bluuebunny/crossref_metadata_2025_split huggingface dataset:
REHABILITASI MEDIK PADA SINDROM EHLERS-DANLOS
Authors: Chandra Ivan A. , Angliadi Engeline 
Published: July 2019

Abstract: Ehlers-Danlos syndrome is a group of inherited connective tissue disorders that manifests as hypermobility joint, hyperextensibility of the skin, and tissue fragility. There are 6 variants of this syndrome as follows: hypermobility, classic, vascular, kyphoscoliosis, athroclasia, and dermatosparaxis. The clinical manifestation of Ehlers-Danlos syndrome is often related to joint and skin. However, it rarely manifests as fragility or rupture of artery, scoliosis, and mitral valve disorder. The diagnosis of Ehlers-Danlos syndrome is based on clinical findings, family history with this syndrome, and additional tests inter alia DNA test. The management of Ehlers-Danlos syndrome could be medication, surgery, and rehabilitation. This rehabilitation is focused on increasing the joint stability, prohibiting for excessive burden to weight bearing joints, and using modified device to support activites of daily living without worsening the symptoms as well as supporting the psychological and medical social aspects of the patient. Keywords: Ehlers-Danlos syndrome, joint hypermobility, comprehensive rehabilitation Abstrak: Sindrom Ehlers-Danlos (SED) adalah sekelompok gangguan pada jaringan penyambung yang bersifat diturunkan dan bermanifestasi sebagai hipermobilitas sendi, hiperekstensibilitas kulit, dan kerapuhan jaringan. Terdapat 6 jenis SED yaitu: hipermobilitas, klasik, vaskuler, kifoskoliosis, artrokalasia, dan dermatosparaksis. Manifestasi klinis SED sering berkaitan dengan sendi dan kulit. Manifestasi lain yang lebih jarang ditemukan antara lain kerapuhan atau ruptur pembuluh darah arteri, skoliosis, serta gangguan katup mitral. Diagnosis SED ditegakkan berdasarkan penemuan klinis, riwayat keluarga dengan SED, serta pemeriksaan penunjang antara lain tes DNA. Penanganan SED terdiri dari medikasi, operasi, dan rehabilitasi. Penanganan rehabilitasi difokuskan pada peningkatan stabilitas sendi, pencegahan beban berlebih pada sendi yang weight bearing, serta penggunaan modifikasi alat untuk membantu aktifitas sehari-hari tanpa memperberat gejala. Selain itu, rehabilitasi medik juga berperan penting terhadap aspek psikologik maupun sosial medik pasien SED. Kata kunci: sindroma Ehlers-Danlos, hipermobilitas sendi, rehabilitasi komprehensif
TERAPI LARVA PADA LUKA KRONIS TERBUKA
Authors: Wangko Sunny 
Published: July 2019

Abstract: The usage of larvae in wound treatment has been known across the centuries in different countries. However, larval therapy is offered when the conventional therapy has failed in the management of chronic, infected wounds. Concerning the larval therapy, it was presumed that the wound healing was due to the mechanical debridement effect of the larval movement and of their hooks. To date, a variety of study reports reveals that there are several beneficial effects of the larval therapy, inter alia: secretion/excretion of larvae contains enzymes, growth factors, and cytokines that collaborate in the wound healing process. The bioactive molecules in the secretion/excretion of the larvae has to be further studied and to be developed, therefore, they can be applied in the wound management efficiently and economically. Keywords: larval therapy, chronic wound, healing process. Abstrak: Walaupun pemanfaatan larva pada luka kronis telah sangat lama dikenal di berbagai negara, terapi larva umumnya digunakan bila terapi konvensional telah gagal. Awalnya diduga bahwa efek debridemen mekanis oleh gerakan larva dan kaitnya yang paling berperan. Dewasa ini, laporan berbagi studi telah mengungkapkan bahwa larva menyekresi dan menyintesis berbagai bahan baik berupa enzim, sitokin, dan growth factors yang turut berperan dalam proses penyembuhan luka. Adanya molekul bioaktif dalam ekskresi dan sekresi larva perlu diteliti dan dikembangkan agar dapat diaplikasikan dengan lebih efisien dan ekonomis. Kata kunci: terapi larva, luka kronis, penyembuhan luka.
ECOLOGICAL AND MICROBIOLOGICAL ASSESSMENT OF SEWAGE SLUDGE OF WASTE TREATMENT PLANTS IN THE CITY OF ODESA
Authors: Dyshliuk V.Ye. , Pyliak N.V. , Loban L.L. 
Published: July 2019

Objective. Investigate the number of microorganisms – representatives of various ecological trophic groups in mechanically dewatered and naturally disinfected sewage sludge (SS) of the biological sewage treatment plants (BSTP) “Pivnichna” and “Pivdenna” of the City of Odesa to determine their suitability for microbiological parameters for use as fertilizers in agriculture.
Methods. Microbiological, statistical.
Results. It was established that SS of BSTP “Pivdenna” and “Pivnichna” in the City of Odesa, bacteria that consume organic and mineral nitrogen compounds, phosphate-mobilizing microorganisms, are actively developing, due to the presence of the corresponding trophic substrates. By the number of ammonifiers, microorganisms that consume mineral compounds of phosphorus and bacteria capable of hydrolyzing the organophosphates, spore microorganisms, the waste is inferior to traditional organic manure – animal manure. The functional orientation of microbiological processes in the studied substrates is determined on the basis of the obtained data, calculations of the mineralization-immobilization factors and the oligotrophic index. The parameters of the mineralization-immobilization factors (0.04-0.2) in the SS indicate the predominance of synthesis processes over the destruction of organic matter. The oligotrophic index (an indicator of the supply of substrates with easily digestible nutrients) shows insignificant content of nutrients available for microorganisms in SS from BSTP “Pivnichna” (OI = 1.0) and a high level of supply with nutrients of SS from BSTP “Pivdenna” (OI = 0.1). In general, according to microbiological parameters, investigated SS are suitable for use as fertilizing substrates in agriculture.
Conclusion. Taking into account the obtained data and taking into account the results of previous studies on the compliance of SS with sanitary regulations, it can be considered that the use of SS as fertilizers will have a positive effect on the functioning of agrocenoses.
DEVELOPMENT OF MICROORGANISMS AND TRENDS OF BIOLOGICAL PROCESSES IN LEACHED CHORNOZEM UNDER SIMULATION OF DEFICIENCY OF THE FRESH ORGANIC MATTER AND THE INFLUENCE OF MINERAL NITROGEN
Authors: Volkohon V.V. , Brytan T.Yu. , Pyrih O.V. 
Published: July 2019

Objective. Study the peculiarities of the development of microorganisms and trends of biological processes in the soil under the influence of mineral nitrogen under the conditions of simulation of the deficiency of fresh organic matter.
Methods. Microbiological, agrochemical, gas chromatographic, statistical.
Results. In the conditions of the vegetative experiment under the simulation of the deficiency of fresh organic matter (preparation of soil in accordance with the method of determining the content of humus) in the leached chornozem, the effect of increasing doses of mineral nitrogen on the dynamics of the number of representatives of certain ecological trophic groups of microorganisms and the course of soil-biological processes that accompany the mineralization of humus was studied. Nitrogen fertilizers, under given conditions, stimulate the development of ammonifiers, microorganisms that mainly utilize mineral compounds of nitrogen, denitrifiers, cellulolytic bacteria, activates biological nitrogen and carbon dioxide emission processes. In this case, the need for carbon to provide metabolic processes of microorganisms can meet only at the expense of destruction of humus compounds. When the fresh organic matter is introduced in the soil in the form of straw chopped to sawdust, as well as under the growth of barley, the activity of biological denitrification is reduced. At the end of the experiment, the content of total carbon in the soil has a clear tendency to decrease with increasing doses of mineral nitrogen – according to the variants: without fertilizers, control – 2.97 %, 13 mg N/kg of soil – 2.91 %, 26 mg N/kg – 2.88 %, 39 mg N/kg – 2.85 %.
Conclusion. Under the deficiency of fresh organic matter in leached chornozem, the depleted use of mineral nitrogen fertilizers, especially in large quantities, leads to the creation of a situation where microorganisms for the maintenance of metabolic needs use carbon-preservative organic compounds. The use of mineral nitrogen, not coordinated with the required amount of fresh organic matter, leads to the initiation of dehumidification processes. To prevent such effects, environmentally sound fertilizer systems for crops should include systematic entry of fresh organic matter into the soil.
The effect of heat-treatment on morphology and mobility of Au nanoparticles
Authors: Oras Sven , Vlassov Sergei V , Polyakov Boris , Antsov Mikk , Lõhmus Rünno , Mougin Karine 
Published: July 2019

In the present paper we investigate the effect of heat-treatment on geometry and mobility of Au nanoparticles (NPs) on Si substrate. Chemically synthesized Au nanoparticles with median diameter of 14 nm were annealed at 200°C, 400°C, 600°C and 800°C for 1 hour. Geometry changes from faceted towards more rounded shapes were observed already for 200oC and increased further for higher temperatures. According to KCM simulations NPs become rounded through the minimization of the surface area and transitioning to lower energy surface types {111} and {100}. Next, NPs were manipulated with AFM and it was found that the higher is annealing temperature, the less energy was required to displace the particle. However, after treatment at 800°C particles became immovable. We attributed this surprising effect to diffusion of gold into Si and to the growth of SiO2.
Efficient Computation of Collisional ℓ-mixing Rate Coefficients in Astrophysical Plasmas
Authors: Vrinceanu D. , Onofrio R. , Oonk J. B. R. , Salas P. , Sadeghpour H. R. 
Published: July 2019

Abstract
We present analytical expressions for direct evaluation of ℓ-mixing rate coefficients in proton-excited hydrogen atom collisions and describe a software package for efficient numerical evaluation of the collisional rate coefficients. Comparisons between rate coefficients calculated with various levels of approximation are discussed, highlighting their range of validity. These rate coefficients are benchmarked for radio recombination lines for hydrogen, evaluating the corresponding departure coefficients from local thermal equilibrium.
12,660 Spotted Stars toward the OGLE Galactic Bulge Fields
Authors: Iwanek P. , Soszyński I. , Skowron J. , Udalski A. , Stępień K. , Kozłowski S. , Mróz P. , Poleski R. , Skowron D. , Szymański M. K. , Pietrukowicz P. , Ulaczyk K. , Wyrzykowski Ł. , Kruszyńska K , Rybicki K. 
Published: July 2019

Abstract
We present the discovery and statistical analysis of 12,660 spotted variable stars toward and inside the Galactic bulge from the Optical Gravitational Lensing Experiment (OGLE) data that are over two decades long. We devise a new method of dereddening of individual stars toward the Galactic bulge where strong and highly nonuniform extinction is present. In effect, 11,812 stars were classified as giants and 848 as dwarfs. Well-defined correlations among the luminosity, variability amplitude, and rotation period were found for the giants. Rapidly rotating dwarfs with periods P ≤ 2 days show I-band amplitudes <0.2 mag, which is substantially less than the amplitudes of up to 0.8 mag observed in giants and slowly rotating dwarfs. We also notice that amplitudes of stars brighter than I
0 ≈ 16 mag do not exceed 0.3–0.4 mag. We divide the stars into three groups characterized by correlation between light and color variations. The positive correlation is characteristic for stars that are cooler when fainter, which results from the variable coverage of the stellar surface with spots similar to the sunspots. The variability of stars that are cooler when brighter (negative correlation) can be characterized by chemical spots with an overabundance of heavy elements inside and a variable line-blanketing effect, which is observed in chemically peculiar stars. The null correlation may result from a very high level of the magnetic activity with rapidly variable magnetic fields. This division is readily visible on the color–magnitude diagram (CMD), which suggests that it may depend on the radius of the stars. We detect 79 flaring objects and discuss briefly their properties. Among others, we find that relative brightening during flares is correlated with brightness amplitude.
Doux commerce et droit naturel : la fable de la lex mercatoria
Authors: Marquer Éric 
Published: July 2019

Pour justifier leur activité, les premiers mercantilistes anglais présentent le commerce comme une activité naturelle, qui favorise la paix entre les nations et contribue au progrès de la civilisation. Ils ont en particulier recours à la lex mercatoria, notion héritée du Moyen Âge. L’idée d’un commerce mutuel de l’humanité, mise en avant dans les écrits de marchands, mais également chez un auteur comme Grotius, contraste ainsi avec les théories de la souveraineté liée à un territoire national chez des penseurs politiques comme Francis Bacon, Thomas Hobbes et William Petty, ou à certains égards chez un juriste comme John Selden. Paradoxalement, alors que la constitution des empires coloniaux coïncide avec l’essor du grand négoce international, la liberté du commerce (free trade) est présentée par ses défenseurs comme une alternative à l’antagonisme entre les États et à la logique de domination induite par les théories modernes de l’imperium. Cette apparente contradiction entre la logique étatique et l’humanisme marchand – ou ce qui se présente comme tel – semble subsister dans les résurgences modernes de la lex mercatoria au XXe siècle. Pourtant, l’idée d’une source du droit indépendante de l’État et s’enracinant dans l’ancienneté des coutumes, l’uniformité des pratiques marchandes ou encore le jus gentium, relève en grande partie de la fable, et d’une construction idéologique visant à dissimuler la réalité des pratiques commerciales. De ce point de vue, la fable de la lex mercatoria joue très certainement un rôle important dans la constitution du topos du doux commerce et la promotion de la liberté des échanges par ceux qui en sont, directement ou indirectement, les principaux bénéficiaires.
Hayek, penseur du « doux commerce » : la société moderne est-elle principalement soudée par des « réseaux d’argent » ?
Authors: Debray Eva 
Published: July 2019

On insiste le plus souvent, que ce soit pour critiquer ou féliciter l’entreprise de l’économiste Friedrich August von Hayek, sur sa reprise de l’expression de « main invisible » d’Adam Smith. Hayek voit dans cette métaphore une manière particulièrement heureuse de traiter de ces ordres spontanés, de ces ordres produits de manière non intentionnelle, dont lui-même cherche à rendre compte, et, plus précisément, l’ordre de marché. Cependant, plusieurs questions restent alors ouvertes lorsque l’on emprunte uniquement cette voie : de quoi Hayek cherche-t-il à rendre compte précisément lorsqu’il traite de ces ordres spontanés, c’est-à-dire que signifie le terme d’ordre ici ? Pourquoi se penche-t-il principalement sur l’ordre économique ? Pour répondre à ces questions, il est utile de mettre au jour une autre réappropriation conceptuelle à laquelle procède Hayek : celle qui prend pour objet le thème du doux commerce. Son analyse nous place au cœur de son projet de défense du libéralisme. Une étude adéquate de ce réinvestissement suppose cependant de mettre au jour le déplacement conceptuel qu’Hayek fait subir à ce thème. Il s’agit en effet pour ce dernier de défendre l’idée que les « “réseaux d’argent” […] soudent la Grande Société », c’est-à-dire sont au principe de l’ordre pacifique de la société moderne.
Au service du roi très chrétien
Authors: Schnyder Marco 
Published: July 2019

La thématique de la présence étrangère à la cour de France est abordée à travers le cas de la famille de Besenval, originaire du Val d’Aoste, mais établie à Soleure à partir de 1628. Cette ville suisse, chef-lieu du canton homonyme et demeurée catholique, était également, depuis 1530, le siège de l’ambassade française permanente dans l’ancienne Confédération suisse. Les Besenval s’engagent avec succès dans les domaines d’activité privilégiés par l’élite dirigeante locale : magistratures et service militaire à l’étranger. Ce dernier fait entrer définitivement la famille dans l’orbite française. Par leur service à la Couronne sur les champs de bataille au cours du xviie siècle, les Besenval sont anoblis et deviennent, aux yeux des Bourbons, de précieux et fidèles serviteurs. Non seulement comme représentants du parti français au sein du Corps helvétique, mais également comme seigneurs et propriétaires fonciers dans une région récemment conquise, comme l’Alsace, et en tant que diplomates pour le compte de la Couronne. Certains Besenval font une expérience directe de la Cour, à Versailles, d’autres indirecte, à l’étranger, tant auprès de l’ambassade française à Soleure que lors de missions diplomatiques, comme en Pologne ou auprès des cours du Nord. Pour cette famille aux intérêts transnationaux, être courtisan ou simplement être proche de la Cour, n’est finalement ni un but en lui-même ni une simple étape. Être présent à la fois à Soleure et à Paris est indispensable afin de conserver un pouvoir qui est par nature transnational.
Quand les civils maintiennent l’ordre. Configurations vigilantes à Istanbul
Authors: Massicard Elise 
Published: July 2019

Résumé : Depuis les années 2000 se font jour dans le quartier de Tophane (Istanbul) des pratiques de maintien de l’ordre par des civils articulant violence politique, lutte contre la criminalité et police des mœurs plus diffuse. Le terme de « configuration vigilante » permet de les saisir dans leur fluidité, tout en prenant acte de leur caractère relativement structuré et de leur mise en cohérence par des discours charriant des imaginaires et des modèles de rôle. Des entrepreneurs de morale locaux relativement autonomes portent ces croisades, ce qui différencie cette situation de contextes moyen-orientaux dans lesquels l’existence ordinaire d’indics laisse supposer des mobilisations provoquées par le haut. C’est la proximité politique avec les acteurs du pouvoir qui vaut à ces pratiques d’être tolérées, voire discrètement encouragées par eux – et qui les distingue d’autres formes civiles de maintien de l’ordre dans d’autres quartiers d’Istanbul qui, marquées à gauche, sont plus sévèrement réprimées.
La guerre Iran-Irak (1980-1988) à la télévision française
Authors: Devictor Agnès 
Published: July 2019

Comment les médias télévisuels français ont-ils couvert la guerre Iran-Irak (1980-1988) ? À quels imaginaires se sont-ils référés ? Pourquoi et comment le contexte politique, économique et social en France a-t-il aussi interféré dans la production médiatique du conflit ? Fondé sur une étude systématique des huit ans de cette guerre telle que l’a montrée la télévision française, cet article vise à analyser les glissements qui se sont opérés, allant d’une présentation d’une guerre conventionnelle et lointaine, à sa mise en parallèle avec la Première Guerre mondiale pour déboucher sur l’apparition d’une grande peur de l’islam. Il vise aussi à compléter les études sur la cristallisation des représentations de la « menace islamique » en France dans les années 1980.
Roles of T Follicular Helper Cells and T Follicular Regulatory Cells in Autoantibody Production in IL-2–Deficient Mice
Authors: Xie Markus M , Liu Hong , Corn Caleb , Koh Byung-Hee , Kaplan Mark H , Turner Matthew J , Dent Alexander L 
Published: July 2019

Abstract
Autoantibodies can result from excessive T follicular helper (Tfh) cell activity, whereas T follicular regulatory (Tfr) cells negatively regulate autoantibody production. IL-2 knockout (KO) mice on the BALB/c background have elevated Tfh responses, produce autoantibodies, and develop lethal autoimmunity. We analyzed Tfh and Tfr cells in IL-2 KO mice on the C57BL/6 (B6) genetic background. In B6 IL-2 KO mice, the spontaneous formation of Tfh cells and germinal center B cells was greatly enhanced, along with production of anti-DNA autoantibodies. IL-2 has been reported to repress Tfr cell differentiation; however, Tfr cells were not increased over wild-type levels in the B6 IL-2 KO mice. To assess Tfh and Tfr cell regulation of autoantibody production in IL-2 KO mice, we generated IL-2 KO mice with a T cell–specific deletion of the master Tfh cell transcription factor Bcl6. In IL-2 KO Bcl6 conditional KO (2KO-Bcl6TC) mice, Tfh cells, Tfr cells, and germinal center B cells were ablated. In contrast to expectations, autoantibody IgG titers in 2KO-Bcl6TC mice were significantly elevated over autoantibody IgG titers in IL-2 KO mice. Specific deletion of Tfr cells with Foxp3-cre Bcl6-flox alleles in IL-2 KO mice led to early lethality, before high levels of autoantibodies could develop. We found IL-2+/+ Tfr cell–deficient mice produce significant levels of autoantibodies. Our overall findings provide evidence that Tfh cells are dispensable for high-level production of autoantibodies and also reveal a complex interplay between Tfh and Tfr cells in autoantibody production and autoimmune disease.
Identifying Homogeneous Outcome Groups in Adult Rehabilitation Using Cluster Analysis
Authors: Custer Melba G. , Huebner Ruth A. 
Published: July 2019

AbstractImportance: Adults receiving occupational therapy in inpatient rehabilitation are a heterogeneous population with differing needs, outcomes, and rehabilitation processes. Outcome studies based on what works for all clients may obscure the needs of population subgroups who benefit unequally from rehabilitation services.Objective: To identify subgroups on the basis of client satisfaction and progress in functional self-care among a diverse rehabilitation population and to understand subgroup differences in occupational therapy and rehabilitation processes and client discharge status.Design: Using an existing dataset, we used K-means cluster analysis of demographics, status at admission, and the outcomes of satisfaction and change in self-care to identify five homogeneous outcome groups. Occupational therapy and rehabilitation processes and discharge status were compared across subgroups.Setting: Inpatient rehabilitation hospital.Participants: The dataset included 1,099 inpatients age 18 yr and older who received occupational therapy over a 27-mo period.Measures: Admission measures included the Inpatient Rehabilitation Facility–Patient Assessment Instrument and self-care items of the FIM™. The Satisfaction with Continuum of Care–Revised was administered after discharge.Results: Five subgroups showed statistically different patterns of medical complications, functional self-care, rates of progress, satisfaction with intervention, and course of treatment. The profile of each group suggests differing therapeutic needs. Although all groups made significant gains in functional self-care, two groups continued to need physical assistance at discharge.Conclusions and Relevance: Cluster analysis proved useful in segmenting a typical heterogeneous rehabilitation population into more homogeneous subgroups to enhance understanding of clinical needs and to potentially increase the potency of outcomes research.What This Article Adds: This research identified subgroups within a typical population of rehabilitation clients receiving occupational therapy and identified their unique needs and outcomes using cluster analysis techniques.