bluuebunny/crossref_metadata_2025_split huggingface dataset:
Leaving Productivism behind: Towards a Holistic and Processual Philosophy of Ecological Management
Authors: Heikkurinen Pasi , Ruuska Toni , Kuokkanen Anna , Russell Sally 
Published: January 2019

AbstractThis article examines parallels between the increasing mental burnout and environmental overshoot in the organisational context. The article argues that there is a particular philosophy of management that connects these two phenomena of overshoot and burnout, namely productivism. As there are boundaries in all ecological processes and systems, the productivist aim of having ever more output and growth is deemed absurd. It is proposed that productivity as a management philosophy not only leads to mental ill-health in organisations but also to overshoot in the environment. The article concludes that productivism, which denies the limits in utilisation of humans and other natural resources, fits poorly with circular economy and sustainability. Hence, ecological management should be complemented with a more holistic and processual view of organizations, as well as have an aim of peaceful coexistence between all earthbound objects. This signifies acknowledging and caring for human and non-human needs both now and in future by applying the idea of moderation to production of goods and services.
Digital depression screening in HIV primary care in South Africa: mood in retroviral + application monitoring [MIR + IAM]
Authors: Passchier R. V , Owens S. E , Wickremsinhe M. N , Bismilla N. , Ebuenyi I. D 
Published: January 2019

Background.Integrating mental health care into HIV services is critical to addressing the high unmet treatment needs for people living with HIV and comorbid major depressive disorder. Introducing routine mental health screening at the primary health care level is a much needed diagonal approach to enhancing HIV care. In low-resource settings with a shortage of mental health care providers, eMental Health may provide a novel opportunity to attenuate this treatment gap and strengthen the health system.Objective.To conduct formative health systems research on the implementation of routine depression screening using a digital tool – Mood in Retroviral Positive Individuals Application Monitoring (MIR + IAM) – in an HIV primary care setting in South Africa.Methods.A Theory of Change (ToC) approach was utilised through individual and group session interviews to design an intervention that is embedded in the local context. Ten experts and local stakeholders were selected from the UK and South Africa. Data were analysed thematically using Atlas.ti to identify interventions, assumptions, barriers and facilitators of implementation.Findings.The participants considered digital depression screening in HIV care services relevant for the improvement of mental health in this population. The six main themes identified from the ToC process were: (1) user experience including acceptability by patients, issues of patient privacy and digital literacy, and the need for a patient-centred tool; (2) benefits of the digital tool for data collection and health promotion; (3) availability of treatment after diagnosis; (4) human and physical resource capacity of primary health care; (5) training for lay health care workers; and (6) demonstration of the intervention's usefulness to generate interest from decision-makers.Conclusion.Digital depression screening coupled with routine mental health data collection and analysis in HIV care is an applicable service that could improve the mental and physical health outcomes of this population. Careful consideration of the local health system capacity, including both workers and patients, is required. Future research to refine this intervention should focus on service users, government stakeholders and funders.
Stabilisation and drag reduction of pipe flows by flattening the base profile
Authors: Marensi Elena , Willis Ashley P. , Kerswell Rich R. 
Published: January 2019

Recent experimental observations (Kühnen et al., Nat. Phys., vol. 14, 2018b, pp. 386–390) have shown that flattening a turbulent streamwise velocity profile in pipe flow destabilises the turbulence so that the flow relaminarises. We show that a similar phenomenon exists for laminar pipe flow profiles in the sense that the nonlinear stability of the laminar state is enhanced as the profile becomes more flattened. The flattening of the laminar base profile is produced by an artificial localised body force designed to mimic an obstacle used in the experiments of Kühnen et al. (Flow Turbul. Combust., vol. 100, 2018a, pp. 919–943) and the nonlinear stability measured by the size of the energy of the initial perturbations needed to trigger transition. Significant drag reduction is also observed for the turbulent flow when triggered by sufficiently large disturbances. In order to make the nonlinear stability computations more efficient, we examine how indicative the minimal seed – the disturbance of smallest energy for transition – is in measuring transition thresholds. We first show that the minimal seed is relatively robust to base profile changes and spectral filtering. We then compare the (unforced) transition behaviour of the minimal seed with several forms of randomised initial conditions in the range of Reynolds numbers $Re=2400$–$10\,000$ and find that the energy of the minimal seed after the Orr and oblique phases of its evolution is close to that of a critical localised random disturbance. In this sense, the minimal seed at the end of the oblique phase can be regarded as a good proxy for typical disturbances (here taken to be the localised random ones) and is thus used as initial condition in the simulations with the body force. The enhanced nonlinear stability and drag reduction predicted in the present study are an encouraging first step in modelling the experiments of Kühnen et al. and should motivate future developments to fully exploit the benefits of this promising direction for flow control.
Compressible mixing layer in shock-induced separation
Authors: Dupont P. , Piponniau S. , Dussauge J. P. 
Published: January 2019

Unsteadiness in separated shock–boundary layer interactions have been previously analysed in order to propose a scenario of entrainment–discharge as the origin of unsteadiness. It was assumed that the fluid in the separated zone is entrained by the free shear layer formed at its edge, and that this layer follows the properties of the canonical mixing layer. This last point is addressed by reanalysing the velocity measurements in an oblique shock reflection at a nominal Mach number of 2.3 and for two cases of flow deviation ($8^{\circ }$ and $9.5^{\circ }$). The rate of spatial growth of this layer is evaluated from the spatial growth of the turbulent stress profiles. Moreover, the entrainment velocity at the edge of the layer is determined from the mean velocity profiles. It is shown that the values of turbulent shear stress, spreading rate and entrainment velocity are consistent, and that they follow the classical laws for turbulent transport in compressible shear layers. Moreover, the measurements suggest that the vertical normal stress is sensitive to compressibility, so that the anisotropy of turbulence is affected by high Mach numbers. Dimensional considerations proposed by Brown & Roshko (J. Fluid Mech., vol. 64, 1974, 775–781) are reformulated to explain this observed trend.
Georgia, the European Union, and the Visa-Free Travel Regime: Between European Identity and Strategic Pragmatism
Authors: Loda Chiara 
Published: January 2019

AbstractIn March 2017, Georgian citizens were able to travel visa-free to the Schengen Area. This development was highly significant to Georgia, whose narrative of “belonging to Europe” has long contrasted with the travel restrictions for Georgian citizens, who were previously required to undergo complicated consular procedures. However, this was far from being a routine bilateral negotiation. Visa disparities mirrored the contractual asymmetry between Tbilisi and Brussels. This article focuses on how Georgia calibrated its political discourse vis-à-vis the European Union. After outlining both the symbolic and political relevance of visa liberalization, this work assesses the Georgian political rhetoric at different times: in 2005, when Georgia unilaterally lifted visa requirements for Western visitors, and in 2015 and 2016, when visa liberalization was widely expected. The article’s theoretical framework and the final conclusions are relevant to the study of visa regimes and the external relations of small states.
Interplanetary Scintillation with the Murchison Widefield Array V: An all-sky survey of compact sources using a modern low-frequency radio telescope
Authors: Morgan J. S. , Macquart J.-P. , Chhetri R. , Ekers R. D. , Tingay S. J. , Sadler E. M. 
Published: January 2019

AbstractWe describe the parameters of a low-frequency all-sky survey of compact radio sources using Interplanetary Scintillation, undertaken with the Murchison Widefield Array. While this survey gives important complementary information to low-resolution survey, providing information on the sub-arsecond structure of every source, a survey of this kind has not been attempted in the era of low-frequency imaging arrays such as the Murchison Widefield Array and LOw Frequency Array. Here we set out the capabilities of such a survey, describing the limitations imposed by the heliocentric observing geometry and by the instrument itself. We demonstrate the potential for Interplanetary Scintillation measurements at any point on the celestial sphere and we show that at 160 MHz, reasonable results can be obtained within 30° of the ecliptic (2πstr: half the sky). We also suggest some observational strategies and describe the first such survey, the Murchison Widefield Array Phase I Interplanetary Scintillation survey. Finally we analyse the potential of the recently upgraded Murchison Widefield Array and discuss the potential of the Square Kilometre Array-low to use Interplanetary Scintillation to probe sub-mJy flux density levels at sub-arcsecond angular resolution.
Overview OF14C release from irradiated zircaloys in geological disposal conditions
Authors: Necib S , Bucur C , Caes S , Cochin F , Cvetković B Z , Fulger M , Gras J M , Herm M , Kasprzak L , Legand S , Metz V , Perrin S , Sakuragi T , Suzuki-Muresan T 
Published: January 2019

ABSTRACTCarbon-14 (radiocarbon,14C) is a long-lived radionuclide (5730 yr) of interest regarding the safety for the management of intermediate level wastes (ILW). The present study gives an overview of the release of14C from irradiated Zircaloy cladding in alkaline media.14C is found either in the alloy part of Zircaloy cladding due to the neutron activation of14N impurities by14N(n,p)14C reaction, or in the oxide layer (ZrO2) formed at the metal surface by the neutron activation of17O from UO2or (U-Pu)O2fuel and water from the primary circuit in the reactor by17O(n,α)14C reaction. Various irradiated and unirradiated Zircaloys have been studied. The total14C inventory has been determined both experimentally and by calculations. The results seem to be in good agreement. Leaching experiments were conducted in alkaline media for several time durations.14C was mainly released as carboxylic acids. Further, corrosion measurements were performed by using both hydrogen measurements and electrochemical measurements. The corrosion rate (CR) ranges from a few nm/yr to 100 nm/yr depending on the surface conditions and the method used for measurement. From a safety assessment point of view, the instant release fraction (IRF) was determined on irradiated Zircaloy-2. The results showed that the14C inventory in the oxide was significantly below the 20% commonly used in safety case assessments.
Overview of CAST project
Authors: Norris Simon , Capouet Manuel 
Published: January 2019

ABSTRACTThe European Commission CAST project (CArbon-14 Source Term) aimed to develop understanding of the potential release mechanisms of carbon-14 (radiocarbon, 14C) from radioactive waste materials under conditions relevant to waste packaging and disposal to underground geological disposal facilities. The project focused on the release of carbon-14 as dissolved and gaseous species from irradiated metals (steels, Zircaloys), from spent ion-exchange materials and from irradiated graphites. This paper provides an overview of the CAST project and its output. It also acts as an introduction and scene-setter to the other papers in this special edition of Radiocarbon.
PRIVATE INTERNATIONAL LAW IMPLICATIONS OF ‘EQUAL CIVIL PARTNERSHIPS’
Authors: Ní Shúilleabháin Máire 
Published: January 2019

AbstractThe Steinfeld and Keidan campaign for ‘equal civil partnerships’ is focussed on English domestic law. However, it also has profound implications from a private international law perspective. If the UK parliament extends civil partnership to include different-sex couples, this will close a long-standing gap in English private international law. If, on the other hand, it was decided to abolish civil partnership, this would extend the existing lacuna in English private international law, and might generate further collisions with human rights norms. This article explores these lacunae and associated human rights concerns—and suggests possible solutions.
Effects of palm kernel cake (Elaeis guineensis) on intake, digestibility, performance, ingestive behaviour and carcass traits in Nellore bulls
Authors: Cruz Claudia H. , Silva Thadeu M. , Santana Filho Nivaldo B. , Leão André G. , Ribeiro Ossival L. , Carvalho Gleidson G. P. , Bezerra Leilson R. , Oliveira Ronaldo L. 
Published: January 2019

AbstractThe objective of the current experiment was to determine the effects of increasing levels of palm kernel cake in a finishing diet on feed intake, digestibility, performance, ingestive behaviour and carcass traits in zebu bulls. Thirty-two Nellore bulls (420 ± 25.0 kg initial body weight [BW] and 24-months-old), were assigned randomly to individual pens with four treatments (0, 70, 140 and 210 g/kg of palm kernel cake by total dry matter [DM]) and eight replicates per treatment. The inclusion of palm kernel cake linearly decreased DM, crude protein and non-fibrous carbohydrate intake and increased ether extraction intake and digestibility. There was a linear decrease in final BW and hot carcass weight (HCW) associated with palm kernel cake inclusion in the bull diet. However, the gain : feed ratio was similar among the diets. Eating and rumination rates (g DM or neutral detergent fibre/h) were reduced, whereas the total chewing time and idling (min/day) were not affected by palm kernel cake inclusion. There were no effects of palm kernel cake inclusion on most quantitative carcass characteristics and qualitative carcass attributes (subcutaneous fat thickness, longissimus muscle area, colour, texture and marbling). The inclusion of palm kernel cake (up to 210 g/kg total DM) in beef cattle finishing diets decreased eating and rumination rates, thereby decreasing average daily gain and, consequently, final BW and HCW. However, qualitative carcass attributes were not affected by the use of palm kernel cake.
Associations of antenatal glucocorticoid exposure with mental health in children
Authors: Wolford Elina , Lahti-Pulkkinen Marius , Girchenko Polina , Lipsanen Jari , Tuovinen Soile , Lahti Jari , Heinonen Kati , Hämäläinen Esa , Kajantie Eero , Pesonen Anu-Katriina , Villa Pia M. , Laivuori Hannele , Reynolds Rebecca M. , Räikkönen Katri 
Published: January 2019

AbstractBackgroundSynthetic glucocorticoids, to enhance fetal maturation, are a standard treatment when preterm birth before 34 gestational weeks is imminent. While morbidity- and mortality-related benefits may outweigh potential neurodevelopmental harms in children born preterm (<37 gestational weeks), this may not hold true when pregnancy continues to term (⩾37 gestational weeks). We studied the association of antenatal betamethasone exposure on child mental health in preterm and term children.MethodsWe included 4708 women and their children, born 2006–2010, from the Prediction and Prevention of Pre-eclampsia and Intrauterine Growth Restriction Study with information on both antenatal betamethasone treatment and child mental and behavioral disorders from the Finnish Hospital Discharge Register from the child's birth to 31 December 2016. Additional follow-up data on mother-reported psychiatric problems and developmental milestones were available for 2640 children at 3.5 (s.d. = 0.07) years-of-age.ResultsOf the children, 187 were born preterm (61 betamethasone-exposed) and 4521 at term (56 betamethasone-exposed). The prevalence of any mental and behavioral, psychological development, emotional and behavioral, and comorbid disorders was higher in the betamethasone-exposed, compared to non-exposed children [odds ratio 2.76 (95% confidence interval 1.76–4.32), 3.61 (2.19–5.95), 3.29 (1.86–5.82), and 6.04 (3.25–11.27), respectively]. Levels of psychiatric problems and prevalence of failure to meet the age-appropriate development in personal-social skills were also higher in mother-reports of betamethasone-exposed children. These associations did not vary significantly between preterm and term children.ConclusionsAntenatal betamethasone exposure may be associated with mental health problems in children born preterm and in those who end up being born at term.
Trapped in Precariousness: Migrant Agency Workers in China's State-owned Enterprises
Authors: Feng Xiaojun 
Published: January 2019

AbstractThis article develops an integrated perspective to study whether formalization can significantly reduce precariousness for informal workers. This perspective combines the analysis of employment dualism with that of rural–urban dualism and the analysis of the production sphere with that of the social reproduction sphere. By applying this integrated framework to the case of a state-owned enterprise (SOE) in China, this article finds that formalization does little to reduce precariousness for the migrant agency workers there. Migrant agency workers in China are in a precarious position not only because of their employment status but also because of their incomplete citizenship and the commodification of social reproduction materials. With the compensation gap between formal and agency workers narrowed primarily owing to the deterioration of formal employment, formalization has little effect on increasing the income of agency workers or alleviating the financial pressure upon them in the sphere of social reproduction; neither can formalization raise migrants up to full citizenship or reduce related precariousness.
Balloon atrial septostomy at the bedside versus the catheterisation laboratory
Authors: Gopalakrishnan Arun , Krishnamoorthy Kavassery Mahadevan , Sivasubramonian Sivasankaran 
Published: January 2019

AbstractA shorter umbilical venous approach provides an opportunity for balloon atrial septostomy in the younger neonate as opposed to those who present at the end of first week of life. However, the ideal choice of access for a bedside balloon atrial septostomy is not well established. Wouldn’t prostaglandin infusion be a safer option for transport of babies with dextro-transposition in the neonatal period, when the arterial duct can be kept open? A prenatal diagnosis of dextro-transposition facilitates monitoring and planning of septostomy in the early neonatal period explaining why babies underwent bedside procedures more often.
Properties of Whistler Mode Waves in Earth's Plasmasphere and Plumes
Authors: Shi Run , Li Wen , Ma Qianli , Green Alex , Kletzing Craig A. , Kurth William S. , Hospodarsky George B. , Claudepierre Seth G. , Spence Harlan E. , Reeves Geoff D. 
Published: January 2019

AbstractWhistler mode wave properties inside the plasmasphere and plumes are systematically investigated using 5‐year data from Van Allen Probes. The occurrence and intensity of whistler mode waves in the plasmasphere and plumes exhibit dependences on magnetic local time, L, and AE. Based on the dependence of the wave normal angle and Poynting flux direction on L shell and normalized wave frequency to electron cyclotron frequency (fce), whistler mode waves are categorized into four types. Type I: ~0.5 fce with oblique wave normal angles mostly in plumes; Type II: 0.01–0.5 fce with small wave normal angles in the outer plasmasphere or inside plumes; Type III: <0.01 fce with oblique wave normal angles mostly within the plasmasphere or plumes; Type IV: 0.05–0.5 fce with oblique wave normal angles deep inside the plasmasphere. The Poynting fluxes of Type I and II waves are mostly directed away from the equator, suggesting local amplification, whereas the Poynting fluxes of Type III and IV are directed either away from or toward the equator, and may originate from other source regions. Whistler mode waves in plumes have relatively small wave normal angles with Poynting flux mostly directed away from the equator and are associated with high electron fluxes from ~30 keV to hundreds of keV, all of which support local amplification. Whistler mode wave amplitudes in plumes can be stronger than typical plasmaspheric hiss, particularly during active times. Our results provide critical insights into understanding whistler mode wave generation inside the plasmasphere and plumes.
Nimbolide protects against endotoxin-induced acute respiratory distress syndrome by inhibiting TNF-α mediated NF-κB and HDAC-3 nuclear translocation
Authors: Pooladanda Venkatesh , Thatikonda Sowjanya , Bale Swarna , Pattnaik Bijay , Sigalapalli Dilep Kumar , Bathini Nagendra Babu , Singh Shashi Bala , Godugu Chandraiah 
Published: January 2019

AbstractAcute respiratory distress syndrome (ARDS) is characterized by an excessive acute inflammatory response in lung parenchyma, which ultimately leads to refractory hypoxemia. One of the earliest abnormalities seen in lung injury is the elevated levels of inflammatory cytokines, among them, the soluble tumor necrosis factor (TNF-α) has a key role, which exerts cytotoxicity in epithelial and endothelial cells thus exacerbates edema. The bacterial lipopolysaccharide (LPS) was used both in vitro (RAW 264.7, THP-1, MLE-12, A549, and BEAS-2B) and in vivo (C57BL/6 mice), as it activates a plethora of overlapping inflammatory signaling pathways involved in ARDS. Nimbolide is a chemical constituent of Azadirachta indica, which contains multiple biological properties, while its role in ARDS is elusive. Herein, we have investigated the protective effects of nimbolide in abrogating the complications associated with ARDS. We showed that nimbolide markedly suppressed the nitrosative-oxidative stress, inflammatory cytokines, and chemokines expression by suppressing iNOS, myeloperoxidase, and nitrotyrosine expression. Moreover, nimbolide mitigated the migration of neutrophils and mast cells whilst normalizing the LPS-induced hypothermia. Also, nimbolide modulated the expression of epigenetic regulators with multiple HDAC inhibitory activity by suppressing the nuclear translocation of NF-κB and HDAC-3. We extended our studies using molecular docking studies, which demonstrated a strong interaction between nimbolide and TNF-α. Additionally, we showed that treatment with nimbolide increased GSH, Nrf-2, SOD-1, and HO-1 protein expression; concomitantly abrogated the LPS-triggered TNF-α, p38 MAPK, mTOR, and GSK-3β protein expression. Collectively, these results indicate that TNF-α-regulated NF-κB and HDAC-3 crosstalk was ameliorated by nimbolide with promising anti-nitrosative, antioxidant, and anti-inflammatory properties in LPS-induced ARDS.