bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rates of female mouse ultrasonic vocalizations are low and are not modulated by estrous state during interactions with muted males
Authors: Malone Cassidy A. , Ziobro Patryk , Khinno Julia , Tschida Katherine A. 
Published: November 2024

AbstractVocalizations produced during courtship can communicate signaler attributes and facilitate mating success. Adult male mice produce high rates of ultrasonic vocalizations (USVs) during courtship interactions with females. For many decades, it was thought that only males produced courtship USVs, but recent studies using microphone arrays to assign USVs to individual signalers report that female mice produce a portion (5-18%) of total courtship USVs. The factors that regulate courtship USV production by female mice are poorly understood. In this study, we tested the idea that female courtship USV production is regulated by estrous state. To facilitate the detection of female USVs, we paired female subjects with males that were muted for USV production via ablation of midbrain neurons that are required for USV production but not for male sexual motivation. We report that total USVs recorded during interactions between group-housed B6 background female mice and muted males are low and are not modulated by female estrous state. Similar results were obtained for single-housed B6 background females and for single-housed outbred wild-derived female mice paired with muted males. These findings suggest either that female mice produce substantial rates of courtship USVs only when interacting with vocal male partners or that prior studies have overestimated female courtship USV production. Studies employing methods that can unambiguously assign USVs to individual signalers, regardless of inter-mouse distances, are needed to distinguish between these possibilities.
Increased reluctant vesicles underlie synaptic depression by GPR55 in axon terminals of cerebellar Purkinje cells
Authors: Inoshita Takuma , Kawaguchi Shin-ya 
Published: November 2024

AbstractControl of synaptic transmission efficacy by neuronal activity and neuromodulators is pivotal for brain function. Synaptic suppression by cannabinoids activating CB1 receptors has been extensively studied at the molecular and cellular levels to understand the neuronal basis for symptoms of cannabis intake. Here, we focused on another type of cannabinoid receptor GPR55, which shows sensitivity to cannabidiol, a chemical included in cannabis, aiming to highlight its actions on presynaptic function. Taking advantage of direct patch-clamp recordings from axon terminals of cerebellar Purkinje cells together with fluorescent imaging of vesicular exocytosis using synapto- pHluorin, we show that GPR55 suppresses synaptic transmission as CB1 receptor does, but through a distinct presynaptic modulation of release machinery. Activation of GPR55 reduced transmitter release by changing neither presynaptic action potential waveform nor Ca2+influx, but by making a large population of Ca2+-responsive synaptic vesicles insensitive to Ca2+influx through voltage-gated Ca2+channels, leading to substantial reduction of the readily releasable pool of vesicles. Thus, the present study identifies a unique mechanism to suppress presynaptic transmitter release by atypical receptor for cannabinoid, which would enable subtype-specific modulation of neuronal computation by cannabinoid receptors.
Intuitive physical reasoning is not mediated by linguistic nor exclusively domain-general abstract representations
Authors: Kean Hope , Fung Alexander , Pramod RT , Chomik-Morales Jessica , Kanwisher Nancy , Fedorenko Evelina 
Published: November 2024

AbstractThe ability to reason about the physical world is a critical tool in the human cognitive toolbox, but the nature of the representations that mediate physical reasoning remains debated. Here, we use fMRI to illuminate this question by investigating the relationship between the physical-reasoning system and two well-characterized systems: a) the domain-general Multiple Demand (MD) system, which supports abstract reasoning, including mathematical and logical reasoning, and b) the language system, which supports linguistic computations and has been hypothesized to mediate some forms of thought. We replicate prior findings of a network of frontal and parietal areas that are robustly engaged by physical reasoning and identify an additional physical-reasoning area in the left frontal cortex, which also houses components of the MD and language systems. Critically, direct comparisons with tasks that target the MD and the language systems reveal that the physical-reasoning system overlaps with the MD system, but is dissociable from it in fine-grained activation patterns, which replicates prior work. Moreover, the physical-reasoning system does not overlap with the language system. These results suggest that physical reasoning does not rely on linguistic representations, nor exclusively on the domain-general abstract reasoning that the MD system supports.
Coupled aging of cyto- and myeloarchitectonic atlas-informed gray and white matter structural properties
Authors: Hoagey David A. , Pongpipat Ekarin E. , Rodrigue Karen M. , Kennedy Kristen M. 
Published: November 2024

ABSTRACTA key aspect of brain aging that remains poorly understood is its high regional heterogeneity and heterochronicity. A better understanding of how the structural organization of the brain shapes aging trajectories is needed. Neuroimaging tissue “types” are often collected and analyzed as separate acquisitions, an approach that cannot provide a holistic view of age-related change of the related portions of the neurons (cell bodies and axons). Because neuroimaging can only assess indirect features at the gross macrostructural level, incorporating post-mortem histological information may aid in better understanding of structural aging gradients. Longitudinal design, coupling of gray and white matter (GM, WM) properties, and a biologically informed approach to organizing neural properties are needed. Thus, we tested aging of the regional coupling between GM (cortical thickness, surface area, volume) and WM (fractional anisotropy, mean, axial, and radial diffusivities) structural metrics using linear mixed effects modeling in 102 healthy adults aged 20-94 years old, scanned on two occasions over a four-year period. The association between age-related within-person change in GM morphometry and the diffusion properties of the directly neighboring portion of white matter were assessed, capturing both aspects of neuronal health in one model. Additionally, we parcellated the brain utilizing the histological-staining informed von Economo-Koskinas atlas to consider regional cyto- and myelo-architecture. Results demonstrate several gradients of coupled association in the age-related decline of neighboring white and gray matter. Most notably, gradients of coupling along the heteromodal association to sensory axis were found for several areas (e.g., anterior frontal and lateral temporal cortices, vs pre- and post-central gyrus, occipital, and limbic areas), in line with heterochronicity and retrogenesis theories of aging. Further effort to bridge across data and measurement scales will enhance understanding of the mechanisms of the aging brain.
Hadronic decay of exotic mesons consisting of four charm quarks
Authors: Zhang Hong-Fei , Mo Xue-Mei , Yan Yu-Peng 
Published: November 2024

In 2020, a di-J/ψ resonance centered at around 6.9 GeV was discovered by the LHCb Collaboration and was later confirmed by the ATLAS and CMS Collaborations. In addition to the 6.9-GeV resonance, its low-energy counterpart centered at around 6552 MeV was also observed by the CMS Collaboration. They are generally considered as fully charm tetraquarks. In this paper, we calculate the inclusive decay width of molecules composed of two J/ψ’s and genuine fully charm tetraquarks into light hadrons and into open charms, respectively. Assuming them as S-wave states, we consider all possible spin configurations, namely, spin-0 and spin-2, that decay exclusively into double J/ψ, and find that the ratio (R) of the decay width for the light-hadron final states to that for the charmed final states differs significantly among different spin configurations, which can help to explore the nature of the observed di-J/ψ resonances.

Published by the American Physical Society
2024
A diffusion of innovation (DOI) analysis of 3D food printing adoption among food sector early adopters
Authors: Guaqueta-Garcia Daniela Juliana , Wolodko John , Wismer Wendy 
Published: November 2024

PurposeResearch on 3DFP has focused on technical developments and consumer acceptance, but the practical implications of adopting this technology from industry perspectives across food sectors are underexplored. This study aimed to uncover factors influencing 3DFP adoption and the prospects of this technology by interviewing food businesses using 3DFP in different food sectors around the globe.Design/methodology/approachThe Diffusion of Innovation (DOI) model, a process-oriented adoption approach, was utilized to understand the technological, adopter and social factors influencing 3DFP adoption in food businesses.FindingsDecisions to adopt 3DFP hinged on technology compatibility with business needs, adopters’ innovation and technology interests and perceived public interest. Early adoption cases revealed 3DFP benefits over conventional technologies in improved product design, customization, food versatility, convenience and sustainability. Interconnected barriers to adoption included high investment costs, limited technology capacity, negative consumer perception and a low adoption rate by large companies. Proposed barrier solutions by businesses encompassed improving technology scalability and leveraging food and technology familiarity alongside alternative technology labelling to increase visibility and interest by large companies and consumers.Originality/valueTo the best of the authors’ knowledge, this is the first study assessing the determinants of early adopting 3DFP, covering perspectives from different food sectors and using the DOI model. The study’s insights are valuable for food industry stakeholders: policymakers, industry leaders, food businesses and researchers. It can guide subsequent adopters’ decision-making and inform future research on technical, social and business aspects to enhance adoption in the promissory food sectors for 3DFP such as protein alternatives.
Rich and fat? Isolating the causal effect of obesity on income among Chinese rural residents by Mendelian randomization
Authors: Xu Wenyan , Zhao Qiran , Si Wei , Zhu Chen 
Published: November 2024

PurposeWhile the adverse health consequences of obesity are well-documented, the causal effect between obesity and economic outcomes, particularly individual income in the labor market, has yielded inconsistent findings. At the same time, China has the highest number of obese or overweight people around the world in recent years. However, limited research has examined the causal effect of obesity on Chinese rural residents’ income. To answer this question, our study aims to identify the causal impact of obesity on Chinese rural residents.Design/methodology/approachFirst, we conduct ordinary least squares, instrumental variable and Mendelian randomization methods to evaluate the impact of obesity on Chinese rural residents’ income. Then, we employ quantile regression and instrumental variable quantile regression to investigate the potential distributional impacts of obesity across various income segments. For the generality of our results, we also use 485,849 samples from the UK Biobank and the two-sample Mendelian randomization method to analyze.FindingsOur one-sample Mendelian randomization analysis, based on a sample of 441 people collected from rural China in 2019 and 2021, revealed that obesity reduced residents’ annual income by 647.87 China Yuan. Results from the UK further support our findings. We also find that the adverse causal impact of obesity on income is significant in individuals within the above 50th percentile of the income distribution. Additionally, childhood obesity has a long-term adverse effect on income in adulthood.Research limitations/implicationsThese results contribute to a more nuanced understanding of the economic costs of obesity. Weight penalties may lead to a deviation from the efficiency that should be pursued in the labor market and widen income disparity.Originality/valueWe provide novel and robust instrumental variables and utilize the Mendelian randomization method to analyze the effect of obesity on Chinese rural residents.
CEO trustworthiness and investment efficiency: evidence from China
Authors: Ullah Irfan , Shah Syed Hamid Ali , Zeb Aurang 
Published: November 2024

Purpose
This study aims to investigate the influence of chief executive officer (CEO) trustworthiness on firm investment efficiency and explores how this relationship varies in different contexts, including product market competition (PMC), institutional investors, media coverage, analyst monitoring and ownership structure.

Design/methodology/approach
The authors examined a sample of A-Share non-financial firms listed on the Shanghai and Shenzhen Stock Exchanges from 2005–2018 by using panel date regression techniques. The robustness of the findings is affirmed through alternative measures of investment efficiency and various econometric techniques. Further, various endogeneity tests are conducted to confirm that the findings are not affected by potential bias.

Findings
The authors find a significant positive effect of CEO trustworthiness on firms’ investment efficiency and exhibit that CEO trustworthiness mitigates the issue of underinvestment rather than overinvestment. Further, PMC strengthens the association between CEO trustworthiness and investment efficiency. The influence is more pronounced when institutional investors, media and analyst monitoring are low and in non state-owned firms. Likewise, financial reporting quality is found to be an underlying mechanism for the positive association between CEO trustworthiness and investment efficiency.

Research limitations/implications
The reliance on a location-specific index of CEO trustworthiness may obscure its true nature, and caution is warranted when generalizing these results to other regions.

Practical implications
This study suggests that elevating a trustworthy CEO to the firm upper echelon can improve investment efficiency. Policymakers and investors should recognize and leverage the effect of CEO trustworthiness in firms, especially those with weaker governance structures.

Originality/value
This study enriches the literature about investment efficiency by introducing a novel determinant, CEO trustworthiness and establishes that it acts as an informal social institution that improves firms’ resource utilization in emerging economies with weak governing structures.
ISRO: moving heaven and earth to put humans in space
Authors: Ghosal Debraj , Krishna Malay 
Published: November 2024

Learning outcomes
This case study can be used to highlight aspects of classic strategic management, such as industry analysis as well as cost leadership strategy, in the context of the space industry. After working through the case study and assignment questions, the students will be able to identify industry dynamics in a high-tech industry (space), examine the strategy of a focal organisation, in light of external and internal factors, evaluate the decision-making process behind adopting new technology and whether the strategic motivations for competing with global players are justified and develop recommendations to help an organisation in achieving its strategic goals.

Case overview/synopsis
This case study outlines the remarkable success of the Indian Space Research Organisation (ISRO), as well as the formidable challenges facing its chairperson, S. Somanath. While Somanath could point to major recent successes – ISRO’s picture perfect landing near the moon’s south pole, and successful deployment of a solar probe – he could also see two formidable missions ahead. First, there was Gaganyaan, India’s first human spaceflight, which had already slipped its launch schedule a couple of times. Second was the mission to establish a space station by 2035. The first mission had been plagued by delays due to the long process of developing technology indigenously, as international technology transfer at an affordable price was not forthcoming. The second mission required ISRO to develop an ability to keep humans in space indefinitely, which again required acquisition of new technology. In addition, ISRO’s service of launching satellites in low Earth orbit was threatened by SpaceX, which delivered similar service at a much lower cost due to a new reusable rocket technology. In response to the new challenges, Somanath had accelerated collaboration with Indian private sector companies, including start-ups. The goal was to outsource and expand ISRO’s rocket development and launch capability. While the outsourcing might free up ISRO’s capacity, the technology and knowhow development required would still take a while to develop from scratch. Hence, Somanath (and learners) need to consider: What other strategic options might ISRO consider to adapt to the dynamics of the space economy?

Complexity academic level
This case study is suitable for courses in MBA/Masters.

Supplementary materials
Teaching notes are available for educators only.

Subject code
CSS 11: Strategy.
Blockchain-enabled value creation for circular supply chain in the tyre industry
Authors: Modgil Sachin , Singh Rohit Kumar 
Published: November 2024

PurposeMade-in-India tyres are rapidly integrating into global supply chains due to a globally coordinated regulatory environment and aspiring for value creation and contribution to circularity. However, it is not clear what are the constituent components of emerging technologies like blockchain that can facilitate value creation and how they are associated. Therefore, this study intends to explore the elements of blockchain technology and how they create value to bring circularity to a tyre supply chain.Design/methodology/approachThis study employed a survey-based quantitative methodology to test the theoretical framework of blockchain-enabled circular supply chains using non-parametric regression analysis. A total of 307 responses from India-based supply chain professionals’ data were collected from September 2022 to January 2023 to perform non-parametric regression analysis.FindingsThe results indicated that blockchain could improve visibility and accessibility by having value-creation capabilities of data collection, monitoring, processing and analysis to facilitate the circular tyre supply chain which focuses on recycling, reusing, reducing and rethinking initiatives. Further, accessibility contributes more than visibility to creating value toward a blockchain-enabled tyre circular supply chain.Originality/valueFirst, this study employs a grounded theory-driven approach in identifying and testing a framework through hierarchical regression. This study identifies the role of blockchain technology in unfolding visibility and accessibility towards value creation, enhancing circularity in the supply chains in complex and critical industries such as tyres in India and across the globe.
Does CEO age matter in auditor choice and audit pricing? The role of CEO dominance
Authors: Ferdous Lutfa Tilat , Bose Sudipta , Shams Syed , Azizkhani Masoud 
Published: November 2024

PurposeThis study examines the impact of the age of the chief executive officer (CEO) on the demand for audit quality, as reflected in auditor choice and audit fees. Furthermore, the study investigates whether CEO dominance moderates the association between CEO age, auditor choice and audit fees.Design/methodology/approachUsing a sample of 14,066 firm-year observations from 2000 to 2017, the study employs logistic regression and ordinary least squares (OLS) regressions to estimate the research models. The study also employs various techniques to address the endogeneity issue in the findings.FindingsUsing industry specialist auditors and brand name (Big 4) auditors as proxies, the study finds that firms with older CEOs are more likely to appoint higher-quality auditors. The study also finds that firms with older CEOs pay higher audit fees than firms with younger CEOs, which is likely to be due to increased demand for higher-quality audits and to risk aversion among older CEOs. In addition, the study finds that CEO dominance attenuates the positive association of CEO age with auditor choice and audit fees. The findings are found to be robust in our analyses, which address the endogeneity issue with firm fixed effects, two-stage least squares (2SLS) regression and entropy balancing. In addition, the study provides evidence that the positive association between CEO age and audit pricing persists when firms replace younger CEOs with older CEOs.Research limitations/implicationsThe study’s findings suggest that the United States (US) Securities and Exchange Commission (SEC) and the Public Company Accounting Oversight Board (PCAOB) may need to be more cautious when monitoring financial statements from firms with younger CEOs.Originality/valueThis study contributes to a growing stream of research investigating the links between managers’ idiosyncratic age differences and the quality of financial reporting and corporate decisions.
Understanding users’ trust transfer mechanism in food delivery apps
Authors: Mai Xuan Tai , Nguyen Trang 
Published: November 2024

PurposeDrawing upon the trust transfer theory and IS success model, this study investigates the transfer mechanism and the antecedents of trust to the platform and trust to a food vendor in the FDA, which subsequently affect users’ behavioral intention.Design/methodology/approachData collection was carried out through an online questionnaire via the Prolific platform. Respondents were exclusively selected from Uber Eats users in the US market due to the popularity of this food delivery app and the volume of food delivery transactions in this country.FindingsThe findings confirmed the trust transfer between trust in the platform and trust in the food vendor, ultimately contributing to users’ continuance usage intention and purchase intention. Our empirical results also show that system quality and service quality lead to trust-in-platform, while product presentation richness, vendor reputation and social referrals enhance trust in food vendors.Practical implicationsThe results offer valuable insights for FDA providers and food vendors to offer better user experiences to foster trust, enhance purchase intention and retain their commitment to the platform.Originality/valueUnlike past research in an e-commerce context that mainly concentrates on the role of trust in general or trust in the platform, this study expands the understanding of trust-related research by exploring the predictors and consequences of both trust toward the platform and trust toward the vendors in the FDA settings.