bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eating habits in the population of the Aeolian Islands: an observational study
Authors: La Spina Paolo , Savica Rodolfo , Ciacciarelli Antonio , Cotroneo Masina , Dell’Aera Cristina , Grillo Francesco , Casella Carmela , Fazio Maria Carolina , Trimarchi Giuseppe , Musolino Rosa Fortunata 
Published: December 2018

AbstractObjectiveWe conducted a study to describe food profile, health status and stroke risk factors in the population of the Aeolian Islands.DesignSelf-administrated questionnaires regarding eating habits, health status and stroke risk factors were obtained from a sample of the general Aeolian population. We analysed the difference from common healthy eating habits indicated by the Italian Institute of Nutrition.SettingCurrent evidence finds the Mediterranean diet is a protective factor for cardio- and cerebrovascular diseases. The Aeolian Islands are an interesting study setting because of their peculiarity in the epidemiology of cerebrovascular and neurodegenerative diseases.ParticipantsIndividuals (n586; age range 15–93 years; mean 52 (sd18) years) living in the Aeolian Islands.ResultsWe found low fish consumption in 13·3% and vitamin intake deficiency in 5·8% of participants. A marked excess of saturated fats was observed in 71·0% of participants. Sodium excess was reported almost in half of participants (49·0%). Eating habits were characterized by high consumption of fruits and vegetables, consistent use of olive oil and scanty use of cured meat. Health status as evaluated by the General Health Questionnaire was characterized by ‘normal distress’ level in the majority of participants.ConclusionsStudy findings show the eating habits and health status of the Aeolian people in an interesting setting of low incidence of cerebrovascular disease. This nutrition regimen has been proved to be protective against cerebrovascular disease. Nutrition is likely to contribute to the low incidence of stroke in this population.
ON MORITA EQUIVALENCE AND INTERPRETABILITY
Authors: MCELDOWNEY PAUL ANH 
Published: December 2018

Abstract
In a recent paper, Barrett & Halvorson (2016) define a notion of equivalence for first-order theories, which they call “Morita equivalence.” To argue that Morita equivalence is a reasonable measure of “theoretical equivalence,” they make use of the claim that Morita extensions “say no more” than the theories they are extending. The goal of this paper is to challenge this central claim by raising objections to their argument for it and by showing why there is good reason to think that the claim itself is false. In light of these criticisms, this paper develops a natural way for the advocate of Morita equivalence to respond. However, this response makes her criterion equivalent to mutual faithful interpretability, an already well-known and philosophically contentious barometer of theoretical equivalence.
Concurrent and Lagged Relations between Emotion Regulation and Affect in Adolescents’ Daily Life
Authors: Silva Eliana , Freire Teresa , Faria Susana 
Published: December 2018

AbstractA better understanding of emotion regulation (ER) within daily life is a growing focus of research. This study evaluated the average use of two ER strategies (cognitive reappraisal and expressive suppression) and concurrent and lagged relationships between these two ER strategies and affect (positive and negative affect) in the daily lives of adolescents. We also investigated the role of the same strategies at the trait level on these within-person relationships. Thirty-three adolescents provided 1,258 reports of their daily life by using the Experience Sampling Method for one week. Regarding the relative use of ER strategies, cognitive reappraisal (M = 2.87, SD = 1.58) was used more often than expressive suppression (M = 2.42, SD = 1.21). While the use of both strategies was positively correlated when evaluated in daily life (p = .01), the same did not occur at the trait level (p = .37). Multilevel analysis found that ER strategies were concurrently related to affect (p < .01), with the exception of cognitive reappraisal-positive affect relationship (p = .11). However, cognitive reappraisal predicted higher positive affect at the subsequent sampling moment ( β = 0.07, p = .03). The concurrent associations between cognitive reappraisal and negative affect vary as function of the use of this strategy at the trait level (β = 0.05, p = .02). Our findings highlighted the complex associations between daily ER strategies and affect of a normative sample of adolescents.
Recycled Components in Mantle Plumes Deduced From Variations in Halogens (Cl, Br, and I), Trace Elements, and 3He/4He Along the Hawaiian‐Emperor Seamount Chain
Authors: Broadley Michael W. , Sumino Hirochika , Graham David W. , Burgess Ray , Ballentine Chris J. 
Published: December 2018

AbstractHalogens are primarily located within surface reservoirs of the Earth; as such they have proven to be effective tracers for the identification of subducted volatiles within the mantle. Subducting lithologies exhibit a wide variety of halogen compositions, yet the mantle maintains a fairly uniform signature, suggesting halogens may be homogenized during subduction to the mantle or during eruption. Here we present halogen (Cl, Br, and I), K, noble gas, and major and trace element data on olivines from three seamounts along the Hawaiian‐Emperor seamount chain to determine if the deep mantle source has retained evidence of halogen heterogeneities introduced through subduction. High Ni contents indicate that the Hawaiian‐Emperor mantle source contains a recycled oceanic crust component in the form of pyroxenite, which increases from the 46% in the oldest (Detroit) to 70% in the younger seamount (Koko). Detroit seamount retains mid‐ocean ridge basalts (MORB)‐like Br/Cl and I/Cl, while the Br/Cl and I/Cl of Suiko and Koko seamounts are higher than MORB and similar to altered oceanic crust and dehydrated serpentinite. Helium isotopes show a similar evolution, from MORB‐like values at Detroit seamount toward higher values at Suiko and Koko seamounts. The correlation between pyroxenite contributions, Br/Cl, I/Cl, and 3He/4He indicates that subducted material has been incorporated into the primordial undegassed Hawaiian mantle plume source. The identification of recycled oceanic crustal signatures in both the trace elements and halogens indicates that subduction and dehydration of altered oceanic crust may exert control on the cycling of volatile elements to the deep mantle.
Observed Trends in Global Indicators of Mean and Extreme Streamflow
Authors: Gudmundsson L. , Leonard M. , Do H. X. , Westra S. , Seneviratne S. I. 
Published: December 2018

AbstractThis study investigates global changes in indicators of mean and extreme streamflow. The assessment is based on the Global Streamflow Indices and Metadata archive and focuses on time series of the annual minimum, the 10th, 50th, and 90th percentiles, the annual mean, and the annual maximum of daily streamflow. Trends are estimated using the Sen‐Theil slope, and the significance of mean regional trends is established through bootstrapping. Changes in the indices are often regionally consistent, showing that the entire flow distribution is moving either upward or downward. In addition, the analysis confirms the complex nature of hydrological change where drying in some regions (e.g., in the Mediterranean) is contrasted by wetting in other regions (e.g., North Asia). Observed changes are discussed in the context of previous results and with respect to model estimates of the impacts of anthropogenic climate change and human water management.
Breakup Without Borders: How Continents Speed Up and Slow Down During Rifting
Authors: Ulvrova Martina M. , Brune Sascha , Williams Simon 
Published: December 2018

AbstractRelative plate motions during continental rifting result from the interplay of local with far‐field forces. Here we study the dynamics of rifting and breakup using large‐scale numerical simulations of mantle convection with self‐consistent evolution of plate boundaries. We show that continental separation follows a characteristic evolution with four distinctive phases: (1) an initial slow rifting phase with low divergence velocities and maximum tensional stresses, (2) a synrift speed‐up phase featuring an abrupt increase of extension rate with a simultaneous drop of tensional stress, (3) the breakup phase with inception of fast sea‐floor spreading, and (4) a deceleration phase occurring in most but not all models where extensional velocities decrease. We find that the speed‐up during rifting is compensated by subduction acceleration or subduction initiation even in distant localities. Our study illustrates new links between local rift dynamics, plate motions, and subduction kinematics during times of continental separation.
Global Impacts of Arctic Sea Ice Loss Mediated by the Atlantic Meridional Overturning Circulation
Authors: Liu Wei , Fedorov Alexey V. 
Published: December 2018

AbstractWe explore the global impacts of Arctic sea ice decline in climate model perturbation experiments focusing on the temporal evolution of induced changes. We find that climate response to a realistic reduction in sea ice cover varies dramatically between shorter decadal and longer multidecadal to centennial timescales. During the first two decades, when atmospheric processes dominate, sea ice decline induces a “bipolar seesaw” pattern in surface temperature with warming in the Northern and cooling in the Southern Hemisphere, leading to a northward displacement of the Intertropical Convergence Zone and an expansion of Antarctic sea ice. In contrast, on multidecadal and longer timescales, the weakening of the Atlantic meridional overturning circulation, caused by upper‐ocean buoyancy anomalies spreading from the Arctic, mediates direct sea ice impacts and nearly reverses the original response pattern outside the Arctic. The Southern Hemisphere warms, a Warming Hole emerges in the North Atlantic, the Intertropical Convergence Zone shifts southward, and Antarctic sea ice contracts.
Microphysical Characteristics of an Asymmetric Eyewall in Major Hurricane Harvey (2017)
Authors: Feng Ya‐Chien , Bell Michael M. 
Published: December 2018

AbstractMicrophysical and kinematic structures of major Hurricane Harvey's (2017) asymmetric eyewall are analyzed from ground‐based polarimetric and airborne Doppler radars. New polarimetric observations of differential reflectivity (ZDR) and specific differential phase (KDP) show asymmetric wavenumber‐1 patterns associated with vertical wind shear (VWS) but were shifted azimuthally with respect to the reflectivity (ZH) asymmetry. A ZDR column was found upwind of the ZH maximum in a region with strong updrafts estimated from multi‐Doppler synthesis, with higher values of KDP found cyclonically downwind. Retrieved raindrop size distributions show that azimuthal variations of size and number concentration were determined by both the VWS and the size sorting process. The diameter of raindrops decreases, while the number concentration increases cyclonically downwind of VWS‐induced updrafts due to the differential terminal fall speed of raindrops and strong rotational flow at major hurricane wind speeds.
Cosmic Ray Albedo Neutron Decay (CRAND) as a Source of Inner Belt Electrons: Energy Spectrum Study
Authors: Zhang K. , Li X. , Zhao H. , Schiller Q. , Khoo L.‐Y. , Xiang Z. , Selesnick R. , Temerin M. A. , Sauvaud J. A. 
Published: December 2018

AbstractCosmic Ray Albedo Neutron Decay (CRAND) has been recently confirmed as a source of energetic electrons at the inner edge of the inner belt by the Colorado Student Space Weather Experiment (CSSWE) mission. Here we use observations from the Detection of Electro‐Magnetic Emissions Transmitted from Earthquake Regions (DEMETER) mission, to investigate the CRAND contribution to inner belt electrons quantitatively over a broad energy range (~100–800 keV). Spectral fitting analysis supports the conclusion that CRAND is the most important electron source at the inner edge of the inner belt. For the first time, we show that CRAND is the dominant source of >250‐keV quasitrapped electrons throughout the inner belt and slot region during quiet times. We suggest that additional sources for <250‐keV electrons exist, perhaps from inward transport. In contrast, dynamics of electrons in the inner belt and slot region is dominated by injections during active times.
Observational Evidence of Magnetic Reconnection in the Terrestrial Bow Shock Transition Region
Authors: Wang Shan , Chen Li‐Jen , Bessho Naoki , Hesse Michael , Wilson Lynn B. , Giles Barbara , Moore Thomas E. , Russell Christopher T. , Torbert Roy B. , Burch James L. 
Published: December 2018

AbstractWe report evidence of magnetic reconnection in the transition region of the Earth's bow shock when the angle between the shock normal and the immediate upstream magnetic field is 65°. An ion‐skin‐depth‐scale current sheet exhibits the Hall current and field pattern, electron outflow jet, and enhanced energy conversion rate through the nonideal electric field, all consistent with a reconnection diffusion region close to the X‐line. In the diffusion region, electrons are modulated by electromagnetic waves. An ion exhaust with energized field‐aligned ions and electron parallel heating are observed in the same shock transition region. The energized ions are more separated from the inflowing ions in velocity above the current sheet than below, possibly due to the shear flow between the two inflow regions. The observation suggests that magnetic reconnection may contribute to shock energy dissipation.
Quartz Flow Law Revisited: The Significance of Pressure Dependence of the Activation Enthalpy
Authors: Lu Lucy X. , Jiang Dazhi 
Published: December 2018

AbstractAn accurate flow law for dislocation creep of quartz aggregates is critical for the understanding of continental rheology, numerical modeling of lithospheric processes, and the interpretation of microstructures of natural quartz‐bearing mylonites. Despite many decades of research, considerable discrepancies still exist among quartz flow laws determined from different experiments. We demonstrate that the key to reconcile these discrepancies is to consider the pressure dependence of the activation enthalpy. From existing high‐quality creep experiments on quartz aggregates, we critically identified test runs having microstructures and stress‐strain curves indicating steady state regimes 2 and 3 dislocation creep and used the data to obtain a set of flow law parameters most consistent among existing experiments. Because estimates of strain rate and stress from natural mylonites are bound with large uncertainties, they cannot be used to construct a flow law better than one determined from well‐controlled creep experiments. A large number of geological studies and modern GPS observations suggest that crustal scale ductile shear zones likely flow at a strain rate range between 10−13 and 10−11 s−1. In this strain rate range, our flow law predicts flow stresses broadly consistent with stress estimates from many natural mylonites based on well‐calibrated piezometers for dynamically recrystallized quartz grains.
Efficient Computation of Green's Functions for Lossy Uniaxial Anisotropic Layered Media
Authors: Li Dawei , Wilton Donald R. , Jackson David R. , Chen Ji , Wang Hanming 
Published: December 2018

AbstractThe efficient computation of Green's functions for uniaxial anisotropic layered media is investigated. Both field and mixed‐potential layered medium Green's functions (LMGFs) are discussed for different applications. An asymptotic subtraction (singularity extraction) and the weighted average method are combined for the acceleration of LMGF computation. A full collection of Sommerfeld and related identities used in the acceleration is summarized and generalized to uniaxial anisotropic medium for both field and mixed‐potential LMGFs. When lossy media are considered, the effective distance from the source to the observation point becomes a complex number depending on the anisotropic ratio of the horizontal to vertical media parameters. In addition, the evaluation of half‐line source potentials, which are introduced to accelerate the scalar potential correction term for vertical currents, is generalized to the complex domain by analytic continuation. Several numerical examples are used to demonstrate the efficiency and accuracy of the resulting algorithms.
Quantitative Evaluation of Nasolabial Alterations following Nasoalveolar Molding (NAM) Therapy in Patients with Unilateral Cleft Lip
Authors: Bui Anthony , Barnett Rebecca , Rousso Joseph , Ahmed Mairaj 
Published: December 2018

AbstractThe clinical benefit of nasoalveolar molding (NAM) is actively debated between cleft centers without clear consensus. Nasolabial measurements were performed on pediatric patients with unilateral clefts of the lip, with or without cleft palate, at an academic cleft/craniofacial center prior to and following NAM therapy between June 2015 and August 2016. The parameters of interest were: columella height and width, cleft nostril height and width, and lip width. Measurements were performed using photographs taken alongside a reference object. The image output was then scaled to the size of the reference object and the capture angle. Intraclass correlation coefficient was calculated to assess reliability of the photographic measurements. Descriptive statistics (mean, standard deviation [SD]) were calculated to characterize the pre- and post-NAM measurements. Student's t-tests were performed to compare the pre-NAM versus post-NAM measurements. The primary objective was to measure the effect of NAM on the nasal aesthetic units that are known to be anatomically aberrant in the cleft lip patient. Nine patients were included in this study. Average pre-NAM age was 2.5 weeks, and average post-NAM age was 13 weeks. Average columellar height increased from 3.70 mm (SD = 0.14) pre-NAM to 5.85 mm (SD = 1.96) post-NAM (p < 0.01); average columellar width increased from 4.71 mm (SD = 0.49) to 5.93 mm (SD = 0.71) (p < 0.01); average cleft nostril height increased from 3.54 mm (SD = 2.97) to 6.81 mm (SD = 2.98) (p = 0.01); and average cleft nostril width decreased from 15.46 mm (SD = 2.91) to 11.05 mm (SD = 1.01) (p = 0.01). Average lip width decreased from 34.61 mm (SD = 1.73) to 33.87 mm (SD = 3.67); however, this change was not statistically significant (p = 0.16). This study objectively quantifies positive changes in nasal aesthetics associated with NAM therapy, providing further evidence for its utility as a presurgical treatment modality for optimal aesthetic nasal results in the unilateral cleft lip patient. The major limitation of this study was a lack of control group, as our center universally treats complete unilateral cleft lip patients with NAM therapy. However, the authors strongly believe that the positive aesthetic nasal findings would persist if compared with a non-NAM control group.
TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives
Authors: Mancarella Serena , Cigliano Antonio , Chieti Annarita , Giannelli Gianluigi , Dituri Francesco 
Published: December 2018

AbstractTherapeutic attempts to treat hepatocellular carcinoma (HCC) frequently result in a poor response or treatment failure. The efficacy of approved drugs and survival expectancies is affected by an ample degree of variability that can be explained at least in part by the enormous between-patient cellular and molecular heterogeneity of this neoplasm. Transforming growth factor-β (TGF-β) is hyperactivated in a large fraction of HCCs, where it influences complex interactive networks covering multiple cell types and a plethora of other local soluble ligands, ultimately establishing several malignancy traits. This cytokine boosts the invasiveness of cancerous epithelial cells through promoting the epithelial-to-mesenchymal transition program, but also skews the phenotype of immune cells toward a tumor-supporting status. Here, we discuss recent strategies pursued to offset TGF-β-dependent processes that promote metastatic progression and immune surveillance escape in solid cancers, including HCC. Moreover, we report findings indicating that TGF-β reduces the expression of the proinflammatory factors CCL4 and interleukin-1β (IL-1β in human ex vivo treated HCC tissues. While this is consistent with the anti-inflammatory properties of TGF-β, whether it is an outright tumor promoter or suppressor is still a matter of some debate. Indeed, IL-1β has also been shown to support angiogenesis and cell invasiveness in some cancers. In addition, we describe an inhibitory effect of TGF-β on the secretion of CCL2 and CXCL1 by HCC-derived fibroblasts, which suggests the existence of an indirect stroma-mediated functional link between TGF-β and downstream immunity.
Geographical Differences in Intracranial Meningioma Management: Examining 65,973 Patients across the United States
Authors: Anzalone Charles Lane , Glasgow Amy , Habermann Elizabeth , Grossard Brandon R. , Van Gompel Jamie J. , Carlson Matthew L. 
Published: December 2018

Background Age, tumor size and location, overall health, and patient preference are primary considerations driving treatment decision-making for intracranial meningiomas. However, even for the same individual patient, treatment recommendations may vary between centers and providers.
Objective To study associations between geography, disease presentation, and management of intracranial meningioma in the United States.
Methods The population-based Surveillance, Epidemiology, and End Results(SEER) data were queried between 2004 and 2014 for cases of intracranial meningioma.
Results A total of 65,808 patients with intracranial meningioma were identified. Univariate analyses demonstrated strong associations between geographic location, age, and size of tumor at presentation. The mean age for all registries was 64.2 years, with a range from 62.0 (Utah registry) to 66.6 (Detroit registry). The greatest proportion of small tumors (<1 cm) were identified in the Utah registry (13.9% of tumors), while the greatest proportion of large tumors (> 4cm) were noted in the Hawaii registry (30.7% of tumors). Multivariable analysis demonstrated that the impact of geography on treatment selection was just as important as other established variables. For example, the distribution in tumor size between New Mexico and Greater California registries is nearly identical; however, the odds ratio for surgery was 1.5 times greater for the New Mexico population.
Conclusion These data suggest that disease presentation and treatment are significantly influenced by regional referral patterns, provider or institutional treatment preferences, and regional availability of subspecialty expertise. Understanding such biases is important for patients, referring physicians, and treatment providers in an effort to provide balanced counseling and treatment.