bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing the Effect of Different Hearing Aid Fitting Methods in Bimodal Cochlear Implant Users
Authors: Vroegop Jantien L. , Dingemanse J. Gertjan , van der Schroeff Marc P. , Goedegebure André 
Published: November 2018

Purpose
The aim of the study was to investigate the effect of 3 hearing aid fitting procedures on provided gain of the hearing aid in bimodal cochlear implant users and their effect on bimodal benefit.

Method
This prospective study measured hearing aid gain and auditory performance in a cross-over design in which 3 hearing aid fitting methods were compared. Hearing aid fitting methods differed in initial gain prescription rule (NAL-NL2 and Audiogram+) and loudness balancing method (broadband vs. narrowband loudness balancing). Auditory functioning was evaluated by a speech-in-quiet test, a speech-in-noise test, and a sound localization test. Fourteen postlingually deafened adult bimodal cochlear implant users participated in the study.

Results
No differences in provided gain and in bimodal performance were found for the different hearing aid fittings. For all hearing aid fittings, a bimodal benefit was found for speech in noise and sound localization.

Conclusion
Our results confirm that cochlear implant users with residual hearing in the contralateral ear substantially benefit from bimodal stimulation. However, on average, no differences were found between different types of fitting methods, varying in prescription rule and loudness balancing method.
Predictors of Vocabulary Outcomes in Children Who Are Deaf or Hard of Hearing From Spanish-Speaking Families
Authors: de Diego-Lázaro Beatriz , Restrepo María Adelaida , Sedey Allison Lee , Yoshinaga-Itano Christine 
Published: November 2018

Purpose
The goal of this study was to identify predictors of expressive vocabulary in young Spanish-speaking children who are deaf or hard of hearing living in the United States.

Method

This cross-sectional study considered 53 children with bilateral hearing loss between 8 and 34 months of age (
M =
24,
SD =
6.9). Demographic variables, variables related to the hearing loss, and intervention variables were included in a hierarchical regression analysis to predict expressive vocabulary quotients from the MacArthur Inventario del Desarrollo de Habilidades Comunicativas (Communicative Development Inventories;
Jackson-Maldonado et al., 2003
).

Results
Chronological age, degree of hearing loss, functional hearing ability ratings, age of enrollment in early intervention, and the interaction between chronological age and age of intervention accounted for 61.5% of the vocabulary variance. Children who received intervention by 6 months of age achieved significantly higher vocabulary outcomes than children who started intervention later.

Conclusion
The children's mean vocabulary outcomes were below average when compared with hearing peers. This was especially true for older children, children with moderately-severe-to-profound hearing loss, and children who began intervention after 6 months of age. This delay in vocabulary outcomes has the potential to interfere with future reading and academic outcomes.
Energy‐efficient leakage‐based oscillator with stacked structure for nW harvesters
Authors: Jang E. , Lee H. , Lee Y. 
Published: November 2018

An ultra‐low‐power oscillator with 0.24 pJ/cycle energy efficiency is presented, suitable for nanowatt‐level energy harvesters. The sub‐pJ/cycle energy efficiency is comparable with the lowest energy per cycle costs of prior arts and is achieved by minimising short‐circuit current with a leakage‐based delay cell and minimising dynamic power consumption with a capacitively coupled stacked structure. The proposed oscillator is fabricated in 180 nm CMOS process. Under 2.2 V supply voltage, the energy per cycle is 0.24 pJ/cycle over a frequency range of 18.2–226 kHz.
The HARPS search for southern extra-solar planets
Authors: Udry S. , Dumusque X. , Lovis C. , Ségransan D. , Diaz R. F. , Benz W. , Bouchy F. , Coffinet A. , Lo Curto G. , Mayor M. , Mordasini C. , Motalebi F. , Pepe F. , Queloz D. , Santos N. C. , Wyttenbach A. , Alonso R. , Collier Cameron A. , Deleuil M. , Figueira P. , Gillon M. , Moutou C. , Pollacco D. , Pompei E. 
Published: November 2018

Context. We present radial-velocity measurements of eight stars observed with the HARPS Echelle spectrograph mounted on the 3.6-m telescope in La Silla (ESO, Chile). Data span more than ten years and highlight the long-term stability of the instrument.
Aims. We search for potential planets orbiting HD 20003, HD 20781, HD 21693, HD 31527, HD 45184, HD 51608, HD 134060 and HD 136352 to increase the number of known planetary systems and thus better constrain exoplanet statistics.
Methods. After a preliminary phase looking for signals using generalized Lomb-Scargle periodograms, we perform a careful analysis of all signals to separate bona-fide planets from signals induced by stellar activity and instrumental systematics. We finally secure the detection of all planets using the efficient MCMC available on the Data and Analysis Center for Exoplanets (DACE web-platform), using model comparison whenever necessary.
Results. In total, we report the detection of twenty new super-Earth to Neptune-mass planets, with minimum masses ranging from 2 to 30 MEarth and periods ranging from 3 to 1300 days, in multiple systems with two to four planets. Adding CORALIE and HARPS measurements of HD20782 to the already published data, we also improve the characterization of the extremely eccentric Jupiter orbiting this visual companion of HD 20781.
Sexual Function of Women with Infertility
Authors: Salomão Priscilla Bianchini , Navarro Paula Andrea , Romão Adriana Peterson Mariano Salata , Lerri Maria Rita , Lara Lúcia Alves da Silva 
Published: November 2018

Objective To assess the sexual function, anxiety, and depression of infertile women relative to a control group.
Methods Infertile women (infertile group, IG) of reproductive age were invited to participate in this controlled study. A control group (CG) of women was recruited from the general population of the same city. Sexual function was assessed by the Female Sexual Function Index (FSFI), and anxiety and depression were measured by the Hospital Anxiety and Depression Scale (HADS).
Results A total of 280 women participated in the present study, 140 in the IG and 140 in the CG. The analysis of the FSFI scores showed that 47 women (33.57%) in the IG and 49 women (35%) in the CG had sexual dysfunction (FSFI ≤ 26.55; p = 0.90). Women with anxiety or depression had a greater risk of sexual dysfunction, and sexual dysfunction increased the risk of anxiety and depression. Married women had a lower risk of depression than single women who were living with their partners.
Conclusion Infertile women had no increased risk of sexual dysfunction relative to controls. Anxiety and depression increased the risk of sexual dysfunction in the studied population.
Rare Branching Pattern of the Subscapular Artery
Authors: Tverskoi Alexey Vladimirovich , Morozov Vitaly Nikolaevich , Petrichko Svetlana Aleksandrovna , Pushkarskiy Vitaly Vladimirovich , Parichuk Aleksandr Sergeevich 
Published: November 2018

AbstractVariations of the axillary artery and its branches are quite common. Some variations are clinically significant and having knowledge of them can be useful for the prevention of diagnostic errors during surgical interventions in the axillary fossa. Classically, the third part of the axillary artery presents three branches—the subscapular, the anterior, and the posterior circumflex humeral arteries. The subscapular artery is divided into the circumflex scapular and the thoracodorsal arteries. Our work presents a previously undescribed branching pattern of the right subscapular artery. It branched into the thoracodorsal, the circumflex scapular, the profunda brachii, and the anterior and posterior circumflex humeral arteries. The profunda brachii artery was 0.4 cm in diameter and ran inferiorly to the humeromuscular canal. No branches of the profunda brachii artery were found in the superior part of the arm before entering the humeromuscular canal. No variations in the other parts of the right axillary artery and of the left axillary artery were discovered. The described branching pattern of the subscapular artery can be important and essential for surgeons and radiologists.
Anatomic Variations of Mandibular Condyles in Brazilian Specimens
Authors: Fonseca Roberta , Schetino Luana , da Silva Janice , Almeida-Leite Camila 
Published: November 2018

Objective To describe the morphological characteristics and asymmetries between the left and right mandibular condyles in Brazilian cadaveric specimens.
Material and Methods Thirty-two jaws were placed on a rigid support for image acquisition of the frontal and lateral views. The shapes of the mandibular condyles were classified, and measurements of the distance between the anatomical landmarks in the lateral and frontal views were performed.
Results Mandibular length and width were not different between the right and left sides. Regarding the shapes of the mandibular condyles, the rounded type was the most frequent, followed by marked medial slope; flattened; overhanging lateral and medial slopes; downward flattening of both slopes and their merger in a single, extensive surface; and deformity and marked lateral slope with flaring and flattening. Asymmetry between the left and right mandibular condyles was present in 40% of the specimens.
Conclusion The anatomy of mandibular condyles varies greatly, and this knowledge can avoid misdiagnosis by image examination of the anatomic variations.
Morphology of the Cervical Lymph Nodes of Agouti (Dasyprocta prymnolopha, Wagler, 1831)
Authors: de Carvalho Paulo , Guerra Sérgio , Rizzo Márcia , da Silva Andrezza , Cavalcante Maria , Conde Júnior Airton 
Published: November 2018

AbstractIn the scientific literature, works related to the morphology and histology of agoutis, Dasyprocta prymnolopha, Wagler, 1831, approach several organs and systems. However, none referenced the lymph nodes of this animal. The objectives of the present study were to perform morphological and histological analyses, under optical microscopy, of the cranial and cervical lymph nodes of agoutis, comparing them with the typical lymph nodes of already documented animal species. In the present work, four animals were used, respecting all the ethical and legal aspects, followed by the development of methodologies related to the morphology and histology in question. The results obtained did not show significant morphological and histological differences between the cranial and cervical lymph nodes of agoutis when compared with typical lymph nodes of the animal kingdom.
Evaluación de la vascularización del colgajo interoseo posterior mediante angiografía intraoperatoria con indocianina verde
Authors: Gutierrez Diego Fernando , Hartwig Denisse , Giachero Virginia 
Published: November 2018

ResumenLa angiografía con indocianina verde es una herramienta que permite, entre otros usos, valorar la vascularización de los colgajos en tiempo real. Presentamos el caso de un paciente con una herida en dorso de mano por extravasación de citostáticos, en el que se plantea una reconstrucción con un colgajo interóseo posterior. La ecografía Doppler preoperatoria no logró identificar la arteria interósea posterior a partir del tercio medio de antebrazo, por lo que realizamos una angiografía con indocianina verde intraoperatoria, que permitió identificar una hipoplasia de la arteria interósea posterior y comprobar la viabilidad del colgajo.
Components of attack response inhibition in fencing: Components of attack response inhibition in fencing
Authors: Gutiérrez‐Davila Marcos , Rojas F. Javier , Gutiérrez‐Cruz Carmen , Navarro Enrique 
Published: November 2018

AbstractApplying the Go/No‐Go paradigm to fencing, we investigated the relationship between the moment at which the No‐Go signal appeared after a movement had been initiated and the time required by fencers to suppress the motor execution of a step‐lunge. Secondarily, we determined a time threshold from which movement inhibition results in an error. The No‐Go stimulus was represented by a real attack movement. 18 elite fencers and a fencing master were included in the study. Four force plates measured the horizontal components of the fencer's and master's reaction forces, which were used to calculate the time components of the attack and the response inhibition process. Also, the velocity and displacement of the master's and fencer's respective centres of mass were estimated using inverse dynamics. In all cases, cognitive inhibition processes were completed after the onset of movement. Movement time was calculated using four time components (muscle activation, muscle deactivation, transition and braking time). The results obtained revealed that cognitive processes were not significantly affected by the timing of the appearance of the No‐Go signal. In contrast, movement time and its time components tended to decrease when the time delay between the No‐Go stimulus and the onset of the fencer's movement increased. In conclusion, any attempt to withhold an attack movement when it has already started leads to an error that increases the risk of being hit by the opponent, especially when attack is inhibited within 150 ms after the movement has started.
Belousov–Zhabotinsky reaction in liquid marbles
Authors: Fullarton Claire , Draper Thomas C , Phillips Neil , de Lacy Costello Ben P J , Adamatzky Andrew 
Published: November 2018

Abstract
In Belousov–Zhabotinsky (BZ) type reactions, chemical oxidation waves can
be exploited to produce reaction-diffusion processors. This paper reports on a
new method of encapsulating BZ solution in a powder coating of either
polyethylene (PE) or polytetrafluoroethylene (PTFE), to produce BZ liquid
marbles (LMs). BZ LMs have solid–liquid interfaces compared to previously
reported encapsulation systems, BZ emulsions and BZ vesicles. Oscillation
studies on individual LMs established PE-coated LMs were easier to prepare and
more robust than PTFE-coated LMs. Therefore, this coating was used to study BZ
LMs positioned in ordered and disordered arrays. Sporadic transfer of excitation
waves was observed between LMs in close proximity to each other. These results
lay the foundations for future studies on information transmission and
processing arrays of BZ LMs. Future work aims to elucidate the effect of other
physical stimuli on the dynamics of chemical excitation waves within these
systems.
Set of approaches based on 3D structure and position specific-scoring matrix for predicting DNA-binding proteins
Authors: Nanni Loris , Brahnam Sheryl 
Published: November 2018

Abstract

Motivation
Because DNA-binding proteins (DNA-BPs) play a vital role in all aspects of genetic activity, the development of reliable and efficient systems for automatic DNA-BP classification is becoming a crucial proteomic technology. Key to this technology is the discovery of powerful protein representations and feature extraction methods. The goal of this article is to develop experimentally a system for automatic DNA-BP classification by comparing and combining different descriptors taken from different types of protein representations.

Results
The descriptors we evaluate include those starting from the position-specific scoring matrix (PSSM) of proteins, those derived from the amino-acid sequence (AAS), various matrix representations of proteins and features taken from the three-dimensional tertiary structure of proteins. We also introduce some new variants of protein descriptors. Each descriptor is used to train a separate support vector machine (SVM), and results are combined by sum rule. Our final system obtains state-or-the-art results on three benchmark DNA-BP datasets.

Availability and implementation
The MATLAB code for replicating the experiments presented in this paper is available at https://github.com/LorisNanni.
gwasurvivr: an R package for genome-wide survival analysis
Authors: Rizvi Abbas A , Karaesmen Ezgi , Morgan Martin , Preus Leah , Wang Junke , Sovic Michael , Hahn Theresa , Sucheston-Campbell Lara E 
Published: November 2018

AbstractSummaryTo address the limited software options for performing survival analyses with millions of SNPs, we developed gwasurvivr, an R/Bioconductor package with a simple interface for conducting genome-wide survival analyses using VCF (outputted from Michigan or Sanger imputation servers), IMPUTE2 or PLINK files. To decrease the number of iterations needed for convergence when optimizing the parameter estimates in the Cox model, we modified the R package survival; covariates in the model are first fit without the SNP, and those parameter estimates are used as initial points. We benchmarked gwasurvivr with other software capable of conducting genome-wide survival analysis (genipe, SurvivalGWAS_SV and GWASTools). gwasurvivr is significantly faster and shows better scalability as sample size, number of SNPs and number of covariates increases.Availability and implementationgwasurvivr, including source code, documentation and vignette are available at: http://bioconductor.org/packages/gwasurvivr.Supplementary informationSupplementary data are available at Bioinformatics online.
Structure and functional interactions of INO80 actin/Arp module
Authors: Zhang Xuan , Wang Xuejuan , Zhang Zhihui , Cai Gang 
Published: November 2018

AbstractThe presence and functions of nuclear actin have been controversial due to the lack of molecular mechanisms. Nuclear actin and actin-related proteins (Arps) are subunits of several chromatin remodelers, including the evolutionarily conserved INO80 chromatin-remodeling complex. Here, we present an improved cryo-EM structure of the yeast INO80 complex and the first 3D reconstruction of the INO80 actin/Arp module. The modular and subunit architecture is defined using a combination of subunit deletion analysis and published crosslinking-mass spectrometry. The functional interactions of the INO80 actin/Arp module with a nucleosome is 3D EM reconstructed in two different binding states. Nucleosomes initially bind to the Arp8 subunit and the substantial conformational changes maximize nucleosome contacts of the actin/Arp module, which could promote the bound nucleosome to be engaged onto the INO80 ATPase domain. Our findings suggest that the conserved nuclear actin/Arp module acts a conformational switch of the INO80 for nucleosome binding.
Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient
Authors: Jent Philipp , Trippel Mafalda , Frey Manuel , Pöllinger Alexander , Berezowska Sabina , Langer Rupert , Furrer Hansjakob , Béguelin Charles 
Published: November 2018

Abstract
We report the case of a young patient treated with rituximab-containing chemotherapy who was infected with measles despite previous vaccination. Treatment with vitamin A, ribavirin, and immunoglobulins was started; nevertheless he developed severe pneumonitis and deceased. Broad vaccination coverage is crucial in protecting vulnerable subjects.
How to treat Sjögren’s syndrome
Authors: Price Elizabeth J , Baer Alan N 
Published: November 2018

AbstractSS is a chronic, autoimmune disease of unknown aetiology for which there is no known curative treatment. Although dryness of the eyes and mouth are the classically described features, patients often experience drying of other mucosal surfaces and systemic manifestations, including fatigue and arthralgia. There is an association with other autoimmune diseases, especially thyroid disease, coeliac disease and primary biliary cholangitis. Systemic features may affect up to 70% and include inflammatory arthritis, skin involvement, haematological abnormalities, neuropathies, interstitial lung disease and a 5–10% lifetime risk of B cell lymphoma. Treatment should aim to empower patients to manage their condition; conserve, replace and stimulate secretions; prevent damage; and suppress underlying systemic disease activity.
Effect of particle size of a mash concentrate on behavior, digestibility, and macroscopic and microscopic integrity of the digestive tract in Holstein bulls fed intensively1
Authors: Devant Maria , Solé Anna , Quintana Bruna , Pérez Armando , Ribó Josep , Bach Alex 
Published: November 2018

Abstract
Twenty-four individually housed Holstein bulls (456 ± 6.9 kg of body weight and 292 ± 1.4 d of age) were enrolled in a complete randomized experiment involving four dietary treatments to evaluate the potential effect of mash particle size of diets in finishing beef diets on behavior, digestibility, and macro- and microscopic changes of the digestive tract. The four treatments were all ingredients sieved at 2 mm (HM2), all ingredients sieved at 3 mm (HM3), all ingredients, but corn, sieved at 2 mm and corn at 10 mm (HM210), and all ingredients, but corn, sieved a 3 mm and corn at 10 mm (HM310). For the HM210 and HM310 mashes, corn ground at 10 mm was mixed with the remaining concentrate ingredients ground at 2 or 3 mm, respectively. Concentrate (36% corn, 19% barley, 15% corn gluten feed, 8.4% wheat; 14% crude protein, 3.28 Mcal of ME/kg) consumption was recorded daily and straw consumption weekly. To register behavior, animals were filmed for 24 h on a weekly basis. At day 49 of study nutrient digestibility was estimated. Bulls were slaughtered after 56 d of exposure to treatments. Digestive tract and hepatic lesions were recorded, and tissue samples from the digestive tract collected. Geometric mean particle size was 0.61 ± 0.041, 0.76 ± 0.041, 0.62 ± 0.041, 0.73 ± 0.041 mm, and percentage of particles between 0.5 and 1 mm were 68 ± 2.9, 46 ± 1.7, 46 ± 5.0, and 39 ± 3.3 g/100 g for HM2, HM210, HM3, and HM310, respectively. Performance, total tract digestibility, or digestive tract integrity did not differ when ingredients were ground at 2 or 3 mm. Grinding corn with a hammer mill sieve size of 10 mm reduced feed efficiency and decreased total tract apparent dry matter, and organic matter digestibility compared with treatments from which all ingredients were ground at 2 or 3 mm. Straw intake was greatest and starch digestibility was least in the HM210 treatment. Last, only minor differences among treatments in rumen wall color, rumen papillae fusion, and histological conformation were observed. In summary, to improve feed efficiency, grinding corn at 10 mm is not recommended. In the present study, grinding procedure did not have a great effect on behavior and/or digestive tract health; however, under commercial conditions (group housing), grinding procedures that cause small mean particle sizes or particle size heterogeneity may increase the risk to suffer digestive tract lesions.