bluuebunny/crossref_metadata_2025_split huggingface dataset:
Shedding light on the migratory patterns of the Amazonian goliath catfish, Brachyplatystoma platynemum, using otolith 87Sr/86Sr analyses
Authors: Hauser Marília , Doria Carolina R.C. , Santos Roberto V. , García‐Vasquez Aurea , Pouilly Marc , Pécheyran Christophe , Ponzevera Emmanuel , Torrente‐Vilara Gislene , Bérail Sylvain , Panfili Jacques , Darnaude Audrey , Renno Jean‐François , García‐Dávila Carmen , Nuñez Jesus , Ferraton Franck , Vargas Gladys , Duponchelle Fabrice 
Published: February 2019

Abstract

In the Amazon, migratory catfishes of the genus Brachyplatystoma are apex predators that are important for fisheries and conservation. The life cycle of Brachyplatystoma platynemum Boulenger, 1898 is poorly known, although it has been hypothesized to be very similar to that of Brachyplatystoma rousseauxii Castelnau, 1855, which uses the entire length of the Amazon basin to complete its life cycle (from the Andes to the estuary). This study provides the first data on the migratory patterns of B. platynemum at the individual level using otolith microchemistry.
In total, 94 individuals were sampled close to major breeding areas in the Amazon basin (78 fish from the middle and upper Madeira River and 14 fish from the upper Amazon), and their lifetime movements were assessed by measuring variations in 87Sr/86Sr along transverse sections of their otoliths (ear stones), using laser ablation multi‐collector mass spectrometry (LA‐MC‐ICP‐MS).
The migrations of B. platynemum are not as extensive as those of B. rousseauxii, and do not involve natal homing. Furthermore, the estuary is not a nursery area, at least for fish hatched in the Madeira. Nevertheless, B. platynemum migrates several thousand kilometres within the Amazon basin, with transboundary displacements between at least Bolivia, Brazil, and Peru.
Current and planned hydroelectric development in the Amazon basin will severely disrupt both migration and access to breeding grounds, ultimately affecting the recruitment and population dynamics of these apex predators.
The conservation of B. platynemum is crucial for the stability of the Amazonian aquatic food webs. This requires building effective fish passage on the two existing Madeira dams and considering alternative options to the large‐scale hydropower development in the Amazon basin.
Collagen XIII and Other ECM Components in the Assembly and Disease of the Neuromuscular Junction
Authors: Heikkinen Anne , Härönen Heli , Norman Oula , Pihlajaniemi Taina 
Published: February 2019

ABSTRACTAlongside playing structural roles, the extracellular matrix (ECM) acts as an interaction platform for cellular homeostasis, organ development, and maintenance. The necessity of the ECM is highlighted by the diverse, sometimes very serious diseases that stem from defects in its components. The neuromuscular junction (NMJ) is a large peripheral motor synapse differing from its central counterparts through the ECM included at the synaptic cleft. Such synaptic basal lamina (BL) is specialized to support NMJ establishment, differentiation, maturation, stabilization, and function and diverges in molecular composition from the extrasynaptic ECM. Mutations, toxins, and autoantibodies may compromise NMJ integrity and function, thereby leading to congenital myasthenic syndromes (CMSs), poisoning, and autoimmune diseases, respectively, and all these conditions may involve synaptic ECM molecules. With neurotransmission degraded or blocked, muscle function is impaired or even prevented. At worst, this can be fatal. The article reviews the synaptic BL composition required for assembly and function of the NMJ molecular machinery through the lens of studies primarily with mouse models but also with human patients. In‐depth focus is given to collagen XIII, a postsynaptic‐membrane‐spanning but also shed ECM protein that in recent years has been revealed to be a significant component for the NMJ. Its deficiency in humans causes CMS, and autoantibodies against it have been recognized in autoimmune myasthenia gravis. Mouse models have exposed numerous details that appear to recapitulate human NMJ phenotypes relatively faithfully and thereby can be readily used to generate information necessary for understanding and ultimately treating human diseases. Anat Rec, 2019. © 2019 Wiley Periodicals, Inc.
Bestimmung der zentrischen Nachrisszugfestigkeit von UHPFRC mithilfe gekerbter 3‐Punkt‐Biegezugversuche
Authors: Oettel Vincent , Matz Henrik , Empelmann Martin 
Published: February 2019

AbstractSowohl die zentrische Matrixzugfestigkeit als auch die zentrischen Nachrisszugfestigkeiten von faserbewehrten Betonen werden in der Regel indirekt über Biegezugversuche ermittelt. Dazu muss eine in Versuchen ermittelte Kraft‐Verformungs‐Kurve in eine Zugspannungs‐Dehnungs‐Beziehung überführt werden. Für ultrahochfesten Faserbeton (UHPFRC) gibt es in Deutschland zurzeit mangels gültiger Normen und Richtlinien kein geregeltes derartiges Umrechnungsverfahren. Zur Untersuchung des Zugspannungs‐Dehnungs‐Verhaltens von UHPFRC wurden am iBMB, Fachgebiet Massivbau der TU Braunschweig gekerbte 3‐Punkt‐Biegezugversuche nach DIN EN 14651 durchgeführt. Unter Berücksichtigung der Versuchsergebnisse und in Anlehnung an den Model Code 2010, der normal‐ und hochfesten Faserbeton regelt, wurde ein Umrechnungsverfahren für UHPFRC entwickelt. Zur Validierung des Verfahrens wurde die Finite‐Elemente‐Methode (FEM) hinzugezogen.
Einfluss der Wassersättigung auf die statische und dynamische Druckfestigkeit von Beton
Authors: Mosig Oliver , Curbach Manfred 
Published: February 2019

AbstractUntersucht wurde der Einfluss der Wassersättigung auf die statische und dynamische Druckfestigkeit von Beton. Hierzu wurden zwei verschiedene Probengeometrien mit definierten Sättigungsgraden getestet. Für die dynamischen Druckfestigkeitsversuche wurde der Split‐Hopkinson‐Bar verwendet. Es wurde festgestellt, dass die Druckfestigkeit von Beton mit steigendem Sättigungsgrad abnimmt, sowohl im statischen als auch im dynamischen Belastungsfall. Der Betrag der Abminderung der Druckfestigkeit mit steigender Sättigung ist im statischen und dynamischen Fall gleich. So kann festgehalten werden, dass der Einfluss der Wassersättigung unabhängig von der Dehn‐ und Belastungsgeschwindigkeit ist. Die trockenen Proben versagten explosionsartiger mit einer erhöhten Riss‐ und Bruchstückanzahl im Vergleich zu den wassergesättigten Probekörpern.
Polysomnographic and neuropsychological characteristics of rapid eye movement sleep behavior disorder patients
Authors: Zhang Xuan , Song Zhiyi , Ye Jingyi , Fu Ying , Wang Jinying , Su Lei , Zhu Xiaodong , Zhang Meiyun , Cheng Yan , Wu Wei , Xue Rong 
Published: February 2019

AbstractObjectivesTo compare the sleep characteristics and cognition between rapid eye movement sleep behavior disorder (RBD) patients and non‐RBD (nRBD) healthy control subjects and to determine the correlation between sleep and cognition in RBD patients.MethodsPolysomnography (PSG) was performed to confirm and exclude RBD. Fifteen iRBD patients, 12 PD with RBD patients, and 23 matched nRBD healthy control subjects were enrolled. Subjective sleep and neuropsychological evaluations were performed.ResultsNo differences were found in the subjective sleep among the three groups. Compared to the nRBD subjects, iRBD patients showed higher PLMI, the PD with RBD patients showed an increased proportion of N1 sleep, a decreased proportion of N2 and N3 sleep, and an increased periodic leg movement index. The iRBD patients performed worse on RCFT time than the nRBD subjects, the PD with RBD patients performed worse than the nRBD subjects on the following evaluations: the Mini‐Mental State Examination; auditory verbal learning test (AVLT); Rey Complex Figure Test (RCFT) time, Clock drawing test (CDT); delay memory score of RCFT; Symbol digit modalities test (SDMT); Trail Making Test (TMT); and Stroop Test B and C, all significant changes (all p < 0.05). Furthermore, in RBD patients, lower sleep efficiency was correlated with decreased SDMT scores (r = 0.694, p < 0.01), longer time on the TMT A (r = −0.589, p < 0.01), and lower city fluency test scores(r = 0.556, p < 0.01). Less total sleep time was correlated with lower RCFT scores (r = 0.392, p = 0.043), longer time on the TMT A (r = −0.417, p = 0.031), and lower city fluency test scores (r = 0.405, p = 0.036).ConclusionsPD with RBD patients suffered from abnormal sleep architecture and extensive cognition dysfunction. Decreased total sleep time and sleep efficiency may contribute to cognitive deterioration in RBD patients.
Risk of recurrence and bleeding in patients with cancer‐associated venous thromboembolism treated with rivaroxaban: A nationwide cohort study
Authors: Søgaard Mette , Nielsen Peter Brønnum , Skjøth Flemming , Kjældgaard Jette Nordstrøm , Larsen Torben Bjerregaard 
Published: February 2019

AbstractBackgroundRivaroxaban could be an attractive alternative to low molecular weight heparin for the treatment of cancer‐associated venous thromboembolism (VTE) but the safety and effectiveness remain unclear. We examined risk of recurrent VTE and major bleeding associated with rivaroxaban treatment of cancer‐associated VTE.MethodsThrough linkage of nationwide Danish registries, we identified all adults with cancer‐associated VTE initiating treatment with rivaroxaban, 2012‐2017. We estimated rates and absolute risk of the primary outcome of recurrent VTE and major bleeding; all‐cause mortality was studied as a secondary outcome.ResultsWe identified 8901 patients with cancer‐associated VTE of whom 476 (5.3%) redeemed a prescription for rivaroxaban within 30 days of VTE diagnosis (mean age 71.5 years, 41% females, 57% with pulmonary embolism). Median time from cancer diagnosis to rivaroxaban prescription was 31 days (interquartile range 12‐73 days). Most frequent cancers were gastrointestinal (26.1%), genitourinary (23.3%), and hematological cancer (12.6%). Few had distant metastases (7.1%). At 6 months, recurrent VTE occurred in 6.1% (15.1 events per 100 person‐years) with the highest absolute risks for genitourinary cancer (8.1%), gastrointestinal cancer (7.3%), and breast cancer (6.5%). Major bleeding occurred in 1.9% (5.3 events per 100 person‐years), in particular, in genitourinary cancer (4.5%) and lung cancer (4.2%). Eighty deaths (17.8%) occurred during follow up.ConclusionIn this clinical practice setting, rivaroxaban was rarely used for cancer‐associated VTE. However, among those who received rivaroxaban, the treatment appeared safe and effective with rates comparable to previous studies of selected populations.
Effect of the Co‐SiO2 Mesoporous Layer Coating Step on the Performance of Liquid Fuel Dimethyl Amino Ethyl Azide Dehydration
Authors: Rahimi Elham , Pakdehi Shahram G. , Shafiei Korosh 
Published: February 2019

AbstractA cobalt‐doped silica (Co‐SiO2) layer was successfully synthesized in a sol‐gel process as the mesoporous layer overlaid in three‐, six‐, and ten‐step coating on a mullite support. The microporous layer was coated over the mesoporous layer in six steps by adopting the sol‐gel method. The membranes were applied in pervaporation experiments to dehydrate dimethyl amino ethyl azide (DMAZ) containing 5 wt % water. In dehydration tests, the membrane permeate flux decreased and its separation factor increased. During the first initial hours, it reached a steady state and subsequently remained constant.
Nanosized Composite Pt‐Ru Catalysts for Production of Modern Modified Fuels
Authors: Tungatarova Svetlana , Baizhumanova Tolkyn , Zheksenbaeva Zauresh , Zhumabek Manapkhan , Kaumenova Gulnar , Aubakirov Yermek , Begimova Gulzeynep 
Published: February 2019

AbstractA Pt‐Ru/2 % Ce/(θ+α)‐Al2O3 nanosized catalyst was developed for selective catalytic oxidation of CH4 to synthesis gas. The process was carried out entirely with the formation of synthesis gas at high selectivity by H2 and CO with H2:CO = 2.0 ratio only at Pt:Ru = 2:1 or 1:1 atomic ratio and short contact time on Pt‐, Ru‐, and Pt‐Ru low‐percentage catalysts. Samples, which were reduced by H2 at high temperature, presented a mixture of Pt‐, Ru‐, and Pt‐Ru nanosized particles, its alloy in the mixed catalysts. The correlation between experimental results and data of physicochemical research was established. The activity together with physicochemical properties and quantum chemical calculations for the developed low‐percentage Pt‐Ru catalysts was investigated.
Improvement of Centrifugal Cryoconcentration by Ice Recovery Applied to Orange Juice
Authors: Orellana-Palma Patricio , González Yasna , Petzold Guillermo 
Published: February 2019

AbstractCentrifugal cryoconcentration, a concentration technique employed for fruit juices, involves challenges that still have to be overcome. The improvement of centrifugal cryoconcentration by recovery of ice fractions applied to orange juice is evaluated. The concentration process was performed with three consecutive cryoconcentration cycles and two recirculated ices. The solutes in the concentrated samples increased progressively six times after three cycles compared to the initial concentration of solids. The ice recovery samples increase the overall efficiency of the centrifugal cryoconcentration technique applied to orange juice.
Association between primary language, a lack of mammographic screening, and later stage breast cancer presentation
Authors: Balazy Katy E. , Benitez Cecil M. , Gutkin Paulina M. , Jacobson Clare E. , von Eyben Rie , Horst Kathleen C. 
Published: February 2019

BackgroundHealth determinants are known to influence the stage of breast cancer presentation, but it is unclear to what extent language affects stage. This study investigates whether non–English‐speaking (NES) patients present at a later stage than their English‐speaking (ES) counterparts and whether language is associated with mammographic screening.MethodsThis study was a retrospective, single‐institution cohort analysis of women undergoing breast radiotherapy from 2012 to 2017 (n = 1057). Patients were categorized as ES (n = 904) or NES (n = 153). Ordinal logistic regression analysis identified variables associated with later stage presentation, including language, race/ethnicity, and age. A subcohort analysis investigated the influence of mammographic screening on stage for NES patients.ResultsNES patients had greater odds of later stage disease than ES patients (odds ratio, 1.47; 95% confidence, 1.001‐2.150). This association persisted across all races/ethnicities. An additional analysis examined age categories associated with mammographic screening. For women eligible for screening (ie, those 40‐50 years old or older than 50 years), there was a significant association between language and stage. NES patients older than 50 years were twice as likely to present at an advanced stage in comparison with ES patients (16.19% vs 8.11%;P = .0082). An additional subset analysis accounted for mammograms. NES patients who did not undergo screening had a higher probability of stage III disease (40.3% of NES patients vs 12.7% of ES patients). There was no difference in stage between NES and ES patients who did undergo screening.ConclusionsLanguage is independently associated with later stage breast cancer for NES patients, regardless of race/ethnicity. NES patients may have difficulty in accessing the health care system. Future interventions should seek to reduce language barriers for mammographic screening and diagnosis.
An opcode‐based technique for polymorphic Internet of Things malware detection
Authors: Darabian Hamid , Dehghantanha Ali , Hashemi Sattar , Homayoun Sajad , Choo Kim‐Kwang Raymond 
Published: February 2019

SummaryThe increasing popularity of Internet of Things (IoT) devices makes them an attractive target for malware authors. In this paper, we use sequential pattern mining technique to detect most frequent opcode sequences of malicious IoT applications. Detected maximal frequent patterns (MFP) of opcode sequences can be used to differentiate malicious from benign IoT applications. We then evaluate the suitability of MFPs as a classification feature for K nearest neighbors (KNN), support vector machines (SVM), multilayer perceptron (MLP), AdaBoost, decision tree, and random forest classifier. Specifically, we achieve an accuracy rate of 99% in the detection of unseen IoT malware. We also demonstrate the utility of our approach in detecting polymorphed IoT malware samples.
Challenges introduced by heterogeneous devices for Wi‐Fi–based indoor localization
Authors: Machaj Juraj , Brida Peter , Majer Norbert 
Published: February 2019

SummaryIn the recent time, Wi‐Fi–based indoor positioning attracts a high number of researchers worldwide because of its relatively easy implementation on widely available smart phones. Indoor positioning services can potentially open new markets for service providers and, thus, allow new ways to increase their income. A number of Wi‐Fi–enabled devices have grown significantly as well as coverage of buildings with Wi‐Fi signals, which can be considered ubiquitous nowadays. Recently, there has been a vast number of novel algorithms proposed for Wi‐Fi signals; however, they were mostly tested using only one type of device. In this paper, we will investigate the feasibility of Wi‐Fi–based positioning on different devices and highlight some of the problems that researchers have to face during the proposal of novel positioning algorithms. We have tested different devices in both laboratory and real conditions to see how they perform and which parameters can have a negative impact on the performance of the positioning system.
Monitoring Phenotypic Switching in Candida albicans and the Use of Next‐Gen Fluorescence Reporters
Authors: Frazer Corey , Hernday Aaron D. , Bennett Richard J. 
Published: February 2019

AbstractCandida albicans is an opportunistic human fungal pathogen that is able to cause both mucosal and systemic infections. It is also a frequent human commensal, where it is typically found inhabiting multiple niches including the gastrointestinal tract. One of the most remarkable features of C. albicans biology is its ability to undergo heritable and reversible switching between different phenotypic states, a phenomenon known as phenotypic switching. This is best exemplified by the white‐opaque switch, in which cells undergo epigenetic transitions between two alternative cellular states. Here, we describe assays to quantify the frequency of switching between states, as well as methods to help identify cells in different phenotypic states. We also describe the use of environmental cues that can induce switching into either the white or opaque state. Finally, we introduce the use of mNeonGreen and mScarlet fluorescent proteins that have been optimized for use in C. albicans and which outperform commonly used fluorescent proteins for both fluorescence microscopy and flow cytometry. © 2019 by John Wiley & Sons, Inc.
Does corporate social responsibility affect tax avoidance: Evidence from family firms
Authors: López‐González Eva , Martínez‐Ferrero Jennifer , García‐Meca Emma 
Published: February 2019

AbstractThe purpose of this paper is to shed light on the effect of corporate social responsibility performance on tax avoidance. It also examines whether family ownership affects tax avoidance practices by socially responsible performance. Based on an international sample of 6,442 firm‐year observations from 2006 to 2014, we use several panel‐data regression models. We find that social and environmental performance is negatively related with tax avoidance so that firms with a greater socially responsible performance show a lower tax‐saving practices. However, we find that this negative relation is lower in family‐owned firms, what suggests that despite the fact that family firms show a greater socially responsible behavior aimed to preserve their socioemotional endowments, family ownership is positively associated with tax avoidance practices.
When are internal and external corporate social responsibility initiatives amplified? Employee engagement in corporate social responsibility initiatives on prosocial and proactive behaviors
Authors: Hur Won‐Moo , Moon Tae‐Won , Choi Wook‐Hee 
Published: February 2019

AbstractThe aim of the study is to test not only the relative importance effect of employees' external and internal corporate social responsibility (CSR) perceptions on prosocial and proactive behaviors (i.e., organizational citizenship behavior [OCB] and job crafting) but also the impact of the interaction of these two kinds of employee CSR perceptions on proactive behaviors. Survey‐based data were collected from 181 employees at eight luxury hotels located in South Korea. Using a two‐wave longitudinal design, we measured employees' internal and external CSR perceptions, and then their supervisors rated OCB and job crafting one month after. Hierarchical moderated regression model is employed to test research hypotheses. The results showed that employees' internal CSR perceptions are more strongly related to prosocial and proactive behaviors than employees' external CSR perceptions are. Furthermore, the positive relationship between internal CSR perceptions and prosocial and proactive behaviors was more pronounced when external CSR perceptions were high than when they were low. The theoretical and managerial implications of the results and the limitations of the study are discussed, and future research directions are suggested.
The association between pancreas steatosis and metabolic syndrome: A systematic review and meta‐analysis
Authors: Bi Ye , Wang Ji‐Lan , Li Ming‐Long , Zhou Jie , Sun Xiang‐Lan 
Published: February 2019

AbstractObjectivesPancreas steatosis is the description of fat accumulation in the pancreatic gland. The prevalence and development mechanisms of pancreatic steatosis in patients with metabolic disorders still remain unclear. The aim of this study is to systematically review the association between pancreatic steatosis and metabolic co‐morbidities.MethodsWe performed a systematic search strategy using three electronic databases (MEDLINE, Scopus, and Embase) for relevant studies concerning the associations of pancreatic steatosis with metabolic syndrome (MetS) and its clinical relevance from inception until 30 September 2018.ResultsOne thousand three hundred fifty one references were identified in the initial search, and a total of 13 studies involving 49 329 subjects were included. This analyses elucidated the presence of non‐alcoholic fatty pancreas disease (NAFPD) and was associated with a significant increased risk of metabolic syndrome (RR = 2.25; 95% CI, 2.00‐2.53; P < 0.0001; I2 = 42.8%; eight studies included), hypertension (RR = 1.43; 95% CI, 1.08‐1.90; P = 0.013; I2 = 94.7%; nine studies included), non‐alcoholic fatty liver disease (NAFLD) (RR = 2.49; 95% CI, 2.06‐3.02; P < 0.0001; I2 = 96.9%; nine studies included), diabetes mellitus (RR = 1.99; 95% CI, 1.18‐3.35; P = 0.01; I2 = 97.6%; 10 studies included), and central obesity (RR = 1.91; 95% CI, 1.67‐2.19; P < 0.0001; I2 = 95.9%; six studies included). The association between NAFPD and hyperlipidaemia was not statistically significant (RR = 1.33; 95% CI, 0.82‐2.17; P = 0.249; I2 = 97%; five studies included).ConclusionsThe existing evidence indicates that NAFPD is significantly associated with an increased risk of metabolic syndrome and its components. Well‐designed prospective cohort studies between pancreatic steatosis and MetS are needed to elaborate the causality in the future.