bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current Applications and Research Trends of Ultrasound Examination in Acute Kidney Injury Assessment: A Bibliometric Analysis
Authors: Jiang Jiawei , Zhou Jinqiang , Bao Jiating , Gao Hongmei 
Published: December 2024

Abstract

Background: Acute kidney injury (AKI) is a significant clinical condition, and ultrasound examination has emerged as a crucial non-invasive imaging method for assessing kidney status, especially in its diagnosis and management. This study aims to perform a bibliometric analysis to clarify current research trends in ultrasound assessment of AKI.
Methods: We conducted a literature search in the Web of Science database using keywords related to ultrasound examinations of acute kidney injury, up to November 15, 2023. The results were analyzed using the bibliometric software package in R. Relevant literature information was analyzed.
Results: A total of 1,109 articles were included in the study. Research papers published between 2019 and 2024 demonstrated a significant upward trend. The United States, China, and Italy ranked as the top three countries in terms of publication volume. Among the top 10 research institutions with the highest number of publications, 6 are in the United States, with Université de Montréal being the institution with the most publications. Keyword trends focused on: resistive index, risk factors, therapy, glomerular filtration rate, survival, etc.
Conclusion: This bibliometric study highlights the advancements in ultrasound examination for AKI and underscores the importance of such analyses in determining research trends. Future research should emphasize the integration of various imaging techniques to improve diagnostic accuracy and clinical management of AKI.
Burden and complexity of multimorbidity: Findings from Dhulikhel Heart Study
Authors: Timalsena Dinesh , Chaudary Kalpana , Paneru Bandana , KC Sandip , Berger Ursula , Shrestha Archana 
Published: December 2024

Abstract

Background: Multimorbidity, defined as the coexistence of multiple chronic conditions within an individual, is increasingly recognized as a significant public health concern, particularly as populations age. While the prevalence of multimorbidity has been extensively studied in various global regions, there is limited data from Nepal. This study examines the burden and complexity of multimorbidity within the Dhulikhel Heart Study cohort in central Nepal.
Methods: We conducted a community-based cross-sectional study in Dhulikhel Municipality from July 2022 to June 2023, enrolling 1,608 participants aged 18 years and above. Data collection was performed through face-to-face interviews, and multimorbidity was defined as the presence of two or more chronic conditions. The conditions assessed included hypertension, diabetes, obesity, depression, kidney diseases, and several cardiovascular and respiratory disorders, among others. Sociodemographic and health-related behavioral variables were also analyzed.
Results: The overall prevalence of multimorbidity in the study population was 26.6%, with 27.0% among females and 26.0% among males. The prevalence of one, two, and three or more chronic conditions was 31.7%, 18.0%, and 8.6%, respectively. The odds of multimorbidity increased significantly with age (p-trend < 0.001). Compared to the 18-29 age group, the odds were 1.82 times higher for ages 30-39 (95% CI: 1.02 - 3.22), 4.27 times higher for ages 40-49 (95% CI: 2.38 - 7.64), 4.48 times higher for ages 50-59 (95% CI: 2.46 - 8.14), 6.68 times higher for ages 60-69 (95% CI: 3.60 - 12.40), and 7.01 times higher for those 70 years and older (95% CI: 3.62 - 13.57). Newar ethnicity had 1.70 times higher odds of multimorbidity (95% CI: 1.28 - 2.26, p < 0.001), and 'Other' ethnic groups (Dalit and Janajati) had 1.48 times higher odds (95% CI: 1.07 - 2.06, p = 0.016). Low physical activity was associated with 1.68 times higher odds of multimorbidity (95% CI: 1.28 - 2.21, p < 0.001).
Conclusion: The findings underscore the significant burden of multimorbidity in central Nepal, particularly among older adults. This highlights the need for targeted public health interventions and healthcare strategies to manage multimorbidity effectively, particularly as the population ages. The study provides critical insights into the epidemiology of multimorbidity in Nepal, which could inform future health policy and resource allocation.
Near-Infrared Long Lifetime Upconversion Nanoparticles for Ultrasensitive microRNA Detection via Time-Gated Luminescence Resonance Energy Transfer
Authors: Lee Joonseok , Kim Suyeon , Park Yeonkyung , Han Jiwoo , Kim Hansol , Jang Hyowon , Lee Min-Young , Jeong Byeong-Ho , Byun Yuree , Lim Eun-Kyung , Jung Juyeon , Kang Taejoon 
Published: December 2024

Abstract

Although upconversion nanoparticle (UCNP)-based luminescence resonance energy transfer (LRET) biosensing offers advantages such as wash-free detection and precise biomolecule quantification, there is still room for enhancing its sensitivity by preventing continuous energy transfer in co-doped UCNPs during LRET. In this study, we report a time-gated LRET approach using near-infrared (NIR) long-lived luminescent UCNP donors (L-TG-LRET), achieving an 8-fold increase in luminescence lifetime without compromising emission intensity. The extended and slower energy migration and transfer pathway of the L-TG-LRET approach significantly enhances sensitivity by preventing rapid Tm3+ reactivation of UCNPs during LRET from Tm3+ ions (800 nm emission) to IRDye800 acceptors (650–850 nm absorption). The developed L-TG-LRET system was applied to the detection of microRNAs (miRNAs), providing 17.9-fold higher sensitivity than conventional steady-state methods. Furthermore, this method has been successfully employed to determine the miRNA expression levels in cancer cells, patient plasma, and exosomes, enabling the differentiation of patients with lung and breast cancers from healthy donors. Notably, this approach demonstrated enhanced sensing performance compared to polymerase chain reaction (PCR) for the detection of low levels of exosomal miRNAs. These results highlighted the potential of the L-TG-LRET system as a valuable tool for sensitive biomolecular detection in clinical diagnostics.
Особенности выбора режимов лазерной термообработки плужного лемеха из стали 65Г
Authors: Луканин Б. Е. 
Published: December 2024

Лазерная термообработка является эффективным способом улучшения механических свойств и повышения износостойкости металлических деталей. В настоящей статье были рассмотрены особенности выбора режимов лазерной термообработки плужного лемеха из стали 65Г. Данный вид стали относится к углеродистым легированным сталям с высоким содержанием углерода, марганца и кремния. Она характеризуется высокой твердостью и прочностью, что делает ее прекрасным материалом для изготовления плужных лемехов, которые подвергаются значительным механическим нагрузкам и трению с почвой. Лазерная термообработка позволяет контролировать температурные зоны локально, что дает возможность изменять структуру и свойства материала для достижения оптимальных характеристик. При обработке плужных лемехов лазером применяются такие режимы, как нагрев, закалка и отпуск. Оптимальный выбор режимов лазерной термообработки плужного лемеха из стали 65Г позволит достичь требуемых механических свойств и повысить износостойкость детали. Комплексное рассмотрение свойств материала, геометрии и технических возможностей лазерной обработки позволит определить оптимальные параметры и достичь желаемых результатов.
Laser heat treatment is an effective way to improve the mechanical properties and increase the wear resistance of metal parts. This article examined the features of choosing laser heat treatment modes for a plow share made of 65G steel. This type of steel belongs to carbon alloy steels with a high content of carbon, manganese and silicon. It is characterized by high hardness and strength, which makes it an excellent material for the manufacture of plow shares, which are subject to significant mechanical loads and friction with the soil. Laser heat treatment allows you to control temperature zones locally, which makes it possible to change the structure and properties of the material to achieve optimal characteristics. When processing plow shares with a laser, modes such as heating, hardening and tempering are used. The optimal choice of laser heat treatment modes for a plow share made of 65G steel will allow you to achieve the required mechanical properties and increase the wear resistance of the part. A comprehensive consideration of the material properties, geometry and technical capabilities of laser processing will allow us to determine the optimal parameters and achieve the desired results.
The Needs and Experiences of People With Early-Stage Dementia Using an Application for Cognitive and Physical Activation in Germany: Qualitative Study
Authors: Klein Melina , von Bosse Alexa , Kunze Christophe 
Published: December 2024

Abstract

Background
The demand for support among people with dementia is increasing, while caregiving capacity is declining. As the trend of aging at home continues, technologies can help maintain the autonomy of people with dementia, enabling them to live independently for as long as possible. Furthermore, digital applications can have numerous positive biopsychosocial effects on the health of people with dementia, enhancing their physical, cognitive, and social functioning.

Objective
This study aims to investigate the needs and experiences of people with dementia regarding a prototype tablet-based application designed to promote cognitive and physical activity.

Methods
We conducted a methodical triangulation by combining semistructured interviews with people with dementia and external overt participant observation while testing a tablet-based application. A qualitative content analysis, as outlined by Kuckartz, was used to analyze the data.

Results
Participants demonstrated varying levels of ability and prior experience with technology. While most were initially hesitant to use the tablet independently, they were more willing to try it after receiving encouragement. Some individuals required more assistance than others, indicating the need for individualized adjustments. Personal relevance to the content appeared to be crucial for cognitive tasks, as it helped to minimize overload for people with dementia. The participants appreciated social interaction with researchers and direct communication. Therefore, it is important to consider the role of personal support when developing and implementing technology.

Conclusions
The successful implementation and use of technology requires acceptance and an effective interaction between people with dementia, technology, and caregivers or caring relatives providing personal support. The acceptance of the application was found to be less influenced by the types and presentation of tasks and more by content relevance and social interaction. Ideally, one-on-one support will be provided during use, though this requires additional time and financial resources, which are often limited in caregiving settings.
Visión de la Injuria como fuente de obligaciones en el derecho romano y su proyección al derecho actual = Vision of Injury as a source of obligations in roman law and its projection to current law
Authors: Estrada Susana Isabel 
Published: December 2024

Desde tiempos remotos la iniuria dentro de los delitos privados como fuente de las obligaciones fue considerada un acto contrario a derecho. La configuración de la tipicidad del delito de iniuria, comenzó con un alcance limitado en la ley de las XII Tablas como toda lesión física causada a la persona en su cuerpo, con dolo o con culpa. Merced a la intervención del pretor se amplió ese concepto comprendiendo no sólo la lesión física sino también las ofensas morales, el ataque al honor, la difamación verbal o escrita, la violación de domicilio o una lesión a la personalidad, con tal que se tome este término en sentido muy lato, porque no es romano pero es en lo posible exacto, al decir de Maynz. También en esta época aparece restringido el concepto al caso en que el autor del delito hubiera obrado con intención dolosa (animus iniuriandi). La evolución que experimentó la injuria como la mayoría de las figuras jurídicas se ha proyectado en el derecho actual, pero también éste se ha alejado en parte de las normas romanas. El propósito del presente trabajo es discernir en la comparación entre las regulaciones romanas y las actuales desde el Código de Vélez Sársfield pasando por la ley 17711 hasta llegar al Código Civil y Comercial de la Nación de 2015 y a las actuales posturas doctrinarias y jurisprudenciales en términos de similitudes y diferencias.

Abstract: Since ancient times, iniuria within private crimes as a source of obligations was considered an act contrary to law. The configuration of the typicity of the crime of iniuria, began with a limited scope in the law of the XII Tables as any physical injury caused to the person in his body, with intent or negligence. Thanks to the intervention of the praetor, this concept was expanded to include not only physical injury but also moral offenses, attacks on honor, verbal or written defamation, trespassing or personal injury, provided that this is taken term in a very broad sense, because it is not Roman but it is as exact as possible, according to Maynz. Also at this time the concept appears restricted to the case in which the perpetrator of the crime had acted with malicious intent (animus iniuriandi). The evolution experienced by injury, like most legal figures, has been projected into current law, but it has also partly distanced itself from Roman norms. The purpose of this work is to discern in the comparison between the Roman regulations and the current ones from the Code of Vélez Sársfield through the law 17711 until reaching the Civil and Commercial Code of the Nation of 2015 and the current doctrinal positions. and jurisprudential in terms of similarities and differences.
Phenotypic Versus Genetic Mismatch of BMI and Type 2 Diabetes: Evidence From Two Prospective Cohort Studies
Authors: Li Aolin , Gong Shuo , Yu Canqing , Pei Pei , Yang Ling , Millwood Iona Y. , Walters Robin G. , Chen Yiping , Du Huaidong , Yang Xiaoming , Hou Wei , Chen Junshi , Chen Zhengming , Lv Jun , Li Liming , Sun Dianjianyi ,   China Kadoorie Biobank Collaborative Group
Published: December 2024

Little is known about the population-based mismatch between phenotypic and genetic BMI (BMI-PGM) and its association with type 2 diabetes. We therefore used data from the China Kadoorie Biobank and UK Biobank and calculated BMI-PGM for each participant as the difference between the percentile for adjusted BMI at baseline and the percentile for adjusted polygenic risk score for BMI. Participants were categorized into discordantly low (BMI-PGM &lt; the first quartile), concordant (the first quartile ≤ BMI-PGM &lt; the third quartile), and discordantly high (BMI-PGM ≥ the third quartile) groups. We calculated adjusted hazard ratios (HRs) for the association of BMI-PGM and type 2 diabetes using Cox proportional hazard models in each cohort, and combined HRs using random-effects meta-analyses. During a median follow-up of 12 years for both cohorts, BMI-PGM was associated with the risk of type 2 diabetes, with the discordantly low group showing reduced risk and the discordantly high group showing elevated risk compared with the concordant group, independent of BMI and other conventional risk factors. In addition, normal-weight individuals with discordantly high BMI-PGM faced a higher risk of type 2 diabetes than overweight individuals. These findings suggest that BMI-PGM may play a potential role in reassessing the risk of type 2 diabetes, particularly among normal-weight populations.

Article Highlights
Social developments have fostered an “obesogenic environment” that exacerbated phenotypic versus genetic mismatch of BMI (BMI-PGM) and the risk of type 2 diabetes. The study quantified BMI-PGM and examined its association with type 2 diabetes independent of BMI and other conventional factors. The risk of type 2 diabetes was lower in the discordantly low BMI-PGM group and higher in the discordantly high BMI-PGM group, with concordant BMI-PGM group as reference. These findings indicate the potential to reassess type 2 diabetes risk by quantifying BMI-PGM on individual levels.
Effects of Pilot Oil Injection Timing on Combustion, Covariance and Knocking of a Natural Gas–Diesel Duel-Fuel Low-Speed Engine
Authors: Wei Cunfeng , Chen Xiang-Xiang , Chen Liang , Li Pengfei , Liu Mingrui 
Published: December 2024

Abstract
Dual-fuel engines, which are powered by natural gas while using a small amount of diesel for ignition, have become an attractive option in the marine sector due to their fuel flexibility and relatively good emission characteristics. Altering the fuel injection timing can change the combustion state of natural gas in the cylinder, which in turn affects engine stability and leads to engine knocking.
In this study, the effects of different pilot oil injection timings on the combustion stability of a marine low-speed natural gas dual-fuel engine with a pre-combustion chamber are evaluated in terms of the pressure rise, covariance of Pmax and IMEP, combustion phase, and knocking. It is found that the maximum cylinder pressure and pressure rise rate increase with an advance in the pilot oil injection time. After the natural gas enters the combustion chamber, it undergoes a process of mixing with air in the combustion chamber, and earlier pilot oil injection leads to an increase in the ignition delay period and shortens the combustion duration of the engine. Moreover, it is found that earlier pilot oil injection times result in an increase in engine IMEP and Pmax cycle fluctuations, and engine knocking also undergoes an increase when the pilot oil injection time is advanced. Hence, an appropriate pilot oil injection time should be considered in the process of optimising engine performance.
El papel de la Termografía infrarroja en el diagnóstico de Trastornos Temporomandibulares: Revisión Narrativa - 2023.
Authors: Mora Caicedo Richard Fernando , Balanta Julián , Contreras Renjifo Adolfo 
Published: December 2024

Los Trastornos temporomandibulares son un colectivo de condiciones musculoesqueléticas que causan dolor y disfunción en los músculos masticatorios, la articulación temporomandibular y regiones anatómicas asociadas, afecta al 5-12% de la población, generando el tipo más común de dolor orofacial no odontogénico, que a su vez incrementa los costos de la atención en los sistemas de salud y en reducción de la calidad de vida. Dichas patologías debido a procesos fisiológicos del dolor y anormalidad en la función pueden generar cambios en la temperatura, por lo cual se ha evaluado en su valoración una herramienta tecnológica emergente llamada Termografía Infrarroja, que permite medir temperaturas a distancia lo cual podría coadyuvar un diagnóstico clínico. Por lo que múltiples ensayos clínicos han hecho uso de dicha tecnología basada en la heterogeneidad térmica de distintos tejidos y su flujo sanguíneo los cuales son directamente proporcionales con la actividad metabólica, es por ello por lo que se requiere hacer una revisión de la literatura, los avances y resultados de dichos estudios.
Objetivo: Efectuar una descripción general de los principales hallazgos y conclusiones de la evidencia clínica disponible sobre la efectividad de la termografía infrarroja en el diagnostico de trastornos temporomandibulares.
Materiales y métodos: La búsqueda inicial abarcó 62 artículos, de los cuales se seleccionaron 11 para esta revisión, distribuidos en Norteamérica 38%, en Europa 14% y 48% en Sudamérica. Se realizó una extensa búsqueda electrónica en las bases de datos: Pubmed, Epistemonikos y Cochrane Library.
Conclusión: La mayoría de los estudios evaluados han concluido a la termografía como una tecnología prometedora en el diagnostico de trastornos de la articulación temporomandibular, la literatura es altamente variable en criterios de fiabilidad del uso de este instrumento para el diagnóstico de los trastornos temporomandibulares, lo que se ve reflejado en valores de sensibilidad y especificidad con rangos diferenciales ampliamente marcados.
Implementasi Metode Content Based Filtering pada Pengembangan Sistem Bursa Kerja Khusus (BKK) SMK Negeri 1 Kandeman Berbasis Website
Authors: Anam Khoirul , Gutama Deden Hardan , Danianti Dita , Prastowo Wahit Desta 
Published: December 2024

Abstrak— Kebutuhan akan sistem informasi yang efisien dan efektif semakin meningkat, termasuk dalam bidang pencarian kerja. Penelitian ini bertujuan untuk mengembangkan sistem Bursa Kerja Khusus (BKK) berbasis website di SMK Negeri 1 Kandeman dengan menerapkan metode Content Based Filtering. Metode ini digunakan untuk merekomendasikan lowongan pekerjaan kepada pengguna berdasarkan kesesuaian profil dan preferensi mereka dengan pekerjaan yang tersedia. Sistem ini dirancang menggunakan bahasa pemrograman PHP dan MySQL sebagai basis data. Dalam implementasinya, metode Content Based Filtering bekerja dengan menganalisis deskripsi pekerjaan dan data pengguna, seperti jurusan, skill, dan kota untuk menghasilkan rekomendasi pekerjaan yang relevan. Uji coba sistem dilakukan dengan melibatkan sejumlah pengguna untuk mengevaluasi keefektifan dan akurasi rekomendasi yang dihasilkan. Hasil penelitian menunjukkan bahwa sistem BKK berbasis website ini mampu memberikan rekomendasi pekerjaan yang sesuai dengan profil pengguna, sehingga meningkatkan efisiensi dalam proses pencarian kerja. Dengan demikian, diharapkan sistem ini dapat menjadi solusi yang efektif bagi siswa dan alumni SMK Negeri 1 Kandeman dalam mencari pekerjaan yang sesuai dengan keahlian dan minat mereka.Kata kunci: Bursa Kerja Khusus (BKK), Content Based Filtering, Sistem Informasi, Rekomendasi Pekerjaan, SMK Negeri 1 Kandeman, Website, PHP, MySQL, Profil Pengguna. Abstract — The need for efficient and effective information systems is increasing, including in the field of job search. This research aims to develop a website-based Special Job Exchange (BKK) system at SMK Negeri 1 Kandeman by applying the Content Based Filtering method. This method is used to recommend job vacancies to users based on the suitability of their profiles and preferences with available jobs. The system is designed using PHP programming language and MySQL as the database. In its implementation, the Content Based Filtering method works by analysing job descriptions and user data, such as majors, skills, and cities to generate relevant job recommendations. System trials were conducted involving a number of users to evaluate the effectiveness and accuracy of the recommendations generated. The results show that this web-based BKK system is able to provide job recommendations that match the user's profile, thus increasing efficiency in the job search process. Thus, it is expected that this system can be an effective solution for students and alumni of SMK Negeri 1 Kandeman in finding jobs that match their expertise and interests.Keywords: Bursa Kerja Khusus (BKK), Content Based Filtering, Information System, Job Recommendation, SMK Negeri 1 Kandeman, Website, PHP, MySQL, User Profile.