bluuebunny/crossref_metadata_2025_split huggingface dataset:
Significant Induction of Soluble TNFR2 Compared with TNFR1 in Serum Samples of HIV Patients with or without Antiretroviral Medication
Authors: Sarfo Bismark , Haile Zelalem Teka , Deletsu Selase , Mensah Eric Akpanja , Bonney Evelyn Yayra 
Published: October 2018

Background:
Tumor necrosis factor and its receptors (sTNFR1 and sTNFR2) have
been implicated in many infectious diseases. Identification of the key receptor (sTNFR1 or
sTNFR2) which drives the immunopathogenesis of HIV infection is crucial in developing
adjunctive therapy for HIV.

Objective:
This study determined the expression levels of sTNFR1 and sTNFR2 in antiretroviral
therapy (ART) - experienced and naïve HIV patients.

Methods:
A total of 40 HIV patients comprising 30 with ART and 10 without ART were enrolled
from the Pantang Hospital located in the Greater Accra Region of Ghana for data and blood collection.
Serum concentrations of sTNFR1 and sTNFR2 were determined by ELISA. Mann-
Whitney U test was used to examine differences in serum levels of sTNFR1 and sTNFR2 between
patients on ART and ART naïve patients. Wilcoxon Signed-Rank test was performed to determine
the difference between sTNFR1 and sTNFR2, and Kruskal Wallis test was conducted to compare
the effect of different antiretroviral drugs on the levels of sTNFR1 and sTNFR2. P< 0.05 was considered
statistically significant.

Results:
A Wilcoxon Signed-Ranks Test indicated serum levels of sTNFR2 was statistically significantly
higher than sTNFR1 (Z=-5.51; p0.05 was considered0.001). Levels of sTNFR1 and sTNFR2 did not differ
by ART status U =91.00 (Z = -1.84), p = 0.065 and U = 131.50 (Z = -0.58, p =0.560), respectively.
There were not significant differences in levels of TNFR2 H(2) = 1.86, p=0.395 and
sTNFR1 (H (2) = 4.37, p=0.113 across different ART combinations.

Conclusion:
Compared to sTNFR1, the level of sTNFR2 is significantly increased during HIV
infection irrespective of ART status. The high sTNFR2 level is not associated with antiretroviral
drugs and may be another potential target for therapeutic development. This is the first study of
sTNFRs in African population.
Distribution and Characteristics of Intrathoracic Lymphadenopathy in TB/HIV Co-Infection
Authors: Mehrian Payam , Doroudinia Abtin , Shams Moghadaseh , Alizadeh Niloufar 
Published: October 2018

Background:
Intrathoracic Lymphadenopathy (ITLN) in Human Immunodeficiency
Virus (HIV) infected patients may have various etiologies and prognoses. Etiologies of ITLN can
be distinguished based on the distribution of enlarged lymph nodes. Sometimes tuberculosis (TB)
is the first sign of underlying HIV infection.

Objective:
We sought to determine ITLN distribution and associated pulmonary findings in
TB/HIV co-infection using Computed Tomography (CT) scan.

Methods:
In this retrospective, observational, cross-sectional study, chest CT scans of 52 patients
with TB/HIV co-infection were assessed for enlarged intrathoracic lymph nodes (>10 mm in short
axis diameter), lymphadenopathy (LAP) distribution, calcification, conglomeration, the presence
of hypodense center and associated pulmonary abnormalities. LAP distribution was compared in
TB/HIV co-infection with isolated TB infection.

Results:
Mediastinal and/or hilar LAP were seen in 53.8% of TB/HIV co-infection patients. In all
cases, LAP was multinational. The most frequent stations were right lower paratracheal and subcarinal
stations. Lymph node conglomeration, hypodense center and calcification were noted in
25%, 21.4% and 3.5% of patients, respectively. LAP distribution was the same as that in patients
with isolated TB infection except for the right hilar, right upper paratracheal and prevascular stations.
All patients with mediastinal and/or hilar adenopathy had associated pulmonary abnormalities.

Conclusion:
All patients with TB/HIV co-infection and mediastinal and/or hilar adenopathy had
associated pulmonary abnormalities. Superior mediastinal lymph nodes were less commonly affected
in TB/HIV co-infection than isolated TB.
Singular Values Decomposition and Lifting Wavelet Transform for Speech Signal Embedding into Digital Image
Authors: Talbi Mourad , Bouhlel Med Salim 
Published: October 2018

Background:
In this paper, we propose a secure image watermarking technique which is applied
to grayscale and color images. It consists in applying the SVD (Singular Value Decomposition) in the Lifting
Wavelet Transform domain for embedding a speech image (the watermark) into the host image.

Methods:
It also uses signature in the embedding and extraction steps. Its performance is justified by
the computation of PSNR (Pick Signal to Noise Ratio), SSIM (Structural Similarity), SNR (Signal to
Noise Ratio), SegSNR (Segmental SNR) and PESQ (Perceptual Evaluation Speech Quality).

Results:
The PSNR and SSIM are used for evaluating the perceptual quality of the watermarked image
compared to the original image. The SNR, SegSNR and PESQ are used for evaluating the perceptual
quality of the reconstructed or extracted speech signal compared to the original speech signal.

Conclusion:
The Results obtained from computation of PSNR, SSIM, SNR, SegSNR and PESQ show
the performance of the proposed technique.
Pengembangang m-learning untuk mendukung kemandirian dan hasil belajar mata pelajaran Geografi
Authors: Rahmawati Erni Mardliyani , Mukminan Mukminan 
Published: October 2018

Penelitian ini bertujuan: (1) menghasilkan m-learning yang dapat digunakan pada pembelajaran mata pelajaran geografi bagi peserta didik kelas X SMA, (2) menghasilkan m-learning yang layak untuk mata pelajaran geografi, (3) mengetahui keefektifan m-learning untuk mata pelajaran geografi, dan (4) mengetahui pengaruh m-learning dalam mendukung kemandirian dan hasil belajar peserta didik. Jenis penelitian ini adalah penelitian dan pengembangan (R&D). Hasil penelitian menunjukkan bahwa (1) m-learning dibuat dengan menggunakan adobe flash cs 5.5. m-learning dikembangkan untuk pokok bahasan Hidrosfer; (2) m-learning telah memenuhi kriteria dan dinyatakan layak sebagai media pembelajaran berdasarkan validasi dengan kategori “baik”; (3) keefektifan pembelajaran geografi lebih baik dengan menggunakan m-learning dibuktikan dengan adanya ketuntasan belajar pada kelas eksperimen; (4) m-learning signifikan mendukung kemandirian dan hasil belajar peserta didik.Kata kunci: m-learning, geografi, kemandirian DEVELOPING MOBILE LEARNING TO SUPPORT INDEPENDENCE AND LEARNING OUTCOMES IN HIGH SCHOOL GEOGRAPHY LESSONAbstractThe research is aimed at: (1) producing m-learning that can be used in teaching geography subjects for students of class X SMA, (2) producing proper m-learning for Geography lesson, (3) finding out the effectiveness of m-learning in Geography lesson, and (4) detecting the m-learning effect in Geography lesson to support independent and outcomes of learning for students. This is a Research and Development type of research. The results show that: (1) m-learning designed with adobe flash cs 5.5 application is suitable for Hidrosfer lesson topic; (2) m-learning for Geography lesson has met the criteria and considered to be a proper learning media due to the fact that the validation categorizes it as “good”; (3) geography better learning effectiveness by using m-learning is evidenced by student’s mastery learning in the experimental class, and (4) m-learning geography subjects support the independence and learning outcomes of students.Keywords: m-learning, geography, independent learning
Pengembangan media pembelajaran ekonomi mikro interaktif berkarakter pembelajaran hybrid
Authors: Soejoto Ady , Harti Harti , Hakim Luqman , Ghofur Muhammad Abdul 
Published: October 2018

Masih sedikitnya pilihan media yang dapat digunakan dalam pembelajaran hybrid mendorong pentingnya mengembangkan media pembelajaran interaktif yang sesuai dengan kebutuhan mahasiswa Universitas Negeri Surabaya khususnya untuk Mata Kuliah Teori Ekonomi Mikro. Oleh karena itu, penelitian ini bertujuan untuk mengembangkan media pembelajaran ekonomi mikro interaktif berkarakter pembelajaran hybrid. Metode pengembangan media ini menggunakan model pengembangan ADDIE dengan target output yaitu aplikasi media pembelajaran Ekonomi Mikro interaktif yang bisa dijalankan di perangkat Android dan Windows. Subjek penelitian ini adalah pembelajaran pada Program Studi Pendidikan Ekonomi Pascasarjana Unesa. Setelah dilakukan analisis sampai pengembangan selama sekitar 4 bulan dihasilkan output aplikasi media pembelajaran interaktif ini yang bisa dijalankan pada sistem operasi Windows dan Android untuk diterapkan pada pembelajaran hibrid komplementer mata kuliah Teori Ekonomi Mikro. Media pembelajaran ini masih sangat mungkin untuk dikembangkan lagi, baik dari sisi materi, tampilan format maupun assessmen.Kata kunci: pembelajaran hybrid, media pembelajaran, interaktif DEVELOPING MICROECONOMICS INTERACTIVE LEARNING MEDIA WITH HYBRID LEARNING CHARACTERISTICSAbstractThis study aims to develop a hybrid micro-economic interactive learning media, because of the minimum of media selection that can be used in hybrid learning was less to encourages learning process. This development also important to accordance with the needs of students in the State University of Surabaya, especially for the Course of Microeconomic Theory. This method of media development using the ADDIE development model with the target output is an interactive Micro-learning learning media applications that can run on Android and Windows devices. After the development process for about 4 months generated the output of this interactive learning media applications that can run on Windows and Android operating system to apply to complementary hybrid learning subjects Micro Economic Theory. Learning media is still very likely to be developed again, both in terms of materials, display formats and assessment.Keywords: hybrid learning, learning media, interactive
The Hoax Phenomenon in Indonesian Society: Observing Anti-Diversity Memes since 2014
Authors: Salam Aprinus 
Published: October 2018

This article seeks to explain whether anti-diversity hoaxes that become viral on mass media disrupt the institutional memory of kebhinekaan (diversity) in Indonesian society. The spreading of hoaxes is a phenomenon of postmodern society, and thus this study uses a post-structural approach, in this case, using the theory of Slavoj Zizek. Memes used as data mostly deal with themes of nationality, ethnicity, and religion. The results of this study show that anti-diversity hoaxes are used for short-term purposes (power politics), so they do not intervene the institutional memory of Indonesian society and its belief in diversity.
Ancaman Masuknya Virus Penyakit Mulut dan Kuku Melalui Daging Ilegal di Entikong, Perbatasan Darat Indonesia dan Malaysia
Authors: Silitonga Risma JP 
Published: October 2018

This study was aimed to analyze the risk of FMD virus to enter Indonesia by the presence of illegal meat at Entikong, a borderland between Indonesia and Malaysia. The primary datas were collected using questionnaires method to collect expertise, in-depth interviews, and direct field observations. Secondary datas were obtained from scientific publications and articles or unpublished datas (statistics, goverment documents and reports). The respondents were choosen by purposive sampling. The circulating illegal meat was possibly originate fromdifferent countries, including FMD-endemic countries/zones such as Peninsular Malaysia, Thailand, India and even unidentified countries/zones according to our respondends. The types of illegal meat such as frozen deglanded bonein-meat and frozen deglanded offal that enter Entikong carry the risk of becoming a source of FMD infection. Based on the entry route, delivery frequency, and meat volume, ilegal meat was possibly also entered into Indonesia using non-vehicular transportation. These conditions indicated that the entrance of illegal meat could pose risk of the FMD virus entry to Indonesia, especially at the borderland between Indonesia and Malaysia at Entikong. It is highly recommended to apply strict inspection at the border entraces and increase collaboration with related institutions to prevent the entrance of illegal meat and to reduce the entry risk of FMD virus.
Respon Imun Mencit terhadap Protein 24 dan 71 kDa Toxocara vitulorum dalam Membentuk Antibodi dan Protektifitasnya terhadap Infeksi Buatan
Authors: Atma Candra Dwi , Kusnoto Kusnoto , Aksono HP. Eduardus Bimo 
Published: October 2018

This study aimed to get 24 and 71 kDa protein of T. vitulorum that have a high antigenicity and imunogenicity on ELISA and to get the protein which able to protect mice against artificial infection of L2 T. vitulorum. This study using mice Balb/c aged 6 to 8 weeks. Proteins isolated were 24 and 71 kDa. Proteins 24, 71 kDa and intestinal homogenates immunized in mice with the addition of adjuvant (1: 1) for 3 times with period of 2 weeks. Two weeks after the last booster, serum drawn from mice tested by Indirect ELISA to determine the value of optical density (OD). The next stage, mice were infected L2 with a dose of 10-17 larvae / g of body weight. The results showed the average OD value by ANOVA Factorial antigen P24 was not significantly different with antigen P71 T. vitulorum. Antigen 24 kDa and 71 kDa with different immunization, both were showed P0 significantly different with P1, P2 and P3. Based on percentage of L2 in the somatic tissue of mice, P0 were showed 79.1% of total number of L2 early infection, whereas the treatment of P1 were showed 0.04%, P2 and P3 showed as much as 0.02% and 0.04%. 24 and 71 kDa protein of T. vitulorum that have a high antigenicity and imunogenicity.
Análise da relação entre O3, NO e NO2 usando técnicas de regressão linear múltipla.
Authors: Souza Amaury De , Ikefuti Priscilla V , Garcia Ana Paula , Santos Debora A.S , Oliveira Soetania 
Published: October 2018

Análise e previsão de parâmetros de qualidade do ar são tópicos importantes da pesquisa atmosférica e ambiental atual, devido ao impacto causado pela poluição do ar na saúde humana. Este estudo examina a transformação do dióxido de nitrogênio (NO2) em ozônio (O3) no ambiente urbano, usando o diagrama de séries temporais. Foram utilizados dados de concentração de poluentes ambientais e variáveis meteorológicas para prever a concentração de O3 na atmosfera. Foi testado o emprego de modelos de regressão linear múltipla como ferramenta para a predição da concentração de O3. Os resultados indicam que o valor da temperatura e a presença de NO2 influenciam na concentração de O3 em Campo Grande, capital do Estado do Mato Grosso do Sul. Palavras-chave: Ozônio. Dióxido de nitrogênio. Séries cronológicas. Regressões. ANALYSIS OF THE RELATIONSHIP BETWEEN O3, NO AND NO2 USING MULTIPLE LINEAR REGRESSION TECHNIQUES.Abstract: Analysis and prediction of air quality parameters are important topics of current atmospheric and environmental research due to the impact caused by air pollution on human health. This study examines the transformation of nitrogen dioxide (NO2) into ozone (O3) in the urban environment, using the time series diagram. Environmental pollutant concentration and meteorological variables were used to predict the O3 concentration in the atmosphere. The use of multiple linear regression models was tested as a tool to predict O3 concentration. The results indicate that the temperature value and the presence of NO2 influence the O3 concentration in Campo Grande, capital of the State of Mato Grosso do Sul.Keywords: Ozone. Nitrogen dioxide. Time series. Regressions. ANÁLISIS DE LA RELACIÓN ENTRE O3, NO Y NO2 UTILIZANDO MÚLTIPLES TÉCNICAS DE REGRESIÓN LINEAL.Resumen: Análisis y previsión de los parámetros de calidad del aire son temas importantes de la actual investigación de la atmósfera y el medio ambiente, debido al impacto de la contaminación atmosférica sobre la salud humana. Este estudio examina la transformación del dióxido de nitrógeno (NO2) en ozono (O3) en el entorno urbano, utilizando el diagrama de series de tiempo. Las concentraciones de los contaminantes ambientales de datos y variables climáticas fueron utilizadas para predecir la concentración de O3 en la atmósfera. El uso de múltiples modelos de regresión lineal como herramienta para predecir la concentración de O3 se puso a prueba. Los resultados indican que el valor de la temperatura y la presencia de NO2 influyen en la concentración de O3 en Campo Grande, capital del Estado de Mato Grosso do Sul.Palabras clave: Ozono. Dióxido de nitrógeno. Series de tiempo. Regresiones.
Esthetic evaluation of facial cheek volume: A study using 3D stereophotogrammetry
Authors: Feng Jie , Yu Hongyou , Yin Yijia , Yan Yinqiu , Wang Zheng , Bai Ding , Han Xianglong 
Published: October 2018

ABSTRACT

Objectives:
To investigate the influence of cheek volume on facial esthetics judged by orthodontists and non-specialists.

Materials and Methods:
A 25-year-old female's natural and smiling face was captured by 3D stereophotogrammetry. Cheek volume of the 3D image was altered to different degrees three-dimensionally. For the natural and smiling face, seven groups of facial images were created: decreased grade I/II/III, increased grade I/II/III, and the original one. Thirty orthodontists and 30 nonspecialists were invited to perform esthetic evaluation of the original and transformed images using a questionnaire. Data were calculated with one-way analysis of variance (least significant difference test) and independent samples t test.

Results:
Compared to nonspecialists, orthodontists gave lower esthetic scores to the decreased grade III facial images (maximum deformation degree: 7.500 mm and 7.327 mm in natural and smiling face-oriented image groups, respectively). The decreased grade III facial images also received the highest age ranks. However, the increased grade III facial images received the lowest scores and highest age ranks from nonspecialists (maximum deformation degree: 6.994 mm and 5.300 mm in natural and smiling face-oriented image groups, respectively) (P &lt; .01).

Conclusions:
Orthodontists and nonspecialists showed different esthetic evaluation of varied cheek volume. The influence of cheek volume in orthodontic diagnostic analysis needs further consideration.
Foeniculum sanguineum Triano y A. Pujadas (Apiaceae) nueva especie del suroeste de la Región Mediterránea
Authors: Pujadas Salvà Antonio J. , Triano Muñoz Enrique , Anaya Josefa , Grande Manuel , Raposo César , Torres Pascual , Hernández Pilar 
Published: October 2018

Se describe Foeniculum sanguineum Triano & A. Pujadas, sp. nov., del suroeste de la Región Mediterránea (España y Marruecos). Para su caracterización se ha realizado el análisis morfológico, citológico, fitoquímico y molecular. Se ha llevado a cabo el studio comparativo con Foeniculum vulgare Mill. La nueva especie F. sanguineum se distingue principalmente por sus pétalos rojos, polen rosado en fresco y por su estilopodio rojo. Es una especie diploide (2n= 22). Se ha encontrado una alta proporción de óxido de limoneno y piperitenona (ausente en F. vulgare) en la composición de aceite esencial de los frutos secos de F. sanguineum y una elevada cantidad (aproximadamente 50%) de α-felandreno en sus raíces y tallos. El análisis filogenético se realizó utilizando las secuencias del espaciador transcrito interno de ADN ribosomal nuclear (ITS) y las secuencias del gen cloroplástico rbcL. El análisis ITS apoya la existencia de la nueva especie, al tiempo que revela la divergencia de secuencias tanto a nivel intraespecífico como a nivel interespecífico. La divergencia de secuencia encontrada en el gen cloroplástico, aunque reducida a un nucleótido, proporcionó apoyo adicional para la caracterización de la nueva especie, para la que se propone el nombre de Foeniculum sanguineum.
Diz Osteoartritinde İntraartiküler Hyalüronik Asit ve Tenoksikamın Ağrı ve Diz Eklem Fonksiyonları Üzerine Etkilerinin Karşılaştırılması
Authors: ÖZKILIÇ Recai , KURU Tolgahan , İPEK Serdar , KESKİN Ekrem , Işık Cengiz , KAYA Yasin Emre 
Published: October 2018

Amaç: Bu çalışmada gonartrozlu hastalarda intraartiküler
hyalüronik asit (HA) ve tenoksikam uygulanmasının eklem hareket açıklığı (EHA)
ve ağrı üzerine etkilerinin karşılaştırılması amaçlanmıştır.Hastalar
ve Yöntem: Bu çalışma prospektif,
randomize olmayan kontrollü ve tek kör olarak planlanmıştır. ACR (American College of Rheumatology)
kritelerine göre Grade II ve Grade III osteoartrit (OA) tanısı konulmuş 60
hasta çalışmaya ardışık olarak alındı. Hastalar iki gruba ayrılarak birinci gruba birer hafta arayla 3 doz
intraartiküler HA, diğer gruba ise tek doz intraartiküler tenoksikam
uygulandı. Grupların tedavi öncesi ve
sonrası VAS ve EHA değerleri karşılaştırıldı. Bulgular: HA Grubu’nda yer alan hastaların 20’si (%66.6) kadın, 10’u
(%33.3) erkekti ve bu hastaların yaş ortalaması 59.6 (yaş aralığı 45-75) yıl
idi. Tenoksikam Grubu'nda yer alan hastaların 24’ü (%80) kadın, 6’sı (%20)
erkekti ve bu grubun yaş ortalası 61.5 (yaş aralığı 45-75) yıl idi. Tedavi
sonrası her iki grupta da tedavi öncesine göre 1. Gün, 15. Gün, 1. ay, 2. ay ve
3. ay değerlerinde VAS, dizin fleksiyon ve ekstansiyon EHA’sında artış
saptanmıştır (p&lt;0.05). Gruplar arası değişim miktarları
karşılaştırıldığında, erken dönemde Tenoksikam Grubu’ndaki değişiklikler daha
belirgindi fakattedavi sonrası 3. ay değerlerinde iki grup açısından fark
saptanmadı (p&gt;0.05).

Sonuç: Grade 2-3 diz OA’li hastalarda intraartikuler HA ve
tenoksikam uygulamalarının etkin ve güvenilir yöntemler olduğu; fakat
tenoksikamın HA’ya göre erken dönemde ağrıyı azaltma ve EHA’yı arttırmada daha
etkili olduğu görüldü.
Analisis Kadar Logam Kadmium (Cd) dan Timbal (Pb) pada Sedimen Di Teluk Ambon Bagian Dalam
Authors: Male Yusthinus T , Malle Dominggus , Bijang Catherina Manukpadang , Fransina Eirene Grace , Seumahu Cecelia Anna , Dolaitery Lois Mikhal , Landu Sartika , Gaspersz Nelson 
Published: October 2018

The research about analysis of cadmium (Cd) and lead (Pb) metal content on sediment inner part of Ambon Bay has been done. Sampling point located at Dermaga Ferry Poka, PLTD Poka, Kate-kate, Waiheru, Lateri III, Passo dan PLTD Galala. The results of analyzed of sediment particle size inside the Ambon Bay showed 3 components were sand, gravel, and sludge, but the sediments was dominated by sludge sand. Analysis of Cd content showed that at 7 stations in Ambon Bay detected Cd metal with the highest concentration at 4th station of Waiheru village was 0,6640 mg/Kg and the lowest concentration at 3th station of Kate-kate village was 0,0980 mg/Kg. Meanwhile, the highest Pb content was 20,075 mg/kg at 4th station and the lowest was 5,755 mg/kg at 2nd station of PLN Poka. The content of elements composition of sediment are SiO2, K2O, P2O5, Fe2, BaO, NiO and Ga2O3 but Cd and Pb metal was not detected.
Kinetika Adsorpsi Zat Warna Metilen Biru Oleh Karbon Aktif Dari Kulit Kemiri (Aleurites moluccana (L) Willd)
Authors: Latupeirissa Jola , Tanasale Matheis F.J.D.P. , Musa Sigit Hardianto 
Published: October 2018

The adsorption of methylene blue dye by active carbon of hazelnut shell has been done. Through acquired active carbon composing process, where is the hazelnut shell at entry into furnace on temperature 350 for 2 hour, afterwards is cooled and at sieves by sieve 100 mesh. Then by the calsination process in furnace with temperature 450 one was streamed to gas N2 four 2 hours then characterized by X-ray diffraction (XRD) for carbon before activation. The next activated with KOH solution with a concentration 0f 50 four 5 hour, then dried in an ovenat 120℃ for 1 hour and thencharacterized. Weight of the solidacidity before and after activation consecutive (5.3848 x 10-3 dan 42.1554x 10-3) mol g-1. Isotherm adsorption of methylene blue dyes on active carbon was following the Freundlich isotherm. Adsorption kinetics of methylene blue dyes on active carbon in various concentration of hazelnut shell was controlled with temperature variety at 25 and 30 . The result showed that energy activation was kJ mol-1 and a value isg mg-1 menit-1. Adsorption mechanism of methylene blue dyes on active carbon at various concentration of hazelnut shell is chemical adsorption process.