bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gigapixel big data movies provide cost‐effective seascape scale direct measurements of open‐access coastal human use such as recreational fisheries
Authors: Flynn David J. H. , Lynch Tim P. , Barrett Neville S. , Wong Lincoln S. C. , Devine Carlie , Hughes David 
Published: August 2018

AbstractCollecting data on unlicensed open‐access coastal activities, such as some types of recreational fishing, has often relied on telephone interviews selected from landline directories. However, this approach is becoming obsolete due to changes in communication technology such as a switch to unlisted mobile phones. Other methods, such as boat ramp interviews, are often impractical due to high labor cost. We trialed an autonomous, ultra‐high‐resolution photosampling method as a cost effect solution for direct measurements of a recreational fishery. Our sequential photosampling was batched processed using a novel software application to produce “big data” time series movies from a spatial subset of the fishery, and we validated this with a regional bus‐route survey and interviews with participants at access points. We also compared labor costs between these two methods. Most trailer boat users were recreational fishers targeting tuna spp. Our camera system closely matched trends in temporal variation from the larger scale regional survey, but as the camera data were at much higher frequency, we could additionally describe strong, daily variability in effort. Peaks were normally associated with weekends, but consecutive weekend tuna fishing competitions led to an anomaly of high effort across the normal weekday lulls. By reducing field time and batch processing imagery, Monthly labor costs for the camera sampling were a quarter of the bus‐route survey; and individual camera samples cost 2.5% of bus route samples to obtain. Gigapixel panoramic camera observations of fishing were representative of the temporal variability of regional fishing effort and could be used to develop a cost‐efficient index. High‐frequency sampling had the added benefit of being more likely to detect abnormal patterns of use. Combinations of remote sensing and on‐site interviews may provide a solution to describing highly variable effort in recreational fisheries while also validating activity and catch.
Anode‐Supported Planar Solid Oxide Fuel Cells Based on Double‐sided Cathodes
Authors: Liu Wu , Zou Zhiwen , Miao Fuxing , Li Xin , Wang Jianxin , Yang Jun , Wilson Joshua , Zhou Xiaodong , Zhong Zheng , Zhai Qijie , Guan Wanbing 
Published: August 2018

AbstractPlanar solid oxide fuel cells (SOFCs) have been extensively studied during the past few decades, particularly the anode supported SOFC. In traditional electrode‐supported cells, the mismatch of coefficients of thermal expansion between materials in each layer may give rise to thermal stresses during operation, resulting in micro‐cracks of ultra‐thin electrolytes, which may ultimately lead to operational damages and performance degradation. This work proposes a new symmetric, planar SOFC design based on double‐sided cathodes to offset asymmetry of thermal stresses within the structure. This new design has been applied to prepare an anode‐supported SOFC that maintains integrity after two complete redox cycles. Its anti‐fracture load is 20 times stronger than that of traditional ultra‐thin cells, and its electrochemical performance is close to that of traditional large‐scale, ultra‐thin cells. These properties are promising for application under harsh operational environments.
The FLC dimer with lambda type may false‐migrate to the position of “albumin” band by urine protein electrophoresis on Sebia agarose gel‐based detection system
Authors: Chen Changqiang , Chen Peizhan , Fang Xuqian 
Published: August 2018

BackgroundMonoclonal free light chains (FLC) commonly exist in monomeric or dimeric forms but rarely as larger molecules. Little is known about whether polymeric molecules can affect urine protein electrophoresis (UPE) results.MethodsUrine samples were collected from 72 multiple myeloma (MM) patients with Bence Jones protein (BJP). Urine protein and immunofixation electrophoresis were analyzed on Sebia SDS “agarose” gel electrophoresis system (SDS‐AGE), and immunoglobulin free light chains were measured on the BNII nephelometric assay.ResultsA type of disulfide‐bound FLC dimer shows a pattern shift to the position of the “albumin” band in urine protein electrophoresis in multiple myeloma (MM) patients according to the Sebia agarose gel‐based detection system, which was validated by immunofixation, SDS‐PAGE, and mass spectrometric methods. Similar cases were found in 21 (29.17%) of 72 MM patients with BJP, and 19 (90.5%) of 21 patients were the lambda type.ConclusionsThese results indicate that BJP with lambda type has a strong tendency to abnormally migrate, which may increase the risk of misinterpretation of protein electrophoresis in clinics. Thus, when the urine protein electrophoresis is inconsistent with the result by nephelometric method, urine protein electrophoresis needs to be repeated on the deduced condition to confirm the essence of the originally identified “albumin.”
Recent development trends for chiral stationary phases based on chitosan derivatives, cyclofructan derivatives and chiral porous materials in high performance liquid chromatography
Authors: Xie Sheng‐Ming , Yuan Li‐Ming 
Published: August 2018

AbstractThe separation of enantiomers by chromatographic methods, such as gas chromatography, high‐performance liquid chromatography and capillary electrochromatography, has become an increasingly significant challenge over the past few decades due to the demand of pharmaceutical, agrochemical, and food analysis. Among these chromatographic resolution methods, high‐performance liquid chromatography based on chiral stationary phases has become the most popular and effective method used for the analytical and preparative separation of optically active compounds. This review mainly focuses on the recent development trends for novel chiral stationary phases based on chitosan derivatives, cyclofructan derivatives, and chiral porous materials that include metal‐organic frameworks and covalent organic frameworks in high‐performance liquid chromatography. The enantioseparation performance and chiral recognition mechanisms of these newly developed chiral selectors toward enantiomers are discussed in detail.
Last ten years (2008–2018) of chiral ligand‐exchange chromatography in HPLC: An updated review
Authors: Ianni Federica , Pucciarini Lucia , Carotti Andrea , Natalini Serena , Raskildina Gulnara Z. , Sardella Roccaldo , Natalini Benedetto 
Published: August 2018

AbstractChiral ligand‐exchange chromatography is one of the elective strategies for the direct enantioresolution of small chelating compounds: amino acids, diamines, amino alcohols, diols, small peptides, etc. Unlike other methods, the interaction between chiral selector and analyte enantiomers is mediated by a cation, thus producing diastereomeric ternary complexes. Two main approaches are conventionally applied in chiral ligand‐exchange chromatography. The first relies upon chiral stationary phases where the chiral selector is either covalently immobilized or physically adsorbed onto suitable packing materials (coated phases). In the second approach, chiral molecules are added to the eluent, thus generating chiral eluent systems. Among the advantages of chiral ligand‐exchange chromatography, the generation of UV/vis‐active metal complexes, and the use of commercially available or easy‐to‐synthesize chiral selectors, in combination to rather inexpensive achiral columns for coated phases and chiral eluents, are noteworthy. Besides amino acids and amino alcohols, other species have proven suitable for chiral ligand‐exchange chromatography applications. Recently, the use of either chiral ionic liquids or micellar liquid chromatography systems as well as the successful off‐column formation of diastereomeric complexes have expanded the selectivity profiles and application fields. All of these issues are touched in the review, shedding light to the contributions appeared in the last decade.
Characterization of balls by generalized Riesz energy
Authors: O'Hara Jun 
Published: August 2018

AbstractWe show that balls, circles and 2‐spheres can be identified by generalized Riesz energy among compact submanifolds of the Euclidean space that are either closed or with codimension 0, where the Riesz energy is defined as the double integral of some power of the distance between pairs of points. As a consequence, we obtain the identification by the interpoint distance distribution.
Free jejunal flap transfer containing multiple vascular pedicles for pharyngoesophageal reconstruction in conjunction with anterior mediastinal tracheostomy
Authors: Kubo Tateki , Kurita Tomoyuki , Tashima Hiroki , Seike Shien , Fujii Takashi , Yano Masahiko , Yamasaki Makoto , Doki Yuichiro , Hosokawa Ko 
Published: August 2018

AbstractBackgroundWhen pharyngoesophagectomy is performed in conjunction with anterior mediastinal tracheostomy, reconstructing both the trachea and alimentary tract is extremely difficult. We developed a novel 1‐stage reconstructive procedure using a single free jejunal flap containing multiple vascular pedicles to decrease postoperative morbidity and mortality. Free jejunal flap transfer with multiple vascular pedicles could offer a viable option for reducing associated life‐threatening complications.MethodsWe performed a retrospective review of 34 patients who underwent free jejunal flap transfer with multiple vascular pedicles in anterior mediastinal tracheostomy and pharyngoesophagectomy due to lesions involving both the airway and esophagus. In all cases, 1‐stage reconstruction of the digestive tract and trachea was performed. Technical details and outcomes were analyzed.ResultsAll 34 jejunal flaps (100%) survived. Major morbidity classified as Clavien–Dindo grades III and IV occurred in 10 (29.4%) and 0 (0%) patients, respectively during hospitalization. With regard to common complications, anastomotic leakage from transferred jejunal flaps and surgical site infections occurred in 0 (0%) and 7 (20.6%) patients, respectively. Five (14.7%) patients experienced tracheal stoma dehiscence. Donor site morbidity was observed in 2 (5.9%) patients. The overall in‐hospital mortality rate was 2.9%.ConclusionsOur 1‐stage reconstruction procedure achieved low morbidity and low mortality rates following anterior mediastinal tracheostomy and pharyngoesophagectomy. Only 1 jejunal flap transfer is needed to simultaneously reconstruct the trachea and alimentary tract in a safe and reliable manner with this procedure.
Porphyrinic Ionic Liquid Dyes: Synthesis and Characterization
Authors: Li Kai , Titi Hatem M. , Berton Paula , Rogers Robin D. 
Published: August 2018

AbstractFour porphyrinic ionic liquids and four higher melting salts (>100 °C) were synthesized as potential photosensitizers from highly symmetric porphyrins by introducing alkyl chains and exchanging anions to tune their solubility and singlet oxygen generation capability. Among the synthesized compounds was 5,10,15,20‐tetra(4‐dodecylpyridinum)porphyrin tetrakis‐bis(trifluoromethylsulfonyl)‐amide, a room‐temperature ionic liquid that could be crystallized as a solvate with nitrobenzene.
Crystalline structure and phase transition of syndiotactic styrene‐based copolymers
Authors: Naga Naofumi , Sakurai Takaaki , Hashimoto Taku , Noguchi Keiichi 
Published: August 2018

AbstractCrystalline structure and phase transition of clathrate phase of syndiotactic poly[styrene‐co‐(p‐R‐styrene)] (St/RSt; R = CH3 (Me), tert‐butyl (Bu), HO), prepared from solutions, have been investigated with wide‐angle X‐ray diffraction (WAXD) and differential scanning calorimetry. The copolymers containing less than 67.2 mol% of MeSt or 9.4 mol% of BuSt formed δ phase crystallized from toluene solution. The Bragg distance of 010 and reflections of the St/MeSt copolymer slightly increased with increasing of the MeSt content over 10 mol%. The St/HOSt copolymer containing 16.1 mol% of HOSt crystallized from dioxane solution also formed δ phase crystal. The orientation of the crystalline phase of the copolymers in films, which were prepared by cast‐crystallization from o‐xylene or dioxane solution, was evaluated using WAXD. The degrees of orientation were almost independent of RSt content in the copolymers. Phase transition from the δ phase crystal to the α or γ phase crystal of the copolymers in the heating process was observed using WAXD. The copolymers containing less than 14.8 mol% of MeSt or 8.4 mol% of BuSt showed a transition from the δ phase to the γ phase at more than 150 °C. Crystallinity of St/BuSt in the γ phase was lower than that in the δ phase. © 2018 Society of Chemical Industry
Heat resistant and transparent organic–inorganic hybrid materials composed of N‐allylmaleimide copolymer and random‐type SH‐modified silsesquioxane
Authors: Oban Ryohei , Matsukawa Kimihiro , Matsumoto Akikazu 
Published: August 2018

ABSTRACTA thermally stable and transparent copolymer (PAED) composed of N‐allylmaleimide, N‐(2‐ethylhexyl)maleimide, and diisobutylene as the repeating units was produced by radical copolymerization in the presence of an azo initiator in chloroform at 60 °C. The thiol–ene reaction between the allyl groups included in the side chain of PAED and the mercapto groups (SH) included in a random‐type SH‐modified silsesquioxane (SQ) as the crosslinker provided PAED–SQ hybrid materials upon heating. The reaction process for this thermal curing was monitored from the intensity changes of characteristic peaks by IR spectroscopy as well as the gravimetric determination of the isolated insoluble fractions. The thermal, optical, and mechanical properties of the hybrids were investigated. The onset and maximum decomposition temperatures were 322–369 °C and 399–431 °C, respectively. The weight residue at 800 °C was 16–40 wt%, which depended on the amount of the SQ content in the feed. These organic–inorganic hybrid materials were highly transparent and exhibited refractive index of 1.522–1.524 and Abbe number of 40.0–45.8. The tensile test and dynamic mechanical analyses were also carried out to investigate the mechanical properties and the network structures of the hybrids. The addition of triallylisocyanurate (TAIC) to the curing system efficiently improved the conversion of the allyl and SH, leading to the more dense network structure and the higher strength and hardness of the cured hybrids. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018, 56, 2294–2302
Digital health interventions to help living with cancer: A systematic review of participants' engagement and psychosocial effects
Authors: Escriva Boulley Géraldine , Leroy Tanguy , Bernetière Camille , Paquienseguy Françoise , Desfriches‐Doria Orélie , Préau Marie 
Published: August 2018

AbstractObjectiveDigital health interventions (DI) open the possibility for cancer patients and survivors to manage the disease and its side effects when they return home after treatment. This study aims to highlight the components of DI, investigate patient engagement with DI, and explore the effects of DI on psychosocial variables.MethodsIn September 2017, we performed a systematic review of studies focusing on DI which target cancer patients or survivors.ResultsA total of 29 articles (24 studies) were reviewed. There was considerable heterogeneity in study methods, in outcome definitions, in measures for engagement with DI and in psychosocial variables assessed. Results from the studies showed a high level of engagement. Self‐efficacy, psychological symptoms, and quality of life were the most commonly assessed psychosocial variables. However, results for the effect of DI on psychosocial variables were inconsistent. Regarding pain management, results were in line with what one would expect.ConclusionsThe present review showed that despite the heterogeneity in the studies assessed and inconsistent results, DI may constitute an excellent means to help cancer patients and survivors cope better with the disease and with treatment side effects, as they can improve self‐management and wellbeing. In order to acquire a greater understanding of the mechanisms underlying cancer patients'/survivors' psychological and behavioral changes in terms of adopting DI, direct comparison between studies is needed. However, this can only come about if methodological and conceptual standardization of DI is implemented.
Fenoxaprop‐ethyl affects mouse oocyte quality and the underlying mechanisms
Authors: He Ya‐Ting , Yang Lei‐Lei , Zhao Yong , Shen Wei , Yin Shen , Sun Qing‐Yuan 
Published: August 2018

ABSTRACTBACKGROUNDFenoxaprop‐ethyl (FE) is an active ingredient of commercially available herbicide formulations. Its overuse has caused much damage to the environment, livestock breeding, agricultural crops and humans. However, little is known about the effects of FE exposure on female reproductive health and the mechanisms underlying those effects. In this study, we investigated the toxic effects of FE on oocyte quality and their underlying mechanisms in mice fed a diet containing FE.RESULTSOvary weight and numbers of oocytes were reduced in FE‐treated mice. Moreover, oocyte quality was seriously impaired, as shown by the reduced rate of first polar body extrusion and fertilization ability in vivo. In FE‐treated mice, oocytes presented reduced actin expression and abnormal meiotic spindle morphology, which indicate that cytoskeletal integrality is disrupted. Also, FE induced mitochondrial dysfunction, reflected by the accumulation of reactive oxygen species (ROS), apoptosis and autophagy, as revealed by fluorescent staining analysis and real‐time polymerase chain reaction (qPCR). Finally, FE led to changes in epigenetic modifications such as histone H3K27me3 and H3K9me2 in oocytes.CONCLUSIONSOur results indicate that FE has adverse effects on oocyte quality as assessed by maturation and fertilization potential, due to disrupted cytoskeletal integrality, and mitochondrial dysfunction leading to ROS accumulation, apoptosis and autophagy. © 2018 Society of Chemical Industry
Three‐Component Domino Reaction Promoted by Solid Acid: An Efficient Strategy for Synthesis of Pyrano[2,3–d]pyrimidine Derivatives
Authors: Xia Qiqi , Li Chunmei , Zhang Yaohong , Qi Chenze , Zhang Furen 
Published: August 2018

AbstractA series of poly‐substituted pyrano[2,3–d]pyrimidine derivatives have been synthesized using solid acid as catalyst in water. The poly‐substituted pyrano[2,3–d]pyrimidines are important structural motifs in organic and biological research. The present procedure shows many attractive advantages, such as the operational simplicity, highly efficiency and recyclability of heterogeneous catalyst, and highly yields of desired products. A probable mechanism was proposed for accounting the domino reaction.
DFT Study of Skutterudite CoSb3 and In0.2Co4Sb12 Thermoelectric Heterostructures with 2D–WSe2
Authors: Kiarii Ephraim Muriithi , Govender Krishna Kuben , Mamo Messai Adenew , Govender Penny Poomani 
Published: August 2018

AbstractRecently, two–dimensional WSe2 transition–metal dichalcogenides have been used for novel electronic devices. However, its influence on the electronic and optical properties of thermoelectric Skutterudite CoSb3 and In0.2Co4Sb12 is unknown. Despite the increased potential of energy conversion obtained by doping CoSb3 with indium, further theoretical study is necessary to understand the origin of this enhancement. Heterostructures of hybrid WSe2/CoSb3 and WSe2/In0.2Co4Sb12 are investigated in this study using a density functional theory calculation. The electronic structure, energy, geometry optimisation and optical properties are analysed for the individual components in the heterostructure. The obtained results show that pure CoSb3 has a bandgap of 0.456 eV, and In0.2Co4Sb12 has a zero bandgap, while the calculated bandgap for WSe2 is found to be 1.482 eV. The heterostructures show an exceptional absorption in the infrared region where the heat energy mainly dominates. The charge transfer study indicates a built–in potential at the interface, which ensures easy separation of charge generated carriers and thus, improved the thermoelectric performance.
Expanding the Scope of Functionalized Small Nonprotein Components for Holoabzyme 27C1
Authors: Ishikawa Fumihiro , Shirahashi Masato , Hayakawa Hiroshi , Tanabe Genzoh , Tsumuraya Takeshi , Fujii Ikuo 
Published: August 2018

AbstractThe creation of artificial enzymes that achieve high selectivity, and turnovers equivalent to natural enzymes remains a challenging aspect of biocatalyst research. The design of new catalytic proteins presents a straightforward test of our understanding of enzyme catalysis. The holoabzyme 27C1 possesses binding pockets for substrates, as well as for a large variety of functionalized small nonprotein components. Site‐directed chemical mutations have optimized the β‐elimination activity of antibody 27C1, resulting in a 106 fold rate enhancement. In this study, we incorporate synthetic catalytic components with different steric properties into the binding site, and investigate the substrate scope of the 27C1‐catalyzed β‐elimination reaction. Our results indicate that the flexibility and tunability of the binding pocket toward synthetic small molecules may enable incorporation of newly devised components, and thus, introduce novel reactivities.
A multivariate metabolic imaging marker for behavioral variant frontotemporal dementia
Authors: Nazem Amir , Tang Chris C. , Spetsieris Phoebe , Dresel Christian , Gordon Marc L. , Diehl‐Schmid Janine , Grimmer Timo , Yakushev Igor , Mattis Paul J. , Ma Yilong , Dhawan Vijay , Eidelberg David ,   Alzheimer's Disease Neuroimaging Initiative
Published: August 2018

AbstractIntroductionThe heterogeneity of behavioral variant frontotemporal dementia (bvFTD) calls for multivariate imaging biomarkers.MethodsWe studied a total of 148 dementia patients from the Feinstein Institute (Center‐A: 25 bvFTD and 10 Alzheimer's disease), Technical University of Munich (Center‐B: 44 bvFTD and 29 FTD language variants), and Alzheimer's Disease Neuroimaging Initiative (40 Alzheimer's disease subjects). To identify the covariance pattern of bvFTD (behavioral variant frontotemporal dementia–related pattern [bFDRP]), we applied principal component analysis to combined 18F‐fluorodeoxyglucose–positron emission tomography scans from bvFTD and healthy subjects. The phenotypic specificity and clinical correlates of bFDRP expression were assessed in independent testing sets.ResultsThe bFDRP was identified in Center‐A data (24.1% of subject × voxel variance; P < .001), reproduced in Center‐B data (P < .001), and independently validated using combined testing data (receiver operating characteristics–area under the curve = 0.97; P < .0001). The expression of bFDRP was specifically elevated in bvFTD patients (P < .001) and was significantly higher at more advanced disease stages (P = .035:duration; P < .01:severity).DiscussionThe bFDRP can be used as a quantitative imaging marker to gauge the underlying disease process and aid in the differential diagnosis of bvFTD.