bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pulp health and calcific healing of a complicated crown–root fracture with additional root fracture in a maxillary incisor: A case report
Authors: Li Na , Ren Yue-Yue , Tang Ying , Yang Qi , Meng Tian-Tian , Li Song , Zhang Jing 
Published: November 2024

BACKGROUND
Complicated crown–root fracture (CRF) involves severe injury to the crown, root, and pulp, and may be accompanied by multiple root fractures. The loss of a tooth has lifelong consequences for children and teenagers, but the maintenance of pulp health and the calcific healing of multiple root fractures are rarely reported in the literature.
CASE SUMMARY
This case reports healing of a permanent tooth with complicated crown–root and additional root fractures, in which pulp health was maintained. A 10-year-old girl fell and fractured the root of her maxillary left central incisor at the cervical level. After the coronal fragment was repositioned, the tooth was splinted until the tooth was no longer mobile, 2 years later. Eight years after treatment, the tooth has remained asymptomatic with vital pulp and localized gingival overgrowth. Cone-beam computed tomography revealed not only calcified healing of the CRF but also spontaneous healing in an additional undiagnosed root fracture. The fracture line on the enamel could not be healed by hard tissue and formed a groove in the cervical crown. It was speculated that the groove was related to the localized gingival overgrowth.
CONCLUSION
This case provides a clinical perspective of the treatment of a tooth with a complicated CRF and an additional root fracture.
Challenges and improvement strategies in the hospitalization of chronic multimorbid patients
Authors: Fontalba-Navas Andres , Pozo Muñoz Francisco , Garcia Cisneros Rogelio , Garcia Larrosa Maria Jose , Callejon Gil Maria del Mar , Garcia Delgado Ignacio , Jimenez Martinez Maria Belen 
Published: November 2024

BACKGROUND
Addressing the growing challenge of hospitalizing chronic multimorbid patients, this study examines the strain these conditions impose on healthcare systems at a local level, focusing on a pilot program. Chronic diseases and complex patients require comprehensive management strategies to reduce healthcare burdens and improve patient outcomes. If proven effective, this pilot model has the potential to be replicated in other healthcare settings to enhance the management of chronic multimorbid patients.
AIM
To evaluate the effectiveness of the high complexity unit (HCU) in managing chronic multimorbid patients through a multidisciplinary care model and to compare it with standard hospital care.
METHODS
The study employed a descriptive longitudinal approach, analyzing data from the Basic Minimum Data Set (BMDS) to compare hospitalization variables among the HCU, the Internal Medicine Service, and other services at Antequera Hospital throughout 2022. The HCU, designed for patients with complex chronic conditions, integrates a patient-centered model emphasizing multidisciplinary care and continuity post-discharge.
RESULTS
The study employed a descriptive longitudinal approach, analyzing data from the BMDS to compare hospitalization variables among the HCU, the Internal Medicine Service, and other services at Antequera Hospital throughout 2022. The HCU, designed for patients with complex chronic conditions, integrates a patient-centered model emphasizing multidisciplinary care and continuity post-discharge.
CONCLUSION
This study demonstrates the effectiveness of the HCU in managing patients with complex chronic diseases through a multidisciplinary approach. The coordinated care provided by the HCU results in improved patient outcomes, reduced unnecessary hospitalizations, and better management of patient complexity. The superiority of the HCU compared to standard care is evident in key outcomes such as fewer readmissions and higher patient satisfaction, reinforcing its value as a model of care to be replicated.
Wilson's disease in two siblings from Ecuador: Two case reports
Authors: Carrera Enrique , Alvarado Jonathan , Astudillo Martina , Pillajo Galo 
Published: November 2024

BACKGROUND
Wilson's disease (WD) is a rare metabolic disorder of copper accumulation in organs such as liver, brain, and cornea. Diagnoses and treatments are challenging in settings, where advanced diagnostic tests are unavailable, copper chelating agents are frequently scarce, healthcare professionals lack disease awareness, and medical follow-ups are limited. Prompt diagnoses and treatments help prevent complications, improve patients’ quality of life, and ensure a normal life expectancy. The clinical presentations and outcomes of WD can vary within a single family.
CASE SUMMARY
We present the cases of two siblings (19 and 27 years) from a consanguineous family in rural Ecuador, diagnosed as having WD during a family screening. The male patient, diagnosed at age 19 after his brother’s death from acute liver failure, presented with compensated cirrhosis, neurological symptoms, and bilateral Kayser-Fleischer rings. He developed progressive neurological deterioration during an irregular treatment with D-penicillamine due to medication shortages. His condition improved upon switching to trientine tetrahydrochloride, and his neurological symptoms improved over an 8-year period of follow-ups. The female patient, diagnosed at age 10, exhibited only biochemical alterations. Her treatment history was similar; however, she remained asymptomatic without disease progression over the same follow-up period. We discuss the potential influence of epigenetic mechanisms and modifier genes on the various phenotypes, emphasizing the need for research in these areas to optimize therapeutic strategies.
CONCLUSION
Our patients’ medical histories show how early diagnosis and treatment can prevent disease progression; and, how suboptimal treatments impact disease outcomes.
Rare Metastasis of Prostate Cancer in a Man With Ulcerative Colitis After Creation of an Ileal Pouch
Authors: Zemanek Mark , Powers Joseph Carter , Westbrook Katherine , Dester Emma , Smith Riley , Qazi Taha 
Published: November 2024

ABSTRACT
Prostate cancer is one of the most common globally diagnosed cancers in men. It most frequently metastasizes to bones, lymph nodes, lungs, or the liver. There are limited data investigating the impact of prostate cancer on patients who have undergone ileal pouch-anal anastomosis. We explore the case and the diagnosis of a 68-year-old man with prostate adenocarcinoma that metastasized to the ileal pouch and ultimately required pouch explant. In addition, we discuss the challenges associated with screening and treating prostate cancer in patients with ileal pouch-anal anastomosis.
Utility of Endoscopic Full-Thickness Resection for Refractory Rectal Bleeding in Chronic Radiation Proctitis
Authors: Richter Benjamin I. , Abboud Yazan , Flikshteyn Ben , Hajifathalian Kaveh 
Published: November 2024

ABSTRACT
Severe rectal bleeding is a rare complication of chronic radiation proctitis (CRP). Given CRP's propensity to involve the full thickness of the rectal tissue, we proposed that endoscopic full-thickness resection may be a successful therapeutic modality for treating CRP. A 76-year-old man with multiple comorbid conditions who was not a surgical candidate presented with severe bleeding secondary to CRP that was refractory to all medical and therapeutic interventions. An endoscopic full-thickness resection was performed, which initially resulted in hemostasis, but the patient ultimately developed recurrent rectal bleeding, and endoscopic resection was determined to be unsuccessful.
Potential of California Variety Papaya Leaf Extract (Carica papaya L. California variety) As Bioherbicide of Snake Grass Weed (Cyperus rotundus L.)
Authors: Setiawan Riki , Mu'jijah Mu'jijah , Suyamto Suyamto 
Published: November 2024

Efforts to increase production yields are by controlling weeds. Weeds that often grow and we encounter in cultivated plants are weed grass (C. rotundus). California papaya leaves have the potential to be a bioherbicide because they contain allelochemicals that can inhibit weed growth. This study aims to determine the effect of papaya leaves (C. papaya) on the growth of teki grass (C. rotundus) and determinetheconcentration level of papaya leaf allelopathy that most effectively inhibits the growth of teki grass.The method used was a completely randomized design (CRD) with five replications and four treatmentsof0%, 30%, 50%, and 70%. For data analysis in this study using the SPSS version 25.0 program. Papaya leaf extract (C. papaya) is able to inhibit the growth of weed grass (C. rotundus). The concentration of papaya leaf extract (C. papaya) that most effectively inhibits the growth of weed is 50% concentration with a mortality rate (64%), for the lowest plant heightis50% concentration which is 13.84 cm, for the slowestgrowthrate is 50% concentrationwith a growthrate of -0.16 cm.
An Examination of CXL Memory Use Cases for In-Memory Database Management Systems Using SAP HANA
Authors: Ahn Minseon , Willhalm Thomas , May Norman , Lee Donghun , Desai Suprasad Mutalik , Booss Daniel , Kim Jungmin , Singh Navneet , Ritter Daniel , Rebholz Oliver 
Published: November 2024

CXL-based disaggregated memory systems offer options to expand the memory beyond the limits of a single server via cache-coherent memory expansion cards or memory pools. Especially, In-Memory Database Management Systems (IMDBMSs) can benefit from alleviating two critical constraints: (1) limited memory capacity in a server and (2) long restart time during failover to reload data to memory. However, the usage and effectiveness of CXL memory in enterprise-scale IMDBMSs has yet to be validated.
In this work---for the first time---we investigate dynamic memory expansion employing commercial CXL memory devices for IMDBMSs. Our detailed performance analysis reveals that the performance impact of higher latency and lower memory bandwidth impact depends on the memory access patterns of data structures (cf. (1)). Additionally, we present the feasibility of CXL shared memory between servers to improve restart times during failover (cf. (2)).
Our evaluation shows the effectiveness of CXL memory integrated into the SAP HANA Cloud IMDBMS. OLTP workloads have a negligible performance degradation while OLAP workloads have a wide range of performance degradation. CXL shared memory shows a 40% reduction of the restart time for TPC-H SF10 and 84% potential reduction for TPC-H SF100.
SecretFlow-SCQL: A Secure Collaborative Query Platform
Authors: Fang Wenjing , Cao Shunde , Hua Guojin , Ma Junming , Yu Yongqiang , Huang Qunshan , Feng Jun , Tan Jin , Zan Xiaopeng , Duan Pu , Yang Yang , Wang Li , Zhang Ke , Wang Lei 
Published: November 2024

In the business scenarios at Ant Group, there is a rising demand for collaborative data analysis among multiple institutions, which can promote health insurance, financial services, risk control, and others. However, the increasing concern about privacy issues has led to data silos. Secure Multi-Party Computation (MPC) provides an effective solution for collaborative data analysis, which can utilize data value while ensuring data security. Nevertheless, the performance bottlenecks of MPC and the strong demand for scalability pose great challenges to secure collaborative data analysis frameworks.
In this paper, we build a secure collaborative data analysis system SCQL with a general purpose. We design more efficient MPC protocols and relational operators to meet the demand for scalability. In terms of system design, we aim to implement a system with security, usability, and efficiency.

We conduct extensive experiments on SCQL to validate our optimization improvements: (1) Our optimized secure sort protocol sorts one million 64-bit data in only 4.5 minutes, 126× faster than EMP (9.4 hours). (2) The end-to-end execution time of the typical vertical scenario query is reduced by 1991× from the state-of-the-art semi-honest collaborative analysis framework Secrecy (rewritten with Additive Secret Sharing protocol), with appropriate security tradeoffs. (3) We test the system in the WAN setting with
input size
= 10
7
to demonstrate the scalability. We have successfully deployed SCQL to address problems in real-world business scenarios at Ant Group.
ImputeVIS: An Interactive Evaluator to Benchmark Imputation Techniques for Time Series Data
Authors: Khayati Mourad , Nater Quentin , Pasquier Jacques 
Published: November 2024

With the emergence of The Internet of Things (IoT), smart sensors have become abundant in our daily lives. Failures are very common in those devices, leaving the recorded time series with missing blocks of consecutive values. A cottage industry of imputation algorithms exists, each with different performance tradeoffs. The diversity in time series features, missingness patterns, and algorithms' categories makes it challenging to select the best algorithm.
In this demonstration, we showcase ImputeVIS, an analytical tool for benchmarking imputation algorithms. ImputeVIS provides an optimal configuration of those algorithms by implementing various AutoML parameterization strategies. Moreover, it uncovers the behavior of imputation algorithms by explaining the interplay between time series features and the imputation results. Its interactive web browser interface allows users to simulate real-world sensor malfunctions by contaminating time series with different missing block scenarios, deploy their imputation algorithms, and compare them against various popular imputation families.
SEER: An End-to-End Toolkit for Benchmarking Time Series Database Systems in Monitoring Applications
Authors: Althaus Luca , Khayati Mourad , Khelifati Abdelouahab , Dignös Anton , Difallah Djellel , Cudré-Mauroux Philippe 
Published: November 2024

Time series database systems (TSDBs) are prevalent in many applications ranging from monitoring and IoT devices to scientific research. Those systems are specifically designed to efficiently manage data indexed by time. Because of the variety of workloads, the diversity of time series features, and the sophistication of existing TSDBs, there is no clear way to pick the most suitable system.
In this demo, we introduce SEER, an automated, configurable, and interactive toolkit to evaluate TSDBs. SEER is based on TSM-Bench, a benchmark tailored for time series database systems used in monitoring applications. It implements an end-to-end pipeline for database benchmarking from data generation and feature contamination to workload evaluation. Users can define their portfolios by configuring and parameterizing custom queries, specifying their frequencies, controlling the type and level of data features, and indicating the type of workloads. Moreover, they can deploy new systems and/or reconfigure the pre-installed ones. SEER would process users' requests and gracefully recommend the best system on a use-case basis.
Das Pflichtexemplar in Hessen
Authors: Hammer Angela , Kirschberger Timo , Mayer Martin 
Published: November 2024

Zusammenfassung
Der vorliegende Beitrag gibt einen Überblick über die historische Entwicklung, die aktuellen gesetzlichen Grundlagen, die Rolle der Pflicht für die Bestandserhaltung sowie die Struktur der E-Pflicht in Hessen.
Das Pflichtexemplar in Mecklenburg-Vorpommern
Authors: Unterberger Barbara , Brosowski Gritt 
Published: November 2024

Zusammenfassung
Der Beitrag schildert das Sammlungsprofil der Landesbibliothek Mecklenburg-Vorpommern im Hinblick auf analoge Pflichtexemplare und die entsprechenden gesetzlichen Regelungen und praktischen Erfordernisse. Darüber hinaus beschäftigt er sich mit den erforderlichen Prozessen und Entwicklungen, um in Mecklenburg-Vorpommern eine gesetzliche Regelung zur Sammlung von unkörperlichen Medienwerken zu ermöglichen und nimmt dabei dezidiert die Überlegungen und Bemühungen der vergangenen zehn Jahre in den Blick.
Das Pflichtexemplar in Sachsen-Anhalt
Authors: Andres Nico , Özüyaman Susann 
Published: November 2024

Zusammenfassung
Das elektronische Pflichtexemplar in Sachsen-Anhalt wird bereits seit einigen Jahren in einem etablierten Geschäftsgang gesammelt, archiviert und präsentiert. Verändert wird aktuell die Betriebsarchitektur dahingehend, dass die Repositoriumssoftware DSpace eingesetzt und eine Migration der bereits archivierten Medien erfolgen soll. Nach Abschluss der Umstellung sollen weitere Anpassungen in Bezug auf Automatisierung und das Sammelprofil diskutiert werden.
Biological evaluation of CH3OH and C2H5OH of Berberis vulgaris for in vivo antileishmanial potential against Leishmania tropica in murine models
Authors: Ali Qasim , Haleem Sumbal , Ahmad Salman , Jamal Qaisar , Ahmad Tariq , Khan Afshan , Ali Shehzad , Alotaibi Amal , Singh Jyoti , Khan Adil 
Published: November 2024

Abstract
Leishmaniasis is one of the global health issues and is still being handled with costly and sometimes unsuccessful compounds having serious side effects, highlighting the importance of seeking new potent antileishmanial compounds. Herbal medicines have been considered as the main source of prevention and treatment for a wide variety of diseases as well as other photogenetic diseases over the last few centuries. The current study was designed to investigate the in vitro and in vivo antileishmanial efficacy of ethanolic and methanolic extracts of Berberis vulgaris root collected from Kurez region of District Orakzai, Khyber Pakhtunkhwa, Pakistan. Stationary growth-phase metacyclic promastigotes form of Leishmania tropica was incubated in vitro in methanolic and ethanolic extracts using amphotericin B as a positive control. The antileishmanial activity of B. vulgaris extracts was measured after the incubation period using methoxynitrosulfophenyl-tetrazolium carboxanilide assay. For the in vivo study, BALB/c mice were infected with metacyclic L. tropica promastigotes, and lesions appeared after 28 days of inoculum. The results of study research showed that B. vulgaris extract had a powerful antileishmanial activity on promastigotes of L. tropica at different concentrations (5, 10, 25, 50, and 75 μg/mL). The inhibition concentration 50 values for ethanolic and methanolic extracts of B. vulgaris were determined to be 15.37 and 17.55 μg/mL, respectively. In the in vivo activity, it was observed that B. vulgaris ethanolic extract at the concentration of 1.5 mg/kg decreased the lesion diameter in BALB/c infected mice. The ethanolic extract topically and orally reduced the lesion size 0.51 ± 0.023 and 0.56 ± 0.008 mm, while methanolic extract both topically and orally decrease the lesion diameter of 0.63 ± 0.008 and 0.68 ± 0.009 mm relatively, in comparison with negative control (1.45 ± 0.016 mm). Hematological parameters of mice including blood red blood cells, hematocrit, and hemoglobin in mice groups (infected non-treated) were found to be decreased, while the mice group treated with extract demonstrated nearly similar results to non-infected group. It is concluded from the current study that antileishmanial activity of B. vulgaris from Pakistan against L. tropica in both in vitro and in vivo showed a promising antileishmanial activity. This study might be helpful in the control strategies of cutaneous leishmaniasis caused by L. tropica.
The Graphic Anne: Anne Frank Comics as Transnational Lieu de Mémoire
Authors: Gundermann Christine 
Published: November 2024

Abstract
In this essay, I discuss the transformation of Anne Frank’s diary into various forms of media, particularly focusing on comics and graphic novels as transnational lieu de mémoire. The research is based on a private Anne Frank comic collection of more than 40 publications collected from all around the world. I describe how the adaptation of Anne Frank’s story in comics has contributed to shaping the memory culture of the Holocaust and the Second World War on a global scale. I emphasize the significance of Anne Frank as a historical figure and the widespread dissemination of her diary, which has been translated into numerous languages and recognized as a UNESCO world heritage. By following the comic productions of the diary around the world, I explore the role of popular history in gendering victimhood and sacrifice, particularly in the context of the 1950s narrative surrounding Anne Frank and the national memory of the Netherlands. Although the diary was widely present, the comic productions as exemplary access to pop culture reveal an underrepresentation of the Jewish heritage of the Franks and the persecution of Jews as a crime beyond national borders. Furthermore, the comics represent the international success of Anne Frank’s diary, portraying themes of hope, freedom, and optimism, as well as its portrayal as a coming-of-age and first-love story. The comics show how these topics, and Anne’s life and suffering, play out in different popular and memory cultures.
When Comics Become Part of a Thesis Project
Authors: Gandanger Aliénor 
Published: November 2024

Abstract
This article outlines my doctoral thesis project that began in October 2021. Given the interdisciplinary nature of this hybrid doctoral project, the challenge is twofold. First, bridging the gap between a historical analysis of an object of study, using archival research and, second, a self-reflection on the production of a comic strip, its communication and accessibility, both requiring constant adaptation of the methodology. The first part of the thesis is concerned with answering the research questions relating to wartime godmothers during the First World War in France. Numerous sources have been identified to answer these questions. The second part of the thesis is the creation of a fictional comic strip in collaboration with a female cartoonist. Given that this is a work in progress, the article sets out the initial results and highlights the benefits and challenges of this interdisciplinary practice that have been discovered so far.
Cultivating Trees: Lewis Carroll’s Method of Solving (and Creating) Multi-literal Branching Sorites Problems
Authors: Beisecker Dave 
Published: November 2024

Abstract
Lewis Carroll has been credited for developing a “Method of Trees” for solving multi-literal sorites problems, which anticipates several aspects of contemporary “tableau” or tree systems of logical proof. In particular, Carroll’s method pioneers the use of branching paths as a means of displaying or illustrating inclusive disjunction. However, rather than focusing on the respects in which Carroll’s tree diagrams resemble contemporary tree systems, I propose to focus instead on significant aspects in which they differ. In particular, I will show how the sorts of multi-literal sorites problems that Carroll’s method of trees is designed to solve are particularly ill-suited for resolution by more contemporary tree methods. I will also show how Carroll likely used something like this method, not only to solve but also to craft some of the trickier logical puzzles for which he is also famous.
ПРАВА ТА ОБОВ’ЯЗКИ АРБІТРАЖНОГО КЕРУЮЧОГО В ПРЕВЕНТИВНІЙ РЕСТРУКТУРИЗАЦІЇ
Authors: ДЕРЛЮК Василь 
Published: November 2024

Проаналізовано функції арбітражного керуючого у справах про банкрутство з акцентом на процедуру превентивної реструктуризації, а також відмінності підходів до ролі арбітражного керуючого у процедурах санації та превентивноїреструктуризації з урахуванням законопроєкту від 12.10.2023 № 10143 щодо імплементації Директиви Європейського парламенту та Ради Європейського Союзу 2019/1023 і запровадження процедур превентивної реструктуризації. Розглянуто повноваження арбітражного керуючого, порядок призначення, припинення повноважень, гарантування виплати винагороди, умови залучення в превентивній реструктуризації відповідно до законопроєкту. Окремо розглянуто зарубіжний досвід визначення адміністратора превентивної реструктуризації. Дослідження дало підстави сформулювати висновки щодо прав та обов’язків арбітражного керуючого (адміністратора) у превентивній реструктуризації.