bluuebunny/crossref_metadata_2025_split huggingface dataset:
EXCELÊNCIA NA PRESTAÇÃO DE SERVIÇOS: APLICAÇÕES DE ESTUDO DE LAYOUT, JANELA DO CLIENTE E DIAGRAMA DE ISHIKAWA
Authors: Piñol Susana , Kowalski Camile , Fonseca Giovana , Souza Neto Edinor de , Rosa Marceli Jacintho , Santos Natália dos 
Published: October 2019

Organizações que tenham como objetivo oferecer serviços de excelência aos seus clientes necessitam contar com gestores que entendem o comportamento de compra de seu público e que apliquem sistematicamente ferramentas de gestão de qualidade.O cliente, para adquirir seu bem ou seu produto, passa por diversas etapas, ou seja, um processo até finalmente chegar a sua decisão final de compra. Segundo Kotler (2002), existem “tipos de decisões” na hora de realizar a compra, que podem serclassificados da seguinte forma: o comportamento de compra rotineiro, onde o comportamento é do tipo mais simples, já que nesse caso, a procura para realização do processo é mais frequente, logo, o comprador estará familiarizado com os preços e com o serviço prestado. O segundo é a solução de problemas limitados. O comprador já teve contato com o serviço, mas não com aqueles que prestam os serviços que estão disponíveis. E por último, a procura da solução para problemas maiores, nos casos onde o comprador nunca teve contato com o serviço determinado antes.Ainda nesse processo de decisão, de acordo com Kotler et al.(2002), há aqueles que participam na hora de dar a resposta final sobre a compra, que auxiliam nonmomento de decisão. Estes são: O iniciador, que é aquela pessoa que indica, aponta tal serviço. Já o influenciador e o decisor possuem papéis parecidos, já que ambas as opiniões são levadas em conta, sendo o decisor aquele que, no último instante, influencia o veredicto do cliente. O comprador e o usuário, são respectivamente, aquele que concretiza a compra e aquele que utilizará o serviço prestado.Este artigo apresenta como objetivo geral descrever a aplicação de três ferramentas de gestão da qualidade: Estudo de Layout, Janela do Cliente e Diagrama de Ishikawa junto a um salão de beleza. Estas ferramentas foram aprendidas em sala deaula pelos alunos do Curso de Administração Integrado ao Ensino Médio do Instituto Federal Catarinense de São Francisco do Sul e, posteriormente, aplicadas em uma pequena empresa que abriu suas portas para este projeto extensionista. Como objetivos específicos buscou-se obter o consentimento da empresa para realização do projeto, verificar o comportamento do consumidor desta organização, aplicar o Estudo de Layout no espaço de circulação dos clientes, aplicar a ferramenta de Janela do Cliente junto aos clientes, aplicar o Diagrama de Ishikawa considerando um efeito indesejado pelos gestores, propor algumas melhorias com vistas à excelência na prestação deserviços da empresa.
Comparison of accuracy and stability between disposable arterial blood syringes and pre-heparinized syringe in arterial blood gas analysis: a retrospective study
Authors: Zhao Xiexiong , Swai Joel Dominic , Chen Huiling , Tang Huiting , Wang Junwen , Li Jiaying , You Nana , Wu Yuyan , Zhou Xiaoyu , Jiang Weihong , Li Xiaogang 
Published: October 2019

Abstract
Background

Arterial blood gas (ABG) analysis is vital in the emergency department. However, the accuracy and stability of some indicators in ABG analysis are debatable compared with venous ones. Disposable arterial blood syringe (DABS) usage is increasing in clinical practice. To compare the accuracy and stability of venous versus arterial blood results and newly emerging DABS versus traditionally used pre-heparinized syringe (PHS) results, we performed this study.Methods

This retrospective study was performed at the emergency department of the Third Xiangya Hospital of Central South University. Participants were divided into two groups PHS and DABS, from which venous and arterial blood was drawn and analyzed either in laboratory or ABG-analyzer. Blood sample results were compared by the Pearson correlation coefficient and t-test. By removing extreme results, the sensitivity analysis was conducted.Results

A total of 500 patients (64.80% male, mean age 63.55±16.82) and 400 patients (65.25% male, mean age 62.86±15.65) were enrolled in PHS and DABS groups, respectively. Compared with PHS group, DABS had a quite higher correlation coefficient in K + (0.923 vs. 0.855), Na + (0.911 vs. 0.850) and the differences between venous and arterial of all indicators (K + 0.202mmol/L vs. 0.318mmol/L, P<0.0001; Na + 1.187mmol/L vs. 2.902mmol/L, P<0.0001; Cl - -5.336mmol/L vs. –7.598mmol/L, P<0.0001; Hb -0.898g/L vs. 2.212g/L, P<0.0001; HCT -0.659% vs. 1.269%, P<0.0001) were significantly smaller in DABS group.Conclusion

High accuracy was seen in arterial blood results irrespective of the usage of PHS or DABS for sample collection. DABS showed more accurate and stable results, suggesting its role for future medical use.
Use of the rSpaA415 antigen indicates low rates of Erysipelothrix rhusiopathiae infection in farmed cattle from the United States of America and Great Britain
Authors: Atienzar Ana Isabel Cubas , Gerber Priscilla F. , Opriessnig Tanja 
Published: October 2019

Abstract
Background
Clinical cases of Erysipelothrix rhusiopathiae, a zoonotic gram-positive bacterium, have been reported in many ruminant species, including in cattle, deer, moose and muskoxen. Fatal cases have been repeatedly reported in cattle over the years but to date there is only one Japanese study investigating the seroprevalence of this bacterium in cattle using the growth agglutination test (GAT). This technique is subjective, time-consuming, expensive and hazardous compared to modern serological tests such as enzyme-linked immunosorbent assays (ELISA) or the newly developed fluorescent microbead-based immunoassays (FMIA).
Results
A FMIA based on the surface protein SpaA (rSpaA415) antigen of E. rhusiopathiae developed in this study had an almost perfect agreement with the GAT (k=0.83) and showed a sensitivity of 89.7% and a specificity of 92.9% when compared to the GAT. Overall, detection rates of E. rhusiopathiae antibody positive samples were 13.8% (51/370) in British herds and 6% (12/200) in US herds. Positive cattle were present in 34.3% (24/70) of the investigated British farms and in 34.7% (8/23) of the US farms with an on-farm prevalence of 7.1% to 100% for the British and 8.3-30% for the US.
Conclusions
FMIA is a fast, safe and economic alternative to the GAT for the diagnosis of E. rhusiopathiae in cattle. This work is the first seroprevalence study of E. rhusiopathiae in healthy farmed cattle in the Great Britain and the US and revealed that infection occurs at a low level. Further investigations to evaluate risks of zoonotic transmission when handling cattle are needed.
Longitudinal analysis of historical payments and utilization in patients with hip and knee osteoarthritis
Authors: Allen Jackson , Moore Meredith Grogan , Marushack Luke M , O'Donnell Jonathan , Jiranek William , Mather Richard Charles , Bozic Kevin J 
Published: October 2019

Abstract
Background Osteoarthritis (OA) is a highly prevalent condition associated with substantial clinical and economic burden. Value-based payment reform requires detailed understanding of care utilization. However, previous analyses of OA care have limitations, such as constraining analysis to a single year or to surgical patients. We aimed to more comprehensively characterize health services utilization and payment for hip and knee OA through a 3-year longitudinal analysis, including both operative and non-operative services, using Medicare claims data. Methods We utilized Medicare Standard Analytic Files available from PearlDiver, Inc. The target population for analysis was patients with osteoarthritis in the hip, knee, or both, identified by ICD-9 diagnosis codes. Patients were limited to those whose 1) first instance of hip or knee OA diagnosis in the payer dataset occurred between 2008 and 2011 and 2) who were continuously active in the payer dataset for one year prior to and three years following diagnosis. Results Payments for relevant hip and knee OA services were highest during the first year after diagnosis, representing 55.6%, 65.3%, and 51.2% of total payments for patients with knee, hip, or knee and hip OA, respectively. Payments and utilization of services in the second and third treatment years were lower, and similar to the year prior to OA diagnosis. Service-level analysis revealed that total payments were driven by utilization of high-intensity services like surgery, which accounted for 57.7%, 60.6%, and 63.6% of payments in the first year for knee, hip, and knee and hip OA patients, respectively. High utilization of Medical Services like physician-administered medications, arthrocentesis, and physical therapy drove high payments as well, especially later in treatment. Conclusion Hip and knee OA treatment intensity is highest in the year immediately following a new diagnosis and decreases considerably in the second- and third-years following diagnosis across all relevant service categories. This analysis supports the identification of specific, time-sensitive opportunities to transform hip and knee OA care and payment models to optimize patient-centered outcomes while controlling costs across the episode of care.
Helicobacter pylori: A Cause of Community-Acquired Pediatric Septic Shock: A Cross Sectional Study
Authors: Algebaly HebatAllah , Elsherif Rasha , Ghaith Doaa , Saad Bassem , Mohsen Nabil 
Published: October 2019

Abstract
Background: Blood culture negative sepsis is a diagnostic challenge to both clinicians and microbiologists. We aimed to investigate blood culture negative cases of community-acquired sepsis among children admitted at pediatric intensive care unit of Cairo University Specialized Children Hospital, Egypt. Methodology: Our cross-sectional study was carried out over a period of six months. Electrical cardiometry was used to assess the patients’ status. For blood culture negative samples, broad range bacterial and fungal PCR amplification and sequencing were performed. Results: Among 43 patients, 9 samples were positive to pan bacterial 16srRNA gene, while five samples (20,22,23,24,25) were identified as Helicobacter pylori positive with the following sequence accession numbers respectively (KT198991.1, JQ323580.1, APEL01000010.1, APEL01000010.1, CP007603.1). Patients H pylori positive higher C reactive protein, longer duration of ventilation, higher stroke volume variation and pre-ejection period (P value= 0.005, 0.005, 0.043 & 0.043) Conclusion: Detection of Helicobacter pylori in community acquired septic children alarms the necessity to conduct epidemiological studies on populations of septic shock in countries with high prevalence of H. pylori such as Egypt.
The viability of co-active fuzzy inference system model for monthly reference evapotranspiration estimation: case study of Uttarakhand State
Authors: Malik Anurag , Kumar Anil , Ghorbani Mohammad Ali , Kashani Mahsa H. , Kisi Ozgur , Kim Sungwon 
Published: October 2019

Abstract
Reference evapotranspiration (ETo) is a major component of the hydrological cycle linking the irrigation water requirement and planning and management of water resources. In this research, the potential of co-active neuro-fuzzy inference system (CANFIS) was investigated against the multilayer perceptron neural network (MLPNN), radial basis neural network (RBNN), self-organizing map neural network (SOMNN) and multiple linear regression (MLR) to estimate the monthly ETo at Pantnagar and Ranichauri stations, located in the foothills of Indian central Himalayas of Uttarakhand State, India. The significant combination of input variables for implemented techniques was decided by the Gamma test (GT). The results obtained by CANFIS models were compared with MLPNN, RBNN, SOMNN and MLR models based on performance evaluation indicators and visual inspection using line, scatter and Taylor plots for both the stations. The results of comparison revealed that CANFIS-5/CANFIS-9 models (RMSE = 0.0978/0.1394, SI = 0.0261/0.0475, COE = 0.9963/0.9846, PCC = 0.9982/0.9942 and WI = 0.9991/0.9959) with three and five input variables provide superior results for estimating monthly ETo at Pantnagar and Ranichauri stations, respectively. Also, the adopted modelling strategy can build a truthful expert intelligent system for estimating the monthly ETo at the study stations.
Effect of nitrite and nitrate on sulfate reducing ammonium oxidation
Authors: Zhang Dandan , Cui Li , Madani Rayan M. A. , Wang Hui , Zhu Hao , Liang Jiyan 
Published: October 2019

Abstract
The effects of nitrite and nitrate on the integration of ammonium oxidization and sulfate reduction were investigated in a self-designed reactor with an effective volume of 5 L. An experimental study indicated that the ammonium oxidization and sulfate reduction efficiencies were increased in the presence of nitrite and nitrate. Studies showed that a decreasing proportion of N/S in the presence of NO2− at 30 mg·L−1 would lead to high removal efficiencies of NH4+-N and SO42–-S of up to 78.13% and 46.72%, respectively. On the other hand, NO3− was produced at approximately 26.89 mg·L−1. Proteobacteria, Chloroflexi, Bacteroidetes, Chlorobi, Acidobacteria, Planctomycetes and Nitrospirae were detected in the anaerobic cycle growth reactor. Proteobacteria was identified as the dominant functional bacteria removing nitrogen in the reactor. The nitritation reaction could promote the sulfate-reducing ammonium oxidation (SRAO) process. NH4+ was converted to NO2 and other intermediates, for which the electron acceptor was SO42−. These results showed that nitrogen was converted by the nitrification process, the denitrification process, and the traditional anammox process simultaneously with the SRAO process. The sulfur-based autotrophic denitration and denitrification in the reactor were caused by the influent nitrite and nitrate.
Professional Education in The Post – Industrial Economy : Challenges of Digital Transformation
Authors: Sadovaya E. S. 
Published: October 2019

The article analyses the development trends of professional education in the context of global shifts taking place in the modern economy due to its technological development. The transfer of business processes to the digital environment leads to a radical reformatting of the entire sphere of labor, a change in its quality, as well as forms of interaction between people in the production of goods and services. The author identifies the main factors that have a decisive influence on the evolution of the professional activity of the person, radically changing the requirements for the professional education system, both in terms of its content, and methods of getting it. The main factors of the ongoing transformations, according to the author, include the rapid spread of digital platforms, replacing the traditional sectors of the economy, and the automation of cognitive activity based on the algorithmic repetition of a certain set of actions. Analyzing the effect of these factors, the author notes their contradictory effect on the sphere of professional employment and vocational education, comes to the conclusion that it is necessary to radically change the very paradigm of the development of vocational education, implement non-trivial organizational decisions in the process of transforming its institutional infrastructure. The article emphasizes that professional education in modern conditions is becoming not just a connecting link between the labor market and a person, but it is the beginning to fulfill a wide range of social functions. This is especially important in the context of a reduction in the scope of labor in the high-tech digital economy.
Corporate Tax Reform in the USA
Authors: Bogaevskaya O. V. 
Published: October 2019

The article examines the prerequisites, content and effects of changes in the corporate taxation system adopted in the United States under the Tax Cuts and Jobs Act in December 2017. The critical flaws and limitations of the US corporate taxation system that existed until 2018 are analyzed in detail. A conceptual consensus on the need to reduce the corporate tax rate and solving the problem of profit shifting existed in the US expert community for some time before the election of President D. Trump, but the balance of power in Congress made the changes impossible. The key provisions of the new corporate tax system, which primarily include a reduction in the corporate tax rate, reforming companies’ international taxation and measures to stimulate investment in the United States, are outlined. The expected consequences and first results of the reform, the impact of the adopted changes on the activities of different types of companies and on the US economy are considered. It is shown that the reform will lead to increased activity of both American and foreign companies on the US territory, as well as, possibly, a decrease in corporate tax rates in other countries. It is concluded that, despite the considerable budget burden, the tax reform will contribute to economic growth in the United States, both in the short and long run.
Quem escreve arquiva a própria vida na memória social
Authors: Laffin Marcos 
Published: October 2019

Este ensaio literário coloca em movimento um entendimento de memória e escrita como instrumental de desenvolvimento humano. Apresenta excertos da poesia de duas escritoras como representação de memórias da cidade de Joinville. Ao sugerir o não esquecimento como polaridade da memória, reivindica um cotidiano menos apressado e menos imediato. Utiliza-se o ensaio literário por sua condição de provisoriedade, pela transição mutante da polissemia das palavras. Nessa forma, articula linguagem poética e racionalidade, em que procura evidenciar o rigor sem desejar a exatidão, contudo carrega e deixa as marcas subjetivas de quem afirma a autoria. O ensaio eleva-se na e para a estética e a polidez ao articular o contínuo e o descontínuo da unidade e ruptura, pois em sua finalidade irrompem certas afirmações escolhidas na busca de sua contrapalavra. Na primeira parte, “Do átomo à escrita: em síntese!”, fala-se da rudimentar memória como própria do humano, e, sendo biológica, é apenas incipiente no porvir do desenvolvimento que reclama o contexto sócio-histórico para a não alienação. Na sequência, convoca “a cidade e suas palavras”, para evidenciar a escrita no contexto que reivindica a memória e o não esquecimento. A complexidade e o apressado cotidiano tendem ao imediatismo, à vida sem história e ao esquecimento. Por último, no léxico dos saberes humanos, “quem escreve arquiva a própria vida na memória social” sugere um arregimentar de inventários de interlocuções para combater o esquecimento.
Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning
Authors: Kabir Md. Tanvir , Uddin Md. Sahab , Begum Mst. Marium , Thangapandiyan Shanmugam , Rahman Md. Sohanur , Aleya Lotfi , Mathew Bijo , Ahmed Muniruddin , Barreto George E. , Ashraf Ghulam Md. 
Published: October 2019

:In the brain, acetylcholine (ACh) is regarded as one of the major neurotransmitters. During the advancement of Alzheimer's disease (AD) cholinergic deficits occur and this can lead to extensive cognitive dysfunction and decline. Acetylcholinesterase (AChE) remains a highly feasible target for the symptomatic improvement of AD. Acetylcholinesterase (AChE) remains a highly viable target for the symptomatic improvement in AD because cholinergic deficit is a consistent and early finding in AD. The treatment approach of inhibiting peripheral AChE for myasthenia gravis had effectively proven that AChE inhibition was a reachable therapeutic target. Subsequently tacrine, donepezil, rivastigmine, and galantamine were developed and approved for the symptomatic treatment of AD. Since then, multiple cholinesterase inhibitors (ChEIs) have been continued to be developed. These include newer ChEIs, naturally derived ChEIs, hybrids, and synthetic analogues. In this paper, we summarize the different types of ChEIs which are under development and their respective mechanisms of actions.
Current Disposal Practices of Unused and Expired Medicines Among General Public in Delhi and National Capital Region, India
Authors: Manocha Sachin , Suranagi Umesh D. , Sah Ravinder K. , Chandane Rakhamaji D. , Kulhare Sumit , Goyal Nitesh , Tanwar Krishna 
Published: October 2019

Background:
Stocking unused or expired medicines or donating these to others can lead
to accidental or inappropriate ingestion, increasing the risk of adverse drug reaction(s) and even
lead to antibiotic resistance. Further improper disposal of expired or unused medicines is associated
with environmental pollution, health hazards and damage to ecosystem. Ecopharmacovigilance is an
important area in this context.

Objective:
To explore the awareness and disposal practices of unused/expired in the general public.

Material and Methods:
The current study is an observational, cross-sectional, questionnaire-based study
conducted in 956 medicine consumers in New Delhi and National Capital Region, India. The knowledge,
attitude, and practice of consumers regarding the disposal of unused medicines were evaluated.

Results:
The majority (89.9%) of consumers opined that expiry of medicine(s) meant for completion
of shelf life, production of toxic chemical and loss of or decreasing of beneficial effects of
medicines. Majority (87%) of the consumers stored medicines at home. Almost all (92.6%) of the
consumers threw away the expired medicines after storing for few days. Consumers discarded the
expired medicines mainly in household trash (73%). The majority (93%) of consumers were in favour
of a government program to collect unused or expired medicines from their home.

Conclusion:
The knowledge and practices of consumers towards disposal of unused and expired
medicines needs to be improved. Health care professionals, government and policy makers should
offer training to educate and guide the general public on safe and proper disposal practices of expired
or unused medicines.