bluuebunny/crossref_metadata_2025_split huggingface dataset:
Guanine content of microRNAs is associated with their tumor suppressive and oncogenic roles in lung and breast cancers
Authors: Cohen Amit , Burgos-Aceves Mario Alberto , Smith Yoav 
Published: January 2019

AbstractBackgroundmicroRNAs (miRNAs, miRs) are small noncoding RNAs that negatively regulate gene expression at the post-transcriptional level and fine-tune gene functions. A global repression of miRNAs expression in different types of human tumors, after exposure to cigarette-smoke, or to the hormone estrogen, have been shown to be associated with guanine (G) enrichment in the terminal loops (TLs) of their precursors.Methodswe integrated the G content of miRNA mature forms and precursor miRNA TLs with their described function in the literature, using the PubMed database. Gene Ontology term analysis was used to describe the pathways in which the G-enriched miRNA targets are involved.Resultswe show here an association between the relative G enrichment of precursor miRNAs TLs and their tendency to act as tumor suppressor miRs in human lung and breast cancers. Another association was observed between the high G content of the miRNAs 5-mature forms and their tendency to act as oncomiRs.Conclusionsthe results support previous findings showing that the G sequence content is an important feature determining miRNA expression and function, and open the way for future cancer investigations in this direction.
Yes, has no meaning if you can’t say no: consent and crime in the chemsex context
Authors: Morris Stephen 
Published: January 2019

Purpose
The title of this paper is a statement made by a man at the end of his treatment following conviction for several sexual offences. It is powerful in conveying a simple and accurate meaning of consent. Legally, consent is not complicated and can be simply defined as: permission for something to happen or agreement to do something. The context of consent, however, is complicated and complex none more so than when it becomes an issue within chemsex. If we are to gain a full appreciation of consent-related complexity, we must also gain an understanding of the wider picture concerning chemsex and crime. The purpose of this paper is to provide that wider picture. With the exception of breaching of drug-related law, not all men who engage in chemsex are committing offences but, as we are discovering, a not insignificant percentage are and this needs to be cause for concern.

Design/methodology/approach
This study is a review and a personal perspective of the development of a criminal justice response to crime within the chemsex context.

Findings
This was a personal viewpoint, not a research project; therefore, there were no definitive findings.

Originality/value
This paper addresses lack of awareness within the criminal justice system in relation to chemsex, and the associated vulnerabilities. This work is original because there is a shortage of published work on the rise in chemsex-related crimes.
A framework for developing employer’s disability confidence
Authors: Lindsay Sally , Leck Joanne , Shen Winny , Cagliostro Elaine , Stinson Jennifer 
Published: January 2019

PurposeMany employers lack disability confidence regarding how to include people with disabilities in the workforce, which can lead to stigma and discrimination. The purpose of this paper is to explore the concept of disability confidence from two perspectives, employers who hire people with a disability and employees with a disability.Design/methodology/approachA qualitative thematic analysis was conducted using 35 semi-structured interviews (18 employers who hire people with disabilities; 17 employees with a disability).FindingsThemes included the following categories: disability discomfort (i.e. lack of experience, stigma and discrimination); reaching beyond comfort zone (i.e. disability awareness training, business case, shared lived experiences); broadened perspectives (i.e. challenging stigma and stereotypes, minimizing bias and focusing on abilities); and disability confidence (i.e. supportive and inclusive culture and leading and modeling social change). The results highlight that disability confidence among employers is critical for enhancing the social inclusion of people with disabilities.Originality/valueThe study addresses an important gap in the literature by developing a better understanding of the concept of disability from the perspectives of employers who hire people with disabilities and also employees with a disability.
The Trades Union Congress 150 years on
Authors: Simms Melanie , Holgate Jane , Roper Carl 
Published: January 2019

PurposeThe purpose of this paper is to reflect on how the UK’s Trade Union Congress, in the 150th year of its formation, has been responding to the significant changes in the labour market, working practices and union decline. The paper considers Trades Union Congress (TUC) initiatives to recruit and organise new groups of workers as it struggles to adapt to the new world of work many workers are experiencing. Although the paper reviews progress in this regard it also considers current and future challenges all of which are becoming increasingly urgent as the current cohort of union membership is aging and presents a demographic time bomb unless new strategies and tactics are adopted to bring in new groups of workers – particularly younger workers.Design/methodology/approachThis is a review paper so it mainly draws on writings (both academic and practitioner) on trade union strategy and tactics in relations to organising approaches and in particularly the TUC’s initiatives from the period of “New Unionism” onwards.FindingsThe authors note that while unions have managed to retain a presence in workplaces and industries where they membership and recognition, there has, despite a “turn to organising” been less success than was perhaps hoped for when new organising initiatives were introduced in 1998. In order to expand the bases of organisation into new workplaces and in new constituencies there needs to be a move away from the “institutional sclerosis” that has prevented unions adapting to the changing nature of employment and the labour market restructuring. The paper concludes that in order to effect transformative change requires leaders to develop strategic capacity and innovation among staff and the wider union membership. This may require unions to rethink the way that they operate and be open to doing thing radically different.Originality/valueThe paper’s value is that it provides a comprehensive overview of the TUC’s role in attempting to inject an organising culture with the UK union movement by drawing out some of the key debates on this topic from both scholarly and practitioner writings over the last few decades.
Fostering creativity and communicative soft skills through leisure activities in management studies
Authors: Mareque Mercedes , de Prada Creo Elena , Gonzalez-Sanchez Maria Beatriz 
Published: January 2019

Purpose
The purpose of this paper is to gain insight into the way leisure activities and soft skills relate to creativity in higher education. It determines which activities have a positive impact on the student body’s overall education. Previous research evidences the relationship between specific leisure activities and creativity performance in several scenarios. Our work applies a broad range of these leisure activities to find results within our own specific student population.

Design/methodology/approach
The methodology is based on a survey of 303 Spanish students in Business Administration and Tourism. The study uses two instruments to measure the creativity of students, the Runco Ideational Behavior Scale (RIBS) and a three-dimensional construct that measures divergent thinking (originality, fluency and flexibility).

Findings
The results reveal that the average for creativity is higher for those students participating in some of the activities proposed. A positive correlation was also observed between the number of leisure activities and the creativity measures analysed. This confirms that students participating in more leisure activities display higher levels of creativity. Finally, the results display that the vast majority of students are involved in some type of activity, but two of the interpersonal skills that companies appreciate the most (reading and writing) are performed by very few students. This is especially the case of writing.

Originality/value
This study contributes to the pedagogical strategies that can be used in universities to motivate practising leisure activities as a mean of fostering creativity. It is important to note that the involvement of students in leisure activities can benefit from their integration into the labour market.
Development of the Psychologist and Counsellor Self-Efficacy Scale
Authors: Watt Helen M.G. , Ehrich John , Stewart Sandra E. , Snell Tristan , Bucich Micaela , Jacobs Nicky , Furlonger Brett , English Derek 
Published: January 2019

PurposeThe purpose of this paper is to develop a professional self-efficacy scale for counsellors and psychologists encompassing identified competencies within professional standards from national and related international frameworks for psychologists and counsellors.Design/methodology/approachAn initial opportune sample of postgraduate psychology and counselling students (n=199) completed a ten-minute self-report survey. A subsequent independent sample (n=213) was recruited for cross-validation.FindingsA series of exploratory analyses, consolidated through confirmatory factor analyses and Rasch analysis, identified a well-functioning scale composed of 31 items and five factors (research, ethics, legal matters, assessment and measurement, intervention).Originality/valueThe Psychologist and Counsellor Self-Efficacy Scale (PCES) appears a promising measure, with potential applications for reflective learning and practice, clinical supervision and professional development, and research studies involving psychologists’ and counsellors’ self-perceived competencies. It is unique in being ecologically grounded in national competency frameworks, and extending previous work on self-efficacy for particular competencies to the set of specified attributes outlined in Australian national competency documents. The PCES has potential utility in a variety of applications, including research about training efficacy and clinical supervision, and could be used as one component of a multi-method approach to formative and summative competence assessment for psychologists and counsellors. The scale may be used to assess students’ perceived competencies relative to actual competency growth against national standards, and to identify trainees’ and practitioners’ self-perceived knowledge deficits and target areas for additional training.
Working from home: characteristics and outcomes of telework
Authors: Nakrošienė Audronė , Bučiūnienė Ilona , Goštautaitė Bernadeta 
Published: January 2019

PurposeThe purpose of this paper is to investigate the relationships between theoretically grounded telework factors and various individual and organizational outcomes of telework (overall satisfaction with telework, perceived advantages of telework, career opportunities and self-reported productivity).Design/methodology/approachBased on a literature review, ten telework factors that may affect individual and organizational telework outcomes were identified and empirically tested using the survey data of 128 teleworkers exercising different telework intensity and representing various sectors of the economy.FindingsThe bundle of theoretically selected variables explained a significant part of the variance of telework outcomes. Reduced communication with co-workers, supervisor’s trust and support, suitability of the working place at home were found to be the most important telework factors impacting different telework outcomes. Higher self-reported productivity was related to reduced time in communicating with co-workers, a suitable working place at home and the possibility to take care of family members when teleworking.Practical implicationsThis study provides insights about the management of telework in organizations by highlighting the factors that promote the satisfaction, productivity and perceived career opportunities of teleworkers.Originality/valueThis paper challenges the results of previous research on the factors related with telework and its outcomes. Based on the job demands-resources theory, the authors identified the factors that serve as resources in generating positive telework outcomes, and the factors increasing job demands and reducing satisfaction with telework.
Ethnic diversity management in France: a multilevel perspective
Authors: Hennekam Sophie , Bacouel-Jentjens Sabine , Yang Inju 
Published: January 2019

Purpose
The purpose of this paper is to present a case study of the multilevel factors that influence the way in which an organization approaches ethnic diversity management in France. Syed and Özbilgin’s (2009) relational framework was adopted to understand and contextualize ethnic diversity management in a car manufacturing company in France.

Design/methodology/approach
In total, 37 semi-structured in-depth interviews with employees of different hierarchical levels in a French organization have been conducted and analyzed using the Gioia method.

Findings
The findings show that the lack of clear laws and the universal citizenship model on macro-level coupled with the gendered industry and superficial engagement with ethnic diversity on meso-level overlooks the difficult situation of ethnic minorities in the workplace, especially women. However, the findings also stress that it is on individual level that resilience and agency can be expressed, which means that despite the perceived barriers on societal and organizational level, ethnic minorities are motivated to improve the way they are treated in organizations.

Originality/value
Ethnic minorities are an understudied dimension of diversity management in organizations. The findings underscore the importance of the intersection of ethnicity and gender as this affects the career development possibilities and daily work experience of ethnic minority women.
Strategic IT management: how companies can benefit from an increasing IT influence
Authors: Reichstein Christopher 
Published: January 2019

PurposeThe purpose of this paper is to analyze the value of a strong decision-making information technology (IT) influence within organizations. Although research and managerial practice has repeatedly shown the importance of IT departments within firms and has commented on the influence of IT departments on business performance, prior research has still no evidence about the value of a strong decision-making IT influence yet.Design/methodology/approachTo prove the influence of the IT department within the company, this study identifies and operationalizes a formative construct determined by four main specifics of the IT department: IT department size, IT department value assessment, IT experience of the top management and degree of digitization. A questionnaire was used to collect the data of 124 experts from companies that could be assigned mainly to the sectors manufacturing, trade as well as information and communication. The data were analyzed using exploratory and confirmatory factor analyses. Further, partial least squares structural equation model (PLS-SEM) was used to test the proposed model.FindingsThe results show that both investments in the size of the IT department as well as in top managers with IT experience, and a high degree of digitization in a company positively influence the role of the IT department. It also shows that a higher general appreciation of the IT department goes hand in hand with a higher influence of IT in the company. The measures are significant as companies, which do have an influential IT department, actually have higher monetary as well as non-monetary business performances.Practical implicationsThe study is aimed equally at science and practice, as it provides information on the extent to which more importance should be attached to IT management in the future and what organizational adjustments need to be made.Originality/valueDespite the ongoing discussions on the importance of IT management for business performance, no existing studies have delivered evidence that there is a significant direct link between the decision-making influence of IT and the extent of corporate performance. The present work therefore has two objectives. The theoretical goal is to clarify the impact of the IT department on business performance and to identify the factors that make up an influential IT department. The practical objective of the research is to provide recommendations on how firms could establish or expand the IT department.
Buyer-supplier relational paradigm in internationalization process
Authors: Saleh Md Abu , Ali M. Yunus , Quazi Ali , Blackman Deborah 
Published: January 2019

PurposeThe purpose of this paper is to explore international buyer–supplier relationships in an emerging developing country context. The study examines a number of factors derived from internationalization process (IP) theory and their impacts in a novel research setting. The relational variables of trust and commitment, and their drivers, are integrated into a model examining importers’ perspectives of their supplier relationships.Design/methodology/approachThis study applied a sequential methodological approach. Initially, a conceptual framework was developed from qualitative research and then quantitatively validated using structural equation modeling (SEM). The data for this study were collected conducting in-depth interviews and survey questionnaires. For empirical validation, the SEM technique was applied to assess the proposed model.FindingsImporting firm managers perceived that the commitment of their suppliers bolstered their trust in the relationship, this contrasts with the conventional contention of a reverse relationship. The findings confirm cultural similarity facilitates communication, leading to increased knowledge and experience of importers, thereby contributing to an enhanced commitment to build trust in the relationship.Practical implicationsThe conceptual framework developed in this study provides a direction to manage and enhance understanding of IP and relationship outcome. The findings have strategic implications for practicing managers in developing and supporting their importer–foreign supplier relationships.Originality/valueThis study is unique in assessing as well as validating key constructs of IP theory in an international exchange (importer–supplier) relationship. The study offers completely a new insight in relation to applying IP theory’s relational perspectives.
The effect of the JOBS act on analyst coverage of emerging growth companies
Authors: Precourt Elena 
Published: January 2019

PurposeThe purpose of this paper is to examine the section of the Jumpstart Our Business Startups (JOBS) Act related to information dissemination by sell-side security analysts. The paper analyzes how the abolishment of the quiet period requirements for emerging growth companies (EGCs) changes the analyst initiation timing and market expectation of and reaction to the issuance of the analyst recommendations.Design/methodology/approachThis paper considers the effect of the abolishment of the quiet period requirements on analyst coverage initiations for EGCs with IPOs between January 2006 and December 2015 using regression analyses and probability models.FindingsThe results confirm the current anecdotal and empirical evidence that a shorter, de facto, quiet period exists. Analyst issue stronger average ratings for EGCs than for similar firms with IPOs before the JOBS Act. EGCs with initiations from multiple analysts also experience stronger positive market reaction than the firms with initial offerings before the JOBS Act. The market seems to anticipate which EGCs will have initiations and particularly which EGCs will have initiations from multiple analysts. The investors, however, do not fully anticipate the strength of actual recommendations.Practical implicationsThis paper is important for researchers, practitioners and policy-makers to understand how analysts impact the financial markets, how timing of analyst initiations affects stock prices of EGCs and what firm characteristics play a role in securing analyst coverage shortly after initial offerings.Originality/valueThis paper adds to the emerging literature on consequences of and changes brought by the JOBS Act. Specifically, this paper extends the limited literature on analyst initiations issued for firms with IPOs following the JOBS Act, timing of those initiations and magnitude of the market’s response to the initiations.
Cultivating creative workplaces through mindfulness
Authors: Byrne Ellen Keithline , Thatchenkery Tojo 
Published: January 2019

Purpose
The purpose of this paper is to examine how mindfulness training impacts creativity with individuals in a workgroup and propose a methodology for future research.

Design/methodology/approach
The methodology developed drew on existing laboratory-based research and applied those designs in a real-world application. The sample participants were from a mid-sized real estate firm that included ten realtors and support staff, six in the treatment group and four in the comparison group. The study took place over 16 weeks where pre-test and post-test mindfulness and creativity assessments were administered. A five-week mindfulness training was conducted with the treatment group and following the post-tests with the comparison group.

Findings
Results indicated that the mindfulness training positively impacted creativity in the moment and over time. There was evidence that the mindfulness training positively impacted an individual’s level of attention and awareness in daily activities which is likely to influence creative outcomes in organizational settings.

Research limitations/implications
This study shows that it is possible to design experimental studies in work settings and contribute to the empirical research about mindfulness despite the widely held perception about scarcity of time and lack of access to do such research. The findings also build on existing literature and address some of the gaps in current research. The most notable limitation relates to the small sample size.

Practical implications
The finding affirms that even a short but consistent practice of mindfulness in organizations can lead to a measurable increase in creativity.

Originality/value
This empirical study adds value to existing literature by expanding laboratory-based methodology to a practical application. One of the unique aspects of this research relates to the sample population. This research was conducted with an intact workgroup and translates the insights gained from laboratory research to a potential benefit for an organization by applying a version of this methodology to enhance its workgroup creativity.