bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of SLCO1B1 and APOE genetic polymorphisms in a large ethnic Hakka population in southern China
Authors: Zhong Zhixiong , Wu Heming , Li Bin , Li Cunren , Liu Zhidong , Yang Min , Zhang Qifeng , Zhong Wei , Zhao Pingsen 
Published: February 2018

ObjectiveStatins are the most widely used lipid‐lowering drugs, which have a significant effect on the inhibition of cardiovascular disease. The efficacy and side effects of statins are associated with the polymorphisms of SLCO1B1 and APOE genes. The purpose of this study was to analyze the SLCO1B1 and APOE gene polymorphisms in the Hakka population of southern China.MethodsA total of 3249 subjects including 2019 males and 1230 females participated in this study. Polymerase chain reaction (PCR)‐fluorescence probe technique for polymorphisms analysis and analyzed the genotypes frequencies of SLCO1B1 and APOE genes.ResultsThe frequencies of SLCO1B1 521T>C between men and women were statistically significant (SLCO1B1 521TT, χ2 = 8.431, P = .004; SLCO1B1 521TC, χ2 = 7.436, P = .007). The frequencies of haplotypes *1b/*1b (40.07%) and *1a/*1b (32.56%) of SLCO1B1 gene accounted for 72.63%, followed by *1b/*15(14.40%), *1a/*1a (5.82%), *1a/*15 (5.57%), *15/*15 (1.45%), and *1a/*5 (0.12%). The frequencies of haplotypes *1a/*15 and *1b/*1b of SLCO1B1 gene between men and women were statistically significant (*1a/*15, χ2 = 6.789, P = .009; *1b/*1b, χ2 = 3.998, P = .004). In this study, genotype ɛ3/ɛ3 accounted for 69.04%, followed by ɛ3/ɛ4 (16.19%), ɛ2/ɛ3 (11.60%), ɛ2/ɛ4 (1.35%), ɛ4/ɛ4 (1.08%), and ɛ2/ɛ2 (0.74%) in all subjects, in which ɛ3 had the greatest allele frequency (82.93%), followed by ɛ4 (9.85%) and ɛ2 (7.22%). We found that 47 subjects carrying the SLCO1B1 521 (CC) polymorphism who had not any myopathy caused by statins.ConclusionsWe analyzed the SLCO1B1 and APOE gene polymorphisms in the Hakka population of southern China. This study provides a reference for the individualized meditation for Hakka population in this area.
Extensions of a theorem of Erdős on nonhamiltonian graphs
Authors: Füredi Zoltán , Kostochka Alexandr , Luo Ruth 
Published: February 2018

AbstractLet be integers with , and set . Erdős proved that when , each n‐vertex nonhamiltonian graph G with minimum degree has at most edges. He also provides a sharpness example for all such pairs . Previously, we showed a stability version of this result: for n large enough, every nonhamiltonian graph G on n vertices with and more than edges is a subgraph of . In this article, we show that not only does the graph maximize the number of edges among nonhamiltonian graphs with n vertices and minimum degree at least d, but in fact it maximizes the number of copies of any fixed graph F when n is sufficiently large in comparison with d and . We also show a stronger stability theorem, that is, we classify all nonhamiltonian n‐vertex graphs with and more than edges. We show this by proving a more general theorem: we describe all such graphs with more than copies of for any k.
Using a network of ports for shielding effectiveness optimization of an enclosure with arbitrary shape apertures
Authors: Shourvarzi Ali , Joodaki Mojtaba 
Published: February 2018

AbstractA network of ports will be used to determine the optimized locations and geometries for arbitrary shape apertures on a metallic enclosure. This approach benefits from S‐parameter analysis and circuit theory for the description of the shielding. An analytic discussion will show the validity of the new method, which is based on a recently published paper. The consistency of the results for case studies solved by this port network with both literature and 3‐D full‐wave computed results will show the practicality of the proposed method. The positive effect of symmetry is a major outcome of the case study discussed here. Although the method is theoretically verified here, it can be easily implemented as a simple and reliable shielding effectiveness measurement method. The proposed method obliterates the limits of the traditional simulation and experimental methods as it has no dimensional limits and no need for antennas, shielded rooms, reverberation chambers, etc.
State and Trait Anger Predicting Creative Process Engagement—The Role of Emotion Regulation
Authors: da Costa Carla Gomes , Zhou Qin , Ferreira Aristides I. 
Published: February 2018

AbstractDrawing on the specific emotion approach, and based on the emotional regulation theory and cognitive and activation perspectives on emotions, this study examined the differentiated impact of state and trait anger on creative process engagement (CPE) and the moderating influences of emotion reappraisal and suppression. Data were obtained from daily surveys (N = 422) of 98 employees from three consultancy companies. Hierarchical linear modeling analysis revealed that trait anger has a stronger impact on CPE than state anger does. Furthermore, the relationship between state anger and CPE is stronger when emotion reappraisal is lower, rather than higher, and the relationship between trait anger and CPE is also stronger when emotion suppression is lower, rather than higher.
Character and origin of De Geer moraines in the Seacoast region of New Hampshire, USA
Authors: Sinclair Samantha N. , Licciardi Joseph M. , Campbell Seth W. , Madore Brian M. 
Published: February 2018

ABSTRACTPreviously unrecognized clusters of regularly spaced, low‐relief ridges were recently revealed by LiDAR data acquired in the Seacoast region of New Hampshire, USA. Based on their morphometry and geologic context, these features are interpreted as De Geer moraines that formed during regional deglaciation. While De Geer moraines are widely recognized as products of ice recession in glaciomarine settings, their formative processes remain debated. Here, we integrate geospatial mapping, morphometric analyses, stratigraphic investigations and ground‐penetrating radar (GPR) subsurface profiling to characterize De Geer moraines in New Hampshire and assess their origin. On average, the moraines are 1.2 km long, 28 m wide, 1.7 m tall and spaced 104 m apart. Trenches expose stratigraphic units consistent with subaqueous deposition along a tidewater glacier margin, including subglacial traction till indicative of proglacial pushing, and gravity‐driven flow deposits on an ice‐distal moraine slope. GPR profiles reveal variable till thicknesses beneath the ridges and stratified sediment in adjacent swales. Our findings suggest De Geer moraine formation was driven by annual oscillations of the retreating Laurentide Ice Sheet margin. In this interpretation, average moraine spacing would represent a retreat rate of ∼100 m a−1, which is in line with previous estimates of recession rates across New England.
Evaluation of Soy Lecithin as Eco‐Friendly Biosurfactant Clathrate Hydrate Antiagglomerant Additive
Authors: Saikia Tinku , Mahto Vikas 
Published: February 2018

AbstractHydrate plug formation is one of the most challenging problems in upstream oilfields. The most preferred option to prevent hydrate plug formation is the use of antiagglomerants in the oil/gas flowlines and in drilling fluids. Antiagglomerants do not prevent hydrate formation but restrict the hydrate crystals from agglomerating. In this study, experiments were conducted on of soy lecithin (biosurfactant) at different concentrations to measure its effectiveness as an antiagglomerant additive. In all the experiments, tetrahydrofuran (THF) hydrate was used, and to study the antiagglomerant efficiency of the additive, visual observation was utilized. Soy lecithin was compared with cetyltrimethylammonium bromide (CTAB), and the former was found as a good environmentally friendly antiagglomerant additive. Soy lecithin at 0.1 wt% in the experimental solution increased the agglomeration time of hydrate crystals by more than 1440 min and showed agglomeration state III at 1 °C. Soy lecithin at 0.01 wt% increased the agglomeration time of hydrate crystals to 1000 min. The effect of soy lecithin on the rheological characteristics and filtration properties of drilling fluid was also studied. Even at the highest concentration of 1.0 wt% soy lecithin and at a temperature of 1 °C, the rheological parameters of the drilling fluid remained within permissible limits. Soy lecithin was thus found to effectively restrict the agglomeration of hydrate crystals.
Arable weed species associated with soil tillage systems under Mediterranean conditions
Authors: Santín‐Montanyá M.I. , Casanova Pena C. , Zambrana Quesada E. , Sánchez Jiménez F.J. , Tenorio Pasamón J.L. 
Published: February 2018

AbstractTillage soil erosion is seen as a great problem in the Mediterranean region and is worsened by the climatic conditions. Previous studies have shown a decrease in biodiversity in arable lands across Europe. Weeds are a major component of biodiversity within agro‐ecosystems, but few studies have aimed to associate weed species with soil tillage intensity. We performed an analysis to test the potential short‐term effects of different tillage systems on weed species under our study conditions. The emerged weed data were measured, comparing a conventional tillage system with conservational tillage systems (minimum tillage and no tillage) in 2 cropping systems (monoculture wheat and a rotation scheme of barley–legume–wheat–fallow). Compared with the tilled soil, higher weed density and weed species richness were observed in the conservation tillage plots. The weed density and weed species richness in the monoculture system were higher compared with those in the crop rotation system. We used classification and regression trees to analyze the relationship between the soil tillage systems and the weed community, taking into account the climatic conditions. The results indicate that different soil tillage systems produced tree models:Silene vulgaris(L.) was associated with the MT system and high and irregularly distributed rainfall;Hypecoum imberbeSm. andHypecoum procumbens(L.) were linked to MT plots with low and well‐distributed precipitation rates; andCardaria draba(L.) was present all years independently of climatic conditions but was never found in the NT system, so its presence could be regarded as an indicator of tillage intensity.
Antecedents and consequences of chronic impulsive buying: Can impulsive buying be understood as dysfunctional self‐regulation?
Authors: Fenton‐O'Creevy Mark , Dibb Sally , Furnham Adrian 
Published: February 2018

AbstractResearchers reach different conclusions about the functional or dysfunctional nature of impulsive buying behavior. While many note the use of impulsive buying as a form of mood regulation, there is disagreement about whether this is functional or dysfunctional and the extent to which it causes financial harm. This paper draws on data from a U.K. national survey sample (N = 109,472) to contribute to these debates. Study results suggest that impulsive buying is more common for those who have most need to regulate mood and who have the least effective emotion regulation strategies. This suggests that impulsive buying may be understood as a failure of self‐regulation in relation to long‐term goals and as a strategy for mood regulation. Contrary to some prior claims in the retail management and marketing research literature, the study shows higher levels of impulsive buying to be associated with more adverse financial outcomes (which are not confined to the most extreme manifestations of the trait). While ineffective emotion regulation is associated with higher propensity to buy impulsively, the findings also suggest that effective emotion regulation may to some extent mitigate the adverse consequences of the propensity to buy impulsively. The implications for ethical management, research, and policy are considered.
Will they pitch or will they switch? Comparing Chinese and American consumers
Authors: Krishen Anjala S. , Hu Han‐Fen 
Published: February 2018

AbstractThis study compares the conditions for consumer satisfaction and word of mouth (WOM) between Chinese and American consumers. The authors utilize a between‐subjects factorial design experiment to investigate the effect of service experience (positive or negative) and consumption context (hedonic vs. utilitarian) across these two cultures. Results indicate that consumers perceive higher levels of satisfaction and switching costs, and provide higher WOM intention for positive than for negative service experiences. The relationship between service experience and perceived switching costs is further moderated by consumption context and culture. Of importance is the critical mediating role of consumer satisfaction in driving perceived switching costs and WOM intention. The comparison of Chinese and American consumers also reveals the distinct switching behaviors between the two groups of consumers, which can be explained from a cultural perspective. The study findings provide insights into provider‐switching and WOM‐spreading behaviors by Chinese and American consumers, under hedonic versus utilitarian consumption contexts.
Do they shop to stand out or fit in? The luxury fashion purchase intentions of young adults
Authors: Eastman Jacqueline K. , Iyer Rajesh , Shepherd C. David , Heugel Angelina , Faulk Don 
Published: February 2018

AbstractA three‐study examination of young adults suggests that their motivation for status in terms of their luxury fashion purchase intentions is impacted by a bandwagon effect. In Study 1, qualitative research informs what fashion items represent status to young adults, how they view these items, and how they view others owning these items. In Study 2, survey research establishes the link between the motivation for status (status consumption) and purchase intention/ownership of these fashion items. In Study 3, a national survey of young adults examines what mediates and moderates the motivation for status to lead to luxury fashion purchase intentions. Results from the three studies indicate that status consumption has a positive impact on purchase intention of luxury fashion. This research also finds that cultural variables have an impact (mediate) the relationship between status consumption and purchase intention. Specifically, collectivism, uncertainty avoidance, power distance, and masculinity mediate the relationship between status consumption and purchase intention. Finally, the moderating impact of the bandwagon effect has a significant effect on the relationship between status consumption and fashion purchase intention for the cultural variables of uncertainty avoidance, long‐term orientation, and power distance. Implications for marketers are provided based on the findings.
Autoinducer2 affects trimethoprim‐sulfamethoxazole susceptibility in avian pathogenic Escherichia coli dependent on the folate synthesis‐associate pathway
Authors: Yu Lumin , Li Wenchang , Zhang Ming , Cui Yunmei , Chen Xiaolin , Ni Jingtian , Yu Li , Shang Fei , Xue Ting 
Published: February 2018

AbstractAvian pathogenic Escherichia coli (APEC) causes airsacculitis, polyserositis, septicemia, and other mainly extraintestinal diseases in chickens, ducks, geese, pigeons, and other avian species, and is responsible for great economic losses in the avian industry. The autoinducer 2 (AI‐2) quorum sensing system is widely present in many species of gram‐negative and gram‐positive bacteria and has been proposed to be involved in interspecies communication. In clinical APEC strains, whether or not AI‐2 affects the expression of antibiotic‐related genes has not been reported. In this study, we have reported that exogenous AI‐2 increase the susceptibility of APEC strains to trimethoprim‐sulfamethoxazole (SXT) in a folate synthesis‐dependent pathway but not in the LsrR‐dependent manner. Our results further explained that exogenous AI‐2 can down regulate the transcription of the folate synthetase encoding genes folA and folC, and the folate synthesis‐related genes luxS, metE, and metH. Gel shift assays confirmed that LsrR, the AI‐2 receptor, did not bind to the promoters of folA and folC, suggesting that exogenous AI‐2 might influence folate metabolism by a feedback inhibition effect but not in the LsrR‐dependent pathway. This study might provide further information in the search for potential drug targets for prophylaxis of avian colibacillosis and for auxiliary antibiotics in the treatment of avian colibacillosis.
CLCN1 Myotonia congenita mutation with a variable pattern of inheritance suggests a novel mechanism of dominant myotonia
Authors: Gaitán‐peñas Héctor , Armand‐Ugón Mercedes , Macaya Alfons , Estévez Raúl 
Published: February 2018

ABSTRACTIntroduction: Mutations in CLCN1 cause recessive or dominant forms of myotonia congenita (MC). Some mutations have been found to exhibit both patterns of inheritance but the mechanism explaining this behavior is unknown. Methods: A known recessive missense mutation, A493E, was identified in a family with dominant MC. The mutant p.A493E alone or in co‐expression with wild‐type (WT) ClC‐1 was expressed in Xenopus oocytes. Currents were measured and biochemical assays were performed. Results: The mutant showed no significant activity and reduced total and plasma membrane (PM) protein levels. Co‐expression with the mutant reduced the activity and PM levels of an engineered lower expression variant of ClC‐1, whereas no effect was observed on a higher expression variant. Discussion: Our results suggest that the dominant effect of some CLCN1 mutations showing recessive or dominant inheritance patterns may be due to a dose‐dependent defect in PM delivery of the WT channel. Muscle Nerve 58: 157–160, 2018
Oil‐Repellent Optics for Wastewater Sensor Applications
Authors: Oberbillig Thomas , Felde Nadja , Franz Martin , Coriand Luisa , Dahms Nancy , Munderloh Karin , Schultz Karin , Fliedner Michael , Duparré Angela 
Published: February 2018

AbstractA fundamental issue for the identification of environmental problems is the early detection of chemical water pollutants. To guarantee reliable measurement results and to reduce maintenance costs, soiling of the sensor surfaces should be minimized. This work presents a method for fabrication of optical and oil‐repellent functional surfaces, realized by combination of statistically produced nano‐roughness with adapted coating materials.
Corporate values of the 25 largest European banks: Exploring the ambiguous link with corporate scandals
Authors: Ehrenhard Michel L. , Fiorito Timo L. 
Published: February 2018

Corporate value statements communicate what a firm aspires for and what drives their value creation. In addition, corporate values often also define which behaviors are acceptable and which are not. Ideally, corporate values are representations of a firm's informal corporate values and organizational culture. However, in practice, there is an inherent tension between the aspirations and actual values and ensuing behaviors of and within a firm—let alone the potentially different interpretations of abstract corporate value statements. In this paper, we set out to provide more clarity on what corporate values are, how they are inherently ambiguous, and how in practice they compare to firm involvement in scandals. For this purpose, we study the corporate values of the 25 largest European banks after the financial crisis. “Integrity” appeared to be the most common value among the 25 banks, followed by “customer focus.” Nonetheless, over the past 6 years, 15 out of the 25 studied banks were involved in one or more scandals. Scandals can be systematic or caused by rogue employees, and benefitting the firm or their customers—in the latter case, providing an interesting interpretation of the customer focus value. Additionally, we found that courage or its synonyms were barely mentioned among banks' corporate values, potentially providing an additional explanation for the fast size of the financial crisis. Finally, we found that banks that had inclusive social principles such as respect, solidarity, and equality did not face large‐scale scandals.
Taxus ingredients in the red arils of Taxus baccata L. determined by HPLC‐MS/MS
Authors: Siegle Lydia , Pietsch Jörg 
Published: February 2018

AbstractIntroductionTaxus baccata L. is an evergreen conifer whose plant parts are cardiotoxic. Only the red arils of the berries are described as non‐toxic and taxane‐free.ObjectiveExtraction and HPLC‐MS/MS methods were developed for the investigation of the Taxus compounds 3,5‐dimethoxyphenol, 10‐deacetylbaccatin III, baccatin III, cephalomannine, taxol A and taxinine M in the red arils of the yew berries.MethodologyA liquid–liquid extraction method for the red arils of the fruits from three yews were developed. An accurate (ESI+) HPLC‐MS/MS method was performed for the simultaneous detection and determination of the target compounds in multiple reaction monitoring (MRM) mode.ResultsAll Taxus agents obtained were detected in the red arils. Highest concentrations were determined for baccatin III and 10‐deacetylbaccatin III.ConclusionThe developed quantitative method is reliable and selective and was successfully applied for quantification of selected Taxus ingredients in red arils of Taxus baccata. It was disproved that the red arils of the berries do not contain the selected Taxus compounds.
Dynamic covalent polymer hydrogels and organogels crosslinked through acylhydrazone bonds: synthesis, characterization and applications
Authors: Apostolides Demetris E , Patrickios Costas S 
Published: February 2018

AbstractWe review recent literature on the rapidly expanding field of dynamic covalent polymer networks (DCPNs) crosslinked with acylhydrazone bonds, classified according to their structural perfection: randomly crosslinked and model DCPNs. The dynamic covalent acylhydrazone bond is greatly sensitive to environmental conditions, pH in particular, and is characterized by great stability under neutral and mildly alkaline conditions, and instability under acidic conditions. The dynamic nature of this bond endows DCPNs crosslinked with acylhydrazone bonds with self‐healing ability, reversibility and injectability. The last property enables the in vivo site‐specific delivery of drugs, biomolecules or cells that have been loaded into DCPN hydrogels. © 2018 Society of Chemical Industry
Solubility of polystyrene with various molecular weights in subcritical 1,1,1,2‐tetrafluoroethane: experiment and modified model
Authors: Jin Junsu , Guo Lintao , Chang Chengwei , Meng Hong 
Published: February 2018

AbstractThe solubility of polystyrene with molecular weight of 100 000 and 260 000 g mol−1was measured at temperatures from 313 to 333 K and at pressures from 5.0 to 13.0 MPa in subcritical 1,1,1,2‐tetrafluoroethane (R134a). The effects of pressure, temperature and molecular weight on the solubility of polystyrene were investigated. Meanwhile, the solubility of polystyrene was correlated using six density‐based semi‐empirical models (Chrastil, A‐L, K‐J, S‐S, M‐S‐T and Bartle). The M‐S‐T model was used to verify the self‐consistency of the experimental data, and the enthalpy values of polystyrene, including ΔHtotal, ΔHsuband ΔHsol, were estimated through the Chrastil and Bartle models. In addition, a modified M‐S‐T model was proposed through a detailed study of semi‐empirical model formulas and verified by the solubility of polystyrene in subcritical R134a and 38 other solid solutes in supercritical carbon dioxide and subcritical R134a. © 2018 Society of Chemical Industry