bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of Caesarean Delivery in Preterm Premature Rupture of Membranes
Authors: Stancu Samantha Mc Kenzie , Ash Liran Kobi , Smeding Cynthia , Alwan Maisa Abdullah 
Published: April 2019

BACKGROUND: Preterm premature rupture of membranes (P-PROM) exerts a tremendous influence on pregnancy prognosis. Additionally, it is a major public health concern, as the cause of up to 40% of all preterm births.
AIM: The objective of this study was to identify predictors of Caesarean Delivery in singleton pregnancies complicated by P-PROM.
MATERIALS AND METHODS: This is a retrospective observational study of all consecutive singleton P-PROM deliveries (24-37 weeks) over an 18 months at a tertiary referral centre. Pertinent data was collected comprising demographics, obstetric history, pregnancy-associated pathology and delivery from electronic patient records. Univariate statistical analysis comprised Odds Ratio, 95% Confidence interval and Chi-square test with subsequent p-value with statistical significance set at p < 0.05.
RESULTS: A total of 240 women delivered singletons following P-PROM over an 18-month period. Maternal age ranged between 12-41 years with an average age of 28 ± 6.27 years. Vaginal delivery (VD) was the predominant mode of delivery, accounting for 52.9% (n = 127) of deliveries. The following parameters were identified as predictors of Caesarean Section (CS) in P-PROM: vaginal infection (p = 0.04), previous CS (p < 0.0001), primiparity (p = 0.004), gravidity > 5 (p = 0.009), university education (p = 0.0006) and prenatal care (p < 0.0001).
CONCLUSION: The advantage of CS over vaginal delivery is expedited delivery of the distressed fetus, while that of vaginal delivery entails avoiding postoperative morbidity. However, large multicentric randomised-controlled studies are needed to elucidate this dilemma definitively.
Soigner les soignants
Authors: Hibon Benoît 
Published: April 2019

On ne choisit peut-être pas le travail social par hasard, ni de continuer à y travailler. Le professionnel vient peut-être y dénouer les nœuds des autres pour être lui-même « dénoué ». Cette hypothèse rend importante, sinon nécessaire, la supervision dans l’exercice de ces métiers, pour éclairer ce qui se joue et se noue dans les relations, les rencontres.	Le professionnel est seul mais il est aussi en interaction avec d’autres. Cette cohabitation est loin d’aller de soi entre professionnels. Ce qui se joue est complexe, d’autant que s’y trouvent mêlées les personnes accompagnées. Entre elles également : des enjeux. Ceci est à placer dans un contexte général tendant vers la « chalandisation » du secteur, ce qui constitue un enjeu de plus pour les travailleurs sociaux.	Faire appel à un intervenant nécessite de poser les bases pour s’y positionner et donc de définir les différents types d’intervention, ce qui n’empêche pas les professionnels d’apporter des questionnements aux limites de ces cadres. À l’intervenant d’essayer de toujours « soigner les soignants ».	Ainsi, le superviseur est celui qui, de là où il est, écoute et observe ce que les professionnels ont à dire. Puis il leur rend ce qu’il lui semble avoir vu et entendu. Cela afin qu’ils en fassent ce qu’ils souhaitent en fonction de ce qu’ils sont, ensemble, en équipe.
L’analyse des pratiques : inscrire, muser, interpréter
Authors: Gallut Xavier 
Published: April 2019

Cette contribution est destinée à préciser les conditions nécessaires à la mise en place d’un temps d’analyse des pratiques, ainsi qu’à la dynamique symbolisante à l’œuvre, dès lors que des professionnels s’engagent à parler de ce qu’ils font. Il est abordé plus particulièrement la demande et le cadre ; l’inscription, le musement et l’interprétation en référence aux travaux de Balat ; l’aire transitionnelle. En dernier lieu, c’est le problème que pose le mirage de la vérité qui est questionné.
Rencontres
Authors: Broudic Jean-Yves 
Published: April 2019

Le soin et le travail social ne sont pas des services proposés par des professionnels à des patients et usagers. La relation n’est pas à sens unique, des premiers vers les seconds. Elle est bien plus complexe parce qu’elle comporte une dimension inconsciente où du désir est en jeu.	Les réunions d’analyse de pratique et de supervision sont des temps de réflexion collective sur ces enjeux, et elles ne sont pas non plus à sens unique, s’il s’agit de rencontres.
Grandir ensemble
Authors: Verdeil Marie , Guisset Serge 
Published: April 2019

Il est trop d’expériences, de pratiques modestes, de quotidiens minuscules, d’ordinaires si peu banals qui voient le jour et vivent un peu partout et dont personne ne sait rien. Un coup de projecteur s’avère nécessaire afin de découvrir ce qui se fait au cœur de la politique de la Ville dans l’actualité et de susciter des appétits d’agir et des initiatives chez les acteurs et actrices de l’ éducation.	« Grandir ensemble » est le nom d’un lieu d’accueil parents-enfant itinérant, ouvert en 2016 dans deux quartiers d’habitat social de Nîmes, Valdegour et Pissevin. Porté par le collectif Les berceuses de Valdegour, il s’inscrit dans une volonté plus large de créer du lien social au sein des deux quartiers, par le partage sur le sujet de la petite enfance.
Patients’ Satisfaction with Healthcare Delivery in the Gambia: A Case Study of Edward Francis Small Teaching Hospital
Authors: Sanyang Yusupha , Bojang Ismaila , Sarr Francis 
Published: April 2019

The aim of the study was to assess the satisfaction of patients about the services provided at the Edward Francis Small Teaching Hospital (EFSTH) in the Gambia. A cross-sectional study design was used to evaluate how the patients view the healthcare services provided at the EFSTH. The main research question is “what is the satisfaction level of patients about the services provided at the EFSTH”. The SERVQUAL tool was used to collect data from a sample of 250 patients receiving care at the EFSTH. This sample was chosen using the systematic random sampling method. The variable of the study that were measured are satisfaction, expectations and perceptions of patients about the services they received. Data was collected from the outpatient and inpatient department of the hospital. The quantitative data was analyzed using SPSS statistical tool for descriptive statistics, mainly involving the percentages, and the results are presented in tables and charts. The study found out that most of the patients have higher expectations and a low level of perception of the services provided at the EFSTH. There was a low level of patient satisfaction with the hospital services as only 36.8% of the patients strongly agree that they are satisfied with the hospital services provided. The findings also showed that most of the respondents regarded doctors’ services as the most important services provided at the hospital. There is only one service feature (housekeeping) with a positive quality gap score of 2.19667 indicating high quality of services and high patient satisfaction.There is a low level of patient’s satisfaction about the services provided at the EFSTH which is tied to a low level of service quality.
Medical Research Papers and Their Popularization. A Macro- and Micro-Linguistic Qualitative Genre Analysis
Authors: Peppoloni Diana 
Published: April 2019

Communication between the scientific community and the general public is not always effective. There is a meaningful discrepancy that needs to be bridged, mainly because scientific knowledge is produced not only for a restricted specialized community but also for a general target, as part of a crucial social responsibility. The need to fill the gap is even more relevant in medical research as its findings are perceived of direct interest by the public.The process of making specialized knowledge understandable to laypeople is known as popularization (Nash 1990) or popular scientific writing (Calsamiglia 2003), which includes knowledge dissemination in popular magazines, scientific news reports in newspapers and television documentaries. Popularized articles are usually written by journalists who are expert in a specific field and who act as mediators, recontextualizing scientific findings to make them useful and attractive to the large public.In this study we will analyze two medical texts; the first is a research paper about a biomedical topic written and published in English, while the other is a popularization written in Italian and published in the magazine Focus. The purpose of our research is to carry out a qualitative linguistic analysis of the two texts and highlight similarities and differences in their structure and linguistic features, to identify their fundamental constitutive traits, and establish whether they belong to two distinct textual genres or whether one is the adapted version of the other, always referable to the same genre. What we infer from the results of our investigation is that we can assign the two texts to two different genres, having not only different constitutive traits, but also different target audiences and different communicative purposes.
Mechanism of apoptosis induced by Mcl-1 inhibitor UMI-77 on gallbladder carcinoma GBC-SD cells
Authors: Zhang Shengbin , Liu Baoqin , Dong Changcheng , Li Bing 
Published: April 2019

Objective: To investigate the mechanism of apoptosis induced by myeloid cell leukemia-1 (Mcl-1) inhibitor UMI-77 on gallbladder carcinoma GBC-SD cells.Methods: GBC-SD cells were treated with different concentrations of UMI-77. GBC-SD cell proliferation and apoptosis were detected by MTT assay and Annexin V/PI. The expressions of Mcl-1, Bcl-2, Bcl-xL, Bax, Bak, cleaved-caspase 9, cleaved-caspase 3 and cleaved-PARP proteins in GBC-SD cells treated with UMI-77 were detected by Western blotting.Results: The results of MTT showed that different concentrations of UMI-77 had different inhibitory effects on cell proliferation of GBC-SD cells in a dose-dependent and time-dependent manner. Annexin V/PI results showed that the apoptosis rate was increasing gradually with the increase of UMI-77 concentration in a dose-dependent manner. Western blotting results showed that the expression of anti-apoptotic protein Mcl-1 was significantly decreased (p < .05), and the expressions of Bax and Bak proteins were significantly increased respectively (p < .05), but there were no significant changes in the expressions of Bcl-2 and Bcl-xL proteins, and the expression levels of cleaved-caspase 9, cleaved-caspase 3 and cleaved-PARP proteins were significantly increased (p < .05) in 24 h after GBC-SD cells were treated with 10 μmol/L of UMI-77.Conclusions: Mcl-1 inhibitor UMI-77 can induce the apoptosis of GBC-SD cells in a dose-dependent manner through the caspase-mediated endogenous apoptosis pathway. Therefore, Mcl-1 may become a new therapeutic target in the research on gallbladder cancer.
To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds
Authors: Hou Zhihui , Gu Mingjuan 
Published: April 2019

Objective: To investigate the clinical effect of modified closed negative pressure suction technique combined with flap transplantation on the treatment of deep chronic refractory wounds.Methods: During March of 2015 to April of 2018, 52 cases of patients with deep chronic refractory wounds were selected as research objects. They were divided into the control group and the treatment group by use of the random number table method, with 26 cases in each group. Among them, the control group was given conventional debridement combined with flap reconstruction, and the treatment group was treated with modified closed negative pressure suction technique combined with flap transplantation to observe the clinical effect.Results: (1) According to the analysis on the effect of flap transplantation, the excellent and good rate of the treatment group was 92.3%, and in the control group, it was 76.9% (p < .05). (2) According to the statistics, the incidence of complications in the treatment group was lower than that in the control group (p < .05).Conclusions: Modified closed negative pressure suction technique combined with flap transplantation has a good effect on the treatment of deep chronic refractory wounds with fewer complications.
Effect observation of exfoliative cytology combined with CEA, CA125, CA15-3 and CA19-9 examinations in the diagnosis of malignant serous effusion
Authors: Yan Lizhi 
Published: April 2019

Objective: To study the effect of exfoliative cytology combined with CEA, CA125, CA15-3 and CA19-9 examinations on the diagnosis of malignant serous effusion.Methods: 236 cases of patients who were diagnosed as serous effusion during inpatient in our hospital from January of 2015 to January of 2017 were selected as research objects. According to biopsy and pathological examinations, the diagnostic results were cleared that there were 136 cases of patients with benign serous effusion (benign group) and 100 cases of patients with malignant serous effusion (malignant group). Two groups of patients were both given exfoliative cytology combined with CEA, CA125, CA15-3 and CA19-9 examinations for tumor markers to analyze the effect of exfoliative cytology combined with CEA, CA125, CA15-3 and CA19-9 examinations on the diagnosis of malignant serous effusion.Results: The levels of tumor markers CEA, CA125, CA15-3 and CA19-9 in the benign group were all lower than those in the malignant group, and the difference was of statistical significance (p < .05). In addition, exfoliative cytology combined with CEA, CA125, CA15-3 and CA19-9 examinations showed a higher sensitivity, specificity and accuracy than any of the above examinations alone, and the difference was of statistical significance (p < .05).Conclusions: Exfoliative cytology combined with CEA, CA125, CA15-3 and CA19-9 examinations can effectively improve the diagnostic accuracy of malignant serous effusion and is worthy of being spread clinically.
Survey data analysis of the related risk factors of echinococcosis in Inner Mongolia of China and Mongolia
Authors: Zhang Shengbin , Yun Zhelin , E Erdengsuhe , Liu Baoqin 
Published: April 2019

Objective: The aim of the study is to analyze the risk factors of hepatic echinococcosis in mass epidemiological studies in Inner Mongolia of China and Mongolia and provide a basis for related authorities to make appropriate preventive measures.Methods: Eight areas in Inner Mongolia and Zamyn-Üüd region of Mongolia were selected as epidemiological fields. By distributing epidemiological questionnaires to local residents and performing serological examinations and abdominal ultrasound examinations, the data results were collected and analyzed to obtain the risk factors.Results: In this research, there were 7,373 cases of valid data in the area of Inner Mongolia and 1,500 cases in the area of Mongolia. The mean age of the whole survey samples was 52.86 ± 13.90, and the ratio of the female (58.35%) was much higher than that of the male (41.65%). Both univariate analysis and multivariate analysis in this study showed that the female (14.7%) had a higher risk of hepatic echinococcosis than the male (10.9%). From the perspective of profession, children, educators and medical personnel had a lower incidence, herdsmen had the highest positive rate of the disease (15.8%). Living in pastoral areas, having been to pastoral areas, eating uncooked food and drinking unboiled water, raising dogs and surrounding activities of foxes and voles can also increase the risk of positivity.Conclusions: Our findings demonstrate that the most important risk factor of hepatic echinoccosis is unhealthy lifestyles and customs in farmers and herdsmen. It is possible to provide a basis for related authorities to make effective protective measures aiming at hepatic echinococcosis.
Research on the changes and significance of serum RBP4 level in patients with senior coronary heart disease accompanying diabetes mellitus
Authors: Li Qinxue , Ge Biao , Yan Ruijing , Bai Yinlong , Liu Yan 
Published: April 2019

Objective: To explore the significance of serum Retinol binding protein 4 (RBP4) and its relationship with coronary artery lesion in patients with senior coronary heart disease accompanying T2DM by determining the level of serum RBP4 and Gensini score.Methods: 30 cases of patients who were 60 years old above with coronary heart disease accompanying T2DM were selected and included in the experimental group, and 30 cases of patients of 60 years old above with coronary heart disease alone were included in the control group. Both groups of patients were given CAG examinations. In addition, Gensini score was calculated according to different degrees and parts of coronary artery lesion. It was required to record each patient’s age, gender, fasting blood glucose (FPG), triglycerides (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), glycated hemoglobin (HbA1c) and other laboratory examination indexes. ELISA was used to detect the level of serum RBP4 in each group, and statistical analysis was performed to the data in each group.Results: (1) RBP4 level, GS score, FPG and LDL-C in the experimental group were all higher than those in the control group, and the difference was of statistical significance (p < .05). There was no statistically significant difference in age, gender, TC, TG and HDL-C between two groups. (2) RBP4 was positively correlated to FPG and HbA1c. (3) In patients with senior coronary heart disease accompanying diabetes mellitus, HbA1c was positively correlated to GS score, RBP4 and FPG. (4) RBP4 was a risk factor for coronary artery stenosis in patients with senior coronary heart disease accompanying diabetes mellitus.Conclusions: The level of serum RBP4 in patients with senior coronary heart disease accompanying diabetes mellitus is higher than that in patients with coronary heart disease alone, with a deeper degree of coronary artery lesion. The level of serum RBP4 is increased with the degree of lesion deepened in patients with senior coronary heart disease, suggesting that the level of serum RBP4 is expected to be an early predictor of coronary artery lesion for patients with senior coronary heart disease.
Diagnostic value of VCG combined with CDE for acute inferior MI culprit vessel
Authors: Zhao Zhihui , Jiang Li 
Published: April 2019

Objective: To explore the diagnostic value of vectorcardiography (VCG) combined with color Doppler echocardiography (CDE) for acute inferior myocardial infarction (MI) culprit vessel.Methods: A total of 82 patients who had been clinically diagnosed as acute inferior MI and had received coronary arteriography (CAG) were selected as research objects. They received bedside VCG and CDE examinations after admission. Their culprit vessels were analyzed and compared with CAG results to evaluate the diagnostic efficiency.Results: The detection rate of acute inferior MI culprit vessel by VCG combined with CDE was 76.83%, including 18 left circumflex (LCX) branches and 45 right coronary arteries (RCA). The lower left constituent ratio of LCX was 61.11%, which was significantly higher than 20.00% in RCA (p < .05); the lower right constituent ratio of RCA was 71.11%, which was much higher than 11.11% in LCX (p < .05); the sensitivity and the accuracy of RCA culprit vessel judged with frontal plane ST-vector pointing to the lower right quadrant were 71.11% and 53.33% respectively; the diagnostic efficiency of LCX culprit vessel judged with frontal plane ST-vector pointing to the lower left quadrant was 61.11% and 50.00% respectively. The maximum amplitude of the frontal plane in LCX culprit vessel was significantly lower than that in RCA culprit vessel; and the frontal plane vector angle in LCX was significantly greater than that in RCA culprit vessel (p < 0.05).Conclusions: VCG combined with CDE can effectively diagnose acute inferior MI. It has a good diagnostic efficiency by judging culprit vessels according to the frontal plane ST-vector direction.
Limberg flap reconstruction for sacrococcygeal pilonidal sinus disease with and without acute abscess: Our experience and a review of the literature
Authors: Sinnott Catherine J. , Glickman Laurence T. 
Published: April 2019

Background The efficacy of Limberg flap reconstruction for pilonidal sinus with acute abscess remains unclear. This study aimed to compare outcomes after Limberg flap reconstruction for pilonidal sinus disease with and without acute abscess. A secondary objective was to perform a review of the literature on the topic.
Methods A retrospective chart review was conducted of all patients who underwent excision and Limberg flap reconstruction for pilonidal sinus from 2009 to 2018. Patient demographics, wound characteristics, and complication rates were reviewed and analyzed.
Results Group 1 comprised 19 patients who underwent Limberg flap reconstruction for pilonidal sinus disease without acute abscess and group 2 comprised four patients who underwent reconstruction for pilonidal sinus disease with acute abscess. The average defect size after excision was larger in group 2 than group 1 (107.7±60.3 cm2 vs. 61.4±33.8 cm2, respectively). There were no recurrences, seromas or cases of flap necrosis postoperatively. There was only one revision surgery needed for evacuation of a postoperative hematoma in group 1. There were comparable rates of partial wound dehiscence treated by local wound care, hematoma, need for revision surgery and minor infection between group 1 and group 2.
Conclusions Limberg flap reconstruction for pilonidal sinus in the setting of acute abscess is a viable option with outcomes comparable to that for disease without acute abscess. This practice will avoid the pain and cost associated with a prolonged local wound care regimen involved in drainage of the abscess prior to flap reconstruction.
ViSiElse: An innovative visualization R package to ensure behavioral raw data reliability and transparency
Authors: Garnier Elodie Marie , Fouret Nastasia , Descoins Médéric 
Published: April 2019

Background. In recent years, the scientific community encouraged the use of raw data graphs to improve the reliability and transparency of the results presented in papers. However, methods to visualize raw data are limited to one variable per graph and/or only small sample representation. In behavioral science as in many other fields, multiple variables need to be plotted together to allow insights of a behavior and/or process observations. In this paper, we present ViSiElse, a R-package that offers a new approach in raw data visualization.
Methods. This visualization tool was developed as a package of the open-source software R to provide a solution to both the lack of tools allowing visual insights of a whole dataset and the lack of innovative tools for raw data transparency.
Results. ViSiElse grants a global overview of a process by combining the visualization of multiple actions timestamps and all participants in a single graph. Individuals and/or group behavior can easily be assessed and supplementary features allow users to further inspect their data by adding statistical indicators and/or time constraints. ViSiElse allows a global visualization of actions, acquired from timestamps in any quantifiable observations.