bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medicare Part D beneficiaries’ self-reported barriers to switching plans and making plan comparisons at all
Authors: Bruine de Bruin Wändi , Hodson Nathan , Rabinovich Lila , Czarnowske Daniel , Heiss Florian , Winter Joachim , Wuppermann Amelie , McFadden Daniel 
Published: November 2024

Abstract
In the United States, individuals with disabilities and those aged ≥65 can supplement their Medicare with so-called stand-alone Medicare Part D prescription drug plans. Beneficiaries can switch their stand-alone prescription drug plans annually, but most do not. Indirect evidence has raised concerns that non-switchers do not even make plan comparisons (labeled “inattention”), but direct evidence is scarce. Therefore, we surveyed 439 beneficiaries of Medicare Part D plans from a nationally representative adult sample after the 2024 open-enrollment period. Overall, 53% self-reported making no comparisons. Of those who did not compare, 98% did not switch (vs 67% of those who did compare). Multinomial regressions revealed that beneficiaries who neither compared nor switched were more likely than switchers to report difficulties with comparing and switching, experiencing no plan-related discontinuation, changes, or dissatisfaction, not using advisors or the plan-finder website, and receiving potentially confusing mailings. Non-switchers who did compare were similar to switchers in reporting few difficulties and relying on advisors and the plan-finder website, but they were less likely than switchers to report plan-related changes, discontinuation, or dissatisfaction, while being more likely to report receiving mailings and having no college degree. We discuss insights for policy-making.
Risk of cognitive decline among patients with dengue virus infection: a systematic review
Authors: Thangavelu Lakshmi , Abdelwahab Siddig Ibrahim , Farasani Abdullah , Ballal Suhas , Bansal Pooja , Nathiya Deepak , Kaur Kiranjeet , Kumar M Ravi , Sinha Aashna , Alrasheed Hayam A , Al-Subaie Maha F , Al Kaabi Nawal A , bshabshe Ali Al , Al Fares Mona A , Albayat Hawra , Rabaan Ali A , Pant Kumud , Zahiruddin Quazi Syed , Rao Arathi P , Khatib Mahalaqua Nazli , Alfaifi Hassan Ahmad , Mohan Syam , Sah Sanjit , Satapathy Prakasini 
Published: November 2024

Abstract
Dengue fever, caused by the dengue virus and transmitted through Aedes mosquitoes, is a growing public health concern, particularly in tropical and subtropical regions. Traditionally associated with febrile and hemorrhagic symptoms, recent research suggests a potential link between dengue and cognitive impairments. This systematic review assessed existing research to understand the association between dengue virus infection and cognitive impairments, including dementia, Alzheimer disease, memory loss, and confusion. This systematic review followed preferred reporting items for systematic reviews and meta-analyses guidelines. A comprehensive literature search was conducted in PubMed, EMBASE, and Web of Science up to January 18, 2024. Studies examining the prevalence and association of cognitive impairments in dengue patients were included. Data extraction and quality assessment were performed using Nested Knowledge software and the Newcastle-Ottawa Scale. Of the 1129 articles identified, 5 were included in the review, covering a total of 200 873 participants from Taiwan, Brazil, and France. Evidence from population-based cohort studies indicated short-term cognitive impairments, including confusion and memory loss, in some dengue patients. Additionally, long-term risks of dementia, including Alzheimer disease and vascular dementia, were observed, particularly among older adults. Although the findings suggest there might be an association between dengue infection and cognitive decline, the mechanisms underlying this link remain unclear. This systematic review suggests that dengue virus infection may affect cognitive function in both acute and long-term contexts. However, the current evidence is not strong enough to establish a conclusive link. Further research with larger sample sizes and longitudinal studies is essential to confirm the impact of dengue virus on cognitive health.
Music as capitalist icon
Authors: Parkhurst Bryan 
Published: November 2024

ABSTRACT
This paper criticizes interpreters who appeal to structural homologies in making claims about the meaning of (classical instrumental) music. Such appeals are prevalent in Marxist and post-Marxist musical aesthetics, where structural correspondences between music and society are accorded great significance, and their prevalence can be traced to Adorno’s use of (what this paper calls) “semantically ambitious homologies,” which can be traced to Freud’s use of them. I lay out this genealogy and argue that homology-based musical semantics, as it has been customarily practiced, is a nonstarter.
Major histocompatibility complex class II genes allele diversity in landlocked seals
Authors: Meschersky Ilya G , Meschersky Sergey I , Kryukova Natalia V , Solovyeva Maria A , Boltnev Evgeniy A , Klimov Fedor V , Rozhnov Viatcheslav V 
Published: November 2024

Abstract
The allelic diversity of exon 2 (DQB gene) and exon 3 (DRB gene) of major histocompatibility complex class II was studied for the first time in two species of the landlocked pinnipeds, Baikal (N = 79) and Caspian (N = 32) seals, and these were compared with the widespread Arctic species, the ringed seal (N = 13). The analysis of the second exon comprising the antigen-binding region revealed high allelic diversity in all three species, but the pattern of the diversity was the most specific for the Baikal seal. This species differs from the other two by the smallest number of alleles in the population, yet they have the largest number of alleles per individual and by the maximum similarity of individual genotypes. Presumably, this specificity is a consequence of the spatial and temporal homogeneity of the Lake Baikal environment. Analysis of the third exon encoding the conserved β2-domain showed that the Baikal seal differs by the greatest number of amino acid sequences per individual, while the Caspian seal has the lowest number of variants. A single variant of the β2-domain, the same as in the ringed seal, predominates in the Caspian seal, whereas in the Baikal seal the two other variants predominate. At the same time, three species-specific amino acid sequences were observed among minor variants in the Caspian seal, while only one was found in the Baikal seal. This fact may suggest a longer period of independent evolution in the Caspian seal compared to the Baikal seal.
Laparoscopic reoperation of the bile duct in a patient with situs inversus totalis: a case report
Authors: Zhu Shengchang , Luo Liang 
Published: November 2024

Abstract
Situs inversus totalis is a rare congenital anomaly, where the positions of major internal organs are reversed from their normal arrangement. This anatomical abnormality significantly increases the complexity of surgeries, especially in laparoscopic reoperations of the bile duct for patients with a history of abdominal surgery. Traditional anatomical landmarks and surgical steps need to be adjusted according to the patient’s unique anatomy. This not only makes intraoperative identification of structures more challenging but also introduces greater uncertainty during the procedure. This case report summarizes the successful laparoscopic reoperation of the bile duct in a patient with situs inversus totalis, providing important reference and guidance for future similar procedures.
Diagnostic uncertainty and management of low-grade appendiceal mucinous neoplasm—a case report and review of the literature
Authors: Lu Charles , Embel Veysel K , Fox Mackenzie E , Donne Robin , Parker Glenn S 
Published: November 2024

Abstract
Low-grade appendiceal mucinous neoplasm (LAMN) is a rare entity identified in ~1% of patients undergoing appendectomy. The presentation often varies, making diagnosis challenging. Timely identification and treatment are critical to prevent rupture, which may lead to pseudomyxoma peritonei. We describe the case of a 41-year-old male who presented for evaluation of acute right lower quadrant abdominal pain. The clinical impression was consistent with appendicitis with a clinical suspicion for underlying malignancy. The patient was brought to the operating room for an exploratory laparotomy and right hemicolectomy, revealing low-grade appendiceal mucinous neoplasm. The diagnosis of low-grade appendiceal mucinous neoplasm can be challenging given the variable presentation and imaging findings. Early recognition and treatment are imperative to prevent progression to pseudomyxoma peritonei. Our case report seeks to contribute to the ongoing literature and provide a review of the current knowledge.
Host-dependent specialized metabolism of nitrogen export in actinorhizal nodules induced by diazotrophic Actinomycetota Frankia cluster-2
Authors: Berckx Fede , Nguyen Thanh Van , Hilker Rolf , Wibberg Daniel , Battenberg Kai , Kalinowski Jörn , Berry Alison , Pawlowski Katharina 
Published: November 2024

Abstract
Frankia cluster-2 strains are diazotrophs that engage in root nodule symbiosis with actinorhizal plants of the Cucurbitales and the Rosales. Previous studies have shown that an assimilated nitrogen source, presumably arginine, is exported to the host in nodules of Datisca glomerata (Cucurbitales), while a different metabolite is exported in the nodules of Ceanothus thyrsiflorus (Rosales). To investigate if an assimilated nitrogen form is commonly exported to the host by cluster-2 strains, and which metabolite would be exported in Ceanothus, we analysed gene expression levels, metabolite profiles, and enzyme activities in nodules. We conclude that the export of assimilated nitrogen in symbiosis seems to be a common feature for Frankia cluster-2 strains, but the source of nitrogen is host dependent. The export of assimilated ammonium to the host suggests that 2-oxoglutarate is drawn from the tricarboxylic acid (TCA) cycle at a high rate. This specialized metabolism obviates the need for the reductive branch of the TCA cycle. We found that several genes encoding enzymes of central carbon and nitrogen metabolism were lacking in Frankia cluster-2 genomes: the glyoxylate shunt and succinate semialdehyde dehydrogenase. This led to a linearization of the TCA cycle, and we hypothesized that this could explain the low saprotrophic potential of Frankia cluster-2.
SlMIPS2, a myo-inositol phosphate synthase, regulates phosphate homeostasis by influencing SlPHL1 and SlSPX2 levels in tomato seedlings
Authors: Roychowdhury Abhishek , Kaushik Dolly , Bhosale Jayashri Babaji , Srivastava Rajat , Kumar Rahul 
Published: November 2024

Abstract
Phosphorus (P) is an essential macronutrient utilized by plants to support various metabolic processes during growth and development. Recent studies have revealed the pivotal role of inositol hexakis/pyrophosphates (InsP6–8), the derivatives of myo-inositol (MI), in facilitating the interaction between SYG1/PHO81/XPR1 (SPX) and phosphate starvation response (PHR) proteins. myo-Inositol phosphate synthase (MIPS) catalyses the first committed step in MI biosynthesis. Although the role of MIPS genes in mediating stress responses in plants is well elucidated, their role in phosphate (Pi) deficiency remains largely unexplored. This study demonstrates that out of the five MIPS genes encoded by the tomato genome, only SlMIPS2 is sharply induced at an early stage of Pi starvation in tomato seedlings. Silencing of SlMIPS2 led to improved seedling growth with enhanced total soluble Pi and total P levels in silenced plants under high Pi availability. SlMIPS2 silencing also caused a significant reduction in MI and InsP6 content in tomato seedlings. These seedlings with depleted InsP6 levels accumulated lower levels of SlSPX2 protein. In contrast, stabilized SlPHL1 levels were noticed in these plants, directly implicating this transcription factor in activating phosphate-starvation-inducible genes in the SlMIPS2-silenced seedlings, even under high Pi conditions. The results assign a novel role to SlMIPS2 in regulating cellular InsP6 levels and SPX–PHR interactions to control Pi homeostasis in tomato seedlings.
Military Medical Simulations—Scoping Review
Authors: Caffery Sophia J , Ferrari Brock D , Hackett Matthew G 
Published: November 2024

ABSTRACT

Introduction
The military employs a wide variety of training paradigms to prepare a ready medical force. Simulation-based training is prominently used in the military for all roles of care to provide the knowledge, skills, and abilities needed to render care from the battlefield to the hospital. The purpose of this scoping review is to synthesize the body of research in military healthcare simulation, highlight trends in the literature, and identify research gaps.

Materials and Methods
Using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis process, the databases of PubMed, Google Scholar, and targeted conferences were searched for articles focused on simulation-based training in the military healthcare community. Inclusion criteria required that the studies assessed a healthcare simulation intervention and had military participants. Data were gathered on population parameters (branch of service and provider level) as well as study parameter (simulation modality, medical domain, and outcome measures). Outcome measures were categorized according to the Kirkpatrick model of training evaluation.

Results
A total of 43 articles met inclusion criteria. Article summaries and descriptive data on the participant populations and study parameters are provided in Tables 1, 2, and Supplementary Table S1.

Conclusions
Participant populations were inclusive of all the services and roles of care, suggesting appropriate representation of the broad military healthcare community. The majority of literature has studied physical simulations, such as manikins or task trainers. Few studies employed augmented or virtual reality as the training intervention, likely because of the nascency of the technology. Trauma care was the focus of 65% of the studies; this is attributable to the criticality of trauma care within battlefield medicine and casualty response. Related to study outcomes, participant reactions, such as usability and user acceptance, and immediate learning outcomes were heavily studied. Retention and behavioral changes were rarely studied and represent a significant research gap. Future research assessing mixed reality technologies would be beneficial to determine whether the technology warrants inclusion in programs of instruction. Finally, studies with outcome measures including long-term knowledge and skills retention, behavioral change, or patient outcomes are strongly recommended for future research.
The baryon census and the mass-density of stars, neutral gas, and hot gas as a function of halo mass
Authors: Dev Ajay , Driver Simon P , Meyer Martin , Robotham Aaron , Obreschkow Danail , Popesso Paola , Comparat Johan 
Published: November 2024

ABSTRACT
We study the stellar, neutral gas content within haloes over a halo mass range $10^{10} \text{ to } 10^{15.5} \text{M}_\odot$ and hot X-ray gas content over a halo mass range $10^{12.8} \text{ to } 10^{15.5} \text{M}_\odot$ in the local universe. We combine various empirical data sets of stellar, H i, and X-ray observations of galaxies, groups, and clusters to establish fundamental baryonic mass versus halo mass scaling relations. These scaling relations are combined with halo mass function to obtain the baryon densities of stars, neutral gas, and hot gas ($T\gt 10^6 \text{K}$), as a function of halo mass. We calculate the contributions of the individual baryonic components to the cosmic baryon fraction. Cosmic stellar mass density ($\Omega _\text{star}=2.09^{+0.21}_{-0.18} \times 10^{-3}$), cosmic H i mass density ($\Omega _\rm{H\,{\small I}}=0.49^{+0.25}_{-0.12} \times 10^{-3}$), and cosmic neutral gas mass density ($\Omega _\text{neutral gas}=0.71^{+0.39}_{-0.18} \times 10^{-3}$) estimates are consistent with previous more direct method measurements of these values, thereby establishing the veracity of our method. We also give an estimate of the cosmic hot plasma density ($\Omega _\text{hot gas}=2.58^{+2.1}_{-0.66} \times 10^{-3}$).
Stellar stripping efficiencies of satellites in numerical simulations: the effect of resolution, satellite properties, and numerical disruption
Authors: Martin G , Pearce F R , Hatch N A , Contreras-Santos A , Knebe A , Cui W 
Published: November 2024

ABSTRACT
The stellar stripping of satellites in cluster haloes is understood to play an important role in the production of intracluster light. Increasingly, cosmological simulations have been utilized to investigate its origin and assembly. However, such simulations typically model individual galaxies at relatively coarse resolutions, raising concerns about their accuracy. Although there is a growing literature on the importance of numerical resolution for the accurate recovery of the mass-loss rates of dark matter (DM) haloes, there has been no comparable investigation into the numerical resolution required to accurately recover stellar mass-loss rates in galaxy clusters. Using N-body simulations of satellite galaxies orbiting in a cluster halo represented by a static external potential, we conduct a set of convergence tests in order to explore the role of numerical resolution and force softening length on stellar stripping efficiency. We consider a number of orbital configurations, satellite masses, and satellite morphologies. We find that stellar mass resolution is of minor importance relative to DM resolution. Resolving the central regions of satellite DM haloes is critical to accurately recover stellar mass-loss rates. Poorly resolved DM haloes develop cored inner profiles and, if this core is of comparable size to the stellar component of the satellite galaxy, this leads to significant overstripping. To prevent this, relatively high DM mass resolutions of around $M_{\rm DM}\sim 10^{6}$ M$_{\odot }$, better than those achieved by many contemporary cosmological simulations, are necessary.
The Three-Tier Structural Legal Deficit Undermining the Protection of Employees’ Personal Data in the Workplace
Authors: Albin Einat 
Published: November 2024

Abstract
—Even though personal data protection is a fundamental right, and legislation and the courts aim to pursue it, in practice, employees have no meaningful protection of their personal data within the workplace and have few opportunities to act, individually or collectively, to ensure the security of their data. In this article, I argue that a central reason for this state of affairs is the intersection of labour law and personal data protection regulation that creates a three-tier structural legal deficit. The three tiers are: the basic structure of labour law that ensures employer prerogative to use new technologies that are based on datafication almost unlimitedly; the consumer orientation of personal data protection regulation under the General Data Protection Regulation; and lack of specific labour law tools to protect personal data. By building on the structural understanding of the law, and by unravelling the three tiers, the article proposes robust labour law tools to enhance the protection of employees’ personal data.
The role of NGOs and humanitarian organizations in enhancing surgical capacity in Africa: lessons learned and future directions—a narrative review
Authors: Tukur Hajar Nasir , Uwishema Olivier , Soufan Fatima , Tamir Ruth Girum , Wellington Jack 
Published: November 2024

Abstract

Introduction
Significant inequities exist in surgical care accessibility across marginalized African communities. Non-governmental organizations (NGOs) and humanitarian groups are vital in supporting Africa’s surgical infrastructure. This narrative review explores the current status of surgical care in Africa, highlighting NGO initiatives, past challenges, and future opportunities.

Methods
A narrative review was conducted using PubMed/Medline, ScienceDirect, and other relevant organizational websites.

Results
Over 90% of patients in Africa lack access to proper surgical care due to funding shortages, inadequate resources, and a lack of skilled personnel. NGOs have addressed these gaps through successful initiatives, including fundraising and training, although past failures emphasize the need for clearer objectives and sustainable strategies.

Discussion
Future efforts should prioritize addressing cultural sensitivities, setting realistic goals, and leveraging telemedicine. NGOs and humanitarian organizations will remain critical to improving surgical care for underserved populations in Africa.
Advancements in nanohydroxyapatite: synthesis, biomedical applications and composite developments
Authors: Zhao Rui , Meng Xiang , Pan Zixian , Li Yongjia , Qian Hui , Zhu Xiangdong , Yang Xiao , Zhang Xingdong 
Published: November 2024

Abstract
Nanohydroxyapatite (nHA) is distinguished by its exceptional biocompatibility, bioactivity and biodegradability, qualities attributed to its similarity to the mineral component of human bone. This review discusses the synthesis techniques of nHA, highlighting how these methods shape its physicochemical attributes and, in turn, its utility in biomedical applications. The versatility of nHA is further enhanced by doping with biologically significant ions like magnesium or zinc, which can improve its bioactivity and confer therapeutic properties. Notably, nHA-based composites, incorporating metal, polymeric and bioceramic scaffolds, exhibit enhanced osteoconductivity and osteoinductivity. In orthopedic field, nHA and its composites serve effectively as bone graft substitutes, showing exceptional osteointegration and vascularization capabilities. In dentistry, these materials contribute to enamel remineralization, mitigate tooth sensitivity and are employed in surface modification of dental implants. For cancer therapy, nHA composites offer a promising strategy to inhibit tumor growth while sparing healthy tissues. Furthermore, nHA-based composites are emerging as sophisticated platforms with high surface ratio for the delivery of drugs and bioactive substances, gradually releasing therapeutic agents for progressive treatment benefits. Overall, this review delineates the synthesis, modifications and applications of nHA in various biomedical fields, shed light on the future advancements in biomaterials research.