bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stuck between a rock and a hard place: Contrasting upward and downward effects of leaders’ ingratiation
Authors: Kim Ji Koung , LePine Jeffery A. , Chun Jae Uk 
Published: March 2018

AbstractResearch indicates that leaders who engage in upward ingratiation, a specific form of impression management, develop positive relationships with their bosses, which in turn enhances leaders’ chances of achieving success at work. However, a more complete understanding of leaders’ ingratiation requires recognition that leaders have multiple audiences and that there may be negative unintended consequences of this behavior to at least one of these audiences. Specifically, upward ingratiation may reduce subordinates’ willingness to contribute to the organization through effective performance because it diminishes relationship quality between leaders and subordinates. To explore this issue, we develop and test a multilevel model that contrasts effects of leaders’ upward ingratiation on leader‐ and subordinate‐level outcomes through the quality of social exchange in the corresponding relationship. We test our predictions by conducting a multiwave, multisource field study with a sample of 91 leaders, 91 bosses, and 215 subordinates in South Korea. Our findings reveal that upward ingratiation is positively associated with indicators of leaders’ intrinsic and extrinsic success because it enhances leader–boss exchange quality (LLX). In contrast, leaders’ upward ingratiation negatively influences subordinates’ job performance because it diminishes leader–subordinate exchange quality (LMX). We also find that subordinates’ perceptions of leaders’ political skill mitigate the negative indirect relationship between upward ingratiation and subordinates’ job performance via LMX quality, and that our hypotheses apply to ingratiation but not to other forms of impression management. We discuss the theoretical and practical implications of our findings in relation to ingratiation specifically and to impression management more generally.
NP30 stimulates Th17 differentiation through DC in Schistosomiasis Japonicum
Authors: Xu L. , Xue B. , Zhou L. , Qiu Z. , Zhang X. , Xu N. , Tang Q. , Zhu J. , Guan X. , Feng Z. 
Published: March 2018

SummaryThe murine monoclonal anti‐idiotypic antibody, NP30, is a potential vaccine candidate against Schistosoma japonicum. Previous studies have revealed that NP30 has an immunoregulatory effect, but the underlying mechanism for this effect remains unknown. This study shows that NP30 induces dendritic cell (DC) maturation and increases the production of pro‐inflammatory cytokines. The expression of CD86 and MHC II was upregulated in DCs following stimulation with NP30 in vitro. Moreover, NP30 induced Th17 polarization by increasing the production of IL‐6 and TGF‐β. In vivo, Th17 differentiation was induced by the production of key pro‐inflammatory cytokines, including IL‐6and TGF‐β, from DCs of NP30‐immunized mice. These results indicate that NP30 promotes Th17 polarization through DC activation, preventing serious schistosomiasis.
Task Variety in Professional Service Work: When It Helps and When It Hurts
Authors: Avgerinos Emmanouil , Gokpinar Bilal 
Published: March 2018

In a wide range of professional service firms, individuals perform a variety of tasks which are highly cognitive and knowledge intensive yet repetitive in nature, providing significant opportunities for learning. In addition, individuals in such environments tend to enjoy considerable discretion in managing when and how they perform their tasks. In light of these observations, we investigate task allocation and timing strategies that may enhance or inhibit learning and productivity for professional service workers. Specifically, we focus on the role of task variety. We use a detailed dataset of 3273 coronary artery bypass surgeries in a private European hospital over 7 years to examine the effect of concurrent and non‐concurrent exposure to task variety on learning and productivity on a focal task. We find that while concurrent exposure to variety has a positive impact on focal productivity, non‐concurrent exposure to variety has a negative impact on it. Our results also suggest that short‐term exposure to variety amplifies these relationships.
Guidance of spatial attention during associative learning: Contributions of predictability and intention to learn
Authors: Do Carmo Blanco Noelia , Allen John J. B. 
Published: March 2018

AbstractExpectations of an event can facilitate its neural processing. One of the ways we build expectations is through associative learning. Interestingly, the learning of contingencies between events can also occur without intention. Here, we study feature‐based attention during associative learning, by asking how a learned association between a cue and a target outcome impacts the attention allocated to this outcome. Moreover, we investigate attention in learning depending on the intention to learn the association. We used an associative learning paradigm where we manipulated outcome predictability and intention to learn an association within streams of cue‐target outcome visual stimuli, while stimulus characteristics and probability were held constant. In order to measure the event‐related component N2pc, widely recognized to reflect allocation of spatial attention, every outcome was embedded among distractors. Importantly, the location of the target outcome could not be anticipated. We found that predictable target outcomes showed an increased spatial attention as indexed by a greater N2pc component. A later component, the P300, was sensitive to the intention to learn the association between the cue and the target outcome. The current study confirms the remarkable ability of the brain to extract and update predictive information, in accordance with a predictive‐coding model of brain function. Associative learning can guide a visual search and shape covert attentional selection in our rich environments.
Detecting violation in abstract pitch patterns with mismatch negativity
Authors: Xiao Xue‐Zhen , Wong Hoi Ki , Wang Yang , Zhao Kunyang , Zeng Ginger Qinghong , Yip Long‐Yin , Wong Geoffrey Chun‐Sung , Tse Chun‐Yu 
Published: March 2018

AbstractThe human brain automatically extracts regularities embedded in environmental auditory events. This study investigated the extraction of abstract patterns by measuring mismatch negativity (MMN). Participants watched a silent subtitled movie and ignored a sequence of auditory events comprising frequent standards and rare deviants presented in the background. Tone triplets with varying pitch (first‐order property) served as the auditory events. The pitch intervals (interval 1 and interval 2) between the tones in a triplet and the ratio of interval 1 and 2 were considered second‐ and third‐order properties, respectively. Both second‐ and third‐order properties of the standards were kept constant in the mixed patterns block, while only the third‐order property was kept constant in the ratio pattern block. Four sets of tone triplets violating the interval and ratio patterns with different deviance levels were presented as deviants in both blocks, and subtracted with physically identical stimuli in a control block to isolate the MMNs. Interval and ratio pattern deviants elicited MMNs in the mixed patterns block while only ratio pattern deviants elicited MMNs in the ratio pattern block. Larger MMNs were elicited by large deviants as compared to small deviants. These results suggest that the change detection system is sensitive to the violation of both second‐ and third‐order abstract patterns. In addition to regularities in the abstract properties of auditory events, regularities in the relationships between abstract properties can also be extracted. This ability plays an important role in music and language perception.
Public Pensions and Collective Bargaining Rights: Evidence from State and Local Governments
Authors: Hoang Trang , Goodman Doug 
Published: March 2018

AbstractAn aging workforce and increasing retirement benefits are ongoing problems for states and municipalities. Unions are often blamed for governments offering too generous pension benefits. This contributes to budgetary pressures in some state and municipal governments. This article analyzes the impact of collective bargaining on pension benefit generosity under different economic conditions. The study finds that the impact of collective bargaining on pension benefits is not consistent over time or across pension plans. Collective bargaining has a positive effect on pension benefits under worsening economic conditions. Additionally, unions indirectly influence pension benefit generosity through campaign donations and unionization intensity. The findings suggest mixed impacts of collective bargaining on different groups of public employees regarding pension contributions. The article concludes with implications for the role of unions in public financial performance and strategic human resource management during fiscal austerity.
Multiple breath washout: A new and promising lung function test for patients with idiopathic pulmonary fibrosis
Authors: Nyilas Sylvia , Schreder Theresa , Singer Florian , Poellinger Alexander , Geiser Thomas Kurt , Latzin Philipp , Funke Manuela 
Published: March 2018

AbstractBackground and objectiveIdiopathic pulmonary fibrosis (IPF) is a devastating progressive lung disease affecting the parenchyma. Nitrogen multiple‐breath washout (N2‐MBW) is a lung function test that measures ventilation inhomogeneity, a biomarker of small airway disease. We assessed clinical properties of N2‐MBW in IPF.MethodsIn this prospective cohort pilot study, 25 IPF patients and 25 healthy controls were assessed at baseline and 10 patients at median 6.2 months later. Outcomes included the lung clearance index (LCI) from N2‐MBW, forced vital capacity (FVC) from spirometry, diffusion capacity of the lungs for carbon monoxide (DLCO), bronchiectasis score from computed tomography scans, the Gender–Age–Physiology (GAP score for IPF) stage and death or lung transplantation (LTx). Study end points were feasibility, repeatability, discriminative capacity and correlation with disease severity and structural lung damage.ResultsAll patients were able to perform N2‐MBW. LCI was repeatable and reproducible. Median (interquartile range (IQR)) LCI in IPF was 11.6 (10.1–13.8) in IPF versus 7.3 (6.9–8.4) in controls (P < 0.0001). LCI correlated with DLCO corrected for haemoglobin (corrDLCO; r = −0.49, P = 0.016), bronchiectasis score (r = 0.45, P = 0.024) and the GAP stage (r = 0.59, P = 0.002), but not with FVC. FVC was not related to bronchiectasis. During follow‐up, six patients died and one received LTx. LCI correlated with the latter compound outcome: hazard ratio (95% CI) was 2.43 (1.26; 4.69) per one LCI SD from the patient population.ConclusionN2‐MBW is a feasible, reliable and valid lung function test in IPF. LCI correlates with diffusion impairment, structural airway damage and clinical disease severity. LCI is a promising surveillance tool in IPF that may predict mortality.
Marginal Logistic Regression for Spatially Clustered Binary Data
Authors: Cattelan Manuela , Varin Cristiano 
Published: March 2018

SummaryClustered data are often analysed under the assumption that observations from distinct clusters are independent. The assumption may not be correct when the clusters are associated with different locations within a study region, as, for example, in epidemiological studies involving subjects nested within larger units such as hospitals, districts or villages. In such cases, correct inferential conclusions critically depend on the amount of spatial dependence between locations. We develop a modification of the method of generalized estimating equations to detect and account for spatial dependence between clusters in logistic regression for binary data. The approach proposed is based on parametric modelling of the lorelogram as a function of the distance between clusters. Model parameters are estimated by the hybrid pairwise likelihood method that combines optimal estimating equations for the regression parameters and pairwise likelihood for the lorelogram parameters. The methodology is illustrated with an analysis of prevalence disease survey data.
Estimating Material Properties Under Extreme Conditions by Using Bayesian Model Calibration with Functional Outputs
Authors: Brown J. L. , Hund L. B. 
Published: March 2018

SummaryDynamic material properties experiments provide access to the most extreme temperatures and pressures attainable in a laboratory setting; the data from these experiments are often used to improve our understanding of material models at these extreme conditions. We apply Bayesian model calibration to dynamic material property applications where the experimental output is a function: velocity over time. This framework can accommodate more uncertainties and facilitate analysis of new types of experiments relative to techniques traditionally used to analyse dynamic material experiments. However, implementation of Bayesian model calibration requires more sophisticated statistical techniques, because of the functional nature of the output as well as parameter and model discrepancy identifiability. We propose a novel Bayesian model calibration process to simplify and improve the estimation of the material property calibration parameters. Specifically, we propose scaling the likelihood function by an effective sample size rather than modelling the auto-correlation function to accommodate the functional output. Additionally, we propose sensitivity analyses by using the notion of 'modularization' to assess the effect of experiment-specific nuisance input parameters on estimates of the physical parameters. The Bayesian model calibration framework proposed is applied to dynamic compression of tantalum to extreme pressures, and we conclude that the procedure results in simple, fast and valid inferences on the material properties for tantalum.
The Role of Secondary Outcomes in Multivariate Meta-Analysis
Authors: Copas John B. , Jackson Dan , White Ian R. , Riley Richard D. 
Published: March 2018

SummaryUnivariate meta-analysis concerns a single outcome of interest measured across a number of independent studies. However, many research studies will have also measured secondary outcomes. Multivariate meta-analysis allows us to take these secondary outcomes into account and can also include studies where the primary outcome is missing. We define the efficiency E as the variance of the overall estimate from a multivariate meta-analysis relative to the variance of the overall estimate from a univariate meta-analysis. The extra information gained from a multivariate meta-analysis of n studies is then similar to the extra information gained if a univariate meta-analysis of the primary effect had a further n(1−E)/E studies. The variance contribution of a study's secondary outcomes (its borrowing of strength) can be thought of as a contrast between the variance matrix of the outcomes in that study and the set of variance matrices of all the studies in the meta-analysis. In the bivariate case this is given a simple graphical interpretation as the borrowing-of-strength plot. We discuss how these findings can also be used in the context of random-effects meta-analysis. Our discussion is motivated by a published meta-analysis of 10 antihypertension clinical trials.
Assessment of palliative care needs of patients/families living with cancer in a developing country
Authors: Ndiok Akon , Ncama Busisiwe 
Published: March 2018

PurposeThe study seeks to assess the care needs of oncology in‐patients and clinic attendees or families in two tertiary health institutions.MethodsThis was a descriptive study which utilised a quantitative survey questionnaire of all cancer patients diagnosed between January 2014 and September 2016 (n = 547) with the return rate (n = 455) representing 82%. The questionnaire explored assessment of palliative care need. These instruments were used, because patients with cancer and their families are reluctant to talk about the disease. Using a questionnaire was therefore the best means of obtaining their full participation. The data were analysed using descriptive statistics to identify the highest need of patients with cancer patients. The study was approved by the two participating hospitals and the Human and Social Sciences Research Ethics of University of KwaZulu‐Natal.FindingsThe study found that most common needs of patients were information on possibilities of treatment and side effects (92.8%), diagnosis (91.6%), testing (91.1%) and physical symptoms (90.9%). There were also other needs, such as psychological, spiritual and financial needs, related to factors causing distress to patients and their families following diagnosis of cancer.ConclusionsThis article focused on needs as expressed by patients and families and offers a useful guide to develop a model for integration of palliative care activities. The findings reveal that patients who are undergoing follow‐up care and cancer treatment or investigation are clearly concerned about receiving information on a range of cancer issues. We therefore conclude that patients are able to deal with the disease more effectively when hospitals set up a palliative care team or unit to carry out proper assessment of patients living with cancer.
Should we look beyond Kt/V urea in assessing dialysis adequacy?
Authors: Jones Clare B. , Bargman Joanne M. 
Published: March 2018

AbstractSince the advent of maintenance dialysis therapy, our interpretation of what adequate dialysis really is has broadened and become more controversial. This is not only due to our changing and aging dialysis population but also to our evolving knowledge base. As nephrologists, we strive to achieve both quality and (often) quantity of life for our patients and we feel reassured when we have a quantifiable marker to show for our efforts. However, we suggest that adequate dialysis reaches far beyond the realms of attaining a particular biochemical result. Dialysis adequacy should encompass a more comprehensive assessment of patient well‐being. This metric could comprise quality of life and patient‐specified goals, sufficient small solute and middle molecule clearance, optimal blood pressure control, and effective bone‐mineral balance, all in the context of minimizing mortality and morbidity, and a livable dialysis regimen for the patient.
Tectonically controlled initiation of contemporaneous deep‐water channel systems along a Late Cretaceous continental margin, western British Columbia, Canada
Authors: Englert Rebecca G. , Hubbard Stephen M. , Coutts Daniel S. , Matthews William A. 
Published: March 2018

AbstractSubmarine channel‐systems are globally prevalent on continental margins and their deposits record the transfer of significant volumes of sediment from continental catchments to deep‐water environments. These deposits contain signals of past events that can provide critical insight into the geological history of an area, including the long‐term (>1 Ma) controls on sedimentation. Well‐exposed outcrops of the Late Cretaceous Nanaimo Group, British Columbia, Canada, provide an opportunity to investigate long‐term sediment‐routing in a tectonically active setting. This study combines detrital zircon geochronology with stratigraphic analysis to establish a robust, basin‐wide palaeogeographic framework that constrains the timing and distribution of coarse‐grained sediment transport and deposition in the Nanaimo forearc basin. Three south‐west trending submarine conduits are documented along a 135 km long strike‐oriented transect, parallel to the north‐west/south‐east trending basin. Composite conduit deposits are 350 to 700 m thick, 4 to 16 km wide, and record substantial delivery of coarse‐grained detritus (up to boulder‐sized clasts) within submarine channel‐levée systems. Maximum depositional ages derived from detrital zircon datasets constrain contemporaneous sediment transfer and deposition at each conduit location, which spanned between 73·5 ± 1·3 Ma to 69·1 ± 1·1 Ma around the Campanian–Maastrichtian boundary. Submarine conduits are spaced at 40 km and 70 km, and were likely connected to fluvial drainage systems sourced in uplifted catchments. Widespread, coarse‐grained deposits suggest that surface uplift associated with concurrent regional events (such as deformation and/or magma emplacement) along the North American margin may have promoted sediment delivery to the deep‐water basin. Comparisons to modern and ancient analogues support palaeogeographic interpretations, as well as the interpretation that pervasive coarse‐grained deep‐water sediment delivery was linked to tectonic activity. The integrated stratigraphic–geochronological approach used provides unique insight into the influence of regional tectonics on continental margin physiography and the nature of deep‐water sediment dispersal.
Understanding the Pathways from Depression to Suicidal Risk from the Perspective of the Interpersonal–Psychological Theory of Suicide
Authors: Kang Nan , You Jianing , Huang Jiyi , Ren Yaxuan , Lin Min‐pei , Xu Sian 
Published: March 2018

Suicide is a major public health concern, especially in adolescence. Identifying risk factors for suicide is important to effectively prevent such behavior. Depression is one of the most widely examined risk factors for suicidal risk. How depression and suicidal risk are related, however, is still not clear. This study tested a model with three key constructs of the interpersonal–psychological theory of suicidal behavior (IPTS)—perceived burdensomeness, thwarted belongingness, and nonsuicidal self‐injury (NSSI)—as mediators in the relationship between depression and suicidal risk among Chinese adolescents. Chinese high school students (N = 1,074; 54.2% male; Mage = 13.87 years, SD = 1.48) completed questionnaires assessing all study variables. Results suggested that perceived burdensomeness and NSSI partially mediated the relationship between depression and suicidal risk. Findings of this study emphasize the importance of the IPTS framework in understanding the possible mechanisms underlying the relationship between depression and suicidal risk, and suggest a possible avenue for suicide interventions.
The effect of Nordic hamstring exercise training volume on biceps femoris long head architectural adaptation
Authors: Presland J. D. , Timmins R. G. , Bourne M. N. , Williams M. D. , Opar D. A. 
Published: March 2018

The aim of this study was to determine the time course of architectural adaptations in the biceps femoris long head (BFLH) following high or low volume eccentric training. Twenty recreationally active males completed a two week standardized period of eccentric Nordic hamstring exercise (NHE) training, followed by four weeks of high (n = 10) or low volume (n = 10) training. Eccentric strength was assessed pre‐ and post intervention and following detraining. Architecture was assessed weekly during training and after two and four weeks of detraining. After six weeks of training, BFLH fascicles increased significantly in the high (23% ± 7%, P < .001, d = 2.87) and low volume (24% ± 4%, P < .001, d = 3.46) groups, but reversed following two weeks of detraining (high volume: −17% ± 5%, P < .001, d = −2.04; low volume: −15% ± 3%, P < .001, d = −2.56) after completing the intervention. Both groups increased eccentric strength after six weeks of training (high volume: 28% ± 20%, P = .009, d = 1.55; low volume: 34% ± 14%, P < .001, d = 2.09) and saw no change in strength following a four week period of detraining (high volume: −7% ± 7%, P = .97, d = −0.31; low volume: −2% ± 5%, P = .99, d = −0.20). Both low and high volume NHE training stimulate increases in BFLH fascicle length and eccentric knee flexor strength. Architectural adaptations reverted to baseline levels within two weeks after ceasing training, but eccentric strength was maintained for at least four weeks. These observations provide novel insight into the effects of training volume and detraining on BFLH architecture and may provide guidance for the implementation of NHE programs.