bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pneumoniaversusgraft dysfunction as the cause of acute respiratory failure after lung transplant: a 4-year multicentre prospective study in 153 adults requiring intensive care admission
Authors: Mazo Cristopher , Pont Teresa , Ballesteros Maria A. , López Eloísa , Rellán Luzdivina , Robles Juan C. , Rello Jordi 
Published: July 2019

We aimed to assess the main causes of intensive care unit (ICU) readmissions in lung transplant adults and to identify independent predictors of ICU mortality (primary end-point).This Spanish five-centre prospective cohort study enrolled all lung transplant adults with ICU readmissions after post-transplant ICU discharge between 2012 and 2016. Patients were followed until hospital discharge or death.153 lung transplant recipients presented 174 ICU readmissions at a median (interquartile range) of 6 (2–25) months post-transplant. Chronic lung allograft dysfunction was reported in 39 (25.5%) recipients, 13 of whom (all exitus) had restrictive allograft syndrome (RAS). Acute respiratory failure (ARF) (110 (71.9%)) was the main condition requiring ICU readmission. Graft rejection (six (5.4%) acute) caused only 12 (10.8%) readmissions whereas pneumonia (56 (36.6%)) was the main cause (50 admitted for ARF and six for shock), withPseudomonas aeruginosa(50% multidrug resistant) being the predominant pathogen. 55 (35.9%) and 69 (45.1%) recipients died in the ICU and the hospital, respectively. Bronchiolitis obliterans syndrome (BOS) stage 2 (adjusted OR (aOR) 7.2 (95% CI 1.0–65.7)), BOS stage 3 (aOR 13.7 (95% CI 2.5–95.3)), RAS (aOR >50) and pneumonia at ICU readmission (aOR 2.5 (95% CI 1.0–7.1)) were identified in multivariate analyses as independent predictors of ICU mortality. Only eight (5.2%) patients had positive donor-specific antibodies prior to ICU readmission and this variable did not affect the model.ARF was the main condition requiring ICU readmission in lung transplant recipients and was associated with high mortality. Pneumonia was the main cause of death and was also an independent predictor. RAS should receive palliative care rather than ICU admission.
An Abstract Linking Theorem Applied to Indefinite Problems Via Spectral Properties
Authors: Maia Liliane A. , Soares Mayra 
Published: July 2019

Abstract
An abstract linking result for Cerami sequences is proved without the Cerami condition. It is applied directly in order to prove the existence of critical points for a class of indefinite problems in infinite-dimensional Hilbert Spaces. The applications are given to Schrödinger equations. Here spectral properties inherited by the potential features are exploited in order to establish a linking structure, and hence hypotheses of monotonicity on the nonlinearities are discarded.
Comparative analysis of gut microbiota among the male, female and pregnant giant pandas (Ailuropoda Melanoleuca)
Authors: Zhao Siyue , Li Caiwu , Li Guo , Yang Shengzhi , Zhou Yingming , He Yongguo , Wu Daifu , Zhou Yu , Zeng Wen , Li Ti , Qu Yuanyuan , Li Bei , Deng Wenwen , Jin Lei , Yu Xiumei , Huang Yan , Zhang Hemin , Zou Likou 
Published: July 2019

AbstractThe giant panda (GP) was the most endangered species in China, and gut microbiota plays a vital role in host health. To determine the differences of the gut microbiota among the male, female and pregnant GPs, a comparative analysis of gut microbiota in GPs was carried out by 16S rRNA and ITS high-throughput sequencing. In 16S rRNA sequencing, 435 OTUs, 17 phyla and 182 genera were totally detected. Firmicutes (53.6%) was the predominant phylum followed by Proteobacteria (37.8%) and Fusobacteria (7.1%). Escherichia/Shigella (35.9%) was the most prevalent genus followed by Streptococcus (25.9%) and Clostridium (11.1%). In ITS sequencing, 920 OTUs, 6 phyla and 322 genera were also detected. Ascomycota (71.3%) was the predominant phylum followed by Basidiomycota (28.4%) and Zygomycota (0.15%). Purpureocillium (4.4%) was the most prevalent genus followed by Cladosporium (2.5%) and Pezicula (2.4%). Comparative analysis indicated that the male GPs harbor a higher abundance of phylum Firmicutes than female GPs with the contribution from genus Streptococcus. Meanwhile, the female GPs harbor a higher abundance of phylum Proteobacteria than male GPs with the contribution from genus Escherichia/ Shigella. In addition, the shift in bacteria from female to pregnant GPs indicated that phylum Firmicutes increased significantly with the contribution from Clostridium in the gut, which may provide an opportunity to study possible associations with low reproduction of the GPs.
Early pregnancy reference intervals; 29 serum analytes from 4 to 12 weeks’ gestation in naturally conceived and uncomplicated pregnancies resulting in live births
Authors: Friis Petersen Jesper , Friis-Hansen Lennart J. , Jensen Andreas Kryger , Nyboe Andersen Anders , Løkkegaard Ellen C.L. 
Published: July 2019

Abstract

Background
Pregnancy introduces major physiological changes that also alter biochemical analytes. Maternal and perinatal health can be optimized by early intervention and therefore, pregnancy-specific reference intervals (RIs) for the local population are warranted. While the second and third trimester-specific changes are well described, the first trimester is less well characterized. We therefore wanted to facilitate early detection of abnormalities by generating first trimester reference values for 29 common analytes.

Methods
In a prospective early pregnancy (PEP) cohort (2016–2017), 203 pregnant women were recruited from 4 to 8 weeks’ gestation. Consecutive blood samples were drawn every 2 weeks until an ongoing second trimester pregnancy (n = 164) or a miscarriage (n = 39) occurred. After exclusion of women with complicated pregnancies or deliveries (n = 42), 122 women were included. The serum samples collected at <6, 6–8, 8–10, 10–12 and >12 weeks’ gestation were analyzed for 29 common analytes. Subsequently the RIs were calculated according to the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) recommendations (2.5–97.5th percentiles) and compared with the conventional RIs for non-pregnant women.

Results
Human chorionic gonadotropin (hCG), progesterone (P4), estradiol (E2), pregnancy-associated plasma protein A (PAPP-A), cancer antigen 125 (CA125), thyroid stimulating hormone (TSH), creatinine (CREA) and albumin (ALB) showed an early pregnancy-dependent change compared with conventional limits. For ALB the change was seen at 5.5 weeks’ gestation.

Conclusions
We report gestational age-specific RIs available from the early part of the first trimester applicable to everyday clinical care of pregnant women. Well-known alterations of RIs seen in later trimesters are also observed in the first.
Rubber toughened flame retardant (FR) polyamide 11 nanocomposites Part 2: synergy between multi-walled carbon nanotube (MWNT) and MMT nanoclay
Authors: Wu Hao , Ortiz Rogelio , Koo Joseph H. 
Published: July 2019

AbstractIn the previous study, flame retardant (FR) polyamide 11 (PA11) nanocomposites formulations designed for selective laser sintering (SLS)were prepared and characterized. The SEBS-g-MA elastomer successfully improved the material’s ductility. Although the nonhalogenated FR additives and montmorillonite (MMT) nanoclay successfully decreased the heat release capacity (HRC) and peak heat release rate (pHRR) as characterized by microscale combustion calorimeter (MCC). None of the rubber toughened formulations achieved UL 94 V0 rating, which is a bench mark for many FR polymer applications. As part two of this study, we explored the synergism between two nanoparticles, nanoclay and multi-walled carbon nanotubes (MWNTs), to see whether better FR properties can be achieved. TEM micrographs indicate that both nanoclay and MWNTs achieved high level of dispersion. Flammability results showed that all formulations achieved UL 94 V0 rating, which is a significant improvement from the previous formulations without MWNTs. Char morphology characterization indicated that a solid carbonaceous char layer was reinforced by nanoclay and MWNTs.
Improvement of the photoinduced birefringence in azopolymer PAZO doped with TiO2 nanoparticles via thermal treatment
Authors: Mateev Georgi , Nedelchev Lian , Georgiev Anton , Nazarova Dimana 
Published: July 2019

Abstract
We present a study of the photoinduced birefringence in nanocomposite films of the azopolymer PAZO (poly[1-[4-(3-carboxy-4-hydroxyphenylazo)benzenesulfon amido]-1,2-ethanediyl, sodium salt]) doped with TiO2 nanoparticles (NP) with different concentrations before and after thermal annealing. The NP represent nanopowder with primary particle size 21 nm. The concentration of the NP was varied from 0% (non-doped azopolymer film) to 5 wt%. The thermal process, applied to the nanocomposite films, includes 1 h heating at 200°C. Previous studies of PAZO show that the polymer is stable up to 270°C. We study the dependence of the maximal birefringence induced with He-Cd laser (λ= 442 nm) on the concentration of the TiO2 NP in the azopolymer thin films as well as thermal effect on the absorbance spectra of the thin films. As indicated by our results, the birefringence is higher for the thermally annealed samples. An increase of the photoinduced birefringence is also observed for the nanocomposite layers with 1% NP for the non-annealed films, and with 2% NP for the annealed films.
Low Field NMR Studies of Wheat Bread Enriched with Potato Juice During Staling
Authors: Kowalczewski Przemysław Łukasz , Walkowiak Katarzyna , Masewicz Łukasz , Baranowska Hanna Maria 
Published: July 2019

Abstract
Potato juice is a by-product in the production of starch from potato tubers. However, published studies indicate that it is a source of bioactive compounds with antioxidant and anti-inflammatory effects. The use of health-promoting additives may, however, affect the quality of the fresh final product as well as the stored one. Water behavior is one of the parameters whose analysis allows for the monitoring of the shelf life of products. Therefore, the research reported in this paper was aimed at investigating the effect of replacing wheat flour with spray-dried potato juice (SDPJ) at 2.5%, 5% and 7.5% on water behavior during bread staling. 1H Nuclear Magnetic Resonance (NMR) was used to analyze the impact of SDPJ on the dynamics of water in bread crumb. The NMR analyzes revealed that 7.5% addition of SDPJ resulted in an increased ratio of bound to bulk water (decreased T1 spin-lattice time) and decreased mobility of bulk water (decreased T22 spin-spin time). The enriched breads also showed different dynamics of water during storage, however, in each of the analyzed variants a slight increase in T1 was noted. It has also been shown that enrichment of bread in SDPJ accelerates the evacuation of water from the polymer network.
Computational simulation of mechanism and isotope effects on acetal heterolysis as a model for glycoside hydrolysis
Authors: Glancy John H. , Lee Daniel M. , Read Emily O. , Williams Ian H. 
Published: July 2019

Abstract
DFT calculations for the equilibrium isotope effect for deuterium substitution at the anomeric centre Cα in 2-(p-nitrophenoxy)tetrahydropyran with continuum solvation show significant variation in the range of relative permittivity 2 ≤ ε ≤ 10. One-dimensional scans of potential energy (with implicit solvation by water) or of free energy (from QM/MM potentials of mean force with explicit aqueous solvation with a hybrid AM1/OPLS method) for heterolysis of the bond between Cα and the nucleofuge do not show a transition state. A two-dimensional free-energy surface that considers also the distance between Cα and a nucleophilic water indicates a pre-association DN*ANint
‡ mechanism with a transition state involving nucleophilic attack upon an ion-pair intermediate, and this is supported by good agreement between the mean values of the calculated and experimental α-D KIEs. However, the magnitudes of the standard deviations about the mean values for the making and breaking C–O bonds suggest that the transition state is rather plastic, with Cα–Onu≈2 ± 0.4 Å and Cα–Olg≈3 ± 0.5 Å. Not only is nucleophilic solvent assistance necessary, but there is also evidence for electrophilic assistance through specific hydrogen bonding to the nucleofuge.
Magnetized fluidized bed with binary admixture of magnetizable and nonmagnetizable particles
Authors: Zhu Quanhong , Li Hongzhong , Huang Qingshan 
Published: July 2019

Abstract
Magnetic fields were used to successfully improve the fluidization quality of magnetizable particles, forming the magnetized fluidized bed (MFB). Moreover, researchers found that the binary admixture of magnetizable and nonmagnetizable particles could also be used in the MFB, creating the admixture MFB. Consequently, the MFB technique is no longer restricted to the few magnetizable particles in nature and can be extended to numerous nonmagnetizable particles. Nevertheless, research on the admixture of MFB is far from sufficient, severely hindering its commercial application in the chemical and biochemical industries. To deepen our understanding in this area, this review summarizes the relevant findings, which mainly include (1) transport phenomena in the gas-solid admixture MFB with Geldart B particles; (2) elimination of the abnormal fluidization phenomena in the gas-solid admixture MFB with Geldart C particles; (3) flow regime transition of the liquid-solid admixture MFB under both the magnetization-FIRST and magnetization-LAST operation modes; and (4) application of the pure MFB in the fields of gas filtration and coal dry separation. Finally, critical comments are made on the shortcomings of the reported research with the hope that more efforts could be devoted to these aspects in the future.
Uncertainty and Forecasts of U.S. Recessions
Authors: Pierdzioch Christian , Gupta Rangan 
Published: July 2019

Abstract
We estimate Boosted Regression Trees (BRT) on a sample of monthly data that extends back to 1889 to recover the predictive value of disaggregated news-based uncertainty indexes for U.S recessions. We control for widely-studied standard predictors and use out-of-sample metrics to assess forecast performance. We find that war-related uncertainty is among the top five predictors of recessions at three different forecast horizons (3, 6, and 12 months). The predictive value of war-related uncertainty has fallen in the second half of the 20th century. Uncertainty regarding the state of securities markets has gained in relative importance. The probability of a recession is a nonlinear function of war-related and securities-markets uncertainty. Receiver-operating-characteristic curves show that uncertainty improves out-of-sample forecast performance at the longer forecast horizons. A dynamic version of the BRT approach sheds light on the importance of various lags of government-related uncertainty for recession forecasting at the long forecast horizon.
Die Bedeutung von in bonis in der actio Serviana
Authors: Sirks Boudewijn 
Published: July 2019

Abstract

The meaning of in bonis in the actio Serviana. The dominant view in the literature on the Serviana (and Publiciana) regarding the meaning of the expression in bonis in the formula is that it refers to quiritary ownership or to possession which leads by way of usucapion to quiritary ownership (the so called bonitary ownership). Yet this view does not consider the fact that provincial land, of which there could only be a protected possession, could be pledged and seized by the pledgee with an action called the quasi Serviana or hypothecaria. Apparently this action applied to bona fide possession ex iusta causa, yet here also we find the expression in bonis for such possession. The conclusion is that in any case in the Serviana in bonis included also such bona fide possession which did not lead through usucapion to quiritary ownership.
Saturnina verkauft ihre Kinder
Authors: Isola Lisa 
Published: July 2019

Abstract

Saturnina sells her children. There is only one source on the sale of one's own freeborn children from classical times: a rescript of Caracalla in C. 7,16,1. Given the fact that the inquiry was most probably made by a woman – Saturnina –, it is unlikely that one can use this text for a study of the paternal ius vendendi in Roman law, as it has happened in the past. The following article will focus on the textual tradition, especially of the inscriptio, but will develop arguments regarding the content of this text as well.
„Urbanes” Mietrecht? Der römische Wohnungsmarkt zwischen Preismechanismus und Intervention
Authors: Willems Constantin 
Published: July 2019

Abstract

'Urban' tenancy law? The Roman rental market between price mechanism and intervention. Renting a flat in Roman times did not come cheap. The Roman jurists left the determination of the merces up to the parties to the locatio conductio and permitted them to circumvent each other in the course of the contract negotiations (se invicem circumscribere) – a rule that at first glance seems to privilege the landlord. In this paper, it is suggested that the system of sub-rent of insulae and the standardized Roman rental year, starting each year at the calends of July, contributed to a reduction in asymmetry of bargaining power between landlord and tenant. Only in exceptional cases there were external interventions in the price mechanism: In the perils of the civil war, Julius Caesar and Octavian issued laws remitting the annual rent below 500 sesterces for the inhabitants of Italy and below 2,000 sesterces for those of the city of Rome. In conclusion, these structures and rules show that in this regard, Roman tenancy law was specifically designed with a view to the inhabitants of the city of Rome and thus can be qualified as 'urban' law.
Subjektive Qualität ambulanter Pflege – Bewertungsrelevante Aspekte aus Sicht von Pflegebedürftigen und Pflegepersonen
Authors: Niens Christine , Hille Cornelius , Marggraf Rainer 
Published: July 2019

AbstractIn diesem Beitrag wird untersucht, welche Aspekte die Grundlage für die Bewertung der Qualität ambulanter Pflege aus Sicht von Pflegebedürftigen und Pflegepersonen bilden. Bislang wurde dies in der aktuellen Pflegeforschung und in Befragungen zur pflegerischen Versorgung vernachlässigt. Auf Grundlage von qualitativen Interviews mit Pflegebedürftigen und deren Pflegepersonen konnten verschiedene Kriterien herausgearbeitet werden, die für die subjektive Bewertung der Pflegequalität maßgeblich sind. Darauf aufbauend wird vorgeschlagen, diese Kriterien in zukünftige Untersuchungen oder Befragungen zur Qualität der ambulanten pflegerischen Versorgung zu integrieren.
Using Quality Improvement to Implement a Standardized Approach to Neonatal Herpes Simplex Virus
Authors: Brower Laura H. , Wilson Paria M. , Murtagh Kurowski Eileen , Haslam David , Courter Joshua , Goyal Neera , Durling Michelle , Shah Samir S. , Schondelmeyer Amanda 
Published: July 2019

OBJECTIVES:
Neonatal herpes simplex virus (HSV) infections are associated with high mortality and long-term morbidity. However, incidence is low and acyclovir, the treatment of choice, carries risk of toxicity. We aimed to increase the percentage of patients 0 to 60 days of age who are tested and treated for HSV in accordance with local guideline recommendations from 40% to 80%.

METHODS:
This quality improvement project took place at 1 freestanding children’s hospital. Multiple plan-do-study-act cycles were focused on interventions aimed at key drivers including provider buy-in, guideline availability, and accurate identification of high-risk patients. A run chart was used to track the effect of interventions on the percentage managed per guideline recommendations over time by using established rules for determining special cause. Pre- and postimplementation acyclovir use was compared by using a χ2 test. In HSV-positive cases, delayed acyclovir initiation, defined as &gt;1 day from presentation, was tracked as a balancing measure.

RESULTS:
The median percentage of patients managed according to guideline recommendations increased from 40% to 80% within 8 months. Acyclovir use decreased from 26% to 7.9% (P &lt; .001) in non–high-risk patients but did not change significantly in high-risk patients (73%–83%; P = .15). There were no cases of delayed acyclovir initiation in HSV-positive cases.

CONCLUSIONS:
Point-of-care availability of an evidence-based guideline and interventions targeted at provider engagement improved adherence to a new guideline for neonatal HSV management and decreased acyclovir use in non–high-risk infants. Further study is necessary to confirm the safety of these recommendations in other settings.
Serious Bacterial Infections in Neonates Presenting Afebrile With History of Fever
Authors: Ramgopal Sriram , Walker Lorne W. , Tavarez Melissa M. , Nowalk Andrew J. , Vitale Melissa A. 
Published: July 2019

BACKGROUND:Infants ≤28 days of age with fever are frequently hospitalized while undergoing infectious evaluation. We assessed differences in rates of serious bacterial infection (SBI; bacteremia, bacterial meningitis, urinary tract infection) and invasive bacterial infection (IBI; bacteremia, bacterial meningitis) among the following neonates: (1) febrile at presentation (FP), (2) afebrile with history of fever without subsequent fever during hospitalization, and (3) afebrile with history of fever with subsequent fever during hospitalization.METHODS:We performed a single-center retrospective study of neonates evaluated for SBI during emergency department evaluation between January 1, 2006, and December 31, 2017. Patients were categorized into FP, afebrile with no subsequent fever (ANF), and afebrile with subsequent fever (ASF) groups. We compared rates of SBI and IBI between groups using logistic regression and assessed time to fever development using time-to-event analysis.RESULTS:Of 931 neonates, 278 (29.9%) were in the ANF group, 93 (10.0%) were in the ASF group, and 560 (60.2%) were in the FP group. Odds of SBI in neonates ANF were 0.42 (95% confidence interval [CI] 0.23–0.79) compared with infants FP, although differences in IBI were not statistically significant (0.52, 95% CI 0.19–1.51). In infants ASF, median time to fever was 5.6 hours (interquartile range, 3.1–11.4). Infants ASF had higher odds of SBI compared to infants FP (odds ratio 1.93, 95% CI 1.07–3.50).CONCLUSIONS:Neonates with history of fever who remain afebrile during hospitalization may have lower odds for SBI and be candidates for early discharge after an observation period.
The Implementation of Islamic Education Management Information System in Religious Ministry Regional Office West Java Province
Authors: Abadi Dini Husni 
Published: July 2019

EMIS (Education Management Information System) merupakan jawaban atas kebutuhan data dan informasi tentang lembaga-lembaga pendidikan Islam dan lembaga-lembaga lainnya dibawah Ditjen Pendidikan Islam, yakni kebutuhan untuk data dukung di DPR-RI , Bappenas, Kementerian Keuangan, dan lembaga pemerintah lainnya yang berkaitan dan berkepentingan untuk pembangunan dan pengembangan lembaga-lembaga pendidikan Islam di Indonesia, terutama untuk memberikan gambaran lebih jelas, tepat dan akurat serta dapat meyakinkan anggota DPR, Bappenas dan Kementerian serta lembaga-lembaga Pemerintah lainnya agar dapat membantu dan mengupayakan pengembangan dan pembangunan lembaga-lembaga pendidikan Islam, hingga dapat benar-benar sejajar dengan pendidikan umum, yang lebih dulu mendapat dukungan dari pemerintah.
The Use of Stereographic Net for the Rapid Approximate Determination of Distance and Azimuth*
Authors: Willmore P. L. 
Published: July 2019

Abstract
The distance and azimuth from a seismograph station to earthquake epicentres anywhere in the world may be determined simply and rapidly by means of a stereographic chart bearing a suitable family of reference circles. Base charts designed for this purpose are obtainable from the Dominion Observatory, Ottawa.