bluuebunny/crossref_metadata_2025_split huggingface dataset:
HSC70 regulates cold-induced caspase-1 hyperactivation by an autoinflammation-causing mutant of cytoplasmic immune receptor NLRC4
Authors: Raghawan Akhouri Kishore , Ramaswamy Rajashree , Radha Vegesna , Swarup Ghanshyam 
Published: October 2019

Significance
Immune receptor NLRC4 mediates caspase-1 activation upon stimulation. Mutations of NLRC4 and other cytoplasmic immune receptors cause familial cold autoinflammatory syndrome (FCAS). Individuals carrying the NLRC4-H443P mutation show exacerbated inflammation upon exposure to a cold environment due to caspase-1 hyperactivation. The mechanism of cold-induced hyperactivation of caspase-1 by none of the FCAS-causing mutants is known. We identified heat shock cognate protein 70 (HSC70) as an interacting partner of NLRC4-H443P that negatively regulates caspase-1 activation. Exposure to subnormal temperature reduces interaction of H443P with HSC70, causing caspase-1 hyperactivation. We provide a molecular mechanism for exacerbation of inflammation induced by cold temperature in individuals carrying the NLRC4-H443P mutation, which might have broader implications for temperature regulation of FCAS-causing mutations of other receptors.
Battery-free, lightweight, injectable microsystem for in vivo wireless pharmacology and optogenetics
Authors: Zhang Yi , Castro Daniel C. , Han Yuan , Wu Yixin , Guo Hexia , Weng Zhengyan , Xue Yeguang , Ausra Jokubas , Wang Xueju , Li Rui , Wu Guangfu , Vázquez-Guardado Abraham , Xie Yiwen , Xie Zhaoqian , Ostojich Diana , Peng Dongsheng , Sun Rujie , Wang Binbin , Yu Yongjoon , Leshock John P. , Qu Subing , Su Chun-Ju , Shen Wen , Hang Tao , Banks Anthony , Huang Yonggang , Radulovic Jelena , Gutruf Philipp , Bruchas Michael R. , Rogers John A. 
Published: October 2019

Significance
Neuroscience studies using optogenetics have greatly improved our understanding of brain circuits. Advances in the combined use of optogenetics and pharmacology to further probe important neurochemical signals has lagged, however, in large part due to the inconvenience of conventional cannulated approaches, as well as the difficulty in controlling, powering, and manufacturing optofluidic devices that are reliable and scalable for distribution to the neuroscience community. Here, we present a battery-free, wireless, lightweight optofluidic device that allows adjustable infusion rates, hands-free operation, and unlimited power supply, and is compatible with existing near-field communication (NFC) technology. We show that this device not only reproduces optogenetic and pharmacological experiments in vivo but, additionally, allows far greater freedom of movement in small animal models compared to existing, comparable platforms.
Directional coupling of slow and fast hippocampal gamma with neocortical alpha/beta oscillations in human episodic memory
Authors: Griffiths Benjamin J. , Parish George , Roux Frederic , Michelmann Sebastian , van der Plas Mircea , Kolibius Luca D. , Chelvarajah Ramesh , Rollings David T. , Sawlani Vijay , Hamer Hajo , Gollwitzer Stephanie , Kreiselmeyer Gernot , Staresina Bernhard , Wimber Maria , Hanslmayr Simon 
Published: October 2019

SignificanceEpisodic memories detail our personally experienced past. The formation and retrieval of these memories have long been thought to be supported by a division of labor between the neocortex and the hippocampus, where the former processes event-related information and the latter binds this information together. However, it remains unclear how the 2 regions interact. We uncover directional coupling between these regions, with power decreases in the neocortex that precede and predict power increases in the hippocampus during memory formation. Fascinatingly, this process reverses during memory retrieval, with hippocampal power increases preceding and predicting neocortical power decreases. These results suggest a bidirectional flow of information between the neocortex and hippocampus is fundamental to the formation and retrieval of episodic memories.
Conjugate hemispheric response of earth’s ionosphere due to geomagnetic storms occurred during two equinox periods
Authors: Patari Arup , De Barin Kumar , Guha Anirban , Paul Bapan 
Published: October 2019

Abstract
The ionospheric response of two geomagnetic storms of 2016 occurred during spring equinox (5-8 March, 2016) and autumn equinox (12-15 October, 2016) is investigated using the total electron content (TEC) data derived from Global Positioning System (GPS) receivers located in the equatorial ionization anomaly (EIA) crest regions at northern hemisphere (Tripura University, Agartala, India) and southern hemisphere (Karratha, Australia). While in southern EIA station ionospheric responses for the two storms are found to be symmetric but in northern EIA station the responses are completely asymmetric. The observations are explained by the contribution of storm-time prompt penetration electric fields (PPEFs), disturb dynamo electric fields (DDEFs), disturbed meridional (equatorward) winds as well as the neutral compositional changes over low latitudes.
Response of the Earth’s equatorial ionosphere during the severe G4-class geomagnetic storm of 8th September 2017
Authors: Paul Bapan , Patari Arup , De Barin Kumar , Guha Anirban 
Published: October 2019

Abstract
Equatorial and low latitude ionospheric response of the 8th September 2017 severe G4-class geomagnetic storm is investigated using the total electron content (TEC) data from a longitudinal chain of global positioning system (GPS) receivers over Asian, African and American sectors. During the main phase, a positive storm effect is observed over Asian sector, a complete negative storm effect over African sector and both are observed over American sector. A sharp increase in peak TEC is observed over the complete longitudinal chain during the recovery phase. The results show the decisive contribution of prompt penetration electric fields (PPEFs) and disturbance dynamo electric fields (DDEFs), storm time disturbed meridional (equatorward) wind as well as the neutral compositional changes over equatorial and low latitudes in the observed ionospheric storm effects.
Nature friendly cleaning: the detergency of hamburger seed
Authors: Tongbram Asha , Bhattacharyya Amitabha 
Published: October 2019

Abstract
Detergents or surfactants are surface active agents, active at surfaces and interfaces. A surfactant molecule consists of two parts. One is water liking or hydrophilic and the other is water hating or hydrophobic. When added to water, they arrange themselves at the surface and reduce the surface tension. This surface tension reduction gives the wetting ability and hence the cleaning ability of any solution. On further increasing the concentration, the surface becomes saturated with molecules. Molecules added now go to the bulk of the liquid and form closed structures called micelles, where the hydrophilic parts surround the hydrophobic parts. This concentration is called critical micelle concentration. Surfactants are widely used in homes and industry for cleaning and other purposes. Commercially prepared chemical detergents are toxic and harmful to the environment, while bio-chemical detergents, obtained from plants are less toxic. We report our work on the surface activity and cleaning ability of the seeds of Mucuna gigantea, commonly known as hamburger seed. The extract of the insides of the seeds show good surface tension reduction and foaming. We have also studied the dirt dispersion and other relevant properties of the extract. Our studies show that the seeds can probably supply a good natural detergent, bio-degradable and environment friendly.
Electron life time (τ) in trap levels of Dy3+ activated calcium aluminate: Implications in TL dosimetry
Authors: Moirangthem Nara Singh , Lisham Paris Chanu , Barua Anurup Gohain , Gartia R K 
Published: October 2019

Abstract
RE3+ (Rare Earth) activated calcium aluminates (CaAl2O4) form an excellent class of phosphors for various applications. The multi-functionality of this class of phosphor is tailored by optimising the relative concentration of the trap-levels within the large band gap (Eg=7.4eV). In this paper we determine the trap-levels in Dy3+ activated nanocrystalline calcium aluminate (CaAl2O4: Dy3+) phosphor by rigorous analysis of the complex TL curves by computerised-glow-curve-deconvolution (CGCD) technique. We assume the kinetics to be the general order kinetic (1≤ b ≤ 2). Six trap levels have been identified with a lifetime ranging from 8 hours to 108 years at room temperature. The ones with τ300 = 6.46×1005 years, 1.02×1007 years and 9.02×1008 years in principle can be the candidates for TL dosimetric application.
Polydiacetylene and imidazole mixed self-standing films for colorimetric detection of various volatile organic analytes
Authors: Suklabaidya Sudip , Chakraborty S , Sarkar S , Bhattacharjee D , Hussain Syed Arshad 
Published: October 2019

Abstract
Polydiacetylens (PDAs) have attracted great attention for application in sensing field due to their unique fluorescence and colorimetric properties. Polydiacetylenes (PDAs) are important class of polymer that exists in two distinct phases namely metastable, non-fluorescent blue phase and stable, auto-fluorescent red phase under specific conditions. PDA is obtained through polymerization of diacetylene (DA) monomers, typically using UV irradiation that leads to photopolymerization of the diacetylene lipids. Herein, the diacetylene monomer 10, 12-tricosadiynoic acid (TCDA) and N-1-hexadecyl Imidazole have been used to prepare mixed films onto a filter paper surface using the self-standing technique and then polymerizes the mixed films to get blue phase by UV irradiation. The PDA and N-1-hexadecyl Imidazole mixed films in the blue phase exhibit rapid colorimetric/fluorescence response upon exposure to various volatile organic analytes. The colorimetric and fluorogenic responses of TCDA and N-1-hexadecyl Imidazole mixed films were investigated by UV-vis absorption spectroscopy, inverting fluorescence microscopy and RGB analysis. This study demonstrates that PDA and N-1-hexadecyl Imidazole mixed films can be a used for detection of various volatile organic analytes even in naked eye.
A study of asynchronous noise in indoor power line with applications to power line communication
Authors: Baishya R , Tiru B , Sarma U 
Published: October 2019

Abstract
Power line channels do not have standard models for noise simulation. As such, study and analysis of different types of noise is imperative to developing channel simulator where communication systems can be tested and optimized for maximum efficiency. This is an indispensable part in developing power line communication systems that uses the available power line as a communication channel. This paper analyzes the asynchronous impulsive noise in indoor power line channels. The experimental setup for noise acquisition is described in detail. It is found that the impulse amplitude and the impulse durations follow the t-location scale and the log-logistic distribution better than other distribution tested. Such a distribution is easier to handle in terms of random number generation using the inverse cumulative distribution method. This can be used in the random noise simulation of impulsive noise in the generation of overall power line noise for system testing and optimization.
Phenomenological study of texture zeros of fermion mass matrices in minimal extended seesaw mechanism
Authors: Kumar P , Patgiri M 
Published: October 2019

Abstract
We study the two-zero textures in

M
v

4
×
4

in minimal extended type-I seesaw (MES) mechanism with incorporating one extra gauge singlet field ‘S’.

M
v

4
×
4

has (3×3)Dirac neutrino mass matrix MD
, (3×3) right-handed Majorana mass matrix MR
and (1×3) row matrix MS
. For our study we consider 5 zeros in MD
and 4 zeros in MR
, (5+4) scheme, along with one-zero textures of MS
to arrive at the two-zero textures of

M
v

4
×
4

. We find that out of 15 allowed two-zero textures, only 9 textures can be realized under (5+4) scheme. We also find that different textures of MD
, MR
and MS
are related to each other through S3
permutation group which leads to only a few basic combinations of MD
, MR
and MS
. We present all the combinations of MD
, MR
and MS
and show their interconvertability nature due to S
3 symmetry between them.
Study of small x behaviour of unintegrated gluon distribution constraining gluon evolution in MD-BFKL equation
Authors: Phukan P , Lalung M , Sarma J K 
Published: October 2019

Abstract
In this work we have proposed a modified form of MD-BFKL nonlinear evolution equation imposing a kinematic constraint on the gluon evolution in multi-Regge kinematics. Later we have suggested an analytical solution to our KC imposed MD-BFKL equation and studied nonlinear effect of the transverse momentum dependent (TMD) gluon distribution function at small x (10−6 ≤ x ≤ 10−2). Our results have been compared to various TMDlibuPDF datasets viz. PB-NLO-HERA I+II 2018, ccfm set A0.
Ag NP enhanced photoluminescence study of Sm3+ ions in solgel silica glasses
Authors: Dehingia Nibedita , Dutta Pankaj , Kakoti Dibyajyoti , Boruah Arindam , Rajkonwar Navaneeta , Gogoi Purabi 
Published: October 2019

Abstract
Sm3+ ions singly doped and Ag NPs co-doped with Sm3+ ions for fixed concentrations of both Ag and Sm3+ ions in sol-gel silica glasses were fabricated and their spectroscopic behaviour studied. Phenomenological Judd-Ofelt (JO) theory has been utilized for the spectroscopic characterization of the studied samples. Significant enhancement in the Sm3+ ion emissions were observed with the addition of Ag NPs. The enhancement is attributed to the local surface plasmon resonance effect of the Ag NPs.
Comparative study of oscillator strengths in dye and metal doped silica glasses
Authors: Dihingia S , Bora D , Singha R , Saikia P 
Published: October 2019

Abstract
In the present study sol gel silica glasses doped with rhodamine dye (Rh6G) and transition metals like silver, copper and iron were prepared at room temperature through sol gel route. The molar concentrations of dye and metal are varied and synthesized to get a uniform dye and metal doped clusters in silica matrices. Structural characterization is performed by SEM and XRD on doped silica glasses. SEM micrographs reveal the size of particles to be 10-50μm. The amorphous structures of the glasses are confirmed by XRD. The absorption spectra are monitored and analyzed. The absorption spectra of fluorescent dye doped sol gel silica glasses are found within the limit of 400-600 nm and the absorption spectra of different metal doped glasses are in the range of 250-350nm. Oscillator strengths of dye doped and metal doped glasses are calculated and compared. Oscillator strength of rhodamine dye doped silica glasses is comparatively higher than the other doped glasses. Silver is seen to have high oscillator strength among the metal doped silica glasses.
Fungal and bacterial community dynamics in substrates during the cultivation of morels (Morchella rufobrunnea) indoors
Authors: Longley Reid , Benucci Gian Maria Niccoló , Mills Gary , Bonito Gregory 
Published: October 2019

ABSTRACT
Morel mushrooms (Morchella, Pezizales) are highly prized edible fungi. Approaches to cultivate morels indoors in pasteurized composted substrates have been successful for Morchella rufobrunnea. We used DNA amplicon sequencing of the Internal Transcribed Spacer (ITS) ribosomal DNA and 16S rRNA gene to follow bacterial and fungal communities in substrates during indoor morel cultivation. Our goal was to determine changes in microbial communities at key stages of morel cultivation, which included primordia development, fundament initiation, differentiation and maturation. Additionally, we compared microbial communities between trays that successfully fruited to those that produced conidia and primordia but aborted before ascocarp formation (non-fruiting). The prokaryotic community was dominated by Firmicutes belonging to Bacillus and Paenibacillus with a lower abundance of Flavobacteria. At earlier stages, the fungal community was dominated by Pezizomycetes including Morchella and other species, whereas, later in the cropping cycle Sordariomycetes dominated. Additionally, differences were observed between trays with successful fruiting, which were dominated by Gilmaniella; compared to trays that did not fruit, which were dominated by Cephalotrichum. Our findings inform understanding of microbial community dynamics during morel cultivation, and show that fungal genera, such as Gilmaniella, and prokaryotic genera, such as Bacillus, are abundant in substrates that support M. rufobrunnea fruiting.
Democratic Openings and Country Visibility: Media Attention and the Allocation of US Democracy Aid, 1975–2010
Authors: Scott James M , Rowling Charles M , Jones Timothy M 
Published: October 2019

AbstractLate in the twentieth century, the United States embraced democracy promotion as a foreign policy priority, a central component of which involved allocating democracy aid to governments, political parties, and nongovernmental organizations around the world to support and encourage democratization. Nonetheless, as a scarce resource, democracy assistance is allocated selectively: some states receive substantial commitments while others receive none. As previous studies have concluded, democracy aid allocations are, in part, strategic bets placed on the likelihood of progress toward and consolidation of democracy, as donors consider cues that identify situations where democracy aid is likely to be most successful. We introduce the role of media coverage as a key factor in democracy aid allocations and argue that a shift toward democracy within a potential recipient state interacts with media attention to that state to generate cues for aid allocators. To gauge the agenda-setting and cueing effects of media coverage on democracy aid allocations, we examine US democracy assistance from 1975 to 2010, weighing the impact of media attention, democratic openings, and other factors related to recipient characteristics and US political, strategic, economic, and ideational interests on democracy assistance. We conclude with a discussion of the implications of these findings.
PIRATE: A fast and scalable pangenomics toolbox for clustering diverged orthologues in bacteria
Authors: Bayliss Sion C , Thorpe Harry A , Coyle Nicola M , Sheppard Samuel K , Feil Edward J 
Published: October 2019

Abstract

Background
Cataloguing the distribution of genes within natural bacterial populations is essential for understanding evolutionary processes and the genetic basis of adaptation. Advances in whole genome sequencing technologies have led to a vast expansion in the amount of bacterial genomes deposited in public databases. There is a pressing need for software solutions which are able to cluster, catalogue and characterise genes, or other features, in increasingly large genomic datasets.

Results
Here we present a pangenomics toolbox, PIRATE (Pangenome Iterative Refinement and Threshold Evaluation), which identifies and classifies orthologous gene families in bacterial pangenomes over a wide range of sequence similarity thresholds. PIRATE builds upon recent scalable software developments to allow for the rapid interrogation of thousands of isolates. PIRATE clusters genes (or other annotated features) over a wide range of amino acid or nucleotide identity thresholds and uses the clustering information to rapidly identify paralogous gene families and putative fission/fusion events. Furthermore, PIRATE orders the pangenome using a directed graph, provides a measure of allelic variation, and estimates sequence divergence for each gene family.

Conclusions
We demonstrate that PIRATE scales linearly with both number of samples and computation resources, allowing for analysis of large genomic datasets, and compares favorably to other popular tools. PIRATE provides a robust framework for analysing bacterial pangenomes, from largely clonal to panmictic species.
How Speculative Fiction Can Teach about Gender and Power in International Politics: A Pedagogical Overview
Authors: Boaz Cynthia 
Published: October 2019

AbstractFictional universes can be treated as discrete units of analysis in which we see the operation of international relations theory. This article discusses insights gleaned from a course created at Sonoma State University called “Gender and Geopolitics in Science Fiction and Fantasy,” in which feminist theory and international relations approaches are integrated, and science fiction and fantasy texts serve as the mechanism through which to examine the key themes and questions. This article provides an overview of the pedagogy to highlight the usefulness of speculative fiction in teaching. Each of the fictional universes is treated as a separate system where gender and political dynamics manifest in ways that observers of international relations will recognize. The core texts are Battlestar Galactica, Game of Thrones, Jessica Jones, Star Trek, Misfits, and Watchmen. The major theories and approaches explored here have implications for gender studies and feminist theory, the concepts of metaphor and allegory, and game theory.
The Etest for antimicrobial susceptibility testing of Bartonella henselae
Authors: Wolfson Candice , Branley James , Gottlieb Thomas 
Published: October 2019

Abstract
The in-vitro susceptibility of 10 isolates of Bartonella henselae was assessed using the Etest. The organisms, one reference human strain and nine feline isolates, were grown on chocolate agar and the Etests read at days 5, 8 and 11. Six antibiotics, erythromycin, azithromycin, doxycycline, ciprofloxacin, rifampicin and vancomycin were evaluated. The results correlated well with published results using agar dilution. The results confirmed the high in-vitro susceptibility of B. henselae to erythromycin, azithromycin, doxycycline and rifampicin and to a lesser extent ciprofloxacin. The majority of isolates were resistant to vancomycin. Although in-vitro results of B. henselae susceptibility testing may not necessarily correlate with clinical response, the Etest may be a simpler way for laboratories to monitor for the development of resistance particularly in the setting of relapsing infection.
Do Top Managers’ Individual Characteristics Affect Accounting Manipulation in the Public Sector?
Authors: Anessi-Pessina Eugenio , Sicilia Mariafrancesca 
Published: October 2019

AbstractDrawing on upper echelons theory, the article investigates the potential impact of top managers’ background and demographic characteristics and personality traits on organizational decisions in the public sector. The top-management figure being investigated is the municipal chief financial officer (CFO) and the specific organizational decision under analysis is the extent of revenue misrepresentation during both budget formulation and execution. The empirical setting is provided by the CFOs of Italian municipalities with populations above 15,000 over a 3-year period (2012–14). Financial data are drawn from existing databases. Non-financial data are collected through an online survey. The results show that top managers’ individual characteristics and traits do influence the extent of accounting manipulation. In particular, revenue misrepresentation was found to be smaller in the presence of female managers, managers with degrees in business administration, and managers describing themselves as “conscientious”. These effects on accounting manipulation were moderated by auditors’ and opposition councilors’ oversight, managers’ experience, and the presence of local elections. The article extends upper echelons theory and its applications in several directions: from the private to the public context, from CEOs to CFOs, from managerial decisions in general to accounting choices, and from background and demographic variables to personality traits.