bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pelvic Organ Prolapse Repair with Mesh: Mid-Term Efficacy and Complications
Authors: Mateu Arrom Laura , Errando Smet Carlos , Gutierrez Ruiz Cristina , Araño Pedro , Palou Redorta Joan 
Published: June 2018

<b><i>Introduction:</i></b> Our aim was to assess the efficacy and complications of pelvic organ prolapse (POP) correction with transvaginal mesh (TVM). <b><i>Materials and Methods:</i></b> We retrospectively assessed patients who had undergone a repair of an apical (primary or recurrent) or recurrent POP using TVM in our department since 2007. Meshes used were Prolift®, Elevate®, and Surelift®. Satisfaction with surgery was assessed on a 0–10 scale. <b><i>Results:</i></b> A total of 83 patients were included (33 Prolift®, 36 Elevate®, 14 Surelift®), with a mean age of 67.8 ± 9.7 years. Eighteen (21.6%) patients underwent a recurrent POP correction. Follow-up was 49 ± 34 months. Twelve (14.4%) symptomatic recurrences were identified, 3 of which required further surgery. Satisfaction was 8.7. Four (4.8%) vaginal exposures were detected, 2 of which required partial mesh removal. Three (3.6%) cases of dyspareunia and 1 (1.2%) case of mild pelvic pain were reported, which did not require further treatment. <b><i>Conclusion:</i></b> The use of TVM for apical or recurrent POP repair is effective and is associated with a high satisfaction rate while complications are infrequent.
Comparação entre sistemas para criação de acervos digitais: análise dos softwares livres DSpace, EPrints, Fedora, Greenstone e Islandora a partir de novas dimensões analíticas
Authors: Martins Dalton Lopes , Silva Marcel Ferrante , Siqueira Joyce 
Published: June 2018

Os repositórios digitais estão cada vez mais integrados ao cotidiano, principalmente por possibilitar a universalização do conhecimento por meio de acesso rápido e, muitas vezes, gratuito a documentos de toda ordem. Existem atualmente diversas opções de softwares disponíveis para este fim, dessa forma, para auxiliar os gestores responsáveis por definir a melhor ferramenta para seu projeto, originou-se o objetivo desta pesquisa, de analisar cinco principais softwares livres: DSpace, EPrints, Fedora, Greenstone e Islandora e verificar quais destes atendem o maior número de requisitos previamente classificados em dimensões analíticas. Assim, foram analisadas 182 funcionalidades, divididas em 10 dimensões analíticas, dos quais obteve-se que o DSpace atende uma maior porcentagem de funcionalidades, com 57%, sendo seguido pelo EPrints, com 38%, a Islandora, com 36%, o Greenstone, com 23% e o Fedora, com 19%. A partir deste resultado, pretende-se oferecer aos gestores importante ferramenta de decisão.
Two new deep-water species of the genus Thorogobius (Teleostei: Gobiidae) from the upper continental slope of the Eastern Central Atlantic
Authors: SAUBERER MICHAEL , IWAMOTO TOMIO , AHNELT HARALD 
Published: June 2018

Two new gobiid species, Thorogobius alvheimi sp. nov. and Thorogobius laureatus sp. nov. (Teleostei: Gobiiformes: Gobiidae), are described from the outer continental shelf and upper slope of the Eastern Central Atlantic off Angola, Ghana and São Tomé and Príncipe. The specimens were trawled from depths between 57 and 208 m. The new species are most similar to Thorogobius angolensis. Thorogobius alvheimi sp. nov. is distinguished from its congeners in the combination of following characters. Fins: first dorsal fin with the second and third spines distinctly elongated; pectoral fin ray count 20–21; pelvic disc complete and short with well-developed anterior membrane (frenum) and pointed lateral lobes. Scales: nape and predorsal area naked; no scales on opercle; scales in longitudinal series 27–31. Pattern of free neuromasts: supratemporal rows tr and trp developed, extending transversally between pores H and K; longitudinal row g short, not passing row m posteriorly and distinctly distant from row h; infraorbital row 6 long, ventrally extending to lower margin of preopercle, its ventral section 6i originating anterior to its dorsal section 6s; posterior lateral row h reaching anteriorly above posterior third of opercle. Coloration: body uniformly pale fawn and brown; margin of scale pockets dark brown pigmented, yielding a reticulated pattern; pale spots on nape and predorsal area; caudal fin uniformly dusky greyish. Thorogobius laureatus sp. nov. is distinguished from its congeners in the combination of following characters. Fins: first dorsal fin the second and third spines distinctly elongated; pectoral fin ray count 19–22; pelvic disc complete, short, with well-developed anterior membrane (frenum) with pointed lateral lobes. Scales: scales on sides of predorsal area and midline mostly naked; no scales on opercle; scales in longitudinal series 24–27. Pattern of free neuromasts (sensory papillae): supratemporal rows tr and trp developed, extending transversally between pores H and K; longitudinal row g long, passing row m posteriorly and relatively close to row h; infraorbital row 6 long, ventrally extending to lower margin of preopercle, its ventral (6i) and dorsal (6s) originating opposite to each other; posterior lateral rows: row h long, reaching anteriorly above middle of opercle. Coloration: body pale fawn and brownish; margin of scale pockets dark brown pigmented, yielding a reticulated pattern; five brown blotches on flanks in lateral midline from below first dorsal fin to caudal peduncle; caudal fin with six or seven distinct dark vertical bands.
Impact of a university physical conditioning sport education season on students’ fitness levels
Authors: Wahl-Alexander Zachary , Chomentowski Peter 
Published: June 2018

Objectives: Basic activity programmes are offered in numerous universities, with the primary objective of increasing involvement in different physical activities while instilling the value of lifetime fitness. Although these programmes have been shown to be beneficial, there is a lack of research focused on their effectiveness of improving physical activity levels. Therefore, the purpose of this study was to determine changes in college-aged students’ aerobic fitness levels following participation in a university physical conditioning course. Methods: Participants in this study were 47 university students from two physical conditioning courses, one taught using Sport Education and another taught with direct instruction. Student’s aerobic fitness levels were assessed through the Progressive Aerobic Cardiovascular Endurance Run (PACER) and the one-mile run prior to and following the 5-month course. Results: Results indicated a significant difference between groups on the total number of laps completed during the PACER test. Conclusion: The findings of this study demonstrate that students who participated in the Sport Education physical conditioning course experienced significant improvements over time for both tests and a significant improvement over traditional instruction in the number of PACER laps run.
Access to information in Benin: a case study
Authors: Mabillard Vincent , Kakpovi Bellarminus G. , Cottier Bertil 
Published: June 2018

Transparency is nowadays at the top of the agenda for most governments. The number of countries that have adopted a law on access to administrative documents is on the rise. Access to information laws do not provide a substitute for transparency, but they may signal the willingness of a government to increase openness. So far, most studies have focused on states where such laws exist, especially in Europe and North America, while very little research has been conducted in Africa. This contribution is intended to capitalise on previous research to present the case of Benin. Research questions focus on the development of access to information, barriers to an introduction of a stronger law in that country and the administration’s expectations regarding transparency. Data are based on interviews with civil society organisations, an official in charge of access to administrative documents in Benin and several employees of the national administration. Findings show how contextual and institutional differences shape transparency reforms, the importance of the issue of global awareness and access, and how current practices influence the approach towards access to administrative documents in Benin. Points for practitioners The case of Benin shows how openness can be fostered by the media, members of the parliament and civil society organisations. The combined action of these diverse stakeholders, also supported by regional and international partners, can lead to increased administrative transparency. This article highlights the commitment of public sector employees to create a more open administration, although they are still facing central implementation issues, such as undertrained staff, lack of resources or the dissemination and understanding of information among the population.
Disseminated Nocardia infection in a female patient with idiopathic thrombocytopenic purpura and long-term glucocorticoid use
Authors: Li Shu , Ma Qingbian , Li Shuo , Zheng Yaan , Chen Yujiao , Xie Rui , Ma Jingwei 
Published: June 2018

Introduction: Nocardiosis is a rare kind of opportunistic infections. Because of its insidious onset and atypical clinical manifestations, diagnosis and early treatment are often delayed. Case presentation: Here we present a 60-year-old Chinese female patient with systemic Nocardia infection, who had been diagnosed with idiopathic thrombocytopenic purpura previously and was misdiagnosed for up to 6 months prior to presenting at our hospital and ultimately achieved clinical cure. Discussion: The patient took prednisone because of ITP for several years which led to immunosuppression. Nocardia infection began from the skin rupture and then spread all over the body with multiple system involvement. The pus culture eventually found Nocardia. Sulphonamides have been the standard treatment for decades and there are several other options. Patients with severe Nocardia infection or immunosuppression are suggested a combined therapy. Conclusion: Nocardiosis is an infection that often resulted in delayed diagnosis because of lack of specificity of the clinical profile and the difficulty in culturing the bacteria. It should be included in the differential diagnosis of patients in which there are cutaneous, respiratory or neurological manifestations, especially in immunosuppressed individuals.
Improving ambulatory blood pressure monitoring knowledge in nurses and doctors: impact of a training intervention
Authors: Dalfó-Pibernat Artur , Dalfó Baqué Antoni , Pelegrina Rodríguez Francisco Javier , Garin Olatz , Duran Xavier , Cladellas Capdevila Mercè , Comin Colet Josep 
Published: June 2018

Introduction: Ambulatory blood pressure monitoring (ABPM) is fundamental to diagnosing and monitoring arterial hypertension (HTN), yet it is not known how effective training could be in improving knowledge of ABPM. Purpose: The purpose of this study was to evaluate ABPM knowledge before and after a training activity. Methodology: A before-and-after intervention study of 116 professionals. Data was collected on age, sex, occupational category, work setting, and work experience. ABPM knowledge was determined by a questionnaire to evaluate expertise in understanding and interpreting ABPM results. Results: Multivariate regression analysis showed that, pre-intervention, having more than 20 years’ experience (odds ratio (OR): 5.9; 95% confidence interval (CI): 1.3–33.9; p = 0.049) and being a doctor (OR: 5.7; 95% CI: 1.8–18.3; p = 0.004) were associated with greater ABPM knowledge. Training increased the number of professionals with adequate ABPM knowledge: 85.3% after training vs 26.7% before training. Training increased the questionnaire mean (SD) score by almost 3 (1.7) points: 9 (2.2) after training vs 6.3 (2.2) before training ( p < 0.05). Of the 116 professionals, 90.5% achieved a higher overall score after training. The impact of the intervention was greatest on women nurses older than 45 years and with more years of experience, employed in primary care, and with prior experience of ABPM. Conclusions: Knowledge of ABPM is deficient but can be easily improved by training that is most effective in primary care and among nurses.
Determinants of participation and risk factor control according to attendance in cardiac rehabilitation programmes in coronary patients in Europe: EUROASPIRE IV survey
Authors: Kotseva Kornelia , Wood David , De Bacquer Dirk 
Published: June 2018

AimThe purpose of this study was to describe the proportions of patients referred to and attending cardiac rehabilitation programmes in Europe and to compare lifestyle and risk factor targets achieved according to participation in a cardiac rehabilitation programme.MethodsThe EUROASPIRE IV cross-sectional survey was undertaken in 78 centres from 24 European countries. Consecutive patients aged <80 years with acute coronary syndromes and/or revascularization procedures were interviewed at least six months after their event.ResultsA total of 7998 patients (24% females) were interviewed. Overall, 51% were advised to participate in a cardiac rehabilitation programme and 81% of them attended at least half of the sessions; being 41% of the study population. Older patients, women, those at low socio-economic status or enrolled with percutaneous coronary intervention and unstable angina, as well as those with a previous history of coronary disease, heart failure, hypertension or dysglycaemia were less likely to be advised to follow a cardiac rehabilitation programme. People smoking prior to the recruiting event were less likely to participate. The proportions of patients achieving lifestyle targets were higher in the cardiac rehabilitation programme group as compared to the non-cardiac rehabilitation programme group: stopping smoking (57% vs 47%, p < 0.0001), recommended physical activity levels (47% vs 38%, p < 0.0001) and body mass index<30 kg/m2(65% vs 61%, p=0.0007). However, there were no differences in the blood pressure, lipids and glucose control. Patients who attended a cardiac rehabilitation programme had significantly lower anxiety and depression scores and better medication adherence.ConclusionsOnly half of all coronary patients were referred and a minority attended a cardiac rehabilitation programme. Those attending were more likely to achieve lifestyle targets, had lower depression and anxiety, and better medication adherence. There is still considerable potential to further reduce cardiovascular risk by increasing uptake and fully integrating secondary prevention and cardiac rehabilitation to provide a modern preventive cardiology programme.
Effectiveness and safety of sofosbuvir/ledipasvir ± ribavirin treatment in liver and/or renal transplant patients with chronic hepatitis C: A single-center experience
Authors: Akin Mete , Buldukoglu Osman Cagin , Adanir Haydar , Suleymanlar Inci , Dincer Dinc , Yildirim Bulent 
Published: June 2018

Objective: Successful treatment is possible with novel direct-acting oral antiviral agents in solid organ transplant patients with hepatitis C. In this study, the effectiveness and safety of sofosbuvir/ledipasvir ± ribavirin treatment in liver and/or renal transplant patients with chronic hepatitis C were evaluated. Materials and methods: A total of 23 liver and/or renal transplant patients who received sofosbuvir/ledipasvir ± ribavirin for chronic hepatitis C over 12 or 24 weeks were enrolled in the study. The treatment response, clinical and laboratory adverse effects, and effect on immunosuppressive drug levels were assessed. Results: A total of 12 patients had undergone renal transplantation and 11 had undergone liver transplantation. All of the renal transplant patients and 91% of liver transplant patients had genotype 1. In total, 10 renal transplant patients and 4 liver transplant patients had treatment experience. Two renal transplant patients and one liver transplant patient had compensated cirrhosis. Nine renal transplant patients were on tacrolimus, and two were on cyclosporine; all of the liver transplant patients were on tacrolimus-based immunosuppressive therapy. While hepatitis C RNA was negative in 75% of renal transplant patients and 91% of liver transplant patients at week 4, it was negative in all of the patients at the end of treatment and 12 weeks after treatment. Significantly reduced hemoglobin levels were observed in patients administered ribavirin during treatment (p = 0.01). There were no significant differences between the baseline and treatment period values of mean creatinine, estimated glomerular filtration rate, bilirubin, and tacrolimus levels. There were no adverse effects leading to treatment discontinuation. Conclusion: Sofosbuvir/ledipasvir ± ribavirin is quite safe and effective in hepatitis C treatment after liver and/or renal transplantation.
M-Kopa Solar: Lighting up the Dark Continent
Authors: Rastogi Charu 
Published: June 2018

M-Kopa Solar is a pay-as-you-go provider of solar home systems, catering to low-income, off-grid customers in East Africa. The company goes by the tagline, ‘Power for Everyone’. Using mobile payments system and an innovative approach to energy delivery, M-Kopa succeeded in building a business which solved a grave problem for the poorest of the poor and has the potential to become a billion dollar enterprise. The case begins with a description of the background in which M-Kopa is operating. It goes on to explain how M-Kopa used the infrastructure gap in sub-Saharan Africa as an opportunity and propagated solar power as an alternative to traditional energy. Finally, it lays out the challenges M-Kopa may face on its expansion spree.
The Professional Retraining Program in Radiotherapy for Medical Physicists
Authors: Черняев А. , Chernyaev A. , Борщеговская П. , Borschegovskaya P. , Варзарь С. , Varzar' S. , Желтоножская М. , Zheltonozhskaya M. , Лыкова Е. , Lykova E. , Нисимов С. , Nisimov S. , Розанов В. , Rozanov V. 
Published: June 2018

The article assesses the personnel situation in the field of domestic radiation therapy and nuclear medicine. Despite the fact that in recent years there has been a significant re-equipping of Russian medical centers with the latest devices, the quantitative indicators of medical equipment normalized for the number of residents of the country are still significantly inferior to the indexes other countries. And this problem is greatly aggravated by the insufficient number of specialists who can work on the equipment supplied. First and foremost, this refer to medical physicists who are responsible not only for ensuring the required accuracy when applying a dose of ionizing radiation to the tumor, but also for ensuring radiation safety when working with sources of ionizing radiation.
A continuing vocational educational retraining program covering development, operation and application of high-tech systems for radiotherapy is being proposed. This program was developed and tested at the Department of Physics of Accelerators and Radiation Medicine of the Physical Faculty of M.V. Lomonosov Moscow State University with the support of the Rusnano Foundation for Educational Programs.
The co-executors in the development and approbation of the Program were the National Medical Research Center of Radiology, A.I. Burnasyan Federal Medical Biophysical Center of the FMBA of Russia. Invited experts in the process of developing the Program were scientists and specialists of the Bauman MSTU, Tomsk Polytechnic University, NRNU MEPhI, N.N. Blokhin National Medical Research Center of Oncology. As a result of a professional educational program, the necessary professional skills for working as specialists in radiotherapy units and nuclear medicine centers are formed, which will successfully solve the problem of professional human resources for the clinical centers of Russia.
The program was developed and successfully implemented at the Department of Physics of Accelerators and Radiation Medicine of the Physics Department of M.V. Lomonosov Moscow State University.
The need to develop a program of assessment of medical physicists, which are working at the moment, is being considered. This will guarantee a high level of knowledge necessary for full participation in the medical process and making responsible decisions on the therapeutic use of radiation devices and ensuring radiation safety of patients and personnel.
Inverse Optimization: Closed-Form Solutions, Geometry, and Goodness of Fit
Authors: Chan Timothy C. Y. , Lee Taewoo , Terekhov Daria 
Published: June 2018

In classical inverse linear optimization, one assumes that a given solution is a candidate to be optimal. Real data are imperfect and noisy, so there is no guarantee that this assumption is satisfied. Inspired by regression, this paper presents a unified framework for cost function estimation in linear optimization comprising a general inverse optimization model and a corresponding goodness-of-fit metric. Although our inverse optimization model is nonconvex, we derive a closed-form solution and present the geometric intuition. Our goodness-of-fit metric, ρ, the coefficient of complementarity, has similar properties to R2 from regression and is quasi-convex in the input data, leading to an intuitive geometric interpretation. While ρ is computable in polynomial time, we derive a lower bound that possesses the same properties, is tight for several important model variations, and is even easier to compute. We demonstrate the application of our framework for model estimation and evaluation in production planning and cancer therapy. This paper was accepted by Yinyu Ye, optimization.
Signal Incongruence and Its Consequences: A Study of Media Disapproval and CEO Overcompensation
Authors: Vergne JP , Wernicke Georg , Brenner Steffen 
Published: June 2018

We draw on the signaling and infomediary literature to examine how media evaluations of CEO overcompensation (a negative cue associated with selfishness and greed) are affected by the presence of corporate philanthropy (a positive cue associated with altruism and generosity). In line with our theory on signal incongruence, we find that firms engaged in philanthropy receive more media disapproval when they overcompensate their CEO, but they are also more likely to decrease CEO overcompensation as a response. Our study contributes to the signaling literature by theorizing about signal incongruence and to infomediary and corporate governance research by showing that media disapproval can lead to lower executive compensation. We also reconcile two conflicting views on firm prosocial behavior by showing that, in the presence of incongruent cues, philanthropy can simultaneously enhance and damage media evaluations of firms and CEOs. Taken together, these findings shed new light on the media as agents of external corporate governance for firms and open new avenues for research on executive compensation. The online appendices are available at https://doi.org/10.1287/orsc.2018.1209 .
Prophylactic antibiotics in soft-tissue procedures in children with cerebral palsy
Authors: Perotti L. R. , Abousamra O. , Rogers K. J. , Miller F. , Sees J. P. 
Published: June 2018

Purpose Data on the benefits of perioperative prophylactic antibiotics in the paediatric population are lacking. In this study, we aimed to assess the rate of infection after isolated soft-tissue procedures in patients with cerebral palsy with and without preoperative prophylactic antibiotics between 2009 and 2015. Methods We reviewed the records of all children with cerebral palsy who underwent isolated soft-tissue procedures (on the upper and lower limb) at our hospital between 2009 and 2015. Children with at least 30-day postoperative follow-up were included. Children who had groin incisions were excluded. Results Two groups were identified: the antibiotic group (77 children with 203 incisions and 343 procedures) had one surgical site infection; the no-antibiotic group (48 children with 102 incisions and 177 procedures) had no surgical site infections. Conclusion These results suggest that the use of preoperative antibiotics does not change the rate of postoperative surgical site infections. Level of Evidence Level III therapeutic study