bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integral health assessment of rural population for managerial decision making
Authors: Bayanova N A , Kalininskaya A A , Sulkina F A 
Published: October 2019

Aim. The development of a software product based on the methodology of integral assessment of the health status of the rural population for the rapid assessment of the situation and management decisions.
Methods. The study was conducted in the Orenburg region, which is part of the Volga Federal District. The object of the study was the rural population of the Orenburg region (40.1% of the population of the region) and 35 rural areas with a total number of 799 thousand people. As the initial information for an integral assessment of the health status of the population, the data of the state statistical reporting of the Medical Information and Analytical Center of the Orenburg Region were used. The health status of the rural population was studied in the context of rural areas. Among the indicators (P) for assessing the health status of the rural population the following were used: V the average age of the population of the territory; Zp an indicator of primary incidence; Zo an indicator of the overall incidence; I disability indicator; S mortality rate. The methodology for calculating the integral indicators for assessing the state of health has been tested in all 35 rural areas of the Orenburg region. The analysis made it possible to calculate the number of rural areas that are optimal, favorable, limitedly favorable, unfavorable and especially unfavorable by integral indicators for assessing the health status of the rural population.
Results. Based on the application of our methodology, a software product has been developed that includes a two-dimensional assessment of the results: numerical and color, reflecting the degree of participation of each indicator in the integral assessment. The software product we developed allows us to evaluate public health indicators in a monitoring mode in rural areas. Using a software product makes it possible to assess and determine priorities for making strategic decisions at the level of heads of health authorities and institutions, as well as heads of administration of a subject of the Federation.
Conclusion. The software product for assessing the health status of the population in a rural area may be subject to further expansion and modification of the function, and is also recommended for the presentation of information on the website of administrative territories and the administrative apparatus.
Analysis and prognosis of the epidemic status of the combined HIV/tuberculosis infection in ­correctional facilities
Authors: Ponomarev S B , Vostroknutov M E , Аверьянова E L 
Published: October 2019

Aim. To study the current state of the epidemic status of co-infection of human immunodeficiency virus (HIV) and tuberculosis in penitentiary facilities and to predict its further development.
Methods. The material for the study was the data of departmental forms of medical statistical reporting for the period from 2005 to 2018.
Results. It has been established that the epidemic status of tuberculosis in the penitentiary system institutions is improving, reflected by a decrease in mortality rate over the study period by more than 90%. However, over the study period, the incidence of co-infection of HIV and tuberculosis in penitentiary institutions increased by 3.9 times, and the prevalence by more than 2.5 times. This trend is largely due to the growth of epidemiological indicators of HIV infection. This confirms the established fact that the proportion of HIV-infected people among people followed up with active tuberculosis increased by almost 10 times. Currently, more than one in three newly diagnosed patients with active tuberculosis is infected with HIV. Along with this, the proportion of cases with drug resistance is growing among bacillary patients with active tuberculosis.
Conclusion. The increase in the number of people with co-infection with HIV and tuberculosis and drug-resistant forms of tuberculosis raises doubts on further favorable prognosis for the development of the epidemic situation on tuberculosis both in penitentiary institutions and in the Russian Federation as a whole: an epidemic potential is emerging for an even more complex problem HIV-associated tuberculosis with drug resistance.
New Insight into the Recent Earthquake Activity in North Cambay Basin, Western India: Seismological and Geodetic Perspectives
Authors: Choudhury Pallabee , Chopra Sumer , Kamra Charu , Das Archana 
Published: October 2019

AbstractThe intraplate Gujarat region located at the trijunction of three failed rifts, Kachchh, Narmada, and Cambay, is one of the most seismically active intraplate regions of the world. Among these three, the Cambay basin has been investigated thoroughly for petroleum. However, the basin has not been studied from a seismotectonic perspective. For the past few years, the northern part of the Cambay basin is becoming active with reasonably frequent earthquake occurrences. In the past 10 yr, ∼995 earthquakes have been recorded from the region with a maximum magnitude up to 4.2. Most of the earthquakes are in the magnitude range 1–3. Since 2009, four Global Positioning System (GPS) stations have been in operation in the vicinity of the Cambay basin, and a maximum deformation of 1.8±0.1  mm/yr has been estimated. The GPS‐derived strain rates of ∼0.02–0.03  microstrain/yr are prevalent in the region. An average strain rate of 0.02  microstrain/yr in the region can generate an earthquake of magnitude 6.4. The focal mechanisms of the earthquakes have been mostly normal with strike‐slip component and corroborated by the geodetic strain tensors. Most of the seismicity is clustered in the basement ridges, striking along pre‐existing Precambrian trends that cross the Cambay basin. Complex geodynamics have developed around the northern part of the Cambay rift because of the various movements along several faults, presence of basement ridges, and subsurface plutonic bodies in a failed rift, which are creating stresses and causing earthquakes in this part of the rift. We postulated that the highly heterogeneous subsurface structure beneath the northern part of the Cambay rift is creating additional stress, which is superimposing on the regional stress field substantially, and this mechanism is plausibly facilitating the localized extensional tectonics in the region where compression is expected.
Bazı Makarnalık ve Ekmeklik Buğday Çeşitlerinin Kalite Özelliklerinin Araştırılması
Authors: AYDOĞAN Seydi , ŞAHİN Mehmet , GÖÇMEN AKÇACIK Aysun , DEMİR Berat , HAMZAOĞLU Sümeyra , YAKIŞIR Enes 
Published: October 2019

Bu araştırma bazı
makarnalık buğday ve ekmeklik buğday çeşitlerinin kalite özelliklerinin
karşılaştırılması amacıyla yürütülmüştür. Yedi makarnalık ve yedi ekmeklik buğday çeşidinin sulu
koşullarda tesadüf blokları deneme desenine göre 2 tekerrürlü olarak kalite ve
istatistik analizleri yapılmıştır. Araştırma sonuçlarına göre; ekmeklik buğday
çeşitlerinde ortalama değerlerin değişim aralığı; bin tane ağırlığı 31.10-41.31
g, hektolitre ağırlığı 72.38-78.48 kg, protein oranı % 14.16-16.09, ekmek hacmi
410-570 cm3, farinograf su absorbsiyonu % 62.50-68.20, miksograf gelişme süresi
1.43-2.77 dk., miksograf toplam alanı 358-401 Nm olarak belirlenmiştir.
Makarnalık buğday çeşitlerinde ortalama değerlerin değişim aralıkları; bin tane
ağırlığı 37.05-49.41 g, hektolitre ağırlığı 74.12-78.92 kg, protein oranı %
14.46-16.07, ekmek hacmi 390-475 cm3, farinograf su absorbsiyonu % 67.60-71.10,
miksograf gelişme süresi 2.18-3.42 dk., miksograf toplam alanı 334-412 Nm
olarak bulunmuştur. Ekmeklik buğday çeşitlerinin reolojik hamur özelliklerinin
makarnalık buğday çeşitlerinden daha iyi olduğu belirlenmiştir. Fakat kullanım
amacına göre hammadde kalite talebinin değişebileceği göz önünde bulundurularak
üretim yapılacak çeşit seçimine dikkat edilmelidir.
Effect of Remineralizing Agents on Tooth Color After Home Bleaching
Authors: Malekipour Mohammadreza , Norouzi Zahra , Shahlaei Sahar 
Published: October 2019

Objectives: The purpose was to investigate the effect of casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) paste, Remin Pro paste, and 0.05% sodium fluoride (NaF) mouthwash on teeth discoloration after home bleaching.
Materials and Methods: In this in-vitro study, 48 intact and unstained human incisors were divided into four groups (n=12): control (Group 1), CPP-ACPF paste (Group 2), Remin Pro paste (Group 3), and 0.05% NaF mouthwash (Group 4). The specimens were bleached using 20% carbamide peroxide gel for 21 days and were subjected to pH cycling and surface treatment with remineralizing agents for one month. The color of the specimens was determined according to the CIELAB color space at baseline, after bleaching, and after surface treatment. Data were analyzed using one-way analysis of variance (ANOVA), post-hoc least significant difference (LSD) test, and one-sample t-test (P=0.05).
Results: ANOVA showed a significant difference in the mean ΔE of the four groups after surface treatment (P<0.05). Post-hoc LSD test showed a significant difference between the mean ΔE of the control group and those of the treatment groups (P<0.05) with no significant difference between the treatment groups, except for Remin Pro. The mean ΔE and ΔL of the Remin Pro group showed less change than those of the CPP-ACPF and NaF groups, indicating that Remin Pro has the lowest potential for post-bleaching tooth discoloration.
Conclusion: CPP-ACPF paste, Remin Pro paste, and 0.05% NaF mouthwash cause noticeable teeth discoloration immediately after bleaching. Remin Pro has less effect on tooth color than the other two products.
Effect of aqueous extract of olive leaves on some biochemical changes induced by carbon tetrachloride in male rats
Authors: Ashour Saleh E. , Mohamed Naglaa E. 
Published: October 2019

Olive tree leaves have been widely used in traditional remedies in European and Mediterranean countries and in the human diet as extracts, herbal teas, and powder, which contain several potential bioactive compounds that may have antihypertensive, antiatherogenic, anti-inflammatory, hypoglycemic, hypocholesterolemic, antidiabetic and antioxidant activities. The present study was carried out to evaluate the role of olive leaves extracts (OLE) in ameliorating the metabolic changes in rats treated with carbon tetrachloride (CCl4). Forty-eight male rats were classified into six groups; the first group was the control which received 1 ml distilled water, the second group was treated daily with oral dose of cold OLE (1 ml/kg) for one month, the third group was treated daily with oral dose of boiled OLE (1 ml/kg) for one month, the fourth group was treated daily with oral dose of CCl4 (1 ml/kg) for one month, the fifth group was treated with both cold OLE and CCl4 (1 ml/kg for each) for one month and the sixth group was treated with both boiled OLE and CCl4 (1 ml/kg for each) for one month. Serum levels of thiobarbituric acid reactive substance (TBARS), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma-glutamyl transferase (GGT), lactate dehydrogenase (LDH), urea, creatinine, insulin and glutathione (GSH), catalase (CAT), albumin, total protein, free triiodothyronine (FT3) , free thyroxin (FT4) were measured in serum. Histological examination of hepatic tissue was examined. The results showed that administration of CCl4 to rats induced significant increase (P<0.05) in serum levels of thiobarbituric acid reactive substance (TBARS), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), gamma- glutamyl transferase (GGT), lactate dehydrogenase (LDH), urea, creatinine, insulin and significant decrease (P<0.05) in glutathione (GSH), catalase (CAT), albumin, total protein, free triiodothyronine (FT3) and free thyroxin (FT4). The histological examination of hepatic tissue showed some degenerative changes while significant improvement in biochemical and histological changes was observed either in CCl4 + cold OLE or CCl4 + boiled OLE groups. It could be concluded that the protective effect of olive leaves extract either cold or boiling may be attributed to its antioxidant properties. The obtained results indicated that both cold and boiled olive leaves extract has potent effect to restore the antioxidant status, hepato-renal function, insulin and thyroid hormones near to the control levels.
Penerapan Metode Simpang Tegar untuk Meningkatkan Kemampuan Guru dalam Penulisan PTK dan Artikel Ilmiah
Authors: Widana I Wayan , Suarta I Made , Citrawan I Wayan 
Published: October 2019

The ability of SMAN 1 Selemadeg and SMAN 1 Kerambitan, Tabanan Regency, Bali Province teachers, in writing Classrom Action Research (CAR) reports and articles is very low. This problem has an impact on the delay of the promotion of teachers for many years, because one of the requirements is not fulfilled in the element of scientific papers. Community service aims to improve the ability of teachers in writing CAR and articles. To achieve these objectives, the Simpang Tegar method is implemented. Data on teacher understanding of the basic concepts of CAR and articles were collected using the test method. While the data on the skills of teachers writing CAR and articles are collected using observation and check-list of tasks given during mentoring. The results obtained are as follows: (1) teacher's understanding of the basic concepts of CAR and scientific articles increased from an average of 57.34 during the pre-test to 73.93 during the post-test; (2) teacher's skills of writing CAR reports and articles increased from an average of 45.41 before mentoring, to 68.58 after mentoring
The effects of food simulating liquids on surface roughness, hardness, and solubility of bulk fill composites
Authors: Cabadağ Özge Gizem , GÖNÜLOL NİHAN 
Published: October 2019

Abstract
Abstract
Background: The aim of this study was to compare the effects of food simulating liquids (FSLs) on the surface roughness, surface hardness and solubility of bulk fill composites.
Methods: Two-hundred samples were prepared from four high viscosity bulk fill composites (SonicFill TM , Tetric® EvoCeram Bulk Fill, Beautifil-Bulk Restorative, Filtek TM Bulk Fill Posterior Restorative) and a microhybrid composite (Filtek TM Z250). After the initial weights of the samples were recorded (m 1 ), surface roughness measurements were evaluated with a profilometer. The samples were stored in 4 different FSLs for 7 days, then the second surface roughness values were recorded. Then the samples were stored in a desiccator to reach the constant mass and the values were recorded as m 2 . The solubility levels were calculated according to the ISO 4049: 2009 specification. The surface hardness values of the samples were determined by using the Vickers microhardness measuring device. Twenty specimens from each group were evaluated in terms of surface morphology with scanning electron microscope (SEM).
Results: Beautifil Bulk Restorative was the most affected group in terms of surface roughness after storage in FSLs and citric acid caused the highest values in this group (p<0,005). Beautifil Bulk Restorative and Filtek Z250 groups showed the highest surface hardness values, while the Tetric EvoCeram group had the lowest. The highest solubility values were detected in Beautifil Bulk Restorative group, and citric acid and ethanol caused the highest solubility values on all the tested composites.
Conclusions: Beautifil Bulk Restorative group showed the highest surface roughness and solubility values among the tested groups, while the same group showed the highest surface hardness.
Key Words: Bulk fill composites, food simulating liquids, solubility, surface hardness, surface roughness.
Safety and efficacy of different administration order on paradoxical reactions following midazolam in children: a randomised, controlled trial
Authors: zhu change , Zhang Saiji , Wei Rong 
Published: October 2019

Abstract
Study Objective Midazolam is commonly used for Anesthesia induction. However, the paradoxical reactions increase risk of self-injury and bring pressure on anesthesiologist. Although various drugs have been showed effective, but the potential adverse effects limit the application. We compared safety and efficacy of different administration order on the occurrence of paradoxical reactions in children.Design Prospective, randomized, double-blinded study.Setting Operating room of a university-affiliated hospital.Patients 1306 ASA physical status I pediatric patients, aged 6 months to 12 years, scheduled for general anesthesia.Interventions Patients were divided into three groups. In the fentanyl group, patients were given fentanyl followed by midazolam at induction; In the midazolam group patients received midazolam followed by fentanyl at induction; In the blank group, patients were given saline followed by fentanyl at induction. Propofol was administrated 2.5 mg/kg intravenously (IV).Measurements Onset of paradoxical reactions and BIS values were observed and recorded.Main Results Preferentially and slowly injecting fentanyl could decrease the incidence of paradoxical reaction (p<0.05). Children displaying paradoxical reactions were mostly aged 8 months-2 years old (p = 0.001). Bispectralindex values increased significantly when paradoxical reactions burst out (p< 0.05). There were no significant differences in terms of side-effects.Conclusion Changing the administration order was safe and effective to decrease the incidence of paradoxical reactions.
Potent antibacterial activity of Dihydydropyrimidine-1,3,5-triazines via inhibition of DNA gyrase and antifungal activity with favourable metabolic profile
Authors: Masih Anup , Shrivastava Jitendra Kumar , Bhat Hans Raj , Singh Udaya Pratap 
Published: October 2019

Abstract
The compounds were tested against panel of three Gram-positive, viz. Staphylococcus aureus, Bacillus subtilis, Bacillus cereus and three Gram-negative bacterial strains viz. Pseudomonas aeruginosa, Escherichia coli, and Proteus vulgaris for determination of their antibacterial efficacy using cefixime as a standard drug. The antibiofilm activities of the compounds were determined against Staphylococcus aureus, and Bacillus subtilis. The most potent compounds 7l amd 7m found bacteriostatic in time kill assay via inhibition of DNA Gyrase enzyme. The metabolic liability of compound 7m was determined using RS-Predictor and MetaPrint 2D React. The antifungal activity against human fungal pathogens was also estimated, where these compounds showed considerable activity in comparison to standard. The in vivo antibacterial activity of compound 7m was also determined using S. aureus induced murine infection model.
Efficacy of continuous ascorbate infusion on lymphopenia and neutrophil counts in the supportive care of cancer patients
Authors: Mikirova Nina 
Published: October 2019

Abstract
Abnormal blood counts and, in particular, lymphopenia commonly occur in cancer patients and predict poor prognosis. In this study data from a previous Phase 1 clinical trial of continuous vitamin C infusions were analyzed. The trends in the absolute lymphocyte counts (ALC), absolute neutrophil counts (ANC) and neutrophil to lymphocyte ratio (NLR) were evaluated. In addition, pharmacokinetic data on IVC in patients who were treated by continuous infusion were determined for different dosages.

During continuous infusion treatment, data for all patients, who completed 6-8 weeks of the treatment, demonstrated improvement of lymphocyte counts in patients with lymphopenia. On average the percentage of improvement in ALC was 22% for ALC <1300 /µl and 69% for ALC <1000 cells/µl. Our data also indicate that lower doses (less than 20 g/70 kg) were more favorable for the improvement of ALC. In addition, the data suggest a normalizing effect of continuous infusions of ANC levels and changes in NLR. In summary, the present analysis demonstrated the normalizing effect of continuous IVC on lymphopenia, ANC and NLR.
A school intervention within an oral health promotion program in New Caledonia: Evaluation with a pragmatic approach
Authors: Pichot Hélène , Pereira Bruno , Magnat Elodie , Tubert-jeannin stephanie 
Published: October 2019

Abstract
Background : The objective of this observational survey was to evaluate after one year, a dental sealants intervention conducted in New Caledonia, within an health promotion program. A greater or at least equivalent impact of the intervention was expected in socially deprived sectors with highest health needs. Methods : The study population was the schoolchildren, aged 6 years in 2016, who benefited from the dental sealant program (n=2532). The study sample was randomly selected in 2017 from that population (n=550). The children's dental status was evaluated at school and compared with that recorded in 2016 during the sealant intervention allowing the calculation of the retention rates and one year carious increment (∆DT 1rst molars ). Socio-demographic variables (gender, region, public/private school) and conditions of sealants placement (school/dental office, presence of a dental assistant) were recorded. The carious increment was explained using a mixed multiple random-effects regression. A mediation analysis was conducted to assess the respective contributions of the retention rates and the region on caries increment. Results : The participation rate was very high (89%) and 80% of the dental sealants were present after one year; 30% totally and 60% partially present. Caries increment varied depending on the sealant retention rate as well as on the region (North, South, Islands). The mediation analysis showed that living in a deprived area (The Islands) was a strong determinant for high caries increment particularly when the retention rates were low. Conclusions : This survey showed a high participation rate and good effectiveness as measured with the one-year retention rates, for a sealant intervention integrated in a large health promotion program. Nevertheless, the program was not effective enough to balance the influence of other health determinants in socially deprived sectors characterized by high dental needs.
Referring crown-to-root ratio and root surface area to assess periodontitis severity and prognosis
Authors: Hong Hsiang-Hsi , Liang Chao-Hua , Chang Chung-Chieh , Peng Ying-Chin , Liu Heng-Liang 
Published: October 2019

Abstract
Background: Whether the linear crown-to-root ratio (CRR) decided by 3D and 2D clinical attachment loss (CAL) can be applied to evaluate the periodontitis severity and tooth prognosis was rarely examined. Materials: Sixty-six mandibular and maxillary single-rooted human premolars were surveyed by micro-computed tomography. CRRs at the levels of defined mild, moderate and severe periodontitis severity were analyzed. Statistical significance was confirmed by t -testes. Results: Along with the definitions, both the findings of coronal 25% root surface area (RSA) with CRR=1:1 corresponded to ≤3.0 mm linear radiographic bone loss (L-RBL) and 20% RSA with CRR=4:5 at L-RBL=1.6‒1.9 mm signified ≤15% L-RBL were categorized as mild periodontitis. Similarly, the results of coronal RSA≤52% with CRR≤3:2 at L-RBL≤5.0 mm and RSA=40% with CRR=5:4 at 4.0 mm L-RBL denoted 30% L-RBL were characterized moderate periodontitis. Additionally, relying on whether a 1.0mm connective tissue attachment (CTA) was included, CRR=1:1 at 25% L-RBL or CRR=4:3 at 35% L-RBL corresponded to a 25% clinical attachment loss (CAL), which could be used to distinguish a fair prognosis from a good prognosis. Either the level with 50% L-RBL at CRR=2:1, or the level with 50% CAL and 60% L-RBL at CRR=5:2 could be applied to differentiate a poor prognosis from a questionable prognosis. Conclusions: The periodontitis severity and tooth prognosis defined by 2015 academic classification could be evaluated according to a range of corresponding RSAs and CRRs. The length and morphology of the tapered roots and decreasing CTA enclosure partially explained the findings.