bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconfigurer la cartographie de la Franco-Amérique : la représentation de l'espace et du récit identitaire dans <em>Nikolski</em> de Nicolas Dickner
Authors: Thibeault Jimmy 
Published: June 2019

Le roman Nikolski de Nicolas Dickner met en scène la destinée croisée de trois personnages qui, ne se reconnaissant pas dans les espaces traditionnels qu’ils habitent, en viennent à reconfigurer la cartographie de leur appartenance intime au continent américain. Cette reconfiguration ne semble cependant possible que par la réactualisation d’un discours de l’origine puisé dans un passé marginalisé de la Franco-Amérique : c’est effectivement à travers les figures du Métis au territoire perdu et de l’Acadien devenu pirate dans la foulée du Grand Dérangement que les personnages se reconnaîtront. Ce sont ces figures singulières, réactivées par les personnages, qui constituent les balises de la nouvelle cartographie identitaire plurielle que trace, à travers une série de chassés-croisés, la narration de Nikolski. Abstract Nicolas Dickner’s novel Nikolski presents the shared destinies of three characters who, because they do not recognize themselves in the traditional places they inhabit, end up reconfiguring the cartography of their intimate belonging to the American continent. This reconfiguration, however, appears only possible through the reactualization of a discourse of the origins that draws on a marginalized past of Franco America. Indeed, it is only thanks to the figures of the Métis carving out his existence in a lost territory and the Acadian turning into a pirate on the heels of the Grand Dérangement that the characters will find their bearings. These singular figures, who the characters bring to life, constitute beacons in a new, plural cartography of identity that is mapped out by Nikolski’s narration through a series of to-ings and fro-ings.
Le pouvoir démiurgique d'un critique : Arthur Buies, personnage de Claude-Henri Grignon
Authors: Livernois Jonathan 
Published: June 2019

Écrivain majeur du 19e siècle canadien-français, Arthur Buies occupe une place étonnante dans la mémoire culturelle québécoise : ses écrits ont pour la plupart été oubliés et il est devenu un personnage du téléroman Les Belles Histoires des Pays d’en Haut; il est devenu le comédien Paul Dupuis, qui l’interpréta de 1956 à 1962 à la télévision. Cette étude met en relief le rôle de Claude-Henri Grignon dans cet « assassinat » et dans cette « résurrection » au cœur de la fiction. Abstract Important writer of the French-Canadian’s 19th century, Arthur Buies has a unique place in Quebec’s cultural memory: if his works were mostly forgotten, he became a TV’s character during 6 years (1956-1962) in Les Belles Histoires des Pays d’en Haut; he became Paul Dupuis, the actor. We want to explain Claude-Henri Grignon’s role in this « assassinat » and in this « résurrection » in the fiction.
Conducta frente a la prueba de Papanicolaou
Authors: Mahecha-Gamboa Lorena , Villate-Soto Steffany , Puerto-Jiménez Devi 
Published: June 2019

Objetivo: describir la conducta frente a la toma de citología de cuello uterino de las mujeres que acuden a un centro de atención primaria de la localidad de Suba. Metodología: estudio descriptivo observacional de corte transversal a través de la aplicación de una encuesta a 100 mujeres que asistieron para la toma de la citología a un punto de atención primaria en salud de una localidad de la ciudad de Bogotá. Resultados: el 94 % de las mujeres conoce el objetivo de la prueba, el 60 % de las encuestadas refieren temor al resultado. La principal razón por la cual las participantes deciden no tomarse la citología son barreras socioculturales. Conclusiones: a pesar que la mayoría de las mujeres manifestaron conocer la importancia de realizarse el examen y deciden voluntariamente acceder a él, expresan experimentar diferentes sentimientos catalogados como negativos frente a este; la pena, la vergüenza y el miedo al dolor son impedimentos principales que limitan el acceso a la prueba de Papanicolaou; no obstante, más de la mitad de las participantes refieren sentir temor a los resultados de dicho examen.
Ortaokul Öğrencileri için Matematiğe Yönelik Tutum Ölçeğini Türkçe’ye Uyarlama Çalışması
Authors: ŞEN Özgür 
Published: June 2019

Bu çalışmada, Yáñez-Marquina &amp; Villardón-Gallego tarafından geliştirilen “Ortaokul Öğrencileri için Matematiğe Yönelik Tutum Ölçeği (Scale for Assessing Attitudes towards Mathematics in Secondary Education(SATMAS)” ni Türk kültürüne uyarlama çalışması yapılmıştır. Çalışma, 5, 6, 7 ve 8. sınıfta öğrenim gören 878 ortaokul öğrencisinden alınan veriler ile gerçekleştirilmiştir. Açımlayıcı faktör analizi ve doğrulayıcı faktör analizleri uygulanarak ölçeğin yapı geçerliliği incelenmiştir. Ölçeğin özgün formu19 maddeden oluşmaktadır. Analizler doğrultusunda 1 madde ölçekten çıkarılarak dilimiz uyarlamasında 18 madde yer almıştır. Çalışmanın sonucunda, uyarlanması yapılan ölçeğin faktör yapısı, özgün yapısıyla tutarlı 3 faktörlü (öz benlik, algılanan faydası ve ilgi) model oluşturduğu görülmüştür. Doğrulayıcı faktör analizi sonuçları ölçeğin literatürde istenilen uyum indekslerini sağlamaktadır. Güvenirlik çalışmasına göre ölçeğin Cronbanch alfa değeri 0.91 olarak hesaplanmıştır. Elde edilen bulgular, uyarlanan ölçeğin ortaokul öğrencilerinin matematiğe yönelik tutumlarını ölçmek için alternatif, kullanışlı, uygulanması kolay, geçerli ve güvenilir bir araç olduğu sonucuna ulaşmıştır.
Impact of toothpaste on oral health-related quality of life in people with dentine hypersensitivity
Authors: Mason Stephen , Burnett Gary R. , Patel Nisha , Patil Avinash , Maclure Robert 
Published: June 2019

Abstract
Background

Dentine hypersensitivity can impact functional status and everyday activities such as eating and talking. This study aimed to assess changes in oral health-related quality of life measures in individuals with dentine hypersensitivity following long-term use (24 weeks) of a commercially available toothpaste marketed for dentine hypersensitivity relief.

Methods

This study was conducted across two sites and enrolled 75 adults with ≥2 non-adjacent sensitive teeth. Participants were assigned to twice-daily brushing with toothpaste containing 0.454% w/w stannous fluoride (1100 ppm fluoride). Every 4 weeks, participant-reported outcomes were assessed using the Dentine Hypersensitivity Experience Questionnaire (DHEQ), a condition specific oral health-related quality of life scale that has five domains and includes questions on social and emotional impact, restrictions, adaptations and effect on life overall. Responses to a clinically applied evaporative (air) stimulus were assessed using the examiner-observed Schiff sensitivity scale and Labelled Magnitude Scales (LMS), which included dentine hypersensitivity-specific descriptors of intensity, duration, tolerability and descriptive qualities of the participant’s response.

Results

Participant-reported outcomes demonstrated reduction of the impact of dentine hypersensitivity over time on health-related quality of life, as measured by the DHEQ. This reached statistical significance from Week 8 onwards (p<0.0001 versus baseline) for the Total DHEQ score, with scores continually decreasing at each timepoint. Most domain scores followed a similar pattern. Statistically significant reductions were also detected for the examiner-observed Schiff Sensitivity Scale scores at all timepoints (including at 4 weeks) (p<0.05), which were mirrored by LMS responses. The toothpaste was generally well-tolerated.

Conclusions

These results show that long-term use of a sensitivity toothpaste containing 0.454% w/w stannous fluoride has a beneficial, ongoing, impact on the oral health-related quality of life of people with dentine hypersensitivity.
Does a Bilateral Polypropylene Mesh Alter the Duct Deferens Morphology, Testicular Size and Testosterone Levels? Experimental Study in Rats
Authors: Damous Sergio Henrique Bastos , Damous Luciana Lamarão , Miranda Jocielle Santos , Montero Edna Frasson de Souza , Birolini Claudio , Utiyama Edivaldo Massazo 
Published: June 2019

Abstract
Background

The impact of hernia repair with a polypropylene (PP) mesh on testicular function and fertility remains uncertain, regardless of the technique used. This study evaluated the effect of a PP mesh on duct deferens morphology, testicular size and testosterone levels.

Methods

Forty adult male Wistar rats were distributed into groups according to the surgical procedure: 1) no surgery; 2) inguinotomy; 3) mesh placed on the duct deferens; and 4) mesh placed on the spermatic funiculus. After 90 postoperative days, the inguinal region was resected, and blood samples were collected for the measurement of serum testosterone (pg/dl). The testicle was measured with a pachymeter in the longitudinal and transverse directions to calculate its size (mm). The duct deferens were isolated and sectioned in three axial sections according to the relationship with the mesh — cranial, medial and caudal (1 cm above, at the segment where the mesh was placed, and 1 cm below, respectively). The wall thickness and duct deferens lumen area were measured.

Results

The morphology of the duct deferens was preserved in all groups. The mesh placement did not alter this morphology in any of the analyzed segments. In nonoperated animals, there was an anatomic reduction in the wall thickness of the duct deferens in the caudal segment (p<0.05 1/3 cranial and medial vs. caudal). Surgery, with or without mesh placement, did not alter the morphology, wall thickness or lumen area (p>0.05). In all operated groups, there was a decrease in testicle size (p<0.05); however, the serum testosterone levels were similar among the groups (p>0.05).

Conclusion

Surgery, with or without mesh placement, did not alter the morphology of the duct deferens and, although this treatment resulted in testicular size reduction, it did not affect serum testosterone levels. Future studies should deepen the analysis of the effect of the mesh on the functionality of these organs and the real impact on male fertility.
Prediction of Kidney Transplant Outcome Based On Different DGF Definitions In Chinese Deceased Donation
Authors: Hu Xiao-jun , Zheng Jin , Li Yang , Tian Xiao-hui , Tian Pu-xun , Xiang He-li , Pan Xiao-ming , Ding Chen-guang , Ding Xiao-ming , Xue Wujun 
Published: June 2019

Abstract
Background

Delayed graft function (DGF) is an important complication of kidney transplantation and can be diagnosed according to different definitions. DGF has been proven to be associated with the long-term outcome of kidney transplantation surgery. However, the best DGF definition for predicting renal transplant outcomes in Chinese donations after cardiac death (DCDs) remains to be determined.

Method

A total of 182 DCD kidney transplants from January 2015 to December 2015 in the First Affiliated Hospital of Xi’an Jiaotong University were diagnosed with DGF according to 6 different DGF definitions. The relationship of the DGF definitions to the three-year graft loss (GL) and 12-month estimated glomerular filtration rate (eGFR) posttransplantation was compared.

Results

The incidence of DGF varied from 5.01% to 50.89% according to the different DGF diagnoses. All DGF definitions were significantly associated with three-year GL and had considerable predictive power for a poorer transplant outcome. None of the DGF definitions were significantly better than the dialysis-based DGF definition.

Conclusion

DGF was a independent risk factor for poorer transplant outcome. In the Chinese DCD population, no definitions were superior to the universally accepted one, namely, the need for hemodialysis in the first week posttransplantation. Combination of need for hemodialysis within the first week and 48h serum creatinine reduction rate has a better predictive value for graft loss.
Interactions between plant defense and prior herbivory alter conditions for a plant virus and its vector
Authors: Shi Xiaobin , Preisser Evan L. , Liu Baiming , Pan Huipeng , Xiang Min , Xie Wen , Wang Shaoli , Wu Qingjun , Li Chuanyou , Liu Yong , Zhou Xuguo , Zhang Youjun 
Published: June 2019

Abstract
Background: While virus-vector-host interactions have been a major focus of both basic and applied ecological research, little is known about how different levels of plant defense interact with prior herbivory to affect these relationships. We used genetically-modified strains of tomato (Solanum lycopersicum) varying in the jasmonic acid (JA) plant defense pathways to explore how plant defense and prior herbivory affects a plant virus (tomato yellow leaf curl virus, 'TYLCV'), its vector (the whitefly Bemisia tabaci MED), and the host.
Results: Virus-free MED preferred low-JA over high-JA plants and had lower fitness on high-JA plants. Viruliferous MED preferred low-JA plants but their survival was unaffected by JA levels. While virus-free MED did not lower plant JA levels, viruliferous MED decreased both JA levels and the expression of JA-related genes. Infestation by viruliferous MED reduced plant JA levels, and TYLCV loads were consistently higher in plants fed upon by viruliferous MED than in plants fed on by virus-free MED. In preference tests, neither virus-free nor viruliferous MED discriminated among JA-varying plants previously exposed to virus-free MED. However, both virus-free and viruliferous MED preferred low-JA plant genotypes when choosing between plants that had both been previously exposed to viruliferous MED. The enhanced preference for low-JA genotypes appears linked to the volatile compound neophytadiene, which was found only in whitefly-infested plants and at concentrations inversely related to plant JA levels.
Conclusions: Our findings illustrate how plant defense can interact with prior herbivory to affect both a plant virus and its whitefly vector, and confirm the induction of neophytadiene by lower JA that may prove useful in pest detection and management.
Thicknesses of macular inner retinal layers in children with anisometropic amblyopia
Authors: Xia Zheren , Chen Hao , Zheng Suilian 
Published: June 2019

Abstract
Background

To investigate the thicknesses of macular inner retinal layers in children with anisometropic amblyopia through spectral-domain optical coherence tomography (SD-OCT).

Methods

Thirty-seven children with anisometropic amblyopia and fifty-seven children with normal vision participated in the study. Both eyes of children with amblyopia and the right eyes of children with normal vision underwent scanning with the Spectralis OCT (Heidelberg Engineering, Heidelberg, Germany). The segmentation of retinal layers was performed automatically to measure individual inner retinal layers in the five sectors of the macula. An independent-sample t-test was used to compare measurements of anisometropic eyes and fellow eyes with control eyes.

Results

There was no significant difference in the total macular thickness in the five sectors between amblyopic and control eyes. However, in the peripheral macular area, three of the four quadrants of both the ganglion cell layer (GCL) and the inner plexiform layer (IPL) thickness were significantly reduced in amblyopic eyes than in control eyes. Moreover, two of the four quadrants of the GCL thickness and three of the four quadrants of the IPL thickness in the peripheral macular area were significantly reduced in fellow eyes than in control eyes.

Conclusions

The SD-OCT data revealed differences in the thicknesses of some macular inner retinal layers in both eyes of children with anisometropic amblyopia compared with those with emmetropia, indicating that structural changes might exist in the retina of children with amblyopia.
Genome-Wide identification and analysis of the AHL gene family in cotton (Gossypium)
Authors: Zhao Lanjie , Lu Youjun , Chen Wei , Yao Jinbo , Li Yan , Li Qiulin , Pan Jingwen , Fang Shengtao , Sun Jie , Zhang Yongshan 
Published: June 2019

Abstract
Background: Members of the AT-HOOK MOTIF CONTAINING NUCLEAR LOCALIZED (AHL) family are involved in various plant biological processes via protein-DNA and protein-protein interaction. However, the systematic identification and analysis of AHL gene family have yet not to be reported in cotton.
Results: To investigate the potential functions of AHLs in cotton, genome-wide identification, expressions and structure analysis of the AHL gene family were performed in this study. 48, 51 and 99 AHL genes were identified from the G.raimondii, G.arboreum and G.hirsutum genome respectively. Phylogenetic trees showed that the AHLs in cotton evolved into 2 clades, Clade-A with 4-5 introns and Clade-B with intronless (excluding AHL20-2). Based on the composition of the AT-hook motif(s) and PPC/DUF 296 domain, AHL proteins were classified into three types (Type-I/-II/-III), with Type-I AHLs forming Clade-B, and the other two types together diversifying in Clade-A. The detection of synteny and collinearity showed that the AHLs expanded with specific WGD in cotton, and AHL20-2 showed the tendency of increasing intron in three different Gossypium spp. The ratios of non-synonymous (Ka) and synonymous (Ks) substitution rates of orthologous gene pairs revealed that the AHL genes of G.hirsutum had undergone through various selection pressures, purifying selection mainly in A-subgenome and positive selection mainly in D-subgenome. Examination of their expression patterns showed most of AHLs of Clade-B expressed predominantly in stem, while those of Clade-A in ovules, suggesting that the AHLs within each clade shared similar expression patterns with each other. qRT-PCR analysis further confirmed that some GhAHLs higher expression in stems and ovules.
Conclusion: In this study, 48, 51 and 99 AHL genes were identified from three cotton genomes respectively. AHLs in cotton were classified into two clades by phylogenetic relationship and three type based on the composition of motif and domain. The AHLs expanded with segmental duplication, not tandem duplication. The expression profiles of GhAHLs revealed abundant differences in expression levels in various tissues and at different stages of ovules development. Our study provided significant insights into the potential functions of AHLs in regulating the growth and development in cotton.
Neuropilin 1 modulates TGF-β1-induced epithelial–mesenchymal transition in non-small cell lung cancer
Authors: Ding Zongli , Du Wenwen , Lei Zhe , Zhang Yang , Zhu Jianjie , Zeng Yuanyuan , Wang Shengjie , Zheng Yulong , Liu Zeyi , Huang Jian-an 
Published: June 2019

Abstract
Background: TGF-β1 signaling is a potent inducer of epithelial-mesenchymal transition (EMT) in various cancers. Our previous study has indicated that NRP1 was significantly up-regulated and acted as a vital promoter in the metastasis of non-small cell lung cancer (NSCLC). However, the function of NRP1 in regulation of TGF-β1-induced EMT and NSCLC cell migration and invasion remained unclear.
Methods: The differential expression level of NRP1 was determined by RT-PCR analysis in human tissue samples with or without lymph node metastasis. Transwell assay and wound healing assay were conducted to determine cell ability of migration. Lentivirus-mediated stable knockdown and overexpression of NRP1 cell lines were constructed. Exogenous TGF-β1 stimulation, SIS3 treatment, western blot analysis and in vivo metastatic model were utilized to clarify the underlying regulatory mechanism.
Results: Increased expression of NRP1 was found in metastatic NSCLC tissues and can promote NSCLC metastasis in vivo. Transwell assays, wound healing assay and western blot analysis showed that knockdown of NRP1 significantly inhibited TGF-β1-mediated EMT and migratory and invasive capabilities of A549 and H226 cells. Furthermore, overexpression of NRP1 could weak the decreased migratory and invasive capabilities with SIS3 treatment. Co-IP data showed that NRP1 can interact with TGFβRⅡ to induce EMT.
Conclusion: This is the first time to report that NRP1 can modulate TGF-β1-induced EMT and cell migration and invasion in NSCLC.
Changes in Vessel Density of the Patients with Narrow Antenior Chamber after an Acute Intraocular Pressure Elevation Observed by OCT Angiography
Authors: Ma ziwei , QIU WENHAN , ZHOU DANNI , YANG WEIHUA , PAN XUEFENG , CHEN HONG 
Published: June 2019

Abstract
Background:Although the pathogenesis of glaucoma is not fully understood ,an elevated intraocular pressure (IOP) is a major factor contributing to its development and progression. The aim of this study was to investigate the changes in the vessel densities of the macula and optic nerve head (ONH) after an acute elevation in the intraocular pressure (IOP) observed using optical coherence tomography angiography (OCTA).
Methods: This was a prospective comparative study of subjects with narrow anterior chamber angles who underwent laser peripheral iridotomies (LPIs). The IOP was measured before and one hour after the LPI. The retinal vessel densities of the macula and ONH were measured using OCTA at the baseline and one hour after the LPI.
Results: A total of 64 eyes of 51 individuals were enrolled in this study, and 58 eyes of 43 individuals finally completed the study with a mean IOP rise of 10.5 ± 7.6 mmHg after the LPI. Based on the magnitude of the rise in the IOP, we divided the subjects into three groups: group A = IOP rise ≤ 10 mmHg, group B = 10 mmHg < IOP rise ≤ 20 mmHg, and group C = IOP rise > 20 mmHg. The vessel density did not differ after the acute IOP elevation in either the macular region or papillary region in group A or group B (p > 0.05), but there was a significant difference in group C (p < 0.05). However, when the subjects were not separated into groups, the vessel densities of the ONH and macular region did not differ between the measurements obtained at the baseline and one hour after the LPI (p>0.05). The correlation existed in peripapillary and macular vessel density (p < 0.05).
Conclusion: In these subjects with narrow antenior chamber, an acute mild or moderate IOP elevation for one hour after the LPI did not affect the vessel density in the macula or ONH, as examined using OCTA. However, when the IOP rise was greater than 20 mmHg, the macular and papillary vessel density decreased significantly.