bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is delayed graft function associated with ureteral stenosis in the kidney transplant recipient? A case-control study
Authors: Cayetano-Alcaraz Axel , Rodriguez-Alvarez Juan Sebastian , Vilatobá-Chapa Mario , Alberú-Gómez Josefina , Gabilondo-Pliego Bernardo , Rodríguez-Covarrubias Francisco , Morales-Buenrostro Luis Eduardo , Méndez-Probst Carlos Enrique 
Published: February 2019

Introduction: Ureteral stricture (US) in the kidney transplant recipient is a rare complication that can lead to morbidity and graft loss. Risk factor recognition is crucial in the prevention and management of this entity. Delayed graft function (DGF), as defined by the need for dialysis in the first week after transplantation, has been proposed as a risk factor in previous studies. Our objective is to determine the impact of DGF in US development in kidney transplant patients.
Methods: We designed a matched case-control study. US cases in kidney transplant recipients were identified in the 2008–2017 period. We defined US as the rise in serum creatinine associated with findings suggesting obstruction in ultrasound, scintigraphy, or retrograde pyelogram; any other cause of graft dysfunction was excluded. Controls were defined as kidney transplant recipients from the same population and period without US, matched in a 1:2 fashion by age, sex, and donor type.
Results: From 532 kidney transplant patients, 31 cases and 62 controls were included. Cumulative US incidence was 58 per 1000 cases. When calculating for odds ratio (OR), post-operative urinoma (OR 3.2; 95% confidence interval [CI] 2.36–4.37) and ureteral duplication (OR 3.29; 95% CI 2.40–4.51) were associated with an increased risk for US, while DGF was not found to be statistically significant as a risk factor (OR 3.3; 95% CI 0.96–11.52). No statistically significant differences were found between groups in other pre- and post-transplant-related factors.
Conclusions: DGF was not associated with US in our cohort; however, ureteral duplication and postoperative urinoma were associated with an increased risk of graft ureteral stenosis development.
De uitdagingen in het effectief aanpakken van stalking
Authors: Voerman Bianca , Brandt Cleo 
Published: February 2019

A new approach to policing stalking in the Netherlands
In 2016 an independent review into a deadly ex-partner stalking caseEenhoorn Commission. (2016). Conclusies en aanbevelingen: Onderzoeksrapport TweeSteden. identified a number of structural problems in the police’s approach to stalking cases. Police struggle to accurately and effectively assess and respond to stalking cases because of several reasons. Police often fail to identify stalking by focusing too much on single incidents, missing the pattern of behaviours that constitute stalking. Investigations also focus on the criminal offence of stalking, with police waiting to take action until a particular threshold is reached. There is a lack of knowledge about stalking in general and risk factors associated with stalking in particular, which means the victim’s safety can be at stake if adequate security measures are not taken. These findings led to the development of a new structured response to ex-partner stalking cases, which consists of an automated query, case screening and prioritisation with the SASHMcEwan, T. E., Strand, S., MacKenzie, R. D., & James, D. V. (2015). Screening Assessment for Stalking and Harassment (SASH)., case management together with partner agencies and improved training for police officers who are handling stalking cases. Victim safety must always be the first priority.
Het leefklimaat in Nederlandse penitentiaire inrichtingen: de Life In Custody–studie
Authors: Palmen Hanneke , Bosma Anouk , van Ginneken Esther 
Published: February 2019

The Quality of Prison Life in Dutch prisons: the Life In Custody study
The Life In Custody-study is a large scale, prospective panel study, aimed to examine the quality of prison life in The Netherlands. This paper describes the LIC-study by giving a detailed overview of the data collection procedure, and strategies to optimize response, and presents the first nationwide results on prison climate in The Netherlands. Results show that the data collection procedures utilized were successful in obtaining a high response rate (which was an exceptional 81%) and reaching a representative group of prisoners. Furthermore, results show that the perceptions of prison climate vary across prison regimes, and to a lesser extent across age groups and time spent in detention.
Continuing Professional Development for Lecturers at the National University of Lesotho: Milestones and Challenges
Authors: Tlali Tebello 
Published: February 2019

This article appraises efforts by the National University of Lesotho (NUL) to provide continuing professional development for lecturers. The findings of a previous study suggested that the majority of lecturers at this university were not trained as teachers and that this could negatively impact on their teaching. The establishment of a staff academic development center was long overdue. In April 2014, the university established the Centre for Teaching and Learning (CTL). Drawing on a constructivist perspective, a qualitative approach was adopted to explore the current situation. The findings indicate that efforts to roll out continuing professional development for lecturers have not borne any significant results. The problem is exacerbated by a lack of support from the university community as well as lecturers’ poor attendance at the staff academic development workshops hosted by the CTL. It is thus recommended that management put mechanisms in place to support the center and ensure compulsory staff participation. Cet article vise à évaluer les moyens mis en place par l’Université Nationale du Lesotho (National University of Lesotho ou NUL) pour offrir une formation professionnelle continue aux Maîtres de conférence. Une précédente recherche a démontré que la majorité des Maîtres de conférence de cette université ne recevait pas de formation en tant qu’enseignants, ce qui pouvait avoir un impact négatif sur leur activité d’enseignement. Il était donc grand temps de créer un centre de formation pour le personnel universitaire. En avril 2014, l’université a inauguré un Centre d’Enseignement et d’Apprentissage (Centre for Teaching and Learning ou CTL). A partir d’un point de vue constructiviste, la situation actuelle a été examinée selon une approche qualitative. Les résultats de cette recherche indiquent que les moyens mis en place pour proposer aux Maîtres de conférence une formation professionnelle continue n’ont pas été concluants. Le problème est accentué par un manque de soutien de la part de la communauté universitaire et par les absences répétées des Maîtres de conférence aux ateliers de formation organisés par le CTL pour le personnel universitaire. Il serait pertinent que la direction mette en place des mécanismes permettant de soutenir le Centre et de rendre la participation du personnel obligatoire.
Kolofon
Authors: Høyrup Helene 
Published: February 2019

Kolofon1. årgang, nr. 1/2, udgivet marts 2012ISSN 2245-2931 ISSN (online) 2245-294X © Forfatterne og Det Informationsvidenskabelige Akademi. Det er tilladt at kopiere frit til privat brug med tydelig kildeangivelse. Kopiering i større omfang til undervisningsbrug o.l. kan kun ske efter indhentning af forfatternes og IVA’s tilladelse eller i henhold til kopieringsaftale med Copy-Dan.Redaktion: Helene Høyrup (ansvh.)Jette HyldegårdTrine SchreiberRedaktør af dette nummer:Helene HøyrupLayout: Bruno KjærIllustrationer til dette nummer:Felix Pedersen
Kolofon
Authors: Andersen Jack 
Published: February 2019

Kolofon
3. årgang, nr. 1, udgivet juli 2014

ISSN 2245-2931
ISSN (online) 2245-294X
© Forfatterne og Det Informationsvidenskabelige Akademi. Det er tilladt at kopiere frit til privat brug med tydelig kildeangivelse. Kopiering i større omfang til undervisningsbrug o.l. kan kun ske efter indhentning af forfatternes og IVA’s tilladelse eller i henhold til kopieringsaftale med Copy-Dan.
Redaktion:
Jack Andersen (ansvh.)
Nanna Kann-Rasmussen
Trine Schreiber

Redaktører af dette nummer:
Jack Andersen
Nanna Kann-Rasmussen
Trine Schreiber
Layout: Bruno Kjær

Illustrationer til dette nummer:
Erik Øckenholt
Kolofon
Authors: Kann-Rasmussen Nanna 
Published: February 2019

Kolofon5. årgang, nr. 1, udgivet februar 2016 ISSN 2245-2931 ISSN (online) 2245-294X © Forfatterne og Det Informationsvidenskabelige Akademi. Det er tilladt at kopiere frit til privat brug med tydelig kildeangivelse. Kopiering i større omfang til undervisningsbrug o.l. kan kun ske efter indhentning af forfatternes og IVA’s tilladelse eller i henhold til kopieringsaftale med Copy-Dan.Redaktion: Nanna Kann-Rasmussen (ansvh.) Trine Schreiber Redaktører af dette nummer: Maibritt Borgen Nanna Bonde Thylstrup Kristin VeelLayout: Bruno Kjær Illustrationer til dette nummer: Kristoffer Ørum
Kolofon
Authors: Kann-Rasmussen Nanna 
Published: February 2019

Kolofon5. årgang, nr. 3, udgivet november 2016 ISSN 2245-2931 ISSN (online) 2245-294X © Forfatterne og Det Informationsvidenskabelige Akademi. Det er tilladt at kopiere frit til privat brug med tydelig kildeangivelse. Kopiering i større omfang til undervisningsbrug o.l. kan kun ske efter indhentning af forfatternes og IVA’s tilladelse eller i henhold til kopieringsaftale med Copy-Dan.Redaktion: Nanna Kann-Rasmussen (ansvh.) Trine Schreiber Maria Skou Nicolaisen Lisa Engström Martin Persson Mimi Lindegaard Hansen (layout/administration) Redaktører af dette nummer: RedaktionenBilledredaktør: Bruno Kjær Illustrationer til dette nummer: Lars Brorson Fich Opdateret 24-01-2017
”Jeg prøvede så mange forskellige slankekure, nu vil jeg gøre det anderledes” – Et single-casestudie af coaching til vægttab
Authors: Stelter Reinhard 
Published: February 2019

I dette single-casestudie præsenterede forfatteren en dybdegående beskrivelse og analyse af en coaching intervention med fokus på vægttab, gennemført over 10 sessioner i løbet af 17 måneder. Klienten var en veluddannet kvinde i slutningen af 30’erne, som havde prøvet forskellige former for slankekure gennem årene med lille og ingen varig effekt. I sin coachende tilgang gik forfatteren ud over en ren adfærdsændrings model, hvilken tager udgangspunkt i Health Belief Modellen, og derimod forsøgte at tage et holistisk perspektiv, hvor klienten lærte at forbinde specifikke begivenheder og vaner i hendes arbejdsliv og fritid med specifikke spisevaner. I deres kollaborative praksis, iværksatte coachen og samtalepartneren ændringer både med hensyn til kost, fysisk aktivitet og sund livsstil, generelt. I et teoretisk afsnit bliver ændringerne i forståelsen med hensyn til overspisning præsenteret. Slutteligt, bliver en intra-aktiv model, hvori klienten betragtes som et selv-reflekterende individ, brugt som teoretisk udgangspunkt. En narrativ analyse af første session og en tværgående undersøgelse er udført for at vise, analysere og forstå proceduren for den coachende tilgang. Afslutningsvist er den coachedes stemme hørt med hensyn til hendes personlige oplevelser i løbet af processen. Datamaterialet var baseret på lydoptagelser af udvalgte sessioner, notater skrevet af coachen fra hver session, og afsluttende refleksioner fra den coachede.

Nøgleord: Sundhedscoaching, livstilsændring, meningsskabelse, casestudie, overvægt, fedme, kost, fysisk aktivitet, vægttab
EL GOBIERNO DE LAS AGUAS POR INSTITUCIONES COMUNITARIAS. LA DESMUNICIPALIZACIÓN EN LA ACEQUIA DE ESCALONA (1591-1783)
Authors: Peris Albentosa Tomás 
Published: February 2019

La historiografía viene proponiendo un doble modelo en lo que concierne a la imbricación de las instituciones políticas locales en el gobierno de las aguas y la gestión hidráulica realizada: acequias sometidas a control municipal, en las que correspondía a los ediles del consitorio adoptar decisiones relevantes y ejercer jurisdicción, frente a una minoría exigua de macrosistemas en los que los colectivos de regantes realizaron una gestión autónoma. En otros trabajos he cuestionado esta dicotomía en l’Horta, recalcando que la imbricación de instituciones municipales y oficiales de la monarquía fue allí relevante (Peris, 1992, 2003a, 2014a, 2014b). El presente artículo, que combina referencias sobre el contexto general valenciano con un estudio de caso, recalca que el gobierno de las aguas y su gestión cotidiana estuvieron sometidos a fuertes mutaciones, lo que impide mantener la tipología aludida, al menos con la rigidez con que suele plantearse. Para demostrarlo, analizo la acequia de Escalona. Hasta 1731 funcionó como un canal municipal muy completo. Sin embargo, problemas económicos del cabildo, dificultades para mantener operativas las infraestructuras hidráulicas, así como la creciente entidad de la propiedad forastera colapsaron dicha fórmula. Desde 1731, la acequia se desgajó del Ayuntamiento y pasó a manos de una Junta de Electos que representaba al conjunto de usuarios. Se trata de un ejemplo precoz de pérdida de competencias ejercidas por los municipios que segeneralizó durante la Revolución Liberal hasta dar paso al binomio Estado-comunidades de regantes que caracteriza a la época Contemporánea.
ALIANZAS ANTI-EMBALSE Y LUCHAS HIDRO-EPISTEMOLÓGICAS. LOS RETOS DE LA GESTIÓN COLECTIVA DEL AGUA EN EL RÍO GRANDE, MÁLAGA, ESPAÑA
Authors: Duarte Abadía Bibiana , Boelens Rutgerd , Du Pré Lucas 
Published: February 2019

En este artículo analizamos las luchas epistemológicas y retos que ha tenido el movimiento social en la subcuenca del río Grande frente a los diversos proyectos modernizadores que intentan transferir el agua rural hacia la ciudad de Málaga. El primero asociado a la construcción de un gran embalse y el segundo con la modernización de los sistemas de riego tradicionales. Concluimos que el reto está en desenmascarar el régimen de verdad que respalda los proyectos de modernidad hidráulica, reivindicar los derechos de uso y control colectivos del agua y así generar procesos de apropiación comunitaria para la defensa del río como un bien socio-ambiental, económico-cultural y político-epistemológico.
HACIA LA SOBERANIA ALIMENTARIA, ENTRE LA REORGANIZACION INSTITUCIONAL Y LA INICIATIVA LOCAL. EL PROYECTO COMUNITARIO DE RIEGO DE MARIANO ACOSTA (ECUADOR)
Authors: Recalt Christine , Valony Marie-Jeanne 
Published: February 2019

Ecuador es una de las primeras naciones que ha incorporado en su texto constitucional el concepto de soberanía alimentaria. En su Carta Magna de 2008, el artículo 281 señala que la soberanía alimentaria constituye un objetivo estratégico y una obligación, y el artículo 282 requiere que el Estado prohíba el acaparamiento o la privatización del agua. En este contexto, la gestión y la regulación de los recursos hídricos han generado divergencias entre las autoridades centrales y las comunidades rurales. La aprobación de la Ley de Aguas de 2014 ha avivado estas discrepancias. A través del análisis del proyecto comunitario de Mariano Acosta en la provincia de Imbabura, este artículo cuestiona si los proyectos y las normas de riego promovidas por las agencias gubernamentales pueden ser compatibles con las posibilidades de las comunidades campesinas para alcanzar la “soberanía alimentaria”. Losresultados muestran que cada uno de los actores implicados parece perseguir agendas distintas.
MINERÍA DE ORO: PROMESAS, CONFLICTOS Y DESILUSIÓN EN CERRO DE SAN PEDRO, MÉXICO
Authors: Stoltenborg Didi , Boelens Rutgerd 
Published: February 2019

Este artículo analiza los conflictos por los recursos agua y tierra en Cerro de San Pedro, México, cuando una empresa minera canadiense inició una mina a cielo abierto en este municipio. Examinamos diferentes posiciones en el conflicto entre la mina de oro y los habitantes locales, y cómo ambivalentes regulaciones nacionales y organismos gubernamentales permitieron que una empresa extranjera operara sin los permisos requeridos. Para analizar el conflicto utilizamos el marco de Escalones de Análisis de Derechos, que distingue cuatro capas de disputa: sobre los recursos; el contenido de las normas; el poder de decisión; y los discursos. Discutimos cómo la auto-representación de la empresa extranjera mediante discursos de responsabilidad social empresarial contrasta con las injusticias ambientales, políticas y sociales que infligen a los habitantes locales, exacerbadas por las políticas nacionales y los acuerdos comerciales internacionales. Por último, argumentamos que las alianzas multi-actoras y multi-escalapueden ofrecer oportunidades para fomentar soluciones ambientales y de justicia social.
Identification of a novel potassium channel (GiK) as a potential drug target in Giardia lamblia: Computational descriptions of binding sites
Authors: Palomo-Ligas Lissethe , Gutiérrez-Gutiérrez Filiberto , Ochoa-Maganda Verónica Yadira , Cortés-Zárate Rafael , Charles-Niño Claudia Lisette , Castillo-Romero Araceli 
Published: February 2019

Background
The protozoan Giardia lamblia is the causal agent of giardiasis, one of the main diarrheal infections worldwide. Drug resistance to common antigiardial agents and incidence of treatment failures have increased in recent years. Therefore, the search for new molecular targets for drugs against Giardia infection is essential. In protozoa, ionic channels have roles in their life cycle, growth, and stress response. Thus, they are promising targets for drug design. The strategy of ligand-protein docking has demonstrated a great potential in the discovery of new targets and structure-based drug design studies.

Methods
In this work, we identify and characterize a new potassium channel, GiK, in the genome of Giardia lamblia. Characterization was performed in silico. Because its crystallographic structure remains unresolved, homology modeling was used to construct the three-dimensional model for the pore domain of GiK. The docking virtual screening approach was employed to determine whether GiK is a good target for potassium channel blockers.

Results
The GiK sequence showed 24–50% identity and 50–90% positivity with 21 different types of potassium channels. The quality assessment and validation parameters indicated the reliability of the modeled structure of GiK. We identified 110 potassium channel blockers exhibiting high affinity toward GiK. A total of 39 of these drugs bind in three specific regions.

Discussion
The GiK pore signature sequence is related to the small conductance calcium-activated potassium channels (SKCa). The predicted binding of 110 potassium blockers to GiK makes this protein an attractive target for biological testing to evaluate its role in the life cycle of Giardia lamblia and potential candidate for the design of novel antigiardial drugs.
Trends in fragmentation and connectivity of Paspalum quadrifarium grasslands in the Buenos Aires province, Argentina
Authors: Gandini Marcelo L. , Lara Bruno D. , Moreno Laura B. , Cañibano Maria A. , Gandini Patricia A. 
Published: February 2019

Background
Despite its wide distribution worldwide, only 4.6% of temperate grasslands are included within systems of protected areas. In Argentina, this situation is even more alarming: only 1.05% is protected. The study area (central area of the southern Salado River basin) has a large extent of grasslands of Paspalum quadrifarium (Pq) which has been target since the middle of the last century of a variety of agricultural management practices including fire burning for cattle grazing.

Methods
Five binary images of presence-absence data of Pq from a 42-year range (1974–2016) derived from a land cover change study were used as base data. Morphological Spatial Pattern Analysis (MSPA), Morphological Change Detection (MCD) and Network Connectivity Analysis (NCA) were performed to the data using Guidos Toolbox (GTB) for the estimation of habitat and connectivity dynamics of the Pq patches (fragments).

Results
A loss of the coverage area and habitat nuclei of this grassland was observed during the study period, with some temporal oscillation but no recovery to initial states. Additional drastic reduction in connectivity was also evident in resulting maps. The number of large Pq grassland fragments (>50 ha) decreased at beginning of the study period. Also, fragmentation measured as number of components (patches) was higher at the end of the study period. The Pq pajonal nuclei had their minimum representativeness in 2000, and recovered slightly in area in 2011, but with a significant percentage increase of smaller patches (=islets) and linear elements as bridges and branches. Large corridors (mainly edge of roads) could be observed at the end of the study period, while the total connectivity of the landscape pattern drops continuously. Statistics of links shows mean values decreasing from 1974 to 2016. On the other hand, maximum values of links decreased up to 19% in 2011, and recovered to a 54% of their original value in 2016.

Discussion
Pq fragmentation and habitat reduction could have an impact on the ecosystem functioning and the mobility of some species of native fauna. The connecting elements of the landscape were maintained and/or recovered in percentage in 2011 and 2016. This fact, although favoring the dispersion of the present diversity in the habitat nuclei could cause degradation by an edge effect. Part of the area has the potential to be taken as an area of research and as an example of livestock management, since it is the one that would most preserve the biodiversity of the Pq environment. On the methodological side, the use of a proved tool as GTB is useful for monitoring dynamics of a grassland-habitat fragmentation.
A metabolomic approach to identifying biomarkers in blood of Alzheimer's disease
Authors: Lin Chia‐Ni , Huang Chin‐Chang , Huang Kuo‐Lun , Lin Kun‐Ju , Yen Tzu‐Chen , Kuo Hung‐Chou 
Published: February 2019

AbstractObjectiveThis study aims to identify metabolites with altered levels of expression in patients with early and progressive stages of Alzheimer's disease (AD).MethodsAll participants of the study underwent genetic screening and were diagnosed using both neuropsychological assessment and amyloid imaging before metabolome analysis. According to these assessments, the patients were classified as normal (n = 15), with mild cognitive impairment (n = 10), and with AD (n = 15).ResultsUsing a targeted metabolomic approach, we found that plasma levels of C3, C5, and C5‐DC acylcarnitines, arginine, phenylalanine, creatinine, symmetric dimethylarginine (SDMA) and phosphatidylcholine ae C38:2 were significantly altered in patients with early and progressive stages of AD. We created a predictive model based on the decision tree that included three main parameters: age, arginine and C5 plasma concentrations. The model distinguished AD patients from other participants with 60% sensitivity and 86.7% specificity. For healthy controls, the sensitivity was 85.7% and specificity was 61.5%. Multivariate ROC analysis to develop a decision tree showed that our model reached moderate diagnostic power in differentiating between older adults who are cognitively normal (AUC = 0.77) and those with AD (AUC = 0.72).InterpretationThe plasma levels of arginine and valeryl carnitine, together with subject age, are promising as biomarkers for the diagnosis of AD in older adults.