bluuebunny/crossref_metadata_2025_split huggingface dataset:
Handel’s choruses of ‘praise and thanksgiving after victory’ and Non nobis Domine
Authors: Kim Minji 
Published: September 2019

Abstract
Handel highlights several climactic moments in his works with choruses composed of closely related cantus firmus themes and contrapuntal settings. Parallels can be traced through individual sections of some of the key compositions that define his career in England: ‘Oh Lord, in thee have I trusted’, from the Utrecht Te Deum (1713), ‘Blessed be God’, from Let God arise (1717–18/1726), ‘I will sing’, from Israel in Egypt (1738), and ‘Hallelujah’ from Messiah (1741). The common purpose of giving thanks and praise to God for military victory further links these choruses. While several different melodic sources have been suggested for the cantus firmus subjects thus far, the affinity of all four of Handel’s themes to the incipit of a very well-known canon, Non nobis Domine, invites an exploration of its possible citation. The customary practice of singing the canon or reciting its psalm text at celebratory moments, modelling the psalmist’s deflection of all the honour of his accomplishments to God, makes its reference in Handel’s works highly appropriate. Understanding Handel’s multiple reuse of his choral setting in the context of this tradition deepens the relevance of his music as well as our perspective on his self-borrowing.
Historical microbiology – using a Van Musschenbroek microscope
Authors: Quint Koen D , Robertson Lesley A 
Published: September 2019

ABSTRACT
A single-lensed microscope made by the Van Musschenbroek workshops between 1690 and 1750 has been examined experimentally, and the method of use established. The results were compared with those obtained with facsimile van Leeuwenhoek microscopes. As might be expected, each microscope had its stronger and weaker points.
Disparities in Acute Pain Treatment by Cognitive Status in Older Adults With Hip Fracture
Authors: Chang Andrew K , Edwards Robert R , Morrison R Sean , Argoff Charles , Ata Ashar , Holt Christian , Bijur Polly E 
Published: September 2019

Abstract

Background
We examined the disparities in emergency department (ED) pain treatment based on cognitive status in older adults with an acute hip fracture.

Methods
Observational study in an academic ED in the Bronx, New York. One hundred forty-four adults aged 65 years and older with acute hip fracture were administered the Telephone Interview for Cognitive Status (TICS) while in the ED. The primary outcome was receipt of any parenteral analgesic. The risk factor of interest was cognitive impairment (TICS ≤ 25). Secondary outcomes included receipt of any opioid, receipt of any analgesic, total dose of analgesics in intravenous morphine equivalent units (MEQ), and time to receiving first analgesic.

Results
Of the 87 (60%) study patients who were cognitively impaired, 60% received a parenteral analgesic compared to 79% of the 57 cognitively unimpaired patients (RR 0.76 [95% CI 0.61, 0.94]). The effect of cognitive impairment on receiving any opioids (RR: 0.81, 95% CI 0.67, 0.98) and any analgesic (RR: 0.85; 95% CI: 0.71, 1.01) was similar. The median analgesic dose in cognitively impaired patients was significantly lower than in cognitively unimpaired patients (4 MEQ vs 8 MEQ, p = .003).

Conclusion
Among older adults presenting to the ED with acute hip fracture, cognitive impairment was independently associated with lower likelihood of receiving analgesia and lower amount of opioid analgesia.
Illuminating Meanings of Thriving for Persons Living in Nursing Homes
Authors: Baxter Rebecca , Sandman Per-Olof , Björk Sabine , Lood Qarin , Edvardsson David 
Published: September 2019

AbstractBackground and ObjectivesThriving has been described as a multidimensional concept that can be used to explore place-related well-being; however, there has been limited research into the meaning of thriving in aged care. This study aimed to illuminate meanings of thriving as narrated by persons living in nursing homes.Research Design and MethodsNarrative interviews were conducted with 21 persons residing in a rural Australian nursing home. The interviews were audio-recorded, transcribed, and interpreted using a phenomenological hermeneutic approach.ResultsMeanings of thriving could be understood as: Striving toward acceptance of being in a nursing home while maintaining a positive outlook; Feeling supported and cared for while maintaining a sense of independence; Balancing opportunities for solitude and company while living with others; and, Feeling a sense of home while residing in an institutional environment. The meanings of thriving, as presented through the interpretive lens of Gaston Bachelard’s “Poetics of Space,” encompassed having access to literal, metaphorical, and symbolic doors, as well as having the freedom to open, close, and use these doors however the person wishes.DiscussionExploring meanings of thriving in nursing homes could contribute towards understanding and implementing positive life-world constructs in research and practice. These findings could be used to inform and enhance person-centered care practices by maximizing opportunities for persons residing in nursing homes to have options and choices, and the agency to make decisions where possible, in relation to their everyday care and living environment.
Study of the quantitative effect of the depositional layering tendency of inclusions on the elastic anisotropy of shale based on two-step homogenization
Authors: Zhang Yao , Xie Lingzhi , Zhao Peng , He Bo 
Published: September 2019

SUMMARYShale anisotropy is related to numerous small-scale factors, including the transverse isotropy of clay particles, clay shape aspect ratio, shape preference orientation, pore/crack alignment, infilling materials and the depositional distribution and shape aspect ratio of inclusion minerals. Although a depositional layering tendency of inclusions due to sedimentation has been observed, few studies of its effect on shale anisotropy have been carried out. In this work, the effect of the depositional layering tendency of inclusions on the elastic anisotropy of shale is quantitatively analysed along with three other factors (i.e. the inclusion fraction, the orientation dependence of clay elastic properties, where ‘oriented’ refers to transverse isotropic clay and ‘non-oriented’ refers to isotropic clay, and the clay elastic moduli) based on analysis of variance and the two-step homogenization of shale by assuming that shale is a composite of clay and inclusions. The results show that the depositional layering tendency of inclusions of this type of shale has a relatively limited effect on the elastic anisotropy of intact shale, while the orientation dependence of the elastic properties of the clay has a predominant influence.
Utilization of Diagnostic Imaging and Ionizing Radiation Exposure—Has the Tide Already Turned?
Authors: Zundler Sebastian 
Published: September 2019

Abstract
Inflammatory bowel diseases require repetitive abdominal imaging for diagnosis, follow-up, or management of complications. This editorial comments on the large incident-based case–control study on utilization of diagnostic imaging and ionizing radiation exposure by Nguyen and colleagues published in this issue.
Utilization of pop-up satellite archival transmitting tags to evaluate thorny skate (Amblyraja radiata) discard mortality in the Gulf of Maine groundfish bottom trawl fishery
Authors: Knotek Ryan , Kneebone Jeff , Sulikowski James , Curtis Tobey , Jurek Joseph , Mandelman John 
Published: September 2019

AbstractThorny skate (Amblyraja radiata) remain one of the most overfished species in the Gulf of Maine (GOM) despite being designated as a prohibited (zero-possession, mandatory release) species by the New England Fishery Management Council in 2003. To better understand the extent to which discard mortality (DM) occurring after incidental capture in the GOM groundfish bottom trawl fishery may be impeding recovery, 75 individuals (55–94 cm total length, TL) were tagged with pop-up satellite archival transmitting (PSAT) tags and monitored for up to 28 days following capture under representative commercial trawl fishing practices. Data recovered from 61 PSAT-tagged skate were analysed with a longitudinal survival analysis to estimate DM and identify influential capture-related variables. DM rate was a function of TL, with larger skates (>70 cm; DM = 16.5%) experiencing lower mortality than smaller conspecifics (55–70 cm; DM = 24.5%). From our results, we estimate annual thorny skate DM in the GOM groundfish bottom trawl fishery to be 79.2 ± 0.2 mt, which accounts for <1% of the existing stock biomass in the GOM (8400 mt). This study confirms that thorny skate are relatively resilient to bottom trawl fishing practices in the GOM, and suggests that other sources of mortality may be impeding population recovery.
Drug Abuse-Related Neuroinflammation in Human Postmortem Brains: An Immunohistochemical Approach
Authors: Moretti Matteo , Belli Giacomo , Morini Luca , Monti Maria Cristina , Osculati Antonio Marco Maria , Visonà Silvia Damiana 
Published: September 2019

Abstract
The aim of the study was to investigate blood-brain barrier alterations, neuroinflammation, and glial responses in drug abusers. Five immunohistochemical markers (CD3, zonula occludens-1 [ZO-1], intracellular adhesion molecule 1 [ICAM-1], vascular cell adhesion molecule [VCAM-1], and glial fibrillary acidic protein [GFAP]) were assessed on postmortem brain samples collected from drug abusers who died from acute intoxication of cocaine, heroin, or a combination of both, compared with controls. CD3 and ICAM-1 immunopositivity were significantly stronger in drug abusers than in controls. VCAM-1 immunopositivity was similar across drug abuser and control groups. In heroin abusers, significantly lower ZO-1 immunopositivity was observed relative to controls. GFAP positivity did not show significant differences between groups, but its distribution within the brain did differ. Both cocaine and heroin abuse promoted neuroinflammation, increasing expression of ICAM-1 and recruiting CD3+ lymphocytes. Heroin affected the molecular integrity of tight junctions, as reflected by reduced ZO-1 expression. The outcomes of the present study are, overall, consistent with prior available evidence, which is almost exclusively from studies conducted in vitro or in animal models. These findings provide important information about the downstream consequences of neuroinflammation in drug abusers and may help to inform the development of potential therapeutic targets.
The Berkeley sample of Type II supernovae: BVRI light curves and spectroscopy of 55 SNe II
Authors: de Jaeger T , Zheng W , Stahl B E , Filippenko A V , Brink T G , Bigley A , Blanchard K , Blanchard P K , Bradley J , Cargill S K , Casper C , Cenko S B , Channa S , Choi B Y , Clubb K I , Cobb B E , Cohen D , de Kouchkovsky M , Ellison M , Falcon E , Fox O D , Fuller K , Ganeshalingam M , Gould C , Graham M L , Halevi G , Hayakawa K T , Hestenes J , Hyland M P , Jeffers B , Joubert N , Kandrashoff M T , Kelly P L , Kim H , Kim M , Kumar S , Leonard E J , Li G Z , Lowe T B , Lu P , Mason M , McAllister K J , Mauerhan J C , Modjaz M , Molloy J , Perley D A , Pina K , Poznanski D , Ross T W , Shivvers I , Silverman J M , Soler C , Stegman S , Taylor S , Tang K , Wilkins A , Wang Xiaofeng , Wang Xianggao , Yuk H , Yunus S , Zhang K D 
Published: September 2019

ABSTRACT
In this work, BVRI light curves of 55 Type II supernovae (SNe II) from the Lick Observatory Supernova Search programme obtained with the Katzman Automatic Imaging Telescope and the 1 m Nickel telescope from 2006 to 2018 are presented. Additionally, more than 150 spectra gathered with the 3 m Shane telescope are published. We conduct an analyse of the peak absolute magnitudes, decline rates, and time durations of different phases of the light and colour curves. Typically, our light curves are sampled with a median cadence of 5.5 d for a total of 5093 photometric points. In average, V-band plateau declines with a rate of 1.29 mag (100 d)−1, which is consistent with previously published samples. For each band, the plateau slope correlates with the plateau length and the absolute peak magnitude: SNe II with steeper decline have shorter plateau duration and are brighter. A time-evolution analysis of spectral lines in term of velocities and pseudo-equivalent widths is also presented in this paper. Our spectroscopic sample ranges between 1 and 200 d post-explosion and has a median ejecta expansion velocity at 50 d post-explosion of 6500 km s−1 (H α line) and a standard dispersion of 2000 km s−1. Nebular spectra are in good agreement with theoretical models using a progenitor star having a mass &lt;16M⊙. All the data are available to the community and will help to understand SN II diversity better, and therefore to improve their utility as cosmological distance indicators.
Risk Management Failures
Authors: Bouvard Matthieu , Lee Samuel 
Published: September 2019

Abstract
We model risk management as information acquisition that delays trading decisions. In markets with preemptive competition, this can lead to a race to the bottom, where prioritizing trade execution over risk management is optimal for each firm, but collectively inefficient. As time competition intensifies, mean trading profit supplants risk concerns as the main driver of risk management quality, causing risk misallocation to rise with trading speed and volume. This pathology of risk management failure—the trio of time-consuming risk assessment, preemptive competition, and boom markets—has distinctive regulatory implications.
Authors have furnished an Internet Appendix, which is available on the Oxford University Press Web site next to the link to the final published paper online.
How to calculate the ASDAS based on C-reactive protein without individual questions from the BASDAI: the BASDAI-based ASDAS formula
Authors: Aranda-Valera I Concepcion , Garrido-Castro Juan L , Ladehesa-Pineda Lourdes , Vazquez-Mellado Janitzia , Zarco Pedro , Juanola Xavier , Gonzalez-Navas Cristina , Font-Ugalde Pilar , Castro-Villegas M Carmen 
Published: September 2019

Abstract

Objectives
To develop a new equation to calculate the Ankylosing Spondylitis Disease Activity Score based on CRP (ASDAS-CRP) using only the BASDAI total score and CRP.

Methods
Axial SpA (axSpA) patients from the Cordoba Spondyloarthritis Registry cohort were recruited as a derivation cohort, while a retrospective sample from the Spanish Rheumatology Society National Registry of Spondyloarthropathies and Ibero American Spondyloarhtritis Registry registers was used as a validation cohort. We built a new equation based only on the BASDAI and CRP, defining a new formula: the BASDAI-based ASDAS (BASDAS). Linear regression analysis was used to determine the coefficients of the equation in the derivation cohort and it was subsequently validated in the validation cohort.

Results
A total of 52 axSpA patients in the derivation cohort and 3359 patients in the validation cohort were included. In the derivation cohort, the mean BASDAS [2.24 (s.d. 0.90)] was very similar to the ASDAS-CRP [2.23 (s.d. 0.95)], with a very strong correlation (r = 0.96, P &lt; 0.001). In the validation cohort, the mean BASDAS was 3.31 (s.d. 1.37) and the ASDAS-CRP was 3.19 (s.d. 1.27), which also had a very strong correlation (r = 0.95, P &lt; 0.001). Intraclass correlation coefficients were excellent in both cohorts (0.963 and 0.947, respectively).

Conclusion
The BASDAS performs similarly to the ASDAS-CRP and can be calculated with only the BASDAI total score and CRP, allowing evaluation of disease activity in retrospective studies where the individual items of the BASDAI are not available.
IN VIVO BIODOSIMETRY OF PORCINE T-LYMPHOCYTE SUBSETS AND NK CELLS
Authors: Andrejsová Lenka , Šinkorová Zuzana , Šinkora Jiří , Tichý Aleš , Filipová Alžběta , Němcová Markéta , Šinkora Marek 
Published: September 2019

AbstractThe aim of the present study was to evaluate the biodosimetric potential of peripheral blood lymphocytes, particularly of T-cell subsets (null and T helper) and natural killer cells (NK), upon exposure to gamma irradiation (60Co) in vivo. For this purpose, the change in relative numbers of NK cells and T-lymphocyte subsets, as well as in the H2AX phosphorylation rate, were evaluated as potential early markers of the lymphocytic response to irradiation in vivo. These experiments were performed on a Large White Pig model. As a result, significant but not dose-dependent changes in the proportion of lymphocyte subpopulations (NK cells, null and T helper cells) were found after exposure to ionising radiation in vivo. On the other hand, circulating NK cells showed relatively higher radioresistance capacity when compared to the T-lymphocyte subsets; however, gamma-H2AX expression showed no significant difference between the evaluated lymphocyte subsets.
Automatic detection of microsleep episodes with feature-based machine learning
Authors: Skorucak Jelena , Hertig-Godeschalk Anneke , Schreier David R , Malafeev Alexander , Mathis Johannes , Achermann Peter 
Published: September 2019

AbstractStudy ObjectivesMicrosleep episodes (MSEs) are brief episodes of sleep, mostly defined to be shorter than 15 s. In the electroencephalogram (EEG), MSEs are mainly characterized by a slowing in frequency. The identification of early signs of sleepiness and sleep (e.g. MSEs) is of considerable clinical and practical relevance. Under laboratory conditions, the maintenance of wakefulness test (MWT) is often used for assessing vigilance.MethodsWe analyzed MWT recordings of 76 patients referred to the Sleep-Wake-Epilepsy-Center. MSEs were scored by experts defined by the occurrence of theta dominance on ≥1 occipital derivation lasting 1–15 s, whereas the eyes were at least 80% closed. We calculated spectrograms using an autoregressive model of order 16 of 1 s epochs moved in 200 ms steps in order to visualize oscillatory activity and derived seven features per derivation: power in delta, theta, alpha and beta bands, ratio theta/(alpha + beta), quantified eye movements, and median frequency. Three algorithms were used for MSE classification: support vector machine (SVM), random forest (RF), and an artificial neural network (long short-term memory [LSTM] network). Data of 53 patients were used for the training of the classifiers, and 23 for testing.ResultsMSEs were identified with a high performance (sensitivity, specificity, precision, accuracy, and Cohen’s kappa coefficient). Training revealed that delta power and the ratio theta/(alpha + beta) were most relevant features for the RF classifier and eye movements for the LSTM network.ConclusionsThe automatic detection of MSEs was successful for our EEG-based definition of MSEs, with good performance of all algorithms applied.
Recommendations for Systemic Antimicrobial Therapy in Fracture-Related Infection: A Consensus From an International Expert Group
Authors: Depypere Melissa , Kuehl Richard , Metsemakers Willem-Jan , Senneville Eric , McNally Martin A. , Obremskey William T. , Zimmerli Werner , Atkins Bridget L. , Trampuz Andrej ,   on behalf of the Fracture-Related Infection (FRI) Consensus Group
Published: September 2019

Summary:
Fracture-related infection (FRI) is a major complication in musculoskeletal trauma and one of the leading causes of morbidity. Standardization of general treatment strategies for FRI has been poor. One of the reasons is the heterogeneity in this patient population, including various anatomical locations, multiple fracture patterns, different degrees of soft-tissue injury, and different patient conditions. This variability makes treatment complex and hard to standardize. As these infections are biofilm-related, surgery remains the cornerstone of treatment, and this entails multiple key aspects (eg, fracture fixation, tissue sampling, debridement, and soft-tissue management). Another important aspect, which is sometimes less familiar to the orthopaedic trauma surgeon, is systemic antimicrobial therapy. The aim of this article is to summarize the available evidence and provide recommendations for systemic antimicrobial therapy with respect to FRI, based on the most recent literature combined with expert opinion.

Level of Evidence:
Therapeutic Level V. See Instructions for Authors for a complete description of levels of evidence.
Analysis of Periorbital Soft Tissue in Thyroid Eye Disease
Authors: Mimura Masashi , Yang Patrick T. , Ko Audrey C. , Korn Bobby S. , Kikkawa Don O. 
Published: September 2019

Superior and inferior periorbital fat is enlarged in thyroid eye disease with the superior periorbital fat expansion correlating with orbital fat expansion.

Purpose:
To investigate periorbital tissue enlargement in thyroid eye disease (TED) by 3-dimensional CT volumetric analysis.

Methods:
Twenty-four adult subjects, 16 with TED and 8 controls, were studied. Three-dimensional volumetric calculations were performed on CT imaging of the orbit and face, focusing on the retroorbicularis oculi fat, suborbicularis oculi fat, facial muscles in periorbital region, orbital fat, extraocular muscles, and orbital volume. Analysis was performed using JMP version 12 software. Each measure was compared between the TED and control groups using Wilcoxon rank sum test. Correlations were investigated between periorbital and orbital tissue using the Spearman’s correlation coefficient method.

Results:
A statistically significant increase in volume was measured in TED patients in the superior and inferior periorbital fat tissue (p = 0.0044, p = 0.047), including the retroorbicularis oculi fat (p = 0.0011), suborbicularis oculi fat (p = 0.0093), and a decrease in facial muscle of superior periorbital region (p = 0.035). Strong positive correlation was noted between the muscles of superior and inferior periorbital region (r

s
= 0.65; p = 0.0006), and between the suborbicularis oculi fat and retroorbicularis oculi fat (r

s
= 0.50; p = 0.013). No correlation was observed between orbital and periorbital tissue, except between the orbital fat and the inferior periorbital fat tissue (p = 0.047).

Conclusions:
Facial fat in the periorbital region is enlarged in TED, with the superior component correlating with orbital fat tissue expansion. These findings may assist in the clinical evaluation and management of disfigurement in TED patients.