bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-Term Benefits and Safety of Statins in Patients with Kidney Failure
Authors: Cheng Franco Wing Tak , Xu Wanchun , Tang Sydney Chi Wai , Wan Eric Yuk Fai 
Published: October 2024

Key Points

Patients with kidney failure are at a higher risk of cardiovascular diseases, but the evidence for statin therapy remains inconclusive.The long-term benefits and risks of statin therapy in patients with kidney failure were analyzed using public electronic health records in Hong Kong.Statin therapy was associated with a lower risk of major cardiovascular diseases and all-cause mortality without a higher risk of major adverse events.

Background
Patients with kidney failure are at elevated risk of cardiovascular diseases. Although statins are commonly used to mitigate cardiovascular risk among the population with high risk, the evidence for initiating statin therapy among patients with kidney failure remains inconclusive. This study aimed to investigate the long-term benefits and risks associated with statin therapy in patients with kidney failure.

Methods
Using territory-wide public electronic health records in Hong Kong, 3019 statin-eligible individuals with kidney failure and elevated LDL cholesterol ≥100 mg/dl from January 2008 to December 2015 were included for analysis. The framework of target trial emulation was adopted to investigate the risk of the major cardiovascular diseases (i.e., a composite of myocardial infarction, heart failure, and stroke), all-cause mortality, and major adverse events (i.e., myopathies and liver dysfunction) between statin initiators and statin noninitiators. The pooled logistic model was used to obtain the hazard ratio for the outcomes of interest in both intention-to-treat (ITT) analysis and per-protocol (PP) analysis.

Results
Significant risk reduction associated with statin therapy (hazard ratio [95% confidence interval]) was observed for major cardiovascular diseases (ITT: 0.78 [0.62 to 0.98]; PP: 0.66 [0.50 to 0.87]) and all-cause mortality (ITT: 0.80 [0.68 to 0.95]; PP: 0.60 [0.48 to 0.76]). The standardized 5- and 10-year absolute risk reduction in PP analysis was 7% (3% to 11%) and 11% (4% to 18%), respectively. No significant risks for the major adverse events were observed.

Conclusions
Statin therapy was associated with lower risks of cardiovascular diseases and all-cause mortality in patients with kidney failure without a higher risk of major adverse events.
Hume and the Labor Theory of Value
Authors: Schabas Margaret 
Published: October 2024

The received view does not associate David Hume with the genesis of the labor theory of value, but as is argued here, Hume issued a number of key propositions that belong to the labor theory of value such that he rightly belongs to the classical school of political economy. Hume articulated both the analytic claim, that labor is the primary determinant of exchange-value and hence the price, and the explanatory claim, that a price could be reduced down to the labor embodied in its production. His attention, however, was directed more to the quality than the quantity of labor and in that respect there was no direct correlation between the temporal units of labor and the price. Insofar as wages and profits are inversely related, or so he argued, the falling rate of profit over the past century meant that wages had become the primary factor in determing a price. Furthermore, Hume treated capital goods as stored labor, and put much weight on the role of the new work ethic and the growth of artisanal production which had contributed, in part, to the unprecedented wealth of Western Europe. Hume also recommended that the state adopt policies to improve the mobility and supply of labor, and promote a healthier and happier population.
CAMINHOS DO SUS: AMPLIAÇÃO DE UMA TECNOLOGIA SOCIAL PARA ENFRENTAMENTO DAS INIQUIDADES EM SAÚDE
Authors: Royer Perini Isabella , Fabiana Dreissig Jodéli , Weber de Vargas André , Niandra da Silva Kayla , Da Silva Pedroso Carolina , De Souza Machado Letiane , Linhares Garcia Edna 
Published: October 2024

Este artigo trata do trabalho de ampliação do jogo de tabuleiro “Caminhos do SUS”, uma tecnologia social didática produzida pelo Grupo da Pesquisa sobre Adolescências (GRUPAD), da Universidade de Santa Cruz do Sul (UNISC), que visa promover educação popular em saúde com adolescentes escolares. De caráter descritivo, tem como objetivo apresentar o processo de construção de novas cartas no jogo, cujas temáticas são: racismo, pessoa com deficiência, LGBTQIAPN+fobia e bullying. A necessidade de ampliação foi reconhecida a partir de uma atividade de brainstorming com os aplicadores do jogo, na qual surgiu o entendimento da relevância do debate destas temáticas, tão implicadas e atreladas às vivências dos jovens. A primeira carta relata uma situação corriqueira de racismo em ambiente escolar, produtora de prejuízos psicossociais. Na segunda, o tema da pessoa com deficiência compreende as vivências de um sujeito cada vez mais presente em nossa sociedade, que merece inclusão e acolhimento: o autista. Na carta sobre LGBTQIAPN+fobia é refletido sobre um caso de violência que é comum, oriundo de discriminações e preconceitos a essa população segregada e marginalizada. Por último é retratado um caso de bullying escolar, problemática presente entre adolescentes, a qual é produtora de sofrimentos. As narrativas inseridas são articuladas com os serviços de saúde do território, visando compartilhar conhecimento quanto ao funcionamento destes, em relação a essas temáticas.
Effects of the 2022 Mw 7.0 Chihshang Earthquake on the Shallow Creeping of the Central Longitudinal Valley Fault in Eastern Taiwan: Insights from Precise Leveling Measurements
Authors: Murase Masayuki , Matta Nobuhisa , Ishiyama Tatsuya , Lin Cheng-Horng , Chen Wenshan , Yen Jiun-Yee , Shyu J. Bruce H. , Lin Juijen , Nishikawa Yuka , Yen I-Chin , Widiatmoko Fajar Rizki 
Published: October 2024

Abstract
This study investigated the effects of the 2022 Mw 7.0 Chihshang earthquake in eastern Taiwan on the shallow creeping of the central Longitudinal Valley fault (LVF). Precise leveling surveys were conducted along the Ruisui-Dewu, Yuli, and Dongzhu routes over the LVF. Before the earthquake, previous leveling surveys had detected deformations caused by stable fault creeping of the LVF. Interseismic linear trends and coseismic deformations were removed from the leveling data. Two shallow faults at 1 km were estimated from the corrected-coseismic deformation for the Yuli route. A shallow fault at 1 km and a deep fault at 5 km were estimated from the interseismic deformation. A positive delta Coulomb failure function change was calculated for shallow faults due to the creeping movement on the deep fault before the earthquake, and the creeping movement on the deep fault before the earthquake may have promoted the rupture of the shallow fault. The strong Chihshang earthquake most likely triggered the rupture of the shallow fault, on which strain had been concentrated by the interseismic creeping of the deeper fault. In contrast, the accumulated total strain at the deeper part might be quite low due to a strain release process for a steady creeping movement on deep fault in the interseismic period. The significant slip was not induced in the coseismic period. Although significant slip occurred in the shallower part, the slip might not be induced in the deeper part adjacent to the asperity of the LVF. In the Dewu route, the observed large west-side-uplift is attributed to the coseismic rupture of the Chihshang earthquake. In the Dongzhu route, an interseismic east-side-uplift by a creeping fault and a coseismic west-side-uplift were observed at the same location, indicating a local tensile stress field by the Chihshang earthquake.
“Perplexing” cough
Authors: Ponomareva I. B. , Glotov S. I. , Uryasev O. M. , Berstneva S. V. , Lunyakov V. A. 
Published: October 2024

Cough is a serious problem of practical pulmonology. The mechanisms of cough occurrence are diverse and numerous diseases are associated with chronic cough syndrome. The diagnosis can be challenging because of a “perplexing”, “unexplained”, or “idiopathic” cough.The aim of the review was to consider the main underlying mechanisms of the “perplexing” cough, its potential course, an algorithm for managing patients with the persistent cough, and new treatment methods.Conclusion. Chronic “perplexing” cough disrupts the patient’s quality of life and reduces their performance. Unveiling the mechanisms of its development may increase the treatment efficacy.
Feira de Ciências como estratégia para a implementação da Aprendizagem Baseada em Projetos
Authors: Da Silva Borges Frederico , Rodrigues Martins dos Reis Fernando 
Published: October 2024

A educação tem um papel social a cumprir. A legislação em vigor afirma que ela deve ser responsável por formar pessoas aptas para exercer sua cidadania de maneira plena. O ensino exclusivamente transmissivo tem sido alvo de críticas pelo seu pequeno poder de relacionar os objetos de conhecimento com as habilidades necessárias para a vida e apontado como um dos responsáveis pelo baixo interesse pela educação. A Aprendizagem Baseada em Projetos é uma metodologia capaz de fortalecer habilidades que são necessárias para que os estudantes possam atuar no mundo de maneira eficaz, contribuindo para objetivos locais e globais. Este trabalho propõe apresentar um relato de experiência sobre a realização de uma feira de ciências, como evento para culminância de trabalhos escolares usando a Aprendizagem Baseada em Projetos. Essa feira foi realizada em uma cidade do interior do estado do Espírito Santo, e envolveu alunos que cursam os anos finais do ensino fundamental e alunos do ensino médio do município de realização, bem como de cidades próximas.
Development and Characterization of Advanced Nano-Coating with CeO₂, Al₂O₃, ZnO, and TiO₂ Nanoparticles for Enhanced Durability and Corrosion Resistance
Authors: SERROUNE Shad Abdelmoumen , UGM Dr. Khasani , Kakiecwski James , Brenton Marshall , SERROUNE5 Abdellatif , Basset Deborah , SERROUNE Hicham , Gescot Sebastien 
Published: October 2024

This study introduces an innovative sol-gel nano-coating designed to address silica scaling and corrosion in hydrothermal and high-stimulation environments. By incorporating CeO₂, Al₂O₃, ZnO, and TiO₂ nanoparticles into a polymer matrix through precise sonication techniques, the coating achieves uniform dispersion and enhanced functional performance.

The meticulous characterization of nanoparticle integration optimizes mechanical strength, thermal stability, and chemical resistance. Applied via a directional supplying device, the nano-coating is mechanically deposited onto the cemented walls of wells, providing robust protection against scaling and corrosion across diverse conditions, including varying temperatures and pH levels. Laboratory testing demonstrates significant reductions in silica scaling and corrosion rates, confirming the coating's efficacy in maintaining production efficiency in both hydrothermal projects and fracking operations.

This paper details the synthesis process and molecular chemistry involved in nanoparticle integration, alongside the resultant structural properties of the coating. Thermogravimetric analysis (TGA) assesses thermal stability, while kinetic models such as Flynn-Wall-Ozawa (FWO) and Kissinger-Akahira-Sunose (KAS) evaluate activation energy without assuming specific reaction models. The findings highlight the potential of this advanced nano-coating as a robust solution for enhancing operational longevity and efficiency in challenging industrial applications.
Wdrażanie innowacji społecznych przez wiejskie organizacje pozarządowe i lokalne grupy działania
Authors: Zajda Katarzyna 
Published: October 2024

Problematyka wdrażania innowacji społecznych wzbudza zainteresowanie badaczy i praktyków z całego świata. W Polsce jest podejmowana rzadko, zwłaszcza w kontekście specyfiki wsi i podmiotów ważnych dla rozwiązywania problemów społecznych jej mieszkańców, to jest organizacji pozarządowych oraz lokalnych grup działania.
Przedmiotem rozważań w monografii uczyniono ich aktywność na rzecz wdrażania innowacji społecznych definiowanych jako zmiany w obszarze rozwiązywania problemów społecznych polegające na powstawaniu nietypowych praktyk społecznych, alternatywnych w stosunku do dominujących na danym obszarze (tj. na obszarze gminy wiejskiej lub partnerstwa terytorialnego).
Celem analizy było po pierwsze określenie specyfiki innowacji społecznych wdrażanych w gminach wiejskich przez organizacje pozarządowe oraz lokalne grupy działania. Po drugie, zidentyfikowanie stymulatorów ich wdrażania spośród zmiennych takich jak: współpraca z różnymi podmiotami lokalnymi i tymi, które posiadały swoje siedziby poza obszarem danej gminy wiejskiej (lub partnerstwa terytorialnego) oraz włączanie mieszkańców w rozwiązywanie dotykających ich problemów społecznych. W przypadku organizacji pozarządowych do potencjalnych stymulatorów wdrażania innowacji społecznych zaliczono również długość ich działania, poziom społecznej profesjonalizacji i ekonomizacji oraz profil działalności.
W celu uzyskania odpowiedzi na postawione pytania badawcze przeprowadzono badanie jakościowe i ilościowe. Wykorzystano metodę zbiorowego studium przypadku oraz metodę sondażową.
Rezultaty badania stały się podstawą do sformułowania wniosków dotyczących specyfiki wdrażania innowacji społecznych przez wiejskie organizacje pozarządowe oraz lokalne grupy działania, jak również rekomendacji dotyczących stymulowania tego procesu.

Publikacja powstała w ramach projektu pt.: „Lokalne systemy innowacji społecznych na wsi” (nr rejestracyjny 015/19/D/HS6/00690) finansowanego przez Narodowe Centrum Nauki (na podstawie umowy: UMO-2015/19/D/HS6/00690)
Complex assessment of ambient particulate matter in a small settlement with coal-handling port
Authors: Kholodov Aleksei S. , Kirichenko Konstantin Yu. , Vakhniuk Igor A. , Duan Piaopiao , Golokhvast Kirill S. 
Published: October 2024

Relevance. Russian coal exports have been steadily increasing in recent years, and Far Eastern ports, originally not adapted to dusty cargoes, have switched to coal operations. Unoptimized coal handling leads to increased content of coal-containing particles in the air and to various environmental problems. Aim. To analyze the concentration of particulate matter in the air and the chemical composition of particles on the surface of conifer needles in the Posyet settlement (Primorsky Krai, Russia), where a large coal terminal operates. Materials and methods. The chemical composition was studied on the surface of conifer needles by X-ray fluorescence and in washout of conifer needle samples using Raman spectroscopy and energy dispersive analysis. Concentrations of particles with the diameter of 2.5 and 10 μm (PM2.5 and PM10, respectively) were measured using automatic monitoring stations. Results and conclusions. Chemical composition was dominated by mineral particles (calcite, silicates, etc.). However, the presence of coal particles (up to 8.3%) and metal particles was also observed. Mean concentrations of PM2.5 and PM10 were within the Russian and international health standards, but close to their upper limits. Concentrations of both measured particle fractions were highest during the winter months (as well as in March, which is traditionally a cold month in the Far East), followed by a gradual decrease. The study obtained new data on the annual variations of concentrations of PM2.5 and PM10, as well as on the basic composition of particles from the surface of woody vegetation (needles) as an indicator of the state of air pollution in this settlement.
Numerical simulation of the stress-strain state near the injection well at deep disposal facilities for liquid radioactive waste
Authors: Popov Sergey N. , Kokorev Oleg N. , Zavedy Taras Yu. , Manevich Alexander I. 
Published: October 2024

Relevance. The need to predict deformations of the earth's surface near injection wells pumping liquid radioactive waste, as well as their stability when pressure changes in the well during injection. Aim. To perform a numerical analysis of the stress-strain state of the structural elements of the injection well and the surrounding rock mass using the finite element method, to determine the magnitude of the deformations of the earth's surface and define the stability of the well and the strength of the cement stone at the maximum injection pressure of liquid radioactive waste. Objects. Near-wellbore zone of one of the injection wells located at the liquid radioactive waste injection site. Methods. Numerical finite element method for calculating the stress-strain state of the near-wellbore zone, taking into account the distribution of the elastic properties of rocks along the simulated section and the main structural elements of the well. Results. The authors have developed the numerical finite element scheme of one of the injection wells, taking into account its main structural elements, as well as allowing you to set the pressure distribution within the exploited horizon during the injection of waste. In the model, the distribution of the elastic properties of rocks along the section was set, taking into account their lithological features. The authors carried out the analysis of the hydrodynamic parameters of the well operation and determined the maximum pressure at the wellhead during the injection of liquid radioactive waste, equal to 1.71 MPa. Numerical modeling of the stress-strain state of the near-wellbore zone was performed in two stages: for the conditions of an idle well and taking into account the pressure distribution at the maximum waste injection pressure. The distribution of vertical displacements at the level of the earth's surface, as well as at the top of the operational horizon at the maximum pressure of liquid radioactive waste injection, is obtained. It is shown that at such a pressure, the largest uplifts will be: on the earth's surface – 4.5 cm, on the top of the production horizon – 11 cm. An assessment of the stability of the well structural elements at a maximum waste injection depth of 280 m, corresponding to the maximum pressure, showed that the stresses in the well and cement stone are much lower than the values that can lead to their violation. For cement stone, the safety factor at a maximum pressure of 1.71 MPa was equal to 7.8.
Rehabilitation Impact of Vivifrail Exercise Program Type C on the Cognitive Function of Pre-Frail Elderly People in the Community
Authors: Sri Soenarti  , Dwi Indriani Lestari  , Muhammad Barlian Nugroho  , Harien Lestari  , Tita Hariyanti  
Published: October 2024

Highlights:1. This study emphasizes the importance of providing physical exercises to pre-frail elderly individuals, especially in a community setting.2. This study establishes a foundation for future research to explore the relationship between physical exercise, particularly the Vivifrail Type C Protocol, and cognitive function in pre-frail elderly individuals.

Abstract
Frailty is a clinical syndrome that increases vulnerability, potentially leading to disability or death. The pre-frail phase is ideal for preventing frailty and improving quality-adjusted life years, particularly through physical exercises that reduce the risk of dementia and cognitive impairment. Multicomponent exercises, such as the Vivifrail Exercise Program, may enhance cognitive function and daily independence by preventing and mitigating frailty through tailored routines. However, its impact on cognitive function in pre-frail elderly people had not been well studied. This study aimed to determine the effect of the Vivifrail Exercise Program Type C on the cognitive function of pre-frail elderly people. This study was a quasi-experiment with a non-randomized control group pretest-posttest design. The sample was chosen by the quota sampling method. Twenty-seven subjects were analyzed, comprising 16 individuals in the exercise group and 11 individuals in the control group. The exercise group participated in the Vivivfrail Type C Exercise Program, with 45-minute sessions conducted biweekly for 12 weeks. The evaluated parameters included the Montreal Cognitive Assessment-Indonesian Version (MoCA-INA) and the Loewenstein Occupational Therapy Cognitive Assessment (LOTCA). The statistical analysis utilized the Kruskal-Wallis test, followed by the post-hoc Mann-Whitney test and independent t-test (p<0.05). A path analysis was performed using simple linear regression. The subjects' average ages were 72.2 years in the control group and 67.47 years in the exercise group. The Vivifrail Exercises Program Type C significantly improved the MoCA-INA scores from 20.25 to 24.06. It also increased the LOTCA scores in several domains, i.e., thinking operations and visual perception. The exercise group demonstrated more improvement than the control group (p=0.032). An enhancement in cognitive function was particularly observed in elderly women with pre-frailty. In conclusion, the Vivifrail Exercise Program Type C can help improve the cognitive function of the elderly within the community.
Correction of a Golf Club Deformity of the Femur Using a Computer-Assisted Circular Ring Fixator
Authors: Goodwin Margaret A. , Moore Brady P. , Hagedorn John C. 
Published: October 2024

Case:
The golf club deformity is the most notable malreduction that occurs after distal femur fracture fixation. This can lead to disruption of the patient’s knee biomechanics, arthritis, and functional deterioration. There is a lack of consensus for optimal treatment of these malunions among the orthopaedic community. We present a technique that uses an osteotomy and ring external fixation with computer-assisted deformity correction and retrograde intramedullary nailing to secure correction.

Conclusion:
Our case shows a potential means to achieve a reliable and objective method of measuring, correcting, and securing the fixation of a golf club deformity.
Building a fully digital controller with Altera Cyclone FPGA and Nios Processor for Induction Heating application
Authors: Villamizar Jairo , Borra Vamsi , Li Frank 
Published: October 2024

Abstract

This paper presents the development of a fully digital controller designed for induction heating machines capable of delivering up to 50 kW across a frequency range up to 500 kHz. A critical feature of the controller is its ability to prevent operation within capacitive region, thereby safeguarding the integrity of the inverter. The control strategy employs a proportional-integral algorithm based on phase shift between voltage and current to regulate power by adjusting frequency. The phase shift calculation is achieved through successive subtractions performed at high speed. Performance evaluation was conducted by comparing the obtained phase shift with the setpoint. The implementation utilizes Intel Altera devices, ensuring robust performance and adaptability. Experimental results demonstrate the controller’s efficacy, achieving low errors within specified safety margins of operation. The proposed architecture can be adapted to implement control systems for different modulation techniques. This research contributes to advancing digital control solutions in high-frequency power electronics, offering scalability and versatility for industrial applications.