bluuebunny/crossref_metadata_2025_split huggingface dataset:
MORPHOGISTOSCHEMICAL CHARACTERISTIC OF THE IMPLANT FROM POLYLACTIC ACID
Authors: Mogilnaya G. M. , Fomicheva E. V. , Blatt J. E. 
Published: December 2018

Aim.The study was conducted for the characteristics of the morphoimmunohistochemical status of the implant from polylactic acid (PLA) located in the dermis.Materials and methods.The study was performed on rats (30 individuals) with subdermal administration of the drug in a volume of 0,05 ml. The results were evaluated after two weeks, 1 and 2 months after the injection. The sections were stained with hematoxylin and eosin, according to Van Gieson, with the help of Mallory and Masson reaction. Collagen fibers were studied after the staining with picrosirius red under polarized light. Monoclonal antibodies of CD 68 and antibodies to vimentin were used to determine the expression of immunohistochemical markers.Results. It is shown that the rate of collagen synthesis varies in different parts of the dermis. There is a sharp increase in the volume of the fibrous component around the implant, and there is only a tendency to increase in the synthesis in the implant itself. In this case, the increase in the volume of the extracellular matrix is associated with type I and III collagen.Conclusion.The detected activation of collagen synthesis by fibroblasts can be used as a regulator of the volume of the matrix, which is very important for the modern regenerative medicine.
THE SPECIFICITY OF THE OVARIAN RESERVE OF WOMEN WITH CHRONIC SALPINGOOPHORITIS
Authors: Novikova V. A. , Autleva F. R. , Sorochenko A. A. , Fayzullina D. I. , Nurgalieva E. V. 
Published: December 2018

Aim. The research was conducted for the assessment of the impact of chronic salpingoophoritis on the ovarian reserve of women in various phases of reproductive age.Materials and methods. A prospective, controlled and open cohort study was performed in 2013-2018 (n=202). The main group consisted of women with chronic salpingoophoritis (ChrSO) who applied for preconception consultation (n=138). In accordance with the reproductive age phase, the main group was divided into subgroups: the early reproductive age period (ERP, n=44), the peak reproductive age period (PRP, n=56), the late reproductive period (LRP, n=38). The control group consisted of conditionally healthy women of reproductive age (n=64). The ovarian reserve (OR) was estimated on the basis of the serum level of antimullerian hormone (AMH), inhibin B, estradiol, follicle stimulating hormone (FSH), an ultrasoundbased assessment of the number of antral follicles (AF), and the ovarian volume. Results. The age of women ranged from 18 to 40 years. Based on the discriminant analysis, it was found that the main indicators determining the specificity of the OR in ChrSO, depending on the phase of reproductive age, are the number of antral follicles, estradiol level and AMH (Wilks’ lambda = 0.35503, p<0.0001). The specificity of the OR of women with ChrSO (difference from the control group), regardless of the phase of reproductive age, initially and when evaluated after 6 months, is determined by the number of AF and the level of estradiol and AMH; the number of AF and AMH is determined with a similar estimate after 12 months. The specificity of the OR in ChrSO, which is dependent on the reproductive age phase, has been proved through the analysis with the neural networks training(the proportion of correct answers is more than 80%). The linear relationships were established between the values of each OR parameter in women with ChrSO. Initially, when estimating after 6 and 12 months, linear regression equations were calculated, allowing the values of individual OR parameters to be calculated over 6 and 12 months.Conclusion. Chronic salpingoophoritis (ChrSO) is associated with a decrease in ovarian reserve in women of reproductive age. The effect of ChrSO on some parameters of the ovarian reserve depends on the age phase of the reproductive period, which increases with time (after 6, 12 months). The presence of ChrSO in women planning future pregnancies requires preventive and therapeutic measures aimed at preserving the ovarian reserve and the preferred implementation of fertility in early reproductive age before the ovarian reserve starts to decline.
THE RESULTS OF A SURVEY OF SURGEONS ON THE SAFETY OF PHARMACOTHERAPY
Authors: Ochakovskaya I. N. , Durleshter V. M. , Ni O. G. , Shabanova N. E. 
Published: December 2018

Aim.The study was conducted to assess the level of awareness of surgeons about the principles of safe perioperative pharmacotherapy.Materials and methods. The survey of surgeons was conducted in 2018 on the basis of a questionnaire made by the authors, consisting of 60 questions and tasks, divided into 6 thematic blocks. The respondents had to demonstrate their knowledge both in the field of general principles of safe pharmacotherapy and private issues of using analgesics, anticoagulants, antibiotics in the perioperative period. The results of the survey were assessed as a percentage (proportion of correct answers) individually for each respondent and in total.Results.The results of the survey showed a lack of a deep understanding of the principles of safe pharmacotherapy in most clinical cases. Despite the fact that a number of answers completely correlated with the positions of evidence-based medicine, in general, there was a lack of systemic knowledge. The survey made it possible to identify those important points that should be first highlighted in the preparation of the training program.Conclusion.Every doctor should strive to minimize the preventable medical errors associated with pharmacotherapy. This is feasible only in the process of continuous daily learning. Practitioners' interest in the efficacy and safety of pharmacotherapy and mastering the basic decision-making algorithms for prescribing, controlling safety and cancelling drugs will improve the quality of medical care.
PROGRESS IN SURGICAL TREATMENT OF CHRONIC LOWER LIMB ISCHEMIA
Authors: Alukhanyan O. A. , Маrtyrosya X. G. , Poluektova I. V. , Avakimyan V. A. 
Published: December 2018

Aim. The study was conducted to expand the variety of ways for surgical treatment of chronic ischemia of lower limbs complicated by the involvement of the femoropopliteal and pedidial arterial segment. Materials and methods. The experience of surgical interventions in 43 male patients aged 52-75 suffering from chronic ischemia of lower limbs complicated by the atherosclerotic involvement of the femoropopliteal and pedidial segment has been summarized. According to the classification by A.V. Pokrovskiy, ischemia of the 3rd stage has been determined in 24 patients (55,8%), while ischemia of the 4th stage complicated by necrosis of the toes (critical ischemia) has been determined in other 19 patients (44,2%). All examined patients have undergone the reconstructive interventions using the prepared lateral subcutaneous vein of the upper extremity as a shunt.Results. During the first day after the operation, the regression of pain syndrome as well as the warming of the lower extremity was indicated in 93% of patients. In 8-12 days after the reconstructive operation, the patients have undergone the 15 necrectomy or toe amputation. In the nearest postoperative period (less than 6 months) no thrombotic complications in the reconstructed segment have been determined. Within the observation period from 6 months to 5 years the bypass patency has been preserved in 71% of patients; ischemia of the 2nd B type has been revealed in all patients with the preserved bypass patency by the clinical examination.Conclusion. Despite the “forced” character of usage of the prepared V. cephalica due to the absence of “traditional” venous shunts as well as the labor intensity of the method, it allows to expand the variety of ways for surgical treatment of patients suffering from chronic ischemia of lower limbs of the 3rd-4th stages complicated by occlusive involvements of the femoropopliteal and pedidial segment.
ANALYSIS OF MORBIDITY BY INFECTIOUS DERMATOSIS OF THE POPULATION OF KRASNODAR REGION IN THE LAST 5 YEARS
Authors: Gloozmin M. I. , Shevchenko A. G. , Egorova E. V. , Gloozminа M. M. 
Published: December 2018

Aim. The aim was to evaluate the epidemiological situation of dermatomycosis and scabies in Krasnodar region, to identify the tendencies and the development trend of the epidemiological situation, as well as the main directions of work retrospectively and in the dynamics of 2013-2017.Materials and methods. Statistical data forms №9, №34 in the last five years, which shape the incidence of contagious dermatoses in Krasnodar region, were used in the study. The morbidity rate of the population of the region is indirectly linked to macroeconomic and social objective and subjective processes in the society.Results. The analysis of the incidence of infectious skin diseases (hereinafter – ISD) shows a negative trend for scabies and major dermatomycosis, with the exception of mycosis of the feet and hands, in the studied five-year period. Structural analysis shows the ratio of sex-age categories of patients with different nosologies: the prevalence of the feet and hands mycoses in adult female patients and microsporia in male children. The link between the number of cases of contagious skin diseases and the territorial gradation of patients was considered. Conclusion. A retrospective analysis of the epidemiological situation of dermatomycosis and scabies in Krasnodar region was conducted. Gender, age and territorial aspects of contagious dermatoses, and the development trends were identified over the analyzed period. The factors contributing to the spread of contagious dermatoses were studied: climatic features of the southern region of the Russian Federation, migration flows, and socio-economic declines. The prospects of preventive work include raising public awareness and joint activities with non-medical services with an emphasis on active detection.
TACTICS OF THE SURGEON IN URGENT COMPLICATIONS OF COLON CANCER
Authors: Avakimyan V. A. , Karipidi G. K. , Avakimyan S. V. , Didigov M. T. , Alukhanyan O. A. 
Published: December 2018

Aim.The aim of the work is to develop the tactics for the treatment of complicated colon cancer (tumor perforation, tumor bleeding, acute obturation obstruction).Materials and methods. The clinical development included 324 patients with urgent complications of colon cancer. 269 patients were operated urgently and immediately, 56 operations were deferred. The diagnosis was based on anamnesis, clinical, laboratory and special research methods (ultrasound, CT, EGD, colonoscopy, histological examination).Results.Postoperative mortality in urgent complications of colon cancer was 3.5%.Conclusion.The rationale for the choice of method and volume of surgery, depending on the location and nature of complications of colon cancer, is provided.
ANALYSIS OF THE ADHESION OF MICROORGANISMS TO MODERN BASIC MATERIALS IN PROSTHETIC DENTISTRY
Authors: Zudin P. S. , Tsalikova N. A. , Mitronin V. A. , Chunikhin A. A. , Fokina T. Y. , Belozerova N. N. , Zudina M. N. , Kuvaeva M. N. 
Published: December 2018

Aim.The research was conducted for the study of the adhesion of samples of the domestic modern photopolymerizable base composite material in comparison with other materials for the manufacture of the denture bases.Materials and methods.Five samples of the materials were tested to conduct a microbiological study on the subject of primary adhesion of microorganisms to the surface of the base materials. The adhesion of microorganisms to the samples of the base composite materials was assessed using the index method.Results.As a result of a laboratory research, it can be concluded that the new photopolymerization material «Sample 1» used for the manufacture of the bases for the removable dentures has 1, 19 times lower adhesive activity to the colonyforming Prevotella intermedia microorganisms and Candida krusei mushrooms in comparison with the acrylic plastics and thermoplastic materials «Sample 2»; 1,14 times in comparison with the nylon material «Sample 3» and with the monomer material «Sample 4» with a statistically reliable variable number. It should be noted that the Axil-LC topcoat varnish supplied with the Sample 1 basic material kit increases microbial adhesion by 1.36 times.Conclusion.The adhesion of microorganisms to the materials that are used in dental practice is due to the surface tension coefficient – the greater the surface tension coefficient, the higher the probability of adhesion of microorganisms on the surface of these materials. The investigated new photopolymerization material «Sample 1» without coating with a protective varnish showed low adhesion to all major pathogens. Covering with a protective lacquer design, which is a part of the set of the material, significantly increases the adhesion of microorganisms on the surface of the material. The established indexes of microorganisms adhesion to the material «Sample 1» allow us to recommend it for the manufacture of bases for temporary dentures and immediate dentures in the treatment at the stages of dental implantation.
THE EFFECT OF STRESS PRESSURE ON THE FORMATION OF BOUND WATER IN KAOLIN CLAY
Authors: Seredin V. V. , Medvedeva N. A. , Anukhina A. V. , Andrianov A. V. 
Published: December 2018

Clays during lithogenesis change the composition, structure and properties, including the physicochemical ones. Some researchers present the results of studying changes in the properties of bound water in clays under the influence of increasing temperatures and pressures. When compaction of water-saturated clays, the “free” water of large pores is removed first, then under loads of 1–3 MPa -- osmotic water, and at a pressure of more than 10 MPa, the removal of “structured hydrated layers” of adsorption-bound water begins. According to the literature,several layers of water closest to a solid surface, corresponding to clay moisture close to “maximum hygroscopic” are not pressed by loads of tens of MPa, and “monolayers” of hundreds of MPa. However, despite existing publications on this issue, experimental information is notenough. The work is devoted to the influence of stress pressure on the formation of bound water in kaolin clay. In the course of experimental studies it was found that stress pressure has a multidirectional effect on the gradient of the removed mass of bound water in clays. This isdue to the fact that that when treating kaolin clay with stress pressure, defects are formed on the surface and “inside” of particles (aggregates, colloids and crystallites). Such surface imperfections form the energy potential of the particles, which determines the sorptionactivity of the clays. During the comparison of direct and indirect criteria, it was found that the most significant influence on the formation of the energy potential of particles is exerted by pressure in the range of P = 0 ÷ 125 MPa. With increasing load up to P = 800 MPa, it is quitedifficult to establish the effect of stress pressure on the formation of the energy potential. Thus, under technogenic impact on kaolin clay, its energy potential changes and, as a result, physicochemical properties, including the content of bound water.
The Doctrine and the Strategy as the Basis for Business Growth
Authors: Goloskokov L. V. 
Published: December 2018

The paper examines the Russian strategies and doctrines to see if they contain fundamental provisions that can stimulate the national business in general and business activities of individuals. The subject of the study is the errors of legislators caused by the fact that the multiplicity of strategies developed has converted the strategic approach to tactical approaches and led to the loss of the main goal fixed in Art. 7 of the Russian Constitution — building “a social State whose policy is aimed at creating conditions for a worthy life and a free development of man”. The purposes of the study were to assess the consequences of common and individual errors made by the legislators, reveal important provisions of the strategies lost during legal and economic transformations and find ways to solve problems encountered. It it concluded that the country’s development strategies should be revised and updated based on the constitutional provisions and with account for the interests of an ordinary person in order to enhance the business activity of all citizens and the national business as a whole.
Promotion of the Business Activity in Modern Russia: Successful Practices
Authors: Kolodnyaya G. V. 
Published: December 2018

The subject of the research is the practice of boosting the business activity in the medium-sized and small businesses in the domestic economy. The purpose of the research was to assess the effectiveness of financial and non-financial tools for supporting the business activity in the modern domestic economy. It is shown that the inefficiency of the Russian financial market is mitigated by the state through the formation of an institutional business-friendly environment and development institutions such as the Industrial Development Fund, the SME Corporation, the Russian Export Center, etc. The paper pays special attention to the assessment of the project related to the development of high-tech medium-sized companies — “National Champions”. It is concluded that in the modern domestic economy of the recent years the business vector tends to shift towards the preferential use of non-financial tools for supporting business activities.
Investigating the Influence of Penetration Length of Cut-off Wall on its Dynamic Interaction with Core and Foundation of Earth Dam
Authors: Javanmard Mehran , Mottaghi Reza , Hosseini S. M. Mir Mohammad 
Published: December 2018

Seepage and flow of water in the soil is one of the most important issue and effective elements in designing embankment dams. One of the methods to control seepage in alluvial foundation of earth dams is to use a plastic concrete cutoff-wall. For better seepage control, the cutoff-wall extends inside the clayey core as the one of common method of connection of cut-off wall and the core. Due to the stiffness difference of the core material and cutoff-wall, and also due to geological situation, physical and mechanical properties of rock and foundation, interaction of core and foundation with cut-off wall in different static and dynamic load cases is very considerable. Failure of cut-off wall occurs in cut-off wall and core joint. So the study of their interaction, especially during an earthquake is very important. Karkheh dam cut-off wall with an area of about 150000 m2 is chosen for this study. FLAC software has been used to study the effect of cutoff-wall penetration length variation, inside the clay core of Karkheh earth dam under dynamic loading. In numerical analysis of Karkheh earth dam model, all construction stages and seepage through dam are modelled. The model is first calibrated according to the results obtained from the dam instrumentations. After calibrating, according to available seismic studies of region, a suitable acceleration was selected and applied to the model. In this research, in order to find the optimum length, the effect of 0, 5, 10, 15 and 20 meters penetration length of cut-off wall in aforementioned conditions has been investigated. The results of the numerical study showed that the horizontal displacement and the maximum shear strain in the cutoff-wall is occurred adjacent to the clay core and the interface of core and foundation is a critical point for the cut-off wall, and also the stress in cut off wall joint increases with the elongation of penetration depth of the wall.
Análise matemática e realidade aumentada: um estudo no ensino superior em Portugal
Authors: Cardoso Teresa , Coimbra Teresa , Mateus Artur 
Published: December 2018

Neste texto, começamos por definir Realidade Aumentada (RA), enquadrando-a nas tecnologias tridimensionais, referindo a sua importância e atualidade. Depois, num breve estado da arte, apresentamos um mapeamento a partir de estudos que focam a RA em contextos educacionais, nomeadamente no ensino superior e no domínio da matemática.Posteriormente, descrevemos parte do estudo desenvolvido no âmbito do trabalho de doutoramento “As Tecnologias Tridimensionais como contributo para a aprendizagem da Matemática no Ensino Superior”, que teve como objetivo principal contribuir para uma compreensão mais profunda de como as tecnologias tridimensionais podem potenciar o ensino e a aprendizagem da Matemática, no contexto nacional do ensino superior, em particular na área das engenharias.Da análise dos nossos dados e resultados, foi possível concluir que os desafios que se colocam hoje ao nível dos métodos de ensino, da aquisição e consequente consolidação do conhecimento podem ser em parte (cor)respondidos com a aplicação de tecnologias disponíveis, como a RA, que permitam uma compreensão mais completa dos conteúdos, levando à endogeneização de conhecimento e também à internalização de competências com bases mais sólidas.
Yürüme Döngüsünün Alt Eksterimite Kemikleri Üzerindeki Kinematik Çözümlemesi
Authors: Özkan Arif , Söğüt Şener 
Published: December 2018

Diz eklemini oluşturan tüm yapılar
normal hareket edilmesinin sağlanmasında önemli rol oynarlar. Ortopedik olarak
normal bir insanın yürüme döngüsü femur ve tibia kemiklerinin bir dizi konum
değişim entegrasyonu ile ortaya çıkmaktadır. Bu çalışmada, normal bir alt
ekstremite dizilimine sahip bir insanın yürümesindeki dinamik kuvvet analizi
yapılmış ve diz eklemi kinematik çözümlemesi ele alınmıştır. Diz eklemi yatay eksen etrafında fleksiyon ve ekstansiyon yaparken ön düzlemde içe doğru kayma adı verilen abdüksiyon hareketi ile dışa doğru kayma olarak tanımlanan addüksiyon hareketini yapar. Tıbbi terminoloji olarak medial-lateral olarak tanımlanmış olan iç ve dış düzlemde ise sınırlı dönme yapar [6-12]. Kabul edilen bir terminoloji ile anlık dönme merkezi, diz eklemine aktarılan yükün dik olarak etkime yapmasını ve bağlar üzerine aşırı kuvvet aktarılmasını engelleme görevi görür. Diz aktif olarak 140°, pasif olarak 160° fleksiyon yapabilir [5-10].
Grid Connected Inverter
Authors: Evran Fatih 
Published: December 2018

This paper presents solar based single phase grid connected
inverter system. In such a system, DC-DC converter is both used to boost low PV
panel voltage and ensures that the solar panel operates at maximum power while Full
bridge inverter injects the maximum power from the solar panel to the grid. The
system is reliable because it does not cause control complexity and also it is preferred
to obtain a low THD (Total harmonic distortion). But, the main disadvantages of
the converters such as a boost or a flyback type are limited voltage gain and low
efficiency. In the proposed topology, the DC-DC converter with galvanic
insulation and high voltage gain characteristics can connect a low-voltage
solar panel to the grid. Simulation results are given for the system which
inverts MPPT voltage range of 20-30 V DC to grid voltage of 220 V(rms) at power
range of 60-300 W with a unity power factor.