bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phytochemical Profile and Bioactivity of Essential Oil from Pimenta Dioica Leaves on Cowpea Beetle, Callosobruchus Maculatus (F.) (Coleoptera: Bruchidae): A Farmer Friendly Solution for Postharvest Pest Management
Authors: P.C.R.K Tenne , M.M.S.C Karunaratne 
Published: October 2018

Abstract
Pimenta dioica (Allspice) leaf essential oil was isolated using hydro-distillation and insecticidal properties were evaluated for their ability to suppress post-harvest insect pest Callosobruchus maculatus in storage legumes and pulses. Four concentrations of leaf oil (0.5, 0.6, 0.8 and 1.0 v/v% ) were tested to evaluate their contact and fumigation repellency as well as insecticidal activities. Volatile organic compounds of leaf oil were analyzed by headspace solid-phase micro extraction coupled with gas chromatography and mass spectrometry (HS-SPME/GCMS) using polar and medium polar fibers. All concentrations elicited significantly higher repellent effects on insects after 2 hour exposure when compared with those of the control with the highest concentration producing 98.0% and 92.0% contact and fumigation repellency effects. Contact and fumigation toxicity tests exhibited 100% mortality for the highest concentration after 6 and 12 hour exposure respectively giving low LC50 values of 0.3 (v/v%). Volatile oil analysis indicated that the leaf essential oil comprised of high amount of Eugenol (89.8%), Methyl eugenol (2.3%) and caryophyllene (4.1%) for the polar fiber. Eugenol (42.6%), Caryophyllene (27.9%), Humulene (6.8%) and 1,8 Cineol (8.1%) were obtained for the medium polar fiber. Results indicate that the leaf essential oil of P.dioica would be a safe, eco-friendly alternative botanical insecticide in managing C.maculatus during storage.
Speciation of technetium in carbonate media under helium ions and γ radiation
Authors: Ghalei Mohammad , Vandenborre Johan , Poineau Frederic , Blain Guillaume , Solari Pier-Lorenzo , Rôques Jerome , Haddad Ferid , Fattahi Massoud 
Published: October 2018

Abstract
Technetium carbonates complexes produced by chemical, electrochemical and radiolytic methods have been studied by UV-Visible, X-ray Absorption Fine Structure (XAFS) and Density Functional Theory methods. The (NH4)2TcCl6 salt was dissolved in 2 M KHCO3. The resulting purple solution was analyzed by XAFS and UV-Visible spectroscopy. The UV-Visible spectra exhibits a band centered at 515 nm. The XAFS results were consistent with the presence of polymeric species containing the [Tc2(μ−O)2]4+ core coordinated to carbonate ligand. Concerning the electrochemical methods, the pertechnetate anion was electrochemically reduced in concentrated carbonate solution [(CO3
2−)=5 M and (HCO3
−)=0.5 M]. For the radiolytic reduction, the speciation of Tc under Helium ions particle beam and γ radiation was examined by UV-Visible and XAFS spectroscopy in high concentrated carbonate media. In concentrated carbonate solutions, pertechnetate as Tc(VII), was not reduced under irradiation due to the formation of carbonate radical which is a strong oxidant. Then, the solution proposed was the addition of formate to the solution which can scavenge hydroxyl radical 10 times faster than carbonate and prevent re-oxidation of reduced technetium. The XANES and EXAFS spectroscopies, approved by theoretical methods, revealed that the final product of the radiolytic reduction of pertechnetate is in the +IV oxidation state. The final structure of the reduced product by He2+ radiolysis was the same as electrochemical reduction. From this complex determination and evolution vs. the dose, this study is reporting the solubility of the Tc(IV) complex.
Gravitational Drift Instability in Quantum Dusty Plasmas
Authors: Jamil M. , Mir Zahid , Rasheed A. , Hussain A. 
Published: October 2018

AbstractThe dispersion relation of electrostatic waves due to multi-drifts is studied in an ambient magnetic field across three-species quantum dusty plasmas. The quantum hydrodynamic model is applied to analyze the effects of the Lorentz and the gravitational forces. It is found that the instability is excited mainly due to theE0×B0\({\mathbf{E}_{0}}\times{\mathbf{B}_{0}}\)drift of the plasma species. However, an additionalg0×B0\({\mathbf{g}_{0}}\times{\mathbf{B}_{0}}\)drift associated with dust particles enhances the instability over a wide spectrum of wavevector. The role of a varying magnetic field and the number density of electrons in the wave instability are analyzed graphically. It is noticed that these factors have a significant contribution over the drift instability.
Biphasic Modulation of NMDA Receptor Function by Metabotropic Glutamate Receptors
Authors: O'Neill Nathanael , McLaughlin Catherine , Komiyama Noboru , Sylantyev Sergiy 
Published: October 2018

A recently reported rapid potentiation of NMDA receptors by Group I metabotropic glutamate receptors (mGluRIs) via a Homer protein link is distinct from the classical, relatively slow inhibitory G-protein-associated signaling triggered by mGluRI activation. The relationship between these two mechanisms remains unknown. Here, we focused on the mGluRI-dependent modulation of NMDAR response in hippocampal dentate gyrus granule cells and cerebellar granule cells of C57BL6-J mice and found that these two contrasting mechanisms overlap competitively on the time scale from hundreds of milliseconds to seconds, with the net effect depending on the cell type. At a shorter time interval (units of millisecond), the Homer-mediated signal from mGluRIs prevails, causing upregulation of NMDAR function, in both dentate gyrus granule cells and cerebellar granule cells. Our results shed light on the possible mechanisms of anti-schizophrenia drugs that disrupt Homer-containing protein link.SIGNIFICANCE STATEMENTHere we study modulation of NMDA receptors triggered by activation of metabotropic glutamate receptors Group I via two distinct pathways: classical G-protein signaling system and newly discovered high-speed modulatory mechanism associated with Homer-protein-containing direct molecular link. We found that these two contrasting mechanisms overlap competitively on the time scale from hundreds of milliseconds to seconds, with the net effect depending on the cell type. We have also found that both crosstalk mechanisms cause significant changes in synaptic strength and plasticity. Our results resolve an apparent discrepancy between earlier studies that demonstrated contradictive effects of Homer-containing protein link disruption on NMDA receptor signaling. On top of that, our data provide a plausible explanation for unclear action mechanisms of anti-schizophrenia drugs.
The precarious freshwater resources of Sable Island, Nova Scotia, Canada: Occurrence and management considerations
Authors: Hennigar Terry W. , Kennedy Gavin W. 
Published: October 2018

This paper presents an overview of the hydrogeology and the freshwater resources of Sable Island, Nova Scotia. The role of the sand deposits, morphology and dynamics of the dune structures and systems, precipitation, and tidal influences are discussed. The distribution, quality, and importance of both surface water and groundwater resources of the island are also presented. Fresh groundwater on the Island occurs in an unconfined sand lens aquifer. Studies to date on the hydrogeology of the island have shown highly variable rates of precipitation, both seasonally and annually, which in combination with the influence of shifting dune structures contribute to a dynamic freshwater /saltwater balance. Infiltration rates into the permeable aquifer system are greater than precipitation rates, precluding surface water flow.The chemical quality of water in the freshwater lens aquifer is generally good and meets the Guidelines for Canadian Drinking Water Quality. The aquifer is vulnerable to surface contamination, however, due to its shallow, unconfined nature, and any water supply wells are highly likely to be classified as being ‘under the direct influence of surface water’ (GUDI). Under these conditions a multi-barrier source water protection plan is considered essential for managing future public drinking water supplies on the Island. Recommendations for future studies, including long-term monitoring of water level trends, are provided to support the sustainable use of groundwater on the Sable Island.
The trout fishery of the upper Medway watershed, Nova Scotia, 2016-17
Authors: Lavers Amanda J. , Headley Jason N. , MacMillan John L. , Reid Darrin 
Published: October 2018

During the spring of 2016 and 2017, the Mersey Tobeatic Research Institute (MTRI), in collaboration with the Nova Scotia Department of Fisheries and Aquaculture, conducted an angler creel survey in the Medway Lakes Wilderness Area that is located within the upper Medway watershed. Since 2012, public access to this region was improved to numerous lakes and streams, increasing the risk of overexploitation and the illegal introduction of invasive fish species. The purpose of this study was to assess the current status of the fishery for Brook trout, Salvelinus fontinalis, investigate the possible presence of invasive Smallmouth bass, Micropterus dolomieu, and Chain pickerel, Esox niger, and inform anglers of the effects of invasive species on local biodiversity. Over the course of this two-year study, a total of 264 anglers spent 1017 hours to catch 1279 trout, of which 74% were released. Median length of retained Brook trout was of 25 cm and the maximum length was 43 cm. The majority of the catch was 2+ and 3+ years old. Angler catch rates were similar to nearby Kejimkujik National Park and greater than in the Tangier Grand Lakes Wilderness Area. The study area does not currently appear to be inhabited by invasive fish species. Most of the anglers interviewed lived nearby and had a long history of fishing in the upper Medway watershed. The study provides baseline data from the trout fishery which could be used to evaluate management strategies and future impacts of invasive fish species.
Genomic Signatures of Adaptation to a Precipitation Gradient in Nigerian Sorghum
Authors: Olatoye Marcus O , Hu Zhenbin , Maina Fanna , Morris Geoffrey P 
Published: October 2018

Abstract
Evolution of plants under climatic gradients may lead to clinal adaptation. Understanding the genomic basis of clinal adaptation in crops species could facilitate breeding for climate resilience. We investigated signatures of clinal adaptation in the cereal crop sorghum (Sorghum bicolor L. [Moench]) to the precipitation gradient in West Africa using a panel (n = 607) of sorghum accessions from diverse agroclimatic zones of Nigeria. Significant correlations were observed between common-garden phenotypes of three putative climate-adaptive traits (flowering time, plant height, and panicle length) and climatic variables. The panel was characterized at &gt;400,000 single nucleotide polymorphisms (SNPs) using genotyping-by-sequencing (GBS). Redundancy analysis indicated that a small proportion of SNP variation can be explained by climate (1%), space (1%), and climate collinear with space (3%). Discriminant analysis of principal components identified three genetic groups that are distributed differently along the precipitation gradient. Genome-wide association studies were conducted with phenotypes and three climatic variables (annual mean precipitation, precipitation in the driest quarter, and annual mean temperature). There was no overall enrichment of associations near a priori candidate genes implicated in flowering time, height, and inflorescence architecture in cereals, but several significant associations were found near a priori candidates including photoperiodic flowering regulators SbCN12 and Ma6. Together, the findings suggest that a small (3%) but significant proportion of nucleotide variation in Nigerian sorghum landraces reflects clinal adaptation along the West African precipitation gradient.
Comparative Genomics Approaches Accurately Predict Deleterious Variants in Plants
Authors: Kono Thomas J Y , Lei Li , Shih Ching-Hua , Hoffman Paul J , Morrell Peter L , Fay Justin C 
Published: October 2018

AbstractRecent advances in genome resequencing have led to increased interest in prediction of the functional consequences of genetic variants. Variants at phylogenetically conserved sites are of particular interest, because they are more likely than variants at phylogenetically variable sites to have deleterious effects on fitness and contribute to phenotypic variation. Numerous comparative genomic approaches have been developed to predict deleterious variants, but the approaches are nearly always assessed based on their ability to identify known disease-causing mutations in humans. Determining the accuracy of deleterious variant predictions in nonhuman species is important to understanding evolution, domestication, and potentially to improving crop quality and yield. To examine our ability to predict deleterious variants in plants we generated a curated database of 2,910 Arabidopsis thaliana mutants with known phenotypes. We evaluated seven approaches and found that while all performed well, their relative ranking differed from prior benchmarks in humans. We conclude that deleterious mutations can be reliably predicted in A. thaliana and likely other plant species, but that the relative performance of various approaches does not necessarily translate from one species to another.
Genomic Structural Variations Within Five Continental Populations of Drosophila melanogaster
Authors: Long Evan , Evans Carrie , Chaston John , Udall Joshua A 
Published: October 2018

Abstract
Chromosomal structural variations (SV) including insertions, deletions, inversions, and translocations occur within the genome and can have a significant effect on organismal phenotype. Some of these effects are caused by structural variations containing genes. Large structural variations represent a significant amount of the genetic diversity within a population. We used a global sampling of Drosophila melanogaster (Ithaca, Zimbabwe, Beijing, Tasmania, and Netherlands) to represent diverse populations within the species. We used long-read sequencing and optical mapping technologies to identify SVs in these genomes. Among the five lines examined, we found an average of 2,928 structural variants within these genomes. These structural variations varied greatly in size and location, included many exonic regions, and could impact adaptation and genomic evolution.
In situ tests for settlement design of compacted sand
Authors: Massarsch Karl Rainer , Fellenius Bengt H. 
Published: October 2018

The reliability of settlement analyses depends on the selection of realistic input parameters. The tangent modulus method is proposed for the settlement analysis of uncompacted and compacted sand. The tangent modulus can be estimated based on the appropriate modulus number and corresponding stress exponents. Four concepts are presented, based on whether the modulus number is estimated from laboratory tests, empirical values or in situ tests (cone penetration tests and flat dilatometer tests). From the increase in horizontal stress following compaction, it is possible to estimate the overconsolidation ratio. A case history is presented to illustrate application of the proposed concepts.
Dickkopf-3 (DKK3) in Urine Identifies Patients with Short-Term Risk of eGFR Loss
Authors: Zewinger Stephen , Rauen Thomas , Rudnicki Michael , Federico Giuseppina , Wagner Martina , Triem Sarah , Schunk Stefan J. , Petrakis Ioannis , Schmit David , Wagenpfeil Stefan , Heine Gunnar H. , Mayer Gert , Floege Jürgen , Fliser Danilo , Gröne Hermann-Josef , Speer Thimoteus 
Published: October 2018

Background
The individual course of CKD may vary, and improved methods for identifying which patients will experience short-term eGFR loss are needed. Assessing urinary Dickkopf-3 (DKK3), a stress-induced tubular epithelia–derived profibrotic glycoprotein, may provide information about ongoing tubulointerstitial fibrosis and short-term eGFR loss.

Methods
To investigate urinary DKK3’s potential as a biomarker of short-term eGFR loss (over 12 months), we prospectively assessed eGFR and urinary DKK3 levels in patients with CKD of various etiologies at baseline and annual follow-ups. We also measured urinary DKK3 in a general population sample and patients with diagnostic kidney biopsies or IgA nephropathy under treatment.

Results
Median urinary DKK3-to-creatinine concentration at baseline was significantly higher in patients with CKD than the general population sample (431 versus 33 pg/mg). In the CKD cohort, having a urinary DKK3-to-creatinine level >4000 pg/mg was independently and significantly associated after multiple adjustments with mean annual decline in eGFR of 7.6% over 12 months. Urinary DKK3 significantly improved prediction of kidney function decline compared with eGFR or albuminuria alone. Urinary DKK3-to-creatinine levels were related to the extent of tubulointerstitial fibrosis in kidney biopsies. In patients with IgA nephropathy, a rise in urinary DKK3 was associated with significant eGFR decline within 6 months, whereas stable or decreasing urinary DKK3 indicated a more favorable course.

Conclusions
Urinary DKK3 levels identify patients at high risk for eGFR decline over the next 12 months regardless of the cause of kidney injury and beyond established biomarkers, potentially providing a tool to monitor CKD progression and assess effects of interventions.
A Sequence Bounded Above by the Lucas Numbers
Authors: Aydoğdu Ali , Özkan Engin , Göçer Aykut 
Published: October 2018

In this work, we consider the sequence whose nth term is
the number of h-vectors of length n. The set of integer vectors E(n) is
introduced. For, n &gt;=2, the cardinality of E(n) is the nth Lucas
number Ln is
showed. The relation between the set of h-vectors L(n) and the
set of integer vectors E(n) is given.
Asymptotically Lacunary I-Invariant Statistical Equivalence of Sequences of Sets Defined By A Modulus Function
Authors: Dundar Erdinç , P. Akın Nimet , Ulusu Uğur 
Published: October 2018

In
this paper, we introduce the concepts of strongly asymptotically lacunary I-invariant equivalence, f-asymptotically
lacunary I-invariant equivalence, strongly f-asymptotically lacunary I-invariant equivalence and asymptotically lacunary I-invariant statistical equivalence for sequences of
sets. Also, we investigate some relationships among these concepts.
NİF OLYMPOS DAĞI ANTİK DÖNEM İNSANLARININ SAĞLIK SORUNLARI
Authors: YAVUZ Alper Yener , SEVİM EROL Ayla , ONUR İbrahim Semih 
Published: October 2018

Nif Olympos Dağı Kazı ve Araştırma
projesi, konum olarak İzmir ili, Kemalpaşa, Torbalı, Buca ilçelerinin ortak
sınırlarındadır. İzmir (Smyrna) Körfezi’nin doğusunda yer alır. Kuzeyinde
Kemalpaşa (Nif / Kryos Çayı) Ovası ve Manisa (Sipylos) Dağı; doğusunda Smyrna-
Sardeis yolunu Küçük Menderes (Kaystros) Vadisi’ne bağlayan Karabel Geçidi;
güneyinde Torbalı Ovası yer alır (Tulunay 2006).

Proje kapsamında 4 farklı alanda kazı
çalışmaları yapılmaktadır. Bu 4 farklı kazı alanının dönemleri de birbirinden
farklıdır. Dönem gözetmeksizin yapılan kazı çalışmalarından ele geçen
iskeletler değerlendirildiğinde toplamda 97 birey tespit edilmiştir. Ayrıca her bir alanda kendi içerisinde de demografi
çalışması yapılmıştır. Tespit edilen bireylerin 50’si erkek, 17 tanesi kadın,
10 tanesi çocuk, 4 tanesi bebektir. 16 bireyin ise cinsiyeti belirlenememiştir.
Nif Olympos Dağı Kazı ve Araştırma Projesi iskeletlerinde patolojik olarak da
birçok bulguya rastlanılmıştır. Özellikle bu bulgular içinde trepanasyonun
olması oldukça önemlidir. Nif Olympos Dağı Kazı ve Araştırma Projesi’nde ele
geçen trepanasyon örneği hem teknik olarak hem de uygulama bölgesi olarak
Anadolu örneklerinden oldukça farklıdır.
Mandibular asymmetry in Angle malocclusion samples
Authors: TERCANLI ALKIŞ Hümeyra , BİLGE Osman Murat 
Published: October 2018

Purpose:
The purpose of this study was to investigate the effect of different types of
occlusion on mandibular asymmetry by using panoramic radiography in various
anatomical points.Materials and Methods:
This retrospective study included 100 patients whose panoramic images and
malocclusions were registered in a patient database. Asymmetry indices were
evaluated according to the Habets asymmetry index formula using linear and
angular measurements of images. The effects of malocclusions, age and gender on
the asymmetry indices were investigated and ˂0.05 p value was considered
significant Results:
Of the total 100 patients 51 (51%) were female and 49 (49%) were male. Associations
were found between gender and the right corpus length, right and left gonial
angle values, and between malocclusion and the right condylar height and right
and left corpus length.

Conclusion:
Although values of some parameters varied with gender and malocclusion, there
was no statistically significant relationship found between age, gender and
malocclusion and asymmetry index values for any parameter.
Стыд и моральная ответственность организованных коллективов
Authors: Прокофьев Андрей Вячеславович 
Published: October 2018

<p>Цель данной статьи — выявить место моральной эмоции стыда в механизмах моральной ответственности организованных коллективов (бизнес-корпораций, самоуправляющихся ассоциаций, государственных организаций). В своих ретроспективных проявлениях моральная ответственность тесно связана с осуждением нарушителя нравственной нормы. Нарушитель подлежит внешнему осуждению, но и от него самого также ожидается осуждение совершенного им поступка. Признаком подлинности самоосуждения принято считать наличие негативных эмоций самооценки, таких как вина и стыд.</p><p>В рамках данного исследования используется такое понимание стыда, при котором он является негативной эмоцией, возникающей на фоне действительной или потенциальной осведомленности других людей о совершенном нарушении и сосредоточенной на проявившемся в поступке моральном качестве личности нарушителя. Вина, в свою очередь, не обусловлена внешними факторами и сосредоточена на моральном качестве самого действия и его последствий. Организованные коллективы можно рассматривать в качестве деятелей, способных нести моральную ответственность в силу наличия у них внутренних структур принятия решений (термин П. Френча). К примеру, решения бизнес-корпорации можно отграничить от решений ее менеджеров, не выражающих намерений организованного коллектива. Существенным затруднением для признания таких коллективов ответственными моральными деятелями является отсутствие у них аффективной составляющей поведения: тот, кто не способен осуждать себя в эмоциональных формах, не подлежит моральному осуждению. Однако более глубокий анализ свойств организованного коллектива позволяет утверждать, что он обладает функциональными аналогами или субститутами эмоций самооценки. При этом они гораздо больше похожи на индивидуальный стыд, чем на индивидуальную вину. Организованный коллектив способен как выражать стыд, так и опасаться стыда. Эта его особенность должна найти отражение в системе наказания бизнес-корпораций. В их отношении уместно использовать так называемые пристыжающие санкции, наносящие удар по корпоративной репутации.</p>