bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and Preliminary Evaluation of a Varying-Speed Road Profiler
Authors: Guo Runhua , Yu Zhenzhou , Zhou Youjia 
Published: March 2019

Abstract
The International Roughness Index (IRI) has been widely used to characterize the road ride quality in the highway engineering community. IRI is commonly obtained via the longitudinal profile data collected by a high-speed inertial profiler. It is well known that the IRI value based on an inertial profiler can be biased under low-speed or varying-speed conditions. This stems from the inherent limitation of the accelerometer embedded in the measurement system. This study proposes a different approach to solving the problem by employing three-dimension laser scanning technology. Without relying on the accelerometer to offset the vehicle vertical dynamics/vibration, the new approach uses the measurement by a line laser to transfer the elevation along the driving direction. Following this principle, a road profiler was developed and installed on a host vehicle. A preliminary evaluation of the newly developed profiler was conducted on two urban road sections in Beijing. The elevation was focused on wavelength, IRI index, and repeatability analysis. The results showed that the proposed profiler could effectively capture road elevation and accurately characterize ride quality. It was indicated that this new equipment could serve as a useful tool to better accommodate the ride quality measurement under varying-speed data collection conditions, particularly in the urban environment.
Realized Genome Sharing in Heritability Estimation Using Random Effects Models
Authors: Wang Bowen , Thompson Elizabeth 
Published: March 2019

AbstractFor heritability estimation using a two-component random effects model, we provided formulas for the limiting distribution of the maximum likelihood estimate. These formulas are applicable even when the wrong measure of kinship is used to capture additive genetic correlation. When the model is correctly specified, we showed that the asymptotic sampling variance of heritability estimate is determined by both the study design and the extent of variation in the kinship measure that constitutes the additive genetic correlation matrix. When the correlation matrix is mis-specified, the extent of asymptotic bias depends additionally on how the fitted correlation matrix differs from the truth. In particular, we showed in a simulation study that estimating heritability using a population-based design and the classic GRM as the fitted correlation matrix can potentially contribute to the ”missing heritability” problem.
Genetic Dissection of Resistance to the Three Fungal Plant PathogensBlumeria graminis,Zymoseptoria tritici, andPyrenophora tritici-repentisUsing a Multiparental Winter Wheat Population
Authors: Stadlmeier Melanie , Jørgensen Lise Nistrup , Corsi Beatrice , Cockram James , Hartl Lorenz , Mohler Volker 
Published: March 2019

AbstractBread wheat (Triticum aestivum L.) is one of the world’s most important crop species. The development of new varieties resistant to multiple pathogens is an ongoing task in wheat breeding, especially in times of increasing demand for sustainable agricultural practices. Despite this, little is known about the relations between various fungal disease resistances at the genetic level, and the possible consequences for wheat breeding strategies. As a first step to fill this gap, we analyzed the genetic relations of resistance to the three fungal diseases – powdery mildew (PM), septoria tritici blotch (STB), and tan spot (TS) – using a winter wheat multiparent advanced generation intercross population. Six, seven, and nine QTL for resistance to PM, STB, and TS, respectively, were genetically mapped. Additionally, 15 QTL were identified for the three agro-morphological traits plant height, ear emergence time, and leaf angle distribution. Our results suggest that resistance to STB and TS on chromosome 2B is conferred by the same genetic region. Furthermore, we identified two genetic regions on chromosome 1AS and 7AL, which are associated with all three diseases, but not always in a synchronal manner. Based on our results, we conclude that parallel marker-assisted breeding for resistance to the fungal diseases PM, STB, and TS appears feasible. Knowledge of the genetic co-localization of alleles with contrasting effects for different diseases, such as on chromosome 7AL, allows the trade-offs of selection of these regions to be better understood, and ultimately determined at the genic level.
Influence of Home Environment on the Academic Performance of the Students in Some Selected Schools in Dekina Local Government Area in Kogi State, Nigeria
Authors: Anthonia Uloko 
Published: March 2019

This study investigates empirically the influence of home environment on the academic performance of the students in some selected schools in Dekina Local Government Area in Kogi State, Nigeria. The study was anchored on Charles Darwin Social Theory and Theory of Parent Involvement. The researcher used mainly primary data from a sample of 120 respondents obtained by the use of a well-structured questionnaire. The data collected were analyzed using multiple linear regression analysis. The probability value of the estimate was used for accepting and rejecting the hypotheses of the study. The result of the regression analysis indicates that a positive relationship exist between parents’ economic status (PES) and Students Academic Performance (SAP) in selected schools in Dekina Local Government Kogi State, Nigeria and the relationship is statistically significant (p<0.05). A positive relationship exist between parents educational background (PEB) and Students' Academic Performance (SAP) in selected schools in Dekina Local Government Kogi State, Nigeria and the relationship is statistically significant (p<0.05). Parental marital style (PMS) was negatively related to Students' Academic Performance (SAP) in selected schools in Dekina Local Government Kogi State, Nigeria. Home location of parent (HLP) was positively related to Students' Academic Performance (SAP) in selected schools in Dekina Local Government Kogi State, Nigeria and the relationship is statistically significant (p<0.05) and in line with a priori expectation. It was concluded that parents’ economic statuses, parental educational backgrounds, parental marital Styles, and home locations of parents all do have varying degrees of effects on the performance of students in the study area. It was recommended among others that illiterate parents should be encouraged to go to school, in that their literacy will enhance their children academic achievement in schools.
INDEFERIMENTO DO AUXÍLIO-DOENÇA/ AUXÍLIO-ACIDENTÁRIO DO EMPREGADO CONSIDERADO INAPTO PELO MÉDICO DA EMPRESA
Authors: Kroth Joseane Da Silva , Almeida Almiro Eduardo de 
Published: March 2019

O presente trabalho trata sobre a situação desumana a que o trabalhador é submetido quando há confronto entre a decisão da perícia médica do INSS e do médico do trabalho. Nesses casos, a autarquia previdenciária argumenta que o trabalhador já possui capacidade laborativa, enquanto o médico da empresa considera o trabalhador inapto para retornar às atividades laborativas. Aborda as consequências desta situação, tendo como principal a insegurança jurídica do trabalhador que, ao recorrer ao judiciário, permanece sem nenhuma fonte de renda até o momento da decisão judicial. O trabalho propõe três possíveis soluções para corrigir essa falha em nosso ordenamento jurídico: a competência da justiça do trabalho junto com a responsabilização da empresa quando for o médico do trabalho que proferir laudo médico errôneo; a criação de uma nova hipótese de interrupção contratual; e a interpretação ampliada das hipótesesde interrupção. Além disso, ressalta que perícias médicas com melhor qualidade previne essa situação, sendo o melhor para todos os envolvidos. Por fim, fala sobre a responsabilidade médica e social do perito.
A PROVA TESTEMUNHAL NO PROCESSO PENAL: ANÁLISE DAS FALSAS MEMÓRIAS NO ESTUPRO DE VULNERÁVEL
Authors: Otto Gabriela Magnus , Silveira Felipe Lazzari da 
Published: March 2019

O processo penal, como instrumento fundamental para a aplicação dodireito penal material e dimensionamento da pena, tem seus preceitoscalcados na aplicação de um sistema acusatório, com plena observânciados direitos das partes. Todavia, a realidade é que o processo penal pende mais para a utilização de um sistema inquisitório, e é através do modo de gestão da prova utilizado pelo julgador que se definirá a sistemática utilizada. O modelo de valoração das provas no processo penal brasileiro (livre convencimento motivado) é posto em questão, no presente trabalho, naqueles casos em que o processo dispõe apenas de prova testemunhal para apreciação do julgador. A fragilidade da memória, além da questão biológica temporal, será analisada sob o prisma da incidência do fenômeno das falsas memórias, em especial, e no seu maior campo de ocorrência, no caso do depoimento da criança vítima de estupro de vulnerável. Na busca por meios que controlem os prejuízos para o processo advindos de um depoimento danoso, que reforcem a segurança jurídica dos julgamentos, buscamos conhecer o projeto Depoimento Sem Dano que visa justamente a proteção dos infantes no âmbito judicial, bem como a redução de relatos inverídicos.
Kelsen, the New Inverted Pyramid and the Classics of Constitutional Law
Authors: Riofrío Juan Carlos 
Published: March 2019

The present study overhauls Hans Kelsen’s thesis of the traditional normative pyramid, in order to accommodate the most outstanding doctrinal contributions of the last century to it. For the purpose, the Essay proceeds as follows: (i) the shortcomings of the first version of the pyramid, found in Kelsen’s Pure Theory of Law and on Adolf Merkl’s contributions, are detected; (ii) new key concepts of the Aristotelian-Thomistic metaphysics are introduced, this will allow us to upgrade the theory of the staggered legal system; (iii) unity and order of the legal system are briefly analyzed; (iv) a staggered legal pyramid is redesigned, with a gradual reduction of the juridical space; and finally, (v) the theories of Kelsen, Merkl, and several of the most influential doctrinarians of law (e.g., Jhering, Radbruch, Rorty, Ross, Kelsen, Holmes, Hägerström, Olivecrona, Hart, MacCormick, Dworkin, among others) are tested, to see if their ideas fit in the new theory.This upgrade of the traditional theory arises from a significant shift in the philosophical basis. The first pyramid was elaborated by Kelsen and Merkl under the tenets of neoKantian metaphysics. On the other hand, the methodology and the basic ideas behind this study are those of the Aristotelian-Thomistic metaphysics. It moves from an idealistic metaphysics to a traditional realistic metaphysics, so neglected in recent centuries. The inverted pyramid theory, formulated here, is the product of many previous works. Many of them have been published in different international journals.
Content and Characteristics of a Cross-Border Construction Contract
Authors: Goddard I. A. 
Published: March 2019

The paper deals with the problems of legal regulation of relations arising due to a cross-border construction contract. The author substantiates the presence of the characteristics distinguishing a cross-border construction contract from the related private law agreements. Based on the results of the legal doctrine and arbitration practice study the author identifies a number of new features.The most important aspects disclosed by the author in the paper concern the theoretical and practical aspects of determining the content of the characteristics of a cross-border construction contract, distinguishing it from other private law contracts.The author makes a conclusion on the formation of new constitutive features of a cross-border construction contract and the possibility of assigning a cross-border construction contract to a separate, independent type of sui generis contracts.
Análisis territorial de la problemática ambiental urbana: el caso del municipio de Facatativá, Cundinamarca, Colombia (1980-2010)
Authors: Hernández Garzón Michelle 
Published: March 2019

La situación ambiental actual del área urbana del municipio de Facatativá es la respuesta a los acontecimientos históricos que se han venido presentando frente a procesos de territorialización, expresados en los fenómenos de urbanización e industrialización. Con el fin de comprender los problemas ambientales en el área urbana de este municipio a partir de su análisis territorial, se determinó desde un enfoque geohistórico, geopolítico y ambiental la configuración territorial urbana entre 1980 y 2010. Se observó que en Facatatitvá se han venido presentando complejos problemas ambientales que repercuten en el reconocimiento del valor del medio ambiente y los recursos naturales, en la calidad de vida y en la sostenibilidad ambiental. En este sentido, la gestión ambiental territorial se convierte en la estrategia que brinda las pautas para la planificación del territorio, propiciando la igualdad, la equidad y su desarrollo sostenible.
Pendidikan Politik melalui Pembelajaran Pendidikan Kewarganegaraan untuk Meningkatkan Kesadaran Politik Siswa
Authors: Mulyadi Yohanes Berkhmas , Anyan Anyan 
Published: March 2019

Abstract.This study aims to describe political education through learning civic education to increase the political awareness of students of Kelam Permai 1 High School, Sintang District. This type of research is descriptive, with a qualitative approach. Research subjects were determined by purposive sampling technique. The subject of this study consisted of the Principal, Classroom Teacher, PKn Subject Teacher, Tutor OSIS Teacher, OSIS Chairman and member of Pramuka. Data collection in this study was carried out by observation, indepth interviews and documentation. Data analysis techniques were carried out by data reduction, categorization, display / presentation, and conclusion. The results of this study indicate that to increase students' political awareness, political education is needed through PKn learning. The form of political education through Civics learning in the classroom is role playing, discussion, learning various sources. The benefits of this research are the increased political awareness of students expressed in attitude, good deeds, critical and responsible in carrying out school activities. Keywords: Political education, Student learning, Student political awareness

Abstrak
Penelitian ini bertujuan mendeskripsikan pendidikan politik melalui pembelajaran pendidikan kewarganegaraan untuk meningkatkan kesadaran politik siswa SMA Negeri 1 Kelam Permai, Kabupaten Sintang.Jenis penelitian ini adalah deskriptif, dengan pendekatan kualitatif. Subjek penelitian ditentukan dengan teknik purposive sampling. Subjek penelitian ini terdiri dari Kepala Sekolah, Guru Wali Kelas, Guru Mata Pelajaran PKn,Pembina OSIS, Ketua OSIS dan anggota Pramuka. Pengumpulan data dalam penelitian ini dilakukan dengan observasi, wawancara mendalam dan dokumentasi.Teknik analisis data dilakukan dengan reduksi data, kategorisasi, display/penyajian, dan pengambilan kesimpulan. Hasil penelitian ini menunjukkan bahwa untuk meningkatkan kesadaran politik siswa, dibutuhkan pendidikan politik melalui pembelajaran PKn. Bentuk pendidikan politik melalui pembelajaran PKn di kelas adalah bermain peran, diskusi, pembelajaran berbagai sumber.Manfaat penelitian ini adalah meningkatnya kesadaran politik siswa yang terekspresi dalam sikap, perbuatan yang baik, kritis dan bertanggungjawab dalam melaksanakan kegiatan sekolah.
Kata Kunci: Pendidikan politik, Pembelajaran PKn, Kesadaran Politik
Penerapan Model Scramble untuk Meningkatkan Motivasi Belajar pada Mata Pelajaran Pendidikan Kewarganegaraan (PKn)
Authors: Tuku Prodensia , Hermuttaqien Bhakti Prima Findiga , Ladamay Iskandar 
Published: March 2019

Tujuan penelitian ini untuk mengatasi kurangnya motivasi belajar siswa pada mata pelajaran PKn melalui penerapan model Scramble. Dengan menggunakan metode penelitian kuantitatif eksperimen, sampel yang digunakan dalam penelitian ini ada dua yaitu sampel kelas eksperimen dan sampel kelas kontrol, pemilihan kedua sampel tersebut untuk melihat perbandingan peningkatan motivasi belajar pada mata pelajaran PKn yang di peroleh dari kedua kelas sampel tersebut. Teknik pengumpulan data yang digunakan yaitu dokumentasi, wawancara dan pembagian angket. Dari hasil penelitian yang diuji dengan menggunakan bantuan aplikasi SPSS 22,0 versi windows dan rumus kriteria pengingkatan motivasi belajar menunjukan hasil sebagai berikut, pada kelas eksperimen dengan jumlah responden 32 orang mendapatkan prosentasi peningkatan motivasi belajar pada mata pelajaran PKn adalah 93,5% yang diperoleh dari hasil tes setelah mendapat perlakuan model scramble. Sedangkan prosentasi yang diperoleh pada kelas kontrol setelah belajar dengan menggunakan model konvensional dengan jumlah responden 32 orang memperoleh prosentasi 65,3%. Kesimpulan dari penelitian ini adalah penerapan model scramble pada mata pelajaran PKn dapat meningkatkan motivasi belajar siswa.
Las ideas políticas de Morelos
Authors: Valero Silva José 
Published: March 2019

José Valero Silva analiza el pensamiento de Morelos y afirma que, con ello, pretende enlazar los ideales del caudillo sobre la independencia de México con las corrientes políticas que lo influyeron. Asegura que la obra legislativa de Morelos le confirió un papel de estadista que, junto con su quehacer militar, lo colocó como el héroe máximo de la Independencia. Anexa el documento <em>Sentimientos de la nación </em>o <em>23 puntos dados por Morelos para la Constitución</em>.
ANALYSIS OF IMMUNOHISTOCHEMICAL EXPRESSION OF P16INK4a IN NEOPLASTIC SQUAMOUS CELL LESIONS OF CERVIX
Authors: Mohan Dr. K.R. , Sasikala Dr. S. , Ravi Dr. S. , Sagunthala, Dr. P. , Sathish Kumar, Dr. I.Vijay 
Published: March 2019

Introduction: Cervical cancer is caused by persistent infection by high risk Human papilloma virus (HPV).Increasing expression of HPV viral oncogenes might be reflected by increased expression of p16. Hence immunohistochemical detection of p16INK4a is an easy and cost effective method than molecular detection of HPV.
Aims: The purpose of this study were to evaluate the results of expression of p16INK4a in neoplastic squamous cell lesions of cervix in order to assess the association of HPV infection in those lesions and to study the pattern of expression of p16 and also to compare p16 expression in various histological types of cervical neoplastic squamous cell lesions by immunohistochemistry.
Methods: Immunohistochemical analysis of p16 expression was performed on 26 paraffin embedded tissue samples, obtained from cervical biopsy including 2 early invasive squamous cell carcinoma (SCC), 6 large cell keratinizing SCC, 16 large cell non- keratinizing SCC and 2 cases small cell non-keratinizing SCC by using commercially available mouse monoclonal antibody to p16 (clone G175 – 405). Two parameters were evaluated in p16 expression: Percentage of p16 positive cells and reaction intensity of p16 immunostaining. The p16 expression was graded as negative; Grade 1, 2, 3 and its reaction intensity was graded as negative, weak, moderate and strong.
Results: In the present study out of 26 cases, the incidence of large cell non- keratinizing SCC constituted majority of the neoplastic lesions of cervix (61.5%). Most of the SCC (96.15%) showed grade 3 scoring for p16 positivity except one case which showed grade 2 scoring. Majority of SCC cases (96%) showed strong reaction intensity for p16 immunostaining.
Conclusion: In this study of 26 neoplastic sqaumous cell lesions, all patterns of cervical neoplasia showed p16 positivity. P16 may be useful as an adjunct in histological sections to detect HPV in those lesions.
Telmisartan Quality Control by Validation of UV-Spectrophotometric Method
Authors: Tsvetkova Dobrina , Obreshkova Danka , Ivanova Stefka , Yankov Vladimir , Atanasov Peter , Hadjieva Bozhidarka 
Published: March 2019

The aim of current study was to validate spectrophotometric method with UV-detection for identification and determination of Telmisartan in 99.8 % ethanol in respect of analytical parameters: selectivity, linearity, limit of detection (LOD), limit of quantification (LOQ), accuracy and precision (repeatability). For Telmisartan in 99.8 % еthanol at λ max = 298 nm for A1%1cm and ε the obtained results for А > 0.2 and А < 0.2 are:
1) А > 0.2: at 3.10–6 g/ml ÷ 1.25.10–5 g/ml; A1%1cm: 725 ÷ 823; ε: 37347 ÷ 423352) А < 0.2: at 2.5.10–7 g/ml ÷ 1.10–6 g/ml; A1%1cm: 1201 ÷ 1567; ε: 61816 ÷ 80651
Analytical parameter accuracy is represented by the degree of recovery, which in the corresponding confidence possibility suit the confidence interval: R СТ60: 100.31 % ÷ 102.05 %; R СТ80: 99.22 % ÷ 103.18 %; R СТ100 : 93.58 % ÷ 101.9 %. For precision is proved that all results for the quantities correspond to the relevant confidence interval: СТ60: 60.31 mg ÷ 60.77 mg; СТ80: 79.82 mg ÷ 82.18 mg; СТ100: 94.22 mg ÷ 101.58 mg.
Drug Delirium Scale (DDS): A Tool to Evaluate Drugs as a Risk Factor for Delirium
Authors: Viet-Quoc Nguyen Patrick , Lucie Pelletier , Isabelle Payot , Judith Latour 
Published: March 2019

Objectives: To design the Drug Delirium Scale (DDS), an evaluation tool to assess the drug burden in delirium in the elderly population.
Design: We proceeded with a systematic literature review through database and grey literature. The records were examined by two independent reviewers using the inclusion and exclusion criteria. Data from the selected studies was extracted and a summary chart was written for each drug. Drugs in anticholinergic drug scales, Beers and STOPP criteria for anticholinergic of cognitive impairment effects were also included for evaluation. These summaries were submitted to the geriatric expert panel composed of two geriatric physicians and two geriatric pharmacists. The panel chose each drug included in the DDS list and their rank.
Results: 981 records were identified and 149 met inclusion criteria. The expert panel evaluated 265 drugs and selected 96 drugs for the DDS scale. The mean interrater reliability score was of 0,634 [CI: 0,441; 0,791].
Conclusion: The Delirium Drug Scale (DDS) is the first evaluation tool to assess the risk of delirium derived from drugs used in the elderly population. It was designed using a sound methodological process. The DDS must now be tested in the geriatric population to validate its predictive value for delirium.
Otorhinolaryngology, Head and Neck Surgery Services in Khartoum State in Sudan 2015
Authors: Malik Dr. Malik Ibrahim , Omer Ahmed Dr. Sharfi Abdelgadir , Abdulrahim Dr. Muna Ahmed 
Published: March 2019

Background: In Khartoum state, formal health services are heavily centralized. This is reflected by a specialist services coverage that is double the national ratio in Sudan, as is the case for other health services and cadres.
Objectives: The aim of this study to establishment a database for ENT, audiology and speech therapy services in Khartoum state.
Methods: This is descriptive, cross-sectional study hospital based. Include all Hospitals that provide otorhinolaryngological, head and neck surgery services within Khartoum state.
Results: Total numbers of hospitals included in this study were 16 hospitals and departments providing otorhinolaryngological services in Khartoum state. General hospitals that contain ENT departments were 13 hospitals (81.25%) and hospitals that specialized for otorhinolaryngological services were three hospitals (18.75%).
Conclusion: Otorhinolaryngological hospitals are distributed within Khartoum state with inequality to proportion of populations within provinces, also there is great deficiency on audiology and speech therapy services with variable distribution.