bluuebunny/crossref_metadata_2025_split huggingface dataset:
SCIENCEPRENEURSHIP MAHASISWA PRODI IPA PADA MATA KULIAH PRAKTIKUM BIOLOGI DASAR
Authors: Fawaida Ulya , Budhi Henry Setya , Zannah Ullum Miftaqul 
Published: September 2019

Pada era yang terus berkembang mahasiswa dituntut berdaya kreatif dan inovatif serta, dapat menciptakan lapangan pekerjaan untuk mengurangi angka pengangguran. Pada penelitian ini dosen berusaha menumbuhkan minat berwirausaha mahasiswa dengan menggunakan pendekatan <em>sciencepreneurship </em>pada mata kuliah Praktikum Biologi Dasar. Metode penelitian ini yaitu menggunakan data kuantitatif yang di prosentasekan kemudian dianalisis dan dinarasikan. Populasi pada penelitian ini mahasisa Tadris IPA kelas A dan kelas B yang datanya diambil secara acak, terdiri dari 25 mahasiswa. Pendekatan sciencepreneurship dapat diterapkan pada materi biotekonologi konvensional yaitu pada pembuatan tempe dan yogurt. Pada pendekatan pembelajaran ini memberikan pengalaman yang bermanfaat diantaranya selalu berpikir positif, bekerja keras dan cerdas, kerjasama tim, berfikir kritis, sikap pantang menyerah, kreatif, membuktikan proses sains dan fakta lapangan serta, menumbuhkan minat menjadi seorang <em>entrepreur.</em>
Microgravity Mapping of an Inception Doline Shaft System
Authors: Hutchinson Peter J. , Balog Alexander , Hoover Shad E. 
Published: September 2019

ABSTRACT
Reactivation of an inception doline shaft system through anthropogenic actions, precipitation, and possibly seismic activity induced subsidence in a hospital emergency room that was under construction in State College, PA. The convergence of Tropical Storm Lee and Hurricane Irene is interpreted to have caused the building's brick edifice to fall and induce vertical shifts in the reinforced concrete entrance floor slab. Microgravity mapping of the existing hospital emergency room entrance; the emergency room building under construction; and the parking lot in front of the emergency room entrance documented the presence of a doline shaft system (i.e., inter-connected sinkhole). Groundwork for the construction of the new emergency room included grading and leveling of the property. Surface water runoff entered the construction site from a parking lot that sloped toward the addition and to a non-functioning stormwater inlet. The grading for the new construction exposed an open fracture for surface runoff. Subsequent channeling of surface water to the conduit provided drainage for surface runoff, but it also initiated subsidence throughout the existing structure and the addition that was under construction. Engineering rehabilitation included a limited mobility (LM) grout program to plug subsoil fracture karren drainage systems and stabilize the surface. Drilling progressed in four stages, initially focusing on areas of greatest subsidence. In total, 60 injection points were completed to a mean depth of 24 m below grade in an area measuring approximately 370 m2. During LM grouting, 867 m3 of a sand-and-cement grout mixture were injected to stabilize the area.
Wellbore Cleanout in Inclined and Horizontal Wellbores: The Effects of Flow Rate, Fluid Rheology, and Solids Density
Authors: Pandya Soham , Ahmed Ramadan , Shah Subhash 
Published: September 2019

Summary
Coiled tubing (CT) is extensively used in wellbore-cleanout operations to remove solid particles such as drilled solids or residual proppant from hydraulic-fracturing treatments. The cleanout operation is often associated with nonproductive time and significantly adds to the operational cost. This study is aimed at developing a model to predict the required fluid-circulation rate and time to efficiently remove solids from the wellbore and optimize the cleanout operation.
To study the hole-cleaning mechanism, solids-bed-erosion experiments were conducted using a flow loop that has a 10.4-m-long annular test section. The effects of solid density, flow rate, inclination angle, and fluid type (Fluids 1, 2, and 3) on the cleanout operation were investigated by measuring bed erosion and hole-cleaning efficiency. During the experiment, a stable bed was initially formed in the annular test section. Then, the bed was eroded and the amount of solids removed was measured to determine cleanout efficiency. In addition, bed height was measured at different locations in the test section as a function of circulation time. The measurements resulted in the generation of a bed-erosion curve (plot of average bed height vs. circulation time) for each test. The erosion curves obtained from this study are consistent with previously reported measurements.
This study indicates that flow velocity, inclination, and fluid rheology are the primary factors in determining hole-cleaning efficiency. Bed erosion is highly prominent at high flow velocities, especially with low-viscosity fluids, because the increase in velocity results in strong turbulence and the lifting of bed particles. Alternatively, an increase in viscosity reduces particle settling and maintains particles in suspension once they enter the flow stream. This is attributed to a greater drag-force generation, which facilitates particle transport by hindering redeposition. However, an increase in viscosity limits the particle-lifting capacity of the fluids by affecting the near-bed velocity profile, which is critical for lifting bed particles. Therefore, it is recommended to use low-viscosity fluids in cleanout operations at high-inclination well sections, and vice versa. Solids density has a moderate (up to 30%) effect on cleanout efficiency compared with fluid velocity and rheology. For different solid densities at a constant flow rate, high-density solids make hole cleaning much more challenging, especially in nearly horizontal well sections. There is a critical angle of inclination between 64 and 69° at which the cleanout efficiencies of all fluids are approximately equal, irrespective of the flow rate. The outcomes of this investigation can be applied in the field to optimize cleanout operations in horizontal and highly deviated wells.
Determinants of Perinatal Mortality in Tercha General Hospital, Southern Ethiopia; Facility Based Case Control Study.
Authors: Tebeje Firehiwot , Addis Animut , Basher Muktar , Hialu Chernet 
Published: September 2019

Abstract
Background: Ethiopia meets the target millennium development goal 4 on child survival three years ahead of time. However, there were high perinatal deaths in the country and the reduction was not impressive. Identifying determinants and implement evidence based interventions is crucial to reduce perinatal death. However, there were no clear evidences on determinants of perinatal mortality in Tercha General Hospital.Objective: To assess determinants of perinatal mortality in Tercha general hospital, Southern Ethiopia, January 1, 2014 and December 30, 2017.Method: An unmatched case control study using secondary data as a source of information was conducted in Tercha general hospital. Cases were stillbirths and early neonatal deaths. Controls were those newborns live till 7th days. Randomly selected 366 (183 cases and 183 controls) study subjects were constituted for this study. The data were collected from March 1-20/2018. Epi-Data version 3.1 and SPSS Version 23 were used for data entry and analysis, respectively. Descriptive statistics were used to describe the study population in relation to study variables. Logistic regressions were employed to identify determinants of perinatal death.Results: In multivariable logistic analysis, rural in residence of the mother [AOR=1.82; 95%CI:(1.04-3.19)], ANC booking [AOR=0.47; 95%CI:(0.27,0.83)], prolonged labour [AOR=2.75; 95%CI: (1.58-4.78)], low birth weight [AOR=1.78; 95%CI (1.06-2.97)], presence of obstetrics complication [AOR=2.15; 95%CI: (1.28-3.62)], using partograph [AOR=0.5; 95%CI: 0.25-0.9]. Using safe child birth checklist [AOR=0.52; 95%CI: 0.30-0.91], and coming with referral [(AOR=2.69; 95% CI: (1.51-4.8)] were significantly associated with perinatal mortality. Conclusion and Recommendation: Being rural in residence, coming with referral, low birth weight, prolonged labour and presence of obstetric complication were associated with elevated the risk of perinatal mortality, and antenatal care booking, using partograph and using safe childbirthchecklist were associated with reduced risk of perinatal mortality. We therefore, recommend strengthening maternal health and newborn care servicesby taking into account these factors to reduce perinatal death.
High-throughput transcriptomic analysis reveals new players in popcorn (Zea mays) aluminum resistance
Authors: Pinto Vitor Batista , Ferreira Priscila Gonçalves , Vidigal Pedro Marcus Pereira , Mendes Tiago Antônio de Oliveira , Dal-Bianco Maximiller , Viana José Marcelo Soriano 
Published: September 2019

Abstract
BackgroundAt the date, the investigation of genes involved in Al resistance has focused mainly in gene expression profiles based on microarray and in short periods of exposure to Al. Under a long term of Al exposure, such as 72 h, resistance maintenance mechanisms might be created in which several metabolic processes are working simultaneously. To investigate new players involved in defense response under Al stress, we tracked the expression profile of two Al-contrasting popcorn inbreed lines during 72 h under Al-stress using Illumina high-throughput mRNA sequencing technology.ResultsA total of 1,121 differentially expressed genes (DEGs) were identified in the Al-sensitive line and 2,872 DEGs in the Al-resistant line, of which 384 were shared in both lines. Genes categorized in lipid metabolic process and oxidation-reduction were present in both lines, but lipid metabolic process was up-regulated in the Al-resistant line but down-regulated in the Al-sensitive line. The biological process category revealed that the down-regulated genes on the Al-resistant line were involved in signaling. The most significant GO modules were clustered in response to a stimulus. Differentially expressed transporters were also found in both lines, including ABC transporters, Nramp, aquaporins, SWEET transporters, Al-activated malate transporter (ALMT), and multidrug and toxic compound extrusion (MATE). Several transcription factors and genes involved in cell wall modifications were also detected.ConclusionsThe Al-resistant line presented genes that play a role in an efficient oxidative system against ROS, involved in cell wall stiffening and dynamic changes of the cell wall to prevent the Al ion transport via the symplast. Also, we detected transporters belonging to families already known to perform a role in Al-detoxification and organic acid exclusion, and we proposed a class of SWEET transporters that might be involved in regulation of vacuolar sugar storage under Al-stress. Although the exact functions of these genes remain to be investigated, these results provide a platform for functional analysis of the defense response against Al-stress in maize.
Academic Achievement and Associated Factors Among Students In Mizan Aman College Of Health Science, Southwest Ethiopia
Authors: Toru Tigistu , Beyene Bereket , Adraro Wasihun , Sahilu Degemu , Anmut Walellign 
Published: September 2019

Abstract
Background College students’ academic performance plays an important role in producing the best quality graduates who was become great leaders and manpower for the country contributing to the nation’s economic and social development . From our best knowledge there is information gap that shows students academic achievement and associated factors in study area.Objective To assess college students academic achievement and associated factors among level 3 and 4 students at Mizan Aman College of health science Bench Maji Zone, South west Ethiopia.Methods Institution based cross sectional study design was employed. 265 students were randomly selected from different departments of college. Interviewer administrated Structured questionnaires adopted from tools used by other studies was used to collect data. Ethical clearance was obtained from Ethical review committee of Mizan Aman College of health science research and publication office. Objective of the study explained to participants and informed consent was obtained before conducting interview.Result: - From a total of 265 sample size, 250 were completed interview and giving 94% response rate. Student’s academic performance which is measured based on whether the students have passed or not the center of competency examination in Mizan Aman collage of health science. Those who passed was found to be 53.3%. In multivariate logistic regression analysis three variables were statistically significant with low student’s academic performance. Those who had habit of reading in library (AOR=3.13, 95% CI: 2.02, 9.27), Attending class regularly (AOR=2.20, 95% CI: 1.28-3.80) and having no history of substance use (AOR=4.14 95% CI 1.65, 22.79) were found to be significantly associated with students academic performance. Conclusion and recommendation According to this study, student’s academic achievement was low which needs further attention to work on reading habits of students, behavioral changes such as restraining from substance use. Regular class attendance is significant factor to influence students’ academic achievement positively or negatively. Therefore, college deans department co-coordinators as well as instructors should focus on students class attendance regularly.
The impact of coexisting diabetes mellitus on clinical outcomes in patients with idiopathic membranous nephropathy: a retrospective observational study
Authors: Xie Zhiyong , Li Zhilian , Dong Wei , Chen Yuanhan , Li Ruizhao , Wu Yanhua , Liang Huaban , Ye Zhiming , Liu Shuangxin , Shi Wei , Liang Xinling 
Published: September 2019

Abstract
Background Idiopathic membranous nephropathy (IMN) is frequently coexisted with diabetes mellitus (DM). We performed this study to investigate the impact of coexisting DM on clinical outcomes in patients with IMN. Methods 206 adult hospitalized patients diagnosed with biopsy-proven IMN were retrospectively studied, including 42 patients coexisted with DM. Clinical outcomes including remission rates, renal outcome and complications were compared between groups. Impact of cyclophosphamide and ciclosporin on metabolism and complications were analyzed in IMN patients coexisting DM. Results IMN patients coexisted with DM were presented with advanced age, lower level of eGFR and hemoglobin. Patients coexisted with DM experienced worse renal function deterioration and higher incidence of infection. COX regression analysis showed that DM was an independent risk factor for renal function deterioration in IMN patients. There was no significant difference in remission rates and incidence of venous thromboembolism between two groups. Further exploration on the impact of therapeutic regimens on complications and metabolism showed that cyclophosphamide and ciclosporin had no significant difference in incidence of complications including infection and venous thromboembolism, and posed comparable influences on blood glucose, uric acid and blood lipids in IMN patients coexisted with DM. Conclusion Coexisting with DM was an independent risk factor for renal function deterioration in IMN patients but didn't influence the remission of proteinuria. There was no difference in the impact of cyclophosphamide and ciclosporin on complications and metabolism including blood glucose, uric acid and blood lipids in IMN patients coexisted with DM.
Prevalence of Modern Contraceptive Use and Associated Factors among Married Women at Quante Town, Gurage Zone Ethiopia, 2019
Authors: Asfaw Sahle Jabo , Asfaw Kelemua Bereda 
Published: September 2019

Abstract
Background: - Using contraceptive method has a number of positive impacts for the health of the public. It reduces unplanned pregnancies as well as minimizes diseases and death of children and mothers . Despite its benefit, very little research has been done concerning the extent of contraceptive use and its contributing factors in women at Quante Town. Therefore, this study is aimed to assess prevalence of modern contraceptives use and associated factors among married women at Quante Town, Gurage Zone Ethiopia. Methods: A community based cross sectional study design was conducted among 388 married women of reproductive age from January to February 2019. A random sampling technique was used to select the study participants. Data was collected using pretested and structured questionnaire by trained data collectors. The data was entered using Epi info version 7. Data analysis was done by using STATA version 14. Strength of association was measured using odds ratio and 95% CI. Statistical significance was declared at p value <0.05. Table was used to present results. Result : The magnitude of current utilization of modern contraceptive was 65.93% among married reproductive age women at the town. Women’s education level (AOR 3.67 95% CI (1.29 – 46.65)), monthly income (AOR 3.71(95 CI 1.74-7.92)), knowledge (AOR 11.01(95 CI 2.80-43.41)) and attitude towards contraceptive method (AOR 5.63(95 CI 2.40-13.21)) showed independent significant association with current use of modern contraceptives. Conclusion: In this study, more than half of married women were currently using modern contraception methods. Women’s education status, income, knowledge and attitude towards contraception were identified as significant determinants of current utilization of contraceptive methods. Increasing women’s knowledge as well as their attitude towards contraception are important strategies to improve contraceptive methods use.
Liver Cirrhosis, Etiology and Clinical Characteristics Disparities among Minority Population
Authors: Tailakh Muhammad Abu , Poupko Liat , Kayyal Najwan , Ali Alsana , Etzion Ohad , Abu-Kaf Heba , Fich Alexander , Yardni David , Nevo-Shor Anat , Ganim Abed Abu , Abu-Freha Naim 
Published: September 2019

Abstract
Background Liver cirrhosis (LC) is a common disease with varied primary causes and ethnic disparities. We aimed to determine the frequency, clinical characteristics, and outcomes of liver cirrhosis among the Arabs population in southern Israel.Methods This retrospective and follow-up study enrolled all patients diagnosed with liver cirrhosis at the gastroenterology and hepatology department or the internal medicine ward. Patient records were reviewed for demographic, clinical data, and mortality. Clinical primary outcomes were defined as death, hepatocellular carcinoma or liver transplantation.Results We included 820 patients 69 (8.4%) Arabs and 752 (91.6%) Jewish patients. Incidence of cirrhosis was much lower among Arabs patients, 5-10/100,000/year, compared with 20-40/100,000 per year in Jewish patients. Age at diagnosis was 42.6±16.9 years among Bedouins compared to 61±13 years (p<0.001) among Jews. The study included 25 (36.2%) male Bedouins and 472 (63%) male Jews (p<0.001). The most frequent causes of liver cirrhosis among Arabs were cryptogenic (24.6%), hepatitis B (18.8%) and autoimmune hepatitis (17.4%), while hepatitis C (41.7%), fatty liver (16.5%) and alcoholic liver disease (15.5%) were most common among Jewish patients. An all-cause mortality of 41.8% was found in Arabs patients, compared to 63.4% in Jewish patients (p<0.001). Primary clinical outcomes were found by 34 (49%) Arabs patients and by 510 (67.9%) Jewish patients (p=0.002), with 46 and 608 events, retrospectively.Conclusions The incidence of liver cirrhosis among Arabs is lower than that in the Jewish population, with disparities in etiology, age at diagnosis, presence of complications and mortality.
Is geographical isolation associated with poorer outcomes for Northern Manitoba First Nation communities?
Authors: Lavoie Josée Gabrielle , Philips-Beck Wanda , Kinew Kathi Avery , Sinclair Stephanie , Kyoon-Achan Grace , Katz Alan 
Published: September 2019

Abstract
Background: For First Nations, geographical isolation is often simultaneously presented as protective (less direct exposure racism, colonial encroachment on land, dispossession, and colonial imposition) and as a risk factor (lack of opportunities to participate in the formal economy, poorer access to services including healthcare). Our study sought to test the assumption that geographical isolation is associated with poorer population health outcomes among First Nations in Manitoba. Methods: We conducted a population-based retrospective time-trend analysis using administrative data housed at the Manitoba Centre for Health Policy. The study included all Manitoba residents eligible under the Manitoba Health Services Plan (1984-2014). We measured premature mortality rates (PMR), and trends in hospitalization rates and length of stay (LOS) for Ambulatory Care Sensitive Conditions (ACSC) in northern and southern First Nations (FN) communities in Manitoba.Results: The PMR was significantly higher in northern FN compared to southern FN. Hospitalization rates for mental health-related conditions were significantly higher in the northern First Nation communities compared to all Manitoba, and rising (southern, change=1.52%, P=0.015; northern, change=5.49%, P<0.0001), and significantly higher in northern compared to southern FN communities. The LOS for all ACSC increased significantly for all Manitoba (change=0.63%, P=0.0011) but not for FN communities. The LOS for mental health-related conditions increased only for the southern FN communities (% change=1.67, P=0.0032). Conclusions: Our results show higher PMR in northern communities, declining slower than for any other Manitoba communities. Our results also show lower hospitalization rate for ACSC in the north, suggesting barriers to prevention and early diagnosis. There remains a large gap in ACSC hospitalization rates between FN and all Manitobans. Further research is warranted to understand the relationship between the changes in the rates of ACSC and the difference in the rates between northern and southern communities.
Identifying a region-level ‘Knowledge Translation Signature’ in rectal cancer surgery – an observational pilot study
Authors: Simunovic Marko , Fahim Christine , Coates Angela , Urbach David , Earle Craig , Grubac Vanja , Brouwers Melissa , O'Brien Mary Ann , Baxter Nancy 
Published: September 2019

Abstract
Background Knowledge translation (KT) interventions can facilitate the implementation of evidence-based practice and help close quality gaps. Across Ontario, since approximately the year 2006, numerous KT interventions have been implemented by the provincial cancer agency or by individual researchers. Ontario is divided administratively into 14 Local Health Integrated Networks (LHINs). We piloted a methodology to summarize and score at the LHIN level all KT activities implemented to improve the quality of rectal surgery (i.e., a KT Signature score).Methods We interviewed stakeholders to identify KT interventions used in respective LHINs over years 2006 to 2014. Results were summarized into narrative and visual forms. KT experts reviewed and scored final summaries using a 20-item KT Signature Assessment Tool. Scores for each item ranged from 1 – 5. Thus scores could range from 20-100 for each LHIN.Results There were thirty interviews. KT experts produced KT Signature scores for each LHIN that were bimodally distributed with an average score for 2 LHINs of 78 (range 73-83) and for 12 LHINs of 30.5 (range 22-38).Conclusion Related to region level KT interventions to improve rectal cancer surgery quality, we identified two KT Signature types. Scores in 12 Ontario LHINs were low reflecting minimal efforts. Two LHINs had high scores reflecting implementation of numerous KT interventions in addition to those encouraged by the provincial cancer agency. Our methods and results require further validation. But they should be of interest to stakeholders implementing interventions designed to improve medical care at a population level.