bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual Mobility Cups: Effect on Risk of Revision of Primary Total Hip Arthroplasty Due to Osteoarthritis
Authors: Kreipke Rasmus , Rogmark Cecilia , Pedersen Alma B. , Kärrholm Johan , Hallan Geir , Havelin Leif Ivar , Mäkelä Keijo , Overgaard Søren 
Published: January 2019

Background:
The dual mobility acetabular cup (DMC) was designed to reduce prosthetic instability and has gained popularity for both primary and revision total hip arthroplasty (THA). We compared the risk of revision of primary THA for primary osteoarthritis between patients treated with a DMC and those who received a metal-on-polyethylene (MoP) or ceramic-on-polyethylene (CoP) bearing.

Methods:
A search of the Nordic Arthroplasty Register Association (NARA) database identified THAs performed with a DMC during 1995 to 2013. With use of propensity score matching, 2,277 of these patients were matched (1:1), with regard to sex, age, component fixation, and year of surgery, with patients with an MoP or CoP bearing. We estimated the cumulative incidence of revision taking death as a competing risk into consideration and performed competing risk regression with revision or death as end points.

Results:
There was no difference in the overall risk of revision between the DMC group and the propensity-score-matched MoP/CoP group (adjusted hazard ratio [HR] = 1.18; 95% confidence interval [95% CI] = 0.87 to 1.62). Patients with a DMC bearing had a lower risk of revision due to dislocation (adjusted HR = 0.09; 95% CI = 0.03 to 0.29) but a higher risk of revision caused by infection (adjusted HR = 3.20; 95% CI = 1.49 to 6.85).

Conclusions:
There was no difference in overall risk of revision between the DMC and MoP/CoP groups. The DMCs protected against revision due to dislocation but THAs performed with this bearing were more commonly revised because of infection. There may have been a selection bias toward placing DMC implants in patients with greater frailty as the mortality rates were higher in the DMC group than in the age and sex-matched MoP/CoP group.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Clinical Application of Teriparatide in Fracture Prevention
Authors: Chen Yuehong , Liu Ronghan , Hettinghouse Aubryanna , Wang Shuya , Liu Gang , Liu Chuan-ju 
Published: January 2019

Background:
Teriparatide, a 1-34 fragment of parathyroid hormone (PTH) that maintains most of the biological activities of PTH, has been employed since 2002 as an anabolic agent for osteoporotic individuals who are at high risk of fracture. The purpose of the present review is to provide a systematic summary and timely update on treatment with teriparatide for fracture prevention.

Methods:
Electronic databases, including OVID MEDLINE, OVID Embase, and the Cochrane Library, were searched on February 9, 2018, to identify published systematic reviews and meta-analyses addressing treatment with teriparatide for fracture prevention, and A Measurement Tool to Assess Systematic Reviews 2 (AMSTAR 2) was used to assess the quality of included studies.

Results:
Seventeen studies were included. Of the 17 eligible studies, 3 were rated as high quality, 3 were rated as moderate quality, 6 were rated as low quality, and 5 were rated as critically low quality. Teriparatide reduced vertebral and overall nonvertebral fractures in osteoporotic patients regardless of the existence of precipitating conditions, including postmenopausal status, glucocorticoid treatment, and chronic kidney disease, as compared with placebo, but not the site-specific nonvertebral fractures of the wrist and hip. Teriparatide did not more effectively reduce fracture risks when compared with other medications, such as bisphosphonates, selective estrogen receptor modulators, RANKL (receptor activator of nuclear factor kappa-beta ligand) inhibitor, or strontium ranelate.

Conclusions:
Teriparatide was safe and was not associated with an increased rate of adverse events when compared with other drugs. Teriparatide was effective for the prevention of vertebral and overall nonvertebral fractures in osteoporotic patients but not for the prevention of site-specific nonvertebral fractures at the wrist and hip.

Level of Evidence:
Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
Informative Supraglottic Airway versus Endotracheal Tube During Interventional Pulmonary Procedures – A Retrospective Study
Authors: Behrens Kyle M , Galgon Richard E 
Published: January 2019

Abstract
Background: As the field of interventional pulmonology (IP) expands, anesthesia services are increasingly being utilized when complex procedures of longer duration are performed on sicker patients with high risk co-morbidities and lung pathology. Yet, evidence on the optimal anesthetic management for these patients remains lacking. Our aim was to characterize the airway management and, secondarily anesthetic maintenance patterns used for IP procedures at our institution.
Methods: From 2894 identified encounters, charts of 783 patients undergoing an IP procedure with general anesthesia over a 5-year period, employing an endotracheal tube (ETT) or a supraglottic airway (SGA) for airway maintenance, were identified and reviewed after exclusions. Patients posted for a concurrent thoracic surgical procedure and those already intubated at presentation were excluded. Baseline patient demographics, procedure, proceduralist type, anesthesia maintenance modality, neuromuscular blocking drug (NMBD) use, and airway management characteristics were extracted and analyzed.
Results: Inhaled general anesthesia with an ETT for airway maintenance was most commonly employed; however, SGAs were used in one-third of patients with a very low conversion rate (0.4%), and their use was associated with a significant reduction in NMBD use.
Conclusions: In this large series of patients receiving general anesthesia for IP procedures, inhaled anesthetic agents and ETTs were favored. However, in appropriately selected patients, SGA use was effective for airway maintenance and allowed for a reduction in NMBD use, which may have implications in this patient population who may have an increased risk for pulmonary complications and warrants further investigation.
Keywords: Supraglottic airway, endotracheal tube, airway maintenance, interventional pulmonology, neuromuscular blocking
Difficult Airway caused by a Subglottic Tumor: A Case Report
Authors: Ye Xuefei , Jiang Xiaofeng , Lan Haiyan , Yang Yun , Lian Qingquan 
Published: January 2019

Abstract
Background: Securing the airway is a core skill for an anesthesiologist, the gold standard of which is tracheal intubation. Patient with subglottic tumor is a situation of difficult airways and could be a challenge for anesthesiologists. The “cannot ventilate, cannot intubate” during anesthesia induction can be lethal. So we always prepared awake approach for diagnosed difficult airway, but awake fiberoptic intubation may be also failed.
Case presentation: In this case report we present a 55 years old female patient was scheduled for laryngeal tumor resection, and was planned awake intubation guided by fiber bronchoscope. After awake intubation attempt failed, emergency tracheostomy was successfully completed by ENT surgeon. After securing airway, general anesthesia was performed and the operation proceeded with laryngeal tumor resection.
Conclusions: It is important that ENT surgeon must be asked to remain standby for possible need of emergency tracheostomy to prevent awake fiberoptic intubation failure. Ultrasound or computed tomography scan examination of the trachea may be useful to provide guidance for anesthesiologists to choose the appropriate endotracheal tube IDs or tracheostomy directly by measuringthe degree of airway stenosis.
Keywords: Subglottic Tumor; difficult airway; ENT; anesthesia
The Lodge Maribaya Sebagai Salah Satu Pilihan Destinasi Ekowisata Kabupaten Bandung Barat
Authors: Machdalena Susi , Dewi Anggraeni Purnama , Soemantri Ypsi Soeria 
Published: January 2019

One of the eco-tourism destination in West Bandung Regency is ‘ The Lodge Maribaya’. It is a nature-based place, surroundings by the hills and pine-trees forest with full of the fresh-air. Besides the beautiful scenery, there are some children playground equipments, such as swings, and slides, there are also some play-equipments for adults, such as Sky–bike or Zip-bike, the equipment for riding the bike on a rope-track up in the sky. Then, a Sky wing is a swing in the edge of a cliff for selfie. The theory of Damanik and Weber (2006) is classified the tourism destination like this is a development of the natural resource to magically attraction , beautiful view, and comfortable fresh-air.
NEW PAGE IN U.S.-ISRAEL RELATIONS. D. TRUMP: EXPECTATIONS, HOPES AND FEARS
Authors: KARASOVA T. A. 
Published: January 2019

The U.S.-Israel relationship has never existed in a vacuum; it has always been part of a broader regional strategy. Israel hoped the 45th president of the United States has ostensibly ended an eight- year deterioration of the U.S.-Israel relationship. He committed himself to pro-Israeli positions, which was welcomed in Jerusalem. However, Trump’s precise policy vis-à-vis Israel is likewise difficult to define. He made problematic statements regarding the issue of foreign aid to US allies, and declared that he would be neutral regarding the Israeli-Palestinian conflict. Israel is still facing more questions than answers. Some are rooted in the uncertainty relating to the new US administration and the implications of that change for Israel’s strategic environment, but many are linked to the Israeli penchant for avoiding decisions that it must make for itself. In the international arena, it is important to rebuild Israel’s status by relying not only on the Trump administration. Some Israeli politicians believe that Trump’s unquestioning support means trouble for Israel. The Trumportunity is by no means a guarantee. The opportunity here is just that, an opportunity.
Upaya Pengolahan Limbah Kotoran Babi Menggunakan Komposter Rumah Tangga
Authors: Sari Widya , Budiarsa Suyasa I Wayan , Sila Dharma I.G.B 
Published: January 2019

ABSTRACT
The production of pig manure waste potentially pollutes the soil, water and air. One of the most effective processing a waste treatments is through composting. The composting process takes a long time if not assisted by the activator as decomposers of organic materials in order to accelerate the composting process. Activators such as local microorganism (MOL) contain macro nutrients, micro and active microorganism that potentially decomposed organic materials, growth stimulants and pest/disease control agents such as to help speed up the composting process. This study aims to determine the C/N ratio of optimal raw materials for composting of pig manure and vegetable waste, determining the effect of adding local microorganism (MOL) to the length of time of composting and determining the effectiveness of business from composting of pig manure and vegetable waste based on the calculation of B/C ratio.
This research uses quantitative approach with experiment method. The first stage is the preparation of the raw material which is divided into three groups : composition 1 with 75% (pig manure) and 25% (vegetable waste), composition 2 with 50% (pig manure) and 50% (vegetable waste) and then composition 3 with 25% (pig manure) and 75% (vegetable waste). Furthermore, the best raw material composition was treated with variations of MOL addition of A (100 ml), B (300 ml), C (500 ml) and D (without MOL).
The results showed that the composition of the best raw material mixture was a mixture composition of 25% (pig manure) and 75% (vegetable waste) with a C/N ratio of 38.95. The effect of MOL addition indicates that the greater MOL volume the faster to composting process. The quality compost with addition of MOL has C/N ratio levels is (16,30), N-total (1,65%), P tersedia (8043,02 ppm), K tersedia (8857,40 ppm), Fe (1,87%), Mn (0,09%) Zn (480 ppm) in which that value meets the SNI 19-7030-2004. Based on analysis of B/C ratio obtained result of 1.04 where the value is approaching criteria B/C ratio more than 1.00 which means compost business feasible to be developed.

Keywords : Pig manure, MOL, time of composting, composter, B/C ratio
PENGOLAHAN LIMBAH CAIR INDUSTRI BATIK SEBAGAI SALAH SATU PERCONTOHAN IPAL BATIK DI YOGYAKARTA
Authors: Indrayani Lilin 
Published: January 2019

Abstrak
Dewan Kerajinan Dunia (Word Craft Council) telah menganugrahkan sebuah predikat pada Yogyakarta sebagai Kota Batik Dunia. Peningkatan industri batik di Yogyakarta disamping memberikan pengaruh positif terhadap peningkatan ekonomi dan kesejahteraan masyarakat juga memberikan dampak negatif terhadap lingkungan. Salah satu masalah lingkungan tersebut adalah munculnya limbah cair industri batik dalam kuantitas yang cukup besar. Oleh karena diperlukan suatu model percontohan IPAL agar industri batik di Yogyakarta sehingga pelaku industri batik mendapatkan suatu rujukan teknis sistem pengolahan limbah batik. Dalam penelitian ini diperkenalkan sistem pengolahan limbah cair batik dengan beberapa perlakuan secara fisika, kimia dan biologi. Sehingga diharapkan limbah cair industri batik yang diolah melalui percontohan IPAL ini dapat memenuhi baku mutu yang telah ditetapkan sesuai dengan SK Gubernur DIY No 7 tahun 2016 tentang Baku Mutu Air Limbah Bagi Industri Batik. Sehingga limbah cair industri batik dapat dinyatakan aman apabila dibuang ke lingkungan.
PENGARUH PUPUK CAIR URINE SAPI TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN JAGUNG MANIS ( Zea mays L.)
Authors: Pangaribuan Darwin Habinsaran , Sarno . , Kurniawan Muhammad Chandra 
Published: January 2019

Tujuan dari penelitian ini adalah untuk mengetahui apakah pupuk cair urine sapi dapat mengurangi penggunaan Urea dalam upaya untuk meningkatkan pertumbuhan dan produksi jagung manis. Penelitian ini dilakukan di Bandar Lampung. Mulai April sampai Juli 2015. Penelitin menggunakan rancangan acak kelompok dengan lima perlakuan, yaitu (P0) kontrol, (P1) pupuk Urea 270 gram, (P2) urine sapi 7 ml/l (7.000 ppm) pada 2, 4, 6, dan 8 MST, (P3) pupuk Urea 135 gram dan urine sapi 7 ml/l (7.000 ppm) pada 3 dan 5 MST dan (P4) pupuk Urea 135 gram dan urine sapi 7 ml/l (7.000 ppm) pada 2, 4, 6, dan 8 MST. Hasil penelitian menunjukkan bahwa pupuk cair urine sapi memberikan pengaruh nyata terhadap variabel pertumbuhan dan produksi tanaman jagung manis. Perlakuan P2 pada 2, 4, 6 dan 8 MST direkomendasikan sebagai pupuk alternatif Urea.
Persepsi Penumpang Terhadap Pelayanan Angkutan Terintegrasi Busway (Aptb) (Studi Kasus: Rute Rawamangun-Bogor)
Authors: Fitriani Evy 
Published: January 2019

Penolakan salah satu organisasi kemasyarakatan (ormas) yang menganggap kehadiran APTB akan mengancam kelangsungan angkot dan persepsi masyarakat khususnya warga kota Bogor terhadap keberadaan APTB sebagai salah satu alternatif transportasi dengan memperhatikan faktor-faktor kenyamanan, keamanan dan keselamatan tetapi tanpa mengesampingkan nasib para operator angkot melatar belakangi disusunnya kajian ini. Tujuan kajian adalah menemukenali factor-faktor yang mempengaruhi dan juga memahami penilaian penumpang terhadap pelayanan APTB sehingga dapat dirumuskan langkah-langkah terhadap perbaikan dan peningkatan mutu pelayanannya. Berdasarkan hasil pengolahan data dengan analisis faktor di dapatkan 10 faktor utama yang harus dijadikan prioritas bagi pengembangan pelayanan APTB ke depan. Kata kunci : penumpang, pelayanan, APTB
Evaluasi Pelayanan Angkutan Danau Sentani
Authors: Mulyahadi Mulyahadi 
Published: January 2019

Danau Sentani adalah danau yang berada di Kabupaten Jayapura, yang memiliki luas sekitar 9.360 hektar dan terdapat 24 kampung tersebar dipesisir dan pulau-pulau kecil yang ada ditengah danau. Aktifitas masyarakat disekitar danau sehari-hari selalu tergantung kepada angkutan danau yang menghubungkan desa/kampung dengan desa/kampung lainnya, tetapi kurang ditunjang fasilitas palabuhan danau yang memadai. Untuk itu perlu adanya evaluasi sejauhmana kondisi pelayanan angkutan danau sentani dilihat dari jenis sarana dan tingkat kepuasan pelanggan. Hasil wawancara terhadap penumpang dan nakhoda kapal dengan mengggunakan metode analisis statistik danImportance-Performance, maka didapatkan proporsi penumpang 53% perempuan, 40% usia 21-30 thn, 91% frekwensi lebih dari 5 kali/minggu, 37% masyarakat dari Desa Yahim dengan tujuan Kp. Putrani (28%) dan dalam pelayanannya dari hasil opini penumpang perlu ditingkatkan adalah perbaikan fasilitas Pelabuhan Danau Yahim. Kata kunci: evaluasi, pelayanan, angkutan danau
Pengaruh H2O pH 5,2 dan TE Buffer pH 7,8, Untuk Perbaikan Efisiensi Reaksi qPCR Skoring HER-2 Kanker Payudara
Authors: Mirnawati Farida , Abinawanto Abinawanto , Bowolaksono Anom , Wulandari Dwi , Budiarto Bugi Ratno , Warisman M. Ali , Widyowati Henny , Azamris Azamris , Rustamadji Primariadewi , Desriani Desriani 
Published: January 2019

Abstrak. Validitas reaksi qPCR untuk aplikasi teknologi diagnostik ataupun deteksi sangat penting. Reaksi qPCR yang valid, akan memberikan hasil dengan tingkat kepercayaan yang tinggi. Untuk mengukur validitas reaksi dapat dilakukan dengan mengukur nilai Koefisien korelasi (R2), Efisiensi (E), dan Coefficient of variability (CV) yang terbentuk. Her-2 merupakan protein proto-onkogen sebagi biomarker prognosis dan factor prediktif pengobatan terhadap trastuzumab. Penentuan skoring status HER-2 dapat dilakukan menggunakan teknik Immunohistochemistry (IHC), Fluorosence In Situ Hibriditation (FISH) dan qPCR. Dari ketiga teknik diatas, pendekatan menggunakan qPCR merupakan pendekatan yang dapat dikuantifikasi. Untuk mengkuantifikasi status skoring HER-2 dibutuhkan pengukuran amplifikasi HER-2 dan gen kalibrator. Gen WHN merupakan salah satu gen yang dapat digunakan sebagai kalibrator skoring HER-2. Efisiensi qPCR dilaporkan dipengaruhi oleh banyak faktor, diantaranya adalah pH. pH diketahui berpengaruh terhadap kerja dari polymerase dan integritas DNA. Pada penelitian ini akan dibandingkan dua pelarut berbeda, H2O pH 5,2 dan Buffer TE pH 7,8 terhadap efisiensi reaksi qPCR skoring HER-2. Preparasi pGEM-T easy whn juga akan dilaporkan pada penelitian ini menggunakan teknik yang standar, yang kemudian akan digunakan sebagai bahan DNA template untuk pengenceran secara serial dengan dua kali factor pengenceran untuk mengukur nilai R2, E, dan CV yang menjadi parameter validitas reaksi qPCR. Dari hasil penelitian ini nilai Ct pGEM-T whn yang dilarutkan dengan H2O pH 5,2 memiliki nilai Ct lebih rendah dibandingkan dengan TE buffer pH 7,8, yang secara signifikan mempengaruhi efisiensi qPCR. Nilai R2 dan E reaksi qPCR untuk H2O pH 5,2 dan TE buffer pH 7,8 adalah: 0,98 dan 115%; 0,99 dan 99% untuk masing-masingnya . Selanjutnya nilai CV yang terbentuk berada dibawah 10% pada kedua pelarut tersebut. Hasil konfirmasi dengan elektroforesis gel dan analisis melt peak untuk kedua standar menunjukkan satu pita tunggal dengan ukuran yang ditargetkan (93 bp) dan peak tunggal dengan Tm ±81 oC. Berdasarkan hasil penelitian ini, TE buffer pH 7,8 merupakan pelarut ideal untuk mendapatkan efisiensi uji qPCR yang ideal untuk aplikasi penentuan skoring status HER-2 pada pasien kanker payudara berdasarkan metode qPCR. Kata kunci: kurva standar, qPCR, RNase- free water, TE buffer, koefisien korelasi (R2), efisiensi
HISTOLOGI JARINGAN MANTEL TIRAM (SAIBO) PADA BEBERAPA JENIS BIVALVIA SEBAGAI ALTERNATIF IMPLANTASI MUTIARA
Authors: Eddy La , Riandini Rezki Amalia , Moniharapon Mechiavel 
Published: January 2019

All types of bivalves have the potential to produce pearls. Pearls can be produced naturally and cultivated. In cultured pearls, pearl sac are obtained from saibo (slices of another bivalve mantle) that which come from pallial zone. This study wants know the structures of tissues saibo of several species of bivalves as an alternative pearls implantation. This study is conducted from January to March 2017. This study used 7 types of bivalves among others; Pinctada margaritifera, Saccostrea cucullata, Asaphis violascens, Polymesoda bengalensis, Pinna muricata, Volachlamys singaporina, and Tridacna crocea. The method used by staining Hematoxylin-Eosin. Thisstudy show results that every saibo has the different characteristic, but has a common characteristic of having outer epithelium mantle, inner epithelium mantle, muscle fibers, connective tissue and longitudinal muscle, so it can be recommended in pearls implantation Keywords : Saibo, Bivalvia, Implantasi Mutiara[H1] [H1]Disusun berdasarkan abjad
СОВРЕМЕННОЕ СОСТОЯНИЕ ЗЕМЕЛЬНЫХ РЕСУРСОВ КЕМЕРОВСКОЙ ОБЛАСТИ И ИХ ИСПОЛЬЗОВАНИЕ
Authors: Подурец Ольга Ивановна 
Published: January 2019

Цель работы. Охарактеризовать динамику земельных ресурсов Кемеровской области по категориям их целевого назначения. Методология проведения работы. Статистический анализ динамики соотношения площади земель основных категорий и их доли в земельном фонде проведен за 30-летний период (1985–2015 годы) на основании официальных данных Главного управления природных ресурсов, охраны окружающей среды и департамента по сельскому хозяйству администрации области. Результаты работы. С учетом развития и размещения производительных сил постепенно происходит перераспределение земельного фонда. Проведенный мониторинг современной структуры земельных ресурсов выявил существенные изменения по всем категориям их целевого назначения. Отмечено значительное увеличение площади под населенные пункты, особо охраняемые территории и лесного фонда. Наибольшее сокращение характерно для земель сельскохозяйственного назначения, площадь которых за 30 лет уменьшилась на 1232,1 тысячи гектар, а доля площади в структуре земельного фонда снизилась с 40,7 % до 27,8 %. Основными причинами уменьшения площади являются: перевод земель сельскохозяйственного назначения в земли промышленности, транспорта, связи и другого специального назначения; проведение работ по разграничению государственной собственности; частичное зарастание сельскохозяйственных полей. Негативным результатом таких изменений является процесс отторжения из хозяйственного оборота высокопродуктивных сельскохозяйственных земель, представленных черноземными и серыми лесными почвами, и образование на их месте нарушенных производственной деятельностью техногенных структур. Область применения результатов. Изучение динамики земельных ресурсов на фоне высокой индустриализации региона, расширения границ промышленного производства и значительного увеличения объемов добычи полезных ископаемых необходимо для решения вопросов по их рациональному использованию и актуализации природоохранной деятельности. Выводы. Деградация почв сельскохозяйственных угодий является важнейшей социально-экономической проблемой области. Для оптимизации экологической обстановки в регионе необходимо увеличить площадь охраняемых территорий и активизировать рекультивационную деятельность.