bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fuelling conditions at staging sites can mitigate Arctic warming effects in a migratory bird
Authors: Rakhimberdiev Eldar , Duijns Sjoerd , Karagicheva Julia , Camphuysen Cornelis J. ,   VRS Castricum, van Loon Andre , Wijker Arnold , Keijl Guido , Levering Henk , Jan Visser  , Heemskerk Leo , Knijnsberg Luc , van Roomen Marc , Ruiters Paul , Admiraal Piet , Veldt Piet , Reijnders Richard , Beentjes Walter , Dekinga Anne , Dekker Rob , Gavrilov Anatoly , ten Horn Job , Jukema Joop , Saveliev Anatoly , Soloviev Mikhail , Tibbitts T. Lee , van Gils Jan A. , Piersma Theunis 
Published: October 2018

AbstractUnder climate warming, migratory birds should align reproduction dates with advancing plant and arthropod phenology. To arrive on the breeding grounds earlier, migrants may speed up spring migration by curtailing the time spent en route, possibly at the cost of decreased survival rates. Based on a decades-long series of observations along an entire flyway, we show that when refuelling time is limited, variation in food abundance in the spring staging area affects fitness. Bar-tailed godwits migrating from West Africa to the Siberian Arctic reduce refuelling time at their European staging site and thus maintain a close match between breeding and tundra phenology. Annual survival probability decreases with shorter refuelling times, but correlates positively with refuelling rate, which in turn is correlated with food abundance in the staging area. This chain of effects implies that conditions in the temperate zone determine the ability of godwits to cope with climate-related changes in the Arctic.
Structural basis for arginine glycosylation of host substrates by bacterial effector proteins
Authors: Park Jun Bae , Kim Young Hun , Yoo Youngki , Kim Juyeon , Jun Sung-Hoon , Cho Jin Won , El Qaidi Samir , Walpole Samuel , Monaco Serena , García-García Ana A. , Wu Miaomiao , Hays Michael P. , Hurtado-Guerrero Ramon , Angulo Jesus , Hardwidge Philip R. , Shin Jeon-Soo , Cho Hyun-Soo 
Published: October 2018

AbstractThe bacterial effector proteins SseK and NleB glycosylate host proteins on arginine residues, leading to reduced NF-κB-dependent responses to infection. Salmonella SseK1 and SseK2 are E. coli NleB1 orthologs that behave as NleB1-like GTs, although they differ in protein substrate specificity. Here we report that these enzymes are retaining glycosyltransferases composed of a helix-loop-helix (HLH) domain, a lid domain, and a catalytic domain. A conserved HEN motif (His-Glu-Asn) in the active site is important for enzyme catalysis and bacterial virulence. We observe differences between SseK1 and SseK2 in interactions with substrates and identify substrate residues that are critical for enzyme recognition. Long Molecular Dynamics simulations suggest that the HLH domain determines substrate specificity and the lid-domain regulates the opening of the active site. Overall, our data suggest a front-face SNi mechanism, explain differences in activities among these effectors, and have implications for future drug development against enteric pathogens.
Definite photon deflections of topological defects in metasurfaces and symmetry-breaking phase transitions with material loss
Authors: Sheng Chong , Liu Hui , Chen Huanyang , Zhu Shining 
Published: October 2018

AbstractCombination of topology and general relativity can lead to some profound and farsighted predictions. It is well known that symmetry breaking of the Higgs vacuum field in the early universe possibly induced topological defects in space-time, whose nontrivial effects can provide some clues about the universe’s origin. Here, by using an artificial waveguide bounded with rotational metasurface, the nontrivial effects of a topological defect of spacetime are experimentally emulated. The photon deflection in the topological waveguide has a robust definite angle that does not depend on the location and momentum of incident photons. This is remarkably different from the random optical scattering in trivial space. By including material loss such a topological effect can be well understood from the symmetry breaking of photonic modes. Our technique provides a platform to investigate topological gravity in optical systems. This method can also be extended to obtain many other novel topological photonic devices.
DNA engineered micromotors powered by metal nanoparticles for motion based cellphone diagnostics
Authors: Draz Mohamed Shehata , Kochehbyoki Kamyar Mehrabi , Vasan Anish , Battalapalli Dheerendranath , Sreeram Aparna , Kanakasabapathy Manoj Kumar , Kallakuri Shantanu , Tsibris Athe , Kuritzkes Daniel R. , Shafiee Hadi 
Published: October 2018

AbstractHIV-1 infection is a major health threat in both developed and developing countries. The integration of mobile health approaches and bioengineered catalytic motors can allow the development of sensitive and portable technologies for HIV-1 management. Here, we report a platform that integrates cellphone-based optical sensing, loop-mediated isothermal DNA amplification and micromotor motion for molecular detection of HIV-1. The presence of HIV-1 RNA in a sample results in the formation of large-sized amplicons that reduce the motion of motors. The change in the motors motion can be accurately measured using a cellphone system as the biomarker for target nucleic acid detection. The presented platform allows the qualitative detection of HIV-1 (n = 54) with 99.1% specificity and 94.6% sensitivity at a clinically relevant threshold value of 1000 virus particles/ml. The cellphone system has the potential to enable the development of rapid and low-cost diagnostics for viruses and other infectious diseases.
Hidden hearing loss selectively impairs neural adaptation to loud sound environments
Authors: Bakay Warren Michael Henry , Anderson Lucy Anne , Garcia-Lazaro Jose Alberto , McAlpine David , Schaette Roland 
Published: October 2018

AbstractExposure to even a single episode of loud noise can damage synapses between cochlear hair cells and auditory nerve fibres, causing hidden hearing loss (HHL) that is not detected by audiometry. Here we investigate the effects of noise-induced HHL on functional hearing by measuring the ability of neurons in the auditory midbrain of mice to adapt to sound environments containing quiet and loud periods. Neurons from noise-exposed mice show less capacity for adaptation to loud environments, convey less information about sound intensity in those environments, and adaptation to the longer-term statistical structure of fluctuating sound environments is impaired. Adaptation comprises a cascade of both threshold and gain adaptation. Although noise exposure only impairs threshold adaptation directly, the preserved function of gain adaptation surprisingly aggravates coding deficits for loud environments. These deficits might help to understand why many individuals with seemingly normal hearing struggle to follow a conversation in background noise.
Biomechanics show stem cell necessity for effective treatment of volumetric muscle loss using bioengineered constructs
Authors: Quarta Marco , Cromie Lear Melinda J. , Blonigan Justin , Paine Patrick , Chacon Robert , Rando Thomas A. 
Published: October 2018

AbstractDespite the regenerative capacity of muscle, tissue volume is not restored after volumetric muscle loss (VML), perhaps due to a loss-of-structural extracellular matrix. We recently demonstrated the structural and functional restoration of muscle tissue in a mouse model of VML using an engineered “bioconstruct,” comprising an extracellular matrix scaffold (decellularized muscle), muscle stem cells (MuSCs), and muscle-resident cells (MRCs). To test the ability of the cell-based bioconstruct to restore whole-muscle biomechanics, we measured biomechanical parameters in uninjured muscles, muscles injured to produce VML lesions, and in muscles that were injured and then treated by implanting either the scaffolds alone or with bioconstructs containing the scaffolds, MuSCs, and MRCs. We measured the active and passive forces over a range of lengths, viscoelastic force relaxation, optimal length, and twitch dynamics. Injured muscles showed a narrowed length-tension curve or lower force over a narrower range of muscle lengths, and increased passive force. When treated with bioconstructs, but not with scaffolds alone, injured muscles showed active and passive length-tension relationships that were not different from uninjured muscles. Moreover, injured muscles treated with bioconstructs exhibited reduced fibrosis compared to injured muscles either untreated or treated with scaffolds alone. The cell-based bioconstruct is a promising treatment approach for future translational efforts to restore whole-muscle biomechanics in muscles with VML lesions.
Dynamic refractive index distribution measurement of dynamic process by combining dual-channel simultaneous phase-shifting interferometry and total internal reflection
Authors: Zhou Yunfei , Zou Haoren , Zhong Liyun , Li Jiaosheng , Li Bingbo , Tian Jindong , Lu Xiaoxu 
Published: October 2018

AbstractWe propose and demonstrate a novel method to measure dynamic refractive index distributions using a combination of total internal reflection (TIR) and dual-channel simultaneous phase-shifting interferometry (DCSPSI). First, a right-angle prism is introduced into the DCSPSI system, the reflection phase variation induced by TIR, which contains the refractive index information of tested sample, can be achieved by the spatial carrier-frequency phase-shifting algorithm from a pair of interferograms with the phase shifts of π/2 captured by DCSPSI system. Second, based on the relationship between the reflection phase variation and the refractive index, the 2D refractive index distribution can be calculated easily. Importantly, the proposed TIR-DCSPSI method will supply a useful tool for dynamic refractive index distribution measurement of dynamic process, such as the droplet evaporation, mutual solubilization and diffusion of different droplets, cell culture, colloid curing, etc.
Microglia induces Gas1 expression in human brain tumor-initiating cells to reduce tumorigenecity
Authors: Sarkar Susobhan , Poon Candice C. , Mirzaei Reza , Rawji Khalil S. , Hader Walter , Bose Pinaki , Kelly John , Dunn Jeffrey F. , Yong V. Wee 
Published: October 2018

AbstractWe reported previously that microglia decreased the growth of human brain tumor-initiating cells (BTICs). Through microarray analyses of BTICs exposed in vitro to microglia, we found the induction of several genes ascribed to have roles in cell cycle arrest, reduced cell proliferation and differentiation. Herein, we tested the hypothesis that one of these genes, growth arrest specific 1 (Gas1), is a novel growth reduction factor that is induced in BTICs by microglia. We found that microglia increased the expression of Gas1 transcript and protein in glioblastoma patient-derived BTIC lines. Using neurosphere assay we show that RNAi-induced reduction of Gas1 expression in BTICs blunted the microglia-mediated BTIC growth reduction. The role of Gas1 in mediating BTIC growth arrest was further validated using orthotopic brain xenografts in mice. When microglia-induced Gas1-expressing BTIC cells (mGas1-BTICs) were implanted intra-cranially in mice, tumor growth was markedly decreased; this was mirrored in the remarkable increase in survival of mGas1-BT025 and mGas1-BT048 implanted mice, compared to mice implanted with non-microglia-exposed BTIC cells. In conclusion, this study has identified Gas1 as a novel factor and mechanism through which microglia arrest the growth of BTICs for anti-tumor property.
Angle-insensitive narrowband optical absorption based on high-Q localized resonance
Authors: Zhu Xiya , Fu Jichao , Ding Fei , Jin Yi , Wu Aimin 
Published: October 2018

AbstractStrong optical absorption can be achieved easily based on an array of subwavelength localized resonators. The absorption bandwidth is typically wide since subwavelength metallic resonators are limited by a low quality factor (Q) due to their large material loss and so do dielectric counterparts owing to their weak photon binding. Here, an angle-insensitive narrowband optical absorber is suggested, which consists of subwavelength dielectric cavities buried inside a metal. Within each cavity, a special resonant mode of high Q can be supported, which is absorbed slowly by the metal walls as the electric field is concentrated at the cavity center and leaks slowly into the free space due to the blocking of the top metal film covering the cavities. Such a mode is excited to trap the incident wave in the optical absorption. When low-loss silver is used, one can obtain ultra-narrowband absorption with Q up to 487. At lower optical frequencies, the metal film needs to be punctured so that the incident wave can couple into the cavities effectively. The suggested absorption method may find its promising prospect in thermal radiation, photonic detection, optical sensing, and so on.
Chiari Type I Malformation Associated With Verbal Fluency Impairment
Authors: Lázaro Esther , García Maitane , Ibarrola Ane , Amayra Imanol , López-Paz Juan Francisco , Martínez Oscar , Pérez Manuel , Berrocoso Sarah , Al-Rashaida Mohammad , Rodríguez Alicia Aurora , Fernández Paula , Luna Paula María 
Published: October 2018

Purpose
Chiari malformation (CM) Type I is a rare disorder that implies an anomaly in the craniocervical junction, where one or both cerebellar tonsils are displaced below the foramen magnum into the cervical spinal channel. Research carried out regarding cognitive symptoms such as verbal fluency is scarce. The aim of this study was to investigate whether verbal fluency is impaired in a CM clinical group compared to a group of healthy control individuals while controlling for depression and anxiety symptomatology.

Method
For this purpose, 101 individuals were enrolled to take part in the study (51 CM, 50 healthy controls). The Controlled Oral Word Association Test (Benton, de Hamsher, & Sivan, 1983) and the Hospital Anxiety and Depression Scale (Zigmond & Snaith, 1983) were administered.

Results

Results showed significantly lower scores for the CM group in verbal fluency compared to the control group (
p
< .005). After performing an analysis of covariance to eliminate depression and anxiety symptomatology tendencies, it was observed that verbal fluency could not be predicted by this variable (
p
> .005).

Conclusions
From the results of this study, it can be concluded that people suffering from CM exhibit less verbal fluency than healthy control individuals and that this difference is not caused by depression or anxiety.
Influence of pressure on the properties of AlN deposited by DC reactive magnetron sputtering on Si (100) substrate
Authors: Li Tao , Han Jun , Xing Yanhui , Deng Xuguang , Li Junshuai , Zhang Li , Shi Fengfeng , Yu Lun , Sun Chi , Zhang Xiaodong , Zhang Baoshun 
Published: October 2018

Preferred (002)‐oriented aluminium nitride (AlN) films by direct‐current (DC) magnetron sputtering on Si (100) substrate were prepared at various deposition pressure (0.12–0.5 Pa). The influence of pressure on the surface morphology, crystal structure and optical properties of AlN thin films was discussed the with the methods of X‐ray diffraction, atomic force microscopy and stress analyser, respectively. Optical properties were studied by ellipsometer and Fourier transform infrared spectrometer. It was observed that the AlN films tended to be preferred (002)‐oriented when the pressure was decreased and the value of full width at half maximum is 0.325° when the pressure was kept at 0.12 Pa. the tensile stress, refractive index, and the density of Al–N bonds decreased with increasing the sputtering pressure from 0.12 to 0.5 Pa. This work demonstrated the influence of sputtering pressure on the structural and optical properties of the AlN films deposited on Si (100) substrate, the gallium nitride epitaxial film on Si (100) substrate was expected to be realised using sputtered AlN as the buffer layer.
Experimental and computational dynamic analysis of the foam concrete as a sub-base layer of the pavement structure
Authors: Valaskova Veronika , Vlcek Jozef , Drusa Marian 
Published: October 2018

Dynamic properties of the new materials represent the actual problem, which is solved at many departments in the world at this time. Foam concrete (FC) is a material that has wide application in the civil engineering structures. Currently, it's mainly used in the floor structures of the buildings but its usability can be much wider thanks to its specific properties. The foam concrete contains closed air pores, what achieves its low volume weight (density) and saving of material inputs. It's a building material with good mechanical properties and low thermal conductivity and at the same time with high-tech processing.
Nowadays, a research aimed at the application of the foam concrete in the pavement structures takes place at the University of Zilina. Foam concrete could be utilized as a sub-base layer at the road reconstructions, excavations or as a regular layer of the new constructed pavements.
The submitted paper is dedicated to the numerical simulation based on the Finite element method (FEM) in pursuance of the outputs of the experimental investigation of the dynamic effect on the pavement structure which contains the foam concrete layer. Obtained dynamic parameters will be a background for the pavement design using the foam concrete.
What is it in Swedish?
Authors: Stoewer Kirsten 
Published: October 2018

Abstract
The present chapter investigates teacher-initiated translation requests as spontaneous vocabulary teaching during English mother tongue instruction in Sweden. The collection-based analysis draws on a corpus of 30 hours (11 weeks) of video-recordings of compulsory school-age students. The analysis shows how the teacher routinely draws on the local availability of two shared languages to accomplish a variety of actions: to check students’ comprehension of topicalised vocabulary; to engage the entire cohort; to perform medium repair; and to prompt student production of the target language. The findings may be of relevance for numerous types of bi- and multilingual settings, where language alternation serves to augment the teaching and learning of languages as well as other subject matter.
L1/L2 alternation practices in students’ task planning
Authors: Kunitz Silvia 
Published: October 2018

Abstract
This conversation analytic study explores the language alternation patterns enacted by students of Italian as a Foreign Language as they engage in planning a classroom presentation. The data consist of 13 planning sessions conducted by two groups of students enrolled in a third semester course and two groups of students enrolled in a sixth semester course at a US university. The analysis shows how the participants achieve a local interactional order (Cromdal 2005) where the alternation between the L1 and the L2 embodies the distinction between planning process (in L1-English) and planning product (in L2-Italian) and achieves the transition between such components of the planning activity. Overall, the study demonstrates that language alternation is a discursive skill that constitutes a resource for planning for students at different proficiency levels.
Making teacher talk comprehensible through language alternation practices
Authors: Filipi Anna 
Published: October 2018

Abstract
This study reports the ways in which students and their teacher co-manage the interactional problems resulting from a lack of understanding of the teacher’s instructions produced in the second language (L2) through language alternation practices. The study draws on data from two Italian as a Foreign Language lessons in an Australian high school involving students aged 13–14 at an A2 (CEFR) level of proficiency. Analysis shows: (1) how the teacher ascribed “expected” knowledge states to students as a class and to students as individuals; (2) how the teacher packaged her instructions multimodally and switched to students’ first language (L1) only as a last resort; and (3) how students availed themselves of serendipitous opportunities presented in the context to build their understanding of Italian as the medium of instruction in order to successfully answer the teacher’s questions or to follow instructions without having to admit that they did not know what was being asked of them.
Evaluation of loading and hauling technology for improving andesite mine performance
Authors: Adiansyah J S , Payadi K , Alpiana  , Rahmawati D 
Published: October 2018

Abstract
This paper evaluates the utilization of loading and hauling technology at andesite mine using cycle time and match factor methods. One mine site operated by PT. Anugerah Karya Agra Sentosa was taken as a case study. PT. Anugerah Karya Agra Sentosa located in Mujahiddin Village, Plampang Sub-district, West Sumbawa Regency is an andesite mining using open pit system with quarry type method. Mechanical equipment that operates is one unit Excavator (Kobelco SK 200) capacity 0.9 m3 and five units Dump Truck (Toyota Dyna 130 HT) with bucket capacity 3.6 m3. The analysis results found that the average cycle time for loading equipment was 0.54 minutes while the average cycle time for hauling equipment was 14.58 minutes. Recalculation for match factor (MF=1) resulted in additional of two hauling equipments from five units to seven units (Dump Truck).
Six-Month Comparative Analysis Monitoring the Progression of the Largest Diameter of the Sweating Inhibition Halo of Different Botulinum Toxins Type-A
Authors: da Costa Adilson , Pereira Elisangela Samartin Pegas , de Oliveira Pereira Margareth , dos Santos Felipe Borba Calixto , Fávaro Raquel , de Matos Lissa Sabino , Tannous Thaísa Saddi , Duarte Carla Oliveira Parra , Pereira Caroline Silva 
Published: October 2018

AbstractBackgroundExcessive sweating is a clinical condition that can be improved with type-A botulinum toxin (BTX-A).ObjectivesTo evaluate and compare the largest diameter of sweating inhibition halo (SIH) of 5 different commercially available BTX-A, in five different doses, in a 6-month-long clinical evaluation.MethodsTwenty-five adult female volunteers were injected in the dorsal trunk area with both 100 units (100UI) and 500 units (500UI) BTX-A products, reconstituted in a ratio of 1:2.5 IU, respectively. Products were applied in five different concentrations (1:2.5U, 2:5U, 3:7.5U, 4:10U, and 5:12.5U). After 30, 60, 90, 120, 150, and 180 days, a starch-iodine test was performed to obtain the largest diameter of each SIH.ResultsThe higher the number of units used, the larger the SIH p < 0.05 for all BTX-A. However, Botox®, Botulift®, Dysport®, and Prosigne® have pretty likewise SIH along the study, with some few differences for some doses and months between one and another. However, Xeomin® is the BTX-A with the smallest SIH, in comparison with all others, in any dose and period.ConclusionsDifferences were observed among all brands of BTX-As, based on dose and time after injection. Xeomin® provides the smallest SIH in comparison with others BTX-A.Level of Evidence: 2