bluuebunny/crossref_metadata_2025_split huggingface dataset:
First Precambrian palaeomagnetic data from the Mawson Craton (East Antarctica) and tectonic implications
Authors: Liu Yebo , Li Zheng-Xiang , Pisarevsky Sergei A. , Kirscher Uwe , Mitchell Ross N. , Stark J. Camilla , Clark Chris , Hand Martin 
Published: October 2018

AbstractA pilot palaeomagnetic study was conducted on the recently dated with in situ SHRIMP U-Pb method at 1134 ± 9 Ma (U-Pb, zircon and baddeleyite) Bunger Hills dykes of the Mawson Craton (East Antarctica). Of the six dykes sampled, three revealed meaningful results providing the first well-dated Mesoproterozoic palaeopole at 40.5°S, 150.1°E (A95 = 20°) for the Mawson Craton. Discordance between this new pole and two roughly coeval poles from Dronning Maud Land and Coats Land (East Antarctica) demonstrates that these two terranes were not rigidly connected to the Mawson Craton ca. 1134 Ma. Comparison between the new pole and that of the broadly coeval Lakeview dolerite from the North Australian Craton supports the putative ~40° late Neoproterozoic relative rotation between the North Australian Craton and the combined South and West Australian cratons. A mean ca. 1134 Ma pole for the Proto-Australia Craton is calculated by combining our new pole and that of the Lakeview dolerite after restoring the 40° intracontinental rotation. A comparison of this mean pole with the roughly coeval Abitibi dykes pole from Laurentia confirms that the SWEAT reconstruction of Australia and Laurentia was not viable for ca. 1134 Ma.
Ultrafast soliton and stretched-pulse switchable mode-locked fiber laser with hybrid structure of multimode fiber based saturable absorber
Authors: Zhao Fengyan , Wang Yishan , Wang Hushan , Yan Zhijun , Hu Xiaohong , Zhang Wei , Zhang Ting , Zhou Kaiming 
Published: October 2018

AbstractWe demonstrate an all-fiber mode locked laser based on hybrid structure of multimode fiber saturable absorber (SA) that can realize both conventional soliton and stretched-pulse states. Stable 16.44 MHz conventional soliton pulses are achieved by injecting 80 mW threshold pump power. By increasing the incident pump power to 420 mW, the laser evolves from soliton operation into stretched-pulse mode locking state. 310 fs stretched-pulse are obtained with the same repetition rate as the soliton pulses. The center wavelength and its 3 dB spectrum bandwidth are 1603 nm and 14.2 nm, respectively. For the first time, we experimentally confirm transition between conventional soliton and stretched-pulse in 1.5 μm mode-locked fiber laser by introducing multimode optical fiber SA. Moreover, the maximum single pulse energy of nearly 1 nJ is achieved. Such all-fiber mode-locked lasers based on hybrid structure of multimode fiber are attractive for practical applications without damage and the limitation of life time.
The arrangement of lateral veins along the midvein of leaves is not related to leaf phyllotaxis
Authors: Koyama Kohei , Masuda Teruhisa 
Published: October 2018

AbstractPositions of leaves along a stem usually adhere to a genetically determined, species-specific pattern known as a leaf phyllotaxis. We investigated whether the arrangement of lateral secondary veins along primary midveins adhered to a species-specific pattern that resembled an alternate or opposite phyllotaxis. We analyzed the venation of temperate dicotyledonous species from different taxonomic groups and chose 18 woody and 12 herbaceous species that have reticulated leaf venation. The arrangement of the lateral veins was neither alternate nor opposite for any of the species. Lateral vein arrangements were instead mixtures of symmetric and asymmetric patterns. Our results show that lateral vein arrangements are related neither to stem-level leaf phyllotaxis (alternate vs. opposite) nor to life form (woody vs. herbaceous). Our results are therefore generally consistent with the canalization hypothesis that the locations of lateral veins are not completely specified genetically prior to leaf formation.
Applicability of Dynamic Energy Budget (DEB) models across steep environmental gradients
Authors: Monaco Cristián J. , McQuaid Christopher D. 
Published: October 2018

AbstractRobust ecological forecasting requires accurate predictions of physiological responses to environmental drivers. Energy budget models facilitate this by mechanistically linking biology to abiotic drivers, but are usually ground-truthed under relatively stable physical conditions, omitting temporal/spatial environmental variability. Dynamic Energy Budget (DEB) theory is a powerful framework capable of linking individual fitness to environmental drivers and we tested its ability to accommodate variability by examining model predictions across the rocky shore, a steep ecotone characterized by wide fluctuations in temperature and food availability. We parameterized DEB models for co-existing mid/high-shore (Mytilus galloprovincialis) and mid/low-shore (Perna perna) mussels on the south coast of South Africa. First, we assumed permanently submerged conditions, and then incorporated metabolic depression under low tide conditions, using detailed data of tidal cycles, body temperature and variability in food over 12 months at three sites. Models provided good estimates of shell length for both species across the shore, but predictions of gonadosomatic index were consistently lower than observed. Model disagreement could reflect the effects of details of biology and/or difficulties in capturing environmental variability, emphasising the need to incorporate both. Our approach provides guidelines for incorporating environmental variability and long-term change into mechanistic models to improve ecological predictions.
DArTseq-based analysis of genomic relationships among species of tribe Triticeae
Authors: Edet Offiong U. , Gorafi Yasir S. A. , Nasuda Shuhei , Tsujimoto Hisashi 
Published: October 2018

AbstractPrecise utilization of wild genetic resources to improve the resistance of their cultivated relatives to environmental growth limiting factors, such as salinity stress and diseases, requires a clear understanding of their genomic relationships. Although seriously criticized, analyzing these relationships in tribe Triticeae has largely been based on meiotic chromosome pairing in hybrids of wide crosses, a specialized and labourious strategy. In this study, DArTseq, an efficient genotyping-by-sequencing platform, was applied to analyze the genomes of 34 Triticeae species. We reconstructed the phylogenetic relationships among diploid and polyploid Aegilops and Triticum species, including hexaploid wheat. Tentatively, we have identified the diploid genomes that are likely to have been involved in the evolution of five polyploid species of Aegilops, which have remained unresolved for decades. Explanations which cast light on the progenitor of the A genomes and the complex genomic status of the B/G genomes of polyploid Triticum species in the Emmer and Timopheevi lineages of wheat have also been provided. This study has, therefore, demonstrated that DArTseq genotyping can be effectively applied to analyze the genomes of plants, especially where their genome sequence information are not available.
A quantile regression approach to explain the relationship of Fatigue and Cortisol, Cytokine among Koreans with Hepatitis B
Authors: Jang Yeonsoo , Kim Jeong Hyun , Lee Hyangkyu , Lee Kyunghwa , Ahn Sang Hoon 
Published: October 2018

AbstractFatigue is a major symptom among patients with Hepatitis B virus (HBV). However, the physiological mechanisms regarding mediate fatigue and the relationships between fatigue, cortisol and cytokines are unclear in patients with HBV. The purpose of this study was to examine the relationships between perceived fatigue, cortisol, and cytokines in Korean patients with HBV. The mean score for overall fatigue was moderate. In linear regression analyses, TNF-α was only significant as a predictor of fatigue. In quantile regression analyses, the cortisol level was significant in the 70th, 80th, 90th quantiles in the cognitive/mood fatigue subdimension, which correspond to severe levels of fatigue. IL-6 levels were significant in 90th quantile in overall fatigue and in the cognitive/mood fatigue subdimension. Cortisol, IL-6, and TNF- α were related to perceived fatigue in patients with HBV, particularly in the cognitive/mood dimension. This suggests that the fatigue patterns of patients with HBV are related to their mental and mood states and physical responses, such as cortisol and cytokine levels, are correlated with the nature of the fatigue. In the clinic, interventions to manage fatigue in patients with HBV should be developed based on the characteristics of the fatigue.
Dissection of differential vanadate sensitivity in two Ogataea species links protein glycosylation and phosphate transport regulation
Authors: Karginov Azamat V. , Fokina Anastasia V. , Kang Hyun Ah , Kalebina Tatyana S. , Sabirzyanova Tatyana A. , Ter-Avanesyan Michael D. , Agaphonov Michael O. 
Published: October 2018

AbstractThe closely related yeastsOgataea polymorphaandO.parapolymorphadiffer drastically from each other by sensitivity to the toxic phosphate analog vanadate. Search for genes underlying this difference revealed two genes, one designated asABV1(AlcianBlue staining,Vanadate resistance), which encodes a homologue ofSaccharomyces cerevisiaeMnn4 responsible for attachment of mannosylphosphate to glycoside chains of secretory proteins, and the other designated as itsS.cerevisiaehomologuePHO87, encoding the plasma membrane low affinity phosphate sensor/transporter. The effect of Pho87 on vanadate resistance was bidirectional, since it decreased the resistance on phosphate-depleted medium, but was required for pronounced protection against vanadate by external phosphate. This highlights the dual function of this protein as a low affinity phosphate transporter and an external phosphate sensor. Involvement of Pho87 in phosphate sensing was confirmed by its effects on regulation of the promoter of thePHO84gene, encoding a high affinity phosphate transporter. The effect of Abv1 was also complex, since it influenced Pho87 level and enhanced repression of thePHO84promoterviaa Pho87-independent pathway. Role of the identified genes in the difference in vanadate resistance betweenO.polymorphaandO.parapolymorphais discussed.
Long-lived non-classical correlations towards quantum communication at room temperature
Authors: Zugenmaier Michael , Dideriksen Karsten B. , Sørensen Anders S. , Albrecht Boris , Polzik Eugene S. 
Published: October 2018

AbstractHeralded single-photon sources with on-demand readout are a key enabling technology for distributed photonic networks. Such sources have been demonstrated in both cryogenic solid-state and cold-atoms systems. Practical long-distance quantum communication may benefit from using technologically simple systems such as room-temperature atomic vapours. However, atomic motion has so far limited the single-excitation lifetime in such systems to the microsecond range. Here we demonstrate efficient heralding and readout of single collective excitations created in warm caesium vapour. Using the principle of motional averaging we achieve a collective excitation lifetime of 0.27 ± 0.04 ms, two orders of magnitude larger than previously achieved for single excitations in room-temperature sources. We experimentally verify non-classicality of the light-matter correlations by observing a violation of the Cauchy-Schwarz inequality with R = 1.4 ± 0.1 > 1. Through spectral and temporal analysis we investigate the readout noise that limits single-photon operation of the source.
Association of ADAMTS4 and ADAMTS5 polymorphisms with musculoskeletal degenerative diseases: a systematic review and meta-analysis
Authors: Huo Jian-Zhong , Ji Xing-Hua , Su Zhong-Yi , Shang Peng , Gao Fei 
Published: October 2018

Objective: This meta-analysis and systematic review was performed with the aim of investigating the association between a disintegrin and metalloproteinase with thrombospondin motif (ADAMTS)4, AMDMTS5 polymorphisms and risk of musculoskeletal degenerative diseases.
Methods: PubMed, EMBASE, ISI Web of Science, Wanfang and CNKI were searched from their inception until May 2018 to identify eligible studies. Data from individual studies were extracted using a standardized data collection sheet. The estimate of association between ADAMTS4, AMDMTS5 polymorphisms and risk of musculoskeletal degenerative diseases was expressed as odds ratio (OR) along with its related 95% confidence interval (95%CI) under an allelic model of inheritance. Meta-analysis was conducted using RevMan 5.3 software. Subgroup-analyses by ethnicity and type of diseases were performed.
Results: Eight studies including ten cohorts were included in this meta-analysis. The meta-analyses results based on seven studies showed that rs226794 in ADAMTS5 gene was not associated with risk of musculoskeletal degenerative diseases (A vs. G: OR 1.07; 95%CI 0.97–1.19; P=0.16). Rs2830585 in ADAMTS5 was significantly associated with musculoskeletal degenerative diseases in only Asians (OR 1.41, 95%CI 1.18–1.68; P=0.0001), but not in Caucasians. Since only two of the collected studies referred to ADAMTS4, we did not perform meta-analysis for these comparisons.
Conclusion: Taken together, rs226794 and rs2830585 in ADAMTS5 gene were not associated with musculoskeletal degenerative diseases in overall population, but there seemed to be an ethnicity-dependent effect of rs2830585 in the risk of musculoskeletal degenerative diseases. Insufficient evidence was found to support the association of other single nucleotide polymorphisms and musculoskeletal degenerative diseases.
ALMA detects a radial disk wind in DG Tauri
Authors: Güdel M. , Eibensteiner C. , Dionatos O. , Audard M. , Forbrich J. , Kraus S. , Rab Ch. , Schneider Ch. , Skinner S. , Vorobyov E. 
Published: October 2018

Aims. We aim to use the high spatial resolution of the Atacama Large Millimeter/submillimeter Array (ALMA) to map the flow pattern of molecular gas near DG Tauri and its disk, a young stellar object driving a jet and a molecular outflow.
Methods. We use observations from ALMA in the J = 2 − 1 transition of 12CO, 13CO, and C18O to study the Keplerian disk of DG Tauri and outflows that may be related to the disk and the jet.
Results. We find a new wind component flowing radially at a steep angle (≈25° from the vertical) above the disk with a velocity of ≈3.1 km s−1. It continues the trend of decreasing velocity for increasing distance from the jet axis (“onion-like velocity structure”).
Conclusions. The new component is located close to the protostellar disk surface and may be related to photoevaporative winds.
Therapieanpassungen mithilfe von Trendpfeilen bei kontinuierlichen Glukosemonitoring (CGM)-Systemen
Authors: Ziegler Ralph , Siegmund Thorsten , von Sengbusch Simone , Kroeger Jens , Schubert Oliver , Werkmeister Petra , Deiss Dorothee 
Published: October 2018

ZusammenfassungDie unterschiedlichen Systeme zum kontinuierlichen interstitiellen Glukosemonitoring nutzen Trendpfeile, mit denen dem Anwender in grafischer Form eine Prognose zum künftigen Glukoseverlauf angezeigt wird. Sie werden sowohl beim Glukosemonitoring mit „Real-Time“-Alarmen als auch beim Glukosemonitoring mit intermittierendem Scannen genutzt. Die Trendpfeile sind für viele Menschen mit Diabetes eine wichtige Grundlage für Stoffwechselkorrekturen, weshalb ihre Interpretation zur Voraussetzung für adäquate Therapieentscheidungen wird. Ziel dieser Publikation ist es, auf der Grundlage verfügbarer Vorschläge zur Trendpfeilinterpretation eine allgemein gültige Handlungsanweisung für Diabetesteams und Nutzer von kontinuierlichem Glukosemonitoring mit der Möglichkeit der notwendigen individuellen Anpassung zu geben.
Internistische Onkologie
Authors: Zschäbitz Stefanie , Jäger Dirk 
Published: October 2018

ZusammenfassungAuf dem diesjährigen ASCO wurden einige Studien präsentiert, die zu Leitlinienänderungen führen werden. Erfreulicherweise können durch positive
Nicht-Unterlegenheitsstudien die Behandlungsstrategien für manche unserer Patienten zukünftig schonender ausfallen. Wir möchten im Folgenden für die
wesentlichen Tumorentitäten die klinisch relevanten Präsentationen zusammenfassen.
Psychische Belastung bei unbegleiteten jungen Geflüchteten in Jugendhilfeeinrichtungen
Authors: Sierau Susan , Schneider Esther , Nesterko Yuriy , von Klitzing Kai , Glaesmer Heide 
Published: October 2018

Zusammenfassung
Ziel der Studie Häufigkeiten psychischer Auffälligkeiten bei unbegleiteten Geflüchteten erfassen.
Methodik Soziodemografie und psychische Belastung wurden in der Selbst- und Fremdbeurteilung an 105 Jugendlichen erhoben.
Ergebnisse Am häufigsten waren Auffälligkeiten in den Bereichen Depression (42 %), Verhalten (35 %) und posttraumatische Belastungsstörung (32 %). Die Jugendlichen berichteten mehr Probleme mit Gleichaltrigen, die Betreuer mehr Probleme der Jugendlichen in den Bereichen Emotion, Verhalten und Hyperaktivität.
Schlussfolgerung Die Daten verdeutlichen den psychologischen Hilfebedarf dieser Gruppe.
Identifying Effective Behavior Change Techniques for Alcohol and Illicit Substance Use During Pregnancy: A Systematic Review
Authors: Fergie Libby , Campbell Katarzyna A , Coleman-Haynes Tom , Ussher Michael , Cooper Sue , Coleman Tim 
Published: October 2018

Abstract

Background
During pregnancy, consuming alcohol and using illicit drugs can have serious health implications for both mother and child. Behavioral change interventions, especially those underpinned by theoretical constructs, can be effective in reducing harmful substance use among pregnant women.

Purpose
To understand what type of behavior change mechanisms could be useful in reducing alcohol consumption or achieving abstinence from illicit drug use during pregnancy, this review aimed to identify behavior change techniques (BCTs), the smallest, active components of interventions that may be effective. It also aimed to establish the extent that psychosocial-based theories were used to inform intervention design.

Methods
To identify eligible randomized controlled trials (RCTs), five databases were searched electronically from the end search dates of the most recent Cochrane systematic reviews on behavioral interventions for each behavior, until March 2018. Within the RCTs, intervention descriptions were analyzed for BCT content and extent of theory use in the intervention design process and outcome measurements, in each trial, was established. “Effectiveness percentages,” the number of times a BCT had been a component of an effective intervention divided by the total number of interventions it had been used in, were calculated for BCTs used in two or more trials.

Results
Including all RCTs from the Cochrane reviews, and those published subsequently, nine alcohol and six illicit drug trials were identified. Interventions tested in four alcohol RCTs and no illicit drugs RCTs showed positive results. Subsequent data were extracted for alcohol consumption trials only. Thirteen BCTs showed “potential effectiveness” for alcohol consumption. Six of nine included alcohol trials reported using theory but not extensively.

Conclusions
Action planning, behavioral contract, prompts/cues, self-talk, offer/direct toward written material, problem solving, feedback on behavior, social support (unspecified), information about health consequences, behavior substitution, assess current readiness and ability to reduce excess alcohol consumption, goal setting (behavior), and tailor interactions appropriately are BCTs that could be useful in helping reduce alcohol consumption among pregnant women.
Understanding the Evolution of Antibiotic-nonsusceptible Pneumococcal Nasopharyngeal Colonization Following Pneumococcal Conjugate Vaccine Implementation in Young Children
Authors: Danino Dana , Givon-Lavi Noga , Ben-Shimol Shalom , Greenberg David , Dagan Ron 
Published: October 2018

Abstract

Background
Four main processes determine pneumococcal conjugate vaccine (PCV) antibiotic-nonsusceptible Streptococcus pneumoniae (ANSP) carriage: reduction of PCV serotypes, increase of non-PCV serotypes, potential overall reduction in carriage, and within-serotype nonsusceptibility resulting from continuous antibiotic pressure. The post-PCV implementation dynamics of these components were examined in young children from 2 distinct ethnic populations: Jewish and Bedouin.

Methods
We performed ongoing, prospective, population-based, active surveillance initiated at the time of 7- and 13-valent PCVs (PCV7; PCV13) implementation. Nasopharyngeal cultures for S. pneumoniae were obtained daily from children aged <5 years who visited the only pediatric emergency room in the district during a 6-year period (2009 to 2015).

Results
Of 8446 nasopharyngeal samples, 48.3% were positive (42.0% and 52.8% for Jewish and Bedouin children, respectively; P < .001). Nonsusceptibility was significantly more frequent among PCV serotypes than among non-PCV serotypes and among Bedouin children than among Jewish children. PCV serotype carriage declined by 80%, while that of non-PCV serotypes increased by 140%. The overall (all serotypes) pneumococcal carriage significantly declined (33% and 11% in Bedouin and Jewish children, respectively). Among non-PCV isolates, the proportion of ANSP significantly increased with time in both populations. As a summation of all 4 processes, ANSP carriage significantly decreased among both Bedouin and Jewish children.

Conclusions
PCV impact on ANSP nasopharyngeal carriage is a dynamic, multicomponent process, highly dependent on antibiotic consumption in the community, which may result in a continuous increase in antibiotic resistance in the replacing serotypes.
Optimizing state change detection in functional temporal networks through dynamic community detection
Authors: Vaiana Michael , Goldberg Ethan M , Muldoon Sarah F 
Published: October 2018

Abstract
Dynamic community detection provides a coherent description of network clusters over time, allowing one to track the growth and death of communities as the network evolves. However, modularity maximization, a popular method for performing multilayer community detection, requires the specification of an appropriate null network as well as resolution and interlayer coupling parameters. Importantly, the ability of the algorithm to accurately detect community evolution is dependent on the choice of these parameters. In functional temporal networks, where evolving communities reflect changing functional relationships between network nodes, it is especially important that the detected communities reflect any state changes of the system. Here, we present analytical work suggesting that a uniform null network provides improved sensitivity to the detection of small evolving communities in temporal networks with positive edge weights bounded above by 1, such as certain types of correlation networks. We then propose a method for increasing the sensitivity of modularity maximization to state changes in nodal dynamics by modelling self-identity links between layers based on the self-similarity of the network nodes between layers. This method is more appropriate for functional temporal networks from both a modelling and mathematical perspective, as it incorporates the dynamic nature of network nodes. We motivate our method based on applications in neuroscience where network nodes represent neurons and functional edges represent similarity of firing patterns in time. We show that in simulated data sets of neuronal spike trains, updating interlayer links based on the firing properties of the neurons provides superior community detection of evolving network structure when groups of neurons change their firing properties over time. Finally, we apply our method to experimental calcium imaging data that monitors the spiking activity of hundreds of neurons to track the evolution of neuronal communities during a state change from the awake to anaesthetized state.