bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENINGKATAN PRESTASI BELAJAR MAHASISWA MELALUI PENDEKATAN SAVI PADA MATA KULIAH CURRICULUM AND MATERIAL DEVELOPMENT
Authors: Hasnah Yenni , Dewi Ratna Sari 
Published: December 2018

Penelitian ini merupakan Penelitian Tindakan Kelas (PTK) yang bertujuan untuk menganalisis efektifitas penerapan pendekatan Somatis, Auditori, Visual, dan Intelektual (SAVI) dalam meningkatkan prestasi belajar mahasiswa pada Mata Kuliah<em>Curriculum and Material Design Development (CMD)</em>. PTK tersebut dilaksanakan dalam tiga siklus melalui pendekatan kualitatif-kuantitatif untuk mendapatkan data penelitian. Subjek penelitian adalah mahasiswa Program Studi Pendidikan Bahasa Inggris FKIP UMSU. Data kuantitatif diperoleh melalui pemberian tes berupa pemahaman konsep kurikulum dan pengembangan desain materi pembelajaran, sedangkan data kualitatif didasarkan pada hasil observasi aktivitas mahasiswa dan dosen dalam pembelajaran. Hasil analisis data menunjukkan bahwa prestasi belajar mahasiswa mengalami peningkatan pada setiap siklusnya dengan tingkat keberhasilan 24,24% pada siklus I, 51,52 % pada siklus II, dan mencapai 87,89% pada siklus III. Dengan demikian dapat disimpulkan bahwa pendekatan SAVI dapat meningkatkan prestasi belajar mahasiswa, khususnya dalam pembelajaran<em>CMD.</em>
Macromodelos odontológicos impressos em 3D como recurso complementar ao ensino em escultura dentária
Authors: De Oliveira Souza Andreia , Peruzzo Daiane Cristina , França Fabiana Mantovani Gomes , De Oliveira Arlete Maria Gomes , Kantovitz Kamilla Rosamilia 
Published: December 2018

A diversificação das práticas pedagógicas visa o aprimoramento do processo de ensino. Novas metodologias, que favoreçam o interesse dos alunos e que proporcionem melhor compreensão, podem ser ferramentas importantes no processo ensino-aprendizagem. O objetivo desse estudo foi avaliar a percepção dos estudantes sobre o uso de macromodelos odontológicos, confeccionados com impressora 3D, como recurso complementar de ensino na disciplina Escultura Dentária, no curso de graduação em Odontologia da FACIPLAC. A amostra foi composta por 44 estudantes, matriculados no quinto período. Foram produzidos 44 conjuntos com quatro macromodelos, sendo um incisivo central, um canino, um primeiro pré-molar e um primeiro molar, todos superiores, confeccionados em material plástico colorido e resistente. Os conjuntos foram entregues aos estudantes no início de cada aula e utilizados para demonstração das estruturas anatômicas, visando à melhor fixação do conhecimento, sendo recolhidos posteriormente. Ao final do semestre letivo foi aplicado um questionário relativo ao aproveitamento do uso dos macromodelos, com resposta de 38 estudantes. Os resultados indicam que o uso dos macromodelos foi válido como recurso facilitador da compreensão da técnica de escultura dentária; contribuindo com o processo de aprendizagem em comparação ao uso de diapositivos; destacando as dificuldades no aprendizado; auxiliando na sedimentação dos conceitos das formas geométricas das estruturas dentárias. Os estudantes indicam seu uso, contudo consideram que não substitui a demonstração prática pelo docente.
WORLD AND DOMESTIC EXPERIENCE OF BIOETHANOL PRODUCTION
Authors: Dolinskyi А.A. , Obodovych O. M. , Sydorenko V.V. 
Published: December 2018

The paper presents an overview of bioetanol production technologies. It is noted that world fuel ethanol production in 2017 amounted to more than 27,000 million gallons (80 million tons). Eight countries, namely the USA, Brazil, the EU, China, Canada, Thailand, Argentina, India, together produce about 98% of bioethanol. In Ukraine, the volume of bioethanol production by alcoholic factories in recent years has been gradually increasing and amounted to 2,992.8 ths. dal in 2017. The production of ethanol as an additive to gasoline, with regard to the raw materials used, as well as the corresponding technologies, is historically divided into three generations. The first generation of biofuels produced from food crops rich in sugar or starch is currently dominant.
Production of advanced biofuels from non-food crop feedstocks is limited. Output is anticipated to remain modest in the short term, as progress is needed to improve technology readiness. The main stages of bioethanol production from lignocellulosic raw materials are pre-treatment, enzymatic hydrolysis and fermentation. The pre-treatment process aims to reduce of sizes of raw material particles, provision of the components exposure (hemicellulose, cellulose, starch), provision of better access for the enzymes (in fermentative hydrolysis) to the surface of raw materials, and reduction of crystallinity degree of the cellulose matrix. The pre-treatment process is a major cost component of the overall process. The pre-treatment process is highly recommended as it gives subsequent or direct yield of the fermentable sugars, prevents premature degradation of the yielded sugars, prevents inhibitors formation prior hydrolysis and fermentation, lowers the processing cost, and lowers the demand of conventional energy in general. From the perspective of efficiency, promising methods of pre-treatment of lignocellulosic raw materials to hydrolysis are combined methods combining mechanical, chemical and physical mechanisms of influence on raw materials. One method that combines several physical effects on a treated substance is the discrete-pulsed energy input (DPIE) method. The DPIE method can be applied in the pre- treatment of lignocellulosic raw material in the technology bioethanol production for intensifying the process and reducing energy consumption. Ref. 15, Fig. 2.
APLIKASI E-COMMERCE DENGAN METODE THEORY OF PLANNED BEHAVIOR DALAM BISNIS PENJUALAN (STUDI KASUS TOKO-TOKO DI WONOSOBO)
Authors: Hasanah Nur 
Published: December 2018

Masih banyaknya toko yang belum memanfaatkan falisitas internet, penjualan barang dagang masih bersifat konvensional, hal ini sangat berpengaruh terhadap penjualan produk hingga omzet yang didapat. Penerapan e-commerce merupakan hal yang penting dalam dunia usaha mengingat kebutuhan menyesuaikan perkembangan dunia luas sehingga mengharuskan kita agar terus berfikir secara kretif dalam mengembangkan usaha di dunia usaha Kegiatan menjual dan membeli menggunakan media internet serign dikenal sebagai e-commerce. kesuksesan penjualan pada e-commerce ini sanat tergantung akan implementasi electronic commerce technology.
Mendapatkan hasil berupa tingkat kepentingan atas implementasi e-commerce dalam bisnis penjualan dengan objek penelitian beberapa toko yang ada di Wonosobo, selain itu juga bertujuan memberikan rekomendasi kepada toko yang belum menerapkan sistem e-commerce, agar setelah penelitan dilakukan bisa memanfaatkan teknologi internet yaitu menerapkan sistem ecommerce.
Penelitian ini menerapkan Theory of Planned Behavior, dimana variabel yang mentukan intense untuk penentuan apa perilaku selanjutnya, yaitu Norma Subjektif (subjective norm) , sikap (attitude toward the behavior), dan kendali perilaku(perceivd behavior control). Variabel dependen berupa Usage Behavior dengan Intention to Use sebagai variabel independennya. Dependent Variable berikutnya yaitu niat menggunakan(Intention to Use) dengan independent variablenya adalah Subjective Norms, Sikap Atas Perilaku dan Kendali Perilaku.
Analisis data menggunakan uji regresi dengan pengecekan antara variabel independen dan variabel dependen. Akan dihasilkan model persamaan matematis dengan penggunaan uji statistik sehingga akan diketahui tingkat pengaruh independent variable atas dependent variable.
L’enseignement, l’apprentissage, l’enseignement/apprentissage de la lecture de 1994 à 2016
Authors: Briquet-Duhazé Sophie 
Published: December 2018

Pour apprendre à lire, il est nécessaire que l’enfant comprenne le principe alphabétique (caractérisant toutes les langues) consistant à faire correspondre une suite de lettres d’un mot lu en une suite de sons qui lui correspond. Plus cette procédure est automatisée, plus l’élève peut porter ses efforts sur la compréhension du texte lu. Lire c’est donc comprendre un texte lu. L’objectif de cette note de synthèse est d’établir un répertoire d’une centaine de recherches portant sur trois catégories : l’enseignement, l’apprentissage puis l’enseignement-apprentissage de la lecture, entre 1994 et 2016. Les pratiques au CP, la compréhension sont au cœur de l’enseignement de la lecture tout comme la recherche de son efficacité. L’apprentissage de la lecture s’oriente progressivement vers les difficultés en concentrant les recherches sur les prédicteurs. Les travaux reliant enseignement et apprentissage de la lecture quittent le terrain socio-économique pour se centrer sur des méta-analyses ou bien des recherches ciblées incluant l’analyse des pratiques enseignantes et la littératie.
Travail collectif et individuel des enseignants sur leurs ressources le cas d’un collectif dédié aux langues
Authors: Beauné Aurélie 
Published: December 2018

La recherche présentée dans cette contribution a été conduite dans le cadre du projet ReVEA (Ressources vivantes pour l’enseignement et l’apprentissage). L’analyse porte sur une partie des données recueillies pour l’étude de l’activité d’un collectif dédié à l’enseignement des langues. Le cadre de référence mobilisé renvoie notamment à la théorie des communautés de pratiques : comment caractériser les rapports entre activités individuelles et collectives concernant les ressources éducatives ? Quels contrastes s’observent dans les activités individuelles au regard des types de participation aux activités collectives ? L’analyse menée à partir des concepts de participation « périphérique légitime » et « à part entière » a notamment permis d’attirer l’attention sur les liens entre la réification de ressources pour le collectif et le processus de sélection de ressources mis en œuvre individuellement.
L’EPS au prisme des disciplines : polysémie et pluralité de l’interdisciplinarité (1981-2015)
Authors: Le Roy Dimitri , Trohel Jean , Attali Michaël 
Published: December 2018

« Interdisciplinarité, pluridisciplinarité, transdisciplinarité » : trois notions différentes, aujourd’hui à la mode dans le milieu scolaire et fréquemment usitées sans discernement par les enseignants. Si les réformes actuelles les placent au cœur des débats, l’appréhension des croisements disciplinaires est ancienne et surtout plurielle. L’Éducation physique et sportive (EPS) est régulièrement conviée à ce type de démarche pédagogique et constitue, à ce titre, un bon analyseur des rapports des enseignants à l’égard de ces concepts. Par l’intermédiaire d’une analyse de contenu (Bardin, 2003) de 1981 à 2015, de la revue professionnelle de référence – Éducation physique et sport ( EP. S ) – nous signifions que ce périodique accorde une place croissante aux croisements disciplinaires en les associant à des enjeux éducatifs forts. Si la pluridisciplinarité est présentée comme facilitant la formation globale, l’interdisciplinarité optimiserait l’instruction et la transdisciplinarité l’éducation de l’élève.
Cosmopolitisme et politiques publiques : New York Ville Providence (1933‑1975)
Authors: Pouzoulet Catherine 
Published: December 2018

Le New York du New Deal, où l’administration La Guardia engage sa ville dans la construction à l’échelle municipale d’un modèle de social-démocratie que l’on peut qualifier de ville providence, démontre l’importance de politiques publiques locales pour entretenir une tradition culturelle de cosmopolitisme. Ces choix politiques qui traitaient à égalité tous les espaces urbains n’ont pas survécu au passage après 1975 à une économie financiarisée.
Adölesanlarda varyant anjina: Kardiyak bilgisayarlı tomografinin kullanımı ve literatür taraması
Authors: ALP Hayrullah , KELEŞ ALP Esma , ELMACI Ahmet Midhat 
Published: December 2018

Göğüs ağrısı çocuklarda ve özellikle de adölesanlarda sık
bir şikâyet olup çoğunlukla kalp dışı nedenlidir. Varyant anjina çocuklarda
nadir görülen kalp kaynaklı göğüs ağrısı nedenlerinden birisidir. Varyant
anjina erişkinlerde iyi tanımlanmış olmasına rağmen, adölesanlardaki göğüs
ağrısının nadir bir nedenidir. Bu makalede varyant anjina tanısı konulan üç adölesan
bildirilmiş olup varyant anjinanın tanısında kardiyak bilgisayarlı tomografinin
kullanımı ve tedavisi literatür eşliğinde ayrıntılı olarak tartışılmıştır.
İnfertil Bir Erkekte “De La Chapelle” Sendromu: Olgu Sunumu
Authors: TEMEL Muhammed Cihan , EDİZ Caner , AKAN Serkan , YILMAZ Ömer 
Published: December 2018

46 XX erkek sendromu çok nadir görülen bir hastalık olup,
ilk olarak 1964 yılında De La
Chapelle ve arkadaşları tarafından tanımlanmıştır1. Hastalar normal
genital yapıdan ambiguus genitalya kadar değişebilen bir genital görünüme sahip
olabilirler2.
Y kromozomundaki cinsiyet belirleyen SRY genini içeren bir parçanın X
kromozomuna translokasyonuyla geliştiği düşünülen bir hastalıktır. Genellikle
erkek fenotipinde gelişme olur ve Y kromozom eksikliğine bağlı testiküler
yetmezlik tablosu gelişir2. Otuz dört yaşında 10 aydır evli bir erkek hasta
infertilite nedeniyle polikliniğimize başvurdu. Fizik muayenesinde bilateral
testislerin atrofik olduğu izlendi. Hastada hipergonadotropik hipogonadizm ve
azoospermi saptandı. Hastanın karyotip analizi 46,XX olarak saptandı ve X
kromozomunda SRY sinyali mevcuttu. Moleküler analizde hastanın Y kromozomunun p
kolunun SRY ve ZFY bölgelerini içerdiği saptandı. Ayrıca AZFa, AZFb, AZFc
delesyonu bulunduğu görüldü. Bu hastalarda spermatogenez olmadığından testis
biyopsisi ve spermiogram uygun değildir8. Hastalıkta başlıca tedavi testosteron
replasmanıdır. Ayrıca profesyonel bir genetik danışmanlık için hastanın
yönlendirilmesi uygundur. De La
Chapelle sendromu, infertilite ile polikliniğe başvuran
bilateral testis atrofisinin eşlik ettiği primer hipogonadizmli hastaların
ayırıcı tanısında akılda tutulması gereken bir hastalıktır.
Dosimetric effects of the kV based image‐guided radiation therapy of prone breast external beam radiation: Towards the optimized imaging frequency
Authors: Xu Huijun , Lee Sung‐Woo , Guerrero Mariana , Yi Byong Yong , Chen Shifeng , Becker Stewart J. , Chung Heeteak , Cheston Sally B. 
Published: December 2018

AbstractPurposeFor prone breast treatment, daily image‐guided radiation therapy (IGRT) allows couch shifting to correct breast position relative to the treatment field. This work investigates the dosimetric effect of reducing kV imaging frequencies and the feasibility of optimizing the frequency using patient anatomy or their first 3‐day shifts.MethodThirty‐seven prone breast patients who had been treated with skin marker alignment followed by daily kV were retrospectively analyzed. Three IGRT schemes (daily‐kV, weekly‐kV, no‐kV) were simulated, assuming that fractions with kV imaging deliver a dose distribution equivalent to that in computed tomography (CT) planning, whereas other fractions yield a dose distribution as recreated by shifting the CT plan isocenter back to its position before the couch shift was applied. Treatment dose to targets (breast and lumpectomy cavity [LPC]) and organs at risks (OAR)s (heart, ipsilateral lung) in different schemes were calculated. Patient anatomy information on CT plans and first 3‐day couch shift data were analyzed to investigate whether these factors could guide imaging scheme optimization.ResultsWhen kV imaging frequency was reduced, the percentage dose changes (δD) for breast and LPC objectives (average <1%) were smaller than those for heart and lung (average 28%–31% for Dmean). In general, the δD of no‐kV imaging was approximately that of weekly kV imaging × a factor of 1.2–1.4. Although most dose objectives were not affected, the potential higher heart dose may be of concern. No strong correlation was found between δD for different kV frequencies and patient anatomy size/distance or the first 3‐day couch shift data.ConclusionsDespite resulting in lower imaging dose, time, cost, and similar target coverage, a reduction in kV imaging frequency may introduce higher heart complication risk. Daily kVs are needed more in left‐sided breast patients. A less frequent imaging schedule, if considered, cannot be individually optimized using CT anatomic features or early shift data.
Synthesis of Unsymmetrical Aromatic Azoxy Compounds by Silver‐Mediated Oxidative Coupling of Aromatic Amines with Nitrosoarenes
Authors: Ding Weijie , Xu Shengshi , Yu Xiaochun , Wang Shun 
Published: December 2018

AbstractA silver(I) oxide‐mediated synthesis of unsymmetrical aromatic azoxy compounds has been successfully achieved, wherein oxidative coupling reactions between aromatic amines and nitrosoarenes take place in ethanol under air. This reaction has very high economic value because silver(I) oxide is the only oxidant required and no other additive is needed. The resulted silver particles can be easily recovered, while the only other byproduct is water. This new procedure is compatible with various functional groups and proceeds under mild reaction conditions.magnified image
Attitudes, Behavior, and Comfort of Emergency Medicine Residents in Caring for LGBT Patients: What Do We Know?
Authors: Moll Joel , Krieger Paul , Heron Sheryl L. , Joyce Cara , Moreno‐Walton Lisa 
Published: December 2018

AbstractBackgroundAlthough lesbian, gay, bisexual, and transgender (LGBT) patients are ubiquitous in emergency medicine (EM), little education is provided to EM physicians on LGBT health care needs and disparities. There is also limited information on EM physician behavior, comfort, and attitudes toward LGBT patients. The objective of this study was to assess EM residents behavior, comfort, and attitudes in LGBT health.MethodsAn anonymous survey link was sent to EM programs via the Council of Residency Director listserv. The primary outcome of the 24‐item descriptive survey was the self‐reported comfort levels and self‐reported practice in LGBT health care. Secondary outcomes included individual comfort toward LGBT colleagues and patients who are LGBT, and the frequency of colleagues making discriminatory statements toward LGBT patients and staff in the emergency department setting. Associations between personal and program demographics and survey responses were also examined.ResultsThere were 319 responses The majority of respondents were male (63.4%), Caucasian (69.1%), and heterosexual (92.4%). A sizeable minority of respondents felt histories and physical examinations were more challenging for lesbian, gay, or bisexual patients (24.6%) and more so for transgender patients (42.6%). Most residents do not ask patients to identify sexual orientation when presenting with abdominal or genital complaints (63%). Discriminatory LGBT comments were reported from both fellow residents (16.6%) and faculty (10%). A total of 2.5% of respondents were uncomfortable with other LGBT physicians, and 6% did not agree that LGBT patients deserve the same quality care as others.ConclusionA number of residents find caring for LGBT patients more challenging than heterosexual patients. Even with professed comfort with LGBT health care, most residents report taking incomplete sexual histories that may affect patient care. Attitudes toward LGBT patients are mainly, but not completely, positive in this cohort.
Comparative Risk of Venous Thromboembolism in Rheumatoid Arthritis Patients Receiving Tofacitinib Versus Those Receiving Tumor Necrosis Factor Inhibitors: An Observational Cohort Study
Authors: Desai Rishi J. , Pawar Ajinkya , Weinblatt Michael E. , Kim Seoyoung C. 
Published: December 2018

ObjectiveTo evaluate the risk of venous thromboembolism (VTE) in rheumatoid arthritis (RA) patients receiving tofacitinib versus those receiving tumor necrosis factor (TNF) inhibitors.MethodsRA patients who were initiating treatment with tofacitinib or a TNF inhibitor and had not previously received any biologic agent or tofacitinib were identified from the Truven MarketScan database (2012–2016) or Medicare claims (parts A, B, and D) database (2012–2015). Patients were followed up until treatment discontinuation, treatment switch, insurance disenrollment, or administrative censoring. The outcome of VTE was identified using inpatient claims for pulmonary embolism or deep vein thrombosis. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were determined using a Cox proportional hazards model after accounting for confounding through propensity score–based fine‐stratification weighting. HRs were pooled across databases using the inverse variance meta‐analytic method.ResultsA total of 34,074 RA patients (mean age 50 years; 5.6% tofacitinib initiators) and 17,086 RA patients (mean age 71 years; 5.8% tofacitinib initiators) were identified from the Truven and Medicare databases, respectively. The crude incidence rates of VTE per 100 person‐years were 0.60 (95% CI 0.26–1.19) and 0.34 (95% CI 0.27–0.41) in Truven and 1.12 (95% CI 0.45–2.31) and 0.92 (95% CI 0.76–1.11) in Medicare for patients receiving tofacitinib and patients receiving TNF inhibitors, respectively. Propensity score–adjusted HRs showed no significant differences in the risk of VTE between tofacitinib‐treated and TNF inhibitor–treated patients in either database, with a pooled HR of 1.33 (95% CI 0.78–2.24).ConclusionOccurrence of VTE in a total of 50,865 RA patients initiating treatment with tofacitinib or a TNF inhibitor was infrequent (<1 per 100 person‐years). We observed a numerically higher, but statistically nonsignificant, risk of VTE in RA patients receiving tofacitinib versus those receiving TNF inhibitors.
Biosensor‐assisted engineering of a high‐yield Pichia pastoris cell‐free protein synthesis platform
Authors: Aw Rochelle , Polizzi Karen M. 
Published: December 2018

AbstractCell‐free protein synthesis (CFPS) has recently undergone a resurgence partly due to the proliferation of synthetic biology. The variety of hosts used for cell‐free extract production has increased, which harnesses the diversity of cellular biosynthetic, protein folding, and posttranslational modification capabilities available. Here we describe a CFPS platform derived from Pichia pastoris, a popular recombinant protein expression host both in academia and the biopharmaceutical industry. A novel ribosome biosensor was developed to optimize the cell extract harvest time. Using this biosensor, we identified a potential bottleneck in ribosome content. Therefore, we undertook strain engineering to overexpress global regulators of ribosome biogenesis to increase in vitro protein production. CFPS extracts from the strain overexpressing
FHL1 had a three‐fold increase in recombinant protein yield compared with those from the wild‐type X33 strain. Furthermore, our novel CFPS platform can produce complex therapeutic proteins, as exemplified by the production of human serum albumin to a final yield of 48.1 μg ml
−1. Therefore, this study not only adds to the growing number of CFPS systems from diverse organisms but also provides a blueprint for rapidly engineering new strains with increased productivity in vitro that could be applied to other organisms.
Photoautotrophic synthesis of butyrate by metabolically engineered cyanobacteria
Authors: Lai Martin J. , Lan Ethan I. 
Published: December 2018

AbstractDirect conversion of carbon dioxide into chemicals using engineered autotrophic microorganisms offers a potential solution for both sustainability and carbon mitigation. Butyrate is an important chemical used in various industries, including fragrance, food, and plastics. A model cyanobacterium Synechococcus elongatus PCC 7942 was engineered for the direct photosynthetic conversion of CO
2 to butyrate. An engineered
Clostridium Coenzyme A (CoA)‐dependent pathway leading to the synthesis of butyryl‐CoA, the precursor to butyrate, was introduced into
S. elongatus PCC 7942. Two CoA removal strategies were then individually coupled to the modified CoA‐dependent pathway to yield butyrate production. Similar results were observed between the two CoA removal strategies. The best butyrate producing strain of
S. elongatus resulted in an observed butyrate titer of 750 mg/L and a cumulative titer of 1.1 g/L. These results demonstrated the feasibility of photosynthetic butyrate production and expanded the chemical repertoire accessible for production by photoautotrophs.