bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quinazoline‐Based Thermally Activated Delayed Fluorecence for High‐Performance OLEDs with External Quantum Efficiencies Exceeding 20%
Authors: Li Bowen , Wang Zhiheng , Su Shi‐Jian , Guo Fengyun , Cao Yong , Zhang Yong 
Published: February 2019

AbstractThe development of new and easily available acceptor moieties for further expansion of the thermally activated delayed fluorecence (TADF) family becomes imperative. In this study, new donor–acceptor TADF materials are designed and synthesized via introducing quinazoline unit as a simple and efficient acceptor for the first time. This is also a typical example of efficient spin–orbit charge transfer coupled between the acceptor triplet (3LEA) and charge transfer singlet (1CT). The small 3LE–1CT gap of 0.09–0.22 eV plays a key role in these four emitters leading to the obvious TADF properties. Moreover, these materials exhibit green to yellow‐green emission and high photoluminescence quantum yield of 67.5–81.0% in the 1,3‐bis(N‐carbazoly)benzene (CBP) host. Organic light‐emitting diodes using the doped emitters exhibit high external quantum efficiency of 16.0–20.5%.
Trifunctional Electrocatalysis on Dual‐Doped Graphene Nanorings–Integrated Boxes for Efficient Water Splitting and Zn–Air Batteries
Authors: Hu Qi , Li Guomin , Li Guodong , Liu Xiufang , Zhu Bin , Chai Xiaoyan , Zhang Qianling , Liu Jianhong , He Chuanxin 
Published: February 2019

AbstractDespite the exciting achievements made in synthesis of monofunctional electrocatalysts for oxygen reduction reaction (ORR), oxygen evolution reaction (OER), or hydrogen evolution reaction (HER), it is challenging to develop trifunctional electrocatalysts for both ORR/OER/HER. Herein, N, O‐codoped graphene nanorings‐integrated boxes (denoted NOGB) are crafted via high‐temperature pyrolysis and following acid etching of hybrid precursors containing polymers and Prussian blue analogue cubes. The electrochemical results signified that the resulting NOGB‐800 (800 refers to pyrolysis temperature) is highly active for trifunctional electrocatalysis of ORR/OER/HER. This can be reasonably attributed to the advanced nanostructures (i.e., the hierarchically porous nanostructures on the hollow nanorings) and unique chemical compositions (i.e., N, O‐codoped graphene). More attractively, the rechargeable Zn–air battery based on NOGB‐800 displays maximum power density of 111.9 mW cm−2 with small charge–discharge potential of 0.72 V and excellent stability of 30 h, comparable with the Pt/C+Ir/C counterpart. The NOGB‐800 could also be utilized as bifunctional electrocatalysts for overall water splitting to yield current density of 10 mA cm−2 at a voltage of 1.65 V, surpassing most reported electrocatalysts. Therefore, the NOGB‐800 is a promising candidate instead of precious metal–based electrocatalysts for the efficient Zn–air battery and water splitting.
Hydrated Intercalation for High‐Performance Aqueous Zinc Ion Batteries
Authors: Shin Jaeho , Choi Dong Shin , Lee Hyeon Jeong , Jung Yousung , Choi Jang Wook 
Published: February 2019

AbstractAqueous zinc ion batteries (AZIBs) are steadily gaining attention based on their attractive merits regarding cost and safety. However, there are many obstacles to overcome, especially in terms of finding suitable cathode materials and elucidating their reaction mechanisms. Here, a mixed‐valence vanadium oxide, V6O13, that functions as a stable cathode material in mildly acidic aqueous electrolytes is reported. Paired with a zinc metal anode, this material exhibits performance metrics of 360 mAh g−1 at 0.2 A g−1, 92% capacity retention after 2000 cycles, and 145 mAh g−1 at a current density of 24.0 A g−1. A combination of experiments and density functional theory calculations suggests that hydrated intercalation, where water molecules are cointercalated with Zn ions upon discharge, accounts for the aforementioned electrochemical performance. This intercalation mechanism facilitates Zn ion diffusion throughout the host lattice and electrode–electrolyte interface via electrostatic shielding and concurrent structural stabilization. Through a correlation of experimental data and theoretical calculations, the promise of utilizing hydrated intercalation as a means to achieve high‐performance AZIBs is demonstrated.
Palladium‐Catalyzed C−H Arylation of Aliphatic and Aromatic Ketones using Dipeptide Transient Directing Groups
Authors: Cheng Yaohang , Zheng Jie , Tian Chao , He Yuhang , Zhang Cong , Tan Qi , An Guanghui , Li Guangming 
Published: February 2019

AbstractKetones are ubiquitous structural motifs in chemical materials and medicinally active pharmaceutical ingredients. Transition metal‐catalyzed C−H bond functionalization is one of the most efficient tactics for diversification of ketones. Palladium‐catalyzed C−H arylation of aliphatic and aromatic ketones has been achieved utilizing an inexpensive dipeptide as a transient directing group. The tridentate coordination used in this reaction enhances the reactivity of the substrates and allows reduction of the loading of the directing group compounds to 20%. This approach allows rapid arylation of complex natural products, medicinal‐chemistry‐related scaffolds, and even remote C(sp2)−H bonds.
Standard methods for creating digital skeletal models using structure‐from‐motion photogrammetry
Authors: Morgan Brianne , Ford Andrew L.J. , Smith Martin J. 
Published: February 2019

AbstractObjectivesThis article assesses best practices for producing 3D digital cranial models through structure‐from‐motion (SfM) photogrammetry, and whether the metric accuracy and overall presentation of photogrammetric models are comparable to physical crania. It is intended to present a user‐friendly standard method of creating accurate digital skeletal models using Agisoft PhotoScan.Materials and methodsApproximately 200 photographs were taken of three different crania, and were separated into series consisting of 50, 75, 100, 150, and approximately 200 photos. Forty‐five cranial models were created using different photo series and a variety of PhotoScan settings. These models were assessed based on defined qualitative criteria, and model measurement estimates were compared with physical skeletal measurements using Bland–Altman plots.ResultsThe majority of all models (37/45) produced measurement estimates with mean differences of 2 mm or less regardless of PhotoScan settings, and therefore demonstrated high levels of agreement with the physical measurements. Models created with 150 photographs and on “high” PhotoScan settings scored the highest in terms of qualitative appearance in the shortest amount of time.DiscussionIn PhotoScan, it is recommended to create cranial models using 150 photographs and “high” settings; this produces digital cranial models that are comparable to physical crania in both appearance and proportion. SfM photogrammetry is a convenient, noninvasive, and rapid 3D modeling tool that can be used in almost any setting to produce digital models, and following the guidelines established here will ensure that these models are metrically accurate.
Stability of polyethylenimine solution‐in‐liquid paraffin emulsion for preparing polyamine microspheres with potential adsorption for ionic dyes
Authors: Huang Dengfa , Wang Feng , Zhu Jingwen , Pei Xiaomei 
Published: February 2019

AbstractA microsphere synthesized by emulsion crosslinking of polyethylenimine (PEI) was applied in the removal of ionic dyes from water. Firstly, the stability of the PEI solution‐in‐liquid paraffin emulsion was improved by using the mixture of Span‐80/Tween‐80 as the emulsifier. The optimization by 25‐1 fractional factorial design demonstrated the most stable emulsion was prepared at 0.07 g/mL of the emulsifier dosage, 6:4 (v:v) of the oil/water ratio, 20 % (wt %) of the PEI concentration, 6:1 (w:w) of the Span‐80/Tween‐80 ratio with a homogenization speed of 6000 r/min for 3 min at 25 oC. Then, the polyamine microsphere (PA‐M) was obtained by crosslinking the PEI emulsion with glutaraldehyde. The PA‐M microsphere can adsorb xylenol orange (XO) from aqueous solution with a capacity of 1169.2±12.5 mg/g. The amount of XO adsorption remained constant in the pH range of 2.0‐11.0. Adsorption kinetics analysis demonstrated that Pseudo first‐order model fit the experimental data better, indicating the overall adsorption process was controlled by ‘surface reaction’. The XO adsorption on the microsphere was due to an electrostatic interaction according to the results of ΔG evaluation. The value of separation factor suggested the XO adsorption was favorable. The used PA‐M microsphere can be regenerated and reused in adsorption/desorption operation at least 20 times.
Surface Functionalization of Magnetite Nanoparticles with Sulfonic Acid and Heteropoly Acid: Efficient Magnetically Recoverable Solid Acid Catalysts
Authors: Hosseini Mahdiyeh‐Sadat , Masteri‐Farahani Majid 
Published: February 2019

AbstractNew magnetically recoverable solid acid catalysts for acid‐catalyzed reactions were designed via the surface chemical functionalization of silica‐coated magnetite nanoparticles (SCMNPs) with sulfonic acid groups. First, the SCMNPs were covalently functionalized with 3‐aminopropyl groups to achieve Amp‐SCMNPs. Then, reaction of the Amp‐SCMNPs with 1,4‐butane sultone followed by acidification with phosphotungstic acid (HPW) or diluted sulfuric acid produced magnetically recoverable solid acid catalysts, HPW‐ampsul‐SCMNPs and H‐ampsul‐SCMNPs, respectively. Both catalysts were characterized by various physicochemical analyses such as Fourier transform infrared (FT‐IR) and inductively coupled plasma‐optical emission (ICP‐OES) spectroscopies, vibrating sample magnetometry (VSM), scanning electron microscopy (SEM), transmission electron microscopy (TEM), X‐ray diffraction (XRD), and energy‐dispersive X‐ray (EDX) analyses. Finally, the catalytic activities of the prepared catalysts were examined in the esterification of acetic acid with butanol and acetalization of benzaldehyde with ethylene glycol. Excellent catalytic efficiencies were obtained in both cases. The catalysts were consecutively recovered and reused five times without significant loss of their activities.
Combination of photoinduced fluorescence and GC–MS for elucidating the photodegradation mechanisms of diflubenzuron and fenuron pesticides
Authors: Diaw Pape A. , Mbaye Olivier M.A. , Thiaré Diene D. , Oturan Nihal , Gaye‐Seye Mame Diabou , Coly Atanasse , Le Jeune Bernard , Giamarchi Philippe , Oturan Mehmet A. , Aaron Jean‐Jacques 
Published: February 2019

AbstractDiflubenzuron (DFB) and fenuron (FEN) are benzoylurea and phenylurea pesticides, widely used in Senegal, that do not exhibit any natural fluorescence, but can be determined by means of photoinduced fluorescence (PIF) methods. Photodegradation of DFB and FEN yielded a number of fluorescent and non‐fluorescent photoproducts. For both pesticides, at least 10 photoproducts were detected and identified by gas chromatography–mass spectrometry (GC/MS). To identify the formed fluorescent DFB and FEN photoproducts, their fluorescence spectra were compared with those of standard compounds, including phenol and p‐hydroxyaniline.
Carbon dots synthesized by them‐trihydroxybenzene as the carbon source and its application on the detection of pH value
Authors: Peng Xiaoxiao , Li Chenchen , Zhang Yubing , Chen Shu , Long Yunfei 
Published: February 2019

AbstractNew carbon dots (CDs) were prepared by a microwave method usingm‐trihydroxybenzene and dilute sulphuric acid as raw materials. The as‐prepared CDs exhibited excellent water solubility and photoluminesence properties. The optimum excitation and emission wavelengths of the new CDs were at 365 nm and 465 nm, respectively. The fluorescence of the new CDs experienced remarkable changes in the presence of Britton–Robinson (BR) buffer solution with different pH values under 4°C after reacting for 70 min. In addition, a linear relationship between the logarithm of the relative fluorescence intensity ratio [lg(IF/IFo)] of CDs and the pH values of the sensing system ranging 1.81–5.72 was obtained, with a correlation coefficient of 0.9933. Thus, a sensitive and simple method to detect the pH value of solution was developed. Furthermore, the analytical application of detecting the concentration of acetic acid in vinegar was investigated. The detection values were found similar to the reference values, fully demonstrating a good linear relationship between the logarithm of the relative fluorescence intensity ratio of the CDs and the pH value of the system. Hence, the method could be used to detect the concentration of acetic acid in vinegar.
Occupational gaps 5 years after stroke
Authors: Svensson Joel S. , Westerlind Emma , Persson Hanna C. , Sunnerhagen Katharina S. 
Published: February 2019

AbstractObjectivesTo investigate the incidence and number of occupational gaps 5 years after stroke and find possible predictors and explanatory factors for increased number of experienced gaps.Material and MethodsThe participants were diagnosed with first‐time stroke in Gothenburg during 2009–2010. Medical records from their hospital stay were used to obtain baseline data. The Occupational Gaps Questionnaire and the Swedish stroke registers follow‐up questionnaire were sent out. Data from the Occupational Gaps Questionnaire were used as a dependent variable and baseline data and questions from the stroke registry were used as independent variables in logistic regression.ResultsFive years poststroke, 49.5% experienced a higher number of occupational gaps compared to a healthy reference population. Predictors for an increased number of gaps were higher age at stroke onset and a higher degree of functional dependency. Explanatory factors for an increased number of gaps in the study population were higher age at follow‐up and feelings of depression.ConclusionsOlder age at the time of stroke and functional dependency can predict an increased number of occupational gaps. Older age and feelings of depression are connected to an increased number of occupational gaps. Individuals at risk should be provided with additional interventions to reduce participation restrictions.
The impact of perceived corporate social responsibility on employee engagement: The case of Qatar
Authors: Al Amri Fatma H. , Das Amit , Ben‐Ayed Omar 
Published: February 2019

AbstractThis work investigates the role of perceived corporate social responsibility (CSR) in enhancing employee engagement (EE) in the State of Qatar. We collected survey data from local and expatriate employees of government, semigovernment, and private sector Qatari firms on their perceptions of CSR activities undertaken by their employers. The scope of CSR included activities targeted at employees, customers, the government, and society at large (social and nonsocial stakeholders). We also measured two facets of EE: organizational engagement and job engagement. We examined how these dimensions of EE are associated with employees' perception of the firm's CSR activities, controlling for the type of firm (government, semigovernment, or private) and the type of employee (local or expatriate). Our results reveal that CSR to society and CSR to employees affect organizational engagement whereas CSR to customers affects job engagement. CSR to the government is not significantly related to either aspect of EE.
Enhanced expression of ten‐eleven translocation 1 reverses gemcitabine resistance in cholangiocarcinoma accompanied by a reduction in P‐glycoprotein expression
Authors: Wang Chuanxu , Ye Hua , Zhang Lei , Cheng Yayu , Xu Shifeng , Zhang Ping , Zhang Zijie , Bai Jimin , Meng Fangkang , Zhong Lin , Shi Guangjun , Li Hao 
Published: February 2019

AbstractIncreasing evidence revealed that ten‐eleven translocation 1 (TET1) plays an important role in tumorigenesis and chemoresistance, but its functions in gemcitabine resistance in cholangiocarcinoma (CCA) remain unknown. This study aims to investigate the effect of TET1 on gemcitabine resistance in CCA and the possible effect on P‐glycoprotein (P‐gp) expression encoded by multidrug resistance (MDR) genes. We established two kinds of gemcitabine‐resistant CCA cell lines and confirmed its specific features. The expression of TET1 and P‐gp was evaluated in gemcitabine‐resistant CCA cells and their parental cells at mRNA and protein level by quantitative RT‐PCR and western blot analysis. After transfecting the gemcitabine‐resistant CCA cell lines with TET1 gene or siRNA, the cell viability test was obtained to verify the effect of TET1 on the sensitivity of CCA cells to gemcitabine. And then, the possible effect of TET1 on the expression of P‐gp was examined by western blot analysis. Xenograft tumor experiment was conducted to confirm the association between TET1 and P‐gp expression under gemcitabine chemoresistance. The associations between clinical outcomes of CCA patients with chemotherapy and TET1 expression were analyzed in 82 patients. The results showed that TET1 expression was significantly decreased, and P‐gp expression was increased in gemcitabine‐resistant CCA cells. Additionally, overexpression of TET1 augmented the sensitivity of CCA cells to gemcitabine and induced the decreased expression of P‐gp in gemcitabine‐resistant CCA cells. Furthermore, multivariate Cox regression analysis indicated that TET1 expression and TNM stage were independent risk factors (P < 0.001) for the clinical outcomes of CCA patients with chemotherapy. Additionally, Kaplan‐Meier survival and the log‐rank test showed that decreased expression of TET1 was associated with poorer prognosis of CCA patients with chemotherapy. These findings suggest that TET1 expression reverses gemcitabine resistance in CCA accompanied by a reduction in P‐gp expression. Thus, TET1 may be a promising target to overcome chemoresistance in CCA.
Daturanolide A–C, Three New Withanolides from Datura metel L. and Their Cytotoxic Activities
Authors: Wang Xiao‐Yan , He Jun , Bai Hong‐Jin , Gao Pin‐Yi , Gan He , Yang Ting , Zhang Wei‐Ku , Xu Jie‐Kun 
Published: February 2019

AbstractThree new withanolides (1–3), named as daturanolide A–C, along with six known withanolides (4–9) were isolated from the flowers of Datura metel L. Their structures with absolute configurations were elucidated by a series of spectroscopic methods, electronic circular dichroism (ECD) analyses, and X‐ray crystallography. All the isolates were evaluated for cytotoxicity against five human cancer cell lines (HCT116, U87‐MG, NCI‐H460, BGC823, and HepG2), and 6 exhibited marked cytotoxicity.
Acute lumbar polyradiculoneuropathy as early sign of methotrexate intrathecal neurotoxicity: Case report and literature review
Authors: Montejo Carmen , Navarro‐Otano Judith , Mayà‐Casalprim Gerard , Campolo Michela , Casanova‐Mollá Jordi 
Published: February 2019

Key Clinical MessageAcute paraplegia after treatment with intrathecal methotrexate requires a complete spinal cord neuroimaging as well as electrodiagnostic examination. The absence of lumbosacral F waves motor responses without demyelinating findings may indicate early direct root toxicity. Early electromyography (EMG) screening could be a valuable tool for detecting peripheral neurotoxicity.
Nivolumab and immune‐mediated colitis
Authors: Walker Heather , Brennan Paul , Groome Maximillian , Walsh Shaun , Carey Frank 
Published: February 2019

Key Clinical MessageNivolumab is associated with a number of immune‐regulated adverse events, including immune‐mediated colitis and may present following the discontinuation of treatment. Current guidance suggests lower doses of methylprednisolone; however, we described faster resolution of the patient's symptoms compared to previous reported cases, using higher dosing, thereby minimizing hospitalization.
Utility of transoral pharyngeal ultrasonography for puncture drainage of peritonsillar abscess
Authors: Hagiwara Yuta , Araga Takashi , Saito Yoshimitsu , Sasano Yoshiyuki , Tamura Yuki , Shimizu Takahiro , Hasegawa Yasuhiro 
Published: February 2019

Key Clinical MessagePuncture drainage is usually needed to treat peritonsillar abscess. However, inadvertent carotid artery puncture may result in devastating complications. Preoperative transoral carotid ultrasonography (TOCU) is useful to delineate the anatomical relationship between the abscess and carotid artery. We present a case of peritonsillar abscess illustrating the utility of TOPU for safe drainage.
Whole‐exome sequencing reveals novel USP9X variant in female fetus with isolated agenesis of the corpus callosum
Authors: Lenberg Jerica L. , Pretorius Dolores H. , Rupe Eric S. , Jones Marilyn C. , Ramos Gladys A. , Andreasen Tara S. 
Published: February 2019

Key Clinical MessageWhole‐exome sequencing in a female fetus detected a USP9X variant. This X‐linked gene was recently associated with intellectual disability and distinct pattern of malformation in females. Isolated agenesis of the corpus callosum has not been reported in association with USP9X. Identifying this variant impacted management of the subsequent pregnancy.
A mimic of tachycardia‐bradycardia syndrome in a patient with long‐standing persistent atrial fibrillation
Authors: Sairaku Akinori , Matsumoto Takeshi , Kinoshita Hiroki , Matsumura Hiroya , Oguri Naoto , Morishima Nobuyuki 
Published: February 2019

Key Clinical MessagePause following incessant tachycardia is often encountered in clinical practice. We encountered a rare arrhythmic condition mimicking tachycardia‐bradycardia syndrome. We hereby describe the step‐by‐step diagnostic process.
Use of low dose of rFVIIa (recombinant Factor VII activated) to control late bleeding after percutaneous dilational tracheostomy
Authors: Nicosia Dario , Federico Antonino , Vigna Ivan , Iozzo Pasquale , Misseri Giovanni , Cortegiani Andrea 
Published: February 2019

Key Clinical MessageIn our case, the use of a low intravenous bolus dose of rFVIIa (recombinant factor VII activated; 15‐20 mcg/kg) was effective and uneventful in controlling late postprocedural PDT bleeding associated with thrombocytopenia that cannot be corrected and after all other treatments failed.
Refractory exudative pleural effusion in patients with chronic kidney disease not receiving dialysis: A case report
Authors: Seo Hye Mi , Kim Miyeon , Kim Hyunwoo 
Published: February 2019

Key Clinical MessageAlthough exudative pleural effusion can be caused by infections, malignancies, and connective tissue diseases, we need to consider uremic pleural effusion and pleuritis in differential diagnosis of exudative lymphocyte predominant pleural effusion in patients with chronic kidney disease not receiving dialysis.
One‐Step Preparation of Cobalt‐Nanoparticle‐Embedded Carbon for Effective Water Oxidation Electrocatalysis
Authors: Wu Qian , Li Jian , Wu Tongwei , Ji Lei , Zhang Rong , Jiang Pengfei , Chen Hongyu , Zhao Runbo , Asiri Abdullah M. , Sun Xuping 
Published: February 2019

AbstractThe sluggish kinetics of the oxygen evolution reaction (OER) impedes the whole water splitting efficiency and it is thus highly desirable to develop cost‐effective OER electrocatalysts. In this Communication, we report the one‐step preparation of cobalt‐nanoparticle‐embedded carbon as a superior OER electrocatalyst with a low overpotential of 232 mV to drive a current density of 10 mA cm−2 in 1.0 M KOH. Notably, this catalyst also exhibits excellent long‐term electrochemical stability. The catalytic mechanism is also investigated by density functional theory calculations.