bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Epigenetic Signature in Adipose Tissue Is Linked to Nicotinamide N‐Methyltransferase Gene Expression
Authors: Crujeiras Ana B. , Pissios Pavlos , Moreno‐Navarrete Jose M. , Diaz‐Lagares Angel , Sandoval Juan , Gomez Antonio , Ricart Wilfredo , Esteller Manel , Casanueva Felipe F. , Fernandez‐Real Jose M. 
Published: April 2018

ScopeThe enzyme nicotinamide N‐methyltransferase (NNMT) is a major methyltransferase in adipose tissue. We hypothesized an epigenetic signature in association with NNMT gene expression in adipose tissue.Methods and resultsThe global human methylome was analyzed in visceral adipose tissue (VAT) from morbidly obese patients using the Infinium Human Methylation 450 BeadChip array (discovery cohort: n = 11). The findings were confirmed in two additional independent cohorts (cohort 1: n = 60; BMI 20–60 kg m−2 and cohort 2: n = 40; BMI > 40 kg m−2) and validated after weight loss (using microarray data). Among the genes associated with the largest methylation fold change were genes related to metabolic processes, proliferation, inflammation, and extracellular matrix remodeling, such as COL23A1, PLEC1, FBXO21, STEAP3, RGS12, IGDCC3, FOXK2, and ORAI2. In fact, the results showed 577 differentially methylated CpG sites (DMCpGs) associated with the NNMT expression levels, with low methylation levels paralleling high NNMT expression. The expression of FBXO21 and FOXK2 was specifically modified after weight loss concomitantly with a decrease in NNMT expression and inflammation‐related genes. Interestingly, the adipose tissue NNMT gene expression correlated with markers of adipose tissue inflammation.ConclusionsThe expression of NNMT in VAT is associated with a specific methylome signature involving genes linked to adipose tissue metabolic pathophysiology.
Design of a textile antenna with artificial magnetic conductor for wearable applications
Authors: Mersani Ameni , Lotfi Osman , Ribero Jean‐Marc 
Published: April 2018

AbstractWith the development of modern wireless technologies and the miniaturization of antennas and electrical systems, the use of antennas on the human body for Wi‐Fi applications has become important. However, integrating the antenna near the body immediately raises the question about the protection of the body and the radiation effectiveness of the antenna. One solution that has recently attracted great attention is the use of high impedance surfaces (HIS), which is studied here for the antennas integrated on clothes. Indeed, the HIS greatly reduces the radiation back face of the antenna, thus reducing the value of the specific absorption rate in the presence of the body. In this article, we present a dual‐band antenna placed above an artificial magnetic conductor (AMC). The AMC used has the smallest dimensions and makes it possible to obtain the behavior of a perfect magnetic conductor at 2.45 and 5.8 GHz.
A multiband dual‐standard MIMO antenna system based on monopoles (4G) and connected slots (5G) for future smart phones
Authors: Ikram M. , Sharawi M. S. , Shamim A. , Sebak A. 
Published: April 2018

AbstractIn this work, a 4G/5G multiple‐input multiple‐output (MIMO) antenna system is presented for smart phone applications. The 4G antenna operates from 1900 to 3212 MHz and 3517 to 3712 MHz with 1312 (69%) and 195 (5.5%) MHz measured bandwidths, respectively. The 5G antenna covers 25.7–30.50 GHz band with 4.8 GHz (18.7%) measured bandwidth. The 4G MIMO antenna system is based on 4‐element wideband monopoles, while the 5G one is based on 2‐element linear connected arrays (LCA). Four slots are etched to improve the isolation between the 4G MIMO antenna elements and then a 4 × 1 power divider/combiner is used to excite two of these slots to act as a LCA at mm‐waves. The concept of dual function ground slots is very useful to implement 4G and 5G MIMO antenna systems on the single substrate. The proposed design is fabricated on RO4350B substrate with a height of 0.76 mm and dielectric constant of 3.5. The overall size of the substrate is 115 × 65 × 0.76 mm3. The integrated wideband 4G/5G antenna system is a compact, low profile, and suitable for future smart phone applications. Isolation obtained was at least 15 dB and the envelope correlation coefficient (ECC) values did not exceed 0.16 between all elements.
Self‐interference cancellations for full‐duplex RF front‐end using a broadband phase‐slope adjuster
Authors: You Fei , Chen Guoqiang 
Published: April 2018

AbstractWith improved wide‐band performances compared to classical RF signal cancellation circuits, an alternate self‐interference cancellation method is presented for a full‐duplex front‐end involving a phase‐slope adjuster. This solution can adapt frequency‐dependent phase mismatch in the cancellation path. This adjuster consists of a hybrid coupler and two varactor diodes, which can expand a single cancellation sweet spot to a continuous frequency range because of a newly introduced fine phase slope tuning capability. From measurement results, a single‐loop demo circuit can suppress interferences by 42 and 32 dB in 20 and 60 MHz bandwidth, respectively.
Compact planar multiband MIMO antenna based on composite right/left‐handed transmission line for mobile phone applications
Authors: Luo Xin‐Shuai , Weng Zi‐bin , Zhang Wei‐Jun , Yang Lei 
Published: April 2018

AbstractA novel compact planar multiband multiple‐input multiple‐out (MIMO) antenna based on composite right/left handed transmission line (CRLH‐TL) for mobile phone applications is presented in this article. The proposed MIMO antenna consists of two asymmetric antenna elements and two‐sided shorted ground, which is designed by zeroth‐order resonant theory to achieve compact performance. The proposed antenna elements cover the communication bands in 698–960 MHz and 1710–2690 MHz with the planar size of 16 × 56 mm2 and 12 × 56 mm2, respectively. Acceptable agreement between simulated and experimental results over the desired operating bands is observed. The envelop correlation coefficients are calculated by the S parameters.
A novel four‐port high isolation MIMO antenna design for high‐capacity wireless applications
Authors: Liu Yu , Liu Ming , Xu Fang , Xu Jie , Huang Xiangdong 
Published: April 2018

AbstractA novel four‐port multiple‐input‐multiple‐output (MIMO) antenna with high isolation is proposed in this article. This antenna is fabricated on a FR4 substrate with a compact size of 84 mm × 26 mm × 1.6 mm (0.98λ × 0.3λ × 0.019λ, λ is the wavelength at 3.5 GHz). The design adopts curved slot‐lines on both sides of the substrate to enhance the isolation level and radiation in the working bands. The measured results show that the fabricated prototype can cover the working bands of advanced TD‐LTE, WiLAN/WiFi, and cognitive radio applications with good radiation pattern characteristics. Furthermore, the isolation among multiple ports exceeds 15, 28, and 16 dB in the three working bands respectively, and high channel capacities could be achieved by this four‐port design.
Design of wideband LTCCBPF with notch band exploiting one‐third isosceles triangular resonator
Authors: Xiangjun Zhang , Zhang Hao , Chen Yiming 
Published: April 2018

AbstractThe design of a novel multilayer wideband bandpass filter with one notch band is presented in this letter. The proposed filter structure is composed of one‐third isosceles triangular substrate integrated waveguide (SIW) cavities and the coupled striplines. The SIW cavities structure generates multiple resonant modes which are used to realize the wideband bandpass filter. Owing to the low temperature co‐fired ceramic technology, the stripline and the SIW cavity are printed on multilayer ceramic, which makes the filter compact. The filter have a compact volume of 6.0 × 8.0 × 0.4 mm3. The measured results exhibit the bandpass filter achieves a center frequency of 15 GHz with a 3 dB fractional bandwidth of 33.33% and more than 15 dB attenuation at skirt band. The width of the notch band was about 600 MHz centered at 15.5 GHz. The measured results of fabricated filter are in close agreement with the simulated ones.
Design and development of UWB (3.0–42.8 GHz) truncated annular microstrip monopole antenna
Authors: Singh R. K. , Pujara Dhaval 
Published: April 2018

AbstractA novel truncated annular microstrip monopole antenna with partial ground for ultra‐wideband (UWB) applications is designed and fabricated. Proposed antenna consists of overlapping a circular patch with truncated annular patch, fed by a stepped microstrip line designed on commercially available low cost FR‐4 substrate covering the UWB band from 3.0 to 42.8 GHz for return‐loss better than −10 dB. The designed antenna is very compact in size occupying 35 × 32 × 1.6 mm3. The full‐wave electromagnetic simulation software HFSS was used to estimate the return‐loss, radiation patterns, and gain of a proposed antenna. The measured results of return‐loss are also presented in this article.
Dual band omnidirectional circularly polarized antenna using EZR and MZR modes
Authors: Lee Jae‐Gon , Um Kwi Seob , Lee Jeong‐Hae 
Published: April 2018

AbstractA dual band omnidirectional circularly polarized (CP) antenna is presented based upon new concept of combining two orthogonal modes of epsilon‐zero resonance (EZR) and mu‐zero resonance (MZR) in this article. The antenna has the CP characteristic by two circularly ring‐structured double negative (DNG) transmission lines. One DNG transmission line has higher frequencies of EZR and lower frequency of MZR while the other DNG transmission line has higher frequencies of MZR and lower frequency of EZR. The EZR and MZR modes at the same frequency have a vertical and a horizontal polarization with 90° phase difference, respectively. In the EZR mode, a vertical polarization is generated like an electric monopole so that the EZR antenna radiates omnidirectionally. The MZR antenna makes a horizontal polarization by the circular ring current like a magnetic dipole loop which also radiates omnidirectionally. The analysis and design of the antenna are performed according to theory and simulation based on a dispersion diagram and E‐field distribution. Finally, the reasonable performances of the antenna such as a reflection coefficient, a CP gain, an axial ratio, and a far‐field radiation pattern are obtained in dual band.
Miniaturized switched line MEMS phase shifter
Authors: Anitha G. , Usha Kiran K. 
Published: April 2018

AbstractIn this article, we propose a novel miniaturized MEMS phase shifter which relies on the loading of meander line and Complementary split ring resonators meta‐material conception to resolve the issues of miniaturization and insertion loss in the transmission line. The proposed phase shifter purely entrenched upon the switchable delay line and a reference line design, which is inline with a metal contact series switch.The phase shifter and RF switches are built on a 50 Ω coplanar waveguide transmission line. One of the unique features of the switch is shaped with triangular to obtain good RF and mechanical characteristics in terms of return loss, isolation, insertion loss, pull in voltage, and stress profile. The result shows, that the mechanical performance of the triangular series switch has low actuation voltage of 5.67 V with a stress value of 5 MPa and the calculated switching time is 3.9 µs. The RF performance of the triangular switch showed an insertion loss of −0.2 with −20 dB of a return loss in the ON state, whereas, in the OFF state, isolation is around −26 dB at DC −20 GHz. The proposed switch was used to build the miniature phase shifter. The average values of the miniaturized 5‐bit phase shifter (11.25, 22.5°, 45°, 90°, and 180°) return loss and insertion loss is −16.68 and −1.35 dB and phase error is less than 0.57°. Overall, 30% size reduction in the miniaturized phase shifter is obtained using triangular single pole single throw switches.
Triple‐port, two‐mode based two element cylindrical dielectric resonator antenna for MIMO applications
Authors: Das Gourab , Sharma Anand , Gangwar Ravi Kumar , Sharawi Mohammad S. 
Published: April 2018

AbstractIn this letter, a triple‐port multiple‐input–multiple‐output (MIMO) cylindrical dielectric resonator based antenna (cDRA) supporting 2 simultaneous operating modes is presented. The cDRAs are excited by 3 ports supporting MIMO operation. Mode‐1 is an array mode achieved by exciting the 2 element cDRA array via a simple combiner at port‐1. Ports‐ 2 and −3 support individual element excitation via coaxial probes for mode‐2 yielding individual element MIMO operation. The isolation between ports‐1, 2, and 3 is improved by generating orthogonal modes in the cDRA via proper excitation. The isolation between ports‐2 and 3 is improved by etching 2 C‐shaped defected ground structure slits. For all the cases, the isolation between the ports exceeds 20 dB over the operating band. The presented dual‐mode 3‐port MIMO antenna covers the bands between 5.15 and 6.0 GHz.
Tailoring Uniform Copolymer Composition Distribution via Policy II RAFT Solution Copolymerization of Styrene and Butyl Acrylate
Authors: Jiang Jie , Wang Wen‐Jun , Li Bo‐Geng , Zhu Shiping 
Published: April 2018

AbstractControlled radical polymerization (CRP) is regarded as a powerful method to design various chain structures. Semibatch monomer feeding strategies in CRP are widely used for targeting the polymer products with desired copolymer composition distribution (CCD) and molecular weight distribution, which define the properties of polymer materials. In this work, the uniform CCD in reversible addition–fragmentation transfer (RAFT) solution copolymerization is targeted via model‐based semibatch Policy II. A RAFT solution copolymerization model is first developed and correlated with batch styrene (St) and butyl acrylate (BA) copolymerization experimental data. St/BA copolymers having three different uniform compositions are produced by the comonomer feeding Policy II. Heat and concentration analysis prove feasibility of the policy. Simulation results show that the uniform CCD can be achieved by both Policy II and Policy I, compared with starved feeding and constant feeding. Policy II gives higher and more steady rates than Policy I.
Controlling motion artefact levels in MR images by suspending data acquisition during periods of head motion
Authors: Castella Rémi , Arn Lionel , Dupuis Estelle , Callaghan Martina F. , Draganski Bogdan , Lutti Antoine 
Published: April 2018

PurposeHead movements are a major source of MRI artefacts. Prospective motion correction techniques significantly improve data quality, but strong motion artefacts may remain in the data. We introduce a framework to suspend data acquisition during periods of head motion over a predefined threshold.MethodsData was acquired with prospective motion correction and an external optical tracking system. A predictor of motion impact was introduced that accounts for the amplitude of the signal acquired at the time of the motion. From this predictor, a threshold was defined to trigger the suspension of data acquisition during periods of motion. The framework was tested on 5 subjects, 2 motion behaviors, and 2 head coils (20 and 64 channels).ResultsThe best improvements in data quality were obtained for a threshold value of 0, equivalent to suspending the acquisition based on head speed alone, at the cost of a long prolongation of scan time. For threshold values ∼3.5e−4, image quality was largely preserved, and prolongation of scan time was minimal. Artefacts occasionally remained with the 64‐channel head coil for all threshold values, seemingly due to head movement in the sharp sensitivity profile of this coil.ConclusionThe proposed suspension strategy is more efficient than relying on head speed alone. The threshold for suspension of data acquisition governs the tradeoff between image degradation due to motion and prolonged scan time, and can be tuned by the user according to the desired image quality and participant's tolerability.
T1 weighted fat/water separated PROPELLER acquired with dual bandwidths
Authors: Rydén Henric , Berglund Johan , Norbeck Ola , Avventi Enrico , Skare Stefan 
Published: April 2018

PurposeTo describe a fat/water separated dual receiver bandwidth (rBW) spin echo PROPELLER sequence that eliminates the dead time associated with single rBW sequences. A nonuniform noise whitening by regularization of the fat/water inverse problem is proposed, to enable dual rBW reconstructions.MethodsBipolar, flyback, and dual spin echo sequences were developed. All sequences acquire two echoes with different rBW without dead time. Chemical shift displacement was corrected by performing the fat/water separation in k‐space, prior to gridding. The proposed sequences were compared to fat saturation, and single rBW sequences, in terms of SNR and CNR efficiency, using clinically relevant acquisition parameters. The impact of motion was investigated.ResultsChemical shift correction greatly improved the image quality, especially at high resolution acquired with low rBW, and also improved motion estimates. SNR efficiency of the dual spin echo sequence was up to 20% higher than the single rBW acquisition, while CNR efficiency was 50% higher for the bipolar acquisition. Noise whitening was deemed necessary for all dual rBW acquisitions, rendering high image quality with strong and homogenous fat suppression.ConclusionDual rBW sequences eliminate the dead time present in single rBW sequences, which improves SNR efficiency. In combination with the proposed regularization, this enables highly efficient T1‐weighted PROPELLER images without chemical shift displacement.
Design of programs to train pelvic floor muscles in men with urinary dysfunction: Systematic review
Authors: Hall Leanne M. , Aljuraifani Rafeef , Hodges Paul W. 
Published: April 2018

AimsPelvic floor muscle training (PFMT) is a first line conservative treatment for men with urinary dysfunction, but reports of its efficacy are variable. This study aimed to systematically review the content of PFMT programs used for urinary dysfunction in men.MethodsElectronic databases (PubMed, CINAHL, EMBASE, Cochrane, PEDro) were searched for studies that used PFMT in the treatment of adult men with urinary dysfunction. Details of PFMT treatment sessions and home exercise protocols were extracted. Criteria specific to PFMT were developed, based on the Consensus on Exercise Reporting Template, and applied to all studies to measure the comprehensiveness of the PFMT description in the manuscript.ResultsResults from the 108 included studies indicate substantial heterogeneity in both the content of PFMT and the quality of reporting of the components of the exercise regimes. There was notable disparity in the muscles targeted by the interventions (and few focused on urethral control despite the use in management of urinary conditions) and the intensity of the programs (eg, 18‐240 contractions per day). Most studies were missing key details of description of the PFMT programs (eg, the position in which the pelvic floor muscle [PFM] contraction was taught and how it was assessed, methods used to ensure exercise adherence).ConclusionsVariation in content of PFMT programs is likely to contribute to variation in the reported efficacy for management of urinary dysfunction in men, and unclear description of the details of the evaluated programs makes it difficult to identify the effective/ineffective components. PROSPERO registration number CRD42017071038.
A quasi‐experimental study of the effect of teaching Orem's self‐care model on nursing students’ clinical performance and patient satisfaction
Authors: Malekzadeh Javad , Amouzeshi Zahra , Mazlom Seyed Reza 
Published: April 2018

AbstractAimsThis study aims to determine the effect of teaching Orem's self‐care model on nursing students’ clinical performance and patient satisfaction.DesignThe study was a quasi‐experimental, non‐randomized, two‐group design with posttest.MethodsIn this quasi‐experimental study, 66 nursing students were selected via convenience sampling method. The intervention group was trained based on Orem's self‐care model and the control group based on the routine nursing process method. Both groups cared patients for a week. Students’ performance was evaluated during the clinical course by performance observation checklist and patient satisfaction was assessed at the end of clinical course using patient satisfaction form. Data were analysed in SPSS software using chi‐squared, Fisher Exact test, Mann–Whitney, t test and two‐way ANOVA.ResultsClinical performance evaluation mean score in the intervention group was significantly higher than that of the control group. However, patient satisfaction scores in both the control group and intervention group did not show statistically significant differences. Orem's self‐care model showed a 23% improvement in students’ performance. It is recommended to use Orem's self‐care model for undergraduate courses, especially in clinical training.
Weight Stigma in Men: What, When, and by Whom?
Authors: Himmelstein Mary S. , Puhl Rebecca M. , Quinn Diane M. 
Published: April 2018

ObjectiveThis study assessed the weight stigma experiences of men, examining characteristics of men who experienced weight stigma versus men who did not.MethodsData from three samples of men were examined (N = 1,513). Sample 1 consisted of men with obesity at elevated risk for weight stigma. Sample 2 comprised a convenience online panel. Sample 3 included men from a national online panel of US adults. Men in all samples completed almost identical questionnaires assessing demographics, anthropometrics, weight stigma, and dieting.ResultsApproximately 40% of men reported experiencing weight stigma. Weight stigma was associated with increased odds of having a BMI consistent with underweight or obesity relative to normal weight. Verbal mistreatment was the most common form of weight stigma experienced across all life stages for men. The most common sources of weight stigma were peers, family members, and strangers. Men reporting weight stigma were younger and less likely to be married, had higher BMIs, and were more likely to have tried to lose weight in the past year relative to men not reporting weight stigma.ConclusionsUnderstanding differences among men as a function of weight stigma is important for practitioners, as it can identify men who may most benefit from intervention.
Neural Food Reward Processing in Successful and Unsuccessful Weight Maintenance
Authors: Simon Joe J. , Becker Alexandra , Sinno Maria Hamze , Skunde Mandy , Bendszus Martin , Preissl Hubert , Enck Paul , Herzog Wolfgang , Friederich Hans‐Christoph 
Published: April 2018

ObjectiveWeight loss maintenance is one of the biggest challenges in behavioral weight loss programs. The present study aimed to examine metabolic influences on the mesolimbic reward system in people with successful and unsuccessful long‐term weight loss maintenance.MethodsThirty‐three women with obesity at least 6 months after the completion of a diet were recruited: seventeen women were able to maintain their weight loss, whereas sixteen showed weight regain. Using functional magnetic resonance imaging in combination with the assessment of appetite‐regulating hormones, neural reward processing during hunger and satiety was investigated. An incentive delay task was employed to investigate the expectation and receipt of both food‐related and monetary reward.ResultsOnly participants with successful weight loss maintenance showed a satiety‐induced attenuation of brain activation during the receipt of a food‐related reward. Furthermore, in successful weight loss maintenance, the attenuation of active ghrelin levels was related to brain activation in response to food‐related reward anticipation during satiety.ConclusionsThe findings suggest that an attenuated influence of satiety signaling on the neural processing of food‐related reward contributes to unsuccessful weight loss maintenance. Thus, intact satiety signaling to the mesolimbic reward system may serve as a promising target for tackling weight cycling.