bluuebunny/crossref_metadata_2025_split huggingface dataset:
STRATEGI PENGEMBANGAN USAHA RUMAH TANGGA
Authors: Fadhilah Andi , Darma Rahim , Amrullah A. 
Published: July 2019

This research has been done in Household Business “X”, which is located in Sidrap Regency, South Sulawesi. This research aims to: 1). Analyze the problems that happened in agrosystems case; 2). Analyze various solutions for problems in business development; 3). Formulate actions in achieving the objectives; 4). Implement selected actions. The whole data and information obtained in this research using the APPAS (Analysis of Agrosystem Design and Development) method and AHP (Analysis of Hierarchy Process). APPAS method is one of the learning methods that lead to overcome the problem in relation of the agrosystem case that used as the object of research and also directs to analyze the problem solving and AHP (Analysis Hierarchy Process) that is used to evaluate the alternative actions that must be done for the sake of development of agrosystem case. The result of the analysis shows that Household Business of “X” has the main problem that is Limited Marketing Area. The main problem happened due to the lack of promotion media, the manpower in the marketing department is unavailable, inadequate transportation, and limited equipment units. This main problem is the cause of low incomes, low demand, and low sales. To solve this problem, we have to set the main target that is increasing the revenue. The main target will be achieved if the media promotion increases, availability of manpower, transportation, and equipment units. Achieving the main targets will have an impact on increased of corporate revenue, the demand and the sales. Keywords: Strategy, Household Business, AHP (Analysis of Hierarchy Process)
Etiology, Evaluation, and Management of Dislocation After Primary Total Hip Arthroplasty
Authors: Saiz Augustine M. , Lum Zachary C. , Pereira Gavin C. 
Published: July 2019

» The rate of dislocation after primary total hip arthroplasty has decreased, but given the high volume of total hip arthroplasty procedures that are performed, dislocation remains a common complication.» The etiology of dislocation after total hip arthroplasty is multifactorial and depends on the patient’s characteristics as well as the orthopaedic surgeon’s operative techniques and decisions regarding implants.» A detailed assessment of the patient, preoperative planning, a thorough understanding of the anatomy, proper surgical technique, and knowledge of the biomechanics of the implant decrease the likelihood of dislocations following total hip arthroplasty.» The advent of new techniques and procedures has further reduced the occurrence of dislocation following total hip arthroplasty. However, should dislocation occur, primary management or revision total hip arthroplasty techniques provide excellent results to salvage the mobility and function of the hip.
Clinical Efficacy of Liposomal Bupivacaine
Authors: Abildgaard Jeffrey T. , Chung Andrew S. , Tokish John M. , Hattrup Steven J. 
Published: July 2019

Background:
There has been a surge in interest with regard to the utility of liposomal bupivacaine as part of a perioperative pain management protocol. The current study was proposed to critically assess the efficacy of liposomal bupivacaine as a local anesthetic for pain relief following orthopaedic procedures.

Methods:
A systematic review of prospective, randomized trials involving liposomal bupivacaine was performed using searches of the PubMed, Embase, and Cochrane databases. The primary outcomes of interest included postoperative subjective pain scores and narcotic consumption. The length of stay and postoperative mobility were reviewed as secondary outcomes.

Results:
Twenty-seven studies met inclusion criteria and were included for review. Twelve of 17 studies concluded that periarticular or local infiltrative liposomal bupivacaine offered no additive benefit compared with other local anesthetic injections. Peripheral nerve blocks without liposomal bupivacaine conferred more optimal pain relief and decreased narcotic consumption in the immediate postoperative period when compared with liposomal bupivacaine, with no differences thereafter. Twelve studies listed a conflict of interest related to the drug manufacturer (Pacira Pharmaceuticals). Eight of these studies (67%) demonstrated clinical superiority of liposomal bupivacaine when compared with the study control. In the 15 studies that did not show a conflict of interest, only 1 study (7%) demonstrated therapeutic superiority with use of periarticular liposomal bupivacaine when compared with a historical cohort that received no local or regional anesthesia.

Conclusions:
Current prospective, randomized controlled trials in patients undergoing orthopaedic surgery fail to support the routine use of liposomal bupivacaine compared with other local injectable analgesics, particularly in the setting of knee replacement surgery. We were unable to find consistent support for the potential of superior pain relief and narcotic use reduction with the use of liposomal bupivacaine.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Systematic Approach To Reduce Uncertainties When Quantitatively Assimilating 4D Seismic and Well Data
Authors: Almeida Forlan La Rosa , Davolio Alessandra , Schiozer Denis José 
Published: July 2019

SummaryHistory matching (HM) is a complex process that aims to increase the reliability of reservoir-simulation models. HM is an inverse problem with multiple solutions that call for probabilistic approaches. When observed data are integrated with sampling methods, uncertainty can be reduced by updating the uncertainty distribution of the reservoir properties. This work presents a practical methodology to systematically reduce uncertainties in a multiobjective assisted HM while dealing with multiple scenarios and assimilating well and 4D-seismic (4DS) data quantitatively. The frequency-distribution update goes through an iterative process. The distribution of the current iteration is combined with the histogram generated using the best-matched simulation scenarios from the current iteration to generate the updated distribution. To evaluate the matching quality, multiple local objective functions (LOFs) are independently evaluated, enabling the identification of LOFs that expose the need for reparameterization. This quantitative process was applied in two phases: Phase 1, in which only well data were used to constrain the scenarios, and Phase 2, when 4DS data were added. The methodology was successfully validated against a synthetic benchmark case of medium complexity, with the production-history data generated at a fine scale (reference model). Each iteration increased the number of matched scenarios, demonstrating good convergence. Most of the reservoir properties had uncertainty reduced gradually while avoiding the premature reduction of the uncertainty range (minimizing convergence to an incorrect solution). Local probabilistic perturbations were conducted on the petrophysical realizations in the regions around the wells that manifested LOFs, which hindered the match. The method efficiently achieved multiple matched simulation scenarios, with all (87) LOFs evaluated within the defined tolerance range. The 4DS data were included regionally with an acceptable increase in computation time. In both phases, the matched simulation scenarios presented production forecasts similar to the reference model. The quantitative assimilation of 4DS data generated scenarios that forecast production with less variability than did scenarios generated without 4DS data. This was expected for this study because the 4DS data provided do not present noise or artifacts.
Laryngopharyngeal pH monitoring in patients with interstitial lung diseases
Authors: Su Yiliang , Shen Li , Zhang Fen , Jiang Xing , Jin Xiaofeng , Zhang Yuan , Hu Yang , Zhou Ying , Li Qiuhong , Li Huiping 
Published: July 2019

Abstract
Background

Patients with interstitial lung diseases (ILDs) often have irritating persistent dry cough. Possible correlations between dry cough and laryngopharyngeal reflux (LPR) remain unclear.

Methods

44 patients with ILDs and 30 healthy individuals underwent 24-hour laryngopharyngeal pH monitoring. Ryan index score was calculated. Patients’ demographic and clinical data were collected.

Results

44 patients (23 cases of IPF and 21 cases of CTD-ILD) and 30 healthy individuals were included. The proportions of men and smokers were significantly higher in IPF group than in CTD-ILD group and control group (All P<0.01). Other demographic and clinical data were similar in IPF and CTD-ILD group. According to the percentage duration of pH<6.5, pH6.5-7.5, and pH>7.5 in the overall measure duration, the patients were classified into three pH groups. In entire pH monitoring duration, the proportion of pH>7.5 group in ILD patients was higher than control group; at upright position, the proportion of pH>7.5 group in ILD patients was higher than control group; at supine position, the proportion of pH<6.5 group in ILD patients was higher than control group (All P<0.01). Seven patients had Ryan index score>9.41 at upright position. All patients had Ryan index score<6.79 at supine position. Four patients showed significantly higher and one patient had significantly lower average pH at coughing than the overall average pH (All P<0.05).

Conclusions

Patients with ILDs may have LPR. Basic and acidic LPR may likely occur at upright and supine position, respectively. Ryan index may not accurately reflect LPR in patients with ILDs.
Prevalence of road traffic injury and its associated factors at hospitals in Wolaita Zone
Authors: Weldemariam Samuel Hailu , Lendado Tigabu Addisu 
Published: July 2019

Abstract
Background Road traffic injury is defined as fatal or non-fatal cases incurred as a result of road traffic crashes. It accounts for an estimated 1.2 million people death and as many as 50 million injury in each year worldwide. This study was aimed to determine prevalence and associated risk factors of road traffic injury.Objective To determine the prevalence and its associated risk factors of road traffic injury.Method Facility based cross-sectional study with sample size of 309 was used for conducting study in two selected hospitals in Wolaita Zone.Systematic sampling method was applied to select study subject based on inclusion criteria. Data was collected by questionnaires which was developed from reviewing different literatures and analysed by using SPSS version 20statistical software.Result Among the total of trauma victims who visited emergency department of hospitals, approximately half of victims (49.2%) were due to road traffic injury followed by falling injury 60 (19.4%) and burns 35 (11.3%). After adjusting for confounding in multivariate logistic regression analysis, sex and living places are independent factors of road traffic injury. Two of them are highly significantly associated with road traffic injury and being male and urban resident had thirteen times AOR 13.08 95% CI (6.15-27.85) and more than two times AOR 2.69 95%CI (1.55-4.64) increased odd of road traffic injury respectively.Conclusion Road traffic injury was leading injury types among trauma victims visiting emergency department of Hospitals. Therefore, strong road safety policy at local and country level is needed to reduce vulnerability of individuals and vehicle related injury.
A new video laryngoscope specialized for endotracheal intubation in mice
Authors: Sun Gang-Qiang , Guo Wen-jun , Xu Qing , Liu Chen , Fang Shang-Ping 
Published: July 2019

Abstract
Background: Mechanical ventilation is indispensable in many animal experiments, and establishing a stable airway to control breathing is critical. However, endotracheal intubation in small rodents is very difficult due to the lack of visibility of the epiglottis. In addition, traditional blind endotracheal intubation methods usually cause laryngopharyngeal injury and can even result in death; thus, a noninvasive endotracheal intubation device is needed. Results: The video laryngoscope required significantly less time and fewer attempts to achieve successful intubation. The incidences of vomiting reflex, asphyxia and injury were significantly lower in video laryngoscope group. In addition, the time elapsed until the first feeding postextubation was less in video laryngoscope group, indicating faster recovery. Conclusions: The new video laryngoscope endotracheal intubation device used in this study is simple, noninvasive, safe and practical.
Comparison of Safety and Efficacy of Open, Laparoscopic-Assisted, Totally Laparoscopic, and Robotic Gastrectomy for Gastric Cancer:A Network Meta-Analysis
Authors: Huang Chao , Huang Jun , Luo Hongliang , Zong Zhen , Zhu Zhengming 
Published: July 2019

Abstract
Background: Several techniques are used for surgical treatment of gastric cancer (GC), but the efficacy and safety of these approaches have not been compared.
Methods: We systematically searched articles of randomized controlled trials (RCTs) through PubMed, Embase, Cochrane Library and ISI-Web of Science databases. The primary outcome was safety using overall morbidity as the main indicator of safety. The secondary outcome was efficacy using the number of harvested lymph nodes (HLNs) as an indicator of efficacy. Multiple surgical treatment comparisons based on Bayesian network integrated the safety and efficacy of all included approaches. The ranking probability was appraised by the probability of the surgical approaches.
Results: The 19 eligible RCTs with 4309 patients were included in the network meta-analysis (NMA). There were no differences in overall morbidity between open gastrectomy (OG) and laparoscopic-assisted gastrectomy (LAG) [odds ratio (OR) 1.09, 95% credible interval (Crl): 0.86-1.64], OG and robotic gastrectomy (RG) (OR 1.16, 95% Crl: 0.43-3.07), LAG and totally laparoscopic gastrectomy (TLG) (OR 2.85, 95% Crl: 0.67-12.52), RG and LAG (OR 0.96, 95% Crl: 0.36-2.93), TLG and OG (OR 0.32, 95% Crl: 0.07-1.38) and TLG and RG (OR 0.35, 95% Crl: 0.06-2.01). There were also no differences in the number of HLNs between OG and LAG [weighted mean difference (WMD) 0.91, 95% Crl: -0.24-2.43)], OG and RG (WMD 1.55, 95% Crl: -2.58- 5.51), LAG and TLG (WMD -0.90, 95% Crl: -6.82-5.18), RG and LAG (WMD -0.68, 95% Crl: -4.63- 3.91), TLG and OG (WMD -0.01, 95% Crl: -6.41-5.90) and TLG and RG (WMD 1.56, 95% Crl: -6.01-8.59). From the results of the rank probabilities of the four surgical treatments, TLG had the highest probability of being the safest and the most effective surgical approaches.
Conclusions: The four surgical treatments of GC have similar safety and efficacy. TLG had the best chance of becoming the safest and most effective treatment.
Effect of acute primary angle closure glaucoma on the blood flow and macular structure: A prospective cohort study
Authors: wang rui , Yang Jin , Li Xuan 
Published: July 2019

Abstract
Background: Mounting evidence shows that vascular factors play an important role in the pathogenesis of glaucoma, while optical coherence tomography angiography (OCTA) can provide a better view for microvascular changes in glaucoma.
Objective: This study aimed to assess the effect of the severity of acute primary angle closure glaucoma (APACG) on macular microcirculation and the diagnostic value of blood flow and macular structure for APACG using OCTA.
Methods: Patients with APACG hospitalized at the Tianjin Eye Hospital from January to April 2019 were enrolled in this prospective cohort study. They were assigned to mean deviation (MD) ≤6 (35 eyes), 6 < MD ≤ 12 (41 eyes), MD >12 (33 eyes), primary angle closure suspect (PACS) (40 eyes), and age-matched age-related cataract (ARC) groups (33 eyes). OCTA was used to measure the vessel density (VD) and foveal avascular zone (FAZ) in different macular superficial areas. OCT was used to measure the retinal thickness (RT) and ganglion cell complex thickness (GCC). One-way analysis of variance was used to compare the differences in VD and FAZ for different degrees of APACG. Areas under the receiver operating characteristic curves (AUCs) were used to assess the diagnostic values of VD, RT, and GCC for APACG.
Results: On comparing the ARC, PACS, and MD ≤6 groups with 6 < MD ≤ 12 and MD > 12 groups, differences in all parameters were found to be statistically significant. This indicated that VD gradually decreased and FAZ enlarged with the exacerbation of APACG. For the 6 < MD ≤ 12 group versus PACS group, the diagnostic value of VD was high (AUCs: 0.902–0.942), and that of RT was moderate (AUCs: 0.805–0.842). For the MD >12 group versus PACS group, the diagnostic values of VD (AUCs: 0.900–0.958) and RT (AUCs: 0.828-0.887) increased.
Conclusions: With the exacerbation of APACG, the damage of VD in the macula was greater. VD had higher diagnostic accuracy, providing a new view for the diagnosis of APACG.
Comparison between endoscopic submucosal snaring with circumferential mucosal incision (ESS-CMI) and endoscopic submucosal dissection (ESD) in treating colonic neoplasm - a cost-effective retrospective study
Authors: Jin Xi , Yu Mosang , Zhu Yinxuan , Zheng Ruoheng , Huang Yue , Zhou Xinxin , Ji Feng 
Published: July 2019

Abstract
Background To evaluate and compare the safety, efficacy and cost of endoscopic submucosal snaring with circumferential mucosal incision (ESS-CMI) with endoscopic submucosal dissection (ESD) in various types of colonic neoplasms. Methods Patients who were admitted in our endoscopic center for colonic neoplasm therapy were screened, with the Chinese item of “endoscopic submucosal dissection” and the English abbreviation of ESD, for the period between January 2011 and December 2017. Initially enrolled patients were further categorized into ESD and ESS-CMI groups after careful assessment of detailed operation procedures. Data on patients’ and colonic neoplasm’s characteristics, recurrence, treatment, follow-up and disease status were collected after medical records review. Further cost-effective analysis includes two main aspects: treatment effect and complication as well as the cost and efficiency. Results A total of 278 patients was selected. Though there were no significant differences in basic anthropometric and disease status data such as age, gender, neoplasm type, degree and the method of follow up, the location of rectum, the longest side and the surface area were significantly higher in ESD group than those in ESS-CMI group. For ESS-CMI, further cost-effective study showed the similar treatment effect and complication rate but significantly decreased cost, operation time and average hospital stay, when compared with ESD. Further subgroup analysis showed that there were no significant differences between the ESS-CMI successful and failure groups. Conclusion ESS-CMI might become a new and better choice for colonic neoplasm therapy, based on its decreased operation cost but similar treatment efficacy and complication rate as ESD.
Care provider’s knowledge, attitude and practices toward chronic kidney disease in Jimma Town: Cross-sectional study
Authors: Wolide Amare Desalegn , Goro Kabaye Kumela , Dibaba Fantu kerga , Debalke Serkadis , Seboka Meskerem , Tufa Birtukan Edilu , Fufa Fanta Gashe , Bobasa Eshetu Mulisa 
Published: July 2019

Abstract
Introduction:Chronic kidney disease (CKD) is a common and growing health problem that requires adequate knowledge by health care providers to reduce the progress of the diseases. Thus, this study is aimed to asses the care provider’s knowledge, attitude, and practices toward CKD.

Method: Cross-sectional study was conducted among 326 care providers at Jimma University Specialized hospital and three medium to higher clinics found in Jimma Town. Collected data entered to Epi-Data version 3.1 and exported to SPSS version 21 for windows for data analysis. Descriptive statistics and generalized linear modal were used to analyze the data.

Result:The mean age and service year of the participants were 29.68(±4.877) and 4.28(±4.561), respectively. The overall weighted knowledge, attitude and practice score of the study participant was 9.0971(8.77, 9.42), 2.53(2.4,2.65), 10.14(9.94,10.33) respectively. More than half of the respondents 191 (58.6%) had the knowledge that eGFR (estimated Glomerular Filtration Rate) is a better way to assess kidney function. Many 215(66.0%) knew the five-stage and the risk factors of CKD. Above 250 study participant knew late detection and referral would increase kidney disease complication. In addition, 275(84.4%) of them are worried about treatment cost related to CKD. Over half of the care providers, 238(73.0%) believed that the Ethiopian ministry of health gave less attention to the problem. Furthermore, 234(71.8%) are interested to study more on CKD management. Majority 256(78.5%), very likely or likely refer patient to senior physician and Nephrologist.

Conclusion: Care provides knowledge was found to be above moderate level and many had the knowledge on the basic function of the kidney, risk factors, treatment, and management of CKD. Many are worried about treatment cost and interested to learn about CKD primary from textbook and internet. The majority had a practice of referring patients to nephrologists or to a senior physician. Many care providers had a frequent discussion on the prevention strategies of CKD.
Effectiveness of the serious game ‘You &amp; I’ in changing mentalizing abilities of adults with mild to borderline intellectual disabilities: A parallel superiority randomized controlled trial
Authors: Derks S.D.M. , Wijngaarden S. van , Wouda M. , Schuengel C. , Sterkenburg P.S. 
Published: July 2019

Abstract
Background: Persons with mild to borderline intellectual disabilities generally show dysfunctions in mentalization and stress regulation, resulting in problematic social relationships and personal distress. Intervention programs may improve mentalizing abilities. The aim of this study is to examine the effectiveness of the serious game ‘You & I’ in changing mentalizing abilities and stress regulation in adults with mild to borderline intellectual disabilities.
Methods: A two-arm, parallel, superiority randomized controlled trial will be used with 172 adults with mild to borderline intellectual disabilities. Participants will be randomly assigned to either the experimental group to play the serious game ‘You & I’ or to a waitlist control group. Participants will be assessed at baseline, post-intervention (5 weeks after baseline), and follow-up (6 to 8 weeks after post-intervention). They also will fill in questionnaires for personal factors, personal development, personal well-being, social validity, autism spectrum quotient (demographic variables), mentalizing abilities (primary outcome measure), and stress regulation (secondary outcome measure).
Discussion: The serious game ‘You & I’ aims to improve mentalizing abilities in adults with mild to borderline intellectual disabilities, which is expected to lead to improved regulation of stress in social relationships. The study’s unique feature is the use of a serious game to improve mentalizing abilities. If the intervention is effective, the serious game can be implemented on a broad scale in Dutch care organizations for people with intellectual disabilities as an effective preventive tool to improve mentalizing abilities.