bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE CRAB AS COSMIC YUX: A SYMBOL OF POWER AND CREATION IN COTZUMALHUAPA
Authors: Moreira Fernando A. 
Published: May 2019

AbstractCrab iconography in Mesoamerica is a novelty, often ignored academically while its meaning remains a mystery. In Cotzumalhuapa, the crab appears as either a base or a headdress in monumental art, but why? Why is the crab singled out in the creation portion of thePopol Vuh, establishing an unexplained precedent? The following work attempts to answer these questions. The decapod itself was not arbitrarily chosen for its role aspaxil, or as a feminine symbol of creation, with links to the moon and rain. Rather, its biology and behavior mirrored the existing Mesoamerican worldview. Unfortunately, the linguistic and cultural affinities of Cotzumalhuapa are unknown. Thus, I analyze other objects from other regions/cultures and compares zoological, linguistical, and ethnohistorical data to conclude that the crab was conceptually feminine, a cognate to the moon goddess and the surface of the earth, representing creation. Furthermore, rulers of Cotzumalhuapa wore regalia that include crab imagery, which provided them the power of creation and propagated belief in the legitimacy of their rule.
Different Words, Same Song: Advice for Substantively Interpreting Duration Models
Authors: Jones Benjamin T. , Metzger Shawna K. 
Published: May 2019

ABSTRACTThe use of duration models in political science continues to grow, more than a decade after Box-Steffensmeier and Jones (2004). However, several common misconceptions about the models still persist. To improve scholars’ use and interpretation of duration models, we point out that they are a type of regression model and therefore follow the same rules as other more commonly used regression models. In this article, we present four maxims as guidelines. We survey the various duration model interpretation strategies and group them into four categories, which is an important organizational exercise that does not appear elsewhere. We then discuss the strengths and weaknesses of these strategies, noting that all are correct from a technical perspective. However, some strategies make more sense than others for nontechnical reasons, which ultimately informs best practices.
The Effects of Radiation and Sex Differences on Adaptive Functioning in Adult Survivors of Pediatric Posterior Fossa Brain Tumors
Authors: Panwala Tanya F. , Fox Michelle E. , Tucker Tiffany D. , King Tricia Z. 
Published: May 2019

AbstractObjective: Radiation therapy (RT) improves rates of survival of patients with childhood brain tumors but increases deficits in cognition and independent living skills. Previous literature has studied difficulties in basic cognitive processes, but few explore impairment in higher-order skills such as adaptive functioning. Some studies identify females as at risk for cognitive deficits due to RT, but few investigate sex differences in adaptive functioning. It was hypothesized that females would exhibit poorer long-term independent living skills and core cognitive skills relative to males following RT. Methods: Forty-five adult survivors of posterior fossa childhood brain tumors (24 females) completed the Wechsler Abbreviated Scale of Intelligence (WASI-II), Wechsler Memory Scale, Third Edition (WMS-III) Digit Span Forward (DSF) and Backward (DSB), and Oral Symbol Digit Modalities Test (OSDMT). Informants completed the Scales of Independent Behavior-Revised (SIB-R). Results: DSF and OSDMT were positively correlated with all five SIB-R domains, full-scale IQ (FSIQ) was positively correlated with four SIB-R domains, and DSB was positively correlated with three SIB-R domains. There was an interaction between sex and RT for OSDMT and community living skills with trend level interactions for personal living skills and broad independent living skills, where females without RT had higher scores than females with RT. Conclusions: Female survivors were more affected by RT than males across the community living skills domain of adaptive functioning as well as processing speed. Processing speed deficits may have a cascading impact on daily living skills. Future studies should investigate how clinical and biological factors may contribute to personalized treatment plans between sexes. (JINS, 2019, 25, 729–739)
Relationship between mid-upper arm circumference and BMI for identifying maternal wasting and severe wasting: a cross-sectional assessment
Authors: Kumar Praveen , Sinha Rajesh , Patil Narendra , Kumar Virendra 
Published: May 2019

AbstractObjective:To assess the strength of correlation and agreement between mid-upper arm circumference (MUAC) and BMI, and determine suitable MUAC cut-offs, to detect wasting and severe wasting among non-pregnant adult women in India.Design:Cross-sectional studies were conducted in five high-burden pockets of four Indian states.Setting:Prevalence of malnutrition among women and children is very high in these pockets and the government plans to implement community-based pilot projects to address malnutrition in these areas.Participants:Anthropometric measurements were carried out on 1716 women with children &lt;5 years of age. However, analyses were conducted on 1538 non-pregnant adult women.Results:The results showed a strong correlation between MUAC and BMI in the non-pregnant women, with correlation coefficient of 0·860 (95 % CI 0·831, 0·883;P&lt; 0·001). Cohen’sκof 0·812 and 0·884 also showed good agreement between MUAC and BMI in identifying maternal wasting and severe wasting, respectively. The univariate regression model between MUAC and BMI explained 0·734 or 73 % of the variation in BMI. The MUAC cut-offs for wasting (BMI &lt; 18·5 kg/m2) and severe wasting (BMI &lt; 16·0 kg/m2) were calculated as 232 and 214·5 mm, respectively.Conclusions:MUAC is a strong predictor of maternal BMI among non-pregnant women with children &lt;5 years in high-burden pockets of four Indian states. In a resource-constrained setting where BMI may not be feasible, the MUAC cut-offs could reliably be used to screen wasting and severe wasting in non-pregnant women for providing appropriate care.
CONSTANCY OF NEWTON POLYGONS OF -ISOCRYSTALS ON ABELIAN VARIETIES AND ISOTRIVIALITY OF FAMILIES OF CURVES
Authors: Tsuzuki Nobuo 
Published: May 2019

AbstractWe prove constancy of Newton polygons of all convergent$F$-isocrystals on Abelian varieties over finite fields. Applying the constancy, we prove the isotriviality of proper smooth families of curves over Abelian varieties. More generally, we prove the isotriviality over projective smooth varieties on which any convergent$F$-isocrystal has constant Newton polygons.
Resistance of different host plants and cultivars of cassava to the mealybug Phenacoccus manihoti: Effect of infestation on leaf extract composition
Authors: Tertuliano M. , Rü B. Le 
Published: May 2019

AbstractThe effect of a 2-month infestation by the cassava mealybug (Phenacoccus manihoti Mat. Ferr.) on the metabolism of nitrogen (amino acids) and carbon (carbohydrates), leaf area and total dry weight of five cassava varieties (Manihot esculenta Crantz), faux-caoutchouc (a hybrid of M. esculenta and M. glaziovii Muell, Arg.), poinsettia (Euphorbia pulcherrima Wild) and talinum (Talinum triangulare Jack) was studied. Free amino acid and free sugar contents as well as relative free amino acid composition in the leaf extracts, although found to be very different from one plant to another, were not significantly modified by P. manihoti infestation, except for the total amino acid contents of the cassava variety 30M7. Variations in one particular amino acid induced by mealybug infestation were not linked to the antibiotic resistance of these plants. Infestation by the cassava mealybug did not modify the total dry weight but reduced the total leaf area although this reduction was only significant in cassava varieties 59M2, 30M7 and M'pembe, and in faux-caoutchouc. Within the genus Manihot, the reduction in leaf area was strongly correlated (r= -0.878, P≤0.05) to the degree of antibiotic resistance and was coupled to an increase in the ratio of sugars to amino acids, suggesting a similarity between the effects of water stress and those of mealybug infestation.
Impact of the groundnut leafminer, Aproaerema modicella (Deventer) (Lepidoptera: Gelechiidae) on growth and yield of two groundnut cultivars
Authors: Shanower T.G. , Gutierrez A.P. , Wightman J.A. 
Published: May 2019

AbstractThe impact of larval defoliation by Aproaerema modicella (Deventer) on the growth, development and yield of two groundnut cultivars (Kadiri 3 and NC Ac 17090) was studied under a naturally occurring, high density infestation. Defoliation by leaf-mining larvae did not increase plant mortality in either cultivar. In both cultivars, leaf and stem production were significantly lower in untreated plots than in the treated plots. Unsprayed plants of both cultivars produced fewer flowers, pegs, and pods per plant compared to plants of the same cultivar protected with monocrotophos. Fruit growth rates, however, were marginally higher in control plots than in treated plots. Pod yields were 35 and 44% lower, and haulm yields 25 and 20% lower, in Kadiri 3 and NC Ac 17090, respectively in untreated control plots compared to plots treated with insecticide. A linear relationship between leafminer density and pod and haulm yields was observed, and differences between cultivars were not significant.
Association between Salivary Alpha-Amylase and Executive Functioning in Healthy Children
Authors: Maldonado Enrique F. , Nislin Mari , Marín Laura , Martín-Escribano Ana , Enguix Alfredo , López Cristina , Magarín Alba , Álamo Ana , Ortíz Paula , Muñoz Marina , García Silvia 
Published: May 2019

AbstractThe main aim of this study was to confirm the relationship between executive performance and salivary alpha-amylase (SAA) activity in a sample of 64 healthy children (39 boys), and compare it to the association of SAA output and salivary flow rate (SFR). Executive functioning was assessed viafluency, trail-making, ringsandinhibitiontasks from the Batería de Evaluación Neuropsicológica de la Función Ejecutiva en Niños [Battery of Neuropsychological Assessment for Executive Function in Children] (ENFEN), merged into an ENFEN total score. SAA activity, output, and SFR were measured at baseline, one minute before, and one minute after the end of a neuropsychological testing session. Our results confirmed a direct, linear and significant association between SAA activity and executive functioning,r(64) = .351,p< .05, and extended it to SAA output,r(64) =.431,p< .05. The mean level of SAA output was the best predictor of executive functioning (β = .431,p< .05) and explained 18.2 % of the variance in ENFEN total score. In sum, and compared to SAA activity, measuring SAA output may be a more precise and indirect marker to assess executive functioning in children.
Common carpetgrass (Axonopus fissifolius) control with POST herbicides
Authors: Henry Gerald , Johnston Christopher , Hoyle Jared , Straw Chase , Tucker Kevin 
Published: May 2019

AbstractReductions in MSMA use for weed control in turfgrass systems may have led to increased common carpetgrass infestations. The objective of our research was to identify alternative POST herbicides for control of common carpetgrass using field and controlled-environment experiments. Field applications of MSMA (2.2 kg ai ha−1) and thiencarbazone + iodosulfuron + dicamba (TID) (0.171 kg ai ha−1) resulted in the greatest common carpetgrass control 8 wk after initial treatment (WAIT): 94% and 91%, respectively. Thiencarbazone + foramsulfuron + halosulfuron (TFH) (0.127 kg ai ha−1) applied in the field resulted in 77% control 8 WAIT, whereas all other treatments were ≤19% effective at 8 WAIT. All treatments resulted in greater common carpetgrass control when applied in the greenhouse. Applications of MSMA, TFH, and TID resulted in the highest common carpetgrass control in the greenhouse 8 WAIT: 94%, 94%, and 91%, respectively. Control with nicosulfuron (0.035 kg ai ha−1) and trifloxysulfuron (0.028 kg ai ha−1) (81% and 75%, respectively) was greater in the greenhouse than observed in the field 8 WAIT. Sequential applications of foramsulfuron (0.058 kg ai ha−1) resulted in only ≤11% common carpetgrass control 8 WAIT, regardless of application site. All herbicide treatments in the greenhouse resulted in reduced aboveground common carpetgrass biomass 8 WAIT compared to the nontreated control (12.9 g). Aboveground biomasses of common carpetgrass in response to MSMA, TID, TFH, nicosulfuron, and trifloxysulfuron were 1.6 to 2.1 g, regardless of treatment. Reduced efficacy of foramsulfuron was reflected in greater biomass (4.7 g) in response to treatments. Thiencarbazone + iodosulfuron + dicamba may be an alternative to MSMA for common carpetgrass control; however, long-term assessment may be warranted to evaluate treatment effectiveness. Further investigation into application timing may be necessary to enhance the efficacy of TFH for the control of common carpetgrass.
Multiple herbicide-resistant horseweed (Conyza canadensis) dose response to tolpyralate and tolpyralate plus atrazine and comparison to industry standard herbicides in corn
Authors: Metzger Brendan A. , Soltani Nader , Raeder Alan J. , Hooker David C. , Robinson Darren E. , Sikkema Peter H. 
Published: May 2019

AbstractHorseweed biotypes resistant to glyphosate and ALS-inhibiting herbicides are becoming more prevalent in Canada and the United States and present a significant management challenge in field crops. Tolpyralate is a recently commercialized herbicide for use in corn that inhibits 4-hydroxyphenylpyruvate dioxygenase (HPPD), and there is little information regarding its efficacy on horseweed. Six field experiments were conducted in 2017 and 2018 at four locations in Ontario, Canada, to determine the biologically effective dose of tolpyralate and tolpyralate + atrazine and to compare label rates of tolpyralate and tolpyralate + atrazine to currently accepted herbicide standards for POST control of glyphosate and cloransulam-methyl resistant (MR) horseweed. At 8 wk after application (WAA), tolpyralate at 4.8 and 22.6 g ha–1provided 50% and 80% control, respectively. When applied with atrazine at a 1:33.3 tank-mix ratio, 22.3 + 741.7 g ha–1provided 95% control of MR horseweed. The addition of atrazine to tolpyralate at label rates improved control of MR horseweed to 98%, which was similar to the control provided by dicamba:atrazine and bromoxynil + atrazine. The results of this study indicate that tolpyralate + atrazine provides excellent control of MR horseweed POST in corn.
Controls on the Transport of Meltwater From the Southern Greenland Ice Sheet in the Labrador Sea
Authors: Castelao Renato M. , Luo Hao , Oliver Hilde , Rennermalm Asa K. , Tedesco Marco , Bracco Annalisa , Yager Patricia L. , Mote Thomas L. , Medeiros Patricia M. 
Published: May 2019

AbstractCoastal waters in the Labrador Sea are influenced by the seasonal input of meltwater from the Greenland ice sheet, which is predicted to more than double by the end of the century. Mechanisms controlling the offshore export of meltwater can have a significant effect on stratification and vertical stability in the Labrador Sea, being particularly important if the meltwater is transported toward the interior of the basin where winter convection occurs. Here we use a high‐resolution ocean model to show that coastal upwelling winds play a critical role transporting the meltwater offshore to about 150 km from the coast, where increased eddy activity and mean circulation can then transport the meltwater farther offshore. While meltwater discharged from West Greenland is either transported to Baffin Bay or circumnavigates the basin flowing mostly along isobaths, meltwater from East Greenland can reach the interior of the basin where it may influence stratification and winter convection whenever winds are anomalously upwelling favorable in late summer and early fall.
Early Cenozoic Decoupling of Climate and Carbonate Compensation Depth Trends
Authors: Greene S. E. , Ridgwell A. , Kirtland Turner S. , Schmidt D. N. , Pälike H. , Thomas E. , Greene L. K. , Hoogakker B. A. A. 
Published: May 2019

AbstractOur understanding of the long‐term evolution of the Earth system is based on the assumption that terrestrial weathering rates should respond to, and hence help regulate, atmospheric CO2 and climate. Increased terrestrial weathering requires increased carbonate accumulation in marine sediments, which in turn is expected to result in a long‐term deepening of the carbonate compensation depth (CCD). Here, we critically assess this long‐term relationship between climate and carbon cycling. We generate a record of marine deep‐sea carbonate abundance from selected late Paleocene through early Eocene time slices to reconstruct the position of the CCD. Although our data set allows for a modest CCD deepening, we find no statistically significant change in the CCD despite >3 °C global warming, highlighting the need for additional deep‐sea constraints on carbonate accumulation. Using an Earth system model, we show that the impact of warming and increased weathering on the CCD can be obscured by the opposing influences of ocean circulation patterns and sedimentary respiration of organic matter. From our data synthesis and modeling, we suggest that observations of warming, declining δ13C and a relatively stable CCD can be broadly reproduced by mid‐Paleogene increases in volcanic CO2 outgassing and weathering. However, remaining data‐model discrepancies hint at missing processes in our model, most likely involving the preservation and burial of organic carbon. Our finding of a decoupling between the CCD and global marine carbonate burial rates means that considerable care is needed in attempting to use the CCD to directly gauge global carbonate burial rates and hence weathering rates.
Computational strategies for design and discovery of nanostructured thermoelectrics
Authors: Hao Shiqiang , Dravid Vinayak P. , Kanatzidis Mercouri G. , Wolverton Christopher 
Published: May 2019

AbstractThe contribution of theoretical calculations and predictions in the development of advanced high-performance thermoelectrics has been increasingly significant and has successfully guided experiments to understand as well as achieve record-breaking results. In this review, recent developments in high-performance nanostructured bulk thermoelectric materials are discussed from the viewpoint of theoretical calculations. An effective emerging strategy for boosting thermoelectric performance involves minimizing electron scattering while maximizing heat-carrying phonon scattering on many length scales. We present several important strategies and key examples that highlight the contributions of first-principles-based calculations in revealing the intricate but tractable relationships for this synergistic optimization of thermoelectric performance. The integrated optimization approach results in a fourfold design strategy for improved materials: (1) a significant reduction of the lattice thermal conductivity through multiscale hierarchical architecturing, (2) a large enhancement of the Seebeck coefficient through intramatrix electronic band convergence engineering, (3) control of the carrier mobility through band alignment between the host and second phases, and (4) design of intrinsically low-thermal-conductivity materials by maximizing vibrational anharmonicity and acoustic-mode Gruneisen parameters. These combined effects serve to enhance the power factor while reducing the lattice thermal conductivity. This review provides an improved understanding of how theory is impacting the current state of this field and helps to guide the future search for high-performance thermoelectric materials.
Reduced FcRn-mediated transcytosis of IgG2 due to a missing Glycine in its lower hinge
Authors: Stapleton Nigel M. , Brinkhaus Maximilian , Armour Kathryn L. , Bentlage Arthur E. H. , de Taeye Steven W. , Temming A. Robin , Mok Juk Yee , Brasser Giso , Maas Marielle , van Esch Wim J. E. , Clark Mike R. , Williamson Lorna M. , van der Schoot C. Ellen , Vidarsson Gestur 
Published: May 2019

AbstractNeonatal Fc-receptor (FcRn), the major histocompatibility complex (MHC) class I-like Fc-receptor, transports immunoglobuline G (IgG) across cell layers, extending IgG half-life in circulation and providing newborns with humoral immunity. IgG1 and IgG2 have similar half-lives, yet IgG2 displays lower foetal than maternal concentration at term, despite all known FcRn binding residues being preserved between IgG1 and IgG2. We investigated FcRn mediated transcytosis of VH-matched IgG1 and IgG2 and mutated variants thereof lacking Fc-gamma receptor (FcγR) binding in human cells expressing FcRn. We observed that FcγR binding was not required for transport and that FcRn transported less IgG2 than IgG1. Transport of IgG1 with a shortened lower hinge (ΔGly236, absent in germline IgG2), was reduced to levels equivalent to IgG2. Conversely, transport of IgG2 + Gly236 was increased to IgG1 levels. Gly236 is not a contact residue between IgG and FcRn, suggesting that its absence leads to an altered conformation of IgG, possibly due to a less flexible Fab, positioned closer to the Fc portion. This may sterically hinder FcRn binding and transport. We conclude that the lack of Gly236 is sufficient to explain the reduced FcRn-mediated IgG2 transcytosis and accounts for the low maternal/fetal IgG2 ratio at term.
A universal transcriptomic signature of age reveals the temporal scaling of Caenorhabditis elegans aging trajectories
Authors: Tarkhov Andrei E. , Alla Ramani , Ayyadevara Srinivas , Pyatnitskiy Mikhail , Menshikov Leonid I. , Shmookler Reis Robert J. , Fedichev Peter O. 
Published: May 2019

AbstractWe collected 60 age-dependent transcriptomes for C. elegans strains including four exceptionally long-lived mutants (mean adult lifespan extended 2.2- to 9.4-fold) and three examples of lifespan-increasing RNAi treatments. Principal Component Analysis (PCA) reveals aging as a transcriptomic drift along a single direction, consistent across the vastly diverse biological conditions and coinciding with the first principal component, a hallmark of the criticality of the underlying gene regulatory network. We therefore expected that the organism’s aging state could be characterized by a single number closely related to vitality deficit or biological age. The “aging trajectory”, i.e. the dependence of the biological age on chronological age, is then a universal stochastic function modulated by the network stiffness; a macroscopic parameter reflecting the network topology and associated with the rate of aging. To corroborate this view, we used publicly available datasets to define a transcriptomic biomarker of age and observed that the rescaling of age by lifespan simultaneously brings together aging trajectories of transcription and survival curves. In accordance with the theoretical prediction, the limiting mortality value at the plateau agrees closely with the mortality rate doubling exponent estimated at the cross-over age near the average lifespan. Finally, we used the transcriptomic signature of age to identify possible life-extending drug compounds and successfully tested a handful of the top-ranking molecules in C. elegans survival assays and achieved up to a +30% extension of mean lifespan.