bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adaptive compensation using long short‐term memory networks for improved control performance in real‐time hybrid simulation
Authors: Lai Zhenfeng , Liu Yanhui , Zhai Zhipeng , Zhang Jiajun 
Published: November 2024

AbstractReal‐time hybrid simulation (RTHS) divides structural systems into numerical and experimental substructures, providing a cost‐effective solution for analyzing structural systems, especially those that are large or complex. However, the actuation systems between these substructures inevitably introduce delays, affecting the stability and accuracy of RTHS. To address this issue, this study proposes an adaptive compensation method based on a conditional adaptive time series (CATS) compensator and a long short‐term memory (LSTM) network, termed CATS‐LSTM. The LSTM model predicts actuator responses for parameter estimation and calculates prediction errors, improving control performance and reducing delays. The effectiveness of the proposed CATS‐LSTM method and the accuracy of the LSTM prediction are validated through a series of simulations and experiments. The results indicate that the proposed CATS‐LSTM method outperforms both the CATS and phase lead (PL) methods. Compared to the CATS method, the proposed method reduces the maximum delay, root mean square error, and peak error by 3 ms, 3.66%, and 4.78%, respectively, while achieving reductions of 12 ms, 8.4%, and 10.05%, compared to the PL method. Furthermore, the CATS‐LSTM method is significantly less sensitive to initial parameter estimates, compared to the CATS method, enhancing robustness and mitigating the effects of inaccurate or varying initial parameter estimates.
Centromeres are hotspots for chromosomal inversions and breeding traits in mango
Authors: Wilkinson Melanie J. , McLay Kathleen , Kainer David , Elphinstone Cassandra , Dillon Natalie L. , Webb Matthew , Wijesundara Upendra K. , Ali Asjad , Bally Ian S. E. , Munyengwa Norman , Furtado Agnelo , Henry Robert J. , Hardner Craig M. , Ortiz‐Barrientos Daniel 
Published: November 2024

Summary
Chromosomal inversions can preserve combinations of favorable alleles by suppressing recombination. Simultaneously, they reduce the effectiveness of purifying selection enabling deleterious alleles to accumulate.
This study explores how areas of low recombination, including centromeric regions and chromosomal inversions, contribute to the accumulation of deleterious and favorable loci in 225 Mangifera indica genomes from the Australian Mango Breeding Program.
Here, we identify 17 chromosomal inversions that cover 7.7% (29.7 Mb) of the M. indica genome: eight pericentric (inversion includes the centromere) and nine paracentric (inversion is on one arm of the chromosome). Our results show that these large pericentric inversions are accumulating deleterious loci, while the paracentric inversions show deleterious levels above and below the genome wide average. We find that despite their deleterious load, chromosomal inversions contain small effect loci linked to variation in crucial breeding traits.
These results indicate that chromosomal inversions have likely facilitated the evolution of key mango breeding traits. Our study has important implications for selective breeding of favorable combinations of alleles in regions of low recombination.
Co‐production of insights for place‐based approaches to revitalise te taiao in Aotearoa New Zealand
Authors: Turner James A. , Stokes Simon , Te Hurinui Jones Richard , Hemi Murray , Collins Heather , Vannier Clémence , Burkitt Lucy , Bradley Clare , Doehring Katharina , Macintosh Katrina A. , Young Justine , Roskruge Nick , Perry‐Smith Piripi , Kahukura Iosefa Renee , Walker Ngarangi , Young Fiona , Bell Amanda , McDermott Alan , Wood Charlotte 
Published: November 2024

AbstractCommunities across Aotearoa New Zealand are collaborating to reverse ecological decline, but little attention has been given to understanding the deeper relationship required with our physical and socio‐cultural landscapes. We used knowledge co‐production to develop 11 insights to support place‐based strategies that nurture a collective responsibility to revitalise both people and place. Twenty‐five subject matter experts across communities, government, industry and research drew from their collective expertise and the review of 63 local‐to‐global case study examples of farm‐to‐community‐scale place‐based approaches. A key output from this work is an Aotearoa New Zealand framework that diagrammatically represents the interdisciplinary nature of the 11 insights.
Electrophysiological Characteristics and Mechanism of His‐Bundle Pacing Guided by Electrocardiograms in Uninterrupted Real‐Time Monitoring Technique
Authors: Zhong Jinyan , Jiang Longfu , Zhang Yuelin , Zheng Nan , Li Hengdong 
Published: November 2024

ABSTRACTBackgroundHis‐bundle pacing (HBP) is a pacing mode that provides near‐physiological pacing and has more advantages over standard right ventricle (RV) septum pacing in positive clinical results. However, traditional HBP cannot accurately and stably place the lead tip into the His‐Purkinje system. Hence, this study aimed to establish a novel strategy for HBP to strike a balance between an excellent pacing threshold and minor injuries to the conduction system.MethodsHBP, using continuous and real‐time monitoring of unipolar His‐bundle (HB) electrograms along with electrocardiograms, was performed in 29 consecutive atrial fibrillation patients. We analyzed the unipolar HB intracardiac electrogram (EGM) and electrophysiological characteristics during HBP using John Jiang's connecting cable and an electrophysiology recording system. All patients were followed up for 12 months.ResultsOf the 29 patients, 28 (96.55%) successfully received HBP. Twenty‐one (75%) patients were confirmed to have the negative deflection of His potential with a negative amplitude of ≥ 0.1 mV in HB EGM. The subgroup with a deep negative deflection was recorded with an HBP threshold (0.71 ± 0.41 V), significantly lower than those thresholds with no deep negative deflection (1.83 ± 0.76 V) (p < 0.05). The selective HBP rate was significantly different between the two groups: 20 (95.24%) in the deep negative deflection group and three (42.86%) in the non‐deep negative deflection group (p < 0.05); five (17.24%) patients presented right bundle branch block (RBBB) during the lead placement.ConclusionsThis study supports the safety and feasibility of using an uninterrupted real‐time monitoring technique for HBP. An uninterrupted real‐time monitoring technique can guide the accurate placement of the HB lead and may provide a balance between an excellent pacing threshold and minor injury to the conduction system.
Endogenous Tissue Inhibitor of Metalloproteinase‐2 Levels Are Associated With High‐Quality Neat Semen but Unrelated to Sperm Cryoresistance in Bulls
Authors: Pande M. , Kumar S. , Tyagi S. , Sirohi A. S. , Chand N. , Soni Y. K. , Mahajan S. , Saha S. , Sharma A. , Sarika  , Rajoriya J. S. , Anjali  , Mohanty A. K. 
Published: November 2024

ABSTRACTTissue Inhibitor of Metalloproteinase‐2 (TIMP‐2) is part of the tissue inhibitors of the metalloproteinases (TIMPs) family. Its primary function is to regulate the activity of matrix metalloproteinases (MMPs) across various tissues, including those of the reproductive system. This study aimed to quantify the natural levels of TIMP‐2 in seminal plasma (SP) and sperm membrane (SM) of bulls, explore potential associations between TIMP‐2 levels and semen quality parameters, and examine the relationship between TIMP‐2 levels and sperm cryoresistance in bulls. Thirty semen samples from Frieswal breeding bulls were categorized into two groups based on their initial progressive motility (IPM): Good (IPM ≥ 70%; n = 21) and Poor (IPM ≤ 40%; n = 9). The samples were evaluated for their quality parameters at the fresh stage, and TIMP‐2 levels were measured in SP and SM using a bovine‐specific ELISA kit. Following cryopreservation of Good samples (n = 21), post‐thaw motility (PTM) was used to further classify samples into Freezeable (PTM ≥ 50%; n = 14) and Non‐Freezable (PTM < 50%; n = 7) groups. In frozen–thawed samples, sperm attributes, kinetics, and functional parameters were assessed, and the results were correlated with retrospective TIMP‐2 levels of SP/SM. Our study revealed that the quantified levels of TIMP‐2 ranged from 100.27 to 535.95 ng/L in SP and from 0 to 115.78 ng/10 million spermatozoa in SM. TIMP‐2 levels in both SP and SM were significantly higher in Good ejaculates compared to Poor ejaculates (p < 0.01). Furthermore, total TIMP‐2 levels in the SP/SM of semen samples from bulls showed a positive correlation with fresh semen attributes. However, SP/SM TIMP‐2 levels in the Freezeable group did not show any significant differences compared to the Non‐Freezable group in post‐thaw semen quality attributes, kinetic parameters, and functional tests, except for a significant positive correlation (r = 0.530, p < 0.05) between sperm DNA integrity and SP‐TIMP‐2 levels. In conclusion, the findings suggested that TIMP‐2 can be a positive regulator of semen quality at the neat stage. However, when it comes to the resilience of sperm to cryopreservation, the levels of TIMP‐2 do not seem to exert any significant influence in breeding bulls.
The Nexus Between Financial Literacy and Saving Performance: Implications for Creating Self‐Financing Society
Authors: Duguma Girma Jirata , Han Jiqin 
Published: November 2024

ABSTRACTMaking informed and effective savings decisions requires adequate knowledge and skills about saving products. This knowledge and skills are acquired through financial literacy (FL) training. Despite the existence of various local financial institutions and their efforts to encourage saving mobilization, domestic savings in many developing countries remain low due to low levels of FL. Using a nonrandomized, quasi‐experimental design method, with a sample of 328 saving and credit cooperatives (SACCOs) from Ethiopia, we investigated whether SACCOs providing FL for their education and Savings Committee members report improved saving performance than their counterparts not offering FL. We used administrative data and conducted our analysis at the institutional level. Our result from a combination of difference‐in‐difference and propensity score matching (DiD‐PSM) estimations reveals that FL training plays a decisive role in boosting SACCOs' saving performance. The DiD‐PSM result further shows, compared to controlled SACCOs, treated SACCOs have been successful in acquiring new net saver members and encouraging current members to increase their deposits. Besides, the implications of our findings for financial self‐reliance are discussed. To improve saving performance, policy initiatives promoting FL training in SACCOs are required.
Propagation Dynamics in Time‐Periodic Reaction–Diffusion Systems with Network Structures
Authors: Deng Dong , Li Wan‐Tong , Ruan Shigui , Zhang Liang 
Published: November 2024

ABSTRACTThe main purpose of this paper is to study the propagation dynamics for a class of time‐periodic reaction–diffusion systems with network structures. In the first part, by using the persistence theory, we obtain threshold results for the extinction and uniform persistence of the corresponding periodic ordinary differential system. The second part is concerned with the asymptotic speed of spread and traveling wave solutions. The uniform boundedness of solutions is proved by employing the refined high‐dimensional local ‐estimate and abstract periodic evolution theories and the spreading properties of the corresponding solutions are established. We also prove the existence of the critical periodic traveling wave with wave speed by using a delicate limitation argument. Finally, these results are applied to a multistage epidemiological model.
Exploring Peak Concentric Force and Zero Velocity Synchronization in the Drop Jump
Authors: Hook Arlo , Stephens Jessica , Mason Billy , Warmenhoven John , Ball Nick 
Published: November 2024

ABSTRACTThe application of force is a key aspect of performance during athletic activities. In jumping, the timing and magnitude of force application are important performance factors. The relative timing of forces has only been investigated in the countermovement jump. This study aimed to explore if the synchronization of peak concentric force with the instance of zero velocity during a drop jump impacted performance and examine the relationship of force–time curve shape to performance. Sixty‐six state‐level athletes (24 males and 42 females) completed drop jumps from a 30 cm box onto dual force plates. The jump with the highest reactive strength index (RSI) score was taken for analysis and classified as synchronous or asynchronous based on the relative timing of peak concentric force and zero velocity. RSI and other force–time variables were compared between groups, and functional principal component analysis (fPCA) was performed on the force–time curves, which were used to perform functional principal component regression (fPCR). Synchronous jumpers exhibited greater RSI scores and shorter contact times compared to asynchronous jumpers. Performance differences were largely driven by improved concentric kinetics, which the fPCR model revealed to have the greatest influence on RSI. Sex was also found to be a significant factor for RSI in the fPCR model. fPCA revealed that greater force application preceding and throughout the amortization phase was positively associated with RSI. The timing of peak concentric force and the shape of the force–time curve are key factors for drop jump performance, and these concepts should be investigated further in other athletic activities.
Manure‐biochar blends effectively reduce nutrient leaching and increase water retention in a sandy, agricultural soil: Insights from a field experiment
Authors: Lebrun Manhattan , Aguinaga Maria , Zahid Zubda , Šimek Pavel , Ouředníček Petr , Klápště Petr , Száková Jiřina , Bímová Kateřina Berchová , Jačka Lukáš , Beesley Luke , Punčochář Jan , Trakal Lukáš 
Published: November 2024

AbstractOrganic amendments are commonly applied singularly to soils to improve physical, biological and chemical properties, but their combination may be even more advantageous than when applied alone. In this study manure was applied singularly and in combination with biochar (90:10 and 50:50 ratios) to a drought prone agricultural Regosol in a field evaluation. Samples were collected twice a year for 2 years and subjected to testing for moisture retention, nutrient status and microbial activity whilst weed growth was monitored by drone. Substantial seasonal variability in all parameters measured was observed, though all amendments increased actual soil moisture content between 18 and 41% initially; without the addition of biochar (i.e., manure alone) this reverted back to reduced moisture content towards the second year of sampling. None of the tested amendment combinations significantly affected soil‐saturated hydraulic conductivity. Cation exchange capacity decreased as a result of manure addition alone, the addition of 10% biochar and 50% biochar increased this significantly (23%–54% increase). Though microbial biomass and enzyme soil health indicators showed no decisive changes as a result of amendment application, and plant biomass was variable by ground sampling, drone imagery proved that plant heights and health were generally increased as a result of biochar addition to manure, compared with manured soil alone. In summary, despite much field seasonal variability limiting the interpretation of the data, this study nonetheless demonstrates a useful maintenance of improved soil moisture achieved by adding biochar together with manure to a drought‐prone soil agricultural soil.
An unusual case of reagent interference in transfusion medicine workup: Pan reactive indirect antiglobulin test caused by commercial saline solution
Authors: Pedersen Martin Tøffner , Bach‐Hansen Helle , Rasmussen Kristina Fruerlund , Yazer Mark H. , Sprogøe Ulrik 
Published: November 2024

AbstractBackgroundAt the regional transfusion service in the Region of Southern Denmark, serological investigations are primarily carried out using column agglutination techniques. This case study examines an unusual instance of reagent interference in pretransfusion testing using column agglutination at the Hospital of Southern Denmark, Aabenraa.Case PresentationA 72‐year‐old male patient presented for pretransfusion testing prior to hernia surgery. He typed as O RhD negative without discrepancies, but the antibody screen showed weakly positive reactions. Routine investigations showed discrepancies, leading to further investigations.MethodsVarious serological tests were performed using in‐house and commercial red test cells suspended in different suspension media and with different column agglutination cards and cassettes. Further investigations included washing of test cells, testing alternative saline solutions, varying incubation temperatures, testing without antihuman‐globulin, and applying proteolytic enzymes.ResultsReactivity was present with red cells suspended in ID‐CellStab (BioRad) but not in Red Cell Diluent (Quidel‐Ortho). Reactivity was abolished by using trypsin‐treated cells, indicating either the presence of an antibody reacting with—or unspecific agglutination depending on—a trypsin‐sensitive protein, in both cases enhanced by ID‐CellStab.ConclusionThis case highlights the importance of recognising reagent‐dependent reactivity in serological testing. Adjustments to the suspension media resolved the incompatibility. Immunohematology laboratories should consider potential reagent interference when unexpected agglutination occurs.
Antimicrobial Resistance and Zoonotic Potential of Nontyphoidal Salmonella From Household Dogs
Authors: Kenney Sophia M. , M'ikanatha Nkuchia M. , Ganda Erika 
Published: November 2024

ABSTRACTBackgroundCompanion animals, like household dogs, are an overlooked transmission point for zoonotic pathogens such as nontyphoidal Salmonella (NTS). Given the proximity of dogs to humans and the use of critically important antibiotics in companion animal medicine, household dogs represent a risk for the spread of antimicrobial‐resistant (AMR) Salmonella.Methods and ResultsTo this end, we aimed to leverage existing biosurveillance infrastructure to investigate AMR and the zoonotic potential of NTS isolated from dogs and humans. We identified all NTS strains isolated from domestic dogs via the Veterinary Laboratory Investigation and Response Network between May 2017 and March 2023 (N = 87), and spatiotemporally matched strains isolated from humans in the NCBI Pathogen Isolate Browser (N = 77). These 164 strains, collected from 17 states in the United States, formed the basis of our analysis. Strains isolated from dogs comprised diverse serovars, with most being clinically relevant to human health. All strains possessed AMR determinants for drug classes deemed critically or highly important by the World Health Organization. We identified sixteen NTS isolates from humans closely related to ≥1 of six dog‐associated strains.ConclusionsCollectively, our data emphasize the importance of antimicrobial stewardship and sustained biosurveillance beyond human‐ and agriculture‐associated veterinary medicine, using a One‐Health framework that accounts for all transmission points including companion animals.
Integrating Motion Intention and Impedance Control in Teleoperated Robotic Rehabilitation for Upper Extremity Disorders
Authors: Banzon Angelo-Jose , Wang Emily , Luo Yue , Jin Li , Jiang Lin 
Published: November 2024

Abstract
Due to the global pandemic in 2020, rehabilitation services had to adapt to virtual care to meet the needs of patients with a diversity of upper extremity disorders and injuries, from simple fingertip injuries to replanted extremities, while mitigating the spread of COVID-19. For patients who require occupational therapy in their rehabilitation, teleoperated robotic care can fulfill this need. Moreover, some clinical studies show that incorporating the active intention of patients into rehabilitation training enhances the effectiveness of therapies. This research aims to develop a bilateral impedance controller with a Franka Emika 7DOF (degree-of-freedom) articulated robot using matlab, facilitating upper limb occupational therapy. Through this setup, the Franka robot will lead patients through various therapeutic exercises based on their motion intention, such as a pick-and-place exercise. The exercises' efficacy is assessed through evaluations of torque, muscle strength, and jerking performance. During patients' rehabilitation exercises with the Franka robot, we anticipate observing decreased muscle activity alongside a smooth, assist-as-needed (AAN) trajectory. This method will allow a patient to perform complex movements essential for daily activities quicker than traditional occupational therapy.
Right Heart Recovery Post Lung Transplant With COVID‐19‐Related Acute Respiratory Distress Syndrome
Authors: Arunachalam Ambalavanan , Toyoda Takahide , Nayak Tanvi , Jankowski Madeline , Cerier Emily Jeong , Kaihou Taisuke , Joudi Anthony , Mohsin Suror , Yeldandi Anjana , Venkata Subramani Mrinalini , Myers Catherine , Tomic Rade , Bharat Ankit , Maganti Kameswari , Kurihara Chitaru 
Published: November 2024

Background: Right heart remodeling is noted in patients with severe COVID‐19‐associated acute respiratory distress syndrome (ARDS). There is limited information regarding right heart recovery following lung transplantation in this cohort.Methods: Retrospective review of institutional transplant database from June 2020 to June 2022 was performed at Northwestern University in Chicago, Illinois. Demographic, laboratory, histopathologic, lung transplant outcomes, and pre‐ and postoperative echocardiographic data were recorded and analyzed.Results: Of the 42 patients who underwent lung transplantation for COVID‐19‐related ARDS, 6 patients were excluded due to having either a single‐lung transplant (n = 2), lobar transplant (n = 1), or dual‐organ transplant (n = 1) or for missing postoperative TTE data (n = 2) and 36 were included in the study; there were no 90‐day deaths, and the 1‐year survival rate was 88.8%. Intraoperative hemodynamics data showed a mean pulmonary artery pressure of 49 ± 23 mm Hg. Preoperative echocardiography was evaluated at a median of 15.5 (10–34.3) (IQR) days preoperatively and 140 (108–201) days (IQR) postoperatively. RV size grade improved from an average of 1.7 ± 0.85 to 1.3 ± 0.6 (p < 0.05), while RV function improved from an average of 2.2 ± 1.2 to 1 ± 1 (p < 0.05). There was a reduction in RVSP from 46.5 ± 18 mmHg to 30.1 ± 7.8 mmHg (p < 0.05) and RV free wall strain showed improvement from −13.9 ± 6.1% to −18.5 ± 5.4% (p < 0.05).Conclusions: The results showed that the RV size and systolic function demonstrate improvement with normalization in a relatively short period following lung transplantation for patients with COVID‐19‐associated ARDS.