bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing rotor plane induction determined from full‐scale measurements and CFD simulations
Authors: Ghadirian Amin , Larsen Gunner Chr. , Troldborg Niels 
Published: September 2018

AbstractThis paper investigates the flow field in the rotor plane of a full‐scale operating wind turbine using full‐scale light detection and ranging (LiDAR) measurements for the first time. Comparison of the measured flow field with results from large eddy simulations (LES) combined with an actuator line approach is also presented for in‐depth study of the induction field in the rotor plane. The measurements include data from two synchronized LiDAR systems—one scanning the undisturbed upstream inflow field and one measuring in the rotor plane. The standard deviation of the mean of velocity time series are and presented as a measure of reliability. The method for calculating the axial velocity based on the line‐of‐sight velocity is explained and the uncertainty of such method is presented. The process of calculating the yaw misalignment is described.The time‐averaged and phase‐averaged axial velocity and induction factors are presented relative to radius and azimuth, and the general behavior is described relative to the flow regimes around the blades, tower and nacelle. Simulations and measurements are compared with special emphasis on the flow structures in the vicinity of the individual rotor blades. A convincing agreement between measurements and simulations is demonstrated. The uncertainties originated from the imprecise positions and angles of the measurement instruments are shown. The uncertainties are limited to the middle parts of the blades between 15 m to 25 m from the root. In addition, longer selected time series show smaller uncertainties. This proves the reliability of the application of the methodology for even longer time series.
Survey of neural network‐based models for short‐term traffic state prediction
Authors: Do Loan N. N. , Taherifar Neda , Vu Hai L. 
Published: September 2018

Traffic state prediction is a key component in intelligent transport systems (ITS) and has attracted much attention over the last few decades. Advances in computational power and availability of a large amount of data have paved the way to employ advanced neural network (NN) models for ITS, including deep architectures. There have been various NN‐based approaches proposed for short‐term traffic state prediction that are surveyed in this article, where the existing NN models are classified and their application to this area is reviewed. An in‐depth discussion is provided to demonstrate how different types of NNs have been used for different aspects of short‐term traffic state prediction. Finally, possible further research directions are suggested for additional applications of NN models, especially using deep architectures, to address the dynamic nature in complex transportation networks.This article is categorized under:

Technologies > Prediction
Technologies > Machine Learning
Application Areas > Science and Technology
Market and nonmarket valuation of North Carolina's tundra swans among hunters, wildlife watchers, and the public
Authors: Frew Kristin N. , Peterson M. Nils , Sills Erin , Moorman Christopher E. , Bondell Howard , Fuller Joseph C. , Howell Douglas L. 
Published: September 2018

ABSTRACTWildlife‐related tourism represents an important and growing economic sector for many rural communities and may be inadequately considered during regional planning. Providing robust estimates of wildlife values can help address this challenge. We used both market and nonmarket valuation methods to estimate the value of tundra swans (Cygnus columbianus) in North Carolina, USA, and compared tundra swan values among hunters, wildlife watchers, and general public. Wildlife watchers reported the greatest willingness‐to‐pay (US$35.2/wildlife watcher/yr), followed by hunters (US$30.53/hunter/yr), and residents (US$16.27/resident/yr). We used the Impact Analysis for Planning system software to estimate market values or economic activity associated with tundra swans. Tundra swan hunters spent an average of US$408.34/hunter/year. Depending on assumptions over the substitutability of tundra swan hunting, we estimate that it generates value added of between US$306,155/year and US$920,161/year for the state economy. Wildlife watchers spent an average of US$171.25/wildlife watcher/year. We estimate that this generates value added of between US$14 million/year and US$42.9 million/year for the state economy, again depending on assumptions about whether watching tundra swans would be substituted with other leisure activities in eastern North Carolina or out‐of‐state. Compared with studies of international nature tourism, we found relatively low leakage rates (i.e., loss of economic benefits outside the study region), suggesting that enhancing opportunities for hunting and wildlife‐viewing may be an effective economic development strategy for rural areas in the United States. Presenting both market and nonmarket values provides a more complete picture of the value of wildlife and may facilitate more effective management decisions; therefore, we recommend that both market and nonmarket values be considered to optimize tradeoffs between development and wildlife recreation. © 2018 The Wildlife Society.
Heavy quark jet fragmentation
Authors: Dai Lin , Kim Chul , Leibovich Adam K. 
Published: September 2018

Abstract
In this paper we study the fragmentation of a parton into a jet containing a heavy quark. When heavy quarks are involved in a jet, the quark mass can lead to a numerically significant correction to the jet cross section and its substructure. With this motivation, we calculated the heavy quark mass effects to next-to-leading order in αs on the fragmentation functions to a jet (FFJs) and the jet fragmentation functions (JFFs), where the former describes fragmentation of parton into a jet and the latter describes fragmenting processes inside a jet. The finite size of the heavy quark mass does not change the ultraviolet behaviors, but it can give significant corrections to the finite contributions. When we take the zero mass limit, we find that the FFJs and the JFFs reproduce established results for massless partons. If we define the heavy quark jet as one that include at least one heavy (anti-)quark, the tagged heavy quark jet production is sensitive to the heavy quark mass and produces large logarithms of the mass. Taking advantage of the FFJs and JFFs, we formulate a factorization theorem for heavy quark jet production in order to resum these large logarithms systematically. As an application, we study inclusive b-jet production and show phenomenological implications due to keeping a non-zero quark mass.
225Ac-PSMA-617 in chemotherapy-naive patients with advanced prostate cancer: a pilot study
Authors: Sathekge Mike , Bruchertseifer Frank , Knoesen Otto , Reyneke Florette , Lawal Ismaheel , Lengana Thabo , Davis Cindy , Mahapane Johncy , Corbett Ceceila , Vorster Mariza , Morgenstern Alfred 
Published: September 2018

Abstract

Background
A remarkable therapeutic efficacy has been demonstrated with 225Ac-prostate-specific membrane antigen (PSMA)-617 in heavily pre-treated metastatic castration-resistant prostate cancer (mCRPC) patients. We report our experience with 225Ac-PSMA-617 therapy in chemotherapy-naïve patients with advanced metastatic prostate carcinoma.

Methods
Seventeen patients with advanced prostate cancer were selected for treatment with 225Ac-PSMA-617 in 2-month intervals, with initial activity of 8 MBq, then de-escalation to 7 MBq, 6 MBq or 4 MBq in cases of good response. In one patient, activity was escalated to 13 MBq in the third cycle. Fourteen patients had three treatment cycles administered, while in three patients treatment was discontinued after two cycles due to good response. Six out of 17 patients received additional treatments after the third cycle. Prostate-specific antigen (PSA) was measured every 4 weeks for PSA response assessment. 68Ga-PSMA-PET/CT was used for functional response assessment before each subsequent treatment cycle. Serial full blood count, renal function test, and liver function were obtained to determine treatment-related side effects.

Results
Good antitumor activity assessed by serum PSA level and 68Ga-PSMA-PET/CT was seen in 16/17 patients. In 14/17 patients, PSA decline ≥90% was seen after treatment, including seven patients with undetectable serum PSA following two (2/7) or three cycles (5/7) cycles of 225Ac-PSMA-617. Fifteen of 17 patients had a > 50% decline in lesions avidity for tracer on 68Ga-PSMA-PET/CT including 11 patients with complete resolution (PET-negative and either stable sclerosis on CT for bone or resolution of lymph node metastases) of all metastatic lesions. Grade 1/2 xerostomia was seen in all patients, and none was severe enough to lead to discontinuation of treatment. One patient had with extensive bone marrow metastases and a background anemia developed a grade 3 anemia while another patient with solitary kidney and pre-treatment grade 3 renal failure developed grade 4 renal toxicity following treatment. The group presented with significant palliation of bone pain and reduced toxicity to salivary glands due to de-escalation.

Conclusions

225Ac-PSMA-617 RLT of chemotherapy-naïve patients with advanced metastatic prostate carcinoma led to a ≥ 90% decline in serum PSA in 82% of patients including 41% of patients with undetectable serum PSA who remained in remission 12 months after therapy. The remarkable therapeutic efficacy reported in this study could be achieved with reduced toxicity to salivary glands due to de-escalation of administered activities in subsequent treatment cycles. This necessitates further exploration for informing clinical practice and clinical trial design.
Laparoscopy in Rwanda: A National Assessment of Utilization, Demands, and Perceived Challenges
Authors: Robertson Faith , Mutabazi Zeta , Kyamanywa Patrick , Ntakiyiruta Georges , Musafiri Sanctus , Walker Tim , Kayibanda Emmanuel , Mukabatsinda Constance , Scott John , Costas‐Chavarri Ainhoa 
Published: September 2018

AbstractBackgroundLaparoscopy has proven to be feasible and effective at reducing surgical morbidity and mortality in low resource settings. In Rwanda, the demand for and perceived challenges to laparoscopy use remain unclear.MethodsA mixed‐methods study was performed at the four Rwandan national referral teaching hospitals. Retrospective logbook reviews (July 2014–June 2015) assessed procedure volume and staff involvement. Web‐based surveys and semi‐structured interviews investigated barriers to laparoscopy expansion.ResultsDuring the study period, 209 laparoscopic procedures were completed: 57 (27.3%) general surgery cases; 152 (72.7%) ob/gyn cases. The majority (58.9%, 125/209) occurred at the private hospital, which performed 82.6% of cholecystectomies laparoscopically (38/46). The three public hospitals, respectively, performed 25% (7/28), 15% (12/80), and 0% (denominator indeterminate) of cholecystectomies laparoscopically. Notably, the two hospitals with the highest laparoscopy volume relied on a single surgeon for more than 85% of cases. The four ob/gyn departments performed between 4 and 87 laparoscopic cases (mostly diagnostic). Survey respondents at all sites listed a dearth of trainers as the most significant barrier to performing laparoscopy (65.7%; 23/35). Other obstacles included limited access to training equipment and courses. Equipment and material costs, equipment functionality, and material supply were perceived as lesser barriers. Twenty‐two interviews revealed widespread interest in laparoscopy, insufficient laparoscopy exposure, and a need for trainers.ConclusionWhile many studies identify cost as the most prohibitive barrier to laparoscopy utilization in low resource settings, logbook review and workforce perception indicate that a paucity of trainers is currently the greatest obstacle in Rwanda.
Improved acid-stress tolerance of Lactococcus lactis NZ9000 and Escherichia coli BL21 by overexpression of the anti-acid component recT
Authors: Zhu Zhengming , Ji Xiaomei , Wu Zhimeng , Zhang Juan , Du Guocheng 
Published: September 2018

Abstract
Acid accumulation caused by carbon metabolism severely affects the fermentation performance of microbial cells. Here, different sources of the recT gene involved in homologous recombination were functionally overexpressed in Lactococcus lactis NZ9000 and Escherichia coli BL21, and their acid-stress tolerances were investigated. Our results showed that L. lactis NZ9000 (ERecT and LRecT) strains showed 1.4- and 10.4-fold higher survival rates against lactic acid (pH 4.0), respectively, and that E. coli BL21 (ERecT) showed 16.7- and 9.4-fold higher survival rates than the control strain against lactic acid (pH 3.8) for 40 and 60 min, respectively. Additionally, we found that recT overexpression in L. lactis NZ9000 improved their growth under acid-stress conditions, as well as increased salt- and ethanol-stress tolerance and intracellular ATP concentrations in L. lactis NZ9000. These findings demonstrated the efficacy of recT overexpression for enhancing acid-stress tolerance and provided a promising strategy for insertion of anti-acid components in different hosts.
Cigarette Smoking and All-Cause and Cause-Specific Adult Mortality in the United States
Authors: Lariscy Joseph T. , Hummer Robert A. , Rogers Richard G. 
Published: September 2018

AbstractThis study illuminates the association between cigarette smoking and adult mortality in the contemporary United States. Recent studies have estimated smoking-attributable mortality using indirect approaches or with sample data that are not nationally representative and that lack key confounders. We use the 1990–2011 National Health Interview Survey Linked Mortality Files to estimate relative risks of all-cause and cause-specific mortality for current and former smokers compared with never smokers. We examine causes of death established as attributable to smoking as well as additional causes that appear to be linked to smoking but have not yet been declared by the U.S. Surgeon General to be caused by smoking. Mortality risk is substantially elevated among smokers for established causes and moderately elevated for additional causes. We also decompose the mortality disadvantage among smokers by cause of death and estimate the number of smoking-attributable deaths for the U.S. adult population ages 35+, net of sociodemographic and behavioral confounders. The elevated risks translate to 481,887 excess deaths per year among current and former smokers compared with never smokers, 14 % to 15 % of which are due to the additional causes. The additional causes of death contribute to the health burden of smoking and should be considered in future studies of smoking-attributable mortality. This study demonstrates that smoking-attributable mortality must remain a top population health priority in the United States and makes several contributions to further underscore the human costs of this tragedy that has ravaged American society for more than a century.
Trends and Outcomes After Prenatal Diagnosis of Congenital Cardiac Defects: Experience of a Dedicated Fetal Medicine Centre from South India
Authors: Devadasan Shyama , Balakrishnan Bijoy , Batra Meenu , Sreeja P. S. , Patil Swapneel N. , Gopinathan K. K. 
Published: September 2018

AbstractThe primary objective of the study was to present a 5-year data on the outcomes after prenatal diagnosis of CHD. This is a retrospective descriptive study, conducted in the fetal medicine unit of an academic tertiary care referral centre in South India. The details of all cases with a prenatal diagnosis of fetal cardiac lesions from January 2012 through December 2016 were collected. All cases were systematically analyzed for type of lesion, associated malformations, chromosomal abnormalities, prognosis of the lesion, the decision taken by the couples and the information regarding post natal outcome, wherever available. Prenatally diagnosed fetal cardiac lesions were identified in 310 cases. In 220 (76.1%) cases, the couple opted for termination of pregnancy. In this group, 52% of them had an isolated cardiac defect with good prognosis. In the rest of the 69 cases who decided to continue, 7 cases had an IUD. In the 62 cases that culminated in a live birth, 46 cases opted for postnatal cardiac care. Corrective surgery was attempted in 18 neonates with 2 resulting in neonatal death. Prenatal diagnosis of isolated CHD provides an opportunity for an improved immediate neonatal outcome. A thorough evaluation for extracardiac and genetic abnormality will facilitate better utilization of health care resources by triaging patients with isolated CHD having good prognosis for targeted postnatal care. Also, antenatal pediatric cardiology counselling will enable the couple to make decisions regarding postnatal management options.
Temporal variations of cryoconite holes and cryoconite coverage on the ablation ice surface of Qaanaaq Glacier in northwest Greenland
Authors: Takeuchi Nozomu , Sakaki Ryutaro , Uetake Jun , Nagatsuka Naoko , Shimada Rigen , Niwano Masashi , Aoki Teruo 
Published: September 2018

AbstractCryoconite holes are water-filled cylindrical holes formed on ablation ice surfaces and commonly observed on glaciers worldwide. Temporal changes of cryoconite holes characteristically <5 cm in diameter were monitored with a time-lapse interval camera over 15 d during the melting season on Qaanaaq Glacier in northwest Greenland. The holes drastically changed their dimensions and synchronously collapsed twice during the study period. When the holes collapsed, the coverage of cryoconite on the ice surface increased from 1.0 to 3.5% in the field of view of the camera, and then decreased again to 0.4% after the holes reformed. Comparison with meteorological data showed that the collapses occurred in cloudy and rainy or windy weather conditions, corresponding to low shortwave solar radiation (68–126 W m−2, 40–55% of the incoming flux). In contrast, holes developed in sunny conditions correspond to high solar radiation (186–278 W m−2, 63–88%). Results suggest that the dimensions of holes drastically changed depending on the weather conditions and that frequent cloudy, warm and windy conditions would cause a decay of holes and weathering crust, inducing an increase in the cryoconite coverage on the ice, consequently darkening the glacier surface.
The impact of dynamic roughness elements on marginally separated boundary layers
Authors: Servini P. , Smith F. T. , Rothmayer A. P. 
Published: September 2018

It has been shown experimentally that dynamic roughness elements – small bumps embedded within a boundary layer, oscillating at a fixed frequency – are able to increase the angle of attack at which a laminar boundary layer will separate from the leading edge of an airfoil (Grager et al., in 6th AIAA Flow Control Conference, 2012, pp. 25–28). In this paper, we attempt to verify that such an increase is possible by considering a two-dimensional dynamic roughness element in the context of marginal separation theory, and suggest the mechanisms through which any increase may come about. We will show that a dynamic roughness element can increase the value of

$\unicode[STIX]{x1D6E4}_{c}$

as compared to the clean airfoil case;

$\unicode[STIX]{x1D6E4}_{c}$

represents, mathematically, the critical value of the parameter

$\unicode[STIX]{x1D6E4}$

below which a solution exists in the governing equations and, physically, the maximum angle of attack possible below which a laminar boundary layer will remain predominantly attached to the surface. Furthermore, we find that the dynamic roughness element impacts on the perturbation pressure gradient in two possible ways: either by decreasing the magnitude of the adverse pressure peak or by increasing the streamwise extent in which favourable pressure perturbations exist. Finally, we discover that the marginal separation bubble does not necessarily have to exist at

$\unicode[STIX]{x1D6E4}=\unicode[STIX]{x1D6E4}_{c}$

in the time-averaged flow and that full breakaway separation can therefore occur as a result of the bursting of transient bubbles existing within the length scale of marginal separation theory.
Hydrodynamic interactions between aerosol particles in the transition regime
Authors: Corson James , Mulholland G. W. , Zachariah M. R. 
Published: September 2018

We present a method for calculating the hydrodynamic interactions between particles in the kinetic (or transition regime), characterized by non-negligible particle Knudsen numbers. Such particles are often present in aerosol systems. The method is based on our extended Kirkwood–Riseman theory (Corson et al., Phys. Rev. E, vol. 95 (1), 2017c, 013103), which accounts for interactions between spheres using the velocity field around a translating sphere as a function of Knudsen number. Results for the two-sphere problem at small Knudsen numbers are in good agreement with those obtained using Felderhof’s interaction actions for mixed slip-stick boundary conditions, which are accurate to order

$r^{-7}$

(Felderhof, Physica A, vol. 89 (2), 1977, pp. 373–384). The strength of the interactions decreases with increasing Knudsen number. Results for two fractal aggregates demonstrate that one can apply a point force approach for interactions between particles in the transition regime; the interaction tensor is similar to the Oseen tensor for continuum flow. Using this point force approach, we present an analysis for the settling of an unbounded cloud of particles. Our analysis shows that for sufficiently high volume fractions and cloud radii, the cloud behaves as a gas droplet in continuum flow even when the individual particles are small relative to the mean free path of the gas. The method presented here can be applied in a Brownian dynamics simulation analogous to Stokesian dynamics to study the behaviour of a dense aerosol system.
On viscous propulsion in active transversely isotropic media
Authors: Cupples G. , Dyson R. J. , Smith D. J. 
Published: September 2018

Very low Reynolds number propulsion is a topic of enduring interest due to its importance in biological systems such as sperm migration in the female reproductive tract. Motivated by the fibrous nature of cervical mucus, several recent studies have considered the effect of anisotropic rheology; these studies have generally employed the classical swimming sheet model of G. I. Taylor. The models of Cupples et al. (J. Fluid Mech. vol. 812, 2017, pp. 501–524) and Shi & Powers (Phys. Rev. Fluids vol. 2, 2017, 123102) consider related problems which in a common limit (passive, slightly anisotropic) make different predictions regarding how swimming speed depends on alignment angle. In the present paper we find that this discrepancy is due to missing terms in the analysis of Cupples et al., and that when these terms are correctly included, the models agree in their common limit. We further explore the predictions of the corrected model for both passive and active cases; it is found that for certain combinations of alignment angle and activity parameter, propulsion is halted; in other cases the small amplitude asymptotic expansion is no longer valid, motivating future numerical study.