bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of intraoperative positioning on postoperative neurological status in cats after perineal urethrostomy
Authors: Slunsky Pavel , Brunnberg Mathias , Loderstedt Shenja , Haake Alexander , Brunnberg Leo 
Published: November 2018

Objectives The aim of this study was to evaluate and quantify the changes in neurological status in cats after perineal urethrostomy performed in dorsal and ventral recumbency. Methods This was a prospective, randomised study. Twenty male castrated cats with feline lower urinary tract disease presented for perineal urethrostomy were enrolled in this study. Surgery was performed in either dorsal recumbency (group A) or ventral recumbency (group B). Motor response of patellar tendon, gastrocnemius muscle, pelvic limb withdrawal and perineal reflexes, as well as the presence of spinal pain in the lumbosacral region, motor function of the tail and faecal continence, were examined before surgery, and 24 h and 14 days after surgery. Results The animals had a mean weight of 5.07 ± 1.08 kg, with a mean age of 6.12 ± 1.85 years. Weight and age were not significantly different between groups A and B (both P = 0.897). All tested parameters of the neurological examination performed prior to surgery were considered normal in both groups ( P = 1). The comparison between neurological examinations (perineal reflex and spinal pain) before and 24 h after surgery revealed a significantly decreased briskness of the perineal reflex and an increased occurrence of spinal pain 24 h after surgery ( P = 0.043 and P = 0.031, respectively). However, the changes of aforementioned parameters were statistically insignificant ( P = 0.249 and P = 0.141) between groups A and B. The other parameters (patellar tendon, pelvic limb withdrawal and gastrocnemius muscle reflexes, motor function of the tail and faecal continence) were statistically insignificant ( P = 1) before surgery and 24 h after surgery, as well as between groups A and B 24 h after surgery. Results of all tested parameters were statistically insignificant ( P = 1) before surgery and 14 days after surgery, as well as between groups A and B 14 days after surgery. Conclusions and relevance The briskness of the perineal reflex was significantly decreased and the occurrence of spinal pain significantly increased 24 h after surgery. A parallel with a low-grade positioning-dependent nerve injury as described in human medicine may be drawn. However, no positioning method was proven to be superior to the other.
Tentatives D'introduction Des Légumes Saumurés dans Deux Plats Sénégalais: Le “Tiébou Dienn” ou riz au poisson et le “Mafé Kandia” ou Mafé au Gombo
Authors: Adambounou T. L. , Castaigne F. , Dillon J. C. 
Published: November 2018

The cost of brined vegetables was compared with that of fresh vegetables on the basis of data collected in large vegetable markets in Senegal. The cost of vegetables brined during the period of abundance was markedly lower than that of fresh vegetables during the period when vegetables were scarce. Introducing such a method in rural Senegal would permit control of price fluctuations, which are subject to the law of supply and demand and to speculation by intermediaries in the Senegalese system of vegetable marketing. Different ways of using four brined tropical vegetables - tomatoes, eggplant, pepper, and okra - in two Senegalese dishes were studied. Mixing minced brined vegetables with untreated vegetables seems an excellent way to introduce way to introduce brined foods into dietary habits. Mafé kandia prepared from vegetables treated with 26.6 percent NaCI brine was significantly more acceptable than the same dish from vegetables treated with 20 per cent brine (P < 2.5); there was no significant difference in salty flavour between the two dishes Organoleptic tests on tiébou dienn, in which vegetables are used in large pieces that can be tasted separately, showed that the salty flavour of the tomatoes was more marked than that of the eggplant, pepper, and okra; the difference in salty flavour was significant (P = 0.5) between tomatoes and eggplant, tomatoes and okra, and pepperf and okra but not between tomatoes and pepper, pepper and eggplant, or eggplant and okra
The Role of Women in Income Production and Intra-household Allocation of Resources as a Determinant of Child Nutrition and Health
Authors: Bennett Lynn 
Published: November 2018

This article presents a theoretical framework for answering the question, Does women's income-producing work result in an improvement or a deterioration in the health and nutritional status of their children? The author maintains that the literature has not provided clear evidence that the children of working mothers have lower nutritional status than those of mothers who do not work outside the home. She notes that previous studies have not controlled either for the family's income level or for other important variables, such as the presence of an employed male and land tenure status. Bennett argues that one of the key steps in understanding women's role in the determination of child health and nutritional status “may be a careful investigation of the process of resource allocation within the household. “ She opposes the use of a single joint-utility function as an adequate representation of household decision-making dynamics. Her recommendations include conducting investigations from an interdisciplinary approach, including economics, health, nutrition, and anthropology, and she presents a framework for these investigations.
Coping Strategies of Destitute Women in Bangladesh
Authors: Katona-Apte Judit 
Published: November 2018

This article provides a description of the survival strategies of very poor women in Bangladesh, including networking, buying and selling goods, preparing foods for sale, bartering, selling their own and their children's labour, fishing and gathering food and fuel, and money lending. Katona-Apte stresses that programmes can build on successful coping strategies and provides examples of how this might work, including extending women credit for income-generating schemes. Like Rogers and Youssef, she mentions the experience of the Grameen Bank in lending to poor women to demonstrate that they are good credit risks. The article outlines the cultural and economic reasons why so many women are destitute in Bangladesh. It also describes the disproportionate and oppressive social burden they carry in their patriarchal society.
Palm Oil Use and Compatibility in India
Authors: Narasinga Rao Bagepalli S. 
Published: November 2018

India is experiencing a shortage of edible oils that may increase in years to come. To meet this challenge, palm oil is being considered as a potential new source of oil owing to the high productivity of the oil palm. Besides importing palm oil for the present, indigenous production by cultivating the oil palm has been initiated as a long-term measure. When a new edible oil is introduced, people have to be assured of its safety and nutritional quality. Besides ensuring that palm oil meets essential fatty acid (EFA) requirements, concern about its atherogenic potential due to its saturated fat content has to be allayed. The habitual low-fat Indian diet based on cereals and pulses contains invisible fats amounting to 25 g per day, but it provides two-thirds of EFA requirements. Increased consumption of fat in the form of palm oil should therefore not pose a problem to the requirements since the oil contains about 10% of n-6, 18:2 linoleic acid. Although categorized as a saturated fat, palm oil does not raise blood cholesterol, unlike other fats such as coconut oil. Unrefined crude palm oil, which is rich in β-carotene, is also of special interest as it can be used to prevent vitamin A deficiency, which is widespread In India. Owing to its technical characteristics, palm oil can be used in domestic cooking as well as in the foodprocessing industry for the manufacture of vanaspati and margarine, and as a specialty fat in the bakery and confectionery industries.
Does Posterior Scoliosis Correction Improve Respiratory Function in Adolescent Idiopathic Scoliosis? A Systematic Review and Meta-analysis
Authors: Kato So , Murray Jean-Christophe , Ganau Mario , Tan Yongyao , Oshima Yasushi , Tanaka Sakae 
Published: November 2018

Study Design: A systematic review and meta-analysis. Objectives: Pulmonary dysfunction is often advocated among the indications for surgical correction of adolescent idiopathic scoliosis (AIS). Previous studies have discussed the effect of scoliosis correction on respiratory function without reaching a definitive conclusion: Some showed that the respiratory function can improve after scoliosis surgery without defining the precise role of anterior, posterior, and combined approaches on this improvement; furthermore, the majority of these studies did not take normal growth into account. As a result, the role of surgery remains to be clarified. The object of the present study was to synthesize the current knowledge regarding changes in respiratory function after posterior corrective surgery for AIS. Methods: A comprehensive systematic search was performed to identify all relevant studies in the following electronic databases: MEDLINE, EMBASE, CINAHL (EBSCO). We focused on the studies (1) that discussed posterior fusion surgery for AIS without thoracoplasty, (2) that discussed comparisons of pre- and postoperative percent-predicted values of forced vital capacity (%FVC) or forced expiratory volume (%FEV), and (3) with minimum 2-year follow-up. Forest plots were depicted and Z value was calculated as a test for overall effect. Results: Ten studies (6 prospective and 4 retrospective studies) met our inclusion criteria. The overall effect showed that there was no significant difference in %FVC or %FEV between pre- and postoperative measurements (very low evidence). Conclusions: Posterior correction surgery for mild to moderate AIS patients showed no significant improvement of postoperative respiratory function measured by relative, percent-predicted values at minimum 2-year follow-up.
Endoscopic Brow Lift Fixation With Mitek Suture Anchors: A 9-Year Experience of a New “Ideal” Technique
Authors: Adetayo Oluwaseun A. , Wong Wendy W. , Motakef Saba , Frew Tyler G. , Campwala Insiyah , Gupta Subhas C. 
Published: November 2018

Purpose: In recent years, the endoscopic technique has emerged as a minimally invasive approach to forehead rejuvenation, although the specific need for and mode of brow fixation for endoscopic brow lifts remain under considerable debate. An ideal fixation device should provide non-palpable long-lasting fixation and allow retention of the device post-operatively without the need for removal. It should also allow precise intraoperative adjustment for symmetry and correction of brow ptosis. Methods: The authors describe an endoscopic brow lift technique using an absorbable bone anchor, Mitek Microfix. A retrospective chart review was conducted in patients who underwent endoscopic brow lift procedures utilizing this fixation method at an academic practice. Outcomes evaluated included operative times, reoperation rates, palpability, fixation device permanence, incremental costs comparisons to conventional methods, efficacy, and technical learning curve. Complication rates were evaluated and the economic, incremental cost analysis of current fixation methods was reviewed. Results: Eighty-two patients underwent single-procedure endoscopic brow fixation using the Mitek anchor over a 9-year period (2005-2014). The mean operative time was 100 minutes. There were no cases of implant palpability, alopecia, or other postoperative complications. Two patients underwent revision secondary lifts after an average of 5.5 months for temporal ptosis. Conclusion: The Mitek Microfix QuickAnchor provides durable, long-lasting fixation without device palpability. Its technical ease of use is demonstrated by the reasonable mean operative time achieved with the active involvement of resident surgeons. This device is operator-friendly, easy to use, fully indwelling, and provides lasting fixation without the development of palpability or alopecia.
10-Year Epidemiology of Ankle Injuries in Men’s and Women’s Collegiate Basketball
Authors: Tummala Sailesh V. , Hartigan David E. , Makovicka Justin L. , Patel Karan A. , Chhabra Anikar 
Published: November 2018

Background: Ankle injury is the most common injury in men’s and women’s basketball, regardless of the level of competition. Purpose: To use the National Collegiate Athletic Association (NCAA) Injury Surveillance Program/System (ISP/ISS) to review the 10-year epidemiology of ankle injuries in men’s and women’s collegiate basketball players. Study Design: Descriptive epidemiology study. Methods: The NCAA ISP was queried for men’s and women’s collegiate basketball ankle injury data from the 2004 through 2014 academic years. Ankle injury rates were calculated based on injuries per athlete-exposure (AE). Injury proportion ratios (IPRs) were determined by comparing variables between sexes. Activity and position of injury were also studied. Results: Over the 10-year study period, most ankle injuries in collegiate basketball occurred in the preseason (female, 1.45/1000 AEs; male, 2.00/1000 AEs), were contact related (female, 50.4%; male, 57.6%), were treated conservatively (female, 98.5%; male, 99.3%), and were new injuries (female, 78.0%; male, 78.9%), resulting in a time loss of less than 7 days (female, 62.7%; male, 65.2%). The most common injury types were lateral ligament complex tears (female, 83.5%; male, 80.0%), deltoid ligament tears (female, 5.6%; male, 7.2%), and high ankle sprains (female, 7.1%; male, 7.0%). Guards experienced the highest rate of ankle injuries in competition (female, 50.1%; male, 43.3%), and rebounding was found to be the most common activity during an injury (female, 30.3%; male, 34.4%). The rate of ankle injuries was significantly lower in women than in men (IPR, 0.81 [95% CI, 0.75-0.88]). Conclusion: This study found that most ankle injuries in collegiate basketball occurred during the preseason, were contact related, were treated conservatively, and were new injuries that resulted in a time loss of less than 7 days.
Recombinant factor VIII Fc fusion protein drives regulatory macrophage polarization
Authors: Kis-Toth Katalin , Rajani Gaurav Manohar , Simpson Allison , Henry Kate L. , Dumont Jennifer , Peters Robert T. , Salas Joe , Loh Christine 
Published: November 2018

AbstractThe main complication of replacement therapy with factor in hemophilia A (HemA) is the formation of inhibitors (neutralizing anti–factor VIII [FVIII] antibodies) in ∼30% of severe HemA patients. Because these inhibitors render replacement FVIII treatment essentially ineffective, preventing or eliminating them is of top priority in disease management. The extended half-life recombinant FVIII Fc fusion protein (rFVIIIFc) is an approved therapy for HemA patients. In addition, it has been reported that rFVIIIFc may induce tolerance to FVIII more readily than FVIII alone in HemA patients that have developed inhibitors. Given that the immunoglobulin G1 Fc region has the potential to interact with immune cells expressing Fc receptors (FcRs) and thereby affect the immune response to rFVIII, we investigated how human macrophages, expressing both FcRs and receptors reported to bind FVIII, respond to rFVIIIFc. We show herein that rFVIIIFc, but not rFVIII, uniquely skews macrophages toward an alternatively activated regulatory phenotype. rFVIIIFc initiates signaling events that result in morphological changes, as well as a specific gene expression and metabolic profile that is characteristic of the regulatory type Mox/M2-like macrophages. Further, these changes are dependent on rFVIIIFc-FcR interactions. Our findings elucidate mechanisms of potential immunomodulatory properties of rFVIIIFc.
30-day mortality after the start of systemic anticancer therapy for lung cancer: is it really a useful performance indicator?
Authors: Burgers Jacobus Adrianus , Damhuis Ronald Alphons 
Published: November 2018

Systemic treatment is the standard treatment for unresectable stage III and IV lung cancer. Nevertheless, a 5–10% death rate has been described within 30 days after the last systemic treatment, suggesting that these patient did not benefit. We analysed the 30-day mortality after start of systemic therapy.Data were retrieved from the Netherlands National Cancer Registry. From 2010 to 2015, 26 277 patients were included. 56% were men. The median age was 65 years and 31% of patients were aged ≥70 years. 27% involved small cell lung cancer and 73% nonsmall cell lung cancer. Overall mortality within 30 days after the start of systemic treatment was 6.2%. Multivariable analysis established the prognostic influence of age, histology, number of metastatic sites and type of systemic treatment. Chemotherapy was administered in 77 hospitals, treating each 15–161 lung cancer patients with systemic therapy annually. None of the hospitals had a significantly higher 30-day mortality according to hierarchical multivariable analysis, controlling for case-mix.In the Netherlands, the 30-day mortality rate after start of systemic therapy for lung cancer patients was comparable with earlier reports. Hospital volume did not influence the 30-day mortality rate. 30-day mortality rate is not a meaningful indicator to monitor quality of care.
Work-related variables associated with perceptions of recovery-oriented care among Quebec mental health professionals
Authors: Fleury Marie-Josée , Sabetti Judith , Grenier Guy , Bamvita Jean-Marie , Vallée Catherine , Cao Zhirong 
Published: November 2018

BackgroundProvider working conditions are important in mental health service delivery.AimsTo identify variables associated with perceived recovery-oriented care among mental health professionals.MethodA total of 315 mental health professionals and 41 managers across four Quebec service networks completed questionnaires. Univariate and multilevel mixed-effects linear regressions for bivariate and multivariate analyses were performed using independent variables from the input–mediator–output–input model and recovery-oriented care.ResultsRecovery-oriented care related to: working in primary care or out-patient mental health services, team support, team interdependence, prevalence of individuals with suicide ideation, knowledge-sharing, team reflexivity, trust, vision (a subset of team climate), belief in multidisciplinary collaboration and frequency of interaction with other organisations.ConclusionsOptimising team processes (for example knowledge-sharing) and emergent states (for example trust) may enhance recovery-oriented care. Adequate financial and other resources, stable team composition, training on recovery best practices and use of standardised assessment tools should be promoted, while strengthening primary care and interactions with other organisations.Declaration of interestNone.
Autoimmune Thyroid Disease in Islet Transplant Recipients Discontinuing Immunosuppression Late After Lymphodepletion
Authors: Dunn Alanna , Lam Anna , Hidalgo Luis , Shapiro A M James , Senior Peter A 
Published: November 2018

AbstractContextClinical islet transplantation (CIT) is an innovative strategy to treat highly selected individuals with type 1 diabetes mellitus (T1DM). Lymphodepletion with alemtuzumab or thymoglobulin is often used for induction therapy in CIT. Alemtuzumab was recently licensed as a treatment of relapsing remitting multiple sclerosis (RRMS). In RRMS, autoimmune thyroid disease (AITD) has developed in up to 40% of individuals treated with alemtuzumab. The appearance of AITD after CIT is not well described. We herein explore factors associated with AITD developing after CIT and any relationship with exposure to lymphodepleting antibodies (alemtuzumab or thymoglobulin).Case DescriptionFive cases of AITD developing after CIT for T1DM are described. All were female. Four cases had received alemtuzumab (20 to 40 mg) prior to at least one islet infusion, and one received thymoglobulin induction. The presentation with AITD was 18 to 135 months after first transplant and 11 to 18 months after withdrawal of all maintenance immunosuppression (IS). Four cases presented with clinical and biochemical evidence of hyperthyroidism from Graves disease. One case presented with biochemical evidence of hypothyroidism and positive TSH receptor antibodies. All were treated with conventional therapies for AITD.ConclusionsDespite routine use of alemtuzumab, clinical presentations of AITD seem to be uncommon in patients with CIT receiving IS. However, AITD can develop after withdrawal of IS, highlighting the need for careful thyroid surveillance in this population.
Naming and Claiming
Authors: Pyle Kai 
Published: November 2018

AbstractThis article analyzes archival and oral records of Ojibwe and Plains Cree words for Two-Spirit people to show the continuity between historical and modern Two-Spirits. In the face of appropriation of historical Two-Spirits by both cisgender and transgender non-Indigenous people, as well as scholarly insistence on a disconnect between historical and modern Two-Spirits, examining the linguistic history of specific communities reveals what the author, a Two-Spirit person themself, terms “trans*temporal kinship.” Referring to the ability of Two-Spirit people to establish kin relations across time, with both ancestors and descendants, the application of trans*temporal kinship and other Indigenous concepts allows Two-Spirit people to circumvent the debate in transgender studies as to whether transgender people can and should claim historical figures as “transgender ancestors.” The article argues that Two-Spirit reclamation of language for people “like us” is a vital element in redressing the violence and exclusion perpetrated against Two-Spirit people today.
Interview with Maya Mikdashi and Carlos Motta on Deseos /
رغبات
Authors: DeVun Leah , Tortorici Zeb 
Published: November 2018

Abstract
Special issue editors Leah DeVun and Zeb Tortorici interview Maya Mikdashi and Carlos Motta about their collaborative film, Deseos /رغبات (Desires, 2015), which places queer and gender-variant historical characters within a fluid chronological framework. In this interview, Mikdashi and Motta discuss issues such as imperial and colonial temporality, queer networks of community, and a desire for happy endings in history.
Sex Time Machine for Touching the Transcestors
Authors: Carter Julian B. 
Published: November 2018

Abstract
“Sex Time Machine for Touching the Transcestors” documents three months of Julian B. Carter’s Transgenderational Touch Project (2016–present). Carter is creating and documenting intimate contact across trans generations, mobilizing his social network to connect people old enough to be his parents with people young enough to be his children. He serves as a vector for transmitting the embodied knowledge of older generations into the lived experience of younger ones—and vice versa. The zine was originally written and illustrated as a gallery take-away for visitors to curator E. G. Crichton’s exhibit Out/Look and the Birth of the Queer at the GLBT History Museum in San Francisco, which ran from September 2017 to January 2018.
p62/SQSTM1 – steering the cell through health and disease
Authors: Sánchez-Martín Pablo , Komatsu Masaaki 
Published: November 2018

ABSTRACT
SQSTM1 (also known as p62) is a multifunctional stress-inducible scaffold protein involved in diverse cellular processes. Its functions are tightly regulated through an extensive pattern of post-translational modifications, and include the isolation of cargos degraded by autophagy, induction of the antioxidant response by the Keap1–Nrf2 system, as well as the regulation of endosomal trafficking, apoptosis and inflammation. Accordingly, malfunction of SQSTM1 is associated with a wide range of diseases, including bone and muscle disorders, neurodegenerative and metabolic diseases, and multiple forms of cancer. In this Review, we summarize current knowledge regarding regulation, post-translational modifications and functions of SQSTM1, as well as how they are dysregulated in various pathogenic contexts.