bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early Detection and Management of Prader-Willi Syndrome in Egyptian Patients
Authors: El-Bassyouni Hala T. , Hassan Nagwa , Mahfouz Inas , Abd-Elnaby Azza E. , Mostafa Mostafa I. , Tosson Angie M.S. 
Published: August 2019

AbstractPrader-Willi syndrome (PWS) is a distinct neurodevelopmental disorder associated with the deletion within the chromosomal 15q11-q13 region or uniparental disomy of chromosome 15. The etiologic heterogeneity of PWS makes it very difficult to establish uniform diagnostic methods which would result in the detection of most affected individuals. The objective was to report the clinical criteria and oro-dental features in PWS, to report the effect of diet and laser acupuncture on PWS and highlighted an easy effective method for early diagnosis of individuals with PWS. The study included seventeen cytogenetically proven individuals with Prader-Willi syndrome. These patients were subjected to meticulous history taking, clinical examination including oro-dental examination, bone densitometry and neuropsychiatric evaluation. They received laser acupuncture sessions in addition to nutrition intervention. All cases had characteristic facies, hypotonia and various psychosocial difficulties. Other criteria of PWS were present in different percentages. Karyotyping revealed deletion 15q11-q13 in 6 patients, and fluorescence in situ hybridization (FISH) revealed a microdeletion in 15q11–q13 in the other 11 patients. To our knowledge, partial ankyloglossia, median grooved tongue and hypodontia have not previously been reported in PWS patients. Laser acupuncture sessions and diet were effective in weight decline for PWS patients. Our study emphasizes the importance of early detection of PWS, laser sessions, diet restriction and oro-dental examination in the follow up of patients with Prader Willi syndrome.
MuSCA: a multi-scale source–sink carbon allocation model to explore carbon allocation in plants. An application to static apple tree structures
Authors: Reyes F , Pallas B , Pradal C , Vaggi F , Zanotelli D , Tagliavini M , Gianelle D , Costes E 
Published: August 2019

Abstract

Background and aims
Carbon allocation in plants is usually represented at a topological scale, specific to each model. This makes the results obtained with different models, and the impact of their scales of representation, difficult to compare. In this study, we developed a multi-scale carbon allocation model (MuSCA) that allows the use of different, user-defined, topological scales of a plant, and assessment of the impact of each spatial scale on simulated results and computation time.

Methods
Model multi-scale consistency and behaviour were tested on three realistic apple tree structures. Carbon allocation was computed at five scales, spanning from the metamer (the finest scale, used as a reference) up to first-order branches, and for different values of a sap friction coefficient. Fruit dry mass increments were compared across spatial scales and with field data.

Key Results
The model was able to represent effects of competition for carbon assimilates on fruit growth. Intermediate friction parameter values provided results that best fitted field data. Fruit growth simulated at the metamer scale differed of ~1 % in respect to results obtained at growth unit scale and up to 60 % in respect to first order branch and fruiting unit scales. Generally, the coarser the spatial scale the more predicted fruit growth diverged from the reference. Coherence in fruit growth across scales was also differentially impacted, depending on the tree structure considered. Decreasing the topological resolution reduced computation time by up to four orders of magnitude.

Conclusions
MuSCA revealed that the topological scale has a major influence on the simulation of carbon allocation. This suggests that the scale should be a factor that is carefully evaluated when using a carbon allocation model, or when comparing results produced by different models. Finally, with MuSCA, trade-off between computation time and prediction accuracy can be evaluated by changing topological scales.
A New Construction for Linkable Secret Handshake
Authors: Tian Yangguang , Li Yingjiu , Deng Robert H , Li Nan , Yang Guomin , Yang Zheng 
Published: August 2019

Abstract
In this paper, we introduce a new construction for linkable secret handshake that allows authenticated users to perform handshake anonymously within allowable times. We define formal security models for the new construction, and prove that it can achieve session key security, anonymity, untraceability and linkable affiliation-hiding. In particular, the proposed construction ensures that (i) anyone can trace the real identities of dishonest users who perform handshakes for more than k times; and (ii) an optimal communication cost between authorized users is achieved by exploiting the proof of knowledges.
Immunosuppressive therapy to reduce mitral regurgitation in Libman–Sacks endocarditis: a case report
Authors: Ishizu Kenichi , Isotani Akihiro , Yamaji Kyohei , Ando Kenji 
Published: August 2019

Abstract

Background
Libman–Sacks endocarditis is a cardiac manifestation of systemic lupus erythematosus (SLE) and is characterized by non-bacterial verrucous vegetations, causing valvular stenosis and/or regurgitation. The effectiveness of immunosuppressive therapy for valve dysfunction due to Libman–Sacks endocarditis has not been reported.

Case summary
A 67-year-old woman with a history of chronic atrial fibrillation was emergently admitted with acute decompensated heart failure. Transoesophageal echocardiogram revealed severe mitral regurgitation (MR) due to oedematous thickening and poor coaptation of the medial edge of A2/P2 segments and the lateral edge of A3/P3 segments. Serial blood culture results were negative, suggesting bacterial infective endocarditis to be a less likely cause of valvular damage. Because the patient developed photosensitivity, livedo reticularis, and pancytopenia, Libman–Sacks endocarditis with rapidly progressive SLE was diagnosed on the basis of positive test results of anti-double-stranded DNA-IgG and its complement titer. Two months after, immunosuppressive therapy including corticosteroids, a transoesophageal echocardiogram revealed thinning of the degenerative mitral valve leaflets and a reduction of MR from severe to mild.

Discussion
Corticosteroid therapy for Libman–Sacks endocarditis reportedly increases the extent of fibrosis and scarring of the valve leaflets, resulting in worse valve function. In our patient, MR decreased from severe to mild after corticosteroid therapy. Because low-echoic thickening of the mitral valve leaflets suggested acute oedematous changes without scarring and fibrosis and other clinical symptoms of SLE rapidly progressed, early initiation of immunosuppressive therapy for Libman–Sacks endocarditis lead to a benign clinical course in our patient.
At Least Something: The UN Special Committee on the Problem of Hungary, 1957–1958
Authors: Lieblich Eliav 
Published: August 2019

Abstract
In late 1956, the United Nations (UN) faced a remarkable test, as the Soviet Union invaded and crushed a burgeoning rebellion in Hungary, then a Soviet satellite. After the Soviet Union disregarded repeated UN calls to withdraw, the UN General Assembly established, in January 1957, a Commission of Inquiry (COI) to investigate the crisis. This article explores the forgotten story of the Special Committee on Hungary as a case study for the effects of COIs. This commission is of special interest for several reasons. Namely, it was one of the first mandated by a UN body to investigate a specific conflict, not least a Cold War struggle, in which a superpower was directly involved. Furthermore, it was clear from the beginning that the Committee was not likely to compel, in itself, the Soviet Union to change its behaviour. Moreover, 1956 was a time of global political transformation, as the non-aligned movement emerged as a key player in UN politics and, accordingly, became a target in the Cold War battle for influence. Under such circumstances, the effects of COIs are complex and difficult to gauge. While the Committee did not lead to the Soviet Union’s withdrawal from Hungary, it had many unforeseen and conflicting effects. These are grouped into two categories – effects relating mainly to times of ideological conflict and political transformation and effects that relate to parallel multilateral efforts and institutional dynamics. Among other effects, the article demonstrates how, under such political circumstances, COIs can create new points of contention and cause backlash precisely from those that they seek to influence. Having cascading and conflicting effects, the central conclusion is that COIs do not lend themselves easily to clean and linear theories. Recognition of the field’s inherent complexity is therefore needed in any attempt to study this international phenomenon.
The Unintended Consequences of the Goldstone Commission of Inquiry on Human Rights Organizations in Israel
Authors: Khoury-Bisharat Hala 
Published: August 2019

Abstract
Scholarly writings on internationally constituted commissions of inquiry (COIs), as outlined in the introduction to this symposium, give inadequate attention to the effects that they might have on local disputes that these bodies are often created to address. The United Nations Fact-Finding Mission on the Gaza Conflict (2009), popularly known as the Goldstone Commission, had unintended and unforeseen consequences at the domestic level. Specifically, the Commission caused a severe backlash against human rights organizations in Israel (IsHROs). This article analyses the backlash against the Commission and the effect of that backlash on human rights organizations and human rights advocacy in Israel and the Occupied Palestinian Territory in the first few years after the release of the Goldstone report. This case study reveals how a government can use a COI intervention in an ongoing conflict to deflect criticism against it and to delegitimize local human rights organizations and, as a result, to intensify enemy–friend dynamics within a conflict. The findings of this case study thus challenge the assumption of much of the socio-legal literature that the interaction of international human rights institutions with domestic actors leads to positive human rights change. But the case study also adds a new dimension to the academic and policy literature that has been critical of the international human rights enterprise in recent years. Despite delegitimization campaigns, international funding has increased for many IsHROs, and, eventually, some groups have become even more visible and have enjoyed, internationally, a higher reputation and greater credibility. The Commission’s experience thus demonstrates that the establishment of COIs in deeply divided conflict societies can have negative, as well as positive, implications on human rights.
A reappraisal of the H–κ stacking technique: implications for global crustal structure
Authors: Ogden C S , Bastow I D , Gilligan A , Rondenay S 
Published: August 2019

SUMMARYH–κ stacking is used routinely to infer crustal thickness and bulk-crustal VP/VS ratio from teleseismic receiver functions. The method assumes that the largest amplitude P-to-S conversions beneath the seismograph station are generated at the Moho. This is reasonable where the crust is simple and the Moho marks a relatively abrupt transition from crust to mantle, but not if the crust–mantle transition is gradational and/or complex intracrustal structure exists. We demonstrate via synthetic seismogram analysis that H–κ results can be strongly dependent on the choice of stacking parameters (the relative weights assigned to the Moho P-to-S conversion and its subsequent reverberations, the choice of linear or phase-weighted stacking, input crustal P-wave velocity) and associated data parameters (receiver function frequency content and the sample of receiver functions analysed). To address this parameter sensitivity issue, we develop an H–κ approach in which cluster analysis selects a final solution from 1000 individual H–κ results, each calculated using randomly selected receiver functions, and H–κ input parameters. 10 quality control criteria that variously assess the final numerical result, the receiver function data set, and the extent to which the results are tightly clustered, are used to assess the reliability of H–κ stacking at a station. Analysis of synthetic data sets indicates H–κ works reliably when the Moho is sharp and intracrustal structure is lacking but is less successful when the Moho is gradational. Limiting the frequency content of receiver functions can improve the H–κ solutions in such settings, provided intracrustal structure is simple. In cratonic Canada, India and Australia, H–κ solutions generally cluster tightly, indicative of simple crust and a sharp Moho. In contrast, on the Ethiopian plateau, where Palaeogene flood-basalts overlie marine sediments, H–κ results are unstable and erroneous. For stations that lie on thinner flood-basalt outcrops, and/or in regions where Blue Nile river incision has eroded through to the sediments below, limiting the receiver function frequency content to longer periods improves the H–κ solution and reveals a 6–10 km gradational Moho, readily interpreted as a lower crustal intrusion layer at the base of a mafic (VP/VS = 1.77–1.87) crust. Moving off the flood-basalt province, H–κ results are reliable and the crust is thinner and more felsic (VP/VS = 1.70–1.77), indicating the lower crustal intrusion layer is confined to the region covered by flood-basaltic volcanism. Analysis of data from other tectonically complex settings (e.g. Japan, Cyprus) shows H–κ stacking results should be treated cautiously. Only in regions of relatively simple crust can H–κ stacking analysis be considered truly reliable.
Celebrating a New Division of Botany at SICB: An Introduction to the Integrative Plant Biology Symposium
Authors: Matthew Ogburn R , Edwards Erika J 
Published: August 2019

Abstract
The Society for Integrative and Comparative Biology (SICB) should, in theory, be a home for scientists working across the entire Tree of Life. In practice, SICB has remained principally a society that supports integrative zoological research. Here we highlight a broad collection of what we consider to the best in integrative and comparative plant biology, gathered together for a special symposium at the 2019 SICB meeting. This symposium and special issue mark the initiation of a new Division of Botany within SICB, which we hope will usher in a new era of SICB where botanists and zoologists engage, collaborate, and celebrate together in this especially creative period of integrative and comparative biology.
Modeling thermal conductivity of Ag/water nanofluid by applying a mathematical correlation and artificial neural network
Authors: Ramezanizadeh Mahdi , Alhuyi Nazari Mohammad 
Published: August 2019

Abstract
Due to the significance importance of effective thermal conductivity of heat transfer fluids in various renewable energy system, such as geothermal and solar thermal plants, using naofluids can result in augment in the efficiency. Metallic nano particles dispersion in a pure fluid leads to considerable enhancement in the thermal conductivity. The improvement in the thermal conductivity is dependent on various factors. In the present research, two machine learning algorithms, a correlation and Group Method of Data Handling, are applied to predict thermal conductivity of silver/water nanofluid. Temperature, concentration and size of solid particles are considered as the input data. According to statistical comparison of the models, employing GMDH artificial neural network results in more precise and appropriate model. The coefficients of correlation, R-squared values, for the proposed correlation and ANN-based models are 0.948 and 0.99 respectively.
Measuring Populism across Nations: Testing for Measurement Invariance of an Inventory of Populist Attitudes
Authors: Wettstein Martin , Schulz Anne , Steenbergen Marco , Schemer Christian , Müller Philipp , Wirz Dominique S , Wirth Werner 
Published: August 2019

Abstract
The rising voter support for populist parties in Western Democracies in recent years has incited academic interest in populist voters and attitudes connected to the voting propensity of populist actors. In line of this research, numerous scales to measure populist attitudes among voters have been proposed. In most cases, however, the measurement of populist attitudes was tailored to specific countries and its applicability to cross-national research on populism was not assessed. This article uses a cross-national survey to assess the measurement invariance, reliability, and validity of a deductively developed inventory for populist attitudes. The findings suggest that there is a common attitudinal base to left- and right-wing populism which may be measured reliably and invariantly across nations.
Supporting the use of standardized nursing terminologies with automatic subject heading prediction: a comparison of sentence-level text classification methods
Authors: Moen Hans , Hakala Kai , Peltonen Laura-Maria , Suhonen Henry , Ginter Filip , Salakoski Tapio , Salanterä Sanna 
Published: August 2019

Abstract

Objective
This study focuses on the task of automatically assigning standardized (topical) subject headings to free-text sentences in clinical nursing notes. The underlying motivation is to support nurses when they document patient care by developing a computer system that can assist in incorporating suitable subject headings that reflect the documented topics. Central in this study is performance evaluation of several text classification methods to assess the feasibility of developing such a system.

Materials and Methods
Seven text classification methods are evaluated using a corpus of approximately 0.5 million nursing notes (5.5 million sentences) with 676 unique headings extracted from a Finnish university hospital. Several of these methods are based on artificial neural networks. Evaluation is first done in an automatic manner for all methods, then a manual error analysis is done on a sample.

Results
We find that a method based on a bidirectional long short-term memory network performs best with an average recall of 0.5435 when allowed to suggest 1 subject heading per sentence and 0.8954 when allowed to suggest 10 subject headings per sentence. However, other methods achieve comparable results. The manual analysis indicates that the predictions are better than what the automatic evaluation suggests.

Conclusions
The results indicate that several of the tested methods perform well in suggesting the most appropriate subject headings on sentence level. Thus, we find it feasible to develop a text classification system that can support the use of standardized terminologies and save nurses time and effort on care documentation.
Making connections: nationwide implementation of video telehealth tablets to address access barriers in veterans
Authors: Zulman Donna M , Wong Emily P , Slightam Cindie , Gregory Amy , Jacobs Josephine C , Kimerling Rachel , Blonigen Daniel M , Peters John , Heyworth Leonie 
Published: August 2019

Abstract

Background
Video telehealth technology has the potential to enhance access for patients with clinical, social, and geographic barriers to care. We evaluated the implementation of a US Department of Veterans Affairs (VA) initiative to distribute tablets to high-need Veterans with access barriers.

Methods
In this mixed methods implementation study, we examined tablet adoption (ie, facility-level tablet distribution rates and patient-level tablet utilization rates) and reach (ie, sociodemographic and clinical characteristics of tablet recipients) between 5/1/16 and 9/30/17. Concurrently, we surveyed 68 facility telehealth coordinators to determine the most common implementation barriers and facilitators, and then conducted interviews with telehealth coordinators and regional leadership to identify strategies that facilitated tablet distribution and use.

Results
86 VA facilities spanning all 18 geographic regions, distributed tablets to 6 745 patients. Recipients had an average age of 56 years, 53% lived in rural areas, 75% had a diagnosed mental illness, and they had a mean (SD) of 5 (3) chronic conditions. Approximately 4 in 5 tablet recipients used the tablet during the evaluation period. In multivariate logistic regression, tablet recipients were more likely to use their tablets if they were older and had fewer chronic conditions. Implementation barriers included insufficient training, staffing shortages, and provider disinterest (described as barriers by 59%, 55%, and 33% of respondents, respectively). Site readiness assessments, local champions, licensure modifications, and use of mandates and incentives were identified as strategies that may influence widespread implementation of home-based video telehealth.

Conclusion
VA’s initiative to distribute video telehealth tablets to high-need patients appears to have successfully reached individuals with social and clinical access barriers. Implementation strategies that address staffing constraints and provider engagement may enhance the impact of such efforts.
The ‘upper deck view’ improves visualization during acetabuloplasty without chondro-labral detachment
Authors: Ortiz-Declet Victor , Mu Brian H , Yuen Leslie C , Maldonado David R , Chen Austin W , Lall Ajay C , Domb Benjamin G 
Published: August 2019

Abstract
The ‘upper deck’ view is an arthroscopic perspective which visualizes the labral–osseous junction without detachment of the chondro-labral junction. The aim of this study was to evaluate the utility of the ‘upper deck’ view in preventing incomplete acetabuloplasty. Data were prospectively collected from September 2016 to November 2016 for all hip arthroscopies. We recorded the amount and clock-face of residual pincer-lesion acetabular bone resected using the ‘upper deck’ view. We noted whether this residual pincer-lesion acetabular bone was visible fluoroscopically, as well as the amount and clock-face of the overall acetabuloplasty. During the study period, 87 hip arthroscopies were performed; 50 met the inclusion criteria. Forty-six (92%) patients had residual pincer-lesion acetabular bone after completion of the acetabuloplasty resected from the bird's eye view. In all such cases the residual pincer-lesion acetabular bone was not visible under fluoroscopy and could only be detected using this specific view. The average maximum resection for the acetabuloplasty was 2.1 ± 0.9 and 1.4 ± 0.5 mm (P = 0.16) for resection of residual pincer-lesion acetabular bone. The ‘upper deck’ view provides the ability to decrease the risk of incomplete acetabuloplasty, due to the high likelihood (92%) of a residual beak of pincer-lesion acetabular bone when this view is not used during rim trimming.
Bhakti’s Visualities of Connection in the Arts Today
Authors: Pechilis Karen 
Published: August 2019

AbstractRecently, artists in drama, dance, and contemporary art have visually evoked bhakti through their engagement with the historically remote Tamil bhakti poet-saint Kāraikkāl Ammaiyār. For centuries, bhakti in regional languages has been deeply intertwined with the arts, with its emphasis on personal engagement, emotionally inflected expressiveness and declarative performance. The bhakti poet-saints’ own words and deeds promoted a visuality of connection that enabled new and diverse participation in religio-social authority. Drawing on a resonant yet transformed mode of this visuality of connection, the arts today assert that Kāraikkāl Ammaiyār is a socially relevant figure—teacher, feminist, global spiritual icon—grounded in her own time and as speaking to ours. The contemporary arts’ mediation of classical ideas and contemporary concerns through visualities of connection that engage audiences today suggests a challenge to contemporary museum culture, which shares with the arts immersive display, yet grapples with envisioning a visuality of connection that provides a global audience today with an experience of classical art of India as both accessible and relevant.