bluuebunny/crossref_metadata_2025_split huggingface dataset:
Utilization of Pleurotus eryngii biosorbent as an environmental bioremedy for the decontamination of trace cadmium(II) ions from water system
Authors: Amin Farah , Talpur Farah Naz , Balouch Aamna , Samoon Muhammad Kashif , Afridi Hassan Imran , Surhio Muhammad Ali 
Published: October 2018

Abstract
In many parts of the world, cadmium metal concentration in drinking water is higher than some international guideline values. To reduce its level below the safety limit, a sustainable and environmental friendly approach is crucial. Thereby, present article introduce an efficient, non-pathogenic and a novel fungal biosorbent Pleurotus eryngii for the removal of Cd(II) ions from aqueous system. The efficiency of P. eryngii were improved and optimized by investigating many significant factors such as; pH, biosorbent dose, initial Cd(II) ion concentration, temperature and contact time. Maximum Cd(II) ions removal (99.9%) was achieved at pH 5.0, biosorbent dosage 0.2 g/10 mL, concentration 20 mg L−1, time 10 min and temperature 50 °C. The isotherm and kinetic models revealed bioremediation of Cd(II) ions as monolayer coverage with biosorption capacity of 1.51 mg g−1 following pseudo second order reaction. Moreover, thermodynamic parameters such as ΔG°, ΔH°, and ΔS° showed that the removal of Cd(II) ions is spontaneous and endothermic in nature. Batch elution process revealed that the complete elution of Cd(II) ions from the biomass were achieved using 0.1 N HNO3 solution. The sorption efficiency decreased from 99.99 to 56.89% as the biomass were recycled up to five times. The efficiency of Cd(II) ions removal from real water samples lies between 85 and 90%. Fourier transform infrared (FTIR) spectrometry, scanning electron microscopy (SEM), energy dispersive X-ray spectroscopic (EDS) and atomic force microscopic (AFM) analysis of fungal biomass confirmed that the Cd(II) ions were the most abundant species on the biomass surface after the sorption process.
Generation of reactive oxygen species by promoting the Cu(II)/Cu(I) redox cycle with reducing agents in aerobic aqueous solution
Authors: Li Wenshu , Zhou Peng , Zhang Jing , Zhang Yongli , Zhang Gucheng , Liu Yang , Cheng Xin 
Published: October 2018

Abstract
This study investigated the generation of reactive oxygen species (ROS) (O2−•, H2O2, and HO•) by promoting the Cu(II)/Cu(I) redox cycle with certain reducing agents (RAs) in aerobic aqueous solution, and benzoic acid (BA) was employed as indicator for the hydroxyl radical (HO•). Hydroxylamine (HA) can reduce Cu(II) to Cu(I) to induce chain reactions of copper species resulting in the generation of the superoxide radical (O2−•) and hydrogen peroxide (H2O2), and the intermediate Cu(I) can further activate H2O2 via a Fenton-like reaction to produce HO•, creating the remarkable BA degradation. O2 is indispensable, and unprotonated HA is the motive power in the O2/Cu/HA system. Moreover, pH is a crucial factor of the O2/Cu/HA system due to the protonated HA not being able to reduce Cu(II) into Cu(I). The oxidation of HA can be effectively induced by trace amounts of Cu(II), and both a higher HA dosage and a higher Cu(II) dosage can enhance H2O2 generation and BA degradation. In addition, some other RAs that can reduce Cu(II) into Cu(I) could replace HA in the O2/Cu/HA system to induce the generation of these ROS in aerobic aqueous solution.
Automated monitoring system for events detection in sewer network by distribution temperature sensing data measurement
Authors: Kessili Abdelhak , Vollertsen Jes , Nielsen Asbjørn Haaning 
Published: October 2018

AbstractThis study is related to distribution temperature sensing (DTS) in sewers for tracing illicit or unintended inflows to foul sewers. A DTS measurement is performed with a fiber optic cable that is installed at the invert of a sewer pipe in combination with a standalone laser/computer instrument. This set-up generates in-sewer temperature measurements with high resolutions in time (every minute) and space (every metre) along the cable over long periods of time (weeks on end). The prolonged monitoring period in combination with the high level of detail in the dataset allows the study of anomalies (i.e., unexpected temperatures and/or temperature variations at certain locations), even if these only occur very infrequently. The objective of this paper is to develop an automated tool to analyze the large data masses and identify anomalies caused by illicit or unintended inflows. In this study, an algorithm for detecting the temperature changes that are caused by both wastewater discharge and inflow of stormwater are developed. A comparison of the results of the automated procedure to the results of a manual assessment of the datasets (Elmehaven, Denmark) shows that the automated procedure performs very well.
Поддержание нормотермии при интенсивной терапии тяжелой черепно-мозговой травмы
Authors: Tsarev A.V. 
Published: October 2018

Цель данного исследования — изучение эффективности контролируемой нормотермии в комплексе интенсивной терапии у пациентов с черепно-мозговой травмой (ЧМТ), осложненной развитием гипертермии центрального генеза, рефрактерной к фармакологической терапии, и оценка ее влияния на факторы, опосредованно определяющие реологические свойства крови. Материалы и методы. В исследование было включено 80 пациентов в возрасте от 20 до 64 лет (средний возраст 41,05 ± 2,90 года), находившихся на лечении в отделении интенсивной терапии с диагнозом «тяжелая черепно-мозговая травма», с развитием стойкой гипертермии > 38,3 °С, рефрактерной к фармакологической терапии антипиретиками. Пациенты были разделены на 2 группы: I (n = 40) — с проведением контролируемой нормотермии с целевым значением температуры тела 37 °С при помощи гипотерма Blanketrol II; II группа (n = 40) — пациенты с гипертермией > 38,3 °С изучались ретроспективно, лечение гипертермии у них включало обкладывание тела пакетами со льдом в проекциях прохождения магистральных сосудов. Результаты. Было выявлено достоверное увеличение уровня фибриногена на этапе развития гипертермии в I группе пациентов с 2,92 ± 0,64 до 5,24 ± 1,37 г/л (Р = 0,00001), во II группе — с 2,99 ± 0,67 до 5,32 ± 2,06 г/л (Р = 0,00006) по сравнению с исходным уровнем. У пациентов I группы при проведении контролируемой нормо­термии выявлено снижение уровня фибриногена, который на этапе 48 часов достоверно не отличался от исходного уровня (Р = 0,47). Напротив, у пациентов II группы на всех этапах отмечалось повышение уровня фибриногена, и на этапе 48 часов увеличение данного показателя по сравнению с исходным уровнем носило достоверный характер (Р = 0,00015). Различия по уровню фибриногена на этапе 48 часов наблюдения между группами пациентов также были достоверными (p < 0,05). Выводы. Контролируемая нормотермия нормализует уровень фибриногена до исходных значений, что опосредованно может свидетельствовать об улучшении реологических свойств крови и, соответственно, системной микроциркуляции при тяжелой ЧМТ.
Зміни ендокринної функції тимуса, макрофагів і Т-лімфоцитів головного мозку в мишей різного віку після введення нейротоксину купризону і цитокіну
Authors: Labunets I.F. 
Published: October 2018

Актуальність. Відома участь макрофагів і Т­лімфоцитів в ушкодженні нервових клітин головного мозку. Гормон тимуса тимулін виявляє імуномодулюючі й антизапальні властивості. Вікові зміни активності макрофагів, Т­лімфоцитів головного мозку та тимуса можуть впливати на їх відповідь на дію токсичних та регуляторних факторів. Мета — дослідження змін рівня в крові тимуліну та кількості макрофагів і Т­лімфоцитів у головному мозку молодих і старіючих мишей, яким вводили нейротоксин купризон і рекомбінантний лейкемія­інгібіторний фактор людини (rhLIF). Матеріали та методи. Миші лінії 129/Sv отримували з їжею щоденно купризон упродовж 3 тижнів. З 8­ї доби купризонової дієти щоденно вводили rhLIF у дозі 50 мг/кг. Результати. Підвищення рівня в крові тимуліну через 7 діб прийому купризону інтенсивніше в молодих мишей, ніж у старіючих. Через 3 тижні купризонової дієти рівень гормона зменшувався тільки в молодих мишей. Кількість макрофагів у головному мозку молодих мишей збільшувалась вже через 7 діб прийому купризону, а у старіючих — тільки через 3 тижні. У мишей обох вікових груп із купризоновою дієтою (особливо в молодих) збільшувалась кількість Т­клітин у головному мозку. Ін’єкції rhLIF підвищували рівень у крові тимуліну і зменшували кількість Т­клітин у головному мозку молодих мишей, тоді як у старіючих мишей спостерігалось зменшення кількості макрофагів у головному мозку. Висновки. Дія як купризону, так і rhLIF на ендокринну функцію тимуса та кількість макрофагів і Т­лімфоцитів у головному мозку мишей залежить від віку.
Метод радіочастотної нейроабляції в лікуванні больового синдрому крижово-клубового суглоба
Authors: Fishchenko Ya.V. , Kudrin A.P. , Kravchuk L.D. 
Published: October 2018

Актуальність. У формуванні больових синдромів попереково-крижової локалізації провідну роль відіграє дисфункція крижово-клубового зчленування. Радіочастотна нейроабляція крижово-клубового суглоба (ККС) може бути альтернативним методом лікування больового синдрому при неефективності внутрішньосуглобових ін’єкцій гормональних препаратів. Множинні дослідження підтверджують дані про значну ефективність радіочастотної нейроабляції нервів, що іннервують ККС, терміном на 6–12 міс. Мета дослідження: провести аналіз ефективності застосування радіочастотної нейроабляції крижово-клубових суглобів. Матеріали та методи. Проаналізовані дані 48 пацієнтів (12 чоловіків і 36 жінок) віком від 53 до 90 років, які пройшли амбулаторне лікування у відділенні реабілітації ДУ «Інститут травматології та ортопедії НАМН України». Результати. Було встановлено зниження больового синдрому за візуально-аналоговою шкалою (регресування болю на 3–10 балів) через 12 міс. у 83 % пацієнтів. За результатами оцінки якості життя (анкетування з використанням анкети Роланда-Морріса) через 12 міс. вірогідне поліпшення спостерігалося у 77,16 % пацієнтів. Аналізуючи результати лікування (за індексом одужання) через 12 міс. встановлено: відмінний результат — у 38 %, добрий — у 42 % пацієнтів, задовільний — у 20 % (серед них погіршення порівняно з вихідним станом відзначали 8,3 % пацієнтів). Висновки. Радіочастотна нейроабляція — ефективний метод лікування больового синдрому крижово-клубового суглоба. Ефект від процедури довготривалий (більше 12 міс.), при рецидиві больового синдрому можливе проведення повторних процедур.
Building Condition Assessments – Methods and Metrics
Authors: Mayo Glenda , Karanja Pauline 
Published: October 2018

ABSTRACTThe aim of the research included an exploration of the condition assessment process, and the Facilities Condition Index (FCI) as a metric to assign condition levels for commercial structures. The computation and use of various metrics for the asset management process are not standardized. The paper aims to clarify the current industry practices regarding how various assessments are currently utilized and to also compare existing literature to existing industry practices. Utilizing the Delphi Technique, an industry panel provided a synopsis of current practices. The research included organized discussions with industry as a method to supplement the Delphi survey responses and ensure accurate representation of industry practices. The assessment of the current standard of practice revealed that there is currently no established assessment methodology for data collection and the lack of proper categorization of the assets within a building hampers the frequent and widespread use of specific performance metrics within the industry. Although the intent was to establish consensus, the results of this study provide a clear indication that the disagreement levels in the categories represent the overall industry struggles, the lack of standards, and issues in the use of metrics, especially with the varied computation of the FCI. Existing literature is limited in the areas of condition metrics, especially for applied recommendations. The results provide a foundational state of practice and highlight the needed industry improvements for condition assessments and additionally, how FM's utilize the data they collect.
PENGENDALIAN PENYAKIT BLAS (Pyricularia oryzae) PADA BEBERAPA VARIETAS PADI GOGO MENGGUNAKAN MIKORIZA INDIGENOUS DAN NON INDIGENOUS
Authors: Suriani Suriani , Fikrinda Fikrinda , Marlina Marlina 
Published: October 2018

Suatu untuk pengendalian penyakit blas pada padi gog telah dilaksanakan di dalam Rumah Kasa Kebun Percobaan, Laboratorium Hama dan Penyakit Tanaman, dan Laboratorium Biologi Tanah Fakultas Pertanian Universitas Syiah Kuala, Band Aceh. Pelaksanaan penelitian dimulai pada bulan November 2017 sampai Februari 2018. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) pola faktorial yang terdiri atas 2 faktor dengan ulangan sebanyak 3 kali. Faktor pertama yaitu perlakuan mikoriza yang terdiri atas M1: Mikoriza Indigenous, M2: Mikoriza non Indigenous. Sedangkan faktor kedua yaitu varietas/padi gogo yang terdiri atas : varietas Situ Patenggang (V1), galur Unsyiah 01 Simeulu (V2), galur Unsyiah 05 Sibahak (V3), dan galur Unsyiah 07 Sibabus (V4).
Hasil penelitian menunjukkan bahwa mikoriza indigenous dan non indigenous tidak berpengaruh terhadap masa inkubasi dan persentase tanaman terserang penyakit blas pada varietas padi Situ Patenggang dan galur Unsyiah 01 Simeulu, Unsyiah 05 Sibahak, dan Unsyiah 07 Sibabus. 2). Mikoriza indigenous dapat menekan keparahan penyakit blas pada varietas Situ Patenggang dan galur Unsyiah 07 Sibabus. Sedang mikoriza non indigenous dapat menekan keparahan penyakit pada galur Unsyiah 01 Simeulu dan galur Unsyiah 05 Sibahak.
Pharmacological Evaluation of the Effects of Phenylcarbamic Acid Derivatives on Cardiovascular Functions in Rats
Authors: Kralova Eva , Racanska Eva , Vicenova Anna , Boselova Iveta , Malik Ivan , Stankovicova Tatiana 
Published: October 2018

Abstract
Four phenylcarbamic acid derivatives, (1-(4-fluorophenyl)- 4-[3-(4-methoxyphenylcarbamoyloxy)-2-hydroxypropyl]piperazinium chloride (1), (1-(2-methylphenyl)-4-[3-(4-methoxyphenylcarbamoyloxy)- 2-hydroxypropyl]piperazinium chloride) (2), (1-(2-methylphenyl)-4-[3-(4-ethoxyphenylcarbamoyloxy)- 2-hydroxypropyl]piperazinium chloride) (3) and (1-(3-trifluoromethylphenyl)-4-[3-(4-methoxyphenylcarbamoyloxy)- 2-hydroxypropyl]piperazinium chloride) (4) were investigated for their ability to affect various cardiovascular functions and to establish their chemical structure-biological activity relationship. The compounds were evaluated for their antiarrhythmic efficacy using ouabain-induced rhythm disturbances and the ability to inhibit the positive chronotropic effect of isoproterenol in isolated atria of Wistar rats. Electrocardiogram (ECG) parameters in isolated hearts of spontaneously hypertensive rats (SHR) perfused according to the Langendorff method and ability to decrease phenylephrine- -induced contraction of the aortic strips after repeated administration of the compounds were also analyzed. Only compound 3 delayed significantly the evaluated parameter of arrhythmogenicity and was able to antagonize the isoproterenol- induced positive chronotropic effect in normotensive rats’ atria. Similarly, in SHR rats, only compound 3 was able to decrease heart frequency significantly without influencing the duration of QT (time between the start of the Q wave and the end of the T wave) and QTc (frequency corrected QT) intervals. The evaluated endothelial function was improved after administration of compound 2. Fluorine-containing structures (1 and 4) were less effective compared to 2´-methylphenylpiperazine derivatives (2 and 3). The latter two compounds showed suitable efficacy, which supported their use for futher pharmacological research.
Immunomodulatory Effects of Tigecycline in Balb/C Mice
Authors: Elhayek Shada Y. , Fararjeh Mohammad A. , Assaf Areej M. , Abu-Rish Eman Y. , Bustanji Yasser 
Published: October 2018

Abstract
Tigecycline is a glycylcycline antibiotic approved by the FDA for the treatment of complicated infections. Despite its effectiveness, the FDA announced a warning of increasing mortality associated with its use. There is, however, no clear explanation for this side effect. Previous reports found a possible effect of tigecycline on leukocyte proliferation and proinflammatory cytokine release. We t herefore i nvestigated the effect of tigecycline on the immune components and response in Balb/c mice in vivo and in vitro. It was found that tigecycline enhanced lymphocyte proliferation and significantly increased cellular infiltration within the footpad, as based on DTH testing, but reduced the hemagglutination titer. In splenocyte cultures, tigecycline suppressed splenocyte proliferation with IC50 3-5 mmol L-1, significantly increased IL-2 secretion and reduced IL-17 secretion in a dose dependent mode. In conclusion, tigecycline is safe at therapeutic and sub-therapeutic doses, but it could still have an immunomodulatory effect at higher doses. Use of higher doses of tigecycline requires further investigation.
Simulation of the Transmission by Vectors of Bluetongue Disease and Analysis of the Control Strategy
Authors: Đurić Spomenka , Mirilović Milorad , Magaš Vladimir , Bacić Dragan , Stanimirović Zoran , Stanojević Slobodan , Stanojević Slavoljub 
Published: October 2018

Abstract
Bluetongue disease is an infectious non-contagious disease of domestic and wild ruminants, transmitted by hematophagous insects of the genus Culicoides. In endemic areas the disease has a seasonal character, occurs usually in summer when the population of vectors is at its peak. Culicoides are active at temperatures in the range from 13oto 35oC. The replication of the virus stops when the environmental temperature is below 13oC. It has been reported that the temperature and humidity of the environment affect to a great extent the biology of the vector and the survival of the virus in the reservoirs. During the summer, the number of infected cattle and sheep is directly dependent on the density of the population of the vector, the length of vectors’ life-span, the temperature of the environment and by precipitation, the affi nity of the vector to different hosts, and the ability of the vector to locate the host. Bluetongue has been spreading worldwide due to climatic changes and increasing average daily temperatures. The seasonal occurrences of the disease and the climate change have conditioned the need for adopting new strategies. The stochastic SEIRD mathematical model has been developed in order to simulate the transmission of the Bluetongue virus through the susceptible ruminant population on the territory of the Republic of Serbia, as well as to investigate the effect of climatic factors on the vector population and the magnitude of a possible epizootia. Besides the effects of climatic factors, we have analyzed a number of different approaches in the control of the disease based upon the vaccination of ruminants and control of vectors.
Relationships between Thoroughbreds’ Contribution in the Pedigree and the Level of Fearfulness and Performance in Warmblood Stallions
Authors: Monika Budzyńska , Jarosław Kamieniak , Beata Marciniak , Leszek Sołtys 
Published: October 2018

Abstract
The aim of this study was to test the hypothesis that Thoroughbred (TB) ancestors blood percentage in a pedigree is a potential factor differentiating the level of fearfulness (based on behavior and heart rate (HR)) and performance scores in warmblood stallions. A total of 267 three-year-old warmblood stallions were subjected to the novel-object based test during their participation in the performance tests’ program. The effect of ancestors percentage contribution in the pedigree was analyzed by taking into account horses of four TB (<25.01, 25.01-50.00, 50.01-75.00, >75.00%) ancestor groups. It was found that the stallions with a higher proportion (>75.00%) of TB blood revealed higher values of HR measured at the riding hall just before the start of the fearfulness test. The results showed that the higher proportions of TB ancestors blood in the stallions’ pedigree were correlated with the higher values for total time to pass novel objects when led by a handler during the fearfulness test. Negative correlations were found between the TB percentage and the scores for character and trot evaluated by the trainer as well as rideability evaluated by the test rider. The fi ndings imply that a high proportion of Thoroughbreds in the pedigree may negatively infl uence some performance traits and increase fear reactivity in warmblood stallions.
Clara cell protein 16 release from the nasal mucosa in allergic rhinitis, chronic rhinosinusitis, and exposure to air pollutants
Authors: Perić Aleksandar , Mirković Cveta Špadijer , Vojvodić Danilo 
Published: October 2018

Abstract
Clara cell protein 16 (CC16) is a small protein mainly produced by non-ciliated Clara cells in the respiratory epithelium. It has an anti-inflammatory role in chronic upper and lower airway eosinophilic inflammations. Decreased levels of CC16 are found in the nasal secretions and plasma of patients with chronic eosinophilic inflammatory disorders, such as asthma, allergic rhinitis, and chronic rhinosinusitis with or without nasal polyps, as well as in people exposed to high levels of air pollutants. Intranasal corticosteroid administration suppresses chronic inflammation of the nasal mucosa driven by eosinophils and stimulates local CC16 production. CC16 can be a reliable biomarker of the beneficial effects of perennial allergic rhinitis and chronic rhinosinusitis therapy and of the functional recovery of the nasal mucosa after treatment with topical glucocorticoids.
Occupational exposure to bioburden in Portuguese bakeries: an approach to sampling viable microbial load
Authors: Viegas Carla , Monteiro Ana , Carolino Elisabete , Viegas Susana 
Published: October 2018

Abstract
In bakeries, a number of operations such as mixing are associated with exposure to air-suspended flour dust and related bioburden. The aim of this study was to find the best active sampling approach to the assessment of occupational exposure to bioburden in Portuguese bakeries based on the data obtained with the use of specific impaction and impinger devices. We used impaction to collect fungal particles from 100 L air samples onto malt extract agar (MEA) supplemented with chloramphenicol (0.05 %). For growing fungi we also used dichloran glycerol (DG18) agar-based media and for mesophilic bacteria we used tryptic soy agar (TSA) supplemented with nystatin (0.2 %). For Enterobacteriaceae we used violet red bile agar (VRBA). With impingers we also collected 300 L air samples at the 300 L/min airflow rate, inoculated onto the same culture media. The two methods, impaction and impinger, showed statistically significant differences in the following counts: fungal on MEA (z=-2.721, p=0.007), fungal on DG18 (z=-4.830, p=0.000), total bacteria (z=-5.435, p=0.000), and Gram-negative coliforms (z=-3.716, p=0.000). In all cases the impaction method detected significantly higher concentrations than the impinger method. Fungal and bacterial loads were higher in the production unit and lower in the shop. The fungal load obtained with impaction varied between 10 and 5140 CFU m-3, and total bacterial counts ranged between 10 and 4120 CFU m-3. This study has shown that the impaction method is the best active sampling approach to assessing viable bioburden in this specific occupational environment, but a multi-faceted approach to sampling and analyses combining methods and media enables a more refined risk characterisation and, consequently, better tailored risk control measures to reduce adverse health outcomes in workers.