bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dari Keunggulan Menuju Kemenangan: Perjalanan Siswa Sekolah Indonesia Jeddah Menuju Kejayaan Olimpiade Sains Nasional
Authors: Malindo Anggraini Puspitasari  , Muhammad Thohir  , Mardiyah Mardiyah  
Published: December 2024

This research examines the management of the Indonesian School of Jeddah (SIJ) in supporting students towards the National Science Olympiad (OSN), with a focus on a student's academic journey. This research highlights student experiences, management strategies implemented by schools, as well as challenges faced during competition preparation. The role of school and family as main supporting factors is also analyzed. Students who have a strong interest in science are actively involved in extracurricular activities, such as science clubs and research projects, and develop time management skills to balance studies and other activities. The school provides a supportive learning environment, with resources and guidance from competent teachers. The family also makes a significant contribution through moral support and instilling a strong work ethic. This research uses a qualitative-descriptive approach with a case study method, which focuses on one research object to reveal the synergistic role between school and family in shaping student achievement. These findings illustrate the importance of collaboration between schools and families in creating student academic achievement.
Simulasi Sistem Keamanan Palang Pintu Kereta Api Menggunakan Mikrokontroler Arduino Uno
Authors: Naufal Cahyo Widodo  , Andi Purwanto  , Nadita Dwi Pramesti  , Paul Manurung  , Didik Aribowo  
Published: December 2024

The railway doorstop system functions to increase the safety of road users and avoid accidents at crossings. This journal discusses the design and implementation of a train doorstop system using Arduino Uno with supporting components such as servo motors, LED lights, resistors and the HC-SR04 ultrasonic sensor. The simulation aims to automate the process of closing and opening gate latches based on the presence of trains, with results demonstrating the effectiveness of the system in improving safety at crossings.
Evaluación de cáscaras de maracuyá y semillas de guayaba como bioadsorbentes para la remoción de Arsénico (III) en aguas superficiales
Authors: Pacari Romero Lizbeth , Mita Mamani Leidy Martha Mariela , Flores Choquemoroco Karina Estefania 
Published: December 2024

Este estudio investiga soluciones sostenibles para tratar aguas superficiales que son utilizadas como fuentes de consumo y abastecimiento con presencia de arsénico (III) con el objetivo de aprovechar las cáscaras de maracuyá y las semillas de guayaba modificadas como bioadsorbentes para la remoción de arsénico (As) en aguas superficiales de la provincia de Tacna, Perú. El estudio fue de tipo experimental, con un enfoque cuantitativo ya que se realizó la comparación de dos ensayos analizando su efectividad en la eliminación de As (III) en 500 ml de agua. Los resultados demostraron que las semillas de guayaba modificadas con Al₂(SO4)₃ tuvo mayor eficiencia en la remoción de As (III) con dosis de 3g, 7g y 10g siendo el mejor tratamiento con 3 gramos de adsorbente llegando a reducir de 0.152 ml/L a 0.128 ml/L de As (III). En comparación de la cáscara de maracuyá con dosis de 2g, 4g y 6g en donde la dosis de 6g fue la más efectiva, reduciendo la concentración de As de 0.0125 mg/L a 0.0112 mg/, en ambos casos influye el tamaño de partícula. En conclusión, la remoción de As (III) en aguas superficiales es viable.
RELAÇÃO ENTRE ATIVOS INTANGÍVEIS, PROPRIEDADE INTELECTUAL E REGISTRO CONTÁBIL
Authors: Fernandes Iverton José , Campos da Rocha Miranda Roberto , Souza Carmo Talita 
Published: December 2024

Este artigo apresenta a relação entre os termos ativos intangíveis e propriedade intelectual no contexto do registro contábil, identificando as formas como esses elementos se interagem na pesquisa acadêmica. Valendo-se de uma revisão sistemática que contempla a pesquisa dos termos em três idiomas – português, inglês e espanhol – no período de 10 anos (2013 a 2023) nas bases de dados, Google Acadêmico ® e Periódicos Capes (várias bases). Dos 144 registros levantados, 9 atenderam os critérios de seleção: interação entre os termos, relevância para estudos futuros, gaps na literatura sobre o assunto. Os resultados indicam que há espaço para aprimoramento de normas contábeis (com possível indicação e novos tipos de demonstrações) para registro de ativos intangíveis de propriedade intelectual, bem como necessidade de tratamento de especificidades diferenciadas entre setor privado e público.
PERFIL DE SENSIBILIDADE E RESISTÊNCIA ANTIMICROBIANA DE BACTÉRIAS ISOLADAS EM AMOSTRAS DE URINA NO MUNICÍPIO DE JI-PARANÁ, RONDÔNIA
Authors: Santos Joyce Kellen Iglesias Souto , Cândido Wesley Pimenta 
Published: December 2024

As infecções do trato urinário (ITU) representam um problema de saúde recorrente, especialmente em mulheres, devido a fatores anatômicos e fisiológicos. Nesta pesquisa, as amostras de urina coletadas no município de Ji-Paraná, Rondônia, foram categorizadas com base no gênero e espécie das bactérias, o perfil de sensibilidade aos antimicrobianos testados, o sexo e a idade dos participantes. Os dados foram organizados em gráficos para permitir uma análise detalhada da suscetibilidade por faixa etária e sexo. Objetivou-se avaliar o perfil de sensibilidade e resistência a antimicrobianos em bactérias isoladas, avaliar a relação entre suscetibilidade às infecções e faixa etária, e identificar as bactérias mais prevalentes em casos de ITU. Foi constatado que 81% dos quadros de ITU’s foram em mulheres, sendo a espécie Escherichia coli responsável por cerca de 52% dos casos em ambos os sexos.
Emerging Reporters in a Nascent Democracy: How Tunisian Pre-Professional Journalists Perceive and Use Social Media in Their Work
Authors: Nielsen Carolyn , Bowe Brian J. , Kooli Arwa 
Published: December 2024

Tunisia’s Jasmine Revolution facilitated the development of the nation’s first press freedoms. The success of the 2011 revolution is often attributed to social media, which played an influential role as a means of catalyzing resistance and communicating atrocities. However, social media was also used as a tool of disinformation. This study assessed how future journalists who had not worked in the field prior to the establishment of tentative press freedoms used social media in their reporting. This examination of Tunisian journalism students’ uses, values, and role perceptions regarding social media during a key period of post-revolution democracy building may serve as a barometer for the future of the field. Results demonstrate respondents primarily use social media to track breaking news, keep in touch with audiences, and find information. These uses most strongly correlate with the monitorial role, which is most closely associated with established democracies. Overall, respondents indicated the impacts of social media on their individual work were favorable.
The Effectiveness of the Use of Number Smart Board Learning Media to Improve Early Childhood Numeracy Skills
Authors: Makulua Korlina , Dahoklory Franklin Stevan , Lumaupuy Clinton 
Published: December 2024

Background. Learning in early childhood is an important foundation in the development of cognitive abilities, especially in numeracy skills. However, challenges in teaching the concept of counting effectively are often faced by educators. Interesting learning media, such as number smart boards, are expected to help overcome this obstacle. This media is designed to make it easier for children to understand the concept of numbers and basic operations of mathematics through fun and interactive methods.
Purpose. This study aims to test the effectiveness of the use of number smart board learning media in improving numeracy skills in early childhood. In addition, this study also focuses on how this media affects children's motivation to learn and whether there is a significant difference between the use of this media and conventional learning methods.
Method. This study uses a quantitative approach with an experimental design. The subjects of the study were children aged 4-6 years in a kindergarten who were divided into two groups, namely an experimental group that used the media of a number smart board and a control group that used traditional learning methods. Data collection was carried out through observations, numeracy tests, and questionnaires to measure children's motivation to learn.
Results. The results showed that children who learned to use a number smart board experienced a significant improvement in numeracy compared to the control group. In addition, the motivation to learn in the experimental group was also seen to be higher.
Conclusion. The use of number smart board learning media has been proven to be effective in improving early childhood numeracy skills. This media is also able to increase children's learning motivation, making it an effective alternative to conventional learning methods.
Usages académiques des TIC et qualité de vie des étudiant·e·s internationaux·les résident·e·s au Québec pendant le confinement COVID-19
Authors: Frozzini Jorge , Lévy Joseph , Côté Daniel , Bérubé Farrah 
Published: December 2024

Cet article rend compte des usages académiques des TIC ainsi que de leurs répercussions sur la qualité de vie des étudiant·e·s internationaux⋅les (EI) fréquentant des universités québécoises en période de confinement lié à la COVID-19. Les résultats de l’analyse de 40 entrevues semi-dirigées, dans cette recherche exploratoire qualitative, indiquent qu’il y a eu des répercussions significatives sur les finances des EI et les conditions d’enseignement et d’apprentissage. La démotivation, le manque de concentration, la fatigue ainsi que l’apparition ou l’amplification de problèmes physiques divers sont soulevés. Ces résultats illustrent l’importance de l’environnement technologique dans les études et la qualité de vie dans une situation de confinement.
El sector de los cuidados en la Economía Social asturiana. Un análisis desde la perspectiva de género
Authors: Santero-Sánchez Rosa , Martínez Martín Mª Isabel , Soria Lavara Pablo 
Published: December 2024

El envejecimiento es uno de los principales retos actuales y el sector de los cuidados es un sector emergente y estratégico, por su importante potencial de creación de empleo, asociado a la necesidad de dar respuesta a una demanda social que crecerá a un ritmo muy alto. El crecimiento previsto del sector debe acompañarse de un cambio del modelo, apoyado en servicios comunitarios, donde la economía social tiene una oportunidad de desarrollo.Tradicionalmente, los empleos del sector de los cuidados han supuesto una externalización del cuidado familiar y se han caracterizado por escaso valor social, alta precariedad y escasa proyección laboral, lo que hace que el sector sea poco atractivo. En Asturias, el sector cuenta con empresas muy feminizadas, donde las mujeres no solo se enfrentan a restricciones propias del sector, que han sido desplazadas al ámbito rural, sino también a las habituales brechas de género.El objetivo de este trabajo es analizar, con una visión global complementada con perspectiva de género, cuál es la posición de las empresas de economía social que prestan servicios vinculados a la economía de los cuidados en Asturias. Para ello, se utiliza una metodología mixta, cuantitativa, que caracteriza la participación de las empresas de Economía Social en el sector de los servicios en la región, y cualitativa, a través de entrevistas en profundidad y grupos de discusión, con asociaciones representantes de la demanda y oferta de cuidados, y personas expertas en servicios sociales e innovación social. Los resultados del análisis muestran que la economía social no sólo es decisiva en el nuevo modelo comunitario de cuidados, sino que, además, puede ser una vía para el emprendimiento y el empleo femenino a nivel local, pero se requieren actuaciones para que la participación de estas mujeres en el sector de los cuidados sea exitosa.
Screening of Solanaceous Plants for Resistance and Tolerance to Widespread Begomoviruses in Burkina Faso
Authors: OUATTARA Alassane , SOGOBA Kouka Hamidou , ZOMBRE Cyrille , BAYILI Sonia , KOÏTA Kadidia 
Published: December 2024

Solanaceous fruits are economically important and contribute to food security worldwide. Despite this importance, solanaceous crops are confronted with constraints, including begomoviruses. In Burkina Faso, the pepper yellow vein Mali virus (PepYVMLV) and the tomato leaf curl Mali virus (ToLCMLV) have been reported to be the most widespread begomoviruses. They are responsible for leaf deformation and yellowing in Solanaceae crops. The use of resistant/tolerant accessions would be of help in finding suitable solutions. This study aims to contribute to the appropriate and effective management of solanaceous diseases due to begomoviruses. To achieve this objective, an inventory of solanaceous accessions sold and produced in the western region of Burkina Faso and a screening of the preferred accessions were conducted in semi controlled conditions. Our results showed that twenty-seven accessions, including two newly introduced ones, were identified, with Mongal F1, Jaune du Burkina, and Simbad F1 being the most preferred. Preferred solanaceous plants were monitored for 39 days after whitefly-mediated transmission. The hot pepper Jaune du Burkina exhibited mild symptoms with an infection rate of 66%, while the tomato Mongal F1 and the sweet pepper Simbad F1 showed disease with severe symptoms with infection rates ranging from 33% to 100%. When the behaviors of newly introduced accessions were compared to most preferred accessions, the results indicated that the newly introduced accessions (Mona F1 and Ganga) showed mild symptoms, suggesting potential tolerance despite high infection rates. Howerever, it is suitable to access the impact of viruses on the productivity of these accessions.
Anbieterwechsel nach Art. 25 Data Act: Was geschieht mit der Vergütungspflicht? — Ein Überblick über den Ablauf des Anbieterwechsels und die währenddessen und danach bestehenden Vergütungspflichten
Authors: Nickel Moritz 
Published: December 2024

Zusammenfassung
Art. 25 Data Act (DA) schreibt vor, dass Anbieter von Datenverarbeitungsdiensten ab dem 12.9.2025 in ihren Musterverträgen Regelungen vorsehen müssen, die einen Wechsel zu einem anderen Anbieter ermöglichen. Hierzu stellt die Norm viele konkrete Anforderungen auf, die das Vertragswerk des Diensteanbieters einhalten muss. Für einen aus wirtschaftlicher Sicht entscheidenden Punkt macht Art. 25 DA aber keine in jeder Hinsicht klaren Vorgaben: Wie wirkt sich der Anbieterwechsel auf vereinbarte Vertragslaufzeiten und daraus resultierende Vergütungspflichten aus? Dieser Beitrag stellt zunächst den Ablauf des Anbieterwechsels dar und widmet sich dann der soeben aufgeworfenen Frage.
Die Abgabe von medizinischem Cannabis im System der gesetzlichen Krankenversicherung
Authors: Jacoby Saskia 
Published: December 2024

Zusammenfassung
Die medizinische Anwendung von Cannabis war bereits vor der Legalisierung im April 2024 umstritten aufgrund der geringen wissenschaftlichen Erkenntnisse und Einordnung als Betäubungsmittel. Die körperlichen und psychischen Auswirkungen werden jedoch erneut aufgrund der Aktualität des Themas diskutiert. Gegenstand dieses Beitrages ist die Einordnung von medizinischem Cannabis im System der GKV.
Online-Glücksspiele und Online-Sportwetten
Authors: Kaune Vincent 
Published: December 2024

Zusammenfassung
Bereits seit einigen Jahren befassen sich die deutschen Zivilgerichte wiederholt mit sog. „Spielerklagen“, mit denen die Nutzer von Online-Glücksspielen und Online-Sportwetten die Rückerstattung ihrer verlorenen Spieleinsätze gegenüber dem jeweiligiger Verfahren, die eine „Spielerklage“ zum Gegenstand haben, mit Blick auf zu erwartende Entscheidungen des EuGH in zwei Vorabentscheidungsverfahren angezeigt sein könnte. Der Beitrag geht dieser Frage auf Grundlage aktueller ober- und höchstrichterlicher Rechtsprechung nach und empfiehlt im Sinne einer möglichst einheitlichen Entscheidungspraxis, die derzeit bei den Gerichten anhängigen „Spielerklagen“ bis zu den Entscheidungen des EuGH auszusetzen.
The HSP90/Akt pathway may mediate artemether‐induced apoptosis of Cal27 cells
Authors: Wu Jianhua , Li Lei , Wang Yiting , Ren Xiaobin , Lin Ken , He Yongwen 
Published: August 2019

Tongue squamous cell carcinoma is the most common malignant tumor in oral and maxillofacial regions. Recent research has found that artemether can inhibit growth and induce apoptosis of cancer cells, although the mechanism is not clear. The present study aimed to explore the correlation between the HSP90/Akt pathway and artemether‐induced apoptosis of Cal27 cells. A cell counting kit‐8 and flow cytometry were used to detect the proliferation and apoptosis of Cal27 cells, respectively, mRNA expression was examined by quantitative RT‐PCR, and protein expression was detected by western blotting. Our data revealed that artemether can inhibit growth and induce apoptosis of Cal27 cells. As the artemether concentration was increased, we observed downregulation of the expression of HSP90, p‐Akt and p‐mTOR in Cal27 cells, whereas the expression of Akt was not significantly changed. We also observed a time‐dependent decrease in the expression of HSP90, p‐Akt and p‐mTOR during exposure to 0.1 mg·mL−1 artemether. In conclusion, the HSP90/Akt pathway may be involved in artemether‐induced apoptosis of Cal27 cells.
The clinical prognostic significance of ezrin in patients with bone and soft tissue sarcomas: a meta‐analysis
Authors: Wang Feng , Yu Tao , Ma Chengbin , Zhang Haifei , Zhang Zhiyu 
Published: August 2019

Ezrin is a member of the ezrin–radixin–moesin (ERM) protein family and has been shown to be associated with poor prognosis in patients with a variety of solid tumors. However, the clinical prognostic significance of ezrin in patients with bone and soft tissue sarcomas remains unclear. Here, we performed a systematic meta‐analysis by searching PubMed, the Cochrane Library Database, EMBASE, the Web of Science, and the CBM, WanFang Med Online and CNKI databases. In total, 19 studies with a total of 1316 bone and soft tissue sarcoma patients were included. Pooled analyses showed that ezrin overexpression was correlated with a higher rate of tumor metastasis (OR 6.59, 95% CI: 2.84–15.33, P < 0.01, PFDR < 0.01) and recurrence (OR 3.18, 95% CI: 1.88–5.37, P < 0.01, PFDR < 0.01) and a more advanced tumor grade (OR 3.252, 95% CI: 1.371–7.715, P = 0.01, PFDR = 0.03). Moreover, elevated ezrin expression could predict poor OS (HR 3.02, 95% CI: 2.35–3.89, P < 0.01, PFDR < 0.01), MFS (HR 5.22, 95% CI: 2.08–13.08, P < 0.01, PFDR < 0.01), and EFS (HR 1.07, 95% CI: 1.03–1.11, P < 0.01, PFDR < 0.01). Subgroup analyses revealed the underlying sources of heterogeneity. Publication bias was observed in the analysis of metastasis. Sensitivity analysis revealed that the results were robust. Our findings indicated that ezrin overexpression was significantly correlated with poor survival and more advanced tumor progression in bone and soft tissue sarcomas, which suggests that ezrin might be a valuable prognostic biomarker and a potential therapeutic target.
Binding Immunoglobulin Protein (BIP) Inhibits TNF‐α–Induced Osteoclast Differentiation and Systemic Bone Loss in an Erosive Arthritis Model
Authors: Zaiss Mario M. , Hall Christopher , McGowan Neil W. A. , Babb Rebecca , Devlia Vikesh , Lucas Sébastien , Meghji Sajeda , Henderson Brian , Bozec Aline , Schett Georg , David Jean‐Pierre , Panayi Gabriel S. , Grigoriadis Agamemnon E. , Corrigall Valerie M. 
Published: August 2019

ObjectiveThe association between inflammation and dysregulated bone remodeling is apparent in rheumatoid arthritis and is recapitulated in the human tumor necrosis factor transgenic (hTNFtg) mouse model. We investigated whether extracellular binding immunoglobulin protein (BiP) would protect the hTNFtg mouse from both inflammatory arthritis as well as extensive systemic bone loss and whether BiP had direct antiosteoclast properties in vitro.MethodshTNFtg mice received a single intraperitoneal administration of BiP at onset of arthritis. Clinical disease parameters were measured weekly. Bone analysis was performed by microcomputed tomography and histomorphometry. Mouse bone marrow macrophage and human peripheral blood monocyte precursors were used to study the direct effect of BiP on osteoclast differentiation and function in vitro. Monocyte and osteoclast signaling was analyzed by Western blotting, flow cytometry, and imaging flow cytometry.ResultsBiP‐treated mice showed reduced inflammation and cartilage destruction, and histomorphometric analysis revealed a decrease in osteoclast number with protection from systemic bone loss. Abrogation of osteoclast function was also observed in an ex vivo murine calvarial model. BiP inhibited differentiation of osteoclast precursors and prevented bone resorption by mature osteoclasts in vitro. BiP also induced downregulation of CD115/c‐Fms and Receptor Activator of NF‐κB (RANK) messenger RNA and protein, causing reduced phosphorylation of the p38 mitogen–activated protein kinases, extracellular signal–regulated kinases 1/2 and p38, with suppression of essential osteoclast transcription factors, c‐Fos and NFATc1. BiP directly inhibited TNF‐α– or Receptor Activator of NF–κB Ligand (RANKL)–induced NF‐κB nuclear translocation in THP‐1 monocytic cells and preosteoclasts by the canonical and noncanonical pathways.ConclusionBiP combines an anti‐inflammatory function with antiosteoclast activity, which establishes it as a potential novel therapeutic for inflammatory disorders associated with bone loss.
Catalytic Transfer Hydrodebenzylation with Low Palladium Loading
Authors: Yakukhnov Sergey A. , Ananikov Valentine P. 
Published: August 2019

AbstractA highly‐efficient catalytic system for hydrodebenzylation reaction is described. The cleavage of O‐benzyl and N‐benzyl protecting groups was performed using an uncommonly low palladium loading (0.02–0.3 mol%; TON up to 5000) in a relatively short reaction time. The approach was used for a variety of substrates including pharmaceutically important precursors, and gram‐scale deprotection reaction was shown. Transfer conditions together with easy‐to‐make Pd/C catalyst are the key features of this debenzylation scheme.magnified image
Palladium Nanoparticles‐Catalyzed Synthesis of Indanone Derivatives via Intramolecular Reductive Heck Reaction
Authors: Parveen Naziya , Sekar Govindasamy 
Published: August 2019

AbstractAn efficient protocol for the straightforward, single‐step synthesis of 3‐aryl‐1‐indanones from 2′‐iodochalcone via reductive Heck reaction using phosphine free, stable and reusable binaphthyl stabilized palladium nanoparticle (Pd‐BNP) as a catalyst has been described. An immense array of substrate scope with electron‐rich and deficient 2′‐iodochalcones have been synthesized. Further derivatization of product indanones have been achieved successfully. The heterogeneous nature of the Pd‐BNP has been validated by centrifugation test and mercury poisoning experiment. Pd‐BNP has been successfully recycled up to 5 cycles without any significant loss in reaction yield and particle size of nanoparticles, confirmed by TEM analysis.magnified image