bluuebunny/crossref_metadata_2025_split huggingface dataset:
China’s impact on pass-through to US import prices
Authors: Malenbaum Michael 
Published: March 2019

Purpose
This paper aims to analyze the marked decline in exchange rate pass-through to US import prices in the early 2000s focusing on the increased role of China as a trade partner. In particular, the research focuses on the impact of an exporter with a fixed exchange rate having large market shares of a particular importing country.

Design/methodology/approach
The study uses highly disaggregated US import data and rolling regressions to calculate quarterly pass-through estimates for specific goods from every exporter. This leads to a total of over 1.7 million pass-through coefficients. The second stage compares these pass-through coefficients with China’s share of US import market for that particular good and time.

Findings
The paper shows that as China’s market share for specific goods grows, pass-through rates of imports from other countries falls. Pass-through rates remain relatively stable for goods that China does not export to the USA or goods for which China’s share of US imports stays constant. This relationship is stronger when the dollar decreases in value, further suggesting that pressure from China forces competitors to maintain stable prices.

Originality/value
This paper is unique in its use of highly disaggregated data on US imports. While many analyses of exchange rate pass-through focus on overall levels or general goods, this work uses import data at the 10-digit HTS code level. Therefore, the findings are more detailed in showing how China’s increased presence in the US market influences prices of imports from other countries.
How do Argentine SMEs define CSR? Cases in educational social development
Authors: Massoud Jacob A. , Daily Bonnie F. , Willi Alberto 
Published: March 2019

Purpose
The purpose of this paper is to investigate the social responsibility approaches of six small and medium-sized enterprises (SMEs) in Argentina and their definitions of corporate social responsibility (CSR).

Design/methodology/approach
This is an exploratory, qualitative study and part of a broader study. A sample of six Argentine SMEs from manufacturing, services and construction sectors was used to evaluate specific CSR initiatives in the areas of social development. A total of 23 interviews were conducted, and open coding was used to analyze and develop categories and themes from the data patterns.

Findings
Results provide a set of definitional dimensions for CSR from an Argentine perspective, and indicate that SMEs in Argentina frequently engage in education and training oriented initiatives as a primary emphasis for their CSR efforts. Commitment, community and employee orientations, the natural environment, and education/training represent key elements of their conceptualizations of CSR.

Originality/value
This research extends the literature related to CSR definitions. It also highlights elements of a growing trend around educational social development initiatives in developing countries. Additionally, it is one of only a few studies to focus on Argentina.
Identification of two clip domain serine proteases involved in the pea aphid's defense against bacterial and fungal infection
Authors: Ma Li , Chen Feng , Wang Wen , Xu Lu , Lu Zhi‐Qiang 
Published: March 2019

AbstractPhenoloxidases (POs) are required for the pea aphid's defense against bacterial and fungal infection. Prophenoloxidases (PPOs) are proteolytically converted to its active form PO through a clip domain serine protease cascade. In this study, we identified five clip domain serine proteases in the pea aphids. The messenger RNA levels of two of them, Ap_SPLP and Ap_VP, were upregulated by Gram‐positive bacterium Staphylococcus aureus and fungus Beauveria bassiana infections. Double‐stranded RNA‐based expression knockdown of these two genes resulted in reduced PO activity of the aphid hemolymph, higher loads of S. aureus and B. bassiana in the aphids, and lower survival rates of the aphids after infections. Our data suggest that Ap_SPLP and Ap_VP are involved in PPO activation pathway in the pea aphid.
Ineffective Airway Clearance in Surgical Patients: Evaluation of Nursing Interventions and Outcomes
Authors: da Silva Lorrany Fontenele Moraes , Pascoal Lívia Maia , Nunes Simony Fabíola Lopes , de Sousa Freire Vanessa Emille Carvalho , de Araújo Almeida Alana Gomes , Gontijo Paula Vitória Costa , Neto Marcelino Santos 
Published: March 2019

PURPOSETo evaluate the benefits of NIC interventions in postoperative patients with ineffective airway clearance (00031).METHODSQuasi‐experimental study with interrupted time‐series design. A total of 101 patients were evaluated during 4 days based on the nursing outcome Respiratory Status: Airway Patency (0410).FINDINGSInterventions such as cough enhancement (3250), ventilation assistance (3390), and airway management (3140) contributed to significative improvements of the patients’ airway patency. Site of surgery and patients’ intrinsic characteristics were proven to have influence in the NOC ratings.CONCLUSIONSInterventions implemented during the research contributed to improvement of clinical indicators of airway patency.IMPLICATIONS FOR NURSING PRACTICEPostoperative respiratory complications can be minimized by the use of standardized nursing languages.
Fasudil alleviates brain damage in rats after carbon monoxide poisoning through regulating neurite outgrowth inhibitor/oligodendrocytemyelin glycoprotein signalling pathway
Authors: Wang Li , Xu Jianghua , Guo Dadong , Zhou Xudong , Jiang Wenwen , Wang Jinglin , Tang Jiyou , Zou Yong , Bi Mingjun , Li Qin 
Published: March 2019

AbstractCarbon monoxide (CO) poisoning can lead to many serious neurological symptoms. Currently, there are no effective therapies for CO poisoning. In this study, rats exposed to CO received hyperbaric oxygen therapy, and those in the Fasudil group were given additional Fasudil injection once daily. We found that the escape latency in CO poisoning group (CO group) was significantly prolonged, the T1/Ttotal was obviously decreased, and the mean escape time and the active escape latency were notably extended compared with those in normal control group (NC group, P < 0.05). After administration of Fasudil, the escape latency was significantly shortened, T1/Ttotal was gradually increased as compared with CO group (>1 week, P < 0.05). Ultrastructural damage of neurons and blood‐brain barrier of rats was serious in CO group, while the structural and functional integrity of neuron and mitochondria maintained relatively well in Fasudil group. Moreover, we also noted that the expressions of neurite outgrowth inhibitor (Nogo), oligodendrocyte‐myelin glycoprotein (OMgp) and Rock in brain tissue were significantly increased in CO group, and the elevated levels of the three proteins were still observed at 2 months after CO poisoning. Fasudil markedly reduced their expressions compared with those of CO group (P < 0.05). In summary, the activation of Nogo‐OMgp/Rho signalling pathway is associated with brain injury in rats with CO poisoning. Fasudil can efficiently down‐regulate the expressions of Nogo, OMgp and Rock proteins, paving a way for the treatment of acute brain damage after CO poisoning.
G‐CSF administration prior to donor lymphocyte apheresis promotes anti‐leukaemic effects in allogeneic HCT patients
Authors: Schneidawind Corina , Jahnke Simona , Schober‐Melms Irmtraud , Schumm Michael , Handgretinger Rupert , Faul Christoph , Kanz Lothar , Bethge Wolfgang , Schneidawind Dominik 
Published: March 2019

SummaryDonor lymphocyte infusion (DLI) is an effective method to establish full donor chimerism or to prevent and treat relapse after allogeneic haematopoietic cell transplantation (allo‐HCT). Usually, DLIs are collected from naïve donors as steady‐state lymphocytes. When donor lymphocytes are collected during stem cell apheresis, donors are pre‐treated with granulocyte colony‐stimulating factor (G‐CSF). However, the impact of G‐CSF stimulation and the resulting composition of DLIs on beneficial anti‐leukaemic responses and survival remain elusive. Therefore, we performed a retrospective analysis to evaluate the role of G‐CSF‐DLIs: 44 patients received either steady‐state DLIs or G‐CSF‐DLIs to prevent and treat relapse or establish full donor chimerism after allo‐HCT. The G‐CSF‐DLI patient cohort showed an improved conversion to full donor chimerism and a lower cumulative incidence of relapse or disease progression without a significantly increased cumulative incidence of graft‐versus‐host disease (GVHD). CD34+ cells, monocytic myeloid‐derived suppressor cells and monocytes as well as donor age and the subsequent occurrence of chronic GVHD were identified as risk factors that significantly improve overall survival after DLI administration. In conclusion, our data suggest that administration of G‐CSF‐DLIs results in graft‐versus‐leukaemia effects without exacerbating GVHD, therefore, improving survival after DLIs.
Atypical haemolytic uraemic syndrome in the eculizumab era: presentation, response to treatment and evaluation of an eculizumab withdrawal strategy
Authors: Neave Lucy , Gale Daniel P. , Cheesman Simon , Shah Raakhee , Scully Marie 
Published: March 2019

SummaryThe complement inhibitor, eculizumab, has revolutionised the management of atypical haemolytic uraemic syndrome (aHUS), although the optimum treatment duration is debated. Twenty‐two cases of acute aHUS managed with eculizumab were retrospectively reviewed, including outcomes after eculizumab withdrawal. Although 41% had an associated complement genetic abnormality, mutation status did not affect severity of clinical presentation. Sixty‐four percent required renal replacement acutely, with a high incidence of nephrotic range proteinuria (47%). Eculizumab followed a median of 6 days of plasma exchange. After a median duration of therapy of 11 weeks (range 1–227), haematological recovery was seen in 100%, while 81% achieved at least partial renal recovery (median increase in estimated glomerular filtration rate (eGFR) 49 ml/min/1·73 m2). At median duration of follow‐up of 85 weeks (range 4–255), 54·5% had eGFR ≥ 60 ml/min/1·73 m2, 27% had CKD, 14% were on dialysis, and 4·5% had died. Eculizumab was withdrawn in 59% (13/22) cases following complete haematological and renal recovery. Three of these 13 patients (23%) subsequently relapsed, with defined triggers in 2/3, but all made a full recovery with rapid resumption of eculizumab. There was a significant association between higher presenting creatinine and poorer renal outcomes. A strategy of eculizumab withdrawal in selected cases is both safe and cost effective.
Culture‐based methods using low‐temperature incubation revealed cold‐adapted fungal endophytes from semiarid forests
Authors: Hagh Doust Niloufar , Safaie Naser , Schmitt Imke , Otte Juergen , Bálint Miklós 
Published: March 2019

AbstractFungal endophytes are an important part of the plant microbiome and participate in maintaining the stability of ecosystems. Culture‐based methods are frequently considered in studying fungal communities because of their advantages in providing cultures for further experiments and their low cost. In comparison with next‐generation sequencing methods, their ability to assess fungal diversity is questionable. Here, we show how using two different incubation temperatures can improve the yield of fungal endophytes by culture‐based methods. Diversity, organ preference and spatiotemporal variability of endophytic fungal communities living within Quercus brantii L. were investigated using two different incubation temperatures. To test the effects of using low‐temperature incubation on diversity estimations, twigs and leaves of Quercus brantii were incubated under 25°C and 4°C conditions. Isolation rate and Hill's series of diversity were calculated for each sample. Model‐based analysis was used to evaluate the effects of (a) incubation temperature, (b) organ type and (c) spatiotemporal variations on fungal isolation rate, fungal diversity and community composition. Our results showed a strong organ specificity and temporal dynamics among endophytic fungal communities, but the location of the forest stand had only a limited effect on fungal community composition. Low‐temperature incubation enabled us to improve culture‐based methods by discovering the diversity of cold‐adapted fungal endophytes and a significantly different part of the endophytic communities that is usually missed by customary culturing temperature. The isolation of cold‐adapted endophytes from a semiarid environment opens a new window to further studies on this kind of fungi in such ecosystems.
Silencing of carbonic anhydrase I enhances the malignant potential of exosomes secreted by prostatic tumour cells
Authors: Bánová Vulić Radivojka , Zdurienčíková Martina , Tyčiaková Silvia , Benada Oldřich , Dubrovčáková Mária , Lakota Ján , Škultéty Ľudovít 
Published: March 2019

AbstractWe report results showing that the silencing of carbonic anhydrase I (siCA1) in prostatic (PC3) tumour cells has a significant impact on exosome formation. An increased diameter, concentration and diversity of the produced exosomes were noticed as a consequence of this knock‐down. The protein composition of the exosomes' cargo was also altered. Liquid chromatography and mass spectrometry analyses identified 42 proteins significantly altered in PC3 siCA1 exosomes compared with controls. The affected proteins are mainly involved in metabolic processes, biogenesis, cell component organization and defense/immunity. Interestingly, almost all of them have been described as ‘enhancers' of tumour development through the promotion of cell proliferation, migration and invasion. Thus, our results indicate that the reduced expression of the CA1 protein enhances the malignant potential of PC3 cells.
Central role of the LEAFY COTYLEDON1 transcription factor in seed development
Authors: Jo Leonardo , Pelletier Julie M. , Harada John J. 
Published: March 2019

AbstractSeed development is a complex period of the flowering plant life cycle. After fertilization, the three main regions of the seed, embryo, endosperm and seed coat, undergo a series of developmental processes that result in the production of a mature seed that is developmentally arrested, desiccated, and metabolically quiescent. These processes are highly coordinated, both temporally and spatially, to ensure the proper growth and development of the seed. The transcription factor, LEAFY COTYLEDON1 (LEC1), is a central regulator that controls several aspects of embryo and endosperm development, including embryo morphogenesis, photosynthesis, and storage reserve accumulation. Thus, LEC1 regulates distinct sets of genes at different stages of seed development. Despite its critical importance for seed development, an understanding of the mechanisms underlying LEC1's multifunctionality is only beginning to be obtained. Recent studies describe the roles of specific transcription factors and the hormones, gibberellic acid and abscisic acid, in controlling the activity and transcriptional specificity of LEC1 across seed development. Moreover, studies indicate that LEC1 acts as a pioneer transcription factor to promote epigenetic reprogramming during embryogenesis. In this review, we discuss the mechanisms that enable LEC1 to serve as a central regulator of seed development.
Intragroup competition in public good games: The role of relative performance incentives and risk attitudes
Authors: Colasante Annarita , García‐Gallego Aurora , Georgantzis Nikolaos , Morone Andrea , Temerario Tiziana 
Published: March 2019

AbstractWe analyze a public good game (PGG) with intragroup competition in which, generally but not always, the dominant strategy is to not contribute; therefore, free riding is the unique Nash equilibrium, not achieving Pareto efficiency. We propose a PGG setup where subjects' contributions are rewarded with different individual returns following a rank‐order voluntary contribution mechanism. It is found that the resulting competition for a better return significantly increases contributions. This effect is sensitive to the salience of return differences rewarding higher contributions. Furthermore, the positive effect of return differences on contribution levels depends on an individual's return‐to‐risk sensitivity as elicited through an independent risk elicitation task.
Optional and alternating case marking: Typology and diachrony
Authors: Chappell Hilary , Verstraete Jean‐Christophe 
Published: March 2019

AbstractThis paper presents a survey of the typology and diachrony of optional and alternating case marking, in the context of related phenomena such as referent‐ and construction‐based splits. While there is much recent work in this area, driven by text‐based approaches to language description, as well as quantitative and areal approaches to typology, the domain remains somewhat scattered, conceptually and terminologically. We chart the relevant phenomena, and we provide a typological survey of optional and alternating marking for A and O arguments. We also highlight some of the questions that remain, including problems with the classic model of case marking based on markedness reversal. A final section investigates the diachronic origins of optional case markers. These are largely similar to those for non‐optional systems, apart from certain source domains, as well as factors related to information structure, both in the form of source domains and as constructional contexts playing a role in the development of the markers.
Mobile Work, Veterinary Subjectivity and Brexit: Veterinary Surgeons’ Migration to the UK
Authors: Enticott Gareth 
Published: March 2019

AbstractThis article extends studies of ‘global work’ by considering the mobility of veterinary surgeons in the global countryside. The article develops the concept of ‘disease ecology’: an assemblage of heterogenous actors and relations that inscribe and normalise mobility within professional subjectivities. Disruptions to these disease ecologies can contribute to new patterns of mobility. Drawing on biographical narrative interviews with 35 vets who have migrated to the United Kingdom to work, the article shows how veterinary mobility is shaped by and emerges in response to these disease ecologies. Specifically, the article describes how four narratives – ‘the first job’, ‘escape and adventure’, ‘the lucky break’ and ‘staying mobilities’ – contribute to veterinary migration to the UK, and how the lived experiences of work and inscriptions of mobile veterinary subjectivities within disease ecologies lead vets to stay in the UK. However, the article also considers the role of Brexit in disrupting established disease ecologies and creating new patterns of veterinary mobilities. In identifying how Brexit challenges vets’ sense of place, the article concludes by exploring Brexit's potential impact to the future of veterinary services in the UK.
Reviewer Acknowledgements
Authors: Willianms Ellery 
Published: March 2019

Reviewer AcknowledgementsBusiness and Management Studies (BMS) would like to acknowledge the following reviewers for their assistance with peer review of manuscripts for this issue. Many authors, regardless of whether BMS publishes their work, appreciate the helpful feedback provided by the reviewers. Their comments and suggestions were of great help to the authors in improving the quality of their papers. Each of the reviewers listed below returned at least one review for this issue.Reviewers for Volume 5, Number 1 Andrzej Niemiec, Poznań University of Economics and Business, PolandAshford Chea, Benedict College, USAAthina Qendro, Robert Gordon University, UKBahram Abediniangerabi, University of Texas, USAFábio Albergaria de Queiroz, Catholic University of Brasília, BrazilFlorin Peci, University of Peja, KosovoFouad Jawab, Universite Sidi Mohamed Ben, MoroccoFuLi Zhou, Zhengzhou University of Light Industry, ChinaGabriela O. Chiciudean, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, RomaniaHung-Che Wu, Nanfang College of Sun Yat-sen University, ChinaIulia Cristina Muresan, University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca, RomaniaJason Caudill, King University, USAJulia Stefanova, Bulgarian Academy of Sciences, BulgariaKonstantinos N. Malagas, University of the Aegean, GreeceLucie Andreisová, University of Economics in Prague, CzechMarica Ion Dumitrasco, Academy of Sciences of Moldova, MoldovaMichael Okoche, University of South Africa, UgandaMr. Abdul-Kahar Adam, University of Education, Winneba, GhanaMythili Kolluru, College of Banking and Financial Studies, OmanOksana Seroka-Stolka, Technical University of Czestochowa, PolandOzgur Demirtas, Inonu University, TurkeyRaimundo Lima Filho, University of State of Bahia, BrazilRashedul Hasan, International Islamic University Malaysia, MalaysiaRegina Lenart-Gansiniec, Jagiellonian University, PolandRocsana Tonis, Spiru Haret University, RomaniaSammy Kimunguyi, Office of The Auditor-General, KenyaXhavit Islami, University of Prishtina, KosovoYang Zhao, Sanofi Genzyme, USAZeki Atıl Bulut, Dokuz Eylul University, TurkeyZoran Mastilo, University of East Sarajevo, Bosnia and Herzegovina Ellery WillianmsEditorial AssistantOn behalf of,The Editorial Board of Business and Management StudiesRedfame Publishing9450 SW Gemini Dr. #99416Beaverton, OR 97008, USAURL: http://bms.redfame.com
Protocol for a conversation-based analysis study: PREVENT-ED investigates dialogue features that may help predict dementia onset in later life
Authors: de la Fuente Garcia Sofia , Ritchie Craig W , Luz Saturnino 
Published: March 2019

IntroductionDecreasing the incidence of Alzheimer’s disease (AD) is a global public health priority. Early detection of AD is an important requisite for the implementation of prevention strategies towards this goal. While it is plausible that patients at the early stages of AD may exhibit subtle behavioural signs of neurodegeneration, neuropsychological testing seems unable to detect these signs in preclinical AD. Recent studies indicate that spontaneous speech data, which can be collected frequently and naturally, provide good predictors for AD detection in cohorts with a clinical diagnosis. The potential of models based on such data for detecting preclinical AD remains unknown.Methods and analysisThe PREVENT-Elicitation of Dialogues (PREVENT-ED) study builds on the PREVENT Dementia project to investigate whether early behavioural signs of AD may be detected through dialogue interaction. Participants recruited through PREVENT, aged 40–59 at baseline, will be included in this study. We will use speech processing and machine learning methods to assess how well speech and visuospatial markers agree with neuropsychological, biomarker, clinical, lifestyle and genetic data from the PREVENT cohort.Ethics and disseminationThere are no expected risks or burdens to participants. The procedures are not invasive and do not raise significant ethical issues. We only approach healthy consenting adults and all participants will be informed that this is an exploratory study and therefore has no diagnostic aim. Confidentiality aspects such as data encryption and storage comply with the General Data Protection Regulation and with the requirements from sponsoring bodies and ethical committees. This study has been granted ethical approval by the London-Surrey Research Ethics Committee (REC reference No: 18/LO/0860), and by Caldicott and Information Governance (reference No: CRD18048). PREVENT-ED results will be published in peer-reviewed journals.