bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uncovering Natural Longevity Alleles from Intercrossed Pools of Aging Fission Yeast Cells
Authors: Ellis David A , Mustonen Ville , Rodríguez-López María , Rallis Charalampos , Malecki Michał , Jeffares Daniel C , Bähler Jürg 
Published: August 2018

AbstractChronological lifespan of non-dividing yeast cells is a quantitative trait that reflects cellular aging. By monitoring allele frequencies in aging segregant pools, Ellis et al. uncover regulatory variants in the 5'-untranslated regions of two genes...Quantitative traits often show large variation caused by multiple genetic factors . One such trait is the chronological lifespan of non-dividing yeast cells, serving as a model for cellular aging. Screens for genetic factors involved in aging typically assay mutants of protein-coding genes. To identify natural genetic variants contributing to cellular aging, we exploited two strains of the fission yeast, Schizosaccharomyces pombe, that differ in chronological lifespan. We generated segregant pools from these strains and subjected them to advanced intercrossing over multiple generations to break up linkage groups. We chronologically aged the intercrossed segregant pool, followed by genome sequencing at different times to detect genetic variants that became reproducibly enriched as a function of age. A region on Chromosome II showed strong positive selection during aging. Based on expected functions, two candidate variants from this region in the long-lived strain were most promising to be causal: small insertions and deletions in the 5′-untranslated regions of ppk31 and SPBC409.08. Ppk31 is an ortholog of Rim15, a conserved kinase controlling cell proliferation in response to nutrients, while SPBC409.08 is a predicted spermine transmembrane transporter. Both Rim15 and the spermine-precursor, spermidine, are implicated in aging as they are involved in autophagy-dependent lifespan extension. Single and double allele replacement suggests that both variants, alone or combined, have subtle effects on cellular longevity. Furthermore, deletion mutants of both ppk31 and SPBC409.08 rescued growth defects caused by spermidine. We propose that Ppk31 and SPBC409.08 may function together to modulate lifespan, thus linking Rim15/Ppk31 with spermidine metabolism.
YENİLENEBİLİR ENERJİDE KAMU POLİTİKALARI VE TÜRKİYE
Authors: BERKSOY Turgay , AKBAŞ AKDOĞAN Dilek 
Published: August 2018

Enerji talebinin fosil kökenli enerji kaynakları ile karşılanmasının çevre üzerindeki olumsuz etkileri günümüzde ciddi boyutlara ulaşmıştır. Fosil yakıtların yoğun bir şekilde kullanılması bir yandan küresel ısınma ve iklim değişimi gibi önemli çevresel sorunlara neden olurken diğer yandan da enerji arz güvenliği problemine sebep olmaktadır. Bu bağlamda dünyanın ekolojik dengesinin korunması ve enerji güvenliğinin sağlanması için birçok devlet yenilenebilir enerji kaynaklarına yönelmiştir.
Bu çalışmanın amacı, yenilenebilir enerji kaynaklarının geliştirilmesi ve kullanımının yaygınlaştırılması için yürütülen kamu politikalarını ve bu kapsamda uygulanan teşvik ve destek mekanizmalarını sistematik bir şekilde incelemek ve bu mekanizmaların etkilerini ve etkinliğini değerlendirmektir. Çalışmada Türkiye’nin yenilenebilir enerji politikası ve Türkiye’de politika aracı olarak kullanılan teşvik mekanizmaları açıklanmıştır. Çalışmanın ampirik kısmında teşvik mekanizmaları ile yenilenebilir enerji arasındaki ilişki panel veri teknikleri kullanılarak analiz edilmiştir. Çalışmada, 28 Avrupa Birliği üyesi ülke ile Türkiye için 1990-2015 yılları arası yıllık veriler kullanılmıştır. Sabit fiyat garantisi, kota yükümlüğü, ihale sistemi ve vergisel teşvikler olmak üzere dört teşvik mekanizması modele dahil edilmiştir. Ampirik sonuçlara göre, sadece sabit fiyat garantisi ve kota yükümlüğü teşvik mekanizmaları yenilenebilir enerji üzerinde anlamlı ve pozitif bir etkiye sahiptir. Bu iki teşvik mekanizmalarından herhangi birinden gerçekleşecek bir artış yenilenebilir enerjide de bir artışa neden olacaktır.
Implementación de los sistemas de planificación de recursos empresariales (ERP) en las organizaciones desde la coevolución
Authors: Rivera Silva Andres Camilo , Vargas Reyes Rafael Esteban , Bohórquez Arevalo Luz Esperanza 
Published: August 2018

Introducción: el artículo de revisión bibliográfica es producto de la investigación “Implementación de los sistemas de planificación de recursos empresariales (ERP) en las organizaciones desde la coevolución”, realizada durante el 2016 y el 2017 en la Facultad de Ingeniería Industrial de la Universidad Distrital Francisco José de Caldas.Problema: según diversas investigaciones, las implementaciones de ERP han resultado fallidas y generan pérdidas empresariales.Objetivo: diseñar una propuesta de estudio para que la implementación de ERP resulte exitosa en las organizaciones.Metodología: se inicia por revisar la literatura relacionada con implementación de ERP en las organizaciones e identificar que el 70 % de las empresas no obtuvieron los resultados esperados. Se plantea que la adopción de ERP se puede comprender como un proceso coevolutivo basado en la interacción entre los empleados a través de redes de afiliación formales e informales.Resultados: se propone iniciar por la identificación de las personas que tienen mayor potencial de influir sobre las demás, de manera que se inicie un proceso de propalación de información que circula desde los nodos más influyentes hacia aquellos con los que interactúan.Conclusión: la comprensión del cambio como proceso de coevolución en redes formales e informales da pie a la opción de discutir y repensar la forma en que están organizadas las empresas.Originalidad: hasta el momento no se ha abordado la implementación de este tipo de plataformas desde este punto de vista.Limitaciones: la propuesta se encuentra en fase conceptual, sin embargo, aún no se cuenta con investigación empírica que permita su validación.
Adequação calórico-proteica de pacientes internados em uma unidade de terapia intensiva
Authors: Fischer Maiara De Queiroz , Tatsch Carina Garcia , Faber Jaqueline , Silveira Taismara , Poll Fabiana Assmann 
Published: August 2018

RESUMO
Justificativa e Objetivo: A Terapia Nutricional Enteral (TNE) é utilizada para a manutenção ou recuperação do estado nutricional nos indivíduos com o trato gastrintestinal funcionante, com a ingestão oral parcial ou totalmente comprometida. O objetivo deste estudo foi avaliar o uso de TNE exclusiva, em relação ao que é prescrito e ao que é administrado em pacientes internados em uma Unidade de Terapia Intensiva (UTI) de um Hospital de Ensino do interior do Rio Grande do Sul. Métodos: Trata-se de um estudo de coorte, prospectivo, em que foram incluídos 25 pacientes com idade ≥18 anos, que estavam em TNE exclusiva por período ≥72 horas. A coleta de dados foi realizada entre setembro a dezembro de 2017. Os dados coletados foram registrados no formulário do Serviço de Nutrição e o acompanhamento foi realizado até a alta da unidade ou óbito ou descontinuação da TNE exclusiva. Considerou-se, como adequada a administração energética e proteica ≥ 80% das necessidades. Utilizou-se o SPSS versão 20.0 para analisar as medidas descritivas e foi testada a Correlação de Spearman. Resultados: Dos pacientes avaliados, 52,0% apresentavam sobrepeso, 28,0% apresentavam doença pulmonar, 92,0% iniciaram com a nutrição precoce em até 48 horas, 68,0% tiveram alta domiciliar e 20,0% apresentaram vômito ou diarreia. Observamos que a adequação do valor calórico ficou 88,25% ± 2,55, semelhante a adequação de proteína 88,49% ± 2,51. Conclusão: A maioria dos pacientes receberam fórmula hipercalórica, com uma adequação entre as calorias e a proteína prescrita e administrada superior ao esperado pelo presente estudo.
PENGARUH POLA ASUH ORANG TUA DAN SIKAP BAHASA TERHADAP KEMAMPUAN MEMBACA PEMAHAMAN
Authors: Santosa Arif Ismail , Rafli Zainal , Lustyantie Ninuk 
Published: August 2018

This study is aimed to determine: (1) the influence of parenting style and language attitudes toward the reading comprehension achievement simultaneously; (2) the influence of parenting style and language attitude toward the reading comprehesion achievement respectively. This research applied a quantitative approach with descriptive method. The data collection used questionnaires and objective tests. Questionnaires were used to collect the data on parenting style and language attitudes, and the objective tests were used to collect the data of reading comprehension achievement. The samples of this study were 69 people, and the analysis of this study used descriptive statistic namely regression analysis technique. The result of the research showed: (1) there was positive and significant influence of parenting style and language attitude toward reading comprehension achievement of the grade VII students of The State Junior High School 177 Jakarta about 85.5%; (2) there was a positive and significant influence of parenting style toward the reading comprehension achievement about 38.7%, and language attitudes towards reading comprehension achievement was about 10.2%.
Penentuan Karakteristik Tremor Gunungapi Semeru Jawa Timur Berdasarkan Analisis Spektral (Studi Kasus: Oktober 2015-Desember 2015)
Authors: Municha Dea Hertiara , Iryanti Mimin , Triastuty Hetty 
Published: August 2018

Gunungapi Semeru merupakan salah satu gunung aktif di Indonesia dengan tipe erupsi vulkanian dan strombolian. Penelitian ini menggunakan data seismik digital G. Semeru yang terekam pada bulan Oktober 2015- Desember 2015. Data yang akan digunakan dalam penelitian ini yaitu data tremor vulkanik gunungapi Semeru. Penelitian ini bertujuan untuk mengetahui perubahan aktivitas vulkanik yang berdasarkan pada perubahan kegiatan tremor vulkanik. Tremor vulkanik merupakan gempa yang sering terjadi di sekitar gunungapi, gempa ini terjadi akibat aktivitas pergerakan magma ke atas di dalam gunungapi. Salah satu cara untuk mengetahui karakteristik aktivitas Gunung Semeru yaitu dengan analisis spektral. Analisis spektral ini dilakukan dengan menerapkan Fast Fourier Transform. Tujuan dari transformasi ini adalah untuk merubah sinyal dari domain waktu ke domain frekuensi sehinggal diperoleh spektrum frekuensi dari sinyal-sinyal vulkanik. Berdasarkan analisis spektral pada gunung Semeru ini didominasi tremor harmonik yang memiliki ciri-ciri bentuk sinyal puncak spektral yang teratur serta memiliki frekuensi dasar tremor harmonik berkisar 0.1 Hz-2 Hz, sedangkan frekuensi dominan tremor harmonik berkisar 0.2 Hz-3.5 Hz, serta kandungan frekuensi tremor G. Semeru tergolong rendah. Serta terjadi perubahan tertinggi frekuensi dasar dan frekuensi dominan pada stasiun Puncak.
Reorganização Curricular da Escola Estadual Heronides Araújo: Articulação Entre o Ensino Médio e a Educação Profissionalizante
Authors: Almeida Laura Isabel Marques Vasconcelos de , Ferreira Camila Rodrigues Viana , Gama Marta Maria 
Published: August 2018

Este artigo tem como objetivo analisar a articulação das práticas pedagógicas decorrentes da Matriz Curricular Nacional para o Ensino Médio da Escola Estadual Heronides Araújo e sua articulação com o Centro de Educação Profissional e Tecnológica – CEPROTEC. O embasamento dessa articulação é a Lei de Diretrizes e Bases da Educação (LDB) nº. 9394/96 e as Diretrizes Curriculares Nacionais do Ensino Médio, desenvolvido por meio da pesquisa de campo, com abordagem metodológica qualitativa. O estudo aponta que apesar da possibilidade de integração entre a formação básica do estudante e a formação profissionalizante, a política de educação profissional ainda processa-se mediante programas focais e contingentes numa travessia marcada por intensos conflitos e no terreno da contradição.Palavras-chave: Educação Profissionalizante. Ensino Médio. Práticas Pedagógicas. Escola Estadual Heronides Araújo.AbstractThis article aims to analyze the articulation of pedagogical practices arising out of the National Curricular Matrix for High school of Heronides Araújo State School and its articulation with the Center of Vocational and Technological Education - CEPROTEC. The basis of this articulation is the Education Guidelines and Bases Law (LDB) number 9394/96 and the National Curricular Guidelines of the High School education, developed by means of field research, with a qualitative methodological approach. The study points out that despite the possibility of integration between the student’s basic formation and the vocational training policy, vocational education is still processed through focal and uncertain programs in a journey marked by intense conflict and on the ground of contradiction.Keywords: Vocational Education. High School. Pedagogical Practices. Heronides Araújo State School.
Uso de Plataformas Integradoras de Ferramentas Tecnológicas e Pedagógicas em Ambiente Virtual de Aprendizagem em Profissões de Saúde
Authors: D'Alpino Paulo Henrique Perlatti , Polassi Mackeler Ramos , Maia Marcelo Henrick Matochek , Tomaz Pedro Luiz Santos , Oliveira Thales De Sá 
Published: August 2018

A contínua busca por conhecimento faz parte da sociedade contemporânea, profissionais e estudantes buscam uma melhor qualidade de vida baseada em sua qualificação profissional e melhores salários. Por outro lado, para se alcançar melhor qualificação, de acordo com a realidade individual, se exige disponibilidade de tempo, investimento financeiro e motivação para ingressar em uma instituição de Ensino Superior. Este artigo objetiva fornecer uma visão geral da diversidade de ferramentas disponíveis para o aprendizado e identificar as diretrizes para pesquisas futuras relacionadas aos métodos de ensino e aprendizagem em profissões da área de saúde, com ênfase em Odontologia. Após uma introdução e definições dos diferentes métodos de aprendizagem, este artigo considera a importância de identificar os desafios das diferentes formas de aprendizado na área da saúde, quer seja híbrido (blended learning) ou totalmente on-line, bem como as diferentes formas de avaliação destes métodos de ensino. É fato que a maior crítica ao ensino a distância recai sobre a falta de contato pessoal com os pacientes e a necessidade de se estabelecer vínculo. Conclui-se que os métodos de ensino a distância, em que pesem as limitações que se impõem, é promissor nos cursos da área de saúde, o que certamente inclui a Odontologia.Palavras-chave: Ensino a Distância. Ensino Semipresencial. OdontologiaAbstractThe continuous search for knowledge is part of contemporary society, and professionals and students seek for a better quality of life based on their professional qualification and better incomes. On the other hand, to obtain a better qualification according to the individual reality of each subject requires the availability of time, financial investment, and motivation to enter a higher education institution. This article aims to provide an overview of the diversity of available learning tools and to identify the guidelines for future research related to teaching and learning methods in health professions, with emphasis in Dentistry. After an introduction and definitions of the different learning methods, this article considers the importance of identifying the challenges of the different learning forms in the area of health, whether it is hybrid (blended learning) or online, as well as the different forms of evaluation of these teaching methods. It is a fact that the greatest criticism of distance education lies in the lack of personal contact with patients and the need to establish a link. As a conclusion, in spite of the limitations imposed, methods of distance education are promising in the health care courses, which certainly may include Dentistry.Keywords: E-Learning. Blended Learning. Dentistry
O Fisioterapeuta como Membro da Equipe Multidisciplinar no Pronto Socorro
Authors: Mastroantonio Emmanuel Musetti , Morais Júnior Sérgio Luis Alves de , Morais Júnior Sérgio Luis Alves de 
Published: August 2018

Fisioterapia pode ser definida como a ciência da saúde que estuda, previne e trata os distúrbios funcionais. Pronto Socorro é um setor do serviço de saúde hospitalar de atenção secundária e, geralmente, a porta de entrada do hospital, por onde adentram vários tipos de pacientes que podem ser classificados como Urgência e/ou Emergência, e com isso, apresentam maior risco de morte. O objetivo deste estudo foi apresentar as principais funções do fisioterapeuta e a importância do mesmo na equipe multidisciplinar em urgência e emergência no pronto socorro. Neste estudo se discorreu sobre os perfis de pronto socorro com indicadores em saúde, utilização dos serviços de urgência e suas causas de procura, além da função do fisioterapeuta como membro da equipe multidisciplinar, bem como a legislação vigente acerca da temática. A inserção do profissional nas unidades é recente, e são escassas as pesquisas envolvendo este novo campo, assim, se propõem maiores estudos para avaliar o impacto da atuação do profissional no setor, e ser de extrema importância que os profissionais que irão atuar neste novo campo busquem atualização em virtude da área compreendida.Palavras-chave: Fisioterapia. Serviço Hospitalar de Fisioterapia. Socorro de Urgência.AbstractPhysiotherapy can be defined as the health science that studies, prevents and treats functional disorders. Emergency room is a sector of hospital health, service of secondary care and generally at the hospital entryway, where various types of patients come in who can be classified a stateof urgency or emergency and run imminent death risk. The purpose of this study was to present the main activities of the physiotherapist and the his or her importance in the multidisciplinary team in emergency care in the emergency room. In this study, it was talked about the emergency room profiles with health indicators, use of emergency services and the causes why patients look for it, besides the physiotherapist’s role as a member of the multidisciplinary team, as well as the current legislation on the subject. The professional insertion in the units is recent, and the studies are insufficient involving this new field, thus it is proposed further studies to evaluate the professional practice impact in the industry, and is of unmost importance that the professionals who will work in this new field to catch up on due to the area that he or she is inserted to..Keywords: Physical Therapy Specialty. Physical Therapy Department, Hospital. Emergency Relief.
Implications of TTIP and TPP on Bangladesh and Nepal
Authors: Al Amin Mohammed Nafeez 
Published: August 2018

The Transatlantic Trade and Investment Partnership (TTIP) and the Transpacific Partnership (TPP) could the biggest trade deal in the history. The EU and the USA are in the process of, or contemplating, to sign Free Trade Agreements (FTAs) under TTIP and TPP. As, the European Union (EU) and the USA are the biggest trading partner of all the South Asian countries, such preferential tariff arrangements could lead to significant erosion of preferences enjoyed currently by the South Asian Developing Countries such as, Bangladesh and Nepal. In this backdrop, the main objective of the present study is to investigate the potential economic impacts of tariff eliminations under TPP and TTIP on various macro and trade variables of Bangladesh and Nepal. In this context, a standard computable general equilibrium (CGE) analysis has been adopted by using the Global Trade Analysis Project (GTAP) model and database to explore the aggregate impact as well as sectoral implications. The analysis evinces that complete integration in terms of tariff elimination under these two mega deals, Bangladesh and Nepal could face tremendous negative impact on their economy. The analysis also suggests that Bangladesh and Nepal may consider joining to the TPP to minimize the negative economic impact due to the mentioned deals.

JEL Classification Code: F14, F15, F17
The Growth Explains its Reasons Itself: From the Retrospect of Bangladesh Economy
Authors: Akter Farzana , Rahman A.S.M. Habibur 
Published: August 2018

Bangladesh, a country with a potential economic growth had a rich agro-based economy before & after its independence. Being one of the most heavily populated countries of the world, it had to face several development challenges. Accelerated growth was just a demand of time that was pushing the whole economy towards Industrial & Service Sector where growth could be achieved swiftly. This research was performed to portray the structural transition in the economy of Bangladesh after independence. GDP at a constant price was used to represent The Growth of the economy. Step by step, the decomposition method was used to split GDP to the bottom & to get the most influential sectors & sub-sectors and their recent trends. The findings from decomposition method were supported by linear regression. A detail & authentic dataset (42 years) was used to clarify the transition to the economy.
JEL Classification Code: O14, O53
Factors Affecting the Financial Performance of Property Andreal Estate Companies Listed at Indonesia Stock Exchange
Authors: Deitiana Tita , Habibuw Lionel Greg 
Published: August 2018

Financial performance is one of the factors used by investors in buying shares. For companies, improving financial performance is a must in order to keep the company's stock attractive to investors. Financial statements published by the company are a reflection of the company's financial performance. These financial statements are the result of the accounting process that is intended to provide the financial information of a company. The financial information can be used by users for making investment decisions.
Performance is the result of the fulfillment of the tasks assigned. Company performance describes how individualsin the company tries to achieve a goal. Company performance illustrates the magnitude of the results in a process that has been achieved compared with the company’s goal. The purpose of this study is to find out factors determining financial performance.
The objects of this study are property and real estate companies listed on the Indonesia Stock Exchange (IDX) during the period of 2007 – 2012. Data for this study stems from secondary data gathered by analyzing financial statement of the sample companies. The data is then analyzed with Eviews 7.2 Panel Data Regression Analysis.
The research findings can be summarized as follows. Variable leverage and Firm Age has an effect on financial performance. Other variables like liquidity, Firm Size, Managerial Ownership and Block holder Ownership have no effect on financial performance.
JEL Classification code: G31