bluuebunny/crossref_metadata_2025_split huggingface dataset:
Saliva and Serum Lithium Monitoring in Hospitalized Patients and Possibility to Replace Serum to Saliva
Authors: Serdarević Nafija , Kozjek Franc , Malešič Ivan 
Published: May 2018

The lithium ions concentration in human serum and saliva was determined using dry-slide technology Vitros 250 Analyser (Ortho Clinical Diagnostic) and atomic absorption spectrometry Perkin Elmer 403 (AAS). We analyzed lithium ions in 100 serum and saliva specimens of patients after oral administration of lithium carbonate (3 x 300 mg) Jadran, Galen Laboratory Rijeka. Saliva and blood were taken 2 and 12 hours after the last dose. At the same time lithium ions at samples of blood and saliva were determined with both methods which showed high level of correlation. The mean difference of lithium ions between saliva and serum was statistically significant for p<0.05 using t student test. At saliva we got constant of elimination Kel = 0.02(-1)h and elimination half life (t(1/2)) was t(1/2)=34.6 h. For serum was t(1/2)= 24 h what means that lithium ions elimination is slower from saliva then from serum. That is the reason why probably concentration at saliva is higher then at serum. Lithium elimination is two compartment pharmacokinetic model where important part of compartment are saliva and salivary glands. At a certain point in medical treatment it could be expected to use controlled determination of lithium ions in saliva with serum as control.
Five-Year Survival After First-Ever Stroke
Authors: Smajlović Dževdet , Kojić Biljana , Sinanović Osman 
Published: May 2018

The aim of the study was to analyze the 5-year survival after first-ever ischemic stroke and intracerebral hemorrhage. In this study 836 patients were analyzed with a first-ever stroke admitted at the Department of Neurology Tuzla, Bosnia and Herzegovina, from January 1(st) 1997 to December 31(st) 1998. Of these 613 (73,3%) were ischemic strokes and 223 intracerebral hemorrhages (26,7%) Subarachnoid hemorrhages were excluded. After hospitalization surviving patients examined periodically, and a final examination was performed 5 years after the stroke. Overall, case-fatility at the first month was 36% (301/836) and the mortality rate was significantly higher in the patients with intracerebral hemorrhage (58,3% vs. 27,9%, p<0,0001). The first year survived 60% patients with ischemic stroke, and 38% with intracerebral hemorrhage. After 5 years, 188 (31%) patients with ischemic stroke and 53 (24%) with intracerebral hemorrhage were alive (p=0,5), and the cumulative survival rate for the entire study was 29%. Among 30-day survivors (n=535) surviving rate after 5 years was significantly higher in patients with intracerebral hemorrhage (57% vs. 42,5%, p=0,01). The survival rate was the highest for those 50 years and younger (57%), and the lowest for those aged over 70 years (9%). Predictors of 5-year mortality were older age and hypertension for both types of stroke, heart diseases for ischemic stroke and diabetes for intracerebral hemorrhage. Long-term survival after first-ever ischemic stroke and intracerebral hemorrhage is similar. However, among 30-day survivors the 5-year survival is better in patients with intracerebral hemorrhage.
Helicobacter Pylori as a Promoter of Accelerated Regeneration, Pathological Differentiation and Transformation of Normal Gastric Mucosa into Cancerous Type
Authors: Vukobrat-Bijedić Zora , Radović Svjetlana , Husić-Selimović Azra , Gornjaković Srđan 
Published: May 2018

The aim of the study was to ascertain presence of Helicobacter pylori in gastric carcinoma as a responsible promoter of inflammatory-regenerative changes, which lead to pathological differentiation and transformation of normal epithelial cells into intestinal type and, in progression, cause epithelial dysplasia that develops into early gastric carcinoma. The paper presents prospective study that includes clinical, pathohistological and microbiological aspects of carcinogenesis initiation in gastric mucosa. The subjects are patients treated at Gastroenterohepatology Clinic divided into two groups. One group included 50 patients with gastric carcinoma while the control group included 50 patients with chronic atrophic H. pylori positive gastritis. All the patients were subjected to endoscopy as well as biopsy targeted at antrum, lesser curvature and corpus and at the region 1-2 cm removed from tumor lesion. We used HUT test to verify H. pylori presence in biopsy samples. We analyzed the samples for presence, frequency and severity of inflammatory-regenerative, metaplastic and dysplastic changes in gastric mucosa and evaluated their meaning for the prognosis. Our study confirmed Helicobaster pylori responsibility for inflammatory events in gastric mucosa in patients with gastric carcinoma. Slight and mild epithelial dysplasia with chronic atrophic gastritis grade I and II coupled with intestinal metaplasia may be considered an indicator for early detection of carcinoma. Such patients represent risk group for gastric carcinoma development.
Two-criteria Dental Aging Method Applied to a Bosnian Population: Comparison of Formulae for Each Tooth Group Versus One Formula for all Teeth
Authors: Sarajlić Nermin , Cihlarž Zdenko , Klonowski Eva-Elvira , Selak Ivan , Brkić Hrvoje , Topić Berislav 
Published: May 2018

The purpose of this study was to obtain age estimation formulae using the length of periodontosis, transparency of the root and root height in each tooth group for the current male population in Bosnia and Herzegovina and to compare these formulae with Lamendin's and Prince's formulae. The research was undertaken on 847 single rooted teeth from 200 identified deceased persons, individuals who died between the ages of 23 and 85 years. Periodontosis, transparency and root height were measured according to Lamendin's procedure. All teeth were grouped in two ways: according to the tooth groups and to the age groups. The highest coefficients of correlation are obtained for maxillary canines (R = 0,731) and mandibular canines (R = 0,706) and the maxillary lateral incisors showed the lowest mean error (ME = 6,63 years). In age groups, the lowest mean error was obtained in the 40-49 years age group (ME = 5,15 years). Equations developed in this study give statistically significantly better age estimations in comparison to the original Lamendin and Prince formulae for the whole sample as well as for each tooth group, except for mandibular central incisors. Age estimation with models developed for each tooth group (except for mandibular lateral incisors) was statistically significantly better than models based on the whole sample.
Treatment aspects of primary nephrotic syndrome in adults
Authors: Rašić Senija , Unčanin Snježana , Džemidžić Jasminka , Aganović Kenana , Srna Amira , Rašić Ismar 
Published: May 2018

Strict therapy protocol, which would be used universally for certain morphological forms of primary nephrotic syndrome, does not exist. The aim of the study was to show the effects of used therapy protocol in treatment of primary nephrotic syndrome at the Institute of Nephrology, Clinical Center University of Sarajevo in period of 2000-2005. The retrospective analysis covered 48 patients (17 women and 31 men) with idiopathic nephrotic syndrome, where pathomorphological changes were proved by kidney biopsy. Minimal change disease was confirmed with 6 (12.5%) patients. All patients were initially treated with corticosteroids with dose of 1 mg/kg of body weight. Five patients were in the group of primary responders (83.3%) with long term total remission, and 1 patient (16.6%) was a primary responder with 3 relapses in 8 months with a therapy of corticosteroids and bolus of cyclophosphamide. Diffuse mesangial proliferative glomerulonephritis was shown in 13 patients (27.1%). Seven patients from this group were treated with corticosteroid therapy (1 mg/kg of body weight for 4 weeks, followed by 0.5 mg/ kg of body weight until therapeutical response was achieved, and finally gradual exclusion of therapy after eight weeks in responsive patients). Six patients were treated with corticosteroids and one-month of bolus cyclophosphamide during half of year (10-5 mg/kg of body weight). Total remission was achieved in 37,9% of the patients. The IgA nephropathy presented with the nephrotic syndrome was shown in 10.4% (5) of the patients. Three patients from this group were treated with corticosteroid therapy (1 mg/kg of body weight for 4 weeks, followed by 0,5 mg/ kg of body weight until therapeutical response was achieved, and finally gradual exclusion of therapy after eight weeks in responsive patients) and.2 patients with corticosteroids and cyclophosphamide (1.5 mg/kg of body weight) during 6 months. Complete remission of nephrotic syndrome from this pathomorphological category was achieved in 2 patients. Membranoproliferative glomerulonephritis was shown in 6 patients (12.5%). All were treated with corticosteroids plus bolus of cyclophosphamide. Partial remission was achieved in one patient. Membranous glomerulonephritis was confirmed in 18 patients (37.5 %). Combined therapy of corticosteroids and bolus of cyclophosphamide was used in 7/18 patients, in 2/18 patients therapy of corticosteroids and per os cyclophosphamide (2 mg/kg of body weight) and in 9/18 patients cyclosporine therapy (3 mg/kg of body weight). Complete remission was achieved in 38.8% of the patients. A high percentage of achieved remissions of primary nephrotic syndrome in adults shows the efficiency of immunomodulating therapy used. Membranoproliferative glomerulonephritis still remains a therapy problem.
Osteoporosis - Current Trends in Diagnosis and Management
Authors: Kulenović Indira , Rašić Senija , Kulenović Elvedin 
Published: May 2018

Osteoporosis (OP) is a generalized skeletal disorder characterized by low bone mineral density (BMD), deterioration of the microarchitecture of bone tissue and susceptibility to fracture. Most frequently it occurs in postmenopausal women and the aged. It is a chronic condition of multifactorial etiology and is a major global healthcare problem in developed and rising in developing countries. Patients with uncomplicated OP are usually asymptomatic which contributes to serious under-diagnosing of this potentially devastating condition. It is estimated that less than half of patients with OP are diagnosed in many developed countries. Therefore preventive measures and timely diagnosis have to be a key aspect of management of this disorder. In this article we briefly underline pato-physiology of the disorder, review current methods of measuring bone mineral density, describe risk factors and evaluate current and potential therapies.
56-os amerikai magyarok óhazaképe és a helyvesztés lépései
Authors: Bögre Zsuzsanna 
Published: May 2018

A tanulmány a georgiai magyar „church” 56-os tagjainak élettörténeti elemzését mutatja be. Az élettörténetekből megismerhetővé vált, hogy milyen óhazaképet őriznek azok a személyek, akik egykor úgy érezték, el kell hagyniuk hazájukat. Keveset tudunk még arról, s ezt a hiánypótlást célozta meg a kutatás, hogy hogyan gondolkodnak az óhazáról egy magyar diaszpóra tagjaként az amerikai magyarok, s hogyan küzdöttek meg az óhazától való elszakadással. A kutatás módszereként az oral history élettörténetek feldolgozását alkalmaztam. Az élettörténetekből négy meghatározó időpontot választottam ki, amelyekben az óhazával kapcsolatos történeteket elemeztem. Az óhazáról való beszédmód túlmutatott a szülőföldhöz való ragaszkodáson vagy annak elutasításán. Az óhazáról szóló vélemények történetekbe ágyazva fejezik ki az elszakadás lépéseit, amelyek szükségesek az új helykötődések kialakulásához. Láthatóan azok az amerikai magyarok, akik nem tervezik hazaköltözésüket, távolságtartó módon vélekednek szülőföldjükről. Az óhaza demisztifikálása az új hazához való kötődések kialakulásában nélkülözhetetlennek bizonyult.
Az óhazával kapcsolatos helyvesztés feldolgozásában nyújt segítséget a diaszpóra mint közösség. A sorstársakkal a diskurzusok során megosztott tapasztalatokból kialakult egyfajta kollektív vélekedés és emlékezés, és a kollektív szintre emelkedett emlékek megjelentek az egyének publikus élettörténeteiben.
Editorial
Authors: Lara José Edson 
Published: May 2018

EDITORIAL Estimado lector,Es con mucha satisfacción y honor que le ofrecemos este volumen 17, n ° 2 de la Revista Gestión & Tecnología. Por este periódico le ofrecemos artículos y relatos técnicos procedentes de las más diversas áreas en el vasto campo de la gestión y de la tecnología, y, especialmente, de la conjugación entre estos dos importantes segmentos del conocimiento científico y de acciones ejecutivas. Además, son contribuciones a la literatura procedentes de diversos autores vinculados a variadas instituciones de enseñanza e investigación en Brasil. Como siempre, estamos haciendo esfuerzos para la captación de artículos procedentes de otros países, como forma de proporcionar la integración de ideas, programas de investigación y publicaciones, así como de culturas científicas específicas.
Editorial
Authors: Lara José Edson 
Published: May 2018

Prezado Leitor, Conforme Platão (Fedón), “parece-me, pois, que se há algo belo à margem do belo em si, não será belo por nenhum outro motivo, salvo porque participa daquela beleza”. Assim, a beleza da produção científica se complementa na integridade e na integralidade da publicação científica. A identidade da produção se reflete na imagem da publicação. Entretanto, a própria publicação é dotada de identidade própria e esta reflete em sua imagem, no contexto da densidade epistemológica, teórica, morfológica, tecnológica e métrica das abordagens, manifestada na estética específica de um texto científico. Assim, o texto deve ser dotado de densidade científica e técnica, mas expressar uma estética que releve a beleza do mundo da ciência.
Meningkatkan Pemahaman Konsep Siswa Kelas XI IPA 3 MAN 3 Banjarmasin Melalui Pengajaran Langsung Berbantuan Media Virtual
Authors: Hadijah Siti , Jamal Muhammad Arifuddin , M. Abdul Salam 
Published: May 2018

Pemahaman konsep siswa yang rendah berakibat pada hasil belajar yang diperoleh juga rendah. Oleh karena itu dilakukan suatu penelitian untuk meningkatkan pemahaman konsep siswa melalui pengajaran langsung berbantuan media virtual dengan tujuan khusus sebagai berikut: (1) mendeskripsikan keterlaksanaan RPP, (2) medeskripsikan aktivitas siswa selama pembelajaran, dan (3) mendeskripsikan pemahaman konsep siswa yang ditinjau dari tes hasil belajar siswa mencakup kategori menginterpretasi, memberi contoh, membandingkan, dan menjelaskan. Penelitian ini merupakan penelitian PTK model Hopkins. Subyek penelitian adalah siswa kelas XI IPA 3 MAN 3 Banjarmasin. Data diperoleh melalui lembar observasi keterlaksanaan RPP, lembar observasi aktivitas siswa, dan hasil tes belajar pemahaman konsep siswa. Teknik analisis data yang digunakan bersifat deskriptif. Hasil penelitian menunjukkan, (1) keterlaksanaan RPP berkategori sangat baik, (2) aktivitas siswa berkategori baik, (3) pemahaman konsep siswa pada siklus I berkategori tidak tuntas karena tidak mencapai ketuntasan klasikal yaitu sebesar 61.29% dan pada siklus II berkategori tuntas karena mencapai ketuntasan klasikal yaitu sebesar 80.64%.
Pengembangan Perangkat Pembelajaran Berorientasi Lingkungan Sekitar Bantaran Sungai Barito Untuk Melatihkan Keterampilan Proses Sains
Authors: Ihsan Imam Nor , Jamal Muhammad Arifuddin , M. Abdul Salam 
Published: May 2018

Pada proses perangkat pembelajaran di sekolah dinilai masih kurang layak. Hal ini berimplikasi pada keterampilan proses sains dan hasil belajar kognitif siswa yang rendah. Untuk itu dilakukan pengembangan perangkat pembelajaran menggunakan model inkuiri terbimbing yang memiliki tujuan khusus: (1) mendeskripsikan validitas perangkat pembelajaran, (2) mendeskripsikan kepraktisan perangkat pembelajaran yang ditinjau dari keterlaksanaan RPP, (3) Mendeskripsikan efektivitas perangkat pembelajaran yang ditinjau dari hasil belajar kognitif siswa, dan (4) mendeskripsikan pencapaian keterampilan proses sains siswa. Pada penelitian ini model yang digunakan model Dick and Carey. Instrumen yang dikembangkan berupa RPP, LKS, THB dan Materi ajar. Teknik pengumpulan data berupa validasi perangkat pembelajaran, pengamatan keterlaksanaan RPP, pengamatan KPS siswa, dan tes hasil belajar. Teknik analisis data berupa deskriptif kualitatif dan kuantitatif. Hasil penelitian menunjukkan: (1) validitas perangkat pembelajaran berkategori valid, (2) kepraktisan perangkat pembelajaran dinilai terlaksana sangat baik, (3) efektifitas perangkat pembelajaran dinilai efektif, dan (4) pencapaian keterampilan proses sains siswa dinilai sangat baik. Diperoleh simpulan bahwa perangkat pembelajaran menggunakan model inkuiri terbimbing yang dikembangkan layak digunakan dalam pembelajaran. Learning device used in the learning process in schools is still considered less worthy. This has implications for science process skills and cognitive learning outcomes of students is low. To that made the development of the learning device by using the model of guided inquiry which has specific objectives: (1) describe the validity of the study, (2) describe the practicality of the device learning in terms of enforceability of RPP, (3) Describe the effectiveness of the learning in terms of the cognitive learning students, and (4) describe the achievement of science process skills of students. This research is a development which refers to the development model of Dick and Carey. The instrument was developed in the form of lesson plans, worksheets, THB and teaching materials. Technique data collecting device validation study, observation keterlaksanaan RPP, observations KPS students, and the achievement test. Data analysis techniques in the form of qualitative and quantitative descriptive. The results showed: (1) the validity of the learning device category is valid, (2) the practicality of the learning device rated executed very well, (3) the effectiveness of the learning device is considered effective, and (4) the achievement of science process skills of students rated as excellent. Be concluded that the device is guided inquiry learning model developed eligible for use in learning.
Pengembangan Media Pembelajaran Menggunakan Slide Presentasi 3 Dimensi Sebagai Multimedia Interaktif Pada Pokok Bahasan Kalor Untuk Siswa SMP
Authors: Widodo Oki , An'nur Syubhan , Mahardika Andi Ichsan 
Published: May 2018

Penggunaan media pendidikan dapat membantu guru dalam menyampaikan materi pembelajaran. Kebanyakan kegiatan belajar disekolah termasuk di SMP Negeri 13 Banjarmasin, berdasarkan pengamatan yang dilakukan peneliti terlihat bahwa dalam memotivasi siswa dengan membawa benda atau objek yang nyata sulit dilakukan dalam setiap pembelajaran. Hal ini menyebabkan peneliti mengembangkan media ajar slide presentasi 3 dimensi untuk mengatasi permasalahan tersebut. Tujuan penelitian ini: (1) mendeskripsikan validitas media ajar menggunakan slide presentasi 3 dimensi, (2) mendeskripsikan kepraktisan media ajar menggunakan slide presentasi 3 dimensi, (3) mendeskripsikan efektivitas media ajar menggunakan slide presentasi 3 dimensi. Penelitian ini merupakan penelitian pengembangan yang mengacu pada model pengembangan ADDIE. Subjek ujicoba adalah siswa kelas VII H di SMP Negeri 13 Banjarmasin. Data diperoleh melalui lembar validasi media, lembar keterlaksanaan , dan tes hasil belajar. Teknik analisis data menggunakan validitas, reliabilitas, dan uji gain. Hasil penelitian menunjukkan, (1) media ajar yang dinyatakan valid dengan kategori baik, (2) kepraktisan media ajar adalah terlaksana sangat baik, dan (3) efektifitas media ajar dinyatakan efektif. Simpulan penelitian adalah bahwa media ajar menggunakan slide presentasi 3 dimensi layak untuk digunakan. Utilization of media education can help teachers to deliver lessons. Most of school learning activities included in SMP Negeri 13 Banjarmasin, based on observations conducted research revealing that in motivating students to bring a tangible object or objects hard to do in each lesson. It cause researchers to develop instructional media 3 dimensional presentation slides to overcome these problems. The purpose of this study: (1) describe the validity of instructional media using 3-dimensional presentation slides, (2) describe the practicality of teaching media using 3-dimensional presentation slides, (3) describe the effectiveness of instructional media using 3-dimensional presentation slides. This research is a development which refers to the ADDIE development model. Test subject is class of VII H SMP Negeri 13 Banjarmasin. Data obtained through the validation sheet media, sheet of feasibility, and achievement test. Data were analyzed using the validity, reliability, and gain test. The results showed, (1) instructional media to state valid by either category, (2) practicality media feasibility teaching is very good, and (3) the effectiveness of instructional media of state effective. The inference is that media teaching research using 3 dimensional presentation slides unfit for use.
Meningkatkan Hasil Belajar Siswa Kelas VIII A SMP Negeri 26 Banjarmasin Dengan Menggunakan Model Quantum Teaching Pada Materi Ajar Tekanan
Authors: Rahmawati Nor , Mastuang Mastuang , Misbah Misbah 
Published: May 2018

Low of student learning result in science researcher doing lesson because the students are rarely directly involved in learning. Therefore, research that aims to improve learning result. This research aimed to describe (1) teaching materialize, (2) students’ learning result in cognitive aspect and (3) student activity. The method used is a Kemmis & Mc Taggart classroom action research model, with each cycle countain of planning, implementation, observation, and reflection steps. The subjects of this research were 36 students of VIIIth A grade. Technique of data collecting is learning result test, observation sheets, and documentation. Results of this research shown that by applying quantum teaching model (1) teaching materialize on 1st cycle categorized good, on 2nd and 3rd cycles is excellent, (2) completeness of students learning result improve concucivelly individual completeness percentage on 1st, 2nd and 3rd cycles are 69,44%, 77,78% and 94.44%, (3) student activities improve in every aspect with good categorize, except aspects asking questions aspect to teaching, not relevan behavior and express opinion on 1st cycle is categorized good enough, but on 2nd and 3rd cycle improve with consecutivelly categorized good and excellent. The conclusion that to in order to improve students learning result of VIIIth A grade SMP Negeri 26 Banjarmasin can improved by using quantum teaching model on pressure subject.