bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN TINGKAT PENGETAHUAN DAN DIABETES SELF-MANAGEMENT DENGAN TINGKAT STRES PASIEN DIABETES MELITUS YANG MENJALANI DIET
Authors: Kusnanto Kusnanto , Sundari Putri Mei , Asmoro Candra Panji , Arifin Hidayat 
Published: May 2019

Pengetahuan sangat penting dalam mengembangkan diabetes self-management untuk mencegah resiko komplikasi jangka panjang dengan diet yang ketat. Tujuan penelitian ini untuk mengetahui hubungan antara pengetahuan dan diabetes self-management dengan tingkat stress pasien diabetes melitus yang menjalani diet. Penelitian ini menggunakan desain cross-sectional. Jumlah total sampel didapatkan sebesar 106 responden dengan multistage sampling, Kriteria inklusi meliputi pasien DM <5 tahun dengan rentang usia 35-55 tahun, tidak menggunakan insulin injeksi, Pasien DM masih berkeluarga dan tinggal dengan keluarganya. Data didapatkan dengan kuesioner Knowledge of Diabetic Diet Questionnaire, Self-Management Dietary Behaviors Questionnaire, dan tingkat stress menjalani diet. Kemudian dianalisis dengan uji Spearman test. Hasil penelitian menunjukkan bahwa tingkat pengetahuan (p=0,049; r=-0,192) dan diabetes self-management (p=0,000; r=-0,341) memiliki hubungan terhadap tingkat stress saat menjalani diet. Diabetes self-management memiliki hubungan yang sangat kuat dari pada tingkat pengetahuan terhadap tingkat stress pasien diabetes yang menjalani diet. Penelitian selanjutnya diharapkan bisa menggunakan responden dengan wilayah yang lebih luas dan serta mengembangkan intervensi yang lebih baik untuk meningkatkan pengetahuan tentang diet pada pasien diabetes melitus. Kata Kunci: diabetes melitus, diet, self-management, tingkat stres Abstract The correlation between knowledge level and diabetes self-management towards stress level of patients DM with diet. Knowledge is very important in developing diabetes self-management to prevent the risk of long-term complications with a strict diet. The purpose of this study was to determine the relationship between knowledge and diabetes self-management with stress levels of people with diabetes mellitus who went on a diet. This study uses a cross-sectional design. The total samples obtained were 106 respondents with multistage sampling, inclusion criteria included patients with DM <5 years with a range of ages 35-55 years, did not use insulin injection, DM patients were still married and lived with their families. Data are obtained with questionnaire of Knowledge of Diabetic Diet Questionnaire (KDDQ), a Self-Management Dietary Behaviors Questionnaire (SMDBQ), and a stress level on a diet. Data analyzed by the Spearman Rho. The results showed that the level of knowledge (p=0.049; r=-0.192) and diabetes self-management (p=0,000; r=-0,341) had a relationship to stress levels while on a diet. Diabetes self-management has a very strong relationship to the level of knowledge of the stress level of diabetics with diet. Future studies are expected to be able to use respondents with a wider area and develop better interventions to increase knowledge about diets in people with diabetes mellitus. Keywords: diabetes mellitus, diet, self-management, stress level
DISTRACTION TECHNIQUES: TELLING STORIES TO DECREASE PAIN FOR PRESCHOOL CHILDREN DURING INFUSION
Authors: Anggraeni Lina Dewi , Widiyanti Widiyanti 
Published: May 2019

Hospital procedures, such as infusions, are often associated with pain. Preschool-aged children who are hospitalized for infusions will often exhibit a strong fearful response because their concept of body integrity has not fully developed. One way to reduce the fear of infusion pain is by using stories as a distraction technique. The purpose of this study was to identify differences in the scale of pain between members of an intervention group, to which the distraction technique was applied, and a control group, to which it was not applied. The study used quasi-experimental methods, with intervention and control groups. The study was conducted on 46 preschool aged respondents (3-6 years old), divided into a 34 member intervention group and a 12 member control group and ran from September to December 2017 in one of the private hospitals in the East Bekasi. The research employed a questionnaire to collect demographic data and used the Wong-Baker Faces Pain Scale to assess pain levels. The data analysis technique used was the independent t-test. The results showed there was a difference of pain response between the intervention and control groups with P value < 0.05. Pediatric nurses are advised to use storytelling therapy as an option for providing atraumatic care intervention. Keywords: Distraction Technique, Infusion installation, Pain, Stories, Preschool Abstrak Teknik Distraksi: Bercerita Menurunkan Nyeri Pada Anak Usia Pra Sekolah Selama Penggunaan Infus. Rasa sakit seringkali dikaitkan dengan salah satu prosedur rumah sakit yakni pemasangan infus. Reaksi anak prasekolah yang dipasang infus menunjukkan ketakutan yang luar biasa, hal itu disebabkan karena konsep integritas tubuhnya belum berkembang dengan baik. Salah satu cara untuk mengurangi ketakutan akibat nyeri pemasangan infus pada prasekolah adalah teknik distraksi bercerita. Tujuan penelitian ini untuk mengidentifikasi perbedaan skala nyeri antara kelompok intervensi dan kelompok kontrol. Penelitian ini merupakan penelitian kuantitatif dengan metode quasy eksperimen, yang menggunakan kelompok intervensi dan kelompok kontrol. Penelitian dilakukan terhadap 46 responden usia prasekolah (3-6 tahun) yang terdiri dari 34 kelompok intervensi dan 12 kelompok kontrol dari bulan September-Desember 2017 di salah satu Rumah Sakit Swasta di wilayah Bekasi Timur. Instrumen penelitian menggunakan kuisioner data demografi dan lembar observasi skala nyeri Wong Baker Faces Pain. Teknik analisis data menggunakan Uji Independent T test.Hasil penelitian menunjukkan terdapat perbedaan respon nyeri antara kelompok intervensi dan kelompok kontrol dengan nilai p= 0,012 (< 0.05). Perawat anak sebaiknya menggunakan metode bercerita sebagai sarana asuhan keperawatan atraumatik. Kata kunci: Cerita, Nyeri, Pemasangan infus, Prasekolah, Teknik distraksi
Costus Root Extract Alleviates Blood Biochemical Derangements of Experimentally-Induced Hypo- and Hyperthyroidism in Mice
Authors: Bolkiny Yousry , Tousson Ehab , El-Atrsh Afaf , Akela Mohamed , Farg Eman 
Published: May 2019

Objectives: Thyroid hormones regulate all metabolic activities; therefore, it is not amazing that hepatic; renal dysfunctions and lipid alterations are commonly detected in patients with thyroid disorders. This study estimated some biochemical changes in post pubertal hyperthyroid and hypothyroid mice and their impacts on liver and kidney functions and also on changes in the lipid pattern. In addition, the ameliorating role of Costus root extract supplementation was examined. Material and Methods: A total of 60 male Swiss albino mice were randomly divided into 5 groups; control, control with costus extract, hypo- and hyper-thyroids post-treated with costus root extract. Results: Present results revealed that, a significant increase in serum thyrotropin (TSH), alanine transaminase (ALT) and aspartate transaminase (AST), alkaline phosphatase (ALP), creatinine, urea, potassium, chloride, cholesterol and triglycerides levels in hypothyroid mice compared to control. On the other hand; a significant decrease in serumthyroxine (T4), tri‐iodothyronine (T3), albumin, total protein and calcium ions levels in hypothyroid mice compared to control. In contrast to hypothyroidism, a significant increase in serum T3, ALT, AST, ALP, creatinine, urea, sodium, potassium, chloride and total proteins levels in hyperthyroid mice compared to control. On the other hand; a significant decrease in serum TSH, T4, albumin, calcium ions cholesterol and triglycerides levels in hyperthyroid mice compared to control. Treatments of mice with Costus root extract in both hypo- and hyperthyroidism modulates the measured serum parameters.
Conclusions: Our results could propose that the extract of Costus roots can be used as an adjuvant co-therapy in hypo- and hyperthyroidism syndromes with propylthiouracil and Eltroxin replacement therapy, respectively
New Conditions That Guarantee Uniform Asymptotically Stable and Absolute Stability of Singularly Perturbed Systems of Certain Class of Nonlinear Differential Equations
Authors: Peter Ebiendele , Osoria Asuelinmen 
Published: May 2019

The objectives of this paper is to investigate singularly perturbed system of the fourth order differential equations of the type, to establish the necessary and sufficient new conditions that guarantee, uniform asymptotically stable, and absolute stability of the system. The Liapunov’s functions were the mathematical model used to establish the main results of this study. The study was motivated by some authors in the literature, Grujic LJ.T, and Hoppensteadt, F., and the results obtained in this study improves upon their results to the case where more than two arguments was established.
Frequency Diverse Phased Arrays
Authors: Wang Wen‐Qin 
Published: May 2019

AbstractThis article introduces what frequency diverse array (FDA) is and why it could be utilized in radar and wireless communication systems for improved performance. Recent advances and potential applications together with the technical challenges are discussed. It is shown that FDA indeed provides promising potential for future radar, communications, and even integrated radar and communication applications. However, for practical applications further work on system implementation, optimal array signal processing, and time‐variance related problems should be carried out.
Identification and functional characterization of a bacterial homologue of Zeta toxin in Leishmania donovani
Authors: Srivastava Akriti , Garg Swati , Jain Ravi , Ayana Rajagopal , Kaushik Himani , Garg Lalit , Pati Soumya , Singh Shailja 
Published: May 2019

Zeta‐toxin is a cognate toxin of epsilon antitoxin of prokaryotic Type II toxin‐antitoxin system (TA) and play an important role in cell death. An orthologue of bacterial‐zeta‐toxin (BzT) was identified in Leishmania donovani with similar structural and functional features. Leishmania zeta‐toxin (named Ld_ζ1) harboring similar UNAG and ATP‐binding pockets showed UNAG kinase and ATP‐binding activity. An active Ld_ζ1 was found to express in infective extracellular promastigotes stage of L. donovani and episomal overexpression of an active Ld_ζ1domain‐triggered cell death. This study demonstrates the presence of prokaryotic‐like‐zeta‐toxin in eukaryotic parasite Leishmania and its association with cell death. Conceivably, phosphorylated UNAG or analogues, the biochemical mimics of zeta‐toxin function mediating cell death can act as a novel anti‐leishmanial chemotherapeutics.
Critical Information Literacy
Authors: Drabinski Emily , Tewell Eamon 
Published: May 2019

Abstract
Critical information literacy seeks to challenge forms of oppression by identifying issues with and taking action upon the social, political, and economic dimensions of information. Critical information literacy is rooted in critical theory and most often critical pedagogy, and opposes traditional formulations of information literacy that fail to account for complexities and inequalities in the production and distribution of knowledge. While critical information literacy is not limited to education, it is most often applied by library workers to their educational efforts with library users, including information literacy instruction. Being a theory and practice concerned with information broadly, particularly as related to libraries, critical information literacy overlaps to some degree with critical media literacy, with a shared interest in encouraging learners to critically evaluate, use, and create information.
Evaluation of video compression methods for cone‐beam computerized tomography
Authors: Yan Hui , Li Yexiong , Dai Jianrong 
Published: May 2019

AbstractPurposeCone‐beam computerized tomography (CBCT) is routinely performed for verification of patient position in radiotherapy. It produced a large amount of data which require a method to compress them for efficient storage. In this study three video compression algorithms were introduced and their performance was evaluated based on real patient data.Materials and methodsAt first CBCT images in multiple sets of a patient were transferred from reconstruction workstation or exported from treatment planning system. Then CBCT images were sorted according to imaging time (time‐prioritized sequence) or imaging location (location‐prioritized sequence). Next, this sequence was processed by a video compression algorithm and resulted in a movie. Three representative video compression algorithms (Motion JPEG 2000, Motion JPEG AVI, and MPEG‐4) were employed and their compression performance was evaluated based on the CBCT data of 30 patients.ResultsAmong three video compression algorithms, Motion JPEG 2000 has the least compression ratio since it is a lossless compression algorithm. Motion JPEG AVI and MPEG‐4 have higher compression ratios than Motion JPEG 2000 but come with certain image losses. For MPEG‐4, location‐prioritized sequences show higher compression ratio than time‐prioritized sequences. Based on the results achieved on the clinical target verification application, the registration accuracy of CBCT after decompression was comparable to that of the original CBCT.ConclusionsVideo compression algorithms could provide a higher compression ratio comparing to static image compression algorithm. Although the loss of CBCT image due to compression its impact on registration accuracy of patient positioning is almost negligible. Video compression method is an effective way to substantially reduce the size of CBCT images for storage.
Birth Outcomes and Disease Activity During Pregnancy in a Prospective Cohort of Women With Psoriatic Arthritis and Ankylosing Spondylitis
Authors: Smith Chelsey J. F. , Bandoli Gretchen , Kavanaugh Arthur , Chambers Christina D. 
Published: May 2019

ObjectiveTo add to data on adverse birth outcomes accounting for disease activity in women with psoriatic arthritis (PsA) and ankylosing spondylitis (AS).MethodsData were analyzed from women enrolled in the Organization of Teratology Information Specialists Autoimmune Disease Project from 2004 to 2018. Disease activity was measured according to the Health Assessment Questionnaire (HAQ) or Routine Assessment of Patient Index Data 3 (RAPID3) scores. Poisson regression was used to estimate adjusted risk ratios (ARRs) with 95% confidence intervals (95%CIs) for selected adverse pregnancy outcomes.ResultsCompared to healthy controls (n = 717), women with PsA (n = 117) were at increased risk for moderate preterm delivery (32–36 weeks’ gestation) (ARR1.81, 95%CI1.01–3.26), oligohydramnios (ARR3.79, 95%CI1.34–10.74), and cesarean delivery (ARR1.63, 95%CI1.26–2.12). Women withAS(n = 129) had an increased risk of delivering infants requiring intensive care (ARR1.67, 95%CI1.05–2.67). A highHAQscore at 32 weeks was associated with preterm delivery in women with PsA (ARR3.82, 95%CI1.51–9.67). In women withAS, a highRAPID3 score was associated with cesarean delivery (ARR5.82, 95% 1.06–31.78), and second trimester glucocorticoid use was associated with preterm delivery (ARR4.41, 95%CI1.57–12.41).ConclusionWomen with PsA andAShave increased risk for selected adverse pregnancy outcomes. Active disease and use of glucocorticoids may increase the risk for some adverse pregnancy outcomes in women with these conditions.
Combining Data Longevity with High Storage Capacity—Layer‐by‐Layer DNA Encapsulated in Magnetic Nanoparticles
Authors: Chen Weida D. , Kohll A. Xavier , Nguyen Bichlien H. , Koch Julian , Heckel Reinhard , Stark Wendelin J. , Ceze Luis , Strauss Karin , Grass Robert N. 
Published: May 2019

AbstractIn this paper the practical density of long‐term DNA storage is increased. Specifically, the DNA weight loading of silica sphere DNA storage is increased to 3.4 wt%, a ten‐fold increase compared to the previous state‐of‐the‐art. By applying a Layer‐by‐Layer (LbL) design with alternating layers of DNA and a polycationic molecule, namely polyethyleneimine (PEI), another dimension to DNA surface binding onto magnetic nanoparticles is added. A protective silica layer is grown on top of the multilayered nanoparticles to shield the DNA from external sources of damage. Accelerated aging experiments of the nanoparticles and the subsequent quantification of DNA stability via qPCR show a significantly lower degradation rate compared to unprotected DNA. The novel material is compared to previous DNA storage technologies, outperforming those in DNA storage density as well as stability. Finally, the storage of an 83 kB digital file in DNA through a successful readout of a 4991 oligonucleotide pool is demonstrated from particle encapsulation, through accelerated aging, to sequencing.
Addition of the Lewis Acid Zn(C6F5)2 Enables Organic Transistors with a Maximum Hole Mobility in Excess of 20 cm2 V−1 s−1
Authors: Paterson Alexandra F. , Tsetseris Leonidas , Li Ruipeng , Basu Aniruddha , Faber Hendrik , Emwas Abdul‐Hamid , Panidi Julianna , Fei Zhuping , Niazi Muhammad R. , Anjum Dalaver H. , Heeney Martin , Anthopoulos Thomas D. 
Published: May 2019

AbstractIncorporating the molecular organic Lewis acid tris(pentafluorophenyl)borane [B(C6F5)3] into organic semiconductors has shown remarkable promise in recent years for controlling the operating characteristics and performance of various opto/electronic devices, including, light‐emitting diodes, solar cells, and organic thin‐film transistors (OTFTs). Despite the demonstrated potential, however, to date most of the work has been limited to B(C6F5)3 with the latter serving as the prototypical air‐stable molecular Lewis acid system. Herein, the use of bis(pentafluorophenyl)zinc [Zn(C6F5)2] is reported as an alternative Lewis acid additive in high‐hole‐mobility OTFTs based on small‐molecule:polymer blends comprising 2,7‐dioctyl[1]benzothieno [3,2‐b][1]benzothiophene and indacenodithiophene–benzothiadiazole. Systematic analysis of the materials and device characteristics supports the hypothesis that Zn(C6F5)2 acts simultaneously as a p‐dopant and a microstructure modifier. It is proposed that it is the combination of these synergistic effects that leads to OTFTs with a maximum hole mobility value of 21.5 cm2 V−1 s−1. The work not only highlights Zn(C6F5)2 as a promising new additive for next‐generation optoelectronic devices, but also opens up new avenues in the search for high‐mobility organic semiconductors.
Photocatalytic Oxidative Iodination of Electron‐Rich Arenes
Authors: Narobe Rok , Düsel Simon J. S. , Iskra Jernej , König Burkhard 
Published: May 2019

AbstractA visible‐light‐mediated oxidative iodination of electron‐rich arenes has been developed. 2.5 mol% of unsubstituted anthraquinone as photocatalyst were used in combination with elementary iodine, trifluoroacetic acid and oxygen as the terminal oxidant. The iodination proceeds upon irradiation in non‐ or weakly‐electron donating solvents (DCM, DCE and benzene) wherein a spectral window in strongly coloured iodine solutions can be observed at around 400 nm. The method provides good to excellent yields (up to 98%) and shows excellent regioselectivity and good functional group tolerance (triple bonds, ketone, ester, amide). Moreover, the photo‐iodination was also upscaled to a 5 mmol scale (1.1 g). Mechanistic investigations by intermediate trapping and competition experiments indicate a photocatalytic arene oxidation and the subsequent reaction with iodine as a likely mechanistic pathway.magnified image
Glial injury in neurotoxicity after pediatric CD19‐directed chimeric antigen receptor T cell therapy
Authors: Gust Juliane , Finney Olivia C. , Li Daniel , Brakke Hannah M. , Hicks Roxana M. , Futrell Robert B. , Gamble Danielle N. , Rawlings‐Rhea Stephanie D. , Khalatbari Hedieh K. , Ishak Gisele E. , Duncan Virginia E. , Hevner Robert F. , Jensen Michael C. , Park Julie R. , Gardner Rebecca A. 
Published: May 2019

ObjectiveTo test whether systemic cytokine release is associated with central nervous system inflammatory responses and glial injury in immune effector cell‐associated neurotoxicity syndrome (ICANS) after chimeric antigen receptor (CAR)‐T cell therapy in children and young adults.MethodsWe performed a prospective cohort study of clinical manifestations as well as imaging, pathology, CSF, and blood biomarkers on 43 subjects ages 1 to 25 who received CD19‐directed CAR/T cells for acute lymphoblastic leukemia (ALL).ResultsNeurotoxicity occurred in 19 of 43 (44%) subjects. Nine subjects (21%) had CTCAE grade 3 or 4 neurological symptoms, with no neurotoxicity‐related deaths. Reversible delirium, headache, decreased level of consciousness, tremor, and seizures were most commonly observed. Cornell Assessment of Pediatric Delirium (CAPD) scores ≥9 had 94% sensitivity and 33% specificity for grade ≥3 neurotoxicity, and 91% sensitivity and 72% specificity for grade ≥2 neurotoxicity. Neurotoxicity correlated with severity of cytokine release syndrome, abnormal past brain magnetic resonance imaging (MRI), and higher peak CAR‐T cell numbers in blood, but not cerebrospinal fluid (CSF). CSF levels of S100 calcium‐binding protein B and glial fibrillary acidic protein increased during neurotoxicity, indicating astrocyte injury. There were concomitant increases in CSF white blood cells, protein, interferon‐γ (IFNγ), interleukin (IL)‐6, IL‐10, and granzyme B (GzB), with concurrent elevation of serum IFNγ IL‐10, GzB, granulocyte macrophage colony‐stimulating factor, macrophage inflammatory protein 1 alpha, and tumor necrosis factor alpha, but not IL‐6. We did not find direct evidence of endothelial activation.InterpretationOur data are most consistent with ICANS as a syndrome of systemic inflammation, which affects the brain through compromise of the neurovascular unit and astrocyte injury. ANN NEUROL 2019
Tactile UV‐ and Solar‐Light Multi‐Sensing Rechargeable Batteries with Smart Self‐Conditioned Charge and Discharge
Authors: Fang Zhengsong , Zhang You , Hu Xuanhe , Fu Xinlong , Dai Liming , Yu Dingshan 
Published: May 2019

AbstractA tactile, UV‐ and solar‐light multi‐sensing smart rechargeable Zn–air battery (SRZAB) with excellent cell performance, self‐conditioned charge/discharge, and reliable environmental responsivity is made by using multi‐scale conjugated block‐copolymer–carbon nanotube–polyurethane foam assemblies as both a self‐standing air electrode and a sensing unit. Multiscale engineering fully exploits the multi‐synergy among components to endow the newly designed metal‐free multi‐sensing air electrode (MSAE) with bifunctional oxygen reduction and evolution activities, pressure sensitivity, and photothermal and photoelectric conversion functions in a single electrode, enabling effective regulation of interface properties, electronic/ionic transport, or redox reactions in SRZAB upon various stimulations and establishing multiple working principles. MSAE‐driven SRZAB can be used as compressible power sources, self‐powered pressure and optical sensors and light‐to‐electrochemical energy systems.