bluuebunny/crossref_metadata_2025_split huggingface dataset:
The medium-term results of acromioclavicular joint arthroscopy with chondral and meniscal debridement
Authors: Bell Simon , Old Jason , Lewis Emma , Coghlan Jennifer 
Published: December 2018

Purpose: Surgical management of a young patient with a stable but painful acromioclavicular (AC) joint but normal imagining is a challenging problem. A standard arthroscopic excision of distal clavicle seems too aggressive. An alternative procedure is arthroscopic debridement of the joint, particularly the often torn meniscus, and chondroplasty. This study demonstrates in younger patients the medium-term result of arthroscopic debridement of a painful AC joint. Methods: Fifty-three young adult patients with a stable but painful AC joint, and virtually normal magnetic resonance imaging (MRI) scan, had arthroscopic debridement of the AC joint. Follow-up was with questionnaire and American Shoulder and Elbow Surgeons Shoulder Score (ASES). Results: Mean age was 29 years (18–39), 41 male, 31 dominant arm. Twenty-two patients demonstrated additional shoulder pathology. Two patients had a later distal clavicle excision. Five patients had later surgery to other areas of the shoulder but had an asymptomatic AC joint. Thirty-eight patients completed the ASES questionnaire at mean 44 months (24–86) post-operation. The mean ASES score was 82.8 (52–100). There was no association between ASES score and AC joint disease severity found at operation ( p = 0.25). Seven patients had ongoing shoulder symptoms, although none were severe enough to warrant any treatment. Conclusion: In this young group of patients with arthroscopic AC joint debridement, most had good relief of the AC joint related symptoms. This is a worthwhile procedure in the young patient, with quick recovery, and does not preclude further AC joint surgery later.
Depletion of murine fetal hematopoietic stem cells with c-Kit receptor and CD47 blockade improves neonatal engraftment
Authors: Witt Russell G. , Wang Bowen , Nguyen Quoc-Hung , Eikani Carlo , Mattis Aras N. , MacKenzie Tippi C. 
Published: December 2018

Key Points
Fetal injection of antibodies against the c-Kit receptor and CD47 effectively depletes host HSCs in immunocompetent mice. In utero depletion of host HSCs increases long-term engraftment after neonatal hematopoietic cell transplantation.
Towards the use of diffuse reflectance spectroscopy for real-time in vivo detection of breast cancer during surgery
Authors: de Boer Lisanne L. , Bydlon Torre M. , van Duijnhoven Frederieke , Vranken Peeters Marie-Jeanne T. F. D. , Loo Claudette E. , Winter-Warnars Gonneke A. O. , Sanders Joyce , Sterenborg Henricus J. C. M. , Hendriks Benno H. W. , Ruers Theo J. M. 
Published: December 2018

Abstract
Background
Breast cancer surgeons struggle with differentiating healthy tissue from cancer at the resection margin during surgery. We report on the feasibility of using diffuse reflectance spectroscopy (DRS) for real-time in vivo tissue characterization.

Methods
Evaluating feasibility of the technology requires a setting in which measurements, imaging and pathology have the best possible correlation. For this purpose an optical biopsy needle was used that had integrated optical fibers at the tip of the needle. This approach enabled the best possible correlation between optical measurement volume and tissue histology. With this optical biopsy needle we acquired real-time DRS data of normal tissue and tumor tissue in 27 patients that underwent an ultrasound guided breast biopsy procedure. Five additional patients were measured in continuous mode in which we obtained DRS measurements along the entire biopsy needle trajectory. We developed and compared three different support vector machine based classification models to classify the DRS measurements.

Results
With DRS malignant tissue could be discriminated from healthy tissue. The classification model that was based on eight selected wavelengths had the highest accuracy and Matthews Correlation Coefficient (MCC) of 0.93 and 0.87, respectively. In three patients that were measured in continuous mode and had malignant tissue in their biopsy specimen, a clear transition was seen in the classified DRS measurements going from healthy tissue to tumor tissue. This transition was not seen in the other two continuously measured patients that had benign tissue in their biopsy specimen.

Conclusions
It was concluded that DRS is feasible for integration in a surgical tool that could assist the breast surgeon in detecting positive resection margins during breast surgery.
Trail registration NIH US National Library of Medicine–clinicaltrails.gov, NCT01730365. Registered: 10/04/2012 https://clinicaltrials.gov/ct2/show/study/NCT01730365
Causal Associations in Type 2 Diabetes Development
Authors: Marott Sarah C W , Nordestgaard Børge G , Tybjærg-Hansen Anne , Benn Marianne 
Published: December 2018

Abstract

Context
Obesity, glucose, insulin resistance [homeostatic model assessment, version 2, for insulin resistance (HOMA2-IR)], and insulin secretion (HOMA2-β) have been associated with type 2 diabetes (T2D) observationally. However, the causal, genetic contribution of each parameter to this risk is largely unknown and important to study because observational data are prone to confounding but genetic, causal data are free of confounding and reverse causation.

Objective
We examined the causal, genetic contribution of body mass index (BMI), glucose level, C-peptide level, HOMA2-IR, and HOMA2-β to the risk of T2D in 95,540 individuals from the Copenhagen General Population Study and estimated the absolute 10-year risks.

Methods
Cox regression analysis, instrumental variable analysis, and Poisson regression analysis were performed to estimate the observational hazard ratios, causal, genetic ORs, and absolute 10-year risks of T2D.

Results
For 1-SD greater level, BMI was associated with an observational 66% (95% CI, 62% to 72%) and causal, genetic 121% (95% CI, 25% to 291%) greater risk of T2D; glucose with an observational 44% (95% CI, 41% to 46%) and causal, genetic 183% (95% CI, 56% to 416%) greater risk of T2D; and HOMA2-IR with an observational 30% (95% CI, 18% to 44%) and causal, genetic 12% (95% CI, 2% to 22%) greater risk of T2D. In contrast, for 1-SD greater level, HOMA2-β was associated with an observational 14% (95% CI, 11% to 16%) and causal, genetic 21% (95% CI, 8% to 32%) lower risk of T2D. The upper tertiles of HOMA2-IR were associated with absolute 10-year diabetes risks of 31% and 37% in obese women and men, age &gt;60 years, and a glucose level of 6.1 to 11.0 mmol/L.

Conclusions
BMI, glucose level, HOMA2-IR, and HOMA2-β are causally associated with T2D.
Concept of Excitation-Driven Boron Complexes and Their Applications for Functional Luminescent Materials
Authors: Gon Masayuki , Tanaka Kazuo , Chujo Yoshiki 
Published: December 2018

Abstract
It is commonly known that flexible structures and movable substituents are unfavorable for realizing intense luminescence with organic dyes. On the other hand, we show in this short review that excitation-driven boron complexes are promising platforms for obtaining stimuli-responsive luminescent materials with high sensitivity. Initially, we explained transformation of the valence of boron in heterofluorene from four to three-coordinate state through excitation-driven bond cleavage at the boron dative bond. The mechanism and stimuli-responsive luminescence with high sensitivity are illustrated. The next topic regards rational design of aggregation-induced emission (AIE)-active molecules, which are able to provide enhanced emission by aggregation. By employing theoretical calculations, it was possible to find a series of novel AIE-active skeletons from scratch. Stimuli-responsive luminescent chromism was also observed from the resulting molecules. The final topic is concerned with aryl–o-carborane dyads. It was recently found that rotation of the o-carborane unit proceeds triggered by photo-excitation. By regulating rotation behaviors, not only solid-state luminescence but also dual emission were obtained. The concept and several examples to offer applications of this new class of boron complexes are reviewed.
Factors influencing malignant mesothelioma survival: a retrospective review of the National Mesothelioma Virtual Bank cohort
Authors: Amin Waqas , Linkov Faina , Landsittel Douglas P. , Silverstein Jonathan C. , Becich Michael J. 
Published: December 2018

Background: Malignant mesothelioma (MM) is a rare but deadly malignancy with about 3,000 new cases being diagnosed each year in the US. Very few studies have been performed to analyze factors associated with mesothelioma survival, especially for peritoneal presentation. The overarching aim of this study is to examine survival of the cohort of patients with malignant mesothelioma enrolled in the National Mesothelioma Virtual Bank (NMVB). Methods: 888 cases of pleural and peritoneal mesothelioma cases were selected from the NMVB database, which houses over 1400 cases that were diagnosed from 1990 to 2017. Kaplan Meier’s method was performed for survival analysis. The association between prognostic factors and survival was estimated using Cox Hazard Regression method and using R software for analysis.Results:The median overall survival (OS) rate of all MM patients, including pleural and peritoneal mesothelioma cases is 15 months (14 months for pleural and 31 months for peritoneal). Significant prognostic factors associated with improved survival of malignant mesothelioma cases in this NMVB cohort were below the age of 45, female gender, epithelioid histological subtype, stage I, peritoneal occurrence, and had treatment that consisted of combining surgical therapy with chemotherapy. Combined surgical and chemotherapy treatment was associated with improved survival of 23 months in comparison to single line therapies.Conclusions:There has not been improvement in the overall survival for patients with malignant mesothelioma over many years with current available treatment options. Our findings show that combined surgical and chemotherapy treatment in peritoneal mesothelioma is associated with improved survival compared to local therapy alone.
Do age and mating status affect olfactory response of the parasitoid, Microplitis croceipes (Hymenoptera: Braconidae) to host-related plant odors?
Authors: Burrows Matthew , Morawo Tolulope , Fadamiro Henry 
Published: December 2018

Background: Parasitic wasps (parasitoids) use volatile organic compounds released by herbivore-infested plants to locate their hosts. Response of parasitoids to plant odors may be plastic and dependent on their physiological state. Using Microplitis croceipes (Hymenoptera: Braconidae), a relatively specialized larval endoparasitoid of Heliothis virescens (Lepidoptera: Noctuidae), we asked whether age and mating status of parasitoids affect their olfactory response to host-related odors. Methods: Four odor stimuli of varying complexity were selected based on previous reports of parasitoid response to cotton volatiles: cis-3-hexenol (a green leaf volatile), α-pinene (a constitutive monoterpene), a 50/50 v/v binary mixture (cis-3-hexenol + α-pinene), and H. virescens-infested cotton odors. Female M. croceipes used in Y-tube olfactometer bioassays were either mated or unmated, and grouped 1–3, 4–6, and 7–9 d-old. Female parasitoids used in electroantennogram (EAG) recording were mated and grouped 1–3, 4–6, 7–9 and 10–12 d-old. Results: In Y-tube olfactometer bioassays, neither age nor mating status played a major role in the attraction of parasitoids to test odor stimuli, with two exceptions: 4–6 d-old mated parasitoids showed attraction to the binary mixture, and 1–3 d-old mated parasitoids showed attraction to H. virescens-infested cotton. Age did not affect EAG response of parasitoids to test stimuli. Conclusions: The present results suggest that age and mating status do not play a major role in modulating olfactory responses of M. croceipes to host-related plant odors. Instead, plasticity of olfactory response may be limited in M. croceipes due to strong innate sensitivity to host-related odor cues.
SOLAR PV POWER PLANT LOCATION SELECTION USING A Z- FUZZY NUMBER BASED AHP
Authors: Kahraman Cengiz , Otay Irem 
Published: December 2018

One of the most used renewable energy systems to produce clean and sustainable energy are solar energy photovoltaic (PV) plants. The selection among solar energy PV plant location alternatives requires a multi-criteria decision making approach with several conflicting and linguistic criteria. The assessment process is generally done in a vague and imprecise environment. Fuzzy set theory is often very beneficial for evaluating the subjective judgments of decision makers. The Analytic Hierarchy Process is the most used multi-criteria decision making method in the world because of its simplicity and efficiency. In this paper, we select a location for a solar energy PV plant using a 4-level hierarchy. We consider several criteria and sub-criteria including initial cost, maintenance cost, slope and distance to highways. A Z-fuzzy number is a relatively new concept in fuzzy set theory that enables one to circumvent the limitations of ordinary fuzzy numbers. Z-fuzzy numbers can be viewed as a combination of crisp numbers, intervals, fuzzy numbers and random numbers because of their generality. They give a better representation than ordinary fuzzy numbers. This study solves the multi-criteria solar PV power plant location selection problem with a Z-fuzzy based AHP method. To check the applicability of the method proposed here, a real-life case study from Turkey is presented and solved.
Continuing to play: Music participation in the university years
Authors: Mantie Roger 
Published: December 2018

Abstract
The purpose of this study was to examine issues of continuity by asking non-music majors in a university marching band about their family involvement in music, formative music experiences, how their college music experiences compared to their prior involvements in music, their desires for improvement and their future plans for music involvement. Participants in the study (N = 12) were drawn from a large university in an urban setting in the southwestern United States. Findings suggest that most informants preferred their university over their high school experience; many informants reported being from smaller and/or lower achieving music programmes; strong family support was not a strong factor for recreational musical participation; and the informants had embodied the norms and expectations of marching band as a musical practice. Although a minority of informants appeared to have a clear conception of how they could continue to improve musically and continue to participate in music beyond graduation from university, most appeared less certain.
An ecological perspective on music programmes for at-risk children and families in Australia
Authors: Morell Laura , Shoemark Helen 
Published: December 2018

Abstract
The capacity for organizations to articulate key components of their programmes is pivotal in establishing and maintaining support from funding bodies and participating communities. This study sought to understand how music programme practitioners situate their programmes in the ‘music, health and well-being sector’. Practitioners and managers of two Australian music programmes for at risk children were interviewed about their understanding of the programmes for themselves, and how this understanding was communicated to participating communities and funding sources. The initial findings indicate that the two programmes operate within distinctly different theoretical frameworks – one based on a development and well-being theoretical framework, and the other in a sociological paradigm focused on the lived experience of music making. This distinction is important as it highlights the unique contributions of the two programmes to the wider ‘community music programmes’ sector.
Wing morphology in migratory North American monarchs: characterizing sources of variation and understanding changes through time
Authors: Freedman Micah G. , Dingle Hugh 
Published: December 2018

Abstract
Monarch butterfly wing morphology varies substantially throughout their global range, both between resident and migratory populations and also within the migratory North American population. Here, we use a dataset comprising more than 1800 North American individuals collected between 1878-2017 to characterize the factors shaping continent-wide patterns of wing morphological variation. North American overwintering butterflies have forewings that are approximately 4.4% larger than those collected in summer breeding areas. Monarchs overwintering in Mexico have forewings that are approximately 1.8% larger than monarchs overwintering in California, conducive to the idea that migration distance is positively correlated with wing area. We find evidence for a latitudinal cline within North America, such that butterflies collected at higher latitudes have significantly larger and more elongated forewings. We also find a significant increase of approximately 4.9% in forewing area between 1878-2017, but no difference through time in wing elongation. This result is corroborated by a reanalysis of a recently published dataset of more than 600 butterflies from Mexican overwintering sites. We discuss possible reasons for this increase in wing size through time, including northward shifts in the monarch’s breeding range and changes in relative abundance of milkweed hosts, and present experimental data addressing the influence of larval host plant on adult wing morphology. Our analysis suggests that (1) migration is indeed an important selective force for monarch wing morphology; (2) wing size has increased through time in North America; (3) factors such as host plant identity must be considered to fully understand monarch wing morphological variation.
Sequential Partial Migration Across Monarch Generations in Michigan
Authors: Malcolm Stephen B. , Vargas Natalia Ruiz , Rowe Logan , Stevens Joel , Armagost Joshua E. , Johnson Andrew C. 
Published: December 2018

Abstract
Running title: Monarch alternative migration: We collected 434 adult monarchs and surveyed milkweeds for immature monarchs in southwest Michigan, USA in order to test the hypothesis that monarchs are temporally variable, sequential partial migrants rather than partial migrants that may be spatially separated. Adult size, wing wear, female egg counts, fat content and sequestered chemical defenses were measured in monarchs across an entire season from spring migrant arrival, through breeding, until autumn migrant departure. We predicted that a population characterized by starting from all migrants and no residents, through breeding residents, to all migrants and no residents should show life history measures consistent with changes in these proportions. Results show that female monarch spring migrants arrive with chorionated eggs and high wing loads in both intact and fat-extracted adults. Wing loads of both males and females decrease during the summer and increase again immediately before autumn departure, when the fat content of all adults increases markedly. The high fat content of spring arrivals is also characteristic of migrants. Cardenolide content of adults showed a similar pattern of high content in spring arrivals, a decrease in the summer and then an accumulation of cardenolide defenses in adults in late summer just before migratory departure. We conclude that these results are consistent with temporally variable, sequential partial migration in a short-lived insect that contrasts with spatially variable partial migration in longer-lived vertebrates.
The similarity of selected statins – a comparative analysis
Authors: Dreyer Constantin , Placha Wojciech , Zagajewski Jacek , Dygut Jacek , Stangel-Wójcikiewicz Klaudia , Piwowar Monika 
Published: December 2018

Abstract
The paper presents the physicochemical and structural characteristics as well as the comparison of selected statins. Statins are relatively popular compounds used in modern medicine. They are increasingly often combined with other medications to improve the effectiveness of therapy. We analyzed the characteristics of pravastatin, simvastatin, atorvastatin, pitavastatin, lovastatin, mevastatin, fluvastatin, and rosuvastatin obtained from the PubChem Substance database. On the basis of data related to chemical structure and physicochemical properties, the statins were grouped into more and less similar ones. Statins are not homogeneous in terms of physicochemical properties and structure. Three groups of statins were identified. Mevastatin, lovastatin, and simvastatin are the most similar to each other, while pravastatin shows a slightly lower similarity to them. Pitavastatin and fluvastatin are also highly similar, while atorvastatin and rosuvastatin, because of their properties, are the most different from other statin groups.
“A Wide-Angle View of Fragile Earth”: Capitalist Aesthetics in The Work of Yann Arthus-Bertrand
Authors: Druick Zoë 
Published: December 2018

Abstract
Taking the widely viewed media work of French filmmaker and environmentalist Yann Arthus- Bertrand’s as its subject, this essay posits that despite the filmmaker’s stated ecological and humanist position, the formalist strategies he employs-particularly the fly-over and the database-bring with them a set of historical conventions that paradoxically import capitalist and imperialist ideologies and phenomenologies. In particular, the article considers the films Home (2009) and Human (2015) and the database project 7 Billion Others (2003-ongoing) as documentaries that deploy techniques of technologically-virtuosic seeing that end up obscuring the very possibility of cognitive mapping that would allow viewers to situate their contents in legible political economic frameworks. Closely related to the concept of the Anthropocene, which holds all people equally accountable for the current environmental crisis, Arthus- Bertrand’s work tends to obscure the causes and therefore meaningful solutions for the current situation. The article concludes by postulating that the model of cognitive mapping itself requires more attention to the ways in which particular aesthetic forms mobilize affective dimensions of viewer experience.
The Temporal Resistance of Kelly Reichardt’s Cinema
Authors: Henry Claire 
Published: December 2018

Abstract
Across her six feature films since 1994, American director Kelly Reichardt has taken time as a mechanism to reveal and question social, political, and economic structures. This article looks closely at how her films display a range of temporal interventions and resistances to features of capitalist temporalities. While film theorists and critics often locate Reichardt’s films within “slow cinema,” this article expands the range of temporal concepts applied to her films to explore the sociopolitical critique at work through this auteur’s aesthetics. The analysis focuses on time in three of Reichardt’s feature films, starting with commodified and metaphysical time in Old Joy (2006), then addressing impatience, entropy, and environmentalism’s temporalities in Night Moves (2013), and ending with an exploration of disconnection-and denial of coevalness-in Certain Women (2016). This article applies close scene analysis-along with a range of philosophical, political, and sociological concepts of time-to demonstrate how Reichardt elucidates and resists the temporal tensions underpinning social relations within capitalist culture.