bluuebunny/crossref_metadata_2025_split huggingface dataset:
Volume Management in Pulmonary Arterial Hypertension Patients: An Expert Pulmonary Hypertension Clinician Perspective
Authors: Hansen Lillian , Burks Marsha , Kingman Martha , Stewart Traci 
Published: April 2018

AbstractFluid volume management in patients with pulmonary arterial hypertension (PAH) is essential in preventing right ventricular failure. Volume overload may be caused by disease progression, indiscretion of dietary sodium and fluid intake, or medication side effects, and is a frequent complication in patients with PAH. Healthcare professionals (HCPs) who care for patients with PAH have a key role in monitoring, preventing, and managing volume overload. Volume management techniques in patients with PAH include managing diuretic use and electrolyte imbalances, and monitoring fluid retention that can occur from the use of endothelin receptor antagonists or calcium channel blockers. Healthcare providers can create volume management protocols as well as patient educational materials. Patients should be educated to self-monitor their daily weights, incorporate dietary restrictions, and recognize symptoms associated with volume overload. Tools to help HCPs with volume management in patients with PAH are provided in this article.Funding Actelion Pharmaceuticals US, Inc.
Hormone Levels and Sexual Functioning After Risk-Reducing Salpingo-Oophorectomy
Authors: Johansen Nora , Liavaag Astrid H. , Mørkrid Lars , Michelsen Trond M. 
Published: April 2018

Abstract

Introduction
Women after risk-reducing salpingo-oophorectomy (RRSO) can have impaired sexual functioning, but whether there is an association between hormone levels and sexual functioning is unclear.

Aim
To determine whether hormone levels are associated with sexual functioning in women after RRSO.

Methods
This is a retrospective cohort study of 198 sexually active and 91 inactive women after RRSO. Participants completed the Sexual Activity Questionnaire, questionnaires concerning hormone replacement therapy (HRT), quality of life, care from partner, body image, and comorbidity and provided blood samples. Associations between sexual functioning scores and covariates were examined by linear regression. Variables associated with sexual activity were examined by logistic regression.

Main Outcome Measures
Associations with sexual pleasure and sexual discomfort scores were expressed by multivariable regression coefficients and associations with sexual activity were expressed by odds ratios.

Results
None of the hormone levels were associated with sexual pleasure in contrast to age (P = .032), current use of systemic HRT (P = .002), and more care form partner (P &lt; .001). Increased free androgen index (P = .016), more care from partner (P = .017), systemic HRT (P = .002), and no history of cardiovascular disease (P = .001) were associated with less sexual discomfort. The odds ratio of being sexually active increased with younger age, no breast cancer, better quality of life, and more care from partner.

Conclusions
Our results indicate that other factors than hormone levels are important for sexual functioning, although systemic HRT can have a positive impact on sexual functioning in women who have undergone RRSO. Testosterone therapy could improve women's sexual functioning after RRSO; however, the inverse association between free androgen levels and sexual discomfort should be addressed in future studies.
Comparison of Correlated Comorbidities in Male and Female Sexual Dysfunction: Findings From the Third National Survey of Sexual Attitudes and Lifestyles (Natsal-3)
Authors: Polland Allison , Davis Meghan , Zeymo Alexander , Venkatesan Krishnan 
Published: April 2018

Abstract

Background
Many of the same mechanisms involved in the sexual arousal-response system in men exist in women and can be affected by underlying general medical conditions.

Aim
To assess whether sexual function in men and women is correlated with similar comorbidities.

Methods
This study was a secondary analysis of the 3rd National Survey of Sexual Attitudes and Lifestyles (Natsal-3), a prospective stratified probability sample of British individuals 16 to 74 years old interviewed from 2010 to 2012. We assessed for an association between sexual function and the following comorbidities: heart attack, heart disease, hypertension, stroke, diabetes, chronic lung disease, depression, other mental health conditions, other neurologic conditions, obesity, menopause, incontinence, smoking status, and age.

Outcome
An association was found between multiple medical comorbidities and sexual dysfunction in women and in men.

Results
6,711 women and 4,872 men responded to the survey, were in a relationship, and reported sexual activity in the past year. The average age of the women was 35.4 ± 14.1 and that of the men was 36.8 ± 15.6. There was an association between sexual function and all variables assessed except for chronic lung disease, heart attack, and incontinence in women compared with stroke, other neurologic conditions, incontinence, and smoking status in men. Comorbidities associated with erectile dysfunction included depression, diabetes, and other heart disease, whereas comorbidities associated with difficulty with lubrication included depression and other heart disease. Menopause was predictive of sexual dysfunction. Male sexual function appeared to decline after 45.5 years of age.

Clinical Implications
Physicians should be aware of the correlation between medical comorbidities and sexual dysfunction in women and men and should ask patients about specific symptoms that might be associated with underlying medical conditions.

Strengths and Limitations
Use of a stratified probability sample compared with a convenience sample results in capturing of associations representative of the population. Inclusion of multiple comorbidities in the multivariate analysis allows us to understand the effects of several variables on sexual function. Although this study shows only an association, further research could determine whether there is a causal relation between comorbidities and sexual dysfunction in women.

Conclusion
Multiple medical comorbidities are associated with sexual dysfunction not only in men but also in women.
Nursing Home Physicians Discuss Caring for Elderly Residents: An Exploratory Study
Authors: Banerjee Albert , James Robert , McGregor Margaret , Lexchin Joel 
Published: April 2018

RÉSUMÉMalgré la complexité croissante des soins en foyers de soins de longue durée, le rôle des médecins dans la prestation des soins aux résidents a été peu étudié. Cette étude exploratoire internationale visait à mieux comprendre les rôles des médecins, leurs responsabilités et leurs tâches, ainsi qu’à explorer les caractéristiques uniques de la pratique médicale dans les foyers de soins de longue durée. Des entrevues ont été menées avec 18 médecins. Ces médecins ont mentionné qu’ils contribuaient fortement à la qualité des soins pour les résidents, en clarifiant les objectifs des soins, en prenant des mesures pour réduire les hospitalisations et les prescriptions de médicaments non nécessaires, et en contribuant à la formation du personnel. Les pratiques en foyers de soins de longue durée impliquaient les médecins au centre de réseaux de relations qui assuraient non seulement une meilleure qualité des soins médicaux, mais aussi une satisfaction professionnelle chez les médecins. L’importance de ces relations est telle qu’elle permettait d’aller au-delà des démarcations traditionnelles entre le domaine médical et le domaine social, et mettait en évidence qu’une bonne pratique médicale implique de bonnes pratiques sociales. Considérant la nature exploratoire de l’étude, les auteurs recommandent que de futures recherches soient menées pour mieux comprendre les dimensions relationnelles associées à la pratique de la médecine en foyers de soins de longue durée.
FromThere's Magic in MusictoThe Hard-Boiled Canary: Promoting “Good Music” in Prewar Musical Films
Authors: BOMBOLA GINA 
Published: April 2018

AbstractIn 1941, Paramount releasedThere's Magic in Music, a film about a soprano who sings opera in burlesque and wins a scholarship to attend Interlochen. The movie's utopian view of art music, however, caused difficulties for the studio in regard to marketing, leading to a studio-wide debate over the film's title. Archival documents positionThere's Magic in Musicas a valuable case study for investigating the transitional period of musical film production between the Great Depression and the onset of World War II, particularly with respect to operatic musicals. Just prior to the United States’ entry into the war, Hollywood moved away from the escapist fantasy of 1930s cinema toward the realism that would mark the 1940s. To reboot fading interest in musicals, studios toyed with the formula of the backstage musical to focus more on dramatic narratives and star power.There's Magic in Musicthus serves as a lens through which we might examine changes both in musical film production and in notions of “good music” at the eve of World War II.
Long‐Term Climate Simulations Using the IITM Earth System Model (IITM‐ESMv2) With Focus on the South Asian Monsoon
Authors: Swapna P. , Krishnan R. , Sandeep N. , Prajeesh A. G. , Ayantika D. C. , Manmeet S. , Vellore R. 
Published: April 2018

AbstractLong‐term climate simulations are performed using the IITM Earth System Model version 2 (IITM‐ESMv2), a sequel to the earlier version (IITM‐ESMv1), to assess climate variability and change with a special focus on the South Asian monsoon. Substantial improvements are incorporated in IITM‐ESMv2 to obtain a radiatively balanced global climate modeling framework. The IITM‐ESMv2 includes time‐varying aerosol forcing and land‐use land‐cover changes. Multicentury simulations corresponding to preindustrial and present‐day conditions show major improvements in capturing key aspects of time‐mean atmosphere and ocean large‐scale circulation. Representations of the Atlantic Meridional Overturning Circulation and poleward ocean heat transport, and major global climate drivers are superior to ESMv1. Teleconnections of the South Asian monsoon with climate drivers such as the El‐Niño–Southern Oscillation (ENSO) and the Indian Ocean Dipole (IOD) are found to be more robust in IITM‐ESMv2, thus leading to improved simulation of South Asian monsoon and its variability. The IITM‐ESMv2 takes a novel pursuit from India to contribute in the Intergovernmental Panel for Climate Change (IPCC) sixth assessment report (AR6).
Analytical modeling of hyperthermia using magnetic nanoparticles
Authors: Bensenane Mohamed Nassim , Senoudi Assia Rachida , Benmouna Reda , Ould-Kaddour Fouzia 
Published: April 2018

Hyperthermia using magnetic nanoparticles (MNPs) is one of many techniques to treat cancer causing minimal damage to healthy tissues. In the present work we give an analytical resolution of the bio-heat equation (based on Pennes model) providing the temperature rise as a function of the characteristics of the magnetic nanoparticles, the applied magnetic field and the biological properties of the tissue. The temperature inside the tumor was found to be very sensitive to the frequencyfof alternating magnetic field, magnetic field amplitudeH0and volume fractionφ. This study optimizes the intensity of magnetic field to reach ideal hyperthermia conditions. Whenfvaries between 50 and 150 KHz, temperature increases from 39 °C until 53 °C; whenH0is ranged from 5 − 15 kA/m, it increases from 39.5 °C until 49 °C, and when volume fractionφof MNPs is ranged from 2 × 10−4to 3 × 10−4it increases from 44 °C until 48 °C.
Updates on MR-Guided Focused Ultrasound for Symptomatic Uterine Fibroids
Authors: Kohi Maureen , Sridhar Divya 
Published: April 2018

AbstractMagnetic-resonance–guided focused ultrasound (MRgFUS), also called high-intensity focused ultrasound (HIFU) is an effective, noninvasive uterine-preserving treatment for symptomatic uterine fibroids. As the use of this therapeutic modality is not yet widespread, it may remain unfamiliar to many interventional radiologists. The purpose of this review is to discuss MRgFUS, including technology, patient selection, technique, outcomes, complications, and recent data on fertility and comparative effectiveness.
Updates on Uterine Artery Embolization
Authors: Spies James , Kohi Maureen 
Published: April 2018

AbstractUterine fibroids (leiomyomas) are the most common benign neoplasm of the female pelvis and have a lifetime prevalence exceeding 80% among African American women and approaching 70% among Caucasian women. Approximately 50% of women with fibroids experience symptoms which may include menorrhagia that may result in anemia, bulk symptoms with bladder and bowel dysfunction and abdominal protrusion, dysmenorrhea, and infertility. Hysterectomy remains the most common treatment option for fibroids and concerns have been raised about the overuse of this procedure. Uterine artery embolization (UAE) is now a well-established uterine preserving and minimally invasive therapy for symptomatic fibroids. Since its introduction, strong evidence for safety and efficacy of UAE has been generated with low rates of complications. This review will discuss UAE for the management of symptomatic uterine fibroids with special focus on emerging technical approaches and novel periprocedural patient care.
A note on volitional and non-volitional prefixes in Gyalrong languages
Authors: Jacques Guillaume 
Published: April 2018

Abstract
This paper addresses Prins’ (2016) recent proposal of a m(ə)‑ non-volitional prefix
in the Kyomkyo dialect of Situ, showing that alternative analyses are preferable. In addition, it offers an account of some irregular
anticausative forms in Situ, and presents evidence for a possible volitional mə‑ prefix in Gyalrong languages.1
Phonetic distance and dialect clustering on the Qinghai-Tibet plateau
Authors: Powell Abe , Suzuki Hiroyuki 
Published: April 2018

Abstract
The goal of this paper is to use string edit distance to describe the synchronic relationship between the Tibetan speech varieties located on the Northeastern edge of the Tibetan Plateau. String edit distance provides a statistical way to compare a large number of linguistic features, in essence producing a statistical bundle of isoglosses. In this way, it can be used as a tool in dialect mapping and synchronic clustering. In this paper, the aggregate distance matrix produced by string edit distance reveals that the great degree of phonetic continuity on the grasslands of the northeastern edge of the plateau is matched by an equal degree of phonetic discontinuity in the mountains forming the eastern border of the plateau. While the dialects located on the grasslands can be grouped together into one cluster, the dialects in the mountains can be grouped together into six clusters.
Ideophones in Khaling Rai
Authors: Lahaussois Aimeé 
Published: April 2018

Abstract
In Khaling Rai, a number of lexemes have been found which can be considered ideophones, according to Dingemanse’s (2012: 654) definition of the latter as “marked words depictive of sensory imagery.” This
article will describe the different types of ideophones found in Khaling. These ideophones not only manifest a range of different
morphological patterns, they cover the entire spectrum of sensory modalities found in Dingemanse’s implicational hierarchy (2012: 663), namely sound, movement, visual patterns, other sensory perceptions (such as
texture and taste) and cognitive states. The more than 400 ideophones collected to date in Khaling present a sound symbolic
landscape which appears to be considerably richer than that found in other Kiranti languages with which the author is
familiar.
Neuroprotective effect of Citrus kawachiensis (Kawachi Bankan) peels, a rich source of naringin, against global cerebral ischemia/reperfusion injury in mice
Authors: Okuyama Satoshi , Yamamoto Kana , Mori Hirotomo , Sawamoto Atsushi , Amakura Yoshiaki , Yoshimura Morio , Tamanaha Arisa , Ohkubo Yuu , Sugawara Kuniaki , Sudo Masahiko , Nakajima Mitsunari , Furukawa Yoshiko 
Published: April 2018

Abstract
Cerebral ischemia/reperfusion is known to induce the generation of reactive oxygen species and inflammatory responses. Numerous studies have demonstrated that naringin (NGIN) has anti-oxidant and anti-inflammatory properties. We previously reported that Citrus kawachiensis contains a large quantity of NGIN in its peel. In the present study, we orally (p.o.) administered dried peel powder of C. kawachiensis to mice of a transient global ischemia model and found in the hippocampus region that it 1) suppressed neuronal cell death, 2) reversed the reduction in the level of phosphorylated calcium-calmodulin-dependent protein kinase II, 3) had the tendency to reverse the reduction in the level of glutathione, and 4) blocked excessive activation of microglia and astrocytes. These results suggested that the dried peel powder of C. kawachiensis had a neuroprotective effect against ischemic brain via anti-oxidative and anti-inflammatory effects. We also showed that these effects of the dried peel powder were more powerful than those obtained with a comparable amount of NGIN alone.
Dietary astaxanthin can accumulate in the brain of rats
Authors: Manabe Yuki , Komatsu Toshiyuki , Seki Shinobu , Sugawara Tatsuya 
Published: April 2018

ABSTRACT
We evaluated the distribution of astaxanthin in rat brains after a single dose administration and after feeding 0.1% astaxanthin diet for 5 days. Astaxanthin was detected in the hippocampus and cerebral cortex 4 and 8 h after a single dose. Astaxanthin concentration in rat brains was higher after consumption of astaxanthin diet for 5 days than after a single dose.
APMP supplementary comparison (APMP.L-S8) measurement of flatness of optical flat by interferometry
Authors: Buajarern J , Bitou Y , Zi X , Zhao L , Swift N , Agarwal A , Hungwe F 
Published: April 2018

A reginal supplementary comparison, APMP.L-S8, was started in 2015 to demonstrate the equivalence of routine calibration services offered by NMIs to clients. Participants in this APMP.L-S8 comparison agreed to apply interferometric method for flatness measurement of the optical flats. There are two configurations of flatness interferometer used in this comparison, vertical type and horizontal type. There are seven laboratories from NMIs participated this supplementary comparison which included NIMT, NMIJ, NIM, NMC/A*STAR, MSL, NPLI and NMISA.
This report describes the measurement results of two optical flats, diameter of 70 mm and 160 mm. The calibrations of this comparison were carried out by participants during the period from July 2015 to September 2016. The results show that there is a degree of equivalence below 1 for all measurands. Hence, there is a close agreement between the measurements from all participants.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCL, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
Final report, on-going key comparison BIPM.QM-K1, ozone at ambient level, comparison with INECC, September 2017
Authors: Viallon Joële , Idrees Faraz , Moussay Philippe , Wielgosz Robert , Fentanes Oscar , Benítez Ángeles , Ordoñez Daniel 
Published: April 2018

As part of the ongoing key comparison BIPM.QM-K1, a comparison has been performed between the ozone national standard of Mexico maintained by the National Institute of Ecology and Climate Change (INECC) and the common reference standard of the key comparison, maintained by the Bureau International des Poids et Mesures (BIPM). The instruments have been compared over a nominal ozone amount-of-substance fraction range from 0 nmol/mol to 500 nmol/mol.

Main text

To reach the main text of this paper, click on Final Report. Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/.
The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).
From Hope to Defensiveness: The Foreign Policy of a Beleaguered Liberal Spain, 1820–1823
Authors: Butrón Prida Gonzalo 
Published: April 2018

Abstract
In 1820, the reinstatement of the Constitution of 1812 placed Spain at the head of the international political agenda, since it presented the first challenge to the status quo defined at the Congress of Vienna. During the following years, the great powers increased the pressure exerted on Spain’s Liberal regime, shifting from diplomatic pressure to the eventual French military intervention in 1823, which ruined hopes of a liberal political efflorescence in Europe. The object of this article is to systematise knowledge about Spain’s foreign policy during the so-called Liberal Triennium (1820–23), and to analyse its progress from an initial idealism, associated with prevailing Romanticism, to ultimate isolationism. This was a result of a lack of resources and also of inconsistency in Spain’s foreign policy, at a time when a well-defined international plan might have changed the fate of Spanish Liberalism. The article also pays special attention to the diplomatic relations between Spain and Great Britain, the only great power that did not pursue the marked hostility towards Spanish Liberalism displayed by the continental powers after 1820. Accordingly, most of the hopes of an increasingly besieged Liberal Spain were placed on Britain’s good offices and support.
When Adults Don’t Exercise: Behavioral Strategies to Increase Physical Activity in Sedentary Middle-Aged and Older Adults
Authors: Lachman Margie E , Lipsitz Lewis , Lubben James , Castaneda-Sceppa Carmen , Jette Alan M 
Published: April 2018

Abstract
Physical activity is one of the most promising nonpharmacological, noninvasive, and cost-effective methods of health-promotion, yet statistics show that only a small percentage of middle-aged and older adults engage in the recommended amount of regular exercise. This state of affairs is less likely due to a lack of knowledge about the benefits of exercise than to failures of motivation and self-regulatory mechanisms. Many types of intervention programs target exercise in later life, but they typically do not achieve sustained behavior change, and there has been very little increase in the exercise rate in the population over the last decade. The goal of this paper is to consider the use of effective low-cost motivational and behavioral strategies for increasing physical activity, which could have far-reaching benefits at the individual and population levels. We present a multicomponent framework to guide development of behavior change interventions to increase and maintain physical activity among sedentary adults and others at risk for health problems. This involves a personalized approach to motivation and behavior change, which includes social support, goal setting, and positive affect coupled with cognitive restructuring of negative and self-defeating attitudes and misconceptions. These strategies can lead to increases in exercise self-efficacy and control beliefs as well as self- management skills such as self-regulation and action planning, which in turn are expected to lead to long-term increases in activity. These changes in activity frequency and intensity can ultimately lead to improvements in physical and psychological well-being among middle-aged and older adults, including those from underserved, vulnerable populations. Even a modest increase in physical activity can have a significant impact on health and quality of life. Recommendations for future interventions include a focus on ways to achieve personalized approaches, broad outreach, and maintenance of behavior changes.