bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parent–adolescent communication in a digital world: A 100‐day diary study
Authors: Janssen Loes H. C. , Beyens Ine , Bij de Vaate Nadia A. J. D. , van der Wal Amber , Valkenburg Patti M. , Keijsers Loes 
Published: November 2024

AbstractDigital technology enables parents and adolescents to communicate anywhere and anytime. Knowledge of parent–adolescent online communication, however, is mainly based on cross‐sectional studies. In this preregistered 100‐day diary study, 479 adolescents (Mage = 15.98, 54.9% girls; 96.9% Dutch) reported daily if they had communicated with their parents online, how long (i.e., duration), and what they discussed (i.e., topics). Parent–adolescent online communication took place on 43% of days, for an average of 20 min a day, and predominantly concerned micro‐coordination. Five profiles of parent–adolescent online communication were identified, with most adolescents (55.4%) communicating relatively infrequently and briefly. Boys and younger adolescents communicated longer than girls and older adolescents. Although parent–adolescent online contact is possible all day, very few adolescents do so.
Prospective Clinical Study on the Accuracy of Static Computer‐Assisted Implant Surgery in Patients With Distal Free‐End Implants. Conventional Versus CAD‐CAM Surgical Guides
Authors: Berta García‐Mira , Luigi Canullo , Miguel Peñarrocha‐Diago , Carlos Balaguer‐Martí José 
Published: November 2024

ABSTRACTObjectivesTo compare the accuracy of CAD‐CAM and conventional guides in the static computer‐assisted implant surgery (sCAIS) placement of distal free‐end implants.Material and MethodsA prospective, controlled, and blinded quasi‐experimental study was done involving 27 patients (76 implants) distributed into two groups according to the surgical guide manufacturing approach used: conventional (control group [CG]) or CAD‐CAM (test group [TG]). The implants were planned in the software and the surgical guides were manufactured. Fully guided implant placement was carried out and the deviations were measured along with secondary variables as potential confounding factors. Descriptive analyses were performed on mean, standard deviation (SD), and interquartile range (IQR). In the comparative/inferential analysis hypothesis, contrasts were made of the quantitative and qualitative variables and multiple linear models were generated to adjust for the different confounding variables recorded.ResultsCoronal horizontal deviation (CHD) was significantly greater in CG (1.52 mm) versus TG (1.04 mm) (p = 0.004). Apical horizontal deviation (AHD) in turn was 1.67 versus 1.46 mm, respectively; angular deviation was 2.87 versus 3.64; and vertical deviation was −0.1 versus −0.05 mm, with no significant differences between the groups (p > 0.05). A greater sleeve height, positioning in premolars versus molars, and the use of shorter implants, were associated with greater accuracy in relation to CHD and/or AHD (p < 0.05). The implant success rate at 1 year was 92.1%, 90.7% in TG, and 100% in CG, being statistically significant (p = 0.026) at the implant level, but not significant at the patient level.ConclusionsThe CAD‐CAM surgical guides proved to be more accurate than the conventional guides in the sCAIS placement of distal free‐end implants, with statistically significant differences being observed in terms of CHD. All implant failures occurred in TG (6 implants/3 patients).Trial RegistrationClinicalTrials.gov identifier: NCT06404385
Novel Insights Into the Causal Effects and Shared Genetics Between Body Fat and Parkinson Disease
Authors: Zhao Qian , Liu Dongming , Baranova Ancha , Cao Hongbao , Zhang Fuquan 
Published: November 2024

ABSTRACTAimsExisting observational studies examining the effect of body fat on the risk of Parkinson disease (PD) have yielded inconsistent results. We aimed to investigate this causal relationship at the genetic level.MethodsWe employed two‐sample Mendelian randomization (TSMR) to investigate the causal effects of body fat on PD, with multiple sex‐specific body fat measures being involved. We performed Bayesian colocalization analysis and cross‐trait meta‐analysis to reveal pleiotropic genomic loci shared between body mass index (BMI) and PD. Finally, we used the MAGMA tool to perform tissue enrichment analysis of the genome‐wide association study hits of BMI.ResultsTSMR analysis suggests that except waist circumference, higher measures of body fatness are associated with a decreased risk of PD, including BMI (OR: 0.83), body fat percentage (OR: 0.69), body fat mass (OR: 0.77), and hip circumference (OR: 0.83). The observed effects were slightly more pronounced in females than males. Colocalization analysis highlighted two colocalized regions (chromosome 3p25.3 and chromosome 17p12) shared by BMI and PD and pointed to some genes as possible players, including SRGAP3, MTMR14, and ADORA2B. Cross‐trait meta‐analysis successfully identified 10 novel genomic loci, involving genes of TOX3 and MAP4K4. Tissue enrichment analysis showed that BMI‐associated genetic variants were enriched in multiple brain tissues.ConclusionsWe found that nonabdominal body fatness exerts a robust protective effect against PD. Our colocalization analysis and cross‐trait meta‐analysis identified pleiotropic genetic variation shared between BMI and PD, providing new clues for understanding the association between body fat and PD.
Modified Hank's Balanced Salt Solution as a Storage Medium for Avulsed Teeth: In Vitro Assessment of Periodontal Fibroblast Viability
Authors: Lee Zhi Jin , Ng Sook Luan , Soo Eason , Abdullah Dalia , Yazid Farinawati , Abdul Rahman Mariati , Teh Lay Ann 
Published: November 2024

ABSTRACTBackground/AimThe optimal storage medium for an avulsed tooth should preserve the viability of periodontal fibroblasts (PDLF) to the highest degree, facilitating the re‐attachment of periodontal fibers and improving the prognosis of replantation. This study compared the effect of the PDLF viability in Hank's balanced salt solution (HBSS), supplemented culture medium, that is, Dulbecco's Modified Eagle Medium (DMEM), and four modified HBSS mixtures.Material and MethodsPeriodontal tissues were obtained from extracted human teeth and processed for PDLF culture. The cells were then exposed to six experimental media: (i) HBSS, (ii) HBSS and ascorbic acid (HBSS + Vit C), (iii) HBSS and platelet‐derived growth factor (HBSS + PDGF), (iv) a mixture of HBSS, PDGF, and Vit C (HBSS + PDGF + Vit C), (v) HBSS and platelet lysate (HBSS + PL), and (vi) DMEM for 3, 6, 12, and 24 h. A MTT assay was performed to determine the cell viability.ResultsVitamin C‐containing media maintained PDLF viability significantly better than HBSS + PDGF and HBSS + PL at 3, 6, 12, and 24 h (p < 0.05). The percentages of viable PDLF at 3, 6, 12, and 24 h were significantly higher than 0 h for HBSS + Vit C, HBSS + PDGF + Vit C, HBSS + PL, and DMEM (p < 0.05).ConclusionAll experimental media were able to maintain PDLF viability (DMEM>HBSS+Vit C; HBSS+PDGF+Vit C>HBSS+PL>HBSS+PDGF; HBSS). Although DMEM had the highest cell proliferative effect, it is impractical to be used as a transport medium due to its cost, storage, and availability. The supplementation of Vit C yielded significant cell proliferative effects; hence, HBSS + Vit C can be a better alternative as a storage medium than HBSS.
Management of Complications in Dental Traumatology
Authors: de Gregorio Cesar , Tewari Nitesh 
Published: November 2024

ABSTRACTManagement of traumatic dental injuries is often challenging due to the complexity in diagnosis, concomitant injuries, and the interdisciplinary treatment planning. As a result, the clinicians are often confused and not confident over important treatment decisions. The guidelines of International Association of Dental Traumatology have improved the standard of dental trauma care globally and provide a roadmap for predictable prognosis. However, there are unique situations that require additional investigations such as the Cone Beam Computed Tomography and customized treatment and follow up protocol. An essential requisite for prevention of adverse late complications of dental injuries is clear understanding of their etiopathogenesis and the changes that occur after an injury. Additionally, it is prudent to understand the basic physiology behind the healing that is expected after a treatment protocol. This review presents the science behind the development of late complications of dental injuries and their management protocols in a simplified and clinical manner. An attempt has been made to highlight the clinical paradigms and decisions that reduce the chances of failures in traumatized teeth.
Performance of Artificial Intelligence Chatbots in Responding to Patient Queries Related to Traumatic Dental Injuries: A Comparative Study
Authors: Guven Yeliz , Ozdemir Omer Tarik , Kavan Melis Yazir 
Published: November 2024

ABSTRACTBackground/AimArtificial intelligence (AI) chatbots have become increasingly prevalent in recent years as potential sources of online healthcare information for patients when making medical/dental decisions. This study assessed the readability, quality, and accuracy of responses provided by three AI chatbots to questions related to traumatic dental injuries (TDIs), either retrieved from popular question‐answer sites or manually created based on the hypothetical case scenarios.Materials and MethodsA total of 59 traumatic injury queries were directed at ChatGPT 3.5, ChatGPT 4.0, and Google Gemini. Readability was evaluated using the Flesch Reading Ease (FRE) and Flesch–Kincaid Grade Level (FKGL) scores. To assess response quality and accuracy, the DISCERN tool, Global Quality Score (GQS), and misinformation scores were used. The understandability and actionability of the responses were analyzed using the Patient Education Materials Assessment Tool for Printed Materials (PEMAT‐P) tool. Statistical analysis included Kruskal–Wallis with Dunn's post hoc test for non‐normal variables, and one‐way ANOVA with Tukey's post hoc test for normal variables (p < 0.05).ResultsThe mean FKGL and FRE scores for ChatGPT 3.5, ChatGPT 4.0, and Google Gemini were 11.2 and 49.25, 11.8 and 46.42, and 10.1 and 51.91, respectively, indicating that the responses were difficult to read and required a college‐level reading ability. ChatGPT 3.5 had the lowest DISCERN and PEMAT‐P understandability scores among the chatbots (p < 0.001). ChatGPT 4.0 and Google Gemini were rated higher for quality (GQS score of 5) compared to ChatGPT 3.5 (p < 0.001).ConclusionsIn this study, ChatGPT 3.5, although widely used, provided some misleading and inaccurate responses to questions about TDIs. In contrast, ChatGPT 4.0 and Google Gemini generated more accurate and comprehensive answers, making them more reliable as auxiliary information sources. However, for complex issues like TDIs, no chatbot can replace a dentist for diagnosis, treatment, and follow‐up care.
Effectiveness of sodium channel blockers in treating neonatal seizures due to arterial ischemic stroke
Authors: Pegoraro Veronica , Viellevoye Renaud , Malfilatre Geneviève , Dilena Robertino , Proietti Jacopo , Mauro Isabella , Zardini Cecilia , Dzietko Mark , Lacan Laure , Desnous Beatrice , Cordelli Duccio Maria , Campi Francesca , Da Silva Monica Reis , Fumagalli Monica , Nguyen The Tich Sylvie , Felderhoff‐Müser Ursula , Ventura Giulia , Sartori Stefano , Benders Manon , Pittini Carla , Cavicchiolo Maria Elena , Milh Mathieu , Cantalupo Gaetano , van Maanen Aline , Tataranno Maria Luisa , Cilio Maria Roberta 
Published: November 2024

AbstractObjectiveFew studies have evaluated the efficacy of antiseizure medications (ASMs) according to the etiology of neonatal acute provoked seizures. We aimed to investigate the response to ASMs in term/near term neonates with acute arterial ischemic stroke (AIS), as well as the type of seizure at presentation and the monitoring approach.MethodsWe retrospectively evaluated neonates from 15 European level IV neonatal intensive care units who presented with seizures due to AIS and were monitored by continuous electroencephalography (cEEG) and/or amplitude‐integrated EEG (aEEG) in whom actual recordings, timing, doses, and response to ASMs were available for review.ResultsOne hundred seven neonates were referred, and 88 were included. Of those, 56 met the criteria for evaluating the treatment response. The mean time to treatment was 7.9 h (SD = 16.4), and the most frequently administered first‐line ASM was phenobarbital (PB; 74/88, 84.1%). Seizures were controlled within 24 h from onset of symptoms in 64.3% (36/56) of neonates. Phenytoin (PHT) was effective in almost all neonates in whom it was trialed (24/25, 96.0%), whereas PB was effective in only 22.0% of patients (11/50). Infants treated with PB or PHT as first‐line treatment (53/56, 94.6%) showed a higher response rate with PHT (6/6, 100.0%) than with PB (11/47, 23.4%). Monitoring approach and seizure types were evaluated in 88 infants. Forty‐six of 88 (52.3%) were monitored with cEEG and 47.7% (42/88) with aEEG, with or without intermittent cEEG. The mean monitoring duration was 65.8 h (SD = 39.21). In 83 of 88 (94.3%) infants, the type of seizure suspected clinically prior to monitoring was confirmed afterward. Unilateral focal clonic seizures were seen in 71 of 88 infants (80.7%), whereas 11 of 88 (12.5%) presented with ictal apneas.SignificanceOur findings provide evidence in a large, homogenous cohort that PHT is more effective than PB in treating neonatal acute symptomatic seizures due to AIS.
Application of an Instability‐Based Fracture Model for Prediction of Crack Initiation in Modified 9Cr–1Mo Steel
Authors: Nikhil R. , Krishnan S. A. , Keralavarma S. M. , Moitra A. , Vasudevan M. 
Published: November 2024

ABSTRACTDuctile fracture of modified 9Cr–1Mo steel was investigated using smooth and notched bar tension tests. Round and flat notched specimens with varying notch acuity ratio were used to investigate the influence of stress state on the fracture strain. Simulations of the experiments were performed using the extended finite element method, together with an instability‐based crack initiation criterion based on the micromechanics of void coalescence. The parameters in the plasticity model were determined using smooth bar tension tests, whereas the void nucleation parameters were calibrated from experiments on a shallow‐notched specimen. Subsequently, the load–deflection responses and strain to crack initiation have been predicted for round and flat notched specimens with various notch acuities, and central notched specimens with notches oriented at various angles to the loading axis. Using a single set of parameters, the model was able to quantitatively predict fracture in different specimen geometries encompassing a range of stress states.
Ecological Niche Interaction Between Co‐Existing Antarctic Krill (Euphausia superba) and the Pelagic Tunicate (Salpa thompsoni) in the Northern Antarctic Peninsula
Authors: Chen Zhuang , Zhu Guoping 
Published: November 2024

ABSTRACTAntarctic krill (Euphausia superba; krill) and the pelagic tunicate (Salpa thompsoni; salps) are crucial to the Southern Ocean ecosystem, and krill supports the largest fishery in the Southern Ocean in term of catch. Given recent climatic changes in the northern Antarctic Peninsula (NAP), the distribution of krill and salps are shifting poleward. Unlike krill, salps thrive in warmer water temperatures and can form large blooms under favorable conditions, potentially outcompeting krill for resources. However, krill are ecologically more important, serving as a primary food source for higher trophic levels. The interspecific interactions, including hotspots and ecological niches, of krill and salps in the NAP were therefore investigated using historical datasets and species distribution models. We found that both spatial separation and overlap occurred between krill and salps hotspots, with the primary overlap occurring around Elephant Island. Furthermore, there was a significant overlap in their ecological niches, suggesting that they may have similar ecological requirements. This study emphasized the importance of krill and salps interactions in the Southern Ocean ecosystem. The krill habitat and therefore food web of the Southern Ocean could be influenced significantly if salps continue to shift poleward in the future. The information provided in this study aids in the conservation and management of the Southern Ocean ecosystem.
The Effects of Plant–Microbe–Environment Interactions on Mineral Weathering Patterns in a Granular Basalt
Authors: Milici Valerie R. , Abiven Samuel , Bauser Hannes H. , Bishop Lily G. , Bland Rebecca G. W. , Chorover Jon , Dontsova Katerina M. , Dyer Kielah , Friedman Linus , Rusek‐Peterson Matthew J. , Saleska Scott , Dlugosch Katrina M. 
Published: November 2024

ABSTRACTThe importance of biota to soil formation and landscape development is widely recognized. As biotic complexity increases during early succession via colonization by soil microbes followed by vascular plants, effects of biota on mineral weathering and soil formation become more complex. Knowledge of the interactions among groups of organisms and environmental conditions will enable us to better understand landscape evolution. Here, we used experimental columns of unweathered granular basalt to investigate how early successional soil microbes, vascular plants (alfalfa; Medicago sativa), and soil moisture interact to affect both plant performance and mineral weathering. We found that the presence of soil microbes reduced plant growth rates, total biomass, and survival, which suggests that plants and microbes were competing for nutrients in this environment. However, we also found considerable genotype‐specific variation in plant–microbial interactions, which underscores the importance of within‐species genetic variation on biotic interactions. We also found that the presence of vascular plants reduced variability in pH and electrical conductivity, suggesting that plants may homogenize weathering reactions across the soil column. We also show that there is heterogeneity in the abiotic conditions in which microbes, plants, or their combination have the strongest effect on weathering, and that many of these relationships are sensitive to soil moisture. Our findings highlight the importance of interdependent effects of environmental and biotic factors on weathering during initial landscape formation.
Material Legacies on Coral Reefs: Rubble Length and Bed Thickness Are Key Drivers of Rubble Bed Recovery
Authors: Kenyon Tania M. , Eigeland Karen , Wolfe Kennedy , Paewai‐Huggins Roima , Rowell Devin , Dodgen Tanya , Mumby Peter J. 
Published: November 2024

ABSTRACTDisturbances on coral reefs—which are increasing in intensity and frequency—generate material legacies. These are commonly in the form of rubble beds, which depend on rubble stability and/or binding to facilitate coral recruitment and recovery. Yet, our understanding of rubble stability and binding dynamics across environmental gradients is limited. Characterising and categorising rubble material legacies in context of their likely recovery trajectory is imperative to the effective deployment of active intervention strategies used to restore degraded reefs, such as rubble stabilisation, coral outplanting and larval seeding techniques. We quantified rubble characteristics across environmental gradients on the Great Barrier Reef. The likelihood of rubble stability and binding increased with rubble length and rubble bed thickness, and rubble length was a good predictor of bed thickness and rubble branchiness. Thin rubble bed profiles (< ~10 cm depth), those with small, unbranched rubble pieces (< ~10 cm length), and beds at the base of sloped rubble screes, had lower stability and binding likelihoods. These kinds of beds are expected to persist with low recovery prospects, and could be good candidates for rubble stabilisation interventions. Thicker rubble beds with larger, branched rubble pieces tended to exhibit higher stability and binding likelihoods. However, these beds had nuanced effects on coral cover, and interventions may still be necessary where competition is high, for example from macroalgae. A rapid assessment of rubble length—while also considering shelf location, geomorphic zone, slope angle and underlying substrate—can indicate the potential direction of a rubble bed's recovery trajectory. Our findings have been summarised into a rapid rubble bed assessment tool available in the Supporting Information, that can be incorporated into current reef monitoring to optimize prioritisation of intervention strategies at disturbed sites.
The Impact of Digital Technologies on the Transnational Aging Experience of Older Hong Kongers
Authors: Ngan Lucille Lok Sun 
Published: November 2024

ABSTRACTDespite significant changes brought about by international migration and global population aging, research on older adults has been primarily focused on proximate care and support networks, overlooking the opportunities available to those affected by migration. Filling these gaps, this article draws on in‐depth interviews with 47 older parents (aged 60+) from Hong Kong who are living in transnational family and social contexts to examine how the utilization of digital technologies impacts their daily lives, particularly in relation to transnational aging. Contrary to the conventional assumption that older adults tend to avoid engaging with new technologies, the participants actively embraced digital technologies. This study shows that first, digital technologies can facilitate practical care for older family members across distances, and challenging care for older adults must necessarily be provided in‐person. Second, connecting not only with geographically separated families but also with friends is central to the daily lives of older adults from migrant background, and digital technologies enable such social connections. Third, beyond the role that digital technologies play in fostering interpersonal connections among older adults—a point that is emphasized in the transnational family literature—digitalization also contributes significantly to personal life satisfaction for such people. This study contends that obtaining a comprehensive analysis of aging necessitates a thorough understanding of the influence of digitalization, extending beyond the limits of localized contexts.