bluuebunny/crossref_metadata_2025_split huggingface dataset:
Progesterone Supplementation During the Pre-implantation Period Influences Interferon-Stimulated Gene Expression in Lactating Dairy Cows
Authors: Serrano-Pérez Beatriz , Rizos Dimitrios , López-Helguera Irene , Molina Ester , Garcia-Ispierto Irina , López-Gatius Fernando 
Published: April 2019

Abstract
This study examined the effect of progesterone (P4) supplementation from Days 16 to 18 post-AI on interferon-stimulated gene (ISG) expression on Day 19 in high-producing dairy cows. Gene expression levels were measured in peripheral blood mononuclear cells. Possible relationships between ISG expression and the incidence of pregnancy failure were also investigated. Cows were alternately assigned on Day 16 post-AI to a control (C: n = 13) or treatment group (P4: n = 14). Out of 27 cows, 12 returned to oestrus before pregnancy diagnosis and 9 were diagnosed as pregnant on Day 28. ISG expression was assessed in all cows. Expression levels for the genes OAS1, ISG15, MX1 and MX2 were higher for pregnant than for non-pregnant cows (P=0.04; P<0.001; P=0.02; P=0.045; respectively). A significant (P=0.01) interaction was observed between the treatment and positive pregnancy diagnosis groups on Day 28 post-AI for the probability of showing ISG expression. This interaction suggests that in cows not pregnant on Day 28, P4 supplementation may have led to increased ISG15 mRNA expression on Day 19. Lower ISG15 expression was detected for cows returning to oestrus than for pregnant cows (P<0.001). However, cows with a negative pregnancy diagnosis showed intermediate values, differences being non-significant when compared to cows returning to oestrus or pregnant cows. Our results suggest that P4 supplementation during the pre-implantation period promotes conceptus signalling.
Evaluation of Supplementation of Defatted Black Soldier Fly (Hermetia illucens) Larvae Meal in Beagle Dogs
Authors: Lei X.J. , Kim T.H. , Park J.H. , Kim I.H. 
Published: April 2019

Abstract
The objective of this experiment was to test the effects of supplementation of defatted black soldier fly (Hermetia illucens) larvae (BSFL) meal in beagle dogs. A total of nine healthy female beagles (initial body weight 12.1 ± 1.76 kg) were fed grain-based diets with three levels of BSFL meal (0, 1% or 2%) in a 42-day feeding trial. At the end of week 6 of the experiment, all dogs were intraperitoneally challenged with Escherichia coli lipopolysaccharide (LPS) at 100 μg/kg of body weight. Albumin concentration was linearly increased with increasing BSFL meal level (P<0.05). A linear increase (P<0.05) in calcium concentration was observed when increasing dietary BSFL meal. Although dietary treatments did not affect the digestibility of ether extract, the digestibility of dry matter and crude protein were linearly increased with increasing the level of BSFL meal. The concentration of tumor necrosis factor-α was linearly decreased but glutathione peroxidase (GPx) concentration was linearly increased when increasing the level of BSFL meal at 6 h after challenge (P<0.05). In addition, there were quadratic increases in concentrations of GPx and superoxide dismutase with increasing dietary BSFL meal level at 3 h after challenge (P<0.05). These findings from the present study demonstrate that BSFL meal can be supplemented in the diet to convert beneficial effects to beagle dogs, indicated as improved digestibility of dry matter and crude protein and anti-inflammatory and anti-oxidative capacity.
Structure–Property of Wet-Spun Alginate-Based Precursor Fibers Modified with Nanocarbons
Authors: Szparaga Grzegorz , Brzezińska Magdalena , Pabjańczyk-Wlazło Ewelina , Puchalski Michał , Sztajnowski Sławomir , Krucińska Izabella 
Published: April 2019

Abstract
The results of studies assessing the influence of the addition of carbon nanofillers, such as multiwalled carbon nanotubes (MWCNTs) and graphene oxide (GO) that differ in size and structure, on the molecular and supramolecular structure and properties of alginate fibers that might be prospective precursors for carbon fiber (PCF) industry are presented in this article. The investigation was carried out by Fourier transform infrared (FTIR) spectroscopy, wide-angle X-ray diffraction (WAXD), and tension testing. In the frame of the current study, two types of alginate fibers were examined and compared: alginic acid and calcium alginate fibers. Alginic acid fibers were formed by chemical treatment of calcium alginate fibers with hydrochloric acid due to the fact that Ca2+ ions presented in the fibers were expected to adversely affect the prospective carbonization process. This investigation brought important conclusions about the influence of nanofillers on the physical properties of the final material. Understanding the link between the incorporation of carbon nanostructures and a possible influence on the formation of ordered carbon structures in the precursor fibers brings an important opportunity to get insights into the application of alginate fibers as a prospective base material for obtaining cost-efficient carbon fibers.
Mechanism of Electrical Conductivity in Metallic Fiber-Based Yarns
Authors: Xie Juan , Miao Menghe , Jia Yongtang 
Published: April 2019

Abstract
We explore the conductive mechanism of yarns made from metallic fibers and/or traditional textile fibers. It has been proposed for the first time, to our knowledge, that probe span length plays a great role in the conductivity of metallic fiber-based yarns, which is determined by the probability and number of conductive fibers appearing on a cross section and their connecting on two neighboring sections in a yarn’s longitudinal direction. The results demonstrate that yarn conductivity is negatively influenced to a large extent by its length when metallic fibers are blended with other nonconductive materials, which is beyond the scope of conductivity theory for metal conductors. In addition, wicking and wetting performances, which interfere with fiber distribution and conductive paths between fibers, have been shown to have a negative influence on the conductivity of metallic fiber-based yarns with various structures and composed of different fiber materials. Such dependence of the conductivity on the probe span length, as well as on the moisture from air and human body, should get attention during investigation of the conductivity of metallic fiber-based composites in use, especially in cases in which conductive yarns are fabricated into flexible circuit boards, antennas, textile electrodes, and sensors.
Influence of Modified Cationic Starch in a Mixed Poly(Vinyl Alcohol)/Cationic Starch Solution on the Electrospinning Process and Web Structure
Authors: Šateikė Jurgita , Milašius Rimvydas 
Published: April 2019

Abstract
Nanofibers were electrospun from bicomponent poly(vinyl alcohol) (PVA) and modified cationic starch (CS) mixed solution PVA/CS with different mass ratios (75/25, 50/50 and 35/65) at a total concentration of 12 wt% for all polymer compositions. For comparison, pure PVA solution was used. Electrospinning technique Nanospider (Elmarco, Czech Republic) with a rotating electrode with tines was used to obtain nanofibrous web. The influence of prepared polymer solution compositions on the structure and morphology of nanofibers and webs were investigated. Analyzing the structure and morphology of the formed nanofiber webs, it was noticed that the fineness nanofibers were formed from the PVA/CS solution with a mass ratio of 50/50. This ratio of solution also lets us to obtain the nanofibrous web with less sticked nanofibers on spunbond. The increase in the CS ratio by more than 50/50 had a negative influence on the diameter of nanofibers and the structure of nanofibrous web.
Distance to Radiotherapy and Demand – Projection of the Effects of Establishing New Radiotherapy Facilities in Poland by 2025
Authors: Czerwiński Adam Michał 
Published: April 2019

Abstract
In 2015, the Ministry of Health of the Republic of Poland introduced the Polish strategic plan for radiotherapy development and investment. Given that radiotherapy utilisation depends on the distance a patient must travel to undergo the treatment, the main goal of the plan was to increase equitable access to radiotherapy in Poland by establishing new facilities in new locations by 2025. This study constitutes the first step towards an economic evaluation of this plan by adopting spatial interaction models to project the expected increase in the demand for radiotherapy (3%). Moreover, it adds to the current research on the relation between distance and demand for healthcare services in the following ways. First, it flags the importance of using spatial econometrics to healthcare utilisation studies in the presence of spatial autocorrelation. Furthermore, it proposes a quantitative method for assessing the expected impact of establishing new facilities on utilisation. Finally, it formally confirms the dependence between radiotherapy utilisation and distance in Poland, which has been previously shown to exist in other countries.
The development of HPLC-DAD method for determination of active pharmaceutical ingredient in the potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio) acetate substance
Authors: Shcherbyna Roman , Parchenko Volodymyr , Varynskyi Boris , Kaplaushenko Andriy 
Published: April 2019

Abstract
Derivatives of 1,2,4-triazole are actively researched by scientists and synthetic pharmacologists. The last studies have shown that potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio)acetate with low toxicity series exhibits antioxidant and hepatoprotective properties. Therefore, the purpose of this work was to develop a method for determining the API in the potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio)acetate substance using the method of high-performance liquid chromatography with diode array detection (HPLC-DAD). As a result of this work, it is shown that the developed method is specific and meets the requirements of linearity, accuracy and precision. The results of determining the contents of the API in real samples indicate that the method can be proposed to control the quality of the potassium 2-((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3-yl)thio)acetate substance.
Acute liver injury in the course of lymphoplasmacytic lymphoma
Authors: Kuzemko-Baranowska Dorota , Baranowski Dariusz , Prystupa Andrzej 
Published: April 2019

Abstract
Non-Hodgkin lymphomas are malignant neoplasms whose incidence rates increase each year. These also include neoplasms rare in the general population. The present case report described a patient with lymphoplasmacytic lymphoma (LPL) and rapid liver damage. In most cases, infiltration of the liver is rare in advanced stages of hematopoietic malignancies when hepatomegaly, cholestatic jaundice and organ failure are observed. The patient’s history includes non-specific abdominal pain that was accompanied by general symptoms such as nocturnal hyperhidrosis, subfibrile temperature and fever, as well as weight loss. The above complaints aggravate with an increase in organ size. The laboratory findings initially demonstrated moderately elevated concentrations of transaminases. In our case, the baseline biochemical indices of liver function were found to be normal. During the next days of hospitalisation, the features of liver damage intensified and were accompanied by liver failure. The gold diagnostic standard is a biopsy of the bone marrow and the organ affected. Since the patient’s condition deteriorated and liver failure developed, the diagnosis was established based on trephine biopsy of the bone marrow. Chemotherapy was implemented; despite the treatment applied, the patient’s clinical condition did not improve. Two months after the onset of first symptoms the patient died.
Effect of tirapazamine on selected kidney parameters in rats treated with cisplatin
Authors: Sysa Marcin , Pawlowski Kamil , Slabczynski Piotr , Burdan Franciszek , Dudka Jaroslaw 
Published: April 2019

Abstract
Hypoxic cancer cells are more aggressive and responsible for more efficient metastasis and recurrence. It seems worth-while, hence, to supplement current cytostatic drugs therapy (i.e. cisplatin) with hypoxia cytotoxic agents (i.e. tirapazamine), the toxicity of which is activated by hypoxia. Cisplatin and tirapazamine can change a redox equilibrium and consequently lead to changes in cell metabolism, fibrosis and apoptosis. The aim of this study was to evaluate the cisplatin/tirapazamine toxicological synergism. In doing so we tested selected kidney oxidative stress parameters, as well as nephrotoxicity markers, in plasma and urine. Once a week for 6 weeks, rats received intraperitoneally two doses of tirapazamine (5 or 10 mg/kg bw), 2 hours before cisplatin (2 mg/kg bw) was applied. Our results show that Tirapazamine (TP) had no significant adverse effect on the redox balance, oxidative stress and kidney function in rats receiving cisplatin (CP). However, TP significantly increased protein concentration in the kidneys of rats. In all tested groups, a significant decrease in NADH concentration in kidneys was recorded, which could indicate disorder in the cell metabolism. TP also was found to have prevented bacterial infection caused by CP. In summary, there was no nephrotoxic synergy of TP with CP at an unacceptable level.
Asymptomatic traumatic neuroma
Authors: Wrona Katarzyna , Mocarska Agnieszka , Wrona Wojciech , Grzycka-Kowalczyk Luiza , Burdan Maciej , Falek Artur , Karbownik Adrian , Burdan Franciszek 
Published: April 2019

Abstract
A rare case of asymptomatic traumatic neuroma, triggered by the performed amputation within the right thigh due to the osteosarcoma is reported. The MRI examination has shown a focal lesion at the end of the sciatic nerve, with isointense signal and weak contrast enhancement on T1-, high signal on T2-weighted images, without restriction diffusion on DWI. The morphology did not significantly change after 12 months, which confirms the primary diagnosis. The main limitation of the case is the lack of histological confirmation, since the lesion was not removed.
Evaluation of interleukin-6 concentration in the liver of Albino Swiss mice after intoxication with various doses of patulin
Authors: Borzecki Pawel , Borzecka Agnieszka , Chylinska-Wrzos Patrycja , Lis-Sochocka Marta , Wawryk-Gawda Ewelina , Jodlowska-Jedrych Barbara 
Published: April 2019

Abstract
Patulin is a mycotoxin produced by many species of the fungi. The toxic action of patulin mainly affects the gastrointestinal tract and the immune system. The aim of our work was to assess the toxic effect of patulin, based on the analysis of interleukin IL-6 concentrations in the liver of test animals loaded with different doses of this mycotoxin. The research was conducted on mice which were assigned to 6 groups receiving different doses of active substances. After decapitation, their livers were taken for laboratory testing.
Our studies have shown that chronic intoxication with patulin at 0.1 LD50 leads to a statistically significant increase in IL-6 concentration in the liver of the animals. We also found that the loading of experimental animals with a single dose of patulin in the amount of 0.5 LD50 and 0.2 LD50 also leads to a statistically significant increase in this interleukin in the examined organ. There was no difference in its concentration compared to the control group only after the single dose of the lowest concentration of patulin, while the highest average IL-6 concentration was recorded in the liver of animals loaded with the highest single dose of patulin. After applying, one-time doses of this mycotoxin in the amount of 0.2 LD50 and 0.1 LD50, the mean concentrations of IL-6 in the liver in animals from these groups were statistically significantly lower.
In conclusion, the analysis of the obtained results confirms the fact of the hepatotoxic effect of patulin.
Meristic and Morphometric Variations of Barred Spiny EEL Macrognathus pancalus Populations from Bangladeshi Freshwaters: An Insight Into Landmark-Based Truss Network System
Authors: Sarower-E-Mahfuj Md. , Khatun Ambia , Boidya Puja , Samad Md. Abdus 
Published: April 2019

Abstract
The present research focuses to examine the meristic and landmark-based morphometric variations of barred spiny eel Macrognathus pancalus from four populations namely Dhakuria beel, Jessore (DBJ); Bohnni boar, Gopalgonj (BBG); the Arial kha river, Madaripur (AKRM) and the Nabaganga river, Jhenidah (NRJ) in Bangladeshi freshwaters. Six meristic counts were compared among four populations and significant differences were observed in number of caudal fin rays and number of pelvic fin rays in all meristic characters. The truss protocol was used in the present study based on six general morphometrics and fifteen truss measurements. Univariate statistics showed that five (standard length (SL), upper jaw length (UJL), lower jaw length (LJL), head depth (HD) and inter orbital (IO)) of six morphometric and eleven truss networks (viz. 2-3, 3-4, 5-6, 6-7, 7-8, 1-8, 2-8, 3-8, 3-7, 4-7 and 5-7) among fifteen truss measurements differed significantly. Cannonical discriminate function analyses were conducted among samples and the populations were fully intermingled. Pooled within-group correlation showed morphometric and landmark measurements; the first discriminant function (DF) accounted for 79%, the second DF accounted for 15.9% and third DF accounted for 5.1% of group variability. An euclidian dendrogram was prepared based on morphometric and truss measurements in four populations, where two clusters were mainly formed, in which first cluster formed by NRJ population was fully separated, and the second cluster was formed by two populations of AKRM and DBJ. Additionally, a subcluster BBG was formed with AKRM. On the basis of morphometric and truss measurements, 68.8%, 83.6%, 55.6% and 80% of original grouped cases were correctly classified in NRJ, AKRM, DBJ and BBG, respectively. These results specify the presence of different stocks of fish from four aquatic habitats. This study is highly significant for proper conservation and effective management of M. pancalus populations as well as for the scientific community for further research.
The Problem of Plastic Waste and Microplastics in the Seas and Oceans: Impact on Marine Organisms
Authors: Kurtela Antonia , Antolović Nenad 
Published: April 2019

Abstract
A global problem of today is the large amount of waste in the seas and oceans, primarily plastic waste. It is estimated that every year 1.25 to 2.41 million tons of plastic material is being carried by rivers into the seas and oceans. Waste is a major problem for marine organisms, causing entanglement, choking, strangulation, malnutrition and death. In 1972 the problems caused by microplastics, particles smaller than 5 mm, were first observed. Such particles bind pathogenic microorganisms on to their surface. Increasing quantities of microplastics have been found in the stomachs of fish, and also in shellfish that feed by filtering sea water. Ingested by marine organisms, such plastics may eventually pass through the food web and can end up ingested by humans. In addition, plastic releases chemical compounds whose effect on marine organisms and humans has still not been studied. Many international and state organizations offer solutions through recycling plastic waste, as well as reducing the production of plastic materials and informing the public about the problem.
Relationships Between Otolith Dimensions and Body Growth of North African Catfish Clarias gariepinus (Burchell, 1822) from the Upper Basin of the Sakarya River, Turkey
Authors: Yılmaz Savaş , Emiroğlu Özgür , Aksu Sadi , Başkurt Sercan , Polat Nazmi 
Published: April 2019

Abstract
The relationships between otolith size and body length of North African catfish Clarias gariepinus (Burchell, 1822), collected from Sakaryabaşı (the main spring area of the Sakarya River) between July 2014 and November 2014, were examined. Length-weight relationship was also calculated for overall specimens. The wild fish were captured by electrofishing using SAMUS 725MP. A total of 132 individuals ranging from 13.6 to 59.0 cm in total length and from 15.9 to 1755.0 g in weight were sampled. The lagenar otolith (asteriscus) length and height, and the utricular otolith (lapillus) length and width were recorded for each fish. The relationships between otolith measurements and fish somatic growth were described by a non-linear function (power model). The t test revealed no considerable differences in these relationships between left and right otoliths. The ANCOVA test on the relationships between total length and otolith variables did not show significant differences between females and males. All relationships were highly significant and the mean percent prediction errors were less than 7%. The results showed that otolith growth reflected body growth.
’Jakeš’s Children’. Media Portrayal of Namibian Child Refugees in Slovakia
Authors: Jakubcová Martina 
Published: April 2019

Abstract
The paper provides an insight into ‘Slovak group’ of Namibian children taken to Czechoslovakia. As a form of a communist solidarity help to the country fighting for its freedom, the children were raised and educated in newly established boarding school in Považská Bystrica from September 1989. Their stay, and particularly their sudden unexpected repatriation in 1991, raised questions not only among general public, but also in print media of those days. The article therefore discusses the media portrayal of the Slovak group of Namibian children with a special accent on the shifts in media interpretations in time. The overall research combines a biographical and historical design with the use of the qualitative analysis of print media outputs.
Gurraacha: An Indigenous Inter-Ethnic Peace Building and Conflict Resolution Institution among the People of South Central Ethiopia
Authors: Kuto Lenin , Bacha Ayehu , Taye Gemechu 
Published: April 2019

Abstract
This article deals with Gurraacha institution, which is very important in inter-ethnic peace building and resolving conflict among people of south-central Ethiopia. This institution was named after the Oromo term ‘Gurraacha’ (literally meaning black) to indicate its power in inter-ethnic peace building and conflict resolution. It is one element of Oromo Gadaa system which was established time immemorial to sustain peace between Oromo and non-Oromo neighboring ethnic groups. The data for this study was collected through interview, observation and focus group discussions in 2014 and 2015. As revealed by this study, Gurraacha institution is a guarantee for sustaining peace among people of south-central Ethiopia by managing conflict over boundary, grazing land, looting of cattle and water points. Overall, the study concluded that Gurraacha institution has real significance in inter-ethnic peace-building, sustaining social harmony and inter-ethnic conflict resolution. In Gurraacha institution, people rebuild lost peace and order of Waaqa (God) by performing purification rituals. There is no corruption in Gurraacha institution since all activities are undertaken according to Waaqa’s law and order. There is no false oath in this institution because such act is believed to have negative consequences. The oath of Gurraacha institution which are made during reconciliation process transcend generations. This institution is the model of conflict transformation which is hardly found in today’s world. Therefore, using this indigenous institution for future policy formulation in the country as inter-ethnic peace building and conflict resolution model is important for the realization of sustainable peace and development.