bluuebunny/crossref_metadata_2025_split huggingface dataset:
External involvement and green product innovation: The moderating role of environmental uncertainty
Authors: Zhao Yunhui , Feng Taiwen , Shi Hongbo 
Published: May 2018

AbstractAlthough the importance of external involvement has been recognized, under what conditions it is more effective is still unclear. To address this research gap, this study explores the moderating roles of three dimensions of environmental uncertainty on the relationship between external involvement and green product innovation based on contingency theory and organizational information processing theory. We examine the research hypotheses employing survey data collected from 198 Chinese manufacturing firms and using hierarchical moderated regression analyses. The results indicate that both customer involvement and supplier involvement have positive effects on green product innovation. Technological uncertainty strengthens the effects of customer involvement and supplier involvement on green product innovation. However, demand uncertainty fails to moderate the relationship between customer involvement and green product innovation, and supply uncertainty fails to moderate the relationship between supplier involvement and green product innovation. This study provides novel and fruitful research avenues for stakeholder involvement and suggests future directions.
How past decisions affect future behavior on eco‐innovation: An empirical study
Authors: Peiró-Signes Ángel , Segarra-Oña Marival 
Published: May 2018

AbstractThe environment is increasingly gaining importance for citizens and society and, therefore, for consumers. Eco‐innovation is a direct path for reducing the impact of production while providing companies with a source of competitive advantage. The automotive industry and its supply chain have a great impact on the environment, but no research has been developed on how the orientation toward the environment is evolving for the automotive industry and how future performance may be affected by current decisions. The aim of this paper is to bridge this gap by analyzing the eco‐innovative dynamism of the automobile industry. To do this, we use a panel analysis to see the point at which past behavior influences future decisions. The partial least square method is used to analyze the eco‐innovative dynamism of the automobile industry. We analyze a data set based on 159 responses of Spanish companies that belong to the automobile sector. Results show that environmental orientation drivers do not evolve over a short period while in the longer term there is an evolution. We prove that carryover effects have a great impact on the future behavior of the firms, showing that the evolution of organizations' environmental behavior is a long‐range consideration. Managerial implications arise from this paper's conclusions, as the decision‐making process is clarified.
Teaching arc‐length continuation in the chemical engineering graduate program using MATLAB©
Authors: Al‐Mubaiyedh Usamah A. , Binous Housam 
Published: May 2018

AbstractWe present the solution of six problems drawn from the chemical engineering and applied mathematics fields of study. These problems are solved using the arc‐length continuation method. Among a large number of examples, we have chosen to treat the following case studies because they illustrate basic concepts such as solution multiplicity when dealing with systems of nonlinear algebraic equations or boundary value problems: 1) Plotting an ∞‐shaped curve called the Bernoulli's Lemniscate; 2) Computing the Joule‐Thomson inversion curve for a pure gas using the Soave‐Redlich‐Kwong cubic equation of state; 3) Predicting the Compressibility Factor and Molar Volume versus the Reduced Temperature; 4) Determining region where steady‐state multiplicity is observed in a continuous stirred‐tank reactor (CSTR) with multiple reactions and heat effects; 5) Finding the steady‐state temperature and conversion of a Propylene Glycol Reactor; and 6) Investigating the Frank–Kamenetskii problem arising in the self‐heating of a reactive solid. Reader should be advised that problem 1 may seem slightly mathematical in nature. However, case studies 2–6 could be very useful to instructors involved in teaching not only numerical methods but also chemical thermodynamics and chemical reaction engineering. For one of the above listed case studies, we unveil the MATLAB© code, that we have employed, in the Appendix. In addition, we will emphasize on the versatility of this mathematical software through the extensive usage of the built‐in command fsolve, for the presently undertaken computations. Finally, we conclude this paper by sharing our experience teaching this subject to graduate students at King Fahd University of Petroleum & Minerals.
The role of shared social identity in mutual support among refugees of conflict: An ethnographic study of Syrian refugees in Jordan
Authors: Alfadhli Khalifah , Drury John 
Published: May 2018

AbstractIn the midst of an unprecedented refugee crisis and the shortfall of aid organization resources, a shift toward utilizing the capacity for collective resilience in refugee communities could be helpful. This paper explores experiences of psychosocial social support among a community of Syrian urban refugees in Jordan, especially the kind of support that helps them deal with secondary stressors. We were specifically interested in the role of shared social identity as a basis of support and the sources of such shared identity. We conducted an 8‐month ethnography that included observations and semistructured interviews with 13 refugees. We found many examples of support among refugees, on both personal and collective levels. Some of this support was based on sharing the identity of “refugee” that stemmed from a sense of common fate. This is similar to the process identified in the literature on disasters. Psychological membership in the refugee group is stigmatic, but it can also lead to positive outcomes in line with the social cure perspective. However, we also found examples of support that were value‐based or based on pre‐existing interpersonal networks. Implications of the findings for models of group processes in stressful situations and the practical question of refugee support are discussed.
Insights from Computations on the Mechanism of Reduction by Ascorbic Acid of PtIV Prodrugs with Asplatin and Its Chlorido and Bromido Analogues as Model Systems
Authors: Ponte Fortuna , Russo Nino , Sicilia Emilia 
Published: May 2018

AbstractThe elucidation of the mechanism by which the reduction of coordinatively saturated PtIV prodrugs occurs, leading to the release of the two axial ligands, is of foremost importance, being the key step for the activation of these anticancer compounds, and addressing their synthetic strategies. A systematic DFT computational analysis of the reduction process by small biomolecules, which is supposed to occur by inner‐ or outer‐sphere electron‐transfer mechanisms, has been undertaken using the recently synthesised Asplatin PtIV complex, c,c,t‐[PtCl2(NH3)2(OH)(aspirin)], as model system and l‐ascorbic acid as reducing agent. Further calculations have been carried out on Asplatin analogues that should be obtained replacing the OH− ligand with Cl− and Br−. The most accredited inner‐sphere mechanistic suggestions have been explored and a recently proposed computational methodology has been applied to estimate the corresponding standard redox potentials, which cannot be directly obtained from voltammetric experiments due to the irreversibility of the platinum(IV)‐to‐platinum(II) reduction process.
Multiple Hydrogen‐Bond Activation in Asymmetric Brønsted Acid Catalysis
Authors: Liao Hsuan‐Hung , Hsiao Chien‐Chi , Atodiresei Iuliana , Rueping Magnus 
Published: May 2018

AbstractAn efficient protocol for the asymmetric synthesis of chiral tetrahydroquinolines bearing multiple stereogenic centers by means of asymmetric Brønsted acid catalysis was developed. A chiral 1,1′‐spirobiindane‐7,7′‐diol (SPINOL)‐based N‐triflylphosphoramide (NTPA) proved to be an effective Brønsted acid catalyst for the in situ generation of aza‐ortho‐quinone methides (aza‐o‐QMs) and their subsequent cycloaddition reaction with unactivated alkenes to provide the products with excellent diastereo‐ and enantioselectivities. In addition, DFT calculations provided insight into the activation mode and nature of the interactions between the N‐triflylphosphoramide catalyst and the generated aza‐o‐QMs.
Assembly of ZIF‐67 Metal–Organic Framework over Tin Oxide Nanoparticles for Synergistic Chemiresistive CO2 Gas Sensing
Authors: DMello Marilyn Esclance , Sundaram Nalini G. , Kalidindi Suresh Babu 
Published: May 2018

AbstractMetal–organic frameworks (MOFs) are widely known for their record storage capacities of small gas molecules (H2, CO2, and CH4). Assembly of such porous materials onto well‐known chemiresistive gas sensing elements such as SnO2 could be an attractive prospect to achieve novel sensing properties as this affects the surface chemistry of SnO2. Cobalt‐imidazole based ZIF‐67 MOF was grown onto preformed SnO2 nanoparticles to realize core–shell like architecture and explored for greenhouse gas CO2 sensing. CO2 sensing over SnO2 is a challenge because its interaction with SnO2 surface is minimal. The ZIF‐67 coating over SnO2 improved the response of SnO2 up to 12‐fold (for 50 % CO2). The SnO2@ZIF‐67 also showed a response of 16.5±2.1 % for 5000 ppm CO2 (threshold limit value (TLV)) at 205 °C, one of the best values reported for a SnO2‐based sensor. The observed novel CO2 sensing characteristics are assigned to electronic structure changes at the interface of ZIF‐67 and SnO2.
Pentafluoroethylated Compounds of Silicon, Germanium and Tin
Authors: Wiesemann Markus , Hoge Berthold 
Published: May 2018

AbstractIn this contribution we present an account on pentafluoroethylated compounds of silicon, germanium and tin. The pronounced electron‐withdrawing effect of the pentafluoroethyl group leads to a markedly increased Lewis acidity at the central atom which results in the stabilization of hypervalent complexes, anionic element(II) species as well as remarkable reactivities of element‐element and element‐hydrogen bonds. By addition to unsaturated C−C bonds or by reaction with organic halides as well as transition‐metal complexes the molecules bearing a pentafluoroethyl‐element group are readily accessible. Moreover, the utilization of pentafluoroethyl groups facilitates the formation of donor‐stabilized germylenes and stannylenes. A series of such compounds serves as suitable pentafluoroethylation reagents. Conversely to the well‐studied trifluoromethyl derivatives these compounds frequently exhibit a higher thermostability, which allows a more convenient handling.
A Magnetic Chameleon: Biocompatible Lanthanide Fluoride Nanoparticles with Magnetic Field Dependent Tunable Contrast Properties as a Versatile Contrast Agent for Low to Ultrahigh Field MRI and Optical Imaging in Biological Window
Authors: Biju Silvanose , Gallo Juan , Bañobre‐López M. , Manshian Bella B. , Soenen Stefaan J. , Himmelreich Uwe , Vander Elst Luce , Parac‐Vogt Tatjana N. 
Published: May 2018

AbstractInvited for the cover of this issue is the group of Tatjana N. Parac‐Vogt at the University of KU Leuven. The image depicts the chameleonic nature of the nanoparticle contrast agent, in response to external stimuli. Read the full text of the article at 10.1002/chem.201800283.
Non‐Covalent Interactions of a Neuroprotective Peptide Revealed by Photodissociative Cross‐Linking in the Gas Phase
Authors: Liu Yang , Ramey Zachary , Tureček František 
Published: May 2018

AbstractThe small neuroprotective peptide Cys‐Ala‐Gln‐Lys (CAQK) was selectively tagged with a diazirine group and its photochemical cross‐linking was studied with model target peptides. Experimental results in combination with Born–Oppenheimer molecular dynamics revealed the structural preferences for binding to the amino acid residues in the target peptides. Effects of the target peptide sequence and N‐ and C‐terminal modifications are discussed.
Intercepting a Transient Phosphino‐Arsinidene
Authors: Hinz Alexander , Hansmann Max M. , Bertrand Guy , Goicoechea Jose M. 
Published: May 2018

AbstractA phosphino‐arsinidene derived from a diazaphospholidine scaffold (Ar**NCH2)2PAs (where Ar**=2,6‐bis[(4‐tert‐butylphenyl)methyl]‐4‐methylphenyl) was generated in situ and trapped with a range of reagents. Metathesis reactions between (Ar**NCH2)2PCl and either [Na(18‐crown‐6)][AsCO] or [Na(dioxane)x][AsCO] are believed to afford an arsaketene, (Ar**NCH2)2PAsCO, which readily loses carbon monoxide under ambient conditions. The resulting transient arsinidene was shown to undergo cycloaddition reactions with excess AsCO−, but can be stabilised in the presence of Lewis bases. It displays contrasting reactivity from a previously reported phosphino‐phosphinidene. With isonitriles, rearrangements occur, however with PPh3 a phosphine‐stabilised arsinidene could be isolated and used for subsequent reactivity studies. This species was found to be a suitable starting material for a transition metal complex of the phosphino‐arsinidene, in which the P−As moiety coordinates side‐on to the metal centre.
Early results of lower dose dasatinib (50 mg daily) as frontline therapy for newly diagnosed chronic‐phase chronic myeloid leukemia
Authors: Naqvi Kiran , Jabbour Elias , Skinner Jeffrey , Yilmaz Musa , Ferrajoli Alessandra , Bose Prithviraj , Thompson Philip , Alvarado Yesid , Jain Nitin , Takahashi Koichi , Burger Jan , Estrov Zeev , Borthakur Gautam , Pemmaraju Naveen , Paul Shilpa , Cortes Jorge , Kantarjian Hagop M. 
Published: May 2018

BACKGROUNDDasatinib is a potent BCR‐ABL1 and Src family tyrosine kinase inhibitor. It is approved at a dose of 100 mg orally daily for the treatment of chronic myeloid leukemia in chronic phase (CML‐CP). This dose schedule is associated with myelosuppression and pleural effusions. Anecdotal data suggest that lower doses may be as effective and less toxic. The aim of this study was to assess the efficacy and safety of a lower dose of dasatinib (50 mg daily) in patients with newly diagnosed CML‐CP.METHODSSeventy‐five patients with newly diagnosed CML‐CP received dasatinib 50 mg daily. The eligibility and response criteria were standards used in previous protocols.RESULTSAt a median follow‐up of 9 months, 60 patients were evaluable for a response at 3 months. The rates of patients achieving BCR‐ABL1 transcript levels ≤ 10% and ≤ 1% at 3 months by the International Standard were 93% and 72%, respectively. The rates of complete cytogenetic response by conventional cytogenetics or fluorescence in situ hybridization at 6 and 12 months were 86% and 88%, respectively. At 12 months, 79%, 71%, and 46% of the patients had achieved a major molecular response, a molecular response with a 4.0‐log reduction, and a molecular response with a 4.5‐log reduction, respectively. Nine patients had a dose interruption for ≤14 days. Only 1 patient developed a pleural effusion requiring a dose reduction to 20 mg. All patients remained alive and with no transformation so far.CONCLUSIONDasatinib 50 mg daily is active and well tolerated in patients with newly diagnosed CML‐CP. It should be further explored as a new potential standard‐of‐care option for chronic myeloid leukemia. Cancer 2018;124:2740‐2747. © 2018 American Cancer Society
Phase 2 trial of bortezomib in combination with rituximab plus hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone alternating with bortezomib, rituximab, methotrexate, and cytarabine for untreated mantle cell lymphoma
Authors: Romaguera Jorge E. , Wang Michael , Feng Lei , Fayad Luis E. , Hagemeister Frederick , McLaughlin Peter , Rodriguez M. Alma , Fanale Michelle , Orlowski Robert , Kwak Larry W. , Neelapu Sattva , Oki Yasuhiro , Pro Barbara , Younes Anas , Samaniego Felipe , Fowler Nathan , Hartig Kimberly , Valentinetti Marisa , Smith Judy , Ford Peggy , Naig Adam , Medeiros L. Jeffrey , Kantarjian Hagop M. , Goy Andre 
Published: May 2018

BACKGROUNDAlthough the outcomes of patients with mantle cell lymphoma (MCL) have improved, there is still no cure. Bortezomib has a 33% response rate in relapsed/refractory MCL and has shown additive and/or synergistic effects in preclinical trials with known effective agents.METHODSThis is a report of a prospective phase 2 trial of bortezomib added to rituximab plus hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone (BzR‐hyperCVAD)/rituximab, high‐dose methotrexate, and high‐dose cytarabine (BzR‐MA) for 95 patients with newly diagnosed MCL.RESULTSThe overall and complete response rates were 100% and 82%, respectively. Hematologic toxicity was high but expected and did not lead to an increased incidence of neutropenic fever or dose reductions in comparison with a similar reported regimen without bortezomib. After a median follow‐up of 44 months, the median overall survival had not been reached, and the time to treatment failure (TTF) was 55 months, which is not different from that of historical controls.CONCLUSIONSBzR‐hyperCVAD/BzR‐MA at the dose and schedule studied produced high rates of response and a TTF similar to that of historical reports without bortezomib. Cancer 2018;124:2561‐9. © 2018 American Cancer Society.
Heuristic analysis influence of saliency in the color diversity of natural images
Authors: Nieves Juan Luis , Romero Javier 
Published: May 2018

AbstractThe estimation of chromatic diversity of natural images is commonly quantified through the computation of the number of discernible colors and has received much attention because of the different implications it has. However, the relationship between that number and the number of colors that really attracts the attention from an observer is still not clear and has been given little attention. New concepts about salient discernible colors‐the salient chromatic diversity of images‐ and remarkable salient colors‐connected colors in the same salient image area‐are introduced as opposed to the classical number of discernible object colors, which is usually evaluated for the global image without differentiating between probable attended and non‐attended image regions. We have used different well‐known saliency models to locate the salient regions in the scenes and have heuristically studied the extent to which those models preserve the chromatic diversity of natural images. Based on a bottom‐up approach, a reduction of around 40%‐55% in the number of discernible colors were obtained, and not all saliency algorithms preserved a uniform sampling of the original color gamut. Thus, our results suggests that particularly the graph‐based visual saliency model got good low dissimilarity values in comparison with other approaches that put emphasis solely on color as the main low‐level feature. Furthermore, we have introduced a quantification scheme of the average number of remarkable salient colors appearing in the images, and have proved how the heuristic‐based analysis of salient image areas can be used to create segmented images automatically according to their salient chromatic diversity.
Papanicolaou induced fluorescence, Ziehl‐Neelsen and Auramine O stains on lymph node fine needle aspiration biopsy specimens from children: A comparative study
Authors: Selepe Malesiba Mampotoko , van Wyk Abraham Christoffel , Hoek Kim Gilberte Pauline , Prince Yvonne , van Helden Paul David , Warren Robin Mark , Wright Colleen Anne 
Published: May 2018

BackgroundThe rapid diagnosis of extrapulmonary tuberculosis in children remains challenging. The presence of enlarged lymph nodes provides an opportunity to obtain diagnostic material through fine needle aspiration biopsy (FNAB). Mycobacterial culture, traditionally the reference standard, has a slow turnaround time and PCR‐based methods are not widely available in developing countries. Direct visualization of mycobacteria on microscopy can be a rapid method to confirm the diagnosis. This study compared three staining methods to visualize mycobacteria.MethodsHundred FNAB specimens from persistently enlarged lymph nodes in children, clinically suspicious for tuberculosis, were evaluated for the presence of mycobacteria by three staining methods: Papanicolaou induced fluorescence (PIF) and Auramine O staining using fluorescence microscopy and Ziehl‐Neelsen (ZN) staining using conventional light microscopy. These methods were evaluated against mycobacterial culture.ResultsPIF positivity was 30%, with 38% and 48% for Auramine O and ZN respectively. The combined ZN/PIF positivity was 56%. The highest diagnostic accuracy (73%) was demonstrated by ZN alone and in combination with PIF, with PIF alone showing the lowest (49%) accuracy. Although the combined test showed the highest sensitivity, it had the lowest specificity, while ZN was significantly more sensitive than both other staining modalities. No statistical difference in specificity was seen among the tests.ConclusionThis study suggests that Auramine O staining on previously ZN stained slides does not significantly improve diagnostic accuracy. While currently widely available methods of direct visualization of mycobacteria suffer from low sensitivity, the ZN stain remains a useful diagnostic test, particularly in resource‐constrained countries.
Reserve design to optimize the long‐term persistence of multiple species
Authors: Strimas‐Mackey Matthew , Brodie Jedediah F. 
Published: May 2018

AbstractProtected areas form the cornerstone of global efforts to conserve biodiversity. Most current methods for designing reserve networks focus on maximizing the representation of species, but with no assurance that those species will persist in the protected landscapes into the future. We present a new strategy for reserve design that combines metapopulation theory with spatial conservation prioritization to estimate conservation solutions that minimize extinction risk across numerous species simultaneously. Our framework optimizes the spatial configuration of reserves to maximize metapopulation persistence for an entire assemblage of species by accounting for both species representation and landscape connectivity. As a case study, we design a reserve network for 114 terrestrial mammal species in Indonesian New Guinea. Our approach builds on Marxan, the flagship representation‐based reserve design tool, improving estimated persistence (metapopulation capacity) by an average of 4.6‐fold across species, without increasing the socioeconomic cost. We suggest that enhancing species persistence, rather than protecting arbitrary proportions of species’ ranges, should be the ultimate objective of conservation planning.
Loyal peripherals? The interactive effects of identification and peripheral group membership on deviance from non‐beneficial ingroup norms
Authors: Masson Torsten , Fritsche Immo 
Published: May 2018

AbstractFor ensuring the well‐being of groups, people are needed who deviate from ingroup norms that harm the group (“loyal deviance”). Qualifying previous results that loyal deviants have to be highly identified with the group, we hypothesize and show that this is only true when group members at the same time feel that they are highly prototypical for the group. No such effects occurred for peripheral members. In all three studies (N1 = 207, N2 = 115, N3 = 107), we measured people's intention to conform to a non‐beneficial (vs. beneficial; Study 1) ingroup norm, self‐investment in the group, and perceived (manipulated in Study 3) marginalization. Obviously, dissent from non‐beneficial norms requires both a deep psychological investment in the group as well as secure ingroup membership. Implications are discussed.