bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementing a guideline for acute tonsillitis using an ambulatory medical unit
Authors: Perkins C , Ray Brown F , Pohl K , McLaren O , Powles J , Thorley R 
Published: April 2019

AbstractObjectiveAcute tonsillitis represents a significant proportion of admissions to ENT departments nationally. Given current hospital pressures, it is vital to look for safe alternatives to admission. This study explores the safe management of patients in an ambulatory medical unit, without the need for admission.MethodsA retrospective review of 48 patients’ notes was carried out. Following the development and implementation of a guideline for acute tonsillitis, a prospective re-audit of 41 patients was carried out, measuring length of stay, overnight admissions and re-admissions.ResultsThe rate of overnight admission following implementation of the guideline fell from 0.75 to 0.29, and average length of stay dropped from 19.2 to 9.5 hours. There were two re-admissions in each cycle of the audit, which represents a non-significant increase.ConclusionThe tonsillitis guideline has significantly reduced admissions and length of stay. Re-admissions remain low, demonstrating that this is a safe and cost-effective intervention.
Human papillomavirus 16 and p16 positive nasal cutaneous squamous cell carcinoma in immunocompetent men in their twenties
Authors: Amiraraghi N , Scott R A , Balaji N , Yaneza M M C 
Published: April 2019

AbstractBackgroundCutaneous squamous cell carcinoma is usually associated with long-term ultraviolet light exposure. Human papillomavirus 16 is a high-risk mucosal human papillomavirus type, usually associated with anogenital and oropharyngeal cancer. This paper describes the first two cases of human papillomavirus 16 and p16 related nasal cutaneous squamous cell carcinoma.MethodProspective case series from December 2015.ResultsTwo young, male, fair-skinned patients had large (greater than 20 mm), rapidly growing, ulcerated lesions of the nasal tip. The tumours were excised, with at least a 6 mm margin, and the patients' noses were subsequently reconstructed. Neither patient had cervical lymphadenopathy or underwent adjuvant radiotherapy. Both patients were registered at the same general practice. The tumours were human papillomavirus 16 and p16 positive; the latter indicated that the virus was driving the disease process. Except for superficial burns, neither patient had other risk factors.ConclusionChanges in sexual practices have led to an increase in human papillomavirus positive oropharyngeal carcinoma and there may be an associated increase in human papillomavirus type 16 positive nasal cutaneous squamous cell carcinoma.
Widowhood and mortality risk of older people in rural China: do gender and living arrangement make a difference?
Authors: Liu Huijun , Jiang Quanbao , Feldman Marcus W. 
Published: April 2019

AbstractIncreased mortality after spousal bereavement has been observed in many populations. Few studies have investigated the widowhood effect in a traditional culture where the economy is underdeveloped. The reasons for the widowhood effect and its gender dynamic are not well understood. In this study, we assessed whether the widowhood-associated excess mortality exists and differs by gender and living arrangement in rural China. We used a six-wave panel of data derived from rural people over 60 years old in the Chaohu region of China. Cox regression analyses suggest that there was a positive effect of spousal loss on mortality for older rural Chinese and this effect was gender different. Our findings also suggest that living with adult children after spousal loss played a protective role in reducing the risk of older men's death, though it tended to increase older men's mortality risk in general.
EFFECTS OF NARROW READING AND LISTENING ON L2 VOCABULARY LEARNING
Authors: Chang Anna C-S. 
Published: April 2019

AbstractSixty target words were selected from two sets of graded readers. One set contained three readers with the same title,The Railway Children, and the other set, three books about Sherlock Holmes. Students chose one of the two sets to read and were given a pretest, an immediate posttest, and a five-week delayed posttest on their acquisition of spelling, aural meaning, written meaning, and use. Five fixed factors (time, frequency of word occurrence, glossing, word frequency levels, and four dimensions of vocabulary knowledge) in vocabulary learning and a random variable (the participants) were analyzed with generalized linear mixed models. The results show that the odds of improvements in the knowledge of written and aural meanings were significantly better than those for the knowledge of spelling and use. Significant interaction effects were found between time and other fixed factors, except for glossing. Pedagogical implications of the results are discussed.
Enhancing Equitable Access to Assistive Technologies in Canada: Insights from Citizens and Stakeholders
Authors: Mattison Cristina A. , Wilson Michael G. , Wang Rosalie H. , Waddell Kerry 
Published: April 2019

RÉSUMÉLes besoins en technologies d’assistance augmentent au Canada, mais l’accès à ces technologies est inégal et fragmentaire, ce qui ferait en sorte que des besoins demeureraient non comblés. Cette étude visait à identifier les valeurs et préférences des citoyens concernant les moyens à utiliser pour favoriser un accès équitable aux technologies d’assistance. Elle visait également à impliquer les décideurs politiques, les parties prenantes et les chercheurs dans des discussions afin d’élaborer des actions dans ce domaine. Au printemps 2017, nous avons organisé trois panels de citoyens et un dialogue avec les parties prenantes. Les principales conclusions des panels ont été incluses dans une synthèse qui a été partagée avec les participants du dialogue. Trente-sept citoyens ont participé aux panels et ont souligné l’importance de l’accès à de l’information fiable, d’un accès équitable aux technologies d’assistance (et ce, quelle que soit la capacité de payer), et de la collaboration. Les vingt-deux participants au dialogue ont fait valoir la nécessité d’un cadre d’orientation pour appuyer l’évolution des pratiques dans l’ensemble au pays. Le cadre d’orientation proposé combinerait des politiques et programmes simplifiés incluant la collecte et l’évaluation de données robustes pour appuyer l’innovation et l’imputabilité à travers le pays.
Practical Ethics Given Moral Uncertainty
Authors: MacAskill William 
Published: April 2019

AbstractA number of philosophers have claimed that we should take not just empirical uncertainty but also fundamental moral uncertainty into account in our decision-making, and that, despite widespread moral disagreement, doing so would allow us to draw robust lessons for some issues in practical ethics. In this article, I argue that, so far, the implications for practical ethics have been drawn too simplistically. First, the implications of moral uncertainty for normative ethics are far more wide-ranging than has been noted so far. Second, one can't straightforwardly argue from moral uncertainty to particular conclusions in practical ethics, both because of ‘interaction’ effects between moral issues, and because of the variety of different possible intertheoretic comparisons that one can reasonably endorse.
Decidability of regular language genus computation
Authors: Bonfante Guillaume , Deloup Florian L. 
Published: April 2019

AbstractThis article continues the study of the genus of regular languages that the authors introduced in a 2013 paper (published in 2018). In order to understand further the genus g(L) of a regular language L, we introduce the genus size of |L|gen to be the minimal size of all finite deterministic automata of genus g(L) computing L.We show that the minimal finite deterministic automaton of a regular language can be arbitrarily far away from a finite deterministic automaton realizing the minimal genus and computing the same language, in terms of both the difference of genera and the difference in size. In particular, we show that the genus size |L|gen can grow at least exponentially in size |L|. We conjecture, however, the genus of every regular language to be computable. This conjecture implies in particular that the planarity of a regular language is decidable, a question asked in 1976 by R. V. Book and A. K. Chandra. We prove here the conjecture for a fairly generic class of regular languages having no short cycles. The methods developed for the proof are used to produce new genus-based hierarchies of regular languages and in particular, we show a new family of regular languages on a two-letter alphabet having arbitrary high genus.
Transcatheter closure of doubly committed subarterial ventricular septal defects with the Amplatzer ductal occluder: initial experience
Authors: Huang Yu , Yan Xiaoping , Lu Linxiang , Fang Jun , Sun Xudong , Zhong Ling , Li Jinguo , Chen Lianglong 
Published: April 2019

AbstractBackground:There is limited experience about transcatheter closure of doubly committed subarterial ventricular septal defects with Amplatzer ductal occluder.Methods:Between March, 2015 and July, 2017, a total of 22 patients with doubly committed subarterial ventricular septal defects received transcatheter closure using Amplatzer ductal occluder and underwent clinical follow-up for at least 6 months.Results:Device implantation was finally successful in 21 (95.4%) patients despite failed occlusion in one patient and intra-procedural replacement of unsuitable occluders in four (19.0%) patients. In mean 12.3 months of follow-up, there were no major complications (death, aortic valve or sinus rupture, device dislocation or embolisation, grade 2 new-onset aortic regurgitation, etc.), resulting in clinical occlusion success of 95.4%. Mechanical haemolysis occurred in one patient and resolved with medication. Residual shunt was observed in 11 (52.4%) patients (9 mild, 2 moderate-severe) post-procedurally, 14 (66.7%) patients (12 mild, 2 moderate-severe) in hospital stay, and 2 (9.5%) patients (2 mild, 0 moderate-severe) at the last follow-up. Device-induced new-onset aortic regurgitation was found in nine (42.8%) patients (9 mild, 0 moderate-severe) post-procedurally and in hospital stay, which was resolved in two (9.5%) patients and unchanged in seven (33.3%) patients at the last follow-up. Another four (19.0%) patients newly developed mild aortic regurgitation during follow-up.Conclusions:Transcatheter closure of doubly committed subarterial ventricular septal defects with Amplatzer ductal occluder is technically feasible in the selected patients. However, further study is needed to confirm its long-term clinical outcomes.
A path to the bilingual advantage: Pairwise matching of individuals
Authors: Czapka Sophia , Wotschack Christiane , Klassert Annegret , Festman Julia 
Published: April 2019

AbstractMatching participants (as suggested by Hope, 2015) may be one promising option for research on a potential bilingual advantage in executive functions (EF). In this study we first compared performances in three EF-tasks of a naturally heterogeneous sample of monolingual (n = 69, age = 9.0 y) and multilingual children (n = 57, age = 9.3 y). Secondly, we meticulously matched participants pairwise to obtain two highly homogeneous groups to rerun our analysis and investigate a potential bilingual advantage. The initally disadvantaged multilinguals (regarding socioeconomic status and German lexicon size) performed worse in updating and response inhibition, but similarly in interference inhibition. This indicates that superior EF compensate for the detrimental effects of the background variables. After matching children pairwise on age, gender, intelligence, socioeconomic status and German lexicon size, performances became similar except for interference inhibition. Here, an advantage for multilinguals in the form of globally reduced reaction times emerged, indicating a bilingual executive processing advantage.
Study of Geometrically Necessary Dislocations of a Partially Recrystallized Aluminum Alloy Using 2D EBSD
Authors: Seyed Salehi Majid , Anjabin Nozar , Kim Hyoung S. 
Published: April 2019

AbstractDuring recrystallization, the growth of fresh grains initiated within a deformed microstructure causes dramatic changes in the dislocation structure and density of a heavily deformed matrix. In this paper, the microstructure of a cold rolled and partially recrystallized Al-Mg alloy (AA5052) was studied via electron backscattered diffraction (EBSD) analysis. The structure and density of the geometrically necessary dislocations (GNDs) were predicted using a combination of continuum mechanics and dislocation theory. Accordingly, the Nye dislocation tensor, which determines the GND structure, was estimated by calculation of the lattice curvature. To do so, five components of the Nye dislocation tensor were directly calculated from the local orientation of surface points of the specimen, which was determined by two-dimensional EBSD. The remaining components of GNDs were determined by minimizing a normalized Hamiltonian equation based on dislocation energy. The results show the elimination of low angle boundaries, lattice curvature, and GNDs in recrystallized regions and the formation of low angle boundaries with orientation discontinuities in deformed grains, which may be due to static recovery.
A high proportion of beta-tocopherol in vitamin E is associated with poor seed longevity in rice produced under temperate conditions
Authors: Lee Jae-Sung , Kwak Jieun , Cho Jun-Hyeon , Chebotarov Dmytro , Yoon Mi-Ra , Lee Jeom-Sig , Hamilton N. Ruaraidh Sackville , Hay Fiona R. 
Published: April 2019

AbstractSeeds of 15 diverse rice accessions, representing aus, indica, temperate japonica and tropical japonica subpopulations, were produced under temperate climate conditions in Korea and used for vitamin E analysis and seed storage experiments at 45°C and 10.9% seed moisture content. High γ-tocotrienol was significantly positively correlated with seed longevity. In addition, a high β-tocopherol proportion relative to δ-tocopherol was significantly negatively correlated with seed longevity. Using high-density single-nucleotide polymorphism marker data, DNA haplotype analysis showed clear allelic variations in the region of two S-adenosylmethionine synthetase genes: LOC_Os04g42095 and LOC_Os11g15410, which regulate the conversion of δ-tocopherol into β-tocopherol. Four indica accessions with rare and subpopulation-specific alleles showed a 2.3-fold lower β-/δ-tocopherol ratio compared with accessions from other subpopulations.
An analysis of the development assistance for health (DAH) allocations for STD control in Africa
Authors: Furuoka Fumitaka , Hoque Mohammad Zahirul , Jacob Ray Ikechukwu , Ziegenhain Patrick 
Published: April 2019

AbstractThe Sustainable Development Goals set by the United Nations recognize the importance of making progress in the eradication and treatment of sexually transmitted deceases (STD). STD are among the most widespread diseases in the world and have the highest prevalence in Sub-Saharan Africa. The current study explored the associations between the allocation of the development assistance for health (DAH) in 54 African countries and key development indicators – STD incidence, Gross Domestic Product per capita, health expenditure, and life expectancy at birth. It employed descriptive statistical methods, the matrix scatter plot analysis and the Pearson correlation test for this purpose. The findings indicated that there was a considerable increase in the volume of the DAH given to control and prevent STD in Africa over the period of 2002–2011. A statistically significant positive association was detected between the STD incidence and the health aid allocations. At the same time, the imbalance in the distribution of the health aid between the major and minor aid recipients in the continent increased. The study concludes by discussing policy implications that can be drawn from these findings.
The relationship between diet, energy balance and fertility in men
Authors: Suliga Edyta , Głuszek Stanisław 
Published: April 2019

Abstract. Research conducted in recent years provides more and more evidence that diet can have a significant impact on male fertility. The aim of the study was to analyze the relationship between diet, energy balance and fertility in men. A comprehensive literature search of published studies in various languages, was carried out in electronic databases. The direct analysis included 96 works published between 2008 and 2018, including 12 randomized controlled trials and 23 systematic reviews and meta-analyses. A strong adherence to a healthy dietary pattern is positively correlated with total sperm count, progressive motility and total motile sperm count (all p < 0.05). However, attention is drawn to the fact that foods that are considered “healthy” can sometimes contain a significant amount of pollution, which negatively affect the semen parameters. An adequate intake of antioxidants or their supplementation have been quite effective in the prevention and treatment of male infertility. The improvement of pregnancy rate after antioxidant therapy ranged in various studies from 11% to 41%. An important problem, however, may be choosing the right dose of the supplement or finding an appropriate combination of antioxidants that may be more effective than any single antioxidant. The normalization of men’s body weight is beneficial for the quality of sperm and the concentration of male reproductive hormones. Further, long-term studies require the assessment of the impact of drastic weight loss after bariatric surgery on male fertility.
Competing Effects of Mountain Uplift and Landslide Erosion Over Earthquake Cycles
Authors: Li Gen , West A. Joshua , Qiu Hongrui 
Published: April 2019

AbstractLarge earthquakes can construct mountainous topography by inducing rock uplift but also erode mountains by causing landslides. Observations following the 2008 Wenchuan earthquake show that landslide volumes in some cases match seismically induced uplift, raising questions about how the actions of individual earthquakes accumulate to build topography. Here we model the two‐dimensional surface displacement field generated over a full earthquake cycle accounting for coseismic deformation, postseismic relaxation, landslide erosion, and erosion‐induced isostatic compensation. We explore the related volume balance across different seismotectonic and topographic conditions and revisit the Wenchuan case in this context. The ratio (Ω) between landslide erosion and uplift is most sensitive to parameters determining landslide volumes (particularly earthquake magnitudeMw, seismic energy source depth, and failure susceptibility, as well as the seismological factor responsible for triggering landslides), and is moderately sensitive to the effective elastic thickness of lithosphere,Te. For a specified magnitude, more erosive events (higher Ω) tend to occur at shallower depth, in thicker‐Telithosphere, and in steeper, more landslide‐prone landscapes. For given landscape and seismotectonic conditions, the volumes of both landslides and uplift to first order positively scale withMwand seismic momentMo. However, higherMwearthquakes generate lower landslide and uplift volumes per unitMo, suggesting lower efficiency in the use of seismic energy to drive topographic change. With our model, we calculate the long‐term average seismic volume balance for the eastern Tibetan region and find that the net topographic effect of earthquakes in this region tends to be constructive rather than erosive. Overall, destructive events are rare when considering processes over the full earthquake cycle, although they are more likely if only considering the coseismic volume budget (as was the case for the 2008 Wenchuan earthquake where landsliding substantially offset coseismic uplift). Irrespective of the net budget, our results suggest that the erosive power of earthquakes plays an important role in mountain belt evolution, including by influencing structures and spatial patterns of deformation, for example affecting the wavelength of topography.
Mechanisms of Ocean Heat Anomalies in the Norwegian Sea
Authors: Asbjørnsen Helene , Årthun Marius , Skagseth Øystein , Eldevik Tor 
Published: April 2019

AbstractOcean heat content in the Norwegian Sea exhibits pronounced variability on interannual to decadal time scales. These ocean heat anomalies are known to influence Arctic sea ice extent, marine ecosystems, and continental climate. It nevertheless remains unknown to what extent such heat anomalies are produced locally within the Norwegian Sea, and to what extent the region is more of a passive receiver of anomalies formed elsewhere. A main practical challenge has been the lack of closed heat budget diagnostics. In order to address this issue, a regional heat budget is calculated for the Norwegian Sea using the ECCOv4 ocean state estimate—a dynamically and kinematically consistent model framework fitted to ocean observations for the period 1992–2015. The depth‐integrated Norwegian Sea heat budget shows that both ocean advection and air‐sea heat fluxes play an active role in the formation of interannual heat content anomalies. A spatial analysis of the individual heat budget terms shows that ocean advection is the primary contributor to heat content variability in the Atlantic domain of the Norwegian Sea. Anomalous heat advection furthermore depends on the strength of the Atlantic water inflow, which is related to large‐scale circulation changes in the subpolar North Atlantic. This result suggests a potential for predicting Norwegian Sea heat content based on upstream conditions. However, local surface forcing (air‐sea heat fluxes and Ekman forcing) within the Norwegian Sea substantially modifies the phase and amplitude of ocean heat anomalies along their poleward pathway, and, hence, acts to limit predictability.
How Will a Warming Climate Affect the Benguela Coastal Low‐Level Wind Jet?
Authors: Lima Daniela C. A. , Soares Pedro M. M. , Semedo Alvaro , Cardoso Rita M. , Cabos William , Sein Dmitry V. 
Published: April 2019

AbstractThe strong coastal upwelling associated to the Benguela eastern boundary upwelling system makes the ocean along coast of this current one of the most productive ecosystems in the world. The Benguela Coastal Low‐Level Jet (BCLLJ) is one of the most important mesoscale feature that shape the climate of this region. The main synoptic forcing of the BCLLJ is the Angola thermal low over land and the St. Helen anticyclone over the ocean, resulting in southwesterly winds along the coast. This study investigates how the BCLLJ might change due to climate warming, with the help of uncoupled and coupled simulations from a 25‐km horizontal resolution regional climate model (ROM). In general, the coupled simulation displays the best performance in representing the present time near‐surface wind speed, with a decrease on the known warm bias of sea surface temperature in the Benguela eastern boundary upwelling system region. The analysis of the projected changes of the BCLLJ climate toward the end of the 21st century (2070–2099), following the RCP8.5 emissions scenario, shows an increase in the frequency of the BCLLJ occurrence along the southern area with higher changes in the coupled simulation (between 6% and 8%). These changes are related to a southerly shift of the St. Helen High, which intensifies the flow offshore the west coast of South Africa and causes a sharpening of the land‐sea thermal contrasts. However, during spring, associated with the decrease in near‐surface wind speed due to higher sea surface temperatures, the future frequency and intensity of the BCLLJ are lower.