bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Electrochemical Performance of NiCo‐Layered Double Hydroxides: Optimal Synthesis Conditions and Supercapacitor Applications
Authors: Li Rui‐Yu , Shen Xin‐Yuan , Li Jia , Zhao De‐Peng , Zhao Rong‐Da , Wu Fu‐Fa 
Published: November 2024

AbstractIn the quest for high‐performance supercapacitor electrode materials, layered double hydroxides (LDHs) containing transition metals, particularly nickel–cobalt layered double hydroxides (NiCo‐LDH), have garnered significant attention due to their distinctive structural and electrochemical properties. In this study, five different temperatures, five distinct reaction times, and four varied Ni:Co ratios to determine the optimal reaction conditions are established. Utilizing these parameters, NiCo‐LDH via a one‐step hydrothermal method is synthesized. Under optimal conditions the specific capacitance reaches 400.2 C g−1 at a current density of 1 A g−1. The assembled supercapacitor has a high energy density of 51.59 µWh cm−2 at a power density of 1.125 mW cm−2. After 10 000 cycles, the capacity retention is 70%, indicating good cycling stability and demonstrating potential for application in supercapacitors. These tests provide theoretical and data‐based support for subsequent experiments and present new opportunities for advancing energy storage and conversion technologies.
An Extended Phenotype of PPP1R13L Cardiocutaneous Syndrome
Authors: Coudert Alicia , Thevenon Julien , Testard Quentin , Satre Véronique , Harbuz Radu , Bouvagnet Patrice , Rabattu Pierre‐Yves , Coutton Charles , Le Tanno Pauline 
Published: November 2024

ABSTRACTDilated cardiomyopathy (DCM) is a rare disease in children and a leading cause of heart failure. There are numerous causes of DCM including genetic causes leading to isolated or syndromic presentations, with a wide variety of implicated genes. Among them, PPP1R13L is associated with a recessive syndrome leading to cardiac anomalies with skin, teeth, and hair abnormalities. Fifteen patients have been described so far. We report a patient born to unrelated parents with early‐onset and progressive DCM, skin appendage anomalies, and an anorectal anomaly. Her late brother shared the same phenotype. Exome sequencing revealed biallelic loss‐of‐function (LoF) variants of PPP1R13L in the proband, also present in her affected brother. To our knowledge, anorectal anomalies had never been previously described in PPP1R13L mutated individuals. As exome sequencing did not identify any other candidate variant to explain this malformation, this feature may expand the phenotype of PPP1R13L LoF disorder.
Transcriptomic and epigenomic profiling reveals altered responses to diesel emissions in Alzheimer's disease both in vitro and in population‐based data
Authors: Saveleva Liudmila , Cervena Tereza , Mengoni Claudia , Sima Michal , Krejcik Zdenek , Vrbova Kristyna , Sikorova Jitka , Mussalo Laura , de Crom Tosca O. E. , Šímová Zuzana , Ivanova Mariia , Shahbaz Muhammad Ali , Penttilä Elina , Löppönen Heikki , Koivisto Anne M. , Ikram M. Arfan , Jalava Pasi I , Malm Tarja , Chew Sweelin , Vojtisek‐Lom Michal , Topinka Jan , Giugno Rosalba , Rössner Pavel , Kanninen Katja M. 
Published: November 2024

AbstractINTRODUCTIONStudies have correlated living close to major roads with Alzheimer's disease (AD) risk. However, the mechanisms responsible for this link remain unclear.METHODSWe exposed olfactory mucosa (OM) cells of healthy individuals and AD patients to diesel emissions (DE). Cytotoxicity of exposure was assessed, mRNA, miRNA expression, and DNA methylation analyses were performed. The discovered altered pathways were validated using data from the human population‐based Rotterdam Study.RESULTSDE exposure resulted in an almost four‐fold higher response in AD OM cells, indicating increased susceptibility to DE effects. Methylation analysis detected different DNA methylation patterns, revealing new exposure targets. Findings were validated by analyzing data from the Rotterdam Study cohort and demonstrated a key role of nuclear factor erythroid 2–related factor 2 signaling in responses to air pollutants.DISCUSSIONThis study identifies air pollution exposure biomarkers and pinpoints key pathways activated by exposure. The data suggest that AD individuals may face heightened risks due to impaired cellular defenses.Highlights
Healthy and AD olfactory cells respond differently to DE exposure.
AD cells are highly susceptible to DE exposure.
The NRF2 oxidative stress response is highly activated upon air pollution exposure.
DE‐exposed AD cells activate the unfolded protein response pathway.
Key findings are also confirmed in a population‐based study.
Self‐adaptive Coordination Evolution Mediated Pore‐Space‐Partition in Metal–Organic Frameworks for Boosting SF6/N2 Separation
Authors: Ruan Heng‐Yu , Wu Xue‐Qian , Liao Cai‐Lian , Wang Meidi , Wu Ya‐Pan , Hai Guangtong , Zhao Xiang , Li Dong‐Sheng 
Published: November 2024

AbstractThe controllable and precise structural regulation of metal–organic frameworks (MOFs) based on isoreticular chemistry is an effective strategy for creating functional material platforms, such as efficient porous adsorbents. Herein, for the first time, mediated by an unprecedented self‐adaptive coordination evolution (SACE) on pseudo‐D2h‐symmetric [M4(μ3‐O)2(COO)6] (M=Mn/Fe) clusters, two pore space partitioned MOFs (CTGU‐47‐Mn/Fe, CTGU=China Three Gorges University) have been successfully constructed. Owing to the more confined adsorption space and dense binding sites produced by pore space partitioning (PSP), the CTGU‐47‐Mn/Fe exhibit significantly enhanced performance in the capture or recovery SF6 (greenhouse/electronic specialty gas) from SF6/N2 mixture compared to their non‐partitioned homologous structures (CTGU‐46‐Mn/Fe) with adsorption selectivity increased from 37/72 to 634/157 (v/v, 10/90, 100 kPa). The theoretical calculations also elucidated that the implementation of PSP within CTGU‐47‐Mn/Fe leads to dramatically strengthened binding affinity for SF6 over N2 through extra multiple F⋅⋅⋅H interactions. This study represents a valuable advance in crystal engineering field: the SACE of polynuclear metal clusters is expected to be useful in the structural regulation of MOFs and the fabrication of advanced porous adsorbents.
Self‐Assembled Bent Perylenediimides
Authors: Wang Rui , Qian Baiyang , Xu Yuchuan , Zhao Di , Chen Qiqi , Wei Yifei , Zhang Cankun , Liang WanZhen , Jiang Yun‐Bao , Zhang Hui‐Jun , Lin Jianbin 
Published: November 2024

AbstractThe properties of π‐functional materials are predominantly influenced by both their molecular structures and interactions between π‐systems. Recent advancements have focused on modifying the geometry or topology of π‐molecules from planar to nonplanar conformations to tailor molecular properties. However, the interactions among nonplanar π‐molecules remain largely unexplored, likely due to the significant reduction in contact surfaces arising from their curved structures. Herein, we investigated the electro‐optical properties and π‐stacking behaviors of a series of bent perylenediimides (B‐PDIs) with gradual changes in bending angles, achieved by altering the lengths of linear alkyl chains connecting the two nitrogen positions of each PDI. Curvature‐dependent self‐assembly of these bent PDIs is observed, which is primarily driven by dipole‐dipole interactions rather than dispersion forces. More importantly, fine‐tuning intermolecular coupling through bending enables excited‐state symmetry‐breaking charge separation in [n]B‐PDIs (n = 16, 12) in the crystalline solid state.
Regulation of Coordination Environment Over Cu Sites: Triggering the Efficient Selective Catalytic Reduction of NOx Using NH3 as Reductant
Authors: Zhao Jiao , Li Zhifang , Yang Ruichao , Zhang Zhen , Liu Changyu , Cui Jinxing , Ma Yuanyuan , Yang Changlong 
Published: November 2024

ABSTRACTThe design of the controlled coordination environment over Cu sites for selective catalytic reduction of NOx using NH3 as reductant (NH3‐SCR) is still challenging. A series of dispersed Cu catalysts with different coordination environments were prepared by metal‐template/metal‐ion exchanged method and random grafting method. Meanwhile, their NH3‐SCR catalytic performance was explored. The catalyst C/T9‐M, prepared through metal‐template/metal‐ion exchanged method, achieved relatively good activity with the NOx conversion of ~100% in the temperature region of 250°C°C–400°C. It was ascribed to C/T9‐M containing a higher amount of the isolated Cu2+ and without occurring the direct oxidation of NH3 to NO at high temperature. On the contrary, C/T9‐R synthesized using random grafting method demonstrated more outstanding NH3‐SCR performance with the NOx conversion of ~100% in the temperature region of 200°C°C–350°C due to more [Cu(OH)]+. Our experimental results confirmed that the active [Cu(OH)]+ was capable of facilitating the low‐temperature activity for NH3‐SCR and the isolated Cu2+ facilitates NOx conversion under high temperature. In addition, compared with the C/T9‐R catalyst, the C/T9‐M catalyst had less Cu loading, which laterally proved that controlling the coordination environment of Cu sites could effectively improve the NH3‐SCR performance under high temperature. What's more, C/T9‐M had more glorious the resistance of H2O and SO2 than C/T9‐R. This work furnishes reformatory pathway for the invention of noticeable NH3‐SCR catalysts. It is expedient for academic and practical applications in the future.
Disulfide‐Functionalized Polyurethanes Serve as UV‐Curable One‐Component Adhesives
Authors: Liu Ziqiang , Ju Changzheng , Li Peilin , Yan Zhi‐Chao , Zhang Zhen 
Published: November 2024

ABSTRACTOne‐component polyurethane (PU) adhesives typically cure through the reaction between –NCO functional groups and moisture in ambient air, requiring moisture‐free storage. In this study, we present a novel one‐component polyurethane adhesive that cures via UV irradiation and is resistant to moisture during storage. The polyurethanes were synthesized by polymerizing diisocyanate, polytetramethylene ether glycol, and bis(hydroxymethyl)‐1,2‐dithiolane. The incorporated dithiolane moieties, inherently photo‐responsive, enable efficient cross‐linking under UV light without the need for external photo‐initiators or light absorbers. Rheological analysis of both uncured and cured polyurethanes confirmed their suitability for adhesive applications. The 4,4′‐methylene bis(cyclohexyl isocyanate)‐derived polyurethane exhibited the highest tensile strength, with stress at a break of 3.49 ± 0.24 MPa and an elongation of 74.38% ± 7.47%. This polyurethane served as an adhesive and achieved robust bonding performance on various transparent plastic sheets, with a bonding strength of up to 5.88 ± 0.49 MPa on polyvinyl chloride (PVC) substrate.
PBT‐Based Fluorescent Copolyesters With Wide Gamut Fluorescence and Excellent Mechanical Properties
Authors: Ma Le‐Le , Du Ming‐Xuan , Xiao Yao‐Nan , Wu Shao‐Hua , Liu Jia‐Jian , Li Chun‐Cheng 
Published: November 2024

ABSTRACTRecently, non‐traditional intrinsic luminescence (NTIL) polymers containing ester groups have gained widely attention due to their potential in fluorescence materials application. As a common engineering plastic, polybutylene terephthalate (PBT) possesses traditional luminescent center benzene ring and non‐traditional luminescent center carbonyl group on the molecular chain, yet the fluorescence characteristics of PBT have rarely been reported. Herein, a series of PBT‐based copolyesters PBTxAy were prepared by a two‐step melt polycondensation in this work. By introducing flexible aliphatic diacid into PBT chain, PBTxAy copolyesters exhibited unexpected fluorescence properties under the excitation of 350 nm UV lamp. Besides, the fluorescence emission wavelength of PBTxAy copolyesters could be tunable from 439 to 468 nm by changing the chemical structure. Consequently, this study provides a facial and economical approach to prepare PBT‐based fluorescent copolyesters, which exist a great potential as fluorescent engineering plastic in the future.
Light‐Induced Transformations of Donor‐Donor Diazo Compounds Derived from N‐Sulfonylhydrazones
Authors: Yamini Pokhriyal , Junaid Mohammad , Yadagiri Dongari 
Published: November 2024

AbstractThe donor‐donor carbene chemistry field is underdeveloped and often relies on harsh reaction conditions, utilizing either thermal or oxidative process with or without transition‐metal catalysts. In this review, we discussed the synthesis and transformation of donor‐donor diazo compounds from N‐sulfonylhydrazones in the presence of light and base. The N‐sulfonylhydrazones are easily accessible from the corresponding carbonyl compounds and sulfonyl hydrazides through condensation. The in situ generated N‐sulfonyl anion in the presence of base would undergo the N−S bond cleavage with the aid of light to generate the donor‐donor diazo compounds. The donor‐donor diazo compounds showed various reactivity in the presence of light for the C−C and C−X bond formation, cyclopropanation reactions, and synthesis of nitrogen, oxygen‐containing heterocyclic compounds, which all are discussed under metal‐free conditions.
Exploring the Heterogeneity of Self‐Injurious Behaviors in Autistic Youth: Patterns, Predictors, and Implications for Intervention
Authors: Ferguson Emily F. , Spackman Emily , Cai Ru Ying , Hardan Antonio Y. , Uljarević Mirko 
Published: November 2024

AbstractSelf‐injurious behaviors (SIB) encompass a heterogeneous set of self‐inflicted aggressive behaviors that are highly prevalent in autistic youth. Existing research on SIB in autism spectrum disorder (ASD) has been limited by significant methodological and conceptual inconsistencies. Thus, the current study leveraged item‐level data capturing the severity of unique SIB topographies to further understanding of factors associated with distinct SIB in a sample of 582 autistic youth (Mage = 12.12, SDage = 3.68; range: 3–19 years; 13% females). Results suggest variation in severity endorsements for specific SIB topographies amongst autistic youth, such that 30%–50% of caregivers endorsed slight to very serious concern regarding the SIB topographies of bites nails/skin/fingers, scratches self, hits head/face/neck, bangs head against things, and picks skin. Generalized additive models demonstrated distinct patterns of associations between each SIB topography and dysregulation, sensory hypersensitivity, age, sex, IQ, and language level. Findings underscore the importance of exploring SIB as a multifaceted construct to capture unique correlates of distinct SIB that vary in severity and functional impact, which is critical for the development of effective interventions. This study represents an important step towards more individualized characterization of SIB and support for diverse presentations of these behaviors in autistic youth.
Comparison of dU/dQ, Voltage Decay, and Float Currents via Temperature Ramps and Steps in Li‐Ion Batteries
Authors: Azzam Mohamed , Ehrensberger Moritz , Endisch Christian , Sauer Dirk‐Uwe , Lewerenz Meinert 
Published: November 2024

AbstractIn this study, the effect of temperature changes on the voltage decay and current behavior of lithium‐ion cells is investigated, focusing on a comparison between open‐circuit voltage (OCV) measurements and float current
measurements. Using our self‐developed advanced Floater system, the voltage decay rates
from OCV and float current measurements for three different cell types are assessed. Temperature ramps and steps, ranging from 5 °C to 50 °C, are applied to capture the impact of entropic effects and aging mechanisms. Both methods effectively capture aging dynamics, showing strong agreement between ramp and step measurements. Deviations arise only in cases of strong entropy effects due to differences in measurement strategies. The findings confirm that float currents do not introduce additional aging beyond that captured by OCV measurements. The relationship between OCV and float current is governed by differential capacity
, which varies with cell voltage and temperature. Furthermore, strong deviations from classical differential voltage analysis but high agreement with local pulse measurements are observed, especially at low depths of discharge. This can be explained by the hysteresis effect of graphite. These findings highlight the benefits of high‐precision float current measurements in aging studies, particularly in contrast to simpler OCV methods.
Synthetic biology‐enhanced microalgae for biofuel production: a perspective
Authors: Makepa Denzel Christopher , Chihobo Chido Hermes 
Published: November 2024

AbstractThe development of microalgae‐based biofuels has emerged as a promising solution to address the pressing global challenges of climate change, resource scarcity, and the need for renewable energy sources. Microalgae possess unique capabilities that make them an attractive feedstock for biofuel production, including their ability to capture and sequester carbon dioxide, their efficient use of water and land resources, and the potential for them to utilize waste streams as nutrient sources. This paper provides a comprehensive overview of the environmental and economic implications of microalgae‐derived fuels, highlighting the key benefits and remaining challenges. The integration of synthetic biology to enhance microalgae strains, optimize cultivation and processing, and diversify revenue streams is explored as a means to address the economic barriers to large‐scale commercialization. As research and development in this field continue to progress, the future prospects of microalgae‐based biofuels are discussed, underscoring their potential to reshape the global energy landscape towards a more sustainable and economically viable future.
Representations of schooling and childhood during the COVID‐19 pandemic in England
Authors: Bacon Kate , Frankel Sam 
Published: November 2024

AbstractDuring the COVID‐19 pandemic, questions abounded about how best to support children during the ‘new normal’ where homes, often instead of schools, were identified as the usual sites of learning. Educational research has explored the impact of COVID‐19 on schools, education and learning, and childhood studies research has shown the impact on children's rights and paid attention to how constructs of childhood have shaped government responses. In this paper, we bring these fields together through exploring constructions of childhood alongside those of schooling. We systematically analyse the representations of schooling and childhood in 72 BBC news articles published on 1 June—the day that primary schools started to reopen in England. Our findings show that the dominant ‘frames’ of reporting centred around risk and fear. COVID‐19 risks exist to health and safety, to children's education and to childhood more generally. The news media portrayed schooling as synonymous with learning, children as passive and childhood as a time of both happiness and ‘loss’. We argue that these normative discourses exploit children as symbols of hope, conceal alternative ways of thinking about learning and are restrictive and unreflective of children's agency and real‐life experiences. In the aftermath of the pandemic, academics and policymakers need to continue to debate and explore the nature of learning and children's perspectives on school in order to critically examine the current system of schooling.
Smoothed Estimation on Optimal Treatment Regime Under Semisupervised Setting in Randomized Trials
Authors: Jiao Xiaoqi , Peng Mengjiao , Zhou Yong 
Published: November 2024

ABSTRACTA treatment regime refers to the process of assigning the most suitable treatment to a patient based on their observed information. However, prevailing research on treatment regimes predominantly relies on labeled data, which may lead to the omission of valuable information contained within unlabeled data, such as historical records and healthcare databases. Current semisupervised works for deriving optimal treatment regimes either rely on model assumptions or struggle with high computational burdens for even moderate‐dimensional covariates. To address this concern, we propose a semisupervised framework that operates within a model‐free context to estimate the optimal treatment regime by leveraging the abundant unlabeled data. Our proposed approach encompasses three key steps. First, we employ a single‐index model to achieve dimension reduction, followed by kernel regression to impute the missing outcomes in the unlabeled data. Second, we propose various forms of semisupervised value functions based on the imputed values, incorporating both labeled and unlabeled data components. Lastly, the optimal treatment regimes are derived by maximizing the semisupervised value functions. We establish the consistency and asymptotic normality of the estimators proposed in our framework. Furthermore, we introduce a perturbation resampling procedure to estimate the asymptotic variance. Simulations confirm the advantageous properties of incorporating unlabeled data in the estimation for optimal treatment regimes. A practical data example is also provided to illustrate the application of our methodology. This work is rooted in the framework of randomized trials, with additional discussions extending to observational studies.
In Situ Study on Biodegradation Differences Between Dissolved Phenanthrene and Methylphenanthrene Using First Derivative Synchronous Fluorescence Spectrometry With Double Scans
Authors: Li Mengshuo , Chen Jingjing , Zhu Yaxian , Zhang Yong 
Published: November 2024

ABSTRACTA rapid and highly sensitive first derivative synchronous fluorescence spectrometry with double scans was successfully optimized for the simultaneous determination of dissolved phenanthrene (Phe), 1‐methylphenanthrene (1‐MP), and 3‐methylphenanthrene (3‐MP) and their metabolites such as 1‐hydroxy‐2‐naphthoic acid (1H2NA) and salicylic acid (SA) in the biodegradation processes of Phe, 1‐MP, and 3‐MP by Novosphingobium pentaromativorans US6‐1. Δλ of 55 and 109 nm were selected for Phe, 1‐MP, 3‐MP, 1H2NA, and SA, respectively. The intensities of the first derivative synchronous fluorescence detected at λex of 289, 292, 291, 354, and 312 nm for Phe, 1‐MP, 3‐MP, 1H2NA, and SA varied linearly with the concentrations of them in the ranges of 0.20 × 10−7–44.89 × 10−7, 0.20 × 10−7–13.04 × 10−7, 0.20 × 10−7–13.04 × 10−7, 0.22 × 10−7–76.30 × 10−7, and 0.11 × 10−7–52.00 × 10−7 mol/L. The limits of detection were 0.11 × 10−9, 0.30 × 10−9, 0.27 × 10−9, 0.33 × 10−9, and 2.90 × 10−9 mol/L for Phe, 1‐MP, 3‐MP, 1H2NA, and SA, respectively, with RSD less than 2%. The method was successfully applied in situ to detect the instantaneous concentrations of the PAHs and their metabolites, especially SA, during their biodegradation processes under simulated conditions in the lab. The results demonstrated that the upper metabolic pathways of 1‐MP and 3‐MP by US6‐1 were distinctly different from that of Phe owing to steric hindrance of the methyl group.
Design and Synthesis of Butylphthalide‐Hydroxycinnamic Acid Hybrid Derivatives as Potential Antiplatelet Agents
Authors: Yang Ya , Jia Zhen , Ma Taigui , Yu Qinyang , Tang Lei , Li Yong , Fan Lingling 
Published: November 2024

AbstractThirty‐eight novel butylphthalide‐hydroxycinnamic acid hybrid derivatives were designed and synthesized to discover effective antiplatelet agglutination drugs. Among these compounds, 3 o gave the optimal inhibitory activity against AA‐induced platelet aggregation in vitro and also exhibited better inhibition than the precursor 3‐n‐butylphthalide (NBP) against thrombin‐induced platelet contraction, carrageenan‐induced tail thrombosis, and FeCl3‐induced common carotid artery thrombosis. Further investigations on the anti‐ischemic stroke activity revealed that compound 3 o exhibited a remarkable protective effect against ischemic/reperfusion brain injury. The PAMPA‐BBB permeability and liver microsomal stability tests indicated that compound 3 o could traverse the blood‐brain barrier and possessed favorable metabolic stability. This research provides a new candidate compound for treating and preventing cerebrovascular diseases caused by thrombosis.