bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumer-led experience customization: a socio-spatial approach
Authors: Torres Edwin N. , Lugosi Peter , Orlowski Marissa , Ronzoni Giulio 
Published: March 2018

Purpose
Adopting a socio-spatial approach, this study develops a consumer-centric conception of service experience customization. In contrast to existing service customization research, which has focused on company-centric approaches, the purpose of this paper is to examine the practices through which consumers use, abuse, subvert, transform, or complement organizational resources to construct their consumption experiences.

Design/methodology/approach
The empirical context for this study is a Meetup group: a consumer network organized around members’ shared interests and activities in theme parks. The research utilized participant observation of members’ face-to-face activities during two years and over 80 events, interviews with key informants, and content analysis of online interactions.

Findings
The findings outline how consumers interact across physical and virtual spaces utilizing technologies and material objects. The data are used to propose a new consumer-centric conceptualization of experience customization, distinguishing between three modes: collaborative co-production, cooperative co-creation, and subversive co-creation.

Originality/value
It is argued that the three modes of customization provide a way to understand how consumers mobilize and (re)deploy organizational resources to create experiences that may complement existing service propositions, but may also transform them in ways that challenge the service provider’s original goals and expectations. Furthermore, this study identifies the factors that shape which modes of customization are possible and how they are enacted. Specifically, the discussion examines how experiential complexity, governability, the compatibility of consumer and organizational practices, and the collective mobilization of resources may determine the scope and form of customization.
Towards understanding social innovation in multicultural societies
Authors: de Bruin Anne , Read Christine 
Published: March 2018

Purpose
The purpose of this paper is to argue, using the New Zealand context as reference, that heterogeneous societies with diverse cultures have an expanded space of possibilities for developing social innovations.

Design/methodology/approach
Incorporation of the cultural context is integral to finding innovative, collective solutions for mitigating complex social problems and sparking transformational social change. Empirical support for this contention draws on examples of social innovations that embed the cultural values of Māori, New Zealand’s indigenous people.

Findings
Using illustrative cases, the authors highlight the capacity of Māori values, encompassed in an ecosystem of Māori social institutions, to catalyse social innovation in New Zealand. The authors position these examples within two paradigms of social innovation.

Research limitations/implications
The paper limits its focus to the implications of Māori cultural values for social innovation. However, it serves to highlight that appreciation of indigenous and minority cultural values can provide a foundation for social innovations in other contexts too.

Practical implications
Recognising cultural values increases the range of possibilities for innovatively addressing social and environmental challenges.

Social implications
Respect and recognition of indigenous culture and knowledge offers potential for sustainable solutions to complex social challenges.

Originality/value
This is one of the few papers to explore the cultural embeddedness of social innovation and highlight public policy social innovations.
Reflections on the theme issue outcomes
Authors: Dornier Raphaël , Mauri Chiara , Teare Richard 
Published: March 2018

Purpose
The aim of this paper is to profile the World Hospitality and Tourism Themes (WHATT) theme issue “Tourism sustainability in the Alpine region: What are the major trends and challenges?” with reference to the experience of the theme editors and writing team.

Design/methodology/approach
This paper uses structured questions to enable the theme editors to reflect on the rationale for the theme issue question, the starting-point, the selection of the writing team and material and the editorial process.

Findings
It draws on a multidisciplinary approach to identify some key components of sustainable tourism for the French and Italian Alps. It reflects on research and stakeholder interaction that helped to shape the current and future thinking about how Alpine mountain resorts can enhance sustainability in relation to the destination offer, accommodation, transport and mobility and institutional, legal and socio-economic aspects.

Practical implications
The theme issue outcomes provide lines of enquiry for others to explore, and they reinforce the value of WHATT’s approach to collaborative working and writing.

Originality/value
The work reported in this theme issue provides research-based evidence of the need for rapid adaptation to sustainable tourism development for resorts in the French and Italian Alps. Traditionally designed to facilitate skiing and snow sports, the impact of climate change is forcing a rethink to safeguard Alpine tourism – a vital economic activity to these and most mountain tourism destinations.
The great crossing of the Alps or move your Alps (GTA)
Authors: Leroux Erick 
Published: March 2018

Purpose
The purpose of this study is to highlight the Grande Traversée des Alpes or – Move your Alps (GTA) which can be regarded as one of the first organizations to promote sustainable tourism in the Alps.

Design/methodology/approach
The study is based on a case study of the GTA.

Findings
The GTA is a key case study for understanding stakeholders’ management and sustainable tourism in the Alps.

Originality/value
There has been insufficient attention given in the literature to the role of the GTA, especially given its importance in the promotion of sustainable tourism in the Alps.
Inaccurate Conception: ACB v Thomson Medical
Authors: Foxton Tom 
Published: March 2018

AbstractThis note considers the decision of the Singapore Court of Appeal in ACB v Thomson Medical in which the plaintiff sought damages for the upkeep costs of a child conceived using sperm from someone other than her husband as a result of negligence by a fertility clinic. The Court held that upkeep costs could not be recovered as a matter of public policy, but recognised a new head of loss, namely damages for loss of genetic affinity. In a controversial ruling, the Court quantified these damages at thirty per cent of the upkeep costs of the child. While holding that punitive damages could be recovered outside the categories recognised in Rookes v Barnard, the Court rejected such an award on the facts of the case.
Urban Politics as the Unfolding of Social Relations in Place: The Case of Sexually Transmitted Disease Investigation in Mid‐Twentieth‐Century Gay Seattle
Authors: Knopp Larry , Brown Michael , Mckeithen Will 
Published: March 2018

AbstractRecent debates in urban politics stress the need to broaden conceptions of what counts as urban politics, as well as of where they take place. This means shifting attention to include more quotidian and prosaic social relations, including those taking place in spaces of civil society. We answer this call with a case study of the relations between an emerging gay male community in mid‐twentieth‐century Seattle, USA and the local public health department’s disease investigators (DIs). We focus on both the biopolitics and cultural politics of the investigation process, from the perspectives of both DIs and gay men. We point out certain tensions and paradoxes in these processes as a form of governmentality, and interpret them through a ‘noir’ cultural lens that is consistent with a notion of urban politics as the unfolding of social relations in place. We conclude by stressing how our findings and framework can augment urban political inquiry both intellectually and empirically.
Sperm limitation affects sex allocation in a parasitoid wasp Nasonia vitripennis
Authors: Chirault Marlène , Bressac Christophe , Goubault Marlène , Lécureuil Charlotte 
Published: March 2018

AbstractInsect reproduction is influenced by various external factors including temperature, a well‐studied constraint. We investigated to what extent different levels of sperm limitation of males exposed to different heat stresses (34 and 36 °C) affect females’ offspring production and sex allocation in Nasonia vitripennis. In this haplodiploid parasitoid wasp attacking different species of pest flies, we investigated the effect of the quantity of sperm females received and stored in their spermatheca on their sperm use decisions, hence sex allocation, over successive ovipositions. In particular, we compared the sex allocation of females presenting three levels of sperm limitation (i.e., mated with control, 34 °C heat‐stressed or 36 °C heat‐stressed males) on each host they parasitized. To disentangle the potential reduction of sperm quality after a heat stress exposure from that of sperm quantity, we also explored the clutch size and sex ratio produced by females that were partially sperm limited after copulating with multiply mated males. Independently of their sperm numbers, all types of females produced a similar total number of offspring, but the more limited ones had fewer daughters. Sperm limitation further affected the distribution of daughters’ production across time. In addition to constraints acting on female physiology, male fertility should therefore be considered in studies measuring reproductive outputs of insects submitted to heat stresses.
Empirical metronidazole for patients with severe bacterial infection: protocol for a systematic review
Authors: Petersen M. W. , Perner A. , Bahador M. , Sjövall F. , Møller M. H. 
Published: March 2018

IntroductionAnaerobic bacteria are believed to be common pathogens in severe infections. Yet, they are difficult to culture and consequently often unrecognised in clinical infections. Metronidazole is often used empirically for potential anaerobic infections, as the resistance to metronidazole is low. However, disadvantages of metronidazole use exist, including drug interactions, side effects and economical expenses. Currently, the balance between the benefits and harms of empirical metronidazole for severe bacterial infections is unknown.We aim to assess patient‐important benefits and harms of empirical metronidazole vs. placebo or no treatment in adult patients with severe bacterial infection of any origin in a systematic review of randomised clinical trials with meta‐analysis and trial sequential analysis.Methods and analysisThis protocol provides details on the planned systematic review, which will be prepared according to the Preferred Reporting Items for Systematic Reviews and Meta‐analyses (PRISMA) statement, the Cochrane Handbook, and the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) criteria. The primary outcome is all‐cause mortality. Secondary outcomes include adverse events, secondary infections, use of life support, antibiotic resistance and hospital length of stay. We will conduct conventional meta‐analyses, including predefined subgroup‐ and sensitivity analyses. Additionally, we will assess the risk of random errors by trial sequential analysis.Ethics and disseminationEthical approval is not needed, as the outlined review exclusively will include previously published data. We aim to publish in an international, peer‐reviewed journal.
Audit committee characteristics and financial statement comparability
Authors: Endrawes Medhat , Feng Zhuoan , Lu Meiting , Shan Yaowen 
Published: March 2018

AbstractFinancial statement comparability enables weighing the similarities and differences in financial performance between firms. Prior studies mainly focus on the role of accounting standards in the production of comparability, but the role of economic agents has been largely overlooked. We find that a firm's audit committee size and financial expertise affect its financial statement comparability. Financial information tends to be more comparable among industry peers when audit committees are larger and more members have financial and accounting expertise. The effect of audit committee expertise on comparability is stronger for firms with less independent and smaller boards, for firms with non‐Big 4 auditors and for firms with CEOs serving as the chairperson of the boards.
The effects of the selective muscarinic M3 receptor antagonist darifenacin, and of hyoscine (scopolamine), on motion sickness, skin conductance & cognitive function
Authors: Golding John F. , Wesnes Keith A. , Leaker Brian R. 
Published: March 2018

AimsThe aim of this study was to compare the effects of the selective M3 muscarinic acetylcholine receptor antagonist darifenacin, oral hyoscine hydrobromide and placebo on motion sickness induced by cross‐coupled stimulation.MethodsThe effects of darifenacin 10 mg or 20 mg, hyoscine hydrobromide 0.6 mg and placebo were assessed in a randomized, double‐blind, four‐way cross over trial of 16 healthy subjects. Motion sickness, skin conductance (a measure of sweating) and psychomotor cognitive function tests were investigated.ResultsHyoscine hydrobromide produced significantly increased tolerance to motion versus placebo (P < 0.05 to P < 0.01). The motion protection effect of darifenacin (10 or 20 mg) was approximately one third that of hyoscine hydrobromide but was not significant versus placebo. Darifenacin and hyoscine hydrobromide both significantly reduced skin conductance versus placebo. Darifenacin produced either no effect or an enhanced effect on cognitive function in contrast to hyoscine hydrobromide, where there was significant impairment of psychomotor performance.ConclusionThe results suggest that selective antagonism of the M3 receptor may not be important in the prevention of motion sickness. However, selective M3 antagonism does not impair cognitive function. These observations may be important given that long‐term treatment with non‐selective anti‐muscarinic agents such as oxybutynin may lead to an increased incidence of dementia.
Preventability of serious thromboembolic and bleeding events related to the use of oral anticoagulants: a prospective study
Authors: Sennesael Anne‐Laure , Larock Anne‐Sophie , Devalet Bérangère , Mathieux Valérie , Verschuren Franck , Muschart Xavier , Dalleur Olivia , Dogné Jean‐Michel , Spinewine Anne 
Published: March 2018

AimsTo determine the preventability of serious adverse drug reactions (ADRs) related to the use of direct oral anticoagulants (DOACs), and to explore contributing factors to preventable ADRs. Results were compared with vitamin K antagonists (VKAs).MethodsWe conducted a prospective observational study in the emergency departments of two teaching hospitals from July 2015 to January 2016. Patients admitted with a thrombotic or bleeding event while under DOAC or VKA were included. Four independent reviewers assessed causality, seriousness and preventability of ADRs using pilot‐tested scales. For cases of serious and potentially preventable ADRs, we performed semi‐structured interviews with general practitioners to identify contributing factors to ADRs. The primary outcome was the proportion of serious ADRs that were potentially preventable.ResultsThe analysis included 46 DOAC and 43 VKA patients (median age 79 years). Gastrointestinal (n = 34) and intracranial (n = 16) bleedings were the most frequent ADRs. Results were that 53% of DOAC‐ and 61% of VKA‐related serious ADRs were deemed potentially preventable. Prescribing issues and inadequate monitoring were frequent for DOAC and VKA respectively. We identified many causes of preventable ADRs that applied to all oral anticoagulants, such as pharmacodynamic drug interactions and lack of communication.ConclusionsMore than half of serious ADRs were potentially preventable for both DOACs and VKAs. Interventions focusing on prescribing, patient education and continuity of care should help improve the use of DOACs in practice.
Reproductive organ‐sparing cystectomy significantly improves continence in women after orthotopic bladder substitution without affecting oncological outcome
Authors: Gross Tobias , Furrer Marc , Schorno Petra , Wuethrich Patrick Y. , Schneider Marc P. , Thalmann George N. , Burkhard Fiona C. 
Published: March 2018

ObjectivesTo compare functional and oncological outcomes of reproductive organ‐sparing cystectomy (ROSC) compared with standard cystectomy (SC) in women undergoing orthotopic bladder substitution (OBS).Patients and MethodsBetween 1995 and 2016, 121 consecutive women undergoing OBS were prospectively included in this single‐centre non‐randomized clinical follow‐up study comprising an ROSC and an SC group. Urinary continence, the need for intermittent self‐catheterization (ISC), lateral standing micturition cystourethrogram (MCUG), urethral pressure profile findings, if available, and oncological outcomes were assessed and compared between ROSC and SC.ResultsAfter 12 months, patients who had undergone ROSC with OBS had significantly higher daytime and nighttime continence rates than patients who had undergone SC with OBS (87.5% vs 63.5%; P = 0.027 and 87.5% vs 57.7%; P = 0.008), whereas no significant differences were found between groups in ISC rates (12.5% vs 12.94%; P > 0.99). The degree of attempted nerve‐sparing (none, unilateral, bilateral) positively affected continence rates in both groups. No significant differences were found in local recurrence rates (0% vs 9.4%; P = 0.126), 5‐ and 10‐year overall survival rates (80.9% and 80.9% vs 64.9% and 55.7%; P = 0.443) or 5‐ and 10‐year cancer‐specific survival rates (84.3% and 84.3% vs 73% and 66.2%; P = 0.431).ConclusionSuperior continence rates were found for ROSC with an OBS compared with SC, without a negative impact on oncological outcome. ROSC should, therefore, be offered to women receiving an OBS whenever justifiable.
Experimental design and analysis and their reporting II: updated and simplified guidance for authors and peer reviewers
Authors: Curtis Michael J , Alexander Steve , Cirino Giuseppe , Docherty James R , George Christopher H , Giembycz Mark A , Hoyer Daniel , Insel Paul A , Izzo Angelo A , Ji Yong , MacEwan David J , Sobey Christopher G , Stanford S Clare , Teixeira Mauro M , Wonnacott Sue , Ahluwalia Amrita 
Published: March 2018

AbstractThis article updates the guidance published in 2015 for authors submitting papers to British Journal of Pharmacology (Curtis et al., 2015) and is intended to provide the rubric for peer review. Thus, it is directed towards authors, reviewers and editors. Explanations for many of the requirements were outlined previously and are not restated here. The new guidelines are intended to replace those published previously. The guidelines have been simplified for ease of understanding by authors, to make it more straightforward for peer reviewers to check compliance and to facilitate the curation of the journal's efforts to improve standards.
A novel treatment for height growth in patients with growth hormone insensitivity syndrome by cyproheptadine hydrochloride
Authors: Razzaghy‐Azar Maryam , Nourbakhsh Mitra , Nourbakhsh Mona 
Published: March 2018

SummaryBackgroundCyproheptadine HCl (CyproH) is an appetite‐stimulating drug and while it was prescribed for a patient with growth hormone insensitivity syndrome (GHIS) for increasing appetite, his height growth was surprisingly increased. Therefore, the aim of this study was to investigate the effect of CyproH on growth parameters of the patients with GHIS.Patients and designTwenty patients were enrolled in two prospective cohorts at two different times. Fifteen cases were observed for 1.17 ± 1.3 years without treatment (observation period, OP). Then, CyproH was administered for 2.2 ± 2.7 years (treatment period, TP), and growth parameters were compared within these two periods. Five patients who did not receive any treatment for 1‐8.24 years (4 ± 2.9) were the control group.ResultsHeight velocity (HV) increased from 1.88 ± 0.7 to 6.1 ± 0.8 cm/year and HV‐SDS reached from −4.5 ± 0.74 to −0.21 ± 1.2 in OP and TP, respectively (P < .001), whereas HV and HV‐SDS were 2.2 ± 1.1 cm/yr and −4.2 ± 1.2, respectively, in controls (P < .001). Height SDS was −7.0 ± 1.7 and increased to −6 ± 2.2 after treatment (P = .002). Gain in height was 2.3 ± 0.6 SDS in 5 patients who were treated for 5.4 ± 2.8 years. BMI‐SDS was not significantly changed within two time periods and also in cases and controls.ConclusionCyproH caused height growth in the patients with GHIS, and therefore, this treatment can be considered as an alternative option to IGF‐I injection.
The Resonances of Public Art: Thoughts on the Notion of Co‐Productive Acts and Public Art
Authors: palmer joni m 
Published: March 2018

AbstractUsing a serendipitous public art encounter as a point of departure, this article explores how what I call co‐productive acts are an important part of building relationships between individuals, public art installations, communities, and public art programs. This article is a “thought piece”; as such, I present an introductory examination into an important arena in need of further inquiry: public art and co‐productive acts. As will be made clear, co‐productive acts are different from the production of public art, co‐productions, and collaborations. Though all are important parts of the making of public art, they occur at different times in the life cycle of a piece, and involve different people and interactions. Many people are unaware of their community's public art program (e.g., the process, the funding, and the collection); however, when they experience a piece of public art, there is a possibility that they might have a very different understanding of the piece, themselves, the collection, and the public art program. As a contribution to the literature and practice of public art, I pose questions and suggest directions for further inquiry that might help the field consider how co‐productive acts are, indeed, an important part of the life of public art (installations and municipal public art programs).
No “Blank Canvas”: Public Art and Gentrification in Houston's Third Ward
Authors: WRIGHT WILLIE JAMAAL , HERMAN CAMERON “KHALFANI” 
Published: March 2018

AbstractPublic art and urban renewal have become integral to reconstructing urban landscapes. In this essay we assess how these two spatial practices converge and diverge in the historically and predominately Black community of the Third Ward in Houston, Texas. The essay examines the work of MF Problem and the Black Guys, two Black artist collectives based in the Third Ward. We argue that their public performances critically engage the spatial processes of gentrification and ghettoization in their neighborhood. Furthermore, these performances indicate a unique spatial imaginary held by Black artists that privileges the use value associated with long‐term residents’ views of public and private space over the potential exchange value rooted in urban renewal projects.