bluuebunny/crossref_metadata_2025_split huggingface dataset:
History of early life adversity is associated with increased food addiction and sex‐specific alterations in reward network connectivity in obesity
Authors: Osadchiy V. , Mayer E. A. , Bhatt R. , Labus J. S. , Gao L. , Kilpatrick L. A. , Liu C. , Tillisch K. , Naliboff B. , Chang L. , Gupta A. 
Published: July 2019

SummaryBackgroundNeuroimaging studies have identified obesity‐related differences in the brain's resting state activity. An imbalance between homeostatic and reward aspects of ingestive behaviour may contribute to obesity and food addiction. The interactions between early life adversity (ELA), the reward network and food addiction were investigated to identify obesity and sex‐related differences, which may drive obesity and food addiction.MethodsFunctional resting state magnetic resonance imaging was acquired in 186 participants (high body mass index [BMI]: ≥25: 53 women and 54 men; normal BMI: 18.50–24.99: 49 women and 30 men). Participants completed questionnaires to assess ELA (Early Traumatic Inventory) and food addiction (Yale Food Addiction Scale). A tripartite network analysis based on graph theory was used to investigate the interaction between ELA, brain connectivity and food addiction. Interactions were determined by computing Spearman rank correlations, thresholded at q < 0.05 corrected for multiple comparisons.ResultsParticipants with high BMI demonstrate an association between ELA and food addiction, with reward regions playing a role in this interaction. Among women with high BMI, increased ELA was associated with increased centrality of reward and emotion regulation regions. Men with high BMI showed associations between ELA and food addiction with somatosensory regions playing a role in this interaction.ConclusionsThe findings suggest that ELA may alter brain networks, leading to increased vulnerability for food addiction and obesity later in life. These alterations are sex specific and involve brain regions influenced by dopaminergic or serotonergic signalling.
Congenital spindle cell rhabdomyosarcoma
Authors: Whittle Sarah B. , Hicks M. John , Roy Angshumoy , Vasudevan Sanjeev A. , Reddy Kiranmye , Venkatramani Rajkumar 
Published: July 2019

AbstractSpindle cell and sclerosing rhabdomyosarcoma (ssRMS) is a rare variant of rhabdomyosarcoma, which includes three distinct subtypes. In infants, these tumors are commonly associated with recurring fusions involving VGLL2 or NCOA2 and have a favorable prognosis. We present four cases of ssRMS and 16 additional cases from the literature, which show that these patients present with localized disease and have an excellent prognosis regardless of surgical margin or lack of radiation therapy. Molecularly defined spindle cell rhabdomyosarcoma in infants is likely a biologically distinct entity which may not require the aggressive multimodal treatment used for other subtypes of rhabdomyosarcoma.
Synergistic effect of surface modification of carbon fabrics and multiwall carbon nanotube incorporation for improving tribological properties of carbon fabrics/resin composites
Authors: Wang Beibei , Fu Qiangang , Li Hejun , Qi Lehua , Lu Yuanyuan 
Published: July 2019

AbstractSurface modification of carbon fabrics (CFs) by nitric acid and multiwall carbon nanotube (MWCNT) incorporation into the resin matrix were simultaneously applied for CFs/resin composites to improve their tribological properties. The results show that surface roughness (Ra) of CFs increases from 8.20 to 15.10 nm after nitric acid treatment due to the remove of sizing agent on CFs surface. Surface hardness of the composites with 0.1 wt% MWCNT (CFR‐H‐0.1%T) is enhanced from 0.745 to 1.216 GPa compared with that of untreated CFs/phenolic resin composites (CFR), which is attributed to the toughening effect of MWCNT in resin matrix. The friction coefficient increases from 0.10 for CFR to 0.16 for CFR‐H‐0.1%T, while the wear rate significantly decreases from 5.75 × 10−14 m3 (N m)−1 to 2.05 × 10−14 m3 (N m)−1. The improvement of friction and wear properties is ascribed to the synergistic effect of the oxidation etching of nitric acid and the strengthening and toughening of MWCNT.
Adherence to ESC guideline‐recommended medications over a 36‐month follow‐up period after hospitalization for heart failure: Results from the EPICAL2 cohort study
Authors: Bitar Sarah , Agrinier Nelly , Alla François , Rossignol Patrick , Mebazaa Alexandre , Thilly Nathalie 
Published: July 2019

AbstractPurposeThe purpose of the study is to describe the trajectories of oral medication prescriptions in patients with heart failure with reduced ejection fraction (HFrEF) over 3 years after discharge from hospitalization for heart failure. We then evaluated the adherence of these prescriptions to the European Society of Cardiology (ESC) guideline‐recommended medications and identified patient characteristics associated with nonadherence.MethodsWe used data from the EPICAL2 cohort study. HFrEF patients who had completed prescriptions at discharge and at 6‐month follow‐up were included and followed for 36 months. The following medication agents were considered adherent to guidelines: renin‐angiotensin system (RAS) blockers [angiotensin‐converting enzyme inhibitor (ACEI) or an angiotensin‐receptor blocker (ARB)] plus a β‐blocker (BB) or RAS blocker plus BB plus mineralocorticoid receptor antagonists (MRAs). The evolution of drug prescriptions and the adherence to ESC guidelines were assessed by using sequence analysis and clustering approaches. Patient characteristics associated with nonadherence were identified by logistic regression analyses.ResultsA typology of four therapeutic clusters was obtained, among which two clusters were adherent to recommendations and two were not. The adherent clusters consisted of bitherapy (RAS blockers‐BB) and tritherapy (RAS blockers‐BB‐MRA) for about 64% of patients and remain stable over time. The nonadherent clusters consisted of nonprescription of BB for about 22% of patients or nonprescription of RAS blocker for about 14%. The main reason for nonprescription of BB was a concomitant obstructive airway disease (asthma or COPD) but was a concomitant chronic kidney disease for nonprescription of RAS blocker.ConclusionAdherence to guideline‐recommended medications while being hospitalized is of great importance because prescriptions are quite stable over time after discharge. HFrEF patients are most often older, with various comorbidities, such as chronic kidney disease or asthma/COPD, which importantly limit physicians' ability to prescribe recommended drugs, leading to suboptimal adherence to guidelines.
High‐resolution computed tomography features of lung disease in perinatally HIV‐infected adolescents on combined antiretroviral therapy
Authors: du Plessis Anne‐Marie , Andronikou Savvas , Machemedze Takwanisa , Griffith‐Richards Stephanie , Myer Landon , Mahtab Sana , Zar Heather J. 
Published: July 2019

AbstractIntroductionChronic lung disease is common in perinatally HIV‐infected children as they increasingly surviving into adolescence. There are few data on the radiologic spectrum of disease in this population.MethodsContrasted high‐resolution computed tomography (HRCT) was performed in ambulatory South African adolescents enrolled in a prospective study of perinatally‐infected adolescents aged 9 to 14 years established on combined antiretroviral therapy (cART) and followed for 36 months. Consecutive participants with reduced lung function (defined by a forced expiratory volume in 1 second [FEV1] of <80% normal and/or lung diffusion capacity [DLCO] <80% normal] underwent HRCT. History, clinical, and laboratory data were collected. Two radiologists blinded to clinical data and to each other, reported scans using standardized methodology; a third radiologist resolved discrepancies.ResultsAmongst 100 participants undergoing HRCT, median age was 13.8 years (12.8‐15.1). The median duration on cART was 8.4 years (IQR = 5.7‐9.8). Mosaic attenuation was the most common finding (73%). Of these 71 (91%) demonstrated associated air trapping radiologically consistent with bronchiolitis obliterans. Bronchiectasis occurred in 39% with significant correlation between extent of bronchiectasis and mosaic attenuation (r = 0.57, P < .001). Prior hospitaliszation for childhood pneumonia at any time before enrollment was associated with mosaic attenuation (OR = 3.9, 95%CI, [1.2‐12.5]); prior pulmonary tuberculosis (TB) was associated with the combination of mosaic attenuation and bronchiectasis (OR = 4.9, 95%CI, [1.6‐15.7]). Most participants (86%) with mosaic attenuation had stage III or IV HIV disease at time of HIV diagnosis (OR = 3.6; [0.9‐14.9]). Inter observer agreement between the two readers was good for bronchiectasis (K = 0.71) and moderate for mosaic attenuation (K = 0.51).DiscussionDespite well‐controlled HIV and long duration of cART, HRCT changes were common in perinatally HIV‐infected adolescents. There was a high prevalence of small airways disease with and without associated bronchiectasis. These changes were associated with prior pulmonary TB or prior severe pneumonia. Strategies to prevent and treat early life respiratory infection must be strengthened to reduce the burden of chronic lung disease in HIV‐infected adolescents.
Misidentification error associated with classifications of white‐tailed deer images
Authors: Newbolt Chad H. , Ditchkoff Stephen S. 
Published: July 2019

ABSTRACTCamera traps are widely used to monitor wildlife, with important management decisions often relying on interpretation of these data. Animal misidentifications are known to be an important source of error in wildlife surveys that require the identification of unique individuals from camera‐trap data; however, the practice of broadly classifying animal images according to sex or age has received less critical attention despite the significant potential for misidentification error under certain circumstances. From 19 January to 1 April 2017, we solicited a group of 726 participants, consisting of both wildlife professionals and nonprofessionals from across the United States, to take an online survey that tested their ability to classify images of known white‐tailed deer (Odocoileus virginianus) according to sex and age. Our goal was to determine the relative influence of tested observer (i.e., experience and familiarity with classifying deer images) and image‐based factors (i.e., distance of deer from camera, day vs. night image) on accuracy of deer classifications. Our results indicated that respondents that were wildlife biologists and those with greater levels of experience viewing deer images were more accurate than others when classifying posthunting season images of deer as adult male, adult female, or fawn. However, the sex–age group of the deer was the most influential predictor of classification reliability, with branched‐antlered adult males being classified more accurately by all respondent groups than were adult females and fawns. Our findings emphasized that animal misidentifications may be an important source of survey error not only when identifying unique individuals, but also under any circumstance where comparative groups lack definitive traits. We suggest that those using camera traps to evaluate wildlife populations should select survey periods that maximize differences among classification groups, when possible, and develop species‐specific image training for observers to improve the reliability of results. Further, population demographics should be considered when evaluating the overall reliability of survey results for species where classification accuracy varies among sex–age groups. © 2019 The Wildlife Society.
Adherence to a food group-based dietary guideline and incidence of prediabetes and type 2 diabetes
Authors: den Braver Nicolette R. , Rutters Femke , van der Spek Andrea L. J. Kortlever , Ibi Dorina , Looman Moniek , Geelen Anouk , Elders Petra , van der Heijden Amber A. , Brug Johannes , Lakerveld Jeroen , Soedamah-Muthu Sabita S. , Beulens Joline W. J. 
Published: July 2019

Abstract
Purpose
In this study, we investigated the association between adherence to the Dutch Healthy Diet index 2015 (DHD15-index) and incidence of prediabetes (preT2D) and Type 2 Diabetes (T2D) in a representative sample for the general Dutch population.

Methods
Two prospective cohort studies, The Hoorn and The New Hoorn Study, were used for data analyses. In total, data from 2951 participants without diabetes at baseline (mean age 56.5 ± 7.5 years; 49.6% male) were harmonized. Baseline dietary intake was assessed with validated Food Frequency Questionnaires and adherence to the DHD15-index was calculated (range 0–130). PreT2D and T2D were classified according to the WHO criteria 2011. Poisson regression was used to estimate prevalence ratios between participant scores on the DHD15-index and preT2D and T2D, adjusted for follow-up duration, energy intake, socio-demographic, and lifestyle factors. Change in fasting plasma glucose levels (mmol/L) over follow-up was analysed using linear regression analyses, additionally adjusted for baseline value.

Results
During a mean follow-up of 6.3 ± 0.7 years, 837 participants developed preT2D and 321 participants developed T2D. The highest adherence to the DHD15-index was significantly associated with lower T2D incidence [model 3, PRT3vsT1: 0.70 (0.53; 0.92), ptrend = 0.01]. The highest adherence to the DHD15-index pointed towards a lower incidence of preT2D [PRT3vsT1: 0.87 (0.74; 1.03), ptrend = 0.11]. Higher adherence to the DHD15-index was not associated with change in fasting plasma glucose levels [β10point: − 0.012 (− 0.034; 0.009)mmol/L].

Conclusion
The present study showed that the highest compared to the lowest adherence to the DHD15-index was associated with a lower T2D incidence, and pointed towards a lower incidence of preT2D. These results support the benefits of adhering to the guidelines in T2D prevention.
Predicting disease progression in high-grade glioma with neuropsychological parameters: the value of personalized longitudinal assessment
Authors: Butterbrod Elke , Bruijn Jimme , Braaksma Meriam M. , Rutten Geert-Jan M. , Tijssen Cees C. , Hanse Monique C. J. , Sitskoorn Margriet M. , Gehring Karin 
Published: July 2019

Abstract
Purpose
Progressive disease in patients with high-grade glioma may be reflected in cognitive decline. However, the cognitive functions most sensitive to progression may differ between patients. We investigated whether decline on a personalized selection of tests predicted progressive disease according to RANO criteria in high-grade glioma patients.

Methods
Starting one day before surgery, patients underwent neuropsychological assessment every three months during standard treatment and clinical follow-up. We first made a personalized selection of three tests that showed the highest Reliable Change Index (RCI) values, i.e., most positive change, at the first post-surgical assessment for each patient. In subsequent follow up, a decline of RCI ≤ − 1 on at least two of the three tests in the selection was considered cognitive decline. We performed a discrete Cox proportional hazards model including a time-dependent coefficient cognitive decline (vs. stability) and covariate age to predict progressive disease.

Results
Twenty five patients were included. Cognitive decline on the personalized test selection preceded or had occurred by the time progression was established in 9/15 patients with RANO confirmed progressive disease (60%). Decline was absent in 8/10 patients (80%) with stable disease during participation. The independent hazard ratio for progression in case of cognitive decline was 5.05 (p < 0.01) compared to stable performance.

Conclusions
Using only three patient-specific neuropsychological tests, we found a fivefold increased chance of disease progression in case of cognitive decline as compared to stable performance. Brief, patient-tailored cognitive assessment may be a noninvasive addition to disease monitoring without overburdening patients and clinical care.
Exploiting data in smart factories: real-time state estimation and model improvement in metal forming mass production
Authors: Havinga Jos , Mandal Pranab K. , van den Boogaard Ton 
Published: July 2019

Abstract
Modern production systems have numerous sensors that produce large amounts of data. This data can be exploited in many ways, from providing insight into the manufacturing process to facilitating automated decision making. These opportunities are still underexploited in the metal forming industry, due to the complexity of these processes. In this work, a probabilistic framework is proposed for simultaneous model improvement and state estimation in metal forming mass production. Recursive Bayesian estimation is used to simultaneously track the evolution of process state and to estimate the deviation between the physics-based model and the real process. A sheet bending mass production process is used to test the proposed framework. A metamodel of the process is built using proper orthogonal decomposition and radial basis function interpolation. The model is extended with a deviation model in order to account for the difference between model and real process. Particle filtering is used to track the state evolution and to estimate the deviation model parameters simultaneously. The approach is tested and analysed using a large number of simulations, based on pseudo-data obtained from a numerical sheet bending model.
Estimation of daily selenium intake by 3- to 5-year-old Japanese children based on selenium excretion in 24-h urine samples
Authors: Nakamura Yoshitaka , Fukushima Michiko , Hoshi Seiko , Chatt Amares , Sakata Takashi 
Published: July 2019

AbstractTo evaluate the daily Se intake of 3- to 5-year-old Japanese children, we used seventy-two urine samples collected from fifty-three children (twenty-seven male and twenty-six female) from two cities in Miyagi prefecture, Japan. For measuring low Se concentrations with high precision, accuracy and rapidity in the 24-h urine samples, we developed an instrumental neutron activation analysis (INAA) method, that is without any chemical separation, using the short-lived77mSe (t1/2= 17·4 s) nuclide. The estimated Se intake of the fifty-three children was 51·5 (sd30·2) µg/d (geometric mean: 42·7 µg/d). Ten subjects (three male and seven female), successfully provided 24-h urine samples over two or three consecutive days; their Se intake was 37·4 (sd5·9) µg/d. Based on the logarithmically transformed data of these ten subjects, the ratio of intra-/inter-individual variances of usual Se intake was 16·7 (28·0/1·7) and geometric mean was 27·7 µg/d. The 5th to 95th percentile of usual Se intake of these ten subjects was 17·5 to 40·4 µg/d, which ranged between the recommended dietary allowance and tolerable upper intake level of Se by the Dietary Reference Intakes for Japanese (2015).
The Difference Denominations Made: Identifying the Black Church(es) and Black Religious Choices of the Early Republic
Authors: Bulthuis Kyle T. 
Published: July 2019

ABSTRACTScholars of African-American religious history have recently debated the significance of the black church in American history. Those that have, pro and con, have often considered the black church as a singular entity, despite the fact that African Americans affiliated with a number of different religious traditions under the umbrella of the black church. This article posits that it is useful to consider denominational and theological developments within different African-American churches. Doing so acknowledges plural creations and developments of black churches, rather than a singular black church, which better accounts for the historical experience of black religion. In this piece, I analyze four different denominational and theological traditions that blacks followed in the early Republic: the Anglican–Episcopalian, the Calvinist (Congregational–Presbyterian), the Methodist, and the Baptist. Each offered a unique ecclesiastical structure and set of theological assumptions within which black clergy and laity operated. Each required different levels of interaction with white coreligionists, and, although some tended to offer more direct opportunities for reform and resistance, all groups suffered differing constraints that limited such action. I argue that the two bodies connected to formalist traditions, the Episcopalian and Calvinist, were initially better developed despite their smaller size, and thus disproportionately shaped black community and reform efforts in the antebellum United States.
“The world food crisis is not a fad”: TheMore-with-LessCookbook and Protestant Environmental Spirituality
Authors: Rose Kevin Stewart 
Published: July 2019

ABSTRACTThis article examines the spirituality reflected in the 1976 cookbookMore-with-Less. Written by a former Mennonite missionary hoping to provide religious households with a practical way to respond to world hunger, the cookbook's message of a simple diet that could transform users' influence on the world is an early example of the religious environmentalism that has grown increasingly popular among middle-class American Protestants in the last several decades. By examining its historical context, narrating its genesis, and critically assessing the spirituality it recommended, this article argues that the cookbook provides a useful window into Protestant environmental spirituality, its version of which allowed practitioners to maintain traditional institutional relationships and conceptions of the divine while cultivating the individuated religiosity increasingly sought after in modern culture. Emerging in the institutional overlap of traditional religious organizations and the putatively secular formations of mass media, globalization, and consumer culture, the cookbook leveraged the incipient emphasis on lifestyle choices within consumer culture to craft an individuated response to a vision of the world in permanent crisis.More-with-Lessand the Protestant environmental spirituality it represents shed light on current scholarly debates about the form religion takes within modern contexts of secularity, especially when religious practitioners seek adaptations that can maintain traditional theological and organizational commitments.
Confessions of a Serial Polygamist: The Reality of Radiocarbon Reproducibility in Archaeological Samples
Authors: Bayliss Alex , Marshall Peter 
Published: July 2019

AbstractSince 1993 Historic England (and its predecessor English Heritage) has commissioned 9074 radiocarbon (14C) measurements on archaeological samples. Over 80% of these have been interpreted within formal Bayesian statistical models. The multiple strands of reinforcing evidence incorporated in these models provide precise chronologies that make stringent demands on the accuracy of the 14C results included in the analysis. Inter-laboratory replication is consequently a routine part of model construction and validation. We report an analysis of replicate measurements on 1089 archaeological samples. It is clear that laboratory reproducibility accounts for only part of the observed variation. The type of material dated is also critical to the reproducibility of measurements, with some sample types proving particularly problematic.