bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developmental pathways from child maltreatment to adolescent suicide-related behaviors: The internalizing and externalizing comorbidity hypothesis
Authors: Duprey Erinn Bernstein , Oshri Assaf , Liu Sihong 
Published: August 2019

AbstractChild maltreatment is a robust risk factor for suicidal ideation and behaviors during adolescence. Elevations in internalizing and externalizing symptomology have been identified as two distinct developmental pathways linking child maltreatment and adolescent risk for suicide. However, recent research suggests that the co-occurrence of internalizing and externalizing symptomology may form a distinct etiological pathway for adolescent risk behaviors. Using the Longitudinal Studies on Child Abuse and Neglect (LONGSCAN) sample (N= 1,314), the present study employed a person-centered approach to identify patterns of concurrent change in internalizing and externalizing psychopathology over five time points from early childhood to adolescence in relation to previous experiences of child maltreatment and subsequent suicidal ideation and behaviors. Results indicated four distinct bivariate externalizing and internalizing growth trajectories. Group membership in a heightened comorbid internalizing and externalizing symptom trajectory mediated the association between childhood abuse and adolescent suicidal ideation and suicidal behaviors. These findings suggest that the concurrent development of externalizing and internalizing symptoms in childhood and adolescence may constitute a unique developmental trajectory that confers risk for suicide-related outcomes.
Glucocorticoid receptor signaling in leukocytes after early life adversity
Authors: Elwenspoek Martha M. C. , Hengesch Xenia , Leenen Fleur A. D. , Sias Krystel , Fernandes Sara Beatriz , Schaan Violetta K. , Mériaux Sophie B. , Schmitz Stephanie , Bonnemberger Fanny , Schächinger Hartmut , Vögele Claus , Muller Claude P. , Turner Jonathan D. 
Published: August 2019

AbstractEarly life adversity (ELA) has been associated with inflammation and immunosenescence, as well as hyporeactivity of the HPA axis. Because the immune system and the HPA axis are tightly intertwined around the glucocorticoid receptor (GR), we examined peripheral GR functionality in the EpiPath cohort among participants who either had been exposed to ELA (separation from parents and/or institutionalization followed by adoption;n= 40) or had been reared by their biological parents (n= 72).Expression of the strict GR target genesFKBP5andGILZas well as total and1Fand1HGR transcripts were similar between groups. Furthermore, there were no differences in GR sensitivity, examined by the effects of dexamethasone on IL6 production in LPS-stimulated whole blood. Although we did not find differences in methylation at the GR1Fexon or promoter region, we identified a region of the GR1Hpromoter (CpG 1-9) that showed lower methylation levels in ELA.Our results suggest that peripheral GR signaling was unperturbed in our cohort and the observed immune phenotype does not appear to be secondary to an altered GR response to the perturbed HPA axis and glucocorticoid (GC) profile, although we are limited in our measures of GR activity and time points.
Frozen–thawed ampullary cell monolayer improves bovine embryo in vitro development and quality
Authors: Asaadi Anise , Kafi Mojtaba , Atashi Hadi , Azari Mehdi , Hostens Miel 
Published: August 2019

SummaryThe aim of this study was to evaluate the effects of different timing for frozen–thawed bovine ampullary epithelial cell (BAEC) and bovine oviductal epithelial cell (BOEC) co-culture on the development and quality of bovine embryos produced in vitro. Embryo development was assessed by day 8 blastocyst yield, whereas embryo quality was determined using blastocyst differential cell count, cryotolerance and the expression of selected genes related to embryo quality. The results showed that the presence of BAECs during the last 6 h of in vitro maturation (IVM) increased blastocyst yield and survival of the vitrified-warmed blastocysts. In addition, embryos produced in the presence of BAECs during the last 6 h of IVM or in the presence of BOECs during the first 4 days of in vitro culture (IVC) showed a greater number of trophectoderm cells and a greater inner cell mass. In terms of gene expression, IFN-T was downregulated and PLAC8, AQP3 and ATP1A1 were upregulated in the presence of the BAECs during the last 6 h of the IVM and/or in the presence of BOECs during the first 4 days of IVC. In conclusion, co-culturing bovine oocytes with a frozen–thawed ampullary cell monolayer during the last 6 h of maturation increased blastocyst yield and quality.
The effect of repeated controlled ovarian stimulation cycles on the gamete and embryo development
Authors: Paul L.T. , Atilan O. , Tulay P. 
Published: August 2019

SummaryThe aim of this study was to investigate if there is an adverse effect of multiple controlled ovarian stimulation (COS) on the maturity of oocytes (MI and MII), fertilization rate, embryo developmental qualities and clinical pregnancy rates in donation cycles. In total, 65 patients undergoing oocyte donation cycles multiple times were included in this study. Patients were grouped as group A that consisted of donors with ≤2 stimulation cycles while B consisted of donors with ≥3 stimulation cycles; and group C included donors who had ≤15 oocytes, while group D had donors with ≥16 oocytes. Numbers of oocytes obtained, MI and MII oocytes, fertilization, embryo quality and clinical pregnancy outcomes were compared. Significant statistical differences were observed in total number of oocytes obtained, maturity of oocytes (MI and MII), fertilization rate, embryo qualities and clinical pregnancy outcomes of donors in groups A–D. Donors with ≤2 ovarian stimulation cycles had lower numbers of immature oocytes than donors with three or more stimulation cycles. However, donors with ≥3 stimulation cycles had higher numbers of mature oocytes, zygotes, with better day 3 embryo qualities and higher clinical pregnancy rates than donors with ≤2 stimulation cycles. Repeated COS does not seem to have any adverse effect on ovarian response to higher dose of artificial gonadotropin, as quality of oocytes collected and their embryological developmental potential were not affected by the number of successive stimulation cycles. The effect of multiple COS on the health of the oocyte donor needs to be assessed for future purpose.
Low salinity negatively affects early larval development of Nile tilapia, Oreochromis niloticus: insights from skeletal muscle and molecular biomarkers
Authors: Melo Luis Henrique , Martins Yuri Simões , Melo Rafael Magno Costa , Prado Paula Suzanna , Luz Ronald Kennedy , Bazzoli Nilo , Rizzo Elizete 
Published: August 2019

SummaryThe present study evaluated the effects of low salinity on the early larval development of Oreochromis niloticus, specifically histological damage to white muscle, morphology of the yolk-sac surface and trunk area, and molecular expression of apoptosis and cell proliferation biomarkers. Newly hatched larvae were submitted to four salinity treatments for a period of 48 or 72 h, in duplicate: (S0) freshwater, (S2) 2 g l−1, (S4) 4 g l−1, and (S6) 6 g l−1NaCl. Larval development was examined using histology, electron microscopy, enzyme-linked immunosorbent assay (ELISA), and morphometry. At the yolk-sac surface, larvae of S4 and S6 displayed alterations to the apical opening of chloride cells that may be related to osmotic expenditure caused by the increased salinity. Caspase-3 expression did not differ significantly among treatments, however significantly lower proliferating cell nuclear antigen (PCNA) expression (P < 0.05) suggested minor cell proliferation in larvae of S4 and S6 compared with S0 and S2. Furthermore, there was a significant reduction in both trunk area and percentage of normal white muscle fibres (WF) in larvae of S4 and S6. Vacuolated areas and myofibrils concentrated at the cell periphery and found in the white muscle from larvae exposed to saline environments suggested disturbance to muscle development. Oedema and mononuclear infiltrate were also observed in the white muscle of S4 and S6 larvae. Together these results indicated that treatments with 4 and 6 g l−1 NaCl may cause osmoregulation expenditure, morphological alterations to the yolk-sac surface and histological damage to skeletal muscle that negatively affected the early larval development of O. niloticus.
Recovery Trajectories of Child and Family Outcomes Following Online Family Problem-Solving Therapy for Children and Adolescents after Traumatic Brain Injury
Authors: Wade Shari L. , Fisher Allison P. , Kaizar Eloise E. , Yeates Keith O. , Taylor H. Gerry , Zhang Nanhua 
Published: August 2019

AbstractObjectives: We conducted joint analyses from five randomized clinical trials (RCTs) of online family problem-solving therapy (OFPST) for children with traumatic brain injury (TBI) to identify child and parent outcomes most sensitive to OFPST and trajectories of recovery over time. Methods: We examined data from 359 children with complicated mild to severe TBI, aged 5–18, randomized to OFPST or a control condition. Using profile analyses, we examined group differences on parent-reported child (internalizing and externalizing behavior problems, executive function behaviors, social competence) and family outcomes (parental depression, psychological distress, family functioning, parent–child conflict). Results: We found a main effect for measure for both child and family outcomes [F(3, 731) = 7.35, p &lt; .001; F(3, 532) = 4.79, p = .003, respectively], reflecting differing degrees of improvement across measures for both groups. Significant group-by-time interactions indicated that children and families in the OFPST group had fewer problems than controls at both 6 and 18 months post baseline [t(731) = −5.15, p &lt; .001, and t(731) = −3.90, p = .002, respectively, for child outcomes; t(532) = −4.81, p &lt; .001, and t(532) = −3.80, p &lt; .001, respectively, for family outcomes]. Conclusions: The results suggest limited differences in the measures’ responsiveness to treatment while highlighting OFPST’s utility in improving both child behavior problems and parent/family functioning. Group differences were greatest at treatment completion and after extended time post treatment.
Chester Barnard revisited: spontaneous orders and the firm
Authors: Walsh Aidan , Brady Malcolm 
Published: August 2019

AbstractThat governance within the firm is deliberate, conscious and hierarchical, based on authority is considered almost axiomatic. Chester Barnard is cited as an early theorist of this view. In this short article we review Barnard's original theory of authority, his later work and his private correspondence with F. A. Hayek, Michael Polanyi, Bertrand de Jouvenal and others. We show that Barnard focused in his later thinking less on authority and more on ‘responsibility’ and on the spontaneous nature of coordination within the firm, argued for ‘invisible hand’ explanations of coordination within the firm and compared coordination within the firm to market coordination. We use this information to produce novel insights into the work of Chester Barnard and also to demonstrate that his insights into the inner workings of firms is still not completely understood or reflected in the literature on the firm.
CUT ELIMINATION IN HYPERSEQUENT CALCULUS FOR SOME LOGICS OF LINEAR TIME
Authors: INDRZEJCZAK ANDRZEJ 
Published: August 2019

AbstractThis is a sequel article to [10] where a hypersequent calculus (HC) for some temporal logics of linear frames includingKt4.3and its extensions for dense and serial flow of time was investigated in detail. A distinctive feature of this approach is that hypersequents are noncommutative, i.e., they are finite lists of sequents in contrast to other hypersequent approaches using sets or multisets. Such a system in [10] was proved to be cut-free HC formalization of respective logics by means of semantical argument. In this article we present an equivalent variant of this calculus for which a constructive syntactical proof of cut elimination is provided.
THE ELIMINATION OF ATOMIC CUTS AND THE SEMISHORTENING PROPERTY FOR GENTZEN’S SEQUENT CALCULUS WITH EQUALITY
Authors: PARLAMENTO FRANCO , PREVIALE FLAVIO 
Published: August 2019

AbstractWe study various extensions of Gentzen’s sequent calculus obtained by adding rules for equality. One of them is singled out as particularly natural and shown to satisfy full cut elimination, namely, also atomic cuts can be eliminated. Furthermore we tell apart the extensions that satisfy full cut elimination from those that do not and establish a strengthened form of the nonlenghtening property of Lifschitz and Orevkov.
Broadleaf weed control in rain-fed chickpea
Authors: Shahbazi Saeed , Diyanat Marjan , Mahdavi Sareh , Samadi Soheida 
Published: August 2019

AbstractWeeds are among the main limitations on chickpea production in Iran. The efficacy of herbicide treatments including linuron PPI, imazethapyr PPI, PRE, and POST, pendimethalin PPI and POST, bentazon POST, pyridate POST, and oxadiazon POST along with one or two hand weedings were evaluated for weed control and yield response in rain-fed chickpea in Aleshtar, Lorestan, Iran in 2015 and 2016. Wild safflower, threehorn bedstraw, wild mustard, and hoary cress were the predominant weed species in both experimental years. Total weed dry biomass in weedy check plots averaged 187 and 238 g m−2in 2015 and 2016, respectively, and weed density and biomass were reduced in all treatments compared to the weedy check in both years. Treatments composed of pyridate followed by one hand weeding or imazethapyr POST followed by two hand weedings resulted in the lowest weed biomass. The presence of weeds reduced yield by 74% and 66% in the weedy check plots compared to the weed-free control plots in 2015 and 2016, respectively. Application of oxadiazon, bentazon, and imazethapyr PPI, PRE, and POST resulted in lower chickpea yields. All herbicides tested injured chickpea slightly, with pyridate causing the least injury.
Impacts of Hydrological Changes on Nutrient Transport From Diffuse Sources in a Rural River Basin, Western Japan
Authors: Ide Jun'ichiro , Takeda Ikuo , Somura Hiroaki , Mori Yasushi , Sakuno Yuji , Yone Yasumichi , Takahashi Erina 
Published: August 2019

AbstractIncreased frequency of heavy rainfall caused by climate change may affect nutrient transport from forests and agricultural lands into downstream rivers. However, little information is available on how the effects of land cover on nutrient concentrations in the downstream rivers change depending on hydrological conditions. To elucidate this, we investigated the effects of changes in precipitation and river discharge on the relationship between river nutrient concentrations (total nitrogen, total phosphorus, nitrate, and phosphate) and land cover in eight subbasins of the Hii River basin, western Japan. We hypothesized that coniferous forests and agricultural lands including poorly managed ones, which require thinning and fertilizer management, respectively, contribute to increases in nutrient concentrations in downstream rivers during storms. Linear mixed‐effects model analyses based on 18‐year observation data were used for testing the hypothesis. Results revealed that the slopes of the multiple regression analysis between nutrient concentrations and coniferous and broad‐leaved forest area ratios were negative and decreased with increasing daily precipitation. This suggests that forests contributed to the dilution of river nutrient concentrations during storms regardless of whether they were coniferous or broad leaved. In contrast, the slope of regression between nutrient concentrations and agricultural area ratio revealed the opposite trend, indicating that even a small percentage of agricultural area makes a large contribution to increases in nutrient concentrations as precipitation increases. Our results imply that storm runoff in response to rainfall results in an elevated supply of nitrogen and phosphorus attached to arable soils to the river.
Transportation of Diazotroph Community From the Upstream to Downstream of the Kuroshio
Authors: Cheung Shunyan , Suzuki Koji , Xia Xiaomin , Liu Hongbin 
Published: August 2019

AbstractThe Kuroshio is a strong western boundary current in the North Pacific, in which N2 fixation is an important source of new nitrogen. In order to understand the dynamics of diazotrophs in the Kuroshio, we used 454‐pyrosequencing of nifH gene amplicons to unravel and compare the diazotroph communities along the main path of the Kuroshio (23.44° N, 121.99° E–34.3° N, 140.1° E) with its adjacent waters. The diazotroph communities in the geographically distanced stations along the Kuroshio mainstream were highly similar, while those in the Kuroshio adjacent waters were highly varied, indicated that diazotroph communities were actively transported in the Kuroshio. Along the Kuroshio, the UCYN‐A1, UCYN‐C, and Gamma‐A were rather evenly distributed along the Kuroshio, whereas the UCYN‐A2 and Trichodesmium were mainly distributed in the Kuroshio upstream. The diazotroph communities shifted from cyanobacteria dominated in the Kuroshio upstream to proteobacteria (mainly Bradyrhizobium and sulfate‐reducing bacteria) dominated in the downstream. Among all cyanobacterial diazotrophs detected, UCYN‐A1 was the most sustained group in the Kuroshio with >103 gene copies per L and that may explain its extended distribution to higher latitude regions as compared with other cyanobacterial diazotrophs. Considering that the Kuroshio is a hot spot of unicellular cyanobacterial diazotrophs, we have adopted DNA‐directed RNA polymerase subunit beta (rpoC1) gene as a biomarker to further explore their phylogeny. Comparing the data set of nifH and rpoC1 gene fragments, we provided new insights into the phylogeny of the recently defined UCYN‐B2 and poorly understood UCYN‐C groups.
Dripwater and Calcite Geochemistry Variations in a Monitored Bahamas Cave
Authors: Arienzo Monica M. , Mehterian Sevag , Swart Peter K. , Broad Kenneth , Kakuk Brian 
Published: August 2019

AbstractA cave‐monitoring study in Hatchet Bay Cave on the island of Eleuthera, Bahamas, has examined the origins of variations in oxygen and carbon isotopic and minor element composition in cave calcites. Every 3 to 8 months, between 2012 and 2016, temperature, humidity, cave air (δ13CCO2), dripwaters (δ18O and δ2H values, and Ca, Sr, and Mg concentrations), and the chemical composition of precipitating calcite (δ18O and δ13C values, and Ca, Sr, and Mg concentrations) were analyzed in two rooms in the cave. Results from the elemental analyses show that throughout the cave prior calcite precipitation was a driver of the elemental chemistry of the precipitated calcites. In addition, cave calcites show that δ13C and δ18O values were positively correlated with Mg/Ca ratios. The Mg/Ca ratios were also positively correlated with lower calcite precipitation rates. Therefore, water/rock interactions may also influence δ13C and δ18O values and Mg/Ca ratios of the calcite. Differences were observed between the two rooms, with the Main Room of the cave exhibiting increased prior calcite precipitation, more ventilation, lower calcite precipitation rates, and δ18O values, which were farther from equilibrium when compared to the more isolated portion of the cave. These results also validated previous interpretations from Pleistocene stalagmites collected from a nearby Bahamian cave suggesting that a positive covariation between Mg/Ca and δ13C values reflects water/rock interactions.
Evidence of Changes of Seismic Properties in the Entire Crust Beneath Japan After the Mw 9.0, 2011 Tohoku‐oki Earthquake
Authors: Wang Qing‐Yu , Campillo Michel , Brenguier Florent , Lecointre Albanne , Takeda Tetsuya , Hashima Akinori 
Published: August 2019

AbstractStudies of mechanical responses of the Earth crust to large earthquakes can provide us with unique insights into the processes of stress buildup and release. As a complement to geodetic methods that derive crustal strain dynamics from surface observations (e.g., GPS, InSAR), noise‐based seismic velocity monitoring directly probes the mechanical state of the crust, at depth and continuously in time. We investigate the responses of the crust to the Mw 9.0, 2011 Tohoku‐oki earthquake. In addition to the Hi‐net short‐period sensors, we use Hi‐net tiltmeters as long‐period seismometers (8–50 s) to sample the crust below 5 km in depth. The spatial distribution of the strong velocity decreases at short periods appears to be limited to the region of strong ground shaking induced by the 2011 Tohoku‐oki earthquake, while the long‐period velocity changes correlate well with the modeled static strain induced by viscoelastic relaxation and afterslip at depth. Amplitudes of coseismic velocity changes decrease with increasing depth. The temporal evolution of velocity changes in different period bands shows that the maximum drops in the velocity at long periods are delayed in time with respect to the occurrence of the Tohoku‐oki earthquake. The inversion of seismic velocity changes at depth illustrates how S wave velocities evolve down to 40 km at a regional scale after a major earthquake.
Moored Observations of Transport in the Solomon Sea
Authors: Alberty Marion , Sprintall Janet , MacKinnon Jennifer , Germineaud Cyril , Cravatte Sophie , Ganachaud Alexandre 
Published: August 2019

AbstractThe Solomon Sea is a marginal sea in the western Pacific warm pool that contains the South Pacific low latitude western boundary currents. These low latitude western boundary currents chiefly exit the Solomon Sea through three channels (Vitiaz Strait, St. George's Channel, and Solomon Strait) and serve as the primary source water for the Equatorial Undercurrent. Simulations have shown that transport partitioning between the straits determines the water mass structure of the Equatorial Undercurrent, but the relative contributions of transport through each strait have not been observed before. As part of the Southwest Pacific Ocean Circulation and Climate Experiment, an array of moorings was deployed simultaneously in the three outflow channels of the Solomon Sea from July 2012 until March 2014 to resolve transport and water properties in each strait. Above deep isopycnals (σ0 ≤ 27.5), Vitiaz and Solomon Straits account for 54.2% and 36.2% of the mean transport, respectively, with the remaining 9.6% exiting through St. George's Channel. The strongest subinertial transport variability is observed in Solomon Strait and dominates total Solomon Sea transport variability, and a significant fraction of this variability is at intraseasonal time scales. Finally, a previously unobserved deep current at 1,500‐m depth is found to enter the Solomon Sea through Solomon Strait, with a deployment‐mean transport of 4.6 Sv (Sv ≡106 m3/s).
A protective mechanism of probiotic Lactobacillus against hepatic steatosis via reducing host intestinal fatty acid absorption
Authors: Jang Hye Rim , Park Hyun-Jun , Kang Dongwon , Chung Hayung , Nam Myung Hee , Lee Yeonhee , Park Jae-Hak , Lee Hui-Young 
Published: August 2019

AbstractThe gut microbiome has been known to contribute up to ~30% of the energy absorption of the host. Although various beneficial mechanisms of probiotics have been suggested for non-alcoholic fatty liver disease (NAFLD), whether and which probiotics impact the host’s intestinal energy absorption have not yet been quantitatively studied. Here, we suggest a novel mechanism of probiotics against NAFLD, in which Lactobacillus rhamnosus GG, the most common probiotic, shares intestinal fatty acids and prevents the development of diet-induced hepatic steatosis. By using quantitative methods (radioactive tracers and LC–MS) under both in vitro and in vivo conditions, we found that bacteria and hosts competed for fatty acid absorption in the intestine, resulting in decreased weight gain, body fat mass, and hepatic lipid accumulation without differences in calorie intake and excretion in mice fed the probiotic bacteria.