bluuebunny/crossref_metadata_2025_split huggingface dataset:
MICROVASCULAR INJURY PHENOMENA IN MYOCARDIAL INFARCTION
Authors: Alekseeva Ya. V. , Vyshlov E. V. , Ussov V. Yu. , Markov V. A. 
Published: February 2019

At a time of a wide use of coronary reperfusion for treatment of acute myocardial infarction, the microvascular phenomena significantly affecting the postinfarction state of the myocardium have been discovered. These phenomena include microvascular obstruction with a clinical presentation in the form of the no-reflow phenomenon and intramyocardial hemorrhage that strongly aggravate cardiac damage. The aim of this review was to analyze accumulated data on the prevalence, pathophysiology, diagnostic modalities, and approaches for prevention and treatment of microvascular injury.
DOES THE CORRECTION OF THE ANXIETY-DEPRESSIVE DISORDERS INFLUENCE ON THE PROCESSES OF THE LEFT VENTRICULAR REMODELING IN PATIENTS WITH ACUTE CORONARY SYNDROME?
Authors: Poponina T. M. , Gunderina K. I. , Poponina Yu. S. , Soldatenko M. V. 
Published: February 2019

Aim:to study the dynamic of echocardiographic parameters in patients with acute coronary syndrome associated with anxiety and depressive disorders during the therapy by innovative Russian drug containing release-active antibodies to the brain-specific protein S-100 (Tenoten) in-hospital and during six months of treatment.Material and Methods. 54 patients with acute coronary syndrome associated with anxiety and depressive disorders were randomized into 2 groups: patients of group 1 were administered with anti-anxiety medicament Tenoten, 6 tablets per day in addition to the therapy for acute coronary syndrome; group 2 received placebo. All patients underwent echocardiography at inpatient and outpatient stages six months after randomization.Results. Clinically significant anxiety and subclinical depression were detected in patients of both study groups. The intake of anti-anxiety drug Tenoten for six months contributed to anxiety reduction, myocardial contractility improvement, and a decrease in the left ventricular volume indices. Negative changes were observed in comparison group: a decrease in the left ventricular ejection fraction, increase in volume indices, and decline in the left ventricular relaxation.Conclusion. Administration of Tenoten at a dose of six tablets per day to patients with acute coronary syndrome in combination with affective disorders resulted not only in improvement of a mental status, but it also contributed to suppression of the left ventricular remodeling processes.
FLOOR CONSTRUCTION IN BASEMENTS OF RECONSTRUCTED BUILDINGS ON PEATY SOILS
Authors: Невзоров Александр , Nevzorov Aleksandr , Никитин Андрей , Nikitin Andrey , Саенко Юрий , Saenko Yuriy 
Published: February 2019

A practical way to utilize the underground space of buildings is deepening the basement. Where peat is found under the building basement, floor construction proves to be a challenging engineering problem.
The article describes several basement floor construction methods for building reconstruction on peaty soils in the city of Arkhangelsk. Peaty soils require bored, driven or jacked piles up to 8 m long. Due to continuous peat consolidation, "floating" floors resting on the ground cannot be used. Numerical simulation of piles in PLAXIS 3D software provides load-settlement curves closely correlating with the results of static load tests.
Financial and organizational support for the activities of povet sejmiks of GDL 1756–1757: new sources
Authors: Matsuk A. U. 
Published: February 2019

New sources discovered among the documents of the Grabowski family in the funds of the Jagiellonian Library for the first time in historiography show the financing of sejmik companies within the limits of one noblemen group. From these documents, it becomes clear how the general financial fund was formed including the contributions of various noblemen, and also how it was distributed among them, taking into account the costs for specific povet sejmiks. Also, a circle of noblemen and gentry who were responsible for specific sejmiks becomes known. Moreover, plans about the candidacy for the elections after the Sejm ambassadors and the deputies of the Tribunal of the Grand Duchy of the Lithuania from the Radziwill noblemen group become known. As a result of the analysis of identified sources, it was possible to establish that the expenses of the Radziwill noblemen group at the ambassadorial sejmiks in 1756 amounted to 77400 zloty, and on the gromnichny in 1757– 71600 zloty. The most valuable sejmiks were: Vilensky (from 5000 to 9000 zlotys), Grodnensky (5000 zlotys), Brestsky (5000 zlotys), Oshmyansky, Zhmudsky, Polotsky and Mstislavsky (4000 zlotys). Least of 2,000 zlotys were issued for 11 sejmiks (Lidsky, Vilkomirsky, Braslavsky, Trotsky, Upitsky, Smolensksky, Starodubsky, Slonimsky, Pinsky, Mazyrsky and Rechitsky). In the cases of the Vilensky, Starodubsky, Lidsky and Novogrudksky sejmiks, it was possible to find the registers how the money given to these sejmiks was divided between the local supporters of the Radziwills. It is very difficult to assess the effectiveness of these specific costs. At the Hrodna embassy sejmiks 1756, the supporters of the Family were elected ambassadors, and the Radziwill supporters only managed to make an objection against their election. In fact, all of 5,000 zlotys was spent only on objection. Michal Kazimir Radziwill appreciated such a result highly. As may be supposed his assessment depended on the specific political conjuncture that prevailed at that time almost in all povets.
CONSTRUCTING EARTHQUAKE DISASTER-EXPOSURE LIKELIHOOD INDEX USING SHAPLEY-VALUE REGRESSION APPROACH
Authors: Anisa Rahma , Sartono Bagus , Silvianti Pika , Alamudi Aam , IJSA Indonesian Journal of Statistics and Its Applications 
Published: February 2019

Indonesia is very prone to earthquake disaster because it is located in the Pacific ring of fire. Therefore, a reference level of earthquake disaster exposure likelihood events in Indonesia is needed in order to increase people's awareness about the risks. This study aims to determine the index that describes the risk of possible future earthquake disaster. As initial research, this study is focus on earthquake disasters in Java region, as it has the largest population in Indonesia. Several indicators that are related to the severity of earthquake disaster impact, were used in this study. The weights of each indicators were determined by considering its shapley-value, thus all indicators gave equal contribution to the proposed index. The results showed that shapley-value approach can be utilized to construct index with equal contribution of each indicators. In general, the resulted index had similar pattern with the number of damaged houses in each districts.
OPIOID
Authors: Angkejaya Ony W 
Published: February 2019

Opioid adalah salah satu jenis golongan obat anti nyeri yang dapat berikatan secara spesifik dengan reseptor opioid di tubuh manusia. Aktivasi reseptor opioid dapat memberikan efek analgesik kuat terhadap nyeri yang sedang dirasakan manusia. Golongan obat opioid diekstrak dari tumbuhan papaver somniferum/opium dan obat pertama kali yang diisolir adalah Morfin. Tubuh manusia juga dapat memproduksi opioid endogen secara alami yang nanti juga memberikan efek yang sama seperti morfin. Selain efek analgesik tentunya masih banyak efek fisiologis lain yang didapatkan yaitu euforia, sedasi, hipoventilasi, hipotensi, pruritus serta mual muntah. Dalam praktek klinis obat opioid ini cenderung untuk dihindari oleh karena efek samping yang berat terutama yaitu depresi nafas. Namun dalam perkembangannya, obat golongan opioid banyak disintesis dalam berbagai macam jenis untuk memberikan efek analgetik yang lebih kuat atau mengurangi efek samping yang merugikan. Artikel ini memberikan gambaran singkat tentang aspek farmakologis beberapa golongan obat opioid dan beberapa paparan praktek klinis yang akan sangat berguna baik dokter umum maupun tenaga medis yang lain. Dengan memberikan pemahaman yang baik tentang farmakologi obat opioid diharapkan terapi nyeri akan dapat lebih efektif dan efisien.

Kata kunci: opioid, reseptor opioid, praktek klinis
KORELASI TINGKAT KECEMASAN DENGAN TENSION TYPE HEADACHE
Authors: Hidayah Nurul , Silalahi Parningotan Yosi , Taihuttu Yuniasih MJ 
Published: February 2019

Pendahuluan. Tension type headache (TTH) adalah suatu gangguan neurologi yang sering dijumpai di masyarakat. Penyebab dan mekanisme TTH tidak diketahui dengan pasti. Namun, TTH sering dikaitkan dengan kondisi psikologis seperti kecemasan, depresi dan stres. Tujuan. Penelitian ini bertujuan untuk mengetahui korelasi tingkat kecemasan dengan TTH. Metode. Metode penelitian yang digunakan adalah analitik observasional dengan pendekatan cross sectional dimana data diolah dengan menggunakan software SPSS versi 16,0. Subjek penelitian adalah penderita TTH sebanyak 75 orang reponden. Pengukuran tingkat kecemasan menggunakan kuesioner Hamilton Anxiety Rating Scale (HARS). Hasil. Hasil analisis didapatkan hubungan bemakna (p=<0,001) dengan koefisien korelasi sedang dan arah korelasi positif (r=0,481). Kesimpulan. Terdapat korelasi tingkat kecemasan dengan TTH dan semakin tinggi kecemasan semakin berat pula gejala TTH yang dialami.
Kata Kunci: Korelasi, Tingkat Kecemasan, Tension Type Headache (TTH), Hamilton Anxiety Rating Scale (HARS)
RESPON IMUN SELLULER dan HUMORAL TERHADAP INFEKSI HIV
Authors: Pagaya Joseph , Que Bertha Jean 
Published: February 2019

Sistem imun terbagi menjadi dua cabang, imunitas humoral, yang merupakan fungsi protektif ditemukan pada humor dan imunitas selular, yang fungsi protektifnya berkaitan dengan sel. Orang yang terinfeksi HIV (Human Immunodeficiency Virus) membentuk respons humoral dan selular. Respons imun awal terhadap infeksi HIV mempunyai karakteristik ekspansi masif sel T sitotoksik CD8+ yang spesifik terhadap protein HIV menyebabkan terganggunya sistem alamiah dan didapat dimana yang menjadi target spesifik infeksi adalah limfosit CD4, menyebabkan lisis sel T CD4. Penyebab terpenting kurangnya sel T CD4+ pada orang terinfeksi HIV adalah efek sitopatik langsung. Respon imun selular dan humoral sama penting dalam pembentukan kekebalan terhadap infeksi virus, dimana tujuan utama respon imun terhadap infeksi virus HIV ialah eliminasi terhadap virus yang menginfeksi sel dan sel-sel yang mengandung virus atau tempat replikasi virus.
Keywords: Humoral, selluler, HIV, limfosit CD4
Tendencia, distribución geográfica y desigualdades de la mortalidad por tuberculosis en la provincia de Chaco durante el periodo 2000-2016
Authors: Genero Sebastian , Flores Eugenia Marlene , Talavera Cristian Emanuel , Riveros Ignacio , Cañete Tomás Osorio María Erica 
Published: February 2019

Objectives: To describe the tendency and geographical distribution of mortality due to tuberculosis (TB) in the province of Chaco, and analyze the life condotions of the population. Method: ecological design. General and specific mortality rates were calculated, in the rough and adjusted to world population; the tendencies of the period were analyzed through segmented regression and inequalities through concentration curve and linear regression. Results: during the period studied there were 978 deaths because of TB, mortality rate resulted in 5.4 for every 100,000 inhabitants. Risk of death was different according to sex, age and department of residence. Mortality decreased -3.6% per year (IC 95% -4.9;-2.2; p<0.05) and concentration index resulted in -0.33. Conclusion: Mortality due to TB is decreasing; however, there are inequalities that must be taken into account when planning Public Health policies.
Evaluating biologic factor at workplaces: questions and suggestions
Authors: Prokopenko Lyudmila V. , Lagutina Alla V. 
Published: February 2019

Introduction.Special evaluation of work conditions sometimes fails in identifying biologic factor as an occupational hazard in work with infected and (or) potentially infected materials (including field, clinical, autopsy samples) suspicious for presence of pathogenic biologic agents, as well as considering allergic component in biologic factor’s influence on workers exposed.Objectiveis to improve methods of identification and evaluation of biologic factor, criteria and classification of work conditions for workers exposed to pathogenic biologic agents, for more objective assessment of their work conditions.Materials and methods.Based on Rospotrebnadzor data, the authors analyzed occupational morbidity caused by exposure to biologic factors over 2005–2017. Analysis also covered work conditions of workers exposed to biologic factors, according to results of workplace certification by work conditions, performed by Testing Laboratory FGBNU «NII MT» over 2001–2013 at 1024 workplaces of medical and non-medical personnel in medical institutions of Moscow, 26 workplaces of FGBNU «N.F. Gamaleya National Research Institute of epidemiology and microbiology» with RF Health Ministry, 32 workplaces in purification facilities MGUP «Promotkhody». Analysis of the work conditions over 2014–2017 was based on results of special evaluation of work conditions at 326 workplaces (data by FGBNU «NII MT»).Results and discussion.The authors scientifically justified ways to improve quality and adequacy of work conditions evaluation by biologic factor at workplaces of individuals exposed to biologic pathogens. To objectify the work conditions evaluation by biologic factor, the authors suggested a «Classification of work conditions under exposure to biologic factor» that helped to identify and evaluate health risks with consideration of all biologic objects at the workplaces.Conclusion.Suggested «Classification of work conditions under exposure to biologic factor» helps to identify and evaluate biologic factor as an occupational hazard at all workplaces with pathogenic microbes, as well as analyze occupational health risks for workers and justify measures to minimize those risks.
Predictive model of biological equivalent radiofrequency electromagnetic field exposure assessment
Authors: Rubtsova Nina B. , Perov Sergey Yu. , Belaya Olga V. 
Published: February 2019

Introduction. The issues of radiofrequency electromagnetic field in near field human body exposure correct assessment and control methods improvement actualization determined the need to develop a predictive model that provides different exposure conditions in terms of their biological equivalence comparison.Materials and methods. The problem of laboratory rats and humans equivalent EMF exposure assessment in near and far fields was considered. It is proposed to use a set of criteria that include both the power absorption in the irradiated objects values and the exposure time, allowing to take into account the peculiarities of human body and animals species sensitivity to this factor to solve this problem.Results. Relations for RF EMF equivalent levels values calculation for concrete biological object in near and far fields are presented. There are presented the ratio to calculate EMF levels in terms of power density and energy exposure to case of human body exposure that is equivalent to experimental conditions of rats exposure.Discussion. The developed model can be used to compare the experimental conditions of exposure in the near field with PD values for far field (formed electromagnetic wave), which is most important for >300 MHz frequencies, as well as for the interpretation of EMF biological effects obtained in animal experiments to human exposure conditions assess. This provides a biologically based approach to control RF EMF intensity at any distance from the source and the comparison of the field strength levels with the PD values in the zone of the formed electromagnetic wave.Conclusion. The proposed model takes into account the physical patterns of energy absorption in different objects and differences of organisms species sensitivity to factor exposure; provides the ability to predict critical levels of irradiation for different human body organs and systems, taking into account the time of the factor exposure too.
Modern methods of physiological, hygienic and ergonomic evaluation of individual protective means
Authors: Geregey Andrey M. , Malakhova Inga S. , Moiseev Yurii B. , Ivanov Ivan V. , Glukhov Dmitrii V. 
Published: February 2019

Introduction. Topicality of the study is associated with necessity of physiologic, hygienic and ergonomic basis for methods evaluating tolerance of individual protective means.Objective is to study possible use of contemporary facilities and investigation methods for functional state of humans and their performance within physiologic, hygienic and ergonomic assessment of individual protective means.Methods. The authors used analytic methods and considered methodic issues connected with evaluation of human functional state and performance.Results. Findings are that present regulation basis evaluating influence of individual protective means on human functional state does not consider contemporary novelties in medical equipment, is outdated and requires improvement. The authors justified selection of methods that improve approaches to evaluation of individual protective means in simulated and real industrial conditions. Evidences are that medical and biologic evaluation of individual protective means should study functional state of locomotory system, cardio-respiratory and nervous systems. Ergospirometry is the most informative method to evaluate functional state of cardio-respiratory system, “movements capture” by inertial sensors is the most applicable method to evaluate influence of individual protective means on workers’ mobility, and stabilometry can add existing methods evaluating influence of individual protective means on locomotory and nervous systems.Conclusions. The studies performed can serve as a basis for improvement of prospective methods of physiologic, hygienic and ergonomic evaluation of individual protective means.
Metabolic syndrome in occupational respiratory diseases
Authors: Kuzmina Lyudmila P. , Khotuleva Anastasia G. 
Published: February 2019

Introduction.Metabolic syndrome (MS) is currently considered as aninterdisciplinary medical problem, which is due to its wide prevalence and interrelation with the development of cardiovascular diseases and type 2 diabetes. It is of interest to study the combination of MS and respiratory diseases due to their common pathogenetic mechanisms.Objectiveis to assess an importance of studying MS in patients with occupational respiratory diseases and a possibility of using laboratory parameters as risk markers for developing occupational respiratory diseases and metabolic syndrome combination.Materials and methods.The results of examination of 257 patients with occupational bronchopulmonary pathology were analyzed. Additional tests in patients with occupational asthma (OA) included levels of serum leptin and polymorphisms of inflammatory process regulation genes (interleukins–4, 6, 10, tumor necrosis factor-α, C-reactive protein (CRP), leptin receptor).Study results and discussion.MS was detected in 58.7% of patients with occupational bronchial asthma (OA), in 44.1% of patients with occupational chronic bronchitis, in 48.6% of patients with occupational COPD, and in 38.7% of patients with pneumoconiosis. MS components appeared to be associated with respiratory function parameters. Role of Gln223Arg polymorphisms of leptin receptor gene and C3872T of CRP gene in development of leptin resistance has been confirmed. Findings are that genotype CC (C174G) of IL–6 gene gets 2.5-fold increase of MS development risk (OR=2.507, 95% CI=1.045–6.017), the presence of three or more cytokine gene polymorphisms 2.4 times increases the need to use systemic steroids to control OA (OR=2.449, 95% CI=1.127–5.324).Conclusion.Measures aimed to prevent the development of metabolic disorders in workers exposed to industrial aerosol are at the same time measures to reduce the risk of developing respiratory diseases and to prevent progression of existing diseases. Using informative laboratory markers can optimize treatment and preventive measures, taking into account the individual characteristics of the organism.
Response of Plant Growth and Green Mustard (Brassica juncea L.) Yield Upon the Application of Agrobost Liquid Organic Fertilizer
Authors: Sulastri Sulastri , Sutejo Hery , Fatah Abdul 
Published: February 2019

The aim of research was to determine the effect of Agrobost liquid organic fertilizers on the growth and yields of greens mustard, and to find the proper concentration of Agrobost liquid organic fertilizer to obtain the highest yield of green mustard.The research was conducted in Sumber Rejo Village, Sub.district of Sekolaq Darat, West Kutai Regency. It was conducted from February 2016 to April 2016.The research used a single factor in a completely randomized design (CRD). The research factor wasan Agrobost Liquid Organic Fertilizer (A), with six replications. It consisted of six treatments, namely: no application of Agrobost liquid organic fertilizer or control (a0), 2 ml/l water (a1), 4 ml/l water (a2), 6 ml/lwater (a3), 8 ml/l water (a4), and 10 ml/lwater (a5).The research results revealed that the Agrobost liquid organic fertilizer treatment affected very significantly on the crop height at 2, 3, and 4 weeks after planting, leaf number at 2, 3, and 4 weeks after planting, and fresh weight per crop. The highest parameters observed (crop height, leaf number, and fresh weight per crop) were attained at a5 teratment. The highest fresh weight was attained at a5 treatment, namely 250.67 g. Meanwhile, the lowest one was attained at a0 treatment, with only 61.83 g.
KEPUASAN MAHASISWA TERHADAP MUTU PELAYANAN STAF ADMINISTRASI KEUANGAN DI AKADEMI KEPERAWATAN DIRGAHAYU SAMARINDA
Authors: Sastrini Yovita Erin 
Published: February 2019

ABSTRACTThe purpose of the study was to reveal student satisfaction with total service, service dimensions, and items of service for administrative staff in the financial section of Akper Dirgahayu. This research is a quantitative descriptive study that describes student satisfaction with financial administration services. The study was conducted from November and December 2016 at the Campus of Nursing Academy in Samarinda.The research subjects were second-level students, amounting to 185 people, and the object of the study was student satisfaction with the quality of financial part administration services at Akper Dirgahayu. Data collection uses a Likert 4 choice satisfaction questionnaire developed from 5 dimensions of service quality, namely tangibles, responsiveness, reliability, empathy, and assurance. Analysis of data describing student satisfaction with service is carried out using the Student Satisfaction Index (IKM) and percentage distribution table.The results showed that (1) student satisfaction with the service of the administrative staff of the financial section of Akper Dirgahayu belonged to the category of satisfaction, the student satisfaction index value (IKM) for the total service was 68.90 (classified as satisfied) and about 70 percent of students had satisfaction scores classified as categories satisfied and very satisfied; (2) Satisfaction with all dimensions of service and for all service items also has the value of SMIs classified as satisfied; and (3) there are a number of items including potential perceived dissatisfaction by students. These items are friendliness, ease of meeting officers, alertness asking for needs, speed of service, convenience / suitability of service procedures, officer justice, willingness of officers to help difficulties, accuracy of officer appointments, every service request is always fulfilled, and the ability of officers to provide solutions. Each of these items was perceived as dissatisfied and very dissatisfied with more than 30 percent of students.