bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inferring Tumour Proliferative Organisation from Phylogenetic Tree Measures in a Computational Model
Authors: Scott Jacob G. , Maini Philip K. , Anderson Alexander R. A. , Fletcher Alexander G. 
Published: May 2018

ABSTRACTWe use a computational modelling approach to explore whether it is possible to infer a tumour’s cell proliferative hierarchy, under the assumptions of the cancer stem cell hypothesis and neutral evolution. We focus on inferring the symmetric division probability for cancer stem cells in our model, as this is believed to be a key driving parameter of tumour progression and therapeutic response. Given the advent of multi-region sampling, and the opportunities offered by them to understand tumour evolutionary history, we focus on a suite of statistical measures of the phylogenetic trees resulting from the tumour’s evolution in different regions of parameter space and through time. We find strikingly different patterns in these measures for changing symmetric division probability which hinge on the inclusion of spatial constraints. These results give us a starting point to begin stratifying tumours by this biological parameter and also generate a number of actionable clinical and biological hypotheses including changes during therapy, and through tumour evolution.
Gamete fusion rapidly reconstitutes a bi-partite transcription factor to block re-fertilization
Authors: Vještica Aleksandar , Merlini Laura , N’kosi Pedro , Martin Sophie G 
Published: May 2018

AbstractThe ploidy cycle, integral to sexual reproduction, requires not only meiosis to halve the number of chromosomes, but also mechanisms that ensure zygotes are formed by exactly two partners1–5. During sexual reproduction of the fungal model organismSchizosaccharomyces pombe, haploid P- and M-cells normally fuse to form a diploid zygote that immediately enters meiosis6. Here, we reveal that fast post-fusion reconstitution of a bi-partite transcription factor actively blocks re-fertilization. We first identify mutants that undergo transient cell fusion involving cytosol exchange but not karyogamy, and show this drives distinct cell fates in the two gametes: The P-partner undergoes lethal, haploid meiosis while the M-cell persists in mating. Consistently, we find that the zygotic transcription that drives meiosis is initiated rapidly only from the P-parental genome, even in wild type cells. This asymmetric gene expression depends on a bi-partite complex formed post-fusion between the nuclear P-cell-specific homeobox protein Pi and a cytosolic M-specific peptide Mi7,8, which is captured by Pi in the P-nucleus. Zygotic transcription is thus poised to initiate in the P-nucleus as fast as Mi reaches it. The asymmetric nuclear accumulation is inherent to the transcription factor design, and is reconstituted by a pair of synthetic interactors, one localized to the nucleus of one gamete and the other in the cytosol of its partner. Strikingly, imposing a delay in zygotic transcription, by postponing Mi expression or deleting its transcriptional target in the P-genome, leads to zygotes fusing with additional gametes, thus forming polyploids and eventually aneuploid progeny. We further show that the signaling cascade to block re-fertilization shares components with, but bifurcates from, meiotic induction9–11. Thus, cytoplasmic connection upon gamete fusion leads to rapid reconstitution of a bi-partite transcription factor in one partner to block re-fertilization and induce meiosis, thus ensuring genome maintenance during sexual reproduction.
Communicating corporate social responsibility (CSR) on social media
Authors: Wang Ruoxu , Huang Yan 
Published: May 2018

Purpose
The purpose of this paper is to examine the effects of message source and types of corporate social responsibility (CSR) message on stakeholder’s perception toward CSR and behavioral intention toward the company.

Design/methodology/approach
A 2 (message source: CEO’s Facebook account vs organization’s Facebook account) × 3 (types of CSR messages: internal CSR vs external CSR vs control) between-subjects online experiment (n=242) was conducted online.

Findings
Internal CSR message elicited greater perceptions of trust, satisfaction, control mutuality, and commitment toward the organization among the stakeholders than the external CSR message and the CEO’s personal life message. A significant two-way interaction between the message source and the type of CSR message on behavior intention toward the organization was obtained.

Originality/value
Internal CSR message does matter when it comes to social media posting. The general public do pay attention to what the CEO and the organizations are posting on their social media accounts. Message source does not matter when it comes to social media message posting. However, organizations and CEOs should try to stay consistent when it comes to creating a public CSR message.
What determines the presence of works councils in Polish companies?
Authors: Skorupińska-Cieślak Katarzyna 
Published: May 2018

PurposeThe purpose of this paper is to analyze the factors influencing the presence of works councils in Polish companies. The study also considers the incidence of councils in organizations and management’s attitude towards these institutions of employee participation.Design/methodology/approachBased on a sample of 402 Polish private companies, the probit model was calculated to identify the determinants of a works councils’ presence. The coverage of active councils was evaluated on the MRPiPS database and the GUS database.FindingsThe data show that the coverage of works councils in Polish organizations fell suddenly after the introduction of the amendment of the Act from 2009. Moreover, trade union density has a strong positive influence on the occurrence of works councils in companies. Councils are also more likely to be found in older foreign-owned companies in which forms of direct participation are used. Additionally, a higher share of shift workers in companies is associated with a higher probability of works councils’ presence.Research limitations/implicationsThere are some difficulties with obtaining a precise analysis of the coverage of works councils in Poland.Practical implicationsPolish findings may be useful for other countries of Central and Eastern Europe with similar characteristics of industrial relations and similarly short traditions of works councils.Originality/valueThis paper extends the previous research on the operation of works councils in Polish industrial relations by providing an econometric analysis of the determinants of councils’ presence in companies. Such an analysis has been conducted in Poland for the first time.
Personnel capability and customer satisfaction as predictors of customer retention in the banking sector
Authors: Darzi Mushtaq Ahmad , Bhat Suhail Ahmad 
Published: May 2018

PurposeThe purpose of this paper is to report the findings of a study undertaken to understand customer satisfaction and customer retention in business-to-consumer markets. The study investigates the effect of personnel capability and customer satisfaction on customer retention in the banking sector. The influence of the control variable (gender) on customer retention and mediating role of customer satisfaction has also been examined.Design/methodology/approachThe study has used structural equation modeling (SEM) for data analysis across a sample of 409 bank customers of a private bank operating in Jammu and Kashmir state of India. Questionnaires were distributed and respondents were selected through a cluster sampling technique.FindingsThe empirical analysis through SEM has confirmed that personnel capability and customer satisfaction have a significant positive impact on customer retention. Customer satisfaction partially mediates the effect of personnel capability on customer retention. Moderation analysis was performed and established that gender moderates the effect of personnel capability on customer satisfaction. It was also found that gender has no effect on other relations. Furthermore, the study shows that personnel capability has a stronger impact on customer retention as compared to customer satisfaction. However, the relationship between personnel capability and customer satisfaction is significant.Research limitations/implicationsThe study has been conducted on the customers of a private bank in India. Therefore, generalizations may be limited. As personnel capability is the predictor of satisfaction and retention, individuals with proper social and technical skills – in addition to other skills – should be hired for managing relationships with customers.Originality/valueThe study has added to the understanding of the relationship which exists among the following variables: gender, personnel capability, customer satisfaction and customer retention. These variables have not been studied together previously.
Predicting customer experience and discretionary behaviors of bank customers in India
Authors: Wasan Pratibha 
Published: May 2018

Purpose
Banks in India are underperforming on customer-centric measures. The existing mechanisms used by Indian banks for evaluating their customer interface are efficiency measures which are limited in deciphering bank’s success in fulfilling customer needs. The purpose of this paper is to build a case for banks to evaluate their processes on the dimension of customer experience (CE).

Design/methodology/approach
The study performs in-depth review of literature to identify the factors of CE and uses confirmatory factor analysis to confirm these factors in Indian retail banking context. Post factor confirmation, it uses discriminant analysis to test the predictive strength of the CE factors for discretionary behaviors of customers.

Findings
CE factors are categorized as functional clues (convenience and credibility), humanic clues (employee competence and compassion) and mechanic clues (service context). The study finds that the functional clues are the most significant predictors of customers’ discretionary behaviors followed by humanic clues while the mechanic clues are only hygiene factors for customer behaviors.

Practical implications
The study highlights CE factors which could be developed into potential competitive advantages for banks. Banks can prioritize their investments in these factors for improved economic performance.

Originality/value
There is no clear definition of CE in the extant literature particularly, in the context of retail banking. A factor-level study of CE for discretionary behaviors of bank customers is an attempt to provide specific inputs to those banks which are looking forward to use CE as a means to win and retain customers in markets characterized by intense competition.
Health investments and economic growth: a quantile regression approach
Authors: Rosendo Silva Francisca , Simões Marta , Sousa Andrade João 
Published: May 2018

Purpose
This study aims to analyse the relationship between health human capital and economic growth for a maximum sample of 92 countries over the period 1980-2010 taking into account countries’ heterogeneity by assessing how health variables affect different countries according to their position on the conditional growth distribution.

Design/methodology/approach
The paper estimates a growth regression applying the methodology proposed by Canay (2011) for regression by quantiles (Koenker, 1978, 2004, 2012a, 2012b) in a panel framework. Quantile regression analysis allows us to identify the growth determinants that present a non-linear relationship with growth and determine the policy implications specifically for underperforming versus over achieving countries in terms of output growth.

Findings
The authors’ findings indicate that better health is positively and robustly related to growth at all quantiles, but the quantitative importance of the respective coefficients differs across quantiles, in some cases, with the sign of the relationship greater for countries that recorded lower growth rates. These results apply to both positive (life expectancy) and negative (infant mortality rate, undernourishment) health status indicators.

Practical implications
Given the predominantly public nature of health funding, cuts in health expenditure should be carefully balanced even in times of public finances sustainability problems, particularly when growth slowdowns, as a decrease in the stock of health human capital could be particularly harmful for growth in under achievers. Additionally, the most effective interventions seem to be those affecting early childhood development that should receive from policymakers the necessary attention and resources.

Originality/value
This study contributes to the existing literature by answering the question of whether the growth effects of health human capital can differ in sign and/or magnitude depending on a country’s growth performance. The findings may help policymakers to design the most adequate growth promoting policies according to the behaviour of output growth.
Exploring the normative context for women’s entrepreneurship in Pakistan: a critical analysis
Authors: Roomi Muhammad Azam , Rehman Sumaira , Henry Colette 
Published: May 2018

Purpose
The role of women in Pakistani society – largely embedded in its patriarchal socio–cultural environment – has important implications for women’s entrepreneurial activity in the country. This study aims to investigate and analyse the influence of informal institutional factors on women’s entry into entrepreneurship in Pakistan, and determine how women exercise agency to cope with the constraints posed by such factors.

Design/methodology/approach
A qualitative approach is used to explore the normative context and lived experiences of women entrepreneurs in relation to the influence of socio–cultural beliefs and attitudes on their entrepreneurial career choices.

Findings
The findings suggest that women’s entrepreneurial career choices both revolve around and are shaped by a complex interplay of socio–cultural influences. Pakistani women entrepreneurs exercise their agency as a means of negotiating gender roles within both household and society, using religious descriptions as a means to justify their entrepreneurial activity.

Research limitations/implications
While every effort has been made to ensure that the data were objectively interpreted, and the derived findings were robustly analysed, the research team acknowledges the many difficulties associated with adopting a social constructionist approach. As articulated by Fletcher (2011), the key issues of contextual objectivity (i.e. where the researcher judges what is important), reflexive turn (the need for the researcher to constantly reconnect with the subject) and potential multiplicity of contexts (the various contextual and potentially conflicting influences on the researcher) presents ongoing challenges for researchers in this field.

Originality/value
This study offers valuable insights into the impact of the informal (socio–cultural) institutional factors on women’s entrepreneurial activity, opening up new avenues for further research. The study also contributes to the women’s entrepreneurship literature from the perspective of an Islamic developing country.
Buyers’ switching intentions in a manufacturing supply chain: a migration theory perspective
Authors: Suh Chang Juck , Kim Jong-Hoon 
Published: May 2018

PurposeThe purpose of this paper is to identify the negative impact of an incumbent supplier pushing out a buyer, the positive effect of an alternative supplier pulling a buyer, and the mooring impact that prevents a buyer from switching to a supplier in terms of the push-pull-mooring (PPM) model of migration theory. In this context, this study considers a buyer as the immigrant, an incumbent supplier as the origin, an alternative supplier as the destination, and inertia as the hesitance to migrate.Design/methodology/approachThis study collected survey data from 148 end-product manufacturers and first-tier suppliers. It tested whether the PPM model fit in a supply chain relationship (SCR) using the partial least squares structural equation modelling approach and SmartPLS package version 2.0.M3.FindingsThe results support all hypotheses for causal relationships among factors of cognitive, affect, and behavioural intentions of each PPM effect. This study identifies the relative importance of each effect on a buyer’s intention of switching an existing supplier.Originality/valueThis study presents a new perspective that enhances the understanding of a buyer’s behaviour towards a supplier by applying the PPM model of migration to a manufacturing SCR. It promotes interdisciplinary and integrated views as well as broadens the diversity of the results in the business-to-business context.
Enhancing librarianship students’ awareness of preservation at the learning resource center of a Mekong Delta university
Authors: Huynh Trang Thi , Lam Cuc Hong 
Published: May 2018

Purpose
This study aims to investigate the rate of print material deterioration at the Learning Resource Center – a university at the Mekong Delta and identify users’ behaviors that may harm library materials, thereby presenting some potential solutions to enhance librarianship students’ awareness of preservation.

Design/methodology/approach
The research is based on Walker’s (2003) conceptual framework of preservation and that of education and propaganda from awareness development. Using a quantitative approach, 25-item questionnaire was delivered to 133 sophomores and seniors and analyzed by SPSS software. Qualitative data from the open-ended question were recorded and analyzed by themes.

Findings
The findings from this study show that the rate of print material deterioration at the Learning Resource Center was relatively low compared to that of other libraries in the nation and in the world. In addition, students’ knowledge about how to make the photocopies, as well as how much to open the book, is limited. The most important reason is because of lack of education from school and the library. The research also proposed some effective and realizable solutions to enhance librarianship students’ awareness of preservation of the materials at Learning Resource Center of a Mekong Delta university, Vietnam.

Practical implications
This research provides library staff and users, especially librarianship students, with an awareness of the important role of book preservation, human behavior of library collections and potential preventive ways of book damage. This study also specifies evidence that library lecturers should include ethical issues in their lectures because librarianship students still have limited knowledge of book preservation. By doing so, these actions may motivate librarianship students to continue to learn and apply their knowledge of preservation into library materials and their own documents. Furthermore, the finding of the library work punishment contributes to better understanding of library labor force and students’ personality education. The findings can serve as a reference to educating other users in Vietnam and globally.

Originality/value
The level of print material deterioration at the Learning Resource Center of a Mekong Delta university, Vietnam and library work punishment were observed to be the most important findings with regard to library preservation in a particular library in Southeast Asian country. These findings provide insights into students’ awareness of preservation, not yet discussed in the literature.
Corporate governance and firm performance: an empirical evidence from Syria
Authors: Mardnly Zukaa , Mouselli Sulaiman , Abdulraouf Riad 
Published: May 2018

Purpose
This study aims to examine the impact of aggregate and individual corporate governance provisions on firm performance on all firms listed at Damascus Securities Exchange (DSE) for the period between 2011 and 2015. In addition, it disentangles ownership structure provision to ownership concentration and foreign ownership and investigates which component of ownership structure stands behind the significance of ownership structure in explaining firm performance.

Design/methodology/approach
The study uses multiple linear regression models to analyze the relationship between aggregate corporate governance index and its provisions and firm performance. A corporate governance index is built on the basis of four mechanics (i.e. board of directors, audit, disclosure and ownership structure) for all firms listed at DSE. On the other hand, the dependent variable (firm performance) is measured using Earnings Per Share (EPS) and Return On Assets (ROA). The authors capture current war conditions using political stability and absence of violence indicator, one of Worldwide Governance Indicators accumulated by the World bank.

Findings
This study finds that ownership structure is the only significant corporate governance provision in determining Syrian firms’ performance, as it loads positively and significantly on firm performance proxies (ROA and EPS). Moreover, the analysis of ownership structure items shows that foreign ownership is the main source of this positive and significant impact. This result is robust for both measures of firm performance and in the presence of political stability indicator.

Originality/value
This paper provides evidence on corporate governance measures from Syrian Arab Republic, a developing country with an emerging stock exchange. It examines board structure, ownership structure, audit committee and disclosure in a period of crisis because of the war in this country. Moreover, it uncovers that foreign ownership is the only influential provision affecting firm performance at DSE. Furthermore, it combines firm-level governance indicators with country governance indicator of political stability and absence of violence.
US unconventional monetary policy and Islamic equity indices
Authors: Ziaei Sayyed Mahdi 
Published: May 2018

Purpose
This paper aims to constitute to the first empirical work that investigated the effects of US unconventional monetary policy shocks on Islamic equities.

Design/methodology/approach
The authors used the spread between sovereign (term spread) and corporate (corporate spread) yields as proxies of unconventional monetary policy in times that FED implemented different rounds of large-scale asset purchasing programs.

Findings
This paper demonstrates that monetary policy shocks have significant effects on Islamic equities. The analysis showed substantial evidence that the corporate spread innovation was reflected as a positive signal in Islamic equity markets and has a larger impact on Islamic low leverage equities than term spread.

Originality/value
The objective of this paper is to shed some insight into the effects of US unconventional monetary policy on low leverage financial assets. It is hypothesized that during this period, specifically from November 2008, unconventional monetary policy and zero bound interest rates have been implemented in the US economy. However, the strength of effects of this range of policies on Islamic financial products is unidentified.