bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cauliflower‐like polypyrrole@MnO2 modified carbon cloth as a capacitive anode for high‐performance microbial fuel cells
Authors: Zhao Xiaohua , Tian Tian , Guo Min , Liu Xin , Liu Xiang 
Published: October 2019

AbstractBACKGROUNDThe morphology and size of MnO2 that deposited on a carbon clothelectrode have dramatic effects on the electrochemical properties and cycling life. Currently, MnO2 and its composite structures with zero‐dimensional (0D) nanospheres, one‐dimension (1D) nanotubes and two‐dimension (2D) nanomesh have been successfully synthesized and employed in MFC. Hence, the development of a three‐dimensional (3D) flexible, cost‐effective and high‐performance anode is of great significance for microbial energy harvesting.RESULTHerein, we have fabricated 3D cauliflower‐like polypyrrole@manganese dioxide (PPy@MnO2) composites, which are successfully grown on carbon cloth (CC) anode by electrodeposition to promote the power production and storage in microbial fuel cells (MFCs). Impressively, the as‐prepared PPy@MnO2 modified CC anode delivers a power density of 2139.7 ± 17.5 mW m−2 and produces an areal capacitance of 1120 ± 12.8 mF cm−2, which is 3.58 and 4.84 folds higher than that with bare CC anode, benefiting from the unique cauliflower‐like 3D architecture with increased active centers that host the bacteria for more efficient charge transfer. Electrochemical analyses indicate that the PPy@MnO2 modified CC electrode has excellent electrochemical activity, capacitive behavior and long‐term cyclabilities with smooth surface morphology and high porosity.CONCLUSIONThese findings not only provide a facile electrodeposition strategy for PPy@MnO2 nanoflowers modified CC anode, but also demonstrates its potential for the production and storage of energy simultaneously in MFC application. © 2019 Society of Chemical Industry
Three‐dimensional echocardiographic comparison of left ventricular geometry and systolic function between dilated cardiomyopathy and mitral regurgitation with similar left ventricular dilation
Authors: Zeng DeCai , Wu Ji , Wu Shui‐Shun , Lin Hai‐Hong , Chen Hui 
Published: October 2019

AbstractPurposeThis study aimed to analyze left ventricular (LV) remodeling in patients with LV dilation using three‐dimensional (3D) echocardiography, and to compare geometry and systolic function between patients with dilated cardiomyopathy (DCM) and with mitral regurgitation (MR) but similar LV dimension.MethodsCross‐sectional study of 60 DCM and 60 MR patients with LV end diastolic diameter (LVEDD) > 35 mm/m2, and of 60 healthy control volunteers.ResultsDespite a similar LVEDD, DCM patients showed a significantly higher 3D sphericity index (3D‐SI) than MR patients, whereas 3D ejection fraction (3D‐EF) was significantly lower (P < .01). There was a linear relationship between 3D‐EF and 3D‐SI in both DCM and MR patients (r = −0. 745 and r = −0. 642, respectively; both P < .001). Receiver operating characteristic (ROC) curves showed that 3D‐SI had could better discriminate between DCM and MR (sensitivity 90%; specificity 73%; AUC 0.852, P < .01) than other variables. The area under the ROC curve of 3D‐SI was significantly larger than that of 3D‐EF for detecting heart failure in both patients with DCM and MR.ConclusionsLV geometry appears to be more spherical and associated with worse systolic function in DCM than in MR patients, in spite of similar LV dimensions. Systolic function correlated significantly with 3D‐SI, which provided a better description of LV remodeling and could be a stronger indicator of heart failure in patients with LV dilation.
The first gap for total curvatures of planar graphs with nonnegative curvature
Authors: Hua Bobo , Su Yanhui 
Published: October 2019

AbstractWe prove that the total curvature of a planar graph with nonnegative combinatorial curvature is at least 1/12 if it is positive. Moreover, we classify the metric structures of ambient polygonal surfaces for planar graphs attaining this bound.
Edge Kempe equivalence of regular graph covers
Authors: Lazarovich Nir , Levit Arie 
Published: October 2019

AbstractLet be a finite ‐regular graph with a proper edge coloring. An edge Kempe switch is a new proper edge coloring of obtained by switching the two colors along some bichromatic cycle. We prove that any other edge coloring can be obtained by performing finitely many edge Kempe switches, provided that is replaced with a suitable finite covering graph. The required covering degree is bounded above by a constant depending only on .
Impact of tumor size and nodal status on recurrence of nonfunctional pancreatic neuroendocrine tumors ≤2 cm after curative resection: A multi‐institutional study of 392 cases
Authors: Dong Ding‐Hui , Zhang Xu‐Feng , Poultsides George , Rocha Flavio , Weber Sharon , Fields Ryan , Idrees Kamran , Cho Cliff , Maithel Shishir K. , Pawlik Timothy M. ,   other members of the US Neuroendocrine Tumor Study Group
Published: October 2019

AbstractBackgroundThe current study sought to define the impact of lymph node metastasis (LNM) relative to tumor size on tumor recurrence after curative resection for nonfunctional pancreatic neuroendocrine tumors (NF‐pNETs) ≤2 cm.MethodsPatients who underwent curative resection for ≤2‐cm NF‐pNETs were identified from a multi‐institutional database. Risk factors associated with tumor recurrence as well as LNM were identified. Recurrence‐free survival (RFS) was compared among patients with or without LNM.ResultsA total of 392 ≤2‐cm NF‐pNETs patients were identified. Among the 328 patients who had lymph node dissection and evaluation, 42 (12.8%) patients had LNM. LNM was associated with tumor recurrence (hazard ratio, 3.06; P = .026) after surgery. RFS was worse among LNM vs no LNM patients (5‐year RFS, 81.7% vs 94.1%; P = .019). Patients with tumors measuring 1.5‐2 cm had a two‐fold increase in the incidence of LNM vs patients with tumors <1.5 cm (17.9% vs 8.7%, odds ratio, 2.59; P = .022), as well as a higher risk of advanced tumor grade and higher Ki‐67 levels (both P < .01). After curative resection, a total of 14 (8.0%) patients with a tumor of 1.5‐2 cm and 10 (4.5%) patients with tumor <1.5 cm developed tumor recurrence.ConclusionSurgical resection with lymphadenectomy should be considered for patients with NF‐pNETs ≥1.5‐2.0 cm.
Imaging diagnosis for intervertebral disc
Authors: Ogon Izaya , Takebayashi Tsuneo , Takashima Hiroyuki , Morita Tomonori , Terashima Yoshinori , Yoshimoto Mitsunori , Yamashita Toshihiko 
Published: October 2019

AbstractVarious functional magnetic resonance imaging (MRI) techniques have been investigated in recent years and are being used in clinical practice for the patients with low back pain (LBP). MRI is an important modality for diagnosing intervertebral disc (IVD) degeneration. In recent years, there have been several reported attempts to use MRI T2 mapping and MRI T1ρ mapping to quantify lumbar disc degeneration. MRI T2 mapping involves digitizing water content, proteoglycan content, and collagen sequence breakdown as relaxation times (T2 values) at each site. These digitized values are used to create a map, that is, then used to quantitatively evaluate the metabolite concentrations within IVD tissues. MRI T2 mapping utilizes the T2 relaxation time to quantify moisture content and the collagen sequence breakdown. MRI T1ρ mapping digitizes water molecule dispersion within the cartilaginous matrix to evaluate the degree of cartilaginous degeneration. Magnetic resonance spectroscopy is a less‐invasive diagnostic test that provides biochemical information. Adequate analysis of the IVD has not yet been performed, although there are indications of a relationship between the adipose content of the multifidus muscle in the low back and LBP. The ultra short TE technique has been recently used to investigate lumbar cartilaginous endplates. Unlike diagnosis based on contrast‐enhanced images of the IVD, which depends on the recurrence of pain that is determined subjectively, MRI‐based diagnosis is less‐invasive and based on objective imaging findings. It is therefore expected to play a key role in the diagnostic imaging of IVD conditions in the future.
Injection of bevacizumab and cyanoacrylate glue for hereditary hemorrhagic telangiectasia
Authors: Khoueir Nadim , Borsik Michel , Camous Domitille , Herman Philippe , Verillaud Benjamin 
Published: October 2019

Objectives/HypothesisThe objective of this study was to report for the first time on the results of submucosal injections of bevacizumab used in conjunction with cyanoacrylate glue sclerotherapy in hereditary hemorrhagic telangiectasia (HHT).Study DesignRetrospective analytic chart review.MethodsWe performed a chart review that included all patients with HHT treated with intranasal bevacizumab and cyanoacrylate glue for refractory epistaxis at Lariboisiere University Hospital from 2013 with a minimum follow‐up of 6 months. We injected 100 mg (25 mg/mL) of bevacizumab diluted in 2 mL of serum at the base of the telangiectasias, and sclerotherapy with an injection of cyanoacrylate glue was used adjunctively. Treatment efficacy was based on changes in Epistaxis Severity Scores (ESS) and the Bergler‐Sadick Scale. Quality of life and patient satisfaction were evaluated using the Cantril Self‐Anchoring Ladder (CL) and Likert scale, respectively.ResultsThirty‐one patients were included, with a mean follow‐up of 26.6 months. The average ESS score significantly decreased from 7.82 to 3.89 (P < .05). The Bergler‐Sadick score significantly improved (P < .05) following the treatment, including the frequency (from 2.74 to 1.64) and the quantity (from 2.54 to 1.51) scales. Quality of life was significantly improved (P < .05) using the CL score (from 4.16 to 7.22). The Likert satisfaction scale related to the treatment efficacy was high, with an average of 7.03 out of 10. No complications were noted.ConclusionsSubmucosal injections of bevacizumab in conjunction with cyanoacrylate glue sclerotherapy significantly reduced epistaxis and improved the quality of life in HHT. Prospective comparative studies are needed to further evaluate the significance of this treatment modality.Level of Evidence3bLaryngoscope, 129:2210–2215, 2019
Laryngeal adductor function following potassium titanyl phosphate laser welding of the recurrent laryngeal nerve
Authors: Bhatt Neel K. , Faddis Brian T. , Paniello Randal C. 
Published: October 2019

Objectives/HypothesisRecurrent laryngeal nerve (RLN) transection injuries may occur during thyroidectomy and other surgical procedures. Laser nerve welding has been shown to cause less technique‐related axonal damage than the traditional suture method. We compared functional adductor results using these two methods of RLN repair.Study DesignAnimal model.MethodsCanine hemilarynges underwent pretreatment testing of laryngeal adductor function, followed by RLN transection and repair using potassium titanyl phosphate (KTP) laser welding (n = 8) or microneural suture (n = 16) techniques. Six months later, adductor function was measured again and expressed as a proportion of the pretreatment value.ResultsThe mean laryngeal adductor pressure ratios were 82.4% (95% confidence interval [CI]: 72.8%‐92.0%) for the laser repair group and 55.5% (95% CI: 49.4%‐61.6%) for the suture control group, with a difference of 26.9% (95% CI: 15.3%‐38.5%). Both spontaneous and stimulated glottic closure was observed in the laser welding and microsuture repair groups.ConclusionsLaser nerve welding resulted in greater strength of adduction than suture repair of an acutely transected RLN. Suture anastomosis may traumatize more axons than the laser. Stronger vocal fold adduction is associated clinically with better protection from aspiration and improved voice outcomes. KTP laser welding should be considered for anastomosis of the RLN and other nerves.Level of EvidenceNALaryngoscope, 130:1764–1769, 2020
Frequency of post‐tonsillectomy hemorrhage relative to time of day
Authors: Kim Sun Joo , Walsh Jonathan , Tunkel David E. , Boss Emily F. , Ryan Marisa , Lee Andrew H. 
Published: October 2019

ObjectivesPostoperative hemorrhage is a serious complication of tonsillectomy, with secondary bleeding rates affecting up to 0.8% to 3% of patients. Although these bleeds are anecdotally perceived as occurring more frequently at night, the occurrence of hemorrhage relative to the time of day has not been investigated. We measured the frequency of post‐tonsillectomy hemorrhage onset relative to the time of day.MethodsWe reviewed electronic medical records of all patients who experienced postprocedural hemorrhage (International Classification of Disease, Ninth Edition [ICD‐9] 998.11, ICD‐10 J95.830 at two hospitals within a tertiary academic health system in a 10‐year period). Patient demographics, time of bleed onset, emergency room [ED] arrival time, and management (operating room vs. observation) were abstracted. Patients without a recorded bleeding time were excluded. Time of bleed onset was categorized as morning (6:01 am–12 pm), afternoon (12:01 pm–6 pm), evening (6:01 pm–12 am), or overnight (12:01 am–6 am). Chi‐square goodness of fit test was used to assess the distribution of hemorrhage timing (P ≤ 0.05).ResultsA total of 7,396 patients underwent tonsillectomy May 2008 through May 2018, among whom 121 (2%) post‐tonsillectomy hemorrhage patients were identified. Among the 104 patients with ED arrival times, 29 (28%) arrived in the morning; 15 (14%) arrived in the afternoon; 40 (38%) arrived in the evening; and 20 (19%) arrived overnight (P = 0.003). Sixty patients (mean age 17.1 years, standard deviation 16.6) had a recorded timing of bleed onset. Bleed onset occurred most commonly overnight (24, 40%), followed by evening (21, 35%), afternoon (11, 18%), and morning (4, 7%) (P = 0.0007).ConclusionIn this cohort, post‐tonsillectomy hemorrhage occurred most frequently between midnight and 6 am. Our findings confirm anecdotal experience and provide data in setting caregiver expectations.Level of Evidence4 Laryngoscope, 130:1823–1827, 2020
Retrieval of Absorption or Scattering Coefficient Spectrum (RASCS) Program: A Tool to Monitor Optical Properties in Real Time
Authors: Quistián‐Vázquez Brenda , Morales‐Cruzado Beatriz , Sarmiento‐Gómez Erick , Pérez‐Gutiérrez Francisco G. 
Published: October 2019

Background and ObjectivesOptical properties characterize light propagation in turbid media, such as tissue. Recovery of optical properties is of great importance in a wide variety of biomedical applications, including both therapeutic treatments and diagnosis. Most of the available methodologies are well established, however, these are not optimized for real‐time measurements.Study Design/Materials and MethodsOptical properties are recovered using the Inverse Adding Doubling program from reflectance measurements measured with an integrating sphere and light in the visible range. A user‐friendly interface was programmed in Visual Studio and the libraries of a particular spectrophotometer were used. To achieve real‐time measurements, a parallel computing routine was implemented, splitting the whole spectra in threads to be computed independently. Several tests using living tissue and inorganic materials were carried out to validate the proposed algorithm.ResultsRecovery of absorption/scattering coefficient spectrum in the visible range with high precision in a couple of seconds was achieved, demonstrating its capabilities for real‐time monitoring in biomedical applications. The absorption coefficient spectrum shows the expected characteristics according to the different melanin and blood concentration of various volunteers, also showing the expected changes during a thermoregulation process.ConclusionsA real‐time monitoring of optical properties algorithm was developed, including parallel computing and a user‐friendly interface. The proposed algorithm would be of help in biomedical applications, where real‐time monitoring optical properties is required. Lasers Surg. Med. © 2019 Wiley Periodicals, Inc.
PVP‐co‐DMAEMA as Novel Polymeric Coating Material for Probiotic Supplements Delivery
Authors: D'Orazio Giuseppe , De Giani Alessandra , Zampolli Jessica , Zeaiter Zahraa , Di Gennaro Patrizia , La Ferla Barbara 
Published: October 2019

AbstractThe paper investigates the use of poly(1‐vinylpyrrolidone‐co‐2‐dimethylaminoethylmetacrilate) (PVP‐co‐DMAEMA) as a novel coating agent in the preparation of alginate‐based microcapsule for the supplement delivery of probiotics. Probiotic Lactobacillus plantarum is used to study the viability of the encapsulated bacterium when exposed to conditions simulating the gastrointestinal tract and industrial process. Results demonstrate that the PVP‐co‐DMAEMA polymer constitutes a pH‐responsive coating suitable for probiotic supplement delivery.
Drivers and outcomes of political candidate image creation: The role of social media marketing
Authors: Hultman Magnus , Ulusoy Sera , Oghazi Pejvak 
Published: October 2019

AbstractThe study examines the role of social media marketing (SMM) activities and the influence of perceived candidate image in building voter–candidate relationship equity within the context of United Kingdom (UK) politics. Drawing from branding literature and social identity theory the article further investigates the role of candidate image as a mediator between SMM and voter–candidate relationship equity, whilst also testing the moderating effect of political ideologies. Survey results from 235 young UK voters indicate that while all SMM activities appears to positively influence the perceived candidate image, not all SMM variables directly relate to relationship equity. The relationship rather appears to be an indirect one, mediated through the political candidate's image. Surprisingly, political ideology also does not appear to moderate the connection between candidate image and voter–candidate relationship equity. The study findings highlight the growing importance of SMM activities and candidate image in political contexts, providing insights for political campaigners.
Dyskinesia‐inducing lead contacts optimize outcome of subthalamic stimulation in Parkinson's disease
Authors: Bouthour Walid , Béreau Matthieu , Kibleur Astrid , Zacharia André , Tomkova Chaoui Emilie , Fleury Vanessa , Benis Damien , Momjian Shahan , Bally Julien , Lüscher Christian , Krack Paul , Burkhard Pierre R. 
Published: October 2019

AbstractBackgroundAcute dyskinesias elicited by STN‐DBS, here referred to as stimulation‐induced dyskinesias, predict optimal clinical outcome in PD. However, it remains elusive whether stimulation‐induced dyskinesias can guide DBS programming.ObjectivesHere, we characterized stimulation‐induced dyskinesias clinically and anatomically. We then tested whether dyskinesia‐inducing contacts could be effectively programmed using independent current source technology.MethodsWe characterized stimulation‐induced dyskinesias with directional and ring stimulation retrospectively in 20 patients. We then localized dyskinesia‐inducing contacts by imaging coregistration and eventually programmed those contacts.ResultsWe elicited dyskinesias in half of our patients. Dyskinesia‐inducing contacts were mainly directional and were all located ventrally within the dorsolateral motor STN. When these dyskinesia‐inducing contacts were programmed using independent current source technology, dyskinesia disappeared and robust antibradykinetic effects were obtained.ConclusionWe confirm that stimulation‐induced dyskinesias are helpful clinical observations, which may guide programming of directional STN‐DBS in PD. © 2019 International Parkinson and Movement Disorder Society
Visual Sensory Processing is Altered in Myoclonus Dystonia
Authors: Tarrano Clément , Wattiez Nicolas , Delorme Cécile , McGovern Eavan M. , Brochard Vanessa , Thobois Stéphane , Tranchant Christine , Grabli David , Degos Bertrand , Corvol Jean‐Christophe , Pedespan Jean‐Michel , Krystkoviak Pierre , Houeto Jean‐Luc , Degardin Adrian , Defebvre Luc , Valabrègue Romain , Vidailhet Marie , Pouget Pierre , Roze Emmanuel , Worbe Yulia 
Published: October 2019

ABSTRACTBackgroundAbnormal sensory processing, including temporal discrimination threshold, has been described in various dystonic syndromes.ObjectiveTo investigate visual sensory processing in DYT‐SGCE and identify its structural correlates.MethodsDYT‐SGCE patients without DBS (DYT‐SGCE‐non‐DBS) and with DBS (DYT‐SGCE‐DBS) were compared to healthy volunteers in three tasks: a temporal discrimination threshold, a movement orientation discrimination, and movement speed discrimination. Response times attributed to accumulation of sensory visual information were computationally modelized, with μ parameter indicating sensory mean growth rate. We also identified the structural correlates of behavioral performance for temporal discrimination threshold.ResultsTwenty‐four DYT‐SGCE‐non‐DBS, 13 DYT‐SGCE‐DBS, and 25 healthy volunteers were included in the study. In DYT‐SGCE‐DBS, the discrimination threshold was higher in the temporal discrimination threshold (P = 0.024), with no difference among the groups in other tasks. The sensory mean growth rate (μ) was lower in DYT‐SGCE in all three tasks (P < 0.01), reflecting a slower rate of sensory accumulation for the visual information in these patients independent of DBS. Structural imaging analysis showed a thicker left primary visual cortex (P = 0.001) in DYT‐SGCE‐non‐DBS compared to healthy volunteers, which also correlated with lower μ in temporal discrimination threshold (P = 0.029). In DYT‐SGCE‐non‐DBS, myoclonus severity also correlated with a lower μ in the temporal discrimination threshold task (P = 0.048) and with thicker V1 on the left (P = 0.022).ConclusionIn DYT‐SGCE, we showed an alteration of the visual sensory processing in the temporal discrimination threshold that correlated with myoclonus severity and structural changes in the primary visual cortex. © 2019 International Parkinson and Movement Disorder Society
Short Versus Conventional Pulse‐Width Deep Brain Stimulation in Parkinson's Disease: A Randomized Crossover Comparison
Authors: Dayal Viswas , Grover Timothy , Tripoliti Elina , Milabo Catherine , Salazar Maricel , Candelario‐McKeown Joseph , Athauda Dilan , Zrinzo Ludvic , Akram Harith , Hariz Marwan , Limousin Patricia , Foltynie Thomas 
Published: October 2019

AbstractBackgroundSubthalamic nucleus deep brain stimulation (STN‐DBS) is an effective therapy for selected Parkinson's disease patients with motor fluctuations, but can adversely affect speech and axial symptoms. The use of short pulse width (PW) has been shown to expand the therapeutic window acutely, but its utility in reducing side effects in chronic STN‐DBS patients has not been evaluated.ObjectiveTo compare the effect of short PW settings using 30‐μs with conventional 60‐μs settings on stimulation‐induced dysarthria in Parkinson's disease patients with previously implanted STN‐DBS systems.MethodsIn this single‐center, double‐blind, randomized crossover trial, we assigned 16 Parkinson's disease patients who had been on STN‐DBS for a mean of 6.5 years and exhibited moderate dysarthria to 30‐μs or 60‐μs settings for 4 weeks followed by the alternative PW setting for a further 4 weeks. The primary outcome was difference in dysarthric speech measured by the Sentence Intelligibility Test between study baseline and the 2 PW conditions. Secondary outcomes included motor, nonmotor, and quality of life measures.ResultsThere was no difference in the Sentence Intelligibility Test scores between baseline and the 2 treatment conditions (P = 0.25). There were also no differences noted in motor, nonmotor, or quality of life scores. The 30‐μs settings were well tolerated, and adverse event rates were similar to those at conventional PW settings. Post hoc analysis indicated that patients with dysarthria and a shorter duration of DBS may be improved by short PW stimulation.ConclusionsShort PW settings using 30 μs did not alter dysarthric speech in chronic STN‐DBS patients. A future study should evaluate whether patients with shorter duration of DBS may be helped by short PW settings. © 2019 International Parkinson and Movement Disorder Society