bluuebunny/crossref_metadata_2025_split huggingface dataset:
HUBUNGAN AKTIVITAS FISIK TERHADAP KEJADIAN OBESITAS BERDASARKAN INDEKS MASSA TUBUH DI DESA BANJAROYO
Authors: Christianto Deni Aditya 
Published: February 2019

Obesitas merupakan keadaan kelebihan berat badan yang dapat membawa manifestasi negatif bagi kesehatan. Indeks massa tubuh merupakan parameter dalam menentukan seseorang mengalami obesitas atau tidak, parameter ini sering digunakan karena mudah diterapkan, cepat dan memiliki hasil yang tepat. Salah satu faktor yang berperan penting dalam kejadian obesitas adalah aktivitas fisik, yakni segala pergerakan tubuh yang mengeluarkan energi serta membakar lemak. Tujuan dari penelitian ini adalah mengidentifikasi perbedaan antara aktivitas fisik ringan, sedang dan berat terhadap kejadian obesitas berdasarkan indeks massa tubuh.
Penelitian ini merupakan penelitian observasional analitik dengan jenis penelitian potong lintang. Pengambilan sampel dilakukan secara non-random sampling dengan teknik purposive sampling dan didapat responden sebanyak 236 orang. Pengambilan data aktivitas fisik dilakukan menggunakan kuisioner IPAQ dan perhitungan indeks massa tubuh dengan mengukur berat badan dan tinggi badan. Analisis data penelitian ini menggunakan SPSS 22 dengan taraf kepercayaan 95%. Hasil penelitian menunjukkan tidak terdapat pengaruh yang bermakna (p = 0,18) antara aktivitas fisik berat dan sedang terhadap kejadian obesitas berdasarkan indeks massa tubuh pada warga dewasa di Desa Banjaroyo, Kecamatan Kalibawang, Kabupaten Kulonprogo, Yogyakarta.
Kontekstualisasi Pendidikan Kritis Berbasis Pemikiran Ali Syari’ati di Indonesia
Authors: Susanto Nanang Hasan , Suyuti Imam - 
Published: February 2019

This paper aims to find out the contextualization of the critical ideology of Ali Syari'ati in the field of Islamic education. This paper uses a qualitative approach by gathering various literature on Ali Syari'ati's critical thinking, then analyzing it in the context of national education in Indonesia. The results of the study show that: first, education must be able to free humans from all forms of colonialism. second: the aim of critical education is to create an independent person and become a social prophet (rushan fekr) whose duty is to bring the people towards the desired ideals together, namely social welfare, free from acts of tyranny and misery of the people. third: making enlightened students that they are able to get out of four social prisons which include nature, history, society and human ego. In the context of Islamic education in Indonesia it can be realized by shaping students to be highly critical, independent and socially conscious individuals.Keywords: critical education; Ali Shari'ati; independent; social awareness; human ego; Islamic education; Indonesia; AbstrakTulisan ini bertujuan untuk mengetahui kontekstualisasi ideologi kritis Ali Syari’ati dibidang pendidikan Islam. Tulisan ini menggunakan pendekatan kualitatif dengan mengumpulkan berbagai literatur mengenai pemikiran kritis Ali Syari’ati, kemudian dianalisis dalam konteks pendidikan Nasional di Indonesia. Hasil penelitian menunjukkan bahwa: pertama, Pendidikan harus dapat membebaskan manusia dari semua bentuk penjajahan. kedua: tujuan pendidikan kritis adalah untuk mewujudkan pribadi yang merdeka dan menjadi nabi sosial (rushan fekr) yang bertugas untuk membawa umat menuju cita-cita yang diinginkan bersama, yaitu kesejahteraan sosial, terbebas dari tindak kezaliman dan kesengsaraan umat. ketiga: menjadikan siswa yang tercerahkan yaitu mereka mampu keluar dari empat penjara sosial yang meliputi sifat dasar, sejarah, masyarakat, dan ego manusia. Dalam konteks pendidikan Islam di Indoenesia bisa diwujudkan dengan membentuk anak didik menjadi pribadi yang kritis, independen dan berkesadaran sosial yang tinggi.Kata Kunci: pendidikan kritis; Ali Syari’ati; independen; kesadaran social; ego manusia; pendidikan Islam; Indonesia
Strategi Kepala Lembaga Pengembangan Studi Islam (LPSI) Universitas Ahmad Dahlan Yogyakarta dalam Menginternalisasikan Nilai-nilai Religius Mahasiswa
Authors: Setyaningsih Rini 
Published: February 2019

This study aims to determine the strategy of the Head of the Institute for Development of Islamic Studies (LPSI) of Ahmad Dahlan University Yogyakarta in internalizing religious values to students. The research method uses deskptive qualitative. The Chief Strategy of LPSI to internalize the religious values of students through the 3 stages, first, externalizing values where the LPSI collaborated with the Campus Introduction Program (PPK) committee in providing important information related to the campus Islamization program. second, certification Quranic activity supervisors and student organizations in providing Islamic knowledge. third, value internalization. in the academic realm and in the non-academic realmKeywords: strategy; internalization; religious.AbstrakPenelitian ini bertujuan untuk mengetahui strategi Kepala Lembaga Pengembangan Studi Islam (LPSI) Universitas Ahmad Dahlan Yogyakarta dalam menginternalisasikan nilai-nilai religius kepada mahasiswa. Metode penelitian mengunakan kualitatif deskptif. Strategi Kepala LPSI untuk menginternalisasikan nilai-nilai religius mahasiswa melalui 3 tahapan pertama, eksternalisasi nilai dimana pihak LPSI bekerjasama dengan panitia Program Pengenalan Kampus (PPK) dalam memberikan informasi penting terkait program Islamisasi kampus., kedua, objektivitas, pihak LPSI bekerjasama dengan seluruh dosen AIK dan sertifikasi, pembimbing kegiatan tahsinul-Qur’an dan organisasi mahasiswa dalam memberikan ilmu pengetahuan agama Islam. ketiga, internalisasi nilai dalam ranah akademik dan dalam ranah non-akademik.Kata kunci: strategi; internalisasi; religius;
Dekonstruksi Paradigma Radikal dalam Al-Quran
Authors: Nabilata Lub Liyna 
Published: February 2019

This paper aims to change the radical paradigm based on the verses of the Quran. Religion or verses of Quran often becomes a tool of legitimacy or justification of acts of violence. This research uses the methods of library research. From this research it is achieved that religious radicalism caused by the first war verses, often made up of legitimacy of violence and terrorism in Islam, the second, understanding the Jihad verses translated the war against the enemies of Islam, so that acts of violence against everything that was considered an enemy of Islam is the glorious JihadKeywords: radicalism, religion, violent ideological verses Abstrak Tulisan ini bertujuan untuk merubah paradigma radikal berdasarkan ayat-ayat Al-Quran. Agama atau ayat-ayat al-Qur’an sering menjadi alat legitimasi atau pembenaran atas tindakan kekerasan. Penelitian ini menggunakan metode library research. Dari penelitian ini didapatkan bahwa muculnya radikalisme agama disebabkan oleh pertama, ayat-ayat perang sering dijadikan legitimasi atas pro-kekerasan dan aksi terorisme dalam Islam., kedua, memahami ayat-ayat Jihad diartikan perang melawan musuh Islam, sehingga tindakan kekerasan terhadap segala sesuatu yang dianggap musuh Islam merupakan Jihad yang mulia Kata kunci: Radikalisme, Agama, Ayat-ayat Ideologi kekerasan
Pandangan Keagamaan Pelaku Bom Bunuh Diri di Indonesia
Authors: Nurani Herlina , Nurdin Ahmad Ali 
Published: February 2019

This journal discusses most of the religious discussions launched in Indonesia. This research is library research. Is the result of being found first, understanding the religious texts textually. Second, there are differences of opinion that influence the text that improves development that accommodates modernization theories, thereby increasing disappointment with the government. Third, the existence of understanding as jihad is a holy war against unbelievers because it considers the government system in Indonesia to be changed based on the justice of their religious understanding.Keyword: globalization; religion; radicalism; jihad; AbstrakJurnal ini menelusuri tentang sebagian pandangan keagamaan pelaku bom bunuh diri di Indonesia. Penelitian ini adalah library riset. Adapun hasil yang ditemukan pertama, pemahaman nash-nash agama secara tekstual. Kedua, adanya sikap protes yang mempengaruhi pemahaman teks serta kegagalan pembangunan yang mengakomodasi teori-teori modernisasi, sehingga terjadinya kekecewaan terhadap pemerintah. Ketiga, adanya paham bahwa jihad adalah perang suci sebagai perang untuk melawan orang kafir karena menganggap sistem kepemerintahan di Indonesia harus dirubah berdasarkan kebenaran pemahaman keagamaan mereka. Kata Kunci : globalisasi; agama; radikalisme; jihad;
Protecting sources of urban water supply in Haiti: An institutional analysis
Authors: Martinez Antonio Andres 
Published: February 2019

AbstractWater source protection is essential to ensure the provision of safe drinking water. In Haiti, and elsewhere, this is a dynamic requirement affected by population growth, not least in urban areas. In this paper, the principles of legitimacy, integration, inclusiveness, and capacity have been used to gauge and understand the institutional environment regarding water source protection for urban drinking water provision. The research was based on a review of official documents and key informant interviews. The absence of robust legislation can result in a misinterpretation of institutional responsibilities with respect to both water and land management. The legitimacy of some key institutions is questioned due to unclear legal status, particularly when they are directly appointed by central government. Some institutions have gained recognised authority as a result of their sectoral prominence but lack legal backing. Particular initiatives may foster the integration of stakeholders but, without involving all necessary sectors, agencies and levels of government, their sustainability is questionable. Technical, structural and financial institutional capacities appear limited, hampering the implementation of initiatives and their continuity, also compounded by institutional dependence on external funds and high turnover of administrators.
An Integrative “Omics” Approach, for Identification of Bona Fides PLK1 Associated Biomarker in Esophageal Adenocarcinoma
Authors: Bibi Nousheen , Rashid Sajid , Nicholson Judith , Malloy Mark , O'Neill Rob , Blake David , Hupp Ted 
Published: February 2019

Background:The rapid expansion of genome-wide profiling techniques offers the opportunity to utilize various types of information collected in the study of human health and disease. Overexpression of Polo like kinase 1 (PLK1) is associated with esophageal adenocarcinoma (OAC), however biological functions and molecular targets of PLK1 in OAC are still unknown.Objective:Here we performed integrative analysis of two “omics” data sources to reveal high-level interactions of PLK1 associated with OAC.Methods:Initially, quantitative gene expression (RPKM) was measured from transcriptomics data set of four OAC patients. In parallel, alteration in phosphorylation levels was evaluated in the proteomics data set (mass spectrometry) in OAC cell line (PLK1 inhibited). Next, two “omics” data sets were integrated and through comprehensive analysis possible true PLK1 targets that may serve as OAC biomarkers were assembled.Results:Through experimental validation, small ubiquitin-related modifier 1 (SUMO1) and heat shock protein beta-1 (HSPB1) were identified as novel phosphorylation targets of PLK1. Consequently in vivo, in situ and in silico experiments clearly demonstrated the interaction of PLK1 with putative novel targets (SUMO1 and HSPB1).Conclusion:Identification of a PLK1 dependent biosignature in OAC with high confidence in two omics levels proven the robustness and efficacy of our integrative approach.
Interventional Bronchoscopy in the Management of Chronic Obstructive Lung Disease
Authors: Bilaçeroğlu Semra 
Published: February 2019

Background:
Chronic obstructive pulmonary disease (COPD) is characterized by airflow
limitation, hyperinflation and reduced gas exchange that lead to progressive dyspnea. Pulmonary
rehabilitation, lifestyle changes, pharmacotherapy, long-term oxygen therapy, noninvasive
ventilation and surgical therapeutic approaches are the basic management strategies.

Purpose:
In the last 15 years, various bronchoscopic therapeutic modalities have emerged for severe
COPD. The aim of this review is to summarize the effects of these bronchoscopic treatments
compared with lung rehabilitation and pharmacological therapies.

Methods:
A PubMed search for the eligible studies and reviews on interventional bronchoscopy and
COPD has been conducted.

Results:
Bronchoscopic lung volume reduction (LVR) techniques are targeted to reduce
hyperinflation. The efficacy of reversible valve implantation has been confirmed in several
randomized controlled trials. It provides clinical benefit in the absence of interlobar collateral
ventilation. Nonblocking bronchoscopic LVR with coils, thermal vapor or sealants is independent of
collateral ventilation but has not been studied sufficiently. Partially irreversible coil implantation
leads to parenchymal compression while irreversible LVR with thermal vapor or sealants induce an
inflammatory reaction. Targeted lung denervation ablates parasympathetic pulmonary nerves in
COPD for sustainable bronchodilation, and liquid nitrogen metered cryospray destroys hyperplastic
goblet cells and excessive submucous glands in the central airways to induce mucosal regeneration in
chronic bronchitis.

Conclusion:
The best-examined bronchoscopic LVR method is the valve therapy. The data from the
other modalities are still limited. Further studies are required to select the patients that will optimally
benefit from a particular treatment and to predict and treat the procedure-related complications.
Equibiotic-GI Consumption Improves Intestinal Microbiota in Subjects with Functional Dyspepsia
Authors: Palacios-González Berenice , Meraz-Cruz Noemí , Valdez-Palomares Fernanda , Nambo-Venegas Rafael 
Published: February 2019

Background:At present, the interpretation of any dysfunction by pathogenic microbial colonization of the digestive tract can be considered as the rupture of the microbiotic balance in the injured or infected area. Phytodrugs with useful properties to balance the intestinal microbiota equibiotics represent an alternative recently proposed by the Medicinal Plant Research Company Phytomedicamenta S.A. The Equibiotic-GI® is a phytodrug developed as a combination of two plant extracts, obtained from the leaves of Psidium guajava L, (Myrtaceae) and the roots of Coptis chinensis Franch. (Racunculaceae). Both plants used traditionally for the treatment of several gastrointestinal disorders.Objective:The aim of the current study was to assess the effect of Equibiotic-GI® suspension on intestinal microbiota of subjects with functional dyspepsia.Methods:An open-label study performed in 8 adult subjects with functional dyspepsia receiving orally 20 mL of the suspension, daily for two weeks. Fecal samples were collected at baseline and the end of treatment for assessing gut microbiota composition by sequencing the V3-V4 region of the 16S rRNA gene.Results:Equibiotic-GI modified the Bacteriodetes/Firmicutes proportion increasing the richness of the microbiota composition and Rikenellaceae and Alistipes abundance.Conclusion:Together with the improvement in the gastrointestinal symptomatology after the consumption of the product, the present study is the first clinical demonstration of the capacity of the Equibiotic-GI® to restore and balance the intestinal microbiota.
Predictive Value of Osteoprotegerin for Detecting Coronary Artery Calcification in Type 2 Diabetes Mellitus Patients in Correlation with Extent of Calcification Detected by Multidetector Computed Tomography
Authors: Ahmed Sahar , Sobh Rasha 
Published: February 2019

Background:Osteoprotegerin (OPG) is a tumor necrosis factor receptor super-family member. It specifically acts on bone by increasing bone mineral density and bone volume. Recent studies have evidenced its close relation to the development of atherosclerosis and plaque destabilization. Elevated OPG level has also been associated with the degree of coronary calcification in the general population and it has been considered to be a marker of coronary atherosclerosis.Objective:The aim of this study was to determine the relation between OPG levels and Coronary Artery Calcification score (CACs) in Type 2 diabetic patients in comparison to healthy controls.Methods:Our study included 45 type 2 diabetic patients (mean age 51.7 years; 51.1% male) without evidence of previous CVD and 45 healthy age and sex matched subjects as control. All participants were subjected to full history, full examination and lab investigations. Serum OPG concentration was measured by an enzyme-linked immunosorbent assay (ELISA) and CAC imaging was performed using non contrast Multi detector CT of the heart.Results:Significant CAC (<10 Agatston units) was seen in 23 patients (51.11 %).:OPG was significantly high in diabetic patients in comparison to controls with mean 12.9±5.7 pmol/l in cases, and 8.6±0.5 pmol/l in controls (P value < 0.001).:The Coronary Artery Calcification Score (CACS) was positively correlated with age and duration of diabetes. The OPG was positively correlated with age, fasting blood sugar and duration of diabetes. The CACS showed a significantly positive correlation with OPG.Conclusion:Findings suggested that increasing in serum OPG was consistent with CAC and could be used for the early diagnosis of subclinical atherosclerosis.
Contact Allergy in Children with Atopic Dermatitis: A Retrospective Study
Authors: Romita Paolo , Foti Caterina , Stingeni Luca , Hansel Katharina , Magrone Thea , Belsito Donald V. , Bonamonte Domenico 
Published: February 2019

Background:
The relationship between atopic dermatitis and allergic contact dermatitis is
frequently debated, particularly in children. The impaired skin barrier of atopic subjects can facilitate
the penetration of exogenous agents and its mutations in the filaggrin gene might be implicated in an
increased risk to develop contact dermatitis. Moreover, atopic children are protractedly exposed to
chemical substances contained in skin care products from an early age.

Patients And Methods:
The aim of this retrospective study is to determine if atopic children are more
prone to allergic contact dermatitis and which substances are more frequently related to this disease.
From 2014 to 2016, a total of 268 children under 14 years with a history of eczematous dermatitis, of
whom 141 (52.6%) were affected, and 127 (47.4%) were not affected by AD, underwent patch testing
with the baseline S.I.D.A.P.A standard series.

Results:
Based on the results of our study, the prevalence of contact allergy in atopic children is comparable
to that noted in non-atopic children. The most frequent causes of contact allergy in children are
fragrances, and their prevalence is significantly higher in atopic children (19.9%) than in non-atopic
ones, (11.8%; p < .05).

Conclusion:
Our study highlights the importance of patch testing in atopic children for continuously
monitoring the trends and changes of contact allergies that are a common disease and is even significantly
increasing for some allergens, as fragrances. We may speculate that the protracted use of skincare
products, associated with the impaired skin barrier of atopic children, enhances the risk of sensitization
to the ingredients of these products.
A Partition Based Framework for Large Scale Ontology Matching
Authors: Patel Archana , Jain Sarika 
Published: February 2019

:Large amount of data coming from different sources and formats is available on the web which generates heterogeneity problem. Semantic web technologies play an important role for collecting, merging, matching and aggregating big data from heterogeneous resources by determining the semantic correspondence between the entities. However, achieving good efficiency is major challenge for large scale ontology matching task.Objective:We propose a PBOM framework for coping with the large scale ontology matching problem.Methods:Our proposal first selects the source ontology and calculates the similarity of concepts within source ontology by using Lin measure. We use clustering algorithm for partition of the source ontology, obtained clusters of source ontology then used to divide the target ontology. During matching process, we run matchers from the pool of the matchers over each clusters. We aggregate the result of element level matchers and structure level matchers according to weighted sum aggregation. Each cluster is executed in its processor in parallel with other clusters.Results:We have presented step wise execution of proposed approach over one cluster of source and target ontology. The evaluation of our framework is performed by OAEI datasets of bibliographic benchmark 2014, biomedical track 2015 and anatomy 2016.Conclusion:Results show that, the performance of our approach is better in term of F-measure. The combination of clustering algorithm and parallel processing reduces the memory space and time complexity of matching process.
Activation of GLP-1 and Glucagon Receptors Regulates Bile Homeostasis Independent of Thyroid Hormone
Authors: Patel Vishal J. , Joharapurkar Amit A. , Kshirsagar Samadhan G. , Sutariya Brijesh K. , Patel Maulik S. , Bahekar Rajesh H. , Jain Mukul R. 
Published: February 2019

Background:Balanced coagonists of glucagon-like peptide-1 (GLP-1) and glucagon receptors are emerging therapies for the treatment of obesity and diabetes. Such coagonists also regulate lipid metabolism, independent of their body weight lowering effects. Many actions of the coagonists are partly mediated by fibroblast growth factor 21 (FGF21) signaling, with the major exception of bile homeostasis. Since thyroid hormone is an important regulator of bile homeostasis, we studied the involvement of thyroid hormone in coagonist-induced changes in lipid and bile metabolism.Methods:We evaluated the effect of a single dose of coagonist Aib2 C24 chimera2 at 150 to 10000 µg/kg on tetraiodothyronine (T4) and triiodothyronine (T3) in high-fat diet-induced obese (DIO) mice and chow-fed mice. Repeated dose treatment of coagonist (150 µg/kg, subcutaneously) was assessed in four mice models namely, on lipid and bile homeostasis in DIO mice, propylthiouracil (PTU)-treated DIO mice, methimazole (MTM)-treated DIO mice and choline-deficient, L-amino acid-defined, highfat diet (CDAHFD)-induced nonalcoholic steatohepatitis (NASH).Results:Single dose treatment of coagonist did not alter serum T3 and T4 in chow-fed mice and DIO mice. Coagonist treatment improved lipid metabolism and biliary cholesterol excretion. Chronic treatment of GLP-1 and glucagon coagonist did not alter serum T3 in hypothyroid DIO mice and CDAHFDinduced NASH. Coagonist increased serum T4 in DIO mice after 4 and 40 weeks of treatment, though no change in T4 levels was observed in hypothyroid mice or mice with NASH.Conclusion:Our data demonstrate that coagonist of GLP-1 and glucagon receptors does not modulate bile homeostasis via thyroid signaling.