bluuebunny/crossref_metadata_2025_split huggingface dataset:
Educational Leadership in Teaching Excellence (EnLITE): A Peer-Driven Faculty Development Program
Authors: Buchholz Andrea C. , Wolstenholme Janet , Varghese Jeji , Robinson J. Andrew , Spencer Jennifer , Reniers Jennifer 
Published: September 2019

Educational Leadership in Teaching Excellence (EnLITE) is an 11-month faculty development program at the University of Guelph, Ontario. Created and led by faculty members and educational developers, EnLITE is designed to engage participants in the principles, practice and theory of teaching and learning in higher education and to promote a learner-centred approach to teaching. Participants critically examine and discuss scholarly topics on teaching and learning and in their own disciplines; collaborate with one or more teaching mentors; engage in peer classroom observation; and participate in other teaching-related activities informed by their individual learning plans. Our objective was to determine the perceived impact of EnLITE on participants’ teaching-related practices and experiences. We collected pre-, post- and one-year post-program quantitative and qualitative survey responses from each of the 2014-2015, 2015-2016 and 2016-2017 EnLITE cohorts (N = 17 participants representing a variety of disciplines; 71% female). There were significant improvements in participants’ perceived teaching practices related to critical self-reflection (13% increase from pre- to one-year post-program), student engagement (+28.2%), collaborative learning (+31%) and learner-centred pedagogy (+22.9%, all p < 0.05). There was little to no change in use of technology, student assessment, leadership, participation in communities of practice, or dissemination of teaching-related scholarship. These results provide empirical evidence of the effectiveness of a peer-driven faculty development program in promoting a learning-centred approach to teaching. Future research should determine whether these changes translate into improved student learning, and whether such programs demonstrate longer term improvements in engagement in teaching-related leadership, communities of practice and dissemination.
The Possible Learning and Teaching Benefits of Short Mind-calming Exercises in Undergraduate Courses
Authors: Grogan Paul 
Published: September 2019

The potential benefits of meditation exercises to promote more focused student attention and engagement have only rarely been quantitatively investigated at the college/university level. Here, I report student perceptions on the impacts of regular short mind-calming exercises at the beginning of every class in second, third, and fourth-year biology undergraduate courses, using voluntary anonymous surveys that were completed by at least two-thirds of each class (total enrollments 326, 68, and 15 respectively).
In the third year course, 93% of respondents indicated that the exercise was “enjoyable and relaxing”, 73% indicated that it was “a valuable use of lecture time because I feel it enhances deep learning”, 75% found it a useful perspective “to achieving balance/calm in my life”, and 76% rejected the suggestion that although “the exercises are useful, they are not course-related material and therefore are inappropriate within class time”. Responses to several other distinct survey statements were also strongly positive, and furthermore, very similar favourable results as above were obtained in the other two courses. Overall, although it is unclear whether these very short exercises actually enhanced learning, many students perceived that it did. Finally, my teaching performance in university-based student assessments of the third-year course was significantly elevated in the year with mind-calming exercises compared to each of the previous nine iterations in which I had been an instructor. Together, these quantitative results suggest that the regular use of such exercises has multiple direct and indirect benefits that may contribute to more effective undergraduate learning and teaching.
<b>Asymptotically Lacunary Statistical Equivalent Sequences of Fuzzy Numbers</b> - doi: 10.5269/bspm.v30i2.14007
Authors: Esi Ayhan , Çatalbas Necdet 
Published: September 2019

In this article we present the following definition which is natural combination of the definition for asymptotically equivalent and lacunary statistical convergence of fuzzy numbers. Let =(k_{r}) be a lacunary sequence. The two sequnces X = (X_{k}) and Y=(Y_{k}) of fuzzy numbers are said to be asymptotically lacunary statistical equivalent to multiple L provided that for every >0lim_{r}(1/(h_{r}))|{k∈I_{r}:d(((X_{k})/(Y_{k})),L)≥}|=0.
A propósito de la nulidad del despido y la resolución de liquidación concursal. Comentario a la sentencia de la Corte Suprema Rol N° 31.772-2017 de 08 de marzo de 2018
Authors: Ruay Sáez Francisco 
Published: September 2019

En el presente comentario de jurisprudencia pretendemos analizar el criterio actual de la Corte Suprema en materia de sanción de nulidad del despido y su relación con la dictación de una resolución de liquidación concursal en materia comercial.
Se expone de manera genérica cuál fue el escenario previo a la reforma, cuál ha sido la intención del legislador al modificar sustancialmente el modelo concursal chileno, a fin de plantear un análisis crítico del alcance de los mismos.
A Nanoscale Investigation of Carlin-Type Gold Deposits: An Atom-Scale Elemental and Isotopic Perspective
Authors: Gopon Phillip , Douglas James O. , Auger Maria A. , Hansen Lars , Wade Jon , Cline Jean S. , Robb Laurence J. , Moody Michael P. 
Published: September 2019

Abstract
Carlin-type gold deposits are one of the most important gold mineralization styles in the world. Despite their economic importance and the large volume of work that has been published, there remain crucial questions regarding their metallogenesis. Much of this uncertainty is due to the cryptic nature of the gold occurrence, with gold occurring as dispersed nanoscale inclusions within host pyrite rims that formed on earlier formed barren pyrite cores. The small size of the gold inclusions has made determining their nature within the host sulfides and the mechanisms by which they precipitated from the ore fluids particularly problematic.
This study combines high-resolution electron probe microanalysis (EPMA) with atom probe tomography (APT) to constrain whether the gold occurs as nanospheres or is dispersed within the Carlin pyrites. APT offers the unique capability of obtaining major, minor, trace, and isotopic chemical information at near-atomic spatial resolution. We use this capability to investigate the atomic-scale distribution of trace elements within Carlin-type pyrite rims, as well as the relative differences of sulfur isotopes within the rim and core of gold-hosting pyrite.
We show that gold within a sample from the Turquoise Ridge deposit (Nevada) occurs within arsenian pyrite overgrowth (rims) that formed on a pyrite core. Furthermore, this As-rich rim does not contain nanonuggets of gold and instead contains dispersed lattice-bound Au within the pyrite crystal structure. The spatial correlation of gold and arsenic within our samples is consistent with increased local arsenic concentrations that enhanced the ability of arsenian pyrite to host dispersed gold (Kusebauch et al., 2019). We hypothesize that point defects in the lattice induced by the addition of arsenic to the pyrite structure facilitate the dissemination of gold. The lack of gold nanospheres in our study is consistent with previous work showing that dispersed gold in arsenian pyrite can occur in concentrations up to ~1:200 (gold/arsenic). We also report a method for determining the sulfur isotope ratios from atom probe data sets of pyrite (±As) that illustrates a relative change between the pyrite core and its Au and arsenian pyrite rim. This spatial variation confirms that the observed pyrite core-rim structure is due to two-stage growth involving a sedimentary or magmatic-hydrothermal core and hydrothermal rim, as opposed to precipitation from an evolving hydrothermal fluid.
The Influence of CO2 on the Solubility of Quartz in Single-Phase Hydrothermal Fluids: Implications for the Formation of Stockwork Veins in Porphyry Copper Deposits
Authors: Monecke Thomas , Monecke Jochen , Reynolds T. James 
Published: September 2019

Abstract
Porphyry copper deposits consist of low-grade stockwork and disseminated sulfide zones that contain characteristic vein generations formed during the evolution of the hydrothermal systems. The present contribution examines the influence of variable CO2 concentrations on the solubility of quartz in single-phase hydrothermal fluids forming stockwork veins in porphyry deposits at temperatures of 150° to 550°C and pressures ranging from 100 to 2,000 bar at concentrations up to 8 mol % CO2. The calculations demonstrate that quartz solubility in hydrothermal fluids decreases with increasing CO2 content. Retrograde quartz solubility is less pronounced in CO2-bearing fluids and is not observed in single-phase fluids having CO2 concentrations exceeding 6 mol %.
Despite the effects of CO2, retrograde quartz solubility plays an important role in the formation of porphyry stockwork veins that contain little or no quartz as a gangue mineral. At high temperatures and lithostatic pressure conditions below 900 bar, early biotite veins can form as a result of quasi-isobaric cooling of single-phase hydrothermal fluids under conditions of retrograde quartz solubility or near-constant quartz solubility. Stock-work veins consisting of molybdenite or hypogene copper sulfide minerals lacking quartz could form at temperatures of up to 450°C under hydrostatic pressures ranging from ~250 to 900 bar. In the presence of CO2, retrograde quartz solubility is shifted toward slightly lower temperatures at constant pressure. At temperatures below ≾375°C, quartz is precipitated during quasi-isobaric cooling irrespective of CO2 content of the hydrothermal fluids, resulting in the formation of late porphyry quartz veins.
The Carboniferous Shikebutai Iron Deposit in Western Tianshan, Northwestern China: Petrology, Fe-O-C-Si Isotopes, and Implications for Iron Pathways
Authors: Yang Xiuqing , Mao Jingwen , Jiang Zongsheng , Santosh M. , Zhang Zuoheng , Duan Shigang , Wang Dachuan 
Published: September 2019

Abstract
Submarine volcanic-hosted iron deposits are important sources of iron ore in northwestern China. Here we present the petrological characteristics and coupled Fe-O, C, and Si isotope data of iron ores from the Shikebutai submarine volcanic-hosted hematite deposit in the Western Tianshan region. Several stratiform and lenticular hematite-dominated orebodies occur in Carboniferous submarine volcano-sedimentary sequences in this region. The ores are mainly composed of hematite, quartz, and minor siderite with distinct alternating iron-rich and silica-rich bands. The hematite shows δ56Fe and δ18O values in the range of –0.31 to 0.80‰ and 2.2 to 7.0‰, respectively, and the jasper yields δ30Si values of –1.90 to –1.20‰. Iron and Si were both derived from hydrothermal fluids related to submarine magmatism/volcanism. The Fe-bearing minerals in the Shikebutai deposit define distinct formation pathways. Hematite is the primary dehydrated Fe(III) oxyhydroxide, and the Fe isotope data indicate fractionation resulting from the partial oxidation of Fe(II). The O isotope data reflect inheritance from the submarine hydrothermal fluids source. Jasper was produced during coprecipitation of silica adsorbed onto the Fe(III) oxyhydroxides. The siderite-rich iron ore/volcaniclastic rock samples with a high and variable total organic carbon content (0.14–5.57%) show negative δ13C values (–3.0 to –1.1‰) and light δ56Fe values (–1.11 to –0.84‰). Our isotope data, together with the common occurrence of hematite inclusions in siderite, suggest that siderite was mainly produced by microbial dissimilatory iron reduction during diagenesis. The geologic, petrological, and isotopic data suggest that the Carboniferous Shikebutai deposit was precipitated through chemical and biogenic processes.
Re-evaluation of conditional probability of rupture of the Wellington-Hutt Valley segment of the Wellington Fault
Authors: Rhoades D.A. , Van Dissen R.J. , Langridge R.M. , Little T.A. , Ninis D. , Smith E.G.C. , Robinson R. 
Published: September 2019

New information on the activity of the Wellington-Hutt Valley segment of the Wellington Fault, New Zealand, has become available from geological and modelling studies undertaken in the last several years as part of the “It’s Our Fault” project. There are now revised estimates of: 1) the timing of the most recent rupture, and the previous four older ruptures; 2) the size of single-event displacements; 3) the Holocene dextral slip rate; and 4) rupture statistics of the Wellington-Wairarapa fault-pair, as deduced from synthetic seismicity modelling. The conditional probability of rupture of this segment over the next 100 years is re-evaluated in light of this new information, assuming a renewal process framework. Four recurrence-time distributions (exponential, lognormal, Weibull and Brownian passage-time) are explored. The probability estimates take account of both data and parameter uncertainties. A sensitivity analysis is conducted, entertaining different bounds and shapes of the probability distributions of important fault rupture data and parameters. Important findings and conclusions include:

The estimated probability of rupture of the Wellington-Hutt Valley segment of the Wellington Fault in the next 100 years is ~11% (with sensitivity results ranging from 4% to 15%), and the probability of rupture in the next 50 years is about half of that (~5%).
In all cases, the inclusion of the new data has reduced the estimated probability of rupture of the Wellington Fault by ~50%, or more, compared to previous estimates.
Evaluation of Iron Supplementation Effects on Plasma Lipid Levels in Pregnant Women
Authors: Omer Safa F. , Elnour Suaad , Modawe GadAllah 
Published: September 2019

Backgrounds: Iron supplementation is most widely used approach of controlling the global problem of iron deficiency anemia especially in pregnant anemic women. Anemia is one of the most frequent complications related to pregnancy. Normal physiological changes in pregnancy affect the hemoglobin (Hb), Epidemiological studies have shown high serum iron concentrations following abnormal levels of blood lipids are risk factors for coronary artery disease and myocardial infarction. Both iron deficiency anemia and dyslipidaemia are widely prevalent public health problems, especially in the Sudanese pregnant women.
Objectives: The aim of present study was to measure the serum level of lipids profile in anemic pregnant women compared to non anemic pregnant women.
Methodology and Study Population: The analytical case control study conducted in obstetrics and gynecology centre, Omdurman city, Khartoum state. One hundred subjects known with 50 pregnant anemic as case groups and 50 non anemic pregnant women as control groups were enrolled in this study, with match age and sex, the age ranged between (20 to 40 years) and their mean (31.7±4.34). The serum lipid profile was analyzed using spectrophotometric method.
Results: The (mean±SD) of Hb, HDL, LDL, TG and TC in anemic pregnant women respectively were (68.15±9.35, 46.06±9.62, 114.14±36.86, 170.38±54.57. 197.16±46.83). While the (mean±SD) of Hb, HDL, LDL, TG and TC in non anemic pregnant women respectively were (79.76±7.22, 47.44±9.65, 140.00±40.76, 189.72±37.89, 224.38±45.09). The concentration of Hb was highly significantly decrease in anemic pregnant compare to non anemic pregnant women with p value (p=0.000). The level serum of LDL, TG and TC were significantly decrease in anemic pregnant compare to non anemic pregnant women with p value (p= 0.001, 0.042, 0.004) respectively. The age of study population were no correlation with serum LDL(r= -0.155, p= 0.283), HDL(r= -0.019, p=0.898) and TC (r=0.68, p=0.640). And also their positive correlation between age and serum TG (r= 0.286, P=0.044).
Conclusion: The anemic pregnant women had a significantly decreased of Hb and serum LDL, TG and TC and also their positive correlation between age and serum TG.
Determination of combination therapy prescribing patterns for the treatment of acute agitation in psychiatric patients: A regression model of patient diagnoses and demographics
Authors: Maas Mark S. , Moeller Karen E. , Melton Brittany L. 
Published: September 2019

Abstract

Introduction
Guidelines for the treatment of acute agitation typically recommend monotherapy with an antipsychotic or a benzodiazepine, but combination therapy is frequently used in practice. We created a regression model to identify which factors lead to the prescribing of combination therapy for acute agitation on a psychiatry unit.

Methods
We collected retrospective data from hospitalized patients in the psychiatry unit. An a priori alpha of 0.05 was used for binary logistic regression models to determine if and how the number of prescribed medications for acute agitation was influenced by: age, sex, race, cardiovascular comorbidities, and psychiatric diagnoses.

Results
We identified 1998 encounters from 1200 patients. Patients are significantly more likely to be prescribed combination therapy if they are young, male, and of non-white race or have a diagnosis of central nervous system stimulant use, hallucinogen use, depression, bipolar, cluster B personality, or psychosis. Patients are significantly more likely to be prescribed monotherapy if they have cardiovascular comorbidity or have neurocognitive disorder.

Discussion
Several demographic or diagnostic factors predict combination therapy prescribing. Acute agitation guidelines should be reviewed to include more clear instructions on combination therapy use.
Adverse outcomes of abrupt switch and discontinuation of acetylcholinesterase inhibitors in dementia with Lewy bodies: Case report and literature review
Authors: Greiman Tristyn L. , Dear Brittani N. , Wilkening G. Lucy 
Published: September 2019

Abstract
Due to the well-defined risks of abrupt discontinuation of certain psychiatric medications, such as withdrawal and worsening symptoms, guideline recommendations describe evidence-based strategies for tapering some psychiatric medications, such as antidepressants. Despite widespread use of acetylcholinesterase inhibitor (ACHEI) therapy in the management of dementia, guideline recommendations for discontinuation of these therapies are very inconsistent. Specifically, studies and evidence-based recommendations for discontinuing ACHEIs in patients with dementia with Lewy bodies (DLB) are severely lacking. This deficit is problematic in that emerging reports suggest several adverse outcomes, such as worsening cognition and behavioral symptoms, are associated with abrupt switching and discontinuation of ACHEI therapy in this population. A case of rapid cognitive and functional decline following both abrupt switch and discontinuation of donepezil in a patient diagnosed with DLB is presented. A literature review of outcomes following changes in ACHEI therapy in DLB is also presented.
Lithium-induced hypercalcemia with normal parathyroid hormone: A case report
Authors: Dorflinger Charles , Fuller Matthew 
Published: September 2019

Abstract
Long-term use of lithium is a known risk factor for hypercalcemia often due to involvement of the parathyroid gland. Because of this, lithium-induced hypercalcemia typically occurs simultaneously with abnormal parathyroid hormone concentrations. This case report describes a 54-year-old white male who has received lithium therapy intermittently for more than 10 years. During admission to an acute inpatient psychiatric unit, the patient experienced hypercalcemia with normal parathyroid hormone concentrations and no other discernible cause. Based on the Naranjo algorithm, lithium was determined to be the probable cause of hypercalcemia. Current literature suggests that lithium-induced hypercalcemia occurs secondary to hyperparathyroidism; however, this case may provide evidence of another, unidentified cause.
Possible varenicline withdrawal-induced akathisia: A case report
Authors: Smith Thomas R. , Dabaja Marwah H. , Farhat Marwa J. 
Published: September 2019

Abstract
Akathisia is a relatively common adverse effect that may emerge during treatment with antipsychotics and other medication classes. We present a case of akathisia that may have been induced by the abrupt discontinuation of varenicline and review existing literature related to this phenomenon. A 46-year-old female with a past psychiatric history of bipolar disorder and borderline personality disorder was admitted to the acute psychiatric services department for suicidal ideation after 3 weeks of a new course of varenicline. This was prescribed for smoking cessation and titrated to 1 mg twice daily. Upon admission, the varenicline was discontinued. Roughly 3 days later, the patient began to complain of akathisia. The patient had experienced akathisia previously while taking antipsychotics for her bipolar disorder and was able to recognize its emergence. As the akathisia worsened, propranolol 10 mg 3 times daily was ordered and was effective in relieving her symptoms. A PubMed search using the terms varenicline, akathisia, withdrawal, and discontinuation was conducted. No literature of this phenomenon was found; however, reports of other extrapyramidal symptoms were noted. Considering the timing of varenicline's discontinuation and its mechanism, a pharmacological link between its use and akathisia is possible. Akathisia is a severely uncomfortable sequela of medications that may produce severe outcomes, such as suicidal ideation. In this case, it is possible that the discontinuation of varenicline after 3 weeks of therapy led to akathisia, which was successfully treated with propranolol.
Prazosin initiation and dose titration in a patient with posttraumatic stress disorder on concurrent carvedilol
Authors: Khaw Chelsea , Argo Tami 
Published: September 2019

Abstract
One mechanism involved in the pathophysiology of posttraumatic stress disorder (PTSD) is increased noradrenergic stimulation. Prazosin, a commonly utilized treatment for PTSD nightmares, works to block noradrenergic stimulation of the alpha-1 adrenoreceptor. Dual antagonism of this receptor would be expected to increase risk of adverse effects. Carvedilol has both alpha-1 adrenergic and nonselective beta-adrenoreceptor antagonist activity. To our knowledge, there is no clinical guidance on use of prazosin in patients concomitantly prescribed carvedilol for hypertension. This case describes the successful titration of prazosin for PTSD symptoms in a 49-year-old male concurrently prescribed carvedilol for hypertension. This patient had a previous unsuccessful prazosin trial due to adverse effects. His second trial of prazosin was efficacious and well tolerated using individualized titration with close monitoring by mental health clinical pharmacy specialists in the pharmacist-managed prazosin titration clinic. This case details the importance of utilizing caution and close follow-up in prazosin dose titration in patients prescribed concomitant alpha-1 antagonists. This appears to be the first case report describing the successful dose titration of prazosin for PTSD in a patient on a concurrent alpha-1 antagonist antihypertensive agent.