bluuebunny/crossref_metadata_2025_split huggingface dataset:
Measuring Sense of Community Responsibility in Community‐Based Prevention Coalitions: An Item Response Theory Analysis
Authors: Treitler Peter C. , Andrew Peterson N. , Howell Tyriesa Howard , Powell Kristen Gilmore 
Published: September 2018

AbstractResearch on sense of community (SOC) has traditionally been approached from a resource perspective. Recently, however, research on the experience of SOC has evolved to include a related but distinct construct of sense of community responsibility (SOC‐R), or feelings of accountability for the well‐being of a community. This study applied item response theory to examine the psychometric properties of a SOC‐R scale used in an evaluation of community‐based substance abuse prevention coalitions. Data were collected in 2017 from coalition members (analytic sample = 309) in the northeastern United States. Findings indicate that the scale was reliable, unidimensional, and functioned well, particularly at low and moderate levels of the construct. The addition of two items intended to capture higher levels of the construct improved the scale's functioning at higher levels of SOC‐R. The adapted SOC‐R scale was also shown to have moderately strong relationships with conceptually relevant variables, including SOC, coalition participation, number of roles performed in the coalition, and engagement in community action activities. These findings provide empirical evidence to support the reliability and validity of the SOC‐R scale, and have critical implications for our conceptualization of the SOC construct, its measurement, and for the evaluation of community‐based prevention interventions.
A prospective, randomized, single‐blinded trial for improving health outcomes in rhinology by the use of personalized video recordings
Authors: Sharma Saurabh , McCrary Hilary , Romero Erin , Kim Alexander , Chang Eugene , Le Christopher H 
Published: September 2018

BackgroundClear patient‐physician communication is critical in improving patient compliance, outcomes, and satisfaction. However, constraints of shortened clinic visits, patient anxiety, and poor recall can cause significant barriers to effective communication. We hypothesized that the ability to view patient‐physician counseling videos at home would improve health outcomes.MethodsPatients in a tertiary rhinology clinic were enrolled into a single‐blinded prospective study after obtaining institutional review board (IRB) approval and informed consent. All enrollees had a short summary of their clinical encounter video‐recorded with a tablet using Medical Memory, a Health Insurance Portability and Accountability Act (HIPAA)‐compliant software system. Patients were randomized to receive access to their videos by our research coordinator, and outcomes included questionnaires at the first postoperative visit to assess patient recall and satisfaction.ResultsA total of 101 patients were enrolled. Half of those with video access watched the video at least once, on average 3.44 times. Of those without access, 90% would have liked the option. Those with video access had a higher percentage of correct answers to questions regarding surgical risk and extent of surgery; however, there was no significant difference between the 2 groups.ConclusionOur results show that patients in both groups were enthusiastic about this technology and often shared their videos with family and friends. Video‐recordings of physician‐patient encounters may be a possible solution to improve physician‐patient communication.
Phenolische Bausteine für die Assemblierung von Funktionsmaterialien
Authors: Rahim Md. Arifur , Kristufek Samantha L. , Pan Shuaijun , Richardson Joseph J. , Caruso Frank 
Published: September 2018

AbstractPhenolische Materialien sind seit langem für ihre Verwendung in Farbtinten, in Holzbeschichtungen und zur Ledergerbung bekannt. In letzter Zeit ist jedoch ein wachsendes Interesse an der Entwicklung moderner Werkstoffe aus phenolischen Bausteinen zu verzeichnen. Die intrinsischen Eigenschaften von phenolischen Verbindungen, wie Metallchelat‐Bildung, Wasserstoffbrücken, pH‐Ansprechverhalten, Redoxpotentiale, Radikalfänger, Polymerisation und Lichtabsorption, haben sie zu einer eigenständigen Klasse von Strukturelementen für die Synthese von funktionellen Materialien gemacht. Aus Phenolverbindungen hergestellte Materialien behalten viele ihrer nützlichen Eigenschaften, oft mit synergistischen Effekten bei Anwendungen, die von der Katalyse bis zur Biomedizin reichen. Dieser Aufsatz gibt einen Überblick über die verschiedenen funktionellen Materialien, die aus natürlichen und synthetischen phenolischen Bausteinen hergestellt werden können, und über ihre Anwendungen.
The Electrochemical Sodiation of FeSb2: New Insights from Operando 57Fe Synchrotron Mössbauer and X‐Ray Absorption Spectroscopy
Authors: Fehse Marcus , Bessas Dimitrios , Darwiche Ali , Mahmoud Abdelfattah , Rahamim Guy , La Fontaine Camille , Hermann Raphael P. , Zitoun David , Monconduit Laure , Stievano Lorenzo , Sougrati Moulay T. 
Published: September 2018

AbstractOperando Sb K‐edge X‐ray absorption spectroscopy and 57Fe Synchrotron Mössbauer Spectroscopy, used for the first time in the field of operando energy storage materials, assisted by operando magnetic measurements, were combined to clarify the role of iron and antimony in the electrochemical reaction mechanism of FeSb2 as negative electrode material for sodium‐ion batteries (SIB). Both datasets were analyzed using an innovative chemometric approach involving principal component analysis (PCA) and multivariate curve resolution – alternating least square analysis (MCR‐ALS) yielding new insights on the sodiation reaction. Our findings show that the reaction of Na with FeSb2 during discharge leads to the formation of Na3Sb along with superparamagnetic Fe amorphous nanoparticles which contain small amounts of Sb dissolved in their lattice. During the following desodiation, the pristine material FeSb2 is not recovered while iron nanoparticles grow in size, and continue growing also along the following discharge. Even though such iron nanoparticles remain electrochemically inactive, they play a key role in the reduction and stabilization of the polarization as well as in the reversibility of the electrochemical sodiation of antimony.
Observations below multiple lower limits of quantification: How to estimate the mean and variance
Authors: Berger Tanja , Hilgers Ralf‐Dieter , Heussen Nicole 
Published: September 2018

AbstractMultiple lower limits of quantification (MLOQs) result if various laboratories are involved in the analysis of concentration data and some observations are too low to be quantified. For normally distributed data under MLOQs there exists only the multiple regression method of Helsel to estimate the mean and variance. We propose a simple imputation method and two new maximum likelihood estimation methods: the multiple truncated sample method and the multiple censored sample method. A simulation study is conducted to compare the performances of the newly introduced methods to Helsel's via the criteria root mean squared error (RMSE) and bias of the parameter estimates. Two and four lower limits of quantification (LLOQs), various amounts of unquantifiable observations and two sample sizes are studied. Furthermore, the robustness is investigated under model misspecification. The methods perform with decreasing accuracy for increasing rates of unquantified observations. Increasing sample sizes lead to smaller bias. There is almost no change in the performance between two and four LLOQs. The magnitude of the variance impairs the performance of all methods. For a smaller variance, the multiple censored sample method leads to superior estimates regarding the RMSE and bias, whereas Helsel's method is superior regarding the bias for a larger variance. Under model misspecification, Helsel's method was inferior to the other methods. Estimating the mean, the multiple censored sample method performed better, whereas the multiple truncated sample method performs best in estimating the variance. Summarizing, for a large sample size and normally distributed data we recommend to use Helsel's method. Otherwise, the multiple censored sample method should be used to obtain estimates of the mean and variance of data including MLOQs.
Illustration of sexual differentiation to undergraduates with a conditional gene expression system
Authors: Shen Jie 
Published: September 2018

AbstractThis work describes the development and evaluation of a two‐session laboratory class based on Tet‐on technology and sex determination in the fruit fly Drosophila melanogaster. The Tet‐on system allows conditional control of gene expression, when doxycycline is applied. A laboratory exercise has been developed to illustrate how the Tet‐on technology conditionally over‐expresses the key sex determining gene transformer (tra) during development and how to inhibit sex differentiation in males, results in a lack of external genitalia and sex comb size reduction. The laboratory practice is inexpensive and straightforward, while allowing students to understand well how molecular biology technology can change biological processes, including development. © 2018 by International Union of Biochemistry and Molecular Biology, 46(5):523–526, 2018.
New vessels formation in young strokes with isolated steno‐occlusive MCA
Authors: Liang Meng , Wang Peng , Ma Yan , Zhang Xiaohao , Gao Jie , Ma Minmin , Dai Zhengze , Liu Dezhi , Liu Xinfeng 
Published: September 2018

AbstractObjectiveNew vessels formation (NVF) along the steno‐occlusive middle cerebral artery (MCA) is often observed in digital subtraction angiography (DSA) imaging. In the study, we aim to explore the clinical relevance of NVF in young ischemic stroke patients with isolated middle cerebral artery (MCA) stenosis.MethodsWe retrospectively reviewed the digital subtraction angiography (DSA) images of 93 young ischemic stroke patients (age ≤ 45 years old) in our center from January 2006 to June 2016. All the patients were diagnosed with isolated steno‐occlusive middle cerebral artery (MCA) disease.NVF was defined as new vessels formation along the stenotic MCA on anteroposterior DSA projection. The association between NVF and functional outcome was analyzed.ResultsThe prevalence of NVF was 0 in moderate stenosis, 15.8% in severe stenosis, and 53.7% in MCA occlusions. The presence of NVF had a strong correlation with the severity of MCA stenosis (r = 0.467, p < 0.001). Compared to patients without NVF, patients with NVF were more likely to suffer an unfavorable functional outcome (6.2% vs. 21.4%, p = 0.061) at 3 months. Univariate logistic regression analysis showed that NVF was associated with unfavorable outcome [Odds Ratio (OR) = 4.159, 95% confidence intervals (CI) = (1.072, 16.137), p = 0.039].ConclusionsThis study demonstrated that NVF were associated with poor clinical outcome in young ischemic stroke patients who were diagnosed with isolated steno‐occlusive MCA.
Socially responsible supplier selection and sustainable supply chain development: A combined approach of total interpretive structural modeling and fuzzy analytic network process
Authors: Chen Yuangao , Wang Shuo , Yao Jianrong , Li Yixiao , Yang Shuiqing 
Published: September 2018

AbstractSocially responsible supplier selection and sustainable supply chain development involve extremely important decision‐making processes in supply chain management encompassing many quantitative and qualitative factors to consider. Given the vagueness of experts' opinions and the complex interrelationships among evaluation criteria, this study proposes and illustrates a hybrid model that combines total interpretive structural modeling (TISM) and fuzzy analytic network process (FANP) to determine the most appropriate supplier from a social responsibility perspective. We use TISM to explain the interrelationships among variables and the FANP to calculate specific scores for each candidate. We illustrate an application of the proposed hybrid model using a case study from the Chinese food industry. The result demonstrates the feasibility and effectiveness of combining TISM and the FANP for socially responsible supplier selection. This research may provide managerial insights for practitioners to evaluate suppliers and develop sustainable supply chain strategies.
Low Energy Consumption of High‐Speed Centrifuges
Authors: Szepessy Stefan , Thorwid Peter 
Published: September 2018

AbstractA sharp reduction of the energy consumption of a high‐speed centrifuge was obtained following several design changes, while still maintaining separation capacity. This reduction is necessary for making some applications commercially interesting, e.g., large‐volume flow rates in the growing biopharma industry. The reduction was achieved by modifying flow paths of the rotor, i.e., reducing the outlet radius to minimize angular momentum losses and lowering the pressure drop of the internal flow. Further, removing air outside the rotor reduced aerodynamic losses, and using a direct drive motor, losses encountered with gear or belt drives were eliminated. This way, an average energy reduction of 50 % was obtained.
Development of Forecast Formulas for Assessing the Dust Formation Tendency of Moist Bulk Materials Using the UNC Dustiness Tester
Authors: Londershausen Tim , Schmidt Eberhard 
Published: September 2018

AbstractThe typically undesired release of particles from bulk materials can occur in a wide range of material‐handling processes and thus present a hazard to humans and the environment. Therefore, the dust formation tendency is an important material property and depends on the specific type of stress. A forecast of the dust formation tendency could simplify and expedite the assessment of possible hazard potentials as it would eliminate the need for comprehensive testing. For this paper, the UNC dustiness tester was applied to analyze the dust formation tendency of nine different materials. Based on the results obtained and taking account of the measurement method, it was possible to develop an apparatus‐specific forecast parameter, which allowed the derivation of empirical forecast formulas for the UNC dustiness tester.
The Energy Consumed by Electrochemical Molecular Machines as Self‐Sensor of the Reaction Conditions: Origin of Sensing Nervous Pulses and Asymmetry in Biological Functions
Authors: Otero Toribio F. , Beaumont Samuel 
Published: September 2018

AbstractFor reactions involving molecular machines (artificial or biochemical), the evolution of the reaction energy, or that of any of its components, adapts to and senses the working thermal, chemical, or mechanical conditions. Here, the state of the art and the attained sensing equations of the oxidation/reduction of conducting polymers seen as replicating materials and reactions of the intracellular matrix of functional cells (molecular machines, ions and water) are reviewed. The adapting reaction energy in actuating muscles and other organs can originate the nervous pulses translating its quantitative energetic information (thermal, fatigue state and mechanical) to the brain. Besides, reversible oxidation/reduction charges originate a great asymmetry of the consumed reaction energies, which could explain why evolution has selected and improved the most efficient of the two reactions to drive full asymmetric biological functions such as muscle contraction or the flow of nervous signals. The material reaction drives volume variations and energetic adaptation, two simultaneous functions that have allowed the development of artificial sensing‐muscles postulated to replicate some primitive artificial proprioception.
Applications of Pyrolytic Polyaniline for Renewable Energy Storage
Authors: Luo Yani , Guo Ruisong , Li Tingting , Liu Zhichao , Li Fuyun , Wang Baoyu , Zheng Mei , Yang Zhiwei , Wan Yizao , Luo Honglin 
Published: September 2018

AbstractA large number of studies have shown that nitrogen‐doped carbon can effectively improve the electrochemical performance of renewable energy storage devices. Polyaniline, as a carbon precursor rich in nitrogen heteroatoms, can be pyrolyzed to introduce a high content of structural nitrogen atoms into the carbon skeleton to fundamentally change the global properties of carbon materials including physical properties (e. g. surface polarity, electric conductivity, and wettability) and chemical properties (e. g. basicity and additional pseudocapacitance). Thus, nitrogen doping is extensively applied in the field of Li‐ion batteries, Li‐sulfur batteries, and supercapacitors to obtain excellent performance. Doping with different kinds of nitrogen configurations (e. g. pyridinic N, pyrrolic N, and graphitic N) shows respective mechanisms for the electrode materials of different energy storage devices. These mechanisms and applications of pyrolytic polyaniline in Li‐ion batteries, Li‐sulfur batteries, and supercapacitors are illustrated in detail here.
Binding Modes and Selectivity of Ruthenium Complexes to Human Telomeric DNA G‐Quadruplexes
Authors: Rubio‐Magnieto Jenifer , Kajouj Sofia , Di Meo Florent , Fossépré Mathieu , Trouillas Patrick , Norman Patrick , Linares Mathieu , Moucheron Cécile , Surin Mathieu 
Published: September 2018

AbstractMetal complexes constitute an important class of DNA binders. In particular, a few ruthenium polyazaaromatic complexes are attractive as “light switches” because of their strong luminescence enhancement upon DNA binding. In this paper, a comprehensive study on the binding modes of several mononuclear and binuclear ruthenium complexes to human telomeric sequences, made of repeats of the d(TTAGGG) fragment is reported. These DNA sequences form G‐quadruplexes (G4s) at the ends of chromosomes and constitute a relevant biomolecular target in cancer research. By combining spectroscopy experiments and molecular modelling simulations, several key properties are deciphered: the binding modes, the stabilization of G4 upon binding, and the selectivity of these complexes towards G4 versus double‐stranded DNA. These results are rationalized by assessing the possible deformation of G4 and the binding free energies of several binding modes via modelling approaches. Altogether, this comparative study provides fundamental insights into the molecular recognition properties and selectivity of Ru complexes towards this important class of DNA G4s.
Aerobic Aliphatic Hydroxylation Reactions by Copper Complexes: A Simple Clip‐and‐Cleave Concept
Authors: Becker Jonathan , Zhyhadlo Yevheniia Y. , Butova Ekaterina D. , Fokin Andrey A. , Schreiner Peter R. , Förster Moritz , Holthausen Max C. , Specht Pascal , Schindler Siegfried 
Published: September 2018

AbstractInvited for the cover of this issue are Siegfried Schindler, Peter R. Schreiner, Andrey A. Fokin, Max C. Holthausen, and co‐workers from Justus‐Liebig‐Universität Giessen, Igor Sikorsky Kiev Polytechnic Institute, and Johann Wolfgang Goethe‐Universität Frankfurt. The image depicts the clip‐and‐cleave concept for selective hydroxylation of aldehydes (adamantane 1‐carbaldehyde is shown as an example). Read the full text of the article at 10.1002/chem.201802607.
Interactions of C−F Bonds with Hydridoboranes: Reduction, Borylation and Friedel–Crafts Alkylation
Authors: Bamford Karlee L. , Chitnis Saurabh S. , Qu Zheng‐wang , Stephan Douglas W. 
Published: September 2018

AbstractThe stoichiometric reactions of the alkylfluorides 1‐fluoroadamantane (Ad‐F), fluorocyclohexane (Cy‐F), 1‐fluoropentane (Pent‐F) and benzyl fluorides with secondary boranes pinacolborane (HBpin), catecholborane (HBcat), 9‐borabicyclo(3.3.1)nonane (9‐BBN) and Piers’ borane (HB(C6F5)2) are described. While HBcat, 9‐BBN and HB(C6F5)2 reduce Ad‐F to Ad‐H, the latter borane was shown to react with secondary and primary fluoroalkanes, affording C−F borylation, while benzyl fluorides undergo Friedel–Crafts chemistry.
A new era of neoadjuvant treatment with Pertuzumab: Should the 10‐lymph node guideline for axillary lymph node dissection in breast cancer be revised?
Authors: O'Leary Michael P. , Beckord Brian J. , Mock Kyle E. , Venegas Rose J. , Yeh James J. , Dauphine Christine E. , Ozao‐Choy Junko J. 
Published: September 2018

AbstractBackgroundPertuzumab has improved pathologic complete response rates when compared with other chemotherapeutics in the treatment of HER‐2 positive breast cancer patients.AimsWe sought to determine if axillary lymph node dissections (ALNDs) yielding at least the national standard of 10 lymph nodes is lower in patients who received neoadjuvant pertuzumab.Methods and ResultsA retrospective database identified patients who underwent ALND for breast cancer. We compared the axillary lymph node retrieval rates in those who received or did not receive neoadjuvant pertuzumab. Of 139 breast cancer patients who underwent ALND, fewer than 10 axillary lymph nodes were found in 41.7% of patients who received neoadjuvant pertuzumab (P < 0.01) and 18.6% of patients who received neoadjuvant therapy without pertuzumab (P = 0.01).ConclusionNeoadjuvant chemotherapy was associated with a significantly lower rate of “adequate” ALNDs as defined by current guidelines. The patient subset that received neoadjuvant pertuzumab was more likely to have fewer than 10 axillary lymph nodes retrieved.
One‐round provably secure yoking‐proof for RFID applications
Authors: Sun Da‐Zhi , Zhu Ze‐Guang , Xu Guang‐Quan , Guo Wei 
Published: September 2018

SummaryThe yoking‐proof is the evidence that two or more RFID (Radio Frequency Identification) tags have been scanned simultaneously. Thanks to the IoT (Internet of Things), the yoking‐proof scheme becomes a very useful mechanism in many application areas such as health care and supply chain. However, the existing yoking‐proof schemes require two or more rounds of communication to generate the yoking‐proof. Following our idea presented in IEEE TrustCom 2017, we further investigate how to design the one‐round yoking‐proof scheme with efficiency advantage. Our contributions are threefold: (1) we propose a new timestamp‐based scheme for the RFID tag pair; (2) we prove the security and privacy of the proposed scheme under our models; (3) the proposed scheme is extended for the m > 2 RFID tags. In addition, the extended scheme still maintains one‐round of communication to generate the yoking‐proof.
Conformations and Binding Properties of Thiametoxam and Clothianidin Neonicotinoid Insecticides to Nicotinic Acetylcholine Receptors: The Contribution of σ‐Hole Interactions
Authors: Alamiddine Zakaria , Thany Steeve , Graton Jérôme , Le Questel Jean‐Yves 
Published: September 2018

AbstractThe structural features and molecular‐interaction properties of thiamethoxam (THA) and clothianidin (CLO) – two neonicotinoids – have been investigated through a combined approach based on a wide range of molecular modeling methods and X‐ray‐structure observations. Despite their close chemical structures, significant differences are emphasized by QM (DFT), docking, molecular dynamics, and QM/QM′ calculations. Thus, for the first time, their propensity to interact through chalcogen‐bond interactions is highlighted. The influence of the surroundings on this behavior is pointed out: in CLO, an intramolecular S⋅⋅⋅N chalcogen bond is shown to stabilize the structure in the solid state whereas the interaction leads to the preferred conformations in the isolated and continuum solvent models for both compounds. Interestingly, this interaction potential appears to be used for their binding toAc‐AChBP through intermolecular S⋅⋅⋅O chalcogen bonds with the hydroxyl group of Tyr195. The use of a suitable level of theory to describe properly these interactions is underlined, the classical methods being unsuited to highlight these interactions. The contribution of halogen bonding through the chlorine atom of the chlorothiazole ring in the binding of the two compounds is also underlined, both in the solid state and in theAc‐AChBP surroundings. However, the accommodation of the two insecticides in the binding site leads to the fact that a halogen‐bond contribution is pointed out only for CLO.