bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cyclohexanehexone with Ultrahigh Capacity as Cathode Materials for Lithium‐Ion Batteries
Authors: Lu Yong , Hou Xuesen , Miao Licheng , Li Lin , Shi Ruijuan , Liu Luojia , Chen Jun 
Published: March 2019

AbstractOrganic carbonyl compounds show potential as cathode materials for lithium‐ion batteries (LIBs) but the limited capacities (<600 mA h g−1) and high solubility in electrolyte restrict their further applications. Herein we report the synthesis and application of cyclohexanehexone (C6O6), which exhibits an ultrahigh capacity of 902 mA h g−1 with an average voltage of 1.7 V at 20 mA g−1 in LIBs (corresponding to a high energy density of 1533 Wh kg−1
). A preliminary cycling test shows that C6O6 displays a capacity retention of 82 % after 100 cycles at 50 mA g−1 because of the limited solubility in high‐polarity ionic liquid electrolyte. Furthermore, the combination of DFT calculations and experimental techniques, such as Raman and IR spectroscopy, demonstrates the electrochemical active C=O groups during discharge and charge processes.
Embedding and Positioning of Two FeII4L4 Cages in Supramolecular Tripeptide Gels for Selective Chemical Segregation
Authors: Kieffer Marion , Garcia Ana M. , Haynes Cally J. E. , Kralj Slavko , Iglesias Daniel , Nitschke Jonathan R. , Marchesan Silvia 
Published: March 2019

AbstractAn unreported d,l‐tripeptide self‐assembled into gels that embedded FeII4L4 metal–organic cages to form materials that were characterized by TEM, EDX, Raman spectroscopy, rheometry, UV/Vis and NMR spectroscopy, and circular dichroism. The cage type and concentration modulated gel viscoelasticity, and thus the diffusion rate of molecular guests through the nanostructured matrix, as gauged by 19F and 1H NMR spectroscopy. When two different cages were added to spatially separated gel layers, the gel–cage composite material enabled the spatial segregation of a mixture of guests that diffused into the gel. Each cage selectively encapsulated its preferred guest during diffusion. We thus present a new strategy for using nested supramolecular interactions to enable the separation of small molecules.
Diastereo‐ and Enantioselective Access to Stereotriads through a Flexible Coupling of Substituted Aldehydes and Alkenes
Authors: Li Jing , Preinfalk Alexander , Maulide Nuno 
Published: March 2019

AbstractA flexible redox‐neutral coupling of aldehydes and alkenes enables rapid access to stereotriads starting from a single stereocenter with perfect levels of enantio‐ and diastereoselectivity under mild conditions. The versatility of the method is highlighted by the installation of heteroatoms along the tether, which enables a route to structurally diverse building blocks. The formal synthesis of (+)‐neopeltolide further demonstrates the synthetic utility of this approach.
Polymeric Carbon Nitride/Reduced Graphene Oxide/Fe2O3: All‐Solid‐State Z‐Scheme System for Photocatalytic Overall Water Splitting
Authors: Pan Zhiming , Zhang Guigang , Wang Xinchen 
Published: March 2019

AbstractThe charge transfer between hydrogen evolution photocatalysts (HEPs) and oxygen evolution photocatalysts (OEPs) is the rate‐determining step that controls the overall performance of a Z‐scheme water‐splitting system. Here, we carefully design reduced graphene oxide (RGO) nanosheets for use as solid‐state mediators to accelerate the charge carrier transfer between HEPs (e.g., polymeric carbon nitride (PCN)) and OEPs (e.g., Fe2O3), thus achieving efficient overall water splitting. The important role of RGO could also be further proven in other PCN‐based Z‐systems (BiVO4/RGO/PCN and WO3/RGO/PCN), illustrating the universality of this strategy.
Safe Medication Management at Ambulatory Surgery Centers
Authors: Ubaldi Kerri 
Published: March 2019

AbstractSafe medication management is an important aspect of preventing patient harm. Medication management in the ambulatory setting can be complicated because of state and federal regulations and requirements imposed by accrediting organizations. Ambulatory surgery center leaders should review their medication management programs internally to assess their comprehensiveness in terms of efficiency, meeting regulatory requirements, and keeping patients safe. Partnering with a pharmacist or pharmacy consultant can be a useful way to address challenges with proper medication management. Perioperative medication use and administration, postoperative pain management, medication disposal, staff member and physician education, proper documentation in the medical record by all disciplines, pharmacoeconomics, pharmacy compounding needs, and controlled medication management and oversight are all important components of this segment of care. Ensuring that medication management programs at ambulatory surgery centers meet all regulatory and patient safety requirements is essential.
The Role of Electronic Documentation in Ambulatory Surgery Centers
Authors: Geier Ann , Smith Daren 
Published: March 2019

AbstractAmbulatory surgery centers (ASCs) have been slow to adopt electronic documentation (ie, electronic health records [EHRs]) compared with other types of health care organizations. However, recent developments, including documentation requirement changes, storage and security needs, and competition for physicians and perioperative personnel, have spurred greater interest in this technology. Electronic documentation systems can help meet the clinical, financial, operational, and regulatory needs of ASCs. Perioperative nurses should be involved in ensuring their facilities choose electronic documentation systems that meet objectives for all areas of their ASCs’ operations. This article examines the benefits of EHRs and their use in ASCs today and in recent history, explains significant factors that encourage the adoption of electronic documentation by ASCs, and provides guidance on how to invest in an EHR system more effectively.
Reprocessing Single‐Use Devices in the Ambulatory Surgery Environment
Authors: Ubaldi Kerri 
Published: March 2019

AbstractReprocessing single‐use surgical supplies and devices is an option for hospitals and ambulatory surgery centers (ASCs). The US Federal Government has recognized the practice since 2000, and regulatory oversight has increased dramatically since that time. Reprocessing single‐use devices is safe when personnel use approved methods, and health care facilities can experience significant cost savings by participating in this type of initiative. This article explores reprocessing and its benefits in ASCs, including a review of the oversight that the US Food and Drug Administration currently has for reprocessing and a discussion of the results of studies pertaining to this practice. The article also describes some issues that ASC leaders need to be aware of when considering the implementation of a reprocessing program. Single‐use device reprocessing can be an effective tool for ASC leaders to conserve and manage resources.
Highly stretchable, ionic conductive and self‐recoverable zwitterionic polyelectrolyte‐based hydrogels by introducing multiple supramolecular sacrificial bonds in double network
Authors: Diao Wenjing , Wu Linlin , Ma Xiaofeng , Zhuang Zhenzhen , Li Shuai , Bu Ximan , Fang Ying 
Published: March 2019

ABSTRACTZwitterionic hydrogels have been explored for applications in electrochemical devices very recently due to their high water retention ability and interesting electrochemical properties. The use of zwitterionic hydrogels in devices requires them tough and recoverable or healable from fatigue damage. Herein, a double network zwitterionic hydrogel contains a reversible noncovalent interaction crosslinked polyvinyl alcohol (PVA) first network, together with a covalent/noncovalent hybrid crosslinked acrylamide and sulfobetaine methacrylate copolymer (P(AM‐co‐SBMA)) second network, was fabricated by a simple two‐steps methods of copolymerization and freezing/thawing. The reversible hydrogen bonds, crystalline domain, and electrostatic interactions in the double networks work as sacrificial bonds to dissipate energy and toughen the materials when hydrogel deforms. The broken bonds can reform upon unloading endowing the recovery of hydrogels' properties with the assistance of the elastic covalent network. The optimal hydrogels are highly stretchable (fracture strain 970%), tough (fracture toughness 693 kJ m−3), rapidly recoverable (65% toughness recovery and 75% stiffness recovery after resting 5 min at room temperature) and with widely tunable mechanical properties by multibond crosslinking. Meanwhile, the zwitterionic counterions of SBMA moieties endow the tough and recoverable hydrogels extremely high intrinsic ionic conductivities (7.49 S m−1) at room temperature. This work not only provides a simple strategy for fabricating tough and recoverable zwitterionic hydrogels but also demonstrates multifunctional properties of the zwitterionic hydrogels, which possess a great potential to fulfill flexible devices applications. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47783.
Achieving High‐Temperature Stability of Metastable α‐MoC1‐x by Suppressing Phase Transformation with Mounted Atoms for Lithium Storage Performance
Authors: Gao Cheng , Meng Tao , Yang Pei , Guo Wei , Cao Minhua 
Published: March 2019

AbstractDespite a significant advancement in preparing metastable materials, one common problem is the strict and precious reaction conditions due to their metastable structures. Herein, we achieved the preparation of high‐temperature stabilized metastable α‐MoC1−x by mounting zinc atoms into its lattice structure. Such a structural construction could suppress the phase transformation from α‐MoC1−x to β‐Mo2C through restricting the displacement of Mo atoms upon increased temperature. The resultant metastable α‐MoC1−x can be stabilized up to 1000 °C and this stability temperature is the highest for the metastable α‐MoC1−x so far. Synchrotron X‐ray absorption spectroscopy (XAS) and X‐ray photoelectron spectroscopy (XPS) confirm the structure of Zn‐mounted α‐MoC1−x. Density functional theory (DFT) calculations reveal that the introduction of the Zn atoms in the lattice structure of α‐MoC1−x could significantly decrease the energy difference (ΔE) between α‐MoC1−x and β‐Mo2C, thus effectively suppressing the phase transformation from α‐MoC1−x to β‐Mo2C and accordingly maintaining the high‐temperature stability of α‐MoC1−x. This novel strategy can be used as a universal method to be extended to synthesize metastable α‐MoC1−x from different precursors or other mounted elements. Moreover, the optimal product exhibits excellent lithium storage performances in terms of the cycling stability and rate performance.
Bimetallic Metal‐Organic Framework‐Derived Nanosheet‐Assembled Nanoflower Electrocatalysts for Efficient Oxygen Evolution Reaction
Authors: Li Yuwen , Lu Mengting , He Panpan , Wu Yuhang , Wang Jiawen , Chen Danni , Xu Hui , Gao Junkuo , Yao Juming 
Published: March 2019

AbstractNon‐noble metal‐based metal–organic framework (MOF)‐derived electrocatalysts have recently attracted great interest in the oxygen evolution reaction (OER). Here we report a facile synthesis of nickel‐based bimetallic electrocatalysts derived from 2D nanosheet‐assembled nanoflower‐like MOFs. The optimized morphologies and large Brunauer–Emmett–Teller (BET) surface area endow FeNi@CNF with efficient OER performance, where the aligned nanosheets can expose abundant active sites and benefit electron transfer. The complex nanoflower morphologies together with the synergistic effects between two metals attributed to the OER activity of the Ni‐based bimetallic catalysts. The optimized FeNi@CNF afforded an overpotential of 356 mV at a current density of 10 mA cm−2 with a Tafel slope of 62.6 mV dec−1, and also exhibited superior durability with only slightly degradation after 24 hours of continuous operation. The results may inspire the use of complex nanosheet‐assembled nanostructures to explore highly active catalysts for various applications.
Unification of strongly magnetized neutron stars with regard to X‐ray emission from hot spots
Authors: Yoneyama T. , Hayashida K. , Nakajima H. , Matsumoto H. 
Published: March 2019

Strongly magnetized isolated neutron stars (NSs) are categorized into two families according, mainly, to their magnetic field strength. The one with a higher magnetic field of 1014–1015 Gauss is called “magnetar,” and the other is the X‐ray isolated neutron star (XINS) with 1013 Gauss. Both magnetars and XINSs show thermal emission in X‐rays, whose spectra are different. The soft X‐ray spectrum (below 10 keV) of a magnetar is reproduced with a two‐temperature blackbody (2BB), whereas that of an XINS shows only a single‐temperature blackbody (1BB), and its temperature is even lower than that of magnetars. On the basis of the magnetic field and temperature, it is often speculated that XINSs may be old and cooled magnetars. However, no other strong observational evidence has yet been reported to support the speculation. Here, we report that all the seven known XINSs show high‐temperature emission, which should have a similar origin to that of magnetars. Analyzing all the XMM‐Newton data of the XINSs with the highest statistics ever achieved, we find that their X‐ray spectra are all reproduced with a 2BB model, similar to magnetars, as opposed to the traditional 1BB model. Their emission radii and temperature ratios are also similar to those of magnetars except for two XINSs, which show significantly smaller radii than the others. The remarkable similarity in the X‐ray spectra between XINSs and magnetars suggests that the origins of their emitting regions are also the same. The lower temperature in XINSs can be explained if XINSs are older than magnetars. Therefore, this result is another observational indication that supports the standard hypothesis of classification of highly magnetized NSs. This article is based on our paper Yoneyama et al. (2019; accepted to PASJ).
Interphases in Electroactive Suspension Systems: Where Chemistry Meets Mesoscale Physics
Authors: Shukla Garima , Franco Alejandro A. 
Published: March 2019

AbstractSemi‐solid redox flow batteries (SSRFBs) consist of electrochemically active particle suspensions as electrodes and can potentially be applied to large scale energy storage. Invented just a decade ago, these batteries already face dwindling commercial value as they can be too complex to study systematically. This review illustrates the depth and width of the state of the art of knowledge that needs to be taken into account. Additionally, this work shows how SSRFBs are an embodiment of complex systems. Conventional theoretical paradigms, experimental tools, and modeling methods generally reduce the size of the problem to solve it. However, this is nearly impossible for highly complex systems with interdependent parameter relationships. This review shows how rheology plays a very significant role in impacting electrochemistry. It concluds that the fastest way to optimize SSRFBs is by obtaining as many experimentally observable parameters as possible using advanced simultaneous techniques, followed by incorporation of this multidisciplinary data into a unified theoretical framework.
Prevalence of selected birth defects by maternal nativity status, United States, 1999–2007
Authors: Kirby Russell S. , Mai Cara T. , Wingate Martha S. , Janevic Teresa , Copeland Glenn E. , Flood Timothy J. , Isenburg Jennifer , Canfield Mark A. ,   for the National Birth Defects Prevention Network
Published: March 2019

ObjectivesWe investigated differences in prevalence of major birth defects by maternal nativity within racial/ethnic groups for 27 major birth defects.MethodsData from 11 population‐based birth defects surveillance systems in the United States including almost 13 million live births (approximately a third of U.S. births) during 1999–2007 were pooled. We calculated prevalence estimates for each birth defect for five racial/ethnic groups. Using Poisson regression, crude and adjusted prevalence ratios (aPRs) were also calculated using births to US‐born mothers as the referent group in each racial/ethnic group.ResultsApproximately 20% of case mothers and 26% of all mothers were foreign‐born. Elevated aPRs for infants with foreign‐born mothers were found for spina bifida and trisomy 13, 18, and 21, while lower prevalence patterns were found for pyloric stenosis, gastroschisis, and hypospadias.ConclusionsThis study demonstrates that birth defects prevalence varies by nativity within race/ethnic groups, with elevated prevalence ratios for some specific conditions and lower prevalence for others. More detailed analyses focusing on a broader range of maternal behaviors and characteristics are required to fully understand the implications of our findings.
Nucleotide Excision Repair and Transcription‐Associated Genome Instability
Authors: Apostolou Zivkos , Chatzinikolaou Georgia , Stratigi Kalliopi , Garinis George A. 
Published: March 2019

Transcription is a potential threat to genome integrity, and transcription‐associated DNA damage must be repaired for proper messenger RNA (mRNA) synthesis and for cells to transmit their genome intact into progeny. For a wide range of structurally diverse DNA lesions, cells employ the highly conserved nucleotide excision repair (NER) pathway to restore their genome back to its native form. Recent evidence suggests that NER factors function, in addition to the canonical DNA repair mechanism, in processes that facilitate mRNA synthesis or shape the 3D chromatin architecture. Here, these findings are critically discussed and a working model that explains the puzzling clinical heterogeneity of NER syndromes highlighting the relevance of physiological, transcription‐associated DNA damage to mammalian development and disease is proposed.
Chronic pain after hand-assisted laparoscopic donor nephrectomy
Authors: Zorgdrager M , van Londen M , Westenberg L B , Nieuwenhuijs-Moeke G J , Lange J F M , de Borst M H , Bakker S J L , Leuvenink H G D , Pol R A 
Published: March 2019

Abstract

Background
Data on chronic pain after kidney donation are sparse. The aim of this study was to assess the incidence of chronic pain after hand-assisted laparoscopic nephrectomy.

Methods
Living kidney donors who donated between 2011 and 2017 at the University Medical Centre Groningen were included. All patients underwent hand-assisted laparoscopic donor nephrectomy. Postdonation pain and movement disabilities were assessed using the Carolinas Comfort Scale (CCS) and a visual analogue scale (VAS). The prevalence, severity of pain and the need for analgesics were reported.

Results
Some 333 living kidney donors with a mean age of 56 years were included. At a median of 19 (i.q.r. 10–33) months after donation, 82 donors (24·6 per cent) had a CCS score above 0, of which 58 (71 per cent) had a CCS score of at least 2 and 57 (70 per cent) reported movement limitations. Some 110 donors (33·0 per cent) had a VAS score of more than 0. Complaints mainly occurred during bending over (12·3 per cent) and exercising (12·4 per cent). Thirty-two donors (9·7 per cent) required analgesics during follow-up between donation and the time of measurement, and six of 82 (7 per cent) reported chronic inguinal pain. In multivariable analysis, donor age (odds ratio (OR) 0·97, 95 per cent c.i. 0·95 to 0·99; P = 0·020) and length of hospital stay (OR 1·21, 1·01 to 1·51; P = 0·041) were independently associated with chronic pain.

Conclusion
One-quarter of donors experienced chronic postdonation pain or discomfort, most of which was bothersome. Younger donors and those with a longer postoperative hospital stay had more symptoms.
Bacterial cellobiose metabolism: An inquiry‐driven, comprehensive undergraduate laboratory teaching approach to promote investigative learning
Authors: Periyannan Gopal R. 
Published: March 2019

AbstractTechnique‐centered biochemistry or molecular biology undergraduate laboratory curricula do not offer significant opportunities for thoughtful, in‐depth exploration of the science to foster investigative learning. To demonstrate inclusion of inquiry‐driven laboratory experiments into the undergraduate biochemistry and molecular biology curricula, a comprehensive set of laboratory experiments, covering several principles of biochemistry and molecular biology, have been developed under a single theme. The laboratory curriculum described here comprehensively investigates bacterial cellobiose metabolism using multiple biochemical, molecular biological (RNA isolation, RT‐PCR, PCR, and enzyme assay), and analytical techniques (High Performance Liquid Chromatography, NMR, spectrophotometry, and thin‐layer chromatography) to explore the principles of metabolomics and genomics in a single undergraduate laboratory course setting using Caulobacter crescentus as the model organism. This laboratory module serves as a model for educators to develop easy‐to‐implement laboratory curricula incorporating contemporary biochemistry and molecular biology concepts and techniques to provide a course‐based undergraduate research experiences (CUREs) with defined learning objectives. © 2019 International Union of Biochemistry and Molecular Biology, 47(4):438–445, 2019.
Intracerebral transplantation of erythropoietin‐producing fibroblasts facilitates neurogenesis and functional recovery in an ischemic stroke model
Authors: Chou Pin‐Chun , Tsai Yi‐Chieh , Chen Shiu‐Jau , Tsai Li‐Kai , Chien Chung‐Liang 
Published: March 2019

AbstractIntroductionErythropoietin (EPO) can enhance neurogenesis and fibroblasts can secrete growth factors; together, they may benefit ischemic stroke. We transplanted EPO‐producing fibroblasts into the rodent infarcted brain to test their effect on neurogenesis and functional recovery.MethodsA total of 106 cells of EPO‐producing NIH/3T3 fibroblasts (EPO/EGFP/3T3) or enhanced green fluorescence protein (EGFP)‐expressing fibroblasts (EGFP/3T3) were stereotaxically injected into the infarcted striatum of adult rats that received transient middle cerebral artery occlusion (MCAO) surgery 1 day poststroke. On day 14 after MCAO, the animals were euthanized for the evaluation of neurogenesis via immunohistochemistry and of the expression of growth factors using enzyme‐linked immunosorbent assay. The infarct volume was analyzed using magnetic resonance imaging and the neurological behavior was assessed using the neurological severity scoring performed within 14 days after MCAO.ResultsThe MCAO rats with EPO/EGFP/3T3 treatment showed high EPO expression in the infarcted brain for at least 1 week. The concentration of brain‐derived neurotrophic factor was higher in both hemispheres of MCAO rats with either EGFP/3T3 or EPO/EGFP/3T3 treatment at 14 days poststroke compared with untreated MCAO rats. The number of Ki‐67‐, nestin‐, or doublecortin‐immunoreactive cells in bilateral subventricular zones was higher in EPO/EGFP/3T3‐treated MCAO rats than it was in untreated MCAO control animals, indicating the enhancement of neurogenesis after EPO/EGFP/3T3 treatment. Notably, post‐MCAO EPO/EGFP/3T3 treatment significantly reduced infarct size and improved functional recovery.ConclusionThe intracerebral transplantation of EPO‐producing fibroblasts benefited an ischemic stroke model probably via the enhancement of neurogenesis.