bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uji Hayati Lima Jenis Minuman Kemasan Gelas dengan Hewan Uji Daphnia Magna dan Mencit Jantan (Mus musculus)
Authors: Surtikanti Hertien Koosbandiah , . Hernawati , Frisda Diah , Hidayah Muhamad Taufiq 
Published: May 2018

Lima jenis minuman yang terpilih yaitu panther, meico, teh zeggar, degan, dan teh bukit sudah dilakukan uji hayati. Salah satu untuk pengujian kualitas minuman tersebut, yaitu uji hayati dengan menggunakan neonate Daphnia magna (berumur <24 jam) dan mencit jantan (Mus musculus). Pengujian menggunakan D. magna, dilakukan dalam dua tahap yaitu Range Finding test (RFT) dan Range Definitive Test (RDT), sementara uji hayati mencit jantan galur Deutschland Denken Yoken (DDY) dilakukan dengan Rancangan Acak Lengkap, dua faktorial dengan 18 kelompok perlakuan. Pengambilan sampel darah mencit jantan diambil pada bagian ekor hewan dan diperiksa dengan menggunakan metode strip dan glucometer autocheck. Hasil RFT menunjukan 50% kematian neonate D. magna terdapat pada pengenceran 10-100%. Hasil analisis menunjukkan nilai LC50-24h untuk minuman Panther (P), Meico (M), Teh Bukit (B), Teh Zegar (Z) dan Degan (D). berturut-turut adalah 39,99; 51,5; 40,9; 40,93; dan 49,74%. Hasil uji hayati menggunakan mencit jantan, terjadi kenaikan berat badan yang signifikan pada saat diberi Z, D dan B. Kenaikan kadar gula darah mencit jantan signifikan pada waktu perlakuan selama dua dan tiga minggu dengan P, M, B, Z dan D. Hal ini disebabkan kadar gula minuman dapat meningkatkan kadar gula darah. Dapat disimpulkan bahwa kelima sampel minuman tersebut bersifat toksik, karena nilai LC50 kurang dari 50% (hasil uji D. magna) dan dapat meningkatkan kadar gula darah pada mencit jantan.
Is a decrease of grip strength associated with community mobility restriction in dynapenic older women?
Authors: Blamoutier Margaux , Boissy Patrick , Brière Simon , Faucher Geneviève , Lauzé Martine , Duval Christian 
Published: May 2018

AbstractAimsAbsolute grip strength (aGS) measures are not only used to detect dynapenia, but can also provide a robust indicator of functional impairments such as mobility limitations. Mobility limitations can impact community mobility. The main objective of this study was to investigate whether dynapenia status measured with aGS can be used as a predictor of the level of community mobility measured by Global Positioning System (GPS) and the Life‐Space Assessment questionnaire (LSA) in healthy older adults. It has been shown that body weight related grip strength (GS/BW) is also a clinical predictor of functional limitation. The secondary objective of the study was to assess the relationship between the community mobility and the GS/BW.Method and resultsThe population studied (n=62) was composed of a dynapenic group of women (aged 66.4 ± 4.8) according to an aGS threshold of ≤ 19.9kg and an age‐matched group of women (aged 66.1 ± 5.2) with no detectable dynapenia. Clinical and laboratory evaluations were conducted to measure functional capacity tests, body composition and respiratory capacity. Body weigth related to grip strength (GS/BW) was computed. During 12 days, each participant wore a GPS receiver unit with a data logging =−.67) compared system during waking hours. Transit distance in vehicle per day, Transit distance on foot per day and Ellipse area were extracted from the time series of GPS data (longitude, latitude) collected at 1 Hz. The Life space was assessed using a questionnaire. A Wilcoxon test was used to compare the 2 groups for the community mobility measures. Then, data of the 2 groups were pooled to assess the relationship between GS/BW and community mobility measures. A Spearman correlation was used. The dynapenic group had indeed lower aGS (z=−5.3, p≤.05, r=−.67) and GS/BW (z=−5.3, p≤.05, r=−.67)compared to the non‐dynapenic group. Furthermore, we found a lower performance to the step test (z=−2.5, p=.011, r=−.32) and lower walking speed (z=−2.1, p=033, r=−.27) for the dynapenic group. However, no significant differences (Wilcoxon signed‐ranks test) were found for community mobility measures with the GPS and the LSA between the two groups. There were significant positive relationships between the GS/BW and one leg stand test (r=.353, p=0.005), step test (r=.409, p=0.001) and walking speed (r=.428, p=0.001). No significant relationship (Spearman correlation test) was found for the GS/BW and community mobility measures with the GPS and the LSA.ConclusionsThis study confirms that aGS and GS/BW are good indicators of mobility limitations measured with clinical and laboratory evaluations. However, grip strength alone should not be considered as an indicator of community mobility restriction in an older adult dynapenic population.
Sobre la noción de información y algunas implicaciones en el ámbito psicosocial
Authors: Builes Isabella 
Published: May 2018

<p>La noción de información es esencial para la teoría de la individuación de Gilbert<br />Simondon. Este autor se distancia de las concepciones tradicionales sobre la información dado que estas la consideran medible y controlable. Además, una posible implicación de esta sustancialización en las teorías tradicionales es que, en la sociedad actual, la información se utiliza, en conjunto con la comunicación, para controlar y manipular los sistemas sociales, y en este sentido, puede ir en vías de la alienación de los sujetos. Profundizar en este concepto desde la perspectiva de Simondon nos permite observar algunas de sus implicaciones en el ámbito psicosocial. Para ello, tenemos en cuenta los conceptos de amplificación, transducción, modulación, organización, metaestabilidad, significación y transindividualidad. Por último, proponemos que el proceso de individuación guarda una relación de continuidad con la adaptación (biológica y psicológica), entendida como una operación específica de la cual se sirve la transducción para resolver las tensiones en los seres vivientes, incluyendo allí al ser humano.</p>
Eficácia vertical e horizontal das decisões no sistema espanhol de Controle Concentrado de Normas
Authors: Freitas Juliana 
Published: May 2018

Diante da imposição constitucional de se preservar o respeito ao tratamento igualitário àqueles que se situam em relações jurídicas idênticas, surge a necessidade de se fundamentar objetiva e razoavelmente os eventuais tratamentos jurisdicionais diferenciados. Assim, torna-se imperiosa a necessidade de os juízes buscarem elementos objetivos que aproximam e afastam não apenas as situações fáticas, como também aquelas jurídicas – que envolvem o caso posto à sua análise – exatamente para evitar a violação ao princípio constitucional da igualdade na aplicação da lei, que ocorre quando tal igualdade não se configura nos juízos emitidos pelo Tribunal Constitucional, seja vertical ou horizontalmente.
Responsabilidade objetiva no Código de Defesa do Consumidor
Authors: Bessa Leonardo Roscoe 
Published: May 2018

Este artigo aborda a responsabilidade objetiva no Código de Defesa do Consumidor – Lei nº 8.078/90. Antes, apresenta-se uma breve trajetória histórica da teoria da culpa no direito civil do sistema civil law e elabora-se crítica à visão simplificadora no sentido de que os danos aos consumidores decorrem ou de fato ou de vício do produto ou serviço (arts. 12 a 25 da Lei nº 8.078/90). Sustenta-se que o Código de Defesa do Consumidor, ao estabelecer no art. 6º, VI, o direito básico do consumidor “a efetiva prevenção e reparação de danos patrimoniais e morais”, instituiu cláusula geral de responsabilidade objetiva para as relações de consumo. Por fim, é feita uma análise dos aspectos polêmicos concernentes ao significado da responsabilidade objetiva na disciplina por fato e vicio do produto e serviço.
MINERAL COMPOSITION AND NUTRITIVE ANALYSIS OF BULBINE ABYSSINICA A. RICH. USED IN THE TREATMENT OF INFECTIONS AND COMPLICATIONS ASSOCIATED WITH DIABETES MELLITUS IN THE EASTERN CAPE PROVINCE, SOUTH AFRICA
Authors: Kibiti Cromwell Mwiti , Afolayan Anthony Jide 
Published: May 2018

Background: B. abyssinica is a succulent member of the genus Bulbine (Asphodelaceae). It occurs from the Eastern Cape, through Swaziland and further north to Ethiopia. The species is used in traditional medicine to treat rheumatism, dysentery, bilharzia, cracked lips and diabetes. The tea leaf is used to treat cough, vaginal and bladder problems. Whereas B. abyssinica has ethno medicinal value, not much data concerning its phytonutrient, macro and micro element composition can be found in literature.
Materials and Methods: Therefore, the present study was undertaken to determine the nutritional quantitative composition of the plant using standard procedures.
Results: The proximate analysis revealed the carbohydrate, crude fibre, moisture, ash, crude protein and crude fat contents as 74.8%, 8.9%, 8.8%, 8%, 7.7% and 0.6%, respectively. The species showed high levels of oxalates and phytic acids, moderate levels of alkaloids, flavonoids, saponins and phenols, while tannins were in low levels. Vitamin A, C and E contents were 12, 12.3 and 22.1 mg/100g, respectively. Amongst the mineral elements investigated, potassium and calcium were in high levels. Magnesium, iron, sodium, aluminium and phosphorus were moderately present, while manganese, zinc and copper where in low amounts. These vitamins and mineral elements were within their recommended daily allowance in humans.
Conclusion: The amount of these phytochemicals suggests the plant can serve as nutritional supplements which are vital in maintaining good health status. These findings also suggest the potential role of B. abyssinica in the treatment of infections and some chronic diseases, especially diabetes mellitus.
BITTER HERBS OF EASTERN NIGERIA (GONGRONEMA LATIFOLIUM, VERNONIA AMYGDALINA AND VITEX DONIANA): A REVIEW
Authors: Chinwe U. Asuzu 
Published: May 2018

Background: The article is a review of three bitter vegetables consumed in South-eastern Nigeria (Gongronema
latifolium, Vernonia amygdalina and Vitex doniana). These vegetables are not very palatable to taste but are highly
famed because of the myriad of illnesses that they are reputed to cure and manage. The different aspects of these
vegetables reviewed are their ethnobotany, zoo pharmacology, bioactivity, phytochemistry and toxicity.
Materials and method: The literatures consulted were searched using electronic search engines (Google, Google
scholar and Pubmed). Substantial amount of literature was consulted but only those directly related to the main review
were selected.
Result: The review revealed that the three bitter vegetables possessed phytochemicals like saponins, flavonoids,
alkaloids among others that justify the claims of curing and managing many of the illnesses that traditional folks
attribute to them. From literature, antimicrobial, antinflammatory, antidiabetic, antioxidant and anti cancer activities
were attributed to these three bitter herbs. Antinutritional substances like phytate and oxalate reported in these herbs
were not regarded as harmful for human consumption because of the traditional method of processing the vegetables by
squeeze washing in several changes of water.
Conclusion: The three bitter herbs are regarded as beneficial for human consumption and the information should be
disseminated to a large audience.
Key words: V. amygdalina, V. doniana, G.
EFFECTS OF STEM-BARK EXTRACT OF OKOUBAKA AUBREVILLIE ON SOME VISCERAL ORGANS OF WISTAR RATS
Authors: Peter Achukwu U , Silas Ufelle A , Kenechukwu Onyekwelu C , Millicent Amadi N , Ngozika Achukwu O , Francis Amadi N 
Published: May 2018

Background: Over the past two decades, there has been a tremendous increase in the use of herbal medicine; however, these herbs have not been properly evaluated to ascertain their effect on the body organs.
Materials and Methods: Effects of stem bark extract of Okoubaka aubrevillie on some visceral organs were investigated in Wistar rats. For acute toxicity testing, Wistar rats (n=16), grouped into 4, (A-D) orally received graded doses of Okoubaka aubrevillie extract and deaths recorded within 24 hours. For sub-acute study, Wistar rats (n=20) grouped into 5, (A-E) orally received graded doses of Okoubaka aubrevillie extract for 31 days. Blood samples were collected from each rat through retro-orbital puncture for biochemical analysis. The liver, kidney and stomach were excised and processed for light microscopy. For toxin inhibition studies, Wistar rats (n=24) grouped into 6 (A-F), were used. Groups A-C and D-F orally received graded doses of Dichlorvos. Groups A-C further received Okoubaka aubrevillie extract while D-F received water and death records observed.
Results: For acute toxicity testing, lethal dose (LD50) of 7500 mg/kg body weight was obtained from the inverse of the log-dose. Sub-acute studies revealed significantly elevated mean body weight in group A (210 ± 4.5 gram) compared to control (178 ± 5.0 gram), (p
Total Femoral Replacement as a Salvage Operation for the Treatment of Massive Femoral Bone Loss During Revision Total Hip Arthroplasty
Authors: DeRogatis Michael J. , Issack Paul S. 
Published: May 2018

* Revision hip arthroplasty is being performed with increasing frequency in the United States. One of the major challenges during these procedures is addressing associated femoral bone loss.* Varying degrees of proximal metaphyseal and diaphyseal bone loss may be treated with reconstruction techniques involving extensively porous-coated stems, distally based modular stems, and proximal femoral replacement. When diaphyseal bone loss extends beyond the isthmus of the femur with little support for a stem, reconstruction with replacement of the entire femur, hip, and knee (total femoral replacement) may be indicated.* Total femoral replacement is best indicated for older patients with massive loss of bone stock that makes them unsuitable for less-extensive reconstruction methods. The procedure is technically demanding and is associated with a high risk of complications, including major blood loss, deep infection, dislocation, and mechanical implant failure.* In appropriately selected patients, total femoral replacement can provide a successful salvage of an otherwise unreconstructible femur. (Previously, the only options available in such cases were nonoperative treatment, resection arthroplasty, or amputation.) In several case series, total femoral replacement has demonstrated good pain relief and improved function at intermediate to long-term follow-up.
Ecological water requirements of wetlands in the middle and lower reaches of the Naoli River
Authors: Liu JianWei , Wang Tianxiang , Zhou Qiang 
Published: May 2018

Abstract
In the last few decades, the wetland area of the Sanjiang Plain in northeast China has shrunk severely. To provide a scientific basis for the protection and restoration of wetlands in the Sanjiang Plain, Landsat TM images of 13 typical years of four well-preserved and contiguous wetlands are interpreted by remote sensing technology in the Sanjiang Plain of the Naoli River Drainage Basin. According to the results of the interpretation, the calculation of the minimum and the optimal ecological water requirements of the four wetlands was carried out by combining ecology with remote sensing technology. At the same time, considering the rainfall and surface runoff at different guarantee rates, the artificial recharge of four wetlands was calculated according to the principle of water balance. The results indicate that the wetland area decreased significantly from 1984 to 2013, and natural inflow of water cannot meet the actual water requirements of wetlands. The calculated artificial recharge of the four reserves provides technical support for replenishment of wetlands in the Sanjiang Plain, and lays a good foundation for the restoration of wetland ecosystems in the Sanjiang Plain. At the same time, it also provides a good habitat for rare waterfowl.
Phycoremediation of textile wastewater using indigenous microalgae
Authors: Aragaw Tadele Assefa , Asmare Abraham M. 
Published: May 2018

Abstract
The recognition that environmental pollution is a worldwide threat to public health and environmental degradation has given rise to new initiatives for environmental restoration for both economic and ecological reasons. There are several methods to treat the dye contaminated industrial wastewater; of which biological treatment methods are economical and environmentally friendly. The bacteria and fungi remediation of dye pollutants has been well characterized over a period of more than 30 years. So, finding other biological methods in addition to bacteria and fungi is great important in the world. As a result, investigating and evaluating Phycoremediation techniques of dye wastewater (bioremediation using Microalgae) have gained a great deal of attention because of their versatility and capacity than bacteria and fungi. The aim of the research is to study Phycoremediation of Textile Wastewater Using indigenous Microalgae.
Physico-chemical parameters such as color, pH, total dissolved solid (TDS), biochemical oxygen demand (BOD) and chemical oxygen demand of the waste were determined with ASTM standard methods before and after bioremediation. Photo bioreactor systems were used for Phycoremediation treatment techniques. PH, incubation time and temperature effects were determined on a photo bioreactor treatment and optimal experimental condition was ascertained. Instrumental analytical techniques (UV-Vis, FTIR) were used to determine percent decolorizations of dye wastewater before and after bioremediation; and the actual break down of the dye functional groups.
The maximum reductions of the basic parameters; COD, BOD and TDS were obtained 91.50%, 91.90% and 89.10% respectively. The optimum operating conditions in the photo bioreactor system were found incubation time 20 days, 30°C; with 10% of inoculums at a pH of 8. Under these conditions, a maximum of 82.6% decolorization was achieved in 20 days. The experimental investigations evidently tell us algae undoubtedly have the potential to rapidly, efficiently and effectively remove dyes wastewater.
The effect of calcium on biofilm formation in dairy wastewater
Authors: Dixon M. J. L. , Flint S. H. , Palmer J. S. , Love R. , Chabas C. , Beuger A. L. 
Published: May 2018

Abstract
Biofilm formation in dairy wastewater system irrigation pipes can reduce treatment capacity, increasing maintenance and cleaning costs. Understanding the effect of different components in the wastewater on growth and yield of bacteria present could help prevent excessive build-up of biofilms. This study investigated, in aerobic and anaerobic conditions, the effect of calcium, sodium and magnesium concentrations on growth rates, yields and saturation constants of four known biofilm forming bacteria associated with the blockage of an irrigation system. The ions tested (Ca2+, Mg2+, Na+) varied growth rates with biofilm growth in the presence of calcium being significantly slower (P &lt; 0.05) than planktonic growth in sodium. Along with the slower growth, the addition of Ca2+ (up to 0.1 M) increased biofilm formation while addition over 0.5 M prevented biofilm formation. Knowing the nutritional requirements of the bacteria and the effects of the ions will be useful in predicting the growth, development and strategies in controlling biofilm formation in dairy wastewater.
Kinetic modeling of lead removal in a resin column–parameters evaluation
Authors: Rajamohan N. , Al Gharibi Amira , Rajasimman M. 
Published: May 2018

Abstract
Lead contamination of water streams, a potential threat to ecosystem, was treated using a cation exchange resin under continuous conditions in a upflow column. The optimal pH for maximum lead removal was identified through the batch experiments. Neutral pH was found to be favorable due to non-existence of competing hydrogen ions and absence of hydroxide containing precipitate formations. The effects of flow rates (4.0 to 8.0 mL/ min) and the resin bed depth (6 to 18 cm) were studied under optimal pH and fixed initial lead concentration of 50 mg/L. The breakthrough curves were plotted and analyzed in detail. Bed Depth Service Time (BDST) and Thomas model were fitted to the experimental data and the model parameters were determined. The maximum exchange capacity of the bed (q0) was determined as 14.60 mg/g at a flow rate of 4 mL/min and a bed height of 12 cm and the Thomas model constant decreased with decrease in flow rate. BDST model parameters, namely, N0 and Ka, increased with increase in flow rates. BDST proved to be a better fit compared to Thomas model under the entire range of operating conditions tested.
Prediction of Nitrated Tyrosine Residues in Protein Sequences by Extreme Learning Machine and Feature Selection Methods
Authors: Chen Lei , Wang ShaoPeng , Zhang Yu-Hang , Wei Lai , Xu XianLing , Huang Tao , Cai Yu-Dong 
Published: May 2018

Background:
Accurately recognizing nitrated tyrosine residues from protein sequences
would pave a way for understanding the mechanism of nitration and the screening of the tyrosine
residues in sequences.

Results:
In this study, we proposed a prediction model that used the extreme learning machine
(ELM) algorithm as the prediction engine to identify nitrated tyrosine residues. To encode each
tyrosine residue, a sliding window technique was adopted to extract a peptide segment for each
tyrosine residue, from which a number of features were extracted. These features were analyzed by a
popular feature selection method, Minimum Redundancy Maximum Relevance (mRMR) method,
producing a feature list, in which all features were ranked in a rigorous way. Then, the Incremental
Feature Selection (IFS) method was utilized to discover the optimal features, on which the optimal
ELM-based prediction model was built. This model produced satisfactory results on the training
dataset with a Matthews correlation coefficient of 0.757. The model was also evaluated by an
independent test dataset that contained only positive samples, yielding a sensitivity of 0.938.

Conclusion:
Compared to other prediction models that use classic machine learning algorithms as
prediction engines on the same datasets with their own optimal features, the optimal ELM-based
prediction model produced much better results, indicating the superiority of the proposed model for
the identification of nitrated tyrosine residues from protein sequences.
Hepatitis E Virus Infection During Pregnancy: The Overlooked Cause of Maternal and Fetal Mortality
Authors: Farshadpour Fatemeh , Taherkhani Sakineh , Taherkhani Reza 
Published: May 2018

Background:
Hepatitis E virus (HEV) is one the leading causes of maternal and fetal mortality.
Nevertheless, in some geographical locations, especially Egypt, despite having high frequency of
HEV seropositivity, HEV infection follows an asymptomatic or mild course during pregnancy. These
anomalous observations have distracted attention from the importance of HEV infection in pregnant
women.

Methods:
While tragic cases of HEV-infected pregnant women cannot be neglected any longer.

Conclusion:
These circumstances create a strong demand for the increasing awareness of HEV infection
through training programs, appropriate management of HEV infection among pregnant women,
routine screening of pregnant women for timely diagnosis of HEV infection, proper treatment of HEVinfected
patients, optimal preventive measures, and development of a prophylactic vaccine against HEV
infection.