bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using Borehole Image Logs to Refine Reservoir Architecture for Carbonate Reservoir Models, Korolev Field, Republic of Kazakhstan
Authors: Bishop J. W. , Playton T. , Bibolova A. , Correa Mora F. , Sargunanov M. , Hanschitz M. 
Published: November 2024

Abstract
The architecture of carbonate reservoirs can be complex due to depositional profiles with variable, locally steep dips, and to changes in stratal geometries through time resulting from the interplay of accommodation and carbonate sediment production. Capturing this architecture in reservoir models is important for constraining the geometry of flow units and baffles and for distributing reservoir quality. Where seismic interpretation is uncertain or core is limited, borehole image logs can provide valuable information to better constrain architecture.
This study focuses on Korolev Oil Field, a late Paleozoic isolated carbonate platform in the Pricaspian Basin, Republic of Kazakhstan, and illustrates how borehole image logs can be used to refine the interpretation of horizon tops and facies boundaries for input into reservoir models. Bed dips interpreted from image logs provided useful quantitative information, and trends in dip datasets were revealed using plots of cumulative dip azimuth and magnitude. Integration of bed dip data with image log facies, seismic mapping, core description, biostratigraphy, and conventional logs helped identify the orientation of depositional slopes, the boundary between platform and slope facies, and the position of differential compaction related to antecedent platform margins. This updated reservoir architecture has changed the interpretation of facies (slope vs. platform) and horizons to which productive zones in some wells are attributed and has therefore impacted the distribution of reservoir quality in the model. This study underscores the value of commonly under-utilized bed dip interpretations for constraining carbonate reservoir architecture. Integration of bed dip trends from borehole image logs with other available datasets improved the selection of well tops, the interpretation of surfaces, and the position of facies boundaries, all of which are critical static reservoir model inputs.
Tailoring Petroleum Reservoir Simulation Techniques for Modeling Uranium In-Situ Leaching Process
Authors: Umurzakov Y. , Meiman A. , Nurkas A. , Kurmankulov A. , Bigeldiev A. B. , Kuvanyshev A. , Amangaliyev B. , Zhabagenov M. , Yorillo A. , Oppeneau T. 
Published: November 2024

Abstract
Uranium is crucial to the nuclear fuel industry, with Kazakhstan providing about 45% of the global supply, mainly through in-situ leaching (ISL) mining methods. ISL involves injecting a leaching agent to dissolve uranium oxides, which are then extracted as a solution. Optimizing acid volumes for uranium extraction while minimizing environmental impact is essential for improving production efficiency. In this paper we introduce a solution using a high-resolution hydrodynamic simulator to model acid injection, enabling a detailed analysis of acid sweep efficiency at well and cell scales. We also developed industry-specific metrics, including pH, the relationship between the cumulative volume of solution injected (L) and the rock mass within a region (S), and acid-to-uranium ratio, for comprehensive evaluation. As proof of concept, the simulated pH of produced solution closely matches measured values, with minor deviations caused by unaccounted acid-rock reactions. The next step is to integrate a reactive transport model to improve chemical reaction accuracy. Custom Python scripts provide flexibility in managing injection schedules and acid concentrations. The framework tracks acid transport from injection to production wells, offering insight into reservoir dynamics. This work enhances uranium mining efficiency while promoting sustainable growth in the industry.
Asset and Materials Data Enrichment Automation using Computer Vision and Large Language Model
Authors: Ispayev S. , Khamzin N. , Revkova O. , Uanassov B. , Sison M. 
Published: November 2024

Abstract
In 2021, Tengizchevroil (TCO) initiated a pivotal standardization of business processes, data, and technology in several directions, particularly in asset management and materials management in line with Chevron’s enterprise program. Thus, digital solutions were aimed at boosting competitive performance, increasing reliability, preventing failures, managing risk and minimizing the lifecycle cost of surface assets. The central foundation for successful implementation of these solutions is high-quality data management, achieved through the automation of data clean-up and enrichment procedures using Computer Vision (CV) and Large Language Model (LLM) technologies.
The primary challenge faced was the significant amount of missing data in the existing ERP system. To rectify this historical issue, CV and LLM technologies were employed to reduce costs and enhance quality. The complexity of the project was heightened by the need to convert data from scanned files (PDFs) into a computer-friendly JSON format using a CV tool. The resulting deeply nested JSONs were then parsed into structured datasets and allocated to corresponding objects in the ERP system through a reliable LLM.
Fifteen AI models were trained until the suitable ones were found. As a result, approximately 40,000 rows of data were gathered to enrich relevant attributes and characteristics of surface assets and materials. This innovative approach saved 100 working days for eight data analysts with engineering backgrounds, who typically process 50 attributes per day. Much fruitful work has been done on research to obtain the first results appeared in the ERP system.
Freedom of Choice in the United States: Patient Autonomy is Driving Decision-Making in Bariatric Surgery
Authors: Lutfi Rami , Mitko John , Habib Peter , Chaconas Christen 
Published: November 2024

Abstract

Introduction:
Obesity is a global epidemic affecting over 650 million adults, with bariatric surgery emerging as a potent intervention for achieving long-term weight loss and mitigating associated comorbidities. [1] Among the various surgical options, sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are widely performed in the United States. However, optimal surgical selection remains contentious, especially considering the increasing prominence of patient autonomy in healthcare decisions.
Methods
This prospective study, conducted from May 2021 to May 2022, included adults with obesity who were candidates for SG or RYGB. Patients completed a survey regarding their surgical choices and referral sources before receiving standardized education about both procedures. Patients with diabetes were subsequently presented with an evidence-based calculator predicting individual remission rates for diabetes post-surgery. Choices were compared pre- and post-consultation.
Results
Of the 429 patients surveyed, 74.1% had a pre-determined surgical choice, with SG being preferred by 81.4%. The majority of choices were influenced by internet searches. Post-education, despite a significant proportion of diabetic patients receiving alternate recommendations based on the evidence calculator, only 34% altered their initial choice.
Discussion
Findings indicate that patient decisions regarding bariatric surgery are heavily influenced by non-evidence-based internet sources, with a pronounced resistance to altering choices even when presented with objective data. Notably, perceived safety of procedures appears to outweigh considerations of diabetes remission rates.
Conclusions
The pervasive influence of the internet on surgical decision-making poses challenges for healthcare providers striving to balance patient empowerment with evidence-based recommendations. As patients often arrive with pre-determined surgical options, more effective strategies are needed to navigate these complex dynamics to enhance patient satisfaction and optimize surgical outcomes.
The longitudinal relationships of Problematic social media use, Self-transcendence Values and School Adaptation：A two-wave study
Authors: Li Ting , Xie Jiaqiong , Shan Yanjie , Chen Ke 
Published: November 2024

Abstract

This study aims to explore the temporal dynamics of the relationships between problematic social media use(PSMU), self-transcendence values, and school adaptation among college students. Methods: This study employed longitudinal cross-lagged analysis and structural equation modeling to investigate whether there is a mutual influence among PSMU, self-transcendence values, and school adaptation. Additionally, the study explored whether these variables serve as intermediaries in the associations between the other two variables. Results: 2668 students were longitudinally followed up for two-wave.The results indicated PSMU predicted self-transcendence values and school adaptation 6 months later; self-transcendence values predicted PSMU and school adaptation 6 months later; and school adaptation predicted self-transcendence values and PSMU 6 months later. Moreover, each of them plays a mediating role in the association between the other two variables. Conclusions: These results support and expand the Self-worth Theory and Self-determination Theory that there is a bidirectional relationship between PSMU, self-transcendence values, and school adaptation. This result has implications for helping college students adapt to college life and reduce PSMU.
“There is no need to leave the beach to test”: A qualitative study of HIV self-testing knowledge and acceptability of HIV self-test kit distribution among social networks of fishermen in western Kenya
Authors: Lewis-Kulzer Jayne , Olugo Phoebe , Gutin Sarah A. , Kwena Zachary A. , Nishimura Holly , Thorp Marguerite , Agot Kawango , Ayieko Benard , Bukusi Elizabeth A. , Oluoch Lennah , Angawa David , Thirumurthy Harsha , Camlin Carol S. 
Published: November 2024

Abstract

Background
HIV self-testing (HIVST) can improve HIV testing uptake by offering convenience and privacy. Yet HIVST accessibility and uptake remain limited in Lake Victorias beach communities where HIVST holds promise to address many barriers highly mobile populations of men in fishing communities face. We assessed HIVST knowledge and acceptability among highly mobile fishermen, a high priority population for HIV prevention and treatment, participating in a social network-based study (“Owete”; NCT04772469) to promote HIV testing, prevention, and treatment in Kenya.
Methods
Sixty-five in-depth baseline interviews (IDIs) and two focus group discussions (FGDs) were conducted at study baseline from December 2021 to June 2022 with fishermen, including 30 who were social network-central men recruited as HIVST “promoters” from three fishing communities along Lake Victoria, Kenya. Fishermen were purposively-sampled based on study arm, community and age (18–34 and 35+) for interviews exploring HIVST knowledge, perceived benefits, and concerns. IDIs and FGDs were audio-recorded, translated/transcribed into English and inductively-coded and analyzed by six researchers using a framework approach.
Results
Nearly all participants had heard about HIVST and expressed willingness to self-test. Almost half reported learning about HIVST for the first time through the Owete study. Perceived benefits of self-testing included privacy, convenience, and being able to learn one’s status with the freedom to choose when and where to test, which minimized stigma and work interruptions. Few participants had used HIVST prior to joining Owete, all of whom reported ease of use. Potential barriers to HIVST included fear of HIV-seropositive results, feeling unsure about how to use HIVSTs, and fear of stigma if a HIVST was discovered. Nearly all Owete promoters indicated willingness to distribute HIVST to help their peers know their status. Promoters stressed the importance of approaching HIVST discussions strategically and thoughtfully to garner trust and engagement, and felt they needed training to answer HIVST questions.
Conclusion
While few fishermen had ever used HIVST, this study found high awareness, positive perceptions, and substantial willingness to use and distribute HIVST to other men. The “promoter” model, with known peers engaged in disseminating HIVST information and test kits, shows promise for engaging men in testing.
Molecular Characterization and Cuticalar Stomatal Anatomy of Punica Granatum L. Cultivars Study in Dohuk Governorate
Authors: Sinjare Dalal Y. Kh. , Abdulrahman Shamiran S. , Khalid Nizek S. , Ismail Rizgar Y. , Naeem Muhammad Yasir , Selamoglu Zeliha , Isayev Gani , Ahmed Aveen M. N. 
Published: November 2024

Abstract

The pomegranate (Punica granatum L.) has a rich history of cultivation and is renowned for its beneficial properties and nutrient-dense fruits. Native to Central Asia, particularly Iran, Punica granatum has spread to various parts of the world, including Mediterranean countries, Russia, Japan, India, Afghanistan, Pakistan, California, and China. The pomegranate has garnered increasing global interest due to its high nutritional value, as well as its ornamental, industrial, and medicinal benefits. Identifying molecular markers that are less affected by environmental conditions is crucial for measuring genetic diversity among pomegranate cultivars and assisting breeders in selecting and developing genotypes with higher quality and consistency. This study aimed to explore the genetic diversity and stomatal characteristics of nine pomegranate cultivars collected from various locations in Duhok Governorate, Kurdistan Region/Iraq. Genetic diversity was assessed using a combination of molecular methods, including Start Codon Targeted (SCoT) markers, SRAP markers, and the Internal Transcribed Spacer (ITS) gene region, trnG-trnS gene, and 18S–28S rDNA intergenic spacer. The ITS region yielded a product of 700 bp, the trnG-trnS gene was 580 bp, and the 18S–28S rDNA intergenic spacer was 854 bp. Digestion of the trnG-trnS gene with the restriction enzyme HaeIII produced a single amplicon of approximately 490 bp across all samples. The results demonstrated that both SCoT and SRAP markers were effective for analyzing genetic diversity in pomegranates. Additionally, the stomatal structure analysis revealed significant variability among cultivars, with consistent internal structures observed across the cultivars. However, measurements of stomatal components varied depending on the growing location. This study highlights the wide genetic diversity among pomegranate cultivars and the impact of environmental factors on stomatal characteristics.
Kinematic Source Rupture on Listric Faults for the 2024 Noto Peninsula, Japan, Earthquake (Mw 7.5) Estimated from Near-Field Strong-Motion Waveforms
Authors: Guo Yujia , Miyakoshi Ken , Sato Toshiaki 
Published: November 2024

Abstract

On January 1, 2024, an Mw 7.5 reverse-fault earthquake occurred along the submarine active faults just offshore of the Noto Peninsula in central Japan. This earthquake is one of the largest inland crustal earthquakes that ever recorded in Japan. We performed inversions of near-field strong-motion waveforms (0.05–0.25 Hz) to investigate the kinematic rupture process of this earthquake. For the inversions, we assumed listric fault planes, where the dip angles are steeper near the seafloor and become gentler with increased depth, based on the location of the submarine fault offsets, the structure at shallow depths revealed by seismic reflection surveys, and the relocated aftershock distribution at deep depths. To constrain our kinematic source model, we also utilized geodetic information published by the Geospatial Information Authority of Japan. We identified that the rupture process had three phases. The first phase was the initial rupture with a small slip of ~ 2 m around the rupture initiation area. After several seconds, the second and third phases, which were the main ruptures, propagated in the southwest and northeast directions, respectively. During the second and third phases, five large slip areas with average slips of 5–6 m significantly contributed to the strong-motion waveforms. By forward-simulating the geodetic data, we found that the rupture at shallow depths included an oblique component close to a right-lateral component and that, in the eastern part of the source region, the rupture transferred from a southeastward-dipping fault to a northwestward-dipping fault. The listric fault with high dip angles at shallow depths is better than a planar fault with a single dip angle for accurately modeling the fault slip near the surface and the coseismic displacement close to the fault trace during the reverse-fault earthquake.
A duplex HiFi-LAMP assay for screening of two novel human circoviruses HCirV-1 and HCirV-2
Authors: Xu Aijuan , Zhang Min , Chen Xin , Wan Zhenzhou , Zhao Yongjuan , Wang Jian-Hua , Zhang Chiyu 
Published: November 2024

Abstract

Circoviruses belong to the family Circoviridae, which is classified into two genera, Circovirus and Cyclovirus. Some circoviruses have been identified in various organisms and/or their fecal samples and might be associated with diseases in their hosts. However, few circoviruses are reported in human. Recently, two novel circoviruses, HCirV-1 and HCirV-2, were identified in human through next-generation sequencing and are suspected to be associated with liver diseases, particularly among immunosuppressed patients. They are defined as the species of Circovirus human in the family Circoviridae. Given the potential association of these viruses with liver diseases, as well as their small virion size and possible resistance to inactivation, the presence of both viruses in blood may raise biosafety concerns for plasma derivatives. Therefore, to investigate the prevalence of both new human viruses is essential, which needs a rapid, accurate, and specific assay for the detection and screening of these two viruses. In this study, we developed a duplex HiFi-LAMP assay for simultaneous detection of HCirV-1 and HCirV-2. The assay exhibits high sensitivity with LOD of 64 and 49 copies per 25 µL reaction for HCirV-1 and HCirV-2, respectively. The assay demonstrated a rapid reaction time of 35 minutes while enabling simultaneous detection of both HCirV-1 and HCirV-2. Clinical screening test showed that neither HCirV-1 nor HCirV-2 were detected among 875 patients with infection of HBV, HIV-1 or other viruses.
NKX6.3 modulation of mitotic dynamics and genomic stability in gastric carcinogenesis
Authors: Yoon Jung Hwan , Kim Jeong-Kyu , Eun Jung Woo , Ashktorab Hassan , Smoot Duane T. , Nam Suk Woo , Park Won Sang 
Published: November 2024

Abstract

Background
Gastric cancer remains a significant global health challenge, characterized by poor prognosis and high mortality rates. Mitotic integrity and genomic stability are crucial in maintaining cellular homeostasis and preventing tumorigenesis. The transcription factor NKX6.3 has emerged as a potential regulator of these processes in gastric epithelial cells, prompting an investigation into its role in gastric cancer development.
Methods
We employed a combination of in vitro and in vivo techniques to elucidate the impact of NKX6.3 depletion on mitotic dynamics and genomic stability in gastric epithelial cells. Quantitative real-time PCR and Western blot analyses were conducted to assess the expression of mitosis-related genes and proteins. Flow cytometry was utilized to evaluate cell cycle distribution, while immunofluorescence microscopy enabled the visualization of mitotic abnormalities. Statistical analyses, including Student's t-test and ANOVA, were performed to determine the significance of our findings.
Results
Our results demonstrate that NKX6.3 depletion leads to significant mitotic defects, characterized by increased chromosome misalignment and lagging chromosomes during anaphase. These abnormalities corresponded with elevated levels of genomic instability markers, indicating compromised genomic integrity. Furthermore, the loss of NKX6.3 resulted in altered expression of key regulatory proteins involved in mitosis and DNA repair pathways, suggesting a mechanistic link between NKX6.3 and the maintenance of genomic stability in gastric epithelial cells. Depletion of NKX6.3 resulted in accelerated cell cycle progression and the formation of abnormal mitotic figures, leading to genomic instability characterized by increased DNA content and structural abnormalities. In both in vitro and xenograft models, the depletion of NKX6.3 significantly upregulated AurkA and TPX2, which correlated with gains in DNA copy number. An inverse relationship was observed between NKX6.3 expression and the levels of AurkA and TPX2 in human gastric cancer tissues.
Conclusions
This study highlights the essential role of NKX6.3 in regulating mitotic integrity and genomic stability in gastric carcinogenesis. The findings suggest that targeting NKX6.3 may offer a novel therapeutic strategy for improving treatment outcomes in gastric cancer by restoring mitotic fidelity and genomic stability.
Trial registration
This study was not registered.
Development and Validation of a Framework for Registration of Whole-Mount Radical Prostatectomy Histopathology with Three-dimensional Transrectal Ultrasound
Authors: Jager Auke , Zwart Marije J. , Postema Arnoud W. , Kroonenberg Daniel L. , Zwart Wim , Beerlage Harrie P. , Oddens J. R. , Mischi Massimo 
Published: November 2024

Abstract

Purpose
Artificial intelligence (AI) has the potential to improve diagnostic imaging on multiple levels. To develop and validate these AI-assisted modalities a reliable dataset is of utmost importance. The registration of imaging to pathology is an essential step in creating such a dataset. This study presents a comprehensive framework for the registration of 3D transrectal ultrasound (TRUS) to radical prostatectomy specimen (RPS) pathology.
Methods
The study enrolled patients who underwent 3D TRUS and were scheduled for radical prostatectomy. A four-step process for registering RPS to TRUS was used: image segmentation, 3D reconstruction of RPS pathology, registration and ground truth calculation. Accuracy was assessed using a target-registration error (TRE) based on landmarks visible on both TRUS and pathology.
Results
20 Sets of 3D TRUS and RPS pathology were included for analyses. The mean TRE was 3.5 mm, ranging from 0.4 to 5.4 mm.
Conclusion
The framework proposed in this study accomplishes precise registration between prostate pathology and imaging. The methodologies employed hold the potential for broader application across diverse imaging modalities and other target organs.