bluuebunny/crossref_metadata_2025_split huggingface dataset:
Printing Cell Embedded Sacrificial Strategy for Microvasculature using Degradable DNA Biolubricant
Authors: Shi Jiezhong , Wan Yifei , Jia Haoyang , Skeldon Gregor , Jan Cornelissen Dirk , Wesencraft Katrina , Wu Junxi , McConnell Gail , Chen Quan , Liu Dongsheng , Shu Wenmiao 
Published: October 2024

AbstractMicrovasculature is essential for the continued function of cells in tissue and is fundamental in the fields of tissue engineering, organ repair and drug screening. However, the fabrication of microvasculature is still challenging using existing strategies. Here, we developed a general PRINting Cell Embedded Sacrificial Strategy (PRINCESS) and successfully fabricated microvasculatures using degradable DNA biolubricant. This is the first demonstration of direct cell printing to fabricate microvasculature, which eliminates the need for a subsequent cell seeding process and the associated deficiencies. Utilizing the shear‐thinning property of DNA hydrogels as a novel sacrificial, cell‐laden biolubricant, we can print a 70 μm endothelialized microvasculature, breaking the limit of 100 μm. To our best knowledge, this is the smallest endothelialized microvasculature that has ever been bioprinted so far. In addition, the self‐healing property of DNA hydrogels allows the creation of continuous branched structures. This strategy provides a new platform for constructing complex hierarchical vascular networks and offers new opportunity towards engineering thick tissues. The extremely low volume of sacrificial biolubricant paves the way for DNA hydrogels to be used in practical tissue engineering applications. The high‐resolution bioprinting technique also exhibits great potential for printing lymphatics, retinas and neural networks in the future.
Half‐Sandwich Ruthenium Complexes With N‐Phenylpicolinamide Ligands: Preparation and Catalytic Activity in Transamidation Reaction
Authors: Wang Zhi‐Jie , Luo Yu‐Zhou , Yao Zi‐Jian 
Published: October 2024

ABSTRACTA series of N,N‐chelate half‐sandwich ruthenium complexes based on N‐phenylpicolinamide ligands has been prepared with good yields through a facile route. These air and moisture stable N,N‐chelate half‐sandwich ruthenium complexes showed good catalytic efficiency in transamidation reactions between aromatic amines and amides under mild reaction conditions. A variety of secondary amides was obtained in high yields under open flask condition with broad substrates and good group tolerance. The excellent catalytic activity, broad substrate range, and mild reaction conditions make this catalytic system a potential candidate for industrial production. In addition, the structure of the prepared ruthenium complex has been confirmed by single crystal X‐ray diffraction.
Curing reactions, reaction kinetics, and latency of epoxy resin cured with L‐tryptophan and L‐tyrosine
Authors: Rothenhäusler Florian , Hüser Daniel , Ruckdaeschel Holger 
Published: October 2024

AbstractIn the research on amino acids as bio‐based curing agents for epoxy resins, L‐tryptophan and L‐tyrosine have emerged as promising alternatives. Understanding the curing reactions and reaction kinetics is crucial for designing an appropriate curing regime to tailor the mechanical properties of thermosets. This study provides a comprehensive analysis of the curing reactions, curing kinetics, and latency of epoxy resin cured with L‐tryptophan or L‐tyrosine in the presence of urea‐based accelerators. L‐tryptophan involves three distinct curing reactions, corresponding to its three functional groups, while data on L‐tyrosine as a curing agent is less definitive. The degree of cure can be reliably predicted using model‐free kinetics for all resin systems studied. Overall, the inclusion of accelerators facilitates rapid curing at elevated temperatures while maintaining adequate processability for up to four weeks of storage at room temperature.
Preparation of styrene‐phenylamine monomer copolymer nanospheres and its performance for stabilizing CO2 foam
Authors: Huang Jiaqi , Zhang Jian , Wang Xiujun , Huang Bo , Hua Zhao , Fang Shenwen 
Published: October 2024

AbstractImproving the stability of CO2 foam is a core concern in CO2 foam flooding oil recovery technology. Using hydrophobic nano‐SiO2 to enhance the stability of CO2 foam is a common approach, but hydrophobic nano‐SiO2 faces challenges, such as easy aggregation, difficult dispersion, and performance needs to improve. In this article, a novel dispersion of styrene‐phenylamine monomer copolymer (PSSN) nanosphere with primary amine groups on the surface was synthesized. The synthesis conditions of PSSN were optimized, and its performance for stabilizing CO2 foam was evaluated. The experimental results demonstrated that PSSN had better performance for stabilizing CO2 foam than that of hydrophobic nano‐SiO2 when using cocamidopropyl betaine (CAB) as the foaming agent. With the CAB concentration of 4000 mg/L and PSSN concentration of 100 mg/L in the brine having salinity of 8460 mg/L, the half‐life of CO2 foam at 90°C was 131 min, which was 43 min longer than that stabilized by hydrophobic nano‐SiO2 under the same conditions. This is for the first time that polystyrene microspheres with amine groups on the surface was used to stabilize CO2 foam. The study provides a new nanoparticle option for stabilizing CO2 foam.
Enhancing Burning Rate of Ammonium Nitrate by Ammonia Borane: Mechanism from Reactive Molecular Dynamics Simulation
Authors: Yu Yin , Jiang Jun , Ye Cai‐Chao , Ju Xue‐Hai 
Published: October 2024

AbstractThe development of ammonium nitrate (AN)/ammonia borane (AB) as a green propellant is crucial for their applicability in different engines. This study investigates the release patterns of small products, particularly nitrogen‐containing molecules, during the initial pyrolysis of AN/AB at low and high pressures using ReaxFF MD simulations. Compared with pure AN, the addition of AB gives the hybrid system enhanced reactivity, leading to faster decomposition and higher energy release. The results show that the consumption of AN in the S13 system (AB with a mass ratio of 12.6 %) is accelerated at 1.47 MPa. NO2 and NO are produced through HNO3 and NO3. At 6.89 MPa, AN exhibits the fastest decomposition rate in the S15 system. The high pressure enhances more reactions of NO with free radicals such as NH and accelerates the release of N2. As the percentage content of AB increases to 15.3 %, more H2O while more NO2 is generated. The effect of AB on the generation of radicals such as H2 and H, is analyzed. AB not only promotes the initial pyrolysis of AN but also accelerates the conversion of intermediates.
Elucidating the Photo‐Induced Electronic Structure and Mechanisms of ZnAl‐Layered Double Hydroxide: A DFT Study
Authors: Wang Yi , Li ZiXian , Liu Huijie , Dong Wenjing , Zhao Yufei , Liu Lihong 
Published: October 2024

AbstractLayered double hydroxides (LDHs) have been regarded as excellent catalysts for a variety of photocatalytic applications including the hydrogen production, carbon dioxide reduction, and nitrogen fixation, et al. The elucidation of the photocatalytic mechanism of LDH‐based photocatalysts under light irradiation, especially at the ultraviolet (UV) and deep ultraviolet (DUV) region, at the molecular level has remained elusive. In this study, the photo‐induced electronic structure of ZnAl‐LDH materials was investigated, and a comprehensive understanding of its underlying mechanism, both in the UV and DUV region, was gained using density functional theory (DFT) calculations. The UV and DUV regions exhibit distinct excitation characteristics, revealing the complex interactions between electrons and holes within the system. The DUV region significantly promotes electron transfer, indicating the potential application of LDH materials as a DUV catalysis material. This study elucidates the electron transfer kinetics in LDHs upon UV and DUV irradiation, thereby offering new perspective for the development of photocatalytic materials under different light region.
Simulated Exact Confidence Intervals: With Applications to Censored Exponential Reliability Data
Authors: Lindqvist Bo Henry , Taraldsen Gunnar 
Published: October 2024

ABSTRACTA method for constructing exact simulated confidence intervals is presented, valid for situations with both discrete and continuous observations. The idea of the method is to invert a data generating function, which needs not be monotone, and where special attention is taken when the data generating function contains jumps. The method is applied to obtain exact confidence intervals for certain types of censored data from exponential distributions. The censoring schemes under study are earlier treated in the literature, and a comparison to these approaches is considered. The connection to fiducial inference is discussed, and a difference in the paradigm of obtaining intervals for the parameter is studied.
Fruit and vegetable waste as a raw material for obtaining functional antioxidants and their applications: A review of a sustainable strategy
Authors: García‐González Adilson G. , Pasiano Rivas‐García  , Carlos Escamilla‐Alvarado  , Ramírez‐Cabrera Mónica A. , Paniagua‐Vega David , Uriel Galván‐Arzola  , Cano‐Gómez José J. , Escárcega‐González Carlos E. 
Published: October 2024

AbstractThe growing concern about environmental sustainability and increasing fruit and vegetable waste (FVW) generation have stimulated research into their potential valorization. This paper explores using this type of waste to obtain beneficial antioxidants in various fields of study. It is imperative to delve into the problems associated with FVW, shedding light on the staggering amounts generated and the environmental and economic challenges of waste disposal. The biochemical composition of FVW reveals the diverse array of components present, such as carbohydrates, proteins, lipids, vitamins, minerals, and of course antioxidants, which can be obtained through different extraction methods, depending on the conditions, the efficiency and the purpose that is required during the process of separation of these compounds from the organic matter. Antioxidants are compounds that can neutralize free radicals, which contributes to combating various conditions and diseases to promote and preserve human health. Several groups of antioxidants have been described, such as polyphenolic compounds in significant amounts in plant biomass as FVW. These antioxidants demonstrate benefits, efficacy and potential applications in industries like medicine, cosmetics, pharmaceuticals and functional foods. The valorization of FVW as a source of antioxidants presents a promising avenue for sustainable waste management and the production of natural antioxidants. This approach contributes to environmental preservation and promotes circular economy principles by transforming waste into valuable resources. This paper provides valuable insights into the vast potential of FVW valorization for antioxidant production and its application across diverse industries.
Accuracy of warm ischemia time measurement using a surgical intelligence software in partial nephrectomies: A validation study
Authors: Khandekar Archan , Porto Joao G. , Daher Jean C. , Freitas Pedro F. S. , Asselman Dotan , Suarez Maritza M. , Gonzalgo Mark L. , Parekh Dipen J. , Punnen Sanoj 
Published: October 2024

AbstractObjectivesThe objectives of this study are to compare the accuracy of warm ischemia times (WITs) derived by a surgical artificial intelligence (AI) software to those documented in surgeon operative reports during partial nephrectomy procedures and to assess the potential of this technology in evaluating postoperative renal function.Patients and methodsA surgical AI software (Theator Inc., Palo Alto, CA) was used to capture and analyse videos of partial nephrectomies performed between October 2023 and April 2024. The platform utilized computer vision algorithms to detect clamp placement and removal, enabling precise WIT measurement. Expert‐reviewed surgical videos served as the ground truth. Platform‐derived WITs were compared to those in surgeon operative reports using paired‐sample t‐tests. Additionally, we analysed the correlation between platform‐derived WITs and postoperative creatinine levels extracted from electronic health records (EHRs) integrated via health level seven (HL7) messaging protocols.ResultsOf 64 eligible cases, 61 were included in the final analysis. Platform‐derived WITs were within 1 min of the ground truth in all procedures, within 30 s in 97%, and within 10 s in over 80%. The mean difference between platform‐derived WITs and ground truth was 8.3 s, significantly lower than the 2.45 min difference for operative reports (p < 0.001). No significant correlation was found between platform‐derived WIT and postoperative creatinine changes, aligning with the view that WIT may not independently determine postoperative renal function. Although not the primary goal of this study, significant correlations were observed between WIT, tumour size and RENAL score.ConclusionThis study demonstrates the high accuracy of a surgical intelligence platform in measuring WIT during partial nephrectomies. The findings support the use of AI‐based surgical time measurement for precise intraoperative documentation and highlight the potential of integrating these data with EHRs to advance research on surgical outcomes.
AIEE—Active Green Fluorescence Imaging Technique for Latent Fingerprint Application
Authors: Purushothaman Palani , Nishanthi S. , Induja B. , Umabharathi P. S. , Sethupathi M. , Karpagam Subramanian 
Published: October 2024

ABSTRACTLatent fingerprint imaging is a crucial tool for national security and crime recognition, requiring environmentally sustainable, nontoxic materials. To address this need, we have developed a green fluorescence‐emitting material, THCHO, that binds effectively to latent fingerprints, enabling clear, high‐resolution visualization. The solution produces strong green fluorescence that highlights fingerprint imprints with exceptional detail and contrast. The material is applicable across various substrates, making it efficient for on‐site visualization. The synthesized organic conjugated material THCHO rapidly visualizes precise fingerprint substructures within 5 s using a simple spray method. It maintains high contrast and low interference across different substrates, such as glass, aluminum foil, plastic, and ironware, even in diverse backgrounds. Additionally, the THCHO material demonstrates high stability, retaining its fluorescence imaging capabilities for up to 35 days and after water washing. This is the first report of using a conjugated organic thiophene material for latent fingerprint fluorescence imaging, suggesting potential applications in other fields.
Inhibition Control by Continuous Extractive Fermentation Enhances De Novo 2‐Phenylethanol Production by Yeast
Authors: Brewster Alessandro , Oudshoorn Arjan , van Lotringen Marion , Nelisse Pieter , van den Berg Emily , Luttik Marijke , Daran Jean‐Marc 
Published: October 2024

ABSTRACTCurrent microbial cell factory methods for producing chemicals from renewable resources primarily rely on (fed‐)batch production systems, leading to the accumulation of the desired product. Industrially relevant chemicals like 2‐phenylethanol (2PE), a flavor and fragrance compound, can exhibit toxicity at low concentrations, inhibit the host activity, and negatively impact titer, rate, and yield. Batch liquid‐liquid (L‐L) In Situ Product Removal (ISPR) was employed to mitigate inhibition effects, but was not found sufficient for industrial‐scale application. Here, we demonstrated that continuous selective L‐L ISPR provides the solution for maintaining the productivity of de novo produced 2PE at an industrial pilot scale. A unique bioreactor concept called “Fermentation Accelerated by Separation Technology” (FAST) utilizes hydrostatic pressure differences to separate aqueous‐ and extractant streams within one unit operation, where both production and product extraction take place ‐ allowing for the control of the concentration of the inhibiting compound. Controlled aqueous 2PE levels (0.43 ± 0.02 g kg−1) and extended production times (>100 h) were obtained and co‐inhibiting by‐product formation was reduced, resulting in a twofold increase of the final product output of batch L‐L ISPR approaches. This study establishes that continuous selective L‐L ISPR, enabled by FAST, can be applied for more economically viable production of inhibiting products.
Effects of Goreisan in the Perioperative Period of Subthalamic Deep Brain Stimulation in Parkinson's Disease
Authors: Kajikawa Hiroyuki , Matsuura Keita , Ii Yuichiro , Tabei Ken‐ichi , Nakamura Naoko , Ishikawa Hidehiro , Nishiguchi Yamato , Matsuda Kana , Kagawa Ken , Ichikawa Naoki , Araki Tomohiro , Shindo Akihiro 
Published: October 2024

ABSTRACTIntroductionPatients with Parkinson's disease (PD) may benefit from deep brain stimulation (DBS). Perifocal brain edema sometimes occurs after DBS surgery, but it is transient and does not affect the final prognosis. Transient deterioration of cognitive function has been reported in patients with frontal edema in the first postoperative week. This study aimed to investigate the effect of Goreisan in preventing edematous changes after DBS and determine the influence of edema on cognition.MethodsWe included 29 patients with PD who underwent bilateral subthalamic nucleus (STN) DBS and who were divided into 2 groups: those using (11 patients) and those not using Goreisan (18 patients). At 1 week postoperatively, all patients underwent magnetic resonance imaging. We measured the volume of edema either in the frontal white matter or STN on fluid‐attenuated inversion recovery (FLAIR) images. Finally, brain edema, motor function, and cognitive function were compared between the groups with and without Goreisan.ResultsIn the FLAIR image 1 week postoperatively, the average postoperative frontal subcortical edema (FE) volume of the group with Goreisan was significantly lower than that without Goreisan (2249 ± 2186 mm3, 6261 ± 7213 mm3, respectively, p = 0.023). Multivariate analysis with age, preoperative Mini‐Mental State Examination (MMSE) score, FE, and peri‐STN edema (SE) as factors, and MMSE at 1 week postoperatively as the dependent variable showed that preoperative MMSE score and SE were significant as associated factors.ConclusionsFE after DBS surgery may be alleviated using Goreisan. SE and preoperative MMSE scores were associated with MMSE scores 1 week postoperatively.Trial RegistrationNot applicable
Lessons to learn from pilot studies in clinical trials: The example of a trauma‐focused treatment for female survivors of intimate partner violence
Authors: Sánchez‐Ferrer Silvia , Antón Ana A. , Miguel‐Alvaro Alejandro , Crespo María 
Published: October 2024

AbstractBackgroundResearch on pilot studies is scarce, despite their importance for the development of effective clinical trials. There is a lack of work addressing the process, limitations and strategies derived from these studies. This gap is even more evident in research studying targeted populations, such as victims of intimate partner violence (IPV), who present specific difficulties, such as high dropout rates, or require the application of challenging treatments, such as trauma‐focussed exposure therapy.AimThis paper describes a pilot study (PS) implemented as a preliminary step in the development of a clinical trial (CT), in which a trauma‐focussed treatment for survivors of IPV with post‐traumatic symptomatology was applied. The problems identified in the PS and the solutions that were implemented in the CT are described. Additionally, comparisons between the PS and CT with respect to participant adherence to treatment and satisfaction, as perceived by the participants and the therapist, are analysed.ResultsResults indicate that satisfaction with the treatment was high in both studies; dropouts showed a significant decrease in the CT (25% in CT vs. 75% in the PS; p = .028), while group cohesion increased.ConclusionsIt is concluded that conducting pilot studies allows adapting treatments to the study population, which seems to increase the quality of clinical trials, subsequently improving the evidence of psychological interventions.
“It Can't Just Be the Younger People”: Exploring Young Activists' Perspectives on Intergenerational Tensions and Solidarities for Climate Justice
Authors: Trott Carlie D. 
Published: October 2024

ABSTRACTYouth activism for climate justice is inherently intergenerational. Fundamentally, young activists demand urgent action by today's adult power‐holders for the security and well‐being of their own and future generations. Despite intergenerationality being core to the movement, few studies with young activists have explored their views and experiences of intergenerational relations and tensions and how to advance intergenerational solidarities for climate justice. Addressing these critical topics, the present study used in‐depth interviews with young activists (ages 15–17) in the climate justice movement across the US. Themes generated through reflexive thematic analysis centre on: (1) youths' adoption of “next generation” and “last generation” identities, respectively emphasising the heightened climate risks faced by their own and future generations, and the closing window of opportunity to prevent catastrophic climate breakdown; (2) their experiences of hostile and benevolent adultism; and (3) the need for adults to listen to, take seriously, centre, amplify, and—most importantly—respond to youths' demands. They urge adults, particularly those in powerful positions, to use their age‐based privilege, political enfranchisement, material resources, professional status, and decision‐making authority to uplift young people's voices and tangibly advance climate justice through solidarity‐driven intergenerational partnerships and action. Implications for youth‐centred research and policy are discussed.
A case report of hepatic subcapsular hematoma: Newborn with an autoimmune hemolytic condition
Authors: Li Yunxin , Wang Aijie , Huang Ranran , Zhang Guowei 
Published: October 2024

Key Clinical MessageWe report a case of hepatic subcapsular hematoma in a newborn baby detected with an autoimmune hemolytic condition due to ABO incompatibility. Magnetic resonance imaging could be helpful in differentiating hepatic subcapsular hematoma from other abdominal masses.
Synthesis of Dibenzoazulene Derivatives via Pd‐Catalyzed (3+2) Alkyne Annulation of Dibenzosuberenone
Authors: Ma Zhuangzhuang , Qin Liyuan , Shangguan Zhichun , Shu Yilin , Ma Junlong , Liang Qi , Li Cheng , Zhang Guanxin , Zhang Xi‐Sha , Duan Zheng , Zhang Deqing 
Published: October 2024

AbstractNon‐benzenoid PAHs with pentagon/heptagon pairs have unique electronic structures and promising opto‐electronic properties. However, the construction of pentagon/heptagon pair units in these PAHs is challenging. Herein, we developed a Pd‐catalyzed (3+2) alkyne annulation reaction of heptagons, and constructed heptagon/pentagon pairs. The substrate scope is wide and the yield is good to moderate. A series of dibenzoauzlene derivatives were synthesized and their opto‐electronic properties were systematically studied by UV‐vis absorption and cyclic voltammetry. In addition, the dibenzoazulene derivative was further transformed to tropylium cation and tropyl radical, which showed bathochromic shifted absorption and switched aromaticity.