bluuebunny/crossref_metadata_2025_split huggingface dataset:
The plasmatic and salivary levels of IL-1β, IL-18 and IL-6 are associated to emotional difference during stress in young male
Authors: La Fratta I. , Tatangelo R. , Campagna G. , Rizzuto A. , Franceschelli S. , Ferrone A. , Patruno A. , Speranza L. , De Lutiis M. A. , Felaco M. , Grilli A. , Pesce M. 
Published: February 2018

AbstractSaliva collection is considered a non-invasive method to detect inflammatory markers in response to emotional states within natural social contexts. Numerous studies have prompted an important role of cytokines in modulating distinct aspects of social and emotional behavior. The aim of this study was to investigate the reliability of plasma and saliva as investigative tools for measure some inflammatory marker levels (CRP, IL-1β, IL-18, and IL-6). At the same time, the relationships between these markers and emotional states in response to a socio-cognitive stress (Academic Exam, AE), were considered. It was demonstrated that the plasma and saliva concentrations of all immune-mediators analyzed were significantly related across the socio-cognitive stress. In addition, when there was a close correlation to AE, the anger state, the IL-1β, the IL-18 salivary and plasmatic concentrations were significantly higher, while they decreased during the AE. On the other hand, the anxiety state and the IL-6 levels significantly increased throughout the AE. The IL-1β and IL-6 were positively associated to the anger and the anxiety state, respectively. In conclusion, our data highlight that different immune markers are similarly detectable in plasma and saliva during socio-cognitive stress. Also, they could be related to different emotional responses.
Cognitive radio‐enabled Internet of Vehicles: a cooperative spectrum sensing and allocation for vehicular communication
Authors: Eze Joy , Zhang Sijing , Liu Enjie , Eze Elias 
Published: February 2018

Internet of Things (IoTs) era is expected to empower all aspects of Intelligent Transportation System (ITS) to improve transport safety and reduce road accidents. US Federal Communication Commission (FCC) officially allocated 75 MHz spectrum in the 5.9 GHz band to support vehicular communication. The authors studied the application of cognitive radio (CR) technology to IoVs to increase the spectra opportunities for vehicular communication, especially when the allocated 75 MHz is not enough due to high demands because of the increasing number of connected vehicles as already foreseen in the near era of IoVs. They proposed a novel CR Assisted Vehicular NETwork (CRAVNET) framework which empowers CR enabled vehicles to make opportunistic usage of licensed spectrum on the highways. They also developed a novel cooperative three‐state spectrum sensing and allocation model which makes CR vehicular secondary units aware of additional spectrum resources opportunities on their current and future positions, and applies optimal sensing node allocation algorithm to guarantee timely acquisition of the available channels within a limited sensing time. The results of the theoretical analyses and simulation experiments have demonstrated that the proposed model can significantly improve the performance of a cooperative spectrum sensing, and provide vehicles with additional spectrum opportunities.
Fabrication and characterisation of the dye‐sensitised solar cells with the mixture of one‐dimension TiO2 nanorods and graphite nanosheets as the mesoporous scafford
Authors: Lu Junjian , Zhang Min , Luo Fei , Wan Meixiu , Jin Wen , Hu Chuanyue 
Published: February 2018

One‐dimension (1D) TiO2 nanorods (TiO2‐N) has been fabricated via electro‐spinning method. The composites of 1D TiO2‐N and graphite nanosheets, termed as (TiO2‐N/G‐N), have been obtained by the physical doping method. The structure and properties of TiO2‐N and TiO2‐N/G‐N have been characterised by scanning electron microscopy, transmission electron microscopy, X‐ray diffraction, and Raman spectrum. Dye‐sensitised solar cells devices with TiO2 nanoparticles, TiO2‐N and TiO2‐N/G‐N as the mesoporous scaffolds have been developed and investigated, respectively. Device 2 based on TiO2‐N scaffolds showed short‐circuit current (Jsc) of 5.57 mA·cm−1, open‐circuit voltage (VOC) of 0.68 V, filling factor of 0.75, and the power conversion efficiency of 2.85%, respectively. Compared with device 2, device 3 based on TiO2‐N/G‐N exhibited reduced photovoltaic properties.
Synthesis of porous silica materials with tunable morphologies and nanopore sizes using heterogemini surfactants
Authors: Wu Xuanxian , Yi Sili , Li Shuolin , Hou Linxi 
Published: February 2018

A series of heterogemini surfactants C16H33OCH2 CH(OH)CH2N+ (CH3)2 Cn H2n +1 ·Br– were used as the template to synthesise porous silica materials via a Stöber method. The influence of the alkyl chain length of heterogemini surfactants on the morphology of porous silica materials was studied. Porous silica materials were characterised by scanning electron microscopy, transmission electron microscopy and nitrogen adsorption–desorption analysis. Results showed that with the increase of alkyl chain length, the morphologies of porous silica materials gradually transform from sphere to sphere with cavity, sphere composed of vesicles, coral like and finally to lamella. Pore size of materials ranges from 1.17 to 3.93 nm. When the alkyl chain is short enough (n = 8 and 10), a hierarchical pore size distribution can be obtained. The possible formation mechanism of the porous silica materials has been discussed.
Complications of Extended Endoscopic Endonasal Surgery in Elderly Patients
Authors: Kenning Tyler , Pinheiro-Neto Carlos 
Published: February 2018

AbstractExtended endoscopic endonasal procedures are not unique among surgical interventions in carrying increased risk in the elderly population. There are, however, components of the procedure, namely high-flow cerebrospinal fluid leaks, that do result in the potential for increased perioperative morbidity for these patients. We present the case of a 77-year-old male with a large invasive pituitary macroadenoma resected through a transplanum-transtuberculum-transsellar endonasal approach. A gross total resection was obtained with resolution of the patient's preoperative ophthalmologic deficits. One month postoperatively, the patient developed progressive lethargy and cranial imaging demonstrated a left convexity subacute subdural hematoma. This was evacuated through a twist drill craniostomy. Despite measures to limit the operative time of the initial endonasal procedure as well as the absence of a postoperative cerebrospinal fluid fistula, the patient still developed this complication. Along with more typical potential causes of postoperative decline following extended endonasal procedures, problems from high-flow intraoperative cerebrospinal fluid leaks alone can result in morbidity in the elderly population. This should be acknowledged preoperatively and a high suspicion should exist for the presence of intracranial hemorrhage in these patients with any postoperative deficits. Additional intraoperative measures can be utilized to minimize such risks.The link to the video can be found at: https://youtu.be/EkLmt2T8_UE.
Choice of Trial of Labor after Cesarean and Association with Likelihood of Success
Authors: Has Phinnara , Rouse Dwight , Hughes Brenna , Sudhof Leanna 
Published: February 2018

Objective To investigate whether the predicted chance of success is associated with the choice to undergo trial of labor after cesarean (TOLAC).
Study Design Retrospective cohort study of women with a single prior nonelective cesarean delivering a term singleton in 2012 at a tertiary care hospital. A vaginal birth after cesarean (VBAC) score (likelihood of success) was estimated for each patient. The primary outcome was percentage of women choosing TOLAC among women with favorable (> 70% likelihood) and unfavorable VBAC scores. Other factors such as desired sterilization, provider type, and spontaneous labor were included in the analysis.
Results In 2012, 434 women were eligible: 73 with VBAC score >70%, and 361 with score ≤70%. Of those with score >70%, 63% chose TOLAC, compared with 21% with score ≤70% (p < 0.01). In a multivariable analysis, spontaneous labor onset was highly associated with choosing TOLAC: adjusted odds ratio 26.7 (95% confidence interval 13.86–51.29). The choice of TOLAC was also positively associated with resident provider and desired fertility.
Conclusion Almost four in ten women with a history of nonelective primary cesarean and a very high predicted likelihood of VBAC choose elective repeat cesarean. Spontaneous labor was strongly associated with the choice to undergo TOLAC.
All-Inside Single-Bundle Reconstruction of the Anterior Cruciate Ligament with the Anterior Half of the Peroneus Longus Tendon Compared to the Semitendinosus Tendon: A Two-Year Follow-Up Study
Authors: Bi Mingguang , Zhao Chen , Zhang Shuijun , Yao Bin , Hong Zheping , Bi Qing 
Published: February 2018

AbstractThe anterior half of the peroneus longus tendon (AHPLT) has been reported to be acceptable for ligament reconstruction with respect to strength and safety. However, there is little information regarding the clinical outcomes after using the AHPLT compared with other autograft tendons. A prospective randomized controlled study was performed to compare the results of 62 cases of all-inside anatomical single-bundle anterior cruciate ligament (ACL) reconstruction using the AHPLT and 62 cases using semitendinosus graft with an average of 30.0 ± 3.6 months' follow-up. Tunnel placements of enrolled cases were measured on three-dimensional (3D) computed tomography (CT) and X-ray imaging. Knee stability was assessed using the anterior drawer test, pivot shift test, and KT-1000. The International Knee Documentation Committee (IKDC) 2000 subjective score was used to evaluate functional outcomes. The American Orthopedic Foot and Ankle Score (AOFAS) and the assessment of eversion muscle strength were performed to evaluate the function of the ankle donor site. Tunnel positions, which were confirmed with 3D CT, were in the anatomical positions. At the final follow-up, there were no significant differences between the semitendinosus group and the AHPLT group in the IKDC score (90.4 ± 7.1 vs. 89.3. ± 8.4), KT 1000 measurements (1.71 ± 0.57 vs. 1.85 ± 0.77), pivot shift test, and Visual Analogue Scale (VAS) (0.15 ± 0.36 vs. 0.10 ± 0.30). No obvious ankle site complications were found at 24 months. The average AOFAS score of the AHPLT group was comparable to that of the semitendinosus tendon group (99.1 ± 1.40 vs. 99.5 ± 1.21). There was no significant difference in clinical outcomes or knee stability between the semitendinosus group and the AHPLT group at the 2-year follow-up. An AHPLT autograft may be a good alternative for all-inside ACL reconstruction with respect to its strength, safety, and donor site morbidity.
Halt geben
Authors: Pirih Stephanie 
Published: February 2018

Zusammenfassung
Lagerung unter Fototherapie Die Lagerung eines Frühgeborenen ist ein wichtiger Punkt in der Pflege, da
sie unter anderem die Körperselbstwahrnehmung und die Entwicklung fördert. Das Frühgeborene wird mithilfe von
gewickelten Tüchern in einer Art Nest gelagert um Begrenzung zu geben, es wird mit einer Stoffwindel zugedeckt
und trägt evtl. schon Kleidung oder eine Mütze. Frühgeborene, die eine Fototherapie benötigen, werden bis auf
eine Windel nackt und mit weniger Körperbegrenzung gelagert. Dabei kann man beobachten, dass sie deutlich
unruhiger sind und Stresszeichen aufzeigen. Es stellt sich also die Frage, welche Lagerungen und Hilfsmittel
es für Frühgeborene unter Fototherapie gibt, um die Körperbegrenzung zu verbessern und den Stress zu
minimieren.
Combining Various Methods to Assess Insulin Sensitivity in Nonobese Rat after Sleeve Gastrectomy
Authors: Sun Dong , Wang Yanmin , Wei Meng , Zhang Zongli , Hu Sanyuan 
Published: February 2018

Abstract
Background Sleeve gastrectomy (SG) procedure has been proved to improve insulin sensitivity and sustain anti-diabetic effects. Our aim is to co-use several methods to measure insulin sensitivity and investigate the effect of SG on hepatic and peripheral insulin sensitivity at early and long-term stages of postoperation.
Methods Thirty 11-week-old male Goto-Kakizaki rats were divided into SG, sham-operated SG (SOSG), and control groups. They were observed before operation and for 36 weeks of postoperation. Insulin tolerance test (ITT) and homeostasis model of assessment for insulin resistance index(HOMA-IR)were used to measure insulin resistance before operations and at 2 and 36 weeks of postoperation; Pyruvate challenge test (PCT) was administrated to assess the gluconeogenesis capability in order to reflect hepatic insulin sensitivity before operation and at 2 and 36 weeks of postoperation; Hyperinsulinemic euglycemic clamps (HIEC) was conducted before operation and at 2 and 36 weeks of postoperation to calculate the endogenous hepatic glucose production (HGP) at the basal and steady-state for evaluation of hepatic insulin sensitivity, and calculate the exogenous glucose infusion rate (GIR) at the steady-state for evaluation of peripheral insulin sensitivity.
Results The data showed that compared with rats in the sham and control groups, rats in SG group had 1) significantly lower AUCITT, HOMA-IR and AUC PCT values at 2 and 36 weeks of postoperation, 2) lower basal state HGP, but not steady-state GIR at 2 weeks of postoperation, and 3) significantly different basal and steady-state HGP and steady-state GIR at 36 weeks of postoperation. In addition, the basal and steady-state HGP and the steady-state GIR were significantly different between rats in SG group at 2 and 36 weeks of postoperation.
Conclusions This study explored insulin sensitivity of rats after SG by jointly using a variety of techniques. The results showed that SG time-dependently improved the hepatic and peripheral insulin sensitivity.
Saving the dangerous idea: austerity think tank networks in the European Union
Authors: Plehwe Dieter , Neujeffski Moritz , Krämer Werner 
Published: February 2018

Abstract
Austerity has become a key term in economic and social policy debates. Although austerity has been contested both in terms of economic theory and policy-making, it has been remarkably resilient. This resilience has been explained, for example, in structural and institutional terms by the rise of the ‘debt state’. Other explanations have emphasised the strength of austerity ideas rooted in ‘ordo-liberal’ economic theory. Following the insights of science technology scholarship and its emphasis on the social co-production of authoritative knowledge, this article proposes a stronger focus on organisations and their links across nation state borders for an explanation of the stability of austerity capitalism and the thinking underpinning it. The scrutiny of think tank networks, the article proposes, can help bridge the gap between ideational and structural explanations.
Characterisation of tumour‐derived microvesicles in cancer patients' blood and correlation with clinical outcome
Authors: Menck Kerstin , Bleckmann Annalen , Wachter Astrid , Hennies Bianca , Ries Lena , Schulz Matthias , Balkenhol Marko , Pukrop Tobias , Schatlo Bawarjan , Rost Ulrike , Wenzel Dirk , Klemm Florian , Binder Claudia 
Published: February 2018

ABSTRACTTo evaluate whether tumour‐derived microvesicles (T‐MV), originating from the plasma membrane, represent suitable cancer biomarkers, we isolated MV from peripheral blood samples of cancer patients with locally advanced and/or metastatic solid tumours (n = 330, including 79 head & neck cancers, 74 lung cancers, 41 breast cancers, 28 colorectal cancers and 108 with other cancer forms) and controls (n = 103). Whole MV preparations were characterised using flow cytometry. While MV carrying the tumour‐associated proteins MUC1, EGFR and EpCAM were found to be enhanced in a tumour‐subtype‐specific way in patients' blood, expression of the matrix metalloproteinase inducer EMMPRIN was increased independent of tumour type. Higher levels of EMMPRIN+‐MV correlated significantly with poor overall survival, whereas the other markers were prognostic only in specific tumour subgroups. By combining all four tumour‐associated antigens, cancer patients were separated from healthy controls with an AUC of up to 0.85. Ex vivo, whole MV preparations from cancer patients, in contrast to those of controls, induced a tumour‐supporting phenotype in macrophages and increased tumour cell invasion, which was dependent on the highly glycosylated isoform of EMMPRIN. In conclusion, the detection of T‐MV in whole blood, even in minor amounts, is feasible with standard techniques, proves functionally relevant and correlates with clinical outcome.
Deceptive Identity Performance: Offender Moves and Multiple Identities in Online Child Abuse Conversations
Authors: Chiang Emily , Grant Tim 
Published: February 2018

Abstract
This article provides a case study of deceptive online identity performance by a convicted child sex offender. Most prior linguistic and psychological research into online sexual abuse analyses transcripts involving adult decoys posing as children. In contrast, our data comprise genuine online conversations between the offender and 20 victims. Using move analysis (Swales 1981, 1990), we explore the offender’s numerous presented personas. The offender’s use of rhetorical moves is investigated, as is the extent to which the frequency and structure of these moves contribute to and discriminate between the various online personas he adopts. We find from eight frequently adopted personas that two divergent identity positions emerge: the sexual pursuer/aggressor, performed by the majority of his online personas, and the friend/boyfriend, performed by a single persona. Analysis of the offender’s self-describing assertives suggests this distinctive persona shares most attributes with the offender’s ‘home identity’. This article importantly raises the question of whether move analysis might be useful in identifying the ‘offline persona’ in cases where offenders are known to operate multiple online personas in the pursuit of child victims.
The non-convex geometry of low-rank matrix optimization
Authors: Li Qiuwei , Zhu Zhihui , Tang Gongguo 
Published: February 2018

AbstractThis work considers two popular minimization problems: (i) the minimization of a general convex function f(X) with the domain being positive semi-definite matrices, and (ii) the minimization of a general convex function f(X) regularized by the matrix nuclear norm $\|X\|_{*}$ with the domain being general matrices. Despite their optimal statistical performance in the literature, these two optimization problems have a high computational complexity even when solved using tailored fast convex solvers. To develop faster and more scalable algorithms, we follow the proposal of Burer and Monteiro to factor the low-rank variable $X = UU^{\top } $ (for semi-definite matrices) or $X=UV^{\top } $ (for general matrices) and also replace the nuclear norm $\|X\|_{*}$ with $\big(\|U\|_{F}^{2}+\|V\|_{F}^{2}\big)/2$. In spite of the non-convexity of the resulting factored formulations, we prove that each critical point either corresponds to the global optimum of the original convex problems or is a strict saddle where the Hessian matrix has a strictly negative eigenvalue. Such a nice geometric structure of the factored formulations allows many local-search algorithms to find a global optimizer even with random initializations.
Usage and accuracy of medication data from nationwide health information exchange in Quebec, Canada
Authors: Motulsky Aude , Weir Daniala L , Couture Isabelle , Sicotte Claude , Gagnon Marie-Pierre , Buckeridge David L , Tamblyn Robyn 
Published: February 2018

Abstract

Objective
(1) To describe the usage of medication data from the Health Information Exchange (HIE) at the health care system level in the province of Quebec; (2) To assess the accuracy of the medication list obtained from the HIE.

Methods
A descriptive study was conducted utilizing usage data obtained from the Ministry of Health at the individual provider level from January 1 to December 31, 2015. Usage patterns by role, type of site, and tool used to access the HIE were investigated. The list of medications of 111 high risk patients arriving at the emergency department of an academic healthcare center was obtained from the HIE and compared with the list obtained through the medication reconciliation process.

Results
There were 31 022 distinct users accessing the HIE 11 085 653 times in 2015. The vast majority of pharmacists and general practitioners accessed it, compared to a minority of specialists and nurses. The top 1% of users was responsible of 19% of access. Also, 63% of the access was made using the Viewer application, while using a certified electronic medical record application seemed to facilitate usage. Among 111 patients, 71 (64%) had at least one discrepancy between the medication list obtained from the HIE and the reference list.

Conclusions
Early adopters were mostly in primary care settings, and were accessing it more frequently when using a certified electronic medical record. Further work is needed to investigate how to resolve accuracy issues with the medication list and how certain tools provide different features.
Sexually Transmitted Infections Among HIV-Infected Individuals in the District of Columbia and Estimated HIV Transmission Risk: Data From the DC Cohort
Authors: Lucar Jose , Hart Rachel , Rayeed Nabil , Terzian Arpi , Weintrob Amy , Siegel Marc , Parenti David M , Squires Leah E , Williams Rush , Castel Amanda D , Benator Debra A ,   DC Cohort Executive Committee, Hays Harlen , Binkley Jeffrey , Hart Rachel , Franklin Dana , Rayeed Nabil , Taylor Rob , Hou Qingjiang , Subramanian Thilakavathy , D’Angelo Lawrence , Rahkmanina Natella , Kharfen Michael , Wood Angela , Kumar Princy , Parenti David , Greenberg Alan , Castel Amanda , Young Heather , Peterson James , Happ Lindsey Powers , Jaurretche Maria , Doshi Saumil , Rana Sohail , Fernandez Ricardo , Hebou Annick , Dieffenbach Carl , Masur Henry , Abbott Stephen , Benator Debra , Ruiz Maria Elena , Elio Rick 
Published: February 2018

AbstractBackgroundWashington, DC, has one of the highest rates of HIV infection in the United States. Sexual intercourse is the leading mode of HIV transmission, and sexually transmitted infections (STIs) are a risk factor for HIV acquisition and transmission.MethodsWe evaluated the incidence and demographic factors associated with chlamydia, gonorrhea, and syphilis among HIV-infected persons enrolled at 13 DC Cohort sites from 2011 to 2015. Using Poisson regression, we assessed covariates of risk for incident STIs. We also examined HIV viral loads (VLs) at the time of STI diagnosis as a proxy for HIV transmission risk.ResultsSix point seven percent (451/6672) developed an incident STI during a median follow-up of 32.5 months (4% chlamydia, 3% gonorrhea, 2% syphilis); 30% of participants had 2 or more STI episodes. The incidence rate of any STIs was 3.8 cases per 100 person-years (95% confidence interval [CI], 3.5–4.1); age 18–34 years, 10.8 (95% CI, 9.7–12.0); transgender women, 9.9 (95% CI, 6.9–14.0); Hispanics, 9.2 (95% CI, 7.2–11.8); and men who have sex with men (MSM), 7.7 (95% CI, 7.1–8.4). Multivariate Poisson regression showed younger age, Hispanic ethnicity, MSM risk, and higher nadir CD4 counts to be strongly associated with STIs. Among those with an STI, 41.8% had a detectable VL within 1 month of STI diagnosis, and 14.6% had a VL ≥1500 copies/mL.ConclusionsSTIs are highly prevalent among HIV-infected persons receiving care in DC. HIV transmission risk is considerable at the time of STI diagnosis. Interventions toward risk reduction, antiretroviral therapy adherence, and HIV virologic suppression are critical at the time of STI evaluation.