bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nurse Turnover: Implication on Health Care Delivery
Authors: Bisnar Joyce C. , Pegarro Kathleya Grace N. 
Published: February 2019

Nurse turnover is a major problem to all health care organizations because of its strong effects on client outcomes, motivation to work, job dissatisfaction and provision of quality patient care. The study aimed to determine the implication/ effects of nurse's turnover on healthcare delivery. Mixed method and Descriptive research design were employed, and the census was used in the selection of the participants. A validated self- made questionnaire, focus group discussion and key informant interview was utilized to gather the empirical data required. The study revealed that there was a decrease nurse turnover rate in the government hospital and an increase in private hospitals due to low salary, no/ less fringe benefits, poor/no health insurance coverage, better benefits and compensation package offered by other hospitals/countries and lower patient ratio. However, with the increase or decrease in the turnover rate, health care delivery in relation to the identified five (5) key areas of nurses' responsibility are still affected due to increased nurse-client ratio, interpersonal relationship, stressful environment and attitudes of the millennial nurses. Further, the majority of the participants are millennials and they outnumbered the generation X and baby boomers who created a generation gap in terms of health care delivery. This shift in attitude poses a great challenge for hospitals to retain millennials because they are growing in numbers and are replacing baby boomers and generation X. Thus, hospitals had to learn, adjust and develop management strategies to accommodate and understand the unique style and attitudes of the millennials for retention.
Sexism in English Reference Books Used by College Freshmen: Implications for Gender Equality
Authors: Muncada Luisito P. 
Published: February 2019

Sexist words in the books showed an unfair treatment of the female gender. The generic term, man, refers not only to a male person but also to denote humanity. The personal pronoun is used to refer to a hypothetical person in general and accepted in Filipino society. This research is a qualitative study that used content analysis to interpret the data. Sexism was found evident in English references. It is recommended that the sentences containing sexist language be taken out of the 12 books dissected for political correctness to make them gender fair. The textbook Board should be aware of RA 7192 (DepEd, GAD program) and CHED Memo No. 1, s. 2015, they should be gender sensitive. Policymakers should be mindful of the dynamism of language, and its importance in education must be more responsive to the needs of the time through quality language and gender sensitive. Publishers are cautioned to exact gender-fair language from their clients so that both sexes get equal treatment in publication. Students should be alerted to sexist language, and teachers should teach gender sensitivity, even only as incidental teaching. English reference books used by the college freshmen should be reviewed, and those who found out to be sexist should be substituted with gender-fair ones.
Efficacy and safety of DL‐3‐N‐butylphthalide in the treatment of ischemic poststroke aphasia: A randomized clinical trial
Authors: Tian Jing , Yang Peng , Yang Jianing , Wang Rui , Zhou Biyi , Zhang Kun , Zhao Yanying , Wang Binbin , Liu Lijuan , Chen Ruomeng , Wu Haoran , Miao Ruihan , Guo Li , Liu Xiaoyun 
Published: November 2024

AbstractObjectivePoststroke aphasia (PSA) has a high prevalence and requires a long recovery period, severely impairing life and work. Its existing behavioral interventions, principally speech and language therapy, are limited by numerous factors. The aims of this study are to evaluate the efficacy and safety of DL‐3‐N‐butylphthalein (NBP) and explore its mechanism in the treatment of ischemic PSA.MethodsPatients hospitalized in the Second Hospital of Hebei Medical University in China were randomly administered NBP soft capsules or placebo orally for 6 months from July 1, 2021, to February 25, 2023. Language skills were assessed using the Western Aphasia Battery‐Aphasia Quotient (WAB‐AQ). We collected plasma samples and detected neurotransmitters by liquid chromatography‐mass spectrometry.ResultsIn total, 118 out of 124 patients were included in the outcome analysis. Compared with the control group, AQ values in the NBP group significantly improved at 6 months (U = 1187.5, p = 0.003). After eliminating baseline interference, NBP treatment was independently associated with the 6‐month AQ improvement [mean difference (MD) 0.106, 95% confidence interval (CI) 0.018, 0.195, p = 0.019]. We observed no statistically significant difference between the groups in abnormal liver function at 1 month [relative risk (RR) 1.07, 95% CI 0.89, 1.28] and 6 months [RR 0.99, 95% CI 0.86, 1.42]. Statistically significant differences were observed in tyrosine (p = 0.043) and 5‐hydroxytryptophan (p = 0.041) between the two groups.InterpretationNBP treatment might promote the recovery of WAB‐AQ in patients with ischemic PSA by increasing levels of monoamine neurotransmitters.
Thermo‐mechanical Study on Auxetic Shape Memory Periodic Open Cellular Structures—Part II: Mechanical and Shape Memory Properties
Authors: Fink Alexander , Rudolf Dominik , Wahlmann Benjamin , Freund Hannsjörg , Körner Carolin 
Published: November 2024

This study explores the potential of periodic open cellular structures (POCS) that combine the auxetic and the shape memory effect (SME) with the aim of enhancing heat transfer in catalytic tubular reactors. On the one hand, these structures exhibit a negative Poisson's ratio, contracting perpendicular to the load axis under compression, driven by the rotation of nodes generating complex stress fields. On the other hand, the shape memory alloy (SMA) Nitinol (NiTi) with a reversible strain of up to 8% produced via electron beam powder bed fusion (PBF‐EB) shows extraordinary material properties with a high degree of freedom in structure design. The study conducts finite element method simulations and experiments to design POCS with tailored properties. Compression tests on less expensive Ti‐6Al‐4V POCS compared to NiTi POCS validate the simulative parameter study applied to fabricate novel auxetic hexagonal reentrant structures from NiTi with a unique stacking order and curved struts. The aim of this part of the study is to offer a pathway to design a NiTi auxetic POCS based on validated simulations. Further, it explains the interactions between geometrical parameters and mechanical properties of cellular reentrant NiTi structures. An optimized auxetic NiTi POCS achieved a Poisson's ratio of −1.
Precise Molecular Engineering of Multi‐Suborganelle Targeted NIR Type‑I AIE Photosensitizer and Design of Cell Membrane‐Anchored Anti‐Tumor Pyroptosis Vaccine
Authors: Xiang Chunbai , Liu Yu , Ding Qihang , Jiang Ting , Li Chao , Xiang Jingjing , Yang Xing , Yang Ting , Wang Yue , Tan Yanfei , Mei Ling , Lu Zhiyun , Kim Jong Seung , Gong Ping 
Published: November 2024

AbstractPhotodynamically induced cell immunogenic death has emerged as an effective antitumor strategy because of its capacity to stimulate anti‐tumor immunity for eliminating primary tumors and metastases. Considering that the short‐lived reactive oxygen species (ROS) and the anoxic tumor microenvironment restrict the efficacy of conventional photodynamic therapy (PDT), a molecular framework of near‐infrared (NIR) type I aggregation‐induced emission (AIE) photosensitivities with tunable sub‐organelles (including cell membranes, mitochondria, lipid drops, lysosomes, and endoplasmic reticulum) targeting type I ROS in precisely regulated subcellular locations are designed. Subsequent studies have discovered that under 660 nm laser irradiation, the cell membrane‐targeted TCF‐Mem can effectively induce pyroptosis of cancer cells, fully enhancing anti‐tumor immunity in vivo in a preventive tumor vaccine model. Additionally, in vivo anti‐tumor type I PDT can eradicate the primary tumor and, more importantly, inhibit the growth of distant tumors through in vitro actions, thereby obtaining specific anti‐tumor immunity. This study provides a novel framework for the rational design of photosensitive sub‐organelles targeting NIR type I AIE and offers a new perspective for innovative PDT‐based tumor therapy and immune enhancement strategies.
Antitumor Cream: Transdermal Hydrogel Containing Liposome‐Encapsulated Ruthenium Complex for Infrared‐Controlled Multimodal Synergistic Therapy
Authors: Yan Yu‐Fei , Li Xue‐Lian , Zeng Li‐Zhen , Liu Qishuai , Cai Zhongyan , Ren Yanrong , Ren Xiaoxia , Gao Feng 
Published: November 2024

AbstractA transdermal drug delivery cream, which is non‐invasive and painless, containing a liposome‐encapsulated Ru(II) complex (LipoRu) is created for the treatment of skin cancer. This formulation capitalizes on the synergistic antitumor effects of two‐photon excited photodynamic therapy (PDT), photothermal therapy (PTT), and chemotherapy. LipoRu exhibits effective tumor accumulation, efficient cellular uptake, pH‐sensitive and infrared‐accelerated release, and dual localization to the nucleus and mitochondria. The released Ru(II) complexes within cells exert multiple antitumor mechanisms, such as DNA topoisomerase and RNA polymerase inhibition, Type I and II PDT, PTT, DNA photodamage, and apoptosis and ferroptosis induction. The biodistribution and therapeutic efficacy of LipoRu in vivo are systematically compared via three distinct administration routes: intratumoral injection, intravenous injection, and transdermal delivery through topical cream application. The positive therapeutic effects of the LipoRu cream fabricated here in subcutaneous tumor‐bearing mice offer optimistic potential for the painless and non‐invasive treatment of both early‐stage and advanced skin cancers, as well as superficially located solid tumors.
Scalable Multistep Roll‐to‐Roll Printing of Multifunctional and Robust Reentrant Microcavity Surfaces via a Wetting‐Induced Process
Authors: Choi Su Hyun , Shin Seungwoo , Kim Woo Young , Lee Je Min , Park Seo Rim , Kim Hyuntae , Woo Kyoohee , Kwon Sin , Fang Nicholas X. , Kim Seok , Cho Young Tae 
Published: November 2024

AbstractOwing to their unique structural robustness, interconnected reentrant structures offer multifunctionality for various applications. a scalable multistep roll‐to‐roll printing method is proposed for fabricating reentrant microcavity surfaces, coined as wetting‐induced interconnected reentrant geometry (WING) process. The key to the proposed WING process is a highly reproducible reentrant structure formation controlled by the capillary action during contact between prefabricated microcavity structure and spray‐coated ultraviolet‐curable resins. It demonstrates the superior liquid repellency of the WING structures, which maintain large contact angles even with low‐surface‐tension liquids, and their robust capability to retain solid particles and liquids under external forces. In addition, the scalable and continuous fabrication approach addresses the limitations of existing methods, providing a cost‐effective and high‐throughput solution for creating multifunctional reentrant surfaces for anti‐icing, biofouling prevention, and particle capture.
Self‐Assembled Hollow Gyroids with Bicontinuous Mesostructures: A Highly Robust Electrocatalyst Fixation Platform
Authors: Lee Gun Ho , Choi Seongsu , Yang HyunWoo , Lee SangJae , Jang Hanhwi , Lee Gyu Rac , Kim Ye Ji , Cho EunAe , Jung Yeon Sik 
Published: November 2024

AbstractThe electrochemical degradation of Pt/C in commercial proton exchange membrane fuel cells (PEMFCs) is a major challenge that limits their durability and performance. This degradation mainly arises from carbon corrosion, which facilitates the detachment of electrocatalyst particles that are weakly bound to catalyst supports. Herein, unusually robust hollow gyroid morphologies designed for strong electrocatalyst fixation and extensive surface accessibility during oxygen reduction reactions (ORR) are reported. To obtain self‐assembled gyroid nanostructures using a poly(styrene‐b‐2‐vinylpyridine) (PS‐b‐P2VP) block copolymer, a solvent vapour treatment with dimethylformamide, which is highly selective for the P2VP block, is applied. It is discovered that retaining residual solvent in the gyroid‐forming P2VP microdomain before carbonization is crucial for forming hollow gyroids with embedded electrocatalysts. These hollow gyroid carbon‐Pt (HGC‐Pt) nanostructures exhibit a 3.6‐fold enhancement in electrochemically active surface area compared to solid gyroid carbon (SGC) counterparts. Based on systematic analyses, this exceptional electrochemical stability is attributed to greatly enhanced surface accessibility derived from the hollow geometry, uniform and robust catalyst embedding, and extensive pyridinic nitrogen doping from the P2VP block.
Trace Adsorptive Removal of PFAS from Water by Optimizing the UiO‐66 MOF Interface
Authors: Ilić Nebojša , Tan Kui , Mayr Felix , Hou Shujin , Aumeier Benedikt M. , Morales Eder Moisés Cedeño , Hübner Uwe , Cookman Jennifer , Schneemann Andreas , Gagliardi Alessio , Drewes Jörg E. , Fischer Roland A. , Mukherjee Soumya 
Published: November 2024

AbstractThe confluence of pervasiveness, bioaccumulation, and toxicity in freshwater contaminants presents an environmental threat second to none. Exemplifying this trifecta, per‐ and polyfluoroalkyl substances (PFAS) present an alarming hazard among the emerging contaminants. State‐of‐the‐art PFAS adsorbents used in drinking water treatment, namely, activated carbons and ion‐exchange resins, are handicapped by low adsorption capacity, competitive adsorption, and/or slow kinetics. To overcome these shortcomings, metal–organic frameworks (MOFs) with tailored pore size, surface, and pore chemistry are promising alternatives. Thanks to the compositional modularity of MOFs and polymer–MOF composites, herein we report on a series of water‐stable zirconium carboxylate MOFs and their low‐cost polymer‐grafted composites as C8–PFAS adsorbents with benchmark kinetics and “parts per billion” removal efficiencies. Bespoke insights into the structure–function relationships of PFAS adsorbents are obtained by leveraging interfacial design principles on solid sorbents, creating a synergy between the extrinsic particle surfaces and intrinsic molecular building blocks.
Graphene Readout Silicon‐Based Microtube Photodetectors for Encrypted Visible Light Communication
Authors: Zhang Ziyu , Cai Tianjun , Li Zengxin , Wu Binmin , Zheng Zhi , You Chunyu , Jiang Guobang , Ma Mingze , Xu Zengyi , Shen Chao , Chen Xiang‐zhong , Song Enming , Cui Jizhai , Huang Gaoshan , Mei Yongfeng 
Published: November 2024

AbstractThe implementation of an advanced light receiver is imperative for the widespread application of visible light communication. However, the integration of multifunctional and high‐performance visible light receivers is still limited by device structure and system complexity. Herein, a graphene‐readout silicon‐based microtube photodetector is proposed as the receiver for omnidirectional Mbps‐level visible light communication. The integration of graphene‐semiconductor material systems simultaneously ensures the effective absorption of incident light and rapid readout of photogenerated carriers, and the device exhibits an ultrafast response speed of 75 ns and high responsivity of 6803 A W−1. In addition, the microtube photodetector realizes the omnidirectional light‐trapping and enhanced polarization photodetection. As the receiving end of the visible light communication system, the microtube photodetector achieves a data rate of up to 778 Mbps, a field of view of 140°, and the encrypted visible light communication of polarized light, providing a new possibility for the future development of the internet of things and information security.
Structural Composition and Disassembly Techniques for Efficient Recycling of Waste Lithium‐Ion Batteries
Authors: Zhu Zhiqi , Gao Xu 
Published: November 2024

AbstractLithium batteries represent a significant energy storage technology, with a wide range of applications in electronic products and emerging energy sectors. Concurrently, the high‐value recycling and utilization of waste lithium‐ion batteries (LIBs) has emerged as a prominent area of research. This review commences with an examination of the structural composition, operational methodology, and inherent challenges associated with the recycling process of lithium‐ion batteries. Subsequently, the study conducts a comprehensive examination of the recycling technologies employed in the processing of waste lithium‐ion batteries over the past few years. This encompasses an in‐depth analysis of both primary treatment methodologies, including disassembly, discharge, and classification, as well as advanced treatment techniques such as pyrometallurgy, hydrometallurgy, bio metallurgy technology, and direct regeneration, specifically tailored to LIBs. In addition, this article introduces several process strengthening technologies for traditional treatment methods, identifies current research limitations, and proposes recommendations for the future recycling and reuse of waste lithium‐ion battery cathodes.
Novel Use of Magnesium Hydride to Prevent Peritoneal Adhesions by Regulating Inflammation and Oxidative Stress
Authors: Gong Chuchen , Li Bohui , Wang Yajie , Wang Pei , Xie Qianyin , Liu Enze , Fan Jinchen , Wang Mingsong , Wang Xiansong , Ji Guangyu 
Published: November 2024

AbstractPeritoneal adhesions (PAs) represent a significant clinical challenge, primarily arising from excessive post‐surgical inflammation, which leads to the deposition of fibrin and extracellular matrix, forming adhesive bands that can cause severe complications such as intestinal obstruction and infertility. Current therapeutic options offer limited efficacy in preventing or treating PAs, highlighting the need for new strategies. To address this issue, magnesium hydride (MgH₂) microparticles capable are developed of stable hydrogen (H₂) storage and controlled release to regulate inflammation and promote tissue regeneration. The antioxidant properties, inflammation modulation, and H₂ release profile of MgH₂ are evaluated in vitro, while its anti‐adhesion, angiogenic, and regenerative effects are assessed in vivo using postoperative rat models. These findings demonstrate that MgH₂ significantly mitigates inflammatory dysregulation, reduces oxidative stress, and effectively prevents peritoneal adhesion formation at wound sites. These results suggest that MgH₂ offers a promising therapeutic approach for preventing PAs and supporting beneficial tissue regeneration, presenting a potential clinical solution for postoperative adhesion management.
Protein‐Derived Carbon Dots: Effects of Synthesis Parameters on Retained Protein Function
Authors: Strickland Sara A. , Fourroux Luke A. , McKay McKenna M. , Pappas Dimitri 
Published: November 2024

AbstractNovel‐protein‐derived carbon dots have recently been reported with high biocompatibility, superior spatial resolution, photobleaching resistance, customizability, and no post‐synthesis conjugation requirement. These nanoparticles bring new capabilities in bioimaging and targeted therapeutics. Protein‐based carbon dots contain a carbon core and surface groups from the protein that can retain molecular recognition properties. In this work, a systematic study of synthesis conditions to tune nanoparticle protein function is presented. Bovine serum albumin is used as the model protein to simulate what synthesis parameter alterations yield valuable changes to nanoparticles such as red‐shifted photoluminescence, specific size distribution, and surface chemistry functionalization. The dissociation constant, KD is also calculated, for model BSA‐derived NPs and simulated the 1:1 protein‐ligand binding at equilibrium. It is found that increased temperatures generally led to higher quantum yields and more red‐shifted CDs believed to be due to larger diameters, while nitrogen doping decreased. However, when using microwave radiation, generally NPs are larger and has a 2.5–4.4% increase in nitrogen, resulting in the most red‐shifted and highest quantum yield samples. Oven samples possessed 1.6–17.5x lower KD compared to microwave samples. Understanding the effects of these parameters on CD characteristics enables scientists to rationally design CDs properties for specific applications.
Role of Ag Nanowires: MXenes in Optimizing Flexible, Semitransparent Bifacial Inverted Perovskite Solar Cells for Building‐Integrated Photovoltaics: A SCAPS‐1D Modeling Approach
Authors: Alathlawi Hussain J. , Rabhi Selma , Hidouri Tarak , Adawi Hind , Makin Fadiyah A. , Alsam Amani A. 
Published: November 2024

AbstractSemi‐transparent perovskite solar cells (ST‐PSCs) offer a promising pathway for use in building integrated photovoltaic (BIPV) systems instead of conventional panels’ roofs. Furthermore, their potential for bifacial operation, allowing light absorption from both sides, creates new opportunities for their integration as solar cells windows, and greatly improves energy harvesting capacities. This combination of bifaciality and flexibility enhances their efficiency and adaptability, making them well‐suited for integration into various architectural elements. Herein, in this study, the performance of 40 different configurations of bifacial flexible semi‐transparent inverted perovskite solar cells (BF‐STIPSCs) is explored. Using SCAPS‐1D (version 3.3.11), a 3D‐perovskite (PVK) absorber layer is modeled and combined with polymer‐based electron transport layers (ETLs) such as C60 and BCP, along with innovative hole transport layers (HTLs) including D‐PBTTT‐14, Me‐4PACz, NiOx, PANI, Poly‐TPD, PATAA, SrCuO2, V2O5. Various transparent conductive oxides (TCOs) including IWO, ITO, and FTO, and flexible substrates such as silver nanowires (AgNWs) with two‐dimensional transition carbide (MXene: T2CF2) are also examined for their effects on the cells' bifaciality, transparency, and stability. Among the configurations, PET/Ag NWs:MXenes /SrCuO2/(FAPbI3)0.95(MAPbBr3)0.05/C60/BCP/FTO is identified as a high‐performance structure, achieving a power conversion efficiency (PCE) of ≈26%, along with enhanced resilience to temperature variations. These results hold great promise for the integration of perovskite‐based semitransparent bifacial flexible solar cells into real‐world applications.