bluuebunny/crossref_metadata_2025_split huggingface dataset:
The nitrergic neurotransmission contributes to the anxiolytic‐like effect of Citrus sinensis essential oil in animal models
Authors: Hocayen Palloma de A.S. , Wendler Etiele , Vecchia Débora D. , Kanazawa Luiz K.S. , Issy Ana Carolina , Del Bel Elaine , Andreatini Roberto 
Published: February 2019

Citrus fragrances have been used in aromatherapy for the treatment of anxiety, and the essential oil of Citrus sinensis (sweet orange) has shown promising results, although its mechanism of action was not known. The objective of this study was to evaluate the involvement of nitric oxide (NO) neurotransmission in the anxiolytic‐like effect of C. sinensis essential oil. Swiss male mice were submitted to 15 min of C. sinensis essential oil inhalation (1%, 2.5%, 5%, and 10%) and tested in the marble‐burying test, neophobia‐induced hypophagia, and light/dark test. Locomotor activity was evaluated in an automated locomotor activity box. The coadministration of C. sinensis essential oil with L‐arginine (200 mg/kg, i.p.), an NO precursor, was used for the behavioral evaluation of nitrergic system mediation. Additionally, the NO synthase activity was measured by nicotinamide adenine dinucleotide phosphate diaphorase (NADPH‐d) analysis in the cerebral cortex. C. sinensis essential oil exerted anxiolytic‐like effect at dose that did not change locomotor activity. Moreover, L‐arginine pretreatment prevented this anxiolytic‐like effect on marble‐burying test. Finally, C. sinensis essential oil reduced the NADPH‐d positive cells. Thus, the nitrergic neurotransmission plays a relevant role in the anxiolytic‐like effect C. sinensis essential oil.
Event‐triggered control for a class of strict‐feedback nonlinear systems
Authors: Zhang Cui‐Hua , Yang Guang‐Hong 
Published: February 2019

SummaryThis paper is concerned with the event‐triggered control problem for a class of strict feedback nonlinear networked systems. Different from the existing design methods, a novel user‐adjustable event‐triggered mechanism is first developed to determine the sampling state instants using the negative definite property of the derivatives of Lyapunov functions. Then, an event‐triggered control strategy is devised based on the sampled state vectors and backstepping techniques. It is proved that the proposed control scheme ensures the global convergence of the closed‐loop systems via Lyapunov analyses and the correlation criteria of real variable functions. Finally, two examples are performed to illustrate the effectiveness of the provided control approaches.
Transient organic jams in Puerto Rican mountain streams after hurricanes
Authors: Wohl Ellen , Hinshaw Sarah K. , Scamardo Julianne E. , Gutiérrez‐Fonseca Pablo E. 
Published: February 2019

AbstractExtreme storms in forested environments commonly increase inputs of coarse particulate organic matter (CPOM) and large wood (LW) to streams. Protruding boulders and bedforms, mid‐channel bars, and standing trees can trap CPOM and LW. These organic accumulations can become large enough to span the bankfull channel width, or the accumulations can be predominantly along the channel margins. We refer to both types of accumulations as transient organic jams (TOJs). TOJs can create diverse geomorphic and ecological effects in channel and floodplain environments. We use data collected from mountain streams of the Luquillo Mountains of north‐eastern Puerto Rico following September 2017 Hurricanes Irma and Maria. We examine the location, characteristics, and geomorphic effects of TOJs in channel segments representing diverse drainage areas and channel gradients. We ask three questions: (a) Does the downstream spacing of TOJs correlate with variables such as drainage area or channel gradient? (b) What variables best predict the volume of organic matter within individual TOJs or within a channel segment? And (c) is there a threshold within a river network that separates channel segments with channel‐spanning versus marginal TOJs? Datasets include multiple TOJs along each of 12 stream segments and presence/absence of channel‐spanning TOJs along an additional six streams. Data analysis with multiple linear regressions indicates that downstream spacing, average volume, and total volume per channel length of TOJs correlate significantly with bankfull channel width. Using the akaike information criterion with correction (AICc) model selection method, Strahler stream order has the most influence on the probability of TOJs being marginal or spanning.
Modeling and analysis for multilayered complex communication network of satellite navigation system
Authors: Zhou Wei , Li Qun , Zhu Yi‐fan , He Hua 
Published: February 2019

SummaryThis study is extended to construct the network model, the node model, and the link model of complex communication network for satellite navigation system (CCN‐SNS) based on the hierarchical architecture. Firstly, a method called snapshots was proposed to describe the dynamic topology for CCN‐SNS; secondly, another method was put forward to model the different nodes of the CCN‐SNS; thirdly, the different links between every two different nodes were modeled. Therefore, based on the OPNET tools, a simulation for the CCN‐SNS, which contains the models that proposed earlier used to analyze the navigation accuracy and network transmission performance, was performed.
Auger electron spectroscopic analysis of corrosion products formed on A3003 aluminum alloy in model fresh water with different Zn2+ concentration
Authors: Otani Kyohei , Islam Md. Saiful , Sakairi Masatoshi , Kaneko Akira 
Published: February 2019

The corrosion morphology and composition of corrosion products of A3003 formed in model fresh water with different Zn2+ concentrations were investigated by immersion tests combined with surface observations and analysis using an Auger electron spectroscope (AES). The cross‐sectional AES observations showed that the thickness of the corrosion product layer formed on A3003 decreases with increases in the Zn2+ concentration of the model fresh water. A cross‐sectional AES point analysis suggested that the corrosion products formed on the A3003 in the Zn2+ containing model fresh water (Zn2+ > 0.1 mM) have a multilayered structure and that the inner of Zn‐rich layer would have high corrosion protective properties.
Perspective View on Materialistic, Mechanistic and Operating Challenges of Microbial Fuel Cell on Commercialisation and Their Way Ahead
Authors: Mukherjee Priya , Saravanan Pichiah 
Published: February 2019

AbstractMicrobial fuel cell technology that works on the principle of resource recovery has gained wide popularity among the scientific world. These MFCs were seen as a solution provider for the present day's energy crisis through a non‐traditional sustainable way. Although immense research has marked the development of this system since its innovation, the technology has not competed the commercial implication owing to various associated materialistic and operating limitations. The perspective provides an overview of the various limitations faced that constraints its real‐time application along with perspective solutions.
Synthesis and Optical Properties of Alkaloid Quindoline, Its Structural Analogues and Substituted δ‐Carbolines
Authors: Yu. Shuvalov Vladislav , Rupp Anna S. , Fisyuk Alexander S. , Kuratova Anna K. , Nefedov Andrey A. , Sagitullina Galina P. 
Published: February 2019

AbstractAlkaloid quindoline, its structural analogues and δ‐carbolines were obtained through the Cadogan reaction using DPPE under solvent‐free conditions as a key stage of the synthesis. Various o‐nitroarylpyridines prepared by one‐pot synthesis from nitroacetophenones, methyl orthoformate and acetoacetic ester enamine were used as starting materials for the preparation of δ‐carbolines. 2‐Aryl‐3‐nitro‐5,6,7,8‐tetrahydroquinolines obtained by reacting 2‐hydroxymethylenecyclohexanone with nitroacetophenones enamines were used for the synthesis of quindoline and its structural analogs. A relationship between the structure and optical properties of the synthesized compounds was found.
Additions to Index Herbariorum (Herbaria), Edition 8—Thirteenth Series
Authors: Holmgren Patricia K. , Holmgren Noel H. 
Published: February 2019

AbstractNineteen additional herbaria have been called to our attention since the last installment of this series was published in February 2002. Information on these herbaria is presented below in alphabetical order by country. This brings the total number of herbaria added since the publication of Edition 8 to 393. Information for 3175 herbaria and 9623 people in 165 countries is available for searching by country, institution, city, state, acronym, staff member, correspondent, and research specialty at http://www.nybg.org/bsci/ih/ih.html. Telephone and fax numbers as well as e­mail and URL addresses are included. Note that the Index is fully searchable on research specialty, so it also serves as a PLANT SPECIALISTS INDEX.
Primary Squamous Cell Carcinoma in the Thyroid Gland: A Population‐Based Analysis Using the SEER Database
Authors: Yang Shuwen , Li Cunfu , Shi Xiao , Ma Ben , Xu Weibo , Jiang Hongyi , Liu Wanlin , Ji Qinghai , Wang Yu 
Published: February 2019

AbstractObjectsTo evaluate prognostic factors and treatment outcomes of primary squamous cell carcinoma in thyroid (PSCCTh) over the past decades using a large national database.MethodsAll patients diagnosed with PSCCTh between 1973 and 2015 were identified with the Surveillance, Epidemiology, and End Results Program (SEER) 18‐registry database. Relevant clinical data were collected, and prognostic factors of overall survival (OS) and disease‐specific survival (DSS) were analyzed.ResultsThis cohort study included 242 patients, accounting for 0.12% of all primary thyroid carcinomas from 1973 to 2015 nationwide. Of the patients with PSCCTh, 75% were older than 60 years at diagnosis. Patient age older than 60 years (HR 2.242, 95% CI 1.367–3.676, P = 0.001) and a tumor size larger than or equal to 50 mm (HR 1.479, 95% CI 1.011–2.165, P = 0.044) were independent negative prognostic factors. The univariate analysis suggested that the morphological subtype (OS, P = 0.033; DSS, P = 0.048), clinical treatment modality (OS, P < 0.0001; DSS, P < 0.0001), and T stage (OS, P = 0.004; DSS, P = 0.001) were important predictive factors for OS and DSS. In contrast, gender, race, year of diagnosis, geographic location, N stage, and M stage were not prognostic factors.ConclusionsPSCCTh is a rare malignancy with an aggressive nature and poor prognosis. Survival is predicted by the treatment modality, patient age, T stage, tumor size, and morphological subtypes. This study showed that early diagnosis and complete surgical resection plus adjuvant radiation therapy were associated with a better outcome.
Measurement and Prediction of Phase Transformation Kinetics in a Nuclear Steel During Rapid Thermal Cycles
Authors: Obasi G. , Pickering E. J. , Vasileiou A. N. , Sun Y. L. , Rathod D. , Preuss M. , Francis J. A. , Smith M. C. 
Published: February 2019

Abstract
Accurate prediction of the residual stress distributions in steel welds can only be achieved if consideration is given to solid-state phase transformation behavior. In this work, we assess the ability of a model for reaction kinetics to predict the phase transformations, and corresponding evolution of volumetric strain, in a nuclear pressure vessel steel when subjected to rapid weld-like thermal cycles. The cases under consideration involved the rapid heating of SA508 steel to a temperature of either 900 °C or 1200 °C for a period of 10 seconds, and subsequent cooling of the material to room temperature at rates between 0.1 and 100 °C s−1. Predictions for the microconstituent proportions and transformation temperatures for each thermal cycle are compared to those measured through a combination of dilatometry, optical and electron microscopy, and synchrotron X-ray diffraction. In general, there was good agreement between measured and predicted transformation start temperatures and microconstituent fractions for cooling rates relevant to welding (

$$ \ge $$

≥

10 °C s−1). Even in the cases in which discrepancies were found for start temperatures, examination of the corresponding dilatation curves showed a good match between predicted and experimental transformation strain evolution. This is a very positive result in terms of residual stress prediction in welds. At slower cooling rates, significant discrepancies arose owing to the model’s incapacity to predict Widmanstätten ferrite or retained austenite, and its failure to account for the effects of carbon redistribution during transformations involving diffusion. Although not relevant to welding, improvements to the model to rectify these issues would be beneficial in terms of its wider predictive capabilities.
AN ANALYSIS OF THE MODELS
Authors: ATMAI RACHID 
Published: February 2019

AbstractWe analyze the models $L[T_{2n} ]$, where $T_{2n}$ is a tree on $\omega \times \kappa _{2n + 1}^1 $ projecting to a universal ${\rm{\Pi }}_{2n}^1 $ set of reals, for $n > 1$. Following Hjorth’s work on $L[T_2 ]$, we show that under ${\rm{Det}}\left( {{\rm{}}_{2n}^1 } \right)$, the models $L[T_{2n} ]$ are unique, that is they do not depend of the choice of the tree $T_{2n}$. This requires a generalization of the Kechris–Martin theorem to all pointclasses${\rm{\Pi }}_{2n + 1}^1$. We then characterize these models as constructible models relative to the direct limit of all countable nondropping iterates of${\cal M}_{2n + 1}^\# $. We then show that the GCH holds in $L[T_{2n} ]$, for every $n < \omega $, even though they are not extender models. This analysis localizes the HOD analysis of Steel and Woodin at the even levels of the projective hierarchy.
A prospective observation on nutrition support in adult patients with severe burns
Authors: Guo Fengmei , Zhou Hua , Wu Jian , Huang Yingzi , Lv Guozhong , Wu Yunfu , Zhao Hongsheng , Jin Jun , Zhao Fuli , Liu Lijun , Liu Wenming , Yang Yi , Xu Yuan , Qiu Haibo 
Published: February 2019

AbstractNutrition therapy is considered an important treatment of burn patients. The aim of the study was to delineate the nutritional support in severe burn patients and to investigate association between nutritional practice and clinical outcomes. Severe burn patients were enrolled (n 100). In 90 % of the cases, the burn injury covered above 70 % of the total body surface area. Mean interval from injury to nutrition start was 2·4 (sd 1·1) d. Sixty-seven patients were initiated with enteral nutrition (EN) with a median time of 1 d from injury to first feed. Twenty-two patients began with parenteral nutrition (PN). During the study, thirty-two patients developed EN intolerance. Patients received an average of about 70 % of prescribed energy and protein. Patients with EN providing &lt;30 % energy had significantly higher 28- d and in-hospital mortality than patients with EN providing more than 30 % of energy. Mortality at 28 d was 11 % and in-hospital mortality was 45 %. Multiple regression analysis demonstrated that EN providing &lt;30 % energy and septic shock were independent risk factors for 28- d prognosis. EN could be initiated early in severe burn patients. Majority patients needed PN supplementation for energy requirement and EN feeding intolerance. Post-pyloric feeding is more efficient than gastric feeding in EN tolerance and energy supplement. It is difficult for severe burn patients to obtain enough feeding, especially in the early stage of the disease. More than 2 weeks of underfeeding is harmful to recovery.
Morphological and molecular analyses ofPseudomazocraes sulamericanan. sp.,Pseudomazocraes seleneHargis, 1957,Cemocotyle carangis(MacCallum, 1913) andZeuxapta seriolae(Meserve, 1938) (Monogenea: Mazocraeidea) from carangid fishes in the south-western Atlantic Ocean
Authors: Camargo A.C.A. , Santos C.P. 
Published: February 2019

AbstractAn integrative taxonomy approach was followed to analyse morphological and molecular characters of the monogenean speciesPseudomazocraes selene,Cemocotyle carangisandZeuxapta seriolae; specimens were collected from the gills of the carangid fishesSelene vomer,Caranx latusandSeriola lalandicaught off the coasts of the states of Rio de Janeiro and Santa Catarina, Brazil. The research revealed the presence ofPseudomazocraes sulamericanan. sp., which can be differentiated from other congeners by the shape of clamps mid-sclerite possessing a ventral piece bifurcated at the end, with large and right-angled edges of almost the same length, and by the shape of larval hooks and rounded terminal lappet. New genetic sequences include partial 28S and 18S rDNA genes for all species, ITS1 and 5.8S rDNA forZeuxapta seriolaeandCemocotyle carangis, and ITS2 and mtDNAcox1 forC. carangis. The phylogenetic concatenated analysis based on partial 28S rDNA and 18S rDNA sequences confirmed the position ofC. carangisandZ. seriolaewithin the Heteraxinidae. The previous phylogenetic position of Chauhaneidae was discussed based on morphological studies and it is now confirmed by molecular data that Chauhaneidae is the sister group of Allodiscocotylidae and Protomicrocotylidae.
The verified CakeML compiler backend
Authors: KIAM TAN YONG , MYREEN MAGNUS O. , KUMAR RAMANA , FOX ANTHONY , OWENS SCOTT , NORRISH MICHAEL 
Published: February 2019

AbstractThe CakeML compiler is, to the best of our knowledge, the most realistic verified compiler for a functional programming language to date. The architecture of the compiler, a sequence of intermediate languages through which high-level features are compiled away incrementally, enables verification of each compilation pass at an appropriate level of semantic detail. Parts of the compiler’s implementation resemble mainstream (unverified) compilers for strict functional languages, and it supports several important features and optimisations. These include efficient curried multi-argument functions, configurable data representations, efficient exceptions, register allocation, and more. The compiler produces machine code for five architectures: x86-64, ARMv6, ARMv8, MIPS-64, and RISC-V. The generated machine code contains the verified runtime system which includes a verified generational copying garbage collector and a verified arbitrary precision arithmetic (bignum) library. In this paper, we present the overall design of the compiler backend, including its 12 intermediate languages. We explain how the semantics and proofs fit together and provide detail on how the compiler has been bootstrapped inside the logic of a theorem prover. The entire development has been carried out within the HOL4 theorem prover.
Improper colouring of graphs with no odd clique minor
Authors: Kang Dong Yeap , Oum Sang-Il 
Published: February 2019

AbstractAs a strengthening of Hadwiger’s conjecture, Gerards and Seymour conjectured that every graph with no oddKtminor is (t− 1)-colourable. We prove two weaker variants of this conjecture. Firstly, we show that for eacht⩾ 2, every graph with no oddKtminor has a partition of its vertex set into 6t− 9 setsV1, …,V6t−9such that eachViinduces a subgraph of bounded maximum degree. Secondly, we prove that for eacht⩾ 2, every graph with no odd Kt minor has a partition of its vertex set into 10t−13 setsV1,…,V10t−13such that eachViinduces a subgraph with components of bounded size. The second theorem improves a result of Kawarabayashi (2008), which states that the vertex set can be partitioned into 496tsuch sets.
Limit laws of planar maps with prescribed vertex degrees
Authors: Collet G. , Drmota M. , Klausner L. D. 
Published: February 2019

AbstractWe prove a generalmulti-dimensional central limit theorem for the expected number of vertices of a given degree in the family of planar maps whose vertex degrees are restricted to an arbitrary (finite or infinite) set of positive integersD. Our results rely on a classical bijection with mobiles (objects exhibiting a tree structure), combined with refined analytic tools to deal with the systems of equations on infinite variables that arise. We also discuss possible extensions to maps of higher genus and to weighted maps.
A molecular mechanism of mouse placental spongiotrophoblast differentiation regulated by prolyl oligopeptidase
Authors: Maruyama Yuki , Kimura Atsushi P. 
Published: February 2019

SummaryIn eutherian mammals, the placenta plays a critical role in embryo development by supplying nutrients and hormones and mediating interaction with the mother. To establish the fine connection between mother and embryo, the placenta needs to be formed normally, but the mechanism of placental differentiation is not fully understood. We previously revealed that mouse prolyl oligopeptidase (POP) plays a role in trophoblast stem cell (TSC) differentiation into two placental cell types, spongiotrophoblasts (SpT) and trophoblast giant cells. Here, we focused on SpT differentiation and attempted to elucidate a molecular mechanism. ForAscl2,Arnt, andEgfrgenes that are indispensable for SpT formation, we found that a POP-specific inhibitor, SUAM-14746, significantly decreasedAscl2expression, which was consistent with a significant decrease in expression ofFlt1, a gene downstream ofAscl2. Although this downregulation was unlikely to be mediated by the PI3K-Akt pathway, our results indicated that POP controls TSC differentiation into SpT by regulating theAscl2gene.
Takotsubo cardiomyopathy secondary to non-accidental trauma presenting as an “unwitnessed” arrest
Authors: Serrano Ryan M. , Schamberger Marcus , Parent John J. 
Published: February 2019

AbstractTakotsubo cardiomyopathy is characterised by akinesis and ballooning of the left ventricular apex during contraction of the otherwise normal base of the heart. We describe the case of a 7-month-old previously healthy female who presented with an unwitnessed cardiac arrest. Workup raised suspicion for non-accidental trauma. Despite progression to brain death, the severely decreased ventricular function and apical akinesis of the left ventricle improved within 40 hours of admission. This report will familiarise paediatricians with this rare cardiomyopathy and emphasise the importance of considering non-accidental trauma as an inciting event for patients with unwitnessed cardiac arrest found to have decreased ventricular function.
Atrioventricular valves dysplasia in a newborn
Authors: Melo Manuel , Garcia Torres Enrique , Boni Lorenzo 
Published: February 2019

AbstractA newborn with prenatally diagnosed dysplasia of both atrioventricular valves presented after birth with signs and symptoms of low cardiac output, severe regurgitation of both mitral and tricuspid valves. This combination is as rare as challenging, since it regards both the timing and management of this complex cardiac malformation. We report an early surgical repair of both atrioventricular valves in a symptomatic newborn, which improved his clinical status and, so far, delayed valve replacement.