bluuebunny/crossref_metadata_2025_split huggingface dataset:
Substituição do milho moído pela glicerina como aditivo em silagem de capim elefante
Authors: Tonin T. J. , Viégas J. , Silveira A. M. , Moro G. , Pereira S. N. , Dotto L. R. , Sebastiany L. , Leonarde J. V. , Schumacher L. L. 
Published: December 2018

Objetivou-se com este estudo testar o aumento linear da inclusão de glicerina bruta (86% de pureza) em substituição ao milho moído, como aditivo, na forragem de capim-elefante destinada a ensilagem, avaliando-se a qualidade nutricional do alimento e a viabilidade da ensilagem do material. Foram testados cinco níveis de substituição do milho pela glicerina em taxas que variaram de 3,12 a 12,5% sobre a matéria natural da forragem, além de um tratamento controle (apenas forragem). Realizaram-se análises bromatológicas e de digestibilidade para avaliar o valor nutricional da mistura durante a ensilagem e após o processo fermentativo, na silagem. Para avaliar a qualidade fermentativa foram feitas avaliações de pH, nitrogênio amoniacal, recuperação de matéria seca e densidade. A inclusão do milho moído incrementou (P<0,05) o teor de matéria seca em até 28%, tanto na forragem fresca, bem como na silagem. Tanto a inclusão do milho, bem como a substituição deste pela glicerina resultou (P<0,05) em um incremento médio de 25% e 32 % na digestibilidade in situ e valor energético da silagem, respectivamente quando comparado ao capim puro. Isto, devido ao decréscimo (P<0,05) dos teores de fibra em detergente neutro e fibra em detergente ácido na silagem. A inclusão de glicerina aumentou (P<0,05) as perdas de proteína bruta durante a fermentação e diminuiu a recuperação da matéria seca. O teor de matéria seca da forragem parece ser fator chave para o sucesso de inclusão da glicerina como aditivo na ensilagem do capim-elefante, no intuito de evitar perdas expressivas de qualidade nutricional durante a fermentação.
La gig economy y la obligación de coordinar la seguridad y salud de sus "autónomos" = The gig economy and the obligation to coordinate the security and health of their self-employed
Authors: Álvarez Cuesta Henar 
Published: December 2018

El artículo analiza, en primer lugar, la construcción jurídico-laboral de las prestaciones de servicios vía aplicación o plataforma tecnológica para su consideración como redes de empresa; en segundo término, las obligaciones en materia de coordinación de actividades existentes entre las empresas que colaboran entre ellas y su posible aplicación en el marco de la economía colaborativa; para, en un último apartado, avanzar en las exigencias de protección de la salud y seguridad de los trabajadores (por cuenta propia o ajena) de estas actividades para extender determinadas obligaciones de las empresas concurrentes o incluso de la principal, a las mismas. The paper analyzes, in the first place, the legal construction of the service provision via application or technological platform for their consideration as business networks; secondly, the obligations regarding the coordination of enterprises among the companies that collaborate among them and their possible application within the framework of the collaborative economy; to, in a final section, advance in the requirements of protection of risk prevention (of workers, employees or self employed) of these activities in order to extend certain obligations of the concurrent companies or even of the principal, to them.
Characteristics of Kombucha Fermentation from Different Substrates and Cytotoxicity of Tea Broth
Authors: Quiao-Won Maria Elma , Teves Franco G. 
Published: December 2018

Kombucha is made from sweetened tea fermented by a symbiotic culture of bacteria and yeast consumed worldwide because of its potentially beneficial effects on health. However, there are only few studies on the safety of kombucha consumption that will establish it as a functional beverage. The present study compared, pH, temperature and sugar content of different tea mixtures of black or green tea as nitrogen sources and white and brown sugar as carbon sources in a 30-day fermentation period. A marked decrease in pH was observed throughout fermentation with Green tea-White (GW) sugar mixture showing the lowest recorded pH value of 2.37 on the 14th day of fermentation. Temperature is essential in the fermentation process and thus maintained at ambient 29±1°C. Black and green teas with white sugar (7°Brix) showed to have higher sugar level compared to tea mixtures with brown sugar (5°Brix). Brine Shrimp Lethality Assay was carried out to determine cytotoxicity of kombucha. The four substrate combinations have very low LC50 values with Black tea-Brown sugar (BB) mixture showing to have the lowest in both acute and chronic effects (0.073 ppm and 0.101 ppm, respectively). This indicates safety of kombucha for consumption.
EFFICACY OF CAPTOPRIL, MOXONIDINE AND THEIR COMBINATIONS WITH NIFEDIPINE IN THE NON-THREATENING HYPERTENSION
Authors: Ruksin V. V. , Grishin O. V. , Chiritso M. M. , Malakhov A. N. , Onuchin M. V. 
Published: December 2018

Objective. To study several medications and their combinations in non-threatened hypertension worsening captopril, and moxonidine, captopril + nifedipine, captopril + moxonidine.Design and methods. We include326 patients (253 females) aged 45–89 years who referred for the urgent health care due to the non-threatene hypertension worsening. Mean duration of hypertension was 20,6 ± 0,6 years. Special questionnaires were ﬁlle in, heart rate, blood pressure by Korotkoff method, and electrocardiogram were registered.Results. Moxonidinwas shown to be more effective in patients with the sympathetic hyperactivity, captopril — in patients withouincreased sympathetic activity. The combination of captopril and nifedipine was associated with the reductioof therapy efﬁ ciency, and the combination of moxonidine and nifedipine — with its increase. Moreover, administration of captopril and nifedipine led to the higher rate of side effects, compared to the combination moxonidine and nifedipin.
THE EFFECT OF THE 8-WEEK ATORVASTATIN TREATMENT ON THE QUALITY OF LIFE OF HYPERTENSIVE PATIENTS WITH METABOLIC SYNDROME
Authors: Bespalova I. D. , Kalyuzhin V. V. , Ryazantseva N. V. , Medyantsev Yu. A. , Murashev B. Yu. , Osikhov I. A. 
Published: December 2018

Objective.To study the effect of the 8-week treatment with atorvastatin on the quality of life (QOL) of hypertensive patients with metabolic syndrome.Design and methods.An 8-week open prospective study included 35 patients with essential hypertension (stage II), associated with metabolic syndrome. Along with the complete clinical, laboratory and instrumental examination, taken in a specialized cardiology clinic, MOS SF-36® questionnaire was used to study the QOL during atorvastatin treatment.Results and conclusions.The 8-week atorvastatin treatment (20 to 40 mg/day titrated individually) both contributes to statistically signifi cant reduction of atherogenic fractions of cholesterol and provides a positive dynamics of subjective evaluation of QOL by SF-36® scales in hypertensive patients with metabolic syndrome.
RENAL SYMPATHETIC DENERVATION FOR THE TREATMENT OF RESISTANT HYPERTENSION — SAFETY CONTROL BY ULTRASOUND TECHNIQUE
Authors: Ripp T. M. , Mordovin V. F. , Pekarskiy S. E. , Ryabova T. R. , Zlobina M. V. , Krilov A. L. , Lechikaki V. A. , Popov S. V. , Karpov R. S. 
Published: December 2018

Objective.To assess the safety of transcatheter radiofrequency denervation (TRFD) of renal arteries (RA) in patients with resistant hypertension (RH) by ultrasound of the kidneys.Design and methods.We assessed estimated glomerular filtration rate (eGFR) and performed ultrasound examination of the kidneys and RA at 1, 24 and 48 weeks after TRFD in 35 patients (mean age — 52 +- 10 years) with blood pressure (BP) > 160/100 mmHg despite 3 full-dose antihypertensive drugs as a part of the single-center prospective safety/efficacy study (NCT01499810). Results.Office BP decreased by 34,9/18,2 mmHg (p < 0,001/0,001) and -42,7/-21,7 mmHg (p < 0,01/0,01) at 24 and 48 weeks after TRFD, respectively. No significant changes of eGFR and renal blood flow were found, however, the resistive index (RI) decreased significantly in segmental RA: from 0,62 Ѓ} 0,05 initially till 0,58 +-0,06 and 0,59 +- 0,06, respectively, at follow-up points (p = 0,003; p = 0,049 and p =0,063).Conclusions.TRFD of RA has no adverse effect on either renal function or blood flow in the trunk and segmental branches of the RA. On the contrary, the decrease of resistive index in segmental RA after the intervention indicates improvement of renal blood flow.
THE BENEFITS OF ANGIOTENSIN II RECEPTOR ANTAGONISTS I TYPE IN HYPERTENSIVE PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME
Authors: Sviryaev Yu. V. , Zvartau N. E. , Korostovtseva L. S. , Kalinkin A. L. , Konradi A. O. , Shlyakhto E. V. 
Published: December 2018

Objective.To assess efficiency of angiotensin II converting enzyme inhibitor Perindopril versus angiotensin II receptor blocker Telmisartan in hypertensive patients with obstructive sleep apnea syndrome (OSAS).Design and methods.Sixty hypertensive patients with OSAS (non-CPAP-users) were enrolled in a randomized controlled open study: 48 males and 12 females; mean age — 56,2 ± 9,5 years; hypertension duration — 12,5 ± 7,4 years; body mass index — 32,0 ± 5,9 kg/m2, apnea-hypopnea index (AHI) — 35,4 ± 24,2 episodes per hour of sleep. All patients were divided into 2 groups: patients (n = 30) from the 1st group got Telmisartan 40 mg daily (titrated up to 80 mg daily if necessary), and Perindopril 4 mg daily (titrated up to 8 mg daily) was prescribed to 2nd group (n = 30). The treatment lasted for 12 weeks. Results.Twenty three patients in Telmisartan group and 24 patients in Perindopril group achieved goal blood pressure (< 140/90 mmHg) (χ2 = 1,23; p > 0,05), all patients got maximal doses of medications. The reduction of offi ce and 24-hour blood pressure was comparable in both groups. Circadian blood pressure profi le was normalized in 17 patients from Telmisartan group and in 9 patients from Perindopril group (χ2 = 6,21; p < 0,05). At the same time AHI decreased by 19 episodes per hour of sleep in Telmisartan group, while it increased by 10,1 episodes per hour of sleep in Perindopril group (p < 0,01).Conclusion.Telmisartan treatment is beneficial in hypertensive obese patients with OSAS compared to Perindopril due to the reduction of OSAS severity (assessed by AHI) leading to the normalization of circadian blood pressure profile.
SPECULATIONS ОN BLOOD PRESSURE INCREASE MECHANISMS IN RENAL ARTERY CLIPPED WISTAR RATS
Authors: Kuzmenko N. V. , Pliss M. G. , Rubanova N. S. , Tsyrlin V. A. 
Published: December 2018

Objective.To examine the mechanisms underlying the activation of the sympathetic nervous system and blood pressure elevation in vasorenal hypertension in the male Wistar rats weighing 250–300 g.Design and methods.We observed the development of renovascular hypertension, beat-to-beat interval and heart rate variability in animals with intact renal nerves and denervated ischemic kidney for 8 weeks after renal artery clamping. Eight weeks later after renal artery clamping in hypertensive rats with denervated ischemic kidney, both-sided renal denervation was performed, and blood pressure was monitored for 6 weeks.Results.Although the ischemic kidney denervation reduces the activity of the sympathetic nervous system, it does not prevent renovascular hypertension development. However, both-sided renal denervation leads to the normalization of blood pressure in the rats with stable renovascular hypertension.Conclusion.We suggest that increased afferent fl ow from structural formations of the ischemic kidney plays an important role for the increased sympathetic nervous system activity.
APNEA IN INFANTS WITH BRONCHOPULMONARY DYSPLASIA DEPENDING ON ITS SEVERITY
Authors: Petrova N. A. , Dobrodeeva I. V. , Shabalov N. P. , Ivanov .. O. , Petrenko V. V. , Kiseleva N. S. , Mamaeva T. V. 
Published: December 2018

Objective. To evaluate bronchopulmonary dysplasia (BPD) impact on apnea incidence and characteristics in infants.Design and methods. We performed cardiorespiratory monitoring in 25 premature infants with BPD and 25 non-BPD preterms comparable in gestational age (26–30 weeks) at ages of less than 29 days, 29–50 days and > 50 days. Results. Infants with moderate to severe BPD tended to have higher apnea incidence when older than 50 days, and more obstructive episodes, compared to infants with mild BPD and without BPD. Infants with mild BPD had similar apnea type ratio as non-BPD infants. In the second and third age intervals, infants with moderate to severe BPD demonstrated similar prolonged apnea incidence but had rather more apnea accompanied by oxygen saturation (SрO2) falls ≤ 80 %, compared to infants with mild BPD and without BPD. During the irst month infants with mild BPD demonstrated shorter apnea episodes, less prolonged apnea and more apnea with SрO2≤80 % falls compared to non-BPD infants. During the second age interval these characteristics did not differ between the groups. Conclusion. Infants with moderate to severe BPD had longer apnea persistence, more signiicant SрO2falls due to apnea. Respiratory control characteristics seem to be comparable in mild BPD and non-BPD infants from the second month of age.
Faculty Members’ Perceptions of Quality Assurance and Accreditation in Afghanistan
Authors: Mussawy Sayed Ahmad Javid , Rossman Gretchen B 
Published: December 2018

Abstract
This study investigated faculty members’ perceptions of quality assurance and accreditation (QAA) in Afghanistan. The study aimed to examine how familiar faculty members were with QAA policy, quality concepts, QAA processes, and whether QAA process has improved the status quo. Through a sequential exploratory mixed methods design, the investigators interviewed seven faculty members at four universities, and subsequently conducted a self-administered survey questionnaire at six universities (two public and four private). A response rate of 54 percent (N = 42) was obtained from the survey. The study findings suggest that faculty members had mixed impressions about QAA implementation. For instance, an overall sum of mean scores shows that faculty members have a positive view about QAA processes M = 3.5 (SD = .75), however, interview participants were less satisfied with QAA outcome. Lastly, implications are made that a successful implementation of QAA processes in Afghanistan is contingent on: 1) establishment of a quality culture wherein universities own the processes and outcomes, and 2) engagement of key stakeholders including faculty, staff, and administrators to internalize QAA processes to improve the status quo.
Keywords: higher education quality; quality assurance; accreditation; higher education in Afghanistan
Uma flautista francesa em múltiplos caminhos brasileiros – entrevista com Odette Ernest Dias
Authors: Penna Maura 
Published: December 2018

Na tarde de 12 de agosto de 2018, numa atmosfera de inverno carioca, estive com a Prof.ª Odette Ernest Dias, então com 89 anos, em seu apartamento em Santa Teresa. Tendo sido sua aluna na Universidade de Brasília (UNB), considerando-a como amiga e pessoa importante em minha própria trajetória musical e acadêmica, há muito queria poder ir ao Rio de Janeiro para esta conversa sobre seu percurso musical e docente. Nesse encontro – que, por morarmos em cidades distantes, teve que ser agendado com antecedência –, falamos de muitas coisas, e pude colher seu relato de caminhos e memórias, que refletem a sua longa e rica – e por que não dizer admirável – história de vida.
De Broglie Wave Analysis of the Heisenberg Uncertainty Minimum Limit under the Lorentz Transformation
Authors: Putra Fima Ardianto 
Published: December 2018

A simple analysis using differential calculus has been done to consider the minimum limit of the Heisenberg uncertainty principle in the relativistic domain. An analysis is made by expressing the form of and based on the Lorentz transformation, and their corresponding relation according to the de Broglie wave packet modification. The result shows that in the relativistic domain, the minimum limit of the Heisenberg uncertainty is p x ?/2 and/or E t ?/2, with is the Lorentz factor which depend on the average/group velocity of relativistic de Broglie wave packet. While, the minimum limit according to p x ?/2 or E t ?/2, is the special case, which is consistent with Galilean transformation. The existence of the correction factor signifies the difference in the minimum limit of the Heisenberg uncertainty between relativistic and non-relativistic quantum. It is also shown in this work that the Heisenberg uncertainty principle is not invariant under the Lorentz transformation. The form p x ?/2 and/or E t ?/2 are properly obeyed by the Klein-Gordon and the Dirac solution.
Key words: De Broglie wave packet, Heisenberg uncertainty, Lorentz transformation, and minimum limit.
Calculation of line of site periods between two artificial satellites under the action air drag
Authors: Ammar M. K. , Amin M. R. , Hassan M.H.M. 
Published: December 2018

Abstract
In a previous (herein referred to as Ammar, Amin and Hassan Paper [1]) the statement of the problem was formulated and the basic visibility function between two satellites in terms of the orbital elements and time were derived. In this paper the perturbing effect due to drag force on the visibility function were derived explicitly up to O(e
4), by using Taylor’s expansion for the visibility function about certain epoch. We determine the rise and set times of the satellites through the sign of the visibility function. Numerical examples were worked out for some satellites in order to check the validity of the work.
Visibility intervals between two artificial satellites under the action of Earth oblateness
Authors: Ammar M. K. , Amin M. R. , Hassan M.H.M. 
Published: December 2018

Abstract
This paper presents an analytical method to determine the rise-set times of satellite-satellite visibility periods in different orbits. The Visibility function in terms of the orbital elements of the two satellites versus the time were derived explicitly up to e
4. The line-of-sight corrected for Earth Oblateness up to J
2, were considered as a perturbation to the orbital elements. The visibility intervals of the satellites were calculated for some numerical examples in order to test the results of the analytical work.
Convexity result and trees with large Balaban index
Authors: Knor Martin , Škrekovski Riste , Tepeh Aleksandra 
Published: December 2018

Abstract
Balaban index is defined as

J

(
G
)

=

m

m
−
n
+
2

Σ

1

w

(
u
)

⋅
w

(
v
)

,

$J\left( G \right)=\frac{m}{m-n+2}\Sigma \frac{1}{\sqrt{w\left( u \right)\cdot w\left( v \right)}},$

where the sum is taken over all edges of a connected graph G, n and m are the cardinalities of the vertex and the edge set of G, respectively, and w(u) (resp. w(v)) denotes the sum of distances from u (resp. v) to all the other vertices of G. In 2011, H. Deng found an interesting property that Balaban index is a convex function in double stars. We show that this holds surprisingly to general graphs by proving that attaching leaves at two vertices in a graph yields a new convexity property of Balaban index. We demonstrate this property by finding, for each n, seven trees with the maximum value of Balaban index, and we conclude the paper with an interesting conjecture.
Availability of Healthier Children’s Menu Items in the Top Selling Quick Service Restaurant Chains (2004–2015)
Authors: Mueller Megan P. , Wilde Parke , Folta Sara C. , Anzman-Frasca Stephanie , Economos Christina D. 
Published: December 2018

Objectives. To describe time trends in the availability of healthier children’s menu items in the top selling quick service restaurant (QSR) chains. Methods. We used Technomic Inc.’s MenuMonitor to construct a data set of side and beverage items available on children’s menus from 2004 to 2015 at 20 QSR chains in the United States. We evaluated the significance of time trends in the average availability of healthier fruit and nonfried vegetable sides and nonsugary beverages offered as options and by default in children’s meal bundles. Results. Healthier sides and beverages offered as options increased by 57.5 and 25.0 percentage points, respectively, from 2004 to 2015 but leveled off starting in 2013. Healthier items bundled by default also increased during this time frame, with most adoption occurring after 2010. However, these items remain relatively uncommon, with less than 20% of meal bundles including healthier items by default. All tests evaluating time trends in the availability of healthier items in meal bundles were significant at P < .001. Conclusions. The QSRs evaluated made improvements in the quality of sides and beverages offered on children’s menus from 2004 to 2015. Additional efforts are needed to increase the percentage of healthier options offered by default.
Cost-Effectiveness of a US National Sugar-Sweetened Beverage Tax With a Multistakeholder Approach: Who Pays and Who Benefits
Authors: Wilde Parke , Huang Yue , Sy Stephen , Abrahams-Gessel Shafika , Jardim Thiago Veiga , Paarlberg Robert , Mozaffarian Dariush , Micha Renata , Gaziano Thomas 
Published: December 2018

Objectives. To estimate the health impact and cost-effectiveness of a national penny-per-ounce sugar-sweetened beverage (SSB) tax, overall and with stratified costs and benefits for 9 distinct stakeholder groups. Methods. We used a validated microsimulation model (CVD PREDICT) to estimate cardiovascular disease reductions, quality-adjusted life years gained, and cost-effectiveness for US adults aged 35 to 85 years, evaluating full and partial consumer price pass-through. Results. From health care and societal perspectives, the SSB tax was highly cost-saving. When we evaluated health gains, taxes paid, and out-of-pocket health care savings for 6 distinct consumer categories, incremental cost-effectiveness ratios ranged from $20 247 to $42 662 per quality-adjusted life year for 100% price pass-through (incremental cost-effectiveness ratios similar with 50% pass-through). For the beverage industry, net costs were $0.92 billion with 100% pass-through (largely tax-implementation costs) and $49.75 billion with 50% pass-through (largely because of partial industry coverage of the tax). For government, the SSB tax positively affected both tax revenues and health care cost savings. Conclusions. This stratified analysis improves on unitary approaches, illuminating distinct costs and benefits for stakeholders with political influence over SSB tax decisions.
Carfentanil-Associated Mortality in Wayne County, Michigan, 2015–2017
Authors: King Andrew , Foley Daniel , Arfken Cynthia , Aaron Cynthia , Sung Lokman , Hlavaty Leigh 
Published: December 2018

Objectives. To identify opioids associated with a spike in opioid-related mortality in Wayne County, Michigan, from July 2016 through February 2017. Methods. We reviewed records from the Wayne County Medical Examiner’s Office of 645 people who died because of accidental nonmedically prescribed opioid overdoses from July 2015 through July 2017. We analyzed basic demographics, locations of death, and all opioid toxicology results. Decedents who died in hospitals were excluded. Results. Of the 645 people who died because of nonmedically prescribed opioid overdoses, 65% were male and 63% were White, with an average age of 43 years. Carfentanil was detected in 129 (20%) cases. During the 8-month mortality spike, carfentanil was detected in 114 of 419 cases (average = 27.2%; range = 6.4%–45.2%). Substances most frequently detected with carfentanil included morphine (57%), 6-monoacetylmorphine (38%), fentanyl (43%), norfentanyl (33%), tetrahydrocannabinol (34%), and cocaine (29%). Conclusions. The Wayne County spike in mortality temporally corresponded with the detection of carfentanil and a proportional increase in opioid overdose deaths with detectable carfentanil. Public Health Implications. The abrupt decrease in carfentanil-detected mortality coincided with an announcement indicating an impending ban on fentanyl analogs from China, which suggests that source control is an effective countermeasure.