bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adolescents’ Perceptions of “Cheating” in Gaming and Educational Settings
Authors: Nease Brandon , Samura Michelle 
Published: March 2018

Background. Given the widespread popularity of video gameplay among adolescents, it is important to understand the relationship between video gameplay and adolescent behaviors in various contexts. Aim. This exploratory study aimed to explore adolescent gamers use of player guides and cheat codes during video gameplay in order to understand how they reason about the relationship between cheating in video games and cheating in academic settings. Method. Semi-structured interviews were conducted with adolescents in order to gain in-depth insight into participants’ perspectives on video gameplay and their perceptions of cheating in video games and academic settings. Interview data was coded and qualitatively analyzed to identify patterns and key emergent themes. Results. Findings from this exploratory study highlight seemingly contradictory views on cheating among adolescents. On the one hand, participants viewed player guides, cheat codes, and other forms of gameplay resources as simply part of the overall gaming experience. They did not view this type of assistance as cheating. On the other hand, participants viewed unsanctioned assistance and taking others’ ideas as their own as cheating within academic settings. Conclusion. As findings from this study suggest, understanding how student navigate video gameplay may provide much needed insight into providing effective supports and tools in academic contexts. Findings from this research can inform the development of more effective approaches to address cheating in academic settings, including the integration of study guides, student-created aids and guides and additional materials as part of an effective support system.
A case series of favorable vessel dilatation using a nitinol scoring element–equipped helical balloon catheter (AngioSculpt®)
Authors: Sato Ryo , Sato Tetsuhiko , Shirasawa Yuichi , Kondo Chika , Tadakoshi Masao , Fukuda Michio , Ohte Nobuyuki , Morozumi Kunio 
Published: March 2018

Objective: Although percutaneous transluminal angioplasty is an effective therapy against vascular access failure in hemodialysis patients, recurrent stenosis imposes enormous burden for hemodialysis patients. A nitinol scoring element–equipped helical balloon catheter (AngioSculpt®) has been altered the landscape for treating several vascular diseases. It is not, however, fully elucidated whether AngioSculpt for advanced vascular access stenosis, difficult to expand by conventional balloons, successfully provides bailout angioplasty. Here, we report our cases whose intradialytic venous pressure significantly improved after percutaneous transluminal angioplasty without any serious adverse complications using AngioSculpt. Patients and Methods: Among patients undergoing hemodialysis in Masuko Memorial Hospital, 16 cases with resistant and recurrent vascular access stenosis underwent AngioSculpt (diameter 6 mm, total length 4 cm) angioplasty. We simultaneously measured the average venous pressures during hemodialysis before and after percutaneous transluminal angioplasty. Results: The average outflow vessel stenosis rate was 73.0 ± 11.3% before AngioSculpt intervention. Fully enlarged vessels were observed by expanding vessels at maximum pressure of 14 atm in all cases without any complications including vascular ruptures. Their intradialytic venous pressures decreased from 181.8 ± 39.2 mmHg to 150.5 ± 39.3 mmHg ( p < 0.0001). Conclusion: AngioSculpt may provide a promising option for treating hemodialysis patients with severely advanced vascular access stenosis, who would otherwise need repeated vascular access surgeries and/or conventional percutaneous transluminal angioplasties.
Significance of Intraoperative Revision During Arterial Switch Operation in the Current Era
Authors: Nakamura Yuki , Kalfa David , Chai Paul , Chelliah Anjali , Freud Lindsay , Bacha Emile , Quaegebeur Jan 
Published: March 2018

Background: Arterial switch operation (ASO) is a relatively safe operation nowadays. We hypothesize that intraoperative revision for coronary malperfusion still plays an important role during ASO in the current era. Methods: From January 2005 to May 2016, 244 patients underwent ASO. Medical records were reviewed and the details of intraoperative revision were described. Morbidity and mortality were compared in patients with/without intraoperative revision. Factors related to the need for intraoperative revision were analyzed. Results: Seventeen (7%) patients needed intraoperative revision. As a technique for intraoperative revision, revision of a coronary button was performed in eight patients and revision of the main pulmonary artery anastomosis to relieve compression on the coronary artery was performed in five patients. Factors related to intraoperative revision were body weight at surgery ( P = .051), eccentric position of the coronary ostium ( P = .01), single coronary artery system ( P = .03), and intramural coronary artery ( P = .003). The commonest coronary artery origin and branching pattern was not protective against the need for intraoperative revision ( P = .43). Discharge mortality was 2% overall: 2 of 17 with intraoperative revision versus 3 of 238 without it ( P = .04). Patients who underwent intraoperative revision had longer postoperative hospitalization ( P = .003). Conclusion: The need for intraoperative revision was related to eccentric coronary ostium, single coronary artery, and intramural coronary artery. Although the need for intraoperative revision correlated with higher mortality and morbidity, prompt intraoperative revision also likely contributed to our good results after ASO.
Head formation requires Dishevelled degradation that is mediated by March2 in concert with Dapper1
Authors: Lee Hyeyoon , Cheong Seong-Moon , Han Wonhee , Koo Youngmu , Jo Saet-Byeol , Cho Gun-Sik , Yang Jae-Seong , Kim Sanguk , Han Jin-Kwan 
Published: March 2018

ABSTRACT
Dishevelled (Dvl/Dsh) is a key scaffold protein that propagates Wnt signaling essential for embryogenesis and homeostasis. However, whether the antagonism of Wnt signaling that is necessary for vertebrate head formation can be achieved through regulation of Dsh protein stability is unclear. Here, we show that membrane-associated RING-CH2 (March2), a RING-type E3 ubiquitin ligase, antagonizes Wnt signaling by regulating the turnover of Dsh protein via ubiquitin-mediated lysosomal degradation in the prospective head region of Xenopus. We further found that March2 acquires regional and functional specificities for head formation from the Dsh-interacting protein Dapper1 (Dpr1). Dpr1 stabilizes the interaction between March2 and Dsh in order to mediate ubiquitylation and the subsequent degradation of Dsh protein only in the dorso-animal region of Xenopus embryo. These results suggest that March2 restricts cytosolic pools of Dsh protein and reduces the need for Wnt signaling in precise vertebrate head development.
O gótico no livro Literatura Brasileira: em diálogo com outras literaturas e outras linguagens
Authors: Oliveira Márcio Alessandro de 
Published: March 2018

Assumindo uma hipótese segundo a qual os manuais escolares podem estar em dia com o conhecimento científico tanto quanto os textos de divulgação científica, este trabalho estuda a presença do gótico no livro Literatura Brasileira: em diálogo com outras literaturas e outras linguagens. A intenção é saber como o gótico, entendido como estética e gênero, comparece no discurso didático e de que modo (implícito ou explícito) aparece tal estética. O discurso didático de William Cereja e Thereza Cochar Magalhães pode variar em novas edições, conforme a Ecdótica, sem deixar de ser condicionado pela ideologia, como postula a Análise do Discurso, ramo em que William Cereja fez doutorado. Assim, delimita-se o gótico, para saber se foi “resgatado”. O resultado da investigação é apresentado após a enumeração de passagens do texto de apresentação e dos dizeres que giram em torno de alguns literatos escolhidos pelo manual, como Álvares de Azevedo e Augusto dos Anjos. Em última análise, o objetivo deste artigo é investigar o tratamento dispensado à estética gótica, a cuja prosa o compêndio dedica um capítulo inteiro.
Ultrasensitive Detection of Chimerism by Single-Molecule Molecular Inversion Probe Capture and High-Throughput Sequencing of Copy Number Deletion Polymorphisms
Authors: Wu David , Waalkes Adam , Penewit Kelsi , Salipante Stephen J 
Published: March 2018

Abstract

BACKGROUND
Genomic chimerism, the co-occurrence of cells from different genetic origins, provides important diagnostic information in diverse clinical contexts, including graft injury detection and longitudinal surveillance of hematopoietic stem cell transplantation patients, but existing assays are limiting. Here we applied single-molecule molecular inversion probes (smMIPs), a high-throughput sequencing technology combining multiplexed target capture with read quantification mediated by unique molecular identifiers, to detect chimerism based on the presence or absence of polymorphic genomic loci.

METHODS
We designed a 159-smMIP panel targeting 40 autosomal regions of frequent homozygous deletion across human populations and 2 sex-linked loci. We developed methods for detecting and quantitating loci absent from 1 cell population but present in another, which could be used to sensitively identify chimeric cell populations.

RESULTS
Unrelated individuals and first-degree relatives were highly polymorphic across the loci examined. Using synthetic DNA mixtures, limits of detection of at least 1 in 10000 chimeric cells were demonstrated without prior knowledge of genotypes, and mixtures of up to 4 separate donors could be deconvoluted. Quantitative linearity over 4 orders of magnitude and false-positive rates &lt;1 in 85000 events were achieved. Eleven of 11 posttransplant clinical specimens from patients with hematological malignancies testing positive for residual cancer by conventional methods had detectable chimeric populations by smMIP, whereas 11 of 11 specimens testing negative by conventional methods were low-positive for chimerism by smMIP.

CONCLUSIONS
smMIPs are scalable to high sensitivity and large numbers of informative markers, enabling ultrasensitive chimerism detection for many clinical purposes.
Excitatory Neuronal Responses of Ca2+Transients in Interstitial Cells of Cajal in the Small Intestine
Authors: Baker Salah A. , Drumm Bernard T. , Skowronek Karolina E. , Rembetski Benjamin E. , Peri Lauren E. , Hennig Grant W. , Perrino Brian A. , Sanders Kenton M. 
Published: March 2018

AbstractInterstitial cells of Cajal (ICC) regulate smooth muscle excitability and motility in the gastrointestinal (GI) tract. ICC in the deep muscular plexus (ICC-DMP) of the small intestine are aligned closely with varicosities of enteric motor neurons and thought to transduce neural responses. ICC-DMP generate Ca2+transients that activate Ca2+activated Cl-channels and generate electrophysiological responses. We tested the hypothesis that excitatory neurotransmitters regulate Ca2+transients in ICC-DMP as a means of regulating intestinal muscles. High-resolution confocal microscopy was used to image Ca2+transients in ICC-DMP within murine small intestinal muscles with cell-specific expression of GCaMP3. Intrinsic nerves were stimulated by electrical field stimulation (EFS). ICC-DMP exhibited ongoing Ca2+transients before stimuli were applied. EFS caused initial suppression of Ca2+transients, followed by escape during sustained stimulation, and large increases in Ca2+transients after cessation of stimulation. Basal Ca2+activity and the excitatory phases of Ca2+responses to EFS were inhibited by atropine and neurokinin 1 receptor (NK1) antagonists, but not by NK2 receptor antagonists. Exogenous ACh and substance P (SP) increased Ca2+transients, atropine and NK1 antagonists decreased Ca2+transients. Neurokinins appear to be released spontaneously (tonic excitation) in small intestinal muscles and are the dominant excitatory neurotransmitters. Subcellular regulation of Ca2+release events in ICC-DMP may be a means by which excitatory neurotransmission organizes intestinal motility patterns.
Dopaminergic Drug Effects on Probability Weighting during Risky Decision Making
Authors: Ojala Karita E. , Janssen Lieneke K. , Hashemi Mahur M. , Timmer Monique H. M. , Geurts Dirk E. M. , ter Huurne Niels P. , Cools Roshan , Sescousse Guillaume 
Published: March 2018

AbstractDopamine has been associated with risky decision-making, as well as with pathological gambling, a behavioral addiction characterized by excessive risk-taking behavior. However, the specific mechanisms through which dopamine might act to foster risk-taking and pathological gambling remain elusive. Here we test the hypothesis that this might be achieved, in part, via modulation of subjective probability weighting during decision making. Human healthy controls (n= 21) and pathological gamblers (n= 16) played a decision-making task involving choices between sure monetary options and risky gambles both in the gain and loss domains. Each participant played the task twice, either under placebo or the dopamine D2/D3receptor antagonist sulpiride, in a double-blind counterbalanced design. A prospect theory modelling approach was used to estimate subjective probability weighting and sensitivity to monetary outcomes. Consistent with prospect theory, we found that participants presented a distortion in the subjective weighting of probabilities, i.e., they overweighted low probabilities and underweighted moderate to high probabilities, both in the gain and loss domains. Compared with placebo, sulpiride attenuated this distortion in the gain domain. Across drugs, the groups did not differ in their probability weighting, although gamblers consistently underweighted losing probabilities in the placebo condition. Overall, our results reveal that dopamine D2/D3receptor antagonism modulates the subjective weighting of probabilities in the gain domain, in the direction of more objective, economically rational decision making.
Analisis Penerima Raskin (Beras untuk Rumah Tangga Miskin) di Provinsi Jawa Tengah
Authors: Khomsatun Siti 
Published: March 2018

Pelaksanaan program raskin di lapangan menunjukkan bahwa pendistribusian raskin masih belum sesuai ketentuan. Menurut data BPS disebutkan bahwa pada tahun 2014 rata-rata jumlah raskin yang diterima oleh 20 persen rumah tangga dengan pengeluaran terendah di Jawa Tengah adalah sebanyak 5,60 kg padahal mereka seharusnya menerima 15 kg per bulan dan rata-rata harga yang dibayar untuk membeli raskin sebesar Rp. 2.070 per kg padahal mereka seharusnya membayar dengan harga Rp. 1.600 per kg. Sumber data yang digunakan dalam penelitian ini adalah data sekunder yang berasal dari data Susenas 2015 pada BPS Provinsi Jawa Tengah yang berisi data tentang sosial dan ekonomi rumah tangga. Teknis analisis yang digunakan adalah analisis tabulasi silang (crosstab).Hasil dari penelitian ini adalah masih ada rumah tangga yang menurut kategori kemiskinan seharusnya menerima raskin namun tidak menerima raskin dan sebaliknya terdapat rumah tangga yang tidak miskin dan seharusnya tidak menerima raskin namun menerima raskin. Rumah tangga penerima raskin yang masuk kategori sangat miskin, miskin, hampir miskin, dan rentan miskin lainnya dan menerima raskin sebanyak 15 kg hanya sebagian kecil, padahal seharusnya rumah tangga sasaran program raskin menerima raskin sebanyak 15 kg per bulan sesuai pedoman raskin. Penelitian ini memiliki tujuan menganalisis karakteristik penerima raskin di Provinsi Jawa Tengah.
Raskin program implementation in the field shows that the distribution of raskin still not according to regulations. The agency noted that in 2014 the average number of raskin received by 20 percent of households with the lowest expenditure in Central Java is as much as 5.60 kg when they are supposed to receive 15 kg per month and the average price paid to purchase raskin Rp. 2,070 per kg when they should be paying the price of Rp. 1,600 per kg. The data used in this research is secondary data derived from the data Susenas 2015 at Statistics of Central Java Province which contains data on the social and economic households. Technical analysis is the analysis of cross tabulation (crosstab). The results of this study are still households by poverty category should receive raskin but did not receive raskin and instead there are households that are not poor and should not receive raskin but received raskin. Raskin recipient households were categorized as very poor, poor, near poor, and vulnerable other poor receive raskin as much as 15 kg only a small part, when it should raskin program target households receive raskin as much as 15 kg per month as per the guidelines raskin. This study has purpose of analysis the characteristics of raskin recipient in Centran Java
Analisis Rantai Nilai Komoditas Cabai Merah di Agrowisata Desa Candi Kecamatan Bandungan Kabupaten Semarang
Authors: Oridilla B Dhamon 
Published: March 2018

Tujuan penelitian ini adalah untuk untuk mengidentifikasi pola distribusi cabai merah, untuk mengetahui setiap nilai rantai komoditas dan distribusi, untuk mendesain pola distribusi alternatif cabai merah. Populasi dalam penelitian ini adalah 88 responden dari 735 jumlah anggota petani cabai di Desa Candi dengan luas lahan sebesar 150,3 hektar yang terdiri dari sawah, tegalan dan pekarangan. Metode analis data mengunakan pendekatan kuantitatif dilakukan dengan menggunakan Analisis Margin Pemasaran.Hasil penelitian meliputi : (1) Pola distribusi usaha tani yang ada tumbuh secara alami sesuai dengan perkembangan dan kebutuhan pelakunya, pelaku yang ada dalam pola ini adalah petani, tengkulak, penggumpul, pedagang besar, pengecer, konsumen. (2) Nilai rantai komoditas cabai merah dalam pola yang tumbuh secara alami ini, seringkali menjadikan penetapan harga lebih dominan oleh pedagang, sehingga petani menerima harga sedikit lebih rendah dibandingkan harga pasar. (3) Beberapa kendala yang dihadapi dalam pendistribusian cabai merah adalah sulitnya merubah pola pikir masyarakat tentang usaha tani yang maju, hal ini dimanfaakan baik oleh para pelaku pasar (mata rantai distribusi) yang lebih menguasai informasi dan selalu mengikuti perkembangan dinamika pasar.
The purpose of this research is to identify the distribution pattern of red pepper, to know each value of commodity chains and distribution, to design alternative distribution pattern of red pepper.Population in this research is 88 respondents from 735 of member of chilli farmer in Desa Candi with total area of 150,3 hectare consisting of rice field, moor and yard. Methods of data analyst using quantitative approach is done by using Margin Marketing Analysis.The results include: (1) The pattern of distribution of existing farming business grows naturally in accordance with the developments and needs of the perpetrators, the actors in this pattern are farmers, wholesalers, collectors, wholesalers, retailers, consumers. (2) The value of the red chili commodity chain in this naturally grown pattern often makes pricing more dominant by traders, so farmers receive prices slightly lower than market prices. (3) Some obstacles faced in distributing red peppers are the difficulty of changing the mindset of the community about advanced farming, this is best utilized by market participants (chain of distribution) who are more informed and always keep abreast of market dynamics.
Sensory Elements and Devices Operational Diagnostic Blood Glucose
Authors: Kogut I.T. , Kotyk M.V. 
Published: March 2018

The problem of monitoring diabetes is caused as a significant prevalence of the disease, and development on this basis of complex related complications, early disability and mortality. [1] So important is operational and continuous monitoring of blood glucose (MBG), which will increase rates treatment of diabetes.
Currently developed compact diagnostic system CMG for both the clinic and personal use. These systems are the most invasive, requiring immediate blood sampling. At the same time, become of diagnostic devices which are based on non-invasive method that the accuracy inferior invasive, but is more promising, because they have more functionality in terms of ease of measurement, storage and processing results. These systems include a measuring device and sensor elements. This paper will review methods and analysis of the basic principles of measurement devices MBG to develop circuit solutions for the creation of sensor and microsystem elements for noninvasive monitoring MBG.
Peculiarities of Chemisorption of Dimethyl Carbonate on Silica Surface
Authors: Protsak I.S. , Pakhlov E.M. , Tertykh V.A. 
Published: March 2018

This paper presents the results of studies of dimethyl carbonate interaction with sites of the fumed silica surface. The investigations were performed in a vacuum quartz cuvette using IR spectroscopy method. Chemical interaction of dimethyl carbonate with sites of the dehydrated silica surface was shown to occur at temperature of 200 °C and higher, chemisorption processes take place involving both structural silanol groups and siloxane bridges on the surface.
Effect of Carbon on the Physical and Structural Properties of Boride Fe2B
Authors: Filonenko N.Yu. , Galdina O.M. 
Published: March 2018

For Fe-В and Fe-В-С system alloys one of the structure constituent is iron boride Fe2B but in the literature there is no information on carbon solubility limit in iron boride Fe2В. The object of this paper is to reveal the effect of carbon on the physical and structural properties of boride Fe2В.
Investigation was performed for the specimens with carbon content of 0,05 - 0,80 % (wt.) and boron content of 9,0 - 15,0 % (wt.), the rest is iron. To determine the physical properties of alloys we use microstructure analysis, X-ray microanalysis and X-ray structural analysis.
It is found that carbon doping of boride Fe2В leads to a feeble lattice strain and effects on the physical characteristics of boride. We estimate the free energy of boride Fe2B and carbon content in Fe2B phase. Carbon can substitute up to 3 – 8 % of boron atoms in Fe2B phase depending on the temperature which is verified by experimental data. The carbon solubility in this phase is also examined.
Magnetic Hyperfine Structure of Epitaxial Films of Nickel Ferrite
Authors: Yushchuk S.I. , Moklyak V.V. , Yuryev S.O. 
Published: March 2018

Comparative NGR study of the parameters of the magnetic hyperfine structure of epitaxial films grown on single-crystal substrates of orientations of (100) and (111) by liquid phase epitaxy (LPE) and chemical transport reactions (CTR) is conducted. It is established that in the films obtained by the method of CTR, there is a significant number of ions of bivalent iron, which is in phase magnetite . After heat treatment of these films in air at T = 1273 K, the magnetite becomes the oxide. In the films of , grown by the LPE method the divalent iron was not detected.
As shown by calculations, the vector direction of the magnetization of films obtained by the method of LPE, lies in the film plane regardless of the orientation (100) or (111) substrates. In films obtained by the CTR method, it forms with the substrate 41 - 450.