bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ankle Sprain Versus Muscle Strain Injury in Professional Men’s Basketball: A 9-Year Prospective Follow-up Study
Authors: Rodas Gil , Bove Toni , Caparrós Toni , Langohr Klaus , Medina Daniel , Hamilton Bruce , Sugimoto Dai , Casals Martí 
Published: June 2019

Background: Ankle sprain is the most common injury in basketball players. However, in our routine clinical evaluation, we observe a high frequency of muscle injury. Currently, no reliable information is available regarding the magnitude of these types of injury. Purpose: To describe the type and rate of muscle injuries in male basketball players and discuss clinical management and prevention strategies. Study Design: Descriptive epidemiology study. Methods: A total of 59 professional male basketball players were evaluated over 9 seasons (2007-2015). All injuries during the study period were registered through use of a validated electronic medical record system. Results: We analyzed 463 injuries, of which 207 resulted in time loss and 256 required medical attention, for a total exposure time of 42,678 hours for the 59 players involved in the study. Muscle strains and ankle sprains accounted for 21.2% (n = 98) and 11.9% (n = 55) of all injuries, respectively. The global incidence rate was 10.8 injuries per 1000 player-hours (95% CI, 9.9-11.9). The global injury burden was 53.9 days lost due to injuries per 1000 hours for a total exposure time. The incidence rate of muscle strains (2.3; 95% CI, 1.9-2.8) was higher than that of ankle sprains (1.3; 95% CI, 1-1.7). The incidence rate for muscle injuries for the entire study period was 1.8 times higher (95% CI, 1.28-2.49) than that for ankle sprains. Conclusion: In this study, muscle injuries were more commonly observed compared with ankle sprains. Prevention strategies for muscle injuries may be worth discussing.
Utility of MRI in the Evaluation of Acute Greater Tuberosity Proximal Humeral Fractures
Authors: Pitcher Austin , Langhammer Christopher , Feeley Brian T. 
Published: June 2019

Background: Understanding soft tissue injury patterns associated with greater tuberosity (GT) fractures may help clinicians provide guidance to patients. Hypothesis: Evaluating magnetic resonance imaging (MRI) findings in patients with suspected isolated GT fractures will help elucidate the role of MRI in the diagnosis and treatment of these patients. Study Design: Case series; Level of evidence, 4. Methods: We performed a retrospective review of medical records from 2010 to 2014 for patients presenting with acute isolated GT fractures and MRI. Uncomplicated and delayed recovery groups were established according to the need for delayed procedural intervention or persistent symptoms past last recorded follow-up. Multivariate regression analysis was used to analyze the relationships between MRI findings and delayed recovery. Results: A total of 32 patients met the inclusion criteria (mean age, 47 years [range, 24-88 years]; mean follow-up, 30 weeks [range, 33 days–4 years]). There was no significant difference in the estimation of fracture displacement as measured on radiography and compared with MRI (radiography, 2.8 mm; MRI, 3.5 mm; P = .16). There was a high incidence of full-thickness rotator cuff tears (9%), partial-thickness rotator cuff tears (72%), partial biceps tendon tears (41%), and labral tears (50%). Presence of biceps pathology or partial-thickness rotator cuff tear was predictive of delayed recovery in a multivariate model. Conclusion: There is a high incidence of soft tissue injury found by MRI following GT fracture. MRI did not appreciably change the measure of displacement of the fracture fragment. In the multivariate analysis, presence of a partial-thickness rotator cuff tear or biceps tendon injury was associated with delayed recovery.
Effect of military expenditure on economic growth: evidences from India Pakistan and China using cointegration and causality analysis
Authors: Raju Mohammad Hasan , Ahmed Zobayer 
Published: June 2019

AbstractThe study revisited the existing evidences of India Pakistan and China with updated data on the effect of military expenditure on economic growth. Econometric approaches analyzed the short and long run relationship between GDP growth and Military expenditure. Empirical studies have been done using cointegration analysis and causality test to justify the relationship and causality of the variables. Interestingly, study obtained positive log-run relation, no short run relationship and unidirectional long run causality in every cases, but for different degrees of relationship. Obtained results are robust and passed necessary diagnostic tests significantly.
Creating a Synthetic Clinical Trial: Comparative Effectiveness Analyses Using an Electronic Medical Record
Authors: Zauderer Marjorie G. , Grigorenko Aleksandr , May Paul , Kastango Nicholas , Wagner Isaac , Caroline Aryeh , Kris Mark G. 
Published: June 2019

PURPOSEElectronic medical records (EMRs) are a vast resource of potentially mineable data that can be used to complement and extend clinical trials. Extracting and analyzing EMR data are impeded by technical complexities associated with large, multiformat databases. We sought to develop and validate a framework that would overcome the difficulties associated with EMR data and create a simple, portable, and expandable system to better use this resource.MATERIALS AND METHODSAn Internet-accessible program was developed in Python that applied user-defined criteria to identify and extract patient data from Memorial Sloan Kettering databases. A Worker Application composed of individual modules was developed to identify each patient’s functional status, smoking status, and treatment classification. The validity of this approach was tested by identifying, extracting, and analyzing data from a patient cohort that paralleled a practice-changing, prospective, randomized phase III clinical trial performed at a different institution. We called this a synthetic clinical trial.RESULTSOur synthetic clinical trial identified and extracted data on a cohort of 281 patients with lung cancer who matched inclusion criteria and received their first treatment between October 2003 and July 2010. The data extraction modules were precise and accurate, with F-measures greater than 0.98. Results were similar in directionality and magnitude to the chosen comparator clinical trial.CONCLUSIONOur framework offers an accurate and user-friendly interface for identifying and extracting EMR data that can be used to create synthetic clinical trials. Additional studies are needed to validate this approach in other patient cohorts, replicate our findings, and leverage this methodology to improve patient care and accelerate drug development.
Recovery of the Hypothalamo-Pituitary-Adrenal Axis After Transsphenoidal Adenomectomy for Non–ACTH-Secreting Macroadenomas
Authors: Pofi Riccardo , Gunatilake Sonali , Macgregor Victoria , Shine Brian , Joseph Robin , Grossman Ashley B , Isidori Andrea M , Cudlip Simon , Jafar-Mohammadi Bahram , Tomlinson Jeremy W , Pal Aparna 
Published: June 2019

Abstract

Context
Secondary adrenal insufficiency is a potential complication of transsphenoidal adenomectomy (TSA). Most centers test recovery of the hypothalamo-pituitary-adrenal (HPA) axis after TSA, but, to our knowledge, there are no data predicting likelihood of recovery or the frequency of later recovery of HPA function.

Objective
To assess timing and predictors of HPA axis recovery after TSA.

Design
Single-center, retrospective analysis of consecutive pituitary surgeries performed between February 2015 and September 2018.

Patients
Patients (N = 109) with short Synacthen test (SST) data before and at sequential time points after TSA.

Main outcome measures
Recovery of HPA axis function at 6 weeks, and 3, 6, and 9 to12 months after TSA.

Results
Preoperative SST indicated adrenal insufficiency in 21.1% Among these patients, 34.8% recovered by 6 weeks after TSA. Among the 65.2% (n = 15) remaining, 13.3% and 20% recovered at 3 months and 9 to 12 months, respectively. Of the 29% of patients with adrenal insufficiency at the 6-week SST, 16%, 12%, and 6% subsequently recovered at 3, 6, and 9 to 12 months, respectively. Preoperative SST 30-minute cortisol, postoperative day 8 cortisol, and 6-week postoperative SST baseline cortisol levels above or below 430 nmol/L [15.5 μg/dL; AUC ROC, 0.86]; 160 nmol/L (5.8 μg/dL; AUC ROC, 0.75); and 180 nmol/L (6.5 μg/dL; AUC ROC, 0.88), were identified as cutoffs for predicting 6-week HPA recovery. No patients with all three cutoffs below the threshold recovered within 12 months after TSA, whereas 92% with all cutoffs above the threshold recovered HPA function within 6 weeks (OR, 12.200; 95% CI, 5.268 to 28.255).

Conclusion
HPA axis recovery can occur as late as 9 to 12 months after TSA, demonstrating the need for periodic reassessment of patients who initially have SST-determined adrenal insufficiency after TSA. Pre- and postoperative SST values can guide which patients are likely to recover function and potentially avoid unnecessary lifelong glucocorticoid replacement.
Impaired 11β-Hydroxysteroid Dehydrogenase Type 2 in Glucocorticoid-Resistant Patients
Authors: Vitellius Géraldine , Delemer Brigitte , Caron Philippe , Chabre Olivier , Bouligand Jérôme , Pussard Eric , Trabado Séverine , Lombes Marc 
Published: June 2019

Abstract

Context
Six patients carrying heterozygous loss-of-function mutations of glucocorticoid (GC) receptor (GR) presented with hypercortisolism, associated with low kalemia, low plasma renin, and aldosterone levels, with or without hypertension, suggesting a pseudohypermineralocorticism whose mechanisms remain unclear. We hypothesize that an impaired activity of the 11β-hydroxysteroid dehydrogenase type 2 (11β-HSD2; encoded by the HSD11B2 gene), catalyzing cortisol (F) inactivation, may account for an inappropriate activation of a renal mineralocorticoid signaling pathway in these GC-resistant patients.

Objective
We aim at studying the GR-mediated regulation of HSD11B2.

Design
The HSD11B2 promoter was subcloned and luciferase reporter assays evaluated GR-dependent HSD11B2 regulation, and 11β-HSD2 expression/activity was studied in human breast cancer MCF7 cells, endogenously expressing this enzyme.

Results
Transfection assays revealed that GR transactivated the long (2.1-kbp) HSD11B2 promoter construct, whereas a defective 501H GR mutant was unable to stimulate luciferase activity. GR-mediated transactivation of the HSD11B2 gene was inhibited by the GR antagonist RU486. A threefold increase in HSD11B2 mRNA levels was observed after dexamethasone (DXM) treatment of MCF7 cells, inhibited by RU486 or by actinomycin, supporting a GR-dependent transcription. Chromatin immunoprecipitation further demonstrated a DXM-dependent GR recruitment onto the HSD11B2 promoter. 11β-HSD2 activity, evaluated by the cortisone/F ratio, quantified by liquid chromatography/tandem mass spectrometry, was 10-fold higher in the supernatant of DXM-treated cells than controls, consistent with a GR-dependent stimulation of 11β-HSD2 catalytic activity.

Conclusion
Collectively, we demonstrate that 11β-HSD2 expression and activity are transcriptionally regulated by GR. In the context of GR haploinsufficiency, these findings provide evidence that defective GR signaling may account for apparent mineralocorticoid excess in GC-resistant patients.
Leonidas Karakatsanis, Turkish-Greek Relations: Rapprochement, Civil Society and the Politics of Friendship
Authors: Derisiotis Anthony 
Published: June 2019

Review of Leonidas Karakatsanis, Turkish-Greek Relations: Rapprochement, Civil Society and the Politics of Friendship. London and New York: Routledge, 2014. xxi + 283 pp.
Examining the Extended Parallel Process Model for communicating about cardiovascular disease to an at-risk population utilising a think aloud methodology
Authors: Moylett Sinead , Hevey David 
Published: June 2019

Background:Previous research has raised a number of questions about the core propositions of the Extended Parallel Process Model (EPPM). Very few previous examinations of the model have included qualitative assessments.Methods:The current study utilised a mixed method approach to experimental test EPPM-based threat-to-efficacy ratios in health risk messages about CVD and the associated health behaviours among older adults (60+ years) who would be at an alleviated risk of CVD. The current focus is on the qualitative aspect of this assessment and utilised a think aloud methodology in order to gain greater insight into participants’ thinking and problem-solving processes when presented with EPPM-based communications about cardiovascular disease (CVD). 24 participants (4 per group; Female = 14; Age,M= 74.38,SD= 7.16) were randomly assigned to one of six EPPM threat-to-efficacy ratio CVD message groups.Results:A thematic analysis was conducted, and the important themes were those of different threat perceptions for varying CVD manifestations (heart disease versus stroke), and the role of comparative (versus personal) threat and efficacy perceptions for all participants. The difference between threat appraisals for stroke versus other CVD manifestations was a novel finding.Conclusions: For the EPPM and other theories of health risk and decision-making, the impact of comparative risk and social examples for individual threat and efficacy perceptions needs to be counted.
Livelihood Transformations of the Orang Rimba as Tacit Resistance in the Context of Deforestation
Authors: Prasetijo Adi 
Published: June 2019

The Orang Rimba are one of the hunter-gatherer groups remaining in Sumatra. Their livelihoods are based on managing the forest in which they live. They follow the tradition of natural resource management that is based on non-wood forest products (Ø. Sandbukt, 1988). State policies that focus on economic development since the New Order regime have ultimately affected their lives. Many forest areas and the territories in which they practice nomadism are being converted into plantations, agricultural land, and residential development, which all contribute to the condition of deforestation. State policy also does not favor the Indigenous people. If we look at spatial development in Jambi over the past 25 years, the allocation of land for other uses, such as residences, estates, and physical development, has shown little regard for the indigenous people who live in the forest region. Orang Rimba have no area left in which to roam and continue their lives as traditional hunters and gatherers. Cut off from their cultural roots, they cannot any longer live in accordance with their culture and tradition. As a group, they suffer both physical and socio-cultural displacement. Orang Rimba react to this situation in different ways to transform their livelihoods into a survival mode in order to face the everyday reality of accelerated deforestation. Under these new circumstances, Orang Rimba livelihoods can be regarded as ‘tacit resistance’ or, to use James Scott’s term, a ‘hidden transcript’ of the weapons of the weak(Scott, 1985). They use a variety of ways to make a living, both economic and sociocultural. NGOs also have a prominent role to support the Orang Rimba. NGOs assist the Orang Rimba to put themselves in a position parallel to other communities. This paper will look at the impact of Jambi spatial policies that have been unfavorable to Indigenous People and how the Orang Rimba respond to them
Bissu: Keistimewaan Gender dalam Tradisi Bugis
Authors: Suliyati Titiek 
Published: June 2019

As one of many ethnics in Indonesian, Bugis ethnic posses much uniqness compared to other Indonesian ethnics. Bissu as one of Bugis traditions is gender spisification that does not exist either in man or woman. Indonesian society generally acknowledge man and woman gender. This is different from gender qualification in Bugis society. In Bugis society gender has five categories: Oroane is man either physically or its role in every day live; makkunrai is a woman either physically or its nature as woman; calalai is a woman behaves as a man; calabai is a man behaves as a woman. Bissu is a group does not belong to the four above genders. The performance of Bissu is very special because of its costume. This group wear neither man or woman costumes.Traditional Bugis society consider Bissu as combination of the four above gender. Not all Calalai or Calabai can become a Bissu. Being a Bissu is gods gift. Bugis society respect higly to Bissu, because Bissu has knowledge about tradition, family root, social life, traditional mystical cure and the life of gods. Bissu is able to communicate with the deaths and gods. Because Bisu is considered as a holy creature, they have an exlusive life. At present, the number and activities of Bissu is decreasing because of the changing of the government sytem: from monarchy to republic, the DI/TII rebellion in 1950, that wanted to abolish Bissu existence due to the abuse of Islamic law.
Evaluation of Quality of Life in Terms of Sinonasal Symptoms in Children with Cystic Fibrosis
Authors: Hassanzad Maryam , Derakhshan Kourosh Fakhimi , Ghaffaripour Hosseinali , Naeini Ali Safavi , Emami Habib , Velayati Ali Akbar 
Published: June 2019

AbstractObjectiveSinusitis is a common complaint in children with cystic fibrosis. However, the actual prevalence of chronic rhinosinusitis and its effect on the quality of life of children have not been well considered. Therefore, the objective of this study was to determine the effect of sinonasal quality of life in children with cystic fibrosis.Materials and methodsThis study was a diagnostic study performed on 80 children with cystic fibrosis ranging from 2 to 20 years old, who were referred to the cystic fibrosis clinic of Masih Daneshvari Hospital from 2017–2018. The questionnaires used in this study were chronic rhinosinusitis screening questionnaire based on the European task force and the evaluation of the sinonasal quality of life was based on the SN-5 survey.ResultsOf the 80 patients with fibrosis from 2 to 20 years old who were recruited in the study, 41 patients were female (51.3%) and 39 were male (48.8%). In 61 cases (76.3%), there was no chronic rhinosinusitis and 19 cases (23.8%) had chronic rhinosinusitis. The mean SN-5 score in 19 patients with chronic rhinosinusitis was 3.4105 and the mean score of patients without rhinosinusitis was 1.8426, with a P-value of 0.000. The mean SN-5 score was significant between the two groups. In patients with nasal congestion, there was a significant difference in quality of life factors such as sinus infection, nasal obstruction, and allergy symptoms (P<0.001). In patients with facial pain, there was a significant difference in quality of life factors such as sinus infection, nasal obstruction, allergic symptoms, and physical activity limitation (P <0.001). There was also a significant difference in the quality of life factors such as sinus infection, nasal obstruction, and allergy symptoms in patients with postnasal drip (P <0.001).ConclusionIn children with cystic fibrosis, the quality of life of sinonasal has a significant relationship with absence of chronic rhinosinusitis. This study showed that children with chronic renosinusitis have significantly lower quality of sinonasal life than children with chronic rhinosinusitis. The results demonstrated that quality of life scores in sinus infections, nasal obstruction, and allergy symptoms were significantly higher in patients with chronic rhinosinusitis than in those without chronic rhinosinusitis. The findings of this study are important for improving children’s health related quality of life, as it leads to promoting communication between the patient and the health care provider, identifying overlooked problems, monitoring the progress of the disease and the burden of treatment, and promoting interventions in the daily life of patients.
Effect of Anode Gas Diffussion Layer Thickness and Porosity on the Performance of Passive Direct Methanol Fuel Cell
Authors: Boni Muralikrishna , Srinivasa Rao S , Naga Srinivasulu G , Narayana Ch Venkata 
Published: June 2019

Abstract
Fuel cells are finding wide range of applications from small capacity cells used for portable electronic devices to large capacity stacks for automobile applications. Among the different types of fuel cells, passive Direct methanol fuel cell (DMFC) has many advantages because of its simplicity. This paper presents the effect of Anode Diffusion Layer (ADL) thickness and its porosity on the performance of a passive DMFC. A one-dimensional, non-isothermal model is developed in MATLAB environment for exploring the complex physicochemical phenomena taking place inside the passive DMFC, by considering both heat and mass transfer effects. Modeling studies have been carried out by varying the ADL thickness from 0.1 mm to 0.6 mm, and the ADL porosity from 0.3 to 0.8. The concentration distribution of methanol, water and oxygen inside the cell have been predicted and, the crossover of methanol and water across the membrane have also been estimated. It is observed that increase in thickness of the ADL decreases the methanol corss over. Further, the effect of ADL thickness and porosity on the anodic overpotential and cathodic overpotential have been estimated. It was observed that increase in ADL thickness as well as its porosity increase the overpotentials.
Extended Mittag-Leffler function and associated fractional calculus operators
Authors: Choi Junesang , Parmar Rakesh K. , Chopra Purnima 
Published: June 2019

Abstract
Motivated mainly by certain interesting recent extensions of the generalized hypergeometric function [H. M. Srivastava, A. Çetinkaya and I. Onur Kıymaz,
A certain generalized Pochhammer symbol and its applications to hypergeometric functions,
Appl. Math. Comput. 226 2014, 484–491] by means of the generalized Pochhammer symbol, we introduce here a new extension of the generalized Mittag-Leffler function.
We then systematically investigate several properties of the extended Mittag-Leffler function including some basic properties, Mellin, Euler-Beta, Laplace and Whittaker transforms.
Furthermore, certain properties of the Riemann–Liouville fractional integrals and derivatives associated with the extended Mittag-Leffler function are also investigated. Some interesting special cases of our main results are pointed out.