bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ties that Bind: The Link between Functions of Public Sector Manager in Tanzania and Luther Gulick’s Notes on The Theory of Organization
Authors: Marijani Ramadhani 
Published: September 2018

Abstract
This paper reflects Gulick’s notes on the theory of organization in the context of Public Sector Manager’s work milieu in Tanzania. Using the Performance Improvement Model (PIM) as the proxy the paper instantiates the POSDCORB by drawing the parallels between the POSDCORB mnemonic and PIM and therefore corroborates Gulick’s summation. We argue that in order to apply the classic theory of organization in today’s public administration an attempt should be made to view organization theory from a design perspective. The paper recommends that more research should be done to instantiate POSDCORB and contributes to the corpus knowledge of public administration discipline.
The perception and attitude of the resident and tourists regarding the local public administration and the tourism phenomenon
Authors: Frînculeasa Mădălina Nicoleta , Chiţescu Răzvan Ion 
Published: September 2018

Abstract
The dynamism of the tourism phenomenon in relation to interconditioning with the local administrative environment, through the generated effects, can constitute an element of favorability of the socio-economic development of community. At the same time, tourism development also generates many problems for host communities. Thus, the policy developed by the local public administration regarding the tourism phenomenon regards the creation and maintenance of a competitive space for the involved actors (residents, tourists, institutions of public and private administration) in order to manage and supply profitable tourist products in a socio-economic context sustainable. Analyzing the perception and attitude of the residents of Moroieni, Dâmbovița, and the tourists present in this area, the paper presents the results of a sociological research which establishes the role and involvement of the local public administration in the tourism phenomenon.
Influence of Entrance Exams Results on Foreign Students in Economics Studies at University of Economics, Prague
Authors: Maryska Milos , Doucek Petr 
Published: September 2018

Abstract

Background and purpose: The purpose of the article is to analyse results of entrance exams and of regularly exams for foreign students in the Czech language undergraduate study programs at four faculties of University of Economics, Prague (UEP) with the intention to investigate the dependency between the results of Entrance exams from English and mathematics and (1) results of regularly exams during the study and between (2) completion rate of the study.

Design/Methodology/Approach: We have analysed 4.381 records for applicants from foreign countries who applied for studies between years 2009 and 2015. We used standard statistics methods and the method of logistic regression in the form of logit model.

Results: We identified weak statistical correlation between entrance exam results from mathematics and results of regular exams. The correlation coefficient varies between 0.078 – 0.283 for investigated faculties of UEP. The same indicator for English language exams presents better values and it varies between 0.218 – 0.312. If an entrance exam result is higher by one point, the probability of successful completion of studies is multiplied by values between 1.017 - 1.042 for individual faculty per one additional point.

Conclusion: The results of the research in mathematics and English language show that excellent results in entrance exam cannot not guarantee successful regularly exams. Conclusion for the probability of completing studies is that the acceptable level of points for admission foreign students is between 150 and 170 points, depending on the faculty.
Performance Indicators of Management Buyouts Using the Analytic Hierarchy Process Method
Authors: Grah Petra , Čančer Vesna , Bratina Borut 
Published: September 2018

Abstract

Background and Purpose: In Slovenia, few management buyout (MBO) studies have been carried out. The focus was mostly on the motives for acquisition of companies and the success rate of the acquisitions. This paper aims to analyse the indicators which suggest an impending bankruptcy or financial restructuring of companies and explore how these indicators are different for successful and unsuccessful MBOs.

Methodology: In the survey, we included 23 selected MBOs in Slovenia between 2005 and 2008, using the following financial and non-financial indicators: profitability, performance, solvency and liquidity, using the analytic hierarchy process method. The key aim of the survey was to use financial and non-financial indicators to study if target companies where bankruptcy or financial restructuring has not yet been initiated prevalently have higher aggregate values compared to those in which bankruptcy or financial restructuring procedures have already begun. Thus, we used the selected indicators to demonstrate one of the possible methods to predict the success of a particular MBO.

Results: We found that in most examples of unsuccessful MBOs, target companies have poorer results in terms of performance, solvency and liquidity, when compared to successful MBOs. Based on the selected areas, we divided the results into four quarters. We found that most target companies where MBOs had been unsuccessful are ranked in a lower quarter than most of the target companies where the MBOs had been successful.

Conclusion: The papers main contribution is the finding that the selected financial and non-financial indicators differ in cases of successful and unsuccessful MBOs. This knowledge helps us to find ways of avoiding these situations in the future.
Analysis of regional heterogeneities of the blood-brain barrier in humans and mice
Authors: Ádám Nyúl-Tóth , Ádám Mészáros , Fanni Győri , Imola Wilhelm , Krizbai István A. 
Published: September 2018

Abstract
Proper functioning of the nervous system is largely dependent on the precise regulation of the neuronal environment. By shielding the central nervous system (CNS) from potentially harmful substances, the blood-brain barrier (BBB) has an indispensable role in this process. The BBB is a specialized system of endothelial cells lining brain microvessels, which – supported by pericytes and glial cells – form a selective barrier between the blood and the neural tissue. Under abnormal conditions, permeability of the BBB may increase, which may either trigger or aggravate the disease. Since CNS disorders – at least in their initial phase – usually do not involve the whole brain and spinal cord, but are localized to a certain region, our aim was to understand whether the BBB is regionally heterogeneous at the molecular level. By using bioinformatics tools, we analyzed expression levels of genes specific to cerebral endothelial cells, pericytes or astrocytes in different brain territories. Our results revealed regional heterogeneities in the expression of BBB-associated genes in both human and mouse. Expression pattern of efflux transporters – which have a major role in blocking passage of therapeutic agents through the BBB – proved to be diverse both among brain regions and between mouse and human. Our results indicate that: (1) in silico database analyses are suitable for group-based studies on gene functions, overcoming the limitations of single-gene analyses; (2) high-throughput tests should always be validated using other methods; (3) when using animal models, inter-species differences have to be always considered; (4) when comparing different brain regions, the BBB is heterogeneous at the molecular level, and this might have clinical significance.
Participatory Mapping in Community Participation – Case Study of Jeseník, Czech Republic
Authors: Pánek Jiří 
Published: September 2018

Abstract
Community participation has entered the 21st century and the era of e-participation, e-government and e-planning. With the opportunity to use Public Participation Support Systems, Computer-Aided Web Interviews and crowdsourcing mapping platforms, citizens are equipped with the tools to have their voices heard. This paper presents a case study of the deployment of such an online mapping platform in Jeseník, Czech Republic. In total, 533 respondents took part in the online mapping survey, which included six spatial questions. Respondents marked 4,714 points and added 1,538 comments to these points. The main aim of the research was to find whether there were any significant differences in the answers from selected groups (age, gender, home location) of respondents. The results show largest differences in answers of various (below 20 and above 20 year) age groups. Nevertheless further statistical examination would be needed to confirm the visual comparison.
Analisis Rasio Keuangan Untuk Memprediksi Financial Distress Pada Perusahaan Manufaktur Yang Terdaftar Di Bursa Efek Indonesia 2014-2016
Authors: Maulida Indira Shofia , Moehaditoyo Srie Hartutie , Nugroho Mulyanto 
Published: September 2018

Tujuan dari penelitian ini adalah untuk menganalisa pengaruh rasio likuiditas, solvabilitas, profitabilitas, aktivitas, pertumbuhan terhadap terjadinya financil distress pada perusahaan manufaktur periode 2014-2016. Teknik analisis datanya meggunakan PLS (Partial Least Square) yang bertujuan untuk memprediksi besar pengaruh Current Ratio, Debt to Asset Ratio (DAR), Debt to Equity Ratio, ROA, ROE, NPM, Receviable Turn Over, Growth Ratio terhadap financial distress yang dilihat dari nilai EPS bernilai negatif 2 tahun berturut-turut. Hasil dari uji hipotesis bahwa rasio Likuiditas menunjukkan positive tidak signifikan terhadap terjadinya financial distress sedangkan rasio solvabilitas dan rasio pertumbuhan menunjukan positive signifikan kemudian rasio aktivitas dan profitabilitas menunjukkan bahwa negative signifikan terhadap financial distress. Dilihat dari nilai R-Square kontribusi pengaruh likuiditas, solvabilitas, profitabilitas, aktivitas, pertumbuhan terhadap financial distress sebesar 48,9 %. Kata Kunci : Rasio Keuangan, Financial Distress, Laporan Keuangan
Comparison of treatment results between 3- and 2-stage Gamma Knife radiosurgery for large brain metastases: a retrospective multi-institutional study
Authors: Serizawa Toru , Higuchi Yoshinori , Yamamoto Masaaki , Matsunaga Shigeo , Nagano Osamu , Sato Yasunori , Aoyagi Kyoko , Yomo Shoji , Koiso Takao , Hasegawa Toshinori , Nakazaki Kiyoshi , Moriki Akihito , Kondoh Takeshi , Nagatomo Yasushi , Okamoto Hisayo , Kohda Yukihiko , Kawai Hideya , Shidoh Satoka , Shibazaki Toru , Onoue Shinji , Kenai Hiroyuki , Inoue Akira , Mori Hisae 
Published: September 2018

OBJECTIVEIn order to obtain better local tumor control for large (i.e., > 3 cm in diameter or > 10 cm3 in volume) brain metastases (BMs), 3-stage and 2-stage Gamma Knife surgery (GKS) procedures, rather than a palliative dose of stereotactic radiosurgery, have been proposed. Here, authors conducted a retrospective multi-institutional study to compare treatment results between 3-stage and 2-stage GKS for large BMs.METHODSThis retrospective multi-institutional study involved 335 patients from 19 Gamma Knife facilities in Japan. Major inclusion criteria were 1) newly diagnosed BMs, 2) largest tumor volume of 10.0–33.5 cm3, 3) cumulative intracranial tumor volume ≤ 50 cm3, 4) no leptomeningeal dissemination, 5) no more than 10 tumors, and 6) Karnofsky Performance Status 70% or better. Prescription doses were restricted to between 9.0 and 11.0 Gy in 3-stage GKS and between 11.8 and 14.2 Gy in 2-stage GKS. The total treatment interval had to be within 6 weeks, with at least 12 days between procedures. There were 114 cases in the 3-stage group and 221 in the 2-stage group. Because of the disproportion in patient numbers and the pre-GKS clinical factors between these two GKS groups, a case-matched study was performed using the propensity score matching method. Ultimately, 212 patients (106 from each group) were selected for the case-matched study. Overall survival, tumor progression, neurological death, and radiation-related adverse events were analyzed.RESULTSIn the case-matched cohort, post-GKS median survival time tended to be longer in the 3-stage group (15.9 months) than in the 2-stage group (11.7 months), but the difference was not statistically significant (p = 0.65). The cumulative incidences of tumor progression (21.6% vs 16.7% at 1 year, p = 0.31), neurological death (5.1% vs 6.0% at 1 year, p = 0.58), or serious radiation-related adverse events (3.0% vs 4.0% at 1 year, p = 0.49) did not differ significantly.CONCLUSIONSThis retrospective multi-institutional study showed no differences between 3-stage and 2-stage GKS in terms of overall survival, tumor progression, neurological death, and radiation-related adverse events. Both 3-stage and 2-stage GKS performed according to the aforementioned protocols are good treatment options in selected patients with large BMs.
Thoracogenic spinal deformity: a rare cause of early-onset scoliosis
Authors: Eby Sarah F. , Hilaire Tricia St. , Glotzbecker Michael , Smith John , White Klane K. , Larson A. Noelle , _ _ 
Published: September 2018

OBJECTIVESurgery for severe congenital defects, such as congenital diaphragmatic hernia, congenital heart defects, and tracheoesophageal disorders, are life-saving treatments for many infants. However, the incidence of scoliosis following thoracoabdominal surgery has been reported to range from 8% to 50%. Little is known about severe scoliosis that occurs after chest wall procedures in infants. The authors sought to determine the prevalence of thoracogenic scoliosis, disease severity, and need for scoliosis surgery in patients who underwent chest wall procedures in early childhood.METHODSA multicenter database of patients with early-onset scoliosis was queried to identify patients with a history of thoracogenic or acquired iatrogenic scoliosis. Patients with significant congenital spine deformities were excluded. Forty-one patients (1.6%) were noted to have thoracogenic scoliosis. Of these patients, 14 patients were observed; 10 received casts and/or braces; and 17 underwent treatment with rib-based distraction rods, Shilla procedures, or spine-based growing rod devices. Radiographs, complications, and patient characteristics were reviewed.RESULTSThe mean age at scoliosis diagnosis for the 41 patients was 6.0 years. The mean time to follow-up was 2.9 years (4.5 years in the 17 surgical patients). The mean preoperative coronal Cobb angle in the surgical group was 65° and improved to 47° postoperatively (p = 0.01). The mean Cobb angle for the nonoperative group was 31° initially and 32° at follow-up (p = 0.44). Among the 17 patients undergoing surgery for scoliosis, there were 13 complications in 7 patients, including a brachial plexus palsy following rib-based distraction rod placement. This resolved with revision of the rib hooks. There were no known complications in the nonoperative cohort.CONCLUSIONSSevere scoliosis can develop after thoracoabdominal surgeries during infancy. Further work is needed to understand the pathogenesis of scoliosis in this population so as to implement measures for prevention and early diagnosis and to guide appropriate treatment.
Kandungan Protein dan Kalsium Pada Biskuit Formula Tempe dengan Penambahan Tepung Daun Kelor (Moringa oleifera) Sebagai Makanan Pendamping ASI (MP-ASI)
Authors: Suhartini Tri , Zakaria Zakaria , Pakhri Asmarudin , Mustamin Mustamin 
Published: September 2018

The results of the research on tempe biscuit with the substitution of moringa flour as MP-ASI did not reveal the content of protein and calcium which is a nutrient Which is important to know as fast food. This study aims to determine the content of protein and calcium in tempe biscuit formula with kelor leaf flour substitution.This research uses laboratory. Samples analyzed were 2 samples with no substitution of 0% Moringa flour (control) and samples with Moringa flour substitution 9% (13.5 g) based on consumer acceptance. Aanalysis of proteins by khjedal method and mineral by atomic analysis spektrofothometer (AAS). The results showed that the content of protein and calcium biscuit of tempe formula with the substitution of maize flour 9% (13.5 g) respectively by 14.9% and 38.3 mg, Greater than non-substitution of maize leaf powder respectively 12.6% and 21.4 g. It was concluded that the content of protein and calcium biscuit with the substitution of moringa flour is higher than that without the substitution of moringa flour. Further research on the formulation of complementari of food for breast milk is required to balance the nutritional value in accordance with the needs of infants 6-24 months. Keywords : Biscuits, Protein Content, Calcium Conten
On the Kinematic Signature of the Galactic Warp As Revealed By the LAMOST-TGAS Data
Authors: Huang Y. , Schönrich R. , Liu X.-W. , Chen B.-Q. , Zhang H.-W. , Yuan H.-B. , Xiang M.-S. , Wang C. , Tian Z.-J. 
Published: September 2018

Abstract
Using a sample of about 123,000 stars with accurate 3D velocity measurements from the LAMOST-TGAS data, we confirm the kinematic signature of the Galactic warp recently found by Schönrich & Dehnen. The data reveal a clear trend of increasing mean vertical velocity

as a function of absolute vertical angular momentum L

z
and azimuthal velocity V

ϕ
for guiding center radius R

g
between 6.0 and 10.5 kpc. The trend is consistent with a large-scale Galactic warp. Similar to Schönrich & Dehnen, we also find a wave-like pattern of

versus L

z
with an amplitude of ∼0.9 km s−1 on a scale of ∼2.0 kpc, which could arise from bending waves or a winding warp. Finally, we confirm a prominent, localized peak in

near L

z
∼ 2150 kpc km s−1 (corresponding to R

g
∼ 9 kpc and V

ϕ
∼ 255 km s−1). The additional line-of-sight velocity information from LAMOST reveals that stars in this feature have a large, inward radial velocity of V

R
∼ −13.33 ± 0.59 km s−1 and a small radial velocity dispersion of σ

R
∼ 25.27 ± 0.89 km s−1, suggesting that a stellar stream gives rise to this feature.
Two-temperature GRRMHD Simulations of M87
Authors: Ryan Benjamin R. , Ressler Sean M. , Dolence Joshua C. , Gammie Charles , Quataert Eliot 
Published: September 2018

Abstract
We present axisymmetric two-temperature general relativistic radiation magnetohydrodynamic simulations of the inner region of the accretion flow onto the supermassive black hole M87. We address uncertainties from previous modeling efforts through inclusion of models for (1) self-consistent dissipative and Coulomb electron heating (2) radiation transport (3) frequency-dependent synchrotron emission, self-absorption, and Compton scattering. We adopt a distance D = 16.7 Mpc, an observer angle θ = 20°, and consider black hole masses

and spins a
⋆ = (0.5, 0.9375) in a four-simulation suite. For each (M, a
⋆), we identify the accretion rate that recovers the 230 GHz flux from very long baseline interferometry measurements. We report on disk thermodynamics at these accretion rates (

). The disk remains geometrically thick; cooling does not lead to a thin disk component. While electron heating is dominated by Coulomb rather than dissipation for r ≳ 10GM/c
2, the accretion disk remains two-temperature. Radiative cooling of electrons is not negligible, especially for r ≲ 10GM/c
2. The Compton y parameter is of order unity. We then compare derived and observed or inferred spectra, millimeter images, and jet powers. Simulations with M/M
⊙ = 3.3 × 109 are in conflict with observations. These simulations produce millimeter images that are too small, while the low-spin simulation also overproduces X-rays. For

, both simulations agree with constraints on radio/IR/X-ray fluxes and millimeter image sizes. Simulation jet power is a factor 102–103 below inferred values, a possible consequence of the modest net magnetic flux in our models.
Haptoglobin Is a Divergent MASP Family Member That Neofunctionalized To Recycle Hemoglobin via CD163 in Mammals
Authors: Redmond Anthony K. , Ohta Yuko , Criscitiello Michael F. , Macqueen Daniel J. , Flajnik Martin F. , Dooley Helen 
Published: September 2018

Abstract
In mammals, haptoglobin (Hp) is an acute-phase plasma protein that binds with high affinity to hemoglobin (Hb) released by intravascular hemolysis. The resultant Hp–Hb complexes are bound and cleared by the scavenger receptor CD163, limiting Hb-induced oxidative damage. In this study, we show that Hp is a divergent member of the complement-initiating MASP family of proteins, which emerged in the ancestor of jawed vertebrates. We demonstrate that Hp has been independently lost from multiple vertebrate lineages, that characterized Hb-interacting residues of mammals are poorly conserved in nonmammalian species maintaining Hp, and that the extended loop 3 region of Hp, which mediates CD163 binding, is present only in mammals. We show that the Hb-binding ability of cartilaginous fish (nurse shark, Ginglymostoma cirratum; small-spotted catshark, Scyliorhinus canicula; and thornback ray, Raja clavata) and teleost fish (rainbow trout, Oncorhynchus mykiss) Hp is species specific, and where binding does occur it is likely mediated through a different structural mechanism to mammalian Hp. The continued, high-level expression of Hp in cartilaginous fishes in which Hb binding is not evident signals that Hp has (an)other, yet unstudied, role(s) in these species. Previous work indicates that mammalian Hp also has secondary, immunomodulatory functions that are independent of Hb binding; our work suggests these may be remnants of evolutionary more ancient functions, retained after Hb removal became the primary role of Hp in mammals.
Gravity waves excited during a minor sudden stratospheric warming
Authors: Dörnbrack Andreas , Gisinger Sonja , Kaifler Natalie , Portele Tanja Christina , Bramberger Martina , Rapp Markus , Gerding Michael , Faber Jens , Žagar Nedjeljka , Jelić Damjan 
Published: September 2018

Abstract. An exceptionally deep upper-air sounding launched from Kiruna
airport (67.82∘ N, 20.33∘ E) on 30 January 2016 stimulated
the current investigation of internal gravity waves excited during a minor
sudden stratospheric warming (SSW) in the Arctic winter 2015/16. The analysis
of the radiosonde profile revealed large kinetic and potential energies in
the upper stratosphere without any simultaneous enhancement of upper
tropospheric and lower stratospheric values. Upward-propagating
inertia-gravity waves in the upper stratosphere and downward-propagating
modes in the lower stratosphere indicated a region of gravity wave generation
in the stratosphere. Two-dimensional wavelet analysis was applied to vertical
time series of temperature fluctuations in order to determine the vertical
propagation direction of the stratospheric gravity waves in 1-hourly
high-resolution meteorological analyses and short-term forecasts. The
separation of upward- and downward-propagating waves provided further evidence
for a stratospheric source of gravity waves. The scale-dependent
decomposition of the flow into a balanced component and inertia-gravity waves
showed that coherent wave packets preferentially occurred at the inner edge
of the Arctic polar vortex where a sub-vortex formed during the minor SSW.