bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Let’s have that conversation on next quarter’s call”
Authors: Crawford Camiciottoli Belinda 
Published: April 2019

Abstract
In this chapter, I analyse markers of engagement/disengagement used by company executives and financial analysts in two corpora of earnings conference calls that took place before the 2008 global financial crisis (Pre-crisis corpus), and in late 2009 when the crisis was still ongoing (Crisis corpus). Deontic modals with accompanying pronouns were the most frequent form of engagement, while disengagement was encoded mainly by verbal processes marked with negation. Both engagement and disengagement markers were more prominent in the Crisis corpus, suggesting a strategic usage by the participants to achieve distinct professional objectives vis-à-vis a challenging economic environment. The study builds on previous research that highlights the complex interactional dynamics of the earnings call as a high-stakes communicative event (cf. Crawford Camiciottoli 2013).
Multiplying engagement
Authors: Fryer Daniel Lees 
Published: April 2019

Abstract
This paper explores how the textual voice in an online medical research article engages and positions itself with respect to other voices in the communicative context. Taking a systemic-functional, social-semiotic approach, I examine engagement intersemiotically, with regard to the deployment and integration of visual and verbal resources; interstratally, from the levels of (lexico-)grammar (‘from below’) and genre and ideology (‘from above’); and logogenetically, as the text unfolds. The analysis suggests a text that variously opens and closes dialogic space as the textual voice seeks to (dis)align the reader with various positions construed in the text. Some of those positionings cannot be fully appreciated without an intersemiotic perspective, making it an essential part of understanding how experts engage through specialized genres.
Researchers’ move from page to screen
Authors: Engberg Jan , Maier Carmen Daniela 
Published: April 2019

Abstract
The present study belongs to an extensive project that explores how academic knowledge is mediated through new generic structures and publishing formats and provides data comprising research video articles from JoVE, the international Journal of Visualized Experiments.

In order to deal with the implications of video formats in web contexts upon academic user engagement and knowledge building processes, we adopt a multimodal (inter)action approach in our analysis. We show how exploiting the complex hypermodal configurations contribute to changes in the balance of various types of knowledge and to the potential building of new ones. We also show that by embedding the video in a hypermodal context urges academic users to increase their engagement with the article in unprecedented ways.
Recruitment websites and the socialization of new employees
Authors: Breeze Ruth 
Published: April 2019

Abstract
The complex culture of the large corporation today is mainly shaped by persuasive rather than coercive means. In its messages, the company moulds its own identity and proposes roles for the different players through discourse, providing the information that is considered appropriate to each addressee, and suggesting what behaviours are desirable or acceptable. This trend is most intense at the beginning of a person’s life with the firm. How a corporate body engages with would-be and recent recruits is of considerable interest to analysts who focus on the workings of discourse in society. This chapter explores the system of engagement operating multimodally in the recruitment and careers websites of twenty high-profile companies.
Gestural silence
Authors: Fogarty-Bourget Chloë G. , Artemeva Natasha , Fox Janna 
Published: April 2019

Abstract
This chapter reports on a study of multimodal engagement strategies used by instructors while performing chalk talk, the genre of university mathematics lecture. Relying on multimodal data, the study examines how university mathematics instructors engage students in chalk talk through gestures, writing on the chalkboard, and speech. One of the engagement strategies identified in the study is the use of gestural silence, or the absence of the instructor’s hand movement, intended to engage students in doing mathematics. The study indicates that such multimodal engagement strategies appear to be shaped by the embodied nature of discipline-specific genres.
Ein treuer Freund und guter Verbündeter
Authors: Fuchs Irmgard 
Published: April 2019

Zusammenfassung
Am Anfang der europäischen Tierepik steht der Roman de Renart, eine Sammlung altfranzösischer Erzählungen. Ausgehend von ihm verbreitet sich der Erzählstoff in einer deutschen und einer niederländischen Erzähltradition über Europa. Auch wenn die Fassungen auf derselben stofflichen Vorlage basieren, zeigen bereits die je unterschiedlichen Erzählstrukturen, dass die Dichter beim Wiedererzählen jeweils eigene Akzente gesetzt haben. Dies hat auch Folgen für den Umgang mit Themen wie 'Treue', einem Schlüsselbegriff der höfischen Kultur. Der vorliegende Beitrag untersucht Le Roman de Renart, Van den vos Reynaerde und Reinhart Fuchs anhand einer ihnen gemeinsamen Szene, nämlich der ersten Vorladung des Fuchses durch den Bären. Nach Erläuterungen zum Bedeutungsspektrum von 'Treue' werden die drei Fassungen miteinander verglichen. Dabei ist zu fragen, wie der niederländische Dichter und der deutsche Dichter den gegebenen Erzählstoff umgestaltet haben und wie in ihren Erzählungen 'Treue' auf narrativer und semantischer Ebene präsentiert wird.
A selective survey of visual representations of Reynardian Literature and fox lore in the last fifty years
Authors: Varty Kenneth , Wackers Paul 
Published: April 2019

Abstract
This article offers a survey of fifty years research into Reynardian iconography. It analyses secondary and primary sources: it discusses a number of book length studies, it shows trends in articles, makes suggestions for further research, describes the properties of and the main research on the major illustration cycles of Reynardian literature and ends with an annotated bibliography.
Report on the comparison of the calibration of noble metal thermocouples from 419 ºC up to 1100 ºC (EURAMET.T-S5)
Authors: Campo Dolores del , García Izquierdo Carmen , Petrusova Olgica , Soto Juan Carlos 
Published: April 2019

An International Comparison on the calibration of noble metal thermocouples from 419 °C up to 1100 °C has been carried out among the National Metrology Institutes (NMIs) of Spain, FYR Macedonia and Chile. Measurements were performed from March 2016 to June 2017. One type R thermocouple circulated between the participants that was calibrated by using fixed points or by comparison, depending of the capabilities of the laboratories. The Centro Español de Metrología (Spanish NMI), CEM, acted as the pilot laboratory providing the reference value of the comparison.
The thermocouple shown an acceptable behavior throughout the comparison, with no critical deterioration of its homogeneity and a maximum drift lower than 2 μV in the worst case. The results of the comparison were quite satisfactory. The three institutes are compatible with a coverage factor k= 2 in all the calibration points and in the case of aluminum and zinc they are even compatible for a coverage factor k = 1.
This report presents the results of this comparison and provides detailed information of the measurements performed by the participating laboratories.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCT, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Thermodynamic Stability, Half-Metallic and Optical Properties of Sc2CoSi [001] Film: a DFT Study
Authors: Amiri Maliheh , Akbari Hossein , Nedaee-shakarab Bashir , Boochani Arash , Aminian Amin , Zangeneh Yousof , Naderi Sirvan 
Published: April 2019

Abstract

The electronic and optical characteristics of the Sc
2
CoSi Heusler with L21 structure and also the surface effect on electronic and optical properties, and the films thermodynamic stability of the [001] direction in four cases including: Sc-Sc, Sc-Co, Sc-Si and Co-Si terminations are studied using the first principles calculations (FPLAPW) within the framework of the density functional theory (DFT). The band structure calculations represent the ferromagnetic half-metallic properties with 100% spin polarization and 0.54 eV indirect gap in spin down for Sc
2
CoSi bulk with optimized lattice parameters of 6.25 Å. The total magnetic moment obtained for this compound is −1.0 μB, which is in accordance with Slater-Pauling rule. The half-metallic (HM) behavior by 100% spin polarization at Fermi level is occurred in the Sc-Si termination with a 0.32 eV gap in down spin. The optical responses have been calculated for the bulk and Sc-Si termination by a red shift in these parameters and the metallic treatments have been increased. According to the thermodynamic phase diagrams, it is shown the Sc-Si and Sc-Sc terminations are more stable than other terminations.
Cross-sectional Association Between Blood Pressure Status and Atrial Fibrillation in an Elderly Chinese Population
Authors: Chen Yi , Huang Qi-Fang , Sheng Chang-Sheng , Lei Lei , Xu Shao-Kun , Zhang Wei , Shao Shuai , Wang Dian , Cheng Yi-Bang , Wang Ying , Guo Qian-Hui , Zhang Dong-Yan , Li Yan , Li Yong , Freedman S Ben , Wang Ji-Guang 
Published: April 2019

Abstract

OBJECTIVE
Atrial fibrillation (AF) and hypertension are prevalent chronic disease conditions in the elderly population. In the present cross-sectional study, we investigated the association between blood pressure (BP) and AF in an elderly Chinese population.

METHOD
Our elderly (≥65 years) subjects were residents recruited from 6 communities in Shanghai from 2006 to 2017. Atrial fibrillation was systematically screened by rest 12-lead electrocardiogram (ECG) or by a handheld single-lead ECG. BP status was defined according to the European hypertension guidelines as optimal, normal, or high-normal BP, and stage 1, 2, or 3 hypertension.

RESULT
In the 6,966 participants (women 56.0%, mean age: 72.3 years), the prevalence of AF was 3.3%, and the prevalence of hypertension was 58.7% (83.7% treated). In all participants, the association with prevalent AF was negative for systolic BP (odds ratio [OR] per 10-mm Hg increase 0.79, 95% confidence interval [CI]: 0.71–0.88, P &lt; 0.0001) but positive for diastolic BP (OR per 5-mm Hg increase 1.11, 95% CI: 1.02–1.22, P = 0.02). In untreated participants (n = 3,544), the association with prevalent AF was U-shaped for both systolic and diastolic BP, with the nadir at high-normal BP and a significantly higher risk of prevalent AF in optimal systolic BP (OR: 3.11, 95% CI: 1.65–5.85, P = 0.004) and stage 2 or 3 diastolic hypertension relative to the nadir (OR: 8.04, 95% CI: 2.28–28.3, P = 0.001).

CONCLUSION
In the elderly population, BP shows a complicated relationship with prevalent AF, with high-normal BP at the lowest risk and optimal systolic BP and stage 2 or 3 diastolic hypertension at increased risks.
MethylSeqDesign: a framework for Methyl-Seq genome-wide power calculation and study design issues
Authors: Liu Peng , Lin Chien-Wei , Park Yongseok , Tseng George 
Published: April 2019

SummaryBisulfite DNA methylation sequencing (Methyl-Seq) becomes one of the most important technologies to study methylation level difference at a genome-wide scale. Due to the complexity and large scale of methyl-Seq data, power calculation and study design method have not been developed. Here, we propose a “MethylSeqDesign” framework for power calculation and study design of Methyl-Seq experiments by utilizing information from pilot data. Differential methylation analysis is based on a beta-binomial model. Power calculation is achieved using mixture model fitting of p-values from pilot data and a parametric bootstrap procedure. To circumvent the issue of existing tens of millions of methylation sites, we focus on the inference of pre-specified targeted regions. The performance of the method was evaluated with simulations. Two real examples are analyzed to illustrate our method. An R package “MethylSeqDesign” to implement this method is publicly available.
The clinical spectrum of the congenital myasthenic syndrome resulting from COL13A1 mutations
Authors: Rodríguez Cruz Pedro M. , Cossins Judith , de Paula Estephan Eduardo , Munell Francina , Selby Kathryn , Hirano Michio , Maroofin Reza , Mehrjardi Mohammad Yahya Vahidi , Chow Gabriel , Carr Aisling , Manzur Adnan , Robb Stephanie , Munot Pinki , Wei Liu Wei , Banka Siddharth , Fraser Harry , De Goede Christian , Zanoteli Edmar , Conti Reed Umbertina , Sage Abigail , Gratacos Margarida , Macaya Alfons , Dusl Marina , Senderek Jan , Töpf Ana , Hofer Monika , Knight Ravi , Ramdas Sithara , Jayawant Sandeep , Lochmüller Hans , Palace Jacqueline , Beeson David 
Published: April 2019

AbstractNext generation sequencing techniques were recently used to show mutations in COL13A1 cause synaptic basal lamina-associated congenital myasthenic syndrome type 19. Animal studies showed COL13A1, a synaptic extracellular-matrix protein, is involved in the formation and maintenance of the neuromuscular synapse that appears independent of the Agrin-LRP4-MuSK-DOK7 acetylcholine receptor clustering pathway. Here, we report the phenotypic spectrum of 16 patients from 11 kinships harbouring homozygous or heteroallelic mutations in COL13A1. Clinical presentation was mostly at birth with hypotonia and breathing and feeding difficulties often requiring ventilation and artificial feeding. Respiratory crisis related to recurrent apnoeas, sometimes triggered by chest infections, were common early in life but resolved over time. The predominant pattern of muscle weakness included bilateral ptosis (non-fatigable in adulthood), myopathic facies and marked axial weakness, especially of neck flexion, while limb muscles were less involved. Other features included facial dysmorphism, skeletal abnormalities and mild learning difficulties. All patients tested had results consistent with abnormal neuromuscular transmission. Muscle biopsies were within normal limits or showed non-specific changes. Muscle MRI and serum creatine kinase levels were normal. In keeping with COL13A1 mutations affecting both synaptic structure and presynaptic function, treatment with 3,4-diaminopyridine and salbutamol resulted in motor and respiratory function improvement. In non-treated cases, disease severity and muscle strength improved gradually over time and several adults recovered normal muscle strength in the limbs. In summary, patients with COL13A1 mutations present mostly with severe early-onset myasthenic syndrome with feeding and breathing difficulties. Axial weakness is greater than limb weakness. Disease course improves gradually over time, which could be consistent with the less prominent role of COL13A1 once the neuromuscular junction is mature. This report emphasizes the role of collagens at the human muscle endplate and should facilitate the recognition of this disorder, which can benefit from pharmacological treatment.
Integration of transthoracic focused cardiac ultrasound in the diagnostic algorithm for suspected acute aortic syndromes
Authors: Nazerian Peiman , Mueller Christian , Vanni Simone , Soeiro Alexandre de Matos , Leidel Bernd A , Cerini Gabriele , Lupia Enrico , Palazzo Andrea , Grifoni Stefano , Morello Fulvio 
Published: April 2019

Abstract

Aims
The diagnosis of acute aortic syndromes (AASs) is challenging and requires integrated strategies. Transthoracic focused cardiac ultrasound (FoCUS) is endorsed by guidelines as a first-line/triage tool allowing rapid bedside assessment of the aorta. However, the performance of FoCUS in the European Society of Cardiology-recommended workup of AASs awaits validation.

Methods and results
This was a prespecified subanalysis of the ADvISED multicentre prospective study. Patients with suspected AAS underwent FoCUS for detection of direct/indirect signs of AAS. Clinical probability assessment was performed with the aortic dissection detection risk score (ADD-RS). Case adjudication was based on advanced imaging, surgery, autopsy, or 14-day follow-up. An AAS was diagnosed in 146 (17.4%) of 839 patients. Presence of direct FoCUS signs had a sensitivity and specificity of 45.2% [95% confidence interval (CI) 37–53.6%] and 97.4% (95% CI 95.9–98.4%), while presence of any FoCUS sign had a sensitivity and specificity of 89% (95% CI 82.8–93.6%) and 74.5% (95% CI 71–77.7%) for AAS. The additive value of FoCUS was most evident within low clinical probability (ADD-RS ≤1). Herein, direct FoCUS signs were identified in 40 (4.8%) patients (P &lt; 0.001), including 29 with AAS. ADD-RS ≤1 plus negative FoCUS for AAS rule-out had a sensitivity of 93.8% (95% CI 88.6–97.1%) and a failure rate of 1.9% (95% CI 0.9–3.6%). Addition of negative D-dimer led to a failure rate of 0% (95% CI 0–1.2%).

Conclusion
FoCUS has additive value in the workup of AASs. Direct FoCUS signs can rapidly identify patients requiring advanced imaging despite low clinical probability. In integrated bundles, negative FoCUS is useful for rule-out of AASs.
Non-paroxysmal atrial fibrillation mapping: characterization of the electrophysiological substrate using a novel integrated mapping technique
Authors: Ciconte Giuseppe , Vicedomini Gabriele , Li Wenwen , Mangual Jan O , McSpadden Luke , Ryu Kyungmoo , Saviano Massimo , Vitale Raffaele , Conti Manuel , Ćalović Žarko , Santinelli Vincenzo , Pappone Carlo 
Published: April 2019

AbstractAimsClinical outcomes after radiofrequency catheter ablation (RFCA) remain suboptimal in the treatment of non-paroxysmal atrial fibrillation (AF). Electrophysiological mapping may improve understanding of the underlying mechanisms. To describe the arrhythmia substrate in patients with persistent (Pers) and long-standing persistent (LSPers) AF, undergoing RFCA, using an integrated mechanism mapping technique.Methods and resultsPatients underwent high-density electroanatomical mapping before and after catheter ablation. Integrated maps characterized electrogram (EGM) cycle length (CL) in regions with repetitive–regular (RR) activations, stable wavefront propagation, fragmentation, and peak-to-peak bipolar voltage. Among 83 patients (72% male, 60 ± 11 years old), RR activations were identified in 376 regions (mean CL 180 ± 31 ms). PersAF patients (n = 43) showed more RR sites per patient (5.3 ± 2.4 vs. 3.7 ± 2.1, P = 0.002) with faster CL (166 ± 29 vs. 190 ± 29 ms; P < 0.001) and smaller surface area of fragmented EGMs (15 ± 14% vs. 27 ± 17%, P < 0.001) compared with LSPersAF. The post-ablation map in 50 patients remaining in AF, documented reduction of the RR activities per patient (1.5 ± 0.7 vs. 3.7 ± 1.4, P < 0.001) and area of fragmentation (22 ± 17% vs. 8 ± 9%, P < 0.001). Atrial fibrillation termination during ablation occurred at RR sites (0.48 ± 0.24 mV; 170.5 ± 20.2 ms CL) in 31/33 patients (94%). At the latest follow-up, arrhythmia freedom was higher among patients receiving ablation >75% of RR sites (Q4 82.6%, Q3 63.1%, Q2 35.1%, and Q1 0%; P < 0.001).ConclusionThe integrated mapping technique allowed characterization of multiple arrhythmic substrates in non-paroxysmal AF patients. This technique might serve as tool for a substrate-targeted ablation approach.
Organization and regulation of cyanobacterial nif gene clusters: implications for nitrogenase expression in plant cells
Authors: Thiel Teresa 
Published: April 2019

ABSTRACT
For over 50 years scientists have considered the possibility of engineering a plant with nitrogen fixation capability, freeing farmers from their dependence on nitrogen fertilizers. With the development of the tools of synthetic biology, more progress has been made toward this goal in the last 5 years than in the previous five decades. Most of the effort has focused on nitrogenase genes from Klebsiella oxytoca, which has complex gene regulation. There may be advantages in using nitrogenase genes from cyanobacteria, which comprise large polycistronic gene clusters that may be easier to manipulate and eventually express in a plant. The fact that some diatoms have a cyanobacterial nitrogen fixing organelle further supports the idea that a cyanobacterial nitrogenase gene cluster may function in a newly-engineered, cyanobacterial-based plant organelle, a nitroplast. This review describes recent attempts to express the nif genes from Anabaena variabilis ATCC 29413, Leptolyngbya boryana dg5 and Cyanothece sp. ATCC 51142 in heterologous cyanobacteria in the context of the organization of the nitrogenase genes and their regulation by the transcription factor CnfR via its highly conserved binding sites.
Buckling behaviour of trees under self-weight loading
Authors: Dargahi Mojtaba , Newson Timothy , Moore John 
Published: April 2019

AbstractUnderstanding tree stability under self-weight and applied loads from wind and snow is important when developing management strategies to reduce the risk of damage from these abiotic agents. In this paper, linear buckling analysis was conducted using the finite element method to identify the instability modes of a tree structure under a specified set of loads. A non-prismatic elastic circular column of height H was analysed, taking self-weight into account. Various scenarios were considered: column taper, base rigidity, radial and longitudinal stiffness, ellipticity and crown weight. The effect on the critical buckling height was assessed in each case. Validation against closed form solutions of benchmark problems was conducted satisfactorily. The results indicate that column taper, base rigidity and the stiffness/density ratio are particularly important for this problem. Further comparison was made using data from a 15-year old Pinus radiata stand in New Zealand, which contained both buckled and non-buckled trees. While the model predicted factors of safety against buckling that were close to unity, it was unable to differentiate between buckled and non-buckled trees. Further investigation is needed to examine the reasons why this occurred. Despite this, the current study provides an in-depth numerical investigation, which has aided our understanding of the effects that material properties, geometric properties and boundary conditions have on buckling phenomenon in trees.
Accounting for uncertain fault geometry in earthquake source inversions – II: application to the Mw 6.2 Amatrice earthquake, central Italy
Authors: Ragon Théa , Sladen Anthony , Simons Mark 
Published: April 2019

SUMMARY
Our understanding of earthquake sources is limited by the availability and the quality of observations and the fidelity of our physical models. Uncertainties in our physical models will naturally bias our inferences of subsurface fault slip. These uncertainties will always persist to some level as we will never have a perfect knowledge of the Earth’s interior. The choice of the forward physics is thus ambiguous, with the frequent need to fix the value of several parameters such as crustal properties or fault geometry. Here, we explore the impact of uncertainties related to the choice of both fault geometry and elastic structure, as applied to the 2016 Mw 6.2 Amatrice earthquake, central Italy. This event, well instrumented and characterized by a relatively simple fault morphology, allows us to explore the role of uncertainty in basic fault parameters, such as fault dip and position. We show that introducing uncertainties in fault geometry in a static inversion reduces the sensitivity of inferred models to different geometric assumptions. Accounting for uncertainties thus helps infer more realistic and robust slip models. We also show that uncertainties in fault geometry and Earth’s elastic structure significantly impact estimated source models, particularly if near-fault observations are available.