bluuebunny/crossref_metadata_2025_split huggingface dataset:
DNA barcoding reveals clear delineation between spawning sites for neritic versus oceanic fishes in the Gulf of Mexico
Authors: Burrows Makenzie , Browning Jeremy S. , Breitbart Mya , Murawski Steven A. , Peebles Ernst B. 
Published: October 2018

AbstractWe combined research‐vessel cruises of opportunity with DNA barcoding to survey planktonic, percomorph fish eggs at 40 stations distributed across and around the Gulf of Mexico (GoM). The objectives were (a) to determine whether eggs of fishes that are potential candidates for the daily egg production method (DEPM) can be readily barcoded, (b) to identify taxa that are spawning in the GoM, (c) to determine encounter rates for eggs of economically valuable taxa, and (d) to characterize individual egg taxa as being primarily neritic, primarily oceanic, or primarily mixed (i.e., both neritic and oceanic). Of the 1,144 eggs that were individually barcoded, 709 (62%) were definitively identified to species (62 species from 42 families), with an additional 20 taxa identified to genus or subfamily level. The eggs of 15 economically important species were identified, most of which had intermediate encounter rates and moderately dispersed spatial distributions, as indicated by an index of aggregation. SIMPROF analysis of stationwise cluster analysis identified eight significant groups within the 35 stations that yielded percomorph eggs; a corresponding specieswise analysis identified six groups of stations as having a neritic egg community and two groups as having an oceanic community, with a community transition located at the shelf break. Although the neritic and oceanic stations did not share important species, it remains possible that coastal pelagic species have mixed neritic–oceanic distributions. Together, these results indicate DEPM fish‐egg surveys based on DNA barcoding are feasible at the large marine ecosystem scale.
No‐touch ablation in hepatocellular carcinoma has the potential to prevent intrasubsegmental recurrence to the same degree as surgical resection
Authors: Kawamura Yusuke , Ikeda Kenji , Shindoh Junichi , Kobayashi Yuta , Kasuya Kayoko , Fujiyama Shunichiro , Hosaka Tetsuya , Kobayashi Masahiro , Saitoh Satoshi , Sezaki Hitomi , Akuta Norio , Suzuki Fumitaka , Suzuki Yoshiyuki , Arase Yasuji , Hashimoto Masaji , Kumada Hiromitsu 
Published: October 2018

AimThe aim of this study was to clarify the utility of a no‐touch pincer ablation procedure that uses bipolar electrodes to prevent intrasubsegmental tumor recurrence after radiofrequency ablation (RFA) for patients with hepatocellular carcinoma (HCC) compared to surgical resection.MethodsWe evaluated 175 consecutive patients with HCC (single nodule, tumor diameter ≤ 30 mm) who underwent surgical resection (146 received partial resection) and 313 patients who received RFA; 277 patients received touch ablation using a monopolar or bipolar RFA device, and 36 received no‐touch ablation using a bipolar RFA device. Pretreatment arterial and portal phase dynamic computed tomography (CT) or magnetic resonance imaging (MRI) images were classified into four enhancement patterns: Type 1 and Type 2 are homogeneous enhancement patterns without or with increased arterial blood flow, respectively; Type 3 is a heterogeneous enhancement pattern with a septum‐like structure; and Type 4 is an irregularly shaped ring structure enhancement pattern.ResultsCumulative recurrence rates significantly differed between procedures (surgical resection, 7.5%; no‐touch ablation, 2.9%; and touch ablation, 17.7% at the third year; P = 0.005). Multivariate Cox proportional hazards analysis revealed that enhancement pattern type (Type 3: hazard ratio [HR], 2.95; P = 0.002; and Type 4: HR, 3.88, P = 0.002), treatment procedure (touch ablation: HR, 3.36; P < 0.001), and serum α‐fetoprotein level (≥30 μg/L: HR, 1.87; P = 0.009) were significant predictors of intrasubsegmental recurrence. No significant differences between no‐touch ablation and surgical resection were observed.ConclusionThe no‐touch pincer ablation procedure has the potential to prevent intrasubsegmental recurrence after RFA for patients with HCC to the same degree as partial resection.
High recovery rate of consciousness by high‐volume filtrate hemodiafiltration for fulminant hepatitis
Authors: Fujiwara Keiichi , Abe Ryuzo , Yasui Shin , Yokosuka Osamu , Kato Naoya , Oda Shigeto 
Published: October 2018

AimAn artificial liver support (ALS) system sustaining patients with acute liver failure (ALF) in good condition until recovery of the native liver or performance of liver transplantation (LT), is essential for the improvement of the poor prognosis of ALF despite the lack of survival benefit. We aimed to investigate the efficacy of various ALS systems for fulminant hepatitis (FH) carried out in our liver unit so far, focusing on the restoration of consciousness from hepatic encephalopathy.MethodsOne hundred and ten consecutive adult Japanese patients with FH admitted to Chiba University Hospital (Chiba, Japan) between 1988 and 2016 who received ALS were analyzed.ResultsRecovery rate of consciousness improved with the increased dialysate flow rate and filtrate rate: 37.5% by plasma exchange (PE), 51.9% by PE + continuous hemodiafiltration (CHDF), 57.7% by slow PE (sPE) + high‐flow CHDF (HFCHDF) (QD = 300 mL/min), 88.6% by HFCHDF (QD = 500 mL/min) (+ sPE), and 92.9% by on‐line HDF (OLHDF) (+ sPE). All patients except one, who could not be fully treated because of circulatory failure, recovered consciousness by OLHDF, including those whose liver function were completely abolished. Superiority of HFCHDF (QD = 500 mL/min) and OLHDF was also shown in patients who died without LT or received LT.ConclusionsMore effective ALS should be recognized considering the extremely high recovery rate of consciousness. In particular, OLHDF with predilution reduces the cost of substitution fluid by supplying an unlimited amount of dialysate as substitution fluid prepared using an on‐line system, and simplifies the procedure for the management.
Amounts of malondialdehyde do not accurately represent the real oxidative level of all vegetable oils: a kinetic study of malondialdehyde formation
Authors: Ma Lukai , Liu Guoqin , Liu Xinqi 
Published: October 2018

SummaryMalondialdehyde (MDA), a widely used oxidation indicator for both lipid and edible oil, has been suggested to be genotoxic and cytotoxic, thus attracting increasing attentions about its formation and exposure assessment. In this study, kinetics of MDA formation in vegetable oils and model oils were investigated by high‐performance liquid chromatography. Results showed MDA contents firstly increased rapidly then kept to a plateau over time in both reaction systems at 100, 140 and 180 °C, significant temperature‐dependent of MDA formation was observed. The rate constant and activation energy (Ea) were calculated from the fitted pseudo‐first‐order model and Arrhenius equation. Ea of MDA‐formation was much lower in linseed oil, corn oil and rapeseed oil, indicating the higher degree of unsaturation resulted in the greater susceptibility to MDA formation. Besides, MDA content was inappropriate to assess the oxidation of palm oil and camellia oil possessing high level of saturated and/or monounsaturated fatty acid.
Exploring comorbid depression and physical health trajectories: A case‐based computational modelling approach
Authors: Castellani Brian , Griffiths Frances , Rajaram Rajeev , Gunn Jane 
Published: October 2018

AbstractWhile comorbid depression/physical health is a major clinical concern, the conventional methods of medicine make it difficult to model the complexities of this relationship. Such challenges include cataloguing multiple trends, developing multiple complex aetiological explanations, and modelling the collective large‐scale dynamics of these trends. Using a case‐based complexity approach, this study engaged in a richly described case study to demonstrate the utility of computational modelling for primary care research. N = 259 people were subsampled from theDiamonddatabase, one of the largest primary care depression cohort studies worldwide. A global measure of depressive symptoms (PHQ‐9) and physical health (PCS‐12) were assessed at 3, 6, 9, and 12 months and then annually for a total of 7 years. Eleven trajectories and 2 large‐scale collective dynamics were identified, revealing that while depression is comorbid with poor physical health, chronic illness is often low dynamic and not always linked to depression. Also, some of the cases in the unhealthy and oscillator trends remain ill without much chance of improvement. Finally, childhood abuse, partner violence, and negative life events are greater amongst unhealthy trends. Computational modelling offers a major advance for health researchers to account for the diversity of primary care patients and for developing better prognostic models for team‐based interdisciplinary care.
Experiences of coeliac disease in a changing gluten‐free landscape
Authors: King J. A. , Kaplan G. G. , Godley J. 
Published: October 2018

AbstractBackgroundCoeliac disease is an autoimmune disorder triggered by the ingestion of gluten. In recent years, there has been considerable increase in the availability of gluten‐free products in North America. The present study investigated how the recent proliferation of the gluten‐free industry has affected individuals living with coeliac disease, with a primary focus on their social lives and relationships.MethodsInterpretive phenomenology was utilised for study design and analysis. Semi‐structured interviews were conducted with 17 adults diagnosed with coeliac disease in Calgary, Alberta. Interviews were audio recorded and then transcribed for analysis.ResultsPeople living with coeliac disease experience the growth of the gluten‐free industry as a ‘double‐edged sword’. Although they are grateful for more palatable gluten‐free options, they are increasingly faced with misunderstandings about the severity of coeliac disease as a result of many noncoeliac disease individuals subscribing to the gluten‐free diet. This ‘double‐edged sword’ made certain types of social situations more easily manageable (e.g. more gluten‐free options available at restaurants), whereas others produced distress (e.g. increased risk of inadvertently consuming gluten). Participants also felt they may be perceived or even perceived themselves differently (e.g. felt high maintenance). To help mitigate these social ramifications of following the gluten‐free diet, participants utilised various strategies.ConclusionsThe sole medical recommendation of a gluten‐free diet fails to acknowledge the ongoing difficulties those with coeliac disease can endure in the current gluten‐free landscape. Recommendations beyond the gluten‐free diet are advisable to alleviate many of the indirect burdens revealed in the present study.
Effectiveness of short‐pulse width Nd:YAG in laser hair reduction
Authors: Jane Subodh D. , Mysore Venkataram 
Published: October 2018

SummaryIntroductionLaser hair reduction (LHR) is a safe and effective way of reducing unwanted hairs over body. Long‐pulse Nd:YAG laser has over the years, been proven to be particularly safe and effective in darker skin types. While conventionally, long‐pulse Nd:YAG laser has been used, recently short‐pulse width Nd:YAG laser of 0.6‐1.6 ms which is 10‐50 times less than the standard method (long‐pulse) of Nd:YAG LHR, has become available.ObjectivesTo study the effectiveness of short‐pulse width Nd:YAG laser in LHR in Indian patients.Material and methodsThis was a prospective observational study conducted over a period of 1 year. Fifty female patients with fitzpatrick skin type 3‐5 were included. Patients underwent four sessions of LHR, with an interval of 6 weeks and then follow up was done for 6 months after the last session.ResultsThe mean age of patient was 29.92 years ranging from 17 to 48 years. After finishing four sessions of LHR procedure 58%, 34%, 6%, and 2% of the patients showed excellent, good, moderate, and poor improvement respectively. No complications were seen during the treatment and after follow‐up. Statistical analysis by paired t test showed the results to be statistically significant.ConclusionHair reduction using unique short‐pulse width Nd:YAG laser is easy to use, safe, and effective in Indian skin.
Low‐fluence Q‐switched Nd:YAG laser for the treatment of melasma in Asian patients
Authors: Choi Jae Eun , Lee Dong Won , Seo Soo Hong , Ahn Hyo Hyun , Kye Young Chul 
Published: October 2018

SummaryBackgroundMelasma is a common acquired facial pigmentary disorder that is resistant to various modalities of treatment. Recently, the low‐fluence 1064‐nm Q‐switched neodymium‐doped yttrium aluminum garnet laser (QSNY) has emerged as the new gold standard of melasma treatment in Asia.ObjectiveTo evaluate the efficacy and safety of low‐fluence 1064‐nm QSNY in Asian patients with melasma.MethodsData of patients with melasma treated with low‐fluence QSNY in the department of dermatology at the Korea University Anam Hospital were reviewed retrospectively. A 1064‐nm QSNY with 8 mm spot size and fluence of 1.2‐2.0 J/cm2 at 10 Hz was used. The results were evaluated using the modified Melasma Area and Severity Index (mMASI) score and the physician's global assessment (PGA).ResultsA total of 40 Korean patients with Fitzpatrick skin type III to IV were included. Patients were treated for a median of 10 sessions at a median of 1‐week intervals. The mean mMASI score decreased by 54.23% from a baseline of 3.19 ± 2.64 to 1.46 ± 1.06 after treatment. On PGA, 1 out of 40 patients (2.5%) showed excellent improvement, 14 (35%) good, 15 (37.5%) fair, 6 (15%) poor, and 4 (10%) no improvement. However, two patients showed mottled hypopigmentation and rebound hyperpigmentation.ConclusionLow‐fluence 1064‐nm QSNY appears to be a safe and effective treatment for Asian patients with melasma.
Effect of platelet‐rich plasma on proliferation and migration in human dermal fibroblasts
Authors: Cho Eun Byul , Park Gil Soon , Park Seok Soon , Jang Ye Ji , Kim Kwang Ho , Kim Kwang Joong , Park Eun Joo 
Published: October 2018

SummaryBackgroundPlatelet‐rich plasma (PRP) is a blood fraction that contains high concentrations of several growth factors. PRP has been recently used in skin wound healing and rejuvenation. However, the precise molecular mechanisms underlying PRP‐induced wound healing are unknown.AimsThis study aimed to evaluate the effects of PRP on extracellular matrix remodeling, which requires the activation of dermal fibroblasts.MethodsCell proliferation and migration assay, enzyme‐linked immunosorbent analysis, and Western blotting were performed on PRP‐treated human skin fibroblasts.ResultsPlatelet numbers were enhanced by 4.6‐fold in PRP compared to that in whole blood. PRP stimulated the proliferation and migration of human dermal fibroblasts and increased the expression of human procollagen I alpha 1, elastin, MMP‐1, and MMP‐2 in human dermal fibroblasts. PRP‐treated human dermal fibroblasts also showed a dramatic reduction in the phosphorylation of c‐Jun N‐terminal kinase (JNK), whereas total JNK levels were not significantly reduced.ConclusionsCollectively, PRP induced increased expression of type I collagen, elastin, MMP‐1, and MMP‐2, thereby accelerating wound healing. Our findings reveal basic mechanisms underlying PRP‐mediated tissue remodeling. Thus, these results could be exploited for clinical dermatology and skin rejuvenation.
Accommodating Options
Authors: Lazar Seth 
Published: October 2018

AbstractMany of us think we have agent‐centred options to act suboptimally. Some of these involve favouring our own interests. Others involve sacrificing them. In this paper, I explore three different ways to accommodate agent‐centred options in a criterion of objective permissibility. I argue against satisficing and rational pluralism and in favour of a principle built around sensitivity to personal cost.
Novel technique for pediatric living donor liver transplantation in patients with portal vein obstruction: The “pullout technique”
Authors: Kasahara Mureo , Sasaki Kengo , Uchida Hajime , Hirata Yoshihiro , Takeda Masahiro , Fukuda Akinari , Sakamoto Seisuke 
Published: October 2018

AbstractPV hypoplasia may increase the risk of posttransplant complications, especially when it extends to near the SMV and SpV junction. We described our experience of 10 pediatric cases of PV hypoplasia/thrombus in which the pullout technique was required for PV reconstruction. There were five male and five female patients. The median age was 9 months, and the median weight was 8.1 kg. The indications for the pullout technique were PV hypoplasia in seven patients and PV thrombus in 3. The inflow sites of the enlarged LGV were as follows: the main PV trunk (n = 2), the SMV and SpV junction (n = 4), and the SpV (n = 4). The posterior face of the pancreas was tunneled along the PV, and the PV was returned to its original position with or without the use of an interposed vein graft. The pullout technique created a good operative field, which allowed for the complete removal of the hypoplastic PV or thrombectomy with the safe use of various interposed vein grafts.
Wicksellian Rules and the Taylor Principle: Some Practical Implications*
Authors: Bauducco Sofia , Caputo Rodrigo 
Published: October 2018

AbstractIn this paper, we derive and compare the determinacy regions of price‐level targeting rules (Wicksellian rules) and Taylor rules in a standard New Keynesian model. We conclude that Wicksellian rules do not require the Taylor principle to hold in order to induce determinacy. Our results have two implications. First, in a univariate setting, the estimation of simple Taylor rules when the true rule is Wicksellian can lead to the erroneous conclusion that the equilibrium is indeterminate. Second, indeterminacy is ruled out when using system‐based methods, but it can be concluded that the central bank is less averse to inflation movements than it actually is.
Effects of high‐intensity functional circuit training on motor function and sport motivation in healthy, inactive adults
Authors: Wilke Jan , Kaiser Stefanie , Niederer Daniel , Kalo Kristin , Engeroff Tobias , Morath Christian , Vogt Lutz , Banzer Winfried 
Published: October 2018

PurposeA small share of the world's population meets current physical activity guidelines, which recommend regular engagement in endurance, strength, and neuromotor exercise. As lack of time represents a major cause of inactivity, multidimensional training methods with short durations may provide a promising alternative to classical, volume‐oriented approaches focusing on one biomotor ability. This trial examined the effects of a high‐intensity functional circuit training (HIFCT) on motor performance and exercise motivation in untrained adults.MethodsThirty‐three inactive participants were randomly allocated to two groups exercising for six weeks. The intervention group (HIFCT, n = 20) 3×/week performed functional whole‐body exercises in a circuit. Each 15‐minute workout included repetitive 20s all‐out bouts with 10s breaks. In the comparison group (moderate aerobic exercise, MAE, n = 13), the participants walked 3×/week for 50 minutes at moderate intensity. Measured motor outcomes were cycling endurance capacity (respiratory threshold, maximum workload), maximum strength (leg and chest press), postural control (force plate), and jump capacity (counter‐movement jump, single leg hop for distance); exercise motivation was assessed using the self‐concordance index.ResultsIn comparison with MAE, HIFCT enhanced maximum leg strength (between‐group difference of relative pre‐ to post‐changes of 5.0%), shoulder strength (7.6%), and endurance workload (5.0%; P < 0.05), while increasing motivation to exercise (+5.5 points, P < 0.05). No between‐group differences occurred for postural control and jump capacity (P > 0.05).ConclusionDespite considerably shorter training duration, HIFCT enhances motor function and motivation to exercise more effectively than MAE. Further research should investigate the long‐term adherence to the program and its effectiveness in other settings.
Bioaugmentation of floating treatment wetlands for the remediation of textile effluent
Authors: Tara Nain , Iqbal Mazhar , Mahmood Khan Qaisar , Afzal Muhammad 
Published: October 2018

AbstractThis pilot study evaluated the effects of bacterial augmentation on the efficiency of floating treatment wetlands (FTWs) to remediate textile wastewater. Two wetland plants, Phragmites australis and Typha domingensis, were used to develop FTWs, which were then augmented with a bacterial consortium of three strains (Acinetobacter junii, Pseudomonas indoloxydans, and Rhodococcus sp.). Results showed that both plant species removed colour, organic matter, toxicity, and heavy metals from textile wastewater and their removal efficiency was further enhanced by augmentation with bacteria. The maximum removal efficiencies of colour, COD and BOD after an 8‐day period were 97, 87 and 92%, respectively, by FTWs carrying P. australis inoculated with the bacterial consortium. Furthermore, the same combination showed 87–99% reduction of heavy metals in the textile wastewater as well. These results indicate that FTWs can be used for the treatment of textile effluent and their working efficiency can be improved by plant‐bacterial synergism.
Occupational therapy interventions in child and adolescent mental health: a mixed methods systematic review protocol
Authors: Brooks Rob , Bannigan Katrina 
Published: October 2018

Review question/objective:
The question of this review is: what is the effectiveness of occupational therapy on participation in everyday occupations for children and adolescents with mental health difficulties? The objective is to identify the evidence of occupational therapy interventions that are occupation-based and/or occupation-focused.
The quantitative component of the review will consider studies that evaluate the effectiveness of occupation-based and/or occupation-focused interventions; the qualitative component of this review will consider studies that investigate the experiences of these interventions, and the textual component of this review will consider publications that describe these occupational therapy interventions.
The quantitative objective is to identify the effectiveness of occupational therapy on participation in everyday occupations for children and adolescents with mental health difficulties.
The qualitative objective is to identify the experiences of occupational therapy interventions on participation for children and adolescents with mental health difficulties in everyday activities.
The textual objective is to identify narrative, text and opinion about occupational therapy interventions on the participation of children and adolescents mental health that have yet to be subjected to empirical analysis.
Experiences of learning, development and preparedness for clinical practice among undergraduate paramedicine students, graduate/intern paramedics and their preceptors: a systematic review protocol
Authors: Hanna Hilding , Jordan Zoe , Peters Micah D.J. 
Published: October 2018

Review question:
What are the barriers and facilitators related to learning, development, and preparedness for practice from the perspective of undergraduate paramedicine students, graduate/intern paramedics and the preceptors/trainers that facilitate learning?
Experiences of women who have planned unassisted home births: a systematic review protocol
Authors: Macdonald Danielle , Etowa Josephine , Helwig Melissa 
Published: October 2018

Review question/objective:
The objective of this review is to identify, appraise and synthesize the qualitative evidence on the experiences of women in high resource countries who have planned unassisted home births. This qualitative review aims to answer the following question: what are the experiences of women who have planned unassisted home births?