bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ruptured popliteal artery aneurysms
Authors: Akman James , Katsogridakis Emmanuel , Antoniou George A 
Published: February 2019

Background Rupture is a recognised complication of ruptured popliteal artery aneurysms that requires emergency intervention. There is little evidence collating the presentation, intervention and outcomes of ruptured popliteal artery aneurysms. Objective The primary aim of this study was to deduce the sequelae following different management modalities of ruptured popliteal artery aneurysm. Methods We performed a systematic review of all available cases reports of ruptured popliteal artery aneurysms in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analysis Protocol. Results We identified 48 cases taken from 35 case reports and series. Men were more commonly affected ( n = 96%), and mean age was 71 years. Acute limb ischemia was the commonest presentation (32%) whilst incidental deep vein thrombosis was found in 43% of patients. The mean aneurysm size was 8.2 cm (range, 2.7 to 13.3 cm). Management consisted of open surgery (58%), endovascular treatment (25%) and ‘other’ treatment (evacuation of haematoma, ligation of aneurysm, amputation or palliation) (17%). The perioperative mortality rate in the whole cohort was 13%. Perioperative mortality was similar between comparing the open and endovascular surgery groups. Re-intervention rate amongst endovascular patients was 25% over an average follow-up period of 14 months. There was one re-intervention in the re-constructive group (3%) over a follow-up period of 17 months and none in the ‘other’ group. Conclusion Popliteal artery aneurysm rupture is a serious complication associated with significant morbidity and mortality. Open surgical reconstruction and endovascular repair are both feasible for the treatment of ruptured popliteal artery aneurysms; however, open surgery is less likely to require further re-intervention.
Mindfulness and its relevance for sports coaches adopting nonlinear pedagogy
Authors: Kee Ying Hwa 
Published: February 2019

Nonlinear pedagogy is an approach for structuring skills acquisition that is underpinned by dynamical systems theory and ecological psychology approach of appreciating motor behavior. Given that nonlinear pedagogy calls for a different set of coaching strategies that departs from the traditional prescriptive approach, a heightened level of mindfulness—underpinned by attention/awareness and acceptance (Bishop et al., Mindfulness: a proposed operational definition. Clinical Psychology: Science and Practice 2004; 11(3): 230–241)—on coaches’ part may be particularly pertinent for facilitating this creativity-based and learner-centered approach. In this paper, the relevance of the mindfulness construct is discussed with reference to the need for coaches implementing nonlinear pedagogy to (a) develop sensitivity towards the dynamics of the movement system, (b) be open about impending variability and creativity in learner’s behavior, and (c) be accepting towards learners for who they are. The case for how coaches with heightened mindfulness might be better apt to accomplish the above is put forth. Some suggestions for future work in this area are also suggested. In line with the complex systems perspective in skills acquisition, perhaps it is not too far-fetched to consider a coach’s level of mindfulness during the coaching session as an important control parameter within a larger movement system that has a role in determining learner’s success in skill acquisition.
CardioMems® device implantation reduces repeat hospitalizations in heart failure patients: A single center experience
Authors: Assaad Mahmoud , Sarsam Sinan , Naqvi Amir , Zughaib Marcel 
Published: February 2019

Introduction Hospital readmission for congestive heart failure remains one of the most important economic burdens on healthcare cost. The implantation of a wireless pressure monitoring device (CardioMEMS®) had led to nearly 40% reduction in readmission rates in the landmark CHAMPION trial. We aim to study the effectiveness of this wireless device in reducing heart failure admissions in a real-world setting. Methods This is a retrospective chart review of patients with recurrent admissions for heart failure implanted with the wireless pressure monitoring system (CardioMEMS®) at our institution. We studied the total number of all-cause hospital admissions as well as heart failure-related admissions pre- and post-implantation. Results A total of 27 patients were followed for 6–18 months. The total number of all-cause hospital admissions prior to device implantation was 61 admissions for all study patients, while the total number for the post-implantation period was 19, correlating with 2.26 + 1.06 admissions/person-year prior to device implantation versus 0.70 + 0.95 admissions/person-year post-implantation (p-value < 0.001). For heart failure-related admissions, the total number prior to device implantation was 46 compared to 9 admissions post device implantations, correlating with 1.70 + 1.07 admissions/person-years pre-implantation versus 0.33 + 0.62 admissions/person-years post-implantation (p-value < 0.001). This translates to 80.4% and 68.9% reduction in heart failure and all-cause admissions, respectively. Conclusion In a real-world setting, the implantation of a wireless heart failure monitoring system in patients with heart failure and class III symptoms has resulted in 80.4% reduction in heart failure admissions and 69% reduction in all-cause admissions.
Diagnostic accuracy of faecal calprotectin in patients with active perianal fistulas
Authors: Stevens Toer W , D'Haens Geert R , Duijvestein Marjolijn , Bemelman Willem A , Buskens Christianne J , Gecse Krisztina B 
Published: February 2019

BackgroundFaecal calprotectin (FC) is a marker of mucosal inflammation.ObjectiveThe aim of this study was to determine the diagnostic accuracy of FC to (a) differentiate between perianal fistulizing Crohn's disease (pCD) and cryptoglandular perianal fistulas; and (b) detect mucosal inflammation in pCD.MethodsPatients with active perianal fistulas who had FC measured and a complete ileocolonoscopy within 10 weeks were retrospectively included.ResultsFifty‐six patients were included (pCD, n = 37) of whom 19 pCD patients exhibited ulcers. FC was significantly higher in pCD compared to cryptoglandular fistulas (µg/g) (708.0 (207.0–1705.0) vs 32.0 (23.0–77.0), p < 0.001). Area‐under‐the‐curve (AUC) value for FC receiver operating characteristic (ROC) statistics was 0.900. Optimal FC cut‐off was ≥ 150 µg/g. To differentiate pCD from cryptoglandular fistulas in the absence of luminal inflammation, optimal cut‐off remained ≥ 150 µg/g (AUC = 0.857, sensitivity = 0.81, specificity = 0.89, positive predictive value (PPV) = 93.8% and negative predictive value (NPV) = 70.8%). In pCD, FC was significantly increased in the presence of ulcers (1672.0 vs 238.0, p = 0.004). Optimal cut‐off was ≥ 250 µg/g (AUC = 0.776; sensitivity = 0.89, specificity = 0.56, PPV ‐ 68.0% and NPV = 83.0%).ConclusionFC discriminates pCD from cryptoglandular fistulas, even in the absence of intestinal ulcers. In active pCD, an elevated FC does not accurately predict the presence of ulcers and should be interpreted with caution.
Hyperpolarised129Xe magnetic resonance imaging to monitor treatment response in children with cystic fibrosis
Authors: Rayment Jonathan H. , Couch Marcus J. , McDonald Nancy , Kanhere Nikhil , Manson David , Santyr Giles , Ratjen Felix 
Published: February 2019

Pulmonary magnetic resonance imaging using hyperpolarised129Xe gas (XeMRI) can quantify ventilation inhomogeneity by measuring the percentage of unventilated lung volume (ventilation defect per cent (VDP)). While previous studies have demonstrated its sensitivity for detecting early cystic fibrosis (CF) lung disease, the utility of XeMRI to monitor response to therapy in CF is unknown. The aim of this study was to assess the ability of XeMRI to capture treatment response in paediatric CF patients undergoing inpatient antibiotic treatment for a pulmonary exacerbation.15 CF patients aged 8–18 years underwent XeMRI, spirometry, plethysmography and multiple-breath nitrogen washout at the beginning and end of inpatient treatment of a pulmonary exacerbation. VDP was calculated from XeMRI images obtained during a static breath hold using semi-automated k-means clustering and linear binning approaches.XeMRI was well tolerated. VDP, lung clearance index and the forced expiratory volume in 1 s all improved with treatment; however, response was not uniform in individual patients. Of all outcome measures, VDP showed the largest relative improvement (−42.1%, 95% CI −52.1–−31.9%, p<0.0001).These data support further investigation of XeMRI as a tool to capture treatment response in CF lung disease.
Effıcacy and safety of dapagliflozin on diabetic patients receiving high-doses of insulin
Authors: Sertbas Meltem , Sertbas Yasar , Okuroglu Nalan , Akyildiz Ali Burkan , Sancak Seda , Ozdemir Ali 
Published: February 2019

Objective: In this study we aimed to investigate the efficacy and safety of dapagliflozin addition to diabetic patients using high dose insulin.
Methods: The current study was carried out in the outpatient diabetic clinics of Fatih Sultan Mehmet Education and Research Hospital. Thirty diabetic patients who were receiving high dose (>0.5U/kg) insulin and oral antidiabetic treatment (other than SGLT 2 inhibitors) were included in this study. Primary end point was the change in HbA1c, insulin doses and serum electrolyte from the addition of dapagliflozin 10 mg to the week 12.
Results: At the end of three month BMI were obviously decreased from 33.31±4.51 to 32.14±4.66 (p: 0.001). There was also an evident decrease of insulin requirement from 76±23.15 U/kg to 57.60±17.61 U/day (p<0.001). As well as the decrease in insulin doses, there was also a significant decline in HbA1c (Δ 1.6 %) and fasting blood glucose levels (Δ68.6 mg/dl) (p<0.001). Among serum electrolyte levels slight but meaningful increase of blood urea nitrogen (BUN) and sodium (Na) levels were seen (p: 0.044 and p: 0.026). There were no significant changes in serum cholesterol levels with electrolytes such as potassium, calcium, phosphorus magnesium and vitamin D (p>0.05).
Conclusion: In diabetic patients with inadequately controlled glucose regulation despite high-dose insulin therapy, dapagliflozin may be an alternative combination choice to decrease the need of insulin dose and obtain an optimal HbA1c, fasting plasma glucose levels and weight without major side effects.
How to cite this:Sertbas M, Sertbas Y, Okuroglu N, Akyildiz AB, Sancak S, Ozdemir A. Effıcacy and safety of dapagliflozin on diabetic patients receiving high-doses of insulin. Pak J Med Sci. 2019;35(2):399-403. doi: https://doi.org/10.12669/pjms.35.2.21
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
A novel ultrasound technique to detect early chronic kidney disease
Authors: Hewadikaram Dulitha K. , Bandara Mudhitha , Pattivedana Amal N. , Jayaweera Hiran H. E. , Jayananda Kithsiri M. , Madhavi W. A. Monica , Pallewatte Aruna , Jayasumana Channa , Siribaddana Sisira , Wansapura Janaka P. 
Published: February 2019

Chronic kidney disease (CKD) of unknown etiology is recognized as a major public health challenge and a leading cause of morbidity and mortality in the dry zone in Sri Lanka. CKD is asymptomatic and are diagnosed only in late stages. Evidence points to strong correlation between progression of CKD and kidney fibrosis. Several biochemical markers of renal fibrosis have been associated with progression of CKD. However, no marker is able to predict CKD consistently and accurately before being detected with traditional clinical tests (serum creatinine, and cystatin C, urine albumin or protein, and ultrasound scanning). In this paper, we hypothesize that fibrosis in the kidney, and therefore the severity of the disease, is reflected in the frequency spectrum of the scattered ultrasound from the kidney. We present a design of a simple ultrasound system, and a set of clinical and laboratory studies to identify spectral characteristics of the scattered ultrasound wave from the kidney that correlates with CKD. We believe that spectral parameters identified in these studies can be used to detect and stratify CKD at an earlier stage than what is possible with current markers of CKD.
Potential predictors of adoption of the Tobacco Heating System by U.S. adult smokers: An actual use study
Authors: Roulet Steve , Chrea Christelle , Kanitscheider Claudia , Kallischnigg Gerd , Magnani Pierpaolo , Weitkunat Rolf 
Published: February 2019

Background: This was a pre-market actual use study with the Tobacco Heating System (THS), a candidate modified risk tobacco product, conducted with adult smokers in eight cities in the United States. The main goal of the study was to describe THS adoption in a real-world setting. The aim of this analysis was to identify potential predictors for adoption of THS using stepwise logistic regression method. Methods: This actual use study was an observational study assessing self-reported stick-by-stick consumption of the THS product compared with the use of commercial cigarettes over six weeks. The study aimed at replicating the usage of THS in real-world conditions with participants being able to consume cigarettes, THS, and any other nicotine-containing products (e.g., e-cigarettes, cigars, etc.) ad libitum. Results: 14.6% of participants adopted THS, which comprised 70% or more of their total tobacco consumption by the end of the observational period (in Week 6). The main predictors of adoption were the liking of the smell, taste, aftertaste, and ease of use of THS. The proportion of adoption was higher in participants aged 44 years and older and in Hispanic or Latino adult smokers. Additionally, adoption of THS was more likely in participants who had never attempted to quit smoking and in participants who smoked up to 10 cigarettes per day. Finally, the adoption of THS was higher in participants who consumed both regular and menthol THS compared with those who consumed only one THS variant. Conclusions: The main predictors of THS adoption were positive sensory assessment and the ease of use. Socio-demographic characteristics and smoking habits appeared much less important. Post-marketing studies will provide further insights on the impact of the THS at the individual and the overall population level.
Raising concerns – you and your colleagues
Authors: Bridges Glenys 
Published: February 2019

Glenys Bridges considers the who, what, why, where and when Aim This article aims to enable dental nurses to: Recognise when a colleague's health, behaviour or professional performance is placing patients at risk, know when and how to raise concerns, and identify sources of guidance and support. Objectives On completion of this article, the reader will be able to: Act in line with fitness to practise guidance to maintain professional standards Follow practice policies and procedures for raising concerns Know when concerns should involve outside regulators.
Paroxysmal Supraventricular Tachycardia in Children : The Role of Infectious Diseases and Its Relationship to Serum Enzyme
Authors: Wahab A. Samik 
Published: February 2019

The records of 28 children whose first episode of paroxysmal supraventricular tachycardia occurred before 12 years (median age 10 months) were reviewed. There were 17 males and 11 females. In 17 cases the first attack occurred before the first year and in 11 of these it occurred after the first year. One case had congenital heart disease (ASD). The WPW syndrome was diagnosed in 3 cases. When first seen, most of the infants presented with signs of incipient or manifest congestive heart failure. In almost ninetenth fo cases rhere was an increased of serum enzymes (lactic dehydrogenase, creatinephosphokinase and glutamic oxaloaccetic transaminase. Digitals was effective against congestive heart failure and when continued, might prevent failure during subsequent attacks. Antiarrhythmic agents other than digitals were not used. It is recommended to continue digitalis treatment for at least one year in all patients with SVT, whether or not the first episode terminated spontaneously.
Ventricular tachycardia in children with diphtheritic myocarditis
Authors: Wahab A. Samik 
Published: February 2019

Nine children with diphtheritic ventricular tachycardia ranging in age from 2 to 11 years (mean 6.5 years) were observed and followed up until their terminal state. The ventricular tachycardia showed a left bundle branch block contour in 5 of 9 patients, right bundle branch block in four, multifocal pacemaker in three and unifocal in six patients. Fusion and captured beats were present in two and 4 patients respectively, Including one patient who had both. Four cases were without obvious atrio-ventricular dissociation.
All patients were treated with standard therapy for diphtheria, and prednison was given to patients with myocarditis. Because of its controversial results, antwrrhythm1c agent was not given.
The prognosis is very poor; all patients died one to 8 days after ventricular tachycardia appearance.
Peran Himpunan Mahasiswa dalam Pengembangan Koleksi di Perpustakaan Politeknik Negeri Semarang
Authors: Suwanto Sri Ati 
Published: February 2019

Penelitian ini membahas mengenai Peran Himpunan Mahasiswa Divisi Perpustakaan dalam Pengembangan Koleksi di Perpustakaan Elektro Politeknik Negeri Semarang”. Tujuan Penelitian ini untuk mengetahui peran himpunan mahasiswa khususnya divisi perpustakaan dalam kegiatan pengembangan koleksi di Perpustakaan Elektro Politeknik Negeri Semarang. Metode penelitian yang digunakan pada penelitian ini adalah penelitian kualitatif dengan pendekatan deskriptif, jenis studi kasus. Pemilihan informan dalam penelitian ini menggunaka teknik pusposive sampling, yaitu dengan pertimbangan mahasiswa yang terlibat dan melakukan kegiatan pengembangan koleksi di Perpustakaan Elektro Politeknik Negeri Semarang serta mengetahui kegiatan Himpunan Mahasiswa. Teknik Pengumpulan data dilakukan dengan observasi, wawancara dan dokumen. Berdasarkan analisis data diketahui bahwa himpunan mahasiswa divisi perpustakaan sangat berperan dalam proses pengembangan koleksi di Perpustakaan Elektro Politeknik Negeri Semarang. Kegiatan yang dilakukan oleh divisi perpustakaan himpunan mahasiswa adalah menganalisis kebutuhan pengguna, melakukan kebijakan pengembangan koleksi, seleksi bahan pustaka, dan melakukan pengadaan. Kegiatan pengembangan koleksi dilakukan sebagai program kerja divisi perpustakaan himpunan mahasiswa.
Pengaruh Perilaku Asertif Pustakawan dalam Keberhasilan Program Liaison Librarian di Perpustakaan
Authors: Husna Jazimatul 
Published: February 2019

Perpustakaan sebagai lokomotif ilmu pengetahuan, harus cermat menyikapi dan merespon perubahan tersebut dengan meyiapkan agenda-agenda yang relevan dengan kondisi kekinian dan trend perkembangan keilmuan kepustakawanan yang akan datang. Pustakawan yang dimaksud adalah pustakawan yang mempunyai perilaku asertif. Pustakawan yang mempunyai perilaku asertif sangat berguna dalam berinteraksi dengan pengguna perpustakaan dalam mencarí informasi. Pemustaka yang tentunya memiliki kebutuhan informasi yang berbeda beda. Karena orientasi perpustakaan merupakan kepuasan pengguna (user oriented). Program liaison librarian suatu program yang sangat menarik, dimana pustakawan harus secara aktif dapat memaksimalkan dalam menjalin komunikasi dengan semua pengguna di perpustakaan, dapat melakukan diskusi dan harus menyediakan waktubisa memberikan konsultasi mengenai segala kebutuhan pemustaka terhadap kebutuhan informasi dan sumber-sumber informasi lainya.
SANMAI NO OFUDA DALAM PERSPEKTIF GREIMAS
Authors: Rahmah Yuliani 
Published: February 2019

This paper entitled Sanmai no Ofuda in Greimas’s perspective. Sanmai no ofuda is the title of Japan’s folktale has similarities with localfolktales from several regions in Indonesia. In this paper, the writer tried to explain the narrative structure of Sanmai no Ofuda in Greimas’s perspective.Its mean to reveal the narrative structure of this folktale,the writer used structural naratology approaches with Algirdas Julien Greimas’s theory. The writer tried to understand about the intrinsic elements in Sanmai no Ofuda by examining the actans schemes and functional structure. The findings show that the narrative structure can explain the intrinsic elements more specificly.
NOMINA BERPEMARKAH PARTIKEL O DALAM BAHASA JEPANG
Authors: Rosliana Lina 
Published: February 2019

(Title: Noun Marked by Case Particle O in Japanese). Noun in Japanese is a part of speech that can stand alone, not conjugated, and can occupy the function of the subject, object, as well as predicate in the sentence. Nomina can be named of goods, place name, person's name, profession, number, and others. This diversity makes the nouns in Japanese have different markers, one of which is the case particle o. Basically, case particle o in Japanese have a function as a marker of objects. However, the object function occupied by nouns is not just a target. Noun in Japanese can also be a word related to place or time. This study aims to examine the types of nouns marked by case particle o in Japanese. This research uses the method of distribution studies with agih techniques where the object is the language element studied. This study consists of three stages, namely data collection, data analysis, and data presentation. The data collected in the form of phrases with the construction of N + Po + V from various data sources online and print. The next step is to analyze the data collected by using the basic grouping of nouns from Moriyama (2008). The data that have been analyzed will be presented in descriptive form.Keywords : Noun, Case Particle o, Japanese
PERGESERAN MAKNA DALAM CERPEN HACHI NO JI YAMA
Authors: Rahmah Yuliani 
Published: February 2019

(Title: Meaning Shift in Japanese Short Story “Hachi No Ji Yama”) A literary work will be translated properly according to the original text if an interpreter does the translation procedure appropriately. The translation procedure itself is divided into 14 types, but in the translation process from Japanese into Indonesian, there are three types which commonly used in procedures of the translation process. It is Transposition, Modulation, and Adaptation. This paper tried to explain the use of that three types of translation procedures in a Japanese short story. The short story used as the object of this paper was a children's short story entitled Hachi no Ji Yama by Tsuchida Kohei. Referring to the translation rules, the results are that the Hachi no Ji Yama short story uses 2 translation procedures, which is transposition and modulation. With the differences in the rules of language and grammatical structure between Indonesian and Japanese, the most widely used of transposition procedures are the first and second types, while the modulation used is free modulation.
Synthesis of Polymer Inclusion Membranes based on Cellulose Triacetate for Recovery of Lanthanum(III) from Aqueous Solutions
Authors: Makowka Adam , Pospiech Beata 
Published: February 2019

Abstract
Polymer inclusion membrane (PIM) containing cellulose triacetate (CTA) as a polymer matrix and 2-nitrophenyl octyl ether (NPOE) as a plasticizer was developed. This membrane also contained di(2-ethylhexyl)phosphoric acid (D2EHPA) and tributyl phosphate (TBP) as the carriers of metal ions. The facilitated transport of lanthanum(III) from aqueous nitrate(V) solutions across PIM was studied. It was observed that metal ions were transported from the source phase into 2M H2SO4 as the receiving phase. The transport through PIM with D2EHPA as the ion carrier was found as the more effective method of lanthanum(III) removal from the aqueous solution than transport through PIM with TBP as the ion carrier.