bluuebunny/crossref_metadata_2025_split huggingface dataset:
Symbolic categories and the shaping of identity
Authors: Morales Jeremy 
Published: July 2019

Purpose
This paper aims to study the symbolic categorisations management accountants produce. It examines the categories they use to describe their work and analyses the meanings they attach to such categories. This aims at explaining how management accountants can follow a common occupational orientation despite the need to adjust their practices to the specificities of their local and organisational context. The author’s argument is that management accountants build symbolic categories to create a bridge between what they do and who they are. The author further argues that symbolic categories are needed to make sense of a practice in tension between a common aspirational orientation and heterogeneous local contexts.

Design/methodology/approach
This paper draws on a multiple case field study conducted by observation and interviews in a range of organisations.

Findings
This paper examines the empirical diversity of management accountants’ practices and perceptions through the symbolic categories they produce. The author finds that categorisation work constitutes a central mechanism to build a shared narrative despite heterogeneous situations. The author further shows that through symbolic categorisation work, a variety of activities ranging from bookkeeping through managerial support to hierarchical surveillance and challenge in the name of the shareholder are subsumed under stable labels. This, he argues, serves to mask financial accountability, shareholder orientation and hierarchical control behind a narrative of “support” and “partnership”.

Originality/value
This paper contributes to literature on management accountants’ identity by showing the central role played by symbolic categorisations. It also contributes to literature in accounting more generally by showing how symbolic categorisation work blurs the lines between “operational support” and “shareholder value creation”. The same words are used to refer to activities that managers consider helpful to make operational decisions and other activities that increase shareholder control and surveillance and encourage managers to internalise the frames and objectives of shareholder value creation. Symbolic categories that include hierarchical financial accountability within a narrative of “support” and “partnership” masks “financialisation” behind a rhetoric of “business orientation”.
Pro‐neurocognitive and anti‐sarcopenic benefits of one‐year metformin therapy in ovariectomized aged mice
Authors: Zakeri Maryam , Fatemi Iman , Kaeidi Ayat , Zakeri Mohammad Ali , Hakimizadeh Elham , Hassanipour Mahsa , Rahmani Mohammadreza , Hassanshahi Jalal , Ayoobi Fatemeh , Allahtavakoli Mohammad 
Published: July 2019

AbstractHealth promotion and healthy nutrition significantly increased life expectancy around the world. Aging is associated with an increase in age‐related diseases. The use of metformin (Met) as an anti‐aging drug has recently been proposed based on its widespread use in clinical practice. Reports have shown that Met acts as an anti‐aging agent. In this study, the effects of long‐term, 1 year, Met administration on aging‐related behaviors and longevity in ovariectomized mice was studied. Met (1 and 10 mg/kg, daily) was administered orally in ovariectomized mice. The anxiety‐like behavior, working memory, and physical strength were measured through elevated plus maze, Y‐maze, vertical grid holding, and the obligatory swimming capacity tests. Brains were harvested to measure brain‐derived neurotrophic factor (BDNF) level. Also, the Kaplan‐Meier survival curves were used to show differences and similarities in survival patterns. Met (10 mg/kg) decreased anxiety‐like behaviors as well as increased muscle strength and working memory in the ovariectomized mice. Moreover, Met increased the physical strength and longevity as well as the level of BDNF in the ovariectomized mice. Our results indicate that Met administration can be an effective strategy for having a healthy aging in the absence of female gonadal hormones and reverses deleterious effects of ovariectomy‐induced aging possibly through BDNF.
Development and Optimization of Cold Plasma Pretreatment for Drying on Corn Kernels
Authors: Li Shuai , Chen Shanshan , Han Feng , Xv Yan , Sun Huimin , Ma Zhongsu , Chen Junyi , Wu Wenfu 
Published: July 2019

AbstractThis study was conducted to optimize a process of cold plasma pretreatment for hot‐air drying on corn kernels. Effects of plasma pretreatment time (30, 40, 50 s), plasma pretreatment power (300, 400, 500 W) and drying temperature (37.5, 45, 52.5 °C) on drying time and drying rate during this process were investigated. Polynomial equations were established through a three‐factor and three‐level Box‐Behnken design and used to evaluate the optimal operational conditions for the drying process. The optimal pretreatment conditions were drying temperature at 52.5 °C, plasma pretreatment time of 50 s and plasma pretreatment power of 500 W, and the corresponding drying rate and drying time were 3.6163 (g/g h−1) and 1.29 hr, respectively. The AFM images showed that cold plasma pretreatment can change the topography of the treated surface with some micro‐holes, which explain how the plasma pretreatment can improve the drying process.Practical ApplicationCold plasma pretreatment can improve the efficiency of corn kernels drying. Furthermore, it has potential application for reducing energy consumption in drying. Cold plasma pretreatment could be potentially applied in grain drying.
Does hallucination perceptual modality impact psychosis risk?
Authors: Niles H. F. , Walsh B. C. , Woods S. W. , Powers A. R. 
Published: July 2019

ObjectiveSubthreshold perceptual abnormalities are commonly used to identify individuals at clinical high risk (CHR) for developing a psychotic disorder. Predictive validity for modality‐specific perceptual abnormality severity on psychosis risk is unknown.MethodsWe examined prospectively collected data from 164 individuals age 12–35 meeting criteria for CHR followed for 6–24 months or until conversion to psychosis. Using intake interview notes, baseline perceptual abnormality scores were split into auditory, visual, somatic/tactile, and olfactory/gustatory components, and auditory scores were further split into those for verbal vs non‐verbal content. Relationships between perceptual abnormality characteristics and conversion were assessed with Cox proportional hazards regression and logistic regression.ResultsUnusual thought content and paranoia were predictive of conversion, but no modality‐specific perceptual abnormality score predicted conversion status or days to conversion. However, when auditory perceptual abnormalities were further categorized as verbal vs non‐verbal, the severity of verbal experiences was predictive of conversion to psychosis (P = 0.007).ConclusionsPerceptual abnormality scores failed to meaningfully predict conversion to psychosis in either direction in this CHR sample. However, verbal auditory experiences may identify a group of CHR individuals at elevated risk of conversion. Further exploration of the relationship between phenomenological aspects of perceptual abnormalities and conversion risk is warranted.
The International Society for Plastination
Authors: Latorre Rafael , Henry Robert , Adds Philip J. , Baptista Carlos 
Published: July 2019

AbstractThe International Society for Plastination (ISP) was conceived as a means of defining plastination as an area of professional activity and serving as an agency for disseminating information relative to the art and science of plastination. In this paper, we present the purpose of ISP, the Journal of Plastination, the Plastination Index and the different international meetings organised by ISP.
The impact of the prostaglandin D2 receptor 2 and its downstream effects on the pathophysiology of asthma
Authors: Brightling Christopher E. , Brusselle Guy , Altman Pablo 
Published: July 2019

AbstractCurrent research suggests that the prostaglandin D2 (PGD2) receptor 2 (DP2) is a principal regulator in the pathophysiology of asthma, because it stimulates and amplifies the inflammatory response in this condition. The DP2 receptor can be activated by both allergic and nonallergic stimuli, leading to several pro‐inflammatory events, including eosinophil activation and migration, release of the type 2 cytokines interleukin (IL)‐4, IL‐5 and IL‐13 from T helper 2 (Th2) cells and innate lymphoid cells type 2 (ILCs), and increased airway smooth muscle mass via recruitment of mesenchymal progenitors to the airway smooth muscle bundle. Activation of the DP2 receptor pathway has potential downstream effects on asthma pathophysiology, including on airway epithelial cells, mucus hypersecretion, and airway remodelling, and consequently might impact asthma symptoms and exacerbations. Given the broad distribution of DP2 receptors on immune and structural cells involved in asthma, this receptor is being explored as a novel therapeutic target.
Intrahepatic cholestasis of pregnancy and comorbidity: A 44‐year follow‐up study
Authors: Hämäläinen Suvi‐Tuulia , Turunen Kaisa , Mattila Kari J. , Kosunen Elise , Sumanen Markku 
Published: July 2019

AbstractIntroductionIntrahepatic cholestasis of pregnancy (ICP) is a reversible liver disorder occurring during pregnancy. It has a typical genetic background with known genetic mutations and can be considered an expression of this genetic predisposition. The objective of this study was to determine whether ICP is associated with specific long‐term comorbidity.Material and methodsThe study population comprised 571 women with ICP in at least one pregnancy who were compared with 1333 pregnant women without ICP during 1969‐1988 at Tampere University Hospital, Finland. The cohort's follow‐up time was 44 years. All ICD‐10 classification discharge diagnoses were examined for the women in the ICP group from 1998 to 2013 and ICD‐10 diagnoses from outpatient care from 1969 to 2013.ResultsAt least one disease of the digestive system had been diagnosed in 50.4% (288/571) of the ICP mothers compared with 34.4% (459/1333) of the reference group (P < 0.001). In a more detailed analysis, women with a history of ICP had an increased risk for cholelithiasis and/or cholecystitis (odds ratio [OR] 2.88, 95% confidence interval [CI] 2.17 to 3.84), diseases of the pancreas (OR 2.26, 95% CI 1.20 to 4.27) and hypothyroidism (OR 2.38, 95% CI 1.27 to 4.46) compared with the reference group. Arterial diseases were less common in the ICP mothers than in the reference group (OR 0.38, 95% CI .15 to .99). Regarding other diseases, there were no statistically significant differences between the ICP mothers and reference group.ConclusionsHalf of the women with a history of ICP were diagnosed with at least one disease of the digestive system compared with a third in the reference group. The risk of cholelithiasis, cholecystitis, diseases of the pancreas and hypothyroidism was increased compared with the reference group. These are important facts when counseling women after a pregnancy with ICP. Also, this is of importance for the general practitioners and other physicians who take care of these women.
A Theory of Planned Behavior‐Based Program to Increase Physical Activity in Overweight/Obese Military Personnel: A Randomised Controlled Trial
Authors: Sanaeinasab Hormoz , Saffari Mohsen , Dashtaki Mohammad‐ali , Pakpour Amir H. , Karimi Zarchi Aliakbar , O'Garo Keisha‐Gaye N. , Koenig Harold G. 
Published: July 2019

BackgroundDesigning a health promotion program to increase physical activity may contribute to weight management. The purpose of this study was to investigate a theory of planned behavior (TPB) program to address this problem in military people.MethodsEighty‐four obese/overweight military personnel were randomised into the intervention or control group. A questionnaire assessed demographics, aspects of the TPB program, and physical activity levels. Also assessed were blood glucose and lipid levels. The intervention consisted of seven educational sessions based on TPB. Data were collected at baseline and 3 months after the intervention.ResultsAll constructs of the TPB improved between baseline and follow‐up in the intervention group (p < .001), while there were no significant changes in the control group (within‐group comparisons). Between‐group comparisons on TPB measures revealed differences in all domains when results were controlled for baseline covariates. Greater light and moderate physical activity was observed in the intervention group. Body mass index decreased significantly within the intervention group (p < .001). Changes in triglyceride and high‐density lipoprotein also favored the intervention over the control group.ConclusionAn intervention based on the TPB may be effective in promoting physical activity and decreasing weight in military personnel who are obese or overweight.
Identifying an optimal lymph node yield for penile squamous cell carcinoma: prognostic impact of surgical dissection
Authors: Chipollini Juan , Azizi Mounsif , Lo Vullo Salvatore , Mariani Luigi , Zhu Yao , Ye Ding W. , Ornellas Antonio Augusto , Watkin Nick , Ager Michael , Hakenberg Oliver , Heidenreich Axel , Raggi Daniele , Catanzaro Mario , Ornellas Paulo , Salvioni Roberto , Cheriyan Salim K. , Necchi Andrea , Spiess Phillippe E. 
Published: July 2019

ObjectiveTo evaluate the prognostic impact of lymph node yield (LNY) on survival outcomes for penile squamous cell carcinoma (SCC).Patients and methodsIn all, 532 patients who underwent inguinal LN dissection (ILND) across tertiary referral centres from Europe, China, Brazil and North America were retrospectively evaluated. From this cohort, 198 patients received pelvic LND (PLND).We identified threshold values for ILND and PLND using receiver operating characteristic curves. We tested prognostic value of LNY for recurrence‐free survival (RFS), disease‐specific survival (DSS), and overall survival (OS) using the Kaplan–Meir method and Cox proportional hazard regression models.ResultsThe median (interquartile [IQR]) age was 59 (49–68) years and the median (IQR) follow‐up after ILND was 28 (12–68.2) months. Overall, 85% of the patients had bilateral dissections. The median (IQR) number of inguinal LNs removed was 15 (10–22). Of those receiving PLND, The median (IQR) number of LNs was 13 (8–19). A LNY of ≥15 was used for dichotomisation of ILND patients, and a LNY of ≥9 was used in the PLND cohort. Patients with a LNY ≥15 had significantly better 5‐year OS vs patients with a LNY <15 (70.1% vs 58.7%). On multivariable analyses, a LNY ≥15 was a predictor of OS (hazard ratio [HR] 0.68, P = 0.029). For cN0 patients, a LNY ≥15 was an independent predictor of RFS (HR 0.52, P = 0.043) and OS (HR 0.53, P = 0.021). In the PLND cohort, a LNY ≥9 was a predictor of RFS (HR 0.53, P = 0.032).ConclusionsUsing one of the largest LND datasets to date, we found LNY to be a significant predictor of outcomes after lymphatic staging for penile SCC. Prospective validation is warranted.
Interdomain twists of human thymidine phosphorylase and its active–inactive conformations: Binding of 5‐FU and its analogues to human thymidine phosphorylase versus dihydropyrimidine dehydrogenase
Authors: Tozer Tiffany , Heale Kali , Manto Chagas Caroline , de Barros Andre Luis Branco , Alisaraie Laleh 
Published: July 2019

Abstract5‐fluorouracil (5‐FU) is an anticancer drug, which inhibits human thymidine phosphorylase (hTP) and plays a key role in maintaining the process of DNA replication and repair. It is involved in regulating pyrimidine nucleotide production, by which it inhibits the mechanism of cell proliferation and cancerous tumor growth. However, up to 80% of the administered drug is metabolized by dihydropyrimidine dehydrogenase (DPD). This work compares binding of 5‐FU and its analogues to hTP and DPD, and suggests strategies to reduce drug binding to DPD to decrease the required dose of 5‐FU. An important feature between the proteins studied here was the difference of charge distribution in their binding sites, which can be exploited for designing drugs to selectively bind to the hTP. The 5‐FU presence was thought to be required for a closed conformation. Comparison of the calculation results pertaining to unliganded and liganded protein showed that hTP could still undergo open–closed conformations in the absence of the ligand; however, the presence of a positively charged ligand better stabilizes the closed conformation and rigidifies the core region of the protein more than unliganded or neutral liganded system. The study has also shown that one of the three hinge segments linking the two major α and α/β domains of the hTP is an important contributing factor to the enzyme's open–close conformational twist during its inactivation–activation process. In addition, the angle between the α/β‐domain and the α‐domain has shown to undergo wide rotations over the course of MD simulation in the absence of a phosphate, suggesting that it contributes to the stabilization of the closed conformation of the hTP.
Quantitative clinical adjustment analysis of posterior single implant crown in a chairside digital workflow: A randomized controlled trial
Authors: Zhang Yifan , Tian Jiehua , Wei Donghao , Di Ping , Lin Ye 
Published: July 2019

AbstractObjectivesTo compare the three‐dimensional changes in quantity and morphology following clinical adjustment of a posterior single implant crown between chairside digital workflow (test) and hybrid digital workflow (control).Materials and MethodsA total of 33 participants were included for single‐tooth replacement with screw‐retained crowns in posterior sites of either the maxillary or mandible. A total of 17 participants were carried to a chairside digital workflow, receiving monolithic lithium disilicate (LS2)‐crowns (test), while the remaining 16 participants were fitted with CAD/CAM‐fabricated zirconia superstructures and hand‐layered ceramic veneering crowns (control). As each crown underwent intraoral scanning (3Shape TRIOS Color, 3Shape), 3D digital models were rendered. These scans were taken both before and after try‐in. Clinical adjustment dimensional changes were measured by superimposing the optical scans of models within a reverse software (Geomagic Control 2014). Adjustment counts and amounts (from vertical dimension) between two workflows were assessed and compared. Time consumption was recorded for efficiency analysis.ResultsAll patients were successfully treated in both groups. The median maximum vertical adjustment (taking both occlusal and interproximal surfaces into consideration) was 237 μm ± 112 in the test group and 485 μm ± 195 in the control group (p < .0001), respectively. The median adjustment count was 2.00 ± 1.09 in test group and 3.00 ± 1.05 in control group (p = .001), respectively. The total active working time/ total time for two workflows was 92.3/113.7 min for the test group and 146.3/676.3 min for the control group, respectively.ConclusionThe test group showed fewer adjustments and apparent precision on the occlusal surface compared with the control group with only a fifth of the consumption of a hybrid workflow.
The Sound of the Past: Sound in the Exhibition at the Danish Museum Mosede Fort, Denmark 1914–18
Authors: Hjortkjær Kamilla 
Published: July 2019

AbstractPart of our cultural heritage is the sound that surrounds us. Is there a particular sound for a particular historical period? How can a curator in a historical museum use sound in the exhibition for the purpose of enhancing the experience of a particular historical period, event or place? This case study includes contemporary examples from the Danish museum Mosede Fort, Denmark 1914–18. The museum have deliberately chosen to use sound and soundscapes in the permanent exhibition. Through the use of diverse sound installations, the museum have achieved working with audience immersion and discovery. With the help of sounds, the museum’s rooms and the stories from the past are experienced, rather than simply exhibited using original objects. The exhibition rooms become spaces where museum visitors experience history through all their senses, thus becoming immersed in a journey of discovery.
Physical, occupational, and speech therapy for children with cerebral palsy
Authors: McCoy Sarah Westcott , Palisano Robert , Avery Lisa , Jeffries Lynn , Laforme Fiss Alyssa , Chiarello Lisa , Hanna Steve 
Published: July 2019

AimTo explore the relationship between rehabilitation therapies and development in children with cerebral palsy (CP).MethodWe conducted a prospective, longitudinal study involving 656 children with CP (mean age [SD] 6y [2y 8mo] at study entry; 1y 6mo–11y 11mo; 287 females, 369 males), and their parents. Children were assessed two to five times over 2 years by therapists using standardized measures of balance and walking endurance. Parents completed questionnaires on demographics, rehabilitation therapies, and their children’s performance in self‐care and participation in recreation. Therapists and parents collaboratively classified children’s Gross Motor Function Classification System (GMFCS) levels. We created longitudinal graphs for each GMFCS level, depicting change across time using centiles. Using multinomial models, we analyzed the relationship between therapies (amount, focus, family‐centeredness, and the extent therapies met children’s needs) and whether change in balance, walking endurance, and participation was ‘more than’ and ‘less than’ the reference of ‘as expected’.ResultsChildren were more likely to progress ‘more than expected’ when participating in recreation when therapies were family‐centered, met children’s needs, and focused on structured play/recreation. A focus on health and well‐being was positively associated with participation and self‐care. The amount of therapy did not predict outcomes.InterpretationTherapy services that are family‐centered, consider the needs of the child, and focus on structured play/recreational activities and health/well‐being may enhance the development of children with CP.What this paper adds

Family‐centered rehabilitation therapies were positively associated with greater participation in family/recreation activities and walking endurance.

Parental perception that rehabilitation therapies met children’s needs was associated with greater participation in family/recreation activities.

Structured play, recreational activities, and health/well‐being are important for self‐care and participation when planning rehabilitation therapy.

The amount of rehabilitation therapy was not related to developmental outcomes.
Historical and philosophical perspectives on the study of developmental bias
Authors: Brigandt Ingo 
Published: July 2019

AbstractThroughout the recent history of research at the intersection of evolution and development, notions such as developmental constraint, evolutionary novelty, and evolvability have been prominent, but the term “developmental bias” has scarcely been used. And one may even doubt whether a unique and principled definition of bias is possible. I argue that the concept of developmental bias can still play a vital scientific role by means of setting an explanatory agenda that motivates investigation and guides the formulation of integrative explanatory frameworks. Less crucial is a definition that would classify patterns of phenotypic variation and unify variational patterns involving different traits and taxa as all being “bias.” Instead, what we should want is a concept that generates intellectual identity across various researchers, and that unites the diverse fields and approaches relevant to the study of developmental bias, from paleontology to behavioral biology. I point to some advantages of conducting research specifically under the label of “developmental bias,” compared with employing other, more common terms such as “evolvability.”