bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of a medialized middle turbinate on olfactory function: a prospective randomized double‐blind study
Authors: Kim Sang‐Wook , Kim Rock Bum , Kang Hyunmo , Cho Hyun‐Jin , Joo Yeon‐Hee , Jeon Yung Jin , Jeon Sea‐Yuong 
Published: January 2019

BackgroundMedialization of the middle turbinate (MT) is an effective technique to prevent recurrent rhinosinusitis but could, in theory, reduce olfactory function by interfering the odorants to reach the olfactory mucosae. We performed a prospective randomized double‐blind trial under the hypothesis that olfactory functions would be affected by the status of olfactory mucosae, not by MT medialization.MethodsIn randomly selected sides, the unilateral MT was medialized in 80 patients undergoing bilateral endoscopic sinus surgery for chronic rhinosinusitis. The status of the bilateral olfactory cleft (OC) was photodocumented intraoperatively and categorized into patent (normal or mucosal swelling with discharge) and congested (hypertrophied mucosae or nasal polyps) groups. The butanol threshold test (BTT) was conducted in each nostril before and 6 months after the surgery. Correlation between the BTT scores and MT medialization or the OC status was assessed. No smell identification test was conducted side by side, which might limit clinical implications.ResultsIn total, 46 of 80 patients completed the trial. MT medialization was performed on the left and right side of the nose in 19 and 27 cases, respectively. The intraoperative OC status did not differ between the 2 sides. Perioperative changes in the BTT scores were similar between the medialized and intact MT sides, whereas the preoperative and postoperative BTT scores were higher in the patent OC group than in the congested OC group, regardless of side.ConclusionMT medialization does not impair olfactory function, and OC status is closely related to olfactory function.
Metabolic patterns and seizure outcomes following anterior temporal lobectomy
Authors: Cahill Varduhi , Sinclair Benjamin , Malpas Charles B. , McIntosh Anne M. , Chen Zhibin , Vivash Lucy E. , O'Shea Marie F. , Wilson Sarah J. , Desmond Patricia M. , Berlangieri Salvatore U. , Hicks Rodney J. , Rowe Christopher C. , Morokoff Andrew P. , King James A. , Fabinyi Gavin C. , Kaye Andrew H. , Kwan Patrick , Berkovic Samuel F. , O'Brien Terence J. 
Published: January 2019

ObjectiveWe investigated the relationship between the interictal metabolic patterns, the extent of resection of 18F‐fluorodeoxyglucose positron emission tomography (18FDG‐PET) hypometabolism, and seizure outcomes in patients with unilateral drug‐resistant mesial temporal lobe epilepsy (MTLE) following anterior temporal lobe (TL) resection.MethodsEighty‐two patients with hippocampal sclerosis or normal magnetic resonance imaging (MRI) findings, concordant 18FDG‐PET hypometabolism, and at least 2 years of postoperative follow‐up were included in this 2‐center study. The hypometabolic regions in each patient were identified with reference to 20 healthy controls (p < 0.005). The resected TL volume and the volume of resected TL PET hypometabolism (TLH) were calculated from the pre‐ and postoperative MRI scans coregistered with interictal 18FDG‐PET.ResultsStriking differences in metabolic patterns were observed depending on the lateralization of the epileptogenic TL. The extent of the ipsilateral TLH was significantly greater in left MTLE patients (p < 0.001), whereas right MTLE patients had significantly higher rates of contralateral (CTL) TLH (p = 0.016). In right MTLE patients, CTL hypometabolism was the strongest predictor of an unfavorable seizure outcome, associated with a 5‐fold increase in the likelihood of seizure recurrence (odds ratio [OR] = 4.90, 95% confidence interval [CI] = 1.07–22.39, p = 0.04). In left MTLE patients, greater extent of resection of ipsilateral TLH was associated with lower rates of seizure recurrence (p = 0.004) in univariate analysis; however, its predictive value did not reach statistical significance (OR = 0.96, 95% CI = 0.90–1.02, p = 0.19).InterpretationThe difference in metabolic patterns depending on the lateralization of MTLE may represent distinct epileptic networks in patients with right versus left MTLE, and can guide preoperative counseling and surgical planning. Ann Neurol 2019; 1–10 ANN NEUROL 2019;85:241–250.
Double Perovskite LaFexNi1−xO3 Nanorods Enable Efficient Oxygen Evolution Electrocatalysis
Authors: Wang Huaping , Wang Juan , Pi Yecan , Shao Qi , Tan Yueming , Huang Xiaoqing 
Published: January 2019

AbstractPerovskite‐based electrocatalysts are one of the most promising materials for oxygen evolution reaction (OER), but their activity and durability are still far from desirable. Herein, we demonstrate that the double perovskite LaFexNi1−xO3 (LFNO) nanorods (NRs) can be adopted as highly active and stable OER electrocatalysts. The optimized LFNO‐II NRs with Ni/Fe ratio of 8:2 achieve a low overpotential of 302 mV at 10 mA cm−2 and a small Tafel slope of 50 mV dec−1, outperforming those of the commercial Ir/C. The LFNO‐II NRs also show high OER stability with slight current decrease after 20 h. The enhanced activity is explained by the improved surface area, tailored electronic structure as well as strong hybridization between O and Ni.
Solid‐State Synthesis of Two Different Polymers in a Single Crystal: A Miscible Polymer Blend from a Topochemical Reaction
Authors: Hema Kuntrapakam , Sureshan Kana M. 
Published: January 2019

AbstractThe topochemical synthesis of a miscible polymer blend is described. The azide‐ and alkyne‐decorated tetrol 1 crystallizes as two different conformers. Both conformers exhibit self‐sorted head‐to‐tail alignment with proximally placed reacting groups such that topochemical polymerization yields two types of polymer chains, each containing only one type of conformer. The orientation of complementary reactive groups in one of the head‐to‐tail‐arranged conformers favors the formation of cis‐triazole linkages, and the other favors the trans‐triazole linkages. Crystals of 1 on heating gave a perfect polymer blend containing equal amounts of cis‐triazole‐linked and trans‐triazole‐linked polymers. As each conformer is H‐bonded to four conformers of the other kind, the polymerization yields a perfect polymer blend wherein each polymer chain is surrounded by chains of the other type. Thus, the molecular ordering in the prepolymerized state in a crystal is utilized to create a polymer blend.
Optimizing adsorptive removal of malachite green and methyl orange dyes from simulated wastewater by Mn‐doped CuO‐Nanoparticles loaded on activated carbon using CCD‐RSM: Mechanism, regeneration, isotherm, kinetic, and thermodynamic studies
Authors: Sharifpour Ebrahim , Alipanahpour Dil Ebrahim , Asfaram Arash , Ghaedi Mehrorang , Goudarzi Alireza 
Published: January 2019

In the present work, Mn‐doped CuO‐NPs‐AC was prepared by a simple method, characterized using various techniques such as FESEM, EDX, XRD, PSD, and pHpzc and finally used for the adsorption of malachite green (MG) and methyl orange (MO) in a number of single and binary solutions. A series of adsorption experiments were conducted to investigate and optimize the influence of various factors (such as different pH, concentration of MG and MO, adsorbent mass, and sonication time) on the simultaneous adsorption of MG and MO using response surface methodology. Under optimal conditions of pH 10, adsorbent dose of 0.02 g, MG concentration of 30 mg L−1, MO concentration of 30 mg L−1, and sonication time of 4.5 min at room temperature, the maximum predicted adsorption was observed to be 100.0%, for both MG and MO, showing that there is a favorable harmony between the experimental data and model predictions. The adsorption isotherm of MO and MG by Mn‐doped CuO‐NPs‐AC could be well clarified by the Langmuir model with maximum adsorption capacity of 320.69 mg g−1 and 290.11 mg g−1 in the single solution and 233.02 mg g−1 and 205.53 mg g−1 in the binary solution by 0.005 g of adsorbent mass for MG and MO, respectively. Kinetic studies also revealed that both MG and MO adsorption were better defined by the pseudo‐second order model for both solutions. In addition, the thermodynamic constant studies disclosed that the adsorption of MG and MO was likely to be influenced by a physisorption mechanism. Eventually, the reusability of the Mn‐doped CuO‐NPs‐AC after six times showed a reduction in the adsorption percentage of MG and MO.
Recent Advancements in and the Future of Organic Emitters: TADF‐ and RTP‐Active Multifunctional Organic Materials
Authors: Data Przemyslaw , Takeda Youhei 
Published: January 2019

AbstractOrganic emitting compounds that are based on π‐conjugated skeletons have emerged as promising next‐generation materials for application in optoelectronic devices. In this Minireview, recent advances in the development of organic emitters that irradiate room‐temperature phosphorescence and/or thermally activated delayed fluorescence with extraordinary luminescence properties, such as aggregation‐induced emission, mechanochromic luminescence, and circularly polarized luminescence, are discussed.
Pedagogy of Bayes’ rule, confusion matrix, transition matrix, and receiver operating characteristics
Authors: Shankar P. Mohana 
Published: January 2019

AbstractA module has been developed to expand the scope of the undergraduate course in engineering probability to include data analytics. Starting with demos using data from hypothetical experiments in machine vision, students were exposed to the topics of confusion matrix, transition matrix, receiver operating characteristic curves, Bayes’ rule, and concepts of random variables bridging the gap between theory and applications. Student were given unique data sets requiring estimation of a priori and conditional probabilities, positive predictive values, and error rates in the machine vision classifier. Student surveys conducted at the start and conclusion of the course seem to suggest that they gained an enhanced understanding of the applications of probability concepts to data analytics. The methodology can easily be extended to cover other topics such as hypothesis testing and diversity analysis to shift the emphasis of the engineering probability course from pure theory to applications.
Composites of Anthraquinone Dyes@HKUST‐1 with Tunable Microstructuring: Experimental and Theoretical Interaction Studies
Authors: Loera‐Serna Sandra , Flores Jorge , Navarrete‐López Alejandra M. , Díaz de León Jorge Noé , Beltran Hiram I. 
Published: January 2019

AbstractThe metal–organic framework (MOF) HKUST‐1 was employed as an interaction matrix for fundamental loading studies of anthraquinone dyes. Chosen dyes were alizarin (A), alizarin S (AS), disperse blue 1 (B1), disperse blue 3 (B3), disperse blue 56 (B56) and purpurin (P). All materials were characterized by XRD, FTIR, TGA and SEM. Hence the interaction of dyes with the framework was characterized by theoretical–experimental differential analysis. One‐pot loading strategy resulted in more efficient scavenging of dyes, and reached 100 % for B56 using 50 mg L−1. SEM revealed important microstructural changes, the smaller crystals ranged 0.8–3 μm in size and almost all composite sizes were from this to higher values, reaching 70 μm, with varying shapes. Two composites were larger in size range (about 2500–1000 μm), and were shaped as rods, octahedrons and coffin lids. Indeed, the microstructure could be modulated depending on preparation conditions and type of loaded dye. For the higher loading series, N2 adsorption and XPS experiments were carried on to further evidence dye–MOF interactions. Ab initio prediction of structural properties for A@HKUST‐1 and P@HKUST‐1 were obtained by means of solid‐state CRYSTAL14 code at the PBE0 level of theory. Computed findings evidenced two O→Cu coordinative bonds, one from O‐ketone and the other from O‐phenolate moiety as main interactions towards CuNET centers.
Stable Singlet Biradicals of Rare‐Earth‐Fused Diporphyrin‐Triple‐Decker Complexes with Low Energy Gaps and Multi‐Redox States
Authors: Lee Sunri , Yamashita Ken‐ichi , Sakata Naoya , Hirao Yasukazu , Ogawa Kaya , Ogawa Takuji 
Published: January 2019

AbstractDinuclear rare‐earth (TbIII, YIII) triple‐decker complexes with a fused diporphyrin (FP) and two tetraphenylporphyrin (TPP) ligands were synthesized in neutral, dianionic, and diprotonated forms. The neutral forms have large open shell biradical character, as determined from the temperature dependency of the magnetic susceptibility measurements and theoretical calculations. The coupling value (J=−1.4 kcal mol−1, −487 cm−1) of the radical centers in the neutral form of the YIII complex indicates weak pairing interactions. Theoretical calculations on the neutral form reveal a significant biradical character (y=68 %). Furthermore, the TbIII complex exhibits multi‐redox states, having more than eight clear peaks in the voltammetry curves. The optical (3700 nm, 0.33 eV) and electrochemical measurements (3400 nm, 0.36 eV) indicate that the neutral form has very small HOMO–LUMO energy gap. Despite the large biradical character, the neutral complexes are thermally stable and do not decompose on heating at 120 °C. These complexes with unique characteristics are promising candidates for use in molecular electronics, optics, and spintronics.
First‐Row Transition‐Metal Cations (Co2+, Ni2+, Mn2+, Fe2+) and Graphene (Oxide) Composites: From Structural Properties to Electrochemical Applications
Authors: Sarac Oztuna F. Eylul , Yagci M. Baris , Unal Ugur 
Published: January 2019

AbstractComposites of graphene (oxide) (GO) and first‐row transition‐metal cations (Co2+, Ni2+, Mn2+, Fe2+) are prepared by mixing GO and aqueous metal salt solutions. The amount of metal cation bound to GO nanosheets is calculated by using inductively coupled plasma mass spectrometry (ICP‐MS) and the possible binding sites of the metals are investigated by means of attenuated total reflectance infrared (ATR‐IR) spectroscopy and X‐ray photoelectron spectroscopy (XPS) measurements. Electrodes loaded with the metal/GO composites are prepared by a simple drop‐casting technique without any binders or conductive additives. The effect of electrochemical reduction on the structure of the composite electrodes is investigated by Raman spectroscopy, XPS, X‐ray diffraction (XRD) analysis, and field emission scanning electron microscopy (FESEM). A detailed electrochemical characterization is performed for the utilization of the composite electrodes for electrochemical capacitors and possible oxygen reduction reaction electrocatalysts by cyclic voltammetry (CV) and rotating disk electrode measurements. The highest areal capacitance is achieved with the as‐deposited Fe/GO composite (38.7 mF cm−2 at 20 mV s−1). In the cyclic stability measurements, rCo/GO, rNi/GO, rMn/GO, and rFe/GO exhibit a capacitance retention of 44, 1.1, 73, and 87 % after 3000 cycles of CV at 100 mV s−1, respectively.
Investigation of gas condensate drop‐out effect on gas relative permeability by Lattice Boltzmann modelling
Authors: Soleimani Rasa , Norouzi Sevda , Rasaei Mohammad Reza 
Published: January 2019

AbstractIn a gas condensate reservoir, a drastic pressure drop in the vicinity of the wellbore makes it subject to gas condensate drop‐out. This phenomenon can adversely affect the productivity of the well and reduce gas recovery. The objective of this paper is to conduct a two‐phase fluid flow simulation on two‐dimensional porous media to understand the effect of the gas condensate drop‐out on the gas relative permeability values. In order to do so, lattice Boltzmann (LB) modelling was applied as a computational fluid dynamics (CFD) approach to perform the simulations in homogeneous and heterogeneous porous structures. The developed model was constrained by periodic boundary conditions at inlet and outlet and bounce‐back boundary condition at fluid‐solid interfaces. It was shown that the model can appropriately monitor formation and movement of the condensate droplets as a result of the pressure drop as well as blockages due to the entrance of the droplets into the throats. A consistent decrease in gas relative permeability values with condensate saturation was observed. It was also indicated that the condensate droplets become mobile at higher critical saturations in the heterogeneous system due to the dominance of capillary forces over viscous forces in the less permeable areas. Such dominance results in more severe blockages in the heterogeneous systems, as the simulation results confirmed.
Effect of color attributes on the buying decision model for Durio zibethinus L.
Authors: Theerathammakorn Supawadee , Hansuebsai Aran , Hoshino Yasushi 
Published: January 2019

AbstractPrinted images of food products appearing on packaging usually include vivid colors in order to draw the attention of customers and influence their buying decisions on the product. Buying decisions on Durio zibethinus L. or Durian cv. Monthong are not instantaneous. Packaging designers and marketers need to understand how color stimuli impact the customer's buying decision process. The color attributes of durian images, such as hue, saturation, and intensity based on HSI color system were evaluated for examining the color and generating stimuli. A psychophysical experiment was conducted based on the feelings of “deliciousness,” “attractiveness,” and “naturalness” from the packaging, as these feelings impact buying decisions. Multivariate analysis of variance (MANOVA) indicated that saturation had a significant effect on all the feelings that influence buying decisions. The multiple regression analysis showed that the relationships between “Attractiveness of Flesh (Att‐F)” and “Deliciousness of Flesh (Del‐F)” and the buying decision were significant. In addition, the relationship between the saturation levels set by Adobe Photoshop and Chroma difference (ΔC*ab) indicated that the appropriate Chroma difference (ΔC*ab) should be in the range of 21 to 28 to achieve the highest satisfaction and a predicted probability of buying of more than 90%.
Protective effects of quercetin against inflammation and oxidative stress in a rabbit model of knee osteoarthritis
Authors: Wei Bing , Zhang Yan , Tang Lixia , Ji Yikui , Yan Cheng , Zhang Xiaoke 
Published: January 2019

Abstract

Hit, Lead & Candidate Discovery

This study investigated the effects of a natural phenolic compound quercetin on surgical‐induced osteoarthritis (OA) in rabbits. Forty‐eight New Zealand White rabbits were used to establish OA model by Hulth modified method, and subsequently randomized into untreated OA group (treatment was drinking water), celecoxib treated group (celecoxib 100 mg kg‑1 by gavage), and quercetin treated group (25 mg kg‑1 by gavage). Sixteen nonoperated rabbits served as the normal controls (drinking water was given). The treatment (length: 4 weeks) started on the 5th week postoperation when the OA pathological changes were manifested. Expressions of superoxide dismutase (SOD), matrix metalloproteinase‐13 (MMP‐13) and tissue inhibitor of metalloproteinases‐1 (TIMP‐1) in serum, synovial fluid, and synovial tissue were measured at 8 and 12 weeks postoperation. Pathological analysis was performed with synovial tissue section and Osteoarthritis Research Society International histopathology grading and staging scores were determined. The quercetin treated group showed higher SOD and TIMP‐1 expressions but lower MMP‐13 expression than untreated OA group in the serum, synovial fluid and synovial tissues (p < .05). There was no significant difference in the SOD, MMP‐13 and TIMP‐1 expressions between the quercetin‐treated and celecoxib‐treated groups. The MMP‐13/TIMP‐1 ratio of the quercetin treated group was significantly lower than that of the untreated OA group (p < .05). Quercetin can up‐regulate SOD and TIMP‐1, down‐regulate MMP‐13, and improve the degeneration of OA through weakening the oxidative stress responses and inhibiting the degradation of cartilage extracellular matrix.
Evaluation of characteristics in VOx microbolometer fabricated by MOD on Si3N4/SiO2 membrane
Authors: Maeda Kohei , Hai Van Nhu , Nishioka Kunio , Matsutani Akihiro , Tachiki Takashi , Uchida Takashi 
Published: January 2019

AbstractVOx thin films were fabricated on Si3N4/SiO2/Si substrates by firing precursor films, which were fabricated by metal‐organic decomposition (MOD), with a reduced pressure. Resistance‐temperature (R‐T) characteristics of the films indicating the phase transition from metal to insulator with about 4 orders of resistance change specified with VO2 (M) were obtained. Furthermore, the films fabricated with a firing temperature of 580‐600°C had temperature coefficient of resistance (TCR) of −2.8 to −2.9 %/K at room temperature. After fabricating VOx microbolometers with 40 × 10 μm2 using the films on Si3N4/SiO2/Si substrates, Si with a thickness of about 340 μm was etched using Deep‐RIE and XeF2 vapor etching from the backside of the substrate. Then, the VOx microbolometer was completed on Si3N4/SiO2 membrane. The VOx microbolometer on Si3N4/SiO2 membrane had a high DC sensitivity of 2310 W−1, which was about 15 times higher than that of the microbolometer on the Si3N4/SiO2/Si substrate.
Group effects of a non‐native plant invasion on rodent abundance
Authors: Kluever Bryan M. , Smith Trinity N. , Gese Eric M. 
Published: January 2019

AbstractCheatgrass (Bromus tectorum) is the most prolific invading plant in western North America. Investigations determining the impact of this invasion on population state variables and community dynamics of rodents have largely occurred at the community or species level, creating a knowledge gap as to whether rodents affiliated by a shared taxonomy or other grouping are differentially affected by cheatgrass invasion. We examined rodent abundance along a gradient of cheatgrass cover using various groupings of two nocturnal rodent taxa comprising the majority of the rodent community in the Great Basin Desert. In the summers of 2010–2013, rodents were sampled and vegetation was measured on the U.S. Army Dugway Proving Ground in the Great Basin Desert of Utah, USA. We separately examined estimates of rodent abundance for all combined species within the Cricetidae and Heteromyidae families, the most numerically dominant species, and uncommon species pooled in relation to cheatgrass invasion severity. We detected an expected negative linear relationship between invasion severity and abundance for all cricetid groupings, including the most numerically dominant species, the deer mouse (Peromyscus maniculatus). Unexpectedly, heteromyid abundance exhibited an initial positive relationship, reached a threshold, and then exhibited a negative relationship, a phenomenon driven by Ord's kangaroo rats (Dipodomys ordii), the most numerically dominant species. We speculate this non‐linear finding was caused by a combination of trophic and non‐trophic pathways. Our findings provide new insight as to the potential for differential effects of cheatgrass on rodents in arid portions of the western United States. We suggest that future investigations on cheatgrass, and plant invader effects in general, consider parsing animal communities of interest by various taxonomic and/or ecological groupings rather than focusing exclusively on individual species or entire communities.