bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fractures of The Tibial Plafond: Does the Presence or Absence of a Fibular Fracture Predict Future Morbidity?
Authors: Boateng Henry , Nwachuku Chinenye , Walley Kempland C. , Walker Justin W. , MacNeille Rhett , Tornetta Paul , Reid Spence 
Published: May 2019

Category: Trauma Introduction/Purpose: Surgical management pilon fractures continue to be a challenge for orthopedic surgeons. Despite a staged protocol, anatomic reduction, and stable fixation, many patients will require secondary procedures including ankle arthrodesis to treat painful post-traumatic arthritis. Some investigators have correlated the absorbed energy at the time of the injury with the natural history of the pilon fracture despite the quality of the surgical reconstruction. We hypothesize that the presence of an intact fibula in association with an OTA Type C pilon fracture may be a marker for a strict axial compression mechanism resulting in more severe cartilage compression and a poor late outcome. No studies to date have correlated the presence of an intact fibula to pilon fracture outcome. Methods: An IRB approved 7-year retrospective study was performed at three Level I Trauma Centers. Inclusion criteria included all adult patents (=18) with isolated OTA type B or C pilon fractures from 2008 through 2014. All patients were treated in a staged fashion with initial external fixation by fellowship-trained orthopedic traumatologists. The primary outcome measurement was ankle arthrodesis. Secondary measurements included infection. Binary logistic regression models were used to evaluate prognostic factors of arthrodesis and infection. A total of 239 patients met inclusion criteria for a complete case analysis. Results: It was found that OTA Type C pilon fractures (OR (95% CI): 6.34 (0.80, 49.98), p=0.08), intact fibulas (OR (95% CI): 1.39 (0.43, 4.53), p=0.58), and open injuries (OR (95% CI): 2.19 (0.56, 8.55), p=0.26) were more likely to result in eventual arthrodesis compared to OTA Type B pilon fractures, fractured fibulas, and closed injuries, respectively. However, none of these unadjusted bivariate associations were statistically significant. An intact fibula was significantly less likely to result in infection compared to having a fractured fibula (OR (95% CI): 0.26 (0.08, 0.90), p=0.03), however this effect was no longer significant after accounting for open versus closed injury status (Adjusted OR (95% CI): 0.35 (0.10, 1.26), p=0.11). Conclusion: The results of this study suggest an adverse relationship for closed complex pilon fractures with an intact fibula. This was especially pronounced in C type injuries in comparison to type B injuries with a 6.34 odds ratio of subsequent fusion. The data approached statistical significance and may have clinical relevance in the decision making and patient counselling for managing these fractures. Pilon fractures historically have had poor outcomes and a higher rate of secondary surgeries which was surprisingly low in our current study. Further study needs to determine if this observation correlates with improved patient outcomes.
Intraretinal Migration of Emulsified Silicone Oil: Association With Cystoid Macular Edema and Surgical Treatment
Authors: Chantarasorn Yodpong , Eliott Dean 
Published: May 2019

Purpose: The purpose of this article is to report the detailed stages of intraretinal silicone oil infiltration, and to describe a new surgical treatment for this condition. Methods: An observational case series is presented. Results: We report 2 patients who had undergone repair of complex diabetic retinal detachment and subsequently developed intraretinal migration of emulsified silicone oil, cystoid macular edema (CME), and lamellar macular hole (LMH). Surgical removal of the incarcerated oil bubbles rapidly restored foveal anatomy in both cases. Possible risk factors for intraretinal oil migration are discussed. Conclusions: Emulsified silicone oil droplets can penetrate the retina, resulting in CME and LMH. While severe CME in this setting is usually recalcitrant to pharmacotherapy, vitrectomy with expression of oil droplets may result in rapid and longstanding resolution.
Structural basis of the leukocyte integrin Mac-1 I-domain interactions with the platelet glycoprotein Ib
Authors: Morgan Juliet , Saleem Muhammad , Ng Ruiqi , Armstrong Caroline , Wong Szu S. , Caulton Simon G. , Fickling Alice , Williams Huw E. L. , Munday Adam D. , López José A. , Searle Mark S. , Emsley Jonas 
Published: May 2019

AbstractCell-surface receptor interactions between leukocyte integrin macrophage-1 antigen (Mac-1, also known as CR3, αMβ2, CD11b/CD18) and platelet glycoprotein Ibα (GPIbα) are critical to vascular inflammation. To define the key residues at the binding interface, we used nuclear magnetic resonance (NMR) to assign the spectra of the mouse Mac-1 I-domain and mapped the residues contacting the mouse GPIbα N-terminal domain (GPIbαN) to the locality of the integrin metal ion-dependant adhesion site (MIDAS) surface. We next determined the crystal structures of the mouse GPIbαN and Mac-1 I-domain to 2 Å and 2.5 Å resolution, respectively. The mouse Mac-1 I-domain crystal structure reveals an active conformation that is stabilized by a crystal contact from the α7-helix with a glutamate side chain completing the octahedral coordination sphere of the MIDAS Mg2+ ion. The amino acid sequence of the α7-helix and disposition of the glutamic acid matches the C-terminal capping region α-helix of GPIbα effectively acting as a ligand mimetic. Using these crystal structures in combination with NMR measurements and docking analysis, we developed a model whereby an acidic residue from the GPIbα leucine-rich repeat (LRR) capping α-helix coordinates directly to the Mac-1 MIDAS Mg2+ ion. The Mac-1:GPIbαN complex involves additional interactions consolidated by an elongated pocket flanking the GPIbαN LRR capping α-helix. The GPIbαN α-helix has an HxxxE motif, which is equivalent by homology to RxxxD from the human GPIbαN. Subsequent mutagenesis of residues at this interface, coupled with surface plasmon resonance studies, confirmed the importance of GPIbαN residues H218, E222, and the Mac-1 MIDAS residue T209 to formation of the complex.
Quantitative evaluation method for clarifying ankle plantar flexion angles using anterior drawer and inversion stress tests: a cross‐sectional study
Authors: Kikumoto Takanori , Akatsuka Kazuma , Nakamura Emi , Ito Wataru , Hirabayashi Ryo , Edama Mutsuaki 
Published: May 2019

AbstractBackgroundChronic ankle instability (CAI) may result from repeated, frequent ankle sprains during sports activities. Manual examination for CAI is conducted; however, quantitative methods for the evaluation of CAI have not been established, and the reproducibility of the amount of stress is low. This cross‐sectional study aimed to use a stress device and ultrasound for the quantitative evaluation of the change in the length of the anterior talofibular ligament (ATFL) during simulated anterior drawer and ankle inversion stress tests.MethodsQuestionnaires were provided to 160 healthy college students (86 men, 74 women; 320 ankles). We extracted two groups from them: control subjects without a history of ankle injury (n = 64 ankles) and subjects with CAI (n = 54 ankles). We calculated the change in the length of the ATFL with anterior drawer and inversion stress tests at ankle joint plantar flexions of 0°, 20°, and 45° using ultrasound images.ResultsThe anterior length change rates were significantly higher in the CAI group than in the control group at ankle joint plantar flexions of 20° and 45° in men (P < 0.05). The inversion length change rates were significantly higher in the CAI group at ankle joint plantar flexion of 20° in men (P < 0.05). No significant between‐group difference in the anterior and inversion length change rates was observed in women.ConclusionsStress ultrasound revealed greater length changes in the ATFL in the CAI group than in the control group. The stress test may be useful at ankle joint plantar flexion of 20° for men.
The Meeting of Revolutionary Roads: Chilean-Cuban Interactions, 1959–1970
Authors: Pedemonte Rafael 
Published: May 2019

Abstract
Fidel Castro's endorsement of Salvador Allende's revolutionary program in August 1970 was determined by global transformations and changing priorities within both Chile and Cuba. Since 1968, favorable prospects for the Left encouraged Havana to abandon its radicalism premised on the inevitability of armed struggle. Prior to 1970 Chile gradually promoted rapprochement with the socialist world and lessened Cuba's hemispheric isolation, imposed by the Organization of American States. It is within this framework that the meeting between Cuba's and Chile's revolutions has to be understood. Allende, knowing that Castro's support would push the radical Left to side with Popular Unity in the 1970 elections, sent a delegation to convince the Cubans that socialism could be achieved by peaceful means. These events and strategic discussions within Chile and Cuba reveal how the history of the Left needs to be placed in a broad context defined by the complex unfolding of domestic, hemispheric, and international transformations shaping Latin America in the 1960s.
Comprometimento organizacional: estudo com recepcionistas de consultórios médicos de Belo Horizonte-MG
Authors: Ferreira Jesuina Maria Pereira , Rocha Michelle De Souza , Jerônimo Giselle Da Costa 
Published: May 2019

O objetivo desta pesquisa foi analisar o comprometimento organizacional por meio do modelo multidimensional de Meyer e Allen (1991), segundo a percepção de mulheres recepcionistas de consultórios médicos em Belo Horizonte-MG. Caracterizou-se esta pesquisa como de método misto (COLLIS; HUSSEY, 2006) e do tipo descritivo-exploratório (VERGARA, 2009). Utilizou-se para análise dos dados quantitativos o software Statistical Package for the Social Science (SPSS) e a análise de conteúdo (AC) (BARDIN, 2008) para apreciação das entrevistas. Na investigação quantitativa, constatou-se o predomínio da dimensão afetiva do comprometimento organizacional com média no nível moderado mais alto. Por outro lado, mesmo que nas análises qualitativas as dimensões afetiva e instrumental tenham sido predominantes nos relatos das mulheres entrevistadas, ao final, é por meio da dimensão afetiva que as recepcionistas permanecem na organização, significando que elas gostam e fazem seu trabalho por amor, valorizando o ambiente de trabalho e os relacionamentos interpessoais conquistados.
Laparoscopic Surgery in the treatment of children with Choledochal Cyst
Authors: Qu Xiushui , Cui Lihua , Xu Junchao 
Published: May 2019

Objective: To evaluate the clinical effectiveness of laparoscopic surgery in the treatment of children with choledochal cyst.
Methods: Seventy-six children with congenital choledochal cyst who were admitted to our hospital between February 2016 and April 2017 were selected as research subjects. They were evenly divided into an observation group and a control group using random number table, 38 each group. Patients in the observation group underwent laparoscopic surgery, while patients in the control group underwent the traditional laparotomy. Surgery related indicators and prognosis were compared between the two groups.
Results: The incision size and intraoperative bleeding volume of the observation group were significantly smaller than those of the control group (P<0.05). The time of passage of flatus and time to take food of the observation group were easier than those of the control group, and the duration of hospitalization and parenteral nutrition of the former was significantly shorter than those of the latter, and the difference had statistical significance (P<0.05). The incidence of postoperative complications in the observation group was 2.6%, significantly lower than that in the control group (10.5%) (P<0.05). There was no recurrence in the observation group during the follow-up period, but there were 5 cases of recurrence (13.1%) in the control group; the difference was statistically significant (P<0.05).
Conclusion: Compared with the traditional laparotomy, laparoscopic surgery conforms more to the concept of modern medical minimally invasive treatment and has a significant clinical effect in the treatment of congenital choledochal cyst in children. It can effectively promote the disappearance of clinical symptoms and signs, reduce the incidence of postoperative complications and disease recurrence, and improve the surgical efficacy, suggesting high clinical significance and application values.
doi: https://doi.org/10.12669/pjms.35.3.85
How to cite this:Qu X, Cui L, Xu J. Laparoscopic Surgery in the treatment of children with Choledochal Cyst. Pak J Med Sci. 2019;35(3):807-811. doi: https://doi.org/10.12669/pjms.35.3.85
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
O corpo intermediário. Uma aproximação fenomenológica
Authors: Falcón Luis Álvarez 
Published: May 2019

O presente texto procura sintetizar dez grandes teses que dão conta dos múltiplos níveis da experiência sobre o corpo. A origem destas considerações é radicalmente filosófica e as suas consequências afetam tanto o âmbito geral das artes quanto o próprio estatuto da filosofia. A fenomenologia é oprincipal marco teórico de referência. As proposições apresentam‑se como um recurso prático para ampliar a reflexão sobre o pensamento e a extensão sobre o corpo vivido, a espacialidade e a espacialização. A distinção, a separação, a distância, a interioridade, a exterioridade, a experiência do corpo interno (Leib) e do corpo externo (Körper) e os níveis de espacialidade serão algumas das questões críticas expostas. A distinção fenomenológica entre Phantasia e imaginação será a chave para pensar o desdobramento da subjetividade e do corpo depois da redução fenomenológica. Propomos, aqui, pensar o registo de um corpo intermediário ou de uma subjetividade média, que corresponde ao nível das Phantasias perceptivas, e cujos rendimentos são tanto estéticos quanto éticos, desenvolvidos pela filosofia fenomenológica.
Pragmatik Argümanlar ve İnanç
Authors: Tanış Abdülkadir 
Published: May 2019

Pragmatik argümanlar sınıfı içerisinde bazıları, belirli inançların edinilmesini teşvik etmek için tasarlanmıştır. İlginç biçimde, pragmatik argümanların bu alt sınıfı, en azından öncelikli olarak, doğruyu-amaçlayan argümanlar değildir. Doğruyu-amaçlayan argüman, bir önermenin doğru olduğunu düşünmek için gerekçelendirme sağladığı farz edilen argümandır. Pragmatik argüman, bir inancın edinimini, sadece bu inanca sahip olmaktan kaynaklanan menfaatler sebebiyle teşvik eden, menfaati-amaçlayan argümandır. Öyleyse, pragmatik argüman, belirli bir inancın oluşumunu ve devamlılığını, esas olarak, bu inanca sahip olmanın ortaya çıkardığı menfaatler sebebiyle teşvik etme çabasında olan bir argüman olarak tanımlanabilir.Bu tercüme, Delaware Üniversitesi Felsefe Profesörü Jeff Jordan'ın “Pragmatic Arguments and Belief” adlı makalenin tercümesidir. Makale, American Philosophical Quarterly,33/4 (1996), dergisinde s. 409-420 yayımlanmıştır.
On the Ito formula in a Banach Space
Authors: Mamporia B. 
Published: May 2019

Abstract
If (Wt
)
t∈[ 0, 1] is a Wiener process in an arbitrary separable Banach space X, ψ : [0, 1] × X → Y is a continuous function with values in another separable Banach space, and ψ has continuous Frechet derivatives , and , then the Ito formula is obtained for ψ(t, Wt
).
The method is based on the concept of covariance operator and a special construction of the Ito stochastic integral.
On the Rearranged Block-Orthonormal Systems
Authors: Nadibaidze G. 
Published: May 2019

Abstract
A condition is established for the sequence {Nk
} when there exists a rearrangement of functions of the block-orthonormal system {φn
} such that the sequence {log2
n} ({(log log n)2}) is a Weyl multiplier for the convergence (for the summability by the methods (C, α) (α > 0)) almost everywhere of series with respect to the rearranged system {φνn

}.
K-Convexity and Duality for Almost Summing Operators
Authors: Blasco O. , Tarieladze V. , Vidal R. 
Published: May 2019

Abstract
For a fixed sequence f. = (fn
) of independent identically distributed symmetric random variables with , we introduce the notion of Kf.
-convex Banach space and the notions of (fn
)-bounding and (fn
)-converging operators acting between Banach spaces. It is shown that the dual of the space of (fn
)-converging operators between a Hilbert space and a Kf.
-convex Banach space admits a precise description in terms of trace duality. The obtained results recover similar formulations for almost summing and γ-Radonifying operators.
Generalized Derivatives of an Arbitrary Order and the Boundary Properties of Differentiated Poisson Integrals for the Half-Space
Authors: Topuria S. 
Published: May 2019

Abstract
The notions of a generalized differential and a generalized spherical derivative of an arbitrary order are introduced for a function of several variables and Fatou type theorems are proved on the boundary properties of partial derivatives of an arbitrary order of the Poisson integral for the half-space, when the integral density has a generalized differential or a generalized spherical derivative.
On the Convergence and Summability of N-Dimensional Fourier Series with Respect to the Walsh–Paley Systems in the Spaces LP ([0, 1] N ), p ∈ [1, + ∞]
Authors: Goginava U. 
Published: May 2019

Abstract
The convergence and summability of N-dimensional Walsh–Fourier series in the metrics LP
([0, 1]
N
), p ∈ [1, + ∞], are studied by the negative order Césaro method. Getsadze's theorem and a generalization of Moricz' theorem are obtained as special cases.
On Multidimensional SDEs Without Drift and with A Time-Dependent Diffusion Matrix
Authors: Engelbert H. J. , Kurenok V. P. 
Published: May 2019

Abstract
We study multidimensional stochastic equations

where x
o is an arbitrary initial state, W is a d-dimensional Wiener process and is a measurable diffusion coefficient. We give sufficient conditions for the existence of weak solutions. Our main result generalizes some results obtained by A. Rozkosz and L. Słomiński [Stochastics Stochasties Rep. 42: 199–208, 1993] and T. Senf [Stochastics Stochastics Rep. 43: 199–220, 1993] for the existence of weak solutions of one-dimensional stochastic equations and also some results by A. Rozkosz and L. Słomiński [Stochastic Process. Appl. 37: 187–197, 1991], [Stochastic Process. Appl. 68: 285–302, 1997] for multidimensional equations. Finally, we also discuss the homogeneous case.
A Direct Boundary Integral Method for a Mobility Problem
Authors: Kohr Mirela 
Published: May 2019

Abstract
The problem of a Stokes flow in the presence of a solid particle, a rigid wall and a viscous cell is formulated as a system of Fredholm integral equations of the second kind, with the surface force on the boundary of the solid particle and the velocity on the interface as unknowns. The particularity of the problem consists in the fact that the total force and the total torque of the flow on the solid particle are zero. The existence and the uniqueness result of solution is obtained when the boundaries are curves of the class C
2.
A cyclic I10
2− anion in the layered crystal structure of theophyllinium pentaiodide, C7H9I5N4O2
Authors: Reiss Guido J. 
Published: May 2019

Abstract
C7H9I5N4O2, monoclinic, P21/c (no. 14), a = 9.46793(10) Å, b = 11.58276(12) Å, c = 16.41497(18) Å, β = 100.844(1)°, Z = 4, V = 1768.00(3) Å3, Rgt
(F) = 0.0306, wR
ref(F
2) = 0.0728, T = 130(2) K.
Metabolic pattern analysis of 18F-FDG PET as a marker for Parkinson’s disease: a systematic review and meta-analysis
Authors: Gu Si-Chun , Ye Qing , Yuan Can-Xing 
Published: May 2019

Abstract
A large number of articles have assessed the diagnostic accuracy of the metabolic pattern analysis of [18F]fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) in Parkinson’s disease (PD); however, different studies involved small samples with various controls and methods, leading to discrepant conclusions. This study aims to consolidate the available observational studies and provide a comprehensive evaluation of the clinical utility of 18F-FDG PET for PD. The methods included a systematic literature search and a hierarchical summary receiver operating characteristic approach. Sensitivity analyses according to different pattern analysis methods (statistical parametric mapping versus scaled subprofile modeling/principal component analysis) and control population [healthy controls (HCs) versus atypical parkinsonian disorder (APD) patients] were performed to verify the consistency of the main results. Additional analyses for multiple system atrophy (MSA) and progressive supranuclear palsy (PSP) were conducted. Fifteen studies comprising 1446 subjects (660 PD patients, 499 APD patients, and 287 HCs) were included. The overall diagnostic accuracy of 18F-FDG in differentiating PD from APDs and HCs was quite high, with a pooled sensitivity of 0.88 [95% confidence interval (95% CI), 0.85–0.91] and a pooled specificity of 0.92 (95% CI, 0.89–0.94), with sensitivity analyses indicating statistically consistent results. Additional analyses showed an overall sensitivity and specificity of 0.87 (95% CI, 0.76–0.94) and 0.93 (95% CI, 0.89–0.96) for MSA and 0.91 (95% CI, 0.78–0.95) and 0.96 (95% CI, 0.92–0.98) for PSP. Our study suggests that the metabolic pattern analysis of 18F-FDG PET has high diagnostic accuracy in the differential diagnosis of parkinsonian disorders.
Familial GATA6 mutation causing variably expressed diabetes mellitus and cardiac and renal abnormalities
Authors: Du Yang Timothy , Moore Lynette , Poplawski Nicola K , De Sousa Sunita M C 
Published: May 2019

Summary
A 26-year-old man presented with a combination of permanent neonatal diabetes due to pancreatic aplasia, complex congenital heart disease, central hypogonadism and growth hormone deficiency, structural renal abnormalities with proteinuria, umbilical hernia, neurocognitive impairment and dysmorphic features. His older brother had diabetes mellitus due to pancreatic hypoplasia, complex congenital heart disease, hypospadias and umbilical hernia. Their father had an atrial septal defect, umbilical hernia and diabetes mellitus diagnosed incidentally in adulthood on employment screening. The proband’s paternal grandmother had a congenital heart defect. Genetic testing of the proband revealed a novel heterozygous missense variant (Chr18:g.19761441T>C, c.1330T>C, p.Cys444Arg) in exon 4 of GATA6, which is class 5 (pathogenic) using American College of Medical Genetics and Genomics guidelines and is likely to account for his multisystem disorder. The same variant was detected in his brother and father, but not his paternal grandmother. This novel variant of GATA6 likely occurred de novo in the father with autosomal dominant inheritance in the proband and his brother. The case is exceptional as very few families with monogenic diabetes due to GATA6 mutations have been reported to date and we describe a new link between GATA6 and renal pathology.

Learning points:

Monogenic diabetes should be suspected in patients presenting with syndromic features, multisystem congenital disease, neonatal-onset diabetes and/or a suggestive family history.

Recognition and identification of genetic diabetes may improve patient understanding and empowerment and allow for better tailored management.

Identification of a genetic disorder may have important implications for family planning.