bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of 2- vs. 3-Minute Interrepetition Rest Period on Maximal Clean Technique and Performance
Authors: Ammar Achraf , Riemann Bryan L. , Abdelkarim Osama , Driss Tarak , Hökelmann Anita 
Published: August 2018

Abstract
Ammar, A, Riemann, BL, Abdelkarim, O, Driss, T, and Hökelmann, A. Effect of 2- vs. 3-minute interrepetition rest period on maximal clean technique and performance. J Strength Cond Res 34(9): 2548–2556, 2020—Currently, it is widely accepted that adopting a long rest period (3–5 minutes) during maximal strength and power exercise is of importance in reducing acute fatigue and maintaining power and technique proficiency. However, despite the fact that weightlifting is an example of maximal strength exercise, only 2 minutes are officially allowed when athletes attempt 2 successive lifts. The purpose of this study was to compare 3- vs. 2-minute intermaximal repetition rest periods (IMRRPs) on performance, rate of perceived exertion (RPE), technical efficiency, and power production during 2 successive maximal repetitions of clean & jerk (C&J). Nine elite weightlifters (age: 24.4 ± 3.6 years, body mass: 77.2 ± 7.1 kg, height 176.0 ± 6.4 cm, and 1 repetition maximum C&J: 170.0 ± 5.0 kg) performed 2 separate testing sessions using 2-minute IMRRP (IMRRP-2) and 3-minute IMRRP (IMRRP-3), in a randomized order, while barbell kinematics and kinetics were recorded. Results showed that the longer IMRRP-3 minutes led to the maintenance of clean technique (from the first to the second repetition) evidenced by a 1.86% lower decline in peak vertical displacement (p = 0.03) and attenuation of increased peak horizontal displacements with a 1.74% (p = 0.03) less backward movement during the first pull, a 3.89% (p = 0.008) less forward movement during the second pull, and a 4.7% (p = 0.005) less backward movement during the catch phase. In addition, attenuation of peak velocity (2.22%; p = 0.02), peak vertical ground reaction force (1.70%; p = 0.03), and peak power (2.14%; p = 0.02) declines were shown using IMRRP-3 compared with IMRRP-2. Increasing IMRRP from 2 to 3 minutes was also shown to decrease RPE values (8.02%; p = 0.008) and to enhance supramaximal C&J performance (1.55%; p = 0.003). The results of this study suggest 3 minutes to be the most advantageous IMRRP in terms of maintaining technical efficiency, power output, reducing fatigue perception, and enhancing performance in elite weightlifters.
Effect of Unstable Loads on Stabilizing Muscles and Bar Motion During the Bench Press
Authors: Lawrence Michael A. , Ostrowski Stephanie J. , Leib Daniel J. , Carlson Lara A. 
Published: August 2018

Abstract
Lawrence, MA, Ostrowski, SJ, Leib, DJ, and Carlson, LA. Effect of unstable loads on stabilizing muscles and bar motion during the bench press. J Strength Cond Res 35(2S): S120–S126, 2021—Unstable loads are anecdotally used to increase muscle stabilizer strength and utilization; however, there is little evidence to support these claims. Twelve male powerlifters (age 28.6 ± 5.2 years, body mass 105.6 ± 14.5 kg, lifting experience 9.8 ± 6.0 years, and bench press 5 repetition maximum [5RM] 133.6 ± 30.9 kg) pressed their 5RM in one stable condition with a standard barbell, and 3 unstable conditions using a flexible barbell with weights suspended from elastic bands. Mean integrated muscle activity for each repetition of the stabilizers and prime movers were measured. A Lyapunov exponent and sample entropy indicated unstable loads were less predictable and more variable in the superior/inferior direction, thus more challenging to control, despite decreased loads. The main finding was increased bicep activity in all unstable conditions (light bands and plates, +57%; mini bands and plates, +67%; and mini bands and kettlebells, +88%). Although less weight was used in the unstable 5RMs, most stabilizer muscle activity was not different between conditions, suggesting that the amount of weight used during unstable load training (up to 32.3% less load) may be limited by the ability of stabilizer muscles to control the load.
Numerical Simulation and Laboratory Testing Verification on the Performance of an Asphalt Pavement Seal Coat with Superficially Permeating and Solidifying Properties
Authors: Liang Hehao , Wang Duanyi , Wang Gang , Li Danning , Xu Chi , Liang Xiayi 
Published: August 2018

Abstract
In recent years, preventive maintenance has been used widely to solve the problem of early-stage asphalt pavement damage. However, conventional preventive maintenance treatments cannot effectively prevent rutting or damage resulting from the leakage of diesel fuel to the pavement. In this context, numerical simulations of uniaxial penetration tests were conducted with the Discrete Element Model to evaluate the feasibility and effectiveness of pavement surface solidification with a special seal coat. Standard viscosity tests on mixtures of waterborne epoxy resin and emulsified asphalt used as the Permeating and Solidifying Seal Coat (PSSC) material were performed, and uniaxial penetration tests and accelerated loading tests were conducted on asphalt mixture specimens with and without the PSSC. The optimum proportion of PSSC material was determined and its permeability, rutting resistance, diesel fuel corrosion resistance, and durability were evaluated. The results of this study indicate that the superficially solidified pavement with PSSC can effectively enhance rutting resistance and diesel fuel corrosion resistance and can provide more durable skid resistance and better antistripping performance than conventional preventive maintenance treatments. Therefore, the PSSC could be considered a new generation of preventive maintenance treatments for asphalt pavements.
Sport Specialization and Risk of Overuse Injuries: A Systematic Review With Meta-analysis
Authors: Bell David R. , Post Eric G. , Biese Kevin , Bay Curtis , Valovich McLeod Tamara 
Published: August 2018

CONTEXT:
Sport specialization is theorized to increase the risk of sustaining overuse musculoskeletal injuries.

OBJECTIVE:
To complete a systematic review and meta-analysis of the literature to determine if sport specialization is associated with overuse musculoskeletal injuries.

DATA SOURCES:
An electronic search was conducted using the search terms “specialization,” “year-round,” “overuse,” “repetitive stress,” “injury,” “young,” “pediatric,” and “sports.”

STUDY SELECTION:
Studies were included if their population was ≤18 years of age, if they compared athletes with high or single-sport specialization with athletes with low or multisport specialization, and focused on overuse injuries.

DATA EXTRACTION:
Of the 12 articles that were identified for full-text review, 5 studies met all the inclusion criteria. Four studies provided adequate data for the meta-analysis. Quality scores on the modified Downs and Black scale ranged from 69% to 81%.

RESULTS:
Athletes with high specialization were at an increased risk of sustaining an overuse injury compared with athletes with low (pooled relative risk [RR] ratio: 1.81; 95% confidence interval [CI]: 1.26–2.60) and moderate (pooled RR: 1.18; 95% CI: 1.05–1.33) specialization. Athletes with moderate specialization were at a higher risk of injury compared with athletes with low specialization (RR: 1.39 [95% CI: 1.04–1.87]).

LIMITATIONS:
Four of the 5 studies included in this systematic review were included in the meta-analysis because of the lack of access to the original data set for 1 article.

CONCLUSIONS:
Sport specialization is associated with an increased risk of overuse musculoskeletal injuries (Strength of Recommendation Taxonomy grade: B).
Who is a Subject and what is Her Position?
Authors: Sheedy Matt K. 
Published: August 2018

Merinda Simmons's Changing the Subject offers an important and critical reading of a variety of slave and diaspora narratives that focus on Afro-Caribbean women, pushing the boundaries of contemporary scholarship on narrative, gender, and post-colonial theory with insights from migration, diaspora, and identity studies, along with post-structural theory. While Simmons provides a rich re-reading of four historical novels that deal with these topics, her critical analysis does not address the ways in which the subject positions of differently situated bodies, past and present, are constituted by the structural constraints that surround them and must respond in ways that call out for a political position. Moving beyond Simmons's focus on discourse, I ask how scholars might address such concerns without undermining their own theoretical rigour.
Type 3 VWD and an inhibitor to VWF: Challenges in diagnosis
Authors: Jenkins S. , Carcao Manuel , Bouskill Vanessa 
Published: August 2018

Abstract
Developing an inhibitor to von Willebrand factor (VWF) is extremely uncommon. Consequently, patients with von Willebrand disease (VWD) tend not to be routinely evaluated for inhibitors, leading to the possibility of delay in inhibitor diagnosis. We present such an occurrence to raise awareness, with a view to avoiding such delays. A 1-year-old male with no family history of bleeding disorders or parental consanguinity presented with a tongue bleed lasting three days. Investigations confirmed a diagnosis of Type 3 VWD. Over the next few months, the patient received seven exposures to Humate-P (a plasma derived FVIII containing von Willebrand factor concentrate), but developed an anaphylactic reaction necessitating adrenalin and Benadryl (diphenhydramine). The reaction quickly abated and did not recur with further exposure to Humate-P. In 2013, due to recurrent epistaxis and tonsillar bleeding, the patient was commenced on prophylaxis receiving Humate-P 50 RCo U/kg twice weekly. Despite this regimen, he continued to experience recurrent epistaxis, leading to escalation of prophylaxis to 3/week. In November 2014, he showed persistent tonsillar bleeding, despite having received two doses of Humate-P (each 40 RCo U/kg) in the previous 12 hours. Testing revealed reduced VWF:Ag, VWF:RCo and FVIII:C recoveries. Further testing revealed an anti-VWF antibody (2.6 BU) of unspecified Ig type. Since diagnosis of the inhibitor, he has received 100 RCo U/kg daily for prophylaxis and immune tolerance. He is now bleed-free; however, monthly inhibitor testing shows that his inhibitor persists. Given the limited experience and literature on inhibitors in VWD, the prognosis for such cases is unknown.
Haemophilia nursing practice: A global survey of roles and responsibilities
Authors: Khair Kate , Abu-Riash Mahmoud , Acerbi Ana Claudia , Beijlevelt Marlene , Floros Georgina , Li Kuixing , Rakić Ljiljana , Mbele Bongi , Shoemark Robyn , Munn Jim 
Published: August 2018

Abstract
Haemophilia nursing roles continue to develop alongside nursing as a profession. There are now nurses who practice autonomously, much like a medical practitioner, and many who have extended their roles to deliver direct patient care, education and research. There has been little, if any, comparison with haemophilia nurse roles internationally, nor of the impact of these roles on patient reported outcomes. This paper reports the results of an international survey, of 297 haemophilia nurses from 22 countries, describing current day practice and care. Many nurses work above and beyond their funded hours to improve care through research and evidence-based practice. While some are able to attend international meetings to report and discover this evidence, many due to financial constraints, are not. Others reported difficulty with communicating in English, which limited congress attendance. With on-line learning capability, sharing of best practice is now possible, and this approach should be a platform developed in coming years to further enhance haemophilia nursing practice and ultimately patient care.
Evaluation of a pre-filled diluent syringe (MixPro®) among patient/carer users and nurses
Authors: Pollard Debra , Khair Kate , Percier Cléa , Wong Yen , Shoemark Robyn 
Published: August 2018

Abstract
Management of haemophilia involves on-demand or prophylactic intravenous administration of recombinant or plasma-derived replacement clotting factors or bypassing agents. These products are provided as lyophilised powder and diluent, which need to be mixed to produce a solution for infusion. While this process has previously involved multiple time-consuming steps, several reconstitution systems are now available to make mixing easier and more convenient. This study aimed to investigate experience of use and perceptions of the Novo Nordisk MixPro® mixing device among patients and carers using activated recombinant factor VII (rFVIIa) or recombinant factor VIII (rFVIII) with MixPro, and nurse specialists who were either familiar or unfamiliar with MixPro. Nurses were asked to simulate the preparation of an inactive solution using MixPro. Semi-structured interviews were used to gain insight into participants’ opinions of mixing systems in general and their perceptions of MixPro. Likert scales were used to rate the performance of MixPro against predefined characteristics of mixing systems, and the importance of the predefined characteristics to the design of a mixing system. Patients/carers and unfamiliar nurses identified low contamination risk when mixing as the most important characteristic of a mixing system; the most important criterion for familiar nurses was confidence that patients/carers could prepare the system correctly. MixPro was perceived to perform very well overall, particularly in parameters identified as most important. It was described as being user-friendly, simple and quick; its compactness and portability were highlighted as advantages for storage and travel. The main disadvantages reported related to its small components. The majority of nurses said that they were highly likely to recommend MixPro to their patients.
Evaluation of a shortened course of tranexamic acid for patients with inherited bleeding disorders following dental procedures
Authors: Greig Allison 
Published: August 2018

Abstract
People with Inherited Bleeding Disorders (IBD) are often prescribed a course of Tranexamic Acid (TXA) mouthwash for five to seven days following dental procedures to reduce the risk of bleeding. Informal discussions with patients suggested that many do not complete the prescribed course of treatment. A literature review indicated that TXA was prescribed inappropriately for procedures with a low bleeding risk, and that there are inconsistencies in the recommended dose, mode of administration and duration of TXA for this patient group. A new protocol was implemented in the haemophilia centre at St George’s University Hospital NHS Foundation Trust, London, to rationalise the prescribing of TXA in dental procedures. A study was conducted to explore patients’ experience of this new guideline in the form of a service evaluation. Structured telephone interviews were completed following 39 dental procedures to collect data on concerns about bleeding; whether TXA was taken as prescribed and reasons for non-adherence; and any unplanned post-operative treatment. The financial impact of the new guideline was also explored. Patients were supportive of the new regimen, although almost half (46%) did not complete the prescribed course of TXA. The majority (37/39) were prescribed tablets rather than mouthwash. No patients required additional unplanned haemostasis support to control haemorrhage. Cost savings were made by replacing a five- to seven-day course of TXA mouthwash with a three-day course of TXA tablets. Although the data collected from patient interviews supports the new guideline, patients appear to be making decisions about taking TXA based on their own experience rather than following the prescribed regimen. Prescribers should support patients to make informed decisions about their medicines and incorporate patient experience into individualised regimens. Given the lack of bleeding complications experienced in this cohort of patients, it is possible that TXA is being overprescribed. Further work exploring how patients with IBDs make decisions about taking medicines is needed.
Subcutaneous injection: learning from experience in other specialties
Authors: Pollard Debra , Chaplin Steve 
Published: August 2018

Abstract
Haemophilia treatment is characterised by intravenous infusions of clotting factor concentrates, with nurses frequently taking the lead role in administration, patient training and patient care. In recent years, a number of novel factor and non-factor-based therapies delivered by subcutaneous injection have been developed. These therapies are now undergoing clinical trials and will shortly be available in clinical practice. The coming era of at least some haemophilia treatments being delivered by subcutaneous injection clearly represents a significant change not only for patients (for whom they may be more convenient) but also for haemophilia nurse practice, particularly with respect to bleed and surgical management plans, and hence for nurse training and education. This review describes evidence-based guidance on subcutaneous injection technique and summarises the implications for nurses.
A 3D Broadband Seismometer Array Experiment at the Homestake Mine
Authors: Mandic Vuk , Tsai Victor C. , Pavlis Gary L. , Prestegard Tanner , Bowden Daniel C. , Meyers Patrick , Caton Ross 
Published: August 2018

ABSTRACTSeismometer deployments are often confined to near the Earth’s surface for practical reasons, despite the clear advantages of deeper seismometer installations related to lower noise levels and more homogeneous conditions. Here, we describe a 3D broadband seismometer array deployed at the inactive Homestake Mine in South Dakota, which takes advantage of infrastructure originally setup for mining and is now used for a range of scientific experiments. The array consists of 24 stations, of which 15 were underground, with depths ranging from 300 ft (91 m) to 4850 ft (1478 m), and with a 3D aperture of ∼1.5  km in each direction, thus spanning a 3D volume of about 3.4  km3. We describe unique research opportunities and challenges related to the 3D geometry, including the generally low ambient noise levels, the strong coherency between observed event waveforms across the array, and the technical challenges of running the network. This article summarizes preliminary results obtained using data acquired by the Homestake array, illustrating the range of possible studies supported by the data.
Linguagem e afasia: uma abordagem discursiva da neurolingüística
Authors: Coudry Maria Irma Hadler 
Published: August 2018

Para responder ao convite da Profa. Eni Orlandi - e fazer parte do número temático dos Cadernos destinado à história das idéias lingüísticas, em domínios de estudo da linguagem que compõem uma área de investigação - apresento alguns caminhos tomados por uma Neurolingüística que têm sua origem traçada por condições históricas, início dos anos oitenta, em nosso Departamento, tempo caracterizado por debates fundantes, nele, de idéias e ideais da Lingüística, em várias de suas dimensões, que abriam novas possibilidades de interfaces - envolvendo uso, funcionamento e conhecimento da linguagem e de sistemas de línguas naturais.
Drug Use is Associated with Anti-CD4 IgG-mediated CD4+ T Cell Death and Poor CD4+ T Cell Recovery in Viral-suppressive HIV-infected Individuals Under Antiretroviral Therapy
Authors: Jiang Wei , Luo Zhenwu , Martin Lisa , Wan Zhuang , Fu Pingfu , Wagner Amanda , Ling Binhua , Heath Sonya L. , Haque Azizul , McRae-Clark Aimee 
Published: August 2018

Background:
The role and mechanism of drug use or abuse in Antiretroviral Therapy
(ART)-treated HIV disease are not completely known.

Methods:
To investigate the impact of drug use on HIV pathogenesis without confounding by HIV
replication and ART adherence, we first analyzed the data from our clinical database in 103 HIV+
subjects with viral-suppressed ART treatment by a multiple regression test.

Results:
We found that HIV+ drug users had lower CD4+ T cell counts but higher CD8+ T cell
counts compared to HIV+ non-drug users, and both drug use and nadir CD4+ T cell counts was independently
associated with CD4+ T cell recovery after controlling for sex and age. Next, we enrolled
individuals from four study groups, HIV-negative and HIV+ subjects without any substance
use, HIV-negative and HIV+ subjects with current illicit drug use (either non-injection cocaine or
cannabis). All HIV+ subjects were viral-suppressed with ART treatment (≥ 2 years). Notably, HIV+
drug users had increased plasma anti-CD4 IgG levels compared to the other three study groups
which were inversely correlated with decreased CD4+ T cell counts only in HIV+ drug users. There
was a significant increase in CD4+ T cell recovery following ART in HIV+ non-drug users but not
in HIV+ drug users. Anti-CD4 IgGs purified from plasma of HIV+ drug users induced CD4+ T cell
death in vitro through Antibody-Dependent Cytotoxicity (ADCC).

Conclusion:

These results suggest that drug use prevents immune reconstitution in HIV-infected
individuals despite long-term ART treatment and viral suppression.
ENSINAR E APRENER: DO UNIVERSO AO ÚNICO
Authors: Teixeira Cristina Maria D'Avila 
Published: August 2018

Ensinar e aprender, desde os gregos, são uma unidade designada por um único radical:"Mantheno". Assim, constituem-se coo polo indissociáveis d uma única práxis. a práxis pedagógica.Não há, pois, dicotomia possível entre o ato de ensinar e aprender. O ensino participa da natureza do fenomen educativo, embora a educação não se reduza a esse aspecto. o seu objetivo consiste na "identificação dos elementos culturais que precisam ser assimilados pelos individuos da especie humana para que eles se tornem humanos e, de outro lado e concomitantemente, à descoberta das formas mas adequadas para atingir esse objetivo".
FORMAÇÃO DE PROFESSORES EM EJA:UMA EXPERIÊNCIA PIONEIRA NA BAHIA
Authors: Dantas Tânia Regina 
Published: August 2018

Trata-se de um trabalho de pesquisa em que se destaca a especificidade da educação de jovens e adultos, se analisa a formação docente com base em diversos autores, apoiada em uma literatura atual e pertinente acerca da temática estudada, se justifica a criação de um curso de especiali-zação em EJA no âmbito de uma Universidade Estadual. Objetivando discutir a formação docente, o papel do profes-sor e a especificidade da EJA, apresentam-se algumas reflexões sobre o percurso formativo, críticas e sugestões para a melhoria da qualidade do ensino e da formação dos educadores. Utiliza-se de uma metodologia que privilegia a indução, em uma abordagem qualitativa, realizando uma análise retrospectiva sobre os avanços e os recuos da pro-posta educacional. Como ponto culminante, à guisa de conclusão, reforça a importância da qualificação do educador propondo cursos em nível de pós-graduação, ações afirma-tivas e a revisão das políticas públicas no campo da EJA.
DESAFIOS PARA A INOVAÇÃO PEDAGÓGICA NA UNIVERSIDADE DO SÉCULO 21
Authors: Leite Denise 
Published: August 2018

As inovações que se desenvolvem nas universidades contem-porâneas refletem exigências das agências de avaliação ou de fomento à pesquisa, ou ainda demandas do setor produ-tivo. De certa forma, tais inovações têm caráter de inovação tecnológica e se destinam a ampliar as alternativas de inserção nos mercados globais. A inovação tecnológica tem relevância para os países integrados ao mundo competitivo. O desafio da universidade, no entanto, está em colocar ao lado da inovação tecnológica, a inovação pedagógica. Neste artigo, discuto o tema com apoio em pesquisas recentes.Entendo que a inovação pedagógica responde ao compro-misso social de formação do humano docente e do humano aluno. Ela se afirma em uma universidade socialmenteempreendedora, uma universidade que forma para a cidadania democrática nos contextos contemporâneos, em suas contradições e paradoxos.