bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tocotrienol-Rich Fraction Modulates Genes Expression in Oxidative Stress-induced Caenorhabditis e legans
Authors: Aan Goon Jo , Karim Noralisa Abdul , Zainudin Mohd Shahril Aszrin , Makpol Suzana 
Published: September 2019

Objective: The study was done to determine the effect of Tocotrienol rich fraction (TRF) on the expression of RNAs in C. elegans under oxidative stress.
Methods: The nematodes were divided into 4 groups and treated accordingly: control; TRF; hydrogen peroxide (H202); TRF treatment before and after H202-induction (TRF+H202+TRF). Expressions of RNAs were analyzed with Affymetrix Genechip C. elegans Genome Array and Genespring GX11 software where differentially expressed genes were further analyzed using gene ontology (GO). Selected genes (unc-15, cit-1.2, ftn-1, rsks-1, unc-4 and daf-12) were analyzed with RT-qPCR to validate the results.
Results: TRF modulated the expression of 314 genes involved in determination of adult lifespan, regulation of growth and lipid modification. A total of 440 genes involved in RNA metabolic processes, transcription, growth and differentiation of muscle and nerve cells were differently expressed following H202 induction. TRF treatment before and after H202- induction resulted in 438 differentially expressed genes involved in RNA metabolic processes, transcription, response to xenobiotic stimulus and protein amino acid phosphorylation.
Conclusion: TRF modulates the expression of genes involved in the regulation of lifespan in C. elegans.
Bangladesh Journal of Medical Science Vol.18(4) 2019 p.711-721
Assessment the relation between lifestyle with mental health and educational achievement in nursing students
Authors: Heidari Mohammad , Borujeni Marzieh Borjian , Borujeni Mansureh Ghodusi , Borujeni Mansureh Ghodusi , Rezaei Parvin 
Published: September 2019

Objective: This study was aimed to assess the correlation between lifestyle with mental health and educational achievement ofnursing students.
Materials and Methods: This is a descriptivecorrelational study that all students in nursing college in 2015 were selected by the census sampling method. Data gathering tool were standard Walker’s lifestyle questionnaire and General Health Questionnaire-28 and data were analyzed by SPSS/21.
Results: The results reported that most subjects (61.01%) displayed moderate levels of lifestyle. In considering domains mental health37.28%, were depression and 34.74% anxiety. Based on the Pearson correlation coefficient test, there was a diverse correlation between lifestyle (p=0.004, r=-0.34) and educational achievement (p=0.001, r=-0.24) with mental health but there was a direct linear correlation between lifestyle and educational achievement.
Conclusion: Regarding the role of lifestyle and mental health and to ensure the efficiency and dynamism of the people in the education and prevention of academic failure recommended that be scheduled byimprove methods of lifestyle to promote educational status and activate counseling centers andguidance on psychological issues the mental health.
Bangladesh Journal of Medical Science Vol.18(4) 2019 p.722-728
Association of interleukin-6 polymorphism (-634C/G) in the promoter region with diabetic nephropathy in type 2 diabetes mellitus
Authors: Talib Rakshanda , Kashif Muhammad , Tahir Romeeza , Ahmed Nadeem , Khaliq Saba , Mubarik Bushra , Abbas Afia , Jahan Shah , Afzal Nadeem 
Published: September 2019

Background:Long term microvascular complications of DM includes: nephropathy, retinopathy, and neuropathy. Increased level of IL-6 and its polymorphism have been associated with diabetic nephropathy.The present study was designed to determine serum level of IL-6 and C/G polymorphism at − 634 position in the promoter region of IL-6 gene in patients with type 2 diabetes mellitus (T2DM) with and without nephropathy.
Method: This comparative study was comprised of 164 subjects, divided into two groups of 82 subjects in each. The subjects who had diabetes for more than 5 years without nephropathy were labeled as group-I and the subjects who had diabetes for more than 5 years with nephropathy were labeled as group-II. IL-6 polymorphism was detected by RFLP and its level was determined by ELISA technique. Data was analyzed using SPSS 20.0.
Results: In group-I, 14 (17.1%) patients had CC, 47 (57.3%) had CG and 21 (25.6%) had GG polymorphism. In group-II, 9 (11%) patients had CC, 69 (84.1%) had CG and 4 (4.9%) had GG polymorphism. Pearson’s correlation test determined significant association of IL-6 polymorphism (CC,CG,GG) in both the groups (p <0.001). In patients of CC polymorphism, median levels of IL-6 was high in group-I (4.2) as compared to group-II (3.2),whereas in patients of CG polymorphism, median levels of IL-6 was high in group-II (3.8) as compared to group I (3.7) while in GG polymorphism, median levels of IL-6 was same in both the groups. On comparison of IL-6 polymorphism and level of IL-6 there was no statistically significant difference between the two groups (p1=0.304, p2=0.425 respectively).
Conclusions: Statistically significant difference in the frequencies of allele (CC,CG,GG) between two groups is pointing towards the protective role of GG allele as it was predominant in T2DM patients without nephropathy.
Bangladesh Journal of Medical Science Vol.18(4) 2019 p.741-747
Facilities available in the medicine shops in Chittagong city corporation area: A cross- sectional study conducted in Bangladesh
Authors: Jakaria Md , Sayeed Mohammed Aktar 
Published: September 2019

Background: The aim of this was to inspect the facilities available in the medicine shops and their impacts on quality medicines and health services to be found in the Chittagong City Corporation of Bangladesh.
Method: This cross-sectional study was conducted from December 2015 to February 2016. A well-designed standard protocol developed by the project supervisor. Different information was collected from the medicine shops.
Results: Among the total 190 studied medicine shops, pharmacist and physician were available in 99 (52%) and 51 (27%) shops, respectively. A-grade pharmacist was available in four(04) shops. However, no air conditioner was found in 14 shops, while a refrigerator was not found in 15 shops but these shops were facing sun rays from the east side. In addition, four (04) and five (05) shops were not used the air conditioner and refrigerator, respectively but they were facing sun rays from the west side.
Conclusion: Facilities in the medicine shops in this city were good, however, we think the responsible person should be more aware to ensure proper retail pharmacy practices.
Bangladesh Journal of Medical Science Vol.18(4) 2019 p.760-763
Lysosomes of Cancerous and Normal cells in Response to Low-energy/low-dose Medical Diagnostic X-rays
Authors: Tungjai Montree , Tubthaing Nuttakan , Kothan Suchart 
Published: September 2019

Background: Low-energy/low-dose ionizing radiation is increasingly being used in medical diagnosis, yet the effects of low-energy/low-dose medical diagnostic X-rays on biological systems remains a mystery. Thus, the aim of this present study is to determine the characteristics of lysosomes of cancerous and normal cells in response to low-energy/low-dose medical diagnostic X-rays.
Methods and materials: Three cell lines composed of peripheral blood mononuclear cells (PBMCs), adriamycin-sensitive erythroleukemia cells (K562), and adriamycin-resistant erythroleukemia cells (K562/adr), were all exposed to low-energy/low-dose medical diagnostic X-rays that operated at 50, 70, and 100 kV, and 100 mAs for obtaining radiation doses at 0.03, 0.07, and 0.10 mGy, respectively. Accumulation of acridine orange in the lysosomes of each cell line was determined using flow cytometry completed at 4 and 6 hours-post irradiation.
Results: The data showed an increase in fluorescence intensity of acridine orange in three irradiated cells line at 4 hours post-irradiation, but this intensity did not change at 6 hours post-irradiation when compared to that of corresponding non-irradiated cells.
Conclusion: This finding suggests that changes in lysosomes might be a response to low-energy/low-dose medical diagnostic X-rays.
Bangladesh Journal of Medical Science Vol.18(4) 2019 p.830-834
Reincarnation of Memory, or Portrait of Generation in the Interior of Time: “Children of the Milky Way” by Dokiia Humenna
Authors: Vasylenko Vadym 
Published: September 2019

The paper analyzes the tetralogy of novels by Dokiia Humenna “Children of the Milky Way” in the context of the postwar Ukrainian diaspora ﬁction. The researcher raises such issues as the genre nature, narrator’s position, problem of the relationship between the categories of time and space, and the alternative autobiography of the novel. The process of writing the novel is considered as an attempt to normalize the writer’s own traumatic experience, caused by two decades of totalitarian terror and repressions. Dokiia Humenna’s novel is regarded in the context of such genres as family chronicle and ‘novel of generations’, which was updated in Ukrainian literature of the post-war period as an attempt to overcome the threatening tendencies of the entropy. At the same time, considering the fact that the novel was written on the verge of ﬁction and documentaries, the researcher suggested reviewing the work in the context of testimonial literature. It is emphasized that ideas of generational consciousness and generational dimension of time shape the novel, and the concept of generation is associated with categories of ancestry, memory, trauma, and identity. The generation of Ukrainian 1920s, which Dokiia Humenna considers as her own, emerges in the novel as a complex and heterogeneous socio-cultural phenomenon, represented by historical ﬁ gures that became symbols and signs of their time (Mykola Khvylovyi, Mykola Zerov, and others), by literary stories of their alter ego, and ﬁctional characters, sometimes based on several real prototypes.
The myth of primordialism is one of the most important in the novel. It is represented by the archetype of a hamlet, a patriarchal micromodel of Ukraine, traditional in classical Ukrainian literature. In addition, the author of the paper raised a question about the presence of the writer’s alternative autobiographies in the novel, which might be the ways of constructing her own identity.
Конституціоналізація соціально- економічних прав: український ракурс постановки проблеми
Authors: Загоруй І. С. 
Published: September 2019

Конкретизація проблеми забезпечення соціально-економічних прав громадян України в теоретико-правовому аспекті набула вигляду необхідності їх конституціоналізації. Надзвичайна трудність процесів державотворення на сучасному етапі потребує не тільки постановки цієї проблеми, але й якомога швидкого її вирішення. У статті розглянуто: а) поняття та б) процес конституціоналізації в сучасних їх інтерпретаціях як вітчизняними вченими, так і зарубіжними. Теоретичні положення ілюстровано історичними прикладами, зокрема з історії України. Показано, що процес конституціоналізації соціально-економічних й інших прав людини і громадянина розпочатий Конституцією України 1996 року; подано його основні характеристики: порівняння з іншими правами, поява нових прав, яких раніше ніколи не було, орієнтування на міжнародні правові акти. У висновках йдеться про відповідність поняття конституціоналізації в зазначеній сфері вітчизняної практики та процесу конституціоналізації міжнародним вимогам.
A Retórica e o Sistema: uma nova leitura da sociologia do Direito
Authors: Magalhães Raul Francisco 
Published: September 2019

O livro As relações entre direito política e sociedade – Retórica e Teoria da Ação na análise da argumentação em casos difíceis no Supremo Tribunal Federal, de Wagner S. Rezende, origina-se em sua tese de doutorado, defendida no PPG em Ciências Sociais da UFJF. Ele faz uma crítica original da teoria dos sistemas de Niklas Luhmann, a partir de uma teoria da ação aplicada ao direito na qual os atores manipulam retóricas como seu principal instrumento para a geração de sentenças sobre casos complexos. Um profundo estudo de alguns dos chamados hard cases, com os quais o STF se enfrentou, desvela como juízes são levados a usar argumentos fundados em noções exógenas ao sistema do direito e que são incorporadas para a realização de um fim prático, ou seja, a produção das sentenças. O livro se afirma como uma nova e original leitura da sociologia do direito e tem promissoras perspectivas como programa de pesquisa.
Методичні основи оцінки технічного рівня виробничо-технічної бази військових ремонтних органів
Authors: Шишанов М. О. , Гуляєв А. В. , Каніщев В. В. 
Published: September 2019

Наведено результати аналізу факторів, що впливають на оцінку технічного рівня виробничотехнічної бази військових ремонтних органів та показники ефективності ремонту озброєння йвійськової техніки.
Методика прогнозування стану парку зенітних ракетних комплексів Повітряних Сил Збройних Сил України для вирішення задач планування розвитку озброєння та військової техніки
Authors: Ланецький Б. М. , Коваль І. В. , Селезньов С. В. 
Published: September 2019

Розглядається методика прогнозування стану парку зенітних ракетних комплексів (ЗРК) у середньостроковій та довгостроковій перспективах у складі Повітряних Сил ЗбройнихСил України. В основі цієї методики покладена модель залежності кількості боєготових ЗРК від календарної тривалості експлуатації, що враховує початковий розподіл ЗРК за роками ви-готовлення, обрану стратегію експлуатації і ремонту ЗРК та інші фактори.
Використання математичного апарату рефлексивних ігор для прийняття управлінських рішень при розробці й обґрунтуванні раціональної стратегії управління процесами виробництва, модернізації, ремонту зразків озброєння та військової техніки
Authors: Шишанов М. О. , Шуригін О. В. , Деркач І. І. , Шевцов М. М. 
Published: September 2019

Розглядаються задачі розвитку та удосконалення процесів інформаційного управління з використанням рефлексивних ігор при виробництві, модернізації, ремонті зразків озброєння та військової техніки, формування потоків інформації, обміну нею для прийняття рішення щодо етапів (циклів) робіт при проведенні відкритих процедур (торгів) закупівлі робіт і послуг.
Числове моделювання пробиття гомогенної перешкоди ударниками з різною формою головної частини
Authors: Бісик С. П. , Чернозубенко О. В. , Схабицький В. Р. , Сливінський О. А. , Ханюков В. А. 
Published: September 2019

Надані результати числового моделювання пробиття ударниками з різною формою головної частини гомогенної перешкоди. Визначено стійкість, збіжність та похибку рішення з використанням числової моделі порівняно з відомими експериментальними даними.
Ключові реформи сектору безпеки і оборони та результати їхнього впровадження
Authors: Павловський І. В. 
Published: September 2019

Проведено аналіз загроз у сфері національної безпеки, основних завдань підвищення рівня обороноздатності держави та реформування оборонної сфери. Визначено вирішальні для забезпечення національної безпеки України аспекти управлінської діяльності, що потребують подальшої імплементації.
Seyyah Notlarına Göre Safevilerde Düğün, Ölüm, Yas ve Bayram Merasimleri
Authors: ERDOĞAN Eralp 
Published: September 2019

Safevi Devletin’de
Şii inanışına uygun olarak yıl boyunca bazı dini merasimler yapılmaktaydı. 12
ayın sadece 5 ayı merasimsiz geçmekteydi. Seyyahların en çok bahsettiği dini
merasimler Hz. Hüseyin anısına yapılan Muharrem ayı matemi ve Kurban
merasimleriydi. Şeriat hükümlerine göre yapılan diğer merasimler ise düğün ve
cenaze merasimleriydi. Safevilerde dini olmayan en önemli merasim ise yeni yıl
dolayısıyla gerçekleşmekteydi. Özellikle devlet tarafından organize edilen
merasimlere birçok insan katılır ve bu merasimler çok görkemli geçerdi. Bu çalışma çeşitli zamanlarda Safevi Devleti’ne
gelen 12 seyyahın gözlemlerini içermektedir. Çalışmanın asıl amacı seyyahların
şahit olduğu dini ve milli merasimlerin Şii Türk Devleti olan Safevilerde nasıl
gerçekleştiğinin ortaya çıkarılmasıdır. Seyahatnameler incelendikten sonra
merasimlere yönelik notlar çıkarılmış ve tasnif edilerek yazılmıştır. Buna göre
merasimlerin çoğu özellikle başkent İsfahan’da coşkulu bir biçimde
gerçekleşmekteydi. Halkın büyük katılım gösterdiği bu törenler Safevi toplum
hayatında önemli bir yer tutmaktaydı.
PERCEPCIÓN SOBRE EL CONSUMO DE SUSTANCIAS PSICOACTIVAS POR ESTUDIANTES DE MEDICINA DE LA PROVINCIA DE ICA, PERÚ 2010
Authors: Adán Antonio Pineda-Rodríguez  
Published: September 2019

Con el objetivo de determinar la percepción sobre el consumo de sustancias psicoactivas en estudiantes de la provincia de Ica se realizo un estudio de tipo descriptivo transversal, para el cual se aplicó una encuesta estructurada a una muestra no probabilística estratificada, para todos los años de estudios, en la Facultad de Medicina de la Universidad San Luis Gonzaga de Ica. Para el análisis de los datos se usó estadística descriptiva en el software Excel 2007. El número de encuestados fue de 195, con una edad promedio de 22 ±3 años. La percepción: peligro o muy peligroso, sobre el consumo de sustancias psicoactivas, fue del 78,5% para fumar cigarrillos, 83,6% para el consumo de bebidas alcohólicas frecuentemente; un 80% considera nada peligroso o poco peligroso al consumo de café. Concluimos que existe una alta percepción de peligro sobre el consumo de sustancias psicoactivas; sin embargo, un gran porcentaje de estos estudiantes, ha consumido alguna vez un tipo de ellas. ( Rev. méd. panacea 2011; 1: 44-46 ).
CONDICIONES LABORALES Y NIVEL DE ESTRÉS EN ENFERMEROS DE UN HOSPITAL PÚBLICO PERUANO
Authors: Wilson Sauñe-Oscco  , Carmen E. Bendezù-Sarcines  , Olinda Oscco-Torres  
Published: September 2019

Objetivo: Determinar las condiciones laborales y nivel de estrés en los Enfermeros de un hospital público peruano en el año 2011. Material y métodos: Se realizó un estudio de tipo descriptivo, de corte transversal, la muestra está constituida por 44 enfermeros que se dedican a la labor asistencial, los cuales fueron seleccionados a través del muestreo no probabilístico y por conveniencia de acuerdo a los criterios de inclusión y exclusión. Resultados: Referente a las condiciones laborales son consideradas desfavorables en un 70% y favorables en un 30%. Respecto al nivel de estrés, el 52% presenta nivel de estrés medio, el 34% nivel de estrés bajo y un 14% presenta estrés alto. Conclusiones: Las condiciones laborales son desfavorables y el nivel de estrés es moderado en los enfermeros de un Hospital público peruano.
Actualización sobre las Enfermedades Pulmonares Intersticiales Difusas (E. P. I. D)
Authors: Rafael Torres-Godomar  
Published: September 2019

La presente revisión tiene por finalidad actualizar nuestros conocimientos acerca de una patología que la estamos viendo cada vez con mayor frecuencia y que por sus características clínicas, fisiológicas, radiológicas é histopatológicas se presta a confusión. Se está dando a conocer la clasificación propuesta por un grupo de expertos internacionales así como nuevos conceptos sobre la patogenia y la manera de enfocar el diagnóstico y tratamiento de éstas entidades que a la fecha, superan las 200 enfermedades y que con un diagnóstico oportuno abrigamos la esperanza de mejorar el pronóstico y la calidad de vida de éstos pacientes.
Studi pengaruh perbedaan warna umpan buatan pancing gurita terhadap hasil tangkapan
Authors: Kurniawan Kholid , Manoppo Lefrand , Silooy Fanny , Luasunaung Alfret , Sompie Meta Sonya 
Published: September 2019

The western part of North Minahasa waters is mainly covers by coral reef with relatively large potential of fishery resources including Octopus. Fishermen of Budo village catches the Octopus by fishing gear known as sihoru or gara – gara boboca in local name with classified as trowling. The goals of this study are to analyze the influence of using different colors of typical bait released to fishing catch and to identity the catches species. Experimental method and T-Test wore using to analyze the data. The result indicated that the color differences not influence to the number of catches, which the analysis probability of brown and black colors is 0.6041, the brown and red is 0.4762, the black and red is 0.8455 which all of these numbers or higher than α0.05 = 2.2281. Based on this identification, Octopus cyanea is mainly catches.ABSTRAK Perairan Minahasa Utara bagian Barat pada umumnya merupakan hamparan batu karang yang memiliki potensi sumber daya perikanan yang relatif melimpah salah satunya adalah gurita (Octopus). Dalam memanfaatkan sumber daya ini masyarakat nelayan Desa Budo menangkap gurita menggunakan alat tangkap pancing yang disebut sihoru atau gara–gara boboca, alat tangkap ini adalah alat tangkap pancing jenis tonda. Tujuan dalam penelitian ini adalah menganalisis pengaruh penggunaan warna umpan terhadap jumlah hasil Tangkapan dan mengetahui spesies octopus hasil tangkapan. Metode yang digunakan dalam penelitan adalah eksperimental dan dianalisis menggunakan metode statistik Uji T. Dari penelitian ini diperoleh hasil nilai analisis P coklat hitam dan sebesar 0.6041, coklat dan merah sebesar 0.4762, hitam dan merah sebesar 0.8455 yang semua nilainya berada diatas α0.05 = 2.2281 dan dapat disimpulkan bahwa perlakuan warna umpan tidak berpengaruh terhadap hasil tangkapan. Berdasarkan hasil identifikasi gurita yang tertangkap adalah Octopus cyanea.
Kegiatan kesyahbandaran pangkalan pendaratan ikan di Kema Minahasa Utara
Authors: Rante Padang Arthur Welfi edo , Luasunaung Alfret , Kayadoe Mariana E 
Published: September 2019

Kema is one of the districts in North Minahasa Regency, which has a Fish Landing Base and also a local fish port area supplying marine fish. Kema Fish Landing Base is very helpful for Kema people in fish marketing. Fish port authority has a duty to check the document completeness and validity, the technical and nautical requirements of the ship for safety consideration, and set the cruise line inside the port area. The importance of the authority’s role in relation with the cruise safety is provided in Indonesian Law Numbered 17, 2008, concerning sailing cruise. The purpose of this study is to find out the obstacles encountered by the sahbandar and evaluate these constraints for the smooth running of the task. The research used descriptive method through interviews. Results showed that the port authority’s working performance in Kema was good.ABSTRAKKema adalah salah satu kecamatan di kabupaten Minahasa Utara, yang memiliki Pangkalan Pendaratan Ikan (PPI) dan juga merupakan pelabuhan perikanan lokal yang memasok ikan laut. Pangkalan Pendaratan Ikan Kema sangat membantu warga Kema untuk kelancaran proses penjualan ikan hasil tangkapan. Syahbandar perikanan memiliki tugas memeriksa kelengkapan dan keabsahan dokumen, memeriksa persyaratan teknis dan nautis kapal dari aspek keselamatan, dan mengatur alur pelayaran di dalam area pelabuhan. Pentingnnya peran syahbandar dalam keselamatan pelayaran yang tercantum pada undang-undang nomor 17 tahun 2008 tentang pelayaran. Tujuan penelitian ini yakni mengetahui kendala yang dihadapi syahbandar dan mengevaluasi kendala tersebut untuk kelancaran tugas. Penelitian ini menggunakan metode deskriptif dari data hasil wawancara. Hasil penelitian menunjukan bahwa tugas dan kinerja syahbandar Kema dapat digolongkan baik berdasarkan jawaban responden.