bluuebunny/crossref_metadata_2025_split huggingface dataset:
HLA-DRB1 Amino Acid Positions and Residues Associated with Antibody-positive Rheumatoid Arthritis in Black South Africans
Authors: Govind Nimmisha , Reynolds Richard J. , Hodkinson Bridget , Ickinger Claudia , Ramsay Michele , Bridges S. Louis , Tikly Mohammed 
Published: November 2018

Objective.To investigate the association of specific amino acid positions, residues, and haplotypes of HLA-DRB1 in black South Africans with autoantibody-positive rheumatoid arthritis (RA).Methods.High-resolutionHLA-DRB1genotyping was performed in 266 black South Africans with autoantibody-positive RA and 362 ethnically and geographically matched controls. The alleles were converted to specific amino acid residues at polymorphic sites for downstream analyses. Logistic regression models were used to test whether variability at site, specific amino acid residues, and haplotypes (constructed from positions 11, 71, and 74) were associated with RA.Results.Of the 29 amino acid positions examined, positions 11, 13, and 33 (permutation p = 3.4e-26, 1.2e-27, and 2.1e-28, respectively) showed the strongest association with RA. Univariate analyses of individual amino acid residues showed valine at position 11 (OR 5.1, 95% CI 3.7–7.0) and histidine at position 13 (OR 6.1, 95% CI 4.2–8.6) conferred the highest risk. The valine containing haplotypes of position 11, 71, 74, V_K_A conferred the most risk (OR 4.52, 95% CI 2.68–7.61) and conversely the haplotype with serine at this position, S_K_R, conferred the most protection (OR 0.83, 95% CI 0.61–1.15).Conclusion.Autoantibody-positive RA in black South Africans is associated with histidine at position 13 and valine at position 11 of HLA-DRB1, and haplotypes with valine at position 11 conferred the highest risk; conversely, serine at position 11 conveyed protection.
Using Acute-phase Reactants to Inform the Development of Instruments for the Updated Psoriatic Arthritis Core Outcome Measurement Set
Authors: Elmamoun Musaab , Leung Ying Ying , O’Sullivan Denis , Steinkoenig Ingrid , Chandran Vinod , Gladman Dafna D. , FitzGerald Oliver M. , Orbai Ana-Maria , Eder Lihi 
Published: November 2018

Objective.Systemic inflammationˆ is assessed through measurement of acute-phase reactants such as C-reactive protein (CRP) and erythrocyte sedimentation rate (ESR). With few exceptions, most randomized controlled trials (RCT) have assessed acute-phase reactants (CRP and ESR) as part of the American College of Rheumatology (ACR) 20 response criteria. As part of the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA)–Outcome Measures in Rheumatology (OMERACT) working group, we performed a systematic review of the literature to assess the performance of inflammatory biomarkers in psoriatic arthritis (PsA).Methods.A systematic search of PubMed and Embase was performed. The search included peer-reviewed articles and scientific meeting abstracts about RCT and longitudinal observational studies that assessed systemic inflammation using acute-phase reactants in PsA. Studies were assessed following the components of the OMERACT filter including construct validity, responsiveness, and predictive validity.Results.There were 2764 articles retrieved, and 71 articles were included for this systematic review. Twenty-eight articles reported CRP and/or ESR separately, and the remaining articles reported CRP and/or ESR as part of the ACR response criteria. Studies assessing OMERACT responsiveness provided conflicting reports. Inflammatory biomarkers had construct validity for more active disease. Evidence suggests that an elevation of ESR predicts cardiovascular outcomes.Conclusion.Data regarding assessment of systemic inflammation using acute-phase reactants (CRP and ESR) are limited. There is only weak evidence to support normalization of these biomarkers in predicting good clinical outcomes/remission criteria. The predictive value for cardiovascular outcomes was generally good. Further studies to assess systemic inflammation in PsA using acute-phase reactants and other laboratory biomarkers are needed.
Identifying Persons with Axial Spondyloarthritis At Risk of Poor Work Outcome: Results from the British Society for Rheumatology Biologics Register
Authors: Macfarlane Gary J. , Shim Joanna , Jones Gareth T. , Walker-Bone Karen , Pathan Ejaz , Dean Linda E. 
Published: November 2018

Objective.First, to test the hypothesis that, among working patients with axial spondyloarthritis (axSpA), those who report issues with reduced productivity at work (presenteeism) are at higher risk of work absence (absenteeism), and patients who report absenteeism are at higher risk of subsequently leaving the workforce. Second, to identify characteristics of workers at high risk of poor work outcome.Methods.The British Society for Rheumatology Biologics Register in Ankylosing Spondylitis has recruited patients meeting Assessment of Spondyloarthritis international Society criteria for axSpA from 83 centers. Data collection involved clinical and patient-reported measures at recruitment and annually thereafter, including the Work Productivity and Activity Impairment scale. Generalized estimating equations were used to identify factors associated with poor work outcomes.Results.Of the 1188 participants in this analysis who were working at recruitment, 79% reported some presenteeism and 19% some absenteeism in the past week owing to their axSpA. Leaving employment was most strongly associated with previous absenteeism (RR 1.02 per % increase in absenteeism, 95% CI 1.01–1.03), which itself was most strongly associated with previous presenteeism, a labor-intensive job, and peripheral joint involvement. High disease activity, fatigue, a labor-intensive job, and poorer physical function were all independently associated with future presenteeism.Conclusion.Clinical and patient-reported factors along with aspects of work are associated with an increased risk of axSpA patients having a poor outcome in relation to work. This study has identified modifiable factors as targets, facilitating patients with axSpA to remain productive at work.
Autonomie masculine, précarité féminine. Les représentant·e·s de commerce face au salaire à la commission
Authors: Bernard Sophie 
Published: November 2018

Cet article se focalise sur le cas des représentant·e·s de commerce payés à la commission. Ces salariés ont pour spécificités de bénéficier d’une forte autonomie et d’être soumis à une incertitude salariale qui tendent à les rapprocher des travailleurs indépendants. En découlent des pratiques professionnelles et un rapport au travail distincts entre hommes et femmes. Alors que les premiers voient l’autonomie au travail comme une opportunité de s’investir intensément au travail dans le but de gagner des salaires élevés pour assurer leur promotion sociale, les femmes s’en saisissent quant à elles pour « concilier » vie professionnelle et vie familiale, ce qui leur permet un maintien et un retour en emploi. Ces différences reposent sur des « arrangements de couple » qui participent in fine au renforcement des inégalités de genre, confortant les hommes dans le statut de « Monsieur Gagne-pain » et les femmes dans celui de « Madame Gagne-petit ».
Regard diachronique et prospectif sur un demi-siècle de traductologie pragmatique
Authors: Lavault-Olléon Élisabeth 
Published: November 2018

Depuis la création du néologisme « traductologie » en 1968, la traductologie a progressivement acquis son autonomie comme discipline universitaire et a considérablement prospéré, foisonnant en une multitude d’approches théoriques et appliquées tout en se nourrissant des apports d’autres sciences humaines. Nous nous inscrivons dans la thématique diachronique du présent numéro d’ASp en retraçant les grandes étapes de ce parcours de cinquante ans et plus dans une perspective pragmatique. Nous abordons ensuite les approches des dernières années et leur évolution incertaine en lien avec la traduction automatique.
Infestation and timing of use of non-crop plants by Drosophila suzukii (Matsumura) (Diptera: Drosophilidae) in the Okanagan Basin, Canada
Authors: Thistlewood Howard M.A. , Rozema Brigitte , Acheampong Susanna 
Published: November 2018

AbstractDrosophila suzukii (Matsumura) (Diptera: Drosophilidae), was first detected in 2009 in the Okanagan Basin, British Columbia, Canada. During 2010–2016, 94 570 fruits of 35 non-crop species, from 12 plant families, were collected from 101 sites where adult D. suzukii flies were trapped, and incubated in a controlled environment. In total, 450 adult D. suzukii emerged from 62 of 929 fruit collections, and from 10 host plant species in five families, of which six species are native to the region. Five plant species are reported for the first time as hosts of D. suzukii, and 11 species for the first time as non-hosts. Measures of fly occurrence and infestation reveal it to be relatively abundant in five hosts and low in others. The fly reproduced in a succession of host plants, with first infestation of each from mid-July through mid-September, and was present until mid-October, but overwintering stages were not found. Degree-day accumulations for the infested period suggest that three to five generations of D. suzukii developed on non-crop plants and formed a large contribution to the annual increases observed in trap counts in a semi-arid cold winter climate, with implications for many strategies of pest management.
Chlorantraniliprole impact on survival and progeny quality of the pupa of the parasitoid Palmistichus elaeisis (Hymenoptera: Eulophidae)
Authors: de Sousa Pereira Kleber , Chediak Mateus , Zanuncio José Cola , Guedes Raul Narciso Carvalho 
Published: November 2018

AbstractThe insecticide chlorantraniliprole is recommended for integrated pest management programmes of caterpillar (Lepidoptera) pest species. This insecticide is considered harmless to parasitoids, but its selectivity may vary with the species of natural enemy, few of which were subjected to testing. Furthermore, in addition to the active ingredient, formulation adjuvants may improve insecticide efficiency, but also its impact on nontargeted organisms. Here the chlorantraniliprole effect and its interaction with adjuvant on the survival and qualitative parameters of progeny of the nontarget parasitoid Palmistichus elaeisis (Delvare and LaSalle) (Hymenoptera: Eulophidae) were studied. The treatments used were: chrolantraniliprole (T1), chlorantraniliprole+surfactant (T2), and deionised water (T3, control). Pupae of Diaphania hyalinata Linnaeus (Lepidoptera: Crambidae) were subjected to these treatments for 24 hours and offered to the adult parasitoids. Chlorantraniliprole and chlorantraniliprole+surfactant did not elicit direct toxicity to female parasitoids. However, chlorantraniliprole and its combination with surfactant reduced the head capsule width of the female progeny. This insecticide alone also reduced emergence and the progeny metatibia length. Chlorantraniliprole did not induce mortality of P. elaeisis adults, but its negative impact on the emergence and progeny size of this parasitoid suggests an important sublethal effect to be considered.
On Animals
Authors: Clough David L. 
Published: November 2018

This book presents an authoritative and comprehensive survey of human practice in relation to other animals, together with a Christian ethical analysis building on the theological account of animals which David Clough developed in On Animals Volume I: Systematic Theology (2012). It argues that a Christian understanding of other animals has radical implications for their treatment by humans, with the human use and abuse of non-human animals for food the most urgent immediate priority.
Following an introduction examining the task of theological ethics in relation to non-human animals and the way it relates to other accounts of animal ethics, this book surveys and assess the use humans make of other animals for food, for clothing, for labour, as research subjects, for sport and entertainment, as pets or companions, and human impacts on wild animals. The result is both a state-of-the-art account of what humans are doing to other animals, and a persuasive argument that Christians in particular have strong faith-based reasons to acknowledge the significance of the issues raised and change their practice in response.
Promoting metalinguistic awareness in a classroom to improve reading comprehension: Examples from Roald Dahl’s novel The BFG
Authors: Sinar Beck 
Published: November 2018

It is widely recognised that successful reading involves the interaction of a number of different cognitive skills and strategies in order to achieve compre-hension of the text (Baker, 2002). These skills and strategies are generally considered to be controlled by a global process called ‘metacognition’ (Kuhn & Dean, 2004). In this paper, I suggest that a large part of metacognition when reading has a (meta)linguistic component and hence time should be devoted to raising (meta)linguistic awareness when teaching and honing reading skills and strategies. Tasks based around a short extract from Roald Dahl’s (1982[2013]) novel The BFG are presented and discussed in order to illustrate how metalinguistic awareness might be raised in a classroom. Such tasks not only help to improve reading comprehension but have a number of additional benefits: they enhance and support the metacognitive toolkit, improve vocabulary acquisition and growth, and can bring a love of language and the fun of language play into the classroom.Keywords: metalinguistic awareness, reading comprehension, vocabulary, classroom activities, Roald DahlÅ fremme metalingvistisk bevissthet i et klasserom for å forbedre leseforståelse: eksempler fra Roald Dahls roman The BFGSammendragDet er bred enighet om at vellykket lesing trekker veksler på flere forskjellige kognitive ferdigheter og strategier tilknyttet tekstforståelse (Baker, 2002). Disse ferdighetene og strategiene hører inn under den globale prosessen ‘metakog-nisjon’ (Kuhn & Dean, 2004). I denne artikkelen argumenterer jeg for at en stor del av metakognisjonen i lesing har en (meta)lingvistisk komponent, og følgelig at tid bør vies til å utvikle (meta)lingvistisk bevissthet i undervisningen av leseferdigheter og strategier. Arbeidsoppaver basert på et kort utdrag fra Roald Dahls (1982[2013]) The BFG (The Big Friendly Giant / SVK – Store Vennlige Kjempe) presenteres og diskuteres for å illustrere hvordan metalingvistisk bevissthet kan utvikles i klasserommet. Slike arbeidsoppgaver hjelper ikke bare med å forbedre leseforståelsen, men har også flere andre fordeler: de forsterker og støtter den metakognitive verktøykassen, forbedrer både innlæring og utvidelse av ordforrådet, kan øke språkgleden og oppmuntre til lek med språk i klasserommet.Nøkkelord: metalingvistisk bevissthet, leseforståelse, vokabular, klasseroms-aktiviteter, Roald Dahl
Prevalence and Correlates of Body Image Dissatisfaction in Patients with Multiple Sclerosis
Authors: Stevens Serena D. , Thompson Nicolas R. , Sullivan Amy B. 
Published: November 2018

Abstract

Background:
Body image dissatisfaction (BID) strongly predicts undesirable outcomes, including disordered eating, depression, and low self-esteem. People with multiple sclerosis (MS) may have higher BID due to changes in mobility and functioning and high rates of depression; however, little research has explored BID in people with MS. Identifying factors predicting BID in people with MS would help providers become more aware of BID and its possible negative outcomes.

Methods:
The sample included 151 adult patients with MS receiving care at the Cleveland Clinic Mellen Center for MS. The Body Shape Questionnaire was administered, and demographic information was collected from medical records. Data on MS-specific variables were collected via computerized testing. A one-sample t test, an independent-samples t test, and a hierarchical linear regression were conducted.

Results:
Average scores on BID were not significantly different from the population mean. Patients with moderate/marked concern were more likely to be female and had higher body mass index values, Patient Health Questionnaire-9 scores, and Quality of Life in Neurological Disorders Stigma T-scores. There were no age differences. No MS-specific variables significantly predicted BID.

Conclusions:
People with MS show approximately the same levels of BID as the general population. Higher BID was associated with being female and with higher body mass index, depression, and stigma. No MS-specific variables predicted higher BID after controlling for significant variables. Given the evidence in the literature of the negative effects of BID on health behaviors and mood, it is important to explore whether other factors affect BID in people with MS.
Foreword
Authors: Zigmunde Alīda 
Published: November 2018

The second volume of the scientific journal of RTU Research Centre for Engineering History (RCEH) is devoted to the 100th anniversary of the Republic of Latvia. The authors of articles are historians of science, pedagogues and museum workers of Latvia, Lithuania and Ukraine. The themes of articles and their main characters are related to the Riga Polytechnicum (RP) / Riga Polytechnic Institute (RPI).
Professional activities of Latvian born Lithuanian architect and engineer Karolis Reisonas (1894–1981) in Šiauliai
Authors: Saladžinskas Sigitas Vladas , Vaisvalavičiene Kristina 
Published: November 2018

The article introduces the life of not well-known in Latvia Latvian born Lithuanian Karolis Reisonas (in Latvian: Kārlis Reisons; 1894–1981) and his professional activities in Šiauliai city, as well as highlights the main features of the architect’s creative work and the importance of his work in the history of Lithuanian architecture. K. Reisonas was one of the most prominent creators of modern architecture of the 20th century during interwar period in Lithuania. He is the author and co-author of representative buildings in the cities of Lithuania, as well as in Riga and Adelaide (Australia). K. Reisonas graduated from Riga Real School (1913) and St. Petersburg Institute of Civil Engineers (1920). He has worked as the Engineer of the Šiauliai city and Head of the Construction Department of the Municipality (1922–1930), the Director of the Tenth1 Courses of Šiauliai Construction (1925), later – the Director of the Šiauliai Vocational School (1926), and an Advisor of Lithuania Chamber of Agriculture (1927–1928). Fourteen building to his design in Kaunas and Šiauliai cities are included in the list of cultural values of Lithuania. K. Reisonas’ early projects are characterized by historicism, eclectic elements, of «brick style». Later projects have the features of aesthetic rationalism, functionalism, and adaptation to urban and cultural-historical context. After the Second World War, he and his family immigrated to Germany, later Adelaide in Australia, where he participated in the life of the Adelaide Lithuanian community.
Vēsturisko mūrjavu ilgmūžības nodrošināšana Latvijas senatnes būvēs
Authors: Kiriloviča Inta , Karpe Margarita , Vītiņa Inta , Igaune-Blumberga Silvija 
Published: November 2018

Pētījumi par Latvijas kultūrvēsturisko ēku akmens materiālu koroziju kopš 1984. g. tiek veikti Rīgas Tehniskās universitātes Silikātu materiālu institūta Akmens materiālu konservācijas un restaurācijas centrā. Šie pētījumi sniedz bagātīgu materiālu krājumu un pieredzi saistībā ar senatnes būvju ilgmūžības nodrošināšanu. Katra objekta restaurācijas tehnoloģijas izstrādes pamatā ir jābūt rūpīgai izpētei. Līdzšinējā pieredze ir devusi vērtīgas atziņas par mūsdienās pieejamo javu saistvielu (portlandcementa, kaļķu u. c.) izmantošanas nosacījumiem restaurācijas procesos.Ensuring the Permanence of Historical Mortars within Buildings of LatviaSince 1984 research on corrosion of cultural heritage buildings of Latvia has been conducted in the Centre of Restoration and Conservation of Stone Materials, Institute of Silicate Materials, Riga Technical University. This research provides a wide collection of materials and experience in ensuring the permanence of historical buildings. Accurate investigations must be a fundamental part of the restoration technology of each object. The acquired experience has given valuable knowledge about the aspects of use of different binders (Portland cement, lime etc.) in restoration processes.Keywords – lime, corrosion, mortar, restoration, Roman cement, binder, salts
Prionochelys matutinaZangerl, 1953 (Testudines: Pan-Cheloniidae) from the Late Cretaceous of the United States and the evolution of epithecal ossifications in marine turtles
Authors: Gentry Andrew D. 
Published: November 2018

BackgroundMany neritic to nearshore species of marine adapted turtle from the Late Cretaceous of North America are thought to represent the stem lineage of Cheloniidae but due to fragmentary holotypes, low total specimen counts, and resultantly incomplete morphological character suites, are routinely placed either within or outside of crown group Chelonioidea leaving their precise cladistic affinities uncertain. Despite this systematic ambiguity, the referral of these species to either the stem of Cheloniidae or Chelonioidea belies the critical importance of these taxa in any investigation into the origins of extant marine turtles. The adequate incorporation of these species into phylogenetic studies requires the formal description of relatively complete specimens, particularly those possessing associated cranial and post-cranial material.MethodsRemarkably complete fossil specimens of several adult and juvenile marine turtles from the Mooreville Chalk and Eutaw Formations (Alabama, USA) are formally described and assigned toPrionochelys matutina. This material provides new information into the anatomy, ontogeny, and cladistic affinities of the species. A phylogenetic hypothesis for Late Cretaceous marine turtles is then generated through the consilience of stratigraphic, morphological, and molecular data.ResultsPhylogenetic analysis placesPrionochelys matutinaon the stem of Cheloniidae as a member of a monophyletic clade with other putative pan-cheloniids, includingCtenochelys stenoporus,Ctenochelys acris,Peritresius martini, andPeritresius ornatus. The members of this clade possess incipient secondary palates, pronounced carapacial and plastral fontanelles at all stages of development, and are characterized by the presence of superficial ossifications at the apices of the neural keel elevations along the dorsal midline of the carapace.DiscussionThe epithecal osteoderms dorsal to the neural series (epineurals) found in Ctenochelyidae are unique among turtles. The presence of epineurals in ctenochelyid turtles shows that epithecal ossifications arose independently in both leatherback (Dermochelyidae) and hard-shelled (Cheloniidae) marine turtles. Whether or not the epineurals of Ctenochelyidae are homologous with the dermal ossicles comprising the carapace ofDermochelys coriacearemains untested however, histological thin sectioning of dermochelyid and ctenochelyd epithecal elements may reveal meaningful information in future studies.