bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feasibility and Impact of Community Pharmacy and Novel Pick-up Points for Antiretroviral Therapy Pre-exposure Prophylaxis Initiation and Continuation in Low and Middle-income Countries
Authors: Lalla-Edward Samanta Tresha , Venter Willem Daniel Francois 
Published: November 2024

Abstract
Purpose of Review
This review assesses recent developments in community access to pre-exposure prophylaxis (PrEP) for HIV prevention in low-and middle-income countries (LMICs). It examines literature on differentiated service delivery (DSD) and alternative delivery modes for PrEP, focusing on the role of community pharmacies and novel pick-up points. Key considerations include barriers to access, potential benefits, and strategies for implementation.

Recent Findings
Challenges to optimal HIV healthcare delivery persist globally, with LMICs facing greater barriers due to resource constraints and structural obstacles. Community pharmacies and novel pick-up points offer promising avenues to expand access to HIV medication, especially in hard-to-reach populations. However, operational complexities and regulatory frameworks present significant challenges. Recent initiatives, such as collaborative practice agreements and programmes by global health agencies, highlight efforts to integrate community pharmacies into HIV prevention and care delivery. Mobile health clinics and home delivery services have also shown promise in improving treatment coverage.

Summary
Community pharmacies and novel pick-up points play a crucial role in enhancing access to HIV PrEP in LMICs. Despite challenges related to infrastructure, funding, and regulatory oversight, innovative strategies like DSD and mobile outreach offer opportunities to reach marginalized populations. Real-life examples from LMICs demonstrate the feasibility and effectiveness of leveraging community pharmacies for HIV treatment. However, addressing policy gaps, strengthening pharmacist training, and promoting patient-centred approaches are essential for scaling up access to PrEP. Collaboration between governments, health agencies, and local communities is key to realizing the full potential of community pharmacies in HIV prevention and care.
Social and romantic experiences of banter: perspectives of gay men
Authors: Bickley Oscar E. , Buglass Sarah L. , Betts Lucy R. 
Published: November 2024

AbstractBanter, a form of social communication, is used to facilitate social bonding in friendships and romantic relationships. However, associations between homosocial banter and “lad culture” and potential links to sexual violence and lower wellbeing have highlighted a problematic side to such interactions, especially among males during emerging adulthood. Despite male banter often involving homophobic comments and homosocial behaviour, banter experiences of gay men have to date largely been ignored in the literature. The aim of this study was to explore how gay men in a university setting understand and perceive banter. The data were devised from semi-structured interviews (n = 6, 20–22 years; male). An Interpretative Phenomenological Analysis (IPA) explored the participants’ experiences of banter in their everyday interactions, including within their same-sex friendships and romantic relationships. Themes highlighted how language and behaviours typical of homosocial banter often created a sense of unease when engaging with heterosexual friends, but banter use and perception could be influenced by context and social relationship. Complexities of navigating the ambiguity of banter are discussed.
Nitrogen and Spacing Requirements for Advanced Chipping Selections ND7799c-1 and ND7519-1
Authors: Grow Jed D. , Thompson Asunta L. , Secor Gary A. , Robinson Andrew P. 
Published: November 2024

AbstractAdoption of new cultivars is challenging for commercial growers. To understand the best nitrogen fertilization rate (90, 134, 179, and 224 kg N ha-1) and within-row spacing (15, 23 and 31 cm) for two potential potato cultivar releases from North Dakota State University, a study was carried out in 2019 and 2020 in North Dakota. The advanced chipping selections ND7799c-1 and ND7519-1 were compared to a chip industry standard, Dakota Pearl. In 2019, ND7799c-1 grown at 23 cm within-row spacing had similar marketable yield to Dakota Pearl. In 2020, ND7519-1 at all within-row spacings, and ND7799c-1 at 15 and 23 cm within-row spacing, yielded similarly to Dakota Pearl. Nitrogen rate did not affect yield or chipping quality in 2019 or 2020. The advanced selections had lower sucrose and glucose levels one month after harvest compared to Dakota Pearl in 2020. ND7799c-1 stored for 8 months, and ND7519-1 for 6 months, before chip quality declined. This research demonstrates the potential for ND7799c-1 and ND7519-1 to be successful chip processing cultivars for the Northern Plains.
Comparative enhancement of H+ and OH− treatment on electromagnetic interference shielding in aligned and compact Ti3C2Tx MXene film
Authors: Li Zhao-Yang , Zhao Wei-Jun , Sun Yu , Zhou Bing , Feng Yue-Zhan , Liu Chun-Tai 
Published: November 2024

Abstract
The pressing demand for ultrathin and flexible shields to counter electromagnetic interference (EMI) has sparked interest in Ti3C2Tx MXene materials due to their exceptional electrical conductivity, tunable surface chemistry, and layered structure. However, pure Ti3C2Tx MXene films often lack the mechanical properties required for practical engineering applications, and traditional reinforcement methods tend to reduce electrical conductivity. This work demonstrates an effective strategy to enhance the alignment and densely packed layered structure of Ti3C2Tx MXene films by regulating the acidity and alkalinity of Ti3C2Tx MXene aqueous solutions. This approach simultaneously improves mechanical strength and electromagnetic interference shielding effectiveness (EMI SE). Compared with original Ti3C2Tx MXene films, MXene films modified with ammonia solution (NH3·H2O) via OH− show a significant improvement in tensile strength (27.7 ± 1.9 MPa). Meanwhile, MXene films treated with hydrochloric acid (HCl) via H+ reach an even higher tensile strength of 39 ± 1.5 MPa. Moreover, the EMI SE values of the treated MXene films increase significantly, each reaching 66.2 and 58.4 dB. The maximum improvements in EMI SE values for the acid- and alkali-treated samples are 17.9% and 4%, respectively. In conclusion, the simultaneous enhancement of mechanical strength and EMI shielding efficacy highlights the potential of acid- and alkali-treated Ti3C2Tx MXene films for applications in ultrathin and flexible EMI shielding materials.

Graphical abstract
Simulation of deformation and flow of pulmonary acinus using morphing compared with self-similar deformation
Authors: Maruyama Haruki , Suzuki Yutaro , Miyachi Yoshimasa , Sera Toshihiro , Tanaka Gaku 
Published: November 2024

Abstract
In previous studies of the flow inside the pulmonary acinus, the deformation of acinus was limited because a relatively simple deformation methods, such as self-similar deformation, is used. However, acinus deformation may be complex and heterogeneous. The purpose of this study is to evaluate the influence of the difference in wall deformation between the morphed model and the self-similar deformation model on flow field. The heterogeneous deformation achieved in this study is more actual by using the morphing technology that continuously changes from one shape to another. STAR-CCM + Ver. 13.06 (Siemens PLM Software) was used for numerical calculation, and the governing equations of working fluid are continuous equations and Navier–Stokes equations (NS equations). As a result, the differences in deformation influenced the formation of streamlines at the distal end of the alveolar regions. In the self-similar deformation model, the flow does not change throughout a cycle, whereas in the morphed model, the flow changes during a cycle.

Graphic abstract
Automated scenario generation from Operational Design Domain model for testing AI-based systems in aviation
Authors: Stefani Thomas , Christensen Johann Maximilian , Girija Akshay Anilkumar , Gupta Siddhartha , Durak Umut , Köster Frank , Krüger Thomas , Hallerbach Sven 
Published: November 2024

AbstractApplications based on artificial intelligence (AI) promise benefits, ranging from improved performance to increased capabilities in many industries. In the aviation domain, one example is the new Airborne Collision Avoidance System (ACAS X). The current investigation aims at combining ACAS X and AI to maintain its performance while decreasing the memory footprint. However, the anticipation of AI being increasingly used confronts regulators with challenges in terms of safety assurance and certification. Consequently, the European Union Aviation Safety Agency (EASA) published a concept paper for machine learning applications in aviation. Both, the Concept of Operation (ConOps) in combination with an Operational Design Domain (ODD), are listed as objectives to be met for the safety analysis. From a developer’s perspective, this raises questions on how to effectively derive the ODD from ConOps and test the given system based on the ODD description. Based on an exemplary use case of a Near Mid-Air Collision avoidance between two aircraft through the advisories of ACAS X, a highly automated framework for generating and testing synthetic data is proposed. Using this framework, 1800 Near Mid-Air Collision scenario files are created and automatically executed in the simulation environment FlightGear. Scenario-based testing is used for the logging of ACAS X advisory data and evaluating it against predefined requirements. By this approach, an efficient way of verifying system requirements and conducting automated testing based on the ODD definition is demonstrated. Throughout this process, Model-Based Systems Engineering (MBSE) is used to reduce and manage complexity. The framework in this paper enables a systematic and highly automated approach for scenario generation based on the ODD.
Head Kinematics Associated with Off-Field Head Injury Assessment (HIA1) Events in a Season of English Elite-Level Club Men’s and Women’s Rugby Union Matches
Authors: Allan David , Tooby James , Starling Lindsay , Tucker Ross , Falvey Éanna , Salmon Danielle , Brown James , Hudson Sam , Stokes Keith , Jones Ben , Kemp Simon , O’Halloran Patrick , Cross Matt , Bussey Melanie , Tierney Gregory 
Published: November 2024

Abstract
Objectives
The purpose of this study was to investigate head kinematic variables in elite men’s and women’s rugby union and their ability to predict player removal for an off-field (HIA1) head injury assessment.

Methods
Instrumented mouthguard (iMG) data were collected for 250 men and 132 women from 1865 and 807 player-matches, respectively, and synchronised to video-coded match footage. Head peak resultant linear acceleration (PLA), peak resultant angular acceleration (PAA) and peak change in angular velocity (dPAV) were extracted from each head acceleration event (HAE). HAEs were linked to documented HIA1 events, with ten logistical regression models for men and women, using a random subset of non-case HAEs, calculated to identify kinematic variables associated with HIA1 events. Receiver operating characteristic curves (ROC) were used to describe thresholds for HIA1 removal.

Results
Increases in PLA and dPAV were significantly associated with an increasing likelihood of HIA1 removal in the men’s game, with an OR ranging from 1.05–1.12 and 1.13–1.18, respectively. The optimal values to maximise for both sensitivity and specificity for detecting an HIA1 were 1.96 krad⋅s−2, 24.29 g and 14.75 rad⋅s−1 for PAA, PLA and dPAV, respectively. Only one model had any significant variable associated with increasing the likelihood of a HIA1 removal in the women’s game—PAA with an OR of 8.51 (1.23–58.66). The optimal values for sensitivity and specificity for women were 2.01 krad⋅s−2, 25.98 g and 15.38 rad⋅s−1 for PAA, PLA and dPAV, respectively.

Conclusion
PLA and dPAV were predictive of men’s HIA1 events. Further HIA1 data are needed to understand the role of head kinematic variables in the women’s game. The calculated spectrum of sensitivity and specificity of iMG alerts for HIA1 removals in men and women present a starting point for further discussion about using iMGs as an additional trigger in the existing HIA process.
Some inner metric parameters of a digraph: iterated line digraphs and integer sequences
Authors: Bong N. H. , Dalfó C. , Fiol M. A. , Závacká D. 
Published: November 2024

AbstractIn this paper, we first give a new result characterizing the strongly connected digraphs with a diameter equal to that of their line digraphs. Then we introduce the concepts of the inner diameter and inner radius of a digraph and study their behaviors in its iterated line digraphs. Furthermore, we provide a method to characterize sequences of integers (corresponding to the inner diameter or the number of vertices of a digraph and its iterated line digraphs) that satisfy some conditions. Among other examples, we apply the method to the cyclic Kautz digraphs, square-free digraphs, and the subdigraphs of De Bruijn digraphs. Finally, we present some tables with new sequences that do not belong to The On-Line Encyclopedia of Integer Sequences.
Circulating microRNA panels in subjects with metabolic dysfunction-associated steatotic liver disease after following a 2-year dietary intervention
Authors: Tobaruela-Resola Ana Luz , Riezu-Boj José Ignacio , Milagro Fermín I. , Mogna-Pelaez Paola , Herrero José I. , Elorz Mariana , Benito-Boillos Alberto , Tur Josep A. , Martínez J. Alfredo , Abete Itziar , Zulet María Ángeles 
Published: November 2024

Abstract
Purpose
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) affects one-third of the global population. Despite its high prevalence, there is a lack of minimally non-invasive diagnostic methods to assess this condition. This study explores the potential of circulating microRNAs (miRNAs) as diagnostic biomarkers for MASLD after a 2-year nutritional intervention.

Methods
Fifty-five subjects with steatosis (MASLD group) from the Fatty Liver in Obesity (FLiO) study (NCT03183193) were analyzed at baseline and after 6, 12 and 24 months. Participants were classified into two groups: those who still had steatosis after the intervention (unhealthy group) and those in whom steatosis had disappeared (healthy group). Hepatic status was evaluated through magnetic resonance imaging (MRI), ultrasonography, elastography and serum transaminases. Circulating miRNA levels were measured by RT-PCR.

Results
The dietary intervention was able to modulate the expression of circulating miRNAs after 6, 12, and 24 months. Logistic regression analyses revealed that the most effective panels for diagnosing whether MASLD has disappeared after the nutritional intervention included miR15b-3p, miR126-5p and BMI (AUC 0.68) at 6 months, miR29b-3p, miR122-5p, miR151a-3p and BMI (AUC 0.85) at 12 months and miR21-5p, miR151a-3p and BMI at 24 months (AUC 0.85).

Conclusions
Circulating miRNAs were useful in predicting MASLD in subjects with overweight or obesity after following a weight-loss oriented nutritional intervention. These findings highlight the potential role of miRNAs in diagnosing MASLD and underscore the importance of precision nutrition in managing and determining MASLD.

Clinical trial registration
Trial registration number: NCT03183193 (www.clinicaltrials.gov).
Testing the Goodwin Model: Can Distribution Battles Trigger Business Cycles? Evidence from a Behavioral Experiment
Authors: Conrad Christian A. 
Published: November 2024

AbstractThe Goodwin model provides an important explanation for business cycles with its investment decisions based on pro-cyclical wage fluctuations. The purpose of this paper is to test the central hypothesis of the Goodwin model, namely that wage developments influence investments, which creates business cycles. The model used to test this hypothesis was that of a simplified company, where labor demand is related to investments. Thus, more investments lead to higher wages and vice versa. In the behavioral experiment the test subjects played the manager of a company who maximizes their profits through investments. The central assumptions and conclusions of the Goodwin model are supported by behavioral science.
Implementation of Guidelines for Food and Meals in Kindergartens: Perspectives from Norwegian Kindergarten Staff
Authors: Fjæra Kristin E. , Lekhal Samira , Lekhal Ratib , Helseth Sølvi 
Published: November 2024

Abstract
Establishing dietary food habits in the early years is crucial. Kindergarten is a significant public health arena that can foster healthy eating habits regardless of socioeconomic status. In Norway, 93.4% of children aged 1–5 years attend kindergarten, and since most of their daily food intake is in kindergarten, it is important to make healthy food available. National guidelines on food and meals in kindergartens encourage kindergartens to engage in food and meal practices that promote health, well-being, development, and learning. Despite the guidelines, food and meal practices in kindergartens are highly varied, and implementation of the guidelines is lacking. To understand the challenges in implementing the guidelines, we conducted semi-structured interviews with sixteen staff representing sixteen kindergartens throughout Norway. Both public and private kindergartens were included. All interviews were recorded and transcribed verbatim, and content analysis was performed. The analysis identified three primary themes reflecting staff perceptions of challenges in implementing the national guidelines: priority and structural work with food and meals, pedagogical approach to food and meals, and external expectations and social pressure regarding food and meals. The themes were seen in light of the Consolidated Framework for Implementation Research in the discussion. While external conditions, including municipal prioritization, external expectations, and social pressure, play significant roles, our findings suggest that the most substantial influences on implementation are internal factors, particularly leadership and individual factors.
Zeta Potential of Supercritical CO2‐Water‐Sandstone Systems and Its Correlation With Wettability and Residual Subsurface Trapping of CO2
Authors: Vinogradov Jan , Hidayat Miftah , Sarmadivaleh Mohammad , Vega‐Maza David , Iglauer Stefan , Zhang Lijuan , Mei Dajiang , Derksen Jos 
Published: November 2024

AbstractAlthough CO2 geological storage (CGS) is thought to be one of the most promising technologies to sequester the anthropogenic CO2 to mitigate the climate change, implementation of the method is still challenging due to lack of fundamental understanding of controls of wettability, which is responsible for residual trapping of the gas and its flow dynamics. One of the key parameters that controls the wetting state is the zeta potential, ζ, at rock‐water and CO2‐water interfaces. ζ in systems comprising rocks, carbonated aqueous solutions and immiscible supercritical CO2 have not been measured prior to this study, where we detail the experimental protocol that enables measuring ζ in such systems, and report novel experimental data on the multi‐phase ζ. We also demonstrate for the first time that ζ of supercritical CO2‐water interface is negative with a magnitude greater that 14 mV. Moreover, our experimental results suggest that presence of multi‐valent cations in tested solutions causes a shift of wettability toward intermediate‐wet state. We introduce a new parameter that combines multi‐phase ζ and relative permeability endpoints to characterize the wetting state and residual supercritical CO2 saturation. Based on these results, we demonstrate that ζ measurements could serve as a powerful experimental method for predicting CGS efficiency and/or for designing injection of aqueous solutions with bespoke composition prior to implementing CGS to improve the residual CO2 trapping in sandstone formations.
Increased Asian Sulfate Aerosol Emissions Remarkably Enhance Sahel Summer Precipitation
Authors: Guo Jianing , Xie Xiaoning , Myhre Gunnar , Shindell Drew , Kirkevåg Alf , Iversen Trond , Samset Bjørn H. , Shi Zhengguo , Li Xinzhou , Sun Hui , Liu Xiaodong , Liu Yangang 
Published: November 2024

AbstractObservational evidence shows that Sahel summer precipitation has experienced a considerable increase since the 1980s, coinciding with significant diverging trends of increased sulfate emissions in Asia and decreased emissions in Europe (dipole pattern of aerosols between Asia and Europe). The decrease in European sulfate aerosols has substantial effects on the Sahel summer precipitation increase, but the corresponding effect of increased Asian sulfate is unknown. Multi‐model simulations in the Precipitation Driver and Response Model Intercomparison Project (PDRMIP) show, compared to decreased European aerosols, that increased Asian aerosols similarly enhance the Sahel summer precipitation but with different large‐scale atmospheric circulation changes. Further analysis of the Sixth Coupled Model Intercomparison Project (CMIP6) simulations under historical attribution and various emission scenarios reinforces the results about the climate impacts of anthropogenic aerosols and suggests that in future scenarios with strong international cooperation and rapid climate mitigations (SSP2‐45), the Sahel drought will be intensified likely due to the decline in Asian aerosol emissions. Our results suggest that Asian anthropogenic aerosols are likely a non‐negligible driver of the recent recovery in Sahel precipitation amounts.
The Curvature of TEC as a Proxy for Ionospheric Amplitude Scintillation
Authors: Meziane K. , Hamza A. M. , Jayachandran P. T. 
Published: November 2024

AbstractFluctuations in the ionospheric electron density cause distortions in the Global Navigation Satellite Systems (GNSS) signals recorded on the ground. The examination of these distortions reveal some of the physical conditions under which the electron density fluctuations develop as well as their physical characteristics. Several studies have investigated the correlation between the rate of change of the total electron content and amplitude and phase scintillation indices and , respectively. These studies stipulate that could be used as a proxy for scintillation indices. The link between the scintillation indices and the variations in is investigated both theoretically and empirically. Our study shows that the second derivative (the Laplacian) of the provides a better diagnosis of the nature of the interaction of trans‐ionospheric radio signals with ionospheric irregularities. In the refractive case, the second derivative of fluctuations vanishes. In the diffractive limit, we show that the amplitude scintillation index and the standard deviation of the second derivative of are linearly dependent. The theoretical results are empirically validated with measurements of GNSS radio signals propagating through the auroral ionospheric region and recorded by ground receivers of the Canadian High Arctic Ionospheric Network (CHAIN). The present study suggests that the use of as a proxy for scintillation occurring in the polar and auroral regions must be taken with caution.