bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Evaluation of Army Wellness Center Clients’ Health-Related Outcomes
Authors: Rivera L. Omar , Ford Jessica Danielle , Hartzell Meredith Marie , Hoover Todd Allan 
Published: February 2018

Purpose: To examine whether Army community members participating in a best-practice based workplace health promotion program (WHPP) experience goal-moderated improvements in health-related outcomes. Design: Pretest/posttest outcome evaluation examining an autonomously participating client cohort over 1 year. Setting: Army Wellness Center facilities on 19 Army installations. Participants: Army community members sample (N = 5703), mostly Active Duty Soldiers (64%). Intervention: Assessment of health risks with feedback, health assessments, health education classes, and health coaching sessions conducted by health educators at a recommended frequency of once a month for 3 to 12 months. Measures: Initial and follow-up outcome assessments of body mass index (BMI), body fat, cardiorespiratory fitness, blood pressure, and perceived stress. Analysis: Mixed model linear regression testing for goal-moderated improvements in outcomes. Results: Clients experienced significant improvements in body fat (−2% change), perceived stress (−6% to −12% change), cardiorespiratory fitness (+6% change), and blood pressure (−1% change) regardless of health-related goal. Only clients with a weight loss goal experienced BMI improvement (−1% change). Follow-up outcome assessment rates ranged from 44% (N = 2509) for BMI to 6% (N = 342) for perceived stress. Conclusion: Army Wellness Center clients with at least 1 follow-up outcome assessment experienced improvements in military readiness correlates and chronic disease risk factors. Evaluation design and follow-up-related limitations notwithstanding results suggest that best practices in WHPPs can effectively serve a globally distributed military force.
Featured Article: Immunomodulatory effect of hemozoin on pneumocyte apoptosis viaCARD9pathway, a possibly retarding pulmonary resolution
Authors: Maknitikul Sitang , Luplertlop Natthanej , Chaisri Urai , Maneerat Yaowapa , Ampawong Sumate 
Published: February 2018

Plasmodium falciparum, the most virulent malaria parasite species, causes severe symptoms especially acute lung injury (ALI), of which characterized by alveolar epithelium and endothelium destruction and accelerated to blood–gas-barrier breakdown. Parasitized erythrocytes, endothelial cells, monocytes, and cytokines are all involved in this mechanism, but hemozoin (HZ), the parasitic waste from heme detoxification, also mainly contributes. In addition, it is not clear why type II pneumocyte proliferation, alveolar restorative stage, is rare in malaria-associated ALI. To address this, in vitro culture of A549 cells with Plasmodium HZ or with interleukin (IL)-1β triggered by HZ and monocytes (HZ-IL-1β) was conducted to determine their alveolar apoptotic effect using ethidium bromide/acridine orange staining, annexin-V-FITC/propidium iodide staining, and electron mircroscopic study. Caspase recruitment domain-containing protein 9 ( CARD9), the apoptotic regulator gene, and IL-1β were quantified by reverse-transcriptase PCR. Junctional cellular defects were characterized by immunohistochemical staining of E-cadherin. The results revealed that cellular apoptosis and CARD9 expression levels were extremely high 24 h after induction by HZ-IL-1β when compared to the HZ- and non-treated groups. E-cadherin was markedly down-regulated by HZ-IL-1β and HZ treatments. CARD9 expression was positively correlated with IL-1β expression and the number of apoptotic cells. Interestingly, the localization of HZ in the vesicular surfactant of apoptotic pneumocyte was also identified and submitted to be a cause of alveolar resolution abnormality. Thus, HZ triggers monocytes to produce IL-1β and induces pneumocyte type II apoptosis through CARD9 pathway in association with down-regulated E-cadherin, which probably impairs alveolar resolution in malaria-associated ALI.Impact statementThe present work shows the physical and immunomodulatory properties of hemozoin on the induction of pneumocyte apoptosis in relation to IL-1β production through the CARD9 pathway. This occurrence may be a possible pathway for the retardation of lung resolution leading to blood–gas-barrier breakdown. Our findings lead to the understanding of the host–parasite relationship focusing on the dysfunction in ALI induced by HZ, a possible pathway of the recovering lung epithelial retardation in malaria-associated ARDS.
PDGFRB mutation and tyrosine kinase inhibitor resistance in Ph-like acute lymphoblastic leukemia
Authors: Zhang Yingchi , Gao Yufeng , Zhang Hui , Zhang Jingliao , He Fuhong , Hnízda Aleš , Qian Maoxiang , Liu Xiaoming , Gocho Yoshihiro , Pui Ching-Hon , Cheng Tao , Wang Qianfei , Yang Jun J. , Zhu Xiaofan , Liu Xin 
Published: February 2018

Key Points
AGGF1-PDGFRB is a novel oncogenic fusion gene in Ph-like ALL. Genomic profiling and functional studies identified a novel PDGFRB mutation directly related to TKI resistance.
„Muss nur noch kurz die Welt retten.“
Authors: Adloff Frank , Degens Philipp 
Published: February 2018

Zusammenfassung
Der Begriff Philanthrokapitalismus verweist auf die Verschränkung philanthropischer und profitwirtschaftlicher Handlungslogiken. Im Philanthrokapitalismus soll die Effektivität des Stiftungshandelns erhöht und ggf. gleichzeitig Rendite erzielt werden. Der vorliegende Beitrag führt in das Konzept des Philanthrokapitalismus ein, grenzt ihn von herkömmlicher Philanthropie ab und diskutiert einige der ihm inhärenten Probleme. Diese ergeben sich etwa aus dem Fokus auf Effektivität, Unternehmertum und Wettbewerb sowie einer apolitischen Technisierung sozialer Probleme.
Preparation of a synergistically stabilized oil-in-water paraffin Pickering emulsion for potential application in wood treatment
Authors: Jiang Jun , Cao Jinzhen , Wang Wang , Shen Haiying 
Published: February 2018

Abstract
Pickering emulsions (emulsions stabilized by solid-state additives) are attractive as they have strong similarities with traditional surfactant-based emulsions. In this study, an oil-in-water (O/W) paraffin Pickering emulsion system with satisfying stability and small droplet size distribution was developed by hydrophilic silica particles and traditional surfactants as mixed emulsifiers. The droplet morphology and size distribution were observed by optical microscopy and a laser particle analyzer. The emulsion stability was improved and the droplet size was reduced after addition of a suitable amount of silica particles. The silica concentration of 1% showed the optimal effect among all the levels observed (0.1, 0.5, 1 and 2%). Wood was impregnated with the prepared emulsion, and the chemical and morphological properties of the product were investigated by Fourier-transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM) combined with energy-dispersed X-ray analysis (SEM-EDXA). Moreover, the hydrophobicity, thermal properties, surface hardness, axial compression strength (CS) and dynamic mechanical properties were tested. The silica was evenly distributed in the wood cell wall and thus there was a synergistic positive effect from the paraffin and silica in the cell wall leading to better hydrophobicity, improved surface hardness and mechanical properties including the thermal stability.
Determination of selenium during pathogenesis of hepatic fibrosis employing hydride generation and inductively coupled plasma mass spectrometry
Authors: George Joseph 
Published: February 2018

Abstract
Serum and liver selenium levels were studied during the pathogenesis of N-nitrosodimethylamine (NDMA) induced hepatic fibrosis in rats. The degree of fibrosis was assessed with Masson’s trichrome staining and quantifying collagen content in the liver. Lipid peroxides were measured in blood and liver samples and total glutathione and glutathione peroxidase were assayed in the liver tissue to evaluate oxidative stress. Interleukin-6 (IL-6) and transforming growth factor-β1 (TGF-β1) were measured in the serum. Selenium levels were determined using inductively coupled plasma-mass spectrometry (ICP-MS) after acid digestion and hydride generation of selenium. Serial administrations of NDMA produced well-developed fibrosis and early cirrhosis in the liver with 4-fold increase of total collagen content and deposition of collagen fibers. Blood and hepatic lipid peroxides, serum IL-6 and TGF-β1 were significantly increased. There was significant reduction in hepatic glutathione and glutathione peroxidase levels. Serum and liver selenium were remarkably decreased on all the days studied. The results suggest that decreased selenium and glutathione peroxidase contribute to the impairment of cellular antioxidant defense, which in turn results in oxidative stress and trigger pathogenesis of hepatic fibrosis. The study further demonstrated that ICP-MS with hydride generation technique is a reliable and sensitive method for determination of selenium in biological samples.
Body composition in preterm infants with intrauterine growth restriction: a cohort study
Authors: Villela Letícia Duarte , Méio Maria Dalva Barbosa Baker , Gomes Junior Saint Clair S. , de Abranches Andrea Dunshee , Soares Fernanda Valente Mendes , Moreira Maria Elisabeth Lopes 
Published: February 2018

AbstractAims:The comparison of body composition parameters between the small for gestational age (SGA) and appropriate for gestational age (AGA) at term, 1, 3 and 5 months corrected ages in very preterm infants.Methods:This cohort study included 92 preterm infants at term age, younger than 32 weeks or <1500 g, classified in two groups: SGA and AGA. Anthropometry and body composition, estimated by air displacement plethysmography, were evaluated at the corrected ages: term and 1, 3, and 5 months. We used the lean mass/fat mass index (LM/FM) at each time point and the weight, length and head circumference SDS gain between the time points.Results:At term age, the SGA preterm infants had less lean mass (g), fat mass (g) and percent fat mass but a greater LM/FM index than AGA infants (P<0.001). At 1 month corrected age the LM/FM index and percent fat mass between the groups became similar. Lower lean mass persisted up to 3 months in the SGA group [4004 g (3256–4595) vs. 4432 g (3190–6246), P<0.001]. During the first month corrected age, the weight SDS gain was higher in SGA preterm infants when compared to AGA preterm infants. However, the SGA preterm infants remained lighter, shorter and with smaller head circumferences than the AGA preterm infants until 3 months of corrected age.Conclusions:The greater lean tissue deficits and an earlier “catch-up” in fat in the SGA group can reflect growth patterns variability since the early life.
A short review and worldwide list of wild albino rodents with the first report of albinism in Coendou rufescens (Rodentia: Erethizontidae)
Authors: Romero Víctor , Racines-Márquez Calos E. , Brito Jorge 
Published: February 2018

Abstract
Aberrant pelage color patterns such as albinism have been reported in some mammal groups including rodents, but in spite of the group’s richness, the phenomenon is relatively poorly documented in the literature. Albino specimens are reported in <2% of the species of rodents, four records of neotropical species were found (Delomys dorsalis, Heteromys anomalus, Octodon degus, Phyllotis andium). Of New World porcupines (Erethizontidae), albinism was documented only in the North American species Erethizon dorsatum. Here we report the first albino record from the Neotropics for this group, a stump-tailed porcupine (Coendou rufescens) in northern Ecuador.
Pre-Service Teachers’ Resistance to Multicultural Education Courses: The Binary Fear of the Familiar and the Unfamiliar Communities
Authors: Ndemanu Michael Takafor 
Published: February 2018

Abstract
This paper discusses pre-service teachers’ (PSTs) resistance to some of the core concepts of multicultural education in a large Midwestern university. The data collected from document reviews, observations, and interviews with a selected group of PSTs point to cultural-ecological factors as major sources of the resistance. The paper examines these cultural-ecological factors correlating to PSTs’ fear of introducing multicultural concepts in their future suburban schools as well as their fear of cultural incongruity in the the urban schools. The study calls for an intensive and extensive multidimensional field experiences to familiarize PSTs with the unfamiliar cultures while providing them dialogic tools to informally engage their own communities on sensitive topics covered in multicultural education.
Regime switching with structural breaks in output convergence
Authors: Beylunioğlu Fuat C. , Stengos Thanasis , Yazgan M. Ege 
Published: February 2018

Abstract
In this paper, we examine empirically GDP per capita convergence using an approach that explicitly allows for regime switching in the long memory parameter d within the context of a Markov Switching (MS)–ARFIMA framework. As existing methods used in the estimation of standard MS models, such as the EM algorithm are no longer appropriate, we will make use of the Viterbi algorithm to estimate the long memory MS model used by Tsay and Härdle (Tsay, W.-J., and W. K. Härdle. 2009. “A Generalized Arfima Process with Markov-Switching Fractional Differencing Parameter.” Journal of Statistical Computation and Simulation 79: 731–745.). We will classify the output gap series into two regimes, a high d and a low d regime, where a high d close to unity would imply persistence and lack of convergence. By examining the path of d parameter over time which enables us to observe non-convergent behavior in more detail, we find that converging behavior is diminishing over time and divergence is the dominant force.
Similarity Reduction and Exact Solutions of a Boussinesq-like Equation
Authors: Zhang Bo , Hu Hengchun 
Published: February 2018

Abstract
The similarity reduction and similarity solutions of a Boussinesq-like equation are obtained by means of Clarkson and Kruskal (CK) direct method. By using Lie symmetry method, we also obtain the similarity reduction and group invariant solutions of the model. Further, we compare the results obtained by the CK direct method and Lie symmetry method, and we demonstrate the connection of the two methods.
Un nuevo capítulo en la recuperación de la lengua nonuya: testimonio de una experiencia reciente
Authors: Moreno (Sika) Eliécer , Moreno Elias , Gómez Virgelina , Moreno Evelio , Rodríguez Sonia , Gómez Margarita , Moreno Esteban , Moreno Jair , Moreno Kathy , Moreno Blasiney , Moreno Didier , Anibal Nubia , Viasús Quintero Guillermo Alfonso , Romero Cruz Isabel Victoria , Echeverri Juan Alvaro 
Published: February 2018

La lengua nonuya, propia de la amazonia colombiana y perteneciente a la familia lingüística Uitoto, se encuentra actualmente en peligro crítico de extinción debido, entre otros factores, a la drástica reducción demográfica durante la bonanza cauchera y la posterior dispersión de sobrevivientes, así como a la ausencia de transmisión intergeneracional y el consecuente desplazamiento del nonuya por lenguas, tales como: muinane y castellano. Sin embargo, en el contexto en el cual habitan los nonuya actuales, la lengua nativa sigue siendo un marcador fundamental de la identidad étnica, además de ser un eslabón casi perdido de su historia y de su cosmovisión. En tal contexto, y desde la interacción de la academia con este grupo, específicamente con miembros del clan mata de achiote, surge la experiencia de reactivación del uso de la lengua nonuya llevada a cabo en la Comunidad Nonuya de Peña Roja. En el presente artículo recogemos entonces tanto aspectos teóricos como metodológicos que guiaron la experiencia; describimos las actividades realizadas, permitiéndonos evaluar su alcance e impacto; reflexionamos en torno a la revitalización lingüística a partir de este caso particular y proponemos algunas futuras intervenciones que podrían fortalecer el empoderamiento de los nonuya en la recuperación de su lengua ancestral.
Different Strategies to Treat Paroxysmal AF in Patients with Moderate CKD and Severe OSA: a sub group Analysis
Authors: Kiuchi Marcio Galindo , Chen Shaojie 
Published: February 2018

Accentuated sympathetic nerve activity is a strong danger feature for cardiovascular major episodes, such as cerebral and myocardial ischemia/infarction. Peripheric sympathetic nerve activity is emphasized in the hypertensive state, congestive cardiac failure, OSA, heaviness, diabetes, and chronic kidney disease (CKD) subjects. Leastwise a half of individuals with hypertension present augmented sympathetic nerve activity. Our group believes that RSD can reduce AF recurrence in patients with CKD and OSA by modulation of the sympathetic hyperactivity present in these diseases. The goal of this prospective study was to compare the impact of different treatments including CPAP, PVI, RSD, and some combination of them in controlled hypertensive patients with paroxysmal AF, moderate CKD, and severe OSA. Our data suggest that the patients underwent RSD associated to CPAP treatment or PVI, or both of them presented an improvement in the renal function, a decrease in AHI and a lower chance to present AF recurrence than the ones that did not suffer this intervention. Although encouraging, our data are preliminary and need long-term validation in a large population.
Geoenvironmental Analysis for the Delimitation of the Construction waste Disposal Área
Authors: Oliveira Anna Luiza Garção , Nunes Filho Onaldo José , Fiorese Neto Olívio , Amaral Fabrício Borges , Rodrigues Regiane Lima , Mendes Thiago Augusto 
Published: February 2018

Abstract: the intense production of construction and demolition waste (RCCD) in city spaces is a central problem for public management, especially in view of the difficulty in finding suitable places for the disposal of this waste without this poses a risk to the environment. In this sense, the present study aims to identify geoenvironmental aspects (geological, geomorphological and hydrological dynamics) for the evaluation of the terrain with the aid of GIS tools and field expeditions. In order to do so, the methodological stages were systematically systematized. They were: thematic maps, interviews with residents and technicians of the City Hall, monitoring of the deposit formation process and final environmental diagnosis. Finally, it was possible to list and propose structural and non-structural, corrective and mitigating measures for the area of deposit and permanent balance with the environment and with the predominant forms of use and occupation of the region.Análise Geoambiental para Delimitação de Área de Depósito de Resíduos de Construção CivilResumo: a intensa produção de resíduos de construção civil e demolição (RCCD) nos espaços das cidades constitui um problema central para a gestão pública, especialmente diante da dificuldade em se encontrar lugares adequados para deposição destes resíduos sem que isso configure um risco à população . Nesse sentido, o presente estudo visa elencar aspectos geoambientais (geológicos, geomorfológicos e dinâmica hidrológica) para avaliação do terreno com o auxílio de ferramentas SIG e expedições de campo. Para tanto, sistematizou-se, sequencialmente, as etapas metodológicas, sendo elas: elaboração de mapas temáticos, entrevistas com moradores e técnicos da Prefeitura Municipal, acompanhamento do processo de formação do depósito e diagnóstico ambiental final. Por fim, foi possível elencar e propor medidas estruturais e não-estruturais, corretivas e mitigadoras para a área do depósito possibilitando equilíbrio ambiental em consonância com as formas de uso e ocupação predominantes da região.
The use of microarrays for the identification of the origin of genes of avian influenza viruses in wild birds
Authors: Heydarov Rustam N. , Lomakina Natalia F. , Boravleva Elizaveta Yu. , Kholodilov Ivan S. , Gambaryan Alexandra S. , Mikhailovich Vladimir M. , Fesenko Eugene E. 
Published: February 2018

ABSTRACT
Forty-two strains of avian influenza viruses were isolated from the wild waterfowls’ feces in the city of Moscow. These viruses, as well as reference strains and some experimental reassortants, were analyzed by microarrays. The microarrays contained 176 probes to the different segments of influenza virus genome. The microarray helps to determine 1) the hemagglutinin and neuraminidase proteins subtype; 2) the primary structure of the C-terminal sequence of the viral NS1 protein, which serves as a ligand for the PDZ domain; 3) the presence of stop codons in the reading frame of PB1-F2 as well as the N66S substitution in the PB1-F2 viral protein; 4) the presence of the polybasic site for hemagglutinin cleavage. The viruses of the H3N1, H3N6, H3N8, H4N6, H1N1, H5N3, and H11N9 subtypes were identified from the group of wild birds’ isolates. All isolates contained the ESEV sequence at the C-terminus of the NS1 protein and the full-length reading frame for the PB1-F2 protein. The replacement of N66S in PB1-F2 was found in six strains. However, the presence of the ESEV sequence (ligand of PDZ domain) in the NS1 virus protein and the N66S substitution in PB1-F2 did not lead to the pathogenicity of these viruses for mice. All isolates demonstrated high yield growth in chicken embryos and were infectious and immunogenic for mice, but did not induce any clinical symptoms.
Effects of Grafting on Nutrient Element Content and Yield in Watermelon
Authors: CEYLAN Şafak , ALAN Özlem , ELMACI Ömer Lütfü 
Published: February 2018

&nbsp;

This study was conducted to determine the effects of grafting and rootstock-scion
combinations on the yield and nutrient content for both the leaves and fruit of
watermelons. Two watermelon (Citrillus
lanatus (Thunb.) Matsum and Nakai) varieties Crisby and Crimstar were
grafted on to Ferro and RS 841, and the commercial hybrids of Cucurbita maxima x Cucurbita moschata.
Non-grafted plants were used as controls. In the grafted plants the content of K, Mg, Ca, Fe, Cu, Zn and Mn in the leaves and N in fruits
significantly increased when compared to the control. A significant effect was
observed in the rootstocks for the Fe, Cu, Zn content in the leaves and the N,
P, Ca, Cu and Zn content in the fruit. The K and Fe content in the leaf and the
Fe, Cu, Zn and dry matter content in the fruit were also found to be
significant between the varieties. Grafting and rootstock-scion combinations
affect fruit yield. The Crimstar/Ferro combination had the highest yield. Also,
in the grafted plants, the dry matter content of
the fruits had a significant positive correlation with the Ca and Mg content of
the leaves.
Um grito de sobrevivência: agenciamento das bases jurídico-legais de endosso institucional para a guarda e pesquisa de acervos arqueológicos e a militância político-acadêmica das comunidades arqueológica e museológica
Authors: Costa Carlos Alberto Santos 
Published: February 2018

O artigo discute, a luz do institucionalismo histórico, as bases legais para guarda e pesquisa de acervos arqueológicos e os diferentes agentes que operam com esse aparato normativo. O objetivo é demonstrar como os agentes transitórios dessa relação tem mais poder de decisão que aqueles permanentes, bem como essa condição de controle do processo cria certa dificuldade na gestão dos acervos arqueológicos. Num segundo instante, a discussão se amplia, demonstrando como os atores dos campos da arqueologia e da museologia tem se organizado no sentido de questionar e buscar alternativas para correção dos rumos que relacionados a guarda e pesquisa dos acervos arqueológicos, pelo interesse da sociedade.