bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early Life Stress in Adolescent Migraine and the Mediational Influence of Symptoms of Depression and Anxiety in a Canadian Cohort
Authors: Hammond Nicole G. , Orr Serena L. , Colman Ian 
Published: September 2019

ObjectiveThis study sought to examine the association between early life stressors and adolescent headache in the Canadian population, and the potential mediating influence of symptoms of depression and anxiety.BackgroundEarly life stress or adverse childhood experiences have a well‐documented association with migraine and headache in adulthood, as do symptoms of depression and anxiety. However, there is limited evidence examining the relationship between early life environmental stressors and adolescent headache, and a lack of longitudinal research. Family‐level factors including parenting behaviors and parental influences such as maternal distress have been implicated in pediatric chronic pain.MethodsThis study used data from 2313 respondents of the National Longitudinal Survey of Children and Youth, followed prospectively from age 0 to 1 years at baseline (1994/1995) until age 14 to 15 years (2008/2009). The relationships between 4 measures of early life family level stressors, and outcomes of incident health professional‐diagnosed migraine and self‐reported, unclassified frequent headache (>1 per week) were examined. We conducted a series of mediation analyses of the indirect effect (IE) of family‐level stressors on headache outcomes through symptoms of depression and anxiety in late childhood. The IE and 95% bias‐corrected confidence interval (CIBC) were estimated using maximum likelihood logistic regression methods (log odds scale).ResultsThe proportion of respondents with incident migraine and frequent headache was 3.1% and 11.1%, respectively. There were no direct associations between distal early life family‐level factors and adolescent headache. Symptoms of depression‐ and anxiety‐mediated relationships between family dysfunction (IE 0.0181, 95% CIBC 0.0001‐0.0570), punitive parenting (IE 0.0241, 95% CIBC 0.0015‐0.0633), parental depressive symptomatology (IE 0.0416, 95% CIBC 0.0017‐0.0861), and incident migraine but not frequent headache. Indirectly, presence of family dysfunction, punitive parenting, and higher parental depressive symptomatology in early life were associated with a greater likelihood of migraine in adolescence, through greater symptoms of depression and anxiety in late childhood.ConclusionsFindings provide support for the influence of early life family‐level factors on prospective risk of developing migraine, through symptoms of depression and anxiety. Addressing family dynamics in clinical practice may reduce unnecessary stress‐related burdens on children and adolescents, which could lead to improvements in their somatic complaints.
Timing and development of sedimentation of the Cleaverville Formation and a post‐accretion pull‐apart system in the Cleaverville area, coastal Pilbara Terrane, Pilbara, Western Australia
Authors: Kiyokawa Shoichi , Aihara Yuhei , Takehara Mami , Horie Kenji 
Published: September 2019

AbstractIn the Cleaverville area of Western Australia, the Regal, Dixon Island, and Cleaverville Formations preserve a Mesoarchean lower‐greenschist‐facies volcano‐sedimentary succession in the coastal Pilbara Terrane. These formations are distributed in a rhomboidal‐shaped area and are unconformably overlain by two narrowly distributed shallow‐marine sedimentary sequences: the Sixty‐Six Hill and Forty‐Four Hill Members of the Lizard Hills Formation. The former member is preserved within the core of the Cleaverville Syncline and the latter formed along the northeast‐trending Eighty‐Seven Fault. Based on the metamorphic grade and structures, two deformation events are recognized: D1 resulted in folding caused by a collisional event, and D2 resulted in regional sinistral strike‐slip deformation. A previous study reported that the Cleaverville Formation was deposited at 3020 Ma, after the Prinsep Orogeny (3070–3050 Ma). Our SHRIMP U–Pb zircon ages show that: (i) graded volcaniclastic–felsic tuff within the black shale sequence below the banded iron formation in the Cleaverville Formation yields an age of (3 114 ±14) Ma; (ii) the youngest zircons in sandstones of the Sixty‐Six Hill Member, which unconformably overlies pillow basalt of the Regal Formation, yield ages of 3090–3060 Ma; and (iii) zircons in sandstones of the Forty‐Four Hill Member show two age peaks at 3270 Ma and 3020 Ma. In this way, the Cleaverville Formation was deposited at 3114–3060 Ma and was deformed at 3070–3050 Ma (D1). Depositional age of the Cleaverville Formation is at least 40–90 Myr older than that proposed in previous studies and pre‐dates the Prinsep Orogeny (3070–3050 Ma). After 3020 Ma, D2 resulted in the formation of a regional strike‐slip pull‐apart basin in the Cleaverville area. The lower‐greenschist‐facies volcano‐sedimentary rocks are distributed only within this basin structure. This strike‐slip deformation was synchronous with crustal‐scale sinistral shear deformation (3000–2930 Ma) in the Pilbara region.
American cutaneous leishmaniasis in French Guiana: an epidemiological update and study of environmental risk factors
Authors: Loiseau Rémi , Nabet Cecile , Simon Stephane , Ginouves Marine , Brousse Paul , Blanchet Denis , Demar Magalie , Couppie Pierre , Blaizot Romain 
Published: September 2019

AbstractBackgroundAmerican cutaneous leishmaniasis (ACL) is endemic in French Guiana. Its epidemiology is evolving, notably because of immigration, anthropization of natural areas, and new microbiological methods. Our first objective was to update epidemiological data. Our second objective was to look for risk factors of ACL.MethodsThis multicentric study was conducted from October 2017 to June 2018 in French Guiana. Patients with suspicion of mucocutaneous leishmaniasis were included in case of positive smear, culture, or PCR‐RFLP on skin biopsy.ResultsOne hundred and twenty‐three patients met the inclusion criteria. Among those patients, 59.3% were Brazilian, mostly gold miners. Most of them (58%) were between 16 and 40 years old, and 69% were male. A large proportion of patients lived in traditional wooden houses (51%). Patients living in coastal towns were usually infected during trips to the primary forest (60%) and had a shorter time to diagnosis than workers of the hinterland. Among environmental risk factors, the presence of a water spring (40%) and dogs around houses (40%) were frequently reported. Leishmania guyanensis represented 80% of cases, followed by Leishmania braziliensis (6%), Leishmania naiffi (2%), and Leishmania amazonensis (1%).ConclusionsGold mining and trips to the primary forest represent high‐risk situations for ACL in French Guiana, where the population of infected patients is dominated by Brazilian immigrants. Possible environmental risk factors such as the presence of dogs, water sources, and traditional wooden houses require further investigation.
Mediating role of self‐efficacy in the relationship between family social support and hypertension self‐care behaviours: A cross‐sectional study of Saudi men with hypertension
Authors: Bahari Ghareeb , Scafide Katherine , Krall Jenna , Mallinson R. Kevin , Weinstein Ali A. 
Published: September 2019

AbstractBackgroundSelf‐efficacy and family social support are significantly associated with hypertension self‐care behaviours. However, little is known about their mechanism in Saudi Arabia. This cross‐sectional study aimed to examine the relationships among family social support, self‐efficacy, and self‐care behaviours among men with hypertension in Saudi Arabia.MethodsData were collected from May to August of 2018. The Hypertension Self‐Care Profile and the Perceived Social Support from Friends and Family scales were used to measure the study variables. Multiple linear regression was used to analyse the relationships between the variables, and the Baron and Kenny test was used to assess if self‐efficacy mediated the relationship between family social support and hypertension self‐care behaviours.ResultsRespondents (N = 158) from the Jizan and Al‐Sharqia regions of Saudi Arabia completed the survey. Family social support and self‐efficacy were significantly associated with hypertension self‐care behaviours. In regression, self‐efficacy was the only variable significantly associated with hypertension self‐care behaviours. Self‐efficacy fully mediated the relationship between family social support and hypertension self‐care behaviours.ConclusionsInterventions to enhance hypertension self‐care behaviours among Saudi men could focus on increasing individual's self‐confidence to perform specific healthy behaviours. Family support can also contribute to the performance of hypertension self‐care behaviours.
Clinical significance of granulomas in Crohn's disease: A systematic review and meta‐analysis
Authors: Hong Seung Wook , Yoon Hyuk , Shin Cheol Min , Park Young Soo , Kim Nayoung , Lee Dong Ho , Kim Joo Sung 
Published: September 2019

AbstractBackground and AimEpithelioid granuloma is one hallmark used to histologically diagnose Crohn's disease (CD). However, the clinical significance of granulomas in CD is unclear. Therefore, we performed a meta‐analysis to compare the clinical features with CD according to the presence of granulomas.MethodsA literature search in PubMed, EMBASE, and Cochrane databases was performed on manuscripts published until October 2018. We included studies that met the following inclusion criteria: (i) patient: patients with CD; (ii) exposure: granulomas on the pathology; (iii) comparator: no granulomas; and (iv) outcomes: disease location, disease behavior, perianal disease, disease activity, use of biologics, and CD‐associated hospitalization, surgery.ResultsNineteen studies met our inclusion criteria. Granulomas in CD patients were associated with a higher proportion of ileocolonic disease (odds ratio [OR]: 1.49, 95% confidence interval [CI]: 1.21–1.83), a higher proportion of upper gastrointestinal disease (OR: 2.25, 95% CI: 1.28–3.95), a higher proportion of penetrating behavior (OR: 1.48, 95% CI: 1.09–2.01), a higher prevalence of perianal disease (OR: 2.15, 95% CI: 1.48–3.11), and a higher severity index at presentation (standardized mean difference: 0.20, 95% CI: 0.09–0.32). In addition, the use of biologics was significantly higher in CD patients with granulomas compared with without granulomas (OR: 1.66, 95% CI: 1.07–2.59). The presence of granulomas was significantly associated with CD‐associated hospitalization (OR: 3.88, 95% CI: 1.44–10.49), but not with CD‐associated surgery.ConclusionsClinical features in CD patients were significantly different according to the presence of granulomas. It may indicate a more aggressive phenotype of CD.
Clinical spectrum of AIFM1‐associated disease in an Irish family, from mild neuropathy to severe cerebellar ataxia with colour blindness
Authors: Bogdanova‐Mihaylova Petya , Alexander Michael D. , Murphy Raymond P. , Chen Hongying , Healy Daniel G. , Walsh Richard A. , Murphy Sinéad M. 
Published: September 2019

AbstractMutations in apoptosis‐inducing factor mitochondrion‐associated‐1 (AIFM1) cause X‐linked peripheral neuropathy (Cowchock syndrome, CMT4X); however, more recently a cerebellar presentation has been described. We describe a large Irish family with seven affected males. They presented with a variable age of onset, 18 months to 39 years of age. All developed variably present sensorineural deafness, peripheral neuropathy, cerebellar ataxia, and pyramidal involvement. In addition, three had colour vision deficiency. Scale for the assessment and rating of ataxia ranged 2 to 23/40, while Charcot‐Marie‐Tooth neuropathy score 2 varied between 7 and 13/36. All individuals had normal cognitive assessment. Neurophysiology demonstrated length‐dependent large‐fibre sensorimotor axonal neuropathy, with particular involvement of superficial radial sensory responses. Brain imaging, performed in four, revealed varying extent of cerebellar atrophy, and white matter changes in one. Optical coherence tomography was abnormal in one, who had unrelated eye pathology. Four obligate female carriers were assessed clinically, two of them neurophysiologically; all were unaffected. Whole genome sequencing demonstrated a previously reported hemizygous AIFM1 mutation. Analysis for mutations in other genes associated with colour deficiency was negative. AIFM1‐associated phenotype in this family demonstrated significant variability. To our knowledge, this is the first report of AIFM1‐associated colour blindness. Superficial radial nerve was particularly affected neurophysiologically, which could represent a phenotypic marker towards this specific genetic diagnosis.
Combination therapy with salicylic acid chemical peels, glycyrrhizin compound, and vitamin C for Riehl's melanosis
Authors: Wang Lian , Wen Xiang , Hao Dan , Li Yong , Du Dan , Jiang Xian 
Published: September 2019

AbstractBackgroundRiehl's melanosis is a chronic, refractory disorder, which can adversely affect patient's quality of life. Intense pulse light, neodymium‐doped yttrium aluminum garnet laser, hydroquinone, tranexamic acid have been reported to treat this disease, but there have been few reports on the effectiveness of other treatments.AimTo assess the efficacy and safety of triple combination therapy with salicylic acid chemical peels, oral glycyrrhizin compound, and vitamin C for Riehl's melanosis.Patients/MethodsThree patients diagnosed with Riehl's melanosis were enrolled. All patients were treated with glycyrrhizin compound (150 mg/d), vitamin C (100 mg/d), and salicylic acid 30% peels once every 2 weeks. Clinical photographs and VISIA were used to assess the efficacy.ResultsAll patients received obvious improvement and reported no obvious side effects.ConclusionTriple combination therapy with salicylic acid peels, oral glycyrrhizin compound, and vitamin C is a safe and effective modality for Riehl's melanosis.
THERMOGENIC PETROLEUM POTENTIAL OF THE NANKAI SUBDUCTION ZONE, OFFSHORE SW JAPAN
Authors: Shiraishi K. , Yamada Y. , Nibe T. 
Published: September 2019

In the Kumano forearc basin, offshore SW Japan, the potential occurrence of hydrocarbons has been inferred from both geophysical surveys which point to the presence of natural gas hydrates, and geochemical analyses of gas samples recovered from boreholes and submarine mud volcanoes. The forearc basin is located in the inner part of the Nankai Trough where the Philippine Sea plate is subducting northwards beneath SW Japan. The basin succession unconformably overlies a deformed accretionary prism complex. Hydrocarbons with both microbial and thermogenic origins have been recorded in the Kumano Basin, but the thermogenic petroleum potential is poorly constrained because the regional‐scale geological architecture of the Nankai subduction zone is not well understood.In this paper, the regional‐scale petroleum potential of the Nankai Trough is investigated based on the geological interpretation of new seismic reflection images. The images were derived from legacy seismic survey data using advanced processing techniques such as reverse time migration, which make use of both primary and multiple reflections in wide‐angle seismic data collected with ocean‐bottom seismographs. In the study area, a seaward‐dipping reflector was identified which terminates at the plate boundary décollement and which is interpreted as part of the boundary between previously‐identified older (>14 Ma) and younger (<6 Ma) accretionary prisms. A triangle body at the base of the younger accretionary prism is interpreted to consist of underthrusted sediments including thick hemipelagic mudstones with source rock potential which were scraped off the down‐going oceanic plate. These tentatively identified, deeply‐buried mudstones may have the potential to generate thermogenic hydrocarbons which may then migrate upwards along dipping carrier beds or faults and fractures to the unconformity at the base of the Kumano forearc basin succession. The presence of hydrocarbons in the accretionary prism may be inferred from positive amplitude anomalies which have been identified in the reprocessed multi‐channel seismic data.The new reflection interpretations therefore allow the potential for thermogenic petroleum to be proposed in the study area. The hydrocarbon potential at this subduction margin may therefore rely not only on shallow microbial methane, but may also involve deeper, thermogenic petroleum generated within the underlying accretionary prism.
Effect of common and new gums on the quality, physical, and textural properties of bakery products: A review
Authors: Salehi Fakhreddin 
Published: September 2019

AbstractHydrocolloids (gums) have a good functional characteristic such as emulsifying, gelling, solubility, and textural improvement. In the bakery products, hydrocolloids were used to improving dough performance, bread and cake characteristics, sensorial quality, and extension the products shelf life. Several studies reported the potential use of hydrocolloids in breads, biscuits, cakes, and pasta formulation. The present review summarized the effect of the most common and new hydrocolloids (xanthan, guar, Arabic, carrageenan, karaya, alginate, acacia, methylcellulose, carboxy methyl cellulose, hydroxyl propyl methyl cellulose, locust bean, balangu seed, wild sage seed, basil seed, and cress seed gums) on the rheological, physicochemical, textural, and quality characteristics of bakery products. Gums addition improved volume and porosity of the breads and cakes. Gums influence on the gelatinization and retrogradation of starch and decreased the retrogradation of starch. In the bakery products, hydrocolloids were used to improving mixing and increasing the shelf life of the products through moisture preservation and avoidance of syneresis in some frozen foods. This study summarized the influence of the most common and new hydrocolloids on the rheological, physicochemical, textural, and quality characteristics of bakery products. Addition of seeds gum to the breads, biscuits, cakes, and pasta formula led to an increase in the viscosity of the batter. Also, the firmness of bakery products showed that they became softer with increasing gum levels.
Relationship between the frequency of nursing activities and adverse outcomes in patients with acute coronary syndrome: A retrospective cohort study
Authors: Yu Hye Yon , Ahn Eun Kyoung , Seo Eun Ji 
Published: September 2019

AbstractThe aim of this retrospective cohort study was to identify the relationship between the frequency of nursing activities during the first hospitalization and adverse outcomes in patients with acute coronary syndrome by using electronic health records. Patients diagnosed with acute coronary syndrome from April 2010 to April 2015 were examined for eligibility based on 36 months of major adverse cardiac events as the main outcome. Among the 652 patients who were enrolled, 66 patients experienced major adverse cardiac events. The average frequency of nursing activities was 1098.7 (±2703.8), and four variables (length of hospital stay, albumin level, hemoglobin level, and frequency of nursing activities) were significantly associated with 36 months of major adverse cardiac events. After adjusting for these variables, the frequency of nursing activities was found to be the only significant factor associated with the incidence of 36 months of major adverse cardiac events. This finding suggests that patients with acute coronary syndrome who require more frequent nursing activities during the first hospitalization could be vulnerable to adverse outcomes and should be closely monitored.
Unintentional non‐fatal hospitalised falls and motor vehicle injuries in the Auckland and Northland regions: Geographical patterns and associations with rurality
Authors: Zhao Jinfeng , Gulliver Pauline , Exeter Daniel J. , Lee Arier , Browne Michael , Ameratunga Shanthi 
Published: September 2019

AbstractThis paper examined the relationship between rurality and unintentional non‐fatal hospitalisations for falls and motorised vehicle transport injuries and their geographic patterns in New Zealand. Data were constructed from Statistics New Zealand's Integrated Data Infrastructure. Logistic regression revealed that the odds of hospitalisations from falls were lower in more rural areas, but motor vehicle injuries were higher. The odds of injured people being discharged from a ward increased with rurality for both injury types. This study discovered geographical disparities in the two injury types. The findings of this study direct attention to underlying contextual factors that require targeted prevention strategies.
Effects of antidepressant and antipsychotic use on weight gain: A systematic review
Authors: Alonso‐Pedrero Lucia , Bes‐Rastrollo Maira , Marti Amelia 
Published: September 2019

SummaryWeight gain is an adverse effect of antidepressants and antipsychotics. This side effect can lead to numerous comorbidities and reduces life expectancy. The use of these drugs is increasing worldwide, and the weight gain produced by them represents a common clinical challenge. The goal of this systematic review was to evaluate the potential association of antidepressant and antipsychotic therapy with body weight gain in cohort studies. A search of cohort studies investigating the association between weight gain and the use of antidepressants and antipsychotics in individuals was conducted through the PubMed database from 1 January 2008 to 31 January 2019 following the PRISMA statement. We found 27 independent eligible cohort studies that included children (2‐18 years old) and adult (18‐103 years old) subjects. Most of the included studies showed a 5% weight gain in individuals using antidepressant therapy. However, Quetiapine, Haloperidol, Trifluoperazine, Risperidone, Aripiprazole, Olanzapine, and Clozapine increased body weight ≥7% from baseline, which is considered a clinically significant result. Weight loss was found in individuals treated with Bupropion. Further cohort studies with higher sample sizes and longer durations of treatment are needed to confirm our observations.