bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inter-subject representational similarity analysis reveals individual variations in affective experience when watching erotic movies
Authors: Chen Pin-Hao A. , Jolly Eshin , Cheong Jin Hyun , Chang Luke J. 
Published: August 2019

AbstractWe spend much of our life pursuing or avoiding affective experiences. However, surprisingly little is known about how these experiences are represented in the brain and if they are shared across individuals. Here, we explore variations in the construction of an affective experience during a naturalistic viewing paradigm based on subjective preferences in sociosexual desire and self-control using intersubject representational similarity analysis (IS-RSA). We found that when watching erotic movies, intersubject variations in sociosexual desire preferences of 26 heterosexual males were associated with similarly structured fluctuations in the cortico-striatal reward, default mode, and mentalizing networks. In contrast, variations in the self-control preferences were associated with shared dynamics in the fronto-parietal executive control and cingulo-insula salience networks. Importantly, these results were specific to the affective experience, as we did not observe any relationship with variation in preferences when individuals watched neutral movies. Moreover, these results appear to require multivariate representations of preferences as we did not observe any significant results using single summary scores. Our findings demonstrate that multidimensional variations in individual preferences can be used to uncover unique dimensions of an affective experience, and that IS-RSA can provide new insights into the neural processes underlying psychological experiences elicited through naturalistic experimental designs.
High-density genetic linkage map construction and white rot resistance QTL mapping for Vitis based on restriction site-associated DNA sequencing
Authors: Su Kai , Guo Yinshan , Zhong Weihao , Lin Hong , Liu Zhendong , Li Kun , Guo Xiuwu 
Published: August 2019

AbstractGrape white rot (Coniothyrium diplodiella) is a major fungal disease affecting grape yield and quality. The present study aimed to provide a foundation to improve future grape white rot resistance breeding. To this end, interspecific hybridization was conducted between a white rot resistance cultivar ‘Zhuosexiang’ (Vitus vinifera L. × Vitus labrusca L.), and a susceptible cultivar ‘Victoria’ (Vitus vinifera L.), using 177 hybrid offspring and two parents for restriction site-associated DNA sequencing (RAD-seq) and high-density genetic linkage mapping. Female, male, and integrated map marker numbers were 2501, 4110, and 6249, respectively. The average genetic distance of adjacent markers was 1.25 cM, 0.77 cM, and 0.50 cM. White rot resistance identification of the two parents and 177 individuals was conducted in July and August of 2017 and 2018. Additionally, white rot resistance quantitative trait locus (QTL) mapping was conducted. In total, nine QTLs were detected and located on linkage groups LG1, LG4, LG7, LG12, LG14, and LG15, with overlapping QTLs on LG7 and LG15. Further, three candidate genes that may be responsible for grape white rot resistance were screened. The results will provide an important theoretical reference for future grape white rot resistance breeding.
A Vector Representation of DNA Sequences Using Locality Sensitive Hashing
Authors: Shi Lizhen , Chen Bo 
Published: August 2019

ABSTRACTDrawing from the analogy between natural language and "genomic sequence language", we explored the applicability of word embeddings in natural language processing (NLP) to represent DNA reads in Metagenomics studies. Here, k-mer is the equivalent concept of word in NLP and it has been widely used in analyzing sequence data. However, directly replacing word embedding with k-mer embedding is problematic due to two reasons: First, the number of k-mers is many times of the number of words in NLP, making the model too big to be useful. Second, sequencing errors create lots of rare k-mers (noise), making the model hard to be trained. In this work, we leverage Locality Sensitive Hashing (LSH) to overcoming these challenges. We then adopted the skip-gram with negative sampling model to learn k-mer embeddings. Experiments on metagenomic datasets with labels demonstrated that LSH can not only accelerate training time and reduce the memory requirements to store the model, but also achieve higher accuracy than alternative methods. Finally, we demonstrate the trained low-dimensional k-mer embeddings can be potentially used for accurate metagenomic read clustering and predict their taxonomy, and this method is robust on reads with high sequencing error rates (12-22%).
Sex-associated differences in cytomegalovirus prevention: Prophylactic strategy is associated with a strong kidney function impairment in female renal transplant patients
Authors: Blazquez-Navarro Arturo , Dang-Heine Chantip , Bauer Chris , Wittenbrink Nicole , Wolk Kerstin , Sabat Robert , Witzke Oliver , Westhoff Timm H. , Sawitzki Birgit , Reinke Petra , Thomusch Oliver , Hugo Christian , Babel Nina , Or-Guil Michal 
Published: August 2019

AbstractPost-transplantation cytomegalovirus (CMV) syndrome can be prevented using the antiviral drug (val)ganciclovir. (Val)ganciclovir is typically administered following a prophylactic or a pre-emptive strategy. The prophylactic strategy entails early universal administration, the pre-emptive strategy, early treatment in case of infection. However, it is not clear which strategy is superior with respect to transplantation outcome; sex-specific effects of these prevention strategies are not known. We have retrospectively analysed 540 patients from the multi-centre Harmony study along eight pre-defined visits: 308 were treated according to a prophylactic, 232 according to a pre-emptive strategy. As expected, we observed an association of prophylactic strategy with lower incidence of CMV syndrome, delayed onset and lower viral loads compared to the pre-emptive strategy. However, in female patients, the prophylactic strategy was associated with a strong impairment of glomerular filtration rate one year post-transplant (difference: -12.0±4.2 mL·min-1·1.73m-2, P=0.005). Additionally, we observed a tendency of higher incidence of acute rejection and severe BK virus reactivation in the prophylactic strategy group. While the prophylactic strategy was more effective for preventing CMV syndrome, our results suggest for the first time that the prophylactic strategy might lead to inferior transplantation outcomes in female patients, providing evidence for a strong association with sex.
Trimester-specific Zika virus infection affects placental responses in women
Authors: Lum Fok-Moon , Narang Vipin , Hue Susan , Chen Jie , McGovern Naomi , Rajarethinam Ravisankar , Tan Jeslin J.L. , Amrun Siti Naqiah , Chan Yi-Hao , Lee Cheryl Y.P. , Chua Tze-Kwang , Yee Wearn-Xin , Yeo Nicholas K.W. , Tan Thiam-Chye , Liu Xuan , Haldenby Sam , Leo Yee-sin , Ginhoux Florent , Chan Jerry K.Y. , Hiscox Julian , Chong Chia-Yin , Ng Lisa F.P. 
Published: August 2019

AbstractZika virus (ZIKV) infection during pregnancy is associated with neurologic birth defects, but the effects on placental development are unclear. Full-term placentas from three women, each infected with ZIKV during specific pregnancy trimesters, were harvested for anatomic, immunologic and transcriptomic analysis. In this study, each woman exhibited a unique immune response, but they collectively diverged from healthy controls with raised IL-1RA, IP-10, EGF and RANTES expression, and neutrophil numbers during the acute infection phase. Although ZIKV NS3 antigens co-localized to placental Hofbauer cells, the placentas showed no anatomical defects. Transcriptomic analysis of samples from the placentas revealed that infection during trimester 1 caused a disparate cellular response centered on differential eIF2 signaling, mitochondrial dysfunction and oxidative phosphorylation. These findings should translate to improve clinical prenatal screening procedures for virus-infected pregnant patients.
Predictive factors of response to electrochemotherapy in canine oral malignant melanoma
Authors: Tellado Matías Nicolás , Maglietti Felipe Horacio , Michinski Sebastián Diego , Marshall Guillermo Ricardo , Signori Emanuela 
Published: August 2019

ABSTRACTElectrochemotherapy is a treatment modality which has been increasingly used in veterinary and human medicine for treating cutaneous and subcutaneous tumors. In this prospective work we evaluated the outcome of using electrochemotherapy as a first-line treatment for canine oral melanoma in different stages, with the aim of determining predictive factors of response to the treatment. Mucosal melanoma is the most common cause of oral cancer in dogs. Canine oral malignant melanoma is very similar to human oral melanoma in many aspects, being a very good translational model for studying response to this treatment. Sixty-seven canine patients were treated. Intravenous bleomycin was the preferred drug, and the standard operating procedures for electrochemotherapy were followed. The patients were followed-up for two years. According to WHO criteria, the objective response per stage was: stage I 100%, stage II 89.5%, stage III 57.7% and, stage IV 36.4%. The overall median survival was 7.5 months (2-30 months, mean 9.1 months). Median overall survival of patients in stage I was 16.5 months, in stage II was 9 months, in stage III 7.5 months, and in stage IV 4.5 months. The average number of electrochemotherapy sessions was 1.5 for every stage. The incidence of new metastases among treated patients was 28.4%. Patients in advanced stages, with bone involvement, and caudal location of the tumor had poorer response rates and shorter overall survival times. The treatment greatly improved the quality of life of the patients. Electrochemotherapy is an important technique in the oncological armamentarium against melanoma, and these results can be used to predict human response to this therapy in each stage.
Regulation of neutrophil NADPH oxidase by PSTPIP2 affects bone damage in murine autoinflammatory osteomyelitis
Authors: Kralova Jarmila , Drobek Ales , Prochazka Jan , Spoutil Frantisek , Glatzova Daniela , Borna Simon , Pokorna Jana , Skopcova Tereza , Angelisova Pavla , Gregor Martin , Kovarik Pavel , Sedlacek Radislav , Brdicka Tomas 
Published: August 2019

AbstractAutoinflammatory diseases are characterized by dysregulation of the innate immune system leading to spontaneous inflammation. Pstpip2cmo mouse strain is a well-characterized model of this class of disorders. Due to the mutation leading to the lack of adaptor protein PSTPIP2, these animals suffer from autoinflammatory chronic multifocal osteomyelitis similar to several human syndromes. Current evidence suggests that it is driven by hyperproduction of IL-1β by neutrophil granulocytes. Here we show that in addition to IL-1β, PSTPIP2 also negatively regulates ROS generation by neutrophil NADPH oxidase. Pstpip2cmo neutrophils display highly elevated ROS production in response to a range of stimuli. Inactivation of NADPH oxidase in Pstpip2cmo mice did not affect IL-1β levels and the autoinflammatory process was initiated with similar kinetics. However, the bone destruction was almost completely alleviated, suggesting that dysregulated NADPH oxidase activity is a key factor promoting autoinflammatory bone damage in Pstpip2cmo mice.
The map and the terroir
Authors: Hegnes Atle Wehn 
Published: August 2019

Purpose
An important requirement when producers apply for protected designation of origin (PDO) or protected geographical indications (PGIs) is to adapt and agree on a concise definition of the geographical boundaries and area of the product. Whereas PDO products must be both strongly ecologically and culturally embedded in the specific area, PGI products are allowed a weaker degree of embeddedness. The research question of this paper is: How are geographical boundaries becoming PDOs and PGIs? The paper aims to discuss these issues.

Design/methodology/approach
The analysis is based on diverse forms of empirical material. Document studies of laws, policy documents, etc. have been analyzed to uncover what kind of measures and concepts that have been important for implementation of the scheme in Norway. Interviews with producer organizations have involved the persons responsible for working out product regulations in producer organizations. Interviews have also been conducted with key informants representing public administrative bodies administering the regulation. All interviews have been semi-structured.

Findings
The analysis identifies a set of important conditions for the boundary work of PDO-PGI in Norway. The conditions can generally be said to be characterized by a weak understanding of the food-people-places nexus and a strong reliance on instrumentalised system logic in how to deal with the map-nature dimension in boundary work. The short answer to the research question is that geographical boundaries are becoming PDO and PGI through controversies.

Originality/value
The controversies are characterized by what is defined as cultural adaptation work. The actors overall adaptation work is understood as the sum of the practices that takes place in the interplay between people’s translations of language and knowledge, reorganization of social relationships and transformation of materiality. The interplay is embedded in the tension between the global and the local, the old and the new and results in both intended and unintended consequences.
Efficiency analysis of Indian banking industry over the period 2008–2017 using data envelopment analysis
Authors: Tamatam Roopteja , Dutta Pankaj , Dutta Goutam , Lessmann Stefan 
Published: August 2019

Purpose
The purpose of this paper is to estimate the relative efficiencies of banks of the Indian domestic banking sector by employing various models of data envelopment analysis (DEA) using the panel data of the recent decade (2008–2017). The paper provides a comparative analysis of these models based on the efficiency outputs. It compares the performance of banks based on their ownership and sizes and studies the decade-long trend of productivity using Malmquist indices.

Design/methodology/approach
This paper estimates overall technical, pure technical and scale efficiencies of 21 public sector banks and 17 private banks. It compares the descriptive statistics of efficiency estimates found out through 18 different DEA models and compares them using two non-parametric statistical tests. It studies the difference in efficiencies based on ownership and size by applying the same statistical tests. It employs the Malmquist index method to study the technological and technical progress in the banks’ productivity over the decade of FY 2008–FY 2017.

Findings
During FY 2016–2017, only 9 out of 38 banks were overall technically efficient with the whole sample having a mean overall technical inefficiency of 5 percent with scale inefficiency contributing more than pure technical inefficiency. The comparative study ascertains that private sector and public sector banks (PSBs) possess efficiencies that are similar based on super-efficiency slack-based model – variable returns to scale and non-oriented, a model that the authors argue to be the most suitable for the real-life business banking scenarios whereas the private sector banks possess better efficiency than the PSBs. The Malmquist indices prove that private sector banks have a higher increase in productivity based on both technological progress and efficiency improvements whereas PSBs had a loss of efficiency and comparatively less improvement in technology.

Research limitations/implications
This study has a limitation of choosing a single model of inputs and outputs. Improved insights can be drawn by employing more models based on different inputs and outputs. Further, relevance of each input and output can be examined using a regression-based feedback mechanism (Ouenniche and Carrales, 2018). The influence of environmental factors on the efficiencies can be studied using second-stage regression models and the relationship between efficiency scores and financial ratios can be examined.

Originality/value
This study is based on the panel data of the recent decade (2008–2017) and provides insights into the efficiency scenario of the Indian banking industry and how it changed over the past decade, to the leadership of banks, the banking regulators and the policy makers. The comparative analysis of DEA models based on a sample of Indian banks is first of its kind in the Indian context and helps the researchers to select an appropriate model and delve into further research on the same.
The potency of recycled aggregate in new concrete: a review
Authors: Anike Emmanuel Ejiofor , Saidani Messaoud , Ganjian Eshmaiel , Tyrer Mark , Olubanwo Adegoke Omotayo 
Published: August 2019

Purpose
This paper aims to review the effect of using recycled aggregates (RA) on the properties of recycled aggregate concrete (RAC) following the steady rise in global demand for concrete and the large generation of construction and demolition waste.

Design/methodology/approach
This study reviewed relevant literature of research work carried out by previous researchers, leading to a deeper understanding of the properties of both RA and RAC. The properties of RA and RAC reported in the various studies were then compared to their corresponding natural aggregate (NA) and natural aggregate concrete, as well as the specifications provided in different codes of practice. In addition, the mix design methods appropriate to RAC and the cost implication of using RA were reviewed.

Findings
Findings show that the contribution of RA to strength appears inferior in comparison to NA. The shortcoming is attributed to the mortar attached to the RA, which raises its water absorption capacity and lowers its density relative to those of NA. However, it has been reported that the use of regulated quantity of RA, new mixing and proportioning methods, the addition of admixtures and strengthening materials such as steel fibres, can improve both mechanical and durability properties of RAC. Cost evaluation also showed that some savings can be realized by using RA instead of NA.

Originality/value
This research serves as a guide for future works and suggests that the use of RA as aggregate in new concrete is technically possible, depending on the mix design method adopted.
Critical success factors for building information modelling (BIM) implementation in Hong Kong
Authors: Chan Daniel W.M. , Olawumi Timothy O. , Ho Alfred M.L. 
Published: August 2019

Purpose
Some initiatives have been proposed and implemented to facilitate successful project delivery and improve coordination and collaboration in the design, construction and management phases of project development. Building information modeling (BIM) is one of those initiatives that, though recent, however, have made a significant impact on the construction industry in some countries. The paper aims to discuss this issue.

Design/methodology/approach
This paper aims to explore the critical success factors for BIM implementation in the architecture, engineering and construction industry of Hong Kong through a mixed research method (structured empirical questionnaire survey and expert interviews).

Findings
The most influential success factor relates to the client’s acceptance with BIM projects, proper organizational structure to support a BIM system within the company and financial aid from the government to set up the BIM system. The expert interviewees also stressed the need for willingness from project staff members to learn and utilize BIM.

Practical implications
This study has contributed to the establishment of more practical and effective strategies for ensuring full adoption of BIM in Hong Kong. Practical recommendations for enhancing BIM adoption in the construction industry were highlighted.

Originality/value
This study has established the key drivers leading to the success of BIM implementation in Hong Kong, as well as in the perspective of construction experts on how to enhance its uptake in construction projects.
A Godunov type method determining boundary conditions to predict the transient heat transfer in an expanding combustion chamber
Authors: Hu Chaobin , Zhang Xiaobing 
Published: August 2019

Purpose
This paper aims to improve the reliability of numerical methods for predicting the transient heat transfers in combustion chambers heated internally by moving heat sources.

Design/methodology/approach
A two-phase fluid dynamic model was used to govern the non-uniformly distributed moving heat sources. A Riemann-problem-based numerical scheme was provided to update the fluid field and provide convective boundary conditions for the heat transfer. The heat conduction in the solids was investigated by using a thermo-mechanical coupled model to obtain a reliable expanding velocity of the heat sources. The coupling between the combustion and the heat transfer is realized based on user subroutines VDFLUX and VUAMP in the commercial software ABAQUS.

Findings
The capability of the numerical scheme in capturing discontinuities in initial conditions and source terms was validated by comparing the predicted results of commonly used verification cases with the corresponding analytical solutions. The coupled model and the numerical methods are capable of investigating heat transfer problems accompanied by extreme conditions such as transient effects, high-temperature and high-pressure working conditions.

Originality/value
The work provides a reliable numerical method to obtain boundary conditions for predicting the heat transfers in solids heated by expanding multiphase reactive flows.
Eulerian–Eulerian multi-phase RPI modeling of turbulent forced convective of boiling flow inside the tube with porous medium
Authors: Azadbakhti Reza , Pourfattah Farzad , Ahmadi Abolfazl , Akbari Omid Ali , Toghraie Davood 
Published: August 2019

Purpose
The purpose of this study is simulation the flow boiling inside a tube in the turbulent flow regime for investigating the effect of using a porous medium in the boiling procedure.

Design/methodology/approach
To ensure the accuracy of the obtained numerical results, the presented results have been compared with the experimental results, and proper coincidence has been achieved. In this study, the phase change phenomenon of boiling has been modeled by using the Eulerian–Eulerian multi-phase Rensselaer Polytechnic Institute (RPI) wall boiling model.

Findings
The obtained results indicate using a porous medium in boiling process is very effective in a way that by using a porous medium inside the tub, the location of changing the liquid to the vapor and the creation of bubbles, changes. By increasing the thermal conductivity of porous medium, the onset of phase changing postpones, which causes the enhancement of heat transfer from the wall to the fluid. Generally, it can be said that using a porous medium in boiling flows, especially in flow with high Reynolds numbers, has a positive effect on heat transfer enhancement. Also, the obtained results revealed that by increasing Reynolds number, the created vapor phase along the tube decreases and by increasing Reynolds number, the Nusselt number enhances.

Originality/value
In present research, by using the computational fluid dynamics, the effect of using a porous medium in the forced boiling of water flow inside a tube has been investigated. The fluid boiling inside the tube has been simulated by using the multi-phase Eulerian RPI wall boiling model, and the effect of thermal conductivity of a porous medium and the Reynolds number on the flow properties, heat transfer and boiling procedure have been investigated.