bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health-related quality of life in end-stage renal disease patients, using the Missoula-Vitas quality of life index: a multicenter study
Authors: Dimova Rositsa , Keskinova Donka , Tzekov Valeri , Ginova-Noncheva Gergana 
Published: October 2019

Background and aims. Assessment of Health-related Quality of Life in chronic hemodialysis patients (CHD) is a predictive indicator of the outcome of the disease, including mortality and hospitalization. Regular surveys of the quality of life (QoL) in CHD patients have been conducted worldwide, using various, internationally validated and standardized tools, including the Missoula-VITAS Quality of Life Index scale (MVQOLI). The aim of this study was to examine the reliability and validity of the Bulgarian version of the Missoula-VITAS Quality of Life Index-15 (B-MVQOLI-15) and QoL in CHD patients using this instrument.
Methods. Our study was designed as multi-center cross-sectional. It incorporated 263 end-stage renal disease (ESRD) patients on CHD from across the country and applied the B-MVQOLI-15. Internal consistency and convergent validity of the index were assessed. Non-parametric methods were used to evaluate the impact of demographic factors on the different dimensions scores and on the total score. The relationship between the total QoL score, the total MVQOLI-15 score and dimensions scores were measured based on Spearman's rho Correlation Coefficient.
Results. The total MVQOLI-15 score in the study was 16.44, which is slightly above the middle of the index scale. The patients with higher education were less satisfied with the level of their symptom control compared to patients with lower education. However, high education patients seem to manage better with everyday life compared to those with low education. Men seem to feel more satisfied than women when fulfilling their daily activities (Р=0.026). Retired patients and unemployed expressed more satisfaction, compared to the employed (P=0.021). Also, patients on dialysis for over 5 years had lower QoL scores (Р=0.043).
Conclusions. B-MVQOLI-15 is a reliable instrument to measure QoL in Bulgarian patients with CHD. The majority of CHD patients rate their QoL as “Fair“. Four of all five dimensions positively affect the QoL of CHD patients. The most important dimensions positively affecting the QoL of CHD patients were: interpersonal relationships and transcendent factors. Future studies are necessary to assess the adequacy of the delivered dialysis, the level of medico-social care and the needs of ESRD patients treated with CHD in order to improve their QoL.
Islam Inklusif: Konstruksi Pemikiran untuk Dialog Umat beragama di Indonesia
Authors: Tasman Tasman 
Published: October 2019

Artikel ini ingin menjelaskan bahwa Indonesia adalah salah satu negara yang paling pluralistik masyarakatnya. Mayoritas penduduknya memeluk agama Islam, tetapi secara religio-politik dan ideologis, Indonesia bukan negara agama, tetapi juga bukan negara sekular”. Di negeri ini, agama agama diberi ruang untuk bergerak bebas, tumbuh dan berkembang sepanjang tidak melanggar institusi dan batas-batas toleransi antar umat beragama. Komunitas religius yang beraneka ragam tersebut masing-masing, mempunyai orientasi kehidupan sendiri. Negeri ini mengakui pluralitas masyarakat, yang diharapkan oleh konstitusi negeri ini, yaitu dengan keanekaragaman itu pemeluk agama-agama dapat berlomba-lomba dalam berbuat dan mengisi pembangunan. Pancasila sebagai ideologi merupakan titik pertemuan berbagai kelompok kepentingan, karenanya Pancasila adalah hasil kesepakatan nasional dan konsensus masyarakat Indonesia. Pancasila menjadi landasan filosofis toleransi umat beragama di Indonesia, walaupun secara eksplisit bahwa Pancasila sangat dipenuhi oleh nilai-nilai keislaman, ia juga terkadang diiterpretasikan sebagai sekularisme versi Indonesia. Kemajemukan atau pluralitas umat manusia merupakan kenyataan yang tak terbantahkan. Maka pluralitas meningkat menjadi pluralisme, yaitu sistem nilai yang memandang secara positif terhadap kemajemukan itu sendiri, dengan menerimanya sebagai kenyataan dan berbuat sebaik mungkin berdasarkan kenyataan itu. Dalam kerangka inilah kemudian pemikiran Islam inklusif lahir merespon kondisi kebangsaan yang beragam.
Media Sosial, Sumber keberagamaan Alternatif Anak Milenial Fenomena Cyberreligion Siswa SMA Negeri 6 Depok Jawa Barat
Authors: Hatta M 
Published: October 2019

Kegiatan keagamaan di dunia maya marak dilakukan siswa Muslim di Indonesia. Mereka mempelajari Islam di Internet yang menyediakan materi yang melimpah. Siswa bebas memilih materi yang mereka sukai, dan mendengarkan tausiyah dari ustad idola mereka. Ada kecenderungan, mereka menjadikan media sosial sebagai sumber agama alternatif. Penelitian ini bertujuan untuk membuktikan adanya fenomena cyberreligion pada siswa SMA Negeri 6 Depok, Jawa Barat. Ada dua pendekatan analisis yang penulis gunakan pada penelitian ini. Pertama adalah tradisi pemikiran fenomenologis Alferd Schutz terkait aktifitas cyberreligion sebagai sebuah fenomena sosial. Dan kedua, Teori Ketergantungan Media Sandra Ball-Rokeach dan Melvin L. DeFluer (1976) dalam mengungkap aspek ketergantungan siswa pada media sosial dan dampak yang ditimbulkannya. Penelitian ini menggunakan Mixed Methods Research, yakni sebuah metode penelitian gabungan kuantitatif dan kualitatif yang digunakan secara bersama-sama dalam suatu kegiatan penelitian untuk mendapatkan data yang lebih komprehensif, valid, reliabel dan objektif. Beberapa temuan menarik dari penelitian ini mengungkap adanya ketergantungan siswa dalam penggunaan smartphone. Dalam satu hari, siswa minimal menghabiskan waktu 4 jam lebih untuk berselancar di media sosial. Umumnya siswa menyukai tausiyah dari para ustad atau ulama yang dikaguminya. Antusiasme siswa belajar agama dari para ustad pilihannya di media sosial ini, terkadang juga dilandasi oleh kekaguman yang berlebihan dan bahkan cenderung pada kultus individu.
Tracer Study Fakultas Ilmu Dakwah dan Ilmu Komunikasi Universitas Islam Negeri (UIN) Syarif Hidayatullah Jakarta Tahun 2011-2015
Authors: Mauludi Deden 
Published: October 2019

Abstrak: Tracer study atau studi pelacakan merupakan studi tentang lulusan penyelenggara pendidikan. Tracer Study juga menyumbang informasi tentang hubungan antara pendidikan tinggi dan dunia kerja profesional, menilai relevansi pendidikan tinggi, informasi bagi pemangku kepentingan (stakeholders). Hasil Tracer Study dapat digunakan perguruan tinggi untuk mengetahui keberhasilan proses pendidikan yang telah dilakukan terhadap anak didiknya. Penelitian ini bertujuan untuk mengidentifikasikan profil alumniFakultas Ilmu Dakwah dan Ilmu Komunikasi (FIDKOM) UIN Jakarta tahun 2011-2015 yakni seberapa lama mereka studi, masa tunggu alumni, dan sebaran alumni dalam bidang pekerjaannya. Penelitian ini dilakukan secara deskriptif dengan pendekatan survei. Subjek penelitian adalah alumni FIDKOM UIN Jakarta tahun 2011-2015. Ppengumpulan data dilakukan dengan teknik angket dan dokumentasi dari balikan yang disebar. Teknik analisis data yang digunakan adalah analisis deskriptif dengan persentase kemudian dideskripsikan sebagai gambaran profil alumni. asil penelitian Tracer Study menunjukkan bahwa alumni FIDKOM UIN Jakarta menyelesaikan studi di almamaternya dengan waktu 4 tahun sebanyak 56,47 persen. Sementara masa tunggu alumni yang langsung bekerja sebanyak 76,7 persen. Sebaran alumni dalam beberapa bidang pekerjaan, di Lembaga Pers dan Media 14 persen, di Lembaga Dakwah 15 persen, di kantor pemerintahan sebanyak 8,7 persen, pada perusahaan swasta sebanyak 43,29 persen, yang menjadi wirausaha sebanyak 9,64 persen dan lain-lain sebanyak 8,9 persen. Hasil tracer study ini diharapkan menjadi bahan yang berguna bagi pemangku kebijakan untuk peningkatan pelayanan kepada para mahasiswa, pun untuk perbaikan secara menyeluruh. Kata kunci: Tracer Study, Alumni, FIDKOM UIN Jakarta, Pekerjaan
UNGKAPAN MAKNA MAKIAN DALAM BAHASA MINANGKABAU DAN BATAK: STUDI KOMPERATIF
Authors: Siregar Usmala Dewi 
Published: October 2019

Abstract: Invective expression is different from its literal meaning. Invective expression reflect the speaker`s culture, customs, and social and historical backgrounds. Therefore, without knowing a target language, culture aspects as well as expressions, the meaning of expressions can not be concluded from the dictionary definition, speakers of foreign culture often face problems in understanding the actual meaning of the meaning of expressions, especially invective expressions. In the Minangkabau culture that uses invective expressions in their daily conversations, understanding that is not a problem. However, problems may occur when the two different cultures try to understand each other's expressions. Therefore, this study analyzed invective expressions in Minangkabau and Batak languages. In addition, the writer also examined aspects of the culture and situation of the intended expressions used by speakers of each language. The researcher used qualitative methods and the data gets from the informants of both cultures. These findings reveal two categories, namely, first, invective expression in Minangkabau and Batak languages with same literal and actual meaning. Second, invective expression in Minangkabau and Batak languages with same literal meaning but different actual meaning.Abstrak: Makna kiasan berbeda dengan arti harfiahnya. Makna kiasan mencerminkan budaya, adat istiadat penutur, dan latar belakang sosial dan historis. Oleh karena itu, tanpa mengetahui aspek budaya target dan juga ungkapan, makna ungkapan tidak dapat di simpulkan dari definisi kamus, penutur bahasa asing sering menghadapi masalah dalam memahami arti sebenarnya dari makna ungkapan khususnya ungkapan makian. Dalam budaya Minang yang menggunakan ungkapan makian dalam percakapan sehari-hari mereka, memahami itu bukanlah masalah. Namun, masalah mungkin terjadi ketika kedua budaya yang berbeda mencoba memahami ungkapan satu sama lain. Oleh karena itu, penelitian ini menganalisis ungkapan makian dalam bahasa Minang dan Batak. Selain itu peneliti juga meneliti aspek budaya dan situasi tujuan ungkapan di gunakan oleh penutur bahasa masing-masing. Peneliti menggunakan metode kualitatif dan Data bersumber dari informan kedua budaya. Temuan ini mengungkapkan dua kategori yaitu, pertama, Ungkapan makian dalam bahasa Minang dan Batak dengan makna literal dan makna aktual yang sama. Kedua, Ungkapan makian dalam bahasa Minang dan Batak dengan makna literal yang sama tapi makna aktual berbeda.
POLA NARASI PADA ANTOLOGI CERPEN TARIAN SALJU KARABAN
Authors: Haryanti Novi Diah 
Published: October 2019

Abstract: This study aims to look at narrative patterns in the collection of short stories "Karaban Snow Dance" (TSK). From the fifteen short stories, the researchers took five main stories, namely the Karaban Snow Dance (Tarian Salju Karaban), The Fall of a Leaf (Gugurnya Sehelai Daun), Canting Kinanti Song (Tembang Canting Kinanti), Jagoan Men Arrived (Lelaki Jagoan Tiba), and Origami Pigeon (Merpati Origami). Of the five short stories, environmental themes and honesty appear most often. The place setting depicted shows the environment that is close to the author or according to the author's origin. The main characters in the four short stories are children, only one short story Male Hero Tiban (Lelaki Jagoan Tiban/LJK) who uses adult takoh as the main character. The child leaders in LJK only appear in the past stories of the main characters. The five short stories do not show a picture of whole parents (father and mother). The warm relationship between mother and child appears clearly, in contrast to the father-child relationship that is almost negligent. The five short stories also represent how children become heroes for their family, friends, and environment.Abstrak: Penelitian ini bertujuan untuk melihat pola narasi pada kumpulan cerpen Tarian Salju Karaban (TSK). Dari limabelas cerpen yang ada, peneliti mengambil lima cerpen utama yakni “Tarian Salju Karaban”, “Gugurnya Sehelai Daun”, “Tembang Canting Kinanti”, “Lelaki Jagoan Tiba”, dan “Merpati Origami”. Kelima cerpen menampilkan tema lingkungan dan kejujuran. Latar tempat yang digambarkan memperlihatkan lingkuangan yang dekat dengan penulis atau sesuai dengan asal usul penulis. Tokoh utama dalam keempat cerpen tersebut ialah anak-anak, hanya satu cerpen “Lelaki Jagoan Tiban” (LJK) yang menggunakan takoh dewasa sebagai tokoh utama. Tokoh anak dalam LJK hanya muncul dalam cerita masa lalu tokoh utama. Kelima cerpen tersebut tidak memperlihatkan gambaran orangtua utuh (ayah dan ibu). Relasi yang hangat antara ibu dan anak muncul dengan jelas, berbeda dengan relasi bapak-anak yang nyaris alpa. Kelima cerpen tersebut juga merepresentasikan bagaimana anak-anak menjadi pahlawan bagi keluarga, sahabat, dan lingkungannya.
Urine Specific Gravity and the Accuracy of Urinalysis
Authors: Shaikh Nader , Shope Margaret F. , Kurs-Lasky Marcia 
Published: October 2019

BACKGROUND:
A recent study in young infants found that different cutoffs maximized the accuracy of the urine white blood cell count in dilute versus concentrated urine samples. We aimed to confirm this finding and to determine its impact on clinical care.

METHODS:
We conducted a retrospective analysis of data gathered on consecutive children &lt;24 months of age with visits to the emergency department during a 5-year period. We evaluated the accuracy of screening tests for urinary tract infection (UTI) in dilute and concentrated urine samples. We also calculated the number of children who would have been treated differently in a hypothetical cohort of 1000 children presenting with fever had urine specific gravity (SG) been taken into consideration.

RESULTS:
We included 10 078 children. The ability to rule in UTI (as measured by the positive likelihood ratio [LR]) was similar in dilute and concentrated urine for the leukocyte esterase test (11.76 vs 10.71, respectively). The positive LR for urine white blood cell count per high-powered field was higher in dilute urine (9.83 vs 6.12). In contrast, the positive LR for the nitrite test was lower in dilute urine (20.54 vs 47.44). Despite these differences, we found little change in the number of children treated with antibiotics in predictive models that took urine SG into consideration.

CONCLUSIONS:
Although we found that urine SG influences the accuracy of some components of the urinalysis, its inclusion in the decision-making process had negligible effect on the clinical care of children with UTI.
“The Curious Impertinent” and <em>The Second Maiden’s Tragedy</em>: (Self)Subversive Discourses on Gender and Power
Authors: Serrano González Raquel 
Published: October 2019

This paper provides a comparative analysis of “The Curious Impertinent”, an interpolated novel in Don Quixote (1605), and The Second Maiden’s Tragedy, a play attributed to Thomas Middleton premiered in 1611. Cervantes’s story about the stratagem contrived by a jealous husband who persuades his closest friend to test his wife’s fidelity and the pernicious consequences that ensue is rewritten in the subplot of Middleton’s work and adapted to the Jacobean political and ideological context. The play’s main storyline also mirrors the Cervantine-inspired episode: the female protagonist is equally tempted by a tyrant, but, as opposed to the seduced wife, she resists stoically and gives up her life to prevent an otherwise unavoidable rape. Critics of both works are divided as to whether they uphold the dominant construction of women as ‘naturally’ inferior to men, both being permeated by a blatantly misogynistic language that perpetuates the ‘weaker vessels’ ideology. The analysis developed in this paper aims to prove that, even though each text was produced in a different social context –and hence has different political motivations–, both are self-subversive, as they undermine the dominant ideology of femininity and the consequent power hierarchy, in both the private and the public spheres.
INTERNATIONAL FIELD PRACTICE (PPL): PROBLEMS, IMPLEMENTATION, AND COMMUNITY RESPONSES
Authors: Saehu Andang , Putri Hani Hartiani , Nabila Dewi Putri , Nurhapitudin Irman 
Published: October 2019

Abstrak This paper is an evaluative study to explore and analyze the process of implementing the International PPL, the problems encountered in the implementation of International PPL, and the community responses to the implementation of International PPL. In working with the implementation, International PPL was conducted in three steps: pre-field research activities, whilst field research activities, and post-field research activities. Some internal and external problems faced in the implementation of this International PPL. The responses to the International PPL implementation were gained from both internal and external communities.
Internalisasi Nilai-Nilai Akhlaqul Karimah dalam Kehidupan Sehari-hari Siswa SD Negeri 1 Cibugel
Authors: Syahfitra Aidil , Asro Muhammad 
Published: October 2019

Pendidikan dapat diartikan sebagai sebuah bentuk untuk memajukan kehidupan negara, kesejahteraan negara, dan menjadikan negara yang bermoral tinggi, beretika, dan berbudaya sosial yang mulia. Pendidikan dilakukan demi berkembangnya potensi peserta didik agar menjadi manusia yang beriman dan bertakwa kepada Tuhan Yang Maha Esa, berakhlak mulia, sehat, berilmu, cakap, kreatif, mandiri, dan menjadi warga negara yang demokratis serta bertanggung jawab. Pengabdian ini merupakan pengandian dalam bentuk penelitian kualitatif deskriptif, data-data diperoleh melalui observasi, wawancara, dokumentasi, dan sosialisasi . Analisis data menggunakan reduksi data, untuk mendeskripsikan Internalisasi Nilai-Nilai Akhlaqul Karimah dalam Kehidupan Sehari-hari Siswa SD Negeri 1 Cibugel Desa Jayamekar Kecamatan Cibugel Kabupaten Sumedang. Penelitian ini bertujuan untuk memberikan pemahaman kepada siswa akan pentingnya akhlakuk karimah dalam kehidupan sehari-hari baik akhlak kepada Allah, orang tua, guru, teman sebaya maupun akhlak-akhlak yang berkaitan dengan kehidupan sehari-hari. Selain itu juga pengabdian ini juga bertujuan untuk menganalisa bagaimana tingkat moralitas siswa sebagai bahan pertimbangan untuk menilai kualitas akhlak generasi-generasi penerus bangsa, baik itu di masa sekarang atau nanti di masa yang akan datang. Hasil penelitian ini menunjukkan bahwa siswa memiliki antusias dan partisipasi yang tinggi menjadi insan yang lebih baik hal ini terbukti secara implisit dalam kegiatan sosialisasi yang telah dilaksanakan, yang mana hal ini secara tersirat menunjukkan perkembangan akhlak siswa dalam menghargai orang lain.
Tumor Mutational Burden as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors: A Review of Current Evidence
Authors: Klempner Samuel J. , Fabrizio David , Bane Shalmali , Reinhart Marcia , Peoples Tim , Ali Siraj M. , Sokol Ethan S. , Frampton Garrett , Schrock Alexa B. , Anhorn Rachel , Reddy Prasanth 
Published: October 2019

AbstractTreatment with immune checkpoint inhibitors (ICPIs) extends survival in a proportion of patients across multiple cancers. Tumor mutational burden (TMB)—the number of somatic mutations per DNA megabase (Mb)—has emerged as a proxy for neoantigen burden that is an independent biomarker associated with ICPI outcomes. Based on findings from recent studies, TMB can be reliably estimated using validated algorithms from next-generation sequencing assays that interrogate a sufficiently large subset of the exome as an alternative to whole-exome sequencing. Biological processes contributing to elevated TMB can result from exposure to cigarette smoke and ultraviolet radiation, from deleterious mutations in mismatch repair leading to microsatellite instability, or from mutations in the DNA repair machinery. A variety of clinical studies have shown that patients with higher TMB experience longer survival and greater response rates following treatment with ICPIs compared with those who have lower TMB levels; this includes a prospective randomized clinical trial that found a TMB threshold of ≥10 mutations per Mb to be predictive of longer progression-free survival in patients with non-small cell lung cancer. Multiple trials are underway to validate the predictive values of TMB across cancer types and in patients treated with other immunotherapies. Here we review the rationale, algorithm development methodology, and existing clinical data supporting the use of TMB as a predictive biomarker for treatment with ICPIs. We discuss emerging roles for TMB and its potential future value for stratifying patients according to their likelihood of ICPI treatment response.
Surgery Versus Surveillance for Well-Differentiated, Nonfunctional Pancreatic Neuroendocrine Tumors: An 11-Year Analysis of the National Cancer Database
Authors: Assi Hussein A. , Mukherjee Sarbajit , Kunz Pamela L. , Machiorlatti Michael , Vesely Sara , Pareek Vipul , Hatoum Hassan 
Published: October 2019

Abstract

Background
Pancreatic neuroendocrine tumors (panNETs) are a rare group of tumors that make up 2%–3% of pancreatic tumors. Recommended treatment for panNETs generally consists of resection for symptomatic or large asymptomatic tumors; however, optimal management for localized disease is still controversial, with conflicting recommendations in established guidelines. Our study aim is to compare surgical intervention versus active surveillance in nonmetastatic panNETs by size of primary tumor.

Materials and Methods
Using the National Cancer Database, we identified 2,004 patients diagnosed with localized well-differentiated, nonfunctional panNETs (NF-panNETs) between 2004 and 2015. Patients’ clinicopathologic characteristics, treatment modalities, and overall survival (OS) were analyzed using frequency statistics, chi-square, and Kaplan-Meier curves. The objective of the study is to assess the outcome of surgical resection versus nonoperative management in patients with panNETs with different tumor sizes.

Results
Tumor sizes were divided into three categories: &lt;1 cm, 1–2 cm, and &gt;2 cm. The number of patients with tumor size &lt;1 cm, 1–2 cm, and &gt;2 cm was 220 (11%), 794 (39.6%), and 990 (49.4%), respectively. Overall, 1,781 underwent surgical resection, whereas 223 patients did not. Median follow-up was 25.9 months. After adjusting for covariates, surgical resection was associated with improved OS in patients with tumor size 1–2 cm (hazard ratio [HR] = 0.37) and &gt;2c m (HR = 0.30) but not &lt;1 cm (HR = 2.81). Independent prognostic factors were age at diagnosis, Charlson-Deyo comorbidity score, stage, tumor location, and surgical resection. Higher tumor grade was not associated with worse OS.

Conclusion
Our findings suggest that active surveillance is potentially a safe approach for NF-panNETs &lt;1 cm. Larger tumors likely need active intervention. Intermediate-grade tumors did not result in worse survival outcome compared with low-grade tumors. Future studies might consider prospective randomized clinical trials to validate our findings.