bluuebunny/crossref_metadata_2025_split huggingface dataset:
External quality assessment of p210 BCR‐ABL1 transcript quantification by RT‐qPCR: Findings and recommendations
Authors: Fu Yu , Zhang Rui , Wu Qisheng , Zhang Jiawei , Bao Lihua , Li Jinming 
Published: September 2018

AbstractIntroductionExternal quality assessment (EQA) is an essential tool for quality assurance of analytical testing processes of p210 BCR‐ABL1 transcripts by RT‐qPCR. As an EQA provider, the National Center for Clinical Laboratories organized an EQA scheme of p210 BCR‐ABL1 testing in China for the first time to identify existing problems and ensure the reliability of p210 BCR‐ABL1 testing.MethodsUsing armored RNA technology, we first constructed pACYC‐MS2‐p210 and CG recombinant plasmids and expressed p210 and CG armored RNAs, with packaging segments of p210 BCR‐ABL1 fusion gene (FG) and four common control gene (CG) transcripts. Using these armored RNAs, we prepared lyophilized p210 quality control (QC) sample panels and evaluated detection performance of participating laboratories in China.ResultsOf the 66 participating laboratories, great variation was found with coefficient of variation (CV%) of raw p210 BCR‐ABL1 results basically ranging from 60.0% to 100.0%. In 24 International Scale (IS) laboratories, the CV% of results decreased from 82.4% to 61.6%, and the percentage of laboratories within 2‐, 3‐, and 5‐fold of the median values increased from 78.2%, 87.0%, and 92.1% to 80.1%, 89.4%, and 97.2%, respectively, after conversion with a laboratory‐specific conversion factor (CF); however, poorly converted results were also observed in laboratories resulting from changed components of RT‐qPCR procedures. False‐negative and false‐positive results were also found in the EQA.ConclusionsVarious problems were found for p210 BCR‐ABL1 detection in the EQA. By solving the existing problems, the performance of p210 BCR‐ABL1 detection can be improved, ensuring robust laboratory diagnostic capacities in China.
Credit Cards: Transactional Convenience or Debt‐Trap?
Authors: Brown Stephen , Veld Chris , Veld‐Merkoulova Yulia 
Published: September 2018

AbstractWe survey individuals on their credit card usage. Contrary to popular press, most credit card holders use credit cards in a responsible manner. They tend to use credit cards for transaction convenience and pay little interest. Only a minor subset of people uses credit cards to access expensive credit, with only 7% of credit card holders in our sample never paying the balance in full. Credit card debt is more common among older, less financially literate, and less trusting respondents. Even individuals with credit card debt are well aware about its costs and are likely to make informed financial choices.
Erosion behavior and luminescence properties of Y3Al5O12:Ce3+‐embedded calcium bismuth borate glass‐ceramics for WLEDs
Authors: Xia Libin , Xiao Qinghui , Ye Xinyu , You Weixiong , Liang Tongxiang 
Published: September 2018

AbstractCurrent white light emitting diodes (WLEDs) have poor thermal stability and lack red‐light, which restrict their applications in high‐power and high‐color‐rendering‐index solid‐state lighting. YAG glass‐ceramics provide an efficient way to resolve these problems. Herein, novel YAG‐embedded calcium bismuth borate glass‐ceramics (YAG‐GCs) with Eu3+ doping were prepared using a rapid melt quenching technique. The precursor glass exhibits superior YAG refractive index matching and high transmittance. Differential scanning calorimeter simulations verify YAG particles react with the precursor glass. The degree of YAG erosion is slight but monotonously increases with the co‐sintering temperature from 640 to 700°C. The erosion products probably contain YAB (Al3Y(BO3)4), Al3Eu(BO3)4, Bi24B2O39, and Ca12Al14O33 phases, and the Bi ion valence state is maintained during the reaction process. The energy transfer from Ce3+ to Eu3+ is suppressed. The YAG‐GC PL intensities monotonously increase as the co‐sintering temperature decrease from 640 to 700°C and the YAG content increase from 2.5 to 7 wt.%. The optical parameters of a WLEDs packed by YAG‐GCs and blue chips are a luminous efficiency of 105.3 lm/W, correlated color temperature of 3940 K and color rendering index of 70.1. The as‐prepared YAG‐GCs are promising candidates for high‐power, warm WLEDs due to their superior thermal stability, high quantum efficiency, and low cost.
Exploration of bluish violet‐emitting phosphor Ca3Al4ZnO10:Ti4+ with enhanced emission by Ca2+ vacancies
Authors: Zhou Zhi , Zhong Yuan , Gu Simin , Su Yifeng , Xia Mao , Zhang Yongli , Zhou Nan , Wang Jing 
Published: September 2018

AbstractIn this paper, we introduced a bluish violet‐emitting phosphor Ca3Al4ZnO10:Ti (IV) (CAZO:Ti4+) synthesized by high‐temperature solid‐state reaction. Upon 265 nm excitation, a broad emission band spanned from 300 nm to 500 nm and centered at 370 nm was observed. In addition, the effects of flux and charge compensation to photoluminescence properties of CAZO:Ti4+ were systematically investigated. The results show that 103% improvement of emission intensity was achieved when 1% H3BO3 flux was introduced and 32.8% enhancement of it for 2% Ca2+ vacancies doped as charge compensator. Moreover, the lifetimes, band gap energy, concentration quenching mechanism, as well as electron transition process of CAZO:Ti4+ were discussed. Due to the efficient broad bluish violet emission, this phosphor may find a potential application in mercury vapor‐excited fluorescent lamp for plant growth.
Compositional dependency of Cd‐S‐Se quantum dots within silicate glass on color conversion for a white LED
Authors: Han Karam , Im Won Bin , Heo Jong , Chung Woon Jin 
Published: September 2018

AbstractQuantum dot embedded glasses (QDEGs) were prepared by the conventional melt‐quenching method to enhance its color conversion efficiency via optimizing the concentration of ZnS, ZnSe, and CdO within the silicate‐based glass matrix. The QDEG, which contained 0.875 ZnS, 0.625 ZnSe, and 0.75 CdO (in mol%) and was heat treated at 500°C for 10 hours showed promising color conversion with an improved quantum yield of up to 25%. Color coordination of light‐emitting diodes (LEDs) mounted with the QDEGs could be adjusted by tuning heat‐treatment conditions and thickness control of QDEGs. The practical feasibility of the QDEG for a white LED is demonstrated with a reasonable glass thickness for LED packaging process. The formation of Cd‐S‐Se quantum dots within a glass matrix was identified by Raman and HR‐TEM analyses. The effect of ZnSe and CdO on the formation of Cd‐S‐Se quantum dots within silicate glass is also discussed.
Completely nonfluoroscopic catheter ablation of left atrial arrhythmias and ventricular tachycardia
Authors: Sadek Mouhannad M. , Ramirez F. Daniel , Nery Pablo B. , Golian Mehrdad , Redpath Calum J. , Nair Girish M. , Birnie David H. 
Published: September 2018

AbstractIntroductionFluoroscopy use during catheter ablation procedures increases the cumulative lifetime radiation exposure of patients and operators, potentially leading to a higher risk of cancer and radiation‐related injuries. Nonfluoroscopic ablation (NFA) has been described for supraventricular tachycardia, typical atrial flutter, paroxysmal atrial fibrillation (AF), and outflow‐tract ventricular tachycardia (VT). Complete transition to NFA of more complex arrhythmias, including persistent AF, left atrial (LA) flutter, and structural VT, has not been previously described. We describe the transition to completely NFA of complex arrhythmias, including LA flutter and structural VT. The techniques, challenges, limitations, and results are described.Methods and ResultsComplex ablation procedures were performed using intracardiac echocardiography (ICE) and a three‐dimensional mapping system without fluoroscopy or lead protection. Eighty consecutive patients underwent NFA (mean age, 60.1 ± 9.9 years, 70 with LA arrhythmias, 10 with VT). All cases were performed without the need for rescue fluoroscopy. There was an initial increase in procedural time for ablation of LA arrhythmias upon transitioning to NFA. However, after excluding the first 20 NFA cases to allow for operator learning, the transition to NFA was not associated with an increase in mean procedural time (229 ± 38 vs 225 ± 32 minutes; P = 0.002 for noninferiority). All procedures were completed successfully with no complications.ConclusionsNFA of most complex arrhythmias (persistent AF, LA flutter, and structural VT) is feasible, with a modest learning curve and no increase in procedural times.
Avoiding inappropriate therapy of single‐lead implantable cardioverter‐defibrillator by using atrial‐sensing electrodes
Authors: Kurt Muhammed , Jathanna Nikesh , Babady Mehran , Schmidt Jan , Müller Patrick , Gerguri Shqipe , Clasen Lukas , Bejinariu Alexandru , Kelm Malte , Fürnkranz Alexander , Makimoto Hisaki 
Published: September 2018

AbstractIntroductionThe single‐chamber implantable cardioverter‐defibrillator (ICD) can be associated with more frequent inappropriate therapies compared with dual‐chamber ICDs, when they are accompanied by a simpler implantation procedure. The aim of this study was to investigate whether the use of a single‐lead ICD system with atrial‐sensing electrodes results in a reduction of inappropriate ICD therapy.Methods and ResultsThe study population consisted of 212 consecutive patients, who underwent primary prophylactic single‐lead ICD implantation at our institute. A ventricular lead with atrial‐sensing electrodes was implanted in 77 patients (36%; Group‐VDD) and a ventricular lead without atrial‐sensing electrodes was implanted in 135 patients (64%; Group‐VVI). Procedural and follow‐up data were collected in a prospective registry. A higher prevalence of atrial fibrillation was present in Group‐VDD. There were no other significant differences in patient baseline characteristics (age, sex, and other comorbidities) or follow‐up period between the two groups. The operative parameters including fluoroscopic burden showed no significant differences between Group‐VDD and Group‐VVI. During a mean follow‐up period of 697 ± 392 days, 26 patients (12%) experienced appropriate ICD therapies and 13 patients (6%) suffered inappropriate ICD therapies. The incidence of inappropriate ICD therapies in Group‐VDD was significantly lower as compared to that of Group‐VVI (1/77 [1%] vs 12/135 [9%]; log‐rank,
P = 0.028). The incidence of appropriate ICD therapies and the occurrence of device‐related complications showed no significant difference between the two groups.ConclusionSingle‐lead ICD with atrial‐sensing electrodes shows a lower incidence of inappropriate ICD therapy compared with the absence of atrial‐sensing electrodes, without additional operative burden or increased complications.
Morphological Redescription and Molecular Identification of Trichodina reticulata Hirschmann & Partsch, 1955 (Ciliophora, Mobilida, Trichodinidae) with the Supplemental New Data of SSU rDNA and ITS‐5.8S rDNA
Authors: Wang Shaobin , Zhao Yuanjun , Du Yanhong , Tang Fahui 
Published: September 2018

AbstractDuring a survey of trichodinids in Chongqing, China, two populations of Trichodina reticulata Hirschmann & Partsch, 1955 were isolated from gills of the freshwater fishes, Carassius auratus and Ctenopharyngodon idellus, and 11 molecular samples containing small subunit (SSU) rDNA and internal transcribed spacer (ITS)‐5.8S rDNA were newly sequenced. Both populations fell within the range of morphometry and corresponded well with the diagnostic morphological features of Trichodina reticulata Hirschmann & Partsch, 1955. It should be noted that one population possessed obvious central granules in the adhesive disc, while the other one did not. The detailed morphological redescription for these two populations is given in this work. Although some intraspecific differences were found, both populations were confirmed as Trichodina reticulata based on the morphological study and molecular data, including the sequence analysis of the primary and secondary structures of SSU rDNA, genetic distances and phylogenetic tree. Our study supports the assertion that central granules in the adhesive disc might be an auxiliary feature rather than a heritable character for determining taxonomic affiliations among trichodinids.
Effect of time pressure on the burnout of home‐visiting nurses: The moderating role of relational coordination with nursing managers
Authors: Cao Xiaoyi , Naruse Takashi 
Published: September 2018

AbstractAimTo examine the main effects of time pressure and relational coordination with nursing managers on burnout and to further analyze the moderating role of relational coordination with nursing managers on the association between time pressure and burnout among home‐visiting nurses in Japan.MethodsThis was a cross‐sectional, quantitative study comprising 93 home‐visiting nurses in Japan. A hierarchical moderated regression analysis with mean‐centered predictor variables was used to explore the main effects of time pressure and relational coordination with nursing managers on burnout and the moderating effect of relational coordination with nursing managers on the time pressure and burnout relationship.ResultsTime pressure was a significant positive predictor for emotional exhaustion and depersonalization, respectively. Relational coordination with the nursing managers was significantly and negatively related to depersonalization; however, its main effect on exhaustion was non‐significant. Significant interaction effects of time pressure and relational coordination with the nursing managers on exhaustion and depersonalization also were identified. Time pressure was a significant positive contributor to exhaustion and depersonalization when the home‐visiting nurses reported low relational coordination with the nursing managers.ConclusionRelational coordination with nursing managers is a critical resource for dealing with high time pressure. Strategies, such as establishing a skill‐mix program to alleviate nurses’ time pressure and creating a supportive work environment to facilitate relational coordination with nursing managers, might be effective ways to prevent burnout, as well as management interventions among home‐visiting nurses.
Annual report of the Women's Health Care Committee, Japan Society of Obstetrics and Gynecology, 2018
Authors: Kitawaki Jo , Kato Kiyoko 
Published: September 2018

AbstractSince 2010, the Women's Health Care Committee has addressed important issues linked to women's quality of life. The five agendas this committee has engaged this academic year are: (i) clinical study of urinary complications in perinatal and postpartum women's health care; (ii) education on infectious diseases prophylaxis in obstetrics and gynecology in Japan; (iii) educational activities regarding management guidelines for a female athlete's health care; (iv) training program for women's healthcare advisers; and (v) pregnancy‐ and lactation‐associated osteoporosis (PLOP). The detailed activities of the five subcommittees are described herein. This report is based on the Japanese version of our annual report (Acta Obst Gynaec Jpn 2018; 70: 1538–1546), which publicizes the activities of our committee.
Waveform analysis of the fetal ECG in labor in patients with intrahepatic cholestasis of pregnancy
Authors: Joutsiniemi Titta , Ekblad Ulla , Rosén Karl G. , Timonen Susanna 
Published: September 2018

AbstractAimIntrahepatic cholestasis of pregnancy (ICP) is reported to be associated with an increased risk of sudden fetal death. The possible mechanism is thought to be cardiac arrhythmia. Prolonged QT interval of the electrocardiogram (ECG) is associated with arrhytmogenic events. The aim of the study was to compare the fetal ECG QT interval during labor in pregnancies complicated with ICP to healthy controls.MethodsThe fetal ECG and QT interval was reviewed retrospectively. The intrapartum QT interval was measured in 61 fetuses born to mothers with ICP and in a control group of similar size. The corrected QT interval (QTc) was calculated using Bazett's formula: QT/√RR. The occurrence of ST segment depression was also included in the analysis.ResultsThe groups were similar regarding to maternal age, parity, BMI, gestational age and smoking habits. The rate of labor induction was significantly higher in ICP patients (P < 0.001). The QTc at the beginning and the end of recording was analyzed and there were no significant differences in these values between the ICP patients and healthy controls (P = 0.467). Most ICP patients used ursodeoxycholic acid (UDCA) for mediation. We analyzed separately patients who had elevated liver enzymes before labor. No significant differences in the QTc were noted in these patients either. Nor were there any significant ST depressions in ICP patients.ConclusionsThe etiology of adverse perinatal outcome and even sudden fetal death in ICP is still controversial. No differences in QTc intervals and ST waveforms during labor were found in our study material.
Effects of a School‐Based Pedometer Intervention in Adolescents: 1‐Year Follow‐Up of a Cluster‐Randomized Controlled Trial
Authors: Isensee Barbara , Suchert Vivien , Hansen Julia , Weisser Burkhard , Hanewinkel Reiner 
Published: September 2018

ABSTRACTBACKGROUNDPhysical activity (PA) is one of the most important health behaviors that may be modified by each individual. To foster PA in adolescents, a school‐based intervention was evaluated.METHODSA cluster‐randomized controlled trial with preassessment in 2014 and follow‐up assessment in 2015 included 29 schools with 1020 students (47.6% girls, mean age = 13.69 years). Intervention students received pedometers and monitored their steps for 12 weeks. Classes with the most steps were awarded. Primary outcomes included moderate‐to‐vigorous PA, out‐of‐school sports activities, active transport assessed through questionnaires, as well as cardiorespiratory fitness measured using the 20‐m shuttle‐run test and anthropometric data (weight, height, body fat, and waist circumference) assessed by study staff.RESULTSSignificant interaction terms between group and time were found for all 3 indicators of PA; intervention students showed a higher increase of PA than control students. The same pattern was shown for cardiorespiratory fitness, but the effect missed significance. A more favorable development for the intervention students was shown for body fat and waist‐to‐height ratio, while there was no effect on body mass index percentile.CONCLUSIONSAn easy way to administer school‐based PA program may enhance students' leisure‐time PA even 1 year after the intervention has ended.
The Influence of Active Gaming on Cardiorespiratory Fitness in Black and Hispanic Youth
Authors: Flynn Rachel M. , Staiano Amanda E. , Beyl Robbie , Richert Rebekah A. , Wartella Ellen , Calvert Sandra L. 
Published: September 2018

ABSTRACTBACKGROUNDYouth in the United States have low levels of cardiorespiratory fitness, a risk factor for childhood obesity. Lower levels of physical fitness for black and Hispanic youth contribute to health disparities. In this feasibility study, we examined active video games (AVGs) as a tool to improve fitness and attitudes toward physical activity during early adolescence.METHODA 6‐week AVG program took place in a youth development program in a high‐poverty neighborhood in New York City. Youth aged 10 to 15 years (50% overweight or obese) participated in 2 fitness tests and completed surveys that captured barriers to physical activity pre‐ and postintervention. Each week, participants played Wii Fit games for 30 minutes.RESULTSParticipants improved the number of sit‐ups and step‐ups they completed from pre‐ to postintervention (p < .05). Participants also increased their self‐efficacy, intention to exercise and perceived social support to exercise (p < .05). Youth reported a high level of enjoyment and perceived Wii Fit as ways to increase physical fitness and increase their physical activity.CONCLUSIONAVGs may be a viable alternative exercise program to increase physical activity for black and Hispanic youth living in poverty‐impacted neighborhoods.
The Effects of Asthma and Bullying on Suicidal Behaviors Among US Adolescents
Authors: Muhammad Lutfiyya N. , Korte Jeffrey E. , Bowman Charles M. , De Santis Mark L. , Nietert Paul J. 
Published: September 2018

ABSTRACTBACKGROUNDPositive associations between suicidal behaviors and asthma have been established in previous adolescent studies. Few studies consider social risk factors, such as bullying. This study involved an analysis of suicidal behaviors and asthma, but also includes an assessment of whether these relationships were modified by the co‐occurrence of bullying.METHODSData included 13,154 participants from the 2013 Youth Risk Behavior Survey (YRBS), collected by the US Centers for Disease Control and Prevention. Logistic regression models were constructed and summarized using odds ratios (ORs) and 95% confidence intervals (95% CIs).RESULTSWhen comparing adolescents with asthma who were bullied at school to those who were not bullied at school, the odds of contemplating suicide were increased by nearly 2‐fold (OR = 1.8, 95% CI = 1.5‐2.3), and the odds of creating a suicide plan were 2.3 times higher (OR = 2.3, 95% CI = 1.7‐3.1). The odds of a suicide attempt and incurring an injury from a suicide attempt were also substantially increased. Similarly, increased odds of suicidal behaviors were observed for adolescents with asthma who were bullied electronically.CONCLUSIONHaving asthma and being bullied are both associated with increased odds of suicidal behaviors.
National Analysis of State Health Policies on Students' Right to Self‐Carry and Self‐Administer Asthma Inhalers at School
Authors: Toups Madeleine M. , Press Valerie G. , Volerman Anna 
Published: September 2018

ABSTRACTBACKGROUNDAsthma has no known cure, and though manageable, it disrupts the everyday lives of over 6 million US children. Because children spend more than half of their waking hours in school, students must be able to carry and administer their inhaler at school to manage their asthma.METHODSThis policy paper is a comprehensive review of all 50 states and the District of Columbia's laws and policies for the self‐carry and administration of quick‐relief asthma inhalers among children in prekindergarten through 12th grade.RESULTSAll states permit students to carry and administer their inhalers at school, although each state differs in their development and implementation of policies for asthma self‐management at school. This review examines how states regulate self‐carry policies by looking at policy development, regulated school systems, relevant stakeholders, required medical records, and school liability.CONCLUSIONSEach state's laws have nuances that create gray areas, increasing the potential of misinterpreted or incorrectly implemented policies for asthma self‐management at school. As a result, children may not have immediate access to their inhaler for symptom management or in an emergency. State policymakers should reform current laws to remove barriers for students to carry and use inhalers at school.