bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atrioventricular reentrant tachycardia in a child with tricuspid atresia
Authors: Wang Yefeng , Liu Qiming , Deng Xicheng , Xiao Yunbin , Chen Zhi 
Published: February 2019

Abstract

Rationale:
Atrioventricular reentrant tachycardia (AVRT) is the most common supraventricular tachycardia occurring in children. However, in complex congenital heart disease patients with a different heart anatomy and conduction system morphology, accessory pathway modification may be particularly challenging because of distortion of typical anatomic landmarks.

Patient concerns:
A 10-year-old boy with tricuspid atresia and history of bidirectional Glenn operation had recurrent chest distress and palpitation for 3 months. He had multiple hospitalizations for narrow-QRS tachycardia with poor hemodynamic tolerance, despite the use of adenosine and amiodarone.

Diagnoses:
AVRT. Tricuspid atresia with secundum atrial septal defect, large ventricular septal defect, and right ventricular outflow tract stenosis.

Interventions:
Cardiac catheterization, electrophysiological examination, and ablation.

Outcomes:
The child has not had a recurrent AVRT during 6 months of follow-up and is waiting for Fontan operation.

Lessons:
Since there is an increased risk of accessory pathways in patients with tricuspid atresia, all these patients should be checked before the Fontan operation to exclude congenital accessory pathways.
A rare primary Candida parapsilosis infection of the knee joint in a patient without predisposing factors
Authors: Wang Jun , Zhang Zhen , Zhang Miao , Yang Bo , Wang Tengyun , Sun Xuedong , Chen Xiuli , Zhang Min Yi , Guo Zhi Yong , Jiang Xin 
Published: February 2019

Abstract

Rational:
Knee joint infection caused by isolated primary Candida is extremely rare, with only a few cases reported. It occurs most often in patients with predisposing factors (e.g., immunosuppression, malignancy, drug abuse) or fungal invasion during traumatic procedures, including surgery. We report an unusual case of Candida parapsilosis infection in the knee joint with no predisposing factors.

Patient concerns:
A 65-year-old man entered our hospital complaining of persistent pain and mild swelling of the right knee that seriously affected normal walking. There was no obvious cause for his distress.

Diagnosis:
The case was eventually diagnosed as a primary Candida parapsilosis infection which had many diagnostic particularities and difficulties.

Interventions:
Total knee arthroplasty (TKA) was ultimately performed followed by fluconazole coverage.

Outcomes:
The patient showed good clinical performance at the 3- and 6-month follow-up visits and was very satisfied with the therapeutic effect.

Lessons:
If there were suspected symptoms of primary Candida infection cases, imaging and microscopic examinations, tissue cultures, and pathological examination of the puncture knee joint fluid were required.
Observation of changes after peripheral retinal injury by cosmetic laser, using wide-field scanning laser ophthalmoscope
Authors: Kim Rae Young , Ra Ho 
Published: February 2019

Abstract

Rationale:
Increases in cosmetic laser use have led to recent reports of accidental retinal injuries, most of which are limited to the posterior pole. We report a case of peripheral retinal injury caused by a 1064-nm Nd:YAG: neodymium-doped yttrium aluminum garnet.

Patient concerns:
A 27-year-old Asian woman was admitted with scotoma symptoms in her right eye. The patient was a skin care technician. Three days before admission, a laser beam had struck her eye while she was preparing for a laser procedure.

Diagnosis:
During fundus examination, a subretinal hemorrhage with disc diameter (DD) of 4.0 and a preretinal hemorrhage of 2.5 DD in its center were found in the 2 o’clock position of the peripheral retina in the right eye.

Interventions:
We monitored the injury for > 6 months, first using fluorescein angiography, then wide-field scanning laser ophthalmoscopy and optical coherence tomography. Oral steroids and vitamins were administered.

Outcomes:
During the 6-month follow-up period, blood from the initial sub- and preretinal hemorrhage, as well as vitreous hemorrhage, were all absorbed. Retinal detachment was not observed as scar formation and adhesions had occurred. No interventions were considered necessary.

Lessons:
When treating a patient who has experienced laser eye injury, the possibility of peripheral retinal injury should be considered. Peripheral retinal injury caused by 1064-nm Nd:YAG: neodymium-doped yttrium aluminum garnet has a relatively good prognosis, suggesting that it will not progress to retinal detachment.
The use of nonthoracoscopic Nuss procedure for the correction of pectus excavatum by trans-esophageal echocardiography monitoring
Authors: Xu Bing , Xu Ting , Wang Shan , Li Wenhua , He Taozhen , Liu Wenying 
Published: February 2019

Abstract
This study was aimed to review the current experience regarding the correction of pectus excavatum by Nuss procedure with nonthoracoscopic assistance using trans-esophageal echocardiography monitoring.
A total of 172 patients with pectus excavatum were surgically treated from August 2011 to August 2016. The sample size comprised 131 boys and 41 girls and the average age was 13 years and 2 months. A total of 144 cases were initially operated on, whereas 13 subjects exhibited postoperative recurrence following Ravitch repair of a pectus excavatum deformity and 15 cases experienced a history of median sternotomy. The intraoperative Haller index ranged from 3.6 to 14.2 (mean 4.1). The intraoperative TEE monitoring was conducted with middle-esophageal 4-champer view and middle-esophageal Aortic short axis view to detect the injury of heart and of the large vessels by the introducer and Nuss steel bars.
The operation conducted in all patients was successful in the absence of severe complications. The time of operation ranged from 38 to 80 minutes (mean 50 minutes). The bleeding volume during the procedure was between 10 and 40 mL (mean 15 mL). The time from operation to discharge was from 5 to 7 days (mean 6 days). Pneumothorax occurred in 25 cases following the termination of the operation, including 9 cases of needle puncture aspiration and 6 cases of closed drainage. Pleural effusion occurred in 4 cases. No patients suffered from wood infection. Effusion occurred in 9 cases following 6 to 23 months, whereas dressing changes and surgical debridement were evident in 2 and 7 cases, respectively. The bars were removed in 82 of the 172 patients within 3 years. The progression of the thoracic wall was assessed for the period of 8 to 68 months following the surgery, during the follow-up period. The average time period of follow-up was 32 months.
Nuss procedure with nonthoracoscopic assistance with trans-esophageal echocardiography monitoring for the correction of pectus excavatum was safe for all of the cases investigated. It exhibited lesser trauma and required a shorter time period.
The comparison of cognitive function and risk of dementia in CKD patients under peritoneal dialysis and hemodialysis
Authors: Tian Xiaolin , Guo Xiaokun , Xia Xiaoshuang , Yu Haibo , Li Xin , Jiang Aili 
Published: February 2019

Abstract

Backgrounds:
Cognitive functions (CF) decline has been reported in end-stage renal disease (ESRD) patients. However, the influence of dialysis modalities on CF has not been investigated systematically.

Methods:
A systematic literature search was conducted in MEDLINE, Embase, Cochrane library and unpublished database Clinicaltrials.gov to identify the studies comparing the cognitive functions or risk of dementia between hemodialysis (HD) and peritoneal dialysis (PD). After data extraction, quality of studies was assessed using the Newcastle-Ottawa scale. Both qualitative and quantitative analyses were performed.

Results:
After study inclusion, totally 15 cohort or cross-sectional studies were included, comparing the cognitive functions using neuropsychological tests and covering the executive function, memory, orientation, attention, etc. By qualitative analysis, it showed that more studies are inclined to PD compared with HD with better cognitive functions. By quantitative analysis, it showed that PD showed better performance in the tests of Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), stroop interference test and exhibited lower risk of dementia compared with HD.

Conclusions:
In this meta-analysis, we draw preliminary conclusion that patients treated with PD had better cognitive functions and lower dementia risk compared with patients with HD. Still more large-scale and well-conducted prospective cohort studies are needed to draw more convincing conclusions.
A systematic review of clinical outcomes and radiotherapy-associated toxicity in multicatheter accelerated partial breast irradiation
Authors: Lv Yang , He Lin , Wang Chao , Zhang Lijiu , Zhang Biyuan , Song Yuhua 
Published: February 2019

Abstract

Background:
To integrate relevant clinical data of multicatheter accelerated partial breast irradiation (mAPBI) for reaching a comprehensive conclusion.

Methods:
We did 3 meta-analyses for clinical outcomes including 1740 women from 4 articles, for acute radiotherapy (RT)-associated toxicity including 1255 patients from 5 articles, and for late RT-related toxicity involving 1565 patients from 9 papers. Clinical outcomes analyses were stratified by molecular subtypes, lymph nodes status, receptor status, and human epidermal growth factor receptor 2 (HER2) status.

Results:
For the Luminal A/B phenotypes, the disease relapse and failure in survival significantly decreased when compared with triple negative (TN)/HER2-amplified subtypes (P < .00001). The 5-year regional nodal recurrence (RNR), 5-year distant metastasis-free survival (DMFS) and 5-year disease free-survival (DFS) of TN patients were significantly superior to HER2-overexpression patients (P < .00001). The 5-year cause-specific survival (CSS), 5-year DMFS and 5-year overall survival (OS) in women with lymph nodes-negative were significantly improved versus patients with lymph nodes-positive (P = .0001). Conversely, the positive status of HER2 compared with negative one significantly increased the rate of local recurrence (LR) (P = .02). For acute toxicity, the morbidity of dermatitis was significantly higher than hematoma and implant infection (P = .01, P < .0001, respectively). For late toxicity, the occurrences of fibrosis (32%) and telangiectasia (14%) were significantly higher than other complications (P < .0001).

Conclusion:
HER2-enriched subtype compared with other subtypes has significantly increased disease relapse and failure in survival. HER2-positive status is positively associated with an increased incidence of LR. Dermatitis is the most common acute RT-related toxicity and fibrosis is the first rife late RT-related toxicity.
Effect of Kinesio taping on electromyographic activity of leg muscles during gait in children with developmental coordination disorder
Authors: Yam Timothy Tsz Ting , Wong Man Sang , Fong Shirley Siu Ming 
Published: February 2019

Abstract

Objective:
This study aimed to evaluate the effectiveness of Kinesio tape (KT) on lower limb muscle activation pattern in children with developmental coordination disorder (DCD) during walking.

Design:
A parallel-group randomized controlled trial.

Setting:
University laboratory setting.

Participants:
Twenty-five children with DCD were randomly allocated to the KT group (mean age = 7.97 years) and 24 to the control group (mean age = 8.04 years).

Intervention:
KT group received KT application to the quadriceps and gastrocnemius muscles whereas the control group received no intervention.

Measurements:
Peak muscle activation (in percentage of maximal voluntary isometric contraction [%MVIC]) in the lower limbs during gait was measured by means of surface electromyography, electrogoniometry, and foot contact switches.

Results:
Gastrocnemius medialis activation during mid stance (23.46%MVIC, 95% CI = −32.53, −14.39) and late stance phases (3.25%MVIC, 95% CI = −5.67, −0.81) of gait increased after the application of KT in the KT group compared to baseline values. The KT group demonstrated 26.87%MVIC (95% CI = 26.87, 7.11) higher gastrocnemius medialis muscle peak activation during mid stance phase at post-test when compared with the control group. Moreover, gastrocnemius medialis and biceps femoris muscle peak activation during loading response decreased by 8.36%MVIC (95% CI = 2.71, 14.02) and 3.54%MVIC (95% CI = 1.08, 6.01), respectively, in the control group overtime.

Conclusions:
The application of KT on children with DCD had an increased gastrocnemius medialis muscle activation during stance phase. KT could be incorporated into gait re-education programmes to facilitate muscle contraction in these children.
Efficacy of transsphenoidal surgery for pituitary tumor
Authors: Wang Wei-Feng , Yang Lin-Hong , Han Lin , Li Ming-Jun , Xiao Jian-Qi 
Published: February 2019

Abstract

Background:
This systematic review aims to assess the efficacy and safety of transsphenoidal surgery (TPS) for patients with a pituitary tumor (PT).

Methods:
We will retrieve the following electronic databases for randomized controlled trials or case–control studies to assess the effect and safety of TPS for PT: Cochrane Library, EMBASE, MEDLINE, Cumulative Index to Nursing and Allied Health Literature, Web of Science, Allied and Complementary Medicine Database, and Chinese Biomedical Literature Database. Each database will be retrieved from the inception to December 20, 2018. The entire process consists of the study selection, data collection, methodology quality assessment, data pooled, and meta-analysis performance. The methodology quality will be assessed by using Cochrane risk of bias tool. The data pooled and meta-analysis will be conducted by using RevMan 5.3 software.

Results:
This study will evaluate the efficacy and safety of TPS for PT. The primary outcome includes total tumor resection rate. The secondary outcomes consist of quality of life, total tumor resection rate, postoperative complication rate, and the rate of functional tumor hormone levels.

Conclusion:
The expected results may provide up-to-date evidence of TPS for the treatment of PT.

PROSPERO registration number:
PROSPERO CRD42018120194.
Isolated third nerve palsy with pupillary involvement resulting from carotid-cavernous sinus fistula
Authors: Lin Hsin-Le , Hu Tzu-Te 
Published: February 2019

Abstract

Rationale:
Isolated third nerve palsy with pupillary involvement caused by a posterior drainage carotid-cavernous sinus fistula (CCF) is relatively rare. Diagnosis of a posterior drainage CCF can often be delayed due to its unapparent congestive signs.

Patient concerns:
Here, we present the case of a young male patient with right-sided CCF, who presented with right-side headache and partial third nerve palsy with pupillary involvement. The diagnosis was confirmed using time-of-flight magnetic resonance angiography (TOF-MRA) and digital subtraction angiography (DSA).

Diagnoses:
A right-sided CCF was detected, which was primarily supplied by the dural branch of the right middle meningeal artery and venous drainage into the right inferior petrosal sinus.

Interventions:
The patient was treated with transarterial coil embolization.

Outcomes:
At 2 months, ride-side headache was significantly improved and ptosis and limited extraocular muscle movement were partially resolved.

Lessons:
CCF might not always present with ocular congestion. Although uncommon, white-eye and painful third nerve palsy with pupillary involvement may be caused by a posterior drainage CCF.
Submucosal 1-tunnel endoscopic resection for treating upper gastrointestinal multiple submucosal tumor originating from the muscularis propria layer
Authors: Wang Haiqin , Tan Yuyong , Huo Jirong , Liu Deliang 
Published: February 2019

Abstract
To explore the feasibility and efficacy of submucosal 1-tunnel endoscopic resection (1-tunnel STER) for the treatment of multiple upper gastrointestinal submucosal tumors (GI-SMTs) originating from the muscularis propria (MP) layer.
A total of 12 patients with multiple upper GI-SMTs (no less than 2 SMTs) who underwent 1-tunnel STER from April 2013 to October 2017 were included. Clinical data on general characteristics, operation-related parameters, adverse events, and follow-up results were recorded and analyzed.
All 12 patients underwent 1-tunnel STER successfully, and the mean operation time was 92.1 ± 40.8 minutes. A total of 30 SMTs were resected, out of which 27 were in the esophagus and 3 were in the stomach. The mean diameter was 15.0 ± 8.2 mm (range, 3–38 mm). All the SMTs were resected en bloc uneventfully. The SMTs comprised 28 leiomyomas and 2 gastric stromal tumors (low risk). No recurrence was noticed during a mean follow-up of 24.9 ± 15.3 months (range, 1–52 months).
One-tunnel STER may serve as a feasible and effective technique for the treatment of multiple upper GI-SMTs originating from the MP layer. A large-scale prospective study is warranted for a confirmative conclusion.
Association of serum high mobility group box 1 levels with disease activity and renal involvement in patients with systemic vasculitis
Authors: Zhu Bin , Li Nanfang , Zhu Qing , Wu Ting , Heizati Mulalibieke , Wang Guoliang , Yao Xiaoguang , Luo Qin , Liu Shasha , Liu Shanshan , Hong Jing 
Published: February 2019

Abstract
High mobility group box 1 (HMGB1) is a kind of proinflammatory mediator that acts as an alarmin when released by dying, injured or activated cells. Previous studies have reported that HMGB1 are closely linked to antineutrophil cytoplasmic antibody-associated vasculitis (AAV). The present study aimed to evaluate whether serum HMGB1 levels were associated with systemic vasculitis (VAs).
The study population consisted of 51 patients with VAs, 46 patients with essential hypertension (EH) and 46 healthy controls (HC). Thirty-five patients with VAs had in active stage and 16 patients with VAs in an inactive stage. Furthermore, 31 patients with VAs had renal involvement, the other 20 patients were selected for without renal involvement. Serum HMGB1 levels were measured by enzyme-linked immunosorbent assay. Associations between serum HMGB1 levels with clinical and laboratory parameters were analyzed.
Serum HMGB1 levels in patients with VAs were significantly higher than in EH and HC (all P < .05), and no difference regarding serum HMGB1 levels could be found between EH and HC (P = .208). Serum HMGB1 levels in VAs patients with active stage were significantly higher than those in HC and VAs patients with inactive stage (all P < .05). Patients with renal involvement and non-renal involvement had increased HMGB1 levels compared with HC (all P < .05). In addition, serum HMGB1 levels were significantly higher in patients with renal involvement compared with non-renal involvement patients (P = .001). Correlation analysis showed that serum HMGB1 levels were positive significant correlated with the Birmingham Vasculitis Activity Score, hypersensitive C reactive protein (Hs-CRP), serum creatinine (Scr) and 24-hour proteinuria (all P < .05). Among the subsets of VAs, serum HMGB1 levels were significantly higher in AAV, polyarteritis nodosa (PAN) and takayasu arteritis (TA) than in HC (all P < .05). More interestingly, serum HMGB1 were significantly higher in patients with PAN compared with AAV and TA patients (all P < .05). Furthermore, there was positive correlation between serum HMGB1 levels and Hs-CRP, Scr, and 24-hour proteinuria in patients with PAN (all P < .05).
Serum HMGB1 levels are increased in patients with VAs compared with HC and EH and can reflect the disease activity and renal involvement.
Inspiring Writing in Nursing
Authors: Ansryan Lianna Z. , Marshall Caroline , Aronow Harriet Udin , Chan Alice , Coleman Bernice 
Published: February 2019

Background:
Hospitals are constantly involved in quality improvement and research projects investing considerable money, time, and effort in supporting these projects; however, there is not always a strong enough focus on publishing the results. The challenge lies in engaging clinicians to publish their work. One of the hallmarks of the clinical nurse specialist is mentoring, and this has led to the creation of our Inspiring Writing in Nursing (IWIN) program.

Purpose:
The goal of IWIN cohort was to engage and promote publication submissions from frontline clinicians. The 18-member Nursing Research and Evidence-Driven Practice Council (NR-EDPC) supports more than 3000 nurses in quality and research projects. Two senior librarians support our council and staff. In 2014, we launched our first IWIN cohort to mentor nurses in writing and submitting for publication.

Evaluation:
The NR-EDPC motto “meet them where they are” applies to both location and level of research/EDPC knowledge and skill. An Annual Nursing Research Conference showcases the products of nursing science. The first cohort of IWIN enrolled 11 mentees, and after a yearlong journey, we submitted 5 of 11 manuscripts, 3 withdrew, and 3 are still under revisions. From the 5 submissions, 3 were published, 1 was rejected, and 1 is currently under revision.

Discussion:
With support and the infrastructure of our NR-EDPC, we are launching our second IWIN cohort.
Prevention of Cesarean Delivery Surgical Site Infections
Authors: Shea Sarah K. , Soper David E. 
Published: February 2019

Importance
Surgical site infection (SSI) is a common complication of cesarean delivery. Seen in up to 12% of cesarean deliveries, it is a major cause of prolonged hospital stay and a burden to the healthcare system. Interventions and techniques must be identified to decrease the risk of cesarean delivery SSIs.

Objective
We review the categories of SSI, current studies that have focused on various interventions to decrease SSI, and preoperative, intraoperative, and postoperative recommendations for cesarean delivery SSI prevention.

Evidence Acquisition
A thorough search of PubMed for all current literature was performed. Various surgical interventions and techniques were reviewed. We included studies that looked at preoperative, intraoperative, and postoperative interventions for SSI prevention.

Results
We have summarized several surgical interventions and techniques as well as current consensus statements to aid the practitioner in preventing SSIs after cesarean delivery.

Conclusions and Relevance
Upon analysis of current data and consensus statements pertaining to cesarean deliveries, there are certain preoperative, intraoperative, and postoperative interventions and techniques that can be recommended to decrease the risk of cesarean delivery SSI.

Target Audience
Obstetricians and gynecologists; family physicians

Learning Objectives
After completing this CME activity, physicians should be better able to evaluate preoperative considerations when preparing for a cesarean delivery; distinguish the recommended antiseptic choices for preoperative cleansing/prepping before cesarean delivery; propose the appropriate use of prophylactic antibiotics for prevention of cesarean delivery SSI; and select the surgical techniques that have been shown to decrease the risk of cesarean delivery SSI.