bluuebunny/crossref_metadata_2025_split huggingface dataset:
Viability of Human Periodontal Ligament Fibroblasts in Tissue Culture After Exposure to Different Contact Lens Solutions
Authors: Al-Nazhan Saad , Al-Nasser Afaf 
Published: July 2019

Abstract

Aim
The viability of the periodontal ligament (PDL) cells is critical for successful healing of replanted avulsed teeth. Viability is primarily dependent on the duration of the extra-alveolar time and storage medium used to preserve teeth. Several storage media have been suggested but milk ranks highest. It would be desirable to evaluate other media as a suitable alternative for milk. The purpose of this study was to determine the viability of human PDL fibroblasts and their morphology after storage in different types of contact lens solutions.

Methods and Materials
PDL fibroblasts were cultured from a healthy extracted impacted human tooth and exposed to Bausch and Lomb (Renu), Ciba Vision (Titmus), and Alcon (Opti-free) contact lens solutions. Eagle's minimal essential medium served as control. The experiment was performed in plastic tissue culture clusters containing 24 wells. The PDL fibroblasts were grown in each well for three days. On the day of the experiment the culture medium was decanted, the cells were washed with phosphate buffered saline solution (PBS), and 1 ml of the tested solution was placed in each culture well. All tissue culture clusters were incubated at 37°C in 5% CO2 and 95% air for one, four, and 24 hrs. At the end of the incubation period, the cells were fixed and prepared for scanning electron microscope (SEM) examination.

Results
The results indicated Renu and Opti-free solutions were superior to Titmus solution in terms of their capacity to maintain the viability and normal morphology of PDL fibroblasts.

Conclusion
Contact lens solution is a good storage medium to maintain the viability of PDL fibroblasts for a short-term period.

Citation
Al-Nazhan S, Al-Nasser A. Viability of Human Periodontal Ligament Fibroblasts in Tissue Culture After Exposure to Different Contact Lens Solutions. J Contemp Dent Pract 2006 September;(7)4:037-044.
Effects of Repeated Fluoride Varnish Application on Different Restorative Surfaces
Authors: Salama Fouad S. , Schulte K. Marche' , Iseman Michael F. , Reinhardt John W. 
Published: July 2019

Abstract

Aim
The aim of this study was to assess the effect of repeated (twice) applications of two fluoride varnishes (Duraflor and CavityShield) on the surface micromorphology of a high-viscosity glass ionomer (Fuji IX GP), a compomer (F2000), and a flowable composite (Filtek™ Flow) using a profilometer and scanning electron microscope (SEM).

Methods and Materials
Fifteen specimens were prepared from each material, surface roughness (Ra) was measured with a profilometer, and an impression was made for epoxy replicas. The fluoride varnishes were applied to the experimental specimens of each material at repeated intervals of 48 hours. For all specimens, Ra was measured and SEM replicas were examined.

Results
The final Ra of glass ionomer was 3.49 ± 0.59 (mean ± SD) for CavityShield, 4.69 ± 1.33 for Duraflor, and 2.96 ± 1.53 for the controls. The final Ra of flowable composite was 0.53 ± 0.20 for CavityShield, 2.61 ± 3.08 for Duraflor, and 0.15 ± 0.09 for controls. For glass ionomer and flowable composite, Duraflor was associated with a significantly higher roughness at the final measurement compared to controls (P < 0.05). SEM micrographs showed differing surface topographies which in many specimens confirmed Ra analysis.

Conclusion
Fuji IX GP and Filtek™ Flow showed significantly higher roughness after two applications of Duraflor compared to controls.

Citation
Salama FS, Schulte KM, Iseman MF, Reinhardt JW. Effects of Repeated Fluoride Varnish Application on Different Restorative Surfaces. J Contemp Dent Pract 2006 November;(7)5:054-061.
Prevalence and Severity of Hypertension in a Dental Hygiene Clinic
Authors: Hughes Cynthia T. , Collins Marie A. , Thompson Ana Luz , Downey Mary Cannon , Herman Wayne W. , LNU Joseph Louis Konzelman , Ward Sue Tucker 
Published: July 2019

Abstract

Aim
The purpose of this study was to assess the prevalence and severity of hypertension in a dental hygiene clinic and evaluate factors related to the disease.

Methods and Materials
Records of 615 patients, treated by dental hygiene students during 2003, were reviewed. Data collected included systolic and diastolic blood pressure, presence of diabetes and renal disease, non-modifiers (race, gender, and age), and modifiers (marital status, smoking habits, and occupation).

Results
According to the Seventh Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (JNC7) classification, 154 (25%) of the subjects had normal blood pressure readings, 374 (60.8%) had prehypertension, and 87 (14.1%) had stage 1 hypertension. Statistical analysis showed a significant difference in the JNC7 classification between groups when considering the non-modifiers’ race (p=.02) and the modifiers’ smoking habits (p=.03) and occupation (p=.01). A statistically significant difference in the JNC7 classification existed between groups with diabetes (p=.00). The majority of patients had blood pressure readings in the prehypertension stage.

Conclusion
Based on these results, the researchers recommend clinical policy modifications which include: additional documentation for blood pressure readings in the prehypertension stage, lowering the systolic reading from 160 mmHg to 140 mmHg when adding hypertension alert labels, and noting prehypertension/ hypertension on the dental hygiene care plan with the appropriate interventions.

Citation
Thompson AL, Collins MA, Downey MC, Herman WW, Konzelman Jr JL, Ward ST, Hughes CT. Prevalence and Severity of Hypertension in a Dental Hygiene Clinic. J Contemp Dent Pract 2007 March;(8)3:013-020.
Orthodontic Treatment Complexity and Need in a Group of Nigerian Patients: The Relationship between the Dental Aesthetic Index (DAI) and the Index of Complexity
Authors: Onyeaso Chukwudi Ochi 
Published: July 2019

AbstractAimThe aim of this retrospective analytical study was to assess the relationship between the Dental Aesthetic Index (DAI) and the Index of Complexity, Outcome, and Need (ICON) on the orthodontic treatment need and complexity in a group of Nigerian patients.Methods and MaterialsFifty-six cases were randomly selected from the model storage of the orthodontic unit of the University College Hospital in Ibadan, Nigeria. The ICON was used to assess the pre-treatment study models for orthodontic treatment need and complexity of the cases while the DAI was also used to assess the same cases for treatment need. Descriptive statistics as well as the non-parametric (Spearman Rank-Order and Pearson's Product Moment) correlations were used to analyze the data.ResultsThe mean ICON and DAI scores were 67.38±19.63 (SD) and 42.27±12 .66 (SD), respectively. Both the ICON and DAI agreed that one (1.8%) case did not need treatment while 46 (82.1%) needed treatment. All the difficult and very difficult cases according to the ICON were assessed as needing treatment by the DAI with 18 (13.1%) out of 22 (39.3%) in the very difficult category belonging to the handicapping group where treatment was mandatory. In all positive significant correlations were recorded for the ICON and DAI scores.ConclusionThe ICON and DAI showed favorable agreement when used to assess treatment needs through the use of study casts. The ICON could be a good substitute for the DAI in assessing pre-treatment needs of Nigerian patients.CitationOnyeaso CO. Orthodontic Treatment Complexity and Need in a Group of Nigerian Patients: The Relationship between the Dental Aesthetic Index (DAI) and the Index of Complexity, Outcome, and Need (ICON). J Contemp Dent Pract 2007 March;(8)3:037-044.
Non-syndrome Multiple Supernumerary Teeth: A Case Report
Authors: Gündüz Kaan , Muğlali Mehtap 
Published: July 2019

Abstract

Aim
The purpose of this case report is to present a case of a non-syndrome male patient with multiple supplemental supernumerary teeth in three quadrants of his mouth.

Background
Supernumerary teeth are described as the teeth formed in excess of the number found in a normal dentition. Prevalence of supernumerary teeth varies between 0.1% and 3.8% in the general Caucasian population. Multiple supernumerary teeth are not a common occurence, although a single or a few supernumerary tooth/teeth in each case have been widely reported in the literature.

Report
An 11-year-old male presented for a routine preventive dental visit. A routine panoramic radiograph showed the presence of multiple supernumerary teeth which were located in the maxillary right canine incisor region, the maxillary left premolar region, and the mandibular right premolar region. The family's medical history was non-contributory, and an extraoral examination did not reveal any abnormality.

Summary
It is rare to find multiple supernumerary teeth in individuals with no other associated diseases or syndromes. This case report presents a case of a non-syndrome male patient with multiple supplemental supernumerary teeth in three quadrants of his mouth.

Citation
Gündüz K, Muğlali M. Non-syndrome Multiple Supernumerary Teeth: A Case Report. J Contemp Dent Pract 2007 May;(8)4:081-087.
Periodontal Findings and Blood Analysis of Blood Donors: A Pilot Study
Authors: Hornecker Else , Ziebolz Dirk , Jäger Gesa C. , Mausberg Rainer F. 
Published: July 2019

Abstract

Aim
Before blood donation a medical check-up is mandatory to ascertain the health of the donor and to detect infections clinically. Although gingivitis and periodontitis are also bacterial infections, the oral cavity is only inspected superficially. The purpose of this study was to investigate the periodontal condition of blood donors and whether this affects the results of their blood tests.

Methods and Materials
A total of 192 blood donors were examined. The investigation included a periodontal examination to determine the Community Periodontal Index (CPI), an analysis of blood chemistry, as well as the determination of hematologic, coagulation, and immune parameters C-reactive protein (CRP), Neopterin, Procalcitonin (PCT), and tumor necrosis factor (TNF-α). Groups were formed according to periodontal status: “healthy” (n=47, mean age 24±4 years), “gingivitis” (n=65, mean age 24±4 years), and “periodontitis” (n=80, mean age 29±8 years). Most parameters of the routine blood test as well as the immune parameters were unremarkable with regard to the periodontal status. The values for SGPT, GGTP, uric acid, triglycerides, total protein (TP), RBC, hemoglobin (Hb) and hematocrit (HC), Eos, and Baso were also within the normal range. Nevertheless, statistical analysis showed some significant differences in these parameters between the “healthy” group and the “periodontitis” group (p≤0.05).

Results
The results of this study show some blood donors have infections of the gingiva and/or of other periodontal tissues. Whether this is a sufficient reason to exclude them from blood donation, or in which case potential donors should be excluded, is not yet known. Nevertheless, it seems reasonable to integrate a screening method for revealing at least severe periodontitis in the medical check-up of blood donors.

Citation
Ziebolz D, Jäger GC, Hornecker E, Mausberg RF. Periodontal Findings and Blood Analysis of Blood Donors: A Pilot Study. J Contemp Dent Pract 2007 July;(8)5:043-050.
Oral Paracoccidioidomycosis: A Case without Lung Manifestations
Authors: Andrade Miguel Gustavo Setúbal , Medrado Alena Peixoto , de Brito Igor Costa , de Almeida Reis Silvia Regina 
Published: July 2019

Abstract

Aim
The aim of this article is to present a case of Paracoccidioidomycosis with involvement of the oral cavity but without pulmonary manifestations.

Background
Paracoccidioidomycosis is a fungal infection caused by Paracoccidioides brasiliensis. It is an endemic disease representing a serious health problem for Latin American countries, especially Brazil. This infection primarily affects the lungs of adult men and is acquired through inhalation or accidental inoculation of the fungus. It can spread to other organs and tissues, mainly the oral cavity. Administration of antifungal medication always resolves the disease.

Report
A 58-year-old black male presented with three painless, ulcerated, mulberry-like granulomatous lesions located in the floor of the mouth, on the superior alveolar ridge, and on the hard palate, which had evolved over a period of two years. Facial asymmetry was observed due to edema in the lower lip and lymphadenopathy. He had smoked for more than six years but showed no evidence of lung alterations, productive cough, or fever. Panoramic radiography showed no signs of a bone lesion in the jaws. Both a radiograph and a CT scan of the thorax showed no areas of nodular infiltration. Fibrobronchoscopic examination of the entire respiratory tract was normal. Biopsies of the oral lesions were performed, and tissue sections exhibited oral mucosa coated with non-keratinized stratified squamous epithelium with acanthosis and focal areas of exocytosis. The underlying connective tissue showed an intense lymphocytic and polymorphonuclear infiltrate in addition to multinuclear giant cells and coagulation necrosis. A special stain used for fungus (the Grocott-Gomori method) was positive. Pulmonary biopsy exhibited aerial spaces containing macrophages, dark granular hemossiderin, and absence of fungus. This was considered normal. In agreement with the recommendation of pneumologists 400 mg/day of ketoconazole was prescribed for the patient. After two months of treatment, even though the oral lesions had resolved completely, the therapy was maintained for six months more. One year after following treatment the patient was in good health and free of any signs of a recurrent infection.

Summary
Based on clinical, radiographic, and histologic findings the differential diagnosis included paracoccidioidomycosis and squamous cell carcinoma. Following clinical and biopsy examinations of the oral lesions and the lungs a final diagnosis of paracoccidioidomycosis was made. This is a prime example of oral manifestations of a systemic disease in which the dentist is the initial health care professional to evaluate the patient due to the location of the lesions.

Citation
Andrade MGS, Medrado AP, de Brito IC, de Almeida Reis SR. Oral Paracoccidioidomycosis: A Case without Lung Manifestations. J Contemp Dent Pract 2007 July;(8)5:092-098.
Anticaries Potential of Commercial Dentifrices as Determined by Fluoridation and Remineralization Efficiency
Authors: Casals Elias , Boukpessi Tchilalo , McQueen Christina M. , Eversole Sandy L. , Faller Robert V. 
Published: July 2019

Abstract

Aim
The aim of this in vitro study was to investigate fluoride uptake in human enamel after use of commercially available toothpastes containing different fluoride compounds, or combinations of fluoride actives formulated into a single product, as a means of determining the efficiency of each formula for delivering caries preventing fluoride to demineralized (caries active) enamel.

Methods and Materials
Four test dentifrices and two controls were assessed and placed in groups as follows: Group 1: Lacer® (Spain); Group 2: Positive control-USP Reference Standard 1100 ppm F; Group 3: Fluocaril® Bi-Fluoré 250 (France); Group 4: Colgate Fluor Active (Denmark); Group 5: Elmex® (France); and Group 6: A placebo (formulated the same as the USP Reference Standard toothpaste with the exception that it contained < 1 ppm F). Cores 3 mm in diameter were removed from erupted human enamel specimens (extracted by local oral surgeons for orthodontic reasons) and stored in 1% Thymol solution prior to use. They were ground and polished to remove the natural fluoride rich enamel layer, then exposed to a demineralization solution, and assessed for surface microhardness to enable randomization for use in the study. Each group of five specimens underwent a daily pH cycling procedure that involved exposure to pooled human saliva (refreshed three times daily). The groups were then exposed to dentifrice slurries four times daily for one minute per exposure and to a demineralization solution for three hours. The cycling procedure was repeated for five days. Specimens were again analyzed for surface microhardness and fluoride uptake upon completion of five days of treatment.

Results
Average surface hardness: Groups 2 and 3 showed a statistically significant greater (p<0.05) change indicating greater remineralization compared to all other groups. The average change was 23.45 for Group 2 and 22.65 for Group 3. All other groups had changes ranging from 4.25-8.62. No other statistically significant differences were observed between groups. Fluoride uptake results: Groups 2 and 3 showed statistically significantly greater fluoride uptake versus all other groups (p <0.05). Groups 1 and 5 were significantly different from Group 6. No other statistically significant differences were observed for either analysis.

Conclusions
Of the marketed products included in the study, the Fluocaril® Bi-Fluoré 250 product formulation provided both the highest level of fluoride uptake and mineralization to the demineralized enamel. The clinical significance of these in vitro results is the confirmation Fluocaril® Bi-Fluoré 250 is effective at remineralizing enamel caries lesions.

Citation
Casals E, Boukpessi T, McQueen CM, Eversole SL, Faller RV. Anticaries Potential of Commercial Dentifrices as Determined by Fluoridation and Remineralization Efficiency. J Contemp Dent Pract 2007 November; (8)7:001-010.
Prosthetic Rehabilitation of a Complete Bilateral Maxillectomy Patient Using a Simple Magnetically Connected Hollow Obturator: A Case Report
Authors: Chandra T. Sunil , Sholapurkar Amar , Joseph Robin Mathai , Aparna I.N. , Pai Keerthilatha M. 
Published: July 2019

Abstract

Aim
The purpose of this clinical report is to present a description of the prosthetic rehabilitation of a bilateral complete maxillectomy patient using a two piece magnetically connected prosthesis.

Background
A complete bilateral maxillectomy defect presents a considerable reconstructive challenge for the prosthodontist. It results in devastating effects on cosmetic, functional, and psychological aspects of the patient.

Report
A 46-year-old woman reported with a chief complaint of missing teeth in the upper jaw. Her primary concerns were a poor facial appearance, inability to chew food, and regurgitation of the food into the nasal cavity. She was diagnosed with carcinoma of the maxillary sinus, for which a bilateral maxillectomy was done followed by post surgical radiation therapy. The prosthetic treatment objectives were to separate the nasal and oral cavities, restore the mid-facial contour, and improve her masticatory functions by providing a full complement of maxillary teeth using a two-piece connected hollow obturator prosthesis connected by a magnet.

Summary
Insertion and removal of a large prostheses used for rehabilitation of midfacial defects requires good neuromotor coordination and an adequate mouth opening. Because these factors were problematic for this patient, the treatment plan was to fabricate a two piece magnetically connected prosthesis. After fabrication and insertion of the prosthesis, the fit between two sections was evaluated and instructions for insertion, removal, and maintenance of the obturator were given. The patient's speech, masticatory efficiency, and swallowing dramatically improved after insertion.

Citation
Chandra TS, Sholapurkar A, Joseph RM, Aparna IN, Pai KM. Prosthetic Rehabilitation of a Complete Bilateral Maxillectomy Patient Using a Simple Magnetically Connected Hollow Obturator: A Case Report. J Contemp Dent Pract 2008 January; (9)1:070-076.
Treatment Considerations for a Patient with Hypohidrotic Ectodermal Dysplasia: A Case Report
Authors: Tüfekcioğlu Dilek , Bal Chenkhan , Bal Bilge Turhan 
Published: July 2019

AbstractAimThis clinical report describes the oral rehabilitation of a 6-year-old male ectodermal dysplasia (ED) patient diagnosed with hypodontia.BackgroundED is a hereditary disease characterized by a congenital dysplasia of one or more ectodermal structures and their accessory appendages. Common manifestations include defective hair follicles and eyebrows, frontal bossing with prominent supraorbital ridges, nasal bridge depression, and protuberant lips. Intraorally, most common findings are anadontia or hypodontia, conical teeth, and generalize spaces. The patient may suffer from dry skin, hyperthermia, and unexplained high fever as a result of deficiency of sweat glands.ReportA six-year-old boy who exhibited many of the manifestations of ED as well as behavioral problems and a severe gag reflex. The treatment was designed to improve his appearance and oral functions and included the fabrication of several removable prostheses and acid-etched composite resin restorations during his growth and development.SummaryYoung patients with ED need to be evaluated early by a dental professional to determine the oral ramifications of the condition. When indicated, appropriate care needs to be rendered throughout the child's growth cycle to maintain oral functions as well as to address the esthetic needs of the patient. This clinical report demonstrates that removable partial dentures associated with direct composite restorations can be a reversible and inexpensive method of treatment for young ED patients.CitationBal C, Bal BT, Casela L, Tüfekçioğlu D. Treatment Considerations for a Patient with Hypohidrotic Ectodermal Dysplasia: A Case Report. J Contemp Dent Pract 2008 March; (9)3:128-134.
Arthroscopy vs. Open-joint Surgery for the Management of Internal Derangement of the Temporomandibular Joint: A Retrospective Study Comparing Female Subjects from Two Centers
Authors: Almas Khalid , Hobeiche Joseph , Tashkandi Esam 
Published: July 2019

Abstract

Aim
The aim of this retrospective study was to assess the treatment outcome of arthroscopy and open-joint surgery in the management of internal derangement of the temporomandibular joint (TMJ).

Background
Apart from pain being the major complaint in patients with temporomandibular joint disorders (TMDs), a variety of function-related symptoms are reported including joint noises, locking, limited movement, and alterations in occlusion. Surgical management procedures of internal derangement of the TMJ vary widely at present. The criteria for the assessment of successful outcome of the treatment are also variable.

Methods and Materials
The retrospective study was carried out at two centers in Paris and Beirut. Sixty-two female patients with an age range of 35.1 years (28 had arthroscopy and 34 had open surgery) were included in the study. The patients were followed-up for 12 months. A standardized questionnaire and visual analogue scale (VAS) was developed and used for the assessment of pain and mandibular range of motion. A chi-square test was used to observe the significance of difference among both groups.

Conclusion
Within the limitations of this study, it was concluded arthroscopic surgery appeared to be safe with pain reduction and increased mandibular range of motion for 80% of the patients. Further research is needed on a larger prospective sample to assess the comparison of both techniques in terms of enhanced quality of life among the study population.

Clinical significance
Arthroscopic surgery appears to be a safe, minimally invasive, and effective method for treating internal derangements of the TMJ.

Citation
Hobeiche J, Salameh Z, Tashkandi E, Almas K. Arthroscopy vs. Open-joint Surgery for the Management of Internal Derangement of the Temporomandibular Joint: A Retrospective Study Comparing Female Subjects from Two Centers. J Contemp Dent Pract 2008 March; (9)3:048-055.