bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infection-Related Mortality in Recipients of a Kidney Transplant in Australia and New Zealand
Authors: Chan Samuel , Pascoe Elaine M. , Clayton Philip A. , McDonald Stephen P. , Lim Wai H. , Sypek Matthew P. , Palmer Suetonia C. , Isbel Nicole M. , Francis Ross S. , Campbell Scott B. , Hawley Carmel M. , Johnson David W. 
Published: August 2019

Background and objectives
The burden of infectious disease is high among kidney transplant recipients because of concomitant immunosuppression. In this study the incidence of infectious-related mortality and associated factors were evaluated.

Design, setting, participants, & measurements
In this registry-based retrospective, longitudinal cohort study, recipients of a first kidney transplant in Australia and New Zealand between 1997 and 2015 were included. Cumulative incidence of infectious-related mortality was estimated using competing risk regression (using noninfectious mortality as a competing risk event), and compared with age-matched, populated-based data using standardized incidence ratios.

Results
Among 12,519 patients, (median age 46 years, 63% men, 15% diabetic, 6% Indigenous ethnicity), 2197 (18%) died, of whom 416 (19%) died from infection. The incidence of infection-related mortality during the study period (1997–2015) was 45.8 (95% confidence interval [95% CI], 41.6 to 50.4) per 10,000 patient-years. The incidence of infection-related mortality reduced from 53.1 (95% CI, 45.0 to 62.5) per 10,000 person-years in 1997–2000 to 43.9 (95% CI, 32.5 to 59.1) per 10,000 person-years in 2011–2015 (P<0.001) Compared with the age-matched general population, kidney transplant recipients had a markedly higher risk of infectious-related death (standardized incidence ratio, 7.8; 95% CI, 7.1 to 8.6). Infectious mortality was associated with older age (≥60 years adjusted subdistribution hazard ratio [SHR], 4.16; 95% CI, 2.15 to 8.05; reference 20–30 years), female sex (SHR, 1.62; 95% CI, 1.19 to 2.29), Indigenous ethnicity (SHR, 2.87; 95% CI, 1.84 to 4.46; reference white), earlier transplant era (2011–2015: SHR, 0.39; 95% CI, 0.20 to 0.76; reference 1997–2000), and use of T cell–depleting therapy (SHR, 2.43; 95% CI, 1.36 to 4.33). Live donor transplantation was associated with lower risk of infection-related mortality (SHR, 0.53; 95% CI, 0.37 to 0.76).

Conclusions
Infection-related mortality in kidney transplant recipients is significantly higher than the general population, but has reduced over time. Risk factors include older age, female sex, Indigenous ethnicity, T cell–depleting therapy, and deceased donor transplantation.

Podcast
This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2019_08_27_CJN03200319.mp3
LAND RESOURCE MANAGEMENT STRATEGY FOR THE SUSTAINABILITY OF THE UPPER WATERSHED OF PALU (Case Study of Miu Sub Watershed in Sigi Regency)
Authors: Widjajanto Danang , Hasanah Uswah 
Published: August 2019

Population growth and regional expansion has increased land needs for settlement, agriculture, and trade in the Palu watershed causing much pressure on the upper part of the watershed where Miu watershed is situated The general aim of the research was to generate strategy for sustainable land resources management in the Miu watershed as a buffer zone of the Lore-Lindu National Park. The objective of the research were 1) to predict soil erosion and sedimentation, 2) to analyze the feasibility of dominant farming systems, 3) to analyze rural development, and 4) to analyze community preference on land use priority. The erosion and sedimentation, and feasibility research was conducted through soil survey and socio-economic approach. The rural development index was determined using secondary data taken from related institution such as demography, regional structure and infra structure, and industrial-trade condition. The preferential analysis of land use priority for 10 years ahead was done using focus group discussion with farmer community leaders. The soil erosion rate was light - heavy whilst the soil erosion index was low - very high estimated by the USLE. The relationship between the river debit and suspended load at the upper and lower part of the watershed was found to follow the equation of Y= 0.001X1.366 (R2= 0.65), and Y = 0.001 X1.409 (R2 = 0.66), respectively. Three villages included Pakuli, Pandere, and Bolapapu had high index of rural development whereas low index was found in Lonca, Bangga and Tangkulowi. The high-low order of land use priority was agro forestry, cacao monoculture, fresh water fishery, wetland rice, ruminant grazing, mixed culture of rice, soy bean, cassava and maize, and poultry farming.
Impaired Awareness of Hypoglycemia Disrupts Blood Flow to Brain Regions Involved in Arousal and Decision Making in Type 1 Diabetes
Authors: Nwokolo Munachiso , Amiel Stephanie A. , O’Daly Owen , Byrne Megan L. , Wilson Bula M. , Pernet Andrew , Cordon Sally M. , Macdonald Ian A. , Zelaya Fernando O. , Choudhary Pratik 
Published: August 2019

OBJECTIVE
Impaired awareness of hypoglycemia (IAH) affects one-quarter of adults with type 1 diabetes and significantly increases the risk of severe hypoglycemia. Differences in regional brain responses to hypoglycemia may contribute to the susceptibility of this group to problematic hypoglycemia. This study investigated brain responses to hypoglycemia in hypoglycemia aware (HA) and IAH adults with type 1 diabetes, using three-dimensional pseudo-continuous arterial spin labeling (3D pCASL) functional MRI to measure changes in regional cerebral blood flow (CBF).

RESEARCH DESIGN AND METHODS
Fifteen HA and 19 IAH individuals underwent 3D pCASL functional MRI during a two-step hyperinsulinemic glucose clamp. Symptom, hormone, global, and regional CBF responses to hypoglycemia (47 mg/dL [2.6 mmol/L]) were measured.

RESULTS
In response to hypoglycemia, total symptom score did not change in those with IAH (P = 0.25) but rose in HA participants (P &lt; 0.001). Epinephrine, cortisol, and growth hormone responses to hypoglycemia were lower in the IAH group (P &lt; 0.05). Hypoglycemia induced a rise in global CBF (HA P = 0.01, IAH P = 0.04) but was not different between groups (P = 0.99). IAH participants showed reduced regional CBF responses within the thalamus (P = 0.002), right lateral orbitofrontal cortex (OFC) (P = 0.002), and right dorsolateral prefrontal cortex (P = 0.036) and a lesser decrease of CBF in the left hippocampus (P = 0.023) compared with the HA group. Thalamic and right lateral OFC differences survived Bonferroni correction.

CONCLUSIONS
Responses to hypoglycemia of brain regions involved in arousal, decision making, and reward are altered in IAH. Changes in these pathways may disrupt IAH individuals’ ability to recognize hypoglycemia, impairing their capacity to manage hypoglycemia effectively and benefit fully from conventional therapeutic pathways to restore awareness.
Evaluation of the Effect of Follower Jammer on the Mobile Bluetooth Network
Authors: Abdullah Abdulqadir Ismail , Al-Dalawie Adil Hussein 
Published: August 2019

Bluetooth wireless communication technology has spread rapidly in the past 20 years. It has made life much easier with all the devices that use Bluetooth technology around us such as mobile phones, laptops, and watches. With all the good and useful applications of Bluetooth technology, it has been used in harmful and bad ways such as cheating in an examination. In this article, parameter design considerations have been discussed for a follower jammer to interrupt a Bluetooth network, especially when it is used in unauthorized way. The effects of the follower jammer were studied and tested. The effects were calculated for time and jamming-over-signal ratio for three different distances (1, 5, and 10 m). The testing showed that the follower jammer designed was successful in disrupting the Bluetooth signal.
Dietary Kaolin Clay in Pre- and Post-Weaned Piglets and Its Influence on Haematological and Biochemical Parameters, and Intestinal Microflora Status
Authors: Bederska-Łojewska Dorota , Pieszka Marek 
Published: August 2019

Abstract
The main aim of the study was to evaluate the effect of two experimental feed additives based on kaolin clay on piglets’ health and microbiota status. The experiment was divided into 2 parts – from birth up to weaning (28 d) and later after weaning up to 70 d of age. Eighteen litters of piglets with sows were divided into 3 groups: control, A and B. The animals from experimental group A were supplemented with kaolin clay (100%), while the animals from group B received kaolin clay enriched with dried pomace of chokeberry and fructooligosaccharides. We noted an improvement in blood parameters related to anaemia, which were significantly better in the experimental group B in comparison to the control and A group (haematocrit; 37.67 and 37.40 vs 39.65%; P<0.0005). The dietary treatments during pre-weaning time influenced the increase of the E. coli strain in the colon and jejunum and had no effect on lowering the population of Salmonella and Shigella in the colon. However, it affected the quantity of Salmonella and Shigella in the jejunum in both A and B (-20%) groups. The rise of commensal bacteria Lactobacillus (+2.3 and +10%) and Bacteroides (+5.82 and +5.11%) was observed in groups A and B in the colon. This effect was not present in the jejunum.
Genetic Variability in the Loci of FABP4, PPARγ and SCD Genes of Sheep Breeds Raised for Different Purposes
Authors: Kucharski Mirosław , Kaczor Urszula , Piórkowska Katarzyna 
Published: August 2019

Abstract
The present study was undertaken to analyse the genetic variation in coding sequences, splicing sites and regulatory sequences of FABP4, PPARγ and SCD genes in five breeds of sheep raised in Poland with different purposes: meat (Suffolk, Ile de France), dairy/prolific (Olkuska sheep, Kołuda) and primitive breeds (Polish Mountain Sheep). To identify genetic variability HRM-PCR, sequencing and PCR-RFLP method were used. Determining the genetic structure of the mentioned genes revealed six SNPs: FABP4 – c.73 + 13A>T and c.348 + 85G>A, PPARγ – c.391 – 66C>T (c.481 – 66C>T) and c.529 + 27G>C (c.619 + 27G>C), SCD – c.*945G>A and c.*1116A>G. For the c.*1116A>G SNP, a potential association with specific sheep body type and breeding purpose was found. In turn, the substitution c.*945G>A located in the regulatory region of the 3'-UTR of the Ovis aries SCD gene was identified for the first time. Based on the relationship demonstrated between sheep body constitution and productive type (dairy, meat) and the polymorphism of the SCD gene, further research is needed. The correlation between c.*1116A>G polymorphism and growth rate, slaughter and carcass value as well as meat quality of lambs needs to be studied in more detail. Such studies may lead to more effective selection processes in sheep breeding in the future.
The Genetic Basis of Piebald Coat Colour in Hucul Horses in the Context of White Markings and Crypto-Tobiano as a Breeding Problem in Poland
Authors: Pasternak Marta , Krupiński Jędrzej , Gurgul Artur , Bugno-Poniewierska Monika 
Published: August 2019

Abstract
The aim of the study was to analyse the genetic basis of piebald coat colour in Hucul horses and to verify their coat colour in breeding records. Tests were performed with DNA purified from the whole blood samples of 242 Hucul horses with different coat colour patterns. DNA was analysed to identify an inversion in ECA3 (PCR). The results confirmed that the inversion on ECA3 is a direct factor determining piebald (tobiano) colour in the analysed Hucul horses. No inversion was observed in any of the solid coloured horses, but it was present in all the piebald ones. It was also identified in 18% (11 of 61) of the horses from the group of horses qualified in the passport as solid coloured with white markings. In fact, these horses had the tobiano gene that is phenotypically identifiable as crypto-tobiano, which may give the false impression of having white markings and lead to error when describing a horse. This is an important issue, in particular with regard to the breed standard, which eliminates Hucul horses with white markings from breeding.
The Physiological Aspects, Technique and Monitoring of Slaughter Procedures and their Effects on Meat Quality – A Review
Authors: Borzuta Karol , Lisiak Dariusz , Janiszewski Piotr , Grześkowiak Eugenia 
Published: August 2019

Abstract
The aim of the paper was a review of the scientific achievements in physiological stunning and slaughtering mechanisms, control methods of consciousness and their effect on meat quality. Special attention was paid to neurophysiological phenomena that accompany the process of depriving consciousness before animal deaths using mechanical, electrical and gas stunning methods. These mechanisms are associated with cerebral hypoxia or ischemia or depolarization, acidification and the destruction of cerebral neurons. Such effects can be caused by shock waves, bleeding, electric fields, reduction or arrest of the circulation of blood in the brain, high CO2 level or low O2 level in inhaled air or by the mechanical damage of neurons. Some of the stunning methods cause immediate and some gradual consciousness loss. An important factor in the animals’ slaughtering process is the estimation of their consciousness level before bleeding. The indicators of consciousness during mechanical, electrical and gas stunning are discussed within this paper. It is pointed out that at least 2 indicators should be used when estimating animals’ consciousness after stunning, e.g. phonic and clonic limb movements and lack of breathing. Ten indicators to control the consciousness were described. The effect of stunning on meat quality is also discussed. It was found that the impact of this process on the quality is not clear. However, the prevailing view is that electric stunning causes effusions and blood haemorrhages in meat. Whereas gas stunning with a CO2 mixture diminishes the risk of PSE meat. Despite numerous scientific research on the slaughter process there is still deficiency in knowledge on losing consciousness mechanisms and feeling pain. It might be useful to extend the knowledge concerning neurotransmitters and use of magnetic resonance in future studies.
The Effect of Fermented Soybean Meal on Performance, Biochemical and Immunological Blood Parameters in Turkeys
Authors: Chachaj Robert , Sembratowicz Iwona , Krauze Magdalena , Stępniowska Anna , Rusinek-Prystupa Elżbieta , Czech Anna , Matusevičius Paulius , Ognik Katarzyna 
Published: August 2019

Abstract
The aim of the present study was to assess the effect of different levels of fermented soybean meal on growth performance, intestinal morphology, metabolic indicators, and immunity in turkeys. The material for the study consisted of day-old BIG 6 turkeys raised to the age of 112 days. The experiment was carried out on 800 turkey hens (10 replications of 20 individuals each), assigned to 4 experimental groups of 200 birds each. The feed for the control group (FSBM0) was a standard mix without fermented soybean meal. For turkeys from groups FSBM7, FSBM9 and FSBM10 the diet contained 70, 90 or 100 g fermented soybean meal (FSBM) per kg of feed, respectively. The study showed that including fermented soybean meal in feed for turkeys at 7% improved intestinal histology and stimulated the immune and antioxidant systems. The use of higher level of FSBM (9% and 10%) in the diet of the turkeys improved growth performance and had a beneficial effect on the histology of the small intestine. The dietary inclusion of 10% FSBM had beneficial effect on red-blood-cell parameters, but caused negative impact on liver and kidney function (an increase of aminotransferases activity, content of glucose and creatinine in turkeys’ blood). Ten percent share of FSBM in feed contributed to an adverse intensification of oxidation and inflammatory reactions which were reflected by an increase of malonyldialdehyde, lipid peroxides level and proinflammatory inteleukine-6 contents.
Pre-Slaughter Handling Implications on Rabbit Carcass and Meat Quality – A Review
Authors: Składanowska-Baryza Joanna , Stanisz Marek 
Published: August 2019

Abstract
Procedures that result in poor welfare of animals are unacceptable to many people. Consumers have become demanding about the quality of meat, but are also concerned about animal welfare during the production, transport, and slaughter stages. There is a well-known, clear relationship between animal welfare and the quality of animal products. Improper handling of farmed animals contributes to low meat quality. This rule refers to all animals raised for meat, including rabbits. Fasting, loading for transport, long distance transport in difficult environmental conditions, improper stocking density, lying down during transport, lairage, and stunning methods may negatively affect the quality of rabbit meat. A general conclusion from reviewed scientific articles is that many pre-slaughter factors influence the physiological and productive measurements of rabbits, through the effect on their welfare. Because of the complexity of the rabbit meat production chain, the possibility of excluding all the defined stressors is limited.
Herbal Medicine Additives as Powerful Agents to Control and Prevent Avian Influenza Virus in Poultry – A Review
Authors: Gado Ahmed R. , Ellakany Hany F. , Elbestawy Ahmed R. , Abd El-Hack Mohamed E. , Khafaga Asmaa F. , Taha Ayman E. , Arif Muhammad , Mahgoub Samir A. 
Published: August 2019

Abstract
The complicated epidemiological situation of avian influenza viruses (AIV) caused by continuous emergence of new subtypes with failure of eradication, monitoring and vaccination strategies opens the door to alternative solutions to save the status quo and prevent new disasters for the poultry industry. Using of synthetic antiviral drugs such as neuraminidase and hemagglutinin inhibitors has been limited due to development of drug resistance and expensive commercial application. One of the most promising alternatives is herbal products and botanicals. This review presents a comprehensive and specialized view of in vivo studies of herbal plants in poultry species. Many herbal extracts as Nigella sativa oil, Astragalus, Cochinchina momordica and Sargassum pallidum polysaccharides proved very effective as adjuvants for AIV vaccines. Another beneficial role of herbs is enhancement of host response to vaccination with further better prevention of infection and easier control. For enumeration not inventory, this is best achieved with the use of virgin coconut oil, Echinacea purpurea, Ginseng stem-and-leaf saponins (GSLS), Astragalus polysaccharides (APS), Myrtus communis oil, Garlic powder, Turmeric, Thyme and Curcumin. This review aimed to evaluate most of the in vivo studies performed on poultry species as a step and a guide for scientists and field practitioners in establishment of new effective herbal-based drugs for prevention and control of AIV in poultry.
Multicriteria Decision-Making in Complex Quality Evaluation of Ladies Dress Material
Authors: Misra Srabani , Salacova Jana , Militky Jiri 
Published: August 2019

Abstract
Quality is the essence of any product for consumer satisfaction. However, different people have different perception of quality. Eventually the definition of quality varies from product to product and thus it is much more complex in textile clothing material evaluation. The end use application of a specific clothing material determines what should be the parameters of quality evaluation. Thus, the evaluation based on subjective assessment becomes unpredictable and unquantifiable. Quality for dress materials is not simply a physical parameter but something called as psycho-physical parameter. In recent times, many objective evaluation systems have been developed to evaluate the apparel grade textile materials with regard to their quality parameters. However, the evaluation does not involve enough statistical treatment of data so as to obtain a parametric weighted characterization of complex quality. The current work deals with parametric approach to complex quality evaluation based on multicriteria decision-making approach for ladies dress materials. The ladies dress materials are of numerous varieties and choices across the globe. The selection and marketing of these kinds of textile materials need to be given proper emphasis as it depends not only on physical parameters but also on climate, geography, ethnic group, market trend, age group, gender, and many such complex parameters, which are not quantifiable in absolute terms. In this study, woven fabrics used for ladies dress materials are collected from the market and they were evaluated for the consumer-oriented property parameters. A parametric approach is adopted to quantify the overall quality of these dress materials. Various objective techniques were used to evaluate the comfort and esthetic parameters. A complex quality index (CQI) was estimated with weighted combination of all the contributing parameters and total quality index was calculated. Selected consumers with different education level, age, and gender were interviewed to get a statistic of their opinion about quality parameters preferred by them. This complex quality index/degree of satisfaction shows very high correlation with subjective judgment. A CQI can be evaluated for each kind of clothing material looking into their applications.
Implantation and pregnancy outcome of Sprague-Dawley rats exposed to pirimiphos-methyl
Authors: Oyesola Tolulope , Iranloye Bolanle , Adegoke Olufeyi 
Published: August 2019

Abstract

Objective. This study was designed to investigate the effect of sublethal doses (10, 60, and 120 mg/kg of pirimiphos-methyl on implantation and pregnancy in female Sprague-Dawley rats. Pirimiphos-methyl is a pesticide widely used worldwide, especially in Africa to protect food against pests and has gained widespread acceptance.

Methods. Pregnant Sprague-Dawley rats used for this study had access to food and water ad libitum and were divided into a control group and three experimental groups based on dose of chemical given. The pregnant rats were given pirimiphos-methyl orally on days 1–5, 1–7, 7–18th day of gestation and from day 1 to term. Implantation studies were carried out on days 6 and 8 of pregnancy, while the fetal parameters were ascertained on day 19 of pregnancy and at term. Serum levels of progesterone and estradiol were measured on days 6, 8 and 19 of pregnancy.

Results. Sublethal administration of pirimiphos-methyl showed decreased number of implantation sites on days 6 and 8, fetal weight, crown-to-rump length, length of umbilical cord and placenta weight (day 19), birth weight, litter size and total number (at term) in rats administered with pirimiphos-methyl when compared with control.

Conclusion. Administration of pirimiphos-methyl resulted in a reduced implantation rate due to decreased uterine receptivity caused by an imbalance in the level of estradiol and progesterone and impaired reproductive outcome during pregnancy.