bluuebunny/crossref_metadata_2025_split huggingface dataset:
MUSCLE ACTION, BONE RAREFACTION AND BONE FORMATION
Authors: Geiser Max , Trueta Joseph 
Published: February 2018

1. In five series of experiments in eighty-two rabbits we succeeded in causing rarefaction of the calcaneum of all the animals soon after it was relieved from muscular compressing forces; new bone was generated when the calcaneum was subjected again to the stresses and strains of muscle contraction. 2. We found evidence that during muscle action pressure forces are transmitted through the bone, and that the presence or absence of these pressure forces conditions the balance between bone formation and bone removal. 3. In the calcaneum of the rabbit lack of muscular action seems to be the most important factor inducing osteoporosis. It is possible that the origin of post-traumatic osteoporosis has the same basis. 4. In our experiments bone rarefaction was characterised by a great increase in the vascularity of the bone; this increase ceased when the bone reached its final precarious bone density. Thus, vascular over-activity accompanied the removal of bone; but bone reconstruction was also seen to be accompanied by a more localised increase in vascularity. 5. From our experiments we cannot suggest that the inhibition of muscle contraction accompanying Sudeck's syndrome is responsible for this disorder, because we were unable in our animals to cause any of the other signs characteristic of Sudeck's bone atrophy. But the constancy with which we caused bone atrophy by the removal of muscle action may possibly help to explain the mechanism of bone absorption accompanying Sudeck's disease.
OSTEOPOROSIS OF UNKNOWN CAUSE IN YOUNGER PEOPLE
Authors: Jackson W. P. U. 
Published: February 2018

1. The syndrome of osteoporosis is reviewed and its various causes are mentioned. Osteoporosis in youngish patients without any demonstrable cause is referred to as "idiopathic." The scant literature on this condition is reviewed. Its clinical, radiological, biochemical and histological features are considered. 2. A series of thirty-eight cases is analysed, and illustrative case histories are described. The peculiarities of the disease as it is seen in women are discussed, particularly the relationship to pregnancy and lactation, which appear to act as precipitating factors, rather than being primarily causative. 3. The differential diagnosis is discussed. Osteogenesis imperfecta may not always be easy to distinguish; since it is really a "congenital osteoporosis" this is hardly surprising. 4. The following possible etiological factors are propounded (apart from pregnancy): nutritional, occupational, lack of sex hormone, liver dysfunction, loss of protein, diabetes, premature ageing, hypophosphatasia, "alarm reaction," and inheritance. None of them can be incriminated except in the odd case. The relationship between osteoporosis and idiopathic hypercalcuria is mentioned. The only conclusion regarding etiology is that some people are simply more prone to bone loss than are others, and in these a variety of accentuating factors may render the disorder clinically apparent. 5. The treatment of the condition is unsatisfactory, although occasionally a positive calcium balance may be obtained with sex hormones or intravenous infusion of plasma albumin or whole plasma. The general tendency seems to be towards clinical improvement (biologically "stabilisation" rather than improvement), but some patients become permanently crippled.
HALLUX RIGIDUS IN THE ADOLESCENT
Authors: Kessel Lipmann , Bonney George 
Published: February 2018

1. The etiology of hallux rigidus has been studied by an examination of ten adolescent and four adult patients. 2. Although osteochondritis dissecans of the metatarsal head has been seen in two cases, our evidence generally suggests that metatarsus primus elevatus is the important etiological factor in established hallux rigidus. 3. The common factor for the production of symptoms is the limitation of dorsiflexion of the first metatarso-phalangeal joint, just as the key to treatment is the existence of a good range of plantar-flexion of the joint. 4. The technique and results of the operation of phalangeal extension osteotomy for hallux rigidus are given.
LAMBRINUDI'S ARTHRODESIS
Authors: MacKenzie I. G. 
Published: February 2018

One hundred cases of Lambrinudi's arthrodesis are reviewed. The shortest follow-up was one year. and the longest twenty-seven years. Thirty-seven per cent were successful. Nineteen per cent were failures; many of these were associated with faulty technique, and one method of operation which gives good results is described. Success is likely if there is a balance of power between the dorsiflexors and plantarflexors of the ankle, especially if there is some fixed equinus before operation. Success is less likely when the operation is done for a flail foot. In such circumstances arthrodesis of the ankle may have to be considered subsequently for instability of the lateral ligament, recurrence of dropfoot, or arthritis which may develop in the more active patients. Age in itself is no bar to success, but pseudarthrosis is more likely to occur in patients over the age of twenty.
A FURTHER REVIEW OF THE RESULTS OF OPERATIONS ON THE HIP JOINT
Authors: Shepherd Margaret M. 
Published: February 2018

General remarks–Comparison of the two reviews shows that patients with good results return more readily for a review than those with poor results. In middle-aged patients with some disability for walking an attendance of 80 per cent at least is necessary in order to obtain a representative follow-up five to ten years after operation. An outstanding feature of all the operations reviewed is the degree of lasting relief of pain. It is rare to find that a patient with severe hip pain before operation has pain of the same severity after any of these operations at least up to ten years afterwards, and probably for much longer. Generally speaking, although in advancing years stiffness of the hip is undoubtedly a handicap, it is preferable to instability, particularly if this is progressive. A patient can adapt himself to and accept a disability that is permanent and unaltering, but instability increasing in later years can be distressing mentally and incapacitating physically. Cup arthroplasty–There is an element of unpredictability in the results, especially the late results, of cup arthroplasty. Movement decreases and there is a tendency for pain and instability to increase after four or five years. There is little to indicate which case will be successful although the results vary according to the condition for which operation is performed. The operation gives good results, on the whole, for osteoarthritis, particularly when the operation is done on one hip only. Stability is much more important when both hips are involved, and, unless this is good in at least one hip, the results of bilateral operations are poor. "Excellent" results are not obtained in rheumatoid arthritis but few results are "poor." Operations for congenital dislocation of the hip give the most disappointing results. In operations for ankylosing spondylitis there is a high incidence of stiffening of the hip, but many patients are greatly improved in comparison to their state before operation. Displacement osteotomy–The hazard in displacement osteotomy is ankylosis, particularly when internal fixation is not used. Relief of pain and stability are well maintained. The results in general, and for pain in particular, are less good when internal fixation is used. Adduction of the upper fragment of the femur appears to be of value in the production of a good result. In the series examined it was less often achieved when internal fixation was the method of immobilisation. The best results were obtained in cases of congenital dislocation of the hip and there were few "poor" results in cases of congenital subluxation. Excision of the head and neck of the femur and Batchelor's operation–Rehabilitation may take a long time, but the late results are more predictable than in the other operations reviewed. A "fair" result is more likely than an "excellent" one, but late "poor" results are few. Relief of pain is better after excision of the head and neck than after any other operation reviewed.
CONGENITAL DISLOCATION OF THE HIP
Authors: MacKenzie I. G. , Seddon H. J. , Trevor D. 
Published: February 2018

1. The results of treatment of 134 patients with congenital dislocation of 167 hips are reviewed. 2. Late diagnosis is still a major problem. 3. Subluxations rarely give rise to poor results, but in dislocations first treated over the age of five years there is a one-in-three risk of failure. 4. Manipulative reduction is successful less often than reduction on a frame and carries a higher risk of avascular necrosis. 5. Closed reduction on a frame was satisfactory in 58 per cent of patients under the age of three years, and can succeed up to the age of five. 6. Open reduction was required in 20 per cent of cases under the age of three, and can be used successfully up to the age of six. 7. Seven anatomical barriers to closed reduction have been recognised and two or more are commonly found in one hip when open reduction is performed. 8. The acetabular roof may fail to develop after reduction, especially if this is delayed. A C.E. angle of under 20 degrees does not necessarily forebode this, unless measured on an arthrograph. Sclerosis of a sloping acetabular roof is an indication for operation. Acetabuloplasty is the proper operation for a sloping acetabulum and can be done successfully up to the age of twelve. Over this age, a shelf operation should be performed; this is appropriate also in younger patients in whom the curvature of the acetabulum is normal but does not extend far enough laterally. These operations were required in 38 per cent of hips treated in patients under the age of three, and in 64 per cent over this age. There is a one-in-three risk of avascular necrosis when acetabular reconstruction is done in patients under three. 9. Anteversion, if excessive, should be corrected by subtrochanteric osteotomy, and any valgus of the femoral neck should be corrected simultaneously. 10. Unilateral dislocations in patients over the age of six are best treated by Colonna's operation. In our few bilateral cases over this age our results have been disappointing. 11. Avascular necrosis is less common but more serious when it occurs over the age of three. Manipulative reduction and the use of frog-leg plasters are two avoidable factors which appear to increase its incidence. The more serious degrees are accompanied by stiffness of the hip, and when this sign is present weight bearing should be avoided. 12. Prolonged, though rarely permanent, limitation of movement occurs in some 10 per cent of cases. In a few, operative correction was required.
RHEUMATOID CYSTS OF THE CALF AND THEIR RELATION TO BAKER'S CYSTS OF THE KNEE
Authors: Maudsley Roy H. , Arden George P. 
Published: February 2018

1. Three cases are described of a calf swelling occurring in rheumatoid arthritis. 2. This condition has been described by Baker, though many of his patients had tuberculous infection of the knee. 3. The diagnosis may present difficulty because of the distance of the swelling from its origin in the knee joint. 4. Excision of the cyst is advised when it causes pain, but recurrence is likely if disease of the joint remains active.
DISLOCATION OF THE PERONEAL TENDONS WITH MARGINAL FRACFURE OF THE LATERAL MALLEOLUS
Authors: Murr Sepp 
Published: February 2018

1. Three patients are described in whom forward dislocation of the peroneal tendons was associated with a chip fracture of the lateral malleolus and forward dislocation of the tendons through the fracture. 2. This injury differs from the more usual simple anterior dislocation of the peroneal tendons in which rupture of the superior peroneal retinaculum allows the dislocation to occur. 3. A simple operation is described which succeeded in holding reduced the dislocated tendons by suturing the fractured small chip of bone back to the lateral malleolus.
A RADIOLOGICAL APPROACH TO THE SUBTALAR JOINT
Authors: Isherwood Ian 
Published: February 2018

The subtalar joint is not easy to visualise by standard radiographic methods. Several projections are described including medial and lateral oblique axial views to demonstrate the three compartments of the joint. It is suggested that when visualisation of the subtalar joint is required these views should be routine. Various conditions affecting the subtalar joint and their demonstration by these oblique axial views are discussed.
A PROLONGED FOLLOW-UP OF PERONEAL SPASTIC FLAT FOOT
Authors: Braddock G. T. F. 
Published: February 2018

1. The radiographic appearances are no guide to prognosis or treatment of peroneal spastic flat foot. 2. Only 10 per cent of peroneal spastic flat feet are likely to cause severe persistent disability. 3. Severe symptomatic tarsal arthritis is exceptional in this condition.
STUDIES ON BONE MATRIX IN NORMAL AND OSTEOPOROTIC BONE
Authors: Little K. , Kelly M. , Courts A. 
Published: February 2018

1. The appearance of decalcified bone matrix in the electron microscope is described. 2. In the matrix two types of collagen fibril have been distinguished. Differences observed are in solubility, x-ray diffraction pattern and appearance. In infant bone the form which appears as fine fibrils predominates. In adult bone the form which appears as tubular fibrils of larger diameter predominates. 3. In bones from elderly subjects the chemical reaction employed to convert collagen into eucollagen sometimes hydrolyses fatty acid esters, and lines due to the free fatty acid are found on the x-ray diffraction patterns of the insoluble residue after citrate extraction. 4. In ancient bones and fossils the stable tubular form of collagen survives, but not the fine fibrils. 5. When decalcified, the matrix in osteoporotic bones loses its architecture and fibrillar form. Under conditions in which only a small fraction is dissolved from normal bone most of the collagen in osteoporotic bone disperses in citric acid. The insoluble residue then gives a modified x-ray diffraction pattern. 6. Evidence has been produced to suggest that the immediate cause of many forms of osteoporosis is some local factor affecting the osteocytes, rather than a general chemical effect.
THE HEALING MECHANISM IN ARTIFICIALLY CREATED CIRCUMSCRIBED DEFECTS IN THE FEMORA OF ALBINO RATS
Authors: Melcher A. H. , Irving J. T. 
Published: February 2018

1. An experimental study of the healing mechanism in circumscribed defects in femora of albino rats of the Wistar strain is described. 2. Only the outer one-fifth of the defect is repaired by subperiosteal bony callus, the rest of the defect being repaired by endosteal callus. 3. Subperiosteal callus does not bridge the defect until endosteal callus is developed fully. 4. As peripheral callus matures the greater part of the endosteal callus is resorbed, with the exception of trabeculae attached to the margin of the defect. 5. The resorbed area in the medullary part of the defect is gradually obliterated by deposition of inner circumferential lamellae. 6. There appear to be differences between the mechanism responsible for repair of fractures of a long bone and that which heals circumscribed bone defects.
PRIME FACTORS IN THE ETIOLOGY OF CONGENITAL DISLOCATION OF THE HIP
Authors: Wilkinson John A. 
Published: February 2018

1. Breech malposition and hormonal joint laxity produce atraumatic posterior dislocations in the hip joints of young rabbits. 2. Experimental studies were shown to cause the development of a limbus and other softtissue changes similar to those found in human congenital dislocations. 3. The development of femoral retroversion and anteversion in the presence of joint laxity is described. 4. The co-existence of breech malposition and hormonal joint laxity in utero, and their importance as prime factors in the etiology of congenital dislocation of the hip, are discussed.
GROWTH AND STRUCTURE OF BONE DISTAL TO AN ARTERIOVENOUS FISTULA: QUANTITATIVE ANALYSIS OF TETRACYCLINE-INDUCED TRANSVERSE GROWTH PATTERNS
Authors: Vanderhoeft Patrick J. , Kelly Patrick J. , Janes Joseph M. , Peterson Lowell F. A. 
Published: February 2018

Puppies in the second half of their growing period have been observed for one and a half to four and a half months after creation of a superficial femoral arteriovenous fistula on the right side. From measurements of the whole bone and from microradiographic and tetracycline-fluorophore studies of the diaphysial bone, it is believed that the following statistically significant phenomena may be attributed to the influence of the arteriovenous fistula. 1. All bones distal to the fistula are influenced in their growth. The tibia and metatarsals become heavier and larger, but retain normal shape. Although stimulation of longitudinal growth is small, it is significant for the tibiae and nearly significant for the femora in these short-term experiments. 2. The histological structure of the bones remains normal but quantitative changes are induced. The compact bone is more porous because of an increased number of osteones. Haversian turnover itself is affected in that the individual formation time of osteones tends to become longer, especially in the metatarsals. 3. Periosteal new bone formation is immediately stimulated, producing a flare of new bone. This accounts for the increase in diaphysial weight in the tibia but not in the metatarsals, where the same effect results from decreased resorption of old bone. 4. Endosteal new bone formation is depressed, especially in the metatarsals, resulting in an enlarged medullary cavity.
FURTHER STUDIES ON THE ETIOLOGY OF CHONDROMALACIA PATELLAE
Authors: Outerbridge R. E. 
Published: February 2018

1 . Current theories of the etiology of chondromalacia patellae do not explain satisfactorily either its great frequency or its common site of origin on the medial patellar facet. 2. The etiology can be more logically explained by the presence of a ridge on the upper anterior border of the cartilage of the medial femoral condyle, in most knees. This ridge, consisting of cartilage, or cartilage and bone, varies considerably in height and, in normal knee joint movement, causes considerable friction on the medial patellar facet. 3. The degenerative changes were found to be greater in the presence of the larger ridges, and–because of longer wear and tear–in the older patients. 4. This study indicates that chondromalacia was more severe in women than in men, and in patients overweight. Although the activity of the individual and the power of the quadriceps mechanism must play an extremely important part in this condition, it was not possible to assess this. 5. Two factors previously considered to be important in the etiology of this condition, namely, the length of the patellar tendon and Wiberg's Type III patellar shape, have not been confirmed in this study. 6. Resulting from the present investigation certain precautions are suggested in rehabilitation after operations on the knee, and a surgical method for discouraging the progress of this common, and sometimes disabling, condition has been devised.
THE MENISCO-FEMORAL LIGAMENTS OF THE HUMAN KNEE
Authors: Heller Leon , Langman Jan 
Published: February 2018

1. The menisco-femoral ligaments, extending from the posterior horn of the lateral meniscus to the lateral aspect of the medial femoral condyle, were found in ninety-nine (71 per cent) of the 140 knees examined. Fifty per cent of the ligaments were identified as the anterior menisco-femoral ligament while the remaining 50 per cent were of the posterior type. 2. During flexion of the knee with the foot fixed the menisco-femoral ligaments pull the posterior horn medially and slightly anteriorly, increasing the congruity between the meniscotibial socket and the lateral femoral condyle. 3. During lateral rotation of the femur with the knee flexed the menisco-femoral ligament pulls the posterior horn medially and slightly anteriorly, in this way increasing the risk of the posterior horn being crushed by the lateral femoral condyle. It is suggested that this is prevented by the contraction of the tibio-meniscal portion of the popliteus muscle which pulls the posterior horn of the lateral meniscus posteriorly. 4. When removing the lateral meniscus it may be advisable to make another incision in order to free the posterior horn from its attachment to the popliteus muscle and then to cut the menisco-femoral ligaments under direct vision.
CONGENITAL FIBROSIS OF THE VASTUS INTERMEDIUS MUSCLE
Authors: Karlen A. 
Published: February 2018

1. The cases of six Chinese children affected by so-called congenital fibrosis of the vastus intermedius muscle are described. The reasons for the choice of name are discussed. 2. Reasons for early operation are put forward: in young children simple division of the tendon of the vastus intermedius is adequate. 3. With increasing age severe changes in all the joint tissues occur, notably in the articular cartilage of the patella. These changes are likely to vitiate the result after operation. 4. The importance of getting as much flexion as possible in children of Asiatic race is stressed.
TIBIALIS SPASTIC VARUS FOOT WITH TARSAL COALITION
Authors: Simmons Edward H. 
Published: February 2018

1. Tarsal coalition often presents with the clinical picture of a peroneal spastic flat foot, but may present with a painful varus foot and spasm of the tibial muscles. 2. Three cases of tibialis spastic varus foot are described with a calcaneo-navicular bar as the associated anomaly. 3. Complete excision of the bar with interposition of the origin of the extensor digitorum brevis muscle appears to be a satisfactory method of treatment when carried out at a sufficiently early age.
COMPARATIVE RADIOLOGICAL STUDY OF THE SPINES OF A PRIMITIVE POPULATION WITH NORTH AMERICANS AND NORTHERN EUROPEANS
Authors: Fahrni W. Harry , Trueman Gordon E. 
Published: February 2018

1. On the basis of radiographic studies the incidence of degenerative change in the intervertebral disc in primitive squatting populations is considerably less than that found in civilised peoples. 2. The suggestion is made that lordosis is implicated in the pathogenesis of degeneration, but further studies are required.
THE ETIOLOGY OF FEMORAL EPIPHYSIAL SLIPPING
Authors: Alexander Colin 
Published: February 2018

1. The hypothesis is advanced that the fundamental lesion of epiphysiolysis is a slow posterior growth migration of the head on the neck. 2. It is suggested that this is unrelated to the erect posture or to any abnormality of the growth cartilage. 3. Sitting stresses are measured and are postulated as the likely cause of the growth deviation. 4. The result of the deviation is an increase in the shear stress component; in the erect posture clinical epiphysiolysis is regarded as a simple fracture occurring in a proportion of deviated cases when the increased shear component exceeds the critical level appropriate to the individual. 5. It is suggested that this hypothesis explains the age and sex incidence, the left predominance, the reduced epiphysial angle found on the uninvolved hip and the clinical and radiological evolution of the disorder.
RECURRENT DISLOCATION OF THE ELBOW
Authors: Osborne Geoffrey , Cotterill Paul 
Published: February 2018

1. Recurrent dislocation of the elbow is caused primarily by collateral ligament laxity with secondary damage to the capitulum and head of radius. 2. The pathological changes resemble those of recurrent dislocation of the shoulder. 3. Subluxation or instability of the radial head is often associated with capsular ossification and deserves wider recognition because it may be confused with osteochondritis dissecans. 4. A simple method of soft-tissue repair has successfully prevented redislocation of eight elbows.