bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antibiotic prescribing for endodontic infections: a survey of dental students in Italy
Authors: Salvadori M. , Audino E. , Venturi G. , Garo M. L. , Salgarello S. 
Published: April 2019

AbstractAimTo determine the knowledge of final year undergraduate students attending Italian universities on the appropriate use of systemic antibiotics for endodontic infections.MethodologyFinal year dental students from twenty Italian universities completed a one‐page questionnaire on antibiotic use for the treatment of endodontic infections. Data were analysed using descriptive statistics and chi‐square tests.ResultsA total of three hundred and three students completed the questionnaire. The average duration of antibiotic prescription proposed by respondents was 5.48 ± 1.06 days. Amoxicillin with clavulanic acid was the first‐choice antibiotic (85.2%) followed by amoxicillin alone (13.5%), azithromycin (1.0%) and clarithromycin (0.3%), for patients not allergic to penicillin. Clarithromycin was the first‐choice drug for patients with a penicillin allergy (56.1%), followed from azithromycin (31.7%), clindamycin (11.9%) and levofloxacin (0.3%). Alveolar abscess with systemic manifestations was reported as the principal reason to prescribe antibiotics (97.7%) followed by the same condition without systemic manifestations (85.5%). For the scenario of irreversible pulpitis, 5% of students considered antibiotics necessary. Almost 52% of students would prescribe antibiotics for apical acute periodontitis; 29.7% would prescribe antibiotics for chronic apical periodontitis with sinus tract, and 13.5% indicated these drugs for chronic apical periodontitis without sinus tract.ConclusionsThe results demonstrate that it is necessary to improve the knowledge of Italian students on antibiotics and indications for their use in endodontics.
Influence of apical preparation size and irrigation technique on root canal debridement: a histological analysis of round and oval root canals
Authors: Lee O. Y. S. , Khan K. , Li K. Y. , Shetty H. , Abiad R. S. , Cheung G. S. P. , Neelakantan P. 
Published: April 2019

AbstractAimTo examine the debridement of round and oval root canals prepared to two apical sizes with and without ultrasonically activated irrigation.MethodologyMandibular premolars with round (n = 48) and oval (n = 48) root canals were pair‐matched after microCT scanning and randomly divided into two experimental groups (n = 20): group 1, rotary NiTi to size 20, .04 taper; group 2, rotary NiTi to size 40, .04 taper. Specimens were subdivided into two subgroups (n = 10): subgroup A, syringe and needle (SNI); subgroup B, ultrasonically activated irrigation (UAI). Untreated canals (eight oval and eight round) served as controls. Specimens were processed for histological evaluation for measurement of the remaining pulp tissue and debris (RPT), and the perimeter percentage of root canal area untouched by the instruments (PRAU). Following assessment of normality, multiple‐way anova models were used to study the effects of preparation size, irrigation technique and canal cross‐sectional shape, and their interactions on the RPT and PRAU (α = 0.05).ResultsAll experimental groups had significantly less RPT than the control (P < 0.05). Both the preparation size (20 vs. 40) and the irrigation technique (SNI vs. UAI) had a significant effect on RPT (P = 0.006 and P < 0.001, respectively). Groups irrigated with SNI always had significantly greater RPT than those irrigated with UAI, irrespective of the preparation size (P < 0.001). Canals prepared to size 20 had significantly greater RPT than those with size 40 in the SNI subgroup (P < 0.001), but there was no significant difference in the UAI subgroup (P = 0.481).ConclusionsRoot canals prepared to a larger size (40) were cleaner than those prepared to a smaller size (20), when irrigation was performed with a syringe and needle. When the irrigant was ultrasonically activated, smaller preparations resulted in canals that were as clean as larger preparations. This finding was common to both round and oval canals of freshly extracted premolars with vital pulp tissue.
THE PHILLIPS CURVE IN A MATCHING MODEL
Authors: Hu Tai‐Wei , Wallace Neil 
Published: April 2019

AbstractFollowing ideas in Hume, monetary shocks are embedded in the Lagos‐Wright model in a new way: There are only nominal shocks accomplished by individual transfers that are sufficiently noisy so that realizations of those transfers do not permit the agents to deduce much about the aggregate realization. Assuming that the distribution of aggregate shocks is almost degenerate, aggregate output increases with the growth rate of the stock of money—our definition of the Phillips curve. This almost degeneracy assumption is far from being necessary; under some mild conditions, the Phillips curve result holds for a large class of distributions.
APPARENT BIAS: WHAT DOES ATTITUDE POLARIZATION SHOW?
Authors: Benoît Jean‐Pierre , Dubra Juan 
Published: April 2019

AbstractMany, though not all, experiments have found that exposing groups of subjects who disagree to the same evidence may cause their initial attitudes to strengthen and move further apart, or polarize. Some have concluded that findings of attitude polarization show that people process information in a biased manner so as to support their initial views. We argue that, on the contrary, polarization is often what we should expect to find in an unbiased Bayesian population, in the context of experiments that find polarization.
Do Patented Innovations Reduce Stock Price Crash Risk?*
Authors: Ben‐Nasr Hamdi , Bouslimi Lobna , Zhong Rui 
Published: April 2019

AbstractUsing a large sample of US firms, we document a significantly negative relation between the number of patents (citations) and stock price crash risk. Our findings are consistent with the arguments that patented innovation activities send a high‐quality signal and reduces proprietary information costs, which lowers information asymmetry and enhance disclosure. Further, we find that such impact of patented innovation on stock price crash risk is more pronounced in firms with weak corporate governance and high information opacity. Our findings provide new evidence on the real effects of patented innovation on crash risk in equity market.
The practice of collective bargaining in the private sector in Quebec (Canada): the changing ‘rules of the game’
Authors: Hennebert Marc‐Antonin , Pérez‐Lauzon Sara 
Published: April 2019

AbstractDrawing on 45 semi‐structured interviews with union negotiators active in the Quebec private sector, this article shows that local bargaining practices, despite their plurality, have tended to change following major trends. It also reveals, more fundamentally, a redefinition of the ‘rules of the game’. The transformation and stability of these social rules, which are much more focused on the needs of employers, have tended to weaken collective bargaining as a tool for industrial democracy.
A hybrid neural network approach to minimize total completion time on a single batch processing machine
Authors: Rafiee Parsa N. , Keshavarz T. , Karimi B. , Moattar Husseini S. M. 
Published: April 2019

AbstractIn this research, the problem of scheduling a single batch processing machine (BPM) with nonidentical job sizes is considered. The objective is to minimize the total completion time of the jobs. A BPM can process a group of jobs simultaneously as a batch as long as its capacity is not violated. The processing time of a batch is equal to the maximum processing time of all the jobs in the batch. The research problem is formulated as a mixed integer linear programming model. Since the problem under study is shown to be NP‐hard, a neural network based approach that combines a heuristic algorithm and the iterative learning approach is proposed. The computational experiments are designed to compare the effectiveness of the neural network approach with CPLEX and the other available heuristics in the literature. The results show that the proposed approach outperforms the other algorithms in terms of solution quality.
Dynamic testing: Can a robot as tutor be of help in assessing children's potential for learning?
Authors: Resing Wilma C.M. , Bakker Merel , Elliott Julian G. , Vogelaar Bart 
Published: April 2019

AbstractThis study examined whether computerized dynamic testing by utilizing a robot would lead to different patterns in children's (aged 6–9 years) potential for learning and strategy use when solving series‐completion tasks. The robot, in a “Wizard of Oz” setting, provided instructions and prompts during dynamic testing. It was found that a dynamic training resulted in greater accuracy and more correctly placed pieces at the post‐test than repeated testing only. Moreover, children who were dynamically trained appeared to use more heuristic strategies at the post‐test than their peers who were not trained. In general, observations showed that children were excited to work with the robot. All in all, the study revealed that computerized dynamic testing by means of a robot has much potential in tapping into children's potential for learning and strategy use. The implications of using a robot in educational assessment were stressed further in the discussion.
Isorhamnetin attenuates osteoarthritis by inhibiting osteoclastogenesis and protecting chondrocytes through modulating reactive oxygen species homeostasis
Authors: Zhou Feng , Mei Jingtian , Yuan Kai , Han Xiuguo , Qiao Han , Tang Tingting 
Published: April 2019

AbstractIncreasing evidence indicates that osteoarthritis (OA) is a musculoskeletal disease affecting the whole joint, including both cartilage and subchondral bone. Reactive oxygen species (ROS) have been demonstrated to be one of the important destructive factors during early‐stage OA development. The objective of this study was to investigate isorhamnetin (Iso) treatment on osteoclast formation and chondrocyte protection to attenuate OA by modulating ROS. Receptor activator of nuclear factor‐kappa B ligand (RANKL) was used to establish the osteoclast differentiation model in bone marrow macrophages (BMMs) in vivo. H2O2 was used to induce ROS, which could further cause chondrocyte apoptosis. We demonstrated that Iso suppressed RANKL‐induced ROS generation, which could mediate osteoclastogenesis. Moreover, we found that Iso inhibited osteoclast formation and function by suppressing the expression of osteoclastogenesis‐related genes and proteins. We proved that Iso inhibited RANKL‐induced activation of mitogen‐activated protein kinase activation of mitogen‐activated protein kinase (MAPK), nuclear factor‐kappa B (NF‐κB) and AKT signalling pathways in BMMs. In addition, Iso inhibited ROS‐induced chondrocyte apoptosis by regulating apoptosis‐related proteins. Moreover, Iso was administered to an anterior cruciate ligament transection (ACLT)‐induced OA mouse model. The results indicated that Iso exerted beneficial effects on inhibiting excessive osteoclast activity and chondrocyte apoptosis, which further remedied cartilage damage. Overall, our data showed that Iso is an effective candidate for treating OA.
Empathy and burnout: A multicentre comparative study between residents and specialists
Authors: Ferreira Sara , Afonso Pedro , Ramos Maria do Rosário 
Published: April 2019

AbstractRationale, Aims, and ObjectivesThe prevalence of burnout among medical doctors and its negative effect on empathy can influence therapeutic success. The aim of this study was to compare the levels of empathy and burnout between residents and specialists as well as to study the correlation between empathy and burnout.MethodsThis is an exploratory study of a convenience sample of 104 doctors who work in health institutions in Greater Lisbon area in Portugal, covering central hospitals, district hospitals, and health centres. Each doctor filled in a questionnaire, which included the Maslach Burnout Inventory (MBI) and the Jefferson Scale of Empathy (JSE).ResultsParticipants were divided in two subgroups: 51% residents (n = 53) and 49% specialists (n = 51). A difference (p = .048) in JSE scores between residents (mean 116.4, SD 12.8) and specialists (mean 120.78, SD 12.84) has been identified. Furthermore, in all three MBI subscales (emotional exhaustion, depersonalization, and lack of personal accomplishment), the group of residents showed significantly higher mean scores. In general, empathy scores showed an inverse relationship between depersonalization (r = –0.390, p < .0001) and lack of personal accomplishment (r = –0.447, p < .0001). Finally, we found that an increase in MBI level is associated with a decrease in empathy levels.ConclusionOur findings suggest that there is a significant difference in burnout subscales scores between residents and specialists and that these have a negative correlation with empathy level. These exploratory results draw attention to the importance of preventing burnout in hospital and health care centres professionals, in particular in residents, through the implementation of individual and organizational structured measures.
Soft tissue replication in single unit implant impressions—A three dimensional clinical study
Authors: da Silva Marques Duarte Nuno , Marques Pinto Ricardo Jorge , Alves Rita Vanessa Aparício Aguiar , Baratieri Luiz Narciso , da Mata António Duarte Sola Pereira , Caramês João Manuel Mendez 
Published: April 2019

AbstractObjectiveComparison of soft tissue replication between conventional and digital impressions for definitive single unit implant rehabilitation in the esthetic zone.Materials and MethodsSix patients were recruited according to inclusion criteria for this cross‐over pilot study and submitted to a conventional silicone implant impression with customized coping and a digital impression with an intraoral scanner. Stereolithography files obtained from the same patient were superimposed with appropriate software and trueness evaluated between methods at predetermined locations (56 in hard and soft tissues and 18 in the emergence profile, per patient). Results were presented as mean root mean square (RMS) ± 95% confidence interval and effect size calculated with Hedges' g ± 95%. Mann‐Whitney and Kruskal‐Wallis were performed when appropriate and α was set at .05.ResultsTrueness between methods equated to 51.08[45.68;56.47] μm and 60.46[52.29;68.62] μm in hard and soft tissues, respectively. Soft tissue replication by intraoral scanner acquisition corresponded to a statistically significant RMS of 243.89[209.15;278.63] μm equating to a Hedges' g of 1.52[1.22;1.82] which corresponded to a large effect size.ConclusionsThe proposed method could be considered for soft tissues assessment and the results suggest that intraoral impression techniques produce statistically significant changes in peri‐implant soft tissue replication, although below the clinically detectable threshold.Clinical SignificanceThe proposed technique allows for the 3D determination of peri‐implant tissues changes in digital models with higher sensitivity than visual techniques, thus presenting itself as a promising alternative in clinical studies and that the use of an intraoral scanner obtained significant differences in the soft tissue emergence profile replication when compared with the gold standard.
Rumen parameters of yaks (Bos grunniens) and indigenous cattle (Bos taurus) grazing on the Qinghai‐Tibetan Plateau
Authors: Shi Fuyu , Wang Hucheng , Degen Abraham Allan , Zhou Jianwei , Guo Na , Mudassar Shah , Long Ruijun 
Published: April 2019

AbstractYaks and indigenous Qaidam cattle and cattle‐yak crosses (C × Y) graze on the Qinghai‐Tibetan Plateau (QTP) throughout the year, but yaks are raised at higher elevations than cattle. Yaks do not receive supplementary feed whereas cattle require supplementary feed during harsh winter. We hypothesized that yaks would cope with the severe conditions of the QTP better than cattle and utilize the pasture more efficiently. We also hypothesized that differences between species would be pronounced in winter, when conditions are particularly harsh. To test these hypotheses, seasonal rumen fluid parameters of yaks, C × Y and cattle (n = 3 for each) were examined. Rumen fluid was collected in summer and winter from each genotype 2, 5 and 12 hr after a day of grazing. Concentrations of total volatile fatty acid (VFA), acetate, propionate, isobutyrate and isovalerate were greater in yaks than in cattle in summer (p < 0.05), while propionate concentration was lower in yaks than in cattle in winter (p < 0.05). Concentrations of ammonia and urea were greater (p < 0.001) in yaks than in cattle (p < 0.001) in summer, whereas, concentrations of free amino acids (AA) were greater in cattle than in yaks in summer and winter (p < 0.001). Concentrations of total VFA, acetate, propionate and butyrate decreased linearly (p < 0.05), whereas concentrations of isobutyrate and isovalerate increased linearly for yak and C × Y with sampling time (p < 0.05) in summer. In summer, concentrations of isobutyrate and isovalerate were greater in yaks than in cattle (p < 0.05). In conclusion, rumen fermentation characteristics of yaks showed that they coped better than cattle or C × Y in the harsh climate as we hypothesized. However, in contrast to our hypothesis, this emerged only in summer, when pasture was plentiful and not in winter, when pasture was scarce.
Link between insomnia and perinatal depressive symptoms: A meta‐analysis
Authors: Emamian Farnoosh , Khazaie Habibolah , Okun Michele L. , Tahmasian Masoud , Sepehry Amir A. 
Published: April 2019

AbstractEvidence shows the possible link between insomnia and perinatal depressive symptoms. In order to find a convergent quantitative answer, we collected data via the search of Medline, EMBASE and reference tracking, which included nine studies (a total sample of 1,922 women). An aggregate effect size estimate (correlation coefficient) was generated using the comprehensive meta‐analysis software. For the meta‐analytic procedure, a random effects model was set a priori. Moderating factors, including study design, method of assessment of depression, geographical origin of data, publication year, mean age, % married, breastfeeding rate, quality and type of data, % primiparous and history of depression, were examined via categorical or univariate mixed‐effects (method of moments) meta‐regression methods. Heterogeneity and publication bias were examined using standard meta‐analytic approaches. We found a significant, medium‐size relationship between insomnia and perinatal depressive symptoms (point estimate, 0.366; 95% confidence interval [CI], 0.205–0.508; p < 0.001; n = 9) and this was significantly heterogeneous (Q, 118.77; df, 8; p < 0.001; I2, 93.26%). The effect size estimate was significant for studies reporting no history of depression (point estimate, 0.364; 95% CI, 0.035–0.622; p < 0.05; n = 5) and for study design. With meta‐regression, no moderating factor (age, marriage rate, breastfeeding rate, pregnancy history or publication year) significantly mediated the effect size estimate. The depression assessment scale used, but not other categorical variables, explained the magnitude of heterogeneity. We found that insomnia during the perinatal period is associated with depressive symptoms, which warrants screening pregnant mothers for insomnia and depression.
Extra‐pair mating in a socially monogamous and paternal mouth‐brooding cardinalfish
Authors: Rueger Theresa , Harrison Hugo B. , Gardiner Naomi M. , Berumen Michael L. , Jones Geoffrey P. 
Published: April 2019

AbstractMany vertebrates form monogamous pairs to mate and care for their offspring. However, genetic tools have increasingly shown that offspring often arise from matings outside of the monogamous pair bond. Social monogamy is relatively common in coral reef fishes, but there have been few studies that have confirmed monogamy or extra‐pair reproduction, either for males or for females. Here, long‐term observations and genetic tools were applied to examine the parentage of embryos in a paternally mouth‐brooding cardinalfish, Sphaeramia nematoptera. Paternal care in fishes, such as mouth‐brooding, is thought to be associated with a high degree of confidence in paternity. Two years of observations confirmed that S. nematoptera form long‐term pair bonds within larger groups. However, genetic parentage revealed extra‐pair mating by both sexes. Of 105 broods analysed from 64 males, 30.1% were mothered by a female that was not the partner and 11.5% of broods included eggs from two females. Despite the high paternal investment associated with mouth‐brooding, 7.6% of broods were fertilized by two males. Extra‐pair matings appeared to be opportunistic encounters with individuals from outside the immediate group. We argue that while pair formation contributes to group cohesion, both males and females can maximize lifetime reproductive success by taking advantage of extra‐pair mating opportunities.
Engagement in the Use of English and Chinese as Foreign Languages: The Role of Learner‐Generated Content in Instructional Task Design
Authors: LAMBERT CRAIG , ZHANG GRACE 
Published: April 2019

AbstractThis study investigates learner engagement in pedagogic task performance by triangulating multiple sources of data to gain insight into the cognitive and affective processes that take place on a range of tasks and how they engage learners of different target languages. The study provides a detailed analysis of 4 learners’ second language (L2) performance (2 first language [L1] Japanese learners of English; 2 L1 Japanese learners of Chinese). All learners completed an identical set of 12 communication tasks in 3 discourse genres (instruction, narrative, and opinion) in a learner‐generated (LGC) and teacher‐generated content (TGC) condition. The performances were followed by immediate stimulated video recalls and questionnaires on perceived levels of anxiety and motivation during each task. Triangulation of these data sources revealed that both the English and Chinese learners were more socially and emotionally engaged in LGC tasks than in TGC tasks and that this engagement was associated with more fluent and accurate, but less complex, speech. The difference between the Chinese and English learners was in their self‐reported preferences and levels of anxiety and motivation while performing the tasks in the respective conditions. Based on the learners’ background profiles, this difference in subjective response to the tasks is attributed to previous experience with formal L2 instruction.
Nexus of Christian Mysteries: The Filioque and its Doctrinal “Life-Significance”
Authors: Owens Shane M. 
Published: April 2019

AbstractNeither a recapitulation of the Catholic Church's teaching on the Filioque nor a comprehensive reconstruction of Thomas Aquinas’ theology of the Spirit, this paper is instead a response to several objections raised against Thomas’ defense of the Filioque by the highly-original Orthodox theologian Sergei Bulgakov. Following his patristic predecessors, particularly Augustine of Hippo and Cyril of Alexandria, and the conciliar tradition, Thomas situates the contemplation of the Spirit's procession within Christology—for He is the Spirit of Christ (see Rom. 8:9). The Christological framing of the Spirit's procession a Filio leavens theological examination of the doctrine's expansive influence on the understanding of other Christian Mysteries. By examining Matthias Joseph Scheeben's speculative reflections on the procession of the Spirit as analogous to the creation of Eve and illuminative of the Church as Bride of Christ, Bulgakov's most damning criticism, that the Filioque is a theologoumenon lacking in “life-significance” is rebutted. Finally, additional avenues of elaborating upon the Spirit's procession as indivisibly connected to other mysteries of the faith are advanced.