bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reusability and adaptability of interactive resources in Web-based educational systems
Authors: Saddik Abdulmotaleb El , Fischer Stephan , Steinmetz Ralf 
Published: July 2002

The production of interactive multimedia content is in most cases an expensive task in terms of time and cost. Hence, optimizing production by exploiting the reusability of interactive multimedia elements is mandatory. Reusability can be triggered by a combination of resuable multimedia components and the appropriate use of metadata to control the components as well as their combination.
In this article, we discuss the reusability aspects of interactive multimedia content in web-based learning systems. In contrast to existing approaches, we extend a component-based architecture to build interactive multimedia visualization units with the use of metadata for reusability and customizability.
In the three-tier model, the lowest layer of the paradigm corresponds to the programmer (code reusability). The user interface of an educational visualization is located at the top layer where the interaction with the end-user (student) takes place. The educator is located between the top and the bottom layers. This medium layer allows adapting interactive multimedia content according to the needs of the user, applying a predefined set of metadata. The teacher can both adjust the level of explanation and the level of interactivity of an animation, and influence the presentation and the results of the algorithms being illustrated (program reusability). After a theoretical overview, we explain our architecture by giving an example of an application.
Optimal VLSI circuits for sorting
Authors: Cole Richard , Siegel Alan 
Published: July 2002

This work describes a large number of constructions for sortingNintegers in the range [0,M- 1], forN≤M≤N2, for the standard VLSI bit model. Among other results, we attain:VLSI sorter constructions that are within a constant factor of optimal size, for allMand almost all running timesT.a fundamentally new merging network for sorting numbers in a bit model.new organizational approaches for optimal tuning of merging networks and the proper management of data flow.
AGM: a dataflow database machine
Authors: Bic Lubomir , Hartmann Robert L. 
Published: July 2002

In recent years, a number of database machines consisting of large numbers of parallel processing elements have been proposed. Unfortunately, there are two main limitations in database processing that prevent a high degree of parallelism; these are the available I/O bandwidth of the underlying storage devices and the concurrency control mechanisms necessary to guarantee data integrity. The main problem with conventional approaches is the lack of a computational model capable of utilizing the potential of any significant number of processing elements and storage devices and, at the same time, preserving the integrity of the database.
This paper presents a database model and its associated architecture, which is based on the principles of data-driven computation. According to this model, the database is represented as a network in which each node is conceptually an independent, asynchronous processing element, capable of communicating with other nodes by exchanging messages along the network arcs. To answer a query, one or more such messages, called tokens, are created and injected into the network. These then propagate asynchronously through the network in search of results satisfying the given query.
The asynchronous nature of processing permits the model to be mapped onto a computer architecture consisting of large numbers of independent disk units and processing elements. This increases both the available I/O bandwidth as well as the processing potential of the machine. At the same time, new concurrency control and error recovery mechanisms are necessary to cope with the resulting parallelism.
Concurrency and availability as dual properties of replicated atomic data
Authors: Herlihy M. 
Published: July 2002

A replicated data object is a typed object that is stored redundantly at multiple locations in a distributed system. Each of the object's operations has a set of quorums, which are sets of sites whose cooperation is needed to execute that operation. A quorum assignment associates each operation with its set of quorums. An operation's quorums determine its availability, and the constraints governing an object's quorum assignments determine the range of availability properties realizable by replication.In this paper, the restrictions on quorum assignment imposed by three kinds of atomicity mechanisms found in the literature are analyzed: (1) serial schemes, in which replication and atomicity are implemented independently at different levels in the system, (2) static schemes, in which the transaction serialization order is predetermined, and (3) hybrid schemes in which the serialization order emerges dynamically.The following results are derived: (1) Although serial schemes place the strongest restrictions on concurrency, they place the weakest restrictions on availability. (2) Although hybrid and static mechanisms place incomparable restrictions on concurrency, hybrid mechanisms place weaker restrictions on availability. (3) Bounding the maximum depth of transaction nesting strengthens restrictions on concurrency for all classes, but weakens restrictions on availability for hybrid schemes only. Concurrency and availability are best considered as dual properties: A complete analysis of an atomicity mechanism should take both into account.
Computer-aided modeling and planning (CAMP)
Authors: Sagie Ike 
Published: July 2002

Many planning methods are based on mathematical modeling. A multitude of computer aids covers different facets of the planning activity: data management, linear programming, statistical analysis, graphics, and word processing. However, the diversity and complexity of the available software inhibit the widespread use of computers for planning.
The integrated Computer-Aided Modeling and Planning (CAMP) system offers a simple and coherent tool for the planner. A Data Definition Language provides the means for building data banks; a Model Definition Language provides the means for defining mathematical models featuring abstract linear programming, advanced array arithmetics, and assertions; a Picture Definition Language facilitates formation of tables and diagrams; a Text Definition Language combines word processing with illustrations of modeling results. The man-machine interface is based on interactive panels for controlling the planning process and on a command language for analyzing modeling results. A multilingual capability allows selection of the national language for interfacing with the system.
The architecture of CAMP is presented, and its design, implementation, and use in regional planning are discussed.
Binding and Normalization of Binary Sparse Distributed Representations by Context-Dependent Thinning
Authors: Rachkovskij Dmitri A. , Kussul Ernst M. 
Published: July 2002

Distributed representations were often criticized as inappropriate for encoding of data with a complex structure. However Plate's holographic reduced representations and Kanerva's binary spatter codes are recent schemes that allow on-the-fly encoding of nested compositional structures by real-valued or dense binary vectors of fixed dimensionality. In this article we consider procedures of the context-dependent thinning developed for representation of complex hierarchical items in the architecture of associative-projective neural networks. These procedures provide binding of items represented by sparse binary codevectors (with low probability of 1s). Such an encoding is biologically plausible and allows a high storage capacity of distributed associative memory where the codevectors may be stored. In contrast to known binding procedures, context-dependent thinning preserves the same low density (or sparseness) of the bound codevector for a varied number of component codevectors. Besides, a bound codevector is similar not only to another one with similar component codevectors (as in other schemes) but also to the component codevectors themselves. This allows the similarity of structures to be estimated by the overlap of their codevectors, without retrieval of the component codevectors. This also allows easy retrieval of the component codevectors. Examples of algorithmic and neural network implementations of the thinning procedures are considered. We also present representation examples for various types of nested structured data (propositions using role filler and predicate arguments schemes, trees, and directed acyclic graphs) using sparse codevectors of fixed dimension. Such representations may provide a fruitful alternative to the symbolic representations of traditional artificial intelligence as well as to the localist and microfeature-based connectionist representations.
THE INTERDICTION OF THE SPENDTHRIFT (AL-SAFĪH): A HUMAN RIGHTS DEBATE IN CLASSICAL FIQH
Authors: Arabi Oussama 
Published: July 2002

AbstractA semantic equivalence between the Qur'ānic terms safīh and mubadhdhir underlies classical Islamic law's interdiction (hajr) of the spendthrift. The Qur'ān, however, is not explicit in endorsing the semantic equivalence of these two terms. To bridge this semantic gap, Muslim jurists exploited an opposition in Arabic usage between safah and rushd, extending the meaning of safīh from "one who lacks judgment" to "one who squanders his wealth". Subsequently, the safīh became the object of disagreement among the Hanafī master jurists: Abū Hanīfa placed a greater value on the sane adult's legal autonomy than on the preservation of his wealth; Abū Yūsuf and al-Shaybānī (together with Mālik, al-Shāfi ī and the Hanbalīs) held for the restriction of the adult prodigal's legal capacity. Ibn Hazm revived Abū Hanīfa's position by undertaking a lexicographical critique of the metaphorical extension of the meaning of safīh and by upholding the Muslim ideal of modest living.
Aristotle on Improving One's Character
Authors: Muzio Gianluca Di 
Published: July 2002

AbstractContrary to what most interpreters hold, in the Nicomachean Ethics Aristotle is not committed to the view that people of established vicious character could never become good. The present paper proves this result (1) by giving a better reading of 1114 a 12-21, a passage which has traditionally been taken to assert that unjust and self-indulgent people are doomed to a lifetime of vice; (2) by showing that when Aristotle refers to self-indulgent people as "incurable", he does not mean that they could never change, but only that they could not change as a result of external influences such as persuasion or punishment; (3) by proving that although Aristotle regards the desires of vicious people as determined by their character, there is room within Aristotelian moral psychology for the possibility that people of corrupt character become motivated to begin a process of moral reform.
Video Dog Star: William Wegman, Aesthetic Agency, and the Animal in Experimental Video Art
Authors: McHugh Susan 
Published: July 2002

AbstractThe canine photographs, videos, and photographic narratives of artist William Wegman frame questions of animal aesthetic agency. Over the past 30 years, Wegman's dog images shift in form and content in ways that reflect the artist's increasing anxiety over his control of the art-making process once he becomes identified, in his own words, as "the dog photographer". Wegman's dog images claim unique cultural prominence, appearing regularly in fine art museums as well as on broadcast television. But, as Wegman comes to use these images to document his own transition from dog photographer to dog breeder, these texts also reflect increasing restrictions on what I term the "pack aesthetics," or collaborative production of art and artistic agency, that distinguish some of the early pieces. Accounting for the correlations between multiple and mongrel dogs in Wegman's experimental video work and exclusively Weimaraner-breed dogs with human bodies in his recent work in large-format Polaroid photography, this article explores how Wegman's work with his "video dog star," his first Weimaraner dog Man Ray, troubles the erasure of the animal in contemporary conceptions of artistic authority.
Genomic Imprinting and the Cognitive Architecture Mediating Human Culture
Authors: Brown William Michael 
Published: July 2002

AbstractGenomic imprinting may be implicated in the origin and maintenance of the cognitive architecture required for cultural transmission. Relatedness asymmetries are expected to lead to increases in the receptibility of matrilineally transmitted information. This may help explain why maternal genes contribute preferentially to the neocortex. That is, maternal genes could influence biases in the transmission and/or acquisition of information. This perspective is complementary to gene-culture coevolutionary approaches.
SOCIAL STATUS AND REPRODUCTIVE SUCCESS IN QUEENLESS ANT COLONIES
Authors: Trunzer  , Heinze  , Holldobler  
Published: July 2002

Abstract
Workers in queenless colonies of the ponerine ant Pachycondyla villosa establish linear or near-linear rank orders by antennation bouts and overt aggression. In these hierarchies, top-ranking individuals were reliably among the most productive egg-layers, but several lower ranking workers also laid considerable numbers of eggs. Though many of the subordinates' eggs were eaten by the-workers, we could show by multilocus DNA-fingerprinting that low-ranking individuals occasionally succeeded in producing adult males. However, the most dominant workers always had the highest reproductive success.
Isolation and localisation of an annexin gene (gp-nex) from the potato cyst nematode, Globodera pallida
Authors: Warry Andrew , Curtis Rosane , Porter Andrew , Fioretti Luca , Haydock Patrick 
Published: July 2002

AbstractA full length cDNA clone was isolated by screening a mixed stage Globodera pallida expression library using the monospecific polyclonal antibody IACR-PC320. Sequence comparison indicated that the predicted 332 amino acid protein encoded by the cDNA was a member of the annexin gene family named gp-nex and very similar to annexins found in other nematode species. Annexins are calcium-dependent phospholipid binding proteins characterised by four repeated domains approximately 70 amino acids in length. The predicted amino acid sequence of the protein did not contain an N-terminal secretion signal peptide; however, the protein was shown to be present in excretory/secretory products from G. pallida second stage juveniles treated with the neurotransmitter 5 methoxy-N, N dimethyl tryptamine. Gp-nex encodes a protein of 35 kDa and was immunolocalised in the amphids, genital primordium and in the constraining muscles above and below the metacorpus pump chamber of G. pallida second stage juveniles. It is also present in eggs and adult females of the two species of the potato cyst nematodes.
Identification and ecological characterisation of three entomopathogenic nematode-bacterium complexes from Turkey
Authors: Susurluk Alper , Wyss Urs , Ehlers Ralf-Udo , Strauch Olaf , Stackebrandt Erko , Dix Ilona 
Published: July 2002

AbstractTwo heterorhabditid nematode strains (TUR-H1 and TUR-H2), and their bacterial symbionts isolated from soil samples taken at the campus of the Agriculture Faculty of the University of Ankara, Turkey, were identified by molecular methods and by cross-breeding with Heterorhabditis bacteriophora. The bacterial symbionts shared >99% similarity in the 16S rDNA sequence with Photorhabdus luminescens subsp. laumondii. Results of the restriction fragment length analysis of the ITS region assigned both nematode strains to the species H. bacteriophora. Cross-breeding confirmed the species designation for strain TUR-H2. Crosses of TUR-H1 with a hybrid strain of H. bacteriophora or with TUR-H2 resulted in infertile offspring. Both strains reproduced in monoxenic cultures of the symbionts P.luminescens isolated from H. bacteriophora and H. megidis and the resulting dauer juveniles retained cells of the bacteria. Reproduction on the symbionts isolated from H. indica failed. Infectivity at variable soil moisture and heat tolerance of the two heterorhabditid strains was compared with a Turkish isolate of Steinernema feltiae. Significantly more nematodes invaded the insect Galleria mellonella in a sandy soil assay at 10% water content than at lower values. A higher water content significantly reduced the invasion rate. Steinernema feltiae was better adapted to a temperature of 32°C than the heterorhabditid strains. Hardly any nematodes of all strains survived for longer than 4 h at 36°C.
Formation conditions of vesicle/fissure–filling smectites in Penghu basalts: a stable-isotope assessment
Authors: Yui Tzen-Fu , Chang Shyun-Sheng 
Published: July 2002

AbstractStable isotope and chemical compositions of vesicle- and fissure-filling smectites (i.e. montmorillonite and saponite) in Penghu subaerial basalts were analysed to establish their possible formation conditions. The results show that montmorillonites have higher Fe contents (as FeOtotal), as well as higher O-isotope and H-isotope compositions than saponites. These differences may largely reflect dissimilar formation conditions and/or fluid compositions. It is suggested that saponites probably precipitated from fluids dominated by meteoric groundwaters at 40–50°C, whereas montmorillonites were probably formed at 20–40°C from mixtures of groundwaters and seawater. Considering all the possible uncertainties, the above estimated temperature conditions are suggested as reasonable lower limits.It is established that the associated calcite is not in O-isotope equilibrium with the montmorillonite. The calcite might have been formed in environments with ambient fluid dominated by meteoric groundwaters at temperatures lower than those for montmorillonite.
Surface modification of bentonites: I. Betaine montmorillonites and their rheological and colloidal properties
Authors: Schmidt C. U. , Lagaly G. 
Published: July 2002

AbstractMontmorillonite was modified by replacing the exchangeable cations with betaines(CH3)3N+ - (CH2)n - COO-M+ (n = 3, 5, 7, 10)The betaine derivatives delaminated in water and formed a colloidal dispersion. Air-drying of this material yielded hard pieces which were difficult to redisperse. The dried material became redispersible in water when the Na ions (counterions to the carboxyl groups) were replaced by Li ions. Colloidal dispersions of this material were more stable against salts than Li+- or Na+ - montmorillonite. Extremely high LiCl concentrations (>1 mol/l) were needed to coagulate the betaine derivatives (n>5) in the presence of diphosphate. The increased salt stability resulted from lyospheres around the silicate layers or thin packets of them which reduced the van der Waals attraction. Addition of organic solvents destabilized the dispersion by compressing the diffuse ionic layer (DLVO theory). The delaminated particles then aggregated to small flocs which settled very slowly. Neither band-type structures nor cardhouses were formed at conditions comparable to network formation and stiffening of Li- and Na-montmorillonite dispersions. Rheological measurements revealed the liquefying action of the betaines. Dispersions of butyrobetaine montmorillonite (15 g solid/l) revealed a relative viscosity (related to the dispersion medium water) ηrel ≈ 2. The longer chain derivatives showed a value slightly >1 whereas Li+-montmorillonite had ηrel = 8. Yield values were not formed at pH ≈ 7. Only at acidic conditions did the butyrobetaine montmorillonite dispersion showed a small yield value (<200 mPa).
Actin reorganization and proplatelet formation in murine megakaryocytes: the role of protein kinase Cα
Authors: Rojnuckarin Ponlapat , Kaushansky Kenneth 
Published: July 2002

AbstractWith the recent cloning and characterization of thrombopoietin, appreciation of the molecular events surrounding megakaryocyte (MK) development is growing. However, the final stages of platelet formation are less well understood. Platelet production occurs after the formation of MK proplatelet processes. In a study to explore the molecular mechanisms underlying this process, mature MKs isolated from suspension murine bone marrow cell cultures were induced to form proplatelets by exposure to plasma, and the role of various cell-signaling pathways was assessed. The results showed that (1) bis-indolylmaleimide I, which blocks protein kinase C (PKC) activation; (2) down-modulation of conventional or novel classes of PKC by phorbol myristate acetate; and (3) ribozymes specific for PKCα each inhibited proplatelet formation. Inhibition of several MAP kinases, PI3 kinase, or protein kinase A failed to affect MK proplatelet formation. To gain further insights into the function of PKCα in proplatelet formation, its subcellular localization was investigated. In cultures containing active proplatelet formation, cytoplasmic polymerized actin was highly aggregated, its subcellular distribution was reorganized, and PKCα colocalized with the cellular actin aggregates. A number of MK manipulations, including blockade of integrin signaling with a disintegrin or inhibition of actin polymerization with cytochalasin D, interrupted actin reorganization, PKC relocalization, and proplatelet formation. These findings suggest an important role for PKCα in proplatelet development and suggest that it acts by altering actin dynamics in proplatelet-forming MKs. Identification of the upstream and downstream pathways involved in proplatelet formation should provide greater insights into thrombopoiesis, potentially allowing pharmacologic manipulation of the process.
Association between polymorphisms of folate- and methionine-metabolizing enzymes and susceptibility to malignant lymphoma
Authors: Matsuo Keitaro , Suzuki Ritsuro , Hamajima Nobuyuki , Ogura Michinori , Kagami Yoshitoyo , Taji Hirofumi , Kondoh Eisei , Maeda Satoko , Asakura Shoji , Kaba Sadayuki , Nakamura Shigeo , Seto Masao , Morishima Yasuo , Tajima Kazuo 
Published: July 2002

Abstract
Genetic alteration is considered a probable cause of malignant lymphoma. Folate and methionine metabolism play essential roles in DNA synthesis and DNA methylation, and their metabolic pathways might thus affect disease susceptibility. In the present study, 2 polymorphisms were evaluated for a folate metabolic enzyme, methylenetetrahydrofolate reductase (MTHFR), and one was evaluated for methionine synthase (MS). The 2 polymorphisms, MTHFR677 C→T and MTHFR1298 A→C, are reported to reduce the enzyme activity, which causes intracellular accumulation of 5,10-methylenetetrahydrofolate and results in a reduced incidence of DNA double-strand breakage. The MS2756 A→G polymorphism also reduces the enzyme activity and results in the hypomethylation of DNA. To evaluate the association between malignant lymphoma susceptibility and these polymorphisms, hospital-based case-control study was conducted in Aichi Cancer Center. Ninety-eight patients with histologically confirmed lymphoma and 243 control subjects without cancer were evaluated. Unconditional logistic regression analyses revealed a higher susceptibility with the MTHFR677 CC and the MTHFR1298 AA genotypes (odds ratio, 2.26; 95% confidence interval, 1.26-4.02) when those harboring at least one variant allele in either polymorphism of MTHFR were defined as the reference. For the MS polymorphism, the MS2756 GG genotype also showed a higher susceptibility (odds ratio, 3.83; 95% CI, 1.21-12.1) than those with MS2756 AA or AG types. The significance was not altered when these 3 polymorphisms were evaluated in combination, and the results suggest that folate and methionine metabolism play important roles in the occurrence of malignant lymphomas. Further studies to confirm the association and detailed biologic mechanisms are now required.