bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multivariate method to identify inequalities in oral healthcare access
Authors: Fonseca Emílio Prado Da 
Published: October 2018

ABSTRACT
Objective: The aim of this study is to apply a multivariate method for municipality's classification according access to oral health in adults. Materials and Methods: This is a cross-sectional epidemiological study. Were used multivariate classification called nonhierarchical cluster analysis K-means. The strategy brings together municipalities' similarity as access to oral health, where the most similar are next and the most different from getting further away. In addition, it allows reducing the intragroup variance and maximizing intergroup variance. It was assumed the number of four groups. Results: Among adults, 3,185 (52.63%) visited the dentist less than a year, and 357 (5.90%) have never been to the dentist. Homogeneous groups showed differences in the time since the last visit to the dentist for adults. The analysis of variance by the F statistic rejected the hypothesis that the variances are equal for the variables related to the time since the last visit to the dentist. Conclusion: It was possible to identify the inequalities in the access to oral healthcare services for adults and locate spatially municipalities whose subjects take longer to visit the dentist.
First dental visit: Age, reason, and experiences of Saudi children
Authors: Alshahrani Nourah Falah , Alshahrani Ayesha Nasser A , Alahmari Maram Awdah , Almanie Asrar Mohammed , Alosbi Abrar Mohammed , Togoo Rafi A 
Published: October 2018

ABSTRACT
Objective: A study was conducted among parents/guardians of children attending the Outpatient Department of King Khalid University College of Dentistry, Abha, to assess the attitude and knowledge regarding children's first dental visit and related aspects. Materials and Methods: A cross-sectional questionnaire-based study was conducted among a convenient sample of 320 parents/guardians. All the parents/guardians willing to participate in the study and whose children visiting the dentist for the first time were included in the study. Children's behavior was assessed using Frankl's scale. Results: Majority (29%) of the children visited the dentist for the first time at the age of 3–6 years, while the least percentage (8%) visited the dentist for the first time at the age of 0–1 year. A statistically significant difference was found between the responses (P ≤ 0.05). Most (72.67%) of the children were being accompanied by parents during their first dental visit. About 40.33% of the parents said that overall experience of the first visit of their children was good. About 39.67% of the children had positive behavior during their first dental visit. About 37.33% of the participants said that pain was the main reason for them to get their children to dentist. Conclusion: It was concluded that bulk of the parents were unaware about the appropriate age of their children's first dental visit. Most of the parents brought their children to dentist after their children experienced pain or suffered from dental caries. There is a need to raise awareness among masses regarding the importance of taking oral health care of their children quite seriously at the earliest budding stage of their life.
DESEMPENHO, EVASÃO E PERMANÊNCIA DOS ALUNOS INDÍGENAS E NEGROS QUILOMBOLAS INGRESSANTES PELO PROGRAMA UFGINCLUI DA UNIVERSIDADE FEDERAL DE GOIÁS - REGIONAL JATAÍ
Authors: Santos Débora Sirno , Paniago Maria de Lourdes Faria dos Santos 
Published: October 2018

O presente estudo analisa o desempenho acadêmico dos discentes ingressantes nos Cursos da Universidade Federal de Goiás, Regional Jataí, pelo Programa UFGInclui criado pela Resolução CONSUNI nº 29/2008, destinado a discentes que se autodeclararam indígenas e negros quilombolas. Sabendo que a Regional Jataí da Universidade Federal de Goiás possui 7 indígenas e 8 negros quilombolas ingressantes pelo programa UFGInclui, a presente pesquisa tem como objetivo analisar o desempenho acadêmico desses discentes, verificando a utilização e a relevância das políticas de permanência. O estudo configura-se como uma pesquisa qualitativa a presente investigação se desenvolve a partir de pesquisa bibliográfica, pesquisa documental e pesquisa empírica. O referencial teórico adotado ancora-se nas análises de autores como: Brandão (2005), Chauí (2001), Foucault (1970) e outros. É objeto de análise o seguinte corpus documental: a legislação, que compreende as políticas de educação superior no Brasil; os ordenamentos legais, resoluções e normativas específicas da UFG; dados estatísticos provenientes do sistema utilizado pela UFG – SIGAA, sobre o desempenho acadêmico dos discentes do programa UFGInclui. O presente estudo foi realizado com os alunos ingressantes pelo programa UFGInclui, indígenas e negros quilombolas provenientes de escolas públicas, os quais tiveram participação voluntária, com o direito reservado de se retirar da pesquisa em qualquer etapa, e com a garantia de confidencialidade e sigilo das informações coletas. Os dados foram coletados com 15 dos 16 discentes, tendo em vista que houve evasão de um aluno negro quilombola. Para coleta de dados aplicou-se questionário semiestruturado e realizaram-se entrevistas semiestruturadas, análise documental e observações diretas. Os resultados do estudo revelam que o desempenho acadêmico dos discentes cotistas acompanha o desempenho da turma. Os discentes relataram que, se não houvesse as políticas de permanência da UFG Regional Jataí, já teriam desistido do Curso, pois não conseguiriam se manter na Universidade e longe da família sem o auxílio financeiro e o acompanhamento Pedagógico.
Objective structured clinical examination versus traditional clinical examination among nursing students: A comparative approach
Authors: Nafee Hoda Mohamed , Ahmed Awatef El-Sayed , Hussien Ahlam Mohamed 
Published: September 2018

The complex nature of clinical competence in nursing consequently poses a challenge in identifying suitable assessment methods that are able to measure all its attributes as well as maintaining reliability, validity and objectivity. So the aim of this study was to compare nursing students’ opinions, feedback and clinical achievements grades in the Objective Structured Clinical Examination (OSCE) and the Traditional Clinical Examination (TCE) methods. A descriptive research design was used to conduct the study at college of nursing –Immam Abdulrahman Bin Faisal University (IABU), kingdom of Saudi Arabia. A total of 96 undergraduate student nurses enrolled in the pediatric nursing course equally were divided randomly into TCE and OSCE group (n = 48) in each group. Two tools were used, first tool was a structured questionnaire form to collect data related student’s academic number, age, method of exam used, achievement grades in the exam and the overall suggestions to improve the method of exam used where the second tool was a self-administered questionnaire that modified from a Pierre et al. (2004) OSCE feedback questionnaire which included 23 items and categorized under four main dimensions with 3-point Likert scale ranged from agree, neutral and disagree to evaluate students’ opinions and feedback related to the quality, organization, scoring and physical set up of both methods. Results revealed that statistical significant differences were found with higher prevalence of agreement responses among students for OSCE methods related most of items listed in the four dimensions compared to those in TCE. Mean ± SD total score of students’ responses related to OSCE and TCE methods was 104.5 ± 15.6 and 95.3 ± 17.5 respectively where p value = .002. Majority of students 95.8% exposed to OSCE compared to 11.9% of them who exposed to the TCE achieved (A) excellent grades in the exam (score 90%-100%). Conclusion and recommendation, statistical significant differences were observed between students’ opinion and feedback with high prevalence of agreement responses related to OSCE compared to TCE methods. Clinical achievement grade was high among students whom evaluated by OSCE compared to those evaluated by TCE method. The study recommended that OSCE must be used as an integral part of the under graduate nursing students’ clinical assessment.
Serum estradiol in the differential diagnosis of ectopic pregnancy
Authors: Craig Zane G. , Ramey Jack M. , Rochowiak, Michael W. , Brown Lawrence H. , DO, Howard Teitelbaum, 
Published: October 2018

Abstract
In a prospective study using a cutoff value of 140 pg/mL, serum estradiol 17-B assay had a sensitivity of 83% and a specificity of 100% in differentiating ectopic pregnancy (6 patients) from normal pregnancy with threatened abortion proceeding to viability (7 patients). In differentiating threatened abortion from spontaneous abortion (9 patients), the estradiol assay had a sensitivity of 88.9% and a specificity of 100%. All but one of the patients with ectopic pregnancy had estradiol levels below the cutoff value of 140 pg/mL, as did all but one of the patients who had spontaneous abortion. All the patients who had threatened abortion that progressed to viability had values well above the cutoff level. The mean estradiol values for the viable pregnancy group were significantly different from those of the other two groups. These data suggest that, at the institution where this study was done, serum estradiol determinations may be of value in the differentiation of both ectopic pregnancy and spontaneous abortion from threatened abortion but appears to be of very limited usefulness in distinguishing ectopic pregnancy from spontaneous abortion. The validity of these conclusions is limited by the small number of subjects. Further studies comprising greater numbers of subjects are needed.
Profile of nurses from Cape Verde/Africa: the influencing factors of life quality / Perfil dos enfermeiros de Cabo Verde-África: fatores que influenciam a qualidade de vida
Authors: Semedo Deisa Salyse dos Reis , Pelzer Marlene Teda , Ventura Jeferson , Paula Saul Ferraz de , Moniz Ana Suzete Baessa , Semedo José António Cabral 
Published: October 2018

Descrever o perfil e os fatores que influenciam a qualidade de vida dos enfermeiros de um hospital de grande porte de Cabo Verde-África. Metodologia: Pesquisa descritiva simples com uma abordagem quantitativa. Participaram 40 enfermeiros. Os dados foram coletados em junho e julho de 2015, analisados com o programa Statistical Package for the Social Science (SPSS) versão 20.0. Resultados: 72,5% são do sexo feminino e 27,5% do sexo masculino, 40% estão numa faixa etária entre 36 a 45 anos, 52,5% são solteiros (as). Dos fatores que influenciam a qualidade de vida, 19,4%, referiram a baixa remuneração, 15,7% condições de trabalho e motivação, 13,1% carga horária e estresse. Conclusão: a partir dos fatores que influenciam a qualidade de vida dos enfermeiros foi possivel identificar a necessidade de mudanças com o intuito de fornecer melhores condições de trabalho e renda para os enfermeiros cabo-verdianos.
Association of κ‐carrageenan subjected to deep alkaline hydrolysis
Authors: Gasilova Ekaterina R. , Aleksandrova Galina P. , Vlasova Elena N. , Baigildin Vadim A. 
Published: September 2018

Abstractκ‐carrageenan is a linear sulfated anionic gelling polysaccharide obtained from red seaweed algae by an alkaline hydrolysis. We applied static and dynamic light scattering (DLS), capillary viscometry, FT‐IR, and electrophoretic DLS to gain insight into the effect of deep alkaline hydrolysis (95 °C, pH = 10 during Th = 60, 75, and 90 min) on κ‐carrageenan macromolecules in a coil conformation. As DLS of coil‐like κ‐carrageenans is usually complicated by spurious permanent aggregates, the alkaline hydrolysis of κ‐carrageenans has not been studied by DLS. By applying a double‐dialysis procedure (first against water, then against 0.1 M NaCl), we succeeded in obtaining dilute solutions of coil‐like κ‐carrageenans with unimodal DLS distributions. Association that started with increasing concentration was attributed to attractive dipole‐dipole interactions between ion‐pairs formed by condensed counter‐ions in the vicinity of carboxyl groups of the reducing ends. The second type of stickers resulted from the compositional heterogeneity of κ‐carrageenan, namely, from the traces of ι‐carrageenan blocks which amount increased with hydrolysis. With increasing Th we observed both the progressive decrease of molecular mass and the growth of association. Lowering the temperature and increasing concentration during lyophilization strengthened the intermolecular junctions, leading to the formation of permanent aggregates.
Bioresorbable vascular scaffold implantation for severely calcified lesions after excimer laser lesion preparation
Authors: Mitomo Satoru , Jabbour Richard J. , Latib Azeem , Colombo Antonio 
Published: September 2018

AbstractBioresorbable vascular scaffolds (Absorb BVS, Abbott Vascular, Santa Clara, CA) temporarily elute antiproliferative drugs and provide vessel support, which then subsequently resorb to allow restoration of normal vessel function and architecture. To attain the best possible results with BVS, a dedicated implantation technique (PSP: adequate lesion preparation, proper sizing, postdilatation) is considered mandatory, and calcified lesions are one of the most challenging lesion subsets for BVS implantation. In five cases with severe calcifications refractory to balloon predilatation, we performed excimer laser catheter ablation (ELCA: Turbo Elite catheter; Spectranetics Corporation, Colorado Springs, CO, USA), which facilitated adequate lesion expansion with high‐pressure noncompliant balloon inflation and BVS implantation. During the follow‐up period (481 days [interquartile range: 445–579]), all patients continued dual antiplatelet therapy (DAPT) and there were no cases of cardiac death, myocardial infarction, or scaffold thrombosis. For treatment of severely calcified lesions with bioresorbable scaffolds, ELCA could be considered an effective potential strategy. After the procedure, prolonged DAPT was prescribed.
Coronary sinus reducer for the treatment of chronic refractory angina pectoris‐results of the preclinical safety and feasibility study
Authors: Konigstein Maayan , Shofti Rona , Schwartz Marc , Banai Shmuel 
Published: September 2018

AbstractBackgroundNarrowing of the coronary sinus (CS) has recently emerged as a new therapeutic option for the treatment of patients with chronic refractory angina pectoris. The results of the preclinical study presented here, evaluate the safety, feasibility, and efficacy of reducer implantation in a swine model with and without myocardial ischemia.Methods and resultsThe study included a safety/feasibility arm, and a safety/efficacy arm. In the safety/feasibility arm, reducers were implanted in 26 mini swine; follow up of up to 6 months included cardiac catheterization with CS angiogram, and histological evaluation of the stented segments of the CS. In the safety/efficacy arm, eight swine with evidence of inducible myocardial ischemia were divided into reducer implantation group (n = 4) and a control group (n = 4). Follow‐up in this arm included 6 weeks and 6 months dobutamine stress echo and myocardial contrast echo to evaluate severity and extent of ischemia.In the safety/feasibility arm (n = 26), reducers were implanted with procedural success rate of 100% and with no short or long‐term complications. All CS reducers were found to be patent at the time of sacrifice. In the safety/efficacy arm, all four animals with myocardial ischemia that underwent reducer implantation showed improvement in ischemia parameters at 6 weeks and 6 months follow‐up, with no mortality. Among the control group, no improvement in ischemia parameters was observed and three out of four animals died.ConclusionsNarrowing of the CS using percutaneous implantation of the reducer in swine is feasible, safe, and improves the extent and severity of ischemia.
Intra‐aortic balloon counterpulsation pump in heart failure patients during MitraClip implantation—A propensity‐score matched analysis
Authors: Keßler Mirjam , Seeger Julia , Wöhrle Jochen , Rottbauer Wolfgang , Markovic Sinisa 
Published: September 2018

AbstractObjectivesTo analyze 30‐day and 6‐month results after percutaneous mitral valve repair using an IABP as circulatory support.BackgroundThe use of intra‐aortic balloon counterpulsation pump extended the spectrum of cardiovascular interventions.MethodsSince 2014, 17 patients of 365 patients (4.7%) at our center received an IABP during MitraClip implantation procedure. We compare the periprocedural results to a control group of 17 patients treated with MitraClip without an IABP support. To adjust for differences of baseline characteristics a propensity‐score matching for age, baseline blood pressure, preoperative EuroSCORE II and left ventricular ejection fraction was performed. The decision for prophylactic implantation of an IABP was at the discretion of the interventionalist. For both groups, clinical results up to 6 months were evaluated.ResultsThe IABP group had higher NT‐pro BNP levels at baseline and increased left ventricular diameters. The procedure was more often categorized as “urgent” due to refractory heart failure in the IABP group. All procedures were carried out successfully, thereby achieving a sufficient MR reduction in both groups. Length of hospital stay was significantly longer in the IABP group 11.7 ± 14 days (compared to 6.5 ± 2.9 days in the No IABP group, P < 0.01). All patients in both groups had an event‐free 30‐day follow‐up. MACCE rate was higher in the IABP group compared to the No IABP group (47.1% vs. 23.5%, P = 0.14).ConclusionInsertion of an IABP during MitraClip procedure might be a feasible option to achieve comparable results and may provide additional safety and procedural hemodynamic stability in the setting of high‐risk percutaneous mitral valve repair.
Role of Transcatheter patent ductus arteriosus closure in extremely low birth weight infants
Authors: Sathanandam Shyam , Balduf Kaitlin , Chilakala Sandeep , Washington Kristen , Allen Kimberly , Knott‐Craig Christopher , Rush Waller Benjamin , Philip Ranjit 
Published: September 2018

AbstractBackgroundPatent ductus arteriosus (PDA) is common in extremely low birth weight (ELBW) infants. The objectives of this study were to describe our early clinical experience of transcatheter PDA closure (TCPC) in ELBW infants, compare outcomes with surgical ligation of PDA (SLP), and identify risk factors for prolonged respiratory support.MethodsA retrospective review was performed comparing infants born <27 weeks, weighing <1 kg at birth and < 2 kg during TCPC with 2:1 propensity‐score matched group of infants that underwent SLP. Change in respiratory severity scores (RSS) immediately post‐procedure and the time taken for return to pre‐procedure RSS for TCPC versus SLP was compared. Factors contributing to prolonged elevation of RSS were identified.ResultsEighty ELBW infants (median procedure weight: 1060 [range 640–2000] grams) that underwent successful TCPC were compared with 40 infants that underwent SLP (procedure weight 650–1760 g). There was greater increase in RSS following SLP compared to TCPC (76% vs. 18%; P < 0.01). It took longer for RSS to return to pre‐procedural scores post‐SLP compared to post‐TCPC (28 vs. 8.4 hr; P < 0.01). Elevated pulmonary artery pressure (PAP) and TCPC at >8 weeks of age were associated with prolonged (>30‐days) elevation of RSS ≥ 1 (OR = 5.4, 95%CI: 2.2–9.4, P < 0.01 and OR = 2.86, 95%CI: 1.5–4.2, P = 0.05 respectively). Overall complication rate for TCPC was 3.7%.ConclusionsTCPC is feasible in infants as small as 640‐2000 g and can be performed safely in the majority. TCPC may offer faster weaning of respiratory support compared to SLP when performed earlier in life, and before the onset of elevated PAP.
Validation and comparison of non‐hyperemic pressure reserve to fractional flow reserve for assessment of coronary artery stenosis: A real world study
Authors: Aoun Joe , Lahsaei Saba , Zahm Caroline , Bhat Tariq , Carrozza Joseph P. 
Published: September 2018

AbstractBackgroundThe visual interpretation of an angiographic stenosis may not always reflect the physiological significance of a lesion. Fractional Flow Reserve (FFR) is a reliable index to assess the significance of a lesion during hyperemia. However, there are pitfalls that can lead to significant misinterpretation and adverse events.ObjectiveThis study sought to evaluate the accuracy and predictability of the non‐hyperaemic pressure ratio (NHPR) without hyperemic stimuli, compared to hyperemic FFR.MethodsWe conducted a retrospective, multicenter study of 700 patients who underwent a pressure recording during coronary angiography using NHPR and FFR measurements. Receiver operator characteristic (ROC) curve was constructed. NHPR sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy test were calculated. The most accurate NHPR cutoff was determined.ResultsOf the 700 procedures, 449 cases were included. By ROC analysis, the optimal cut‐point for NHPR was 0.93 to predict an FFR of ≤0.80 with an overall diagnostic accuracy of 78.84%. The sensitivity of this NHPR cutoff was 85.06%, specificity of 75.59%, PPV of 64.53% and a NPV of 90.65%. There was an overall accuracy of about 80% for predicting non‐hyperemic index (FFR < 0.80) using a cutoff of NHPR ≤ 0.93.ConclusionsThe use of NHPR can be considered in certain clinical scenarios where adenosine is contraindicated or there are other challenges; with the knowledge that hyperemia might be necessary if there is any high clinical suspicion as it still remains the reference standard for diagnostic certainty.
Safety and efficacy of transcatheter aortic valve replacement for native aortic valve regurgitation: A systematic review and meta‐analysis
Authors: Rawasia Wasiq Faraz , Khan Muhammad Shahzeb , Usman Muhammad Shariq , Siddiqi Tariq Jamal , Mujeeb Firzah Abdul , Chundrigar Mohsin , Kalra Ankur , Alkhouli Mohamad , Kavinsky Clifford J , Bhatt Deepak L. 
Published: September 2018

AbstractObjectiveThe objective of this study was to analyze the available literature on using transcatheter aortic valve replacement (TAVR) for native aortic regurgitation (AR).BackgroundSurgical aortic valve replacement is the gold standard therapy for native AR. TAVR has emerged as an alternative approach in high‐risk patients.MethodsMEDLINE, Scopus, and Cochrane CENTRAL were searched for reports of at least 5 patients undergoing TAVR for native AR. Outcomes included 30‐day mortality, myocardial infarction, stroke, major bleeding, postprocedural moderate to severe AR, and device success. Pooled estimates were calculated using a random‐effects model. Subgroup analysis and a meta‐regression were performed to study the effects of study level covariates on outcomes.ResultsNineteen studies (n =998 patients) were included. The rate of procedural success per Valve Academic Research Consortium – 2 (VARC‐2) criteria was 86.2% (78.8%–92.2%]. Thirty‐day mortality was 11.9% (9.4%–14.7%). Subgroup analysis showed the use of new generation valves was associated with lower 30‐day mortality (P = 0.02) and higher device success (P = 0.009) compared with early generation valves. There was no significant difference (P = 0.13) in the rate of 30‐day mortality between patients receiving purpose‐specific [8.2% (4.3%−13.1%); I2 = 0%] and nonpurpose specific valves [13.0% (8.2%–18.6%); I2 = 25%]. However, device success was higher (P = 0.02) in patients who received purpose‐specific valves [96.3% (92.2%−98.9%); I2 = 0%] compared with nonpurpose specific valves [84.4% (75%−91.9%); I2 =46%].ConclusionTAVR for native AR is associated with acceptable procedural success but increased early mortality. However, the safety and the efficacy of the procedure increased with newer valves.