bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artificial intelligence-based analysis of lower limb muscle mass and fatty degeneration in patients with knee osteoarthritis and its correlation with Knee Society Score
Authors: Kono Kohei , Kinoshita Tomofumi , Soufi Mazen , Otake Yoshito , Masaki Yuto , Uemura Keisuke , Kutsuna Tatsuhiko , Hino Kazunori , Miyamoto Takuma , Tanaka Yasuhito , Sato Yoshinobu , Takao Masaki 
Published: November 2024

Abstract
Purpose
Lower-limb muscle mass reduction and fatty degeneration develop in patients with knee osteoarthritis (KOA) and could affect their symptoms, satisfaction, expectation and functional activities. The Knee Society Scoring System (KSS) includes patient reported outcome measures, which is widely used to evaluate the status of knee function of KOA. This study aimed to clarify how muscle mass and fatty degeneration of the lower limb correlate with the KSS in patients with KOA.

Methods
This study included 43 patients with end-stage KOA, including nine males and 34 females. Computed tomography (CT) images of the lower limb obtained for the planning of total knee arthroplasty were utilized. Ten muscle groups were segmented using our artificial-intelligence-based methods. Muscle volume was standardized by dividing by their height squared. The mean CT value for each muscle group was calculated as an index of fatty degeneration. Bivariate analysis between muscle volume or CT values and KSS was performed using Spearman’s rank correlation test. Multiple regression analysis was performed, and statistical significance was set at p  < 0.05.

Results
Bivariate analysis showed that the functional activity score was significantly correlated with the mean CT value of all muscle groups except the adductors and iliopsoas. Multiple regression analysis revealed that the functional activities score was significantly associated with the mean CT values of the gluteus medius and minimus muscles and the anterior and lateral compartments of the lower leg (β = 0.42, p = 0.01; β = 0.33, p = 0.038; and β = 0.37, p = 0.014, respectively).

Conclusion
Fatty degeneration, rather than muscle mass, in the lower-limb muscles was significantly associated with functional activities score of the KSS in patients with end-stage KOA. Notably, the gluteus medius and minimus and the anterior and lateral compartments of the lower leg are important muscles associated with functional activities.
Frühe feministische Petitionen aus der Schweiz
Authors: Schröter Juliane 
Published: November 2024

ZusammenfassungIn diesem Beitrag werden die ältesten heute noch bekannten und auffindbaren Petitionen analysiert, mit denen Frauen in der Schweiz versucht haben, ihre Lebensbedingungen zu verbessern. Sechs Petitionen, die zwischen 1846 und 1872 entstanden sind, werden in den Dimensionen Lexik, Sprechakte und Argumentationen mit Blick auf Bezeichnungen von Personen, für die Partei ergriffen wird, Zielbezeichnungen, politische Bitten bzw. Forderungen, Standpunkte sowie wiederkehrende Prämissen und Argumente untersucht. Die Ergebnisse deuten darauf hin, dass Frauen erst in den 1870er Jahren im politischen Diskurs als klar benennbare Interessensgruppe relativ etabliert waren, dass die Frauenbewegungen in ihren ersten Anfängen noch keine politischen Forderungen sensu stricto stellten, dass ihre Petitionserfahrung und ihr Politikwissen zu Beginn noch nicht groß genug waren, um unklare, wechselnde und falsch adressierte Standpunkte zu verhindern, dass sie aber bereits auf ein Repertoire zentraler Argumente zurückgreifen konnten, die bis heute bekannt sind. Mit Hilfe der gewonnenen Ergebnisse werden am Ende des Beitrags diachrone Hypothesen zum Sprachgebrauch der Frauenbewegungen in der Schweiz aufgestellt, die von der zukünftigen Forschung überprüft werden könnten.
Burnout: a comprehensive review
Authors: Demerouti Evangelia 
Published: November 2024

AbstractBurnout has been the focus of extensive scientific research. The World Health Organization officially recognized burnout as an occupational phenomenon, defined as a syndrome resulting from chronic workplace stress that remains unmanaged and characterized by three dimensions: exhaustion, cynicism, and inefficacy. Existing literature highlights limitations in current measurement instruments for diagnostic purposes. These tools often yield scores that overlap with other conditions such as fatigue, anxiety, and depression. Chronic exposure to high job demands and low job resources emerges as the primary trigger for burnout. While individual characteristics (such as neuroticism) may increase susceptibility, specific personality traits associated with higher risk remain unclear. Burnout has adverse effects on both individuals and organizations. Typical interventions focus on stress relief and coping strategies to manage high job demands, but their effectiveness diminishes over time. Evidence from organizational interventions suggests that improving employees’ working conditions can reduce burnout risk. Combined interventions offer promise by creating a healthy work environment while empowering employees to handle occasional stress. Social partners should advocate for support in researching burnout, aiming for a clear diagnosis, effective treatment, and preventive measures to mitigate psychosocial risks in the workplace.Practical Relevance: The findings of this article highlight the importance of addressing both job demands and job resources to mitigate burnout in organizational settings. Implementing interventions that improve working conditions and provide adequate support can significantly reduce burnout risk and enhance employee well-being. Organizations should prioritize creating a healthy work environment and empowering employees with the necessary resources to manage workload effectively.
Information geometry of the Otto metric
Authors: Ay Nihat 
Published: November 2024

AbstractWe introduce the dual of the mixture connection with respect to the Otto metric which represents a new kind of exponential connection. This provides a dual structure consisting of the mixture connection, the Otto metric as a Riemannian metric, and the new exponential connection. We derive the geodesic equation of this exponential connection, which coincides with the Kolmogorov forward equation of a gradient flow. We then derive the canonical contrast function of the introduced dual structure.
Association of oral frailty with falls in long-term care residents
Authors: Puranen Taija , Hiltunen Kaija , Pitkälä Kaisu H. , Roitto Hanna-Maria , Mäntylä Päivi , Saarela Riitta K. T. 
Published: November 2024

Abstract

Purpose
We investigated the relationship between oral frailty (OFr) and falls among long-term care residents.

Methods
Residents (N = 254, mean age 84 y, 79% women) participated in this longitudinal cohort study in 2018–2021. OFr was defined by six signs. Demographics, diagnoses, and medications were retrieved from the medical records. Frailty phenotype, sarcopenia and disability were assessed. Number of falls was collected from medical records over 12 months following baseline assessment.

Results
Of participants, 35% fell during follow-up. Of the fallers, 28% were bedridden or needed a wheelchair; among non-fallers, this figure was 73%. In logistic regression analysis after adjusting for age, sex, BMI, stroke, dementia, diabetes, coronary heart disease, number of medications, mobility, walking speed and sarcopenia, OFr did not predict falls (OR for severe OFr 0.13 (95% CI 0.01—1.27). Male sex predicted falls.

Conclusions
No association was found between severe OFr and falls over a 12-month follow-up.
Exploring the power of natural outdoor spaces in enhancing early childhood practitioners’ wellbeing
Authors: Geuens Nina , Willockx Dietlinde , Janssen Jeroen 
Published: November 2024

AbstractWhile there is growing consensus on the benefits of natural outdoor play environments for children, the impact of such spaces on the wellbeing of early childhood practitioners remains unknown. Using an exploratory qualitative design, this study unraveled the positive outcomes of greening outdoor spaces in childcare centers in Flanders (Belgium) and the challenges that it may encompass. Eleven in-depth interviews were conducted with professionals who were recently involved in such transformations. Through a thematic analysis seven outcomes were identified: (1) reduced workload, (2) calmer children and less conflicts, (3) more job fulfillment, (4) a sense of peace, (5) a place to enjoy, (6) more little pleasures, and (7) more chances for meeting up with colleagues. Challenges arose mainly in relation to (1) health and safety concerns, (2) transitions, (3) resources, and (4) team spirit. The results indicate that the establishment of natural outdoor spaces in childcare centers can benefit practitioners’ wellbeing in several ways. As such, this study calls for a broader understanding of the importance of green experiences in early childhood education and care. Our insights should be taken into consideration when designing natural outdoor spaces for childcare centers as well as in developing personnel policies on staff wellbeing. Further research is needed, however, to determine the generalizability of research findings and the extent and kind of green experience that is necessary to obtain the positive outcomes.
Human Dynamics Research in GIScience: challenges and opportunities
Authors: Shaw Shih-Lung , Ye Xinyue , Goodchild Michael , Sui Dan 
Published: November 2024

AbstractThe Symposium on Human Dynamics Research, first organized at the 2015 AAG Meeting in Chicago, celebrated its 10th anniversary at the 2024 AAG Meeting in Honolulu, marking a decade of transformative advancements in the field. Over the past decade, the focus of human dynamics research has shifted from traditional spatial-temporal analyses to sophisticated modeling of human behavior in a hybrid physical-virtual world. This evolving field now examines the intricate interdependencies between physical and digital environments, addressing critical issues such as urban resilience, public health, social equity, and community sustainability. The symposium emphasized the growing importance of interdisciplinary collaboration, advanced data-driven analytical platforms, and innovative theoretical frameworks to better understand human interactions across these spaces. As human dynamics continue to shape global urban systems, these advancements are pivotal for future research and real-world problem-solving, offering novel insights into the interconnectedness of mobility, technology, and societal well-being in a rapidly changing world.
Effect of synthesis temperature on the properties and photocatalytic performance of peroxo-titanate nanotubes prepared by bottom-up synthesis method
Authors: Han Do Hyung , Park Hyunsu , Goto Tomoyo , Cho Sunghun , Seo Yeongjun , Kondo Yoshifumi , Nishida Hisataka , Sekino Tohru 
Published: November 2024

AbstractThe alkaline treatment synthesis of titania/titanate nanotubes (TNTs) requires highly concentrated alkaline solutions (≥ 10 mol/L), which pose environmental and productivity limitations. In contrast, a bottom-up synthesis method for peroxo-titanate nanotubes (PTNTs) has been developed. This method offers two advantages: it can synthesize materials using low-concentration alkaline solutions (1.5 mol/L) and produce photocatalytic materials that are responsive to visible light. In general, the higher the crystallinity of a catalyst, the better its properties. However, PTNTs synthesized at temperatures close to their boiling point (around 100 °C) exhibit low crystallinity. This study hypothesizes a hydrothermal synthesis method at higher temperatures will enhance the crystallinity and photocatalytic performance of PTNTs, synthesizing them at temperatures ranging from 120 to 200 °C using a method capable of exceeding the boiling point. Higher synthesis temperatures resulted in improved morphological and crystallographic properties of the PTNTs. However, the formation of peroxo-bonding, crucial for visible light responsiveness, decreased. Nevertheless, peroxo-bonding formation was still achievable at the highest temperature of 200 °C, and the sample exhibited the best Rhodamine B (Rh B) photodegradation performance under visible light due to its enhanced specific surface area and crystallinity. This study highlights the novelty and environmental significance of hydrothermally synthesized PTNTs as superior photocatalysts by optimizing the synthesis temperature while using lower concentration alkaline solutions.
Population-based cross-sectional survey of cervical cancer screening prevalence and socio-demographic correlates in Bangladeshi women
Authors: Khan Mohammad Jobair , Kannan Priya , Sayma  , Winser Stanley John 
Published: November 2024

Abstract
Background
Cervical cancer, albeit preventable, is the second-most deadly gynecological cancer in developing nations. Little is known about cervical cancer among Bangladeshi women. This study aims to estimate the prevalence of cervical cancer screening and demographic correlates to identify potential variabilities in screening rates among different demographic groups and regions.

Methods
This study used secondary data from the WHO STEPS 2018 Survey. We used Bayesian regression to perform the bivariate analyses between the outcome and each explanatory factor, as it generates more acceptable results and improves parameter estimates. The top-ranked socio-demographic factors were identified using a two-step cluster analysis. This method determines the relevance of predictor variables and automatically establishes the number of clusters.

Results
The prevalence of Bangladeshi women who had ever been screened for cervical cancer was 6.2%. In the adjusted model, women with the following socio-demographic factors had a higher likelihood of developing cervical cancer: being 18–29 years old (AOR = 3.3, 95% CI: 0.24, 15.27) or 45–59 years old (AOR = 2.8, 95% CI: 1.22, 6.0), currently married (AOR = 2.3, 95% CI: 1.36, 3.70), and employed (AOR = 2.4, 95% CI: 1.40, 4.06). Women in the Barisal division were found to have higher odds of being screened for cervical cancer (AOR = 21, 95% CI: 0.66, 121.97). Cluster analysis found residence status predisposes women to cervical cancer screening.

Conclusion
There is a significant potential for substantial reductions in the burden of cervical cancer in Bangladesh by strengthening the application of cervical cancer screening. Future studies should examine how socioeconomic status, culture, and healthcare access affect cervical cancer screening trends for different divisions in Bangladesh. An independent national cancer registry is urgently needed to evaluate screening trends and outcomes.
Subthalamic nucleus deep brain stimulation modulates speech graphs in patients with Parkinson’s disease
Authors: Zhang Guanyu , Xiao Haoyun , Ma Jinghong , Lang Liqin , Wu Jianjun , Ye Zheng 
Published: November 2024

AbstractGraph theory enables a direct quantification of topological properties of any arbitrary network. Its application in neuroscience has unveiled topological changes of brain networks associated with various neurodegenerative diseases. This study used the graph theory to understand speech deficits in patients with Parkinson’s disease (PD). In particular, this study investigated the effect of subthalamic nucleus deep brain stimulation (STN-DBS) on the topology of speech graphs. Sixty patients with PD completed a standard semantic fluency test with DBS switched ON and OFF. A control group of sixty matched nonsurgical PD patients completed the test once. All verbal responses were recorded, transcripted, and transformed into directed speech graphs. Volumes of tissue activated (VTA) were estimated for three STN subregions, including sensorimotor, associative, and limbic parts. First, the patients with DBS OFF produced smaller and denser speech graphs than nonsurgical patients, showing fewer nodes, higher density, shorter diameter, and shorter average shortest path. Second, DBS partially reversed the effect of surgery, leading to larger and sparser speech graphs with more nodes, lower density, longer diameter, and longer average shortest path (ON versus OFF). Third, however, the left associative VTA negatively correlated with the DBS-induced diameter and average shortest path changes (ON versus OFF), suggesting that the patients with greater left associative STN stimulation tended to produce smaller and denser speech graphs. This study demonstrates that STN-DBS can partially restore the topological structure of speech graphs in PD patients. However, stimulating the left associative STN appears to disrupt speech graphs.
Bayesian recalibration ofPlanckgalaxy cluster scaling relations including relativistic Sunyaev-Zel’dovich corrections
Authors: Perrott Yvette 
Published: November 2024

AbstractWe investigate the impact of relativistic SZ corrections onPlanckmeasurements of massive galaxy clusters, finding that they have a significant impact at the$\approx$5–15% and up to$\approx$3$\sigma$level. We investigate the possibility of constraining temperature directly from these SZ measurements but find that only weak constraints are possible for the most significant detections; for most clusters, an external temperature measurement is required to correctly measure integrated Compton-y. We also investigate the impact of profile shape assumptions and find that these have a small but non-negligible impact on measured Compton-y, at the$\approx$5% level. Informed by the results of these investigations, we recalibrate thePlanckSZ observable-mass scaling relation, using the updated NPIPE data release and a larger sample of X-ray mass estimates. Along with the expected change in the high-mass end of the scaling relation, which does not impactPlanckmass estimation, we also find hints of a low-mass deviation, but this requires better understanding of the selection function in order to confirm.
Causal associations of tea consumption on risk of pancreatic adenocarcinoma and the mediating role of vascular endothelial growth factor D levels
Authors: Ouyang Yonghao , Zhou Beini , Chu Lihua , Chen Xin , Hao Qiang , Lei Jiajia 
Published: November 2024

AbstractTea is one of the most widely consumed beverages in the world. However, the association between tea and risk of pancreatic adenocarcinoma remains controversial. This study aimed to investigate the causal relationship between tea consumption and risk of pancreatic adenocarcinoma and to explore their mediating effects. The two-sample Mendelian randomisation (MR) analysis showed an inverse causal relationship between tea intake and pancreatic adenocarcinoma (OR: 0·111 (0·02, 0·85), P < 0·04). To examine the mediating effects, we explored the potential mechanisms by which tea intake reduces the risk of pancreatic adenocarcinoma. Based on the oral bioavailability and drug-like properties in Traditional Chinese Medicine Systems Pharmacology database, we selected the main active ingredients of tea. We screened out the fifteen representative targeted genes by Pharmmapper database, and the gene ontology enrichment analysis showed that these targeted genes were related to vascular endothelial growth factor (VEGF) pathway. The two-step MR analysis of results showed that only VEGF-D played a mediating role, with a mediation ratio of 0·230 (0·066, 0·394). In conclusion, the findings suggest that VEGF-D mediates the effect of tea intake on the risk of pancreatic adenocarcinoma.
Neogene Hydrothermal Fe‐ and Mn‐Oxide Mineralization of Paleozoic Continental Rocks, Amerasia Basin, Arctic Ocean
Authors: Hein James R. , Mizell Kira , Gartman Amy 
Published: November 2024

AbstractRocks dredged from water depths of 1,605, 2,500, 3,300, and 3,400 m in the Arctic Ocean included Paleozoic continental rocks pervasively mineralized during the Neogene by hydrothermal Fe and Mn oxides. Samples were recovered in three dredge hauls from the Chukchi Borderland and one from Mendeleev Ridge north of Alaska and eastern Siberia, respectively. Many of the rocks were so pervasively altered that the protolith could not be identified, while others had volcanic, plutonic, and metamorphic protoliths. The mineralized rocks were cemented and partly to wholly replaced by the hydrothermal oxides. The Amerasia Basin, where the Chukchi Borderland and Mendeleev Ridge occur, supports a series of faults and fractures that serve as major zones of crustal weakness. We propose that the stratabound hydrothermal deposits formed through the flux of hydrothermal fluids along Paleozoic and Mesozoic faults related to block faulting along a rifted margin during minor episodes of Neogene tectonism and were later exposed at the seafloor through slumping or other gravity processes. Tectonically driven hydrothermal circulation most likely facilitated the pervasive mineralization along fault surfaces via frictional heating, hydrofracturing brecciation, and low‐ to moderate temperature Fe‐ and Mn‐rich hydrothermal fluids, which mineralized the crushed, altered, and brecciated rocks.
Biofilm Growth in Porous Media Well Approximated by Fractal Multirate Mass Transfer With Advective‐Diffusive Solute Exchange
Authors: Wang Jingjing , Carrera Jesús , Saaltink Maarten W. , Petchamé‐Guerrero Jordi , Herrera Graciela S. , Valhondo Cristina 
Published: November 2024

AbstractBiofilm growth in porous media changes not only the hydrodynamic properties of the medium (reduction in porosity and permeability, and increase in dispersivity), but also the transport itself (breakthrough curves display increasingly fast first arrivals and long tails). These features are well reproduced by multicontinuum models (Multi‐Rate Mass Transfer, MRMT) which can be used to describe reactive transport in heterogeneous porous media and facilitate the simulation of reactions that are localized within biofilms. Here, we present a conceptual and numerical model of biochemical reactive transport with dynamic biofilm growth based on MRMT formulations. Mass exchange between mobile water and immobile biofilm aggregates is represented by a memory function, which simplifies definition of MRMT parameters. We successfully tested this model on two sets of laboratory data and found that (a) a basic model based on the growth of uniformly sized biofilm aggregates fails to reproduce laboratory tracer tests and rate of biofilm growth, while a fractal growth model, which we obtain by integrating the memory functions of biofilm aggregates with a power law distribution, does; (b) the biofilm memory function evolves as the biofilm grows; and (c) the early time portion of eluted volume tracer breakthrough curves are independent of flow rate, whereas the tail becomes heavier when the flow rate is decreased, which implies that both advection controlled and diffusion controlled mass exchange coexist in biofilms. These findings imply that porous media biofilms are essentially different from those developing in human tissues or open spaces.