bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetic Polymorphism of Interferon-Gamma +874T/A as a Risk Factor for Pulmonary Tuberculosis in Cirebon, Indonesia
Authors: Kiteswara Allain Umadela Deuxawalu , Sari Ariestya Indah Permata , Pratamawati Tiar Masykuroh 
Published: December 2024

Background: Tuberculosis (TB) is one of the leading causes of death globally, caused by Mycobacterium tuberculosis. With 10% of all cases worldwide in 2022, Indonesia is the second-largest contributor of tuberculosis cases. IFN-γ gene polymorphism is one of the factors that have been studied extensively for its association with TB.
Aims: To analyze IFN-γ +874T/A gene polymorphism as a risk factor for pulmonary tuberculosis in Cirebon.
Methods: Observational analysis with case control design was used in this study. Thirty-two tuberculosis patients as cases and 32 healthy controls at RSUD Waled were collected and performed DNA extraction to evaluate the polymorphism by using Amplification-refractory mutation system–polymerase chain reaction (ARMS–PCR). Statistical comparison was performed by using Pearson Chi-square and Kruskal Wallis test. Mann-Whitney U test was done for post hoc test. Odds ratio was calculated to see the risk of the assessed variables, including genotype, allele frequency, and the presence of polymorphism.
Results: In the case group, the frequency of TT genotype was 3 (9.4%), TA genotype was 26 (81.3%), AA genotype was 3 (9.4%). In the control group, the frequency of TT genotype was 12 (37.5%), TA genotype was 17 (53.1%), AA genotype was 3 (9.4%). A significant difference (p=0.034) was found among 3 genotype groups. Post hoc test revealed that TT and TA was the pair with significant difference (p=0.007). In addition, TA polymorphism was significantly associated (p=0.004) with tuberculosis (OR=6.614; CI95% = 1.660-26.349).
Conclusion: IFN-γ +874 TA gene polymorphism is associated with pulmonary tuberculosis in the population of Cirebon, West Java, Indonesia.

Received: 25 September 2024 | Reviewed: 23 October 2024 |
Revised: 10 November 2024 | Accepted: 30 November 2024
Unveiling the hidden dynamics: role of HRM in supporting the health and safety of healthcare workers in the post-Covid 19 pandemic world of work: an integrative review
Authors: Bangura Samuel 
Published: December 2024

The main purpose of the study was to uncover the hidden dynamics of HRM's role in supporting the health and safety of healthcare workers in the current world of work. It specifically focuses on an integrative review conducted in Durban, Republic of South Africa. In terms of design, that study approaches an integrative review conducted on 26 research articles and journals from reputable sources such as Google Scholar and Ebsco-host. The focus of the review was on the impact of human resource management on the well-being of healthcare workers during the COVID-19 pandemic. A total of 200 results were collected and categorised based on specific inclusion criteria, with a focus on the intersection of HRM, COVID-19, and healthcare workers. The inclusion criteria are premised on the fact that articles that did not directly address how HRM can improve the performance and safety of healthcare workers were excluded. The authors carefully reviewed the abstracts and titles of the articles to ensure they met the inclusion criteria. After removing duplicate entries, 26 articles were identified as relevant to the study and were analysed alongside other pertinent literature. The findings of this study highlight the significant impact of human resource management in effectively addressing challenges related to the healthcare workforce during crises, such as the COVID-19 pandemic. The originality of the study is grounded on the significance of HRM as a key stakeholder in workforce operations. Therefore organisational management must acknowledge this role. This is evident in the recommendation of the 6Cs of HRM as a pathway to effectively manage the health and safety of healthcare workers. For Future Research the fact that the study highlights the significance of HRM in organisations during times of crisis, such as a pandemic. It is important to recognise the necessity for further research employing quantitative or mixed methods to obtain a comprehensive understanding of how HRM plays a crucial role in effectively addressing and managing healthcare workers amidst challenging situations.
Hybrid governance in selected African countries:
Authors: Hendrickse Rozenda 
Published: December 2024

Governance is still a contested concept in both theory and practice. A proliferation of the concept has sprung up in literature. One comes across variations where reference is made to co-production, public governance, good governance, hybridity governance, hybrid governance, to name but a few. The aim of this paper is to provide a conceptual overview of the evolution of the concept governance in general and hybrid governance particulary focused on selected African countries. It is important to clarify what hybrid governance involves, and its implications for state capacity and service delivery. Furthermore, it is imperative to discern whether hybrid governance could be a useful conceptual tool for facilitating more organised systems of service delivery in parts of Africa and South Africa, or whether it is just “new developmental jargon”. The paper employed a qualitative research approach where secondary sources of information, constituting document analysis, premised around forms of hybrid governance in selected African countries were explored. The paper makes a conceptual contribution to the collaborative international governance discourse.
Peningkatan Brand dan Product Value Pathilo
Authors: Hamdan Anwari  , Arif Dwi Saputra  , Alfina Damayanti  , Wafiroh  , Noverinto Gilang  , Oris Umbu Laki Nuga  
Published: December 2024

Improving the Brand and Product Value of Pathilo
The Community Self-Reliance Program through the Community Service Scheme is an activity initiated by the Sekolah Tinggi Pariwisata AMPTA Yogyakarta Institute of Tourism and Community Service, which is intended to provide assistance and training to increase the brand and product value of Pathilo' as locally processed products. The mentoring and training activities are expected to produce output and achievement from Pathilo Brand. Product Value Improvement activities in Pakel, Tepus, Gunungkidul is a manifestation of public awareness, especially Pathilo local product business owners, in branding products so that businessmen of small and medium enterprise have selling value for potential consumers Pathilo's processed products are wrong commodity for the local community and a choice of souvenirs for tourists visiting the Tepus Tourism Village. Even so, the interest and views of the broader community towards this refined product are mediocre. This is due to the need for branding of the product itself. In addition, the public and business actors have yet to utilize digital platforms for marketing, and there has been no innovation in these processed products, which makes the products look dull and unattractive. Therefore, this service activity aims to increase branding and create value from Pathilo products
منهج أئمة أهل البيت(عليهم السلام) في حل اشكال وتفسير آيات المحو والاثبات (البداء)
Authors: كاظم انور , الاعرجي مهند 
Published: December 2024

اتفقت الإمامية وطبقاً للنصوص القرآنية المباركة والأحاديث الواردة النبي محمد(صلى الله عليه وآله وسلم) وأئمة أهل البيت(عليهم السلام) على أحقية (البداء) بالمعنى الذي تقصده لا بالمعنى الذي قال به غيرهم, مستندين ايضاً ألى حجية العقل في ذلك على أنه تعالى عالم بكل الأشياء وهو أزلي العلم وإن علمه سبحانه فيما كان و ما هو كائن في الحاضر وما هو سيكون في المستقبل له الأحاطة بجميع الأشياء’ وليس علمه بظهور الأشياء بعد خفائها عليه, وهذا محالاً على الله تعالى, لكنه تعالى قد علق بعض أفعال العباد بأنفسهم حيث أن الأنسان هو صاحب المصير والتغيير وأن الله تعالى يثيب ويعاقب على قدر أفعال الأنسان, وهذا ما إشارت إليه النصوص القرآنية والأحاديث الشريفة منها أن صلة الأرحام تطيل الاعمار ودفع الصدقة على فقراء المسلمين تدفع البلاء, وهذا هو الأساس الذي تقصده الأمامية في معنى (البداء) وتؤول إليه لا لغيره كحدوث العلم بالأشياء والجهل بها مسبقاً من قبله تعالى كونه يستوجب النفص في مقام الإلوهية وعلم الله تعالى نافذ في المخلوقات أزلاً و على نحو الأطلاق الأبدي, وكذلك من المضاميين التي تحويها العقيدة في (البداء) هو توسل العبد وانقطاعه لله (عز وجل) من أجل استجابة الدعاء , وكفاية مهماته, واستمرار التعبد له وابعاده عن المعصية والوقوع في الشبهات, وهذا خير دليل على أحقية البداء وعدم انكاره, أما الذين قالوا ببطلان البداء وانكاره إذ كان الأساس في انكاره هو الفهم اللفظي المعنوي االمغلوط لعقيدة البداء التي قال بها الإمامية حيث يعتبرونه كفراً لاذعاً بحقه تعالى كون العقيدة في البداء تستلزم العلم بعد العجز والجهل لله تعالى وهذا يستحيل عليه سبحانه؛ لأنه سبحانه له القدرة والعلم المطلق حتى قيام الساعة, بل المراد هو أن الأنسان مختاراً في أفعاله وتصرفاته وأن البداوات التي تظهر للإنسان نتيجة تلك الافعال التي يقوم بها لكن هذا لا يعني أن الله تعالى ليس له العلم بهذا الحدوث بل مشيئته وأرادته تحيط على جميع الأشياء وحدوثها.
التحليل المكاني للاصابات بمرض التهاب الكبد الفيروسي في محافظة بابل لعام 2010-2020
Authors: نهابة فريال , الشريفي سحر 
Published: December 2024

يهدف هذا البحث الى معرفة التوزيع المكاني لاصابات مرض التهاب الكبد الوبائي نوع في محافظة بابل وذلك لغرض اعطاء صورة واضحة عن الواقع الجغرافي للمرض كون الظاهرة المرضية هي ظاهرة جغرافية وللمكان اثر كبير في تباين وجودها وقد تم تمثيل نسب التوزيع الخرائط عادة للوصف والتحليل التي بدورها تساعد في معرفة اماكن تركز المرض وانتشاره وبعدها يمكن تفسير ظهور المرض وانتشاره مكانيا، لان المكان يحتوي على العوامل الطبيعية والبشرية التي تساعد في توفير عوامل ظهور وانتشار المرض، يختلف نوع الوبائي لمرض التهاب الكبد الفايروسي في محافظة بابل خلال مدة الدراسة فهو لم يظهر على وتيرة واحدة ، فمن خلال دراسة التباين المكاني والزماني ، اذ سجلت اعلى نسبة موسمية لاصابات ووفيات النوعين (A) و (E) خلال اشهر فصل الصيف ، في حين سجلت اعلى نسبة لمرض التهاب المرض الكبد الفايروسي نوع (B) ونوع (C) خلال فصل الخريف في شهر تشرين الاول اما بالنسبة للعوامل البشرية للمصابين بمرض التهاب الكبد تبين ان المرض يصيب كلا الجنسين وكما يظهر بجميع الفئات العمرية ، وهناك تباين في نسب اصابات ووفيات كلا الجنسين مع ارتفاع نسبة الذكور في جميع انواع المرض.
الأحكام النحويّة للأسماء بين الفرّاء والطوسي
Authors: لفته حامد , عبد عقيل 
Published: December 2024

يكشف هذا البحث عن بعض الأحكام النحوية المختصة بالأسماء ، التي يخالف فيها الفرّاء البصريين ، وبعض الأحكام التي ، توافق فيها مع البصريين وخالفه الكوفيون ، وقد نقلها عنه الشيخ الطوسي في التبيان في تفسير القرآن ، ومن ثم يكشف عن مدى موافقة الشيخ الطوسي للفرّاء أو مخالفته له فيها .
وقد سلط هذا البحث الضوء على حكم العطف على الضمير المرفوع من غير توكيد ولا فصل ، وحكم ترك الاخبار عن المبتدأ ، وحكم إضافة الاسم الى ما يرادفه ، وحكم الفصل بين المضاف والمضاف إليه ، وحكم مجيئ التمييز معرفة .
دور خليل الوزير في تأسيس حركة التحرير الوطني الفلسطيني "فتح" (1956-1959)
Authors: كاظم عذراء , حسين يوسف 
Published: December 2024

انتقل خليل الوزير إلى مصر لإستكمال دراسته، وتزامن ذلك مع العدوان الثلاثي فساند مصر من خلال المشاركة في المقاومة الشعبية وعلى أثر مهاجمته اهداف إسرائيلية فقد مقعدة الجامعي، ثم سافر إلى السعودية للعمل مدرساً، بعد انتقاله إلى الكويت عام 1958 أتفق مع ياسر عرفات على تأسيس تنظيم سري بهدف تحرير فلسطين عبر الكفاح المسلح، وفي عام 1959 أنتقل إلى بيروت في تشرين الثاني عام 1959 بعد تكليفه لتحرير مجلة "فلسطينا".
A Critical Discourse Analysis of BBC News Headlines about Al-Aqsa Flood Operation Against Israel
Authors: Hasan Ali 
Published: December 2024

This study aims to examine the portrayal of Hamas in the headlines of the BBC agency, with the purpose of revealing the linguistic representation and any underlying ideology. This study will analyze (21) headlines related to the Al-Aqsa Flood Operation Against Israel. Leeuwen's model (2008) analyzes these headlines to answer the study's questions. This analysis concludes that Hamas is more frequently included rather than excluded.
Hamas is represented as a negative entity by different strategies like "categories: generalization, assimilation, association, determination, identification, functionalization personalization, Activation, and Passivation." The BBC frequently uses negative vocabulary, such as
"control, capture, seize, attack, fall, assault and kill" to portray Hamas forces as assailants, which is the source of this negative mindset. According to the investigation, the BBC agency showed Hamas as an active and dynamic social player on a negative level.
مؤشرات الاقراض المصرفي وتأثيرها في السلامة المالية (دراسة تحليلية لعينة من المصارف التجارية المدرجة في سوق العراق للأوراق المالية للمدة من (2014-2021))
Authors: عبيد علي 
Published: December 2024

تهدف الدراسة الحالية إلى اختبار دور مؤشرات الاقراض المصرفي المتمثلة بـ (نسبة القروض, توظيف الارباح المحتجزة وجودة القروض) كمتغير مستقل في السلامة المالية كمتغير تابع، إذ اعتمدت الدراسة عدة مؤشرات لقياس المتغيرات. إذ تحددت مشكلة الدراسة بعدد من التساؤلات كان أهمها ما مدى إسهام مؤشرات الاقراض المصرفي في تحقيق السلامة المالية في المصارف التجارية المدرجة في سوق العراق للأوراق المالية؟ ومن أجل تحقيق أهداف الدراسة والإجابة عن تساؤلاتها، تم اختيار مجتمع الدراسة المتمثل بالمصارف التجارية المساهمة المدرجة في سوق العراق للأوراق المالية والبالغ عددها (23) مصرفاً، وتم اختيار عينة مكونة من (7) مصارف تجارية مساهمة توفرت بياناتها للفترة الزمنية (2014-2021) بالاعتماد على بيانات الموقع الالكتروني الرسمي لسوق العراق للأوراق المالية، وتم اختبار فرضيات التأثير باستخدام البرنامج الإحصائي (Eviews-10). وتم تحليل البيانات على وفق أسلوب الانحدار المتعدد.
وتوصلت الدراسة إلى مجموعة من الاستنتاجات كان أهمها تعد مؤشرات الاقراض المصرفي مؤشرات هامة لتحقيق سلامة مالية تضمن وجود المصارف المبحوثة في عالم الاعمال ، مما يتطلب من ادارة المصارف ادارة تلك المؤشرات بالشكل الذي يضمن استمرار السلامة المالية للمصارف.
The Diversity of Oil Palm Weeds Results in The People's Oil Palm Plantations in Kuantan Singingi Regency
Authors: Andriani Desta , Wahyudi  
Published: December 2024

Weeds are defined as plants that have the potential to disrupt or harm human interests, and as a result, humans have developed methods to control their proliferation. The weeds in oil palm plantations exhibit considerable diversity, encompassing grasses, sedges, and woody plants. This research aims to ascertain the diversity of weed species present in mature oil palm plantations in the Kuantan Singing District. The research was conducted using the proposed random sampling method. Data were collected through direct interviews, which included information such as the age of the plant and the type of herbicide and fertilizer used. The weed vegetation was analysed using the quadrant method on each plot of land. The observation plots were 10 m x 10 m in size, with 25 plots in each garden. The weeds are identified at each observation point through a visual examination of their morphological characteristics, which are then matched with those described in the relevant literature. The observations of plantation conditions indicate that the predominant age of the oil palm is 5-7 years, with a planting distance of 8x9 metres. The soil types observed in each plantation area included black sandy, white sandy, and rocky, with black sandy soil representing the dominant soil type. Farmers employ both mechanical and chemical techniques to control weeds. The frequency of control is once every three months. A total of 14, 12, and 9 weed species were identified in the Central Kuantan, Inuman, and Sintajo Raya sub-districts, respectively. The results of the observation of the types of weeds found in the people's coconut plantations on yield crops revealed the presence of five types of narrow-leaf weeds, ten types of broad-leaf weeds, and four types of fern weeds.
O ensino de História e a História Pública Digital
Authors: Rivaben Pereira Renan 
Published: December 2024

Anelize Vergara é mestra pela Universidade Estadual de São Paulo e sua dissertação aproximou a história e a literatura ao abordar as crônicas de Rubem Braga na época do Estado Novo.[1] Em 2018, ela criou o canal no Youtube Profa Anelize e passou a produzir vídeos com conteúdo de História para jovens estudantes e vestibulandos. Quase quatro anos depois, o canal está prestes a atingir 40 mil inscritos e Anelize também obtêm números expressivos de popularidade em outras redes sociais. Hoje, ela divide sua atuação como professora do Ensino Básico e a produção de conteúdo, inclusive para professores de história, em várias redes sociais. Nessa entrevista, abordaremos suas experiências e visões sobre o ambiente acadêmico, a História Pública Digital e as possibilidades que as redes digitais oferecem para o cientista e o professor em tempos de alta de discursos autoritários e anticientíficos.

[1] VERGARA, Anelize. Rubem Braga: crônica e censura no Estado Novo (1938-1939). 2014. 164 f. Dissertação (mestrado) - Universidade Estadual Paulista, Faculdade de Ciências e Letras de Assis, 2014. Disponível em: <http://hdl.handle.net/11449/113808>.
O acervo arquivístico da Comarca de Bragança - PA de 1964-1985 e a função social dos arquivos judiciários produzidos no contexto da ditadura civil-militar
Authors: De Sousa Miranda Filipe 
Published: December 2024

Tomando como referência o acervo arquivístico acumulado pela Comarca de Bragança-PA no período de 1964-1985, o presente artigo objetiva discutir a importância dos arquivos judiciários produzidos no contexto da ditadura civil-militar enquanto instrumentos que viabilizam a efetivação do direito à informação, à história, à memória, à verdade, à justiça e à reparação. A metodologia empregada compreende pesquisa bibliográfica e documental. O texto congrega debates atinentes ao papel social dos arquivos legados por extintos regimes autoritários e ditatoriais na consolidação das democracias contemporâneas, a atuação do Poder Judiciário após o golpe civil-militar militar de 1964 e as potencialidades dos acervos arquivísticos reunidos pelo órgão durante 21 anos de ditadura para o devir de memórias e histórias que vão de encontro a uma “memória obrigada”, consolidada institucionalmente.
Efectividad diagnóstica del electrocardiograma en cardiopatías congénitas en menores de 2 años
Authors: De León Tenaz Javier Andrés , Fernández Cifre Daniela Michele 
Published: December 2024

Introducción: Las cardiopatías congénitas tienen una alta incidencia a nivel mundial, es la principal causa de enfermedades crónicas en pediatría. Su identificación incluye sospecha clínica, la realización de estudios complementarios tal como la electrocardiografía como tamizaje y el ecocardiograma como el «estándar de oro». Objetivo: Determinar la utilidad diagnóstica del electrocardiograma para la detección de cardiopatías congénitas en niños menores de 2 años. Metodología: Estudio cuantitativo, analítico y transversal de 146 pacientes menores de 2 años, a quienes se les realizó un electrocardiograma y ecocardiograma transtorácico para posteriormente comparar ambos resultados. Resultados: Del total de los pacientes estudiados, el 55.48 % son masculinos y el 72.6 % tenían entre 0 y 6 meses de edad. Los hallazgos electrocardiográficos fueron compatibles con persistencia del ductus arterioso (27.3 %), comunicación interventricular (12 %) y comunicación interauricular (8.7 %). Estos diagnósticos coincidieron con los observados en la ecocardiografía correspondiente. Se demostró una sensibilidad del 94 %, especificidad del 100 %, valor predictivo positivo del 100 % y valor predictivo negativo del 92.1 %. Conclusiones: En la población estudiada, el electrocardiograma demostró ser una prueba diagnóstica de tamizaje con una alta sensibilidad, especificidad, y adecuados valores predictivos positivo y negativo para identificar la presencia de cardiopatías congénitas en niños menores de 2 años.
Validation of a modified Russian-language version of the Norwegian “Patient Experience Questionnaire”
Authors: Ionov M. V. , Dubinina E. A. , Zvartau N. E. , Konradi A. O. 
Published: December 2024

To date, there are no specific scales in the Russian Federation for the comprehensive assessment of patient satisfaction and experience of outpatient medical care.Objective. To validate the previously translated Norwegian "Patient Experience Questionnaire" (PEQ), a validated patientreported experience measure (PREM) for outpatients.Materials and methods. Patients aged over 18 years were invited to complete the questionnaire within 24 h after visiting a physician by clicking on a link in the QR [quick response] code printed on the medical report. The construct, discriminant validity, and reliability of individual questions, domains, and the entire questionnaire were analyzed.Results. A total of 452 patients (47.3% male, median age 55 [38–68] years) completed the questionnaire. Less than 18% of the responses were missing. These responses were considered "missing at random". Most patients in this cohort had higher education (67.7%), were married (58%), and were seen by a female physician (91.4%). In confirmatory factor analysis, the factor loadings of the questions were all above 0.6 units, and the reliability of each question, individual scales, and the entire questionnaire was above 0.8 units. The overall questionnaire model met all the goodness-of-fit criteria.Conclusions. The construct and discriminant validity of the previously translated into Russian language Patient Experience Questionnaire, has been confirmed. This PREM is proposed to be used in routine clinical practice and scientific studies under the name "RuPEQ".
Anti-infective drugs as etiologic factors for Stevens–Johnson syndrome and toxic epidermal necrolysis according to the Russian database of spontaneous reports
Authors: Terekhina E. N. , Asetskaya I. L. 
Published: December 2024

Relevance. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are serious adverse drug reactions (ADRs) associated with drug use. Knowledge of drug triggers is important for ADR prevention.Objective. To study the structure of anti-infective drugs that cause the development of SJS and TEN.Methods. We studied spontaneous reports (SRs) submitted to the Russian National Pharmacovigilance database from 01.04.2019 to 31.12.2023. SRs about the development of SJS or TEN were included. Suspected drugs in group J according to the ATC classification were analyzed.Results. Among the 170 included SRs, anti-infectives were noted as suspects in 69, and the total number of drugs was 103. 75 drugs were antibacterial (beta-lactams were leading, n = 46), and 21 were antiviral agents.Conclusion. In terms of the structure of anti-infective drug triggers, 72.8% were antibacterial drugs and 20.4% were antiviral agents.
Analysis of spontaneous reports from a pediatric population: Stevens–Johnson syndrome and toxic epidermal necrolysis induced by antibacterial drugs
Authors: Kustov Yu. O. , Terekhina E. N. , Asetskaya I. L. , Butranova O. I. 
Published: December 2024

Relevance. Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are cutaneous hypersensitivity reactions that can be induced by drugs and are particularly severe in children.Objective. To study the structure of antibacterial drugs (ABs) involved in the development of SJS and TEN in pediatric populations.Methods. Retrospective pharmacoepidemiologic study of spontaneous reports (SRs) entered into the Russian National Pharmacovigilance database during the period 01.04.2019 – 31.12.2023.Results. The majority of suspected drugs were β-lactams (76.0%), with penicillin accounting for 47.4% and cephalosporins — for 52.6%. Amphenicols (12.0%), macrolides (8.0%), and fluoroquinolones (4.0%) were less frequently reported.Conclusion. The most common group of ABs that induce SJS and TEN in children is the group of β-lactam antibiotics.