bluuebunny/crossref_metadata_2025_split huggingface dataset:
Editorial
Authors: Thomas Joby 
Published: August 2019

Atna-Journal of Tourism Studies (AJTS) now in the ninth year of publication has become a major platform for the publication of high quality articles on research and learning in tourism. AJTS has continued to make serious efforts to understand the varied aspects and issues related to the study of tourism. Scholars have strengthened this publication through high quality articles. The efforts of reviewers have helped to enhnce the quality of the articles submitted for publication. We are very grateful to all the authors and reviewers for helping AJTS to become known to the travel and tourism community in our country. The articles in the current issue range across such diverse disciplines as the use of new media in travel decisions, Geographical Information System (GIS) for tourism administration, destination performance evaluation, wine tourism and a new perspective on sustainability in the hospitality sector.
ВЛИЯНИЕ ПОЛИМОРФНОГО МАРКЕРА RS3846664 ГЕНА ГМГ-КОА-РЕДУКТАЗЫ НА МЕТАБОЛИЗМ ОБЩЕГО ХОЛЕСТЕРИНА СЫВОРОТКИ КРОВИ У ЖЕНЩИН
Authors: Osedko Olga Yakovlevna , Osedko Aleksey Vladimirovich , Kotlovskiy Michael Yurevich , Dygai Alexander Mikhaylovich 
Published: August 2019

Цель данного исследования заключалась в установлении наличия ассоциаций полиморфного маркера rs3846663 гена ГМГ-КоА-редуктазы с общим холестерином как в группе условно здоровых лиц, без разделения по гендерному признаку, так и отдельно в группе женщин и мужчин. Исследование проводилось в группе условно здоровых лиц в количестве 173 человек (105 женщин, 68 мужчины). Для идентификации одноточечного нуклеотидного полиморфизма использовали реакцию минисеквенирования с последующей детекцией продуктов реакции с использованием метода времяпролетной масс-спектрометрии с матрично-активированной лазерной десорбцией/ионизацией.В проведённом исследовании у носителей патологических генотипов (СТ и ТТ) полиморфного маркера rs3846663 гена ГМГ-КоА-редуктазы содержание общего холестерина было статистически значимо выше, чем у лиц с нормальным генотипом СС. Также было установлено, что носительство генотипов СТ и ТТ увеличивает вероятность повышенного содержания общего холестерина относительно целевой нормы. У женщин, носителей генотипов СТ и ТТ полиморфного маркера rs3846663 гена ГМГ-КоА-редуктазы, концентрация общего холестерина была статистически значимо выше. Более того, высокой также являлась вероятность повышенного содержания общего холестерина относительно целевой нормы. У здоровых мужчин наличие патологического аллеля Т не оказало влияние на содержание общего холестерина.
КОМПРЕССИОННАЯ ТЕХНОЛОГИЯ ИЗГОТОВЛЕНИЯ СЪЕМНЫХ АКРИЛОВЫХ ЗУБНЫХ ПРОТЕЗОВ ПОСРЕДСТВОМ ПРИМЕНЕНИЯ КЮВЕТЫ ДВОЙНОГО ВИНТОВОГО ДОЖАТИЯ
Authors: Rаdkeviсh Аndrey Аnаtоleviсh , Сhizhоv Yuriy Vаsilyeviсh , Musсаdine Lev Evgenieviсh , Kаzаntsevа Tаmаrа Vlаdimirоvnа 
Published: August 2019

Цель: разработка метода изготовления съёмных зубных протезов компрессионным способом в латунных классических кюветах с получением разъемной пресс формы (штамп+контрштамп) без существенного удорожания себестоимости конечного продукта с применением кювет двойного винтового дожатия.Материалы и методы. Описана разработанная конструкция кюветы двойного винтового дожатия, технология изготовления съемных пластмассовых зубных протезов с ее использованием. Содержание остаточного мономера в стоматологической пластмассе осуществляли методом экстракции. Использовали образцы стоматологических базисных акриловых пластмасс: протакрил, вертекс, бесцветная, этакрил и фторакс в виде брусков. Образцы получали серийно в кювете двойного винтового дожатия с одинаковыми условиями полимеризации. Методом спектрофотометрии определяли количество остаточного мономера через 5, 10, 17, 19, 22 суток в каждой пробе. Пористость вышеуказанных образцов изучали путем электронно-микроскопического сканирования сколотых поверхностей, напыленых платиной в установке вакуумного магнетронного напыления K575XD.Результаты. Установлено, что содержание остаточного количества мономера в образцах, изготовленных с помощью кюветы двойного винтового дожатия, было меньше, в сравнении с традиционными технологиями, в «протакриле» в 10 раз, «вертексе» – в 7 раз, бесцветной пластмассе – в 2 раза, «этакриле» и «фтораксе» – в 4 раза. Пористость основной поверхности для пластмасс «вертекс», «протакрил», «фторакс» и «этакрил» не превышала тысячных долей процента, исключение составила бесцветная пластмасса, имеющая относительно высокую пористость – 3,9%.Заключение. Предложенная кювета двойного винтового дожатия позволяет сохранять заданные размеры (вследствие отсутствия грата), значительно уменьшить токсичность и пористость пластмасс и, как следствие, повысить прочностные свойства изготавливаемых протезов.
Service improvement study to improve care for patients who developed a surgical site infection after discharge
Authors: Tyrer Julie 
Published: August 2019

Background: many patients develop surgical site infection (SSI) after they have been discharged from hospital. SSI rate is a quality measure intended to support healthcare providers with useful information to improve service and patient outcomes. Aim: the purpose of the study was to gain some local insight into current practice and to inform and improve clinical practice for patients who develop SSIs after they have been discharged. Method: a quantitative approach was taken, using retrospective data collection and analysis of patient records, of patients reviewed by the tissue viability service after discharge over a 1-year period. Findings: a total of 112 patients were included in the study. Of these, 59 were assessed as having developed an SSI, of whom 39 patients presented after discharge. Most of these patients had shorter inpatient stays and many were under the care of community nurses, but referral to the specialist tissue viability service to seek expert advice was often delayed. Conclusion: the study has highlighted the potential value of post-discharge surveillance in contributing to more accurate SSI rates, and the importance of patients and community nurses being provided with clear, understandable information to ensure patients receive timely and effective management, which could reduce the severity of, and duration of treatment for, SSIs.
Sequential spine-hand radiography for assessing skeletal maturity with low radiation EOS imaging system for bracing treatment recommendation in adolescent idiopathic scoliosis: A feasibility and validity study
Authors: Lau L. C. M. , Hung A. L. H. , Chau W. W. , Hu Z. , Kumar A. , Lam T. P. , Chu W. C. W. , Cheng J. C. Y. 
Published: August 2019

Purpose The EOS-imaging system is increasingly adopted for clinical follow-up in scoliosis with the advantages of simultaneous biplanar imaging of the spine in an erect position. Skeletal maturity assessment using a hand radiograph is an essential adjunct to spinal radiography in scoliosis follow-up. This study aims at testing the feasibility and validity of a newly proposed EOS workflow with sequential spine-hand radiography for skeletal maturity assessment and bracing recommendation. Methods EOS spine-hand radiographs from patients with diagnosis of idiopathic scoliosis, including both sexes and an age range of ten to 14 years, were scored using the Thumb Ossification Composite Index (TOCI), Sanders and Risser methods. Intraclass correlation coefficients (ICCs) were calculated for inter/intraobserver agreement and were tested with Cronbach's alpha values. Results In all, 60 EOS-spine hand radiographs selected from subjects with diagnosis of adolescent idiopathic scoliosis (AIS), including 32 male patients (mean age 11.53 years; 10 to 14) and 28 female patients (mean age 11.50 years; 10 to 13) who underwent sequential spine-hand low dose EOS imaging were generated for analysis. The overall interobserver (ICC = 0.997) and intraobserver agreement (α > 0.9) demonstrated excellent agreement for TOCI staging; ICC > 0.994 for both TOCI and Sanders staging comparing traditional digital versus EOS hand radiography; ICC ≥ 0.841 for agreement on bracing recommendation among TOCI versus the Risser and Sanders system. Conclusion With the proposed new EOS workflow it was feasible to produce high image quality for skeletal maturity assessment with excellent reliability and validity to inform consistent bracing recommendation in AIS. The workflow is applicable for busy daily clinic settings in tertiary scoliosis centres with reduced time cost, improved efficiency and throughput of the radiology department. Level of evidence III
Intake of Dietary Fiber, Fruits, and Vegetables and Risk of Diverticulitis
Authors: Ma Wenjie , Nguyen Long H. , Song Mingyang , Jovani Manol , Liu Po-Hong , Cao Yin , Tam Idy , Wu Kana , Giovannucci Edward L. , Strate Lisa L. , Chan Andrew T. 
Published: August 2019

OBJECTIVES:
Although low fiber intake has been considered a risk factor for diverticulitis, prospective evidence is limited in women despite having a disproportionate burden of disease, with little known about variation in the protective effects according to food sources. We assessed the associations of intakes of fiber and major food sources of fiber including fruits and vegetables with risk of diverticulitis in a large cohort of women.

METHODS:
We followed 50,019 women in the Nurses' Health Study (1990–2014) who were aged 43–70 years and free of diverticulitis, cancer, and inflammatory bowel disease at baseline. Incident diverticulitis was identified through self-report with validity confirmed by review of medical records.

RESULTS:
We documented 4,343 incident cases of diverticulitis, encompassing 1,106,402 person-years of follow-up. Compared with participants in the lowest quintile, the multivariable hazard ratio of diverticulitis in the highest quintile of total fiber intake was 0.86 (95% confidence interval: 0.78–0.95; P-trend = 0.002). Fiber from fruits and cereals, but not vegetables, was associated with a decreased risk of diverticulitis. Furthermore, intake of total whole fruit intake and specific fruits such as apples/pears and prunes were associated with reduced risk of diverticulitis with a multivariable hazard ratio for diverticulitis of 0.95 (0.92–0.98; P-trend < 0.001) for every serving increase of total whole fruit intake per day.

DISCUSSION:
Higher intake of dietary fiber and fiber from different food sources, except for vegetable fiber, are associated with a lower risk of diverticulitis in women. A greater intake of whole fruit is also associated with reduced risk.
Persistent Hiccups Because of Water Intoxication by Colonic Irrigation With Tap Water
Authors: van Weelden Marlon , Edelenbos Esther , de Meij Tim 
Published: August 2019

ABSTRACT
Hyponatremia by colonic irrigation with water is a rare complication, especially in children. We describe a child with chronic constipation who was admitted because of persistent hiccups provoked by severe hyponatremia by water intoxication due to colonic irrigation with tap water. Awareness of complications of colonic irrigation may be crucial for health care providers and parents to rapidly recognize a serious underlying problem.
Gastric Ulcer and Perforation due to Mucormycosis in an Immunocompetent Patient
Authors: Sehmbey Gurbir , Malik Rameez , Kosa Dimas , Srinivasan Indu , Chuang Keng-Yu , Bellapravalu Sharad 
Published: August 2019

ABSTRACT
Mucormycosis is a rare and life-threatening fungal infection that is associated with high mortality in immunocompromised individuals. Although it most commonly affects lungs and paranasal sinuses, cases of invasive mucormycosis of the gastrointestinal tract have also been reported. Gastrointestinal mucormycosis (GIM) is most commonly found in the stomach, colon, and ileum. Etiologies of GIM include ingestion of spores and penetrating abdominal trauma, causing mucocutaneous disruption. We present a case of an immunocompetent man who presented to our hospital after a gunshot wound to the abdomen. His hospital course was complicated with the development of invasive GIM in the form of a large gastric ulcer, which caused gastrointestinal bleeding and eventually perforation.
An Analysis of Increasing the Purity of Ethylene Production in the Ethylene Fractionation Column by the Genetic Algorithm
Authors: Karimi Asadollah , Soltani Hadi , Hasanzadeh Aydin 
Published: August 2019

AbstractDistillation columns are among the most common fractionation systems with numerous applications in petrochemical units. Hence, the optimization of these columns is a large step in reducing energy consumption and increasing process productivity. This study was, therefore, carried out as a case study of the simulation and optimization of the parameters influencing the ethylene production of the ethylene distillation column in an olefin unit. The two defined objective functions in this research were maximum mass flow of ethylene in the upstream flow of the distillation column and the minimum energy consumption in the distillation column. The optimal operating conditions for the independent variables were estimated using the NSGAII algorithm. The sensitivity analysis of the results was, thereafter, carried out and the optimization results introduced tray no. 71 as the most suitable feed location. In addition, the optimal reflux ratio and the optimal feed flow temperature were 5.26 and −18.49 °C, respectively. In this condition, the upstream ethylene flow rate and energy consumption in the unit increased by approximately 0.74 % and 0.9 % as compared to the initial conditions, respectively.
Amour et santé dans leBanquetde Platon : la notion d’harmonie
Authors: Saudelli Lucia 
Published: August 2019

AbstractThe structure as well as the themes of theSymposiumsuggest that Eryximachus’ speech plays a fundamental role in the dialogue. The problem is that what he says in praise of love is far from clear and continues to be a subject of debate. The aim of our article is to re-examine this speech to clarify its meaning and determine its contribution to Plato’s theory of love. First, we will analyse thetextof theSymposium, then we will investigate itsmedicalback-ground, and finally we will evaluate itsphilosophicalimpact. We will argue that Eryximachus’ speech, which draws inspiration from the Hippocratic Collection and the Pre-Socratic thought, is based on the concept of ‘harmony’: a balanced and organised unity of opposites. According to Eryximachus, love – conceived of as harmony – is the key to thehealthand thevirtueof human beings, as well as to the cosmic order and justice. Thereby the specificity of Eryximachus’ speech will become clear: Plato tries to combinescienceandmoralityby proposing, among other things, some considerations onbioethics.
Épictète et la doctrine des indifférents et dutelosd’Ariston à Panétius
Authors: Bénatouïl Thomas 
Published: August 2019

AbstractWhile Epictetus’Diatribaiare not an ethical treatise, but aim chiefly at urging and training pupils to practice philosophy, they can also be used to reconstruct Epictetus’ positions about some of the questions raised within the Stoa after Zeno. This paper focuses on the problem of the contribution of indifferent (external or bodily) things to happiness and of the relationship between virtue and these indifferents. Against scholars claiming that Epictetus shared Aristo of Chios’ heterodox indifferentism, it is shown that Epictetus upholds Chrysippus’ ethical doctrine of thetelosand acknowledges that some indifferents are natural or have ‘value’ (axia) and should not be despised or ignored. In making this point, Epictetus uses the concept of ‘good reasonning’ about value which can be traced back to Diogenes of Seleucia (and Antipater of Tarsus). Moreover, when he describes how we can reach the goal of life through our natural faculties, Epictetus might also borrow Panetius’ explanation of thetelos.
Rivalutare l’Etica Eudemia. A proposito di A. Kenny, The Aristotelian Ethics, II edizione
Authors: Natali Carlo 
Published: August 2019

Abstract
In the paper I discuss three theses defended by A. Kenny: (1) in antiquity up to Aspasius or to Alexander of Aphrodisias the EE was considered the most important version of Aristotle’s ethical discourse; (2) the idea that the common books belonged to the one or to the other treatise; (3) the opposition between the theory of happiness of EN I and X and that of EE II and VIII.
Charting the rise and demise of a phonotactically motivated change in Scots
Authors: Maguire Warren , Alcorn Rhona , Molineaux Benjamin , Kopaczyk Joanna , Karaiskos Vasilios , Los Bettelou 
Published: August 2019

AbstractAlthough Old English [f] and [v] are represented unambiguously in Older Scots orthography by <f> and <v> (or <u>) in initial and morpheme-internal position, in morpheme-final position <f> and <v>/<u> appear to be used interchangeably for both of these Old English sounds. As a result, there is often a mismatch between the spellings and the etymologically expected consonant. This paper explores these spellings using a substantial database of Older Scots texts, which have been grapho-phonologically parsed as part of theFrom Inglis to Scots(FITS) project. Three explanations are explored for this apparent mismatch: (1) it was a spelling-only change; (2) there was a near merger of /f/ and /v/ in Older Scots; (3) final [v] devoiced in (pre-)Older Scots but this has subsequently been reversed. A close analysis of the data suggests that the Old English phonotactic constraint against final voiced fricatives survived into the pre-Literary Scots period, leading to automatic devoicing of any fricative that appeared in word-final position (a version of Hypothesis 3), and this, interacting with final schwa loss, gave rise to the complex patterns of variation we see in the Older Scots data. Thus, the devoicing of [v] in final position was not just a phonetically natural sound change, but also one driven by a pre-existing phonotactic constraint in the language. This paper provides evidence for the active role of phonotactic constraints in the development of sound changes, suggesting that phonotactic constraints are not necessarily at the mercy of the changes which conflict with them, but can be involved in the direction of sound change themselves.
The dignity approach to human rights and the impaired autonomy objection
Authors: Caranti Luigi 
Published: August 2019

Abstract
There is little need to argue for the importance of human rights (HRs) in our world. If one looks at the role they play today, it is hard to deny that their impact has increased beyond anything the drafters of the 1948 Universal Declaration could have hoped or imagined. However, even though human rights today have a far greater impact on politics than in the past, the philosophical reflection that surrounds them has had a less fortunate history. It is doubtful whether we are today in a better position than we were in 1948 to answer any of the philosophical questions surrounding them, including, and perhaps most crucially, the question about their foundation. Why are human rights standards—of whatever sort—that we should adopt, or even just take seriously? The first two parts of this paper summarize my recent work on the above question (Caranti, 2017) and the third takes it a step further. I will 1) show why the main orientations in the contemporary philosophy of human rights all fail to yield a satisfactory foundation, 2) sketch an alternative foundation that exploits Kant’s account of human dignity in a rather critical way; and 3) address one major objection my approach is bound to attract (and in a certain form has already attracted). Since my foundation suggests that we have dignity (and as a consequence human rights) because we are autonomous, that is, capable of moral behavior, some scholars have argued that I am bound to the counterintuitive conclusion that people with a temporary or permanent lack of rational capacity, which would cause a condition of “impaired autonomy,” are not entitled to the protection of human rights. While this objection does nothing but reformulate in the language of human rights an old, classical objection to Kant’s ethics, replying to it requires mobilizing new intellectual resources.
The grammar of rights and the grammar of needs
Authors: Pinzani Alessandro 
Published: August 2019

Abstract
The paper is structured into four parts. Firstly I discuss the connection between the concept of injustice and the idea of human or individual rights. The claim is quite trivial: the language of rights has been and is still used as a strategy to demand correctives against injustice. Since this strategy has negative effects, of which concrete examples are given, I suggest a different grammar be adopted, the grammar of needs, which is what societies adopt in their justificatory discourses anyway. This leads into a consideration of how social criticism could start precisely from such discourses and why, under specific circumstances, the grammar of needs could represent a better strategy for this criticism than the language of rights does.
Topicality and the typology of predicative possession
Authors: Chappell Hilary , Creissels Denis 
Published: August 2019

AbstractRecent accounts on the typology of predicative possession, including those by Stassen, recognise a Topic Possessive type with the possessee coded like the figure in an existential predication, and the possessor coded as a topic that is not subcategorised by the predicate and is not related to any syntactic position in the comment, literally: As for Possessor, there is Possessee. The Asian region is explicitly singled out as being a Topic Possessive area.On the basis of a sample of 71 languages from the four main language families of continental East and Southeast Asia – Sino-Tibetan, Hmong-Mien, Tai-Kadai and Austroasiatic, contrary to these previous accounts of the distribution of the main types of predicative possession in the world’s languages, we argue that this area should rather be considered as showing a particularly high concentration of Have-Possessives, with the additional particularity that the verbs occurring in the Have-Possessive constructions in this linguistic area are polysemous verbs also used for existential predication.After briefly reviewing Stassen’s typology of predicative possession, we discuss his account of the Topic Possessive type and then present five arguments for considering why the possessor NP of the existential/possessive verbyǒu有 in Standard Mandarin Chinese cannot be analysed as invariably occupying the position of a topic, and consequently, that the construction should be reclassified as an instance of the Have-Possessive type. In the final sections, the situation is examined for other Southeast Asian languages showing the same configuration for predicative possession and existential predication as Standard Mandarin, to the extent that data is available.