bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potensi dan peluang Produk Halal Berbasis Rumput Laut
Authors: Diah Madusari Benny , Edi Wibowo Dwi 
Published: September 2019

75 persen wilayah Indonesia berupa laut dengan lebih dari 17 ribu pulau, serta panjang garis pantai mencapai 95.181 km. Potensi ini menunjukan sektor kelautan dan perikanan dengan segenap potensinya memiliki peluang menjadi tulang punggung pembangunan bangsa ini. Rumput laut salah satu potensi Perikanan kelautan Indonesia saat sekarang sudah mampu menjadi produk ekspor . Rumput laut tersebar di pantai Idonesia dan dapat berkembang biak dari erairan payau hingga perairan laut .Terdapat beragam jenis rumput laut yang telah dibudidayakan, namun terdapat beberapa jenis rumput laut unggulan yang telah dibudidayakan dan berpotensi di Indonesia. Berikut beberapa jenis rumput laut yang memiliki potensi dan merupakan produk potensi untuk ekspor yakni Gracilaria sp, Eucheuma cottoni, eucheuma spinosum, Gelidium, Acanthopora. Chondrococcus Hypnea, Ulva lactuta, Sargasum ,TurbinariaMelalui program Blue Economy telah menerapkan rumput laut sebagai produk yang mempunyai potensi pasca panen yang dapat dikonsumsi masyarakat sebagai makanan sehat dan halal. Berbagai produk pasca panen rumputlaut yang dikelola sesuai prosedur akan menghasilkan produk yang sehat dan halal. Diantara produk yang sudah dihasilkan dan memiliki pangsa pasar yang baik yakni agar agar, jelly, pewarna alami yang sangat dibutuhkan sebagai bahan dasar untuk pengolahan lebih lanjut sehingga menghasilkan produk makanan, obat obat dan kosmetika yang berkelanjutan, sehat dan halal.Kata kunci : Halal,sehat, rumput laut
Analisis Kualitatif Kandungan Boraks Pada Bahan Pangan Daging Olahan dan Identifikasi Sumber Boron dengan FTIR – ATR
Authors: Septiani Triayu , Roswien Anna P 
Published: September 2019

ABSTRAK Pangan terbagi menjadi pangan alami dan pangan olahan, pangan olahan umumnya menggunakan berbagai food additive agar memiliki shelf life yang panjang, rasa yang lezat dan penampilan yang menarik. Bahan tambahan pangan yang digunakan pada proses produksi pangan harus menggunakan bahan tambahan pangan yang disetujui oleh FDA dan Codex Alimentarius. Namun, pada prakteknya produsen juga seringkali menambahkan bahan tambahan pangan yang telah dilarang dan bersifat karsinogenik. Salah satu bahan yang dilarang penggunaannya dalam pengolahan pangan adalah boraks, namun bahan ini masih sering digunakan oleh produsen nakal karena harganya yang murah dalam memproduksi pangan olahan. Boraks atau natrium tetraborate yang umum digunakan sebagai pengawet merupakan senyawa dengan BM 381.37. Tujuan dari penelitian ini adalah untuk mengetahui keberadaan boraks dalam pangan daging olahan seperti bakso. Pada penelitian ini menggunakan bakso yang diperoleh dari pasar tradisional dan pedagang kaki lima di sekitar Universitas YARSI. Hasil dari penelitian ini adalah sepuluh sampel dengan berat pada kisaran 39.3470 – 55.6263 telah diuji kualitatif dengan pengulangan sebanyak dua kali menggunakan turmeric paper menunjukkan mengalami perubahan warna yang mengindikasikan sampel positif mengandung boraks. Pengujian kualitatif juga dilanjutkan dengan menggunakan FTIR spectrometry untuk mengidentifikasi finger print pada boric acid, natrium tetraborate, dan disodium tetraborate. Perbedan finger print pada transmitant boric acid, natrium tetraborate, dan disodium tetraborate diamati pada region wavenumber 1800 – 600 cm-1.Key Words : Boraks, Boric Acid, Sodium Tetraborate, Disodium Tetraborate
Analisis Lemak Sapi dan Lemak Babi Menggunakan Gas Chromatography (GC) dan Fourier Transform Infra Red Spectroscophy Second Derivative (FTIR-2D) untuk Autentifikasi Halal
Authors: Yunita Prabawati Susy , Fajriati Imelda 
Published: September 2019

ABSTRAKTelah dilakukan penelitian analisis lemak sapi dan lemak babi menggunakan Gas Chromatography (GC) dan FTIR second derivative (2D). Penelitian dilakukan untuk mempelajari perbedaan karakteristik dan profil kedua lemak dalam proses autentifikasi halal. Sampel lemak dipisahkan menggunakan ekstraksi Soxhlet dengan pelarut n-heksana selama 2 jam. Hasil ekstraksi selanjutnya dianalisis menggunakan GC dan FTIR 2D. Hasil penelitian menunjukkan bahwa, dengan GC didapatkan kandungan asam lemak jenuh (asam palmitat dan asam okta-dekanoat) pada lemak sapi lebih banyak daripada asam lemak jenuh pada lemak babi. Adapun kandungan asam lemak tak jenuh (asam oleat, linoleat dan asam linolenat) pada lemak babi lebih tinggi daripada lemak sapi. Hasil ini dibuktikan dengan profil spektra FTIR 2D, dimana munculnya serapan pada bilangan gelombang 3000-3010 cm-1 yang merupakan vibrasi ulur dari ikatan rangkap –C=CH cis pada profil spektra lemak babi, dan tidak nampak serapan pada bilangan gelombang tersebut pada profil lemak sapi. Dengan demikian, analisis lemak sapi dan lemak babi menggunakan GC dan FTIR 2D dapat digunakan untuk autentifikasi halal. Kata Kunci: Ekstraksi Soxhlet, GC, FTIR second derivative(2D), autentifikasi halal.
4-Channel Tunable Optical Demultiplexer Based on Nonlinearity Phenomenon in 2D Resonant Cavity Photonic Crystals
Authors: Talebzadeh Reza , Mehdizadeh Farhad , Naseri Ali 
Published: September 2019

AbstractIn this paper, we propose a new structure based on photonic crystals to realise a demultiplexing operation for dense wavelength division multiplexing transmission systems. In this demultiplexer, the resonant cavities were responsible for selecting the wavelength. By imposing defect rods to these cavities, the modes could resonate at the desired frequencies. As we wanted to see the nonlinear effects, the material that was chosen for defect rods were doped glass. The refractive index of this glass in 1550 nm is 1.41. Increasing the input power causes variation in the refractive index of defect rods and as a result resonant condition of whole cavity alerts so a tenable demultiplexer can be investigated. Based on the results, the average pass bands of channels are near to 1.5 nm and the channel spacing is approximately 3.95 nm. The proposed demultiplexer acts in a near-complete transmission efficiency and the mean value of the crosstalk was −19 dB.
Pasireotide-LAR in acromegaly patients treated with a combination therapy: a real-life study
Authors: Lasolle Hélène , Ferriere Amandine , Vasiljevic Alexandre , Eimer Sandrine , Nunes Marie-Laure , Tabarin Antoine 
Published: September 2019

Purpose
Little data are available regarding the safety and efficacy of switching to Pasireotide-LAR monotherapy in acromegaly patients with partial resistance to first-generation somatostatin agonists (1gSRL) who require combination treatment with cabergoline or pegvisomant.

Method
In this monocentric prospective study within a tertiary university hospital, 15 consecutive acromegalic adults partially resistant to 1gSRL treated with octreotide LAR or lanreotide SR, and cabergoline (n = 4, 3.5 mg/week) or pegvisomant (n = 11, median dose 100 mg/week), were switched to Pasireotide-LAR (8 with 40 mg/month; 7 with 60 mg/month). Immunohistochemical expression level of SSTR5 and the granulation pattern of nine somatotroph adenomas were retrospectively determined to test for a correlation with the therapeutic efficacy of Pasireotide-LAR.

Results
Median IGF-1 concentration at the first evaluation (median 3 months) was similar to baseline (1.0 vs 1.1 ULN). 11/15 patients had IGF-1 levels ≤1.3 ULN before and after the switch but individual changes were variable. Hyperglycemia was frequent and greater in diabetic patients. 7/15 patients stopped Pasireotide-LAR due to lack of control of IGF-1 or intolerance. 8/15 patients received Pasireotide-LAR for a median of 29 months with IGF-1 levels ≤1.3 ULN and acceptable glucose tolerance (median HbA1c 6.1%). Two patients required initiation of oral antidiabetic treatment. The intensity of SSTR5 expression and the granulation pattern of adenomas were of limited value for the prediction of Pasireotide-LAR effectiveness.

Conclusion
Pasireotide-LAR may represent a suitable therapeutic alternative in a subset of acromegalic patients requiring combination therapy involving a 1gSRL
Vitamin B12 deficiency and diabetic neuropathy in patients taking metformin: a cross-sectional study
Authors: Alvarez Mauricio , Sierra Oswaldo Rincón , Saavedra Ginna , Moreno Sergio 
Published: September 2019

Objective
Vitamin B12 deficiency resulting from metformin use has been demonstrated in multiple studies. In this study, we aimed to evaluate the prevalence of vitamin B12 deficiency in patients with chronic metformin use and the relationship between vitamin B12 deficiency and diabetic neuropathy.

Methods
A cross-sectional study was conducted with 162 patients. Vitamin B12 levels were measured by chemiluminescence immunoassay. Diabetic neuropathy was evaluated by patient record, nerve conduction and Michigan test for the diagnosis of diabetic neuropathy. Additional data, including demographic characteristics were collected. A linear regression model was used to evaluate variables that correlated with vitamin B12 levels and diabetic neuropathy.

Results
Low vitamin B12 levels were found in 7.3% (95% CI: 4.0–12%) of patients. In those with diabetic neuropathy, altered (low and borderline) vitamin B12 level was 64% (95% CI: 47–78%) compared to 17% (95% CI: 10–26%) in patients without diabetic neuropathy (coefficient: −110.8; CI 95%: −165.8, −59.7). Those taking a higher metformin dose had lower levels of vitamin B12 (coefficient: −0.061; CI 95%: −0.09, −0.024). In addition, female patients had higher levels of vitamin B12 compared to men (coefficient: 49.1; CI 95%: 2.3–95).

Conclusions
Vitamin B12 deficiency is highly prevalent, especially in patients with diabetic neuropathy. In this study an inverse correlation was found between diabetic neuropathy and the plasma level of vitamin B12. Higher doses of metformin and male sex were factors related to lower levels of vitamin B12.
Multidrug-Resistant Bacteria and Disease Progression in Patients with End-Stage Liver Disease and after Liver Transplantation
Authors: Friedrich Kilian , Krempl Jessica , Schamoni Shigehiko , Hippchen Theresa , Pfeiffenberger Jan , Rupp Christian , Gotthardt Daniel Nils , Houben Philip , Von Haken Rebecca , Heininger Alexandra , Brenner Thorsten , Mehrabi Arianeb , Weiss Karl-Heinz , Mieth Markus 
Published: September 2019

Background: Multidrug-resistant (MDR) pathogens represent an emerging challenge in end-stage liver disease and in liver transplant recipients.
Methods: We evaluated the impact of MDR bacteria upon clinical outcomes in patients with end-stage liver disease (n = 777) at the time of enrollment on the liver transplant (LTx) waiting list, after first LTx (n = 645), and after second LTx (n = 128).
Results: Colonization/infection with MDR bacteria was present in 72/777 patients on the waiting list, in 98/645 patients at first LTx, and in 46/128 patients at second LTx. While on the LTx waiting list, the time until first hydropic decompensation (p = 0.021), hepatic encephalopathy (p < 0.001) and hepatorenal syndrome (p < 0.001) was reduced in the presence of MDR bacteria, which remained an independent risk factor of poor survival in multivariate analysis (p < 0.001). Following first and second liver transplant, MDR bacteria were associated with an increased risk of infection-related deaths (first LTx: p < 0.001; second LTx: p = 0.037) and reduced actuarial survival (first LTx: p < 0.001; second LTx: p = 0.046).
Conclusions: We showed that MDR pathogens are associated with poor outcomes before, after first and after recurrent LTx.
Step layered combination of noninvasive fibrosis models improves diagnostic accuracy of advanced fibrosis in nonalcoholic fatty liver disease
Authors: Yang Mei , Jiang Lina , Wang Yijin , Li Xi , Zou Zhengsheng , Han Tao , Nan Yuemin , Lu Fengmin , Zhao Jingmin 
Published: September 2019

Background and Aims: Liver fibrosis is stage-dependently associated with non-alcoholic fatty liver disease (NAFLD) progression. The increased awareness of non-invasive diagnosis has led to the establishment of many fibrosis diagnosis models with various accuracies. We aimed to evaluate the diagnostic performance of nine clinical non-invasive fibrosis models in NAFLD and provide an optimal diagnostic method for advanced fibrosis by step layered combination of non-invasive models.
Methods: 453 consecutive patients with biopsy-proven NAFLD were enrolled from three centers and were divided into study cohort and validation cohort randomly. Aspartate aminotransferase-to-platelet ratio index (APRI), BARD, FiB-4, FibroMeter NAFLD, Forns’ Index, Hui model, non-invasive Koeln-Essen- index (NIKEI), S Index and NAFLD fibrosis score (NFS) were calculated. The high area under the receiver operating characteristic curve (AUROC) models were stepwise combined for further diagnosing NAFLD advanced fibrosis.
Results: All models had good performance with high negative predictive value (NPV) and specificity for diagnosing fibrosis, while positive predictive value (PPV) and sensitivity were low. APRI, BARD, FibroMeter NAFLD and NIKEI had higher AUROCs and their step layered combination for diagnosing advanced fibrosis showed high specificity, sensitivity, NPV and PPV up to 89.13%, 72.50%, 74.36%, and 88.17%, which also performed well in the validation cohort.
Conclusions: APRI, BARD, FibroMeter NAFLD and NIKEI had better diagnostic accuracy, and could be preferred for diagnosing NAFLD fibrosis. The step layered combination of these models performed much better than each single scoring system for diagnosing advanced fibrosis, provides valuable reference for clinical practice and might be a potential substitution of liver biopsy.
Structure and properties of layer, surfaced on HARDOX 450 steel by boron containing wire
Authors: Ivanov Yu. F. , Gromov V. E. , Romanov D. A. , Klopotov A. A. , Rubannikova Yu. A. 
Published: September 2019

Analysis of structure phase states and properties of the layers formed on HARDOX 450 low alloy steel by welded-on wires with boron content of 4.5 and 6.5 % wt. was made by the methods of modern physical material science. In the initial state HARDOX 450 steel has the structure of tempered martensite, in the volume and along the boundaries of crystals of it the cementite particles are located. The particles located in the volume have acicular shape and those along boundaries are mainly round. The presence of extinction bend contours has been revealed, indicative of the curvature torsion of crystal lattice of the material’s portion. They originate and finish on the interfaces of martensite crystals. Scalar density of chaotically located dislocations and forming the netlike substructure is 6.2·1010 cm–2. The layer welded on HARDOX 450 steel has microhardness increasing by more than two-fold that of the base. Analysis of state diagrams of Fe – C, Fe – B, B – C systems and polythermal cross–sections in Fe – C – B system has shown that the rapid cooling of Fe23C6 – Fe23B6 alloys from liquid state would facilitate the formation of multiphase structural states. It is stated by the methods of transmission electron diffraction microscopy that the reasons for the high microhardness level of the surface layers are the following: formation of iron borides and crystals of ultafine-dispersion (up to 100 nm) packet martensite with high level (~1011 cm–2 ) of scalar density of dislocations; presence of nanodimentional particles of iron and boron carbides in the volume and on the boundaries of martensite crystals; high level of curvature torsion of crystal lattice of iron borides and α-phase grains, caused by the internal stress fields along interphase (interface of iron boride crystals and α-phase grains) and intraphase boundaries (interface of iron borides and martensite crystals packet). Increase in boron concentration from 4.5 to 6.5 % is accompanied by the sufficient increase (by 1.2 – 1.5 times) in hardness of welded layer. It is caused by the increase of dimensions and relative content of iron boride regions by 1.5 – 2.0 times.
Calculation of changes in specific volumes of Fe – C system alloys depending on carbon content and temperatures
Authors: Gabelaya D. I. , Kabakov Z. K. , Mashchenko M. A. 
Published: September 2019

The work presents a new technique for determining the temperature dependence of the alloy specific volumes in Fe – C equilibrium system based on known from the literature calculated and empirical dependence for account of the phases’ specific volumes. These data were based on the independent reports of S.F. Yuryev and were obtained for temperatures below 1200 °C. When using these forms at temperatures above 1200 °C, the specific volume of austenite exceeds specific volume of ferrite. However, it is known that austenite has the smallest specific volume among all phases of the Fe – C system. In this regard, in the field of high temperatures, it is proposed to use other dependences that do not contradict the physics of polymorphic and phase transformations in this system. Thus the authors have obtained the general expressions for calculating the alloys’ specific volumes separately for three intervals of carbon concentrations in which the change in shares of the temperature phases are calculated according to Fe – C equilibrium diagram using the lever relation. As an example, results of the calculated determination of specific volumes of alloys with carbon vontent of 0.05, 0.13 and 0.33 % in the temperature range of 20 – 1600 °C are considered. The presented results are compared with the results obtained with the help of the phase diagram calculation package JMatPro®, on the basis of which the adequacy of the proposed calculation method was established. The developed technique can be used to calculate not only specific volumes of alloys, but also their density and coefficient of linear expansion depending on temperature and carbon concentration. It is the basis for the correct use of methods for determining the size of continuous cast billets due to shrinkage in order to correctly configure the equipment of continuous casting machines.
Modeling of overloads of raising mechanism in metallurgical overhead cranes
Authors: Varlamov V. V. , Kipervasser M. V. , Gerasimuk A. V. 
Published: September 2019

Electromechanical processes occurring when the load is lifted by an overhead crane are considered. The main idea of the work is to identify emergency mode (crane overload) by a method based on control of stator current of lift motor. To obtain stator current diagrams of electric motor, mathematical model of overhead crane (three-mass circuit) has been developed, which includes equations describing elastic properties of crane beams and its rope. A system of (α, β) coordinates, fixed relative to electric motor stator, is adopted to describe the drive asynchronous motor. Lifting cycle is considered as sequence of three steps: choice of the rope “slack”; rope tension; separation of cargo lifting. For each stage, a system of differential equations has been compiled describing motion of masses of overhead crane elements and electrical parameters of electric motor. Initial and boundary conditions for each of the stages were determined. Preliminary transformations of the system of equations to their solution by numerical methods and subsequent modeling of stages of lifting loads were carried out for different weights. Sequential solution of three boundary value problems allows obtaining values of stator currents at time of load separation. Diagrams of stator phase currents of an electric motor were obtained for loads of different mass. Simulation results indicate the presence of fixable difference in magnitudes of stator currents after the load is separated from the support surface. On basis of the developed model and the study results, a functional diagram of crane overload protection device is proposed and its principle of operation is described. It consists in controlling lifted load mass and stator current when liftingthe load. Conclusion is made about feasibility and effectiveness of monitoring electrical values of lifting motor for development of overhead crane protection against overloads. Effectiveness of the proposed system was evaluated.
Las tretas del débil: la autotraducción como subversión lingüística patriarcal en la literatura de la escritora puertorriqueña Rosario Ferré
Authors: Sambolín-Santiago Aurora 
Published: September 2019

La subversión lingüística ha sido una herramienta rupturista para muchas escritoras y escritores en toda Latinoamérica en diferentes momentos de su historia, frente al canon literario y la homogenización de las diferentes identidades nacionales. En este contexto se analiza la literatura de Rosario Ferré, quien forma parte de la Generación del 70 puertorriqueña, que impulsó conceptualizaciones sobre identidades puertorriqueñas híbridas. Estas conceptualizaciones transgredieron la identidad nacional hispanófila que algunas instituciones y organizaciones políticas isleñas habían oficializado en contraposición a los intentos colonialistas de los Estados Unidos por asimilar lingüística y culturalmente a los puertorriqueños. Dentro de este contexto, el caso de la escritora Rosario Ferré es muy especial debido a su posición político-social, su particular incursión en el mercado literario estadounidense, al publicar en un inglés “contaminado” lingüística y culturalmente por el español, y su práctica subversiva de autotraducción sobre la que elegantemente se da el lujo de teorizar en una de las tramas de su novela The House on the Lagoon (1995), que se examina en este artículo.Fecha de recepción: 30/04/2019Fecha de aceptación: 12/07/2019¿Cómo citar este artículo? Sambolín-Santiago, A. (2019). Las tretas del débil: la autotraducción como subversión lingüística patriarcal en la literatura de la escritora puertorriqueña Rosario Ferré. Mutatis Mutandis. Revista Latinoamericana de Traducción, 12(2), 475-499. doi: 10.27533/udea.mut.v12n1a07
Health related quality of life in children with cancer and chronic diseases
Authors: Yağcı-Küpeli Begül , Akın Kudret Helin , USLUOĞLU Feyruz , KÜPELİ Serhan 
Published: September 2019

Purpose: Health related quality of life (HRQOL) concept is one of the major outcome measures in management of chronic diseases in children. Herein we aimed to review HRQOL by using PedsQL Generic Core Scales in children with cancer and chronic diseases. Materials and Methods: All patients with cancer under treatment (oncology group), attention deficit hyperactivity disorder (ADHD), nephrological disorders like recurrent urinary tract infections and other endocrinologic disorders such as precocious puberty and growth retardation and their parents who gave consent were included in the study. Turkish version of PedsQL 4.0 Generic Core Scales self and parent proxy-reports were used for all patients of 8-12 and 13-18 years of age.Results: There were 48 children in oncology group; 44 in non-oncology group. The most common diagnoses were leukemia, non-Hodgkin lymphoma and brain tumors in the oncology group. Children reported significantly higher scores in the school subscale and physical functioning subscale, psychosocial functioning, and total scale scores in the non-oncology group compared to patients with cancer. A strong positive significant correlation was detected between all subscales except for social functioning scores of children and parents in child self-report and parent proxy-report correlations. Conclusion: Cancer is a devastating disease that impair functioning more than other chronic diseases in all areas of life of children and parents. PedsQL Genereric Core Scales is a usefull tool for evaluating HRQOL in both cancer and other chronic diseases.