena , Tummers Lars , Bosma Niels 
Published: September 2019

Background
Electronic health (eHealth) tools are increasingly being applied in health care. They are expected to improve access to health care, quality of health care, and health outcomes. Although the advantages of using these tools in health care are well described, it is unknown to what extent eHealth tools are effective when used by vulnerable population groups, such as the elderly, people with low socioeconomic status, single parents, minorities, or immigrants.

Objective
This study aimed to examine whether the design and implementation characteristics of eHealth tools contribute to better use of these tools among vulnerable groups.

Methods
In this systematic review, we assessed the design and implementation characteristics of eHealth tools that are used by vulnerable groups. In the meta-analysis, we used the adherence rate as an effect size measure. The adherence rate is defined as the number of people who are repetitive users (ie, use the eHealth tool more than once). We also performed a meta-regression analysis to examine how different design and implementation characteristics influenced the adherence rate.

Results
Currently, eHealth tools are continuously used by vulnerable groups but to a small extent. eHealth tools that use multimodal content (such as videos) and have the possibility for direct communication with providers show improved adherence among vulnerable groups.

Conclusions
eHealth tools that use multimodal content and provide the possibility for direct communication with providers have a higher adherence among vulnerable groups. However, most of the eHealth tools are not embedded within the health care system. They are usually focused on specific problems, such as diabetes or obesity. Hence, they do not provide comprehensive services for patients. This limits the use of eHealth tools as a replacement for existing health care services.
A Smartphone App Designed to Empower Patients to Contribute Toward Safer Surgical Care: Community-Based Evaluation Using a Participatory Approach
Authors: Russ Stephanie , Latif Zahira , Hazell Ahmarah Leah , Ogunmuyiwa Helen , Tapper Josephine , Wachuku-King Sylvia , Sevdalis Nick , Ocloo Josephine 
Published: September 2019

Background
MySurgery is a smartphone app designed to increase patient and carer involvement in behaviors that contribute toward safety in surgical care.

Objective
This study presents a pilot evaluation of MySurgery in which we evaluated surgical patients’ perceptions of the app in terms of its content, usability, and potential impacts on communication and safety.

Methods
A participatory action research (PAR) approach was used to formulate a research steering group consisting of 5 public representatives and 4 researchers with equal decision-making input. Surgical patients were recruited from the community using multiple approaches, including Web based (eg, social media, recruitment websites, and charitable or voluntary organizations) and face to face (via community centers). Participants referred to MySurgery before, during, and after their surgery and provided feedback via an embedded questionnaire and using reflective notes.

Results
A diverse mix of 42 patients took part with good representation from 2 “seldom heard” groups: those with a disability and those from a black, Asian, or minority ethnic group. Most were very supportive of MySurgery, particularly those with previous experience of surgery and those who felt comfortable to be involved in conversations and decisions around their care. The app showed particular potential to empower patients to become involved in their care conversations and safety-related behaviors. Perceptions did not differ according to age, ethnicity, or length of hospital stay. Suggestions for improving the app included how to make it more accessible to certain groups, for example, those with a disability.

Conclusions
MySurgery is a novel technology-driven approach for empowering patients to play a role in improving surgical safety that seems feasible for use within the United Kingdom’s National Health Service. Adopting a PAR approach and the use of a diversity strategy considerably enhanced the research process in terms of gaining diverse participant recruitment and patient and public involvement. Further testing with stakeholder groups will follow.
“Positive Peers”: Function and Content Development of a Mobile App for Engaging and Retaining Young Adults in HIV Care
Authors: Step Mary M , McMillen Smith Jennifer , Kratz Joshua , Briggs Julia , Avery Ann 
Published: September 2019

Background
Although treatment for HIV infection is widely available and well tolerated, less than 30% of adolescents and young adults living with HIV infection achieve stable viral suppression. Mobile technology affords increased opportunities for young people living with HIV to engage with information, health management tools, and social connections that can support adherence to treatment recommendations and medication. Although mobile apps are increasingly prevalent, few are informed by the target population.

Objective
The objective of this study was to describe the “Positive Peers” app, a mobile app currently being evaluated in a public hospital in the Midwestern United States. Formative development, key development strategies, user recruitment, and lessons learned are discussed in this paper.

Methods
“Positive Peers” was developed in collaboration with a community advisory board (CAB) comprising in-care young adults living with HIV and a multidisciplinary project team. Mobile app functions and features were developed over iterative collaborative sessions that were tailored to the CAB members. In turn, the CAB built rapport with the project team and revealed unique information that was used in app development.

Results
The study was funded on September 1, 2015; approved by the MetroHealth Institutional Review Board on August 31, 2016; and implemented from October 11, 2016, to May 31, 2019. The “Positive Peers” mobile app study has enrolled 128 users who reflect priority disparity population subgroups. The app administrator had frequent contact with users across app administration and study-related activities. Key lessons learned from the study include changing privacy concerns, data tracking reliability, and user barriers. Intermediate and outcome variable evaluation is expected in October 2019.

Conclusions
Successful development of the “Positive Peers” mobile app was supported by multidisciplinary expertise, an enthusiastic CAB, and a multifaceted, proactive administrator.
Immersive Virtual Reality in Health Care: Systematic Review of Technology and Disease States
Authors: Snoswell Aaron J , Snoswell Centaine L 
Published: September 2019

Background
Immersive virtual reality (IVR) presents new possibilities for application in health care. Health care professionals can now immerse their patients in environments to achieve exposure to a specific scene or experience, evoke targeted emotional responses, inspire, or distract from an experience occurring in reality.

Objective
This review aimed to identify patient-focused applications for head-mounted IVR for acute treatment of health conditions and determine the technical specifications of the systems used.

Methods
A systematic review was conducted by searching medical and engineering peer-reviewed literature databases in 2018. The databases included PubMed, EMBASE, Cumulative Index to Nursing and Allied Health Literature, Association for Computing Machinery, Institute of Electrical and Electronics Engineers, Scopus, and Web of Science. Search terms relating to health and IVR were used. To be included, studies had to investigate the effectiveness of IVR for acute treatment of a specific health condition. IVR was defined as a head-mounted platform that provides virtual and auditory immersion for the participant and includes a minimum of 3 degrees of orientation tracking. Once identified, data were extracted from articles and aggregated in a narrative review format.

Results
A total of 58 studies were conducted in 19 countries. The studies reported IVR use for 5 main clinical areas: neurological and development (n=10), pain reduction through distraction (n=20), exposure therapy for phobias (n=9), psychological applications (n=14), and others (n=5). Studies were primarily feasibility studies exploring systems and general user acceptance (n=29) and efficacy studies testing clinical effect (n=28).

Conclusions
IVR has a promising future in health care, both in research and commercial realms. As many of the studies examined are still exploring the feasibility of IVR for acute treatment of health conditions, evidence for the effectiveness of IVR is still developing.
Factores edafoclimáticos en la producción y calidad del pasto Saboya (Holcus lanatus L.) en el Altiplano de Nariño
Authors: Apráez Edmundo , Gálvez Arturo , Apraez Julian 
Published: September 2019

La ganadería de leche en el departamento de Nariño depende en gran medida de la oferta forrajera cuya calidad nutritiva y producción se ven afectadas principalmente por las condiciones climáticas. El objetivo de esta investigación fue establecer la incidencia de los factores edafoclimáticos en la producción y calidad del pasto Saboya (Holcus lanatus L.) en el Altiplano de Nariño. El estudio se realizó en tres zonas: zona 1) en tres localidades del municipio de Guachucal, entre 3050-3300 msnm; zona 2) tres del municipio de Ipiales, entre 2800-3049 msnm; zona 3) tres del municipio de Pasto, entre 2500-2650 msnm. Se muestrearon parcelas con pasto Saboya (Holcus lanatus L.) sin laboreo, donde se midieron variables climáticas, agronómicas, edáficas y bromatológicas, con el fin de determinar el grado de correlación entre ellas. Los resultados cuantitativos se sometieron a un Análisis Multivariado de Componentes Principales (ACP) y los cualitativos a un Análisis de Correspondencias Múltiples (ACM). Se concluyó que para obtener los mejores rendimientos del pasto Saboya (H. lanatus) a alturas entre los 2800-3049 msnm, se necesita de un suelo suelto, materia orgánica de 5-6% y un pH de 6 a 7. Además, se determinó que H. lanatus crece bien a una temperatura de 10ºC, humedad relativa del 83%, precipitación anual de 800 a 900 mm y una luminosidad de 25 klx. Entre 3050-3300 msnm, se requiere de un suelo suelto, materia orgánica superior al 10% y pH entre 5 y 6. El pasto se adapta bien a una temperatura de 10 a 12ºC, humedad relativa del 86,28% y precipitación pluvial de 923 mm anuales.
MODEL KURIKULUM PENDIDIKAN ISLAM MULTIKULTURAL DI PONDOK PESANTREN MODERN ISLAM ASSALAM SURAKARTA
Authors: Aly Abdullah 
Published: September 2019

This research aims to: (1) investigate the curriculum planning of Assalaam Modern Islamic Boarding School Surakarta (henceforth MIBS) and its multicultural values; (2) understand the implementation of Assalaam MIBS curriculum and its multicultural values; (3) reveal the curriculum evaluation of Assalaam MIBS and its multicultural values; and (4) search a model of curriculum development for multicultural Islamic Boarding Schools. This research produces 4 find- ings. First, closely investigated from multicultural perspectives, the curriculum planning of Assalaam MIBS includes both multicultural values (democratic and justice values) and antimulticultural values (discrimination and injustice values). Second, in the curriculum implementation, both multicultural and antimulticultural values are exposed to students. While the values of democracy, solidarity, togetherness, love, forgiveness, peace and tolerance are embedded in the learning materials, activities, and evaluation, the values of discrimination and injustice are found in the learning references, available only for special service program as opposed to regular programs. Third, the curriculum evaluation contains multicultural values such as democracy, peace, tolerance, and togetherness particularly embedded in the processes and product of curriculum evaluation. On the other hand, conflict, hegemony and domination values are found in the interac- tion among students in daily school environments. Fourth, the model curriculum of multicultural Islamic Boarding School needs to consider three aspects: (1) the planning of the multicultural Islamic boarding school curriculum is determined by its process and product; (2) the implementation of the multicultural Islamic Boarding school curriculum is determined by the textbooks that contain multicultural values; learning strategies that stimulate students’ active participation in democratic and interesting learning activities; and evaluation of contextual and comprehensive learning results by making use of oral and written tests, portfolios, and assignments; and (3) the evaluation of the multicultural Islamic Boarding School curriculum is determined by its process and product.
KADAR LOGAM BERAT Pb (TIMBAL) SUSU KAMBING YANG DIBERI PAKAN SILASE LIMBAH SAYURAN
Authors: Falahudin Aaf , Rahmah U.I.L. 
Published: September 2019

The aim of this research is to get information of heavy metal content of Pb in goat milk fed with vegetables waste silage which is safe to be consumed by society. The experiments were carried out by using 16 pregnant 2 - 2,5 years old goat who were treated until the mother was lactated. The experimental design used was Completely Randomized Design with 4 treatments and 4 replications. The treatments applied were as follows: T0 = 100% forage (mixture of grass and legume), T1 = 80% forage + 20% vegetables waste silage, T2 = 60% forage + 40% silage vegetables waste, and T3 = 40% forage + 60% waste silage vegetables. The experiment was conducted for 5 months. The research results show that the feed silage vegetables waste very real produce milk production daily higher than the control of grass. The provision of silage vegetables waste very real produce metal Pb levels higher than control and be above threshold SNI 3141.1: 2011. So that it can be concluded that the silage vegetables waste not advisable done by farmers due to metal Pb in goat milk is still not safe to be consumed. Keywords : Silage, Vegetables Waste, Pb, Goat Milk.
STUDI KASUS TINGKAT INFEKSI CACING PADA PETERNAKAN KAMBING BOER DI KABUPATEN BANYUMAS
Authors: Indradji Mohandas , Yuwono Endro , Indrasanti Diana , Samsi Muhamad , Sufriyanto Sufriyanto , R. Asep Herlan , Herdiana Budi 
Published: September 2019

The worm infections can cause a decrease in livestock productivity, were in the form of a decrease in body weight, milk production, growth restriction, decrease immunity to disease, even death. Research on worm disease in Boer goats aims to determine the infection rate of Nematodiasis and Trematodiasis in goats with various age levels, young and adult age groups. This research method is survey with sampling technique is sampling by the judgment. The data analysis of the research was prevalence study and Chi-Square analysis (X2). The examination of worm eggs in feces on the research used centrifuge method. The results of examination on 30 samples of Boer goats showed that 93.33% of Boer goats were infected by Nematodes and 13.33% of Boer goats were infected by Trematoda. Infection rates of Nematodes and Trematoda were not showed any significant differences between the two groups. The low level of Trematodiasis in Boer goats indicates that Boer goats in Banyumas district are resistant to Trematoda worm infections. Keywords: Boer Goats, Centrifuge Method, Chi-Square Analysis, Infection Rate, Worm Infection
PENGARUH IMBANGAN PROTEIN DAN ENERGI TERHADAP EFISIENSI PENGGUNAAN RANSUM PADA DOMBA GARUT BETINA
Authors: Ayuningsih Budi , Hernaman Iman , Ramdani Diky , Siswoyo Siswoyo 
Published: September 2019

This research aimed to study the effect of protein and energy on Diet Use Efficiency of female Garut sheep. Four different treatments diets of different protein to TDN (energy) ration such as R1=11.53%:63.13%; R2=10.78%:70.06%; R3=13.54%:63.18%; and R4=13.67%:69.18% were allocated to 20 heads of female Garut sheep with 7-8 months old and average body weight 15.72 ± 1.33 kg. Completely randomized design was used and collected data was analyzed with Duncan’s test. The results showed that highest diet use efficiency and protein consumption (P<0.05) were seen in R4 treatment, 13.09% and 94.04 g/day. Meanwhile, TDN consumption did not have any different among R4 (480.23 g/day), R2 (474.80 g/day), and R1 (446.77 g/day) but they were higher (P<0.05) than R3 (370.87 g/day). In other hand, TDN digestibility of R2 and R3 were higher than R1 and R3. In conclusion, protein to TDN ratio of 13.67%:69.18% resulted highest diet use efficiency. Keywords: Female Garut Sheep, Digestibility, Protein, Total Digestible Nutrient