bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nuclear Spin Singlet States in Photoactive Molecules: From Fluorescence/NMR Bimodality to a Bimolecular Switch for Spin Singlet States
Authors: Yang Shengjun , McCormick Jeffrey , Mamone Salvatore , Bouchard Louis‐S. , Glöggler Stefan 
Published: January 2019

AbstractNuclear spin singlet states are silent states in nuclear magnetic resonance (NMR). However, they can be probed indirectly and offer great potential for the development of contrast agents for magnetic resonance imaging (MRI). Introduced here are two novel concepts: Firstly, the bimodal NMR/fluorescence properties of 13C2‐tetraphenylethylene. It possesses a long‐lived singlet state in organic solvents, and it shortens upon the addition of water. This simultaneously increases the aggregation‐induced emission (AIE) of the molecule, resulting in a substantial enhancement of fluorescence. Secondly, introduced is a bimolecular switch for singlet states based on 3‐2H‐coumarin containing an isolated proton. Upon UV‐light exposure, a dimer forms, leading to a coupling between two previously isolated protons. A nuclear spin singlet state can now be populated. Excitation with a wavelength of 254 nm results in partial ring cleavage of the molecule back to its monomer.
Robust Superhydrophobic/Superoleophilic Wrinkled Microspherical MOF@rGO Composites for Efficient Oil–Water Separation
Authors: Gu Jiahui , Fan Hongwei , Li Chunxi , Caro Jürgen , Meng Hong 
Published: January 2019

AbstractGraphene/MOF‐based composite materials in three‐dimensional (3D) architectures are promising for the treatment of oil‐containing wastewater by absorption owing to their intrinsic properties of graphene and metal‐organic frameworks (MOFs), such as high porosity, ultralow density, and facilely tailored superwettability. In this study, novel wrinkled 3D microspherical MOF@rGO composites with both superhydrophobic and superoleophilic properties were developed by embedding MOF nanoparticles between graphene oxide (GO) nanosheets, followed by high‐temperature reduction self‐assembly. The microspherical composites feature a unique micro/nano hierarchy consisting of crumpled reduced GO (rGO) nanosheets intercalated with well‐dispersed MOF nanoparticles. Combined with the superwettability and abundant meso/microporosity, the peculiar architectures of wrinkled ZIF‐8@rGO microspheres show very fast absorption rates and high sorption selectivity for organic solvents and oils from water.
Hydrophobic Metal Halide Perovskites for Visible‐Light Photoredox C−C Bond Cleavage and Dehydrogenation Catalysis
Authors: Hong Zonghan , Chong Wee Kiang , Ng Andrew Yun Ru , Li Mingjie , Ganguly Rakesh , Sum Tze Chien , Soo Han Sen 
Published: January 2019

AbstractTwo‐dimensional lead and tin halide perovskites were prepared by intercalating the long alkyl group 1‐hexadecylammonium (HDA) between the inorganic layers. We observed visible‐light absorption, narrow‐band photoluminescence, and nanosecond photoexcited lifetimes in these perovskites. Owing to their hydrophobicity and stability even in humid air, we applied these perovskites in the decarboxylation and dehydrogenation of indoline‐2‐carboxylic acids. (HDA)2PbI4 or (HDA)2SnI4 were investigated as photoredox catalysts for these reactions, and quantitative conversion and high yields were observed with the former.
A Noncovalent Fluorescence Turn‐on Strategy for Hypoxia Imaging
Authors: Geng Wen‐Chao , Jia Shaorui , Zheng Zhe , Li Zhihao , Ding Dan , Guo Dong‐Sheng 
Published: January 2019

AbstractHypoxia plays crucial roles in many diseases and is a central target for them. Present hypoxia imaging is restricted to the covalent approach, which needs tedious synthesis. In this work, a new supramolecular host–guest approach, based on the complexation of a hypoxia‐responsive macrocycle with a commercial dye, is proposed. To exemplify the strategy, a carboxyl‐modified azocalix[4]arene (CAC4A) was designed that binds to rhodamine 123 (Rho123) and quenches its fluorescence. The azo groups of CAC4A were selectively reduced under hypoxia, leading to the release of Rho123 and recovery of its fluorescence. The noncovalent strategy was validated through hypoxia imaging in living cells treated with the CAC4A–Rho123 reporter pair.
Superior activity of Ce‐HZSM‐5 catalyst for catalytic oxidation of arsine at low oxygen
Authors: Xie Yibing , Wang Langlang , Ning Ping , Wang Xueqian , Wang Qi , Zhang Yingjie , Wang Mengyu 
Published: January 2019

A series of Ce modified catalysts were prepared using equivalent‐volumetric ultrasonic impregnation method for AsH3 removal. The performance of catalytic oxidation of AsH3 under dynamic conditions was studied under different synthesis and reaction conditions. Through screening tests, the optimum catalyst was impregnated by 10 wt.% Ce (CH3COO)3 precursor and subsequently calcinated at 550 °C. When the reaction temperature reached 170 °C, the Ce‐HZSM‐5 catalyst could maintain an oxidation efficiency of over 90% in 82 hrs. Furthermore, the chemical structure and properties of the catalyst and its catalytic oxidation mechanism with AsH3 were analyzed using SEM‐EDS, BET, XRD, XPS, H2‐TPR and FT‐IR. The results showed that Ce mainly existed on the catalyst surface in the forms of Ce4+ and Ce3+. In the reaction process, the chemisorbed oxygen played a key role in the transformation between the two valence states. AsH3 was firstly oxidized to elemental As with the participation of lattice oxygen. Then, the elemental As was partially blown into the rear part of the adsorption column along with the air flow and subsequently, de‐sublimed on the column wall. Herein, the elemental As remained on the surface of Ce‐HZSM‐5 catalyst, which would further oxidize to As2O3. For the recovery of As, Ce‐HZSM‐5 proved to be a promising catalyst in AsH3 removal.Highlights

The CeOx modified HZSM‐5 catalyst was used to catalytic oxidation of AsH3.
The Ce‐HZSM‐5 catalyst could maintain over 90% oxidation efficiency in 82 hrs.
AsH3 was catalytic oxidized to elemental As and H2O on the catalyst surface and the As can be collected.
The As adsorbed on the catalyst surface can be oxidized to As2O3 but cannot be further oxidized to As2O5.
Preparation and analysis of poly(l‐lactic acid) composites with oligo(d‐lactic acid)‐grafted cellulose
Authors: Rahaman Md. Hafezur , Rana Md. Masud , Gafur Mohammad Abdul , Mohona Anika Amir 
Published: January 2019

ABSTRACTα‐Cellulose extracted from jute fiber was grafted with oligo(
d‐lactic acid) (ODLA) via a graft polycondensation reaction in the presence of para‐toluene sulfonic acid and potassium persulfate in toluene at 130 °C for 9 h under 380 mmHg. ODLA was synthesized by the ring‐opening polymerization of
d‐lactides in the presence of stannous octoate (0.03 wt % lactide) and
d‐lactic acid at 140 °C for 10 h. Composites of poly(
l‐lactic acid) (PLLA) with the ODLA‐grafted α‐cellulose were prepared by the solution‐mixing and film‐casting methods. The grafting of ODLA onto α‐cellulose was confirmed by Fourier transform infrared (FTIR) spectroscopy and scanning electron microscopy (SEM). The analysis of the composites was performed with FTIR spectroscopy, SEM, wide‐angle X‐ray diffraction, and thermogravimetric analysis. The distribution of the grafted α‐cellulose in the composites was uniform and showed better compatibility with PLLA through intermolecular hydrogen bonding. Only homocrystalline structures of PLLA were present in the composites, and the thermal stability increased with increasing percentage of grafted α‐cellulose. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47424.
Effect of microstructural arrangement of MDI‐based polyurethanes on their photoproperties
Authors: Senevirathna Sandhya Rani , Amarasinghe D. A. S. , Karunaratne Veranja , Koneswaran Masilamani , Karunanayake Laleen 
Published: January 2019

ABSTRACTAmong the vast variety of polyurethane applications, several applications use the fluorescing nature of some of the polyurethanes. Even though 4,4′‐methylenebis(phenylisocyanate) (MDI)‐based polyurethanes fluoresce, their applications are rare because of the lack of knowledge about the fluorescence behavior of these polymers. In this study, the fluorophores responsible for the emission spectra of MDI‐based polyurethanes were identified, and their emission behavior was investigated. When excited, these polymers produce two prominent emission peaks located at 356 nm and 423 nm, which are assigned to the radiative relaxation of excited isolated hard segments and excited crystalline hard segment bundles of the MDI‐based polyurethanes, respectively. It was found that both chromophores can be excited by 293 nm UV radiation. The observed intensity variations of the two peaks with exposure time were attributed to the localized UV melting‐assisted migration of isolated hard segments. This migration facilitates the formation of crystalline hard segments. As the two chromophore populations are inversely propositional to each other, the relative intensity of the two emission peaks varies with UV exposure in a similar manner. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47431.
Eudragit E100/poly(ethylene oxide) electrospun fibers for DNA removal from aqueous solution
Authors: Barbosa Jaderson de A. B. , de França Chirles A. , Gouveia João José de S. , Gouveia Gisele V. , da Costa Mateus M. , de Oliveira Helinando P. 
Published: January 2019

ABSTRACTThe development of new strategies for production of low‐cost deoxyribonucleic acid (DNA) adsorbents based on electrospun fibers of block copolymers [Eudragit E‐100/poly(ethylene oxide) (PEO)] is a promising way for fast retrieval of free of degradation double‐stranded DNA chains from aqueous solution. The adsorption takes place through electrostatic interaction between DNA and oppositely charged electrospun fibers that provide high surface area for DNA adsorption. The adsorption capacity observed for electrospun fibers of Eudragit E100/PEO (considering as target molecules the salmon sperm DNA) was in order of 44.31 mg g−1, following the Langmuir model in a typical adsorption at solid/liquid interface (pseudo‐second‐order model), that characterizes the electrospun fibers as promising templates for removal of biologic components and further use in molecular biology techniques, as DNA amplification by polymerase chain reaction. The reuse and integrity of membranes after long period of adsorption were tested, confirming the potential of material as adsorbent. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47479.
Effect of the inflation strategy on the piezoelectric response of cellular poly(vinylidene fluoride) ferroelectret
Authors: Jahan Nusrat , Mighri Frej , Rodrigue Denis , Ajji Abdellah 
Published: January 2019

ABSTRACTCellular poly(vinylidene fluoride) (PVDF)‐montmorillonite (MMT)‐calcium carbonate (CaCO3) based piezoelectret films were produced using uniaxial stretching and various gas diffusion expansion (GDE) treatments followed by corona charging. The cross section micrographs revealed that a cellular structure was developed at the interface between the solid CaCO3 particles and the polymer matrix. Sample characterization showed that the piezoelectric coefficient (d33) was a function of the external gas pressure and treatment temperature, as well as the way they were applied. The results also showed that the maximum d33 was obtained when the inflation pressure was increased stepwise from 3 to 5 MPa at a constant treatment temperature of 130°C for a certain period of time. Finally, the overall electromechanical performance of the cellular PVDF piezoelectrets is discussed in terms of the GDE procedure and the developed microstructures. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47540.
Effect of Bone Marrow‐Derived Mesenchymal Stem Cells on Cochlear Function in an Experimental Rat Model
Authors: Mittal Rahul , Ocak Emre , Zhu Angela , Perdomo Mario M. , Pena Stefanie A. , Mittal Jeenu , Bohorquez Jorge , Eshraghi Adrien A. 
Published: January 2019

ABSTRACTMesenchymal stem cell (MSC) therapy is an emerging treatment modality for various human diseases. Although induced pluripotent stem cells have been explored for the restoration of hearing, the potential of MSCs as a therapeutic strategy for various cochlear insults is not precisely known. MSCs possess anti‐inflammatory, anti‐apoptotic and neuroprotective properties, making them an attractive target for the treatment of inner ear disorders such as hair cell damage in response to inflammation. Most of the previous studies have used immunosuppression or the complex surgical techniques to deliver stem cells into the cochlea. However, no information is available regarding the biocompatibility and safety of MSCs in the inner ear in immunocompetent cochlea. The aim of the present study was to determine the effect of non‐surgical administration of rodent bone marrow derived MSCs (BM‐MSCs) through transtympanic delivery on the cochlear function and to assess any adverse effects on the auditory system employing a rat model without immunosuppression. We observed that the transtympanic administration of BM‐MSCs has no significant effect on the hearing thresholds as determined by auditory brainstem response and distortion product otoacoustic emissions. Histopathological examination revealed no recruitment of inflammatory leukocytes and edema in the cochlea of BM‐MSCs administrated rats. The results of this study suggest that transtympanic administration of BM‐MSCs is safe and can be explored in providing otoprotection against cochlear insults. Anat Rec, 303:487–493, 2020. © 2019 American Association for Anatomy
RuII and IrIII Complexes Containing ADA and DAD Triple Hydrogen Bonding Motifs: Potential Tectons for the Assembly of Functional Materials
Authors: McKay Aidan P. , Mapley Joseph I. , Gordon Keith C. , McMorran David A. 
Published: January 2019

AbstractThe synthesis and characterisation of a series of [RuII(bpy)2L] and [Ir(ppy)2L] complexes containing ligands L with the potential to engage in triple hydrogen bonding interactions is described. L1 and L2 comprise pyridyl triazole chelating units with pendant diaminotriazine units, capable of donor‐acceptor‐donor (DAD) hydrogen bonding, while L3 and L4 contain ADA hydrogen bonding units proximal to N^N and N^O cleating sites, respectively. X‐ray crystallography shows the L1 and L2 containing RuII complexes to assemble via
hydrogen bonding dimers, while [RuII(bpy)2L4] assembles via extended hydrogen bonding motifs to form one dimensional chains. By contrast, the expected hydrogen bonding patterns are not observed for the RuII and IrIII complexes of L3. Spectroscopic studies show that the absorption spectra of the complexes result from combinations of MLCT and LLCT transitions. The L1 and L2 complexes of IrIII and RuII complexes are emissive in the solid state and it seems likely that hydrogen bonding to complementary species may facilitate tuning of their 3ILCT emission. Low frequency Raman spectra provide further evidence for ordered interactions in the solid state for the L4 complexes, consistent with the results from X‐ray crystallography.
Effect of a Pendant Acceptor on Thermally Activated Delayed Fluorescence Properties of Conjugated Polymers with Backbone‐Donor/Pendant‐Acceptor Architecture
Authors: Yang Yike , Li Kuofei , Wang Chenxu , Zhan Hongmei , Cheng Yanxiang 
Published: January 2019

AbstractThree sets of conjugated polymers with backbone‐donor/pendant‐acceptor architectures, named PCzA3PyB, PCzAB2Py, and PCzAB3Py, are designed and synthesized. The three isomeric benzoylpyridine‐based pendant acceptor groups are 6‐benzoylpyridin‐3‐yl (3PyB), 4‐((pyridin‐2‐yl)carbonyl)phenyl (B2Py) and 4‐((pyridin‐3‐yl)carbonyl)phenyl (B3Py), whereas the identical backbone consists of 3,6‐carbazolyl and 2,7‐acridinyl rings. One acridine ring and each acceptor group constitute a definite thermally activated delayed fluorescence (TADF) unit, incorporated into the main chain of the polymers through the 2,7‐position of the acridine ring with the varied content. All of the polymers display legible TADF features with a short microsecond‐scale delayed lifetime (0.56–1.62 μs) and a small singlet/triplet energy gap (0.10–0.19 eV). Progressively redshifted emissions are observed in the order PCzAB3Py, PCzA3PyB, and PCzAB2Py owing to the different substitution patterns of the pyridyl group. Photoluminescence quantum yields can be improved by regulating the molar content of the TADF unit in the range 0.5–50 %. The non‐doped organic light‐emitting devices (OLEDs) fabricated by solution‐processing technology emit yellow‐green to orange light. The polymers with 5 mol % of the TADF unit exhibit excellent comprehensive electroluminescence performance, in which PCzAB2Py5 achieves a maximum external quantum efficiency (EQE) of 11.9 %, low turn‐on voltage of 3.0 V, yellow emission with a wavelength of 573 nm and slow roll‐off with EQE of 11.6 % at a luminance of 1000 cd m−2 and driving voltage of 5.5 V.
Neuroprotection of mangiferin against oxidative damage via arousing Nrf2 signaling pathway in PC12 cells
Authors: Peng Shoujiao , Hou Yanan , Yao Juan , Fang Jianguo 
Published: January 2019

AbstractAccumulating evidence demonstrates that oxidative stress is involved in the pathogenesis and progression of neurodegeneration. As NF‐E2‐related factor 2 (Nrf2) plays a crucial role in maintaining cellular redox homeostasis, small molecules with the ability in activation of Nrf2 pathway are promising neuroprotective agents. Mangiferin (Mg) is a xanthone glucoside extracted from mangoes and papayas, and has been reported to possess multiple pharmacological activities. In this study, we investigated neuroprotective effects of Mg in the neuron‐like rat pheochromocytoma cell line (PC12 cells). Mg scavenges different kinds of free radicals in vitro and attenuates hydrogen peroxide‐ or 6‐hydroxydopamine‐induced cell death. After treatment with Mg, a range of antioxidant genes governed by Nrf2 were upregulated, and the expressions and activities of these gene products were also elevated. Moreover, knockdown of Nrf2 antagonized the protective effect of Mg, indicating that Nrf2 is an essential factor in this cytoprotective process. In summary, our study demonstrates that Mg is a potent antioxidant that can provide neuroprotection against oxidative stress‐mediated damage of PC12 cells. © 2019 BioFactors, 45(3):381–392, 2019
Marital status and survival in patients with soft tissue sarcoma: A population‐based, propensity‐matched study
Authors: Zhang Shi‐long , Wang Wen‐rong , Liu Ze‐juan , Wang Zhi‐ming 
Published: January 2019

AbstractBackgroundMarital status serves as an independent prognostic factor for survival in a variety of cancers. However, its prognostic impact on soft tissue sarcoma (STS) has not yet been established.ObjectiveTo investigate the impact of marital status on survival outcomes among STS patients.MethodsA total of 18 013 STS patients diagnosed between 2004 and 2015 were extracted from Surveillance, Epidemiology, and End Results (SEER) database. The marital status was classified into married, divorced, widowed, and single. Kaplan‐Meier analysis and multivariate Cox proportional hazards regression analysis were conducted to establish the impact of marital status on the overall survival (OS) and cancer‐specific survival (CSS). Subgroup analyses were conducted based on age, SEER historic stage and surgery condition. Propensity score matching (PSM) was used to perform a 1:1 matched‐pair analysis to minimize the group differences caused by covariates.ResultsMarried patients enjoyed better 5‐year overall survival (OS) and 5‐year cancer‐specific survival (CSS), compared with patients who were divorced, widowed, and single, respectively. Multivariate Cox proportional hazards regression analysis revealed that marital status was an independent prognostic and protective factor for survival among STS patients, and unmarried status was associated with higher mortality hazards for both OS and CSS. Additionally, widowed individuals had the highest risks of overall and cancer‐specific mortality compared to other unmarried groups. In the subgroup analyses, similar associations were also found. Furthermore, marital status still remained an independent prognostic and protective factor for both OS and CSS even in 1:1 matched‐pair analysis.ConclusionsMarital status was an independent prognostic and protective factor for survival for STS patients. Widowed patients suffered the highest death risks among the unmarried groups.
Radiotherapy after surgery has significant survival benefits for patients with triple‐negative breast cancer
Authors: Yao Yi , Chu Yuxin , Xu Bin , Hu Qinyong , Song Qibin 
Published: January 2019

AbstractObjectivesThe value of adjuvant radiotherapy for triple‐negative breast cancer (TNBC) has been controversial recently. This study aims to clarify the influence of radiotherapy on the survival of TNBC patients after surgery based on a large population analysis.MethodsThe Surveillance, Epidemiology, and End Results (SEER) database was exploited to select eligible patients from 2010 to 2014. The categorical variables were examined by chi‐square tests. Breast cancer‐specific survival (BCSS) and overall survival (OS) were compared among patients who received or not received adjuvant radiotherapy after surgery by Kaplan‐Meier method with log‐rank test. Univariate and multivariate survival analysis of BCSS and OS were performed using the Cox proportional hazard model.ResultsTotally 22 802 patients were enrolled in this study, of which 10 905 patients received radiotherapy after surgery while 11 897 patients did not receive radiotherapy. Compared with those patients who did not receive radiotherapy, the radiation group had a larger proportion of tumor size <2.0 cm (45.8% vs 38.8%) and chemotherapy (82.5% vs 67.4%). The Kaplan‐Meier plots displayed that patients in the radiation group had better survival than the no radiation group in both BCSS and OS (P < 0.001, respectively). In univariate Cox analysis of BCSS, age 40‐60, married status, white and other race, chemotherapy, radiation, and surgery were associated with better survival (HR < 1, P < 0.05). Specifically, patients who received radiotherapy exhibited better BCSS (HR = 0.52, 95% CI = 0.48‐0.57, P < 0.001). After adjusting for confounding factors by multivariable Cox regression analysis, receipt of radiotherapy was still associated with improved BCSS (HR = 0.79, 95% CI = 0.72‐0.87, P < 0.001). Survival analysis of OS produced similar results. Generally, these data indicate that radiotherapy after surgery has significant survival benefits for the TNBC patients.ConclusionsThis study has confirmed the survival advantage of adjuvant radiotherapy for the TNBC patients. These findings may optimize the current individualized treatment decisions for this patient population.