bluuebunny/crossref_metadata_2025_split huggingface dataset:
1,8-cineol attenuated Aβ25-35-induced neuron injury through inhibiting IL-6, IL-8 release and NF-κB expression
Authors: Lu Changliang , Wang Lin , Wang Shumei , Li Wanzhong , Li Haijian , Sun Lin , Shi Wenzhen , Zhao Chunzhen 
Published: February 2019

Objective: To explore the protective effect of 1,8-cineol against Amyloid beta25-35 ( Aβ25-35)-induced cell injury in primary rat cortical neurons.
Methods: Primary rat cortical neurons were cultured in vitro, treated with different concentrations of Aβ25-35 (2.5, 5, 10 20, 40 μM) and 1,8-cineol (1, 3, 10 μM). Cell viability of neuronal cells were detected by MTT assay and cell death were detected by lactate dehydrogenase release (LDH). The production of IL-6 and IL-8 in the supernatant were measured by ELISA assay kits. NF-κB protein expression was detected by Western blotting.
Results: In primary cultured neurons, Aβ25-35 concentration dependently reduced cell viability and increased LDH release. 1,8-cineol with concentrations of 3 and 10 μM protected neuronal cells against Aβ25-35 induced cell injury for 24 h. 3 and 10 μM of 1,8-cineol also significantly decreased the levels of IL-6 and IL-8 cytokine production in the supernatant. Increased NF-κB expression was also significantly reduced by 1,8-cineol treatment evaluated by Western blotting.
Conclusions: Our results revealed a protective effect of 1,8-cineol on Aβ25-35 induced neuron injury through inhibition of IL-6, IL-8 production and NF-κB expression.
Karakterisasi Morfologi dan Potensi Hasil Durian Lokal Bangka
Authors: Mustikarini Eries Dyah , Khodijah Nyayu Siti , Yulistia Yulistia 
Published: February 2019

Durian adalah tanaman yang mudah mengalami erosi genetik. Eksplorasi dan karakterisasi harus dilakukan untuk melindungi plasma nutfah durian lokal Bangka.Penelitian ini bertujuan untuk karakterisasi morfologi, menentukan hubungan kekerabatan dan potensi hasil aksesi durian lokal Bangka. Penelitian dilaksanakan bulan Desember 2011 sampai Februari 2012 di Kabupaten Bangka Barat, Bangka Tengah dan Bangka Selatan. Penelitian terbagi dalam kegiatan yaitu ekplorasi, identifikasi dan karakterisasi. Berdasarkan hasil eksplorasi didapatkan 11 aksesi berasaldari bangka barat, 7 aksesi dari bangka selatan dan lima aksesi dari bangka tengah. 23 aksesi yang didapatkan mengelompok membentuk 5 kelompok pada tingkat kesamaan 60%. Potensi hasil rata-rata buah durian lokal Bangka mencapai 40-250 buah/tahun. Durian dengan potensi hasil tertinggi adalah aksesi Sigajah dengan rata-rata berat buah 2.3 kg dan hasil 60-140 buah/pohon.
Selection of Bangka Local Rice Accession by Variability and Heritability Test
Authors: Prayoga Gigih Ibnu , Mustikarini Eries Dyah , Pradika Desti 
Published: February 2019

Selection of parent plant is the first step in hybridization activities. The parent plant usually come from germplasms because it has a high diversity and good potential. Testing the potential of germplasm can be done by variability and heritability test. The purpose of this research was to selection of parent plant for plant breeding activity based on the value of variability and heritability. The research was conducted at the Experimental Garden of Faculty of Agriculture, Fisheries, and Biology, Bangka Belitung University. The research used experimental methods by was Randomized Block Design (RBD) with 3 blocks. The treatment are 7 accessions is Grintil, Balok Runti, Mukud Besak, Mayang Curui, Payang Tebing, Balok Lutong and Balok Lukan Jintan. The results showed that there were character differences between 7 local rice accessions of Bangka. The 7 local rice accessions of Bangka have high heritabilities value on The results showed that there were character differences between 7 local rice accessions of Bangka. The 7 local rice accessions of Bangka have high heritabilities values for plant height, flowering time, long panicle, total empty grain, harvest time, long seed, seed width, weight of 1000 seeds, total seeds, and weight seed/plant. Wide variability was found in long seed character. Balok Runti and Payak Tebing were recommended as the parent plants for further breeding activities.
Development Analysis of Global Competitiveness Index of ASEAN-7 Countries and Its Relationship on Gross Domestic Product
Authors: Nababan Tongam Sihol 
Published: February 2019

The objectives of the research are: (1) to investigate the development of global competitiveness index (GCI) of ASEAN-7 countries as an illustration of economic performance and potentiality, (2) to investigate which factors or pillars are drivers for the improvement of GCI ASEAN-7 countries, and (3) to analyze the effect of Gross Domestic Product (GDP) on GCI of ASEAN-7 countries. The analysis method used in calculating the weight of the contribution of each pillar to changes in the competitiveness index, and determining the effect of GDP on GCI, a Semi-Logarithmic Regression analysis is used. The result shows that during the period of year 2008/2009 to the year of 2016/2017, the rank and index of GCI of each ASEAN-7 countries continue to increase. The pillars of the basic requirement subindex still dominate the largest contribution to the improvement of the competitiveness index for Indonesia, Philippines, Thailand, Cambodia, and Vietnam. As for Malaysia and Singapore sub-indexes of efficiency enhancers and innovation-sophistication have been able to give the largest contribution to the improvement of GCI. The GDP of ASEAN-7 countries has a positive and significant impact on the improvement of global competitiveness index, except for Thailand. The most problematic factors in improving the competitiveness index are corruption, inadequately educated labour, access to financing, tax regulations, and inefficient government bureaucracy.
İran-Irak Savaşı’nda Kullanılan İran Propaganda Posterlerinin Göstergebilimsel Analizi
Authors: ÇAKI Caner 
Published: February 2019

İran-Irak
Savaşı, dünya tarihindeki en kanlı savaşlardan biri olmuştur. 22 Eylül 1980
yılında Irak Devlet Başkanı Saddam Hüseyin önderliğinde Irak Ordusu'nun İran
sınırını geçmesiyle başlayan savaş, 20 Ağustos 1988 yılında ilan edilen ateşkes
ile son bulmuştur. Savaşın sonunda her
iki taraftan yüz binlerce kişi hayatını kaybetmiştir. İran Devrimi'nden bir yıl
sonra meydana gelen savaşta İran, halkını Irak Ordusu'na karşı seferber ederken
yoğun bir propaganda faaliyetine yürüttü. Özellikle bu savaşta İran, kamuoyunda
Irak'a karşı destek bulabilmek için propaganda amaçlı posterleri etkin bir
şekilde kullandı. Bu çalışmada, İran-Irak Savaşı'nda kullanılan propaganda
amaçlı posterler içerisinden Chicago Üniversitesi tarafından belirlenen 8
propaganda afişi, nitel araştırma yöntemleri içerisinde yer alan
göstergebilimsel analiz yöntemine tabi tutularak incelemiştir. Posterlerin
göstergebilimsel analizi Fransız Dil Bilimci Roland Barthes'ın düzanlam,
yananlam ve mit kavramları ışığında yapılmıştır. Elde edilen bulgular ışığında,
İran'ın, ABD ve Irak'a karşı nefret söylemi inşa ederek İran halkını Irak
Ordusu'na karşı seferber etmeye çalıştığı görülmüştür.
COMPARATIVE ANALYSIS OF DATA ON THE DURATION OF FIRE EXPOSURE BEFORE REACHING THE CRITICAL TEMPERATURE STEEL OBTAINED FOR SAMPLES STANDARDIZED AND SAMPLE SIZE REDUCTION FROM FIREPROOF MATERIALS "ENDOTERM 400202" AND "ENDOTERM 210104"
Authors: Novak S , Drizhd V , Dobrostan O 
Published: February 2019

The results of the determination of the convergence of experimental data on the duration of fire exposure under the standard temperature regime until the critical temperature of steel obtained for standardized samples (columns) and samples of reduced sizes (plates) with the use of the reactive fireproof material "Endoterm 400202", flowing under the thermal influence in fire conditions, and passive fireproof material (plates) «Endoterm 210104». It has been established that the deviation of the values of the duration of fire exposure to achievement the critical temperature of steel, determined for samples of reduced sizes, from the experimental data obtained on standardized samples, is, on average,–9,5% and 4,7% for reactive and passive fireproof materials, respectively. In this case, for a reactive fireproof material the value of this deviation is in the range from -24,0 % to 17,6 %, and most of it (93 %) has negative values (the duration of fire exposure until the critical temperature of steel, determined for most samples reduced sizes does not exceed the experimental data obtained for standardized samples). For a passive fireproof material, the values of deviation are in the range from -24,7 % to 23,1 %, and most of them (75 %) have positive values (the duration of fire exposure until the critical temperature of steel, determined for most samples of reduced sizes, exceeds the experimental data obtained for standardized samples). The average deviation is 12,1 % and 10,8 %, respectively, for reactive and passive fireproof materials. A regularity is established regarding the dependence of the deviation value of the critical temperature of steel. For a reactive fireproof material, with a increase of the critical temperature from 350 °C to 450 °C (and in some samples – up to 500 °C or more) the deviation decreases. With a further increase of this temperature, the deviation increases (up to temperature of 650 °C), and then decreases. For a passive fireproof material with an increase of the critical temperature from 350 °C to 500 °C (and in some samples – up to 550 °C or more) the deviation increases. With a further increase of this temperature the value of the deviation decreases.
ORGANIZATION OF MEASURES ON EVACUATION IN THE CASE OF THREAT AND CONDUCT OF MILITARY OPERATIONS. PROBLEMS AND WAYS OF THEIR DECISION
Authors: Fomin A , Sliusar A 
Published: February 2019

Protection of the population from the negative impact of the consequences of man-made, natural and military emergencies is a priority task of all governmental authorities, including local authorities, as well as heads of economic objects, regardless of ownership forms. The solution of this issue requires an integrated approach, which involves the implementation of a number of measures for the creation of protective structures, providing the population with personal protective equipment, preparing population for emergencies, timely alert and informing about the threat or emergency, evacuation of the population and other measures. One of the main ways of protecting the population in the case of an immediate threat to life and causing damage to the population health remains timely, organized by the removal the population from the zones of possible influence of negative factors of emergency of man-made, natural or military character and placing it outside of the zones of action the damaging factors of the sources of emergency, that is, their evacuation. At the same time, this method is quite complicated, requiring careful preparation of all authorities and the serious training of all citizens in the conduct of evacuation. The practice of organizing and conducting evacuation of the population from the anti-terrorist operation (ATO) zone in the Donetsk and Lugansk regions has revealed a number of problems on this issue.
The article provides an analysis and defines the problems of the organization of protection of the population at the threat and occurrence of emergencies caused by the use of weapons, including measures on population evacuation from areas of warfare to safe areas. Approaches to organizing and conducting mass evacuation in NATO member states are considered. The analysis of requirements established in Ukraine for the evacuation of the population and the experience of their practical implementation at the beginning and during the military conflict in eastern Ukraine, as well as caused by explosions in ammunition depots, was carried out. The results of the analysis identified the problems that arose during the evacuation of the population and suggested ways to solve them
EMERGENCY PREPAREDNESS AND RESPONSE IN CASE OF RADIATION ACCIDENT
Authors: Kalynenko L , Kymakovska N 
Published: February 2019

In Ukraine the activities aimed at prevention of radioactive accidents are conducted on a high level. Among these, a system of preparedness and emergency response is of great importance.
This work describes the experience of collaboration of central executive authorities, functional and territorial subsystems of general state civil protection system and operating organizations within the framework of the system of preparedness and emergency response to radiation and nuclear accidents. This is done for popularization and using of this experience in other spheres of man-made safety.
An important aspect of management of radiation emergencies is the ability to respond immediately and adequately, that is, emergency response. This requires is to identify the response strategy in accordance with the dynamic of the situation, namely: needs in organizing protective measures, actions for protection the population and emergency personnel, using of all available information for the assessment of radiation situation.
Emergency Response is defined by IAEA as implementation of measures aimed at reducing the disaster consequences for human health and safety and environment. It can also provide the basis for renovation of normal social and economic activity.
Accidents with radioactive sources or materials are a broad category, including a source found or radioactive material, contaminated areas or objects, unprotected sources, accidents in laboratories, on industrial or scientific facilities, as well as transport accidents.
In case of nuclear or radiation emergency on the operating nuclear stations of Ukraine, central and local authorities should, in accordance with the local legislation, make decisions and act based on the existing institutional and territorial plans, taking into consideration the recommendations of IAEA and operating organization, as well as regulations of other responsible institutions.
The data of analysis identified that priority and prospective tasks of functioning and development of the system of Emergency preparedness and response to radiation accidents in Ukraine are prevention and liquidation of nuclear and/or radiation accidents.
A Patient with Intermediate Syndrome with Toxic Encephalopathy Following Organophosphate Poisoning
Authors: Sharif Mohiuddin , Bhuiyan Muktadir , Roy Rajib , Haque Mahfuzul , Amin Md Robed 
Published: February 2019

OP poisoning is the common cause of mortality and morbidity in Bangladesh. Although acute cholinergic crisis is the common form of presentation of such cases, the intermediate syndrome and delayed encephalopathy can be also presented in op compound. A 14 year old adolescent presented with acute onset of intermediate syndrome and simultaneous early encephalopathy after ingestion of combination of Chlorpyrifos with Cypermithrin known popularly as market name of ‘Mortar’. The patient was provided supportive care and few days of ICU care with complete recovery. The interesting feature of the case was absence of cholinergic crisis and hence patient was not treated with atropine or pralidoxime.The simultaneous combination of presenting features, prolonged coma and even on absence of specific antidote complete recovery was the highlighting points of this unique case.
Bangladesh J Medicine Jan 2019; 30(1) : 41-43
Effect of Curcuma longa (Turmeric) on serum creatine kinase-MB and troponin I in isoproterenol induced myocardial infarction in wistar albino rats
Authors: Nahar Sharmin , Akhter Qazi Shamima 
Published: February 2019

Background: The prevalence of myocardial infarction (MI) is increasing day by day in Bangladesh due to socioeconomic transition. Spices and herbs are important source of remedy for various diseases in human. Curcuma longa suggested to be used as an indigenous medicine for the prevention and treatment of cardiovascular disease.
Objective: To observe the effect of Curcuma longa in isoproterenol induced myocardial infarction in Wistar albino rats.
Methods: This experimental study was carried out in the Department of Physiology, Dhaka Medical College, Dhaka during 2015. Twenty one Wistar albino male rats, weighing 100 to 150 g (initial body weight); aged 85 to 100 days were selected for the study. After acclimatization for 14 days, the rats were divided into BC (Baseline control group), ISP-TC (Isoproterenol treated control group) and CLP-ISPT (Curcuma longa pretreated and isoproterenol treated group). Each group consisted of 7 rats. After experiment, on the 10th day, final body weight was taken, rats were sacrificed and blood samples were collected from the heart. The heart was removed and weighed. Serum creatine kinase-MB (CK-MB) level was estimated by ELISA method and Troponin I (cTnI) level by AxSYM method. The statistical analysis was done by one way ANOVA and Bonferroni test as applicable.
Results: In this study, the mean percent (%) change of body weight (p<0.01), mean serum CK-MB (p<0.001) and cTnI (p<0.001) levels were significantly higher but mean heart weight was non significantly higher in ISP-TC in comparison to those of BC. Again, the mean percent (%) change of body weight (p<0.01), mean heart weight (p<0.01), mean serum CK-MB (p<0.01) and cTnI (p<0.001) levels were significantly lower in CLP-ISPT than those of ISP-TC group.
Conclusion: From the results, it can be concluded that Curcuma longa may have cardioprotective effect.
J Bangladesh Soc Physiol. 2018, December; 13(2): 47-53
Serum calcium and serum phosphate levels in transfusion dependent beta thalassemia
Authors: Sultana Mst Ariza , Akhter Qazi Shamima 
Published: February 2019

Background: Patients with transfusion dependent beta thalassemia with severeanemia require regular blood transfusion to improve quality of life. This can lead to iron overload which might cause various complications including hypocalcaemia.
Objective: To estimate the serum calcium and phosphate levels in transfusion dependent beta thalassemia patients.
Methods: This cross-sectional study was conducted in the Department of Physiology, Dhaka Medical College, Dhaka from July 2016 to June 2017. After fulfilling the ethical aspect, a total number of 60 subjects were selected with the age ranging from 5 to 25 years. Among them, 40 transfusion dependent beta thalassemia patients were selected as the study group and 20 age and sex matched apparently healthy individuals were considered as control group for comparison. The study population were selected from Thalassemia foundation hospital, Dhaka. Theserum calcium and phosphate levels were estimated by autoanalyzer.. For statistical analysis, unpaired Student’s‘t’ test, Chi-square test were performed as applicable.
Results: In this study, serum calcium level were significantly (p < 0.001) lower and serum phosphate level were significantly (p < 0.001) higher in transfusion dependent beta thalassemia patients as compared to healthy controls. In addition, 67.5% thalassemia patients had hypocalcemia (calcium level < 8.5 mg/dl) and 85% of thalassemia patients had hyperphosphatemia(phosphate level > 4.7mg/dl).
Conclusions: This study concludes transfusion dependent beta thalassemiapatients have low calcium level and high serum phosphate level which should be monitored to avoid complications related to hypocalcaemia and hyperphosphatemia.
J Bangladesh Soc Physiol. 2018, December; 13(2): 54-58
The effect of fish oil capsule on serum total cholesterol and triglycride levels in type-2 diabetic patient
Authors: Habib Tamanna Binte , Akhter Qazi Shamima 
Published: February 2019

Background: Diabetes Mellitus (DM) is one of the common metabolic disorders that have effects on lipid metabolism. Fish oil supplementation may improve lipid abnormalities in diabetic patient.Objective: To observe the effect of supplementation of omega-3 fatty acid on total cholesterol (TC) and triglyceride(TG) level in type 2 DM.
Methods: A prospective interventional study was conducted from January 2017 to December 2017. A total numbers of 52 diagnosed type 2 diabetic patients of both sexes were selected with age 40 to 50 years. Among them, 27 type 2 diabetic patient with supplementation of omega 3 fatty acid (2g/ day) for 12 weeks was considered as study group. Another 25 type 2 diabetic patients without supplementation of omega 3 fatty acid was considered as control group. The study subjects were selected from Outpatient Department of Endocrinology, Dhaka Medical College Hospital, Dhaka and personal contact from Dhaka city.Serum TC and TG were estimated by enzymatic endpoint method in autoanalyzer. The study parameters were measured at base line and after 12 weeks of study period in both groups. For statistical analysis, Paired Student’s‘t’ test and Unpaired Student’s ‘t’ test were performed as applicable using SPSS for windows version 16.0.
Results: In this study serumTC and TG levels were significantly lower (p<.001) in diabetic patients after supplementation with omega- 3 fatty acid in comparison to that of their baseline value.Again, after 12 weeks, serum TC and TG levels were significantly lower (p<.001) in diabetic patients after supplementation with omega-3 fatty acid in comparison to control group. In control group, serum TC and TG levels were almost similar both at baseline and after 3 months of follow-up.
Conclusion: After analyzing the results of the study, it can be concluded that omega-3 fatty acid may improve serum TC and TG levels in type 2 diabetic patient and may be helpful to minimize the complications of type-2 DM.
J Bangladesh Soc Physiol. 2018, December; 13(2): 73-77
Um olhar psicopedagógico sobre o ensino das operações de multiplicação e divisão de números naturais proposto do 1º ao 3º ano nos Livros Didáticos dos anos iniciais do ensino fundamental
Authors: Almeida Márcia Santos Melo , Aredes Alaíde Pereira Japecanga 
Published: February 2019

O objetivo desse artigo, é investigar a proposta de ensino das operações de multiplicação e divisão de números naturais no bloco referente à Alfabetização Matemática em uma coleção de livros didáticos aprovada pelo PNLD/2013, anos iniciais do ensino fundamental. Para tanto, foi pensado trazer um olhar psicopedagógico voltado para o ensino de Matemática, pautado ainda em algumas teorias de aprendizagem de PIAGET (1998) e VIGOTSKY (1998), acerca das concepções de aprendizagem de ambos. A escolha desse tema foi feita a partir da busca da compreensão de como se dá o ensino dessas operações nesse nível de ensino. Em meio as análises da proposta de ensino por uma coleção de livros didáticos, são trazidas discussões que remetem a reflexões acerca da formação do professor desse nível de ensino. Os resultados das análises mostram que a proposta de ensino das operações de multiplicação e divisão de números naturais no bloco referente à Alfabetização Matemática coaduna com os documentos oficiais em relação às sugestões de ensino nos níveis investigados.
A filosofia da educação como problematizadora e reflexiva na formação docente
Authors: Bezerra Leonardo Mendes , Carvalho Ana Cristina Teixeira de Brito , Maldaner Laíra de Cássia Barros Ferreira 
Published: February 2019

Este artigo objetivou analisar a percepção dos egressos do curso de Letras da Universidade Estadual do Maranhão, Campus Balsas, sobre o componente curricular "Filosofia da Educação" na formação docente. A concepção das relações entre o pensar e o fazer pedagógico nas aulas de Filosofia da Educação pode ser um diferencial na formação docente. Metodologicamente, utilizou-se a pesquisa analítica e explicativa com auxílio da aplicação de questionários. O público foi selecionado pela amostra aleatória, sendo incluídos especialmente aqueles que atuavam na educação básica. A análise de conteúdo quantitativa e qualitativa sintetizou as principais categorias reveladas na pesquisa, a saber: 1. Filosofia da Educação: problematização e reflexão sobre as questões educacionais; 2. Pensamento crítico-reflexivo educacional no aspecto filosófico; 3. A constituição dos valores humanos na formação do cidadão. Diante disso, constatou-se que a disciplina proporcionou aos egressos subsídios para as ações problematizadoras, reflexivas e críticas sobre as questões pedagógicas de modo radical, rigorosa e de conjunto, conforme os preceitos propalados por Saviani.