The ESC-EORP EURO-ENDO (European Infective Endocarditis) registry
Authors: Habib Gilbert , Lancellotti Patrizio , Erba Paola-Anna , Sadeghpour Anita , Meshaal Marwa , Sambola Antonia , Furnaz Shumaila , Citro Rodolfo , Ternacle Julien , Donal Erwan , Cosyns Bernard , Popescu Bogdan , Iung Bernard , Prendergast Bernard , Laroche Cécile , Tornos Pilar , Pazdernik Michal , Maggioni Aldo , Gale Chris P ,   EURO-ENDO Investigators, Ali Tatar-Chentir N N , Al-Mallah M , Astrom Aneq M , Athanassopoulos G , Badano L P , Benyoussef S , Calderon Aranda E , Cardim N M , Chan K-L , Cosyns B , Cruz I , Edvardsen T , Goliasch G , Habib G , Hagendorff A , Hristova K , Iung B , Kamp O , Kang D-H , Kong W , Matskeplishvili S , Meshaal M , Mirocevic M , Neskovic A N , Pazdernik M , Plonska-Gosciniak E , Popescu B A , Prendergast B , Raissouni M , Ronderos R , Sade L E , Sadeghpour A , Sambola A , Sengupta S , Separovic-Hanzevacki J , Takeuchi M , Tucay E , Tude Rodrigues A C , Varga A , Vaskelyte J , Yamagata K , Yiangou K , Zaky H , Granada I , Mahia M , Ressi S , Nacinovich F , Iribarren A , Fernandez Oses P , Avegliano G , Filipini E , Obregon R , Bangher M , Dho J , Cartasegna L , Plastino M L , Novas V , Shigel C , Reyes G , De Santos M , Gastaldello N , Granillo Fernandez M , Potito M , Streitenberger G , Velazco P , Casabé J H , Cortes C , Guevara E , Salmo F , Seijo M , Weidinger F , Heger M , Brooks R , Stöllberger C , Ho C-Y , Perschy L , Puskas L , Binder C , Rosenhek R , Schneider M , Winter M-P , Hoffer E , Melissopoulou M , Lecoq E , Legrand D , Jacquet S , Massoz M , Pierard L , Marchetta S , Dulgheru R , ´Emal C D , Oury C , Droogmans S , Kerkhove D , Plein D , Soens L , Weytjens C , Motoc A , Roosens B , Lemoine I , Rodrigus I , Paelinck B , Amsel B , Unger P , Konopnicki D , Beauloye C , Pasquet A , Vanoverschelde J L , Pierard S , Vancraeynest D , Sinnaeve F , Andrade J L , Staszko K , Dos Santos Monteiro R , Miglioranza M H , Shuha D L , Alcantara M , Cravo V , Fazzio L , Felix A , Iso M , Musa C , Siciliano A P , Villaca Filho F , Rodrigues A , Vilela F , Braga J , Silva R , Rodrigues D , Silva L , Morhy S , Fischer C , Silva R , Vieira M , Afonso T , Abreu J , Falcao S N , Moises V A , Gouvea A , Mancuso F J , Souza A C , Silva C Y , João G , Abboud C S , Bellio de Mattos Barretto R , Ramos A , Arnoni R , Assef J E , Della Togna D J , Bihan D Le , Miglioli L , Romero Oliveira A P , Tadeu Magro Kroll R , Cortez D , Gelape C L , Peirira Nunes M d C , De Abreu Ferrari T C , Hay K , Le V , Page M , Poulin F , Sauve C , Serri K , Mercure C , Beaudoin J , Pibarot P , Sebag I A , Rudski L G , Ricafort G , Barsic B , Krajinovic V , Vargovic M , Lovric D , Reskovic-Luksic V , Vincelj J , Jaksic Jurinjak S , Yiannikourides V , Ioannides M , Pofaides C , Masoura V , Pudich J , Linhart A , Siranec M , Marek J , Blechova K , Kamenik M , Pelouch R , Coufal Z , Mikulica M , Griva M , Jancova E , Mikulcova M , Taborsky M , Precek J , Jecmenova M , Latal J , Widimsky J , Butta T , Machacek S , Vancata R , Spinar J , Holicka M , Pow Chon Long F , Anzules N , Bajana Carpio A , Largacha G , Penaherrera E , Moreira D , Mahfouz E , Elsafty E , Soliman A , Zayed Y , Aboulenein J , Abdel-Hay M , Almaghraby A , Abdelnaby M , Ahmed M , Hammad B , Saleh Y , Zahran H , Elgebaly O , Saad A , Ali M , Zeid A , El Sharkawy R , Al Kholy A , Doss R , Osama D , Rizk H , Elmogy A , Mishriky M , Assayag P , El Hatimi S , Hubert S , Casalta J-P , Gouriet F , Arregle F , Cammilleri S , Tessonnier L , Riberi A , Botelho-Nevers E , Gagneux-Brunon A , Pierrard R , Tulane C , Campisi S , Fuzellier J-F , Detoc M , Mehalla T , Boutoille D , Lecompte A S , Lefebvre M , Pattier S , Al Habash O , Asseray-Madani N , Biron C , Brochard J , Caillon J , Cueff C , Tourneau T Le , Lecomte R , Magali Michel M M , Orain J , Delarue S , Bras M Le , Faucher J-F , Aboyans V , Beeharry A , Durox H , Lacoste M , Magne J , Mohty D , David A , Pradel V , Sierra V , Neykova A , Bettayeb B , Elkentaoui S , Tzvetkov B , Landry G , Strady C , Ainine K , Baumard S , Brasselet C , Tassigny C , Valente-Pires V , Lefranc M , Hoen B , Lefevre B , Curlier E , Callier C , Fourcade N , Jobic Y , Ansard S , Berre R Le , Ven F Le , Pouliquen M-C , Prat G , Roux P Le , Bouchart F , Savoure A , Alarcon C , Chapuzet C , Gueit I , Tribouilloy C , Bohbot Y , Peugnet F , Gun M , Duval X , Lescure X , Ilic-Habensus E , Sadoul N , Selton-Suty C , Alla F , Goehringer F , Huttin O , Chevalier E , Garcia R , Marcis V Le , Tattevin P , Flecher E , Revest M , Chirouze C , Bouiller K , Hustache-Mathieu L , Klopfenstein T , Moreau J , Fournier D , Brunel A-S , Lim P , Oliver L , Ternacle J , Moussafeur A , Chavanet P , Piroth L , Salmon-Rousseau A , Buisson M , Mahy S , Martins C , Gohier S , Axler O , Baumann F , Lebras S , Piper C , Guckel D , Börgermann J , Horstkotte D , Winkelmann E , Brockmeier B , Grey D , Nickenig G , Schueler R , Öztürk C , Stöhr E , Hamm C , Walther T , Brandt R , Frühauf A-C , Hartung C T , Hellner C , Wild C , Becker M , Hamada S , Kaestner W , Stangl K , Knebel F , Baldenhofer G , Brecht A , Dreger H , Isner C , Pfafflin F , Stegemann M , Zahn R , Fraiture B , Kilkowski C , Karcher A-K , Klinger S , Tolksdorf H , Tousoulis D , Aggeli C , Sideris S , Venieri E , Sarri G , Tsiapras D , Armenis I , Koutsiari A , Floros G , Grassos C , Dragasis S , Rallidis L , Varlamos C , Michalis L , Naka K , Bechlioulis A , Kotsia A , Lakkas L , Pappas K , Papadopoulos C , Kiokas S , Lioni A , Misailidou S , Barbetseas J , Bonou M , Kapelios C , Tomprou I , Zerva K , Manolis A , Hamodraka E , Athanasiou D , Haralambidis G , Samaras H , Poulimenos L , Nagy A , Bartykowszki A , Gara E , Mungulmare K , Kasliwal R , Bansal M , Ranjan S , Bhan A , Kyavar M , Maleki M , Noohi Bezanjani F , Alizadehasl A , Boudagh S , Ghavidel A , Moradnejad P , Pasha H R , Ghadrdoost B , Gilon D , Strahilevitz J , Wanounou M , Israel S , d'Agostino C , Colonna P , Michele L De , Fumarola F , Stante M , Marchionni N , Scheggi V , Alterini B , Del Pace S , Stefano P , Sparano C , Ruozi N , Tenaglia R , Muraru D , Limbruno U , Cresti A , Baratta P , Solari M , Giannattasio C , Moreo A , Chiara B De , Lopez Montero B , Musca F , Orcese C A , Panzeri F , Spano F , Russo C F , Alfieri O , Bonis M De , Chiappetta S , Del Forno B , Ripa M , Scarpellini P , Tassan Din C , Castiglioni B , Pasciuta R , Carletti S , Ferrara D , Guffanti M , Iaci G , Lapenna E , Nisi T , Oltolini C , Busnardo E , Pajoro U , Agricola E , Meneghin R , Schiavi D , Piscione F , Citro R , Benvenga R M , Greco L , Soriente L , Radano I , Prota C , Bellino M , Vece D Di , Santini F , Salsano A , Olivieri G M , Turrini F , Messora R , Tondi S , Olaru A , Agnoletto V , Grassi L , Leonardi C , Sansoni S , Del Ponte S , Actis Dato G M , Martino A De , Ohte N , Kikuchi S , Wakami K , Aonuma K , Seo Y , Ishizu T , Machino-Ohtsuka T , Yamamoto M , Iida N , Nakajima H , Nakagawa Y , Izumi C , Amano M , Miyake M , Takahashi K , Shiojima I , Miyasaka Y , Maeba H , Suwa Y , Taniguchi N , Tsujimoto S , Kitai T , Ota M , Yuda S , Sasaki S , Hagiwara N , Yamazaki K , Ashihara K , Arai K , Saitou C , Saitou S , Suzuki G , Shibata Y , Watanabe N , Nishino S , Ashikaga K , Kuriyama N , Mahara K , Okubo T , Fujimaki H , Shitan H , Yamamoto H , Abe K , Terada M , Takanashi S , Sata M , Yamada H , Kusunose K , Saijo Y , Seno H , Yuichiro O , Onishi T , Sera F , Nakatani S , Mizuno H , Sengoku K , Park S W , Eun Kyoung K , Ga Yeon L , Hwang J-w , Jin-Oh C , Park S-J , Sang-Chol L , Sung-A C , Jang S Y , Heo R , Lee S , Song J-M , Jung E , Plisiene J , Dambrauskaite A , Gruodyte G , Jonkaitiene R , Mizariene V , Atkocaityte J , Zvirblyte R , Sow R , Codreanu A , Staub T , Michaux C , De la Vega E C L , Jacobs-Orazi L , Mallia Azzopardi C , Xuereb R G , Piscopo T , Farrugia J , Fenech M , Pllaha E , Vella C , Borg D , Casha R , Grib L , Raevschi E , Grejdieru A , Kravcenco D , Prisacari E , Samohvalov E , Samohvalov S , Sceglova N , Panfile E , Cardaniuc L , Corcea V , Feodorovici A , Gaina V , Girbu L , Jimbei P , Balan G , Cardaniuc I , Benesco I , Marian V , Sumarga N , Bozovic B , Bulatovic N , Lakovic P , Music L , Budde R , Wahadat A , Gamela T , Meijers T , Van Melle J P , Deursen V M , Crijns H J , Bekkers S C , Cheriex E C , Gilbers M , Kietselaer B L , Knackstedt C , Lorusso R , Schalla S , Streukens S A , Chamuleau S , Cramer M-J , Teske A , Van der Spoel T , Wind A , Lokhorst J , Liesbek O , Van Heusden H , Tanis W , Van der Bilt I , Vriend J , Lange-van Bruggen H De , Karijodikoro E , Riezebos R , van Dongen E , Schoep J , Stolk V , Offstad J T , Beitnes J O , Helle-Valle T , Skulstad H , Skardal R , Qamar N , Furnaz S , Ahmed B , Butt M H , Khanzada M F , Saghir T , Wahid A , Hryniewiecki T , Szymanski P , Marzec K , Misztal-Ogonowska M , Kosmala W , Przewlocka-Kosmala M , Rojek A , Woznicka K , Zachwyc J , Lisowska A , Kaminska M , Kasprzak J D , Kowalczyk E , Strzecka D F , Wejner-Mik P , Trabulo M , Freitas P , Ranchordas S , Rodrigues G , Pinto P , Queiros C , Azevedo J , Marques L , Seabra D , Branco L , Abreu J , Cruz M , Galrinho A , Moreira R , Rio P , Timoteo A T , Selas M , Carmelo V , Duque Neves B , Pereira H , Guerra A , Marques A , Pintassilgo I , Tomescu M C , Trofenciuc N-M , Andor M , Bordejevic A , Branea H S , Caruntu F , Velcean L A , Mavrea A , Onel M F , Parvanescu T , Pop D , Pop-Moldovan A L , Puticiu M I , Cirin L , Citu I M , Cotoraci C A , Darabantiu D , Farcas R , Marincu I , Ionac A , Cozma D , Mornos C , Goanta F , Popescu I , Beyer R , Mada R , Rancea R , Tomoaia R , Rosianu H , Stanescu C , Kobalava Z , Karaulova J , Kotova E , Milto A , Pisaryuk A , Povalyaev N , Sorokina M , Alrahimi J , Elshiekh A , Jamiel A , Ahmed A , Attia N , Putnikovic B , Dimic A , Ivanovic B , Matic S , Trifunovic D , Petrovic J , Kosevic D , Stojanovic I , Petrovic I , Dabic P , Milojevic P , Srdanovic I , Susak S , Velicki L , Vulin A , Kovacevic M , Redzek A , Stefanovic M , Yeo T C , Kong W K F , Poh K K , Vilacosta I , Ferrera C , Olmos C , Abd El- Nasser M , Calvo Iglesias F , Blanco-Gonzalez E , Bravo Amaro M , Lopez-Rodriguez E , Lugo Adan J , Germinas A N , Pazos-Lopez P , Pereira Loureiro M , Perez M T , Raposeiras-Roubin S , Rasheed Yas S , Suarez-Varela M-M , Vasallo Vidal F , Garcia-Dorado D , Fernandez-Hidalgo N , Gonzalez-Alujas T , Lozano J , Maisterra O , Pizzi N , Rios R , Bayes-Genis A , Pedro Botet L , Vallejo N , Llibre C , Mateu L , Nunez R , Quesada D , Berastegui E , Bosch Portell D , Aboal Vinas J , Albert Bertran X , Brugada Tarradellas R , Loma-Osorio Ricon P , Tiron de Llano C , Arnau M A , Bel A , Blanes M , Osa A , Anguita M , Carrasco F , Castillo J C , Zamorano J L , Moya Mur J L , Alvaro M , Fernandez-Golfin C , Monteagudo J M , Navas Elorza E , Farinas Alvarez M C , Aguero Balbin J , Zarauza J , Gutierrez-Diez J F , Arminanzas C , Arnaiz de las Revillas F , Arnaiz Garcia A , Cobo Belaustegui M , Fernandez Sampedro M , Gutierrez Cuadra M , Garcia Cuello L , Gonzalez Rico C , Rodriguez-Alvarez R , Goikoetxea J , Montejo M , Miro J M , Almela M , Ambrosioni J , Moreno A , Quintana E , Sandoval E , Tellez A , Tolosana J M , Vidal B , Falces C , Fuster D , Garcia-de-la-Maria C , Hernandez-Meneses M , Llopis J , Marco F , Ruiz-Zamora I , Bardaji Ruiz A , Sanz Girgas E , Garcia-Pardo G , Guillen Marzo M , Rodriguez Oviedo A , Villares Jimenez A , Abid L , Hammami R , Kammoun S , Mourali M S , Zghal F Mghaieth , Ben Hlima M , Boudiche S , Ouali S , Zakhama L , Antit S , Slama I , Gulel O , Sahin M , Sade L E , Karacaglar E , Kucukoglu S , Cetinarslan O , Yasar U S , Canpolat U , Mutlu B , Atas H , Dervishova R , Ileri C , Alhashmi J , Tahir J , Zarger P , Baslib F , Woldman S , Menezes L , Primus C , Uppal R , Bvekerwa I , Chandrasekaran B , Kopanska A , Chambers J , Hancock J , Klein J , Rajani R , Ursi M P , Cannata S , Dworakowski R , Fife A , Breeze J , Browne-Morgan M , Gunning M , Streather S , Asch F M , Zemedkun M , Alyavi B , Uzokov J 
Published: April 2019

Abstract

Aims
The European Society of Cardiology (ESC) EURObservational Research Programme (EORP) European Endocarditis (EURO-ENDO) registry aims to study the care and outcomes of patients diagnosed with infective endocarditis (IE) and compare findings with recommendations from the 2015 ESC Clinical Practice Guidelines for the management of IE and data from the 2001 Euro Heart Survey.

Methods and results
Patients (n = 3116) aged over 18 years with a diagnosis of IE based on the ESC 2015 IE diagnostic criteria were prospectively identified between 1 January 2016 and 31 March 2018. Individual patient data were collected across 156 centres and 40 countries. The primary endpoint is all-cause mortality in hospital and at 1 year. Secondary endpoints are 1-year morbidity (all-cause hospitalization, any cardiac surgery, and IE relapse), the clinical, epidemiological, microbiological, and therapeutic characteristics of patients, the number and timing of non-invasive imaging techniques, and adherence to recommendations as stated in the 2015 ESC Clinical Practice Guidelines for the management of IE.

Conclusion
EURO-ENDO is an international registry of care and outcomes of patients hospitalized with IE which will provide insights into the contemporary profile and management of patients with this challenging disease.