bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Method to Form Smooth Films of Liquid Metal Supported by Elastomeric Substrate
Authors: Hirsch Arthur , Lacour Stéphanie P. 
Published: August 2018

AbstractSeveral methods are proposed to manipulate and pattern liquid metal films into elastic conductors but all lack precise control over the film thickness and roughness, thereby limiting its uniformity, stability, and reproducibility. Here, an approach relying solely on wetting phenomena is proposed to produce smooth film of liquid gallium (Ga) on extended surface areas with controlled thickness and electrical properties. The surface chemistry and topography of silicone rubber (poly(dimethylsiloxane)) is engineered with microstructured pillars and gold precoating layer to produce Ga superlyophilic substrates. Physical vapor deposition of Ga on such substrates leads to the formation of smooth and homogeneous films by imbibition of the surface topography rather than coalescence and formation of Ga drops. By capillarity, Ga accumulates in between the pillars up to their top surface, forming a smooth film with a root mean square roughness (Rq) smaller than 100 nm. The wetting conditions and electromechanical properties of the resulting films are compared based on the selection of the microtexture patterns and a model of the film sheet resistance as a function of the texture geometrical parameters is established.
Large‐Scale Conductive Yarns Based on Twistable Korean Traditional Paper (Hanji) for Supercapacitor Applications: Toward High‐Performance Paper Supercapacitors
Authors: Heo Young‐Jung , Lee Ji Won , Son Yeong‐Rae , Lee Jong‐Hoon , Yeo Chang Su , Lam Tran Dai , Park Sang Yoon , Park Soo‐Jin , Sinh Le Hoang , Shin Min Kyoon 
Published: August 2018

AbstractA simple and scalable method to fabricate a yarn‐type supercapacitor with a large specific capacitance without the aid of traditional pseudocapacitive electrode materials such as conducting polymers and metal oxides is reported. The yarn‐type supercapacitors are made from twisting reduced graphene oxide (rGO) or/and single‐walled carbon nanotubes (SWNTs)‐coated Korean traditional paper (KTP). The yarn‐type paper supercapacitor displays surprisingly enhanced electrochemical capacitance values, showing synergistic effect between rGO and SWNTs (500 times larger than performance of yarn‐type rGO‐coated paper supercapacitors). Coating rGO or/and SWNTs on KTP gives good morphology to the composite film, in which porosity increases and mean pore diameter decreases. The yarn‐type rGO/SWNT paper supercapacitor shows good mechanical strength, high flexibility, excellent electrochemical performance, and long‐life operation. The yarn‐type supercapacitor has an excellent electrochemical performance with a specific capacitance of 366 F g−1 at scan rate of 25 mV s−1 and high stability without any degradation in electrical performance up to 10 000 charge–discharge cycles. The average capacitance of rGO/SWNT@KTP yarn‐type supercapacitors is seven times higher than that of sheet‐type supercapacitors at scan rate of 500 mV s−1. The lighting of a red light‐emitting diode (LED) is demonstrated by the yarn‐type paper supercapacitor without connecting supercapacitors in series.
Incorporating fossils into the Pinaceae tree of life
Authors: Gernandt David S. , Reséndiz Arias Cecelic , Terrazas Teresa , Aguirre Dugua Xitlali , Willyard Ann 
Published: August 2018

Premise of the StudyPinaceae have a rich but enigmatic early fossil record, much of which is represented by permineralized seed cones. Our incomplete knowledge of morphology and anatomy in living and extinct species poses an important barrier to understanding their phylogenetic relationships and timing of diversification.MethodsWe expanded a morphology matrix to 46 fossil and 31 extant Pinaceae species, mainly adding characters from stem and leaf anatomy and seed cones. Using parsimony and Bayesian inference, we compared phylogenetic relationships for extant taxa with and without fossils from the morphology matrix combined with an alignment of plastid gene sequences.Key ResultsCombined analysis of morphological and molecular characters resulted in a phylogeny of extant Pinaceae that was robust at all nodes except those relating to the interrelationships ofPinus,Picea, andCathayaand the position ofCedrus. Simultaneous analysis of all fossil and extant species did not result in changes in the relationships among the extant species but did greatly reduce branch support. We found that the placement of most fossils was sensitive to the method of phylogenetic reconstruction when analyzing them singly with the extant species.ConclusionsA robust phylogenetic hypothesis for the main lineages of Pinaceae is emerging. Most Early Cretaceous fossils are stem or crown lineages ofPinus, but close relationships also were found between fossils and several other extant genera. The phylogenetic position of fossils broadly supports the existence of extant genera in the Lower Cretaceous.
Silver‐Catalyzed Decarboxylative Trifluoromethylthiolation of Cinnamic Acids: An Easy Access to α‐Trifluoromethylthiolated Ketones
Authors: Sharma Anup Kumar , Yadav Arvind Kumar , Singh Krishna Nand 
Published: August 2018

AbstractA silver‐catalyzed decarboxylative difunctionalization of cinnamic acids has been developed to afford a variety of α‐trifluoromethylthiolated ketones under mild reaction conditions using in situ generated SCF3 source by the combination of Langlois’ reagent and CS2.
Preparation and characterization of antimicrobial, biodegradable, triclosan‐incorporated polyhydroxybutyrate‐co‐valerate films for packaging applications
Authors: Sabharwal Prabhjot Kaur , Chattopadhyay Sruti , Singh Harpal 
Published: August 2018

ABSTRACTThe prospective application of polyhydroxybutyrate‐co‐valerate (PHB‐VA) as a biodegradable polymer for packaging through the incorporation of triclosan (TCS) was studied via thermal, mechanical, and antimicrobial studies. The solvent‐casting technique was used for the preparation of PHB‐VA–TCS blend films. The blend films were characterized by differential scanning calorimetry, thermogravimetry, Fourier transform infrared spectroscopy, and mechanical properties measurements. The addition of TCS to PHB‐VA resulted in increased film stretchability along with improved flexibility. The crystallization and melting temperatures of PHB‐VA decreased with increasing concentration of TCS. Scanning electron microscopy images showed a homogeneous dispersion of TCS in PHB‐VA. The bactericidal activities of the PHB‐VA–TCS blend films were investigated against Escherichia coli and Staphylococcus aureus by the disc‐diffusion method. The blend films exhibited higher antibacterial activities with increasing concentration of TCS. We concluded from the study that TCS could be successfully incorporated into PHB‐VA to obtain flexible antimicrobial films for packaging applications. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018, 135, 46862.
Use of super absorbent hydrogels derivative from acrylamide with itaconic acid and itaconates to remove metal ions from aqueous solutions
Authors: El‐Halah Amal , Machado Daniel , González Nain , Contreras Jesús , López‐Carrasquero Francisco 
Published: August 2018

ABSTRACTPoly(acrylamide‐co‐itaconic acid) (AAm/IA) and poly(acrylamide‐co‐monomethoxyethyl itaconate) (AAm/MEI) hydrogels (HGs) synthesized at different molar ratios were used to study the adsorption of some metal ions as Cu2+, Ni2+, Pb2+, Cd2+, and Fe3+ in aqueous solutions at different concentration: 10, 50, 100, 500, and 1000 mg L−1. Statistical analysis was performed and the effect of the metal ion, ion concentration, and hydrogel (HG) composition, on adsorption and adsorption efficiency, was evaluated for both HGs studied (AAm/IA and AAm/MEI) and each factor gave rise to significant differences (P ≤ 0.05). The adsorption depends on the type of ion, its concentration, and also influenced by the type and composition of the HGs. For each system the adsorption efficiencies for all ions were similar with exception of Fe3+, which showed the highest adsorption efficiency in AAm/MEI HG, but the less for the AAm/IA. For both systems, the maximum adsorption efficiency was observed when the molar ratio AAm/IA or AAm/MEI is 80/20. When the adsorption was carried out with individual ions, AAm/MEI HG was more efficient than AAm/IA. For a multielement sample of Cu2+, Ni2+, Pb2+, and Cd2+, both HGs could adsorb all the ions and their behavioral trend was the same in both cases, in which the adsorption efficiency was Pb2+ > Cu2+ > Cd2+ > Ni2+. The results of the statistical analysis evidence the advantage of its use in this type of studies. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 46999
Coastal occupation before the “Big Swamp”: Results from excavations at John Wayne Country Rockshelter on Barrow Island
Authors: DITCHFIELD KANE , MANNE TIINA , HOOK FIONA , WARD INGRID , VETH PETER 
Published: August 2018

ABSTRACTIn this paper, we present a terminal Pleistocene/early Holocene archaeological record from John Wayne Country Rockshelter (JWCR), located on Barrow Island in north‐western Australia. The rock shelter was used between 15000 and 7000 calBP, and provides insights into how Aboriginal people interacted with a changing coastal landscape throughout postglacial sea‐level rise. The faunal record reflects this fluctuating local landscape. The late Pleistocene faunal assemblage largely consists of arid plains terrestrial fauna, and then transitions to a diverse marine invertebrate taxa midden. This record demonstrates coastal resource use throughout the terminal Pleistocene, before the expansion of mangrove forests across northern Australia. The stone artefact assemblages indicate varied expedient reduction patterns. The assemblages include artefacts manufactured from local limestone and non‐local sources. Our analyses indicate that occupation durations at JWCR were longer during the late Pleistocene compared to the early Holocene, when productive mangrove environments became proximal. The implications of these results are twofold. First, effective use of coastal plain environments was probably just as important for coastal occupation as marine resource procurement. Second, the presence of relatively dense marine faunal assemblages is not necessarily a reliable proxy for individual coastal‐site occupational intensity under conditions of local resource productivity.
Organic Mechanoluminescence with Aggregation‐Induced Emission
Authors: Ubba Eethamukkala , Tao Yu , Yang Zhiyong , Zhao Juan , Wang Leyu , Chi Zhenguo 
Published: August 2018

AbstractMechanoluminescence (ML) involves the emission of light from various organic and inorganic materials upon mechanical stimulus. In this review, we contemplate the advances of metal‐free, purely organic ML compounds with aggregation‐induced emission (AIE), which give strong emission upon mechanical force. We show the new ML‐AIE based materials can be used explore the basic of ML properties with structure–property relationships and molecular interactions. The flourishing idea of ML‐AIE may help to find the characteristic and elusive component of ML as it partners with AIE, which upgrades the emission property in solids or aggregates. Recent advances in ML‐AIE information could increase the wide scope of research in this expanding area, as these materials have promising applications in different optoelectronic areas.
Tug‐of‐War in a Dynamic Helical Peptide: Solvent‐Induced Helix‐Helix Transition of a Lactam‐Bridged Peptide Composed of Point‐ and Axial Chiralities Remote from Each Other
Authors: Urushima Akio , Ousaka Naoki , Yashima Eiji 
Published: August 2018

AbstractThe dynamic axial chirality of oligopeptide‐bound 2,2′‐bipyridine (bpy) residues can be remote‐controlled and diastereoselectively locked. A right‐handed (P)‐310‐helix is first induced in the dynamic helical oligopeptide by an l‐valine (l‐Val) far from the bpy moiety and the induced axial bpy chirality is diastereoselectively dioxidized. The resulting l‐Val‐containing linear oligopeptides at the 3,3′‐positions retain their (P)‐310‐helices independent of the axial chirality (aR or aS) of the N‐terminal N,N′‐dioxide‐bpy unit, while a lactam‐bridged dynamic helical oligopeptide exhibits a unique solvent‐induced helix‐helix transition as a result of competitive helix‐inducing biases between the l‐Val and (aR) or (aS)‐N,N′‐dioxide‐bpy residues remote from each other along the entire oligopeptide chain in a tug‐of‐war like manner.
Family history of immune conditions and autism spectrum and developmental disorders: Findings from the study to explore early development
Authors: Croen Lisa A. , Qian Yinge , Ashwood Paul , Daniels Julie L , Fallin Daniele , Schendel Diana , Schieve Laura A. , Singer Alison B. , Zerbo Ousseny 
Published: August 2018

Numerous studies have reported immune system disturbances in individuals with autism and their family members; however, there is considerable variability in findings with respect to the specific immune conditions involved, their timing, and the family members affected and little understanding of variation by autism subphenotype. Using data from the Study to Explore Early Development (SEED), a multi‐site case‐control study of children born 2003–2006 in the United States, we examined the role of family history of autoimmune diseases, asthma, and allergies in autism spectrum disorder (ASD) as well as other developmental disorders (DD). We investigated maternal immune conditions during the pregnancy period, as well as lifetime history of these conditions in several family members (mother, father, siblings, and study child). Logistic regression analyses included 663 children with ASD, 984 children with DD, and 915 controls ascertained from the general population (POP). Maternal history of eczema/psoriasis and asthma was associated with a 20%–40% increased odds of both ASD and DD. Risk estimates varied by specific ASD subphenotypes in association with these exposures. In addition, children with ASD were more likely to have a history of psoriasis/eczema or allergies than POP controls. No association was observed for paternal history or family history of these immune conditions for either ASD or DD. These data support a link between maternal and child immune conditions and adverse neurodevelopmental outcomes, and further suggest that associations may differ by ASD phenotype of the child. Autism Research 2019, 12: 123–135. © 2018 International Society for Autism Research, Wiley Periodicals, Inc.Lay SummaryUsing data from a large multi‐site study in the US—the Study to Explore Early Development—we found that women with a history of eczema/psoriasis and asthma are more likely to have children with ASD or DD. In addition, children with ASD are more likely to have a history of psoriasis/eczema or allergies than typically developing children. These data support a link between maternal and child immune conditions and adverse neurodevelopmental outcomes.
Life cycle assessment calculative practices in the Swedish biofuel sector: Governing biofuel sustainability by standards and numbers
Authors: Lazarevic David , Martin Michael 
Published: August 2018

AbstractSince the introduction of the European Union's Renewable Energy Directive (RED), biofuel‐producing firms are required to perform life cycle assessment (LCA) based greenhouse gas accounting in order to fulfill part of directive's sustainability criteria. This paper adopts the concepts of “governing by standards” and “governing by numbers” to understand the LCA practices of biofuel‐producing firms and assess the critical moments of friction between these alternative modes of governance. We focus our analysis on the use of LCA in the Swedish biofuel industry, undertaking case studies on the use of LCA in four Swedish biofuel‐producing firms and semistructured interviews with industry associations and governmental bodies. Results indicated that the RED not only influences what biofuel sustainability entails but also structures the calculative practices used to measure it. At the same time, our results point to friction between achieving regulatory compliance and improving biofuel sustainability.
ING5‐mediated antineuroblastoma effects of suberoylanilide hydroxamic acid
Authors: Wu Ji‐cheng , Jiang Hua‐mao , Yang Xiang‐hong , Zheng Hua‐chuan 
Published: August 2018

AbstractNeuroblastoma is the most common extracranial solid neuroendocrine cancer and is one of the leading causes of death in children. To improve clinical outcomes and prognosis, discovering new promising drugs and targeted medicine is essential. We found that applying Suberoylanilide hydroxamic acid (SAHA; Vorinostat, a histone deacetylase inhibitor) and MG132 (a proteasome inhibitor) to SH‐SY5Y cells synergistically suppressed proliferation, glucose metabolism, migration, and invasion and induced apoptosis and cell cycle arrest. These effects occurred both concentration and time dependently and were associated with the effects observed with inhibitor of growth 5 (ING5) overexpression. SAHA and MG132 treatment increased the expression levels of ING5, PTEN, p53, Caspase‐3, Bax, p21, and p27 but decreased the expression levels of 14‐3‐3, MMP‐2, MMP‐9, ADFP, Nanog, c‐myc, CyclinD1, CyclinB1, and Cdc25c concentration dependently, similar to ING5. SAHA may downregulate miR‐543 and miR‐196‐b expression to enhance the translation of ING5 protein, which promotes acetylation of histones H3 and H4. All three proteins (ING5 and acetylated histones H3 and H4) were recruited to the promoters of c‐myc, Nanog, CyclinD1, p21, and p27 for complex formation, thereby regulating the mRNA expression of downstream genes. ING5 overexpression and SAHA and/or MG132 administration inhibited tumor growth in SH‐SY5Y cells by suppressing proliferation and inducing apoptosis. The expression of acetylated histones H3 and ING5 may be closely linked to the tumor size of neuroblastomas. In summary, SAHA and/or MG132 can synergistically suppress the malignant phenotypes of neuroblastoma cells through the miRNA‐ING5‐histone acetylation axis and via proteasomal degradation, respectively. Therefore, the two drugs may serve as potential treatments for neuroblastoma.
Long noncoding RNA MALAT1 regulates HDAC4‐mediated proliferation and apoptosis via decoying of miR‐140‐5p in osteosarcoma cells
Authors: Sun Yuxiu , Qin Baoli 
Published: August 2018

AbstractNoncoding RNAs regulate the initiation and progression of osteosarcoma (OS). The role of long noncoding RNA metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) playing in OS and whether the function it working out was achieved through HDAC4 pathway remain uncovered. In this study, we illustrated that MALAT1 was upregulated and was correlated with poor prognosis in OS patients. Meanwhile, we demonstrated that a depression of MALAT1 suppressed proliferation and promoted apoptosis in OS cell line HOS and 143B. Further, we verified that MALAT1 exerting its function via upregulating of histone deacetylase 4 (HDAC4). Through an online prediction, a series of luciferase assays and RNA pull‐down assays, we demonstrated that both MALAT1 and HDAC4 were the targets of microRNA‐140‐5p (miR‐140‐5p) via sharing a similar microRNA responding elements. Even further, we revealed that MALAT1 served as a ceRNA of HDAC4 via decoying of miR‐140‐5p. Finally, we proved that MALAT1 promoted OS tumor growth in an in vivo animal study. In summary, the outcomes of this study demonstrated the complex ceRNA network among MALAT, miR‐140‐5p, and HDAC4‐mediated proliferation and apoptosis in OS. This study might provide a new axial in molecular treatment of OS.
Circulating monocytes from prostate cancer patients promote invasion and motility of epithelial cells
Authors: Cavassani Karen A. , Meza Rebecca J. , Habiel David M. , Chen Jie‐Fu , Montes Alexander , Tripathi Manisha , Martins Gislâine A. , Crother Timothy R. , You Sungyong , Hogaboam Cory M. , Bhowmick Neil , Posadas Edwin M. 
Published: August 2018

AbstractBackgroundRecruited myeloid cells are known to promote cancer initiation, malignant progression, metastasis, and resistance to therapy in the tumor niche. We tested the hypothesis that circulating blood monocytes from advanced prostate cancer (PCa) patients exhibit a protumor phenotype and directly influence the tumor microenvironment in response to tumor‐derived signals.MethodsBlood monocytes from advanced and stable PCa patients were cultured, and the conditioned media (CM) were collected and analyzed using standard invasion and wound closure assays to measure effects on invasion and motility of PCa tumor cells. We then identified the proteome profile of these monocytes using proteome array and ELISA.ResultsConditioned media from circulating monocytes in patients with metastatic prostate cancer (PCa‐M) increased invasion of epithelial PCa cells in vitro. Proteome Profiler Analysis revealed that monocyte‐derived CM from metastatic castration‐resistant (mCRPC) patients presented high levels of chitinase‐3‐like 1 (CHI3L1, YKL‐40) when compared to patients with stable disease (PCa‐N) and healthy control individuals (HC). The only described receptor for CHI3L1, interleukin‐13 receptor α2 (IL‐13Rα2), was significantly up‐regulated in the human metastatic PCa cell line, ARCaPM. Accordingly, we observed that the activation of IL‐13Rα2 from PCa‐M CM increased the invasiveness of ARCaPM cells while siRNA directed against this receptor significantly reduced invasiveness of these cells in the presence of CM from PCa‐M patients.ConclusionsThus, we show that circulating monocytes from metastatic PCa patients exert a tumor‐promoting role via the secretion of CHI3L1, and CHI3L1 demands further exploration as a possible therapeutic target in advanced PCa.
miR‐370 promotes high glucose‐induced podocyte injuries by inhibiting angiotensin II type 1 receptor‐associated protein
Authors: Xian Yuxin , Dong Liping , Jia Yong , Lin Yi , Jiao Wenjuan , Wang Yao 
Published: August 2018

AbstractmiRNAs expression profiles in podocyte injuries have been reported in different models in vivo and in vitro. In the present study, miR‐370 was elevated in high glucose‐stimulated podocyte, and the post‐transcriptional mechanism of miR‐370 was investigated in high glucose‐induced podocyte injuries. The gene and protein levels were assayed by RT‐qPCR and Western blotting, respectively. Annexin V‐fluorescein isothiocyanate (FITC)/propidium iodide (PI) staining was used to evaluate the apoptosis in high glucose‐stimulated podocyte. The targeted genes were predicted by a bioinformatics algorithm and confirmed by a dual luciferase reporter assay. The results demonstrated that over‐activation of miR‐370 was verified in high glucose‐treated podocytes, while miR‐370 repression protected against high glucose‐induced apoptosis, cell membrane, and DNA damage in podocytes. We also found that AGTRAP as a direct target of miR‐370 served as an opposite effect to miR‐370, and overexpression of AGTRAP blocked high glucose‐induced podocytes dysfunction. In conclusions, high glucose‐induced podocytes damage by activating miR‐370 signaling targeted to inhibit the expression of AGTRAP, representing a novel and promising therapeutic target for the treatment of DN.