bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of high-intensity versus low-intensity praziquantel treatment on HIV disease progression in HIV and Schistosoma mansoni co-infected patients: a randomised controlled trial
Authors: Abaasa Andrew , Asiki Gershim , Obuku Ekii Andrew , Wanyenze Josephine , Pala Pietro , J. van Dam Govert , Corstjens Paul L.A.M. , Hughes Peter , Ding Song , Pantaleo Giuseppe , Kaleebu Pontiano , Elliott Alison M. , Kamali Anatoli 
Published: April 2019

Background: It has been hypothesised that Schistosoma co-infection exacerbates HIV progression, and hence anthelminthic intervention in co-infected individuals will delay it. We evaluated effects of high-intensity versus low-intensity praziquantel treatment of schistosomiasis on HIV disease progression among co-infected patients from fishing populations around Lake Victoria, Uganda. Methods: Between August 2012 and September 2015, we conducted an open-label randomised, controlled trial. Adults, antiretroviral therapy-naïve, CD4 counts ≥350 cells/μl, HIV and S. mansoni co-infected, were randomised 1:1 to praziquantel (40mg/kg) given quarterly (starting at enrolment) or annually (starting 12 weeks after enrolment; such that low-intensity participants were still untreated when sampled at 12 weeks). A non-randomised HIV-positive S. mansoni-negative comparison group was recruited. The primary outcome was mean change in plasma viral load at 12 and 60 weeks. Results: In total 363 participants (high-intensity 113, low-intensity 113, comparison group 137) were recruited; 96 (85.0%), 97 (85.8%) and 107 (78.1%) completed 60 weeks of follow up, respectively. Adjusting for baseline age and viral load, the geometric mean ratio (aGMR [95%CI]) viral load for high-intensity vs low-intensity groups at 12 weeks was 0.90 [0.65, 1.25] p=0.55 and at 60 weeks 1.88 [0.78, 4.53] p=0.16. Results in the comparison group were similar to trial arms. High-intensity, compared to low-intensity, treatment resulted in substantially lower S. mansoni prevalence at all follow up visits (p<0.05). Conclusions: In communities with a high burden of both S. mansoni and HIV infection, high-intensity treatment of S. mansoni does not delay HIV progression despite relevant benefit for parasite clearance. Trial registration: ISRCTN15371662 (17/11/2016)
TWÓRCA W DOBIE INTERNETU. NA PRZYKŁADACH POLSKIEJ E-LITERATURY
Authors: Winiecka Elżbieta 
Published: April 2019

Artykuł poświęcony jest prezentacji przemian mitów artysty w literaturze elektronicznej. Przedmiotem badań jest tu wyłącznie przestrzeń Internetu oraz zjawiska literackie, rozwijające się przy użyciu narzędzi cyfrowych. Autorka szuka odpowiedzi na pytanie, czy i jak funkcjonują w tej nowej technologicznej i kulturowej, a także komunikacyjnej rzeczywistości wywodzące się jeszcze z modernizmu mity literackie artysty oraz jakie nowe wzorce autorstwa pojawiają się w ich miejsce. Realizowane w przestrzeni polskiego Internetu postawy, obserwowane na przestrzeni ostatnich kilkunastu lat, autorka omawia na przykładach twórcy i teoretyka literatury Zenona Fajfera, cyberpoety i filozofa Romana Bromboszcza oraz dwóch projektów grupowych: działalności Hubu Wydawniczego Rozdzielczość Chleba (zakończonej w październiku 2018 roku) oraz utworu Piksel Zdrój, zainicjowanego i koordynowanego przez Mariusza Pisarskiego. Szkic ma charakter wstępnych ustaleń, które – także ze względu na naturę medium internetowego – podlegać muszą dalszym modyfikacjom.
ARTYSTA I MIT. WOKÓŁ TREŚCI UCZUCIOWEJ REWOLUCJI ANDRZEJA WRÓBLEWSKIEGO
Authors: Nowicka Daria 
Published: April 2019

Niniejszy artykuł koncentruje się na obecności wyobraźni mitologicznej w twórczości jednego z najwybitniejszych malarzy powojennych. Autorka podejmuje w nim próbę zdefiniowania mitu obecnego w dziełach Andrzeja Wróblewskiego powstałych w latach czterdziestych i pięćdziesiątych. Zwraca uwagę na trzy możliwe sposoby jego odczytania. Stąd omówieniom poddaje mit orficki, mit odrzuconego artysty oraz mit nowego kosmosu. Interpretacja sztuki Andrzeja Wróblewskiego skierowana jest dodatkowo na omówienie kilku problemów, między innymi: statusu jego obrazów we współczesnej krytyce, rewersów biografii artystycznej, a także języków modernizmu, jakie od lat pięćdziesiątych funkcjonują w opowieściach o malarzu.
Influence of Production Parameters on the Content of Polyphenolic Compounds in Extruded Porridge Enriched with Chokeberry Fruit (Aronia melanocarpa (Michx.) Elliott)
Authors: Oniszczuk Tomasz , Widelska Gabriela , Oniszczuk Anna , Kasprzak Kamila , Wójtowicz Agnieszka , Olech Marta , Nowak Renata , Kulesza Karolina Wojtunik- , Jóźwiak Grzegorz , Hajnos Monika Waksmundzka- 
Published: April 2019

AbstractChokeberry fruit (Aronia melanocarpa(Michx.) Elliott) is known for its antioxidant properties and generally beneficial impact on human health. The aim of the research was to produce innovative corn porridge with a different content of chokeberry fruit percentage-wise and to test it to determine the content of polyphenolic compounds, including flavonoids and individual free phenolic acids, and determine the antioxidant properties of analysed extracts. One of the objectives was also to identify the optimum porridge production parameters, including, among other things, the rotational speed of the extruder screw during the extrusion process.Obtained results showed that an increased content of chokeberry fruit in porridge enhances its antioxidant properties, as well the content of polyphenols, flavonoids, and free phenolic acids. The greatest free radicals scavenging activity by all extracts was reported after 10 minutes of the process. The results of the above study demonstrate that extruded porridge enriched with chokeberry fruit have a potential for becoming a good source of natural antioxidants, and the extrusion process at 80 rpm does not degrade the tested active compounds.
High urate concentration is associated with elevated blood pressure in schoolchildren
Authors: Reis Luiza Naujorks , Reuter Cézane Priscila , Pollo Renner Jane Dagmar , Burgos Leandro Tibiriçá , Rech Franke Silvia Isabel , Burgos Miria Suzana 
Published: April 2019

AbstractBackgroundStudies in adults have shown a relationship between high blood pressure and hyperuricemia, but few studies have investigated this association in children and adolescents. The aim of the present study was to associate urate concentration with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in schoolchildren.MethodsThis cross-sectional study used a sample of 2335 schoolchildren in basic education between 7 and 17 years old. Blood pressure was classified by percentile according to Brazilian parameters for sex and age, reclassified into two categories: normal and borderline/hypertension. Blood collection to obtain serum for urate concentration analysis was performed after a 12-h fast. Values above 5.5 mg/dL were considered hyperuricemia. Descriptive data were presented in frequency and percentage. Linear regression and Poisson regression (prevalence ratio [PR]) was used to test the association between urate concentration and blood pressure.ResultsUrate concentration was weakly associated with SBP (β: 0.05; 95% CI: 0.02–0.08) and DBP (β: 0.03; 95% CI: 0.01–0.05) z-scores. Schoolchildren with hyperuricemia had a higher prevalence of high SBP (PR: 1.12; p<0.001) and DBP (PR: 1.08; p<0.001).ConclusionsElevated urate concentration is associated with altered blood pressure in schoolchildren.
Structure and dynamics of glass-forming alloy melts investigated by application of levitation techniques
Authors: Holland-Moritz Dirk , Nowak Benedikt , Yang Fan , Meyer Andreas 
Published: April 2019

Abstract
In this work results of studies on the short-range order and on the atomic dynamics in different stable and undercooled glass-forming metallic melts are reviewed. In order to undercool the melts deeply below the melting temperature and to avoid chemical reactions of the melts with crucible materials, the samples are containerlessly processed utilizing the electromagnetic or the electrostatic levitation technique. The short-range structure of the melts is studied by neutron diffraction, while the atomic dynamics are investigated by quasielastic neutron scattering. The relationship between short-range structure and atomic dynamics is discussed within the mode coupling theory of the glass transition. We will show that taking the time- and space-averaged structural information provided by measured partial structure factors as an input, mode coupling theory is able to explain the experimental results concerning the activation energies for self-diffusion and the coupling/decoupling behavior of the self-diffusion coefficients of the different alloy components.
The Effect of Altered pH on Push-Out Bond Strength of Biodentin, Glass Ionomer Cement, Mineral Trioxide Aggregate and Theracal
Authors: Makkar Sameer , Vashisht Ruchi , Kalsi Anita , Gupta Pranav 
Published: April 2019

SummaryIntroduction Throughout the history of dentistry, a wide variety of materials such as gold-foil, silver posts, amalgam, zinc oxide eugenol, glass ionomer cements, mineral trioxide aggregate have been used as retrograde fillings. Altered pH in periapical lesions can affect push-out bond strength of these materials. The aim of this study was to evaluate the effect of altered pH on push-out bond strength of Biodentin, Glass ionomer cement (GIC), Mineral trioxide aggregate (MTA) and Theracal.Material and Methods Forty-eight dentin slices of extracted single-rooted human teeth were sectioned and their canal portion instrumented to achieve a diameter of 1.4 mm. The specimens were then assigned into the four groups (one group for each material) with 12 samples in each group. All groups were further divided into 3 subgroups (with 4 specimens in each subgroup): acidic (butyric acid buffered at pH 6.4), neutral (phosphate buffer saline solution at pH 7.4) and alkaline (buffered potassium hydroxide at pH 8.4). Samples were incubated for 4 days at 37°C in acidic, neutral or alkaline medium. Push-out bond strength was measured using a Universal Testing Machine. The slices were examined under a stereomicroscope to determine the nature of bond failure.Results GIC showed the highest bond strength (33.33MPa) in neutral and acidic medium (26.75MPa) compared to other materials. Biodentin showed the best result in alkaline medium.Conclusion Altered pH level affected push-out bond strength of root end materials. GIC demonstrated good push-out bond strength that increased with decrease of pH whereas newer materials Biodentin and Theracal showed satisfying results in altered pH.
Implant Retained Orbital Prosthesis – Case Report/ Implantatno retinirana orbitalna proteza – prikaz slučaja
Authors: Lazić Vojkan , Konstantinović Vitomir , Djordjević Igor , Mihailović Milinko 
Published: April 2019

SUMMARY
Orbital defects after tumor resection (exenteration of orbital content) have been traditionally reconstructed with adhesive-retained craniofacial prostheses, also known as epistheses. The breakthrough in rehabilitation of facial defects with implant-retained prostheses has come with development of modern silicones (vynilpolysiloxane) and bone anchorage called osseointegration. Craniofacial implant technology offers improved reconstructive options to patients. This paper describes therapeutical procedure on a patient who received craniofacial implant-retained orbital prosthesis after orbital exenteration. The patient reported excellent prosthesis handling and stability
The effect of zinc oxide based sealer on bone defects healing
Authors: Nikolić Marija , Popović Jelena , Gašić Jovanka , Barac Radomir 
Published: April 2019

Summary
Introduction Obturation as the final phase of endodontic treatment aims to provide complete hermetic filling along the entire length of the canal system from the coronal opening to the apical end. The aim of this study was to evaluate histological response of bone tissue on the implantaton of zinc oxide based material in artificially prepared defect in the mandible of rats.
Material and method For the experiment, sixteen male Wistar rats were used. Using sterile steel burs a defect was made in mandible, between the midline and mental foramen. Zinc oxide based sealer was implanted in the defects of experimental group while the defects of control group healed spontaneously. One half of animals in both groups were sacrificed after thirty days, and the second half after ninety days. Microscopic preparations consisted of the defect with surrounding bone and after processing were analysed using light microscopy.
Results The thirtieth day after implantation of the material, fibrovascular connective tissue was noted, with scant chronic inflammatory cell infiltrate. Away from the experimentally made defect, in the depth of the bone, lamellar bone with well-formed larger osteons was noted as well as enlarged Volkmann and Haversian canals. Ninety days after implantation of the material, there was no restitutio ad integrum, but intense focal remodelling of bone tissue was noted.
Conclusion Endomethasone N slowed down bone tissue healing process by showing the signs of prolonged inflammation in bone tissue in which it has been implanted. Extension of the healing process is reflected in the slow replacement of fibrovascular connective tissue with newly formed bone tissue.
Decoronation as an option for ridge preservation prior to implant placement
Authors: Dragović Miroslav , Pejović Marko , Stepić Jelena , Dragović Svetlana , Čolić Snježana 
Published: April 2019

Abstract
Decoronation is a surgical procedure based on idea of sectioning tooth crown and maintaining the root in situ with intention to preclude occurrence of severe deformities of bone and soft tissue which may aggravate later rehabilitation of patient.
The aim of this report is to present the use of decoronation in a young adult patient as a solution in order to preserve sufficient amount of bone for delayed implant placement and decrease volume of grafting material to a minimum. Obtained results showed this procedure may greatly improve anatomical conditions for implant placement while reducing invasiveness and required financial means.
On the immediate and dynamical interpretants and objects of signs
Authors: Hilpinen Risto 
Published: April 2019

AbstractIn his semiotic system Peirce distinguished between two interpretants and two objects of a sign: an immediate and a dynamical interpretant, and an immediate and a dynamical object. It is argued that Peirce’s immediate object can be interpreted a qua-object which has the dynamical object as its basis, and the dynamical interpretant consists of an interpreter’s conception of the object of the sign. Peirce semiotic system is compared with the accounts given by Frege, Husserl, Meinong, and the Stoics.
Advances in Cement Analysis and Concrete Petrography
Authors: Cong Derek , Broton Don 
Published: April 2019

Description
Learn more about new supplementary cementitious materials and recent developments in cement analysis and concrete petrography.
You’ll get 12 peer-reviewed papers that cover a broad range of subjects related to material characterizations in the construction industry, including
The papers presented in this book were part of the international symposium on Advances in Cement Analysis and Concrete Petrography held in San Diego, CA, in June 2018.
Uso y selección de las partes aéreas del algarrobo Prosopis pallida (Fabaceae) por reptiles, aves y mamíferos en Sechura (Piura – Perú)
Authors: Cruzado Jacinto Leticia , Chávez-Villavicencio César Lautaro , Charcape-Ravelo Jesús Manuel 
Published: April 2019

Prosopis pallida forma parte de los algarrobales del desierto de Sechura en el noroeste peruano. Brinda múltiples beneficios como recurso para la fauna silvestre. Siguiendo el concepto de selección de recursos, se plantea como objetivo determinar el uso y selección de las partes aéreas de P. pallida por parte de reptiles, aves y mamíferos, en el algarrobal aledaño a la laguna Ñapique (Sechura, Perú). Los datos se tomaron en seis transectos seleccionados convenientemente y se calculó la disponibilidad del árbol después de dividirlo en tres componentes, copa superior, copa inferior y tronco con ramas, a los que se añadió la sombra bajo la copa como cuarto componente por estar relacionado directamente con el árbol. Se adaptó el diseño Tipo I de Manly (la disponibilidad y uso se estiman para todos los individuos de la especie dentro del área de estudio) y se usó el Cociente de Selección de Manly para determinar la selección de los componentes del árbol por parte de la fauna. Los reptiles seleccionaron la sombra bajo la copa. Las aves y mamíferos seleccionaron el tronco y ramas. El uso y selección de los diferentes componentes de P. pallida revelan la vital importancia que tiene para la sobrevivencia de la fauna silvestre en el desierto de Sechura.
Evaluación de la capacidad bactericida de extractos vegetales de distinta polaridad de Drimys granadensis
Authors: Cuervo Salcedo Daniela , Vanegas Campo Julián , Corzo Barragán Diana , Correa Mahecha Felipe 
Published: April 2019

Empleando el método de maceración en frío y fraccionamiento con solventes de polaridad creciente, se obtuvo cuatro extractos vegetales de distinta polaridad en las hojas de Drimys granadensis: Muy apolar (MA), apolar (A), polar (P) y Muy polar (MP), los cuales se obtuvieron al utilizar hexano, cloroformo, acetona y metanol para el fraccionamiento correspondiente. Una vez se obtuvieron los extractos, se siguió el protocolo de Minimum Inhibitory Concentration test (MIC) para determinar la concentración mínima a la cual se inhibe el crecimiento bacteriano, frente a dos cepas bacterianas Gram positivas: Staphylococcus aureus y Staphylococcus epidermis; y dos Gram negativas: Klebsiella pneumoniae y Escherichia coli. Como resultado se obtuvo que la fracción polar (P) fue la más efectiva, inhibiendo el crecimiento de todas las cepas bacterianas evaluadas a partir de una concentración de 15 mg/mL.
Fen Bilimleri Öğretmen Adaylarının Eğitimde Çizgi Filmin Kullanımına İlişkin Görüşleri
Authors: BERBER Asiye , ANILAN Burcu , ODABAŞ İzel Nur , ALKAN Dilan 
Published: April 2019

Öğrencilerin
çizgi film seçiminde doğru seçimler yapabilmeleri için öğretmenler yol
gösterici olmalıdır. Araştırmamızda, fen bilimleri öğretmen adaylarının
eğitimde çizgi filmlerin kullanılmasına ilişkin görüşleri belirlenmeye
çalışılmıştır. Bu araştırmada nitel araştırma yaklaşımlarından fenomenolojiden
(olgubilim) yararlanılmıştır. Araştırmanın verileri, görüşme türlerinden yarı
yapılandırılmış görüşme ile toplanmıştır.&nbsp;
Verilerin analizinde betimsel analiz tekniği kullanılmıştır. Öğretmen
adayları,&nbsp; çizgi filmlerin seçiminde
eğlenceli ve dikkat çekici olmasına,&nbsp;
izlenilen çizgi filmlerin alt yaş gruplarında çocuğun dünyası ile onun
yaşam şeklinin biçimlendirileceği dikkate alınarak uygun konu, karakter ve
davranışları sergilemesi gerektiğine vurgu yapmışlardır.
Integrated Approach to Evaluate Rock Brittleness and Fracability for Hydraulic Fracturing Optimization in Shale Gas
Authors: Ibrahim Mohamed Mohamed , Salah Mohamed , Coskuner Yakup , Ibrahim Mazher , Pieprzica Chester , Ozkan Erdal 
Published: April 2019

Abstract
A fracability model integrating the rock elastic properties, fracture toughness and confining pressure is presented in this paper. Tensile and compressive strength tests are conducted to define the rock-strength. Geomechanical rock properties derived from analysis of full-wave sonic logs and core samples are combined to develop models to verify the brittleness and fracability indices. An improved understanding of the brittleness and fracability indices and reservoir mechanical properties is offered and valuable insight into the optimization of completion and hydraulic fracturing design is provided. The process of screening hydraulic fracturing candidates, selecting desirable hydraulic fracturing intervals, and identifying sweet spots within each prospect reservoir are demonstrated.
Do We Need an Intelligent Makeup Solution for Modern Rotary Shouldered Connections?
Authors: Teodoriu Catalin 
Published: April 2019

Abstract
The accurate makeup of Rotary Shouldered Connections (RSC) is a critical step in optimizing the connection lifetime under complex downhole conditions. The makeup torque value of RSC depends on the friction coefficient of the assembly and the lubricant, which cannot normally be individually measured or determined, so that the API RP7G gives a recommended makeup torque based upon an assumed, yet constant, friction coefficient while a certain safety margin is considered. Therefore, the field induced stress state of the connection may differ from the connection optimum torque under reference conditions. This will lead to the following consequences: the lifetime of each connection is not maximized based on its drillstring position and the torque and axial force that can be transferred through the connection is different from the technical maximum limit.
Due to the technological development, a wide spectrum of power tongs can accommodate the increasing interest in mechanized operations at the rig floor today. The importance of a torque-turn recording was stated in many papers as a good control method of the makeup process, especially for casing running applications. However, we believe that the reliability of a drill string can be improved by using feed back of torque turn recordings. State-of-the-art devices not only allow the precise mechanized makeup of connections, but they also provide sufficient data to analyze the quality of the connection make-up. The motivation behind the research is the desire to make use of the data that is already provided for the benefit of increased lifetime of the connections and the reduction of drill string failures, especially for drilling under extreme downhole conditions like long horizontal, HPHT or deep water.
This paper presents a short overview of the state-of-the-art of current technology followed by a discussion of how technological advances can be used to improve the drill string reliability. Also, the readers are challenged to find the answer to the title question: "Do we need an Intelligent Makeup Solution for Rotary Shouldered Connections?"