bluuebunny/crossref_metadata_2025_split huggingface dataset:
CsPbIBr2 Thick Film With (100)‐Preferred Orientation Enables Highly Sensitive X‐Ray Detector by a Spray‐Coating Method via Dual‐Additive‐Assisted Solution Strategy under Atmospheric Environment
Authors: Lu Yingshen , He Danmin , Yuan Xiang , Yan Quanhe , Shu Xin , Hu Ziting , Zhang Zifa , Liu Zhuoyan , Jiang Zuimin , Xu Run , Wang Wenzhen , Ma Zhongquan , Chen Teng , Xu Haitao , Xu Fei , Hong Feng , Song Hongwei 
Published: November 2024

AbstractThe realization of large‐area high‐quality perovskite thick films under an atmospheric environment without humidity control is confronting an urgent challenge for the applications in X‐ray detection and imaging. A spray‐coating method with air as the gas carrier is employed to achieve large‐area perovskite thick films for X‐ray flat‐panel detection applications. To further improve the quality of the thick films, the 10 µm‐thick CsPbIBr2 films with (100)‐preferred orientation, low trap density (7.1 × 1012 cm−3) and high resistivity corresponding to low dark current (3.2 × 10−9 A) are prepared via dual‐additive‐assisted (NH4SCN and L‐α‐phosphatidylcholine (LP)) solution strategy under atmospheric environment with relative humidity of 60% (60% RH). Thus, the metal‐semiconductor‐metal‐structured (Au/CsPbIBr2/Au) transverse X‐ray detection device under 40 KeV X‐ray irradiation possesses a high sensitivity up to 1420 µC Gyair−1 cm−2 under a weak electric field of 18 V mm−1 and a low dose rate of 3.3 µGyair s−1 that is lower than a dose rate of ≈5.5 µGyair s−1 required for routine medical diagnosis. Strikingly, the unencapsulated device maintains 80% (1120 µC Gyair−1 cm−2) of the original sensitivity after 1000 h under the atmospheric environment with 45–55% RH. These results pave the way for the practical applications of perovskite thick films in X‐ray medical detection and imaging.
Atomic‐Scale Order and Disorder Induced Diverse Topological Spin Textures in Self‐Intercalated Van der Waals Magnets Cr1+δTe2
Authors: Liu Ying , Liu Yangrui , Dan Jiadong , Liu Wei , Wang Luyang , Hu Kejun , Wang Weiwei , Zhang Lei , Ge Binghui , Du Haifeng , Song Dongsheng 
Published: November 2024

AbstractThe intercalation of magnetic atoms into van der Waals (vdW) gaps offers a versatile approach for manipulating local magnetic ordering in vdW magnets. However, these intercalated magnetic atoms are often intricately positioned within the gaps, resulting in an ambiguous impact on local magnetic interactions and spin configurations. Herein, the atomic and magnetic structures of self‐intercalated prototype materials Cr1+δTe2 are comprehensively investigated using transmission electron microscopy, elucidating the correlation between the concentration and distribution of intercalated Cr atoms and the evolution of spin textures. The observed transitions from topological Néel‐type skyrmions to non‐topological type‐II bubbles, and ultimately to trivial ferromagnetic domains, underscore the complex nature of these magnetic spin textures. The complexity of the local structural arrangements is further revealed through integrating atomic‐resolution imaging, revealing the disorder‐order‐disorder transitions manifested by the distribution of intercalated atoms. The modulation of intercalated atomic structure shapes the observed spin textures by affecting the Dzyaloshinskii−Moriya interaction (DMI), inter/intra‐layer coupling, and magnetic anisotropy. These findings provide profound insights into the structure‐magnetism relationship, offering promising avenues for engineering the magnetic properties of vdW magnets at the atomic level.
Magnesium Fluoride Interlayers Enabled by Wet‐Chemical Process for High‐Performance Solid‐State Batteries
Authors: Jia Meiqi , Wu Ting‐Ting , Zhang Si‐Dong , Guo Sijie , Fu Yongzhu , Cao An‐Min 
Published: November 2024

AbstractGarnet‐type solid‐state electrolytes (SSEs) exemplified by Li6.5La3Zr1.5Ta0.5O12 (LLZT) are chemically unstable when exposed to air, leading to the formation of impurities and poor wettability with Li metal. Herein, a protocol to address this Li/LLZT interface challenge is demonstrated by constructing a lithiophilic MgF2 nanofilm on the LLZT pellet. Specifically, a solution‐based process is developed for the surface engineering of LLZT, utilizing magnesium trifluoroacetate (MTF) as the molecular precursor while poly(acrylic acid) (PAA) as the coordinating agent in a sol‐gel process. It is demonstrated that a facile spin‐coating treatment followed by high‐temperature annealing reliably forms crack‐free MgF2 nanofilms with precise thickness control. Introduction an MgF2 interlayer transforms the LLZT pellet into a highly lithophilic, facilitating close contact with the lithium anode, thereby leading to a significantly reduced interfacial resistance from 1190 Ω cm2 to 6 Ω cm2. Such an interfacial engineering enables stable cycling of full batteries with high reversibility and rate capability using commercial LiFePO4 and LiNi0.83Co0.07Mn0.1O2 as cathodes. This study unfolds the possibility of a solution‐based method as a facile and scalable process for the construction of fluoride nanofilms, which is promising to address the critical interfacial challenges of solid‐state batteries (SSBs) to facilitate its practical applications.
Electro‐Chemo‐Mechanical Domain to Enable Less Hysteretic Fast‐Charging
Authors: Min Woosik , Hong Tae Hwa , Hwang Juncheol , Lee Yoon Hak , Kee Joonyoung , Kim Dong Jun , Lee Jung Tae , Kim Duho 
Published: November 2024

AbstractA new avenue by transforming the conventional electrochemical domain into an electro‐chemo‐mechanical domain is proposed to achieve less hysteretic fast‐charging based on the three pictures: i) electro‐chemo‐mechanics, ii) phase transition kinetics, and iii) ionic kinetics. Each concept is demonstrated leading to the electrochemical improvement using data‐driven computation and experimental analyses, and its novel framework is generalized based on alkali‐ion chalcogenide models. The mechanical strain lowers and delays the electrochemical yield point, which gives rise to extending the elastic region and enhancing the phase and ionic kinetics. This is experimentally verified with less hysteresis upon (dis)charging for all models. Implementing the electro‐chemo‐mechanical domain is central in alkali‐ion chalcogenide batteries and broadens its application in other rechargeable batteries, ultimately playing a critical role in providing practical fast‐charging solutions.
Microwave‐Assisted Fabrication of Highly Crystalline, Robust COF Membrane for Organic Solvent Nanofiltration
Authors: Xu Kai , Zheng Yu , Zhou Junjie , Zhao Yang , Pang Xiao , Cheng Lijuan , Wang Hui , Zhang Xianjuan , Zhang Runnan , Jiang Zhongyi 
Published: November 2024

AbstractFabrication of crystalline, robust covalent organic framework (COF) membranes based on disorder‐to‐order strategy is promising yet highly challenging. Herein, a microwave‐assisted method for fabricating COF membranes is proposed. Initially, monomers polymerize rapidly on the surface of porous Al2O3 substrate at room temperature to form an amorphous pristine membrane. Subsequently, a microwave field is exerted to trigger fast crystallization, acquiring a crystalline COF membrane within 60 min. The amorphous pristine membrane exhibits a high dissipation factor, indicating excellent microwave absorption capability, which accelerates the dynamic reversible reactions during the microwave treatment and thus ensures a rapid transition from the amorphous to the crystalline state. Owing to the high‐crystallinity and robust structure, the COF membranes exhibit high rejection rates for solute molecules with molecular weights exceeding 700 Da (e.g., Evans blue: 98.7%) and high solvent permeance for organic solvents (e.g., ethanol: 87.8 Lm−2h−1 bar−1, n‐hexane: 222.3 Lm−2h−1 bar−1). Surprisingly, the COF membranes exhibit superior mechanical properties, with Young's modulus of 33.91 ± 3.94 GPa, outperforming previously reported polycrystalline COF membranes and are close to those for inorganic zeolite membranes. The microwave‐assisted COF crystallization method opens a new avenue to fabricating a variety of crystalline membranes for advanced separations.
Giant Bulk Photovoltaic Power Generation in 2D AgBiP2Se6 Crystals
Authors: Li Dong , Qin Jing‐Kai , Zhu Bing‐Xuan , Yue Lin‐Qing , Qiang Sheng , Zhu Cheng‐Yi , Huang Pei‐Yu , Zhen Liang , Xu Cheng‐Yan 
Published: November 2024

AbstractWith the theoretical high power conversion efficiency (PCE) exceeding the thermodynamic Schockley–Queisser (S–Q) limit, the bulk photovoltaic (BPV) effect, which is manifested in acentric crystals across the entire visual spectrum, holds great potential for next‐generation light‐harvesting devices. Here the abnormally giant second harmonic generation (SHG) activity and BPV response in 2D AgBiP2Se6 crystals with broken inversion symmetry is demonstrated, which can be remarkably enhanced with the thickness downscaling. Based on the vertical device sandwiched with graphene electrodes, the wideband light absorption of 2D AgBiP2Se6 crystals with Eg of 1.49 eV enables giant BPV response in the entire visible spectrum, and efficient utilization of solar energy contributes to large short‐current (≈330 mA cm−2), high PCE (≈0.13%) and EQE (≈12.5%) under 532 nm light illumination. Furthermore, benefitting from the local ion redistribution driven by an in‐plane electric field, the BPV photocurrent generation is effectively enhanced 3 times, yielding an extremely high PCE of 0.18%, according high among the reported 2D acentric crystals. The study reintroduces AgBiP2Se6 to the 2D acentric crystal family and lays the groundwork to develop BPV devices for light‐harvesting applications.
Nano Plasma Membrane Vesicle‐Lipid Nanoparticle Hybrids for Enhanced Gene Delivery and Expression
Authors: Alter Claudio Luca , Lotter Claudia , Puligilla Ramya Deepthi , Bolten Jan Stephan , Sedzicki Jaroslaw , Marchese Jason , Schittny Valentin , Rucci Francesca , Beverly Michael , Palivan Cornelia G. , Detampel Pascal , Einfalt Tomaž , Huwyler Jörg 
Published: November 2024

AbstractLipid nanoparticles (LNPs) have emerged as the leading nonviral nucleic acid (NA) delivery system, gaining widespread attention for their use in COVID‐19 vaccines. They are recognized for their efficient NA encapsulation, modifiability, and scalable production. However, LNPs face efficacy and potency limitations due to suboptimal intracellular processing, with endosomal escape efficiencies (ESE) below 2.5%. Additionally, up to 70% of NPs undergo recycling and exocytosis after cellular uptake. In contrast, cell‐derived vesicles offer biocompatibility and high‐delivery efficacy but are challenging to load with exogenous NAs and to manufacture at large‐scale. To leverage the strengths of both systems, a hybrid system is designed by combining cell‐derived vesicles, such as nano plasma membrane vesicles (nPMVs), with LNPs through microfluidic mixing and subsequent dialysis. These hybrids demonstrate up to tenfold increase in ESE and an 18‐fold rise in reporter gene expression in vitro and in vivo in zebrafish larvae (ZFL) and mice, compared to traditional LNPs. These improvements are linked to their unique physico‐chemical properties, composition, and morphology. By incorporating cell‐derived vesicles, this strategy streamlines the development process, significantly enhancing the efficacy and potency of gene delivery systems without the need for extensive screening.
A General Approach for Metal Nanoparticle Encapsulation Within Porous Oxides
Authors: Zhou Chengshuang , Oh Jinwon , Stone Michael L. , Richardson Sydney , Chung Pin‐Hung , Osio‐Norgaard Jorge , Nhan Bang T. , Kumar Abinash , Chi Miaofang , Cargnello Matteo 
Published: November 2024

AbstractEncapsulation of metal nanoparticles within oxide materials has been shown as an effective strategy to improve activity, selectivity, and stability in several catalytic applications. Several approaches have been proposed to encapsulate nanoparticles, such as forming core‐shell structures, growing ordered structures (zeolites or metal‐organic frameworks) on nanoparticles, or directly depositing support materials on nanoparticles. Here, a general nanocasting method is demonstrated that can produce diverse encapsulated metal@oxide structures with different compositions (Pt, Pd, Rh) and multiple types of oxides (Al2O3, Al2O3‐CeO2, ZrO2, ZnZrOx, In2O3, Mn2O3, TiO2) while controlling the size and dispersion of nanoparticles and the porous structure of the oxide. Metal@polymer structures are first prepared, and then the oxide precursor is infiltrated into such structures and the resulting material is calcined to form the metal@oxide structures. Most Pt@oxides catalysts show similar catalytic activity, demonstrating the availability of surface Pt sites in the encapsulated structures. However, the Pt@Mn2O3 sample showed much higher CO oxidation activity, while also being stable under aging conditions. This work demonstrated a robust nanocasting method to synthesize metal@oxide structures, which can be utilized in catalysis to finely tune metal‐oxide interfaces.
2D‐SnS‐Embedded Schottky Device with Neurotransmitter‐Like Functionality Produced Using Proximity Vapor Transfer Method for Photonic Neurocomputing
Authors: Kumar Naveen , Patel Malkeshkumar , Nguyen Thanh Tai , Lee Junghyun , Choi Chanhyuk , Bhatnagar Priyanka , Kim Joondong 
Published: November 2024

AbstractNeuromorphic computing, which involves the creation of artificial synapses capable of mimicking biological brain activity, has intrigued researchers in the field of artificial intelligence (AI). To advance neuromorphic computing, a highly efficient 2D material‐based artificial synapse capable of performing logical and arithmetic operations must be developed. However, fabricating large, uniform films or high‐quality structures of 2D materials remains challenging because of their multistep and complex fabrication processes. In the present study, to produce large (Ø ≈ 3 in.), uniform, transparent neuromorphic devices, a novel single‐step approach called proximity vapor transfer (PVT) that utilizes van der Waals (vdW) materials is employed. This single‐step technique, which involves the fabrication of vdW materials on various substrates (glass, ITO, AZO, Mo, and Cu), allows control of the thickness and bandgap tunability. The Schottky device developed via the PVT method using vdW SnS with neurotransmitter (acetylcholine)‐like functionality emulates biological synapses and exhibits photoelectronic synaptic behavior with wide‐field‐of‐view synaptic plasticity. In addition, logic gate operations (NOT, OR, AND), reward‐cascade neurotransmission, and imaging can be performed using 3 × 3 arrays of the device. This study represents a significant step toward the development of transparent and large‐area synaptic devices, which are crucial for advancing AI applications.
Spatiotemporal Proximity‐Enhanced Biocatalytic Cascades Within Metal–Organic Frameworks for Wearable and Theranostic Applications
Authors: Hao Liangwen , Wang Hui , Liu Chang , Wu Zhuoyao , Yi Jinyan , Bian Kexin , Zhang Yu , Liu Dinghua , Yang Weitao , Zhang Bingbo 
Published: November 2024

AbstractEnzymatic catalysis, particularly multi‐enzyme cascade catalytic, is often limited by the spatial and temporal separation of enzymes and their signal substrates. Herein, a facile method for producing a spatiotemporal proximity‐enhanced biocatalytic cascade system is introduced by encasing enzymes within metal–organic frameworks (MOFs) that are modulated with sulfonic acid‐functionalized signal substrates. The modulated behavior relies on the sulfonic acid groups coordinated with Zn2+. As a proof of concept, by utilizing 2,2′‐Azinobis (3‐ethylbenzothiazoline‐6‐sulfonic acid ammonium salt) (ABTS), a widely‐used signal substrate for horseradish peroxidase, two‐enzyme/substrate, and three‐enzyme/substrate MOFs, which demonstrated a 7.4‐ and 10.2‐fold increase in biocatalytic efficiency over free systems are successfully synthesized. Incorporating the synthesized MOFs into homemade wearable patches and in vivo settings, noninvasive sweat glucose colorimetric detection and photoacoustic imaging‐guided photothermal tumor therapy are enabled, respectively. This advancement stems from the newly established coordinative bonds between Zn2+ centers and substrates' sulfonic acid groups, which negates the need for additional signal substrates, thereby not only enhancing but also streamlining bioapplication processes.
Gold(I)‐Catalyzed Regioselective Cycloisomerization of Bis(Indol‐3‐Yl)‐Ynamides to Access Five‐Membered Ring Linked Bisindole Derivatives
Authors: Xiao Zhanshuai , Wei Yin , Shi Min 
Published: November 2024

AbstractA gold(I)‐catalyzed regioselective cycloisomerization of bis(indol‐3‐yl)‐ynamides for the rapid construction of five‐membered ring linked bisindole derivatives has been reported, affording the desired products in the range of 72%–94% yields under mild conditions along with broad substrate scope. Moreover, DFT calculation of the NBO (natural bond orbital) charge supports the origin of its regioselectivity.
AIP1 Regulates Ocular Angiogenesis Via NLRP12‐ASC‐Caspase‐8 Inflammasome‐Mediated Endothelial Pyroptosis
Authors: Li Yonghao , Sun Yimeng , Xie Dasen , Chen Hui , Zhang Qi , Zhang Shaochong , Wen Feng , Ou Jing‐Song , Zhang Min , Su Lishi , Li Xuri , Wen Wei‐Ping , Chi Wei 
Published: November 2024

AbstractPathological ocular angiogenesis is a significant cause of irreversible vision loss and blindness worldwide. Currently, most studies have focused on the angiogenesis factors in ocular vascular diseases, and very few endogenous anti‐angiogenic compounds have been found. Moreover, although inflammation is closely related to the predominant processes involved in angiogenesis, the mechanisms by which inflammation regulates pathological ocular angiogenesis remain obscure. In this study, a vascular endothelial cells (VECs)‐specific anti‐angiogenic factor is identified, apoptosis signal‐regulating kinase 1(ASK1)‐interacting protein‐1 (AIP1) as a key pathogenic regulator in a typical ocular angiogenesis model, oxygen‐induced retinopathy (OIR), using single‐cell RNA sequencing. It is demonstrated that AIP1 inhibited pathological angiogenesis by preventing a particular inflammatory death pathway, namely pyroptosis, in retinal VECs. The assembly of a noncanonical inflammasome is further uncovered, the NLRP12–ASC‐caspase‐8 inflammasome, which is promoted by decreased AIP1 in OIR. This inflammasome elicited gasdermin D (GSDMD)‐dependent endothelial pyroptosis, which in turn promoted the release of vascular endothelial growth factor (VEGF) and interleukin (IL)‐1β. Suppression of NLRP12–CASP8–GSDMD axis and AIP1 upregulation reduced VEGF signaling, limiting new vessel formation. These findings reveal a previously uncharacterized inflammatory angiogenic process involving VECs pyroptosis‐inducing retinal neovascularization, paving the way for promising therapeutic avenues targeting angiogenesis via AIP1 or pyroptosis.
Nonlinear Stress‐Induced Transformations in Collagen Fibrillar Organization, Disorder and Strain Mechanisms in the Bone‐Cartilage Unit
Authors: Badar Waqas , Inamdar Sheetal R. , Fratzl Peter , Snow Tim , Terrill Nicholas J. , Knight Martin M. , Gupta Himadri S. 
Published: November 2024

AbstractBy developing a 3D X‐ray modeling and spatially correlative imaging method for fibrous collagenous tissues, this study provides a comprehensive mapping of nanoscale deformation in the collagen fibril network across the intact bone‐cartilage unit (BCU), whose healthy functioning is critical for joint function and preventing degeneration. Extracting the 3D fibril structure from 2D small‐angle X‐ray scattering before and during physiological compression reveals of dominant deformation modes, including crystallinity transitions, lateral fibril compression, and reorientation, which vary in a coupled, nonlinear, and correlated manner across the cartilage‐bone interface. A distinct intermolecular arrangement of collagen molecules, and enhanced molecular‐level disorder, is found in the cartilage (sliding) surface region. Just below, fibrils accommodate tissue strain by reorientation, which transitions molecular‐level kinking or loss of crystallinity in the deep zone. Crystalline fibrils laterally shrink far more (20×) than they contract, possibly by water loss from between tropocollagen molecules. With the calcified plate acting as an anchor for surrounding tissue, a qualitative switch occurs in fibrillar deformation between the articular cartilage and calcified regions. These findings significantly advance this understanding of the complex, nonlinear ultrastructural dynamics at this critical interface, and opens avenues for developing targeted diagnostic and therapeutic strategies for musculoskeletal disorders.
Bio‐Inspired Neuromorphic Sensory Systems from Intelligent Perception to Nervetronics
Authors: Boahen Elvis K. , Kweon Hyukmin , Oh Hayoung , Kim Ji Hong , Lim Hayoung , Kim Do Hwan 
Published: November 2024

AbstractInspired by the extensive signal processing capabilities of the human nervous system, neuromorphic artificial sensory systems have emerged as a pivotal technology in advancing brain‐like computing for applications in humanoid robotics, prosthetics, and wearable technologies. These systems mimic the functionalities of the central and peripheral nervous systems through the integration of sensory synaptic devices and neural network algorithms, enabling external stimuli to be converted into actionable electrical signals. This review delves into the intricate relationship between synaptic device technologies and neural network processing algorithms, highlighting their mutual influence on artificial intelligence capabilities. This study explores the latest advancements in artificial synaptic properties triggered by various stimuli, including optical, auditory, mechanical, and chemical inputs, and their subsequent processing through artificial neural networks for applications in image recognition and multimodal pattern recognition. The discussion extends to the emulation of biological perception via artificial synapses and concludes with future perspectives and challenges in neuromorphic system development, emphasizing the need for a deeper understanding of neural network processing to innovate and refine these complex systems.
MGAT4A/Galectin9‐Driven N‐Glycosylation Aberration as a Promoting Mechanism for Poor Prognosis of Endometrial Cancer with TP53 Mutation
Authors: Zhu Zhen , Sun Jingya , Xu Weiqing , Zeng Qinghe , Feng Hanyi , Zang Lijuan , He Yinyan , He Xiao , Sheng Na , Ren Xuelian , Liu Guobin , Huang He , Huang Ruimin , Yan Jun 
Published: November 2024

AbstractEmerging evidence recognizes aberrant glycosylation as the malignant characteristics of cancer cells, but little is known about glycogenes’ roles in endometrial carcinoma (EC), especially the most aggressive subtype carrying TP53 mutations. Using unsupervised hierarchical clustering, an 11‐glycogene cluster is identified to distinguish an EC subtype associated with frequent TP53 mutation and worse prognosis. Among them, MGAT4A (alpha‐1,3‐mannosyl‐glycoprotein 4‐β‐N‐acetylglucosaminyltransferase A) emerges as the most consistently overexpressed glycogene, contributing to EC aggressiveness. In the presence of galectin‐9, MGAT4A increases EC cell proliferation and invasion via promoting glucose metabolism. N‐glycoproteomics further revealed GLUT1, a glucose transporter, as a glycoprotein modified by MGAT4A. Binding of galectin‐9 to the MGAT4A‐branched N‐glycan on GLUT1 enhances its cell membrane distribution, leading to glucose uptake increase. In addition, oncogenic mutations of TP53 gene in EC cells upregulate MGAT4A expression by disrupting the regulatory oversight exerted by wild‐type p53 on tumor‐suppressive miRNAs, including miR‐34a and miR‐449a/b. The findings highlight a new molecular mechanism involving MGAT4A‐regulated N‐glycosylation on the key regulator of glucose metabolism in p53 mutants‐driven EC aggressiveness, which may provide a strategic avenue to combat advanced EC.