bluuebunny/crossref_metadata_2025_split huggingface dataset:
Artistas 21. Articulaciones Extensión-Docencia-Investigación y Comunidad a través del Patrimonio lujanense
Authors: Paredes Mariana , Lubo Jonatan 
Published: December 2024

La localidad de Luján (provincia de Buenos Aires, Argentina), es rica por su protagonismo histórico, cultural y religioso. Entre sus instituciones más destacadas se encuentra el Museo Municipal de Bellas Artes “Fernán Félix de Amador” (MMBA), cuyo rol ha ido mutando en las últimas décadas al de centro cultural y salón de usos múltiples, ante la falta de presupuesto y políticas públicas que jerarquicen su patrimonio y fomenten modos de acercamiento al mismo. En este trabajo se presentan los resultados de cinco años de labor, llevada a cabo a través del Proyecto de Extensión Universitaria Artistas 21, radicado en la Universidad Nacional de las Artes, basado en una propuesta interdisciplinaria y multisectorial que involucró a un numeroso equipo de trabajo. El mencionado proyecto estuvo destinado al fortalecimiento de las misiones del MMBA en el marco de su 60º aniversario. Para su abordaje, trabajamos en tres ejes: 1) Patrimonio, 2) Territorio y 3) Extensión-Investigación-Docencia, a través de los cuales se propuso articular la producción académica, la investigación y las prácticas profesionales, con la puesta en valor de dos donaciones: Rebuffo y Leone, para así presentar estos materiales a la comunidad y promover el acceso al patrimonio local. Entre los principales logros alcanzados destacamos el trabajo colectivo y el aprendizaje transdisciplinar, las articulaciones universidad-museo-escuela-comunidad, la implementación de becas, la curricularización de prácticas extensionistas; para finalmente ofrecer este importante acervo a la comunidad y construir, junto con docentes de la región, caminos de abordaje, apropiación e interpretación orientados a la construcción de saberes situados e identidades compartidas.
Los procesos de curricularización de la extensión en universidades argentinas. Concepciones, valoraciones y sentidos
Authors: Macchiarola Viviana , Cecchi Néstor , Oyarbide Rodolfo Fabricio 
Published: December 2024

Desde la primera década de los años 2000, varias universidades públicas de América Latina y de Argentina inician un proceso de curricularización de la extensión a través de la implementación de Prácticas Sociales Educativas en sus diferentes denominaciones, en el marco de los idearios de Compromiso Social, Extensión Crítica e Integralidad. A partir de la importancia este movimiento instituyente, el Observatorio sobre Compromiso Social Universitario “Jorge Castro” del Centro de Estudios Sindicales y Sociales de la Agremiación Docente Universitaria Marplatense, realizó un estudio con los objetivos de caracterizar los aprendizajes de las/os estudiantes al participar de prácticas de curricularización de la extensión, describir las metodologías empleadas, valorar los procesos de participación e interacción entre actores sociales y universitarios y reconocer logros y limitaciones de los procesos de curricularización de la extensión. Para ello, se llevó a cabo el estudio con un enfoque cuantitativo mediante encuesta realizada a estudiantes y graduados de once universidades nacionales que transitaron por estas experiencias. Los resultados evidencian valoraciones interesantes y esclarecedoras en relación a las perspectivas respecto de las dimensiones comprendidas en el instrumento. Se advierten, por ejemplo, aprendizajes experienciales con integración curricular y ejercicio reflexivo y problematizador sobre el sentido de compromiso social universitario desde la praxis; así como cuestiones que ameritan transformaciones desde la perspectiva extensionista crítica, entre las que se destacan: insuficiente participación de las/os estudiantes en el diseño del dispositivo y de las organizaciones sociales e instituciones extrauniversitarias en la plenitud del proceso.
Can Morphology and Immune Infiltration Predict the Homologous Recombination Deficiency Status in Newly Diagnosed High-Grade Serous Ovarian Carcinoma?
Authors: Kime Amel , Bataillon Guillaume , Treilleux Isabelle , Callens Céline , Selle Frédéric , Heitz Florian , Cinieri Saverio , González-Martin Antonio , Schauer Christian , Lindahl Gabriel , Parma Gabriella , Vergote Ignace , Matsumoto Takashi , Blonz Cyriac , Canzler Ulrich , Mosconi Anna Maria , Guerra Alía Eva María , Pujade-Lauraine Eric , Genestie Catherine , Ray-Coquard Isabelle , Just Pierre-Alexandre 
Published: December 2024

Context.—
A correlation between the morphology of ovarian high-grade serous carcinomas (HGSOCs) and BRCA mutations has been previously reported.

Objective.—
To investigate, beyond BRCA, the association between the morphology of HGSOC and the presence of homologous recombination deficiency (HRD).

Design.—
We reviewed 522 of 806 cases of HGSOC from the PAOLA-1 clinical trial, including 163 cases with tumor BRCA mutation, 345 cases without tumor BRCA mutation, and 14 cases with inconclusive BRCA tests. Regarding HRD status (myChoice HRD Plus assay), 269 cases (52%) were positive (HRD+), 198 (38%) negative (HRD−), and 55 (10%) inconclusive. Morphologic analysis included tumor architecture (with more than 25% of solid, pseudoendometrioid, and transitional patterns defining a SET architecture), tumor-infiltrating intraepithelial lymphocytes (ieTILs), and tumor stromal lymphocytes (sTILs).

Results.—
SET architecture (51% versus 40%, P = .02), high number of ieTILs (16% versus 8%, P = .007) and more than 10% of sTILs (27% versus 18%, P = .02) were associated with tumor BRCA mutation, mostly for tumors with a BRCA1 mutation. These criteria were also associated with HRD status: 54% versus 33% (P &lt; .001) for SET architecture, 14% versus 6% (P = .008) for high number of ieTILs, and 27% versus 15% (P = .003) for more than 10% of sTILs. SET architecture was also significantly associated with HRD+ tumors without tumor BRCA mutation (P &lt; .001) when compared with HRD− tumors. The combination of these 3 criteria showed high specificity (0.99; 95% CI, 0.97–0.99) but low sensitivity (0.07; 95% CI, 0.04–0.10).

Conclusions.—
The morphology of HGSOC correlates with HRD status and BRCA status but cannot substitute for molecular analysis in daily practice.
The Innovation of Pelayanan Unggulan Pemohon Asing Prioritas (IDE-PUNAPI) at Immigration Office Class I TPI Denpasar
Authors: Septyawati Kadek Tari , Yudharta I Putu Dharmanu 
Published: December 2024

The IDE PUNAPI innovation is a service innovation provided to applicants who are ill to the extent that they cannot walk or are unable to come to the Immigration Office. This innovation aims to provide services to the prioritized foreign applicants who are unable to attend scheduled biometric data collection and interviews and to deliver completed foreign passports with the Residence Permit to the applicants. The purpose of this research is to explore the innovation of Pelayanan Unggulan Pemohon Asing Prioritas (IDE PUNAPI) in Improving Public Services at Immigration Office Class I TPI Denpasar. This study employs a qualitative research method with data analysis techniques, including descriptive analysis and data analysis methods such as data analysis, data reduction, data presentation, and drawing conclusions. The research findings conclude that the IDE PUNAPI public service innovation at Immigration Office Class I TPI Denpasar has been well-implemented. This is evident in the relative advantages demonstrated through the significant advantages of the IDE PUNAPI service innovation received by the public. The update in this research compared to previous studies lies in the research location and the research object, focusing on the service innovation.
ISOLATION OF BACTERIAL STRAINS FROM AKRA SOIL OF DISTRICT BANNU AND THEIR BIODEGRADATION CAPABILITIES
Authors: Shakeeb Ullah  , Naila Seemab  , Inam Ullah Khan  , Muhammad Saqib  , Anila Khan  , Sana Ullah  
Published: December 2024

Background: Different strategies are present which allow identification of bacteria in different environments. The current gold standard is to culture the bacteria and identify them based on their morphological and metabolic characteristics. Objectives: The present study was designed to isolate bacterial strains having environmental role to degrade various pollutants from Akra soil samples, District Bannu, KPK, Pakistan. Microbial biodegradation is important phenomenon and has attracted attention of the researcher. Methods: Total 6 bacterial strains designated IOM-40, IOM-41, IOM-42, IOM-43, IOM-44 and IOM-45 were isolated. The isolated organisms were identified based on morphological, physiological and genetic characteristics. The isolated organisms were able to grow on T5, TSA, and nutrient agar media. Results: Optimum growth was recorded at 37–45°C, NaCl concentrations (0-0.5%) and at pH 7.0–7.2. Temperature 45°C and medium T5 were best for isolation of bacteria from arid environment of Akra soil. Strains IOM-41 and IOM-45 were rod-coccus shaped and Gram-staining-positive. Bacteria IOM-40 and IOM-43 were Gram-staining-positive and rod shaped. Organisms IOM-42 and IOM-44 were Gram-staining-negative and rod shaped. Conclusion: Organisms IOM-41, IOM-44 and IOM-45 were found possessing biodegradation properties. Isolation of bacteria from such arid environment could be used to mitigate environmental pollution.
. Diagnostic value of HMGB-1 and Acetylcholinesterase in Assessing the Prognosis of Patients with Acute Pancreatitis
Authors: Li Yan 
Published: December 2024

Aim: Acute pancreatitis (AP) is a disorder of tissue digestion caused by abnormal activation of pancreatic enzymes, which may lead to multi-organ failure and ultimately death as the disease progresses. How to quickly and accurately evaluate the progression of AP has always been a hotspot and difficulty in clinical research.
Methods: Sixty-four AP patients admitted to our hospital from August 2022 to June 2023 and 60 concurrent healthy people were selected as the research subjects, with AP patients as the observation group and healthy people as the control group. Using kits from Wuhan Fine Biotechnology Co., Ltd., an enzyme-linked immunosorbent assay (ELISA) was carried out to measure HMGB-1 and AChE levels. In addition, an automatic biochemical analyzer was utilized to quantify the levels of nutritional proteins albumin (ALB), transferrin (TRF), and total protein (TP) in the observation group.
Results: Compared with the control group, the HMGB-1 in the observation group was higher while the AChE was lower (P<0.05). ROC curve analysis showed that when HMGB-1 was less than 7.25 mg/L, the sensitivity and specificity for diagnosing AP were 89.06% and 51.67%, respectively (P<0.05); when AChE was less than 6.18 U/L, the sensitivity for diagnosing AP was 43.75% and the specificity was 90.00% (P<0.05). Using the joint detection Log(P)=-1.736+(0.645×HMGB-1)+(-0.454×AChE), it was found that HMGB-1+AChE had a sensitivity of 48.44% and a specificity of 88.33% for the diagnosis of AP (P<0.05, cut-off>0.639,)

Conclusion: In this study, we found elevated HMGB-1 expression in AP and reduced acetylcholinesterase (AChE), suggesting that both of them may be involved in the occurrence and development of AP. Meanwhile, the two demonstrated excellent diagnostic efficacy in the onset and poor prognosis of AP, and were closely related to AP progression, confirming their potential as new clinical indicators for AP. Due to the self-digestion by pancreatic enzymes, the nutritional metabolism of AP patients is disrupted, so protein loss is also a focus of attention. In this study, we also found a negative correlation of nutritional protein levels with HMGB-1 in AP patients and a positive correlation between them with AChE, further supporting the relationship between the two and AP progression. The findings can lay a reliable foundation for future research on the diagnosis and treatment of AP based on HMGB-1 and AChE.
Multifunctional Agriculture in Plantation as Solution Towards Food Security in National Agriculture Policy 2.0 (NAP 2.0) from the Selected Government Agencies Perspective: Case Study in Pekan Nanas Johor
Authors: Wahid Nurul Farehah , Hassan Mohd Sayuti , Apin Ludi , Mohd Shafiei Mohd Wira 
Published: December 2024

NAP 2.0 is a national policy regarding agriculture that has been devised recently in Malaysia. The policy centred on the issue of food security. Therefore, the purpose of this study is to look into the selected government agency's perspective on establishing multifunctional agriculture in the plantation as a solution to food security issues as presented in NAP 2.0 in the case study area. Qualitative interviews along with semi-structured questions were presented to the selected government agencies. The finding of this study shows that multifunctional agriculture has already been familiarize inside the agriculture industry in plantation areas in Malaysia however, it will require a bit more boost and awareness in terms of environmental factors. Positively, the selected government agencies believe that multifunctional agriculture in plantation areas will be able to become a solution to food security issues as raised in NAP 2.0.
Fully Automating the Administrative Act and its Accompanying Risk
Authors: Tskhadadze Ketevan 
Published: December 2024

In recent decades, technological innovations have significantly changed the behavior of the state and society. Consequently, technological development has had a huge impact on public administration activities, since the development of technology and their integration are mostly related to the need for electronic governance[1]. Digitization of processes, switching to electronic forms, and sometimes automation have become necessary. Digitalization and automation must be discussed independently of each other as digitalization of the same digital governance is an important prerequisite for automating the public administration process[2].
The article analyzes the extent to which the automated decision meets the requirements of the administrative act and how the automated actions of the state affect the procedures and its basic principles. The article refers to the importance of automated production and the forms of applying an administrative act on its basis, definitions of electronic and automated acts, and the difference between them. The special focus is on the legal problems and challenges of a fully automated act issued by an administrative body in implementing public administration, and its constitutional-legal grounds
[1] E-governance, or digital governance, is associated with the introduction of innovations and technologies in the field of public administration.
[2] Tskhadadze K., E-Government Implementation on the Example of Georgia, TalTech Journal of European Studies, 14(1), 2024, 254.
Referral Institute in Juvenile Justice
Authors: Gobejishvili Nino 
Published: December 2024

Physiological transformation in juveniles from adolescence to adulthood[1],, namely, emotional, cognitive and physiological metamorphosis[2] leads to deviation, and quite often, criminality. Albeit, factors provoking an adolescent to become a delinquent are rarely of a general nature – is not the family as a primary source of socialization[3] playing a vital role in refining the adolescent as a decent society member? It is a question whether primary educational level[4] either friend bunch[5] give an example to juvenile and create inner self[6] which provides adolescent’s compass direction in this or that way?
[1] United Nations Guidelines for the Prevention of Juvenile Delinquency (The Riyadh Guidelines), General Assembly Resolution №45112, Adopted 14 December 1990, Article I.5 (e) <https://www.ohchr.org/en/instruments-mechanisms/instruments/united-nations-guidelines-prevention-juvenile-delinquency-riyadh> [26.05.2022].
[2] Richards K., What Makes Juvenile Offenders different from Adult Offernders? Trends & Issues in Crime and Criminal Justice no. 409., Canberra: Australian Institute of Criminology, 2011 < https://www.aic.gov.au/publications/tandi/tandi409> [26.05.2022].
[3] United Nations Guidelines for the Prevention of Juvenile Delinquency (The Riyadh Guidelines), General Assembly Resolution №45112, Adopted 14 December 1990, Article IV.A (12) <https://www.ohchr.org/en/instruments-mechanisms/instruments/united-nations-guidelines-prevention-juvenile-delinquency-riyadh> [26.05.2022].
[4] Ibid, B.
[5] Juvenile Crime, Juvenile Justice, National Research Council, Institute of Medicine, National Academies Press, Washingtom DC., 2001, 80-83 < https://nap.nationalacademies.org/read/9747/chapter/5#67> [26.06.2022].
[6] Shalikashvili M., Criminology, 3rd Ed., Meridiani, Tb., 2017, 34-35.
Actual Issues of Reform of Georgian National Security Sector’s Accountability and Oversight System
Authors: Alapishvili Levan 
Published: December 2024

By its nature and specific obligations, the security assurance system contradicts external control, oversight and accountability principles, because its significant part and decisions are related to secret activities and documents. Therefore, in the democratic governance of national security and oversight of the activities of security institutions, the role of the Parliament, as the highest standing political authority, acting for the interests of the people is extremely important. The Parliament, as the highest legislator sets scopes for the activity, accountability and control of security institutions.
Efficient parliamentary oversight increases the quality of accountability of security institutions and protects the society from arbitrary, inappropriate or repressive governance.
A democratic governance system requires efficient oversight of secret activities. This objective can be achieved, first of all, via independent, powerful institutions and the system that provides oversight of personal data collection. The oversight is not limited to parliamentary oversight only, the development of governmental, judicial and independent institutions is not less important.
This Paper presents experience and analysis of the development of the oversight system over the activities of the security institutions of Georgia and other democratic countries.
The Paper provides the comparative analysis of experiences of Georgian and foreign countries about the oversight of the activities of security institutions and personal data protection in secret activities. The Paper puts some issues for discussion concerning the actual matters of the reform of the control system over the activities of security institutions, providing the considerations about establishing new, independent oversight institutions.
Strategi Perencanaan dalam Peningkatan Kinerja Pendidik dan Tenaga Kependidikan di SMP PAB 8 Sampali
Authors: Syuaira Geniza Aidilla , Putri Adinda Julia , Dalimunthe Naffa Qaila , Simanjuntak Said Hasian , Darmansah Tengku 
Published: December 2024

Manajemen Pendidik dan Tenaga Kependidikan adalah salah satu tanda dari seberapa baiknya suatu sekolah, di mana manajemen pendidik dan tenaga kependidikan memiliki strategi perencanaan untuk meningkatkan kinerja guru dan tenaga kependidikan. Tujuan dari penelitian ini adalah untuk menjelaskan bagaimana kepala sekolah menggunakan strategi untuk meningkatkan kualitas pendidikan dari perencanaan hingga evaluasi. Metode yang digunakan dalam penelitian ini adalah dengan melakukan wawancara dan observasi. Hasil penelitian menunjukkan beberapa hal, yaitu: (1) strategi yang dilakukan oleh SMP PAB 8 Sampali untuk meningkatkan kinerja guru dan tenaga kependidikan; (2) cara mengelola guru dan tenaga kependidikan secara efektif; (3) kriteria penilaian kinerja guru di SMP PAB 8 Sampali; dan (4) bagaimana kepala sekolah bekerja sama dengan komite untuk meningkatkan kualitas pendidikan. Dengan kata lain, penelitian ini membahas tentang bagaimana sekolah menggunakan strategi untuk meningkatkan kualitas pendidikan melalui manajemen pendidik dan tenaga kependidikan.
Impacto de la Práctica Docente en el Desarrollo del Pensamiento Crítico en Alumnos de Escuelas Primaria Multigrado
Authors: Chablé Chablé Silvia 
Published: December 2024

El trabajo presenta una investigación de tipo cualitativo, tiene como objetivo analizar el impacto de las prácticas docentes en el desarrollo del pensamiento crítico en alumnos de escuelas primaria multigrado. El proceso metodológico aplicado fue el método etnográfico, que se combina con un enfoque descriptivo e interpretativo, centrándose en las experiencias y narrativas de dos sujetos informantes que laboran en escuelas multigrado (bidocente y unitaria) del municipio de Macuspana, Tabasco. Los datos recogidos se obtuvieron a través de entrevistas, para luego ser interpretados y contextualizados. Los resultados obtenidos nos dan muestras de cómo las características y cualidades del docente influyen en la práctica al promover el pensamiento crítico, lo cual incluyen valores y conductas que se fortalecen con la cultura escolar y la conexión con las condiciones sociales y familiares del estudiante en entornos multigrado. Se resalta el papel del docente, la importancia de una formación y actualización en metodologías para promover pensamiento crítico. Concluyendo con aquellas prácticas pedagógicas que impactan en el desarrollo del pensamiento crítico y el significado que atribuyen a sus acciones y al entorno en el que interactúan.
იბადიური ისლამის გავლენა ომანის სასულთნოს შიდა და საგარეო პოლიტიკაზე
Authors: გურეშიძე სიმონ 
Published: December 2024

ჰამასის მიერ ისრაელის წინააღმდეგ 2023 წლის 7 ოქტო­მ­ბ­ერს მოწყობილი ტერაქტის შემდეგ, რომლის საპასუხოდაც ღაზას სექტორში დაწყებული სამხედრო ოპერაცია, რომელიც მეტ-ნაკ­ლები ინტენსივობით ნახევარი წლის გასვლის შემდეგაც გრძე­ლ­დება და თანამდევი მოვლენების გამო, პარალელურად, ირან-ისრ­აელის უკიდურეს დაძაბულობაში გადაი­ზარდა, მსოფ­ლიო ახალი მსხვილ მასშტაბიანი რეგიონული დაპირისპირების რის­კის წინაშე დადგა. სწორედ აღნიშნული ფაქტორების გამო კვლავ ჩნდება კითხვები იმის შესახებ, რომ არსებობს თუ არა ახლო აღმ­ოსავლეთის რეგიონში სხვადასხვა მიზეზებით პერი­ოდულად წამოჭრილი კონფლიქტების დიპლომატიურად გადა­ჭრის სულ მცირე შესაძლებლობა, გვაქვს თუ არა რეგიონში შემა­ვალი ამა თუ იმ ქვეყნების უახლეს ისტორიაში აღნიშნული ფენ­ომენის თვა­ლსაჩინო მაგალითები? რამდენად არის გახსნილი მუს­ლი­მური სამყარო მშვიდობიანი გზით კონფლიქტების გადა­ჭრი­ს­ა­დმი. ასევე რომელი ქვეყანა წარმოადგენს ამ მხრივ ერთ-ერთ ყვე­ლაზე წარმატებულ პრეცედენტს და ისლამში არსებული ძირით­ადი მიმდინარეობებიდან რომელი მათგანია უფრო მოქნილი აღნიშნული გამოწვევების დაძლევის საკითხებში?
ახლო აღმოსავლეთის უახლეს ისტორიაში მოვლენები კალ­­ე­იდოსკოპური სისწრაფით იცვლება. ხშირია მაგალითები, როდესაც გუშინდელი დაპირისპირებული მხარეები ურთიე­რ­თ­ობის ნორმალიზებას ახერხებენ, მაგ. აშშ-ის ექს პრეზიდენტ დონ­­ალდ ტრამპის ადმინისტრაციის მიერ ინიცირებული ისრ­აელს, არაბთა გაერთიანებულ საამიროებს, ბაჰრეინს, მაროკოსა და ოდნავ მოგვიანებით სუდანს შორის დადებული აბრაამის შეთანხმება. არის შემთხვევები, როდესაც პარტნიორული ურთ­იე­რთობები დროებით წყდება და იძაბება. მაგალითად, ყურის თანამშრომლობის საბჭოს წევრ ქვეყნებს შორის 2017 წელს კატ­არის ირანთან კავშირისა და ტერორიზმისთვის ხელშეწყობის ბრალდების ნიადაგზე წარმოქმნილი განხეთქილება, რომელიც 2021 წლამდე გაგრძელდა.