bluuebunny/crossref_metadata_2025_split huggingface dataset:
n. 208 (18): Dor On Line
Authors: Barboni Paulo 
Published: October 2018

Caros leitores do nosso boletim, saudações! Nesta edição de novembro de 2017 trazemos mais um editorial de nossa série que trata de quimiocinas e dor, tratando da quimiocina CXCL13. Além disso, trazemos alertas de divulgação científica tratando de problemas clínicos de neuropatia em neonatos devido ao uso de quimioterapia do câncer e o uso de radioterapia para o tratamento da dor em metástases ósseas; personalização gênica de tratamento da dor crônica; atualização de terminologia da dor pela IASP; um estudo de revisão sobre o poder analgésico de bebidas alcoólicas. Nossos alertas de Ciência e Tecnologia tratam da função de RNA não-codificante na dor neuropática; ação do tramadol na dor articular odontológica em modelos experimentais; um novo biofármaco para o tratamento da enxaqueca; o uso de realidade virtual na dor de membro fantasma e o efeito de mudanças hormonais no efeito da endomorfina 2. Boa leitura!
EDITORIAL DO MÊS
Sessão IV - CXCL13: uma quimiocina que estamos começando a conhecer
Andreza Urba Quadros
Divulgação Científica
1.Exposição precoce à Vincristina e alodínia mecânica. Relação entre quimioterapia e neuropatia periférica em neonatos
Paola Costa Carvalho
2. Farmacoeconomia de tratamento baseado em genotipagem em pacientes com dor crônica. A genotipagem pode otimizar os custos na dor crônica
Erika Ivanna Araya Pallarés
3. Nova terminologia de dor da IASP. Dor nociceptiva alterada recebe denominação própria
Francisco Fábio Bezerra de Oliveira
4. Dois copos de cerveja podem aliviar a dor tanto quando o paracetamol. O uso moderado de cerveja auxilia o controle da dor
Dênis Augusto Santana dos Reis
5. Radioterapia é efetiva para o tratamento da dor em pacientes com metástases ósseas. Ensaio clínico com pacientes demonstra controle da dor após radioterapia
Larissa Garcia Pinto
Ciência e Tecnologia
6. RNA longo não-codificante é um novo regulador da dor neuropática em ratos. Inibição de RNA não-codificante como uma possível terapia para dor neuropática
Adriele Alves Santos
7. Efeito anti-inflamatório do tramadol na junção temporomandibular de ratos. Administração intra-articular na dor temporomandibular
Alexandre Maganin
8. Anticorpo anti-CGRP pode ser a nova opção terapêutica para o tratamento da enxaqueca e de dores de cabeça severas. Galcanezumab esta em estudos clínicos de fase III em pacientes
Larissa Garcia Pinto
9. Os benefícios da realidade virtual para pacientes com dor neuropática. A realidade virtual reduz a dor de membros em pacientes paraplégicos e cria a ilusão de que eles podem sentir suas pernas novamente
Alexandre Hashimoto Pereira Lopes
10. Estrogênios inibem a antinocicepção da endomorfina 2 a depender do ciclo reprodutivo de ratas. Hormônio pode bloquear ação de analgésicos endógenos
Ana Carolina Alves M. de Moura
n. 209 (18): Dor On Line
Authors: Barboni Paulo 
Published: October 2018

Olá, leitores do Boletim Dor On Line! Neste mês trazemos mais um editorial da série de quimiocinas, tratando neste mês da CCL2. Temos, também, alertas tratando do estudo da dor. Estes alertas foram apresentados no Congresso Científico Anual da Sociedade Americana de Dor, que aconteceu em maio de 2017, em Pittsburg, EUA. Boa Leitura!
EDITORIAL DO MÊS
Editorial do mês
Sessão V – CCL2
Thayna Moreira Gomes Marra
Divulgação Científica
1. Os efeitos da raça e sexo na hiperalgesia induzida por interrupção experimental do sono
Cássia Regina da Silva
2. Inibição da via de sinalização da proteína Ouriço Sonic (Sonic Hedgehog) previne a tolerância
Rangel Leal Silva
3. Kinesio tape para redução da dor: mais do que um efeito placebo?
Francisco Fábio Bezerra
4. Neuralgia do trigêmeo: Farmacoterapia e tratamento cirúrgico padrão nos Estados Unidos
Erika Ivanna Araya Pallarés
Ciência e Tecnologia
5. Ansiedade e desempenho relacionados à dor medidos por um programa interdisciplinar
Alexandre Hashimoto Pereira Lopes
6. Tratamento intratecal com opioides na dor crônica refratária associada à esclerose mesentérica
Alexandre Gomes de Macedo Maganin
7. Identificando potenciais pacientes com fibromialgia: um novo plano de triagem e diagnóstico usando dados do mundo real
Ieda Regina dos Santos
8. A citocina IL-27 protege o desenvolvimento de dor neuropática por meio do aumento da expressão da proteína anti-inflamatória IL-10
Miriam das Dores Mendes Fonseca
n. 210 (18): Dor On Line
Authors: Barboni Paulo 
Published: October 2018

Feliz 2018 da equipe DOL a todos os nossos leitores do boletim Dor On Line. Este mês trazemos um editorial de nossa série de quimiocinas e dor tratando da CCL7. Além disso, trazemos alertas sobre trabalhos envolvendo o estudo da dor que foram apresentados no 49° Congresso Brasileiro de Farmacologia e Terapêutica Experimental, que ocorreu em Ribeirão Preto em outubro de 2017.

EDITORIAL DO MÊS
Editorial do mês
Sessão VI - CCL7: uma das engrenagens para dor neuropática
Adriele Alves Santos
Ana Carolina Alves Melo de Moura
Giovanna Oliveira de Brito
Divulgação Científica - Trabalhos apresentados no "49th Brazilian Congress of Pharmacology and Experimental Therapeutics", realizado em Ribeirão Preto, São Paulo, Brasil, de 17 a 20 de outubro de 2017.
1. Estrutura análoga ao eugenol exibe atividade antinociceptiva em camundongos
Adriele Alves Santos
2. O tratamento agudo com o agonista do receptor A3 de adenosina altera a resposta hiperalgésica em ratos com dor inflamatória crônica
Adriele Alves Santos
3. Efeito benéfico do lodenafil e do sildenafil na redução de sinais de dor neuropática em ratos submetidos à ligação do nervo espinal
Lilian Thaís Veras de Carvalho
4. Participação do TNF-α e astrócitos na dor induzida pelo tumor de Ehrlich em camundongos
Mariane Aparecida da Silva Marques
5. Envolvimento de citosinas na síndrome de dor aguda induzida pelo Paclitaxel em camundongos
Mariane Aparecida da Silva Marques
6. Interação entre o sulfeto de hidrogênio (H2S) e as diferentes espécies redox de óxido nítrico (NO) - Efeitos na nocicepção e inflamação na articulação temporomandibular do rato (TMJ)
Mariane Aparecida da Silva Marques
7. Relação periférica e central da proteína C5a e seu receptor com a dor neuropática
Ana Carolina Alves Melo de Moura
8. Diabetes leva a hiponocicepção com a inibição Na+ / K+ / ATPase
Ana Carolina Alves Melo de Moura
Giovanna Oliveira Brito
9. Efeito antinociceptivo do aripiprazol por ativação das vias PI3K / AKT / NO / KATP
Thatiane Sandielen Lima Soares
10. A hiperalgesia induzida por artrite na articulação temporomandibular de ratos ativa células microgliais do subnúcleo caudal trigeminal
Thatiane Sandielen Lima Soares
11. Mecanismos envolvidos nos efeitos antinociceptivos e anti-inflamatórios de dihidro-obovatina em um modelo pré-clínico de dor nas articulações temporomandibulares
Giovanna Oliveira de Brito
12. Pesquisa adicional de mecanismos antinociceptivos e pronociceptivos de Acmella oleracea em camundongos
Letícia Menezes Rodrigues
13. Efeitos analgésicos da cetamina intranasal em modelos de ratos de dor orofacial
Thaise Loyanne Felix Dias
14. Nicorandil inibe alodinia mecânica em modelo de dor neuropática induzida por paclitaxel pela ativação dos mecanismos opioidérgicos e serotoninérgicos
Thaise Loyanne Felix Dias
15. O papel das células CCR2 + e CX3CR1 + na gênese e manutenção da dor neuropática
Thaise Loyanne Felix Dias
n. 212 (18): Dor On Line
Authors: Barboni Paulo 
Published: October 2018

Prezados leitores, temos neste mês um editorial sobre a Fractalcina, mais uma quimiocina para a nossa série de editoriais sobre estas biomoléculas. Na seção de Divulgação Científica, temos alertas sobre o uso medicinal da cannabis; efeitos adversos do ibuprofeno; novas tecnologias para o tratamento da dor; o mecanismo de ação do paracetamol; e a saúde mental de adolescentes e o uso de opioides. Na seção de Ciência e Tecnologia, temos alertas tratando da analgesia gestacional; expressões gênicas diferentes e dor neuropática; o papel de receptores muscarínicos na polineuropatia diabética periférica; e células da glia na dor persistente. Boa leitura!
EDITORIAL DO MÊS
Editorial do mês
Sessão VIII – Fractalcina/CX3CL1: um alvo terapêutico no tratamento da dor crônica
Alexandre Hashimoto Pereira Lopes

Divulgação Científica
1. Cannabis como substituto a opioides para tratamento da dor. Pacientes relatam o possível efeito benéfico da cannabis
Mariane Aparecida da Silva
2. A fisiologia testicular frente ao uso do ibuprofeno. Um estado de hipogonodismo compensado
Ana Carolina Alves M. de Moura
3. Tratamento da dor crônica por aromaterapia com hortelã. Engenharia celular a serviço da medicina
Cássia Regina da Silva
4. Acetaminofeno alivia a dor em medula ventromedial rostral. A analgesia conta com a contribuição do sistema canabinoides
Letícia Menezes Rodrigues
5. Condições de saúde mental e tratamentos com opioides analgésicos. O uso de opioides por adolescentes com alguma condição de saúde mental
Giovanna OIiveira de Brito
6. Mediação da analgesia gestacional na dor crônica por células T em camundongos. Mediação importante em modelos de dor crônica inflamatória e neuropática
Isaac Fernandes
7. Diferenças em dor neuropática e a correlação comportamental. Diferenças mecânicas em dor neuropática e a correlação comportamental com perfil de expressão global
Thaise Loyanne Felix Dias
8. Papel dos receptores muscarínicos na neuroproteção durante a neuropatia periférica. Uma opção perto de nós
Andreza Urba de Quadros
9. A importância das células da glia na dor persistente. Por que ainda não temos um medicamento para tratar pacientes com dores crônicas com alvo nas células da glia?
Larissa Garcia Pinto
СТРАТЕГИЧЕСКИЕ ОРИЕНТИРЫ ЭКОНОМИЧЕСКОГО РАЗВИТИЯ РЕСПУБЛИКИ УЗБЕКИСТАН
Authors: Зиядуллаев Улугбек Саидкаримович , Симонова Юлия Сергеевна 
Published: October 2018

МЕЖДУНАРОДНАЯ НАУЧНО-ПРАКТИЧЕСКАЯ КОНФЕРЕНЦИЯ
«СТРАТЕГИЯ ДЕЙСТВИЙ РЕСПУБЛИКИ УЗБЕКИСТАН: МАКРОЭКОНОМИЧЕСКАЯ СТАБИЛЬНОСТЬ, ИНВЕСТИЦИОННАЯ АКТИВНОСТЬ И ПЕРСПЕКТИВЫ ИННОВАЦИОННОГО РАЗВИТИЯ»

РЕСПУБЛИКА УЗБЕКИСТАН,
Г. ТАШКЕНТ, 28–29 МАЯ 2018 Г.
МАКРОЭКОНОМИЧЕСКИЕ ЭФФЕКТЫ ПРЯМОГО ИНОСТРАННОГО ИНВЕСТИРОВАНИЯ В РОССИЙСКУЮ ФЕДЕРАЦИЮ
Authors: Матраева Лилия Валериевна , Алябьева Анастасия Викторовна 
Published: October 2018

Цель работы. Целью работы является исследование макроэкономических эффектов прямого иностранного инвестирования в регионы РФ. Метод или методология проведения работы. Исследование основывается на общенаучной методологии, которая предусматривает применение системного подхода к решению проблем. Основой данной работы являются фундаментальные труды отечественных и зарубежных ученых по проблемам прямого иностранного инвестирования в регионы Российской Федерации. Также в работе используются специальные экономико-статистические методы моделирования макроэкономических процессов, такие как модель мультипликатора-акселератора и модель оценки эффекта мультипликации иностранных инвестиций посредством коэффициентов эластичности. Результаты. С 2003 по 2016 год в РФ приростная капиталоотдача иностранных инвестиций была выше национальных в несколько раз, однако иностранные инвестиции способствовали экономическому росту в России в целом лишь в период с 1999 по 2003 год. Выявленное противоречие объясняется сложившейся дифференциацией потоков и различным влиянием прямых иностранных инвестиций на экономический рост различных регионов РФ. Область применения результатов. Полученные результаты исследования способствуют повышению объективности принятия управленческих решений в отношении стимулирования прямых иностранных инвестиций на общегосударственном уровне с учетом фазы жизненного цикла инвестиционного процесса и характера проявления описанных эффектов от ПИИ на территории РФ. Выводы. В сложившейся ситуации, на наш взгляд, более эффективной становится модель адресной региональной государственной политики стимулирования иностранных инвестиций, которая позволит максимально использовать положительный эффект в конкретных регионах РФ с учетом стадии жизненного цикла иностранных инвестиций в рамках данной территории и нивелировать отрицательные эффекты, наблюдающиеся в других регионах.
Kesempurnaan Wong Menak dalam Wayang Sasak
Authors: Qodri Muh. Syahrul 
Published: October 2018

AbstractThe problem discussed in this article is the values of perfection in the main character of Jayengrana in Wong Menak story of Wayang Sasak in its relation to other figures in the puppet. To explore this issue, the analysis method used is Roland Barthes’ semiotic perspective. Data were collected from interviews and literature study. After applying the stages of semiotic analysis, which is based on 5 codes of Roland Barthes’ semiotics (i. e. hermeneutic, connotation, symbolic, proaretic, and cultural codes), it can be concluded that the perfection of Wong Menak story lies on the glory of himself as wong menak as represented through the his nicknames which prevails on every journey of life. This is because of his ability to manage the five characters that exist in companions and manifest themselves in wong menak itself. Keywords: perfection, wong menak, puppet sasak. AbstrakMasalah yang dibahas dalam artikel ini adalah tentang nilai kesempurnaan yang dimiliki oleh tokoh utama Jayengrana dalam Wong Menak di dalam Wayang Sasak yang dikaitkan dengan tokoh-tokoh lainnya dalam wayang tersebut. Untuk mengupas persoalan tersebut, metode analisis yang digunakan adalah semiotika perspektif Roland Barthes. Data yang dianalisis adalah data dari hasil wawancara dan studi pustaka. Setelah melewati tahapan analisis semiotika yang berlandaskan pada lima kode Roland Barthes (yaitu kode hermeneutik, konotatif, simbolik, proaretik, dan kode kultural), dapat ditarik sebuah kesimpulan bahwa kesempurnaan Wong Menak terletak pada kejayaan dirinya sebagai wong menak yang direpresentasikan lewat nama-nama julukan yang disandangnya, sehingga senantiasa berjaya pada setiap perjalanan kehidupannya. Hal ini disebabkan oleh kemampuannya mengelola kelima karakter yang ada pada diri sahabat-sahabatnya dan menyatu dalam diri wong menak itu sendiri. Kata kunci: kesempurnaan, wong menak, wayang sasak
ANALISIS TINGKAT KERENTANAN MASYARAKAT PETANI PASCA TSUNAMI DI ACEH
Authors: Adhiana Adhiana 
Published: October 2018

This research was conducted in five districts in the province of Aceh, West Aceh district of Aceh Besar, Aceh Pidie, Bireuen, and North Aceh. The total sample for this study was 280 farmers using stratified random sampling method. This research using primary and secondary data. The main objective of this research is to analyze the factors that determine the level of vulnerability of famers communities in Aceh after the tsunami. The analysis model used is the logistic regression model using Maximum Likelihood (MLE).The results found that the finding on logistic regression analysis model showed the vulnerability of farmers affected by the six variables, are the availability of jobs, other job skills, debt, training / courses, savings and family relations. Three other factors are the loss of property, injury and loss of boundaries of the land is not significant. Among the policy implications of the proposed in this study is the increasing human assets, and strengthen the financial assets of farmers
Uneven Development and Non-Western Modernities: A Historical Sociology Guide to the New Turkey
Authors: Göksel Oğuzhan 
Published: October 2018

The term “New Turkey” refers to the ongoing formation of a new socio-political system by the incumbent AKP (Justice and Development Party) administration. A neglected issue within the existing literature is the study of New Turkey in the broad context of social theory beyond Turkish studies. Deterministic narratives of globalization have long presented Turkey as a “beacon of hope” in the Muslim world, a westernizing society that would supposedly combine liberal democracy, Islamic values, secularism and free-market capitalism. In contrast to these expectations, today the New Turkey constitutes an illiberal polity, a neoliberal economy based on clientelism and an increasingly Islamized social environment. How and why the Turkish modernization experience has gradually culminated in an authoritarian non-Western variant of modernity? This article utilizes a historical sociology approach based on the Uneven and Combined Development Theory (U&CD) to locate the origins of the unexpected rise of New Turkey in our age. It is argued that complex interactions between elements of Western modernity (e.g. secularization and democratization), various social engineering programs launched since the late Ottoman era and Turkey’s own path dependent trajectory have gradually produced a socio-economic and political model that radically diverges from the Western experience.
ANALYSIS OF MONITORING STUDIES ON AFRICAN SWINE FEVER VIRUS DNA DETECTION CARRIED OUT IN 2017
Authors: Fedoseyeva D. N. , Aronova Ye. V. , Varentsova A. A. , Yelsukova A. A. , Mazloum Ali , Sharypova D. V. , Vlasova N. N. , Igolkin A. S. 
Published: October 2018

The paper describes the results of testing of biomaterial from domestic pigs and wild boars by real-time PCR used for African swine fever virus genome detection, carried out in the FGBI “Federal Centre for Animal Health” (Vladimir). In 2017 8,500 samples from 44 subjects of the Russian Federation were tested within the framework of the state laboratory monitoring. African swine fever virus genome was detected in 504 samples. In 2017 ASF outbreaks were registered in the Urals and Siberian Federal Districts of the RF for the first time. The conducted research and persistent ASF infection in the territory of the RF have demonstrated the need for further surveillance in the populations of susceptible animals. Development, organization and implementation of the program for ASF spread surveillance in wild fauna remains a high priority. It is necessary to create and implement sampling schedules with uniform sampling of biomaterial and submission of the collected samples to the research laboratories for timely ASF outbreak containment at the regional level.
ANTIBIOTIC RESISTANCE OF ACTINOBACILLUS PLEUROPNEUMONIAE IN SWINE: PROBLEMS AND SOLUTIONS
Authors: Rusaleyev V. S. 
Published: October 2018

Porcine pleuropneumonia is an infectious contagious disease caused by bacteria Actinobacillus pleuropneumoniae. Currently, the disease is widespread in many countries with well-developed pig production. The disease causes significant economic damage to farms due to the large mortality and expenses for treatment of diseased pigs and implementation of veterinary and sanitary measures. Due to increased number of Actinobacillus pleuropneumoniae cases in pigs, and the emergence of actinobacillus-resistant forms, it is necessary to perform a more thorough study and discussion of this problem. The disease epidemic surveillance is based on continuous monitoring aimed at porcine Actinobacillus pleuropneumoniae identification, confirmation and registration, determination of its characteristics and trends in development of sensitivity to antimicrobial preparations. The article addresses the topic of antibiotic use and the antibiotic resistance of microorganisms, which is actual not only for veterinary medicine but also for medicine. The model of swine Actinobacillus pleuropneumoniae was used to study the reasons of antibiotic resistance. Possible approaches to overcoming the resistance of actinobacilli to antibiotics have been discussed. The prospects for the use of antibiotics were discussed in detail to cope with this problem. Targeted surveillance, aimed at monitoring and collecting information on the prescription of antibiotics is of great importance for the solution of the problem of antibiotic resistance. The information obtained from the monitoring can be used for development of the plan and strategy for the use of antibacterial preparations (preparation selection, dose, route of administration, frequency, number of courses), development and implementation of more effective approaches to the treatment of Actinobacillus pleuropneumoniae in pigs, control of the antibiotic-resistant bacteria occurrence and spread.
EFFECT OF p30 RECOMBINANT PROTEIN ON AFRICAN SWINE FEVER VIRUS IN VITRO REPRODUCTION
Authors: Mazloum Ali , Zhukov I. Yu. , Pershin A. S. , Igolkin A. S. , Vlasova N. N. 
Published: October 2018

African swine fever specific prevention means have not been developed yet. However, it is necessary to study the function of definite viral proteins, their role in immune response morphogenesis and induction to determine the components to be included into ASF protection drugs. It was established that p54 and p30 proteins participate in virus penetration and internalization and are able to induce protective antibodies in immunized pigs. The inoculation of these proteins into ASFV-infected cell culture has an impact on virus reproduction to different extents. The results of the study of purified recombinant protein p30 effect, derived from E. coli clone, containing pET32b(+)/р30 plasmid, on ASFV in vitro reproduction are presented. The greatest decrease, including complete inhibition of virus reproduction, was observed when 300 ng of p30 were inoculated into porcine spleen and marrow primary cell cultures, infected with the ASFV Krasnodar 07/17 isolate at the dose of 100 HAU per plate (~ 0.01 HAU per cell). It was noted that if the mixture of p30 and p54 was inoculated into a sample, the virus reproduction was greater compared to the use of only p30.
RESULTS OF EXPERIMENTAL INFECTION OF TURKEYS WITH A/DUCK/ALTAI/469/14 H5N1 STRAIN OF AVIAN INFLUENZA VIRUS
Authors: Sosipatorova V. Yu. , Altunin D. A. , Chvala I. A. , Mudrak N. S. , Andreychuk D. B. 
Published: October 2018

The data on experimental infection of 6-week-old Big-6 cross turkeys with an epidemic A/duck/Altai/469/14 H5N1 clade 2.3.2.1c strain of avian influenza virus are presented. The characteristics of the infection process in birds inoculated intranasally at a dose of 5.0 lg EID50/0.5 cm3 are described with an indication of the incubation period and the mean time of death. The pathomorphological changes at the tissue and cellular level are shown based on histological and immunohistochemical studies of fragments of respiratory, digestive, cardiovascular, nervous, excretory, lymphoid and muscular systems of experimental birds. The testing was carried out using paired preparations of paraffin-embedded tissue sections from experimentally infected and healthy turkeys. One sample was subjected to histological staining using hematoxylin and eosin dyes, and its duplicate was subjected to immunohistochemical assay using a preparation of polyclonal antibodies as primary antibodies against the ribonucleoprotein of avian influenza virus. The results of histological and immunohistochemical studies are photodocumented and presented in the paper. Inflammatory and necrotic lesions of varying severity are detected in the preparations of the trachea, lung, muscular stomach, glandular stomach, small intestine, large intestine, pancreas, brain, cerebellum, heart, kidneys, liver and spleen of turkeys. Immunohistochemical analysis showed the greatest distribution of the influenza virus antigen in the cerebral endothelium, cerebellar Purkinje neurons, acinar cells of the pancreas and in myocardiocytes of the heart. In the course of the experiment it was established that A/duck/Altai/469/14 H5N1 caused a generalized form of infection in turkeys with clinical and pathologic lesions characteristic of highly pathogenic avian influenza.