bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnosis of Autism Spectrum Disorder in Adolescents with Complex Clinical Presentations: A Montreal Case Series
Authors: Garel Nicolas , Garel Patricia 
Published: December 2018

Background:
Despite increased attention and recognition of autism spectrum
disorders, many patients suffering from these disorders remain undiagnosed or are diagnosed
late due to their subtle clinical presentation. The challenge for clinicians working in the field
of mental health is not in screening and diagnosing young children showing typical signs of
autism spectrum disorders, but rather in identifying patients at the high-functioning end of
the spectrum whose intellectual abilities mask their social deficits.

Objective:
Because therapeutic interventions differ radically once the diagnosis of ASD has
been made, it is important to understand the trajectory of those adolescents and identify clues
that could help raise the diagnosis of ASD earlier.

Methods:
Records of eight adolescents with a late diagnosis of ASD were retrospectively
reviewed to identify relevant clinical features that were overlooked in childhood and early
adolescence.

Results:
The patients were previously misdiagnosed with multiple mental health disorders.
These cases showed striking similarities in terms of developmental history, reasons for
misdiagnosis, and the clinical picture at the time of ASD recognition. The cases were
characterized by complex and fluctuating symptomatology, including depression, anxiety,
behavioural problems, self-injurious behaviour and suicidal thoughts. Their Autism
Spectrum Disorder (ASD) went previously undiagnosed due to the individual’s intelligence
and learning abilities, which masked their social deficits and developmental irregularities.
Signs of ASD were continuously present since childhood in all the eight cases. Once the
developmental histories and the psychiatric evaluation of these adolescents were done by
psychiatrists with appropriate knowledge of autism, the diagnosis of ASD was made.

Conclusion:
The ASD hypothesis should be raised in the presence of confusing symptoms
that do not respond to usual treatment and are accompanied by an irregular developmental
background. It is indeed a difficult diagnosis to make; however, the focused clinician can
note subtle signs of ASD despite the intellectual learning of social codes. Family history,
developmental irregularities, rigidity, difficulty in spontaneously understanding emotions,
discomfort in groups and the need to be alone are significant indicators to recognize. Once
the diagnosis has been considered, it must be confirmed or rejected by an experienced
multidisciplinary team. The challenge for clinicians working in the field of mental health is
not in screening and diagnosing young children showing typical signs of ASD, but rather in
identifying patients who are at high-functioning end of the spectrum whose intellectual
abilities mask their social deficits.
Identification of Expressed miRNAs in Human Rheumatoid Arthritis Using Computational Approach – Discovery of a New miR-7167 from Human
Authors: Raj Christian Simon Durai , Thirugnanasambantham Krishnaraj , Islam Mohamed Ibrahim Hairul , Sudalaimuthu Mathan Kumar , Sundaram Sandhya , Ashok Ganapathy , Senthilkumar Venugopal , Muralidaran Senguttuvan , Subramanian Saravanan 
Published: December 2018

Background:
Rheumatoid Arthritis (RA) is a chronic inflammatory and autoimmune disease
leading to bones and joints destruction. It is one of the major causes of lifetime disability and
mortality among humans in the developing and developed countries. It was evident that epigenetic
dysregulation is related to the pathogenesis of RA. MicroRNAs (miRNAs) are small non-coding
RNAs that are epigenetic regulators for diverse biological processes and also provided novel molecular
insights in the formation of arthritis.

Objective:
The influences of miRNAs in the alteration of gene regulation during the pathogenesis of
arthritis were exposed in recent years.

Method:
The computational approach to identify miRNA through EST-based homology is more
powerful, economical and time-efficient. In this study, we applied EST-based homology search to
identify miRNAs responsible for the development of arthritis in human beings.

Results:
Our study on 36519 ESTs in human RA condition revealed the expression of four miRNAs,
HSA-miR-198, HSA-miR-4647, has-miR-7167-5p and has-miR-7167-3p. The present study is the
first report about has-miR-7167 that was homologous to Macaca mulatta.

Conclusion:
The predicted targets of these identified miRNAs revealed many biological functions in
the pathogenesis of RA. Further elaborated studies on these miRNAs will help to understand their
function in the development of RA and the use of miRNAs as therapeutic targets in the future.
Ajuste y selección de modelos matemáticos para predecir el volumen total fustal de Tectona grandis en Nuevo Urecho, Michoacán, México
Authors: Telles Antonio Ricardo , Gómez Cárdenas Martín , Alanís Rodríguez Eduardo , Aguirre Calderón Oscar Alberto , Jiménez Pérez Javier 
Published: December 2018

El objetivo fue ajustar y seleccionar un modelo matemático para predecir volumen total del fuste para una El objetivo fue ajustar y seleccionar un modelo matemático para predecir el volumen fustal de Tectona grandis L. f. en una plantación de 11 años de edad en Nuevo Urecho, Michoacán. La muestra analizada fue de 128 árboles, a los que se les midió el diámetro de tocón, diámetro normal y el diámetro a distintas secciones, desde la altura de tocón hasta altura total. Se ajustaron seis modelos de volumen fustal mediante el procedimiento Model del paquete estadístico SAS 9.2®. La selección del modelo se hizo a partir de la suma de cuadrados del error (SCE), la raíz del error medio cuadrático (REMC) y R2adj además de la significancia de sus parámetros. Se verificó el cumplimiento de los supuestos de normalidad, homogeneidad de varianzas e independencia de la frecuencia de residuos. Se generó un criterio de calificación que jerarquizó cada estadístico en función al orden de importancia, siendo mejores aquellos con el valor más bajo en la calificación total. El modelo de Meyer fue el de mejor ajuste con SCE= 0.0399, REMC= 0.0179 y R2adj= 0.8246. La prueba de Shapiro-Wilk (0.97), White´s Test (13.00) y la de Durbin-Watson (2.0112) no violan los supuestos de la regresión y garantizan la eficacia del modelo para la estimación de la variable dependiente. Este modelo se considera apropiado para predecir con mayor precisión el volumen fustal en función del diámetro normal (d) y la altura total (AT) de T. grandis en plantaciones con condiciones físicas y biológicas similares a las del sitio de este estudio.
Manajemen pendidikan dalam membentuk karakter siswa SMP Tunas Bangsa Sunter
Authors: Julistiaty J. , Madhakomala R. , Matin M. 
Published: December 2018

Penelitian ini dilaksanakan di SMP Tunas Bangsa Sunter Jakarta Utara. Adapun tujuan dari penelitian ini adalah memperoleh pemahaman mendalam Manajemen Pendidikan Karakter SMP Tunas Bangsa. Data yang dikumpulkan dari responden melalui wawancara, observasi dan studi dokumentasi. Teknik keabsahan data menggunakan triangulasi sumber, teori dan waktu. Teknik analisa data yang digunakan dalam penelitian ini adalah reduksi data dan display data. Hasil temuan penelitian meliputi: (1) Perencanaan Pendidikan Karakter di Sekolah Tunas Bangsa, yang selaras dengan visi dan misi, dengan berfokus kepada karakter ketaatan dan penuh perhatian, Kepala sekolah dan timnya membuat program sekolah berbasis karakter; (2) Pelaksanaan Program Pendidikan Karakter, semua program sekolah tersebut disosialisasikan melalui staff meeting, pekan informasi pembelajaran dengan orang tua siswa dan seluruh siswa di awal tahuan pembelajaran; 3) Pengawasan pelaksanaan Program Pendidikan Karakter, untuk memastikan semua kegiatan sekolah berjalan sesuai dengan perencanaan, visi, misi yang ada. Kepala sekolah harus memastikan dengan observasi kepada siswa dan guru dengan standard performa. Temuan mengarah pada rekomendasi untuk menerapkan pendidikan karakter dapat membentuk siswa untuk memiliki kepemimpinan, kemandirian, perilaku yang baik, tanggung jawab sendiri, rasa yang baik di masyarakat, kreatif dan inovatif, ini semua termasuk kepala sekolah, guru dan juga orang tua untuk terlibat agar dapat terlaksana dan tujuan tercapai.Kata kunci: perencanaan, pelaksanaan, pengawasan EDUCATION MANAGEMENT IN FORMING STUDENT CHARACTER OF SMP TUNAS BANGSA SUNTERAbstractThis research was carried out at SMP Tunas Bangsa Sunter, North Jakarta. The purpose of this study was to obtain an in-depth understanding of the Tunas Bangsa Middle School Character Management. Data collected from respondents through interviews, observation and documentation studies.The data were collected through participant observation using interview, observation, document study and recording. The data analysis and interpretation indicates that: 1)Planning of Character Education in Tunas Bangsa School based on vision and mission, focusing in Attentive and obedience character, the headmaster and team made school programs based on character. 2) Actuating of Character Education, all school programs have to socialized through Staff Meeting, Information Day with parents and of course to all students in the new semester. 3) Controlling of Character Education to improve that all school activities would done according to planning, vision and mission. Headmaster has to ensure by observe teachers, students with standard of performance. The finding lead to the recommendation to apply character education could formed students to have leadership, independence, good behavior, self responsible, good sense in community, creative and innovative, these all includes headmaster, teachers and also parents to contribute their effort to make it happen.Keywords: planning, actuating, controlling
Pengaruh model pembelajaran inkuiri terhadap keterampilan berpikir kritis dan hasil belajar peserta didik dalam pembelajaran PPKn
Authors: Sulianti Ani , Murdinono Mukhamad 
Published: December 2018

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran inkuiri terhadap: (1) keterampilan berpikir kritis dan (2) hasil belajar peserta didik dalam pembelajaran Pendidikan Pancasila dan Kewarganegaraan di SMA Negeri 3 Lumajang. Penelitian ini merupakan penelitian quasi experiment. Instrumen yang digunakan adalah observasi dan tes. Data dianalisis dengan menggunakan uji-t. Hasil penelitian, adalah sebagai berikut: (1) Terdapat pengaruh yang signifikan model pembelajaran inkuiri terhadap keterampilan berpikir kritis peserta didik dalam pembelajaran Pendidikan Pancasila dan Kewarganegaraan di SMA Negeri 3 Lumajang pada Kompetensi Dasar menganalisis indikator ancaman terhadap negara dalam membangun integrasi nasional dengan Bhineka Tunggal Ika. (2) Terdapat pengaruh yang signifikan model pembelajaran inkuiri terhadap hasil belajar peserta didik dalam pembelajaran Pendidikan Pancasila dan Kewarganegaraan di SMA Negeri 3 Lumajang pada Kompetensi Dasar menganalisis indikator ancaman terhadap negara dalam membangun integrasi nasional dengan Bhineka Tunggal Ika.Kata kunci: inkuiri, keterampilan berpikir kritis, hasil belajar. THE INFLUENCE OF INQUIRY LEARNING MODEL ON CRITICAL THINKING SKILLS AND STUDENT LEARNING OUTCOMES IN PPKn LEARNINGAbstractThis research aims to determine the effect of inquiry model on: (1) critical thinking skills and (2) learning outcomes in learning civic education of thr students of SMA Negeri 3 Lumajang. This research is a quasi experiment. The data were collected through observation and test.the data were analyzed by using the t-test. The result of this research are as follows. (1) There is a significant effect of inquiry model in critical thinking skill in learning civic education of the students of SMA Negeri 3 Lumajang on the basic competence “analyze indicators of threats to the country in building national integration with unity in diversity”. (2) There is a significant effect of inquiry model on the learning outcomes in learning civic education of the students of SMA Negeri 3 Lumajang on basic the competence “analyze indicators of threats to the country in building national integration with unity in diversity”.Keywords: inquiry, critical thinking skills, outcomes
Pengaruh media pembelajaran terhadap hasil belajar ekonomi ditinjau dari gaya belajar siswa SMA Negeri
Authors: Nurwidayanti Dewi , Mukminan Mukminan 
Published: December 2018

Penelitian ini bertujuan untuk mengetahui perbedaan hasil belajar ekonomi pada siswa yang menggunakan media pembelajaran power point dengan media konvensional pada kelompok siswa dengan gaya belajar visual dan gaya belajar auditorial. Penelitian ini merupakan penelitian eksperimen dengan desain faktorial 2 x 2, menggunakan tes awal (pretest) dan tes akhir (posttest). Penelitian dilakukan di SMAN 4 Yogyakarta dan SMAN 9 Yogyakarta. Populasi penelitian adalah seluruh siswa kelas X SMA Negeri 4 dan SMA Negeri 9 Yogyakarta. Sampel penelitian sebanyak 83 siswa yang diambil dengan teknik simple random sampling. Teknik analisis data menggunakan analisis deskriptif dan uji beda anova dua jalur. Hasil penelitian menunjukkan: Terdapat perbedaan hasil belajar siswa yang pembelajarannya menggunakan media power point dan media konvensional dimana rerata hasil belajar dengan media power point lebih tinggi dibanding menggunakan media konvensional baik itu pada kelompok gaya belajar visual dan kelompok gaya belajar auditorial. Terdapat interaksi antara media pembelajaran dan gaya belajar dalam mempengaruhi hasil belajar Ekonomi.Kata kunci: media pembelajaran, gaya belajar, hasil belajar ekonomi THE EFFECT OF INSTRUCTIONAL MEDIA TOWARD ECONOMIC LEARNING OUTCOMES JUDGING FROM LEARNING STYLES OF SENIOR HIGH SCHOOLAbstractThis study aims to determine differences in economic learning outcomes in students using learning media power point with conventional media in visual style student groups and students auditory style. This research is an experimental research with 2 x 2 factorial design, using pretest and final test (posttest). The research was conducted at SMAN 4 Yogyakarta and SMAN 9 Yogyakarta. The population is all students of class X SMAN 4 Yogyakarta and SMAN 9 Yogyakarta. The sample of research is 83 students taken with simple random sampling technique. The technique of data analysis using descriptive analysis and difference test of two-way ANOVA. The results showed: There are differences in learning outcomes of students who learn by using power point media and using conventional media where the average of learning outcomes with power point media was higher than using conventional media in the visual learning style group and the learning style group. There is a significant interaction between learning media and learning style in influencing the learning result of Economics.Keywords: instructional media, learning style, learning outcomes
Correlation of Limb Bioimpedance to Echocardiographic Indicators of Congestion in Patients with NYHA Class II/III Heart Failure (Preprint)
Authors: Accardi Andrew , Heywood Thomas , Daleiden-Burns Anne 
Published: December 2018

BACKGROUND

The treatment of heart failure (HF) in the United States is estimated to exceed $30 billion each year and is anticipated to increase to a staggering $70 billion by the year 2030. This makes the management of HF one of the leading challenges Medicare will face in the years to come. Traditional methods to detect impending congestion such as body weight and physical examination findings are often non-specific and lack sensitivity making them inadequate to recognize fluid overload and prevent decompensation. It has been suggested that bioimpedance spectroscopy (BIS) can be used as a surrogate marker for detecting fluid overload and therefore, serve as an adjunct to clinical exam findings.

OBJECTIVE

This study examines the relationship between a BIS device and echocardiographic parameters associated with volume overload with same day measurements in the first 8 patients with NYHA Class II/III HF on an IRB approved protocol.

METHODS

Each patient was followed 3 times a week for 4 weeks within the hospital outpatient setting. At each visit BIS measures were recorded for whole body as well as arms and legs. Additionally, signs and symptoms, weight and echocardiograph findings were all recorded.

RESULTS

Correlations of BIS measurements with echo parameters were performed. The leg impedance measurement correlated strongly with echo findings; inferior vena cava (IVC) size (p=0.001), right atrial pressure (RAP) (p<0.001), and pulmonary artery systolic pressure (PAS) measurements (p<0.001).

CONCLUSIONS

Preliminary findings demonstrated excellent correlations with BIS measurements and IVC size, right atrial pressure and pulmonary artery systolic pressure measurements which suggest a possible alternative method to detect fluid overload despite the small sample size. Trending a patient's impedance using the SOZO device at home or the practitioner's office may assist clinicians in providing more accurate, individualized HF care.

CLINICALTRIAL

. IRB approval was obtained for this study (Scripps IRB #IRB-16-6852).
Analisis kepuasan pemustaka terhadap kualitas layanan perpustakaan di perguruan tinggi vokasi dengan metode servqual dan importance-performace analysis
Authors: Rachmadita Renanda Nia , Arninputranto Wibowo 
Published: December 2018

Introduction. Library in Vocational Higher Education is required to provide the best services in facilities, learning environmentbased on the characteristics of vocational education. This study aims to measure the level of satisfaction of library services in vocational colleges. Data Collection Method. The questionnaires were distributed to 150 respondents including students and lecturersbased on five dimensions of Servqual. Data Analysis. The analysis was conducted by identifying the gap between perception and expectation using Importance-Performance Analysis method. Results and Discussions. Overall, the analysis if the gap for all Servqual dimensions was negative. Some services needto be improved to meet user expectations. By using Importance-Performance Analysis, itwas found that the attribute P10 (Library needs to provide an adequate online catalog) should be prioritized..Conclusions. It is expected that the library can improve the services based on the users’ needs.
Makna profesi pustakawan: studi fenomenologi tentang profesi pustakawan lulusan diklat calon pustakawan tingkat ahli (CPTA)
Authors: Oktaviani Niar Eka , Yanto Andri , Rachmawati Tine Silvana 
Published: December 2018

Introduction. Librarians build their librarianship concept based on self understanding of interpretation of the reality from their professional activities in the workplace. This research is very important as the study of a concept of librarian profession from CPTA is limited in Indonesia. Data Collection Method. The research method used is qualitative with phenomenology approach. Five librarians participated in the IPDN Library. Results and Discussions. The results show the three meanings of librarian were as a valuable profession, as a promising profession and as an information service provider. The self-concept found in this study has been seen from three aspects: psychological aspects include a sense of confusion, a sense of comfort, a sense of pride and professional. Further, the social aspects involve being underestimated, harmonious relationships, respecting each other, creating intense competition and having good relationship. Physical aspects include being clean and neat, smart, versatile, attractive as a modern librarian. The motivation to become a librarian is salary and other incomes, competition, and opportunity to improve. Conclusions. The paper shows that librarians interpret themselves as a profession that has a value from the material perspective because it has benefits and allowances related to their work performance. Further research is needed to study a comparison between librarians formal education and librarians from CPTA related to their motivation.
Faculty Development to Promote Effective Instructional Technology Integration: A Qualitative Examination of Reflections in an Online Community
Authors: Sullivan Roberta (Robin) , Neu Victoria , Yang Fengrong 
Published: December 2018

The State University of New York Tools of Engagement Project (TOEP) < http://suny.edu/toep > is an online professional development model that encourages faculty and instructional support staff to explore and reflect on innovative and creative uses of emerging technologies through hands-on Discovery Learning Activities. TOEP is focused on creating peer-learning communities by providing a venue to experiment with the evolving landscape of social media and the latest web-based technology tools. The concept of lifelong learning and how it relates to technology change serves as a guiding principle of this project. This research examines the reflective summary posts shared by participants in the project's online community to understand their perspectives about their experiences with TOEP. Our findings show that participants felt that they gained knowledge from the experiences of peers in the community. Many faculty stated that they integrated technology into their courses while they were participating in the project, or they expressed explicit plans to do so in the future. Many participants also expressed a desire to continue to learn about emerging technologies after their formal participation concluded.
Going the Distance - Online Course Performance and Motivation of Distance-Learning Students
Authors: Hobson Tiffaney D , Puruhito Krista Kay 
Published: December 2018

This study was designed to better understand what drives the learning and performance of students enrolled in distance-learning courses. Between 1999 and 2008, the number of students enrolled in at least one online course increased from 10% to 24% (NCES, 2014). In 2015, the number of students enrolled in at least one distance-learning course approached 6 million, with close to half of those students enrolled in programs that are exclusively online (NCES, 2018; Allen & Seaman, 2017). This enrollment growth, however, is coupled with an alarmingly high attrition rate - a rate as high as 50% greater than campus-offered programs (Willging & Johnson, 2009). As GPA and course performance have been linked to distance-learning persistence and retention, we found it imperative to explore differences in motivational orientations as they relate to passing and failing status for an individual course. To do so, we surveyed distance learning students and identified correlations between motivational constructs such as instrumentality, self-efficacy, connectedness, use of knowledge building strategies, and final course performance. Differences related to gender and major/non-major status are also reviewed and discussed. These findings offer insights into next steps for research, but also inform teaching practice.