bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between structure and in vitro antistaphylococcal effect of plant-derived stilbenes
Authors: Zakova Tereza , Rondevaldova Johana , Bernardos Andrea , Landa Premysl , Kokoska Ladislav 
Published: October 2018

Staphylococcus aureus is a major human pathogen that is responsible for both hospital- and community-acquired infections. Stilbenes are polyphenol compounds of plant origin known to possess a variety of pharmacological properties, such as antibacterial, antiviral, and antifungal effects. This study reports the in vitro growth-inhibitory potential of eight naturally occurring stilbenes against six standard strains and two clinical isolates of S. aureus, using a broth microdilution method, and expressing the results as minimum inhibitory concentrations (MICs). Pterostilbene (MICs = 32–128 μg/ml), piceatannol (MICs = 64–256 μg/ml), and pinostilbene (MICs = 128 μg/ml) are among the active compounds that possess the strongest activity against all microorganisms tested, followed by 3′-hydroxypterostilbene, isorhapontigenin, oxyresveratrol, and rhapontigenin with MICs 128–256 μg/ml. Resveratrol (MIC = 256 μg/ml) exhibited only weak inhibitory effect. Furthermore, structure–activity relationships were studied. Hydroxyl groups at ortho-position (B-3′ and -4′) played crucial roles for the inhibitory effect of hydroxystilbene piceatannol. Compounds with methoxy groups at ring A (3′-hydroxypterostilbene, pinostilbene, and pterostilbene) produced stronger effect against S. aureus than their analogues (isorhapontigenin and rhapontigenin) with methoxy groups at ring B. These findings provide arguments for further investigation of stilbenes as prospective leading structures for development of novel antistaphylococcal agents for topical treatment of skin infections.
Coppinsiella and Seawardiella – two new genera of the xanthorioideae (teloschistaceae, lichen-forming ascomycota)
Authors: Kondratyuk S. Y. , Kärnefelt I. , Lőkös L. , Hur J.-S. , Thell A. 
Published: October 2018

The genera Coppinsiella and Seawardiella are described based on the combined phylogenetic analysis from ITS nrDNA, 28S nrLSU and 12S mtSSU sequences. The affinities of the new genera Orientophila, Athallia, Flavoplaca and Calogaya are discussed. The former Caloplaca lobulata group (or ‘Xanthoria lobulata-Gruppe’ sensu Steiner et Poelt 1982) found to be positioned in the Calogaya clade based on ITS phylogeny while after a three gene phylogeny (based on ITS nrDNA, nrLSU and mtSSU sequences) two species (i.e.: Seawardiella lobulata and described as new S. tasmaniensis) were located in the Seawardiella clade of the Xanthorioideae. Three other species (i.e. Lazarenkoella zoroasteriorum, L. persica and L. polycarpoides) were positioned in the Lazarenkoella-clade of the Brownlielloideae. The position of all species of the Calogaya clade (after ITS phylogeny) should be re-evaluated based on three gene phylogeny from ITS nrDNA, nrLSU and mtSSU sequences. The new species Seawardiella tasmaniensis is described, illustrated and compared with closely related taxa.
New combinations are suggested for eight taxa (i.e. Athallia inconnexa (for Lecanora inconnexa Nyl.), Calogaya safavidiorum (for Caloplaca safavidiorum S. Y. Kondr., in Kondratyuk et al.), Coppinsiella orbicularis stat. et comb. nov. (for Caloplaca substerilis subsp. orbicularis M. Haji Moniri, Vondrák et Malíček), Coppinsiella substerilis (for Caloplaca substerilis Vondrák, Palice et van den Boom, in Vondrák et al.), Coppinsiella ulcerosa (for Caloplaca ulcerosa Coppins et P. James), Lazarenkoella persica (for Xanthoria polycarpoides var. persica J. Steiner); Lazarenkoella polycarpoides (for Xanthoria polycarpoides J. Steiner), and Seawardiella lobulata (for Lecanora lobulata Flörke)).
The impact of heavy and disordered use of games and social media on adolescents’ psychological, social, and school functioning
Authors: van den Eijnden Regina , Koning Ina , Doornwaard Suzan , van Gurp Femke , ter Bogt Tom 
Published: October 2018

AimTo extend the scholarly debate on (a) whether or not the compulsive use of games and social media should be regarded as behavioral addictions (Kardefelt-Winther et al., 2017) and (b) whether the nine DSM-5 criteria for Internet gaming disorder (IGD; American Psychiatric Association [APA], 2013) are appropriate to distinguish highly engaged, non-disordered users of games and social media from disordered users, this study investigated the impact of engaged and disordered use of games and social media on the psychosocial well-being and school performances of adolescents.MethodsAs part of the Digital Youth Project of the University of Utrecht, a three-wave longitudinal sample of 12- to 15-year-old adolescents (N = 538) was utilized. Three annual online measurements were administered in the classroom setting, including IGD, social media disorder, life satisfaction, and perceived social competence. Schools provided information on students’ grade point average.ResultsThe symptoms of disordered use of games and social media showed to have a negative effect on adolescent’s life satisfaction, and the symptoms of disordered gaming showed a negative impact on adolescents’ perceived social competence. On the other hand, heavy use of games and social media predicted positive effects on adolescents’ perceived social competence. However, the heavy use of social media also predicted a decrease in school performances. Several gender differences in these outcomes are discussed.ConclusionThe findings propose that symptoms of disordered use of games and social media predict a decrease in the psychosocial well-being and school performances of adolescents, thereby meeting one of the core criteria of behavioral addictions.
Online dating is associated with sex addiction and social anxiety
Authors: Zlot Yoni , Goldstein Maya , Cohen Koby , Weinstein Aviv 
Published: October 2018

Background and aims
There is an increasing use of the Internet for dating and sexual purpose. The aim of this study was to investigate the contribution of social anxiety and sensation seeking to ratings of sex addiction among those who use dating Internet sites.

Methods
A total of 279 participants (128 males and 151 females), with overall mean age being 25 years (SD = 2.75) and age range of 18–38, answered questionnaires on the Internet. Questionnaires included demographic details, Leibowitz Social Anxiety Scale, Zuckerman Sensation Seeking Scale, and Sexual Addiction Screening Test (SAST).

Results
The users of Internet-dating applications showed higher scores on the SAST than non-users. Second, participants who had low scores of sex addiction had lower social anxiety scores than the participants with high scores of sexual addiction. There was no difference in sensation-seeking scores between participants with low and high scores of sexual addiction.

Discussion and conclusions
The results of this study indicate that social anxiety rather than sensation seeking or gender is a major factor affecting the use of Internet-dating applications for obtaining sexual partners.
Factor structure of the Cybersex Motives Questionnaire
Authors: Franc Elisabeth , Khazaal Yasser , Jasiowka Katarzyna , Lepers Thibault , Bianchi-Demicheli Francesco , Rothen Stéphane 
Published: October 2018

Background and aims
The Internet is widely used for sexual activities and pornography. Little is known, however, about why people look for meetings and sexual interactions through the Internet and about the correlates of cybersex addiction. The goal of this study was to construct a questionnaire for cybersex motives [Cybersex Motives Questionnaire (CysexMQ)] by adapting the Gambling Motives Questionnaire to cybersex use and validating its structure.

Methods
Two online samples of 191 and 204 cybersex users were collected to conduct a principal component analysis (PCA) on the first sample and a confirmatory factor analysis (CFA) on the second. Cronbach’s α and composite reliability were computed to assess internal consistency. Correlations between the CysexMQ and the Sexual Desire Inventory (SDI) were also evaluated.

Results
Two competing models were retained from the PCA, one with two factors and the other with three factors. The CFA showed better fit for the three-factor solution. After three cross-loading items were removed, the results showed that a final 14-item three-factor solution (enhancement, coping, and social motives) was valid (adjusted goodness-of-fit index: 0.993; normed-fit index: 0.978; Tucker–Lewis index: 0.985; comparative fit index: 0.988; root mean square error of approximation: 0.076). Positive correlations were found between the different motives and the subscales of the SDI.

Discussion
The results suggest that the CysexMQ is adequate for the assessment of cybersex motives.
Bidirectional effects of Internet-specific parenting practices and compulsive social media and Internet game use
Authors: Koning Ina M. , Peeters Margot , Finkenauer Catrin , van den Eijnden Regina J. J. M. 
Published: October 2018

IntroductionThis two-wave prospective study investigated the bidirectional relation between Internet-specific parenting (reactive restrictions, Internet-specific rules, and frequency and quality of communication about Internet) and adolescents’ symptoms of social media disorder (SMD) and Internet gaming disorder (IGD). In addition, we investigated whether this relation was different for boys and girls.MethodsA sample of 352 adolescents (48.9% boys,Mage = 13.9,SDage = 0.74, range: 11–15) completed questionnaires at two waves. Zero-inflated cross-lagged analyses in Mplus were performed to predict the level of IGD and SMD symptoms by Internet-specific parenting practices and vice versa, while controlling for age, level of education, and outcome at T1.ResultsMore frequent parent–adolescent communication about Internet predicted more IGD (β = 0.26,p = .03) and SMD symptoms among boys, and more restrictive rules predicted fewer SMD symptoms among girls (β = −0.23,p = .08). More IGD symptoms predicted more reactive rules (β = 0.20,p = .08) among boys and girls and a higher frequency (β = 0.16,p = .02) and lower quality of communication (β = −0.24,p < .001) among boys and girls, respectively.ConclusionsThis study demonstrates bidirectional relations between Internet-specific parenting and IGD symptoms, but not SMD symptoms. Displaying IGD symptoms seems to elicit ineffective parental responses, which may further exacerbate problematic involvement in gaming. With respect to problematic social use media among girls, this study suggests that parents should set strict rules regarding Internet use, prior to problematic use of social media. Longitudinal studies on the role of parenting in development of Internet-related disorders would be promising in enhancing our understanding of how parents can effectively prevent problematic involvement in online behaviors among their children.
Tendencies toward Internet-pornography-use disorder: Differences in men and women regarding attentional biases to pornographic stimuli
Authors: Pekal Jaro , Laier Christian , Snagowski Jan , Stark Rudolf , Brand Matthias 
Published: October 2018

Background and aimsSeveral authors consider Internet-pornography-use disorder (IPD) as addictive disorder. One of the mechanisms that has been intensively studied in substance- and non-substance-use disorders is an enhanced attentional bias toward addiction-related cues. Attentional biases are described as cognitive processes of individual’s perception affected by the addiction-related cues caused by the conditioned incentive salience of the cue itself. It is assumed in the I-PACE model that in individuals prone to develop IPD symptoms implicit cognitions as well as cue-reactivity and craving arise and increase within the addiction process.MethodsTo investigate the role of attentional biases in the development of IPD, we investigated a sample of 174 male and female participants. Attentional bias was measured with the Visual Probe Task, in which participants had to react on arrows appearing after pornographic or neutral pictures. In addition, participants had to indicate their sexual arousal induced by pornographic pictures. Furthermore, tendencies toward IPD were measured using the short-Internetsex Addiction Test.ResultsThe results of this study showed a relationship between attentional bias and symptom severity of IPD partially mediated by indicators for cue-reactivity and craving. While men and women generally differ in reaction times due to pornographic pictures, a moderated regression analysis revealed that attentional biases occur independently of sex in the context of IPD symptoms.DiscussionThe results support theoretical assumptions of the I-PACE model regarding the incentive salience of addiction-related cues and are consistent with studies addressing cue-reactivity and craving in substance-use disorders.
The crucial role of recovery capital in individuals with a gambling disorder
Authors: Gavriel-Fried Belle 
Published: October 2018

Background and aims
The concept of recovery capital (RC) describes the internal and external resources that individuals draw upon to initiate and sustain the processes of addiction recovery. This concept has been primarily applied to individuals recovering from substance addictions. In this study, the RC concept was applied to individuals with a gambling disorder (GD) to test its associations with the diagnosis and severity of GD and with levels of psychopathology as manifested in depression and anxiety.

Methods
A sample of 140 individuals who recovered or did not recover from a GD was drawn from lists of former and currently treated individuals in five gambling treatment centers in Israel. The DSM-5 diagnostic criteria for GD, Assessment of Recovery Capital and Brief Assessment of Recovery Capital Scales adapted to Gambling, Generalized Anxiety Disorder Scale, and the Patient Health Questionnaire 9 which measures depression were used.

Results
RC clearly distinguishes between individuals who have recovered from GD and those who have not. A structural equation model showed significant negative associations between RC and GD severity, depression, and generalized anxiety. The associations between GD severity and depression and anxiety were not significant. However, when omitting the path between RC and depression/anxiety, the associations between GD and depression/anxiety became significant.

Conclusions
RC plays an important role in GD severity and diagnosis, as well as in psychopathology. This study extends the concept of RC to the area of gambling and contributes to the growing body of studies that have found parallels and common denominators between substance addiction and behavioral addictions.
Bidirectional predictions between Internet addiction and probable depression among Chinese adolescents
Authors: Lau Joseph T. F. , Walden Danielle L. , Wu Anise M. S. , Cheng Kit-man , Lau Mason C. M. , Mo Phoenix K. H. 
Published: October 2018

Background and aims
The aim of the study is to investigate (a) whether probable depression status assessed at baseline prospectively predicted new incidence of Internet addiction (IA) at the 12-month follow-up and (b) whether IA status assessed at baseline prospectively predicted new incidence of probable depression at follow-up.

Methods
We conducted a 12-month cohort study (n = 8,286) among Hong Kong secondary students, and derived two subsamples. The first subsample (n = 6,954) included students who were non-IA at baseline, using the Chen Internet Addiction Scale (≤63), and another included non-depressed cases at baseline (n = 3,589), using the Center for Epidemiological Studies Depression Scale (<16).

Results
In the first subsample, 11.5% of the non-IA cases developed IA during follow-up, and probable depression status at baseline significantly predicted new incidence of IA [severe depression: adjusted odds ratio (ORa) = 2.50, 95% CI = 2.07, 3.01; moderate: ORa = 1.82, 95% CI = 1.45, 2.28; mild: ORa = 1.65, 95% CI = 1.32, 2.05; reference: non-depressed], after adjusting for sociodemographic factors. In the second subsample, 38.9% of those non-depressed participants developed probable depression during follow-up. Adjusted analysis showed that baseline IA status also significantly predicted new incidence of probable depression (ORa = 1.57, 95% CI = 1.18, 2.09).

Discussion and conclusions
The high incidence of probable depression is a concern that warrants interventions, as depression has lasting harmful effects in adolescents. Baseline probable depression predicted IA at follow-up and vice versa, among those who were free from IA/probable depression at baseline. Healthcare workers, teachers, and parents need to be made aware of this bidirectional finding. Interventions, both IA and depression prevention, should thus take both problems into consideration.
The use of naltrexone in pathological and problem gambling: A UK case series
Authors: Ward Sophie , Smith Neil , Bowden-Jones Henrietta 
Published: October 2018

Background and aims
To investigate the potential indications and adverse effects of using the opioid antagonist naltrexone to treat problem gamblers.

Case presentation
The files of the 1,192 patients who were referred to the National Problem Gambling Clinic between January 2015 and June 2016 were audited. Seventeen patients were considered appropriate for treatment with naltrexone, having attended and failed to respond to psychological therapies at the clinic. Fourteen patients were placed on a regimen of 50 mg/day naltrexone.

Discussion
Of the 14 patients who were treated with naltrexone, there were 10 for whom sufficient follow-up existed to analyze the treatment efficacy and side effects of naltrexone. Patients showed significant decreases in their craving to gamble and the majority (60%) were able to abstain completely from gambling in the treatment period, with a further 20% reducing their gambling to almost nothing. The reported side effects from the naltrexone included: loss of appetite, gastrointestinal pain, headaches, sedation, dizziness, and vivid dreams. Two patients with concurrent alcohol-use disorder relapsed during the treatment. One patient relapsed after the treatment period.

Conclusions
The study showed significant outcomes in reducing gambling cravings for the sample set. Given the design of the study as a case series, there was no control group, and a number of patients were on other psychotropic medications. We recommend care when prescribing to those suffering from concurrent alcohol-use disorder.
Clustering of treatment-seeking women with gambling disorder
Authors: Granero Roser , Fernández-Aranda Fernando , Mestre-Bach Gemma , Steward Trevor , García-Caro Bárbara , Prever Fulvia , Gavriel-Fried Belle , del Pino-Gutiérrez Amparo , Moragas Laura , Aymamí Neus , Gómez-Peña Mónica , Mena-Moreno Teresa , Martín-Romera Virginia , Menchón José M. , Jiménez-Murcia Susana 
Published: October 2018

Background
The prevalence of gambling disorder (GD) in women has increased, but, to date, few studies have explored the features of clinical GD subtypes in female samples.

Aims
The aim of this study is to identify empirical clusters based on clinical/sociodemographic variables in a sample of treatment-seeking women with GD.

Methods
Agglomerative hierarchical clustering was applied to a sample of n = 280 patients, using sociodemographic variables, psychopathology, and personality traits as indicators for the grouping procedure.

Results
Three mutually exclusive groups were obtained: (a) Cluster 1 (highly dysfunctional; n = 82, 29.3%) endorsed the highest levels in gambling severity, comorbid psychopathology, novelty seeking, harm avoidance, and self-transcendence, and the lowest scores in self-directedness and cooperativeness; (b) Cluster 2 (dysfunctional; n = 142, 50.7%) achieved medium mean scores in gambling severity and psychopathological symptoms; and (c) Cluster 3 (functional; n = 56, 20.0%) obtained the lowest mean scores in gambling severity and in psychopathology, and a personality profile characterized by low levels in novelty seeking, harm avoidance, and self-transcendence, and the highest levels in self-directedness and cooperativeness.

Discussion and conclusions
This study sheds light on the clinical heterogeneity of women suffering from GD. Identifying the differing features of women with GD is vital to developing prevention programs and personalized treatment protocols for this overlooked population.
Adaptation and validation of Richmond Compulsive Buying Scale in Chinese population
Authors: Lam Simon Ching , Chan Zoe Sze-Long , Chong Andy Chun-Yin , Wong Wendy Wing-Chi , Ye Jiawen 
Published: October 2018

Background and aims
Compulsive buying (CB) is a behavioral addiction that is conceptualized as an obsessive–compulsive and impulsive–control disorder. The Richmond Compulsive Buying Scale (RCBS), a six-item self-reporting instrument that has been validated worldwide, was developed based on this theoretical background. This study aimed to adapt RCBS to the Chinese population (RCBS-TC) to guide future national and international prevalence studies.

Methods
This methodological study was conducted in two phases. Phase 1 involved the forward and backward translation of RCBS, the content and face validation of the RCBS, and the evaluation of its translation adequacy. Phase 2 involved the psychometric testing of RCBS-TC for its internal consistency, stability, and construct validity using confirmatory factor analysis (CFA).

Results
In Phase 1, RCBS-TC obtained satisfactory item-level (I-CVI = 83.3%–100%) and scale-level content validity index (CVI/AVE = 97.2%), comprehensibility (100%), and translation adequacy [intraclass correlation coefficient (ICC) = 0.858]. In Phase 2, based on data collected from 821 adults, RCBS-TC demonstrated a satisfactory internal consistency (Cronbach’s α = .88; corrected item-total correlation coefficients = 0.61–0.78) 2-week test–retest reliability (ICC = 0.82 based on 61 university students). For construct validation, the CFA results indicated that the corrected first-order two-factor models were acceptable with the same goodness-of-fit indices (χ2/df = 8.56, CFI = 0.99, NFI = 0.98, IFI = 0.99, and RMSEA = 0.09). The 2-week test–retest reliability of RCBS-TC (n = 61) was also satisfactory (ICC = 0.82).

Discussion and conclusions
This methodological study adopted appropriate and stringent procedures to ensure that the translation and validation of RCBS-TC was of quality. The results indicate that this scale has a satisfactory reliability and validity for the Chinese population.