bluuebunny/crossref_metadata_2025_split huggingface dataset:
A scalable and multibias parameter extraction method for a small‐signal GaN HEMT model
Authors: Chen Yongbo , Xu Yuehang , Wang Feng , Wang Changsi , Wu Qingzhi , Qiao Shiyang , Yan Bo , Xu Ruimin 
Published: April 2018

AbstractIn this paper, a scalable and multibias parameter extraction method for gallium nitride high electron mobility transistor small‐signal model has been proposed. The main advantage of this method is that the temperature‐dependent access resistances and nonlinear thermal resistance have been taken into account, which makes the extracted access resistances and intrinsic elements more physical and reliable at different bias conditions for various device dimensions. The new modeling method has been validated by comparing the simulated small‐signal S‐parameters with the measured data over a wide range of frequency.
Conditional deletion of Neurog1 in the cerebellum of postnatal mice delays inhibitory interneuron maturation
Authors: Obana Edwin A. , Zhou Qiong , Furmanski Orion , Doughty Martin L. 
Published: April 2018

AbstractThe transcriptional programs that drive the generation of diverse GABAergic neuron populations from their common progenitor pools in the developing cerebellum remain unclear. Neurog1 is a pro‐neural basic helix‐loop‐helix transcription factor expressed in GABAergic progenitor cells in the ventricular zone (VZ) of embryos and subsequently in the presumptive white matter (pWM) tracts of developing postnatal mice. Genetic inducible fate‐mapping labels Purkinje cells and all inhibitory interneuron cell types of the cerebellar cortex. As conventional Neurog1Neo knockout (KO) mice are neonatal lethal, we generated Neurog1loxP mutant mice to examine the effects of conditional Neurog1 deletion on the postnatal development of the cerebellum. Targeted Neurog1 loss‐of‐function in the developing cerebellum does not result in significant differences in cerebellar morphology or in the number of GABAergic neurons in the cerebellar cortex of mice at postnatal day 21 (P21). To determine the effects of Neurog1 deletion on GABAergic progenitors, we quantified rates of cell proliferation and cell cycle progression or re‐entry in embryonic Neurog1Neo and postnatal Neurog1loxP mutants. The data revealed no significant effect of Neurog1 loss‐of‐function on embryonic day 12.5 (E12.5) VZ progenitors or on P5 and P6 progenitors in the pWM at P7. However, 4–5 day pulse‐labeling of P5 and P6 progenitors revealed reductions in inhibitory interneuron dispersal from the pWM to the cerebellar cortex in P10 conditional Neurog1loxP/loxP KO mice. Thus, our conditional Neurog1 KO approach reveals a requirement for Neurog1 activity in inhibitory interneuron cell dispersal from pWM tracts in the developing cerebellum of postnatal mice.
Keeping work and private life apart: Age‐related differences in managing the work–nonwork interface
Authors: Spieler Ines , Scheibe Susanne , Stamov Roßnagel Christian 
Published: April 2018

SummaryInitial evidence suggests that older workers enjoy higher work–life balance than young workers. Yet little is known about the mechanisms of this effect or the robustness of age differences when accounting for differences in life context. We introduce and test the boundary management account of aging and work–life balance, which suggests that older workers maintain stronger work–nonwork boundaries as a pathway toward work–life balance. Both in Study 1 (cross‐sectional; N = 298 bank employees) and in Study 2 (aggregated diary entries; N = 608 workers), older workers reported better work–life balance and stronger boundaries at work than young workers; and stronger boundaries at home (Study 1). In both studies, stronger boundaries were related to better work–life balance, and boundary strength mediated the relationship between age and work–life balance. Study 2 additionally suggests that the use of boundary management strategies is responsible for stronger boundaries at higher age. Analyses accounted for differences in family and work context characteristics (both studies) and boundary preferences (Study 1). The findings corroborate evidence of older workers' enhanced work–life balance and suggest that it results from more successful boundary management with age rather than merely from changes in contextual factors or boundary preferences.
A dynamic phase model of psychological contract processes
Authors: Rousseau Denise M. , Hansen Samantha D. , Tomprou Maria 
Published: April 2018

SummaryIn formulating a dynamic model of psychological contract (PC) phases, this paper offers new insights by incorporating a temporal perspective into the study of the PC. Although conceptualized as a dynamic construct, little empirical attention has been directed at how PCs evolve and change over time. Moreover, conceptualization of the PC and its processes has undergone limited revision since the 1990s despite challenges to some of its tenets and advances in related fields that suggest the importance of time to such processes. In this article, we address limitations in existing theory, clarify the conceptualization of the PC, and bring dynamism to the forefront of PC theory building by emphasizing dynamic processes. We propose a phase‐based model of PC processes (intraphase and interphase) wherein the functions of key variables (e.g., promises, inducements, contributions, and obligations) change over time and context. These phases include creation, maintenance, renegotiation, and repair. This model directs attention to the dynamic nature of the PC, drawing on contemporary evidence regarding self‐regulatory mechanisms. Finally, we present the implications of this dynamic phase model for theory and research.
Explaining dyadic expertise use in knowledge work teams: An opportunity–ability–motivation perspective
Authors: Hong Woonki , Gajendran Ravi Shanker 
Published: April 2018

SummaryOrganizations use project teams to lower search costs associated with locating expertise by assembling requisite expertise within a single unit. But prior research suggests that availability of expertise in teams does not guarantee its use. When are team members more likely to reach out to their peers for their expertise? To answer this question, this paper develops a theoretical model predicting dyadic expertise use in teams based on the opportunity–ability–motivation framework of behavior in organizations. We argue that 3 complementary conditions influence dyadic expertise use in teams: A focal team member is more likely to use a peer's expertise in a specific domain when the peer is perceived to have valuable expertise (opportunity), when the member is psychologically empowered (motivation), and when the member shares a strong tie with the peer (ability). We tested our framework using a 2‐wave dataset consisting of 1,898 observations of dyadic domain‐specific peer expertise use based on 71 members rating 166 peers nested within 22 teams. Findings suggest that tie strength and psychological empowerment jointly moderate the relationship between perceived peer expertise level and peer expertise use.
Ambient‐light‐adaptive image quality enhancement for full‐color e‐paper displays using a saturation‐based tone‐mapping method
Authors: Qin Zong , Chen Yi‐Wen , Lin Fang‐Cheng , Hung Chi‐Mao , Shieh Han‐Ping David , Huang Yi‐Pai 
Published: April 2018

AbstractFull‐color e‐paper displays that have a small color gamut encounter image tone distortions and contour artifacts in high‐saturation regions. To solve these issues, in this paper, we comprehensively measure the colorimetric responses of input image signals and demonstrate that the perceptual colorfulness in terms of chroma abnormally declines when the input saturation is beyond a certain value. Accordingly, saturation‐based tone‐mapping curves are developed to map the abnormal high saturation to the range that the display is able to normally render. By testing several test charts and natural images, the recoveries of the original image tones and the removals of the contour artifacts are experimentally verified. More important, by discussing how to conduct a database of tone‐mapping curves for different ambient lights and utilize the database for an unknown ambient light, the proposed method is proven to be completely ambient light adaptive.
Transparent AMOLED display driven by split oxide TFT backplane
Authors: Lee Suhui , Chen Yuanfeng , Kim Jeonggi , Kim Hyo‐Min , Jang Jin 
Published: April 2018

AbstractWe have developed stable and high performance etch‐stopper amorphous indium–gallium–zinc oxide thin‐film transistor (TFT) by using split active oxide semiconductor. The amorphous indium–gallium–zinc oxide TFTs exhibit the mobility as high as over 70 cm2/Vs and the stable operation under positive bias temperature stress. In this work, we demonstrated a 4‐in. transparent active‐matrix organic light‐emitting diode display using oxide TFT backplane with split active layer, where the gate driver is integrated.
Multidimensional analyses of the learning curve for single‐incision plus one port laparoscopic surgery for sigmoid colon and upper rectal cancer
Authors: Li Junmeng , Wang Yanan , Liu Dong , Zhou Haipeng , Mou Tingyu , Li Guoxin , Deng Haijun 
Published: April 2018

Background and ObjectivesSingle‐incision plus one port surgery (SILS + 1) provides the advantages of being minimally invasive and easier to perform than pure single‐incision laparoscopic surgery. The aim of this study was to investigate the learning curve (LC) for SILS + 1 for sigmoid colon and upper rectal cancer.MethodFrom November 2012 to May 2014, a series of 85 consecutive patients underwent selective SLIS + 1 for sigmoid colon and upper rectal cancer performed by a single surgeon at Nanfang Hospital. The LC for SILS + 1 was evaluated using cumulative sum control chart (CUSUM) and risk‐adjusted CUSUM methods. Data for all the perioperative variables and pathologic results among the phases were compared.ResultsThe LC had three phases: phase 1 (cases 1‐13) was the initial learning period; phase 2 (cases 14‐44) was the learning plateau period; and phase 3 (cases 45‐85) was the competent period. The differences in total operating time among the three phases were significant. The number of harvested lymph nodes increased along with increases in the surgeon's experience.ConclusionsFor experienced CLS surgeons, the learning process reached the plateau period after the 13th case, and technical competence was achieved after the 44th case.
Superb Microvascular Imaging of the Median Nerve in Carpal Tunnel Syndrome: An Electrodiagnostic and Ultrasonographic Study
Authors: Karahan Ali Yavuz , Arslan Serdar , Ordahan Banu , Bakdik Suleyman , Ekiz Timur 
Published: April 2018

ObjectiveTo evaluate intraneural blood flow of the median nerve using superb microvascular imaging (SMI) and power Doppler ultrasonography (PDUS), and to examine their correlation with electroneuromyography in patients with carpal tunnel syndrome (CTS).MethodsA cross‐sectional survey was used, and the study was conducted in the research unit of a training and research hospital. Patients diagnosed with CTS according to electroneuromyography studies were included in the study. Ultrasound measurements were taken using an Aplio‐500 (Toshiba Medical System Corporation, Tokyo, Japan) device and a linear multifrequency 14‐MHz probe. The cross‐sectional area of the median nerve at the carpal tunnel level was measured by the direct tracing method using electronic calipers. The power Doppler ultrasonography and superb microvascular imaging scores were recorded by grading the vascularity between 0 and 3.ResultsEvaluation was made of a total of 113 hands of 80 patients (18 men, 62 women) with a mean age of 34.67 ± 12.82 years. The mean duration of symptoms was 12.34 ± 6.66 months. When the patients were grouped as mild, moderate, and severe CTS, there was a statistically significant difference between the SMI and PDUS grades (P < .05). As the severity of CTS increased, an increase in SMI and PDUS scores was observed. There was a strong correlation between SMI scores and motor distal latency (r = .71/P = .026), amplitude of sensory action potential (r = −.77/P = .029), and sensory neurotransmission rate (r = .77/P = .029).ConclusionSMI seems to be more sensitive than PDUS for evaluating the vascularity of the median nerve in patients with CTS, and SMI grading is correlated with the ENMG results.
The influential factors on the morphological changes of upper airway associated with mouth opening
Authors: Hu Bin , Ye Jingying , Yin Guoping , Zhang Yuhuan 
Published: April 2018

ObjectiveThis study aimed to evaluate the influential factors on the morphological changes of upper airway caused by mouth opening (MO).MethodsOne hundred and thirty‐eight obstructive sleep apnea–hypopnea syndrome (OSAHS) patients were enrolled. Anthropometric and demographic data, Friedman tongue position (FTP), and tonsil scores were recorded. Overnight polysomnography and upper airway computed tomography scans under two conditions (mouth closed [MC] and MO) were acquired. Morphological parameters of upper airway were compared between MC and MO. Stepwise multiple linear regression analyses were performed with the variation ratio of upper airway parameters (Para‐VRs) from MC to MO as the dependent variable, with age, gender, body mass index, neck circumference, waist circumference, four mandibular indexes, net angle or amount of MO, FTP, and tonsil scores as the independent variables.ResultsOverall analysis and subgroup analyses based on OSAHS severity revealed that the minimal cross‐sectional area of oropharyngeal lumen (OXmin) significantly decreased (P < 0.05) with MO, whereas the minimal cross‐sectional area of velopharyngeal lumen (VXmin) did not significantly change with MO (P > 0.05). The net angle of MO or amount of MO combined with tonsil scores were identified to have significant positive correlation with EXP (OXmin‐VR), [OXmin‐VR was logarithmically transformed with an exponential function, EXP(n) = en]; FTP appeared to be more related to EXP (VXmin‐VR). Mouth opening induced a significant increase VXmin for patient subgroup with FTP grading I and a significant decrease VXmin for patient subgroup with FTP grading IV (P < 0.05).ConclusionWider MO combined with larger tonsils lead to narrower oropharyngeal airway. The relative position of tongue to soft palate is the main factor influencing the changes of velopharyngeal lumen with MO.Level of Evidence4 Laryngoscope, 128:2902–2909, 2018
Decreased Serum Levels of Sphingomyelins and Ceramides in Sickle Cell Disease Patients
Authors: Aslan Mutay , Kıraç Ebru , Kaya Sabriye , Özcan Filiz , Salim Ozan , Küpesiz Osman Alphan 
Published: April 2018

AbstractLimited data are available on the serum levels of different sphingomyelin (CerPCho) and ceramide (CER) species in sickle‐cell disease (SCD). This study was aimed at identifying the levels of C16–C24 CerPCho and C16–C24 CER in serum obtained from SCD patients and controls. Circulating levels of neutral sphingomyelinase (N‐SMase) activity, ceramide‐1‐phosphate (C1P), and sphingosine‐1‐phosphate (S1P) were also determined. Blood was collected from 35 hemoglobin (Hb)A volunteers and 45 homozygous HbSS patients. Serum levels of C16–C24 CerPCho and C16–C24 CER were determined by an optimized multiple reaction monitoring (MRM) method using ultrafast liquid chromatography (UFLC) coupled with tandem mass spectrometry (MS/MS). Serum activity of N‐SMase was assayed by standard kit methods, and C1P and S1P levels were determined by enzyme‐linked immunosorbent assay. A significant decrease was observed in the serum levels of C18–C24 CerPCho in patients with SCD compared to controls. No significant difference was found in C16 CerPCho levels between the two groups. Very‐long‐chain C22–C24 CER were significantly decreased in SCD, while long‐chain C16–C20 CER levels showed no significant difference between SCD patients and controls. Significant positive correlation was found between the serum total cholesterol levels and C18–C24 CerPCho and C22–C24 CER in SCD patients. Patients with SCD had significantly elevated serum activity of N‐SMase as well as increased circulating levels of C1P and S1P compared to controls. The decrease in serum levels of C18–C24 CerPCho in patients with SCD was accompanied by decreased levels of C22–C24 CER. Future studies are needed to understand the role of decreased CerPCho and CER in the pathophysiology of SCD.
Noncholesterol Sterols as Surrogate Markers in Patients with Severe Alcoholic Hepatitis
Authors: Sahlman Perttu , Nissinen Markku , Simonen Piia , Färkkilä Martti 
Published: April 2018

AbstractSevere alcoholic hepatitis (AH) is a life‐threatening condition lacking good serologic markers to tailor treatment and predict recovery. We examined the cholesterol metabolism in severe AH to explore prognostic markers and evaluate the profile of cholesterol precursors, cholestanol and phytosterols, in this context. We assessed serum cholesterol, cholesterol precursors, cholestanol, phytosterols, and biochemical markers in 24 patients with severe AH treated with prednisolone and randomized to ciprofloxacin in the ratio 1:1. Response to prednisolone was assessed with the Lille model. Evaluations were made between responders and nonresponders to corticosteroid treatment and during follow‐up for 180 days. The findings were compared with those from patients with primary sclerosing cholangitis (PSC) (n = 156) and healthy individuals (n = 124). Responders to prednisolone had ~56–60% higher (p‐value 0.032–0.044) serum ratios to cholesterol of phytosterols, while the lathosterol/campesterol ratio was ~76% (p = 0.031) lower compared to nonresponders. Stigmasterol/cholesterol predicted response to corticosteroid therapy. Surrogate markers of cholesterol synthesis (lathosterol and desmosterol) inversely reflected those of absorption (cholestanol and phytosterols) in PSC and controls (r‐range −0.247 to −0.559, p < 0.01 for all), contrary to AH patients, among whom this reciprocal regulation was partially recovered on day 90 (lathosterol: r‐range −0.733 to −0.952, p < 0.05 for all). AH patients had ~26% lower lathosterol/cholesterol, but 1.13–3.87‐fold higher cholestanol/cholesterol and sitosterol/cholesterol compared to control groups (p < 0.05 for all). Median ferritin concentration at baseline was ~37% lower (p = 0.011) among the responders. Cholesterol precursors and phytosterols have a disease‐specific profile in AH. Phytosterols and ferritin may serve as surrogate markers for short‐term response.
Treatment of atrophic acne scarring with fractional micro‐plasma radio‐frequency in Chinese patients: A prospective study
Authors: Lan Ting , Xiao Yan , Tang Li , Hamblin Michael R. , Yin Rui 
Published: April 2018

BackgroundAcne scarring is a common disfiguring sequela of acne vulgaris which can lead to serious psychosocial problems and have a negative effect on patients’ quality of life. Although a variety of approaches can be used to treat atrophic acne scars, disadvantages such as long‐healing time, dyspigmentation, infections, and prolonged erythema make these treatments unsatisfactory especially for Asians. Fractional micro‐plasma radio‐frequency is a novel technology that produces minor ablation to the epidermis to promote rapid re‐epithelialization, while the radio‐frequency evoked thermal effect can stimulate regeneration and remodeling of dermal fibroblasts.ObjectiveTo evaluate the clinical effectiveness and safety of micro‐plasma radio‐frequency for the treatment of facial acne scars in Chinese patients.Materials and MethodsA total of 95 patients with facial atrophic acne scars were treated by micro‐plasma radio‐frequency using three sessions at 2‐month intervals. Patients were seen 1 week after each treatment and 1, 3, 6 months after the final treatment. Improvement was assessed by three independent dermatologists who compared photographs taken before the first treatment and 6 months after the last treatment. Adverse effects were evaluated by a dermatologist who did not participated in the study. Patients also provided self‐evaluation of satisfaction levels at the last follow‐up visit.ResultsA total of 86 patients with atrophic acne scars completed the entire study. There was a significant improvement in acne scars after three treatments. The mean score of ECCA grading scale (Echelle d'Evaluation Clinique des Cicatrices d'Acné) was reduced from 107.21 to 42.27 (P < 0.05). A total of 15 of 86 patients showed more than 75% improvement, 57 patients showed 50–75% improvement, and 14 patients showed 25–50%. After three treatments, all subjects showed improvements in spots, large pores, texture, UV damage, red areas, and porphyrin fluorescence. Pain, erythema, edema, effusion, and scab formation were observed in all patients. The average pain score on a visual analog scale was 6.14 ± 1.12 and all patients tolerated the treatments. The average duration of erythema was 6.26 ± 0.92 days. Hyperpigmentation, hypopigmentation, infections, and worsening of scarring were not seen. All patients were either “very satisfied” or “satisfied” with the treatment outcomes.ConclusionsFractional micro‐plasma radio‐frequency is an effective and safe treatment for acne scars, and might be a good choice for patients with darker skin. Lasers Surg. Med. 50:844–850, 2018. © 2018 Wiley Periodicals, Inc.
A Strategy for Rapid Construction of Blood Vessel‐Like Structures with Complex Cell Alignments
Authors: Wang Nuoxin , Peng Yunhu , Zheng Wenfu , Tang Lixue , Cheng Shiyu , Yang Junchuan , Liu Shaoqin , Zhang Wei , Jiang Xingyu 
Published: April 2018

AbstractA method is developed that can rapidly produce blood vessel‐like structures by bonding cell‐laden electrospinning (ES) films layer by layer using fibrin glue within 90 min. This strategy allows control of cell type, cell orientation, and material composition in separate layers. Furthermore, ES films with thicker fibers (polylactic‐co‐glycolic acid, fiber diameter: ≈3.7 µm) are used as cell‐seeding layers to facilitate the cell in‐growth; those with thinner fibers (polylactic acid, fiber diameter: ≈1.8 µm) are used as outer reinforcing layers to improve the mechanical strength and reduce the liquid leakage of the scaffold. Cells grow, proliferate, and migrate well in the multilayered structure. This design aims at a new type of blood vessel substitute with flexible control of parameters and implementation of functions.
Synthesis of Manganese Oxide Embedded Carbon Nanofibers as Effective Biomimetic Enzymes for Sensitive Detection of Superoxide Anions Released from Living Cells
Authors: Ding Ailing , Liu Feng , Zheng Jiushang , Chen Jiucun , Li Changming , Wang Bin 
Published: April 2018

AbstractCarbon nanofiber/manganese oxide (CNF‐MnO) hybrid nanofibers are synthesized by calcination of potassium permanganate (KMnO4) loaded bacterial cellulose (BC) hydrogels. The chemical structure, morphology, performance, and application of CNF‐MnO aerogels are characterized and studied. The results revealed that MnO nanoparticles are uniformly deposited on the surface of CNF which derived from BC hydrogels. An amperometric superoxide anions (O2•−) sensor is fabricated by the immobilization of the CNF‐MnO aerogels on a glassy carbon electrode, which displays a linear amperometric response with a high sensitivity of 76.2 µA cm−2 × 10−3m−1 and a low detection limit of 1.2 × 10−9m in the concentration range of 5.0 × 10−9m – 2.5 × 10−6m. The successful detection of O2•− released from cancer cells verifies the potential application in biomedical field.