bluuebunny/crossref_metadata_2025_split huggingface dataset:
5-Year review on amniocentesis and its maternal fetal complications
Authors: Jummaat Fauziah , Ahmad Shuhaila , Mohamed Ismail Nor Azlin 
Published: September 2019

Abstract

Background
Amniocentesis is a well-known invasive procedure which is commonly carried out in the second trimester. The indication for amniocentesis varies throughout countries and centers. Despite providing significant prenatal diagnosis; many maternal and fetal complications have been reported from previous studies.

Materials and methods
This retrospective study aimed to determine the maternal and fetal complications following amniocentesis. This study involved all patients who underwent amniocentesis from January 2012 until June 2017 in a tertiary centre. Maternal age, parity, premorbid medical conditions, amniocentesis indications, gestational age during amniocentesis, karyotyping results, complications during and post procedure and the fetal outcomes were reviewed and analyzed.

Results
One hundred and fourteen patients’ medical records were reviewed and the majority of patients (50.9%) ranged in age from age 30 to 39 years old with mean age of 34.29 years. Amniocentesis was performed during the second trimester in the majority of patients (71.1%). The indications for amniocentesis in this study were polyhydramnios (7.9%), advanced maternal age (9.6%), risk of Down’s syndrome (31.6%), increased risk of Patau syndrome (6.1%), increased risk of Edward’s syndrome (4.4%) and abnormal fetal ultrasonography (70.2%). Cytogenetics results of amniocentesis were normal in 82 patients (71.9%). The majority of patients (86.0%) had no complications. Two patients (12.5%) had intrauterine death presumed to be procedural related.

Conclusion
This 5-year retrospective study on amniocentesis procedure showed that the majority of amniocentesis were safe as 86.0% of the patients were free from any complications. Anticipating its complication is important as there is always a risk even though it is a safe procedure in general.
Structural investigations of cell-free expressed G protein-coupled receptors
Authors: Kögler Lisa Maria , Stichel Jan , Beck-Sickinger Annette G. 
Published: September 2019

Abstract
G protein-coupled receptors (GPCRs) are of great pharmaceutical interest and about 35% of the commercial drugs target these proteins. Still there is huge potential left in finding molecules that target new GPCRs or that modulate GPCRs differentially. For a rational drug design, it is important to understand the structure, binding and activation of the protein of interest. Structural investigations of GPCRs remain challenging, although huge progress has been made in the last 20 years, especially in the generation of crystal structures of GPCRs. This is mostly caused by issues with the expression yield, purity or labeling. Cell-free protein synthesis (CFPS) is an efficient alternative for recombinant expression systems that can potentially address many of these problems. In this article the use of CFPS for structural investigations of GPCRs is reviewed. We compare different CFPS systems, including the cellular basis and reaction configurations, and strategies for an efficient solubilization. Next, we highlight recent advances in the structural investigation of cell-free expressed GPCRs, with special emphasis on the role of photo-crosslinking approaches to investigate ligand binding sites on GPCRs.
Developing Reflective Thinking through Poetry Writing: Views from Students and Educators
Authors: Jack Kirsten , Illingworth Sam 
Published: September 2019

Abstract
Aims and Objectives To explore student nurse and educator perspectives on the use of poetry writing as a way to reflect on important nursing practice issues. Background Reflective practice is a well-established method of learning in pre-registration nurse education although student nurses can find reflection a challenging process. Design An exploratory descriptive approach. Methods Data were extracted from unstructured interviews with students and educators (n = 12) from one university in the North-West region of England, United Kingdom (UK). Data were thematically analysed. Results Poetry writing supports a meaningful exploration of events, which have the potential to lead to changes in perspective. Careful planning of the poetry writing process is required, to ensure the potential of this approach is realised. Conclusion Poetry writing is an effective way to reflect on clinical practice. This work has relevance and transferability to a wide range of professional disciplines, where reflective practice is encouraged.
Reflecting on Leadership Development through Community Based Participatory Action Research
Authors: Asirifi Mary Asor 
Published: September 2019

Abstract
The need for leadership in nursing is well-documented and Domain Six of the doctoral section of the National Nursing Education Framework of the Canadian Association of Schools of Nursing (CASN) is Leadership. While there are likely many paths to achievement of these leadership components, the intent of this paper is to share my journey through iteration of and reflection on my PhD dissertation research focused on a four-cycle community-based participatory action research study (CBPR) related to clinical teaching in Ghana. The focus of CBPR is to engage the researcher and the participant group (community) in collaborative, and egalitarian processes to assess and problem solve an issue in the community. Similarly, leadership promotes collaborative interpersonal relationships among leaders and followers to address issues and institutes change strategies in policies. This paper presents my experiences in building leadership capacity through this scholarly endeavor (PhD thesis) in relation to the CASN guideline.
Enhanced Twitter Sentiment Analysis Using Hybrid Approach and by Accounting Local Contextual Semantic
Authors: Gupta Itisha , Joshi Nisheeth 
Published: September 2019

Abstract
This paper addresses the problem of Twitter sentiment analysis through a hybrid approach in which SentiWordNet (SWN)-based feature vector acts as input to the classification model Support Vector Machine. Our main focus is to handle lexical modifier negation during SWN score calculation for the improvement of classification performance. Thus, we present naive and novel shift approach in which negation acts as both sentiment-bearing word and modifier, and then we shift the score of words from SWN based on their contextual semantic, inferred from neighbouring words. Additionally, we augment negation accounting procedure with a few heuristics for handling the cases in which negation presence does not necessarily mean negation. Experimental results show that the contextual-based SWN feature vector obtained through shift polarity approach alone led to an improved Twitter sentiment analysis system that outperforms the traditional reverse polarity approach by 2–6%. We validate the effectiveness of our hybrid approach considering negation on benchmark Twitter corpus from SemEval-2013 Task 2 competition.
Mechanical characterization and machining performance evaluation of rice husk/epoxy an agricultural waste based composite material
Authors: Jain Naman , Somvanshi Kritika Singh , Gope Prakash Chandra , Singh V. K. 
Published: September 2019

AbstractNatural fibers from agricultural waste have received more attraction than traditional synthetic fibers in recent years. In present investigation epoxy/rice husk composite has been fabricated to utilize the agricultural waste which can be recycled easily and overcome the pollution problems due to smoke and fine silica ash. Study of interfacial bonding and dispersion of rice husk in epoxy resin has been studied through scanning electron microscope image. Characterization of fabricated composites has been done by mechanical properties. Ultimate tensile strength, Young’s Modulus and hardness are highest at 10 wt.% of rice husk particle and their values are 66.5 MPa, 616.46 MPa and 16.8 HV respectively. Machinability of epoxy/rice husk composites has been determined through drilling operation. Effect of feed rate (0.1, 0.2 and 0.3 mm/rev), speed (300, 600 and 900 rpm) and wt.% of reinforcement (10, 15 & 20) have been studied on machinability of epoxy/rice husk composites. Taguchi L27orthogonal array has been applied to conduct the experiments to evaluate the performance characteristics viz thrust force and torque. Weight percentage was found the most significant factor for machinability followed by feed rate and speed.
The non-commuting graph of a non-central hypergroup
Authors: Iranmanesh Mahdiyeh , Jafarpour Morteza , Cristea Irina 
Published: September 2019

Abstract
The aim of this paper is to construct and study the properties of a certain graph associated with a non-central hypergroup, i.e. a hypergroup having non-commutative the associated fundamental group. The method of the construction of the graph is similar to that one proposed by Paul Erdős, when he defined a graph associated with a non-commutative group. We establish necessary and /or sufficient conditions for the associated graph to be Hamiltonian or planar.
Evaluation of surgical site infection in mini-invasive urological surgery
Authors: de Vermandois Jacopo Adolfo Rossi , Cochetti Giovanni , Zingaro Michele Del , Santoro Alberto , Panciarola Mattia , Boni Andrea , Marsico Matteo , Gaudio Gianluca , Paladini Alessio , Guiggi Paolo , Cirocchi Roberto , Mearini Ettore 
Published: September 2019

Abstract
Surgical Site Infection (SSI) is the most frequent source of infection in surgical patients and the second most frequent cause of hospital-acquired infection. The primary aim of this prospective study was to compare SSI occurrences between minimally invasive surgery (MIS) and open urological surgery. Secondly, perioperative outcomes were evaluated in two different approaches.
A consecutive group of 60 patients undergoing urological surgery were prospectively enrolled in a single high-volume center between May and October 2018. We included procedures that were performed by minimally invasive or traditional techniques. We evaluated and compared the incidence of SSI and perioperative outcomes in terms of intraoperative bleeding, post-operative complications, postoperative pain, patient satisfaction with the analgesic treatment, time to flatus, time of oral intake and mobilization, and length of hospital stay. The two groups were homogeneous with regard to demographic data.
Superficial incisional SSIs were diagnosed in 10% of cases (3/30) in the second group and 0% in the first (p<0.05); space/organ SSIs developed in 4 patients, which were diagnosed by ultrasound scan and confirmed by abdominal CT: 1 patient (3.3%) in group 1 showed an infected lymphocele, whereas 1 case of infected lymphocele and 2 cases of pelvic abscess were detected in group 2 (10%, p<0.05). All the perioperative outcomes as well as were overall complication rate favored MIS (p<0.05). The use of minimally invasive techniques in urological surgery reduced the risk of SSI by comparison with a traditional approach. In addition, MIS was associated with better perioperative outcomes and a lower overall complication rate.
Optical force microscopy: combining light with atomic force microscopy for nanomaterial identification
Authors: Jahan Nusrat , Wang Hanwei , Zhao Shensheng , Dutta Arkajit , Huang Hsuan-Kai , Zhao Yang , Chen Yun-Sheng 
Published: September 2019

Abstract
Scanning probe techniques have evolved significantly in recent years to detect surface morphology of materials down to subnanometer resolution, but without revealing spectroscopic information. In this review, we discuss recent advances in scanning probe techniques that capitalize on light-induced forces for studying nanomaterials down to molecular specificities with nanometer spatial resolution.
Crystal structure of tetraaqua-bis(μ2-5-aminoisophthalato-κ3
N:O,O′)-bis(4,4′-dipyridylsulfide-κ1
N)dizinc(II), C36H34N6O12S2Ni2
Authors: Chang Xin-Hong , Zhai Zhi-Min , Lu Xiao-Min 
Published: September 2019

Abstract
C36H34N6O12S2Ni2, monoclinic, C2/c (no. 15), a = 29.642(4) Å, b = 6.2241(4) Å, c = 21.667(2) Å, β = 108.592(13)°, V = 3788.9(7) Å3, Z = 4, R
gt(F) = 0.0907, wR
ref(F
2) = 0.1605, T = 293(2) K.
Barrel heating with inductive coils in an injection molding machine
Authors: Nian Shih-Chih , Yeh Gao-Hao , Huang Ming-Shyan 
Published: September 2019

Abstract
Traditional injection molding machines use resistance heating (RH) bands to heat the barrel. However, RH has a low energy rate; thus, the time required to reach the target temperature is rather long. Consequently, the use of inductive techniques, with a faster heating rate and improved energy rate, has attracted growing interest in recent years. However, an inappropriate design of the inductive coils and plasticization barrel may result in a strong repulsive magnetic field between neighboring coils and a corresponding reduction in the heating performance. Thus, developing an appropriate inductive heating design is essential in improving the barrel heating performance. The present study therefore performed a simulation and experimental investigation into the magnetic field and temperature distribution for different barrel geometries and coil current designs. The simulation results showed that the application of spiral grooves to the barrel improved both the heating rate and the temperature uniformity (TU) and effectively solved the proximity effect. The results indicated that the application of induction heating together with a novel grooved barrel design yields an effective improvement in both the thermal efficiency and the TU compared to that achieved using the traditional RH method with a single- or double-section barrel.
Determining wildland fire markers in residential structures using thermal desorption gas chromatography mass spectrometry
Authors: Martin M. Katie , LeCaptain Dale J. , Delia Alice 
Published: September 2019

Abstract
Each year thousands of wildland fires blaze across the United States causing secondary (“smoke”) damage to numerous businesses and personal property. Currently there are no specific industry standards or guidelines for determining wildfire combustion residues. Remediation decisions often rely on anecdotal evidence from occupants. A variety of particulate methods are used to assess surface contamination but there are few methods for evaluating organic chemical residues that encompass the wide range of chemical classes produced during wildland fires. A new method was developed employing a thermal desorption gas chromatography mass spectrometry (TD-GCMS). TD-GCMS using novel sorbent beds decreases the sample preparation substantially and enables sampling of bulk materials by off-gassing. Furthermore, the method developed is specific to wildland fire events. Results from a simulated wildland fire event are also provided.
Nuclear Receptor Nr4a1 Regulates Striatal Striosome Development and Dopamine D1Receptor Signaling
Authors: Cirnaru Maria-Daniela , Melis Chiara , Fanutza Tomas , Naphade Swati , Tshilenge Kizito-Tshitoko , Muntean Brian S. , Martemyanov Kirill A. , Plotkin Joshua L. , Ellerby Lisa M. , Ehrlich Michelle E. 
Published: September 2019

AbstractThe GABAergic medium-size spiny neuron (MSN), the striatal output neuron, may be classified into striosome, also known as patch, and matrix, based on neurochemical differences between the two compartments. At this time, little is known regarding the regulation of the development of the two compartments.Nr4a1, primarily described as a nuclear receptor/immediate early gene involved in the homeostasis of the dopaminergic system, is a striosomal marker. UsingNr4a1-overexpressing andNr4a1-null mice, we sought to determine whether Nr4a1 is necessary and/or sufficient for striosome development. We report thatin vivoandin vitro,Nr4a1andOprm1mRNA levels are correlated. In the absence of Nr4a, there is a decrease in the percentage of striatal surface area occupied by striosomes. Alterations inNr4a1expression leads to dysregulation of multiple mRNAs of members of the dopamine receptor D1signal transduction system. Constitutive overexpression ofNr4a1decreases both the induction of phosphorylation of ERK after a single cocaine exposure and locomotor sensitization following chronic cocaine exposure.Nr4a1overexpression increases MSN excitability but reduces MSN long-term potentiation. In the resting state, type 5 adenylyl cyclase (AC5) activity is normal, but the ability of AC5 to be activated by Drd1 G-protein-coupled receptor inputs is decreased. Our results support a role forNr4a1in determination of striatal patch/matrix structure and in regulation of dopaminoceptive neuronal function.
Dickens’s Tableaux
Authors: Wiet Victoria 
Published: September 2019

Victoria Wiet, “Dickens’s Tableaux: Melodrama and Sexual Opacity in David Copperfield and Bleak House” (pp. 167–198)
This essay examines the features and function of tableaux in two novels by Charles Dickens, David Copperfield (1850) and Bleak House (1853), in order to rethink the influence of melodramatic conventions on the form of narrative fiction, particularly the understanding of female sexuality that melodrama afforded novelists. Taking Dickens as an important example, literary critics have typically associated melodrama with ostentatious legibility, but recent scholarship on the theatrical tableau has illuminated the complex ways the melodramatic stage both produced and occluded revelation. Drawing on this work, I demonstrate that the adaptation of the tableau into the novel form increases the possibility of illegibility because readers necessarily rely on the narrator’s description and interpretation of the material world. In David Copperfield and Bleak House, this remediation has particularly significant consequences for the representation of sexually compromised women. By inadequately revealing the sexual histories of suspected “fallen women,” densely visual but opaque scenes featuring Annie Strong, Martha Endell, and Honoria Dedlock defer judgment on their characters, with Lady Dedlock’s protracted illegibility preventing her plot from culminating in a decisive narrative or moral conclusion. Because the narrators of both novels depict these female characters as deliberately making themselves illegible, the novel tableau becomes an important way for Dickens to dramatize the fallibility of the omniscient and quasi-omniscient narrators of realist fiction.
“He Resembled the Great Emperor”
Authors: Heitzman Matthew 
Published: September 2019

Matthew Heitzman, “‘He Resembled the Great Emperor’: Charlotte Brontë, Villette, and the Rise of Napoleon III” (pp. 199–223)
This essay offers a local historical context for Charlotte Brontë’s Villette (1853), reading it in relation to the rise of Napoleon III as Emperor of France. Napoleon III completed his ascendancy just as Brontë was completing her novel. His rise prompted a mixture of anxiety and optimism in the English press, as English political commentators were uncertain if this new Napoleon’s reign would mark a return to the Anglo-French nationalist strife of the first Napoleonic period or if his rule would mark a détente and productive path forward for Anglo-French relations. I argue that this ambiguity is coded into Brontë’s characterization of Monsieur Paul Emanuel, and that we can read Monsieur Paul’s romance with Lucy Snowe as a political allegory—Brontë’s attempt to decipher what Napoleon III’s rapid rise meant for Anglo-French relations. I suggest in this essay that Brontë’s interest in the contemporary Anglo-French political context was a product of her fascination with Napoleon Bonaparte, specifically his rivalry with the Duke of Wellington, and that understanding her interest in the first Napoleonic period can help us to decipher why her depiction of Anglo-French nationalist interaction in Villette is totally at odds with her other novels, where French nationalism is typically a trait that needs to be effaced.
Early diagnosis of gestational diabetes mellitus using circulating microRNAs
Authors: Yoffe Liron , Polsky Avital , Gilam Avital , Raff Chen , Mecacci Federico , Ognibene Agostino , Crispi Fatima , Gratacós Eduard , Kanety Hannah , Mazaki-Tovi Shali , Shomron Noam , Hod Moshe 
Published: September 2019

Design
Gestational diabetes mellitus (GDM) is one of the most common pregnancy complications and its prevalence is constantly rising worldwide. Diagnosis is commonly in the late second or early third trimester of pregnancy, though the development of GDM starts early; hence, first-trimester diagnosis is feasible.

Objective
Our objective was to identify microRNAs that best distinguish GDM samples from those of healthy pregnant women and to evaluate the predictive value of microRNAs for GDM detection in the first trimester.

Methods
We investigated the abundance of circulating microRNAs in the plasma of pregnant women in their first trimester. Two populations were included in the study to enable population-specific as well as cross-population inspection of expression profiles. Each microRNA was tested for differential expression in GDM vs control samples, and their efficiency for GDM detection was evaluated using machine-learning models.

Results
Two upregulated microRNAs (miR-223 and miR-23a) were identified in GDM vs the control set, and validated on a new cohort of women. Using both microRNAs in a logistic-regression model, we achieved an AUC value of 0.91. We further demonstrated the overall predictive value of microRNAs using several types of multivariable machine-learning models that included the entire set of expressed microRNAs. All models achieved high accuracy when applied on the dataset (mean AUC = 0.77). The significance of the classification results was established via permutation tests.

Conclusions
Our findings suggest that circulating microRNAs are potential biomarkers for GDM in the first trimester. This warrants further examination and lays the foundation for producing a novel early non-invasive diagnostic tool for GDM.
Demanda agregada y desigualdad regional por género en México
Authors: Ayala Gaytán Edgardo Arturo , Chapa Cantú Joana Cecilia 
Published: September 2019

Se propone una técnica de descomposición estructural que permite descomponer el ingreso laboral de hombres y mujeres en cuatro regiones de México, vinculado a una expansión en la demanda final en tres efectos: nacional, regional y tecnológico. Los resultados indican que los multiplicadores del ingreso de las mujeres son relativamente altos en servicios. El consumo del Gobierno es el que impacta más el ingreso de las mujeres; en cambio, la expansión de la inversión favorece más el ingreso de los hombres. Los índices de equidad de género regionales son poco sensibles a expansiones en la demanda final.