bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationships between family resilience and posttraumatic growth in breast cancer survivors and caregiver burden
Authors: Liu Ye , Li Yuli , Chen Lijun , Li Yurong , Qi Weiye , Yu Li 
Published: February 2018

AbstractObjectiveTo examine the relationships between family resilience and posttraumatic growth (PTG) of breast cancer survivors and caregiver burden among principal caregivers in China.MethodsParticipants in this cross‐sectional study comprised 108 women aged 26 to 74 years (M = 49, SD = 9) with early‐stage breast cancer and 108 principal caregivers. Participants were recruited from a comprehensive cancer center of a public hospital in Shandong Province, China. The principal caregivers completed the Shortened Chinese Version of the Family Resilience Assessment Scale and the Chinese Version of the Zarit Caregiver Burden Interview; patients completed the Short Form of the Posttraumatic Growth Inventory and questions designed to obtain sociodemographic information. Hierarchical regression analysis was conducted to assess the adjusted association between family resilience and PTG and caregiver burden, while controlling for sociodemographics.ResultsFamilies showed a slightly elevated level of family resilience since the cancer experience, and patients showed a moderate degree of PTG. Principal caregivers reported moderate burden. The Shortened Chinese Version of the Family Resilience Assessment Scale total score was positively related to the Short Form of the Posttraumatic Growth Inventory total score (β = .28, P < .01) and was negatively related to Zarit Caregiver Burden Interview total score (β = −.28, P < .01).ConclusionsFamily resilience impacts PTG of breast cancer survivors and caregiver burden. Our findings indicated the necessity of interventions to facilitate family resilience, promote PTG among breast cancer survivors, and decrease family members' caregiver burden.
Fitness costs of infection with Serratia symbiotica are associated with greater susceptibility to insecticides in the pea aphid Acyrthosiphon pisum
Authors: Skaljac Marisa , Kirfel Phillipp , Grotmann Jens , Vilcinskas Andreas 
Published: February 2018

AbstractBACKGROUNDAphids are agricultural pests that damage crops by direct feeding and by vectoring important plant viruses. Bacterial symbionts can influence aphid biology, e.g. by providing essential nutrients or facilitating adaptations to biotic and abiotic stress.RESULTSWe investigated the pea aphid (Acyrthosiphon pisum Harris) and its commonly associated secondary bacterial symbiont Serratia symbiotica to study the effect of this symbiont on host fitness and susceptibility to the insecticides imidacloprid, chlorpyrifos methyl, methomyl, cyantraniliprole and spirotetramat. There is emerging evidence that members of the genus Serratia can degrade and/or detoxify diverse insecticides. Therefore, we hypothesized that S. symbiotica may promote resistance to these artificial stress agents in aphids. Our results showed that Serratia‐infected aphids were more susceptible to most of the tested insecticides than non‐infected aphids. This probably reflects the severe fitness costs associated with S. symbiotica, which negatively affects development, reproduction and body weight.CONCLUSIONOur study demonstrates that S. symbiotica plays an important role in the ability of aphid hosts to tolerate insecticides. These results provide insight into the potential changes in tolerance to insecticides in the field because there is a continuous and dynamic process of symbiont acquisition and loss that may directly affect host biology. © 2018 Society of Chemical Industry
Development of drug discovery screening system by molecular interaction kinetics–mass spectrometry
Authors: Obi Naoko , Fukuda Tetsuya , Nakayama Noboru , Ervin John , Bando Yasuhiko , Nishimura Toshihide , Nagatoishi Satoru , Tsumoto Kouhei , Kawamura Takeshi 
Published: February 2018

RationaleDrug discovery studies invariably require qualitative and quantitative analyses of target compounds at every stage of drug discovery. We have developed a system combining molecular interaction analysis and mass spectrometry (LC‐MS) using the principle of nanopore optical interferometry (nPOI) called molecular interaction kinetics–mass spectrometry (MIK‐MS). Since nPOI has high binding capacity, the bond‐dissociated compound can be directly detected using LC‐MS. In this study, we use carbonic anhydrase II (CAII) as a ligand and apply six small compounds as analytes and report the affinity analysis using MIK‐MS.MethodsCAII was immobilized onto a COOH sensor chip using standard amine coupling. A reference surface was prepared by activating and subsequently blocking the surface under identical conditions. An amount of 50 μL of mix solution was injected over the reference channel and sample channel for CAII immobilization. The solutions eluting from the sensor chip were collected from the waste‐line of the SKi Pro system every 30 s. Reconstructed elution samples were then injected into the LC‐MS/MS system.ResultsA mixture containing furosemide, acetazolamide, 4‐sulfamoylbenzoic acid, 5‐(dimethylamino)‐1‐naphthalene sulfonamide (DNSA), sulfanilamide and sulpiride (15 μM each) was injected into the CAII‐immobilized sensor chip, and the fractions eluted from the SKi Pro system were collected and subjected to selected reaction monitoring LC‐MS characterization. Specific results were obtained for acetazolamide, DNSA, furosemide and sulpiride. The results suggest that the association–dissociation curve of a mixed sample can be obtained by one‐time MIK‐MS analysis.ConclusionsSix small‐molecule binders of CAII were analyzed quantitatively using nPOI and MIK‐MS, and the results were compared to published surface plasmon resonance (SPR) results. The nPOI and SPR results show good agreement, confirming the reliability of the analysis. Time‐dependent binding results may be obtained by our MS sensorgram approach. Drugs that meet medical needs in a short period are required; this nPOI‐LC‐MS system is considered an important tool for rapid drug discovery.
Visible Light Driven Photocatalytic Cross‐Coupling Reactions on Nano Pd/ZnO Photocatalyst at Room‐Temperature
Authors: Hosseini‐Sarvari Mona , Bazyar Zahra 
Published: February 2018

AbstractIn this paper, we report a highly efficient photocatalytic activity of nano Pd/ZnO in cross‐coupling reactions including Suzuki‐Miyaura, Hiyama and Buch‐wald‐Hartwig reactions under visible light irradiation at ambient temperatures. This study shows that nano Pd/ZnO is a good photocatalyst under visible light irradiation. The photocatalytic activity of nano Pd/ZnO depends on the irradiation light intensity and wavelength. The results of photocatalysis demonstrate that nano Pd/ZnO, shows good result with high efficiency and selectivity and it can be recycled and reused several times without any significant loss in catalytic reactivity.
Highly Efficient Visible Light Active 2D‐2D Nanocomposites of N‐ZnO‐g‐C3N4 for Photocatalytic Degradation of Diverse Industrial Pollutants
Authors: Kumar Suneel , Kumar Ashish , Kumar Ajay , Balaji Ramachandran , Krishnan Venkata 
Published: February 2018

AbstractIn the drive towards the development of efficient photocatalytic materials for environmental remediation, two dimensional (2D) materials have drawn huge attention in the recent time. Towards this end, we report two dimensional (2D) nanocomposite by loading N‐doped ZnO nanosheets over graphitic carbon nitride (g‐C3N4) nanosheets by hydrothermal synthesis method. As prepared 2D‐2D nanocomposite exhibit excellent photocatalytic activity towards degradation of Rhodamine B (RhB) dye from water under visible light irradiation. Moreover, the optimized nanocomposite with 7 wt% of N‐ZnO nanosheets (GNZ7) shows superior photocatalytic activity for degradation of several industrial pollutants including thiabendazole (TBZ), nitrobenzene (NB) and tetracycline (TC). The photoluminescence studies confirmed the improved interfacial charge separation which profoundly promotes their transfer to the reaction sites and hence responsible for the enhanced photocatalytic activity. In addition, the photocatalytic mechanism has been elucidated using active species trapping experiments which validate that hydroxyl radicals (*OH) and holes (h+) play a vital role in the degradation process. Furthermore, reusability experiments confirm the excellent stability of N‐ZnO‐g‐C3N4 nanocomposites. Hence, it can be summarized that such 2D‐2D nanocomposite have great potential to degrade diverse industrial pollutants and provides new insights for the fabrication of such nanocomposites for various applications.
Merge‐Tree: Visualizing the integration of commits into Linux
Authors: Wilde Evan , German Daniel 
Published: February 2018

AbstractWith an average of more than 900 merges into the Linux kernel per release, many containing hundreds of commits and some containing thousands, maintenance of older versions of the kernel becomes nearly impossible. Various commercial products, such as the Android platform, run older versions of the kernel; due to security, performance, and changing hardware needs, maintainers must understand what changes (commits) are added to the current version of the kernel since the last time they inspected it to make the necessary patches. Current tools provide information about repositories through the directed acyclic graph (DAG) of the repository, which is helpful for smaller projects. However, with the scale and number of branches in the kernel, the DAG becomes overwhelming very quickly. Furthermore, the DAG contains every parents of every commit, while maintainers are more interested in how and when a commit arrives to the official Linux repository. This paper makes 3 contributions: a conversion from DAG to Merge‐Tree, an implementation of a tool built on the Merge‐Tree model, and a user study to evaluate and validate the implementation and model.
Efficacy of platelet transfusion for acute intracerebral hemorrhage among patients on antiplatelet therapy
Authors: Eke Onyinyechi , Shanechi Mercedeh , Gottlieb Michael 
Published: February 2018

Clinical questionIn patients taking antiplatelet therapy, does a platelet transfusion after acute spontaneous primary intracerebral hemorrhage reduce the risk of death or dependence?Article chosenBaharoglu MI, Cordonnier C, Al-Shahi Salman R, et al. Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral hemorrhage associated with antiplatelet therapy (PATCH): a randomized, open-label, phase 3 trial.Lancet2016;387(10038):2605-13.Study objectiveThe primary objective of this study was to investigate whether a platelet transfusion with standard care, compared with standard care alone, reduced death or dependence after intracerebral hemorrhage associated with antiplatelet therapy use.
EARLY REPRESENTATIONS OF FILIAL PIETY IN DYNASTIC HISTORIOGRAPHY: TEXTUAL HISTORY AND CONTENT OFHOU HAN SHUCHAPTER 39
Authors: Eicher Sebastian 
Published: February 2018

AbstractTales of filial piety became a standard element of the annals-biography style of historiography early on. Starting from theSong shu宋書, almost every dynastic history contains a chapter that is devoted to filial men. An early—but often neglected—precursor is Chapter 39 of Fan Ye's 范曄 (398–446)Hou Han shu後漢書. Inspired by his predecessor Hua Qiao 華嶠 (?–293), Fan inserted a chapter on filial men. The chapter was therefore compiled in times when the recommendation system of the Han and especially the recommendation as “filial and incorruptible” (xiaolian孝廉) had lost influence. This paper tries to shed some light on its origins, form, and content, and attempts to distinguish the most common motives that were used to describe filial (xiao孝) behavior in this early stage of its historiographical representation.
Boundary layer fluctuations in turbulent Rayleigh–Bénard convection
Authors: Wang Yin , Xu Wei , He Xiaozhou , Yik Hiufai , Wang Xiaoping , Schumacher Jörg , Tong Penger 
Published: February 2018

We report a combined experimental and numerical study of the effect of boundary layer (BL) fluctuations on the scaling properties of the mean temperature profile$\unicode[STIX]{x1D703}(z)$and temperature variance profile$\unicode[STIX]{x1D702}(z)$in turbulent Rayleigh–Bénard convection in a thin disk cell and an upright cylinder of aspect ratio unity. Two scaling regions are found with increasing distance$z$away from the bottom conducting plate. In the BL region, the measured$\unicode[STIX]{x1D703}(z)$and$\unicode[STIX]{x1D702}(z)$are found to have the scaling forms$\unicode[STIX]{x1D703}(z/\unicode[STIX]{x1D6FF})$and$\unicode[STIX]{x1D702}(z/\unicode[STIX]{x1D6FF})$, respectively, with varying thermal BL thickness$\unicode[STIX]{x1D6FF}$. The functional forms of the measured$\unicode[STIX]{x1D703}(z/\unicode[STIX]{x1D6FF})$and$\unicode[STIX]{x1D702}(z/\unicode[STIX]{x1D6FF})$in the two convection cells agree well with the recently derived BL equations by Shishkinaet al.(Phys. Rev. Lett., vol. 114, 2015, 114302) and by Wanget al.(Phys. Rev. Fluids, vol. 1, 2016, 082301). In the mixing zone outside the BL region, the measured$\unicode[STIX]{x1D703}(z)$remains approximately constant, whereas the measured$\unicode[STIX]{x1D702}(z)$is found to scale with the cell height$H$in the two convection cells and follows a power law,$\unicode[STIX]{x1D702}(z)\sim (z/H)^{\unicode[STIX]{x1D716}}$, with the obtained values of$\unicode[STIX]{x1D716}$being close to$-1$. Based on the experimental and numerical findings, we derive a new equation for$\unicode[STIX]{x1D702}(z)$in the mixing zone, which has a power-law solution in good agreement with the experimental and numerical results. Our work demonstrates that the effect of BL fluctuations can be adequately described by the velocity–temperature correlation functions and the new BL equations capture the essential physics.
Ethnic cartography and politics in Vienna, 1918–1945
Authors: SVATEK PETRA 
Published: February 2018

AbstractIn Vienna, the close of the First World War and the period of the peace negotiations in Paris saw an enormous boom of ethnic-geographic research approaches and ethnic map-making. This process continued with the appointment of the Viennese geographer Hugo Hassinger (1877–1952) to the chair of human geography at the University of Vienna in 1931 and intensified with the establishment of the South East German Research Association and the National Socialist takeover in March 1938. But did the initiatives to create ethnic maps originate with politicians and authorities, or did they come from the scientists themselves? This article argues that scientists embarked upon ethnic geographies on their own initiative. Although political institutions used scientists and their resources for their own, political ends (ethnographic maps served as an important source for the National Socialists in their operations for ethnic consolidation), scientists also mobilized resources from the political sphere for career and disciplinary purposes.
Temporal changes in arthropod activity in tropical anthropogenic forests
Authors: Brandon-Mong G.-J. , Littlefair J.E. , Sing K.-W. , Lee Y.-P. , Gan H.-M. , Clare E.L. , Wilson J.-J. 
Published: February 2018

AbstractArthropod communities in the tropics are increasingly impacted by rapid changes in land use. Because species showing distinct seasonal patterns of activity are thought to be at higher risk of climate-related extirpation, global warming is generally considered a lower threat to arthropod biodiversity in the tropics than in temperate regions. To examine changes associated with land use and weather variables in tropical arthropod communities, we deployed Malaise traps at three major anthropogenic forests (secondary reserve forest, oil palm forest, and urban ornamental forest (UOF)) in Peninsular Malaysia and collected arthropods continuously for 12 months. We used metabarcoding protocols to characterize the diversity within weekly samples. We found that changes in the composition of arthropod communities were significantly associated with maximum temperature in all the three forests, but shifts were reversed in the UOF compared with the other forests. This suggests arthropods in forests in Peninsular Malaysia face a double threat: community shifts and biodiversity loss due to exploitation and disturbance of forests which consequently put species at further risk related to global warming. We highlight the positive feedback mechanism of land use and temperature, which pose threats to the arthropod communities and further implicates ecosystem functioning and human well-being. Consequently, conservation and mitigation plans are urgently needed.
The Power of Some Tests of Correlation
Authors: Williams E. J. 
Published: February 2018

The coefficient of correlation between suitably defined statistics provides a means of testing various parametric hypotheses. The distribution of such coefficients, when the null hypothesis is not true, takes various forms in different applications. In particular, the correlation coefficients used to test hypotheses about the structural parameters in linear functional relations have doubly non-central distributions.For tests of correlation in some typical situations, the curvature of the function defining the power in terms of the parameter in the neighbourhood of the null hypothesis is determined. This curvature is shown to be simply related to that of the function defining the squared correlation coefficient in terms of the parameter, in the neighbourhood of its minimum.
Some Problems in Mathematical Genealogy
Authors: Kendall David G. 
Published: February 2018

After a general review of symmetric reversibility for countable-state continuous-time Markov chains the author shows that the birth-death-and-immigration process is symmetrically reversible and further that it remains so even when the description of the present state is refined to include a list of the sizes of all ‘families’ alive at the epoch in question. This result can be useful in genealogy because the operational direction of time there is the negative one. In view of the symmetric reversibility, some of the questions which face the genealogist can be answered without further calculation by quoting known results for the process with the usual (‘forward’ instead of ‘backward’) direction of time.Further topics discussed include social mobility matrices, surname statistics, and Colin Rogers' ‘problem of the Spruces’.
Brevard Childs and the treasures of darkness
Authors: Cornell Collin 
Published: February 2018

AbstractContemporary biblical studies is populated by ‘comparativists’ and ‘theological interpreters’: scholars who read the Bible in the context of ancient artefacts, and scholars who read it in the context of Christian theology, respectively. These camps relate to one another mostly by feuding – or by mutual avoidance. The Old Testament theologian Brevard Childs is usually taken as a champion in the cause of theological interpretation, and so also as reinforcing one side of the disciplinary division. But under certain conditions, Childs also authorised the use of ancient artefacts (‘the treasures of darkness’) for reading scripture theologically. This article reactivates the latter possibility within Childs’ interpretive programme, especially through two cases studies: the first by Childs himself, when he uses the Sargon Legend to interpret Exodus 2; and the second a reprise of Childs’ procedure, using the Mesha Inscription to interpret 1 Kings 22.
Following John Hejduk's Fabrications: on imagination and reality in the architectural design process
Authors: Anderson Jane , Priest Colin 
Published: February 2018

This paper investigates the interaction between reality and imagination in the architectural design process. It engages with four inter-related inquiries. First, the interplay between reality and imagination in the architectural design process in student design-build live projects. Second, the interplay of reality and imagination for different agents in the architectural design process. Third, how the work of John Hejduk (1929-2000) enables a reappraisal of conceptions of reality and imagination in architectural design. Fourth, we address a live project for The Story Museum in Oxford, UK – a physical architectural space concerned with imaginary spaces – that suggests how an understanding of reality and imagination might be deepened in the architectural design process.The text reappraises the interplay of reality and imagination in architectural design as a cognitive process. There are two aims: to reassess empirical responses and received wisdom about what is real and what is imagined in architectural design; and to reassess the perception of differences between imagination and reality occurring across education and practice. ‘Thing Theory’ is proposed as a conceptual framework which allows us to improve our understanding of how architectural designs emerge, are transformed in the designer's mind, how architects communicate them to others and how they are understood and shared by others. Reference is also made to interviews with prominent architects. The term ‘thing’ was repeatedly used by these architects to describe moments in the design process when a break from reality had occurred. In these moments, subject and object seemed at their most intertwined. This moment is strong because it is so flexible in responding to change and managing complexity. It is also weak because it is a time when the designer tends to neglect vital everyday constraints such as occupation and ethics. However, this is a key moment because it allows possible future realities to emerge.
Q-band cross-coupled dielectric resonator filter using TM mode for satellite application
Authors: Ghadiya Ambrish , Soni Shilpi , Trivedi Keyur 
Published: February 2018

AbstractA new structure of Q-band filter comprising rectangular high-permittivity dielectric resonators (DR) operating at TM11δ mode is introduced. The resonator shows high-quality factor (Q) and wide spurious free window compared with other technologies available at Q-band for realizing filters. Low permittivity ceramic material (quartz) is used as a support for holding DR at the center of the cavity. An eight-pole cross-coupled band-pass filter having a bandwidth of 225 MHz at 38.5 GHz was realized. Resonant coupling structure is introduced to realize cross-coupling in filter. The resonator assemblies were optimized precisely to achieve effective linear frequency drift over temperature of the order of 2 ppm/°C. The filter also survived severe sine and random vibration test for satellite application.
Granzyme B deficiency promotes osteoblastic differentiation and calcification of vascular smooth muscle cells in hypoxic pulmonary hypertension
Authors: Mao Min , Zhang Min , Ge Anqi , Ge Xin , Gu Rui , Zhang Chen , Fu Yao , Gao Jiayin , Wang Xiaoying , Liu Yang , Zhu Daling 
Published: February 2018

AbstractCalcification is a major risk factor for vascular integrity. This pathological symptom and the underlying mechanisms in hypoxic pulmonary artery hypertension remain elusive. Here we report that pulmonary vascular medial calcification is elevated in pulmonary artery hypertension models as a result of an osteoblastic phenotype change of pulmonary arterial smooth muscle cells induced by hypoxia. Notably, inhibiting store-operated calcium channels significantly decreased osteoblastic differentiation and calcification of pulmonary arterial smooth muscle cells under hypoxia. We identified granzyme B, a major constituent of cytotoxic T lymphocytes/natural killer cell granules involved in apoptosis, as the main regulator of pulmonary arterial calcification. Overexpression of granzyme B blocked the mineralization through its effect on store-operated calcium channels in cultured pulmonary arterial smooth muscle cells under hypoxic conditions. Mice with overexpression of granzyme B exposed to hypoxia for 3 weeks showed attenuated vascular calcification and pathological progression of hypoxic pulmonary arterial hypertension. Our findings emphasize the central function of granzyme B in coordinating vascular calcification in hypoxic pulmonary arterial hypertension.