bluuebunny/crossref_metadata_2025_split huggingface dataset:
INTERNATIONAL MULTICENTER EXPERIENCE IN THE TREATMENT OF INVASIVE ASPERGILLOSIS IN IMMUNOCOMPROMISED CANCER PATIENTS
Authors: Hachem R. , Batista Marjorie , Kanj Souha S , El Zein Saaed , Haddad Sara , Jiang Ying , Mori Nobuyoshi , Vanderson Rocha , Chaftari Anne-Marie , Raad Issam I 
Published: January 2019

BACKGROUND: Invasive aspergillosis (IA) is a life-threatening infection in immunocompromised patients. In this study, we compared the efficacy of voriconazole containing regimen vs non-voriconazole containing regimen in patients with IA.
METHODS: In this retrospective study, we reviewed the medical records of all immunocompromised cancer patients diagnosed with proven or probable IA between February 2012 and March 2018. This trial included 26 patients from the American University of Beirut, Lebanon, 20 patients from Hospital das Clinicas da Faculdade de Medicina, Universidade de São Paulo, Brazil, and 10 patients from St. Luke's International Hospital Tokyo, Japan.
RESULTS: A total of 56 patients were analyzed. They were divided into 2 groups voriconazole containing regimen and non-voriconazole containing regimen (90% Amphotericin B based regimen) . Both groups had similar characteristic, age, gender, and immunocompromised status. The majority of patients had underlying leukemia 53%, lymphoma 18%, myeloma 15% and solid tumor 13%. Antifungal primary therapy with voriconazole-containing regimen was associated with better response to treatment (P = 0.003). Survival analysis showed that primary therapy with a voriconazole containing regimen was significantly associated with improved survival (p =0.006). By multivariate logistic regression analysis, mechanical ventilation was predictor of worse outcome (poor response to therapy and increased mortality at 6 weeks), whereas primary treatment with voriconazole containing regimen was associated with improved outcome (OR=0.14; 95% CI 0.03-0.64, P=0.01).
CONCLUSIONS: Based on international experience in immunocompromised cancer patients with IA, primary therapy with voriconazole-containing regimen is associated with improved response and survival compared with non-voriconazole amphotericin B based regimen.
Flipped Classroom in an Orthopaedic Assessment Course: Students' Perspective
Authors: Bates Dana K. 
Published: January 2019

Context:The flipped classroom, moving lecture outside class time and homework to the classroom, has been researched widely across many disciplines. Athletic training education has little research investigating this pedagogical approach.Objective:To explore students' perceptions of a flipped orthopaedic assessment course.Design:Qualitative study using a phenomenological approach.Setting:Focus group interviews with undergraduate students enrolled in an orthopaedic assessment course.Patients or Other Participants:Students (N = 15) enrolled in either the Physical Exam of the Lower Extremities in Athletic Training or the Physical Exam of the Upper Extremities in Athletic Training course participated in a focus-group interview in January or April 2016.Main Outcome Measure(s):Focus group interviews were conducted with a structured interview protocol. Interview data were analyzed inductively to uncover dominant themes by first organizing the data, then summarizing it into codes, and finally interpreting. Credibility was secured through member checking, triangulation, and investigator triangulation.Results:Themes indicated that participants in a flipped classroom found that this pedagogical practice was helpful, allowed for repetition, initially created more work, and was self-paced.Conclusions:Evidence demonstrated that the flipped classroom for this orthopaedic assessment course was favorably received by the participants.
Care Across Campus: Athletic Training, Nursing, and Occupational Therapy Student Experiences in an Interprofessional Simulation
Authors: Morrell Briyana L. M. , Nichols Alison M. , Voll Craig A. , Hetzler Kathleen E. , Toon Jane , Moore Elizabeth S. , Moore Shannon M. , Kemery Stephanie R. , Carmack Jennifer N. 
Published: January 2019

Context:
This study explored health care students' experiences after participation in an interprofessional simulation. Interprofessional education incorporates students from several health care professions in a controlled, collaborative learning environment. Athletic training students are not well represented in interprofessional education literature.

Objective:
This study sought to explore the attitudes of athletic training, nursing, and occupational therapy students toward other professions after their participation in an interprofessional simulation.

Design:
This article describes the results of the qualitative portion of a mixed-methods study. Focus group discussions related to elements of the Interprofessional Attitude Scale to explore participants' attitudes toward other professions. Researchers analyzed transcribed focus group discussions for themes.

Setting:
This study occurred in a private midsized Midwestern university.

Patients or Other Participants:
Seventy-nine students, representing athletic training, nursing, and occupational therapy, participated in the simulation; a sample of 13 of these participated in the focus groups.

Intervention(s):
Students in all professions cared for or observed the care of a standardized patient from the time of a spinal cord injury on the football field through an ambulance ride and subsequent emergency and inpatient care. Students collaborated and communicated with one another. Faculty conducted debriefing after the simulation and before the focus groups.

Main Outcome Measure(s):
Focus groups included relevant questions from the Interprofessional Attitudes Scale, and themes were identified from participants' responses.

Results:
Researchers identified 4 themes from the focus group discussions: collaboration, respect, knowledge of other professions, and communication. These themes also mirror elements of the Interprofessional Education Collaborative's core competencies of interprofessional collaborative practice.

Conclusions:
After the simulation, students expressed positive attitudes toward other professions. This study suggests that athletic training, nursing, and occupational therapy students have positive attitudes toward each other's professions after an interprofessional simulation activity.
Revista Manuscritos: nuevas formas de resistencia durante la Dictadura chilena
Authors: Zamorano Díaz César 
Published: January 2019

Este trabajo se propone comprender las coordenadas políticas y culturales en las que se inscribe la aparición del único número de la revista Manuscritos(1975). Articulada en un espacio asediado por la represión militar, Manuscritoscanaliza formas de producción artística en conjunto con una escritura que la resignifica. De este modo, la novedad de su construcción escrito-visual se enmarca al interior de una tradición por medio de una filiación con un pasado, funcionando como dispositivo actualizado de resistencia, al recodificar el espacio y el tiempo, lo que en el contexto de tabula rasa dictatorial se tornan inquietantes y subversivos.
Comparing sign language and gesture: Insights from pointing
Authors: Fenlon Jordan , Cooperrider Kensy , Keane Jon , Brentari Diane , Goldin-Meadow Susan 
Published: January 2019

How do the signs of sign language differ from the gestures that speakers produce when they talk? We address this question by focusing on pointing. Pointing signs play an important role in sign languages, with some types functioning like pronouns in spoken language (e.g., Sandler &amp; Lillo-Martin 2006). Pointing gestures, in contrast, are not usually described in linguistic terms even though they play an important role in everyday communication. Researchers have focused on the similarities between pointing in signers and speakers (e.g., Cormier et al. 2013), but no studies to date have directly compared the two at a fine-grained level. In this paper, we compare the formational features of 574 pointing signs produced by British Sign Language signers (BSL Corpus) and 543 pointing gestures produced by American English speakers (Tavis Smiley Corpus) with respect to three characteristics typically associated with language systems: conventionalization, reduction, and integration. We find that, although pointing signs and pointing gestures both exhibit regularities of form, pointing signs are more consistent across uses, more reduced, and more integrated into prosodic structure than pointing gestures. Pointing is thus constrained differently when it is produced along with a signed language vs. when it is produced along with a spoken language; we discuss possible sources of these constraints.
Law, Imagination and Poetry. Using Poetry as a Means of Learning. Special Issue on Active Learning and Teaching in Legal Education
Authors: de Vries Bald 
Published: January 2019

Law, Imagination and Poetry. Using Poetry as a Means of Learning. Special Issue on Active Learning and Teaching in Legal Education
This article builds upon the work of James Boyd White as well as on Shelley’s ‘A defence of Poetry’ (1840) and reports upon an experiment in which students use poetry as a means to understand philosophical texts. The experiment had a double goal: first, I sought to challenge students in reading a philosophical text differently with an aim to better understand the text. The second goal was to challenge students to think about the text differently, more critically and analyse its relevance for the contemporary world. In the end, using imagination, is the claim, contributes to students finding their own ‘voice’.
Effects of surface treatments on the bond strength of glass hybrid restorative system repaired with hybrid composite resin
Authors: Arıcıoğlu Banu , Hatipoğlu Ömer 
Published: January 2019

Aim: To assess the bonding strength of the Equia Forte resin modified glass ionomer cement to the hybrid composite material by applying different surface treatments.
Methodology: 140 samples as 70 Equia Forte and 70 G-eanial composites were produced as 8 mm diameter 3 mm high cylindrical standardized samples. The samples were divided into 7 groups to treat surfaces. G-eanial composite resins as 4 mm diameter 3 mm high was placed onto the samples and polymerized. Then 1000 thermal cycle was applied and samples were mounted in the universal testing machine. Obtained bond strength values were recorded as Newton. One way Anova and Scheffe post hoc tests were performed for statistics.
Results: In the G-aenial group, the highest bond strength was obtained with laser-bond method (N=17.71, P<0.05) and the lowest bonding strength was obtained with only laser-treated method (N=3.45, P<0.05). In the Equia group, the highest bond strength was obtained with air abrasion-bond method (N=9.29, P<0.05) and the lowest bonding strength was obtained with only laser-treated method (N=0.00, P<0.05).
Conclusion: The fact that sufficient bond strength could not be reached by any surface treatment in Equia Forte may suggest that replacing the Equia Forte instead of repairs may be a better choice.
Standardsetting av læringsstøttende prøver i engelsk for Vg1
Authors: Moe Eli , Helness Hildegunn Lahlum , Grocott Craig , Verhelst Norman 
Published: January 2019

Formålet med denne artikkelen er å beskrive framgangsmåten som ble brukt for å bestemme kuttskårer (grenser) mellom tre nivåer i Det europeiske ramme-verket for språk (A2, B1 og B2) på to læringsstøttende lytteprøver i engelsk for Vg1-elever. Målet har vært å undersøke om det er mulig å etablere enighet om kuttskårene, og om standardsetterne som deltok i arbeidet fikk tilstrekkelig opp-læring på forhånd. Videre var det et mål å se på hvilke konsekvenser kuttskårene vil få for fordeling av elever på de ulike rammeverksnivåene. Standardsettingen ble gjennomført med utgangspunkt i pilotdata fra 3199 elever på Vg1, Cito-metoden og 16 panelmedlemmer med god kjennskap til Rammeverkets nivåer. Flere av panelmedlemmene var eller hadde vært lærere i engelsk for elever på 10. trinn eller Vg1. Cito-metoden fungerte bra for å etablere kuttskårer som standardsetterne var forholdsvis enige om. Sluttresultatene viser at målefeilen var relativt liten. Resultatene viser større enighet om kuttskåren mellom nivåene B1 og B2 enn mellom A2 og B1, og dette kan ha en sammenheng med at det ble brukt mer tid på forberedelsesarbeid for B1 og B2. Lærere i panelet som kjenner elevgruppa godt, mener at konsekvensen kutt-skåren har for fordeling av elever på de ulike rammeverksnivåene, stemmer med deres egen vurdering av elevenes lytteferdigheter.Nøkkelord: standardsetting, testsentrert metode, Cito-metoden, standard, kutt-skår, vippekandidatStandard setting for English tests for 11th grade students in NorwayAbstractThis article presents the process used to determine the cut scores between three levels of the Common European Framework of Reference for languages (A2, B1 and B2) for two English listening tests, taken by Norwegian pupils at the 11th grade. The aim was to establish whether agreement can be reached on cut scores and whether the standard setters received enough preparation before the event. Another aim was to examine the potential consequences the cut scores would have for the distribution of pupils across the different levels. The standard setting took place using pilot data from 3199 pupils, the Cito method and 16 panel members with a good knowledge of the framework levels. Some panel members were or had been 10th or 11th grade English teachers. The Cito method worked well for establishing cut scores with which the panel members mostly agreed. The results indicated a small margin of error. The results showed a higher level of agreement for the cut score between B1 and B2 than between A2 and B1, possibly connected to the longer preparation time dedicated to B1 and B2. Teachers on the panel with good knowledge of the pupil base believe that the consequences these cut scores have for the distribution of pupils, correlate with their own experiences of pupils' ability.Keywords: standard setting, test-centered method, the Cito method, standard, cut score, borderline person / minimally competent user
«I utgangspunktet velger vi lignelser som er sentrale» «Kjernens» kostnad i trosopplæringens lignelseslæring
Authors: Reinertsen Ellen Aasland 
Published: January 2019

Tre lignelser går igjen i trosopplæringen i Den norske kirke. Disse tre lignelsene gjentas ofte – av og til mange ganger – for de samme barna. Lignelsene er Den barmhjertige samaritan, Sauen som ble funnet og En far som ventet. Dette fant jeg i en spørreundersøkelse besvart av ansatte som jobber med trosopplæring. Studien ser også visse tendenser i begrunnelsene for at nettopp disse lignelsene er med. Tendensene er at de tre regnes som «sentrale» og «enkle». Artikkelen presenterer og diskuterer disse funnene.Temaord: Trosopplæring, lignelser, hermeneutikk, tolkning, kjønn, interseksjonalitet, sentralitet, kateketikk, barn, unge, bibel, bibelresepsjon, karakterer, livstolkning, livsmestring. Abstract:Three parables are dominant in the Christian education in the Church of Norway. The parables, The good Samaritan, The lost (and found) sheep, and An awaiting father, are taught to children and young people by nearly all congregations. And more than that, they are often repeated several times for the same youngsters. This article presents and discusses findings from a questionnaire about parables in Christian education in the Church of Norway. In the survey, I ask why these three parables are so dominant and so often repeated. The study finds two main arguments: These parables are understood as «central» and «simple».Keywords: Christian education, parables, hermeneutics, gender, intersectionality, centrality, catechism, children, young people, bible, bible reception, characters, meaning, interpretation, life skills.
O espaço como caracterização da personagem feminina na obra Atire em Sofia, de Sonia Coutinho
Authors: Alves Lopes Nemia Ribeiro , Ribeiro Lopes de Almeida Edwirgens Aparecida 
Published: January 2019

A trajetória da narrativa brasileira foi marcada por representações urbanas como espaço de atuação, predominantemente, masculino, ficando legado à mulher o espaço doméstico. Entretanto, na contramão dessa vertente, Sonia Coutinho confere às suas personagens femininas um olhar amplo sobre paisagens, cidades, casas, construindo uma diferenciada representação do urbano. A relação entre a mulher e o espaço nos conduz à compreensão acerca da relevância do meio social para a construção identitária feminina. Sendo assim, este trabalho discute a representação da cidade-personagem, da paisagem e da metáfora do labirinto no romance “Atire em Sofia”, de Sonia Coutinho, como elemento de ruptura com o padrão tradional de representação do urbano e como caracterização da mulher em relação ao espaço em que está inserida. PALAVRAS-CHAVE: Cidade. Paisagem. Mulher. Labirinto.
Routine Broad-Range Fungal Polymerase Chain Reaction With DNA Sequencing in Patients With Suspected Mycoses Does Not Add Value and Is Not Cost-Effective
Authors: Stempak Lisa M. , Vogel Sherilynn A. , Richter Sandra S. , Wyllie Robert , Procop Gary W. 
Published: January 2019

Context.—
New molecular diagnostic tests regularly become available, and they may be assumed to be superior to traditional diagnostic studies. The added cost of these studies should be considered in conjunction with the value provided for patient care.

Objective.—
To assess the cost and diagnostic value of broad-range polymerase chain reaction (PCR) and DNA sequencing for the diagnosis of fungal infections compared with traditional studies.

Design.—
We reviewed the cost and clinical impact of broad-range fungal PCR/DNA sequencing for 65 specimens for which this test, a direct fungal examination, fungal culture, and a histopathologic assessment were performed.

Results.—
The sensitivity, specificity, and positive and negative predictive values for each of the assays studied were, respectively: histopathology (83.3%, 100%, 100%, and 98.3%); direct examination (66.7%, 100%, 100%, and 96.7%); fungal culture (83.3%, 100%, 100%, and 98.3%); and broad-range fungal PCR/DNA sequencing (83.3%, 95.0%, 62.5%, and 98.3%). The cost for broad-range fungal PCR/DNA sequencing was $32,500, compared with $8,591.70 for all traditional tests combined, for the 65 specimens included in this review.

Conclusions.—
Broad-range fungal PCR/DNA sequencing did not detect any infecting fungal pathogen that was not detected by at least 1 of the traditional methods, but 3 false-positives occurred. Broad-range fungal PCR/DNA sequencing is not a substitute for traditional laboratory studies and should be used judiciously to promote care affordability.
Cutaneous Metastases: A Review and Diagnostic Approach to Tumors of Unknown Origin
Authors: Habermehl Gabriel , Ko Jennifer 
Published: January 2019

Context.—Cutaneous metastases from a distant malignancy are a diagnostic challenge for pathologists. Secondary involvement of the skin by a metastatic process portends a much worse clinical prognosis than any primary cutaneous malignant mimickers. Immunohistochemical staining methods continue to evolve and are of paramount importance in diagnosis.Objective.—To review the clinical, histopathologic, and immunohistochemical staining patterns for commonly encountered entities and discuss potential pitfalls in diagnosis. A practical guide useful in approaching cutaneous metastases of unknown primary is outlined.Data Sources.—An extensive search and review of literature in PubMed was performed, processed, and condensed.Conclusions.—Cutaneous metastases have broad histopathologic patterns. They are nearly always dermal based, with an overall foreign appearance. They can be single papules/nodules or multiple in number, mimicking an inflammatory or infectious process. Ultimately, immunohistochemistry remains an essential diagnostic tool, and clinical correlation is paramount in the workup of these entities.
Atypical Squamous Cells of Undetermined Significance Cervical Cytology Report Rate and Histologic Follow-up Findings From the Largest College of American Pathologists–Certified Laboratory in China
Authors: Zheng Baowen , Yang Huaitao , Li Zaibo , You Jia , Wei Guijian , Zhang Huina , Zeng Zhengyu , Xie Fengxiang , Zhao Chengquan 
Published: January 2019

Context.—Reports for atypical squamous cells of undetermined significance (ASC-US) and histologic findings are rare in China.Objective.—To analyze the correlation findings of ASC-US cytology with high-risk human papillomavirus (hrHPV) test and histopathologic follow-ups.Design.—ASC-US cases with hrHPV test and histologic follow-ups between 2011 and 2015 were analyzed at a College of American Pathologists–certified laboratory.Results.—A total of 2 206 588 Papanicolaou (Pap) tests were performed, including 1 513 265 liquid-based cytology preparations (68.58%), and 693 323 conventional Pap tests (31.42%). The overall ASC-US reporting rate was 3.77% (83 199 of 2 206 588), with the highest in women aged 40 to 49 years. Of 18 574 women with ASC-US Pap and HPV testing, the hrHPV positivity rate was 34.98% (6498 of 18 574) with the highest in women younger than 30 years. A total of 6012 women with ASC-US Pap test findings had histologic follow-ups within 6 months; the overall cervical intraepithelial neoplasia 2 and above (CIN2+) detection rate was 7.87% (473 of 6012). One thousand nine hundred nine women with ASC-US Pap and HPV testing had histologic results. CIN2+ lesion was found in 13.98% (124 of 887) of women with ASC-US Pap/HPV-positive test results, significantly higher than 2.84% (29 of 1022) for women with ASC-US Pap/HPV-negative test results. Cervical squamous cell carcinoma was found in 3.95% (35 of 887) of women with ASC-US/HPV-positive test results.Conclusions.—This is one of the largest studies to investigate HPV and histologic follow-up findings in women with ASC-US in China. The ASC-US reporting rate, HPV positivity rate, and CIN2+ detection rate were all within the currently recognized benchmark ranges. These findings may contribute to establishing a baseline for better understanding of the status of cervical screening in China.
Creating a knowledge-sharing community: The use and expansion of knowledge management at Tulsa Community College
Authors: Taylor Andy K. 
Published: January 2019

Knowledge management (KM) is a very nebulous term. Research on the use of KM across different types of organizations and disciplines confirms this. This article examines the path that Tulsa Community College (TCC) took to not only build the use of KM across the college, but also to create the support structure to foster the creation of a knowledge sharing community.In order for an institution to be able to use KM effectively, several questions should be asked. Is there a culture of knowledge sharing at the institution? Is the concept of KM supported by those in the administration?In the case of TCC, the answers to these questions showed that there were a number of factors that precipitated the use of KM. First, the college began a complete reorganization of its academic units because, as a multicampus community college system, the academic units had become self-contained. A reorganization was carried out that greatly benefited the institution and brought it more in line with a “One College” model.