bluuebunny/crossref_metadata_2025_split huggingface dataset:
Corporação, espaço e organização reticular: notas conceituais
Authors: Oliveira Fernando Fernandes de 
Published: November 2018

Resumo
As corporações exercem evidente papel ante a estruturação espacial no capitalismo. Tal racionalidade perpassa pela incessante busca por difusão das condições produtivas indispensáveis à reprodução dos capitais numa escala ampliada de ação. O presente ensaio busca resgatar criticamente uma abordagem de estudos econômicos e geográficos que tiveram importância no entendimento da relação entre corporação, espaço, organização em rede e dos laços político-econômicos atados junto ao aparato institucional do Estado. Mira, nessa condição, dar continuidade aos amparos teóricos que visam conferir inteligibilidade para as tramas espaciais da grande corporação, assim compreendida como objeto de apreciação da Geografia.
Palavras-chave: Corporação multilocalizada, estrutura organizacional, redes, Estado.

Abstract
The corporations exert an apparent role regarding the spatial organization of capitalism. Such rationality passes through the unceasing search for diffusion of the productive conditions indispensable to the reproduction of capital in an extended action scale. The present paper seeks to redeem critically an approach of economic and geographic studies which had importance in the understanding of the relation among corporation, space, network organization and political-economic ties bound along with the State institutional apparatus. Aiming, in this condition, to give continuity to the theoretical support which aims at granting intelligibility for spatial plots of the great corporation, thus understood as Geography’s subject of appreciation.
Keywords: Multi-local corporation, organizational structure, networks, State.

Résumé
Les corporations exercent un rôle évident devant la structuration spatiale au capitalisme. Telle rationalité traverse l’incessante recherche de diffusion des conditions productives indispensables à la reproduction du capital dans une échelle agrandie d’action. Le présent essai a comme objectif récupérer, de façon critique, une approche d’études économiques et géographiques qui ont joué un rôle important dans l’entendement de la relation entre la corporation, l’espace, l’organisation en réseau et les liens politico-économiques attachés à l’appareil institutionnel d’État. Il vise, sous cette condition, poursuivre les supports théoriques qui confèrent l’intelligibilité aux relations spatiales de la grande corporation, ainsi comprise comme objet d’appréciation de la Géographie.
Mots clé: Corporation multi localisée, structure organisationnelle, réseaux, État.
O Carste e o Geopatrimônio em Júlio Verne: o exemplo de Mathias Sandorf
Authors: Travassos Luiz Eduardo Panisset , Silva Glaycon de Souza Andrade e , Borges Felipe de Ávila Chaves 
Published: November 2018

Resumo
As cavernas e as paisagens nas quais estão inseridas têm povoado o imaginário coletivo de diversas culturas, seja por meio de lendas e mitos de criação, seja por fazerem parte do cenário de relatos de viagem ou romances. Assim sendo, a pesquisa tem por finalidade demonstrar de que forma o Carste Dinárico e a Pazinska Jama são retratados no livro Mathias Sandorf, de Júlio Verne. A análise foi desenvolvida de maneira associativa aos conceitos tanto da Carstologia, quanto da Espeleologia a fim de identificar no texto de Júlio Verne sua contribuição para demonstrar aos leitores aspectos da geografia física do carste. Para que o objetivo fosse atingido, os autores analisaram a narrativa do autor, bem como pesquisaram os aspectos da geomorfologia cárstica. Os resultados apontaram para a união entre ficção e realidade favorecendo, inclusive, pesquisas científicas após a publicação do livro.
Palavras-chave: Júlio Verne; Carste; Geopatrimônio.

Abstract
Caves and the landscapes in which they are present have populated the collective imaginary of diverse cultures, either through legends and myths of creation, or because they are part of the scenario of travel reports or novels. Thus, the research aims to demonstrate how the Dinaric Karst and the Pazinska Jama are portrayed in the book Mathias Sandorf, by Jules Verne. The analysis was developed in an associative way to the concepts of both Karstology and Speleology in order to identify in the text of Verne his contribution to demonstrate to the reader’s aspects of the physical geography of karst. In order to reach the objective, the authors analyzed the narrative of the author as well as researched aspects of karst geomorphology. The results pointed to the union between fiction and reality even favoring scientific research after the publication of the book.
Keywords: Jules Verne; Karst; Geoheritage.

Résumé
Les grottes et les paysages dans lesquels elles s'insèrent ont peuplé l'imaginaire collectif de diverses cultures, soit à travers les légendes et les mythes de la création, soit parce qu'elles font partie du scénario des récits de voyage ou des romans. Par conséquent, ce travail a pour but de montrer comment le karst dinarique et le Pazinska Jama sont représentés dans le livre 'Mathias Sandorf', de Jules Verne.L'analyse a été développée de manière associative aux concepts de karstologie et de spéléologie afin d'identifier dans le texte de Jules Verne sa contribution à démontrer aux lecteurs des aspects de la géographie physique du karst. Afin d'atteindre cet objectif, les auteurs ont analysé le récit de Verne et ont également étudié des aspects de la géomorphologie karstique. Les résultats ont mis en évidence l'union entre la fiction et la réalité, favorisant même la recherche scientifique après la publication du livre.
Mots-clés: Jules Verne; Karst; Geoheritage.
De volta às discussões sobre o significado de paisagem e outras avenças
Authors: Santos Douglas 
Published: November 2018

Resumo
Acompanhando as proposições metafísicas que sobrecarregam o discurso geográfico e, certamente, nossas noções de paisagem, este artigo dialogando com um conjunto de citações disponibilizado pelo professor e amigo Nicolás Ortega Cantero, em uma das aulas ministrada na Universidade Autônoma de Madri, é uma revisita ao tema – lembrando que os artigos que já publiquei sobre o assunto se encontram identificados na bibliografia.
Palavras-chave: Geografia, teoria e método, paisagem, território, região.

Abstract
Following the metaphysical propositions that overload the geographical discourse and, certainly, our conceptions of landscape, this paper is a revisit to the theme and dialogues with a set of quotes, provided by the friend and professor Nicolás Ortega Cantero, in one of his classes given at the Autonomous University of Madrid – remember, the articles I have already published about the subject are identified in the bibliography.
Keywords: Geography; theory and method; landscape; territory; region

Resumen
En el marco de las propuestas metafísicas que sobrecargan el discurso geográfico y, por supuesto, nuestras nociones de paisaje, este artículo, dialogando con un conjunto de citas ofrecido por el profesor y amigo Nicolás Ortega Cantero, en una de sus clases en la Universidad Autónoma de Madrid, es una revisita al tema - recordando que los artículos que ya he publicado sobre el tema se encuentran identificados en la bibliografía.
Palabras clave: Geografía, teoría y método, paisaje, territorio, región.
Distribuição espacial dos casos de intoxicação por agrotóxicos agrícolas em diferentes monocultivos no estado de Goiás (2005-2015)
Authors: Neves Pedro Dias Mangolini , Mendonça Marcelo Rodrigues 
Published: November 2018

Resumo
Os impactos do uso de agrotóxicos sobre o ambiente e a saúde humana têm merecido a atenção da comunidade científica no Brasil e, precisamente em Goiás, considerado um dos “celeiros agrícolas do país” nas últimas décadas. Neste artigo foram sistematizados e apresentados dados de intoxicação por agrotóxicos, no período de 2005 a 2015, estado de Goiás obtidos no Centro de Informação Toxicológica – CIT/GO, que guarda as fichas de notificação compulsória de intoxicações por agrotóxicos, lotado na Superintendência de Vigilância Sanitária e Ambiental - SUVISA de Goiás. Na análise da presença de monocultivos nos municípios, pode-se perceber uma relação perigosa entre o elevado número total de intoxicações por habitantes e a territorialização do agronegócio, principalmente, o cultivo de soja, milho e cana-de-açúcar.
Palavras-chave: Intoxicação; Agrotóxicos; Commodities agrícolas; Goiás.

Abstract
The impacts of the use of agrochemicals on the environment and human health have deserved the attention of the scientific community in Brazil and, in Goiás, considered one of the "agricultural barns of the country" in the last decades. In this article, pesticide intoxication data were systematized and presented in the period from 2005 to 2015, state of Goiás, obtained at the Center for Toxicological Information - CIT/GO), which keeps the compulsory notification of poisoning by pesticides, filled at the Superintendence of Surveillance Sanitary and Environmental - SUVISA of Goiás. In the analysis of the presence of monocultures in the municipalities, one can perceive a dangerous relationship between the high total number of intoxications per inhabitant and the territorialization of agribusiness, mainly soybean, corn and sugar cane cultivation.
Keywords: Intoxication; Pesticides; Agricultural commodities; Goiás.

Resumen
Los impactos del uso de agrotóxicos sobre el ambiente y la salud humana han merecido atención de la comunidad científica en Brasil y, precisamente en Goiás, considerado uno de los "graneros agrícolas del país" en las últimas décadas. En este artículo se sistematizaron y presentaron datos de intoxicación por agrotóxicos, en el período de 2005 a 2015, estado de Goiás obtenidos en el Centro de Información Toxicológica - CIT/GO, que guarda las fichas de notificación obligatoria de intoxicaciones por agrotóxicos, abarrotado en la Superintendencia de Vigilancia Sanitaria y Ambiental - SUVISA de Goiás. En el análisis de la presencia de monocultivos en los municipios, se puede percibir una relación peligrosa entre el elevado número total de intoxicaciones por habitantes y la territorialización del agronegocio, principalmente, el cultivo de soja, maíz y caña de azúcar.
Palabras clave: Intoxicación; plaguicidas; Productos agrícolas; Goiás.
Magnetotransport Anomaly in Room‐Temperature Ferrimagnetic NiCo2O4 Thin Films
Authors: Chen Xuegang , Zhang Xiaozhe , Han Myung‐Geun , Zhang Le , Zhu Yimei , Xu Xiaoshan , Hong Xia 
Published: November 2018

AbstractThe inverse spinel ferrimagnetic NiCo2O4 presents a unique model system for studying the competing effects of crystalline fields, magnetic exchange, and various types of chemical and lattice disorder on the electronic and magnetic states. Here, magnetotransport anomalies in high‐quality epitaxial NiCo2O4 thin films resulting from the complex energy landscape are reported. A strong out‐of‐plane magnetic anisotropy, linear magnetoresistance, and robust anomalous Hall effect above 300 K are observed in 5–30 unit cell NiCo2O4 films. The anomalous Hall resistance exhibits a nonmonotonic temperature dependence that peaks around room temperature, and reverses its sign at low temperature in films thinner than 20 unit cells. The scaling relation between the anomalous Hall conductivity and longitudinal conductivity reveals the intricate interplay between the spin‐dependent impurity scattering, band intrinsic Berry phase effect, and electron correlation. This study provides important insights into the functional design of NiCo2O4 for developing spinel‐based spintronic applications.
Synthesis of functionalized magnetic nanoparticles as a nanocarrier for targeted drug delivery
Authors: Ahmad Panahi Homayon , Nourbakhsh Sogol , Siami Fatemeh 
Published: November 2018

AbstractIn this research, iron oxide magnetic nanoparticles (NPs) were synthesized by chemical co‐precipitation method. The surface of particles was grafted with β‐cyclodextrin/N,N‐dimethylacrylamide (β‐CD/DMAA) copolymer. Potency of NPs as carrier of antibiotic ofloxacin (OFL) was evaluated. They were characterized by scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, elemental analysis, and thermogravimetric analysis. The effect of the adsorption parameters such as pH, contact time, and temperature for sorption of drug onto NPs was evaluated and optimized. The drug release profile showed that approximately 60% of the adsorbed drug was released in the first 10 min at pH of 1.2 (simulated gastric fluid) and 55% was released within 30 hr in pH of 7.4 (simulated intestinal fluid). Findings of study suggested the suitability of β‐CD/DMAA grafted magnetic NPs for OFL delivery.
Resveratrol inhibits Src tyrosine kinase, STAT3, and Wnt signaling pathway in collagen induced arthritis model
Authors: Oz Burak , Yildirim Ahmet , Yolbas Servet , Celik Zulfinaz Betul , Etem Ebru Onalan , Deniz Gulnihal , Akin Mustafa , Akar Zeynel Abidin , Karatas Ahmet , Koca Suleyman Serdar 
Published: November 2018

AbstractResveratrol, a phytochemical, acts several cellular signaling pathways and has anti‐inflammatory potentials. The purpose of this study is to research the therapeutic effect of resveratrol in collagen‐induced arthritis (CIA) model in rats and whether resveratrol affects the activities of signaling pathways those are potent pathogenic actors of rheumatoid arthritis. Arthritis was induced by intradermal injection of chicken type II collagen combined with incomplete Freund's adjuvant in Wistar albino rats. One day after the onset of arthritis (day 14), resveratrol (20 mg/kg/day) was given via oral gavage, until day 29. The paws of the rats were obtained for further analysis. Tissue Wnt5a, mitogen‐activated protein kinase (MAPK), Src tyrosine kinase and signal transducer, and activator of transcription‐3 (STAT3) mRNA expressions were determined by real‐time polymerase chain reaction. Resveratrol ameliorated the clinical and histopathological (perisynovial inflammation and cartilage‐bone destruction) findings of inflammatory arthritis. The tissue mRNA expressions of Wnt5a, MAPK3, Src kinase, and STAT3 were increased in the sham group compared to the control group. Resveratrol supplement decreased their expressions. The present study shows that Src kinase, STAT3, and Wnt signaling pathway are active in the CIA model. Resveratrol inhibits these signaling pathways and ameliorates inflammatory arthritis. © 2018 BioFactors, 45(1):69–74, 2019
Toward effectiveness and authenticity in PBL: A proposal based on a virtual learning environment in computing education
Authors: Bessa Bruno R. , Santos Simone , Duarte Breno J. 
Published: November 2018

AbstractProblem‐Based Learning (PBL) has gained widespread approval as a constructive, student‐centered approach to teaching, and learning. Advocating the use of real‐life problems to initiate and motivate the learning process, PBL is an inductive strategy promoting the understanding of new concepts as well as the development of professional skills, abilities, and attitudes. Thus, it is paramount that teachers and students implement PBL in conformity to its core principles. However, such implementation becomes a challenge, considering that PBL is fundamentally different from traditional instruction methods. Without the appropriate pedagogical and technological support, PBL's quality, effectiveness, and authenticity are at risk. In an attempt to overcome these challenges, this paper presents the PBL‐Coach Virtual Learning Environment (VLE), built upon PBL learning theories. This paper describes in detail a scientific investigation on a practical PBL implementation, driven by the quest to achieve the following goals: (i) Scaffold teachers and students in implementing the PBL method; (ii) Investigate useful and usable technological resources in the PBL process; (iii) Maintain PBL core principles for an authentic and effective learning process. As a result, three case studies are described and one is detailed to validate our investigation, consisting of a real‐world setting with clients, teachers, tutors, and students. Each case study provided a good level of evidence that PBL‐Coach, used in a real‐world, authentic setting, can promote an effective learning process through a number of carefully designed technological resources. Encouraging results motivated to evolve PBL‐Coach through Augmented and Virtual Reality components as future works.
Mechanistic Insight into the Catalytic Promiscuity of Amine Dehydrogenases: Asymmetric Synthesis of Secondary and Primary Amines
Authors: Tseliou Vasilis , Masman Marcelo F. , Böhmer Wesley , Knaus Tanja , Mutti Francesco G. 
Published: November 2018

AbstractBiocatalytic asymmetric amination of ketones, by using amine dehydrogenases (AmDHs) or transaminases, is an efficient method for the synthesis of α‐chiral primary amines. A major challenge is to extend amination to the synthesis of secondary and tertiary amines. Herein, for the first time, it is shown that AmDHs are capable of accepting other amine donors, thus giving access to enantioenriched secondary amines with conversions up to 43 %. Surprisingly, in several cases, the promiscuous formation of enantiopure primary amines, along with the expected secondary amines, was observed. By conducting practical laboratory experiments and computational experiments, it is proposed that the promiscuous formation of primary amines along with secondary amines is due to an unprecedented nicotinamide (NAD)‐dependent formal transamination catalysed by AmDHs. In nature, this type of mechanism is commonly performed by pyridoxal 5′‐phosphate aminotransferase and not by dehydrogenases. Finally, a catalytic pathway that rationalises the promiscuous NAD‐dependent formal transamination activity and explains the formation of the observed mixture of products is proposed. This work increases the understanding of the catalytic mechanism of NAD‐dependent aminating enzymes, such as AmDHs, and will aid further research into the rational engineering of oxidoreductases for the synthesis of α‐chiral secondary and tertiary amines.
Intravascular ultrasound analysis of intraplaque versus subintimal tracking in percutaneous intervention for coronary chronic total occlusions: One year outcomes
Authors: Finn Matthew T. , Doshi Darshan , Cleman Jacob , Song Lei , Maehara Akiko , Hatem Raja , Redfors Björn , Kalra Sanjog , Fried Justin A. , Liao Ming , Batres Candido , Moses Jeffery W. , Parikh Manish A. , Collins Michael B. , Nazif Tamim M. , Fall Khady N. , Green Phillip , Kirtane Ajay J. , Ali Ziad A. , Leon Martin B. , Mintz Gary S. , Karmpaliotis Dimitri 
Published: November 2018

AbstractObjectivesWe sought to determine the 1‐year outcomes of patients receiving successful chronic total occlusion (CTO) percutaneous coronary intervention (PCI) procedures comparing subintimal versus intraplaque wire tracking patterns.BackgroundCTO PCI utilizes both intraluminal and subintimal wire tracking to achieve successful percutaneous revascularization. Intravascular ultrasound (IVUS) can be used to precisely determine the path of wire tracking.MethodsFrom 2014 to 2016, data from patients undergoing CTO PCI were collected in a single‐center database. The primary composite endpoint was target vessel failure (TVF) defined as cardiovascular death, target vessel myocardial infarction (MI), or target vessel revascularization (TVR).ResultsIn total 157 patients with successful CTO PCI and concomitant IVUS imaging completed 1‐year follow‐up. Subintimal tracking was detected in 53.5% of cases and those patients had a higher incidence of prior PCI, prior coronary artery bypass grafting, and higher J‐CTO score. At 1‐year, the unadjusted rate of TVF in the subintimal tracking group was higher than the intraplaque group (17.9 vs. 6.9%, HR 2.74, 95% CI 1.00–7.54, P = 0.04), driven by numerically higher rates of TVR and peri‐procedural MI. After multivariable adjustment, no significant differences in the rates of the TVF between subintimal vs. intraplaque groups were present at 1‐year (TVF: HR 1.51, 95% CI 0.38–6.00, P = 0.55). Landmark analysis excluding in‐hospital events showed no significant differences in TVF to 1‐year.ConclusionsIVUS‐detected subintimal tracking was observed in over half of successful CTO PCI cases and correlated with baseline and angiographic factors that contributed to the overall rate of TVF at 1‐year.
Control of Spatially Homogeneous Distribution of Heteroatoms to Produce Red TiO2 Photocatalyst for Visible‐Light Photocatalytic Water Splitting
Authors: Hong Xingxing , Tan Jun , Zhu Huaze , Feng Ningdong , Yang Yongqiang , Irvine John T. S. , Wang Lianzhou , Liu Gang , Cheng Hui‐Ming 
Published: November 2018

AbstractThe strong band‐to‐band absorption of photocatalysts spanning the whole visible‐light region (400–700 nm) is critically important for solar‐driven photocatalysis. Although it has been actively and widely used as a photocatalyst for various reactions in the past four decades, TiO2 has a very poor ability to capture the whole spectrum of visible light. In this work, by controlling the spatially homogeneous distribution of boron and nitrogen heteroatoms in anatase TiO2 microspheres with a predominance of high‐energy {001} facets, a strong visible‐light absorption spectrum with a sharp edge beyond 680 nm has been achieved. The red TiO2 obtained with homogeneous doping of boron and nitrogen shows no increase in defects like Ti3+ that are commonly observed in doped TiO2. More importantly, it has the ability to induce photocatalytic water oxidation to produce oxygen under the irradiation of visible light beyond 550 nm and also the photocatalytic reduction of water to produce hydrogen under visible light. These results demonstrate the great promise of using red TiO2 for visible‐light photocatalytic water splitting and also reveal an attractive strategy for realizing the wide‐spectrum visible‐light absorption of wide‐band‐gap oxide photocatalysts.