bluuebunny/crossref_metadata_2025_split huggingface dataset:
FATORES PREDISPONENTES DE ESTRESSE EM ENFERMEIROS QUE ATUAM NA UNIDADE DE TERAPIA INTENSIVA
Authors:   Lorena Campos Santos, Silva Celma Barbosa da , Oliveira Gabriela de Assis , Abdias Letícia Lima 
Published: October 2024

This study aimed to identify the labor stressors in nursing work nurse, at in the Intensive Care Unit. Method: This is a descriptive study by literature integrative review method, where the selected articles include a the years between 2006 and 2023. Results: The results show significant labor difficulties in the professional work unit to significant labor difficulties, including double journey, death of patients, drive management, among others that are certainly present of stress in the nurses work context. Conclusion: institutions reassess the policies directed to the nursing worker and the physical space of their work, and the conditions to which they are subject, focusing a greater appreciation of the professional, thus allowing a quality of life in satisfactory work, and as a result, productivity of service quality.
PRINSIP KOOPERATIF, KESANTUNAN, DAN PARAMATER PRAGMATIK DALAM WACANA HUMOR GUS DUR
Authors: Jupriono D. 
Published: October 2024

This research discusses the verbal humour of Gus Dur from the perspective of speech acts (cooperative principle, politeness principle and pragmatic parameter). With qualitative approach and constructivistic paradigm, this study applies the strategy of text ethnography. By referential identity method and documentation, selection, classification and explanation technique, finally it is known that in the verbal humour of Gus Dur, there are always deviations on the cooperative principle (maxim of quantity, quality, relevance and manner), the polite­ness principle (tact, generosity, approbation, modesty, agree­ment, and sympathy maxim), and pragmatic parameter (distance, power, and rank rating).
JENIS DAN MAKNA ONOMATOPE DALAM ANIME ISEKAI IZAKAYA NOBU KARYA NATSUYA SEMIKAWA
Authors: Rizki Kurniawan Muchamad , Yuana Cuk 
Published: October 2024

Tujuan dari penelitian ini untuk mengklasifikasikan jenis dan mendeskripsikan makna onomatope dalam anime Isekai Izakaya Nobu. Sumber data anime Isekai Izakaya Nobu dipilih karena memiliki banyak kata onomatope tertulis yang jarang ditemukan pada anime lain. Metode penelitian yang digunakan dalam penelitian ini adalah deskriptif kualitatif dengan menggunakan pendekatan semantik. Hasil penelitian terdapat 15 kata onomatope dalam anime ini dengan rincian sebagai berikut: Onomatope jenis giongo terdapat 7 data. Gitaigo terdapat 6 data. Gijougo terdapat 1 data. Giyougo terdapat 1 data. Onomatope jenis gitaigo merupakan jenis yang paling banyak ditemukan, sementara jenis giseigo tidak ditemukan dalam anime ini. Kemudian, makna onomatope yang terkandung adalah hito no yousu/shinjou, mono ga dasu oto, mono no ugoki, dan mono no youtai/seishitsu.
PSYCHOLOGICAL FACTOR AFFECTING ENGLISH STUDENTS WILLINGNESS TO COMMUNICATE IN ENGLISH IN SOCIAL MEDIA
Authors: Saputra Dwi Ando , Saputra Eki , Angraini Ria , Jaya Sinarman 
Published: October 2024

The objective of the research was to find out pyschological factors and dominant factor affecting English Students′ willingness to communicate in English in Social Media. The design of this research was descriptive method. The instrument of the research was questionnaire based on MacIntyre et al. in Tuyen, Thị, & Loan (2019: 253) psychological factor affecting the students willingness to verbal communicate using English in Social Media and the questionnaire adapted from Chotipaktanasook (2017) research. The result of the research were: there are five psychological factors affecting the seventh semester students willingness to communicate in English in social media they are: Self confidence, Perceived communicative competence, learning anxiety, Students’ motivation and Personality. The dominant psychological factors affecting the seventh semester students willingness to communicate in English in social media is students motivation factor. Afterthat in communicate verbally (oral and written) the students more like or dominant use written communicate because it can make the students more confident. From the result, the researcher will give suggestion for the students: It is suggested the students can be more confident to oral communicate using English in social media. The students also diminish their anxiety to be better communicate orally using English in social media and in their daily life.
150 Jahre Maßgeblichkeitsgrundsatz – Zwischenbilanz und Prognose
Authors: Jürgen Marx Franz 
Published: October 2024

Zusammenfassung
Der Beitrag setzt sich mit dem zentralen Bindeglied von handelsund steuerrechtlicher Gewinnermittlung auseinander. Dabei wird angesichts der ersten Regulierung vor einhundertfünfzig Jahren in Bremen ein intensiver Blick auf das Entstehen des Grundsatzes und dessen spätere Entwicklung geworfen. Zugleich gibt das Jubiläum aber auch Möglichkeit zur aktuellen Standortbestimmung. Noch immer liegt keine geschlossene Kodifikation des Steuerbilanzrechts vor, so dass in wesentlichen Bereichen für Ansatz und Bewertung Rückgriffe auf die handelsrechtlichen GoB notwendig sind. Ausgehend von der Bestimmung des Status quo dokumentiert der Beitrag die Entwicklung des Grundsatzes und richtet einen Blick in die Zukunft der steuerrechtlichen Gewinnermittlung.
Der lange Schatten des Unionsrechts auf dem Zivilverfahrensrecht
Authors: Wilke Felix M. 
Published: October 2024

Zusammenfassung
Dieser Beitrag befasst sich mit der Geltung der Charta der Grundrechte der Europäischen Union für das Zivilverfahrensrecht. Die Bindung an die Charta im Bereich des eigenen Verfahrensrechts der EU dürfte als solche kaum kontrovers sein, kann jedoch beispielsweise zur Annahme ungeschriebener Schranken für die Zusammenarbeit in Zivil- und Handelssachen führen. Als deutlich weniger prominent erweist sich dagegen noch die Bindung im Bereich der beschränkten Verfahrensautonomie. Gerade sie könnte weitreichende Folgen zeitigen.
Die (Partei)Prozesshandlung in der ZPO
Authors: Nissen Moritz , Elzer Oliver 
Published: October 2024

Zusammenfassung
Jeder Gerichtsprozess zeichnet sich durch die unmittelbare Interaktion der Parteien untereinander und mit dem jeweiligen Gericht aus. Für den deutschen Zivilprozess lässt sich dieser Befund durch die zentrale Stellung der Parteien unter Geltung von Dispositions- und Beibringungsgrundsatz in besonderem Maße bekräftigen. Dementsprechend wichtig ist das Rechtsinstitut der Prozesshandlung, welches diese Interaktion beschreibt. Der Beitrag hat es zum Ziel, die wesentlichen Voraussetzungen einer wirksamen Vornahme und eines etwaigen Widerrufs bzw. einer Rücknahme von solchen Prozesshandlungen unter Einschluss der wichtigsten Fallkonstellationen herauszuarbeiten und den Wissensstand in Rechtsprechung und Literatur komprimiert darzustellen.
Zinc‐Catalyzed Enantioselective Dearomative [3+2] Cycloaddition Reaction of 3‐Nitrobenzothiophenes and 3‐Nitrothieno[2,3‐b]yridine with 3‐Isothiocyanato Oxindoles
Authors: Yue Deng‐Feng , Zhao Jian‐Qiang , Chen Yong‐Zheng , Zhang Xiao‐Mei , Xu Xiao‐Ying , Yuan Wei‐Cheng 
Published: February 2018

AbstractA highly diastereo‐ and enantioselective dearomative [3+2] cycloaddition reaction of 3‐nitrobenzothiophenes and 3‐nitrothieno[2,3‐b]with 3‐isothiocyanato oxindoles is developed. The reaction is catalyzed by the chiral Zn(OTf)2/bis(oxazoline, and is the second example of a catalytic asymmetric dearomative cycloaddition reaction of 3‐nitrobenzothiophene derivatives. A range of complex heterocyclic compounds containing three contiguous stereocenters, one of which is spirocyclic center, can be obtained in quantitative yields with excellent stereoselectivities.magnified image
Silver‐Catalyzed Decarboxylative Couplings of Acids and Anhydrides: An Entry to 1,2‐Diketones and Aryl‐Substituted Ethanes
Authors: Zou Hua‐Xu , Li Yang , Yang Yuan , Li Jin‐Heng , Xiang Jiannan 
Published: February 2018

AbstractSilver‐catalyzed oxidative decarboxylative couplings of carboxylic acids and anhydrides to produce 1,2‐diketones and substituted ethanes were developed. This reaction allows the generation of acyl or alkyl radicals by decarboxylation of the corresponding α‐keto acids, alkyl acids and anhydrides, which are sequentially coupled to efficiently construct a new C−C bond. This reaction represents a carboxylic acid decarboxylative alternative that employs a radical termination strategy.magnified image
Scholarship by the Clinician‐Educator in Emergency Medicine
Authors: Franzen Douglas , Cooney Robert , Chan Teresa , Brown Michael , Diercks Deborah B. 
Published: February 2018

AbstractEmergency medicine (EM) continues to grow as an academic specialty. Like most specialties, a large number of academic emergency physicians are focused on education of our graduate student learners. For promotion, clinician‐educators (CEs) are required to produce scholarly work and disseminate knowledge. Although promotion requirements may vary by institution, scholarly work is a consistent requirement. Due to the clinical constraints of working in the emergency department, the unique interactions emergency physicians have with their learners, and early adoption of alternative teaching methods, EM CEs’ scholarly work may not be adequately described in a traditional curriculum vitae. Using a rubric of established domains around the academic work of CEs, this article describes some of the ways EM educators address these domains. The aim of the article is to provide a guide for academic department leadership, CEs, and promotion committees about the unique ways EM has addressed the work of the CE.
Effectiveness and safety of anticoagulants for the treatment of venous thromboembolism in patients with cancer
Authors: Streiff Michael B. , Milentijevic Dejan , McCrae Keith , Yannicelli Daniel , Fortier Jonathan , Nelson Winnie W. , Laliberté François , Crivera Concetta , Lefebvre Patrick , Schein Jeff , Khorana Alok A. 
Published: February 2018

AbstractAnticoagulation is used to treat venous thromboembolism (VTE) in cancer patients, but may be associated with an increased risk of bleeding. VTE recurrence and major bleeding were assessed in cancer patients treated for VTE with the most currently prescribed anticoagulants in clinical practice. Newly diagnosed cancer patients (first VTE 1/1/2013‐05/31/2015) who initiated rivaroxaban, low‐molecular‐weight heparin (LMWH), or warfarin were identified from Humana claims data and observed until end of eligibility or end of data availability. VTE recurrence was a hospitalization with a primary diagnosis of VTE ≥7 days after first VTE. Major bleeding events on treatment were identified using validated criteria. Cohorts were compared using Kaplan–Meier rates at 6 and 12 months and Cox proportional hazards models. Cohorts were adjusted for their differences at baseline. A total of 2428 patients (rivaroxaban: 707; LMWH: 660; warfarin: 1061) met inclusion criteria. Patient characteristics were well balanced after weighting. There was a trend for lower VTE recurrence rates in rivaroxaban users compared to LMWH users at 6 months (13.2% vs. 17.1%; P = .060) and significantly lower at 12 months (16.5% vs. 22.2%; P = .030) [HR: 0.72, 95% CI: (0.52‐0.95); P = .024]. VTE recurrence rates were also lower for rivaroxaban than warfarin users at 6 months (13.2% vs. 17.5%; P = .014) and 12 months (15.7% vs. 19.9%; P = .017) [HR: 0.74, 95% CI: (0.56‐0.96); P = .028]. Major bleeding rates were similar across cohorts. This real‐world analysis suggests cancer patients with VTE treated with rivaroxaban had significantly lower risk of recurrent VTE and similar risk of bleeding compared to those treated with LMWH or warfarin.
Supported Porous Nanomaterials as Efficient Heterogeneous Catalysts for CO2 Fixation Reactions
Authors: Bhanja Piyali , Modak Arindam , Bhaumik Asim 
Published: February 2018

AbstractCO2 is a major greenhouse gas responsible for global warming and can act as an abundant and inexpensive C1 source for enhancing the chain length/functionalization of a wide range of reactive organic molecules. It is moderately reactive, nontoxic and renewable. Thus, CO2 fixation reactions are important to meet the global challenges, that is, to mitigate the concentration of CO2 in the atmosphere through its fruitful utilization, which is of great interest from economic and environmental perspectives. Various metallic nanoparticles as well as metal oxides can be supported over high surface area porous materials and the resulting nanomaterial can act as heterogeneous and reusable solid catalyst for CO2 fixation reactions for the synthesis of a large number of fuels, natural products agrochemicals, and pharmaceutical compounds. Here we present an overview of the recent progress as well as promising future of metal/metal oxide nanoparticles supported over porous nanomaterials as heterogeneous catalysts for a wide spectrum of these CO2 fixation reactions.
Influence of Oxidized Oils on Digestibility of Caseins in O/W Emulsions
Authors: Obando Mónica , Soto Erika , De Meulenaer Bruno 
Published: February 2018

The impact of lipid oxidation on protein modifications in emulsions and the consequences on protein digestibility remains unclear. In this study, this impact is evaluated in casein (6 mg mL−1) based emulsions containing oxidized soybean or fish oil (3%) in presence (0.3%) or absence of the emulsifier Tween 20. Emulsions are prepared using oils at three oxidation levels and subsequently the impact on protein digestibility is evaluated after 24 h incubation at 4 °C. Remarkably, protein digestibility increass in emulsions containing medium and highly oxidized fish oil: 70 ± 0.4% and 73 ± 0.4% of the proteins are digested, respectively, whereas protein digestibility in emulsions containing low oxidized fish oil amounted to 63 ± 0.4%. Protein digestibility in emulsions containing soybean oil stabilized by Tween 20 is not influenced by the oxidation level of the oil used. A remarkable tendency is observed for the malondialdehyde content of the emulsions depending on the presence of Tween 20. For soybean oil based emulsions, malondialdehyde concentrations are consistently higher in the presence of Tween 20. On the other hand, for the fish oil based emulsions an opposite trend is observed, except at the highest oxidation level evaluated, for which no significant differences can be detected. It is concluded that the composition of the interface in emulsions depends strongly upon the degree of oil oxidation and the presence of other emulsifiers. If the oil is more oxidized, less protein is present in the interface restricting the impact of lipid oxidation products on the proteins and hence their digestibility.Practical Applications: This research was done to highlight the relevance of the interfacial composition in food emulsions and its influence on dairy protein digestibility. The food industry must be aware of the oil quality and the presence of emulsifiers in foods emulsions that allow to preserve the stability and nutritional characteristics of these food emulsions.This article aims to evaluate the impact of the reactions occurring between lipid oxidation products and proteins in emulsions on protein digestibility. This impact is evaluated in casein based emulsions containing oxidized soybean or fish oil (3%) in presence or absence of an emulsifier (0.3%). Emulsions are prepared using three oxidation levels and subsequently the impact on protein digestibility is evaluated after 24 h incubation at 4 °C. It is concluded that the composition of the interface in emulsions depends strongly upon the degree of oil oxidation and the presence of other emulsifiers.
The Influence of Pt Surface Area on the Photo‐Enhancement of the Methanol Oxidation Reaction
Authors: Odetola Christopher , Trevani Liliana N. , Easton E. Bradley 
Published: February 2018

AbstractThe methanol oxidation reaction (MOR) on both Pt/TiO2/C and Pt/C‐based electrodes can be photo‐enhanced by illuminating the electrodes with UV light. This fact has called into question the role of TiO2 in the photo‐enhancement of MOR when Pt is present. To examine this further, we have studied the change in the photo‐enhancement of methanol electro‐oxidation with Pt surface area. For each catalyst, there was greater MOR activity in the presence of UV‐irradiation. However, upon potential cycling, there was a faster decline in MOR activity in the presence of UV‐irradiation compared to the MOR activity in the dark. A linear relation between the decay in methanol oxidation current with the decay in Pt surface area for both catalysts was observed. This strongly suggests that irradiation enhances the methanol oxidation process on the Pt surface. When TiO2 is present, it has a synergetic electronic effect that further enhances the oxidation process on the Pt surface.
Determination of the speciation and bioavailability of samarium to Chlamydomonas reinhardtii in the presence of natural organic matter
Authors: Rowell Justine-Anne , Fillion Marc-Alexandre , Smith Scott , Wilkinson Kevin J. 
Published: February 2018

Abstract

As technological interest and environmental emissions of the rare earth elements increase, it is becoming more important to assess their potential environmental impact. Samarium (Sm) is a lanthanide of intermediate molar mass that is used in numerous high-technology applications including wind turbines, solar panels, and electric vehicles. The present study relates the speciation of Sm determined in the presence of natural organic matter (NOM) to its bioavailability to the unicellular green alga Chlamydomonas reinhardtii. The free ion concentration was determined using a cation exchange resin (ion exchange technique) in dynamic mode and compared with thermodynamic modeling. Short-term biouptake experiments were performed in the presence of 4 types of NOM: Suwannee River fulvic acids, Pahokee Peat fulvic acids, Suwannee River humic acids, and a Luther Marsh dissolved organic matter isolate (90–95% humic acids). It was clearly shown that even a small amount of NOM (0.5 mg C L−1) resulted in a significant decrease (10 times) in the Sm internalization fluxes. Furthermore, complexation with humic acids (and the corresponding reduction in Sm bioavailability) was stronger than that with fulvic acids. The results showed that the experimentally measured (free) Sm was a better predictor of Sm internalization than either the total concentrations or the free ion concentrations obtained using thermodynamic modeling. Environ Toxicol Chem 2018;37:1623–1631. © 2018 SETAC
Superior bone‐inducing potential of rhBMP9 compared to rhBMP2
Authors: Fujioka‐Kobayashi Masako , Abd El Raouf Mustafa , Saulacic Nikola , Kobayashi Eizaburo , Zhang Yufeng , Schaller Benoit , Miron Richard J. 
Published: February 2018

AbstractRecombinant human bone morphogenic protein (rhBMP) 9 has recently been reported to have more osteopromotive potential in vitro when compared to rhBMP2. The aim of the present study was to investigate the bone‐inducing potential of rhBMP2 and rhBMP9. We compared rhBMP2, rhBMP7, and rhBMP9 at five different concentrations and showed convincingly that rhBMP9 possesses much greater potential for osteoblast differentiation even at 20 times lower concentrations in vitro. We further show that Noggin, an inhibitor for rhBMP2‐induced osteogenesis, did not alter rhBMP9‐induced osteogenesis. Thereafter, we show for the first time that rhBMP9 loaded onto atelo‐collagen membranes is osteoinductive and has greater potential to form ectopic bone formation when compared to rhBMP2 even at four times lower doses. Similarly new bone formation of rhBMP2 and 9 when loaded on deproteinized bovine bone mineral (DBBM) was investigated in a rabbit calvarial defect. At 8 weeks, both rhBMP2 and rhBMP9 induced significantly higher new bone formation when compared to DBBM alone samples. Interestingly, once again four times lower dose of rhBMP9 group induced comparable or even greater levels of new bone height and new bone area when compared to the rhBMP2 group. The present study revealed that (1) rhBMP9 is capable of inducing ectopic new bone formation in vivo and (2) up to four times lower doses of rhBMP9 may be utilized to regenerate same‐size bone defects when compared to rhBMP2. © 2018 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 106A: 1561–1574, 2018.
Opposite impact of Methylene tetrahydrofolate reductase C677T and Methylene tetrahydrofolate reductase A1298C gene polymorphisms on systemic inflammation
Authors: Khalighi Koroush , Cheng Gang , Mirabbasi Seyedabbas , Khalighi Bahar , Wu Yin , Fan Wuqiang 
Published: February 2018

BackgroundMethylenetetrahydrofolate reductase (MTHFR) gene polymorphisms have been found to be related with many diseases. Systemic inflammation is now considered as a major predisposition factor for diseases including diabetes mellitus (DM), coronary arterial disease (CAD), stroke, and cancer. This study aimed to investigate whether systemic inflammation is a possible underlying pathogenesis for MTHFR gene polymorphism‐related disease.MethodsA total of 292 patients were enrolled, and single nucleotide polymorphisms for MTHFR C667T and A1298C were genotyped. Systemic inflammation markers, neutrophil‐to‐lymphocyte ratio (NLR), and platelet‐to‐lymphocyte ratio (PLR) were collected.ResultsIn our study population, MTHFR 677 variants had significant higher NLR level than MTHFR 677 wild type (3.77 ± 0.26 vs 3.06 ± 0.18, P = .028). Logistic regression analysis showed that MTHFR 677 variants were significantly associated with increased NLR level. MTHFR 1298 variants showed the opposite effects which tended to have lower level of NLR (3.21 ± 0.16 vs 3.79 ± 0.34, P = .087) and PLR (137.0 ± 4.8 vs 157.7 ± 9.4, P = .052) than MTHFR 1298 wild type. General linear model showed that there was no statistically significant interaction between MTHFR C667T and A1298C gene polymorphism on NLR or PLR.ConclusionsThis study indicates that MTHFR C677T and MTHFR A1298C gene polymorphisms have opposite effect on systemic inflammation, and systemic inflammation may contribute to the pathogenesis for diseases associated with MTHFR C667T gene polymorphism.
Maternal thyroid‐stimulating hormone reference ranges for first trimester screening from 11 to 14 weeks of gestation
Authors: Šálek Tomáš , Dhaifalah Ishraq , Langova Dagmar , Havalová Jana 
Published: February 2018

BackgroundTo establish maternal thyroid‐stimulating hormone (TSH) reference ranges for first trimester screening from 11 + 0 to 13 + 6 weeks of gestation.MethodsA total of 10 592 singleton and 201 twin consecutive Caucasian pregnant women who underwent simultaneously prenatal first trimester Down's syndrome screening and thyroid function screening from January 2010 to November 2017 were included in the study. Women with positive antithyroid peroxidase antibody (TPOAb) and positive personal history of thyroid disease were previously excluded. TSH was measured by immunochemiluminescent assay on ci 16200 Abbott Architect analyzer. Nonparametric percentile method (also known as CLSI C28.A3) was used for the determination of reference ranges.ResultsWe established reference ranges of TSH for the period of gestation from 11 + 0 to 13 + 6 weeks of pregnancy as 0.16‐3.43 mU/L for singleton Caucasian pregnancies and 0.02‐2.95 mU/L for twin Caucasian pregnancies. The median (IQR) of TSH for singleton pregnancies was higher than that for twin pregnancies (1.25 mU/L (0.83‐1.81) vs 0.84 (0.37‐1.47), respectively; P < .0001).ConclusionsEach first trimester screening center should be aware of which type of immunoassay their laboratory uses. TSH reference ranges in women during the first trimester of pregnancy are lower than those for general population. Twin pregnancies have lower TSH than singleton pregnancies.