bluuebunny/crossref_metadata_2025_split huggingface dataset:
STUDY OF THE EFFECT OF MODIFIERS WITH ULTRADISPERSED PARTICLES IN THE COATING OF THE ELECTRODE FOR MANUAL ARC WELDING ON THE TECHNOLOGICAL PARAMETERS IN MANUFACTURE OF THE ELECTRODE
Authors: Urbanovich N. I. , Melnichenko V. V. , Baranovsky K. E. , Rozenberg E. V. , Radchenko A. A. , Ignatovich Z. V. 
Published: July 2018

It is established that inclusion of the modifier into the electrode coating allowed to change the grains of the weld metal from 20–60 to 10–30 mm, to change its morphology and to improve the welding-technological properties of the coated electrode. It is shown that the modifying additive introduced into the coating of a welding electrode containing ultrafine particles in an amount of 1% of the weight of the dry charge had not deteriorated the technological parameters during manufacture, and the integral index of the different thickness (Desp) of electrodes with standard and experimental coatings did not add to the accepted value of 0.05. This indicates that the quality of the lubricating mass, its properties, the stability of the mass flow from the spinneret are satisfactory for both batches.
PARAMETRIC AMPLIFICATION OF THE SIGNALS IN THE ELECTROSTATIC GRAVIINERTIAL SENSOR
Authors: Gilavdary I. Z. , Mekid S. N. , Riznookaya N. N. 
Published: July 2018

The challenges of designing simple, reliable, and high sensitivity graviinertial sensors are investigated. The sensor comprises a proof mass (PM) and is fixed with the housing by the elastic torsion suspension. PM makes small rotations under the action of gravitational forces or inertial forces.The distinctive features of the sensor are that the differential electrostatic system provides simultaneous reading of the desired signal and a control the torsional rigidity of suspension. In addition, the PM's rotational angular velocity transforms in the alternating current flowing through the capacitors. The presence of аlternating current (AC) voltage sources allows to get the parametric amplification of AC and significantly to improve the sensitivity of the sensor. In the simplest case, the sensor does not contain any feedback circuits.As an example, calculations of the micromechanical linear accelerations confirm that the periodic modulation of the coefficient of elastic stiffness of the suspension can significantly increase the sensitivity in the low frequency range, even in the absence of parametric resonance.Conditions for suppressions of background current participating in the output signal from a parametric pumping due to the asymmetry of the differential circuits are set. The frequency characteristics calculations of the sensor were carried out. It is expected, that the proposed sensor design ensures minimum noise level, which can be achievable in the graviinertial sensors. This design and the constructed theory can serve as a basis for creating a wide range of graviinertial devices operating on a movable base, for example, linear and angular accelerometer, gravity gradiometer, gravimeters, and inclinometers, which can be realized in the hybrid and in the micromechanical versions.
PHYSICAL FIELDS OF CIRCULAR CYLINDRICAL PIEZOCERAMIC RECEIVER IN PRESENCE OF A FLAT ACOUSTIC SOFT SCREEN
Authors: Derepa A. V. , Leiko A. G. , Pozdniakova O. N. 
Published: July 2018

System in the form of a circular cylindrical piezoceramic transducer near a flat acoustic screen was analyzed. The aim of the work was to solve the problem of receiving plane sound waves by «cylindrical piezoceramic transducer – flat acoustically soft screen» system.Considered system was characterized by a violation of the radial symmetry of the radiation load of the transducer while maintaining the radial symmetry of the electric load. At the same time, the energy perceived by the system under consideration is distributed between all modes of oscillation of the transducer, while the conversion of mechanical energy into electric is realized only at zero mole of oscillations.Special attention was paid to the method of coupled fields in multiply connected domains using the imaging method. The design model of the «transducer–creen» system was formulated taking into account the interaction of acoustic, mechanical and electric fields in the process of energy conversion, the interaction of a cylindrical transducer with a flat screen and the interaction of a converter with elastic media outside and inside it. The physical fields of the system under consideration were determined by following solutions: the wave equation; equations of motion of thin piezoceramic cylindrical shells in displacements; equations of stimulated electrostatics for piezoceramics for given boundary conditions, conditions for coupling fields at interfaces and electrical conditions.A general conclusion was made concerning solving of an infinite system of linear algebraic equations with respect to the unknown coefficients of the expansion of the fields. As an example of the application of the obtained relations, a calculation was made and an analysis of the dependences of the electric fields of the system under consideration for various parameters of its construction on the direction of arrival on the plane wave system was conducted.
PRACTICAL IMPLEMENTATION OF HARDWARE AND SOFTWARE COMPLEX FOR PLANAR MEASUREMENTS OF ANTENNA CHARACTERISTICS IN THE NEAR ZONE
Authors: Buday A. G. , Grinchuk A. P. , Gromyko A. V. 
Published: July 2018

Directional patterns measurement of antennas is carried out by the methods of far and near zone. Measurements in the far zone are straightforward; however they have a number of disadvantages. Near zone measurement methods are free from measurement shortcomings in the far zone, but it requires complex and expensive equipment for its implementation.Earlier, the authors have developed a concept of hardware and software modular design complex to determine antenna system characteristics as per measurements in the near zone. This concept assumes creation of a universal measuring complex to investigate various types of antenna systems with any type of measurement surface (plane, cylinder, sphere) in order to solve a wide range of applied problems. The purpose of this work lies in practical implementation of a variant of this measuring complex for measurement along the plane and determination of its metrological (hardware and software) capabilities.A working experimental sample of hardware and software complex for measuring the characteristics of antenna systems that realizes a radio-holographic method for measuring along a plane has been developed, created and practically tested. A preliminary estimation of errors in amplitude and phase measurements in the dynamic range of 45 dB and a comparison of the characteristics of several types of antennas measured in far and near zones have been made. Algorithms have been developed, a software for processing, storing and graphical display of measurement results has been created.
INFLUENCE OF THE AVERAGE WEIGHTED ESTIMATION TYPE ON THE DEPENDENCE OF THE COMPLEX QUALITY INDEX ON THE PARAMETERS OF OBJECT
Authors: Dolzhanskiy A. M. , Bondarenko O. A. , Petlyovaniy Ye. A. 
Published: July 2018

Objects quality is usually assessed by a complex indicator. It includes single quality indicators with their significance factors. The convolution of the corresponding dependencies represents average weighted quantities: arithmetic, geometric, harmonic, quadratic, etc. At the same time, the influence of the convolution type on the level of the complex quality index, the stability of the calculation results and, the reliability of the quality comparison among a number of similar objects is unknown in advance. Therefore, the aim of the study was to assess the influence of the average weighted type on the level and stability of the calculating results of the complex quality index in different objects compressing.For typical private objects compared the values of the complex quality index calculated according to the formulas of various average weighted estimates. Significance of the corresponding unit quality indicators, incompleteness of the object description and control factors influence on the object took into account.The results of the research were got using the method of virtual experiment planning. They showed that the influencing parameters changes, the calculated levels and stability of the complex quality index essentially depend on the type of convolution. It was shown that under the priori uncertainty of the necessary convolution for the best representative choosing of the corresponding class of objects, the arithmetic average weighted estimate is the best for using.The obtained data can serve as a basis for an informed choice of the type of average weighted in the quality assessment of various objects and decision-making on rational levels of controlled factors.
TRANSFORMATION AND SCATTERING OF SURFACE WAVES ON THE ACOUSTIC LOAD TO ULTRASONIC EVALUATION AND MEASUREMENTS. Part 1. The boundary of acoustic contact is sliding
Authors: Baev A. R. , Panteleenko F. I. , Zakharenko V. V. , Razmyslovich G. I. , Lark K. G. , Gil N. N. 
Published: July 2018

for the enhancement and improvement of ultrasonic methods evaluation and measurements. The purpose of this work is to determine the influence of the geometric parameters of the acoustic load body and its position on the coefficients of reflection and propagation of the Stoneley and Rayleigh waves and to identify the possibility of using the results of the study for practical applications.Based on the analysis of the acoustic path and the experimental data, the relationship between the measured amplitude parameters and the coefficients of the propagation and reflection of surface waves, as well as the reflectivity of the contact region of the load body in the form of a prism through the sliding boundary, which reaches up to ≈ 32–34 дБ, is established. For the first time, the dependence of these coefficients on the inclination angle of one of the prism lateral faces in the range of 0 ± 45°, dimensionless thickness of the contact layer (0–0,05) and its orientation relative to the acoustic axis.It is established that these coefficients are mainly maximal when the prism is rectangular. The coefficient of reflectivity in the hard contact of bodies is more than an order of magnitude less, and the coefficients of wave propagation – comparable in magnitude. The prospects of using the results of the study to evaluate the quality of adhesion of materials during welding, soldering, gluing, detection of defects in hardto-reach places, as well as to determine the physical and mechanical properties of metals by the proposed method of creating a reference signal are shown.
PROBABILISTIC ANALYSIS OF DEPTH AND CARBONATION FRONT DEVELOPMENT IN CONCRETE OF MARINE STRUCTURES
Authors: Shalyi E. E. , Kim L. V. , Leonovich S. N. , Stepanova A. V. 
Published: July 2018

On the coast of the Russian Far East the climate is monsoon, which is most pro-nounced in the south and northeast waning. Seasonal change of oceanic and continental influence is reflected in the nature of the climate: summer is moderatelywarm and rainy, winter is cold and snowy. On Sakhalin winters are less severe than on the mainland. In Kamchatka, where the winters are milder, the influence of the continental monsoon less. In the southern part of Primorye snow is so small that there is in the rivers spring flood. In the north of the Amur region, Sakhalin, Kamchatka rainfall and snowpack increases. In the summer is dominated by southeast wind, which spread to the continent moist Pacific air. During the year, between the Pacific Ocean and the south of the Far East there is an intensive exchange of air masses. Seasonal change of air currents is determined by the thermal contrast between the continent and the ocean. During the year passes over the area to an average of 100 cyclones (3–6 per month during the cold period, and up to 3 – warm), which are ac-companied by increased wind, cloudy weather with precipitation, and in late summer and early au-tumn, typhoons observed outputs. Typhoons are accompanied by stormy winds reaching speeds of over 40 m / sec. and heavy rains. A wide variety of observed in the distribution of precipitation. The Chukchi-Anadyr area for the warm period falls to 200–250 mm in the north of the Sea of Okhotsk – 400–500 mm, in intermountain basins up to 250–300 mm. To the south the amount of precipitation increases to 500 to 600 mm in the Amur region and 900–1000 mm on the western slopes of Sikhote Alin. In the course of the annual maximum rainfall in the second half of the summer, but there are rainy June and September. No wonder that in such conditions, corrosion, material of hydraulic structures is most intense. Concrete and cement stone reinforced concrete structures exposed to corrosive attack, particularly the aggressive action of CO2 common acid gas, which is to neutralize the surface layer of concrete and the formation of the compounds that affect its properties. The article discusses the impact of the environment model south of the Far East, mainly due to the impact on hydraulic reinforced concrete structures of carbon dioxide in the environment, with subsequent corrosion of concrete and reinforcement.
CALCULATION OF A RECTANGULAR PLATE ON THE TWO-LAYER BASIS
Authors: Bosakov S. V. , Zinevich S. I. 
Published: July 2018

Operating experience of concrete with vigorous motion of heavy vehicles has shown that, despite the high strength concrete slabs themselves, they need a strong base. When concrete is close to the ground in it, as a result pushes elastically flex when the aisles plates vehicles accumulated residual deformation. Initially, under the plates formed cavity plate lose contact with the ground, and then these cracks. The increase in base strength increases the cost of the pavement. In this paper, a static analysis of rectangular plate on two-layer elastic foundation in the traditional setting. As the base, taken homogeneoussoils, with the upper and lower layer in the form of half-spaces. Considered plate loading variant symmetrical about two axes from the calculated external load wheels. The calculation is performed by B. N. Zhemochkina using symbolic mathematics package. When this plate was divided into 72 rectangular portion in the center of which was placed vertical brace, through which the elastic plate contact with a base. The resulting statically indeterminate system, calculated by the method of mixed structural mechanics, where efforts were taken for unknown in vertical connections, as well as linear and two angular displacements inputted pinching plate along the axis of symmetry. Coefficients of the unknowns related efforts B. N. Zhemochkina determined by the method described previously by one of the authors. The calculation of the vertical plate prepared surface displacements reactive voltage across the contact plate and an elastic base. The proposed approach can be used to find the optimal solutions to (sufficiently) base strength to the estimated vehicle as well as for calculations hinged precast concrete plates.
Role of Heme Oxygenases in Cardiovascular Syndromes and Co-morbidities
Authors: Haines David D. , Tosaki Arpad 
Published: July 2018

Cardiovascular Diseases (CVD), are the leading cause of human mortality worldwide and the focus of
the intensive investigation is to characterize their pathogenesis. This review examines contribution to CVD of
heme oxygenases (HOs), heat shock protein enzymes, comprising 3 isoforms: HO-1 (inducible), HO-2 (constitutively
expressed) and HO-3 (function presently undefined), which constitute a primary endogenous countermeasure
to oxidative tissue damage. Their role as CVD countermeasures is considered in the context of atherosclerosis,
consequences of which are the leading cause of CVD deaths and from which 5 major syndromes may develop,
namely: coronary artery disease and stroke, peripheral artery disease, kidney disease, cardiopulmonary disease
and cerebrovascular disease. Over 75% of CVD deaths result from Coronary artery disease and stroke, with
the severity of these conditions correlating with a systemic increase of the endogenous antioxidant bilirubin,
produced by HO degradation of heme. Peripheral artery disease, (PAD) resulting from constricted arteries of the
extremities is a painful and disabling condition, the severity of which correlates with elevated serum HO. Whether
this represents an adaptive response or the enzyme is a contributor to PAD, remains to be determined. CVD
symptoms, particularly hypertension, damage the vasculature and filtering structures of the kidneys and may be
ameliorated by HO inducers. Interestingly, constitutive renal expression of HO-2 indicates that the enzyme is
vital for healthy kidney function. Right ventricular hypertrophy and increased vascular resistance in blood vessels
of the lungs exhibit mutually reinforcing positive feedback to result in cardiopulmonary heart disease, with morbidity
and mortality resulting from associated inflammation and may be decreased with HO-1 inducers. Cerebrovascular
disease, a major CVD complication affecting brain vasculature, with resulting susceptibility to stroke,
maybe potently ameliorated by HO-1 inducers.

Conclusion:
Each of the six major categories of CVD exhibit features of pathogenesis that hold potential as future
therapeutic targets, for modulated heme oxygenase activity.
Virtual Screening, Molecular Modelling and Biochemical Studies to Exploit PF14_0660 as a Target to Identify Novel Anti-malarials
Authors: Raturi Vimee , Abhishek Kumar , Jana Subhashis , Bag Subhendu Sekhar , Trivedi Vishal 
Published: July 2018

Background:
Malaria Parasite relies heavily on signal transduction pathways to control
growth, the progression of the life cycle and sustaining stress for its survival. Unlike kinases,
Plasmodium&#039;s phosphatome is one of the smallest and least explored for identifying drug target
for clinical intervention. PF14_0660 is a putative protein present on the chromosome 14 of
Plasmodium falciparum genome.

Methods:
Multiple sequence alignment of PF14_0660 with other known protein phosphatase indicate
the presence of phosphatase motif with specific residues essential for metal binding, catalysis
and providing structural stability. PF14_0660 is a mixed &#945;/&#946; type of protein with several &#946; -sheet
and α-helix arranged to form βαβαβα sub-structure. The surface properties of PF14_0660 is conserved
with another phosphate of this family, but it profoundly diverges from the host protein tyrosine
phosphatase. PF14_0660 was cloned, over-expressed and protein is exhibiting phosphatase
activity in a dose-dependent manner. Docking of Heterocyclic compounds from chemical libraries
into the PF14_0660 active site found nice fitting of several candidate molecules.

Results:
Compound PPinh6, PPinh 7 and PPinh 5 are exhibiting antimalarial activity with an IC50
of 1.4 &#177; 0.2&#181;M, 3.8 &#177; 0.3 &#181;M and 9.4 ± 0.6&#181M respectively. Compound PPinh 6 and PPinh 7 are
inhibiting intracellular PF14_0660 phosphatase activity and killing parasite through the generation
of reactive oxygen species.

Conclusion:
Hence, a combination of molecular modelling, virtual screening and biochemical study
allowed us to explore the potentials of PF14_0660 as a drug target to design anti-malarials.
Metabolic Syndrome and Its Effect on the Brain: Possible Mechanism
Authors: Arshad Nurul ‘Ain , Lin Teoh Seong , Yahaya Mohamad Fairuz 
Published: July 2018

Background & Objective: Metabolic syndrome (MetS) is an interconnected group of
physiological, biochemical, clinical and metabolic factors that directly increase the risk of cardiovascular
disease, type 2 diabetes mellitus (T2DM) and mortality. Rising evidence suggests that MetS
plays a significant role in the progression of Alzheimer’s disease and other neurodegenerative diseases.
Nonetheless, the factors linking this association has not yet been elucidated. As we are facing an
increasing incidence of obesity and T2DM in all stages of life, understanding the association of MetS
and neurodegenerative diseases is crucial to lessen the burden of the disease.

Conclusion:
In this review, we will discuss the possible mechanisms which may relate the association
between MetS and cognitive decline which include vascular damages, elevation of reactive oxygen
species (ROS), insulin resistance and low-grade inflammation.
Амброксол у комплексному лікуванні хворих із гострими респіраторними захворюваннями
Authors: Duda O.K. , Boyko V.O. , Kotsiubailo L.P. , Konoplianik A.I. 
Published: July 2018

У статті описано інноваційні дані щодо оптимізації патогенетичної терапії в пацієнтів із гострими респіраторними захворюваннями з проявами трахеїту, бронхіту, ускладненими пневмонією в дорослих. Описано етіологічну структуру гострих респіраторних захворювань та стійкість до антибактеріальних препаратів. Показана роль амброксолу гідрохлориду в комплексному лікуванні хворих із гострими респіраторними захворюваннями з різними ускладненнями з боку дихальної системи. Встановлено, що використання амброксолу гідрохлориду позитивно впливає на основний етіологічний процес, зменшує термін стаціонарної стадії лікування через швидке припинення бактеріальної екскреції в середньому на 3,8 ± 0,7 дня у 75 % пацієнтів (р = 0,001).
Роль мотивації й оснащеності занять у вивченні психіатрії та наркології
Authors: Mishiyev V.D. , Grynevych Ye.G. , Omelyanovych V.Yu. , Makarenko S.M. 
Published: July 2018

Мета. Вивчення напрямків підвищення мотивації лікарів-слухачів в отриманні знань та вмінь за спеціальностями «психіатрія» і «наркологія». Матеріали та методи. Матеріал дослідження — лікарі, які проходили навчання на циклах післядипломної освіти (спеціалізації, передатестаційних, тематичного удосконалення) за спеціальностями «психіатрія» та «наркологія» на кафедрі загальної, дитячої, судової психіатрії і наркології у 2016 р. Методи дослідження: інформаційно-теоретичний, аналітичний, опитування (інтерв’ю, анкетування), спостереження, методи описової статистики. Результати. Важливим завданням викладача є розвиток навчально-пізнавальних мотивів слухачів циклів підвищення кваліфікації, що орієнтовані на засоби отримання та засвоєння знань і оволодіння професійними навичками. Формування соціальних мотивів, таких як обов’язок, відповідальність за життя, психічне здоров’я хворого, розуміння соціальної значущості глибоких знань із психіатрії і наркології на тлі заходів щодо підвищення інтересу до навчання є важливими завданнями у навчальному процесі на кафедрі загальної, дитячої, судової психіатрії і наркології. Висновки. Концептуальні методичні принципи, що підвищують інтерес до навчання, мають різний ранг у структурі мотивації лікарів-слухачів. Застосування методів і прийомів педагогічної герменевтики призводить до змін характеру пізнавальної діяльності з репродуктивного на креативний. Серед невербальних методів педагогічної герменевтики найбільша ефективність досягнення мети та підвищення інте­ресу до навчання встановлена при грі з готовими правилами, грі-імітації, грі-імпровізації. Актуальність реалізації загальних принципів педагогіки в навчальному процесі для слухачів різних циклів післядипломного навчання має значні відмінності.