bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relación entre trastorno afectivo bipolar, depresión, ansiedad, estrés y valores de presión arterial en población de la clínica San Jjuan de Dios, Manizales, Colombia, 2014
Authors: Alfaro Moreno Lizeth Jimena , Álvarez Giraldo Carolina , Castaño Castrillón José Jaime , Medina Gil Manuelita , Montoya Jiménez María Paula , Ortega Borja Natalia , Valencia Franco Germán Anfrés 
Published: May 2019

Objetivo: Identificar, en población psiquiátrica diagnosticada, emociones específicas como estrés, depresión, ansiedad, trastorno afectivo bipolar y su asociación con niveles de presión arterial. Materiales y métodos: Es un estudio de tipo correlacional que incluye 150 pacientes hospitalizados en la clínica San Juan de Dios de Manizales (Caldas, Colombia), con diagnóstico psiquiátrico (depresión, ansiedad, trastorno bipolar, estrés). La recolección de la información se realiza mediante la revisión de historias clínicas en una población mayor de 18 años y se analizan diferentes variables (demográficas, personales y de patología mental). Resultados: 59,3% de género femenino, edad promedio de 45,7±15,78 años, 27,3% presentan hipertensión, 2% ansiedad, 20% depresión, 5,3% estrés, 74% trastorno bipolar. La prevalencia de hipertensión grado 1 y normal alta en pacientes con trastorno bipolar fue mayor que en la población general (15,3% y 60,4% frente a 5,1%, 48,7%) en Manizales. Se encuentra relación significativa entre trastorno bipolar e hipertensión (p=0,022) y se evidencia una dependencia significativa entre presión arterial diastólica y trastorno afectivo bipolar (p=0,026). Los pacientes con trastono bipolar tienen mayor incidencia de HTA, comparado con la población sin el trastorno. Conclusiones: El presente estudio indica que la enfermedad mental por sí sola, no predispone a la hipertensión, así como en pacientes con diagnósticos de ansiedad, depresión, estrés. A diferencia de la asociación positiva encontrada en pacientes con trastorbo bipolar.
Actitudes hacia el ejercicio físico y práctica de actividad física en profesionales de la salud: estudio de corte transversal, 2015.
Authors: Sánchez Delgado Juan Carlos , Escobar Pinzón Soel Gineth , Vega Camacho José David , Porras Solano Anghelo Javier , Angarita Fonseca Adriana 
Published: May 2019

Objetivo: Describir las actitudes hacia el ejercicio físico y el cumplimiento de las recomendaciones de Actividad Física de los profesionales de la salud pertenecientes a una Institución Prestadora de Salud (IPS) de Bucaramanga. Métodos: estudio descriptivo exploratorio, realizado en 33 sujetos (36,06 ± 7,77 años; 72,73% mujeres) a los que se les aplicó un cuestionario que incluía 7 preguntas tipo Likert, dos de selección múltiple con única respuesta, y la versión corta del IPAQ. Resultados: La mayoría reporta tener una buena actitud hacia el ejercicio físico y el 42,4% cumple las recomendaciones de actividad física según la OMS. En el análisis exploratorio, la actitud asociada al cumplimiento de recomendaciones de actividad física fue: estoy conforme con la formación profesional en ejercicio físico que he recibido. Aquellos que reportaron estar en desacuerdo, muy en desacuerdo, ni en acuerdo ni en desacuerdo cumplían en menor proporción estas recomendaciones (p=0,039). Conclusiones: todos los evaluados consideran importante tener buenos hábitos de actividad física, prescribir ejercicio y además recomiendan AF para la prevención o manejo de enfermedades. Por otra parte se observó, que el no estar conforme con la formación académica recibida en ejercicio físico puede ser una barrera para el cumplimiento de las recomendaciones de actividad física
Uso de internet y su relación con la salud en estudiantes universitarios de la ciudad de Manizales (Caldas-Colombia), 2015-2016
Authors: Cañon Buitrago Sandra Constanza , Castaño Castrillón José Jaime , Hoyos Monroy Deissy Carolina , Jaramillo Hernández Juan Camilo , Leal Ríos Daniel Roberto , Rincón Viveros Resban , Sánchez Preciado Edinson Andrés , Urueña Calderón Linda Stephany 
Published: May 2019

Objetivo: la red internet es una de las herramientas más usadas por las personas, tanto que ha llegado incluso a presentarse uso problemático de este y por lo tanto a la aparición de problemas relacionados con su ocupación sin control. Se pretende estudiar el uso de Internet en estudiantes universitarios de 5 universidades del departamento de Caldas (Colombia), y su relación con factores personales que pueden verse afectados por este. Materiales y métodos: se tomó una población de 640 estudiantes de 5 universidades. Se realizaron encuestas aplicando varios instrumentos para medir las variables demográficas, funcionalidad familiar, trastornos de alimentación y sueño, déficit de atención e hiperactividad, ansiedad y depresión y su relación con la existencia de adicción a internet. Resultados: el 77,3% de los estudiantes participantes presentan algún grado de adicción a internet, el celular es el de mayor empleo con 65,6% para acceder, el principal motivo fueron las redes sociales 76,4%. Se encontró que la adicción a internet está relacionada con las siguientes variables somnolencia (p=0,000), trastornos de la conducta alimentaria (p=0,012), depresión (p=0,000), estrés de examen (p=0,000), funcionalidad familiar (0,000), promedio de notas (p=0,001), género (0,000), diversos síntomas como molestias en los dedos (p=0,000), molestias en el codo (p=0,000) y otros, hiperactividad (p=0,000) e inatención (p=0,000). Conclusiones: similar a lo que sucede en otras poblaciones de estudiantes, en esta se presenta una alta proporción de adicción a internet, la cual está relacionada con múltiples aspectos de la vida cotidiana del estudiante.
Coherencia cortical interhemisférica de ninãs en el periodos pre y pos menarquia.
Authors: Rocha Letícia Ecard , Gonçalves Fabre Daniele , Terra Siqueira Patrícia , Fernandes Filho José , Roquetti Fernandes Paula 
Published: May 2019

Objetivo: el presente estudio tuvo como objetivo observar la coherencia cortical interhemisférica en niñas el períodos pre y pos menarquia. Materiales y métodos: una muestra de 45 niñas de 10 a 15 años fue compuesta y dividida en dos grupos: pre menarquia (G1) y pos menarquia (G2) compuestos por 21 y 24 niñas, respectivamente. Las participantes en el estudio se sometieron a captar la señal electroencefalográfico en reposo. Después de la recogida de datos, fue realizado el cálculo de la variable dependiente extraída del eletroencefalograma quantitativo. Para el análisis del índice de coherencia se rotaron las pruebas de Mann-Whitney para cada par de electrodos (frontales: F3-F4; central C3-C4 y parietal: P3-P4), específicamente en la banda de frecuencia beta (13-35 Hz). Resultados: fueron observadas diferencias estadísticamente significativas en las tres áreas corticales (F3-F4: p = 0,001; C3-C4: p = 0,002 y P3-P4: p = 0,003). Específicamente, el grupo pos menarquia mostraron valores de coherencia significativamente más altos en los tres pares de electrodos analizados, o sea, en las tres regiones corticales; en comparación con el grupo pre menarquia. Esto significa decir que cuanto mayor el grado de maduración del grupo, mayores son las posibilidades de los valores de coherencia interhemisférica presentarse más elevados. Conclusiones: se observó que, con relación a las características electroencefalográficas, los grupos se mostrarón distintos, siendo mayor la atictividad cerebral relacionada a la coherencia interhemisférica del grupo pos menarquia.
Absceso de pared abdominal por tumor maligno de colon transverso.
Authors: Morales Polanco Sergio , Díaz Rosales Juan de Dios , Arenas Valles Jorge 
Published: May 2019

Introducción: El cáncer de colon es uno de los tumores digestivos más frecuentes y mortales. Sus complicaciones pueden ser variadas y en ocasiones tener presentaciones raras o poco frecuentes. Se presenta el caso de un paciente con un absceso de pared abdominal secundario a la perforación de un tumor en colon transverso. Caso clínico: Masculino de 56 años, en estado séptico y una masa en cuadrante superior izquierdo. Se sometió a laparotomía exploradora y se encontró un tumor de colon transverso que penetraba hacía la pared abdominal e invadía el yeyuno proximal y epiplón mayor. Se realizó la resección del tumor, colon transverso y epiplón mayor, dejando márgenes positivos en yeyuno. Discusión y conclusiones: Aunque no existe consenso acerca de esta complicación, los casos reportados en la literatura orientan acerca del abordaje diagnóstico y terapéutico en caso de enfrentar esta complicación. Sin embargo, el escenario en un hospital de segundo nivel de atención se deben adecuar los recursos disponibles y la terapéutica a emplear, siempre pensando en ofrecer el mejor tratamiento posible para el paciente.
ВТІЛЕННЯ КОНЦЕПТІВ ГЕЙМ-ДИЗАЙНУ ПРИ РОЗРОБЛЕННІ ІГРОВОГО ПРОЕКТУ «МАВКА» В УМОВАХ ЗАПИТІВ СУЧАСНОСТІ
Authors: Колісник О. В. , Гула Є. П. 
Published: May 2019

The purpose of the study is to identify the features of creating a competitive game-design and its implementation in the game project "Mavka", adapted to the modern needs of the target audience, both from the standpoint of artistic and expressive means and technological limitations, and stylistic features caused by the genre of the project. Methodological basis of the study is a comparative method of analysis of successfully implemented game projects, which allowed to reveal the essential characteristics of the latter. The analysis of the functioning of avatars in game design was made possible by the modeling method. Also, the method of system analysis of publications and sociological methods were used, which allow to determine the basic patterns of the development of game content design, its direct influence on the perception of the target audience of the project, the needs and expectations of society. The results of this scientific study have a theoretical significance, which is to determine the influence of the characteristics of the character, his appearance, biography, attributes and game behavior to increase the degree of empathy experienced by the user in relation to the game character within the gameplay, given the modern socio-cultural realities reflected in the game. Also, the article studies the artistic and aesthetic qualities of the project and its general attractiveness for the target audience. The analysis of the main principles of the creation and development of game characters has been carried out, and the main points have been defined in terms of players' needs and game-design abilities. The results provide an opportunity for a deeper understanding of the use of these developments to optimize the process of finding appropriate artistic and expressive means at the development stage of the visual component of the game project, the development domestic video games, as well as mobile games, whose aesthetic, technological and consumer properties will meet the expectations of the target audience and provide decent competition to foreign counterparts.
PILOT VALIDATION OF EARLY PREDICTORS FOR NEONATAL SEPSIS
Authors: Gizatullin R. Kh. , Mironov P. I. , Lekmanov A. U. 
Published: May 2019

Purpose: pilot development of the system estimating the risk for sepsis in newborns and determining its discrimination power.Methods. Design: a retrospective observational single-center study. 124 newborns with sepsis are included; 34 of them died. Kullback’s measure was used to estimate the information value of the examined clinical and laboratory variables. Disease outcome (whether survived or dead) was the response function. The discrimination power was determined using ROC-analysis.Results. The information value of the examined clinical and laboratory variables in the newborns was analyzed as related to the risk for sepsis. Early neonatal sepsis predictors include platelet count, total protein content, body mass and neutrophil count. Discrimination power of the mentioned predictors was calculated.Result. Determination of the risk for sepsis in a newborn based on the estimation of platelet count, neutrophil count, total protein and body mass is of moderate value.
Considering Students’ Prior Knowledge in Culture-based Contextual Learning Media Application: How Effective It is to Support Students’ Mathematics Learning Outcome
Authors: Wijayanto Zainnur , Retnaningsih Rahayu 
Published: May 2019

The present study aims to describe the effectiveness of culture-based contextual mathematics learning media by considering students’ prior knowledge. This is a quasi-experimental study that employed pretest-postest non-equivalent group design. Eight graders of a Junior High School (JHS) in Yogyakarta were involved as experimental and control groups. The data were obtained through a test to find out the students' mathematics learning achievements, while the data analysis technique used is the analysis of two-way variance with unequal cells. The results indicate that by considering the students’ previous knowledge, the culture-based contextual mathematics learning media is more effective than the conventional ones.
“Gettolaşma” Söylemi Bağlamında Sosyo-mekânsal Sürgün Yerleri
Authors: AKGÜN GÜLTEKİN Asiye 
Published: May 2019

Ekonomik, kültürel,
sosyal ve politik süreçlerin kent mekânındaki izdüşümü olarak mekânsal dışlama
ve kentsel eşitsizliklerin ortaya çıktığı görülmektedir. Bu bağlamda kent
peyzajında ortaya çıkan kümelenmeler, 1970 sonrası gelişmiş ülkelerde görülen
kentsel hareketler ve aktörler arasındaki ilişkilerin kentsel eşitsizlikleri nasıl
tetiklediği sorusu önem kazanmaktadır. Kentsel sosyo-mekânsal kapanma ya da
inziva biçimleri olarak getto ve banliyölerin yapısal ve işlevsel
farklılıklarının altının çizildiği; bu tiplerin aynılaştırılmaya çalışılan
söylemlerinin arka planında neler olacağı yönündeki tartışmayı içeren çalışmada
bir dizi politik ve medya söylemlerine yer verildi. Sömürge sonrası dünya
kentlerinde ileri marjinalliğin mekânları olarak genel kabul gören, şiddet ile
yaftalanan, heterojen demografinin emek piyasasından dışlandığı, sistemle sorunlu
ilişkisinin tanımlandığı sürgün yerleri kentsel bir oluşum olarak apaçık
karşımızda durmaktadır. Gettolaşan Avrupa söylemlerine, Wacquant’ın
değerlendirmeleri paralelinde bakan bu yazının temel endişesi; mekânın sosyal
boyutu ve topluluk üzerindeki etkilerini anlamaya yöneliktir. Getto,
hipergetto, antigetto kavramları arasındaki farkların neler olduğuna ilişkin
tartışma La Haine filmi okuması üzerinden yürütüldü. Bu metnin ortaya
çıkışındaki süreçte Fransa’da yaşanan “sarı yelek” protestolarının ekonomik,
kültürel ve sosyo-mekânsal bagajlarını deşmek düşüncesi yer alır. Mekânsal dışlamanın etno-ırksal, sınıfsal
formlarının arkasındaki ilişkiler ağının haritasının çıkartılması; bu çalışmanın
hedefini oluşturmaktadır.
Correlation of QRS duration with intraventricular mechanical dyssynchrony on tissue Doppler imaging in heart failure
Authors: Shrestha Sanjaya Kumar 
Published: May 2019

Introductions: Wide QRS complex with left bundle branch block morphology is one of the three criteria for cardiac resynchronization therapy (CRT) in heart failure (HF) patients who do not improve on medical management. Approximately 30% of patients do not respond to CRT. This study investigates to find out to what extent the wide QRS duration correlates with the intraventricular mechanical dyssynchrony (IVMD) as measured by Tissue Doppler Imaging (TDI) echocardiography.
Methods: The HF patients of dilated or ischemic cardiomyopathy with ejection fraction £35% admitted in the medical ward of Patan Hospital, Nepal from March to August 2017 were enrolled in the study. They were divided into two groups, narrow QRS duration of <120ms (Gr1) and wide QRS duration of ³120ms (Gr2). TDI was performed to measure time to peak systolic velocity of the left ventricular walls. The IVMD, defined as 60 ms (millisecond) or greater difference in time to peak velocity between any two points of the left ventricular walls, was compared in both groups.
Results: There were 26 patients, 18 in group-1, and eight in Gr2.In Gr1, IVMD was observed 13/18 (72%) patients and in group-2 in 7/8 (87%) patients, (χ2 = 0.70, p = 0.403). There was no significant difference of IVMD between Gr1 and Gr2 (73±36ms vs 97±38ms, t = 1.54, p = 0.136).
Conclusions: Assessment of intraventricular mechanical dyssynchrony (IVMD) by Tissue Doppler Imaging (TDI) is probably superior to QRS duration in heart failure patients.
Clinicopathological study of breast diseases: A hospital-based study
Authors: Chavan Ramesh , Prasad Anil 
Published: May 2019

Background: Breast diseases are more common in women than men. Breasts undergo perpetual physical and physiological transition from puberty till death, which are related to menstruation, pregnancy, and menopause. The aim of this was to classify different types of the breast lesions, and conduct its clinicopathological study.
Materials and Methods: Breast lesion tissue specimens were collected either as needle biopsy, lumpectomy, or mastectomy. For specimens fixation, 10% formal saline was used. Tissue was processed into paraffin blocks and stained using hematoxylin and eosin. Data were entered into Microsoft Excel spreadsheets and analyzed using percentages.
Results: Out of 150 patients, 97.3% were female and 2.7% were male. Nonneoplastic lesions and neoplastic lesions accounted for 11% and 89% of the cases in patients, respectively. Among the nonneoplastic lesions, chronic mastitis (47%) was most common. Fibroadenoma (76%) and invasive ductal carcinoma (91%) was the highest encountered benign and malignant neoplasm, respectively. Maximum (43%) of benign neoplasm incidence was encountered in the age-group 20–30 years; whereas in malignant neoplasm, it was 40–50 years (38%). Out of 150 patients, 55% were diagnosed with Nottingham grading system grade 2 of breast cancer.
Conclusions: Occurrence of neoplastic lesions in the breasts is comparatively higher than nonneoplastic lesions. Differentiating between benign and malignant lesions would be useful in the management and treatment of patients.
A comparison of two techniques of cell block preparation
Authors: Kasichhwa Anita , Shrivastav Shreya , Agrawal Ayushi 
Published: May 2019

Background: Cell block technique is a method of preparing cytological material so that it can be processed, sectioned, stained, and viewed as a histology section. The study compared two methods of cell block preparation, plasma-thromboplastin method and collodion bag technique of cell block preparation.
Materials and Methods: Samples were randomly processed by plasma-thromboplastin technique or by collodion bag technique. Hematoxylin/Eosin stained cell block sections were examined and scored scaling from 1 to 3 for cellularity, clarity, nuclear features, cytoplasm, use of ancillary test and recovery of cell-cluster and fragments. Mann-Whitney U test was used for comparing two methods and establishing statistical significance.
Results: The median cellularity score was 2.0 for plasma-thromboplastin and 1.0 for collodion bag. The median morphological preservation score and use of ancillary test score were 2.0 for both of the method while median score for recovery of cell cluster and fragments was 2.0 for collodion bag and 1.0 for plasma-thromboplastin. Statistically, both of the methods had similar results in cell block quality.
The median total score for plasma-thromboplastin and collodion bag were 10.0 and 11.0 respectively. Diagnostic cell blocks were obtained in 46.51% of cell block by plasma-thromboplastin method and 60.52% of cell block by collodion bag method improving the diagnosis over conventional smear in 76.74% and 81.57% respectively.
Conclusions: Cell block by plasma-thromboplastin and collodion bag method are cost effective, useful adjunct to FNA for diagnosis of mass lesion. Both techniques has no significant difference in quality of cell block produced.
Cytohistological correlation of conventional Papanicolaou smears in cervical neoplasia at a tertiary care hospital of Nepal
Authors: Poudel Anuj , Dahal Prahar 
Published: May 2019

Background: Conventional Cervical Cytology is the most widely used cervical cancer screening test. The incidence of cervical carcinoma is incredibly high in developing countries due to lack of proper knowledge. The extensive use of cervical screening with Papanicolau smears had considerably increased the detection of precancerous and cancerous lesion of uterine cervix. Study was conducted to evaluate cytohistological correlation and to calculate concordance and discordance of Pap smear in detection of precancerous and cancerous lesions of uterine cervix.
Materials and Methods: A total of 54 samples reported in Pap smear as cervical intraepithelial lesions and suspicious for invasive malignancies were selected and correlated with corresponding histopathological findings. It was an observational study done for a period of 18 months from November 2016 to May 2018 at UCMS-TH. All the statistical evaluation was done by using SPSS version 20.
Results: During the study period 54 cases were evaluated. Atypical Squamous Cell of Undetermined Significance was the common abnormal findings in the Pap smear with frequency of 26 (48.1%). Out of total 54 cases of Pap smears, 30 (55.55%) were concordant while discrepancies occurred in 24(44.44%) cases with cervical biopsy.
Conclusions: The study revealed a good correlation between cervical cytology and cervical biopsy. We also concluded that conventional Pap smear is a cost effective test for the early detection of precancerous and cancerous cervical lesions.
Study of serum lipase level in pregnant woman presenting with nausea and vomiting
Authors: Dhungana Arun , Gautam Pratigyan , Manandhar Rosina , Karki Chanda 
Published: May 2019

Background: Hyperemesis gravidarum is a complex condition characterized by excessive nausea and vomiting during pregnancy. It presents with various symptoms which include disturbed nutrition, electrolyte imbalance, ketosis and extreme weight loss. The objective of this study is to compare serum lipase, amylase and glucose in Hyperemesis gravidarum with non-pregnant women.
Materials and methods: A total of 100 subjects among which 50 were nonpregnant women as controls and 50 were women with hyperemesis gravidarum as cases were enrolled in the study. Serum lipase, amylase and glucose levels were estimated in all the subjects.
Results: The levels of mean serum lipase were lesser in cases (23.55 ± 4.91U/L) compared to that in controls (25.45 ± 5.97U/L) with p=0.086. However, the levels of mean serum amylase were higher in cases (76.40 ± 33.86 U/L) compared to that in controls (69.66 ± 16.45U/L) with p= 0.210. Serum amylase activity was raised in 8% of the patients whereas the activity of pancreatic lipase was within normal range. Serum glucose levels were lower in cases (84.72 ± 11.28 mg/dl) than that in controls (87.04 ± 10.65 mg/dl) with p=0.293.
Conclusions: From this study we conclude that lipase activity was statistically insignificant in hyperemesis gravidarum. Therefore, pancreatic activities were less affected by hyperemesis gravidarum. So, this condition needs further exploration regarding biochemical basis to minimize the risk associated with it.
Pseudomembranous colitis
Authors: Pyakurel Devish 
Published: May 2019

Pseudomembranous colitis is an inflammatory condition of the colon that is most often a manifestation of Clostridium difficile infection. If laboratory testing and endoscopic finding for Clostridium difficile infection is negative, then other less common etiologies should be sought for to identify the correct diagnosis. Ischemic colitis, inflammatory bowel disease, medications, chemicals, vasculitis, and multiple infectious pathogens are responsible for non-clostridium difficile Pseudomembranous colitis. Exposure history, chronic medical problems and a current medication list will aid in narrowing the differential diagnosis. Histology varies significantly with underlying etiology and can establish the diagnosis. Treatment is specific to the underlying etiology. The purpose of this review article is to aware clinicians and other healthcare professionals about various etiologies of pseudo membranous colitis along with its histological finding and treatment.