bluuebunny/crossref_metadata_2025_split huggingface dataset:
Qualitative and quantitative diagnosis of nitrogen nutrition of tea plants under field condition using hyperspectral imaging coupled with chemometrics
Authors: Wang Yu‐Jie , Li Tie‐Han , Jin Ge , Wei Yu‐Ming , Li Lu‐Qing , Kalkhajeh Yusef K , Ning Jing‐Ming , Zhang Zheng‐Zhu 
Published: August 2019

AbstractBACKGROUNDRapid and accurate diagnosis of nitrogen (N) status in field crops is of great significance for site‐specific N fertilizer management. This study aimed to evaluate the potential of hyperspectral imaging coupled with chemometrics for the qualitative and quantitative diagnosis of N status in tea plants under field conditions.RESULTSHyperspectral data from mature leaves of tea plants with different N application rates were preprocessed by standard normal variate (SNV). Partial least squares discriminative analysis (PLS‐DA) and least squares–support vector machines (LS‐SVM) were used for the classification of different N status. Furthermore, partial least squares regression (PLSR) was used for the prediction of N content. The results showed that the LS‐SVM model yielded better performance with correct classification rates of 82% and 92% in prediction sets for the diagnosis of different N application rates and N status, respectively. The PLSR model for leaf N content (LNC) showed excellent performance, with correlation coefficients of 0.924, root mean square error of 0.209, and residual predictive deviation of 2.686 in the prediction set. In addition, the important wavebands of the PLSR model were interpreted based on regression coefficients.CONCLUSIONOverall, our results suggest that the hyperspectral imaging technique can be an effective and accurate tool for qualitative and quantitative diagnosis of N status in tea plants. © 2019 Society of Chemical Industry
Small and large strain rheology of gluten and gluten–starch doughs containing wheat bran dietary fiber
Authors: Ma Sen , Han Wen , Li Li , Wang Xiaoxi 
Published: August 2019

AbstractBACKGROUNDThe small and large strain rheology of gluten (G) and gluten–starch (G + S) doughs containing wheat bran dietary fiber (WBDF) were investigated.RESULTSAt the small strain stage, i.e. frequency and strain sweep tests, the doughs containing high WBDF concentration are more vulnerable and unstable, as indicated by the lower dough linear viscoelastic strain limit as well as the higher slope of elastic modulus. However, the elastic nature of doughs remarkably increased upon WBDF addition, indicating the reinforcement of the dough mechanical strength, which is also confirmed by the large strain test wherein the maximum strain significantly decreased from 4.37 to 1.82 for the G system and from 12.09 to 2.72 for the G + S system. The creep recovery test showed that WBDF induced the reduction in the strain of the doughs at a fixed stress, which may be related to the enhanced strain hardening capacity.CONCLUSIONThe addition of WBDF resulted in more brittle and unstable doughs with undesirable higher mechanical strength. The presence of starch greatly weakened the dough strength and led to inferior resistance to both small and large deformations. These findings confirmed the impairment of dough viscoelasticity upon addition of WBDF. © 2019 Society of Chemical Industry
Spatial patterns in soil physicochemical and microbiological properties in a grassland adjacent to a newly built lake
Authors: Li Jinsheng , An Chan , Shang Jianying , Zhao Tianchi , Zhang Qian , Yang Xiaomeng , Ren Cheng , Huang Ding , Liu Kesi , Shao Xinqing 
Published: August 2019

AbstractSoil water content (SWC) is an important determinant for nutrient cycling and microorganism activity in the grassland ecosystem. Lakes have a positive effect on the water supply of the neighboring ecosystem. However, information evaluating whether newly built lakes improve the physiochemical properties and microorganism activity of adjacent grassland soil is rare. A 15‐hectare artificial lake with a 2 m depth was built on grazed grassland to determine whether the change of soil physiochemical properties and microorganism activity of the adjacent grassland depended on the distance from the lake. SWC and total nitrogen (TN) were greater within 150 m of the lake than at distances over 150 m from the lake. The total organic carbon (TOC) increased first at 100–150 m from the lake and then decreased. The soil microbial biomass and the bacterial and fungal contents increased with increasing years after the construction of the lake. Gram‐negative bacteria and methanotrophic bacteria were greater within a 30 m distance of the lake. Over 60 m away from the lake, Actinobacteria, gram‐positive bacteria, and anaerobic bacteria showed higher abundances. In the area near the lake (<250 m distance), microorganisms were strongly correlated with SWC, EC, TN, and TOC and greatly correlated with the changes of total phosphorous (TP) and pH when the distance from the lake was over 250 m. The results indicated that the newly built lake could be a driving factor for improving the physiochemical properties and microorganism activity of adjacent grassland soil within a certain range.
Changes in Prescribing Practices of Dopaminergic Medications in Individuals with Parkinson's Disease by Expert Care Centers from 2010 to 2017: The Parkinson's Foundation Quality Improvement Initiative
Authors: Dubaz Ornella M. , Wu Samuel , Cubillos Fernando , Miao Guanhong , Simuni Tanya ,   the Parkinson's Foundation Quality Improvement Initiative Investigators
Published: August 2019

ABSTRACTBackgroundDuring the past decade, there has been increasing awareness of the side effects of dopamine agonists (DAs), including impulse control disorders. We hypothesized that there may be a shift toward more conservative use of DAs.ObjectiveTo explore the change in prescribing practices for dopaminergic medications in Parkinson's disease between 2010 and 2017.MethodsData were collected from the Parkinson's Foundation Quality Improvement Initiative registry. Baseline characteristics were compared between the 2010 and 2017 cohorts using chi‐squared tests for discrete and t tests for continuous variables. Logistic regressions were conducted for each class of medications to assess the effect of time points (2010 vs. 2017) and prespecified covariates on the probability of prescribing.ResultsA total of 2,717 participants from 2010 and 2,900 participants from 2017 were included in the analysis. Mean (standard deviation) age was 67.4 (10) and 68.7 (9.3) for the 2010 and 2017 cohorts, respectively (P < 0.0001). After controlling for baseline characteristics, DA use was unchanged (P = 0.1172). The odds of using monoamine oxidase B inhibitors was 52% higher in 2017 than in 2010 (P < 0.0001), 38% lower for catechol‐O‐methyltransferase inhibitors (P < 0.0001), 25% lower for amantadine (P < 0.0001), and 31% lower for anticholinergics (P = 0.0153). There was no difference in the utilization of levodopa in the 2 cohorts (86.1% vs. 86.2%; P = 0.5783).ConclusionsDespite increasing awareness of impulse control disorders, there has been no reduction in the use of DAs during the past decade. Overall, there is less utilization of adjunctive classes of drugs except for an increase in the use of monoamine oxidase B inhibitors.
Simple quad‐band bandpass filter implemented on a 50‐Ω microstrip line
Authors: Sung Youngje 
Published: August 2019

AbstractIn this study, we implement a compact quad‐band bandpass filter (BPF) on a 50‐Ω microstrip line. The proposed structure comprises an input/output stage with one end terminated at a 50‐Ω C‐shaped open‐loop resonator. When the gap between the input stage and the output stage is located at the center and the filter structure is symmetric, it acts as a dual‐band BPF, but when the gap moves and the filter structure becomes asymmetric, it acts as a quad‐band BPF. The proposed structure is very small in size because it is implemented on a 50‐Ω line without any additional space. Even though it supports four frequency bands, the design complexity is minimized by reducing the number of design parameters. In addition, analysis of the current distribution and parameter study suggest a method to control only one or two specific resonant frequencies among four resonant frequencies. The fabricated BPF demonstrates four passbands located at 1.5, 3.6, 5.4, and 7.2 GHz. Within the four passbands, the minimum insertion losses are 0.2, 0.6, 1.8, and 1.7 dB, respectively.
Tumor mutational burden assessed by targeted NGS predicts clinical benefit from immune checkpoint inhibitors in non‐small cell lung cancer
Authors: Alborelli Ilaria , Leonards Katharina , Rothschild Sacha I , Leuenberger Laura P , Savic Prince Spasenija , Mertz Kirsten D , Poechtrager Severin , Buess Martin , Zippelius Alfred , Läubli Heinz , Haegele Jasmin , Tolnay Markus , Bubendorf Lukas , Quagliata Luca , Jermann Philip 
Published: August 2019

AbstractIn non‐small cell lung cancer (NSCLC), immune checkpoint inhibitors (ICIs) significantly improve overall survival (OS). Tumor mutational burden (TMB) has emerged as a predictive biomarker for patients treated with ICIs. Here, we evaluated the predictive power of TMB measured by the Oncomine™ Tumor Mutational Load targeted sequencing assay in 76 NSCLC patients treated with ICIs. TMB was assessed retrospectively in 76 NSCLC patients receiving ICI therapy. Clinical data (RECIST 1.1) were collected and patients were classified as having either durable clinical benefit (DCB) or no durable benefit (NDB). Additionally, genetic alterations and PD‐L1 expression were assessed and compared with TMB and response rate. TMB was significantly higher in patients with DCB than in patients with NDB (median TMB = 8.5 versus 6.0 mutations/Mb, Mann–Whitneyp = 0.0244). 64% of patients with high TMB (cut‐off = third tertile, TMB ≥ 9) were responders (DCB) compared to 33% and 29% of patients with intermediate and low TMB, respectively (cut‐off = second and first tertile, TMB = 5–9 and TMB ≤ 4, respectively). TMB‐high patients showed significantly longer progression‐free survival (PFS) and OS (log‐rank testp = 0.0014 for PFS and 0.0197 for OS). While identifying different subgroups of patients, combining PD‐L1 expression and TMB increased the predictive power (from AUC 0.63 to AUC 0.65). Our results show that the TML panel is an effective tool to stratify patients for ICI treatment. A combination of biomarkers might maximize the predictive precision for patient stratification. Our study supports TMB evaluation through targeted NGS in NSCLC patient samples as a tool to predict response to ICI therapy. We offer recommendations for a reliable and cost‐effective assessment of TMB in a routine diagnostic setting. © 2019 The Authors.The Journal of Pathologypublished by John Wiley & Sons Ltd on behalf of Pathological Society of Great Britain and Ireland.
Impact of meteorological and geographical factors on the distribution of leishmaniasis's vector in mainland China
Authors: Gao Xiang , Huang Yuran , Zheng Jiahao , Xiao Jianhua , Wang Hongbin 
Published: August 2019

AbstractBACKGROUNDPhlebotomine sandfly (Diptera: Psychodidae) is best known for its role as the vector of the leishmaniasis. Leishmaniasis is a global disease, currently known to be affecting 88 countries and 12 million people worldwide.RESULTSThis study explored the impacts of climate factors and landscape on the local abundance of Phlebotomine sandfly in mainland China. A presence‐only modelling method was used to evaluate this species' habitat preferences from environmental factors. Jackknife analysis revealed that several biologically meteorological variables, including the maximum temperature of the warmest quarter, the precipitation in the driest month, the daily average temperature and daily precipitation, would significantly affect the existence of this species. Moreover, the existence of Phlebotomine sandfly was significantly associated with grassland and forest.CONCLUSIONThe results will improve scientific understanding of the risks of the spread of leishmaniasis over current infected areas and can be used to design more detailed surveillance programmes and more evidence‐based control planning for Phlebotomine sandfly and leishmaniasis. © 2019 Society of Chemical Industry
Evaluation of long‐term protection from nursery to vineyard provided by Trichoderma atroviride SC1 against fungal grapevine trunk pathogens
Authors: Berbegal Mónica , Ramón‐Albalat Antonio , León Maela , Armengol Josep 
Published: August 2019

AbstractBACKGROUNDFungal grapevine trunk diseases (GTDs) represent a threat to viticulture, being responsible for important economic losses worldwide. Nursery and vineyard experiments were set up to evaluate the ability of Trichoderma atroviride SC1 to reduce infections of GTD pathogens in grapevine planting material during the propagation process and to assess the long‐term protection provided by this biocontrol agent on grapevine plants in young vineyards during two growing seasons.RESULTSReductions of some GTD pathogen incidence and severity were found on grapevine propagation material after nursery application of T. atroviride SC1 during the grafting process, and also after additional T. atroviride SC1 treatments performed during two growing seasons in young vineyards, when compared with untreated plants.CONCLUSIONTrichoderma atroviride SC1 showed promise to reduce infections caused by some GTD pathogens in nurseries, and also when establishing new vineyards. This biological control agent could possibly be a valuable component in an integrated management approach where various strategies are combined to reduce GTD infections. © 2019 Society of Chemical Industry
Emerging pollutants—Part II: Treatment
Authors: Liu Bo , Zhang Shen‐gen , Chang Chein‐Chi 
Published: August 2019

AbstractRecently, emerging pollutants (EPs) have been frequently detected in urban wastewater, surface water, drinking water, and other water bodies. EPs mainly usually include pharmaceuticals and personal care products, endocrine‐disrupting chemicals, antibiotic resistance genes, persistent organic pollutants, disinfection by‐products, and other industrial chemicals. The potential threat of EPs to ecosystems and human health has attracted worldwide attention. Therefore, how to treat EPs in various water bodies has become one of the research priorities. In this paper, some research results on treatment of EPs published in 2018 were summarized.Practitioner points

At present, more attention has been paid to emerging pollutants (EPs), including pharmaceuticals and personal care products (PPCPs), endocrine‐disrupting chemicals (EDCs), antibiotic resistance genes, persistent organic pollutants, disinfection by‐products, etc.

Existing EPs disposal technologies mainly include: engineered wetlands and natural systems, biological treatment, physical and physicochemical separation, chemical oxidation, catalysis, etc.

This paper reviews some research results on the treatment technologies of EPs published in 2018.
Nitrification in a biofilm‐enhanced highly loaded aerated lagoon
Authors: Patry Bernard , Lessard Paul , Vanrolleghem Peter A. 
Published: August 2019

AbstractA full‐scale biofilm‐enhanced aerated lagoon using fixed submerged media was monitored using automated water quality monitoring stations over the span of one year to quantify its nitrification performance. The system was operating at a high organic loading rate averaging 5.8 g total CBOD5/m2 of media per day (23.9 g total CBOD5/m3 of lagoon per day), a total ammonia nitrogen loading rate averaging 0.9 g NH4‐N/m2 day (3.7 g NH4‐N/m3 day), and temperatures ranging from 1.6 to 20.8°C. The system showed an extended seasonal nitrification period compared with a simulated aerated lagoon system of the same dimensions. This extension of complete nitrification with approximately 1 month was observed in the fall despite the decrease of operating temperature down to 4°C. During this maximum nitrification period, substantial denitrification occurred, and the effluent un‐ionized ammonia ratio was reduced. A temporary loss of nitrification was also experienced in relation to an episode of elevated suspended solids concentration. Measured biofilm characteristics, namely the detachment dynamics and the biofilm thickness, were used to explain this temporary nitrification loss. During wintertime, a low nitrate production was still observed, suggesting year‐long retention of nitrifying bacteria in the biofilm.Practitioner points

Nitrification in a highly loaded biofilm‐enhanced aerated lagoon is mainly affected by operating temperature. Maximum nitrification is observed during the warmer months and occurs even at high organic loading rates (>5 g CBOD5/m2 day).

Compared with a simulated suspended growth system, the biofilm‐enhanced lagoon shows a significantly extended nitrification period. The extension is observed at the end of the summertime maximum nitrification period.

Low amounts of nitrate still produced during winter in the biofilm‐enhanced aerated lagoon suggest year‐long retention of autotrophic nitrifying biomass in the biofilm.

Nitrification in the biofilm‐enhanced aerated lagoon is negatively impacted by the presence of important quantities of accumulated solids that resuspend when their digestion starts as temperature increases.
High rate of biological removal of sulfate, organic matter, and metals in UASB reactor to treat synthetic acid mine drainage and cheese whey wastewater as carbon source
Authors: Sampaio Gabriela F. , dos Santos Angelica M. , da Costa Patricia R. , Rodriguez Renata P. , Sancinetti Giselle P. 
Published: August 2019

AbstractThe anaerobic biological treatment of sulfate‐rich effluents, such as acid mine drainage (AMD), is mediated by sulfate‐reducing bacteria (SRB). This process involves the reduction of sulfates in the presence of an electron donor. Complex carbon compounds can be used as electron donors. In the present study, was used an upflow anaerobic sludge blanket (UASB) reactor to co‐treat a low‐pH synthetic AMD and cheese whey wastewater (CWW). Were observed higher sulfate and COD removal rates (1,114 ± 88 and 1,214 ± 128 mg L−1 day−1, respectively) at higher sulfate and applied COD loading rates (1,500 mg L−1 day−1). The overall pH of the effluent remained above 6.4 without any bicarbonate supplementation. Almost 100% of the Fe, Zn, and Cu was removed and the presence of metals improved the process. The use of a single reactor to treat AMD and CWW is promising.Practitioner points

Wastewater cheese whey was electron donor for treating acid mine drainage in an UASB reactor.

Metals additions in the system indicated an increased removal of COD.

About 99% of the metals were removed with the treatment.
Re-evaluation of the Dutch approach: are recently referred transgender youth different compared to earlier referrals?
Authors: Arnoldussen Marijn , Steensma Thomas D. , Popma Arne , van der Miesen Anna I. R. , Twisk Jos W. R. , de Vries Annelou L. C. 
Published: August 2019

AbstractThe background of this article is to examine whether consecutively transgender clinic-referred adolescents between 2000 and 2016 differ over time in demographic, psychological, diagnostic, and treatment characteristics. The sample under study consisted of 1072 adolescents (404 assigned males, 668 assigned females, mean age 14.6 years, and range 10.1–18.1 years). The data regarding the demographic, diagnostic, and treatment characteristics were collected from the adolescents’ files. Psychological functioning was measured by the Child Behaviour Check List and the Youth Self-Report, intensity of gender dysphoria by the Utrecht Gender Dysphoria Scale. Time trend analyses were performed with 2016 as reference year. Apart from a shift in sex ratio in favour of assigned females, no time trends were observed in demographics and intensity of dysphoria. It was found, however, that the psychological functioning improved somewhat over time (CBCL β − 0.396, p < 0.001, 95% CI − 0.553 to − 0.240, YSR β − 0.278, p < 0.001, 95% CI − 0.434 to − 0.122). The percentage of referrals diagnosed with gender dysphoria (mean 84.6%, range 75–97.4%) remained the same. The percentage of diagnosed adolescents that started with affirmative medical treatment (puberty suppression and/or gender-affirming hormones) did not change over time (mean 77.7%; range 53.8–94.9%). These findings suggest that the recently observed exponential increase in referrals might reflect that seeking help for gender dysphoria has become more common rather than that adolescents are referred to gender identity services with lower intensities of gender dysphoria or more psychological difficulties.
Technical trading and cryptocurrencies
Authors: Hudson Robert , Urquhart Andrew 
Published: August 2019

AbstractThis paper carries out a comprehensive examination of technical trading rules in cryptocurrency markets, using data from two Bitcoin markets and three other popular cryptocurrencies. We employ almost 15,000 technical trading rules from the main five classes of technical trading rules and find significant predictability and profitability for each class of technical trading rule in each cryptocurrency. We find that the breakeven transaction costs are substantially higher than those typically found in cryptocurrency markets. To safeguard against data-snooping, we implement a number of multiple hypothesis procedures which confirms our findings that technical trading rules do offer significant predictive power and profitability to investors. We also show that the technical trading rules offer substantially higher risk-adjusted returns than the simple buy-and-hold strategy, showing protection against lengthy and severe drawdowns associated with cryptocurrency markets. However there is no predictability for Bitcoin in the out-of-sample period, although predictability remains in other cryptocurrency markets.
Acculturation, identity distress, and internalizing symptoms among resettled adolescent refugees
Authors: Guler Jessy , Berman Steven L. 
Published: August 2019

ABSTRACTIntroductionThis study examines the relations among native and host country acculturation, identity distress, and internalizing symptoms among multicultural adolescent refugees (N = 33) resettled to the United States from a range of countries including Cuba, Iraq, Jordan, Haiti, Colombia, and Venezuela. Despite previous research supporting the advantages of developing a bicultural style to acculturation, mixed results have been found regarding native and host country acculturation patterns among resettled refugees and how these patterns may be associated with refugee mental health outcomes.MethodsThe objective of this study was not only to consider the roles that US and native acculturation may play on the self‐report of identity distress and internalizing symptoms among refugee adolescents more broadly, but also to consider the role various dimensions of acculturation (e.g., cultural identity, language competence, and cultural competence) may play for refugee adolescents post‐resettlement.Results and ConclusionsThe study findings indicate that native acculturation, and more specifically native cultural identity, may serve as significant protective factors against identity distress among adolescent refugees post‐resettlement, with native cultural identity additionally serving as a protective factor against internalizing symptoms. US acculturation was not found to be significantly associated with identity distress or internalizing symptoms, nor were the acculturative dimensions of language learning (i.e., English and native language competencies), cultural knowledge (i.e., US and native cultural knowledge competencies), or US cultural identity. Recommendations and implications for practice and future research are discussed.