bluuebunny/crossref_metadata_2025_split huggingface dataset:
Epidemiología de pacientes con Cáncer de Piel sometidos a Cirugía Micrográfica de Mohs en Solca-Guayaquil entre 2015 y 2017.
Authors: Carvajal Ayala María Fernanda , Vásquez María Lorena 
Published: July 2019

Introducción: El cáncer de piel es la segunda neoplasia más común en la población guayaquileña, se presenta predominantemente en áreas expuestas a luz solar. Los tipos más frecuentes son el carcinoma basocelular y el escamocelular. La técnica de cirugía micrográfica de Mohs pese a ser descrita hace varias décadas continua vigente en el tratamiento de este tipo de neoplasias. El objetivo del estudio es presentar una serie de casos sometidos a esta cirugía.
Métodos: El presente estudio observacional, fue realizado en el Instituto Oncológico Nacional “Dr. Juan Tanca Marengo” Solca-Guayaquil. Se revisaron historias clínicas de los períodos comprendidos de enero del 2015 a diciembre del 2017. Se seleccionaron casos de pacientes con neoplasias malignas de la piel, sometidos a cirugía micrográfica de Mohs. El tipo de muestreo fue no probabilístico de conveniencia. Las variables estudiadas fuero sexo, edad, diagnóstico anatomopatológico, localización de las lesiones y recidivas. Se utiliza estadística descriptiva.
Resultados: Se analizaron 153 pacientes con edad media de 71.9 ±12 años, el tipo histológico más frecuente fue el carcinoma basocelular nodular con 115 casos (75.16 %). Las lesiones se localizaron predominantemente en el dorso nasal 40 casos (26.14%) y en el ala nasal 17 casos (11.11%). Almomento de la intervención quirúrgica más de la mitad de las lesiones se encontraban en estadio 1 (58.1%). La técnica de cobertura empleada con mayor frecuencia fue el colgajo de rotación (49 %). No se registraron casos de recidiva posterior a la cirugía micrográfica de Mohs en los pacientes estudiados.
Conclusión: Las características epidemiológicas de cáncer de piel en la población de Guayaquil son similares a las reportadas en literatura internacional. Los pacientes sometidos a cirugía micrográfica de Mohs no presentaron recidiva en este reporte.
Eficacia de Resecciones Hepáticas por Metástasis de Origen Colorrectal
Authors: Panchana Egüez Guido , Macías Fernández Pamela , Zambrano Diego A , Lara Perlaza Luis Mauricio , Idrovo Murillo Luis , Panchana Coello Guido 
Published: July 2019

Introducción: El cáncer colorrectal (CCR) es la segunda neoplasia más común después del cáncer gástrico, y con frecuencia desarrolla metástasis hepática. Se presenta un estudio unicéntrico del abordaje quirúrgico, resultados y sobrevida pacientes sometidos a cirugía más tratamiento sistémico de metástasis hepáticas de CCR.
Métodos: Se realizó un estudio retrospectivo y descriptivo en el Instituto Oncológico del Ecuador de Solca- Guayaquil desde enero del 2015 a diciembre del 2018. Se incluyeron todos los pacientes del Servicio de Laparoscopía operados por cáncer colorrectal, como diagnóstico inicial, que durante sus controles periódicos presentaron metástasis hepáticas y fueron candidatos para tratamiento quirúrgico de metastasectomias, previa valoración con comités de tumores de tubo digestivo.
Resultados: La muestra final incluyó 6 pacientes a quienes se les pudo realizar metastasectomías hepáticas anatómicas y no anatómicas. La edad media fue 60 años, con predominio del sexo femenino (n=4, 66.6%). Las lesiones hepáticas se presentaron en un solo segmento hepático en el 66% a las que se les realizo resección total, y cuyas complicaciones presentadas fueron del 33 %, que se resolvieron durante la estancia hospitalaria. Un paciente recibió neoadyuvancia, y solo un paciente presentó metástasis metacrónica. La sobrevida es del 100% hasta la finalización del estudio.
Conclusión: Las decisiones multidisciplinarias sobre una oportuna indicación de metastasectomía hepática, disminuyen la morbimortalidad e incrementan la sobrevida de los pacientes con metástasis hepáticas de cáncer colorrectal.
CHEMOMETRICS ASSISTED VALIDATED HPLC METHOD DETECTING SEASONAL VARIANCES OF SECONDARY METABOLITES OF Camellia sinensis CONSIDERING THE ABIOTIC STRESSES
Authors: Bhandari Koushik , Goswami Tridib Kumar , De Baishakhi 
Published: July 2019

Climatic changes have great impact on the crops and agro-eco systems and such changes influences the concentration of secondary metabolites. IIT Kharagpur, India is a non-traditional tea growing zone where Tocklai Vegetative 25 variety was used as the research material. This study reports the development of a chemometrics assisted HPLC method validated as per ICH guidelines to explore the effect of seasonal variations in polyphenolics viz. catechins and methyl xanthenes like caffeine in fresh tea leaves and processed CTC black tea prepared from them. Further study was done on the variances amongst the concentration of secondary metabolites and abiotic stress factors. Good resolutions of secondary metabolites were obtained using 92% of 0.2% acetic acid and 8% of acetonitrile as the mobile phase, with a flow rate of 1 mL/ min, injection volume of 20 µl, PDA detector was set at 200-600 nm and chromatograms were recorded at 274 nm. Results of quantitative HPLC analysis have clearly shown that highest yield of catechins and caffeine were observed in fresh tea leaves plucked during spring (24.3ºC temperature and average rainfall of 34 mm) and also the processed black tea made from it, followed by tea leaves plucked during monsoon (28.8 ºC temperature and 282 mm rainfall) and processed black tea prepared from it. The lowest concentrations of secondary metabolites were found in leaves plucked during autumn (26.2 °C temperature and 132 mm rainfall) and the processed tea prepared from it. The developed quantitative HPLC method showed an inter day precision of 0.3, intraday precision of 0.2, repeatability value of 0.31, ruggedness value of 0.33 and robustness value of 0.2. Considering temperature and rainfall as abiotic stress factors, highest total polyphenolic content was obtained during spring and lowest in autumn. From our experimental findings, the fresh tea leaves of spring season and also the processed black tea prepared from it showed higher yield of catechins.
Non-Extensive Statistical Analysis of Energetic Particle Flux Enhancements Caused by the Interplanetary Coronal Mass Ejection-Heliospheric Current Sheet Interaction
Authors: Pavlos Evgenios G. , Malandraki Olga E. , Khabarova Olga V. , Karakatsanis Leonidas P. , Pavlos George P. , Livadiotis George 
Published: July 2019

In this study we use theoretical concepts and computational-diagnostic tools of Tsallis non-extensive statistical theory (Tsallis q-triplet: q s e n , q r e l , q s t a t ), complemented by other known tools of nonlinear dynamics such as Correlation Dimension and surrogate data, Hurst exponent, Flatness coefficient, and p-modeling of multifractality, in order to describe and understand Small-scale Magnetic Islands (SMIs) structures observed in Solar Wind (SW) with a typical size of ~0.01–0.001 AU at 1 AU. Specifically, we analyze ~0.5 MeV energetic ion time-intensity and magnetic field profiles observed by the STEREO A spacecraft during a rare, widely discussed event. Our analysis clearly reveals the non-extensive character of SW space plasmas during the periods of SMIs events, as well as significant physical complex phenomena in accordance with nonlinear dynamics and complexity theory. As our analysis also shows, a non-equilibrium phase transition parallel with self-organization processes, including the reduction of dimensionality and development of long-range correlations in connection with anomalous diffusion and fractional acceleration processes can be observed during SMIs events.
PENGARUH PROFITABILITAS, LEVERAGE DAN UKURAN PERUSAHAAN TERHADAP NILAI PERUSAHAAN
Authors: Rachmawati Dwi , Pinem Dahlia Br 
Published: July 2019

This study was conducted to examine the effect of Profitability, Leverage and Firm Size on Firm Value at the Company's anufacturing base and chemical industry sectors listed in Indonesia Stock Exchange during the years 2013 to 2014. The population in his study amounted to 55 companies manufacturing industrial ector basic and chemical contained in the Indonesia Stock Exchange during 2013 to 2014. Samples were obtained in this study of 52 samples selected by purposive sampling method. After outlier data, which eventually resulted 48 samples to be analyzed and tested. Data were tested using multiple linear regression method. These esults showed that: Provitability significant positive effect on firm value, Leverage not significant effect on firm value and Firm Size positive effect on firm value.
PENGARUH KOMITMEN PROFESIONAL, LOCUS OF CONTROL, KESERIUSAN PELANGGARAN DAN SUKU BANGSA TERHADAP INTENSI WHISTLEBLOWING (Studi Empiris pada Pemerintahan Daerah DKI Jakarta)
Authors: Ridho Muhammad Sidqi , Rini Rini 
Published: July 2019

The purpose of this study was to examine the influence of professional commitment,locus of control, seriousness of wrongdoing and ethnic group on whistleblowingintentions. The respondents in this research is financial staff in working units of local government (SKPD) DKI Jakarta. The sample in this research were 39 financial staff in 7 working unit of local government (SKPD) DKI Jakarta. The method of determining the sample uses convenience sampling method. Methods of analysis to test the hypothesis is multiple regression analysis. The results showed that the seriousness of wrongdoing affect the whistleblowing intentions. However, professional commitment, locus of control and ethnic group have no effect on whistleblowing intentions.
PENGARUH UKURAN PERUSAHAAN, PRICE EARNING RATIO DAN PROFITABILITAS TERHADAP NILAI PERUSAHAAN (Studi Empiris Pada Perusahaan Aneka Industri yang Terdaftar di Bursa Efek Indonesia tahun 2011 - 2015)
Authors: Henriansyah Galih , Dharmayuni Lita 
Published: July 2019

The purpose of this study is to know the influence ofFirm Size, Price Earning Ratio, and Profitability to Firm’s Value in various industry companies listed in Indonesia Stock Exchange 2011-2015. The data in this research is secondary data obtained through the company's annual financial statements for the financial period ended 2011-2015. This study used 7 samples of various industry companies listed on the Indonesia Stock Exchange. Each company is a company that has published its financial statements and complete data regarding the variables that will be examined during the period 2011-2015. The sample is taken by using purposive sampling, that the selection of members of the sample based on certain criteria. The results showed that the influence of Firm Size and Price Earning Ratio are positive and not significant to the Firm’s Value, and the influence of Profitability are positive and significant to on the Firm’s Value.
Implementasi Metode ODOA (One Day One Ayat) dalam Meningkatkan Kemampuan Menghafal al-Quran
Authors: Anwar Khoirul , Hafiyana Mufti 
Published: July 2019

Education has an important role in human life, without presence of human education will not develop properly. Implementation of education of children should be started early, especially religious education, because it will make strength of religion obtained. The duties of parents, teachers, and community is how guide of religion including in it teaches the al-Quran is still done, meaning that religious education should not be allowed to disappear. In order to maintain purity of Qur'an, in addition to do it by reading and understanding it, we also try to memorize it. At basic thought mentioned it, then formulated a focus on this research is planned memorizing activities of the al-Quran, the implementation of ODOA method (one day one ayat ) in improving the ability to memorize the al-Quran of students, and evaluation of memorizing activities of the al-Qur’an in Awar Awar NU Elementary School.
HUBUNGAN DUKUNGAN SUAMI DENGAN KUALITAS HIDUP PEREMPUAN MENOPAUSE
Authors: Wardani Desy Ayu 
Published: July 2019

Background: Menopause phase in women is the time when menstrual cycle stops which is followed by obvious psychological and physical changes and occurs 3 – 4 years. The psychological and physical changes in menopause women will affect the quality of their life. Therefore, supports from the close people, especially from their husbands are needed. Objective: This study aimed to find out the correlation between husband support and the life quality of menopause women. The type of this research was quantitative research using correlation analysis with cross sectional approach with the total of 126 respondents. The technique used in taking the sample was Purposive sampling technique. Chi Square test was used as the bivariate test. Finding: The research finding showed that p-value was 0.032. Conclusion: There was a correlation between husband support and the life quality of menopause women. Suggestion: There should be a follow-up research about the factors which affect the life quality of menopause women such as psychological, physical aspects, social relationship and environment surrounding the menopause women.
Close-in Sub-Neptunes Reveal the Past Rotation History of Their Host Stars: Atmospheric Evolution of Planets in the HD 3167 and K2-32 Planetary Systems
Authors: Kubyshkina D. , Cubillos P. E. , Fossati L. , Erkaev N. V. , Johnstone C. P. , Kislyakova K. G. , Lammer H. , Lendl M. , Odert P. , Güdel M. 
Published: July 2019

Abstract
Planet atmospheric escape induced by high-energy stellar irradiation is a key phenomenon shaping the structure and evolution of planetary atmospheres. Therefore, the present-day properties of a planetary atmosphere are intimately connected with the amount of stellar flux received by a planet during its lifetime, thus with the evolutionary path of its host star. Using a recently developed analytic approximation based on hydrodynamic simulations for atmospheric escape rates, we track within a Bayesian framework the evolution of a planet as a function of stellar flux evolution history, constrained by the measured planetary radius. We find that the ideal objects for this type of study are close-in sub-Neptune-like planets, as they are highly affected by atmospheric escape, and yet retain a significant fraction of their primordial hydrogen-dominated atmospheres. Furthermore, we apply this analysis to the HD 3167 and K2-32 planetary systems. For HD 3167, we find that the most probable irradiation level at 150 Myr was between 40 and 130 times solar, corresponding to a rotation period of

days. For K2-32, we find a surprisingly low irradiation level ranging between half and four times solar at 150 Myr. Finally, we show that for multi-planet systems, our framework enables one to constrain poorly known properties of individual planets.
Double-peaked [O i] Profile: A Likely Signature of the Gaseous Ring around KH 15D
Authors: Fang Min , Pascucci Ilaria , Kim Jinyoung Serena , Edwards Suzan 
Published: July 2019

Abstract
KH 15D is a well-known spectroscopic binary because of its unique and dramatic photometric variability. The variability is explained by a circumbinary dust ring, but the ring itself was never directly detected. We present a new interpretation of the double-peaked [O I] λ6300 profiles as originating from the hot disk surface of KH 15D. By modeling these profiles, we measure emitting radii between ∼0.5 and 5 au, basically a gaseous ring very similar in radial extent to the dust ring inferred from modeling the system’s photometric variability. We also discuss the possibility that external photoevaporation driven by ultraviolet photons from the nearby massive star HD 47887 has truncated the outer edge of the disk to the observed value.
Multi-wavelength Variability Properties of CGRaBS J0733+0456: Identifying a Distant Gamma-Ray Blazar at z = 3.01
Authors: Liao Neng-Hui , Dou Li-Ming , Jiang Ning , Wang Yi-Bo , Fan Yi-Zhong , Wang Ting-Gui 
Published: July 2019

Abstract
We report on Owens Valley Radio Observatory (OVRO), WISE, Swift and Fermi-LAT observations of the high redshift blazar CGRaBS J0733+0456, from which significant flux variations in radio and infrared (IR), as well as γ-ray domains, are detected. Particularly, the amplitude of long-term IR variation is over one order of magnitude, and the IR variability timescale can be constrained as short as a few hours in the source frame. The IR and γ-ray light curves are found to be rather similar, and the strong quasi-simultaneous IR and γ-ray flares are proven to be unique among the nearby γ-ray sources. This is the first time that a γ-ray blazar at redshift z ≥ 3 with multi-wavelength flux variations (flares) is identified. Broadband spectral energy distributions in different flux states are constructed and theoretically described. The γ-ray flares from some blazars as distant as redshift ∼5 are expected to be detectable for Fermi-LAT.
How Comets Work
Authors: Fulle M. , Blum J. , Rotundi A. 
Published: July 2019

Abstract
Two major questions regarding comets have been up to now far from any solution. (i) How is it possible that water-ice sublimation from the nucleus surface does not lead to an insulating crust, stopping every gas and dust ejection within a few days? (ii) How is it possible that the gas flow crossing the refractory surface crust ejects dust particles bonded by tensile strengths larger than tens of Pa when the perihelion gas pressure at the nucleus-coma interface is less than one Pa? We have developed a simple but rigorous analytical model, assuming that the cometary nucleus consists of agglomerates of ice and dust (“clusters”). As soon as the clusters become exposed to sunlight, gas diffusion from their inside leads to their dehydration. We find that (i) the gas diffusing from the interior to the surface of a sunlit cluster has a steep density gradient at the cluster surface, which blasts the cluster into particles of sizes larger than or equal to those actually observed by Rosetta dust instruments; (ii) the heat-conduction and diffusion timescales are much shorter than the dehydration timescale, ensuring that the described process prevents any dumping of the nucleus activity driven by water-ice sublimation from 4 au inbound to 4 au outbound; and (iii) the clusters are in fact cm-sized pebbles, so that a cometary nucleus made of pebbles is confirmed to be the only one consistent with cometary gas and dust activity, a process unexplained until now.
Longitudinal Health Status from Early Disease to Adulthood and Associated Prognostic Factors in Juvenile Idiopathic Arthritis
Authors: Tollisen Anita , Selvaag Anne Marit , Aasland Astrid , Lerdal Anners , Flatø Berit 
Published: July 2019

Objective.To describe the longitudinal health status from childhood to adulthood in patients with juvenile idiopathic arthritis (JIA), compare outcomes after 19 years with those of controls, and identify early predictors of physical functioning, pain, and physical health-related quality of life (HRQOL).Methods.Between 1995–2003, 96 patients with JIA (mean 6.1 ± 4.0 yrs, 67% female) were assessed within 18 months of diagnosis and every 6 months for the next 3 years with measures of JIA disease activity, physical functioning, pain, fatigue, and well-being. They were reassessed a mean of 18.9 ± 1.5 years later (mean age 25.1 ± 4.2 yrs) with measures of physical disability [Health Assessment Questionnaire–Disability Index (HAQ-DI)], pain, fatigue, well-being (visual analog scale), and physical and mental health-related quality of life (HRQOL; Medical Outcomes Study 12-item Short Form Health Survey, version 2).Results.During the first 3 years, physical disability improved (p < 0.001) and the proportion of patients reporting best possible well-being increased (p = 0.013), while pain and fatigue did not change. At 3- and 19-year followups, patients had similar levels of physical disability, well-being, and pain, but fatigue increased (p = 0.016) and the number of patients with HAQ-DI = 0 decreased (p = 0.001). After 19 years, patients had worse pain and physical HRQOL than controls (p < 0.001). Pain, active joints, and physical disability during the first 3 years were associated with more disability and pain and worse physical HRQOL after 19 years (p < 0.001–0.047).Conclusion.Patients with JIA reported similar physical functioning, well-being, and pain at 3- and 19-year followups, but more fatigue after 19 years. Patients also had worse health status than controls after 19 years. Pain, active joints, and physical disability were early predictors of unfavorable outcomes.
Quelle alternative philosophique et éducative au consumérisme contemporain ?
Authors: Kola Etienne 
Published: July 2019

Le marché est un paradigme central de l’intelligence économique contemporaine. Adopté par la plupart des États modernes, il a su opérer dans l’homme actuel une mutation spirituelle faisant de lui un fanatique de la consommation. La mécanique productiviste et consumériste ne traduit-elle pas une vision simplement matérialiste du vivre ? Ne contribue-t-elle pas à pervertir la liberté humaine ? N’est-elle pas un facteur de déséquilibre social et écologique ; un vecteur de corruption de l’éthique existentielle ? Les conceptions d’Emmanuel Levinas (1972) et de Luc Ferry (1996) de la transcendance incarnent des vertus pédagogiques dignes de révolutionner les mentalités actuelles vouées au culte du matérialisme. Organisée à partir d’une exploitation documentaire, la réflexion sera une analyse critique du consumérisme, avant d’être un plaidoyer en faveur de l’idée de transcendance telle que promue par Levinas et Ferry. Enfin, elle mettra en évidence la contribution du fait éducatif pour une reforme des mentalités.
Les accompagnateurs dans l’enseignement supérieur. Quel apprentissage suite aux affordances saisies dans un environnement multiculturel ?
Authors: Rached Patricia 
Published: July 2019

La présente étude s’inscrit dans une posture socioconstructiviste et adopte l’approche qualitative, se basant sur des entretiens semi-directifs menés auprès de 18 enseignants accompagnateurs relevant de six institutions de l’Université Saint-Joseph de Beyrouth (USJ). Les résultats révèlent que les accompagnateurs, capables de percevoir et de profiter des affordances offertes par ce milieu académique multiculturel, développent des compétences et des postures à travers les divers modes d’apprentissage mis en œuvre en situation professionnelle. L’étude débouche ainsi sur la mise en évidence d’un processus de causalité circulaire engendré par le processus d’accompagnement dans un contexte qui prescrit des objectifs académiques et qui induit des objectifs conjoints, suite au multiculturalisme.
L’écriture réflexive dans la relation tutorale avec des professeurs-documentalistes
Authors: Pfeffer-Meyer Victoria 
Published: July 2019

Cette étude est menée dans le cadre du tutorat de stagiaires professeurs documentalistes. Elle invite à réfléchir aux pratiques de formation dans la relation tutorale en utilisant l’écriture réflexive comme instrument de formation sur le lieu de stage. Nous avons élaboré trois situations d’apprentissages. Elles ont été réalisées, observées et analysées en référence au modèle de « contre transposition didactique » développé en didactique de l’information-documentation : la pratique des acteurs sert de support au travail d’écriture réflexive et détermine les objets d’apprentissage. Dans le processus réflexif, les stagiaires reviennent sur leur activité, ils mettent au jour et identifient des savoirs professionnels. La formalisation par le retour écrit sur l’action donne la possibilité d’une distanciation permettant au savoir de s’envisager dans une forme nouvelle. Ce procédé établit une trace, qui reflète une part du développement professionnel du praticien-apprenant.