bluuebunny/crossref_metadata_2025_split huggingface dataset:
Saúde do homem: um estudo realizado na unidade de saúde da pedreira em Belém, Pará
Authors: De Cristo Dorotéa Albuquerque , De Cristo Solange Conceição Albuquerque 
Published: August 2019

Justificativa:
Este artigo é resultado de pesquisa que investigou como homens avaliam o serviço da atenção primária de um bairro em Belém, suas concepções de autocuidado e as motivações para aderirem a esse serviço que objetiva a prevenção de doenças e promoção da saúde. Através de suas percepções pode-se chegar também aos motivos das ausências da maioria dos homens na Atenção Primária. Pelas estatísticas do Ministério da Saúde, os homens adentram a saúde pela alta e pela média complexidade, quando doenças e agravos já estão instalados.

Método:
O estudo é qualitativo, de natureza fenomenológica, considerando a relação sujeito e mundo, e foi realizado com 10 homens, na faixa etária de 19 a 59 anos, usuários de uma unidade básica de saúde (UBS), atendidos no setor da clínica. As categorias de análise foram: importância da Atenção Primária para sua saúde, atendimento prestado na Unidade de Saúde da Pedreira, suas necessidades de saúde e práticas de autocuidado. Outros fatores relevantes no contexto do estudo foram: relações com o trabalho e com a família.

Resultados:
Os resultados mostraram que os motivos da adesão são sinais e sintomas de doenças e agravos e recomendação de atendimento na UBS por parte de terceiros. Vários sentidos foram captados: receio, responsabilização, vergonha e irritabilidade por estarem doentes. Ter que esperar, ter que abrir mão do que percebem como prazeroso, dentro de um universo de situações adversas.

Conclusões:
O estudo apontou que os usuários da UBS Pedreira não se percebem como invulneráveis, temem as doenças e não frequentam espaços de saúde para não vivenciarem a dor, como se a doença passasse a ter existência real a partir de sua presença nos serviços, com isso evitam procurar ajuda, mesmo diante de sintomas. Como o espaço privilegia as medidas curativas, e não a promoção de saúde, os homens continuam afastados do serviço.
Une sémantique du discours « au travail » de l’actualité : éléments pour l’analyse du discours des médias
Authors: Moirand Sophie 
Published: August 2019

Cette contributionvoudrait montrer comment le traitement de l’actualité par les médias professionnels (presse quotidienne, imprimée ou en ligne, chaînes d’information continue,sites en ligne des journaux, notifications sur les téléphones portables ou les tablettes)conduit à « repenser » l’analyse du discours d’origine française ainsi que les études de discours médiatiques.L’orientation de l’analysevers une sémantique du discours, qui prenne en charge le passage du virtuel et du possible à l’actuel et son articulation au déjà-là (ce qui caractérise le discours de« l’actualité » : les Cahiers Sens Public21-22, 2018, en ligne), conduitégalement à re-visiter le traitement de l’événement au fil de la médiatisation de son déroulement, et de ses différentes temporalités.
Quebra-cuca: Desenvolvimento e avaliação de um jogo educacional para o ensino da matemática
Authors: Gomes José Adriano Cajado , Carvalho Elielton da Costa , Silva Francisco Adriano Cavalcante da , Garcia Fabrício Wickey da Silva , Yasojima Edson Koiti Kudo 
Published: August 2019

Ferramentas educacionais são utilizadas há décadas no contexto escolar, porém com o advento das tecnologias, em especial a computação, essas ferramentas foram sendo modificadas e/ou atualizadas, tornando-se mais interativas e lúdicas, atraindo um público cada vez mais conectado. Pensando nesse contexto, o presente trabalho traz uma descrição simplificada concernente ao desenvolvimento e aplicação do jogo matemático Quebra-cuca, o qual foi idealizado após uma pesquisa sobre a necessidade e a utilidade de jogos educacionais no contexto amazônico. Neste trabalho, apresentamos alguns dados a respeito dos testes, além de trazermos uma breve contextualização sobre a situação da educação brasileira, falando brevemente sobre a inclusão digital nas escolas, um assunto amplamente discutido atualmente.
Desenvolvimento do Pensamento Computacional no Ensino Superior
Authors: Karling Daniel Antonio , Lisbôa Eliana Santana 
Published: August 2019

O desenvolvimento do pensamento computacional constitui um dos grandes desafios para alunos no ensino superior, visto que os conceitos relacionados a esse campo não são trabalhados nas séries iniciais do Ensino Fundamental. Quando chegam ao ensino superior, principalmente nos cursos de computação, a maioria desses alunos, por possuir essa lacuna em sua formação, enfrenta muitas dificuldades em disciplinas que necessitam de um poder de abstração maior e requerem competências no que diz respeito à capacidade de resolução de problemas, habilidade analítica etc. Face a essa questão, no presente relato, apresenta-se um estudo que envolveu alunos do curso de Licenciatura em Computação na construção de aplicativos para Android, utilizando a plataforma App inventor como estratégia pedagógica para o desenvolvimento do pensamento computacional. O embasamento teórico introduziu o debate acerca do pensamento computacional, bem como os principais aspectos da Plataforma App Inventor. Em termos metodológicos, foram adotadas técnicas de abordagem exploratória, por ser esse o primeiro estudo realizado no Curso de Licenciatura em Computação, aplicação de oficinas que envolveram o conhecimento e utilização da plataforma App inventor. Para avaliar os aplicativos desenvolvidos, optou-se pela avaliação por pares, mediante rubricas nas quais os próprios alunos julgaram os trabalhos dos colegas e também por meio de análise conjunta das atividades. Os resultados apontam que a atividade representou um ganho cognitivo satisfatório, contribuindo para que os alunos participantes aprendessem conceitos abstratos de forma lúdica e engajada.
Orientação On-line Idiomas sem Fronteiras - Inglês: relato de experiências de 2018
Authors: Braga Junia de Carvalho Fidelis , Dellagnelo Adriana Kuerten , Souza Valeska Virgínia Soares 
Published: August 2019

Neste relato de experiências, apresentamos a proposta metodológica da orientação on-line de professores de língua inglesa em formação, que atuam em diferentes Núcleos de Línguas (NucLis) do Idiomas sem Fronteiras - Inglês. Iniciamos com uma breve descrição sobre o Programa Idiomas sem Fronteiras (IsF) e sobre a implementação da orientação pedagógica on-line. Na sequência, discorremos sobre o contexto em que desenvolvemos a proposta metodológica para 2018, baseando-nos em experiências anteriores. Apresentamos a proposta de orientação pedagógica denominada por nós como “Exploring How-tos in English teaching: Focus on Academic English and English for Internationalization”, explicitando os temas abordados, os textos teóricos e as referências de webinars utilizados. Finalizamos relatando o que aprendemos ao longo da implementação da proposta e indicando o que manteríamos e o que mudaríamos em novas oportunidades de utilização da proposta.
CORPO EM CENA: uma Poética (Des)velada da Rostidade
Authors: Da silva Renata Ferreira 
Published: August 2019

Aqui partilho, de forma figurada, uma poética Â que re(vela) um treinamento cênico de experimentações dado por um véu que cobre o rosto. Â Mostro figuras de véu nas quais improviso cenas em silêncio com o rosto coberto. Em seguida, implico as sensações do corpo ao conceito operativo de rostidade de Gilles Deleuze para, sensivelmente, desfazer esse rosto e encontrar outros modos de corpo em cena na relação com a mímica de Ettiénne Decroux.
Critical elliptic systems involving multiple strongly–coupled Hardy–type terms
Authors: Kang Dongsheng , Liu Mengru , Xu Liangshun 
Published: August 2019

AbstractIn this paper, we study the radially–symmetric and strictly–decreasing solutions to a system of critical elliptic equations in RN, which involves multiple critical nonlinearities and strongly–coupled Hardy– type terms. By the ODEs analysis methods, the asymptotic behaviors at the origin and infinity of solutions are proved. It is found that the singularities ofuandvin the solution (u,v) are at the same level. Finally, an explicit form of least energy solutions is found under certain assumptions, which has all of the mentioned properties for the radial decreasing solutions.
Clinical significance of neuropeptide Y expression in pelvic tissue in patients with pelvic floor dysfunction
Authors: Zhang Limin , Luo Xin 
Published: August 2019

AbstractObjectivesTo investigate the neuropeptide Y (NPY) expression in the tissue of pelvic floor ligament and anterior vaginal wall in female patients with pelvic organ prolapse (POP) and stress urinary incontinence (SUI).MethodSeventeen patients with POP, 6 with SUI, 13 with POP and SUI (POP&SUI), and 10 controls were included in this study from First Affiliated Hospital of JiNan University. Immunohistochemical assay was used to examine NPY expression in the tissue of round ligament, cardinal ligament of uterus, uterosacral ligament, and anterior vaginal wall. NPY expression were compared between POP, SUI, POP&SUI and controls.ResultsNPY was positive expressed in the round ligament, cardinal ligament of uterus, uterosacral ligament, and anterior vaginal subepithelial connective tissue. Compared with the control group, NPY expression in the round, cardinal, and uterosacral ligaments in patients with POP&SUI group was decreased with significant statistical difference (p<0.05). NPY expression in anterior vaginal wall was significantly decreased in POP, SUI, and POP&SUI groups compared to normal group (p<0.05). Compared to POP group, NPY expression in SUI and POP&SUI groups were significantly decreased (p<0.05), however the difference was not statistical different between SUI and POP&SUI groups (p>0.05). In POP and POP&SUI groups, the NPY expression in the cardinal ligament of uterus, uterosacral ligament, and anterior vaginal wall were negatively correlated with age (p<0.05), however, was not correlated with number of pregnancy, number of delivery, and BMI (p>0.05).ConclusionsNPY expression was reduced in the round ligament, cardinal ligament of uterus, Uterosacral ligament, and vaginal anterior wall of the patients with POP and SUI. The decreased NPY expression may play an important role in the development of pelvic floordysfunction.
Influence of the Static Magnetic Field and Algal Extract on the Germination of Soybean Seeds
Authors: Lewandowska Sylwia , Michalak Izabela , Niemczyk Katarzyna , Detyna Jerzy , Bujak Henryk , Arik Pelin 
Published: August 2019

AbstractThis study examines the effect of a separate static magnetic field (SMF) and algal extract and their synergistic effect on soybean seeds germination. To our knowledge, this is the first time these kinds of factors were used for the biostimulation of soybean seeds germination. Soybean –Glycine max(L.) Merrill variety ‘Merlin’ was used in the present study. The exposure of seeds to the magnetic field was applied for 3, 6 and 12 min. The algal extract, produced from a freshwater green macroalga –Cladophora glomeratausing an ultrasonic homogenizer, was used directly to the paper substrate at a dose of 10%. The highest germination ability of soybean seeds was observed in a group, where the magnetic field (12 min.) was used together with 10% of algal extract. However, it was very low – only 21%, which may have resulted from the seed dormancy. Future experiments on soybean seeds are required to confirm the stimulation effect of the magnetic field (various induction values) and algal extract on seeds germination.
A new solution of the semi-metallic gasket increasing tightness level
Authors: Jaszak Przemysław 
Published: August 2019

Abstract
The paper presents new type of the semi-metallic gasket characterized with elastic core. Thanks to this solution more elastic recovery as well as more uniform contact stress distribution on the gasket’s surface were obtained which consequently caused that tightness level of the flange joint increased by 1000% in contrast to joint gasketed with traditional solution. The tightness characteristic of the traditional as well as new solution of the gaskets were determined experimentally and discussed.
From Theory to Practice to Problem: Teaching Public History with a Real Client
Authors: Thomas Adam Adrian 
Published: August 2019

AbstractIn many ways, teaching public history through real-world projects is a panacea. After all, a properly trained graduate of a public history program should be able to leave the theoretical world of the university and shift confidently into the exigencies of professional practice. But many educators naturally shy away from this approach because it is fraught with potential disasters – the looming threat of the unknown that frustrates students, educators, and partners alike. Flexibility and adaptability are keys to developing successful real-world public history projects. Accepting or even welcoming the unanticipated provides valuable teaching moments and a sense of reality that is difficult to duplicate in the classroom. Moreover, crafting a flexible but ultimately successful student project requires identifying the right partner or client while tempering expectations with a thoughtful and realistic scope of work.
Negotiating Public Participation through Dance and Drama Techniques: A Roundtable Discussion on the Challenges of Public History Work by the Isikhumbuzo Applied History Unit in South
Authors: Hellemann Phemelo C. 
Published: August 2019

AbstractThe Isikhumbuzo Applied History Unit (IAHU) of Rhodes University History Department specializes in innovative methodologies for bringing historical information closer to non-academic audiences. The National Research Foundation of South Africa funds the research work conducted by Isikhumbuzo Applied History Unit. This article shares insights from a reflective discussion that took place February 4, 2019 at Rhodes University. The team reflects on the challenges of doing Public History work in South Africa, particularly drawing attention to the issues surrounding academics and the public when it comes to engaging in research and storytelling exercises that unearth untold stories.Experimenting with creative arts such as drama and dance as strategies that can improve public participation in historical work, the team discusses how they are bridging the gap between the public, artists, and academics. The views expressed in this roundtable discussion contribute to the reflexive nature of the methodology employed by the Isikhumbuzo Applied History Unit.
An Overview of Public History in Italy: No Longer A Field Without a Name
Authors: Noiret Serge 
Published: August 2019

AbstractThis article traces the origins and development of public history in Italy, a field not anymore without this name today. Public history in Italy has its roots in historical institutions born in the nineteenth century and in the post WW2 first Italian Republic. The concept of “public use of history” (1993), the important role played by memory issues in post-war society, local and national identity issues, the birth of public archaeology (2015) before public history, the emergence of history festivals in the new millennium are all important moments shaping the history of the field and described in this essay. The foundation of the “Italian Association of Public History” (AIPH) in 2016/2017, and the promotion of an Italian Public History Manifesto (2018) together with the creation of Public History masters in universities, are all concrete signs of a vital development of the field in the Peninsula.
Extinction of a two species competitive stage-structured system with the effect of toxic substance and harvesting
Authors: Huang Xiaoyan , Chen Fengde , Xie Xiangdong , Zhao Liang 
Published: August 2019

Abstract
The extinction property of a two species competitive stage-structured phytoplankton system with harvesting is studied in this paper. Several sets of sufficient conditions which ensure that one of the components will be driven to extinction are established. Our results supplement and complement the results of Li and Chen [Extinction in periodic competitive stage-structured Lotka-Volterra model with the effects of toxic substances, J. Comput. Appl. Math., 2009, 231(1), 143-153] and Liu, Chen, Luo et al. [Extinction and permanence in nonautonomous competitive system with stage structure, J. Math. Anal. Appl., 2002, 274(2), 667-684].
Incidental findings in dental radiology are concerning for family doctors
Authors: Monsarrat Paul , Galibourg Antoine , Nasr Karim , Telmon Norbert , Maret Delphine 
Published: August 2019

Abstract
Cone Beam Computerized Tomography (CBCT) is an imaging technology increasingly used in dentistry. Depending on the size of the examination area, visualization of anatomical structures outside the indication area may reveal incidental findings (IF). The aims of this systematic review and meta-analysis were to 1) evaluate the frequency, location and different types of incidental findings (IF) revealed during CBCT examinations; 2) identify potential influencing factors such as gender or age; 3) highlight what the family doctor should know about CBCT and the benefits for medical care.
70 retrospective studies were included. 60% of IF are in the naso-oropharyngeal airway and paranasal sinuses. Carotid calcifications were observed with a mean prevalence of 9% CI95% [2-21]). Meta-regression showed a significant association of this prevalence with age, irrespective of gender.
Given the high frequency of IF, with varying severity, the whole medical community is fully involved, and its opinion should be sought to ensure the best possible management for the patients. Physicians may also require CBCT examinations that would have been previously prescribed by a dentist, that may serve to better orientate investigations toward another imaging technique. The family doctor is therefore the dentist’s main interlocutor and the main coordinator of the follow-up of IF.
Osteopontin and fatty acid binding protein in ifosfamide-treated rats
Authors: Dobrek Łukasz , Arent Zbigniew , Nalik-Iwaniak Klaudia , Fic Kinga , Kopańska Marta 
Published: August 2019

Abstract

Introduction
Ifosfamide (IF) is a cytostatic that exhibits adverse nephrotoxic properties. Clinically, IF-induced nephrotoxicity takes various forms, depending on applied dose and length of treatment.

Objectives
The aim of the study was to evaluate the two proteins: osteopontin (OP) and fatty acid binding protein (FABP), as markers of kidney function in rats treated with ifosfamide.

Material and Methods
Rats receiving a single IF dose (250 mg/kg b.w.; group 1) or treated with five consecutive IF doses administrated on following days (50mg/kg b.w.; group 3), compared with control groups 2 and 4, respectively, were studied. Kidney function was assessed using classical (urea, creatinine) and novel (FABP, OP) laboratory parameters and by histopathology.

Results
Single IF dose administration resulted in significant total proteinuria with urinary concentrations and 24-hour excretions of both FABP and OP comparable to the appropriate control. In rats treated with five consecutive IF doses, the urinary concentrations and 24-hour excretion of both FABP and OP were significantly higher compared to the appropriate control. The development of cystitis was revealed in groups 1 and 3, which was not accompanied by significant histopathological kidney damage.

Conclusions
Both OP and FABP may be useful laboratory markers of tubulopathy in the early stage of chronic nephrotoxicity of ifosfamide.
Familial polyposis coli: the management of desmoid tumor bleeding
Authors: Calogero Armando , Sagnelli Caterina , Carlomagno Nicola , Tammaro Vincenzo , Candida Maria , Vernillo Antonio , Peluso Gaia , Minieri Gianluca , Sica Antonello , Ciccozzi Massimo , Santangelo Michele , Dodaro Concetta Anna 
Published: August 2019

Abstract

Background
There is currently no standard treatment for desmoid tumors (DTs) associated with familial polyposis coli (FAP). Familial adenomatous polyposis in DT patients is sometimes a life-threatening condition.

Methods
We enrolled all consecutive patients with FAP treated at Unit of General Surgery and Transplant, University of Naples Federico II and evaluated the incidence of DTs on FAP between 1996 and 2016.

Results
We observed 45 consecutive patients with FAP; of these 5 were DT-FAP-associated. All 5 cases with FAP were young women, age 25 to 65 years, previously treated by colectomy. Of these, 4 patients presented a parietal localization and had been treated with a wide surgical exeresis; one patient had an intra-abdominal, mesenteric tumor that was unresectable at laparotomy. We performed CT-guided drainage, ureteral stenting, medical therapy (sulindac+tamoxifene), and chemotherapy (dacarba-zine+doxorubicine).
All patients were alive and underwent follow-ups for 5 years post-surgery; only 1 patient with parietal localization showed a local relapse after 2 years.

Conclusions
We propose a modulated approach to the single patient with FAP, with surgery as treatment of choice for parietal localization disease and integrating different kinds of therapies (surgery alone or associated with RT, CT) for the intra-abdominal tumor.
microRNA-27a-3p down-regulation inhibits malignant biological behaviors of ovarian cancer by targeting BTG1
Authors: Li Enfang , Han Ke , Zhou Xuan 
Published: August 2019

Abstract
Ovarian cancer is the most deadly malignant tumor. MicroRNA-27a-3p (miR-27a-3p) was a tumor oncogene in various cancers. However, the role and mechanism of miR-27a-3p in ovarian cancer are still unknown. In this study, we found that miR-27a-3p over-expression could significantly promote the viability of SK-OV-3 cells, enhance cell migration and invasion, and reduce cell apoptosis. Besides, results from western blot assay showed that miR-27a-3p over-expression could increase Bcl-2 protein expression and decrease Bax protein expression. Furthermore, TargetScan and the dual luciferase reporter gene assay revealed that BTG anti-proliferation factor 1 (BTG1) was a direct target of miR-27a-3p. In addition, we found that miR-27a-3p down-regulation suppressed SK-OV-3 cell viability, migration and invasion, and promoted cell apoptosis. All the effects of miR-27a-3p down-regulation on SK-OV-3 cells were reversed by BTG1-siRNA. Therefore, miR-27a-3p/BTG1 axis may be a new potential target for the treatment of ovarian cancer.
CNS myeloid cell heterogeneity at the single-cell level
Authors: Böttcher Chotima , Sankowski Roman , Priller Josef , Prinz Marco 
Published: August 2019

Abstract
The cellular composition of the central nervous system (CNS) is highly complex and dynamic. Regulation of this complexity is increasingly recognized to be spatially and temporally dependent during development, homeostasis and disease. Context-dependent cellular heterogeneity was shown for neuroectodermal cells as well as the myeloid compartment of the CNS. The brain myeloid compartment comprises microglia and other CNS-associated macrophages. These are brain-resident cells with critical roles in brain development, maintenance, and immune responses during states of disease. Profiling of CNS myeloid cell heterogeneity has been greatly facilitated in the past years by development of high-throughput technologies for single-cell analysis. This review summarizes current insights into heterogeneity of the CNS myeloid cell population determined by single-cell RNA sequencing and mass cytometry. The results offer invaluable insights into CNS biology and will facilitate the development of therapies for neurodegenerative and neuroinflammatory pathologies.