bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlação entre coordenação motora e idade de pré-escolares no Norte do Brasil
Authors: Marinho Dias Joselia , Araújo de Souza Alesandra , Lucena Joana Marcela Sales de 
Published: November 2024

Objetivo: Analisar o desenvolvimento da coordenação motora grossa, a partir das baterias de teste PROESP-Br e Bateria psicomotora (BPM), de crianças em idade pré-escolar, de uma escola da região norte do Brasil. Métodos: Pesquisa quantitativa transversal. Foram utilizadas as baterias de teste Projeto Esporte Brasil (PROESP-Br) e Bateria Psicomotora (BPM). A bateria de testes da PROESP-BR foi utilizada para avaliar as variáveis: Índice de Massa Corporal (IMC), força de membros superiores (FMS), força de membros inferiores (FMI) e flexibilidade. A BPM foi utilizada para avaliar as habilidades: Equilibração, lateralização e praxia global, posteriormente classificadas em perfil hiperpráxico, eupráxico, dispráxico e apráxico. Resultados: Participaram do estudo 18 crianças com idade média de 5 anos (desvio padrão = 0,62). A força média de membros inferiores foi de 133 cm, 108 cm para a força de membros superiores e 72 cm para flexibilidade. Pela avaliação da BPM, mais de 50% das crianças tinham perfil hiperpráxico nos itens imobilidade, apoio retilíneo dos pés, equilíbrio dinâmico e lateralização pedal; Perfil eupráxico nos itens coordenação óculo pedal, Lateralização manual e Lateralização ocular; Perfil dispráxico nos itens Coordenação óculo manual, dissociação de membros superiores/inferiores e agilidade; E, por último, o perfil apráxico esteve mais prevalente na variável equilíbrio estático. Conclusão: A amostra apresentou níveis adequados de coordenação motora grossa em algumas atividades analisadas, mas em contrapartida, as habilidades Coordenação óculo manual, dissociação de membros superiores/inferiores e agilidade e equilíbrio estático tiveram resultados negativos, indicando que essas capacidades precisam ser desenvolvidas.
The use of four-pillar regimen for heart failure management: results from the Jordanian Heart Failure Registry (JoHFR)
Authors: Izraiq Mahmoud , Jammal Mustafa , Toubasi Ahmad A. , Mari Sae’ed , AlNajafi Sarah , Al-Qadasi Ayad , Al Maharmeh Khaled , Almansour Maha , Saleh Soadad , Ahmed Yaman , Abu-hantash Hadi 
Published: November 2024

Background
Heart failure (HF) is a complex cardiovascular disease. Effective management typically involves four main medications: angiotensin-converting enzyme inhibitors/angiotensin receptor blockers, beta-blockers, angiotensin receptor-neprilysin inhibitors, and mineralocorticoid receptor antagonists, along with sodium-glucose co-transporter-2 inhibitors (SGLT2i). The primary objective of this article is to assess and identify the utilization of four-pillar regimen for HF managment and explore the characteristics of the patients being on the four-pillar regimen in Jordan.

Methods
Data from the Jordanian HF registry (JoHFR) was analyzed, encompassing records of HF patients treated in various cardiology centers from 2021 to 2023.

Results
The medical records of 2,151 patients with HF who were admitted to cardiology centers throughout Jordan were collected. Males comprised 58.0% of the included patients. Moreover, 71.0% of patients had chronic HF, whereas the rest, 29.0%, had acute HF. Of these, only 0.6% received the complete four-pillar treatment of HF. Beta-blockers were the most frequently used medication, prescribed to 74% of patients, while SGLT2i were the least common, used by only 9%. Notably, patients with type 2 diabetes were more likely to be on the four-pillar regimen (P-value = 0.016). Additionally, patients with a glomerular filtration rate (GFR) below 60 were more likely to be treated using the four-pillar (P-values = 0.044). The analysis revealed no significant difference in mortality rates between the two groups (P-value = 0.475).

Conclusion
Our study demonstrated an overall low utilization of the four-pillar regimen for HF treatment in Jordan with several patients’ characteristics associated with it. This highlight the need for enhanced collaborative effort and governmental initiatives to address the challenges of the low utilization of these medications.
Functional Food Potential of Green Tea Waste (Used Tea Leaves) Through Lactic acid Fermentation
Authors: Saito Kieko , Nakamura Yoriyuki 
Published: November 2024

Aims: Fermented functional foods were developed to utilize green tea waste (used tea leaves) and their antioxidative activity was examined.
Methodology: The initial tea waste was prepared by steeping regular tea leaves in deionized water at 90°C for 60 s. This procedure was repeated to obtain the fifth and tenth sequential extracts. Subsequently, lyophilized tea leaves were rehydrated with potable water and inoculated with Lactococcus lactis subsp. cremoris. Following thorough mixing, the inoculated sample was fermented under anaerobic conditions at 25°C in the absence of light. To monitor the progress of fermentation, the pH levels of the infusion were measured on days 1, 3, 7, and 14. Additionally, the antioxidative activity of the fermented tea leaves and their infusions was assessed using the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging assay.
Results: After one week of lactic acid fermentation, the pH of the infusions from the fifth and tenth tea leaf extracts decreased significantly compared to other samples. However, within two weeks, all sample infusions reached a pH below 4, suggesting that catechins in the used tea leaves may inhibit lactic acid production during the early stages of fermentation. Despite the multiple extractions, the tea leaves from the fifth and tenth extracts retained elements that supported fermentation. Furthermore, the infusion prepared from the tea leaves after the tenth extract continued to exhibit antioxidative activity, indicating that beneficial properties persist even after repeated extractions.
Conclusion: Tea waste can be effectively utilized for lactic acid fermentation. Moreover, the resulting infusion may provide health benefits, making it a potential functional food.
Knowledge and Associated Factors of Diabetes Mellitus among HIV Clients Living with Diabetes in Eastern Uganda: A Cross-sectional Study
Authors: Okia David , Mwanzo Isaac , Olupot- Olupot Peter , Kimiywe Judith 
Published: November 2024

Introduction: Poor diabetes knowledge among diabetes clients living with HIV remains a big public health challenge in Africa. Effective self-management of diabetes requires clients to be knowledgeable about the recommended diets, exercises, drugs, lifestyle modifications, and possible diabetes complications. The proportion of diabetes clients living with HIV with poor diabetes knowledge is on the rise in Eastern Uganda. Poor level of diabetes knowledge among clients is a serious threat to individual health, and Knowledge is essential for effective control of diabetes, as it allows the patient to play an active and cooperative role in planning and monitoring the therapeutic, which promotes informed decisions
Aim: This study, conducted from May to June 2024, assessed the level of diabetes knowledge and its associated factors among diabetes clients living with HIV in Eastern Uganda.
Study Design: A cross-sectional study was conducted in Mbale and Soroti Regional Referral Hospitals in Eastern Uganda from May to June 2024.
Materials and Methods: The sample size was 267 registered participants though ten didn’t participate. Random sampling was done to select eligible registered participants. Electronic data collection was done by trained research assistants under the supervision of the principal investigator. All the research assistants were trained in data quality management. Ethical approval was obtained from Busitema University REC. The diabetes knowledge questionnaire was used to gather the data, and Stata version 14 was used for analysis. Univariate analysis and Binary logistic regression were used to identify associated factors. P <0.05 was considered statistically significant at a 95% confidence interval.
Results: A total of 257 participants in Mbale and Soroti Hospitals participated in this study. The majority 152(59.1%) were females and 156(60.7%) of these participants were above the age of 50 years. The married were 59.1%. Only 20.2% had tertiary education. More than half (58.4%) had a below-average level of knowledge regarding diabetes, 78.2% did not know how diabetes is managed and 58.4% were not aware of the common diabetes complications. In addition, 49.80% were not knowledgeable about the recommended diabetes tests, and 46.30% were not knowledgeable about the diets.
Conclusions: The level of knowledge about diabetes is low among diabetes people living with HIV at Mbale and Soroti Hospitals in Eastern Uganda. No factor was found to be significantly associated with low diabetes knowledge. Routine diabetes education by the facility's health workers is encouraged and the focus should be on recommended diabetes tests, diets, drugs and possible complications.
Contribution: Identifies specific areas to be strengthened in diabetes education.
Bio Efficacy of Bioagents against Sclerotium rolfsii: An Incitant of Stem Rot Disease in Groundnut
Authors: J. P. Divyasree , T. N. Usha , D. Rashmi , P. Yashwantha 
Published: November 2024

Aims: An experiment was carried out to know the bio efficacy of ten bio agents against Sclerotium rolfsii viz, Bacillus subtilis, Pseudomonas fluorescens, Bacillus megaterium, Bacillus velenzensis,Trichoderma longibrachiatum, Trichoderma hamatum, Trichoderma harzianum, Trichoderma afroharzianum,Trichoderma asperelloides, Trichoderma asperellum.
Study Design: The experiment was carried out in Completely Randomised Design with three replications.
Place and Duration of Study: During 2023-2024 at Department of Plant Pathology, College of Agriculture, Shivamogga.
Methodology: The research utilized 10 different bioagents sourced from the Department of Plant Pathology at the College of Agriculture in Shimoga.
Results: Statistically difference observed among the bio-agents evaluated with respect to per cent inhibition of mycelia growth of S. rolfsii. Among the fungal bioagents, the highest per cent inhibition of mycelial growth was observed in T. longibrachiatum (55.43%). Among bacterial bio-agents, Bacillus subtilis showed maximum inhibition (42.35 %).
Conclusion: This study indicates that fungal bioagents are more effective than bacterial bioagents in controlling the growth of pathogen.
Synthetische Kunststoffe (Plastik)
Authors: Braun Melanie , Amelung Wulf 
Published: December 2018

Jedes Jahr werden über 300 Mio t Plastik produziert. Es wird angenommen, dass hiervon bis zu 10 % in die Umwelt eingetragen werden wo Plastik aufgrund der hohen Persistenz akkumuliert. Hier fassen wir für Böden die wichtigsten Eintragspfade, Nachweismethoden, Gehalte sowie Reaktionen und Wirkung von Plastik zusammen. Dabei unterscheiden wir zwischen Nano‐ (<100 nm), kolloidalem (<1 µm), Mikro‐ (1 µm‐5 mm), Meso‐ (5‐25 mm) und Makroplastik (>2,5 cm). Nano‐ bis Mikroplastik werden primär z.B. für Hygienemittel produziert oder entstehen sekundär durch Zerkleinerung. Sie reichern sich in der Nahrungskette an, doch ihre Gehalte in Böden sind aufgrund fehlender Analyseverfahren bislang weitgehend unbekannt. Die gefundenen Gehalte an vorwiegend Mikroplastik und größeren Plastikteilen variieren dagegen beträchtlich, von 0–627,000 Teilen m‐3im Abwasser, von <3 bis >1200 mg kg‐1Kompost oder 1000 bis 24,000 Teilen kg‐1Klärschlamm. Risiken bestehen deshalb v.a. für solche Böden, die bevorzugten Eintragspfaden ausgesetzt sind. Für eine Gesamtbewertung jedoch fehlen bislang verlässliche Grenzwerte.
Euryale Ferox Seed‐Inspired Superlubricated Nanoparticles for Treatment of Osteoarthritis
Authors: Yan Yufei , Sun Tao , Zhang Hongbo , Ji Xiuling , Sun Yulong , Zhao Xin , Deng Lianfu , Qi Jin , Cui Wenguo , Santos Hélder A. , Zhang Hongyu 
Published: December 2018

AbstractOsteoarthritis has been regarded as a typical lubrication deficiency related joint disease, which is characterized by the breakdown of articular cartilage at the joint surface and the inflammation of the joint capsule. Here, inspired by the structure of the fresh euryale ferox seed that possesses a slippery aril and a hard coat containing starchy kernel, a novel superlubricated nanoparticle, namely poly (3‐sulfopropyl methacrylate potassium salt)‐grafted mesoporous silica nanoparticles (MSNs‐NH2@PSPMK), is biomimicked and synthesized via a one‐step photopolymerization method. The nanoparticles are endowed with enhanced lubrication by the grafted PSPMK polyelectrolyte polymer due to the formation of tenacious hydration layers surrounding the negative charges, and simultaneously are featured with effective drug loading and release behavior as a result of the sufficient mesoporous channels in the MSNs. When encapsulated with an anti‐inflammatory drug diclofenac sodium (DS), the lubrication capability of the superlubricated nanoparticles is improved, while the drug release rate is sustained by increasing the thickness of PSPMK layer, which is simply achieved via adjustment of the precursor monomer concentration in the photopolymerization process. Additionally, the in vitro and in vivo experimental results show that the DS‐loaded MSNs‐NH2@PSPMK nanoparticles effectively protect the chondrocytes from degeneration, and thus, inhibit the development of osteoarthritis.
Hydrogen‐Bonded Two‐Component Ionic Crystals Showing Enhanced Long‐Lived Room‐Temperature Phosphorescence via TADF‐Assisted Förster Resonance Energy Transfer
Authors: Zhou Bo , Yan Dongpeng 
Published: December 2018

AbstractMolecular room‐temperature phosphorescent (RTP) materials with long‐lived excited states have attracted widespread attention in the fields of optical imaging, displays, and sensors. However, accessing ultralong RTP systems remains challenging and examples are still limited to date. Herein, a thermally activated delayed fluorescence (TADF)‐assisted energy transfer route for the enhancement of persistent luminescence with an RTP lifetime as high as 2 s, which is higher than that of most state‐of‐the‐art RTP materials, is proposed. The energy transfer donor and acceptor species are based on the TADF and RTP molecules, which can be self‐assembled into two‐component ionic salts via hydrogen‐bonding interactions. Both theoretical and experimental studies illustrate the occurrence of effective Förster resonance energy transfer (FRET) between donor and acceptor molecules with an energy transfer efficiency as high as 76%. Moreover, the potential for application of the donor–acceptor cocrystallized materials toward information security and personal identification systems is demonstrated, benefitting from their varied afterglow lifetimes and easy recognition in the darkness. Therefore, the work described in this study not only provides a TADF‐assisted FRET strategy toward the construction of ultralong RTP, but also yields hydrogen‐bonding‐assembled two‐component molecular crystals for potential encryption and anti‐counterfeiting applications.
Is 3D Printing of Pharmaceuticals a Disruptor or Enabler?
Authors: Liang Kun , Brambilla Davide , Leroux Jean‐Christophe 
Published: December 2018

AbstractAdditive manufacturing (AM) is a fast‐growing manufacturing approach that comes with the promise of delivering personalized medicine to treat individual patients. However, large‐scale commercial applications in the pharmaceutical industry have been limited. Here, some of the challenges are discussed along with some pharmaceutical products where AM has the potential to make a tangible impact and pave the way for more rapid adoption are highlighted.
Impact of Post‐Lithography Polymer Residue on the Electrical Characteristics of MoS2 and WSe2 Field Effect Transistors
Authors: Liang Jierui , Xu Ke , Toncini Blaec , Bersch Brian , Jariwala Bhakti , Lin Yu‐Chuan , Robinson Joshua , Fullerton‐Shirey Susan K. 
Published: December 2018

AbstractThe residue of common photo‐ and electron‐beam resists, such as poly(methyl methacrylate) (PMMA), is often present on the surface of 2D crystals after device fabrication. The residue degrades device properties by decreasing carrier mobility and creating unwanted doping. Here, MoS2 and WSe2 field effect transistors (FETs) with residue are cleaned by contact mode atomic force microscopy (AFM) and the impact of the residue on: 1) the intrinsic electrical properties, and 2) the effectiveness of electric double layer (EDL) gating are measured. After cleaning, AFM measurements confirm that the surface roughness decreases to its intrinsic state (i.e., ≈0.23 nm for exfoliated MoS2 and WSe2) and Raman spectroscopy shows that the characteristic peak intensities (E2g and A1g) increase. PMMA residue causes p‐type doping corresponding to a charge density of ≈7 × 1011 cm−2 on back‐gated MoS2 and WSe2 FETs. For FETs gated with polyethylene oxide (PEO)76:CsClO4, removing the residue increases the charge density by 4.5 × 1012 cm−2, and the maximum drain current by 247% (statistically significant, p < 0.05). Removing the residue likely allows the ions to be positioned closer to the channel surface, which is essential for achieving the best possible electrostatic gate control in ion‐gated devices.
Scalable Graphene‐on‐Organometal Halide Perovskite Heterostructure Fabricated by Dry Transfer
Authors: Qin Liang , Kattel Bhupal , Kafle Tika R. , Alamri Mohammed , Gong Maogang , Panth Mohan , Hou Yanbing , Wu Judy , Chan Wai‐Lun 
Published: December 2018

AbstractGraphene, a single layer conductor, can be combined with other functional materials for building efficient optoelectronic devices. However, transferring large‐area graphene onto another material often involves dipping the material into water and other solvents. This process is incompatible with water‐sensitive materials such as organometal halide perovskites. Here, a dry method is used and succeeded, for the first time, in stacking centimeter‐sized graphene directly onto methylammonium lead iodide thin films without exposing the perovskite film to any liquid. Photoemission spectroscopy and nanosecond time‐resolved photoelectrical measurement show that the graphene/perovskite interface does not contain significant amount of contaminants and sustain efficient interfacial electron transfer. The use of this method in fabricating graphene‐on‐perovskite photodetectors is further demonstrated. Besides a better photoresponsivity compared to detectors fabricated by the conventional perovskite‐on‐graphene structure, this dry transfer method provides a scalable pathway to incorporate graphene in multilayer devices based on water‐sensitive materials.
Evidence for Primal sp2 Defects at the Diamond Surface: Candidates for Electron Trapping and Noise Sources
Authors: Stacey Alastair , Dontschuk Nikolai , Chou Jyh‐Pin , Broadway David A. , Schenk Alex K. , Sear Michael J. , Tetienne Jean‐Philippe , Hoffman Alon , Prawer Steven , Pakes Chris I. , Tadich Anton , de Leon Nathalie P. , Gali Adam , Hollenberg Lloyd C. L. 
Published: December 2018

AbstractMany advanced applications of diamond materials are now being limited by unknown surface defects, including in the fields of high power/frequency electronics and quantum computing and quantum sensing. Of acute interest to diamond researchers worldwide is the loss of quantum coherence in near‐surface nitrogen‐vacancy (NV) centers and the generation of associated magnetic noise at the diamond surface. Here for the first time is presented the observation of a family of primal diamond surface defects, which is suggested as the leading cause of band‐bending and Fermi‐pinning phenomena in diamond devices. A combination of density functional theory and synchrotron‐based X‐ray absorption spectroscopy is used to show that these defects introduce low‐lying electronic trap states. The effect of these states is modeled on band‐bending into the diamond bulk and it is shown that the properties of the important NV defect centers are affected by these defects. Due to the paramount importance of near‐surface NV center properties in a growing number of fields, the density of these defects is further quantified at the surface of a variety of differently‐treated device surfaces, consistent with best‐practice processing techniques in the literature. The identification and characterization of these defects has wide‐ranging implications for diamond devices across many fields.
Archimedean Spiral Inspired Conductive Supramolecular Elastomer with Rapid Electrical and Mechanical Self‐Healing Capability for Sensor Application
Authors: Han Yangyang , Wu Xiaodong , Zhang Xinxing , Lu Canhui 
Published: December 2018

AbstractIn addition to flexibility and stretchability, self‐healing capability will become another characteristic for next‐generation electronics and devices. However, developing electronic materials with both good mechanical and electrical self‐healing abilities still remains a great challenge yet an exciting goal. Herein, a new kind of self‐healing conductive elastomer via alliance of supramolecular chemistry and Archimedean spiral‐structure design is reported to break the trade‐off between mechanical and electrical healing capabilities. The spirally structured conductive layout enables the material to rapidly self‐heal both mechanical (within 15 s) and electrical (within 0.25 s) damages with high efficiency, while without sacrificing the softness and stretchability of the self‐healing elastomer matrix. As a proof‐of‐concept, such materials can be used to fabricate self‐healable wearable sensors for monitoring diverse human activities. The rapidly, efficiently, mechanically, and electrically self‐healing materials demonstrated in this work facilitate the design and application of a wide range of stretchable and reliable electronic devices.
Deterministic Arrays of Epitaxially Grown Diamond Nanopyramids with Embedded Silicon‐Vacancy Centers
Authors: Jaffe Tzach , Felgen Nina , Gal Lior , Kornblum Lior , Reithmaier Johann Peter , Popov Cyril , Orenstein Meir 
Published: December 2018

AbstractThe negatively charged silicon‐vacancy center (SiV) in diamond is a potential high‐quality source of single‐indistinguishable photons for quantum information processing and quantum electrodynamics applications. However, when embedded in bulk diamond, this emitter suffers from both, relatively low extraction efficiency attributed to total internal reflection as well as nondeterministic location. On the other hand, its implementation in nanodiamonds is impeded by optical dephasing owing to their degraded surface quality. Here a robust and deterministic template‐assisted bottom‐up process for the creation of high‐quality diamond nanopyramids incorporating SiVs is reported. This method employs a predefinition of high‐precision nanopillars by e‐beam lithography and dry etching, and subsequent epitaxial overgrowth during which Si atoms are introduced into diamond. The overgrown layer, including the nanopyramid arrays, is epitaxial as confirmed by comprehensive analyses. This diamond nanopyramid, hosting the SiVs, can pave the way toward efficient localized single‐photon source arrays and potentially outshine nanodiamonds and nanosized structures prepared by a top‐down method. The lateral confinement of the SiVs inside the deterministic nanosized pyramids enables their positioning at the center of cavities and optical structures for enhanced quantum efficiency and light–matter manipulation, and their employment as a system to explore collective coherent interactions between ensembles and confined light.