bluuebunny/crossref_metadata_2025_split huggingface dataset:
Carlos Contreras y la planificación del puerto de Veracruz
Authors: Escudero Alejandrina 
Published: May 2018

En el periodo político llamado maximato, que va de 1929 a 1934, las propuestas de planificación del arquitecto Carlos Contreras fueron introducidas en un programa de Estado ; de ese modo, se aplicaron algunas de las estrategias del urbanismo moderno, entre ellas, se promulgaron legislaciones, se crearon organismos especializados, se usaron sus herramientas, y se adoptaron nociones, tales como la misma planificación, la zonificación y las escalas nacional, regional y urbana.
En ese lapso se prepararon los primeros proyectos para la planifieaciôn de la Republica mexicana, sus ciudades y puertos, en particular Acapulco y Veracruz ; éste se convertiría en el primer puerto de México ; el proyecto lograría mejores facilidades para el movimiento comercial, desarrollaría el turismo y regeneraría las condiciones climatológicas. En su programa, Contreras adoptó la noción de región, que por razones políticas no pudo desarrollar ; el postulado «estudiar antes de planificar» ; la formulación del plano regulador ; y los mosaicos aéreos. Este escrito dará cuenta de cómo, en 1929, se abordó la planificación del Puerto de Veracruz planteada por Contreras, valiéndose de las estrategias del urbanismo moderno.
Adolescence, sexualité et pudeur
Authors: Guiouillier Bertrand 
Published: May 2018

Sous l’impulsion de la puberté, le corps de l’enfant devient pubère, il subit une véritable métamorphose alors que les transformations psychiques apparaissent avec décalage. L’adolescent oscille alors entre un retrait avec une inhibition relationnelle, car il sait que « paraitre c’est comparaitre », selon Eric Fiat, ou au contraire il s’expose sur les réseaux sociaux, on parle alors d’extimité. « La pudeur, c’est l’esprit qui rougit du corps » nous dit Eric Fiat ; elle est fortement remodelisée à l’ère du numérique. Le sexuel n’est jamais très loin mais souvent en arrière-plan dans les rencontres avec les professionnels. S’il est complètement absent, il convient de rechercher les raisons de son refoulement ou de son absence.
La confrérie dans le métier. Spirituel et temporel corporatifs à Paris aux XVII e -XVIII e siècles
Authors: Marraud Mathieu 
Published: May 2018

Les confréries de métier, dans la France moderne, ont cela de particulier qu’elles obligent à penser ensemble les aspects temporels et spirituels de l’économie incorporée. L’exemple des grands corps marchands parisiens apporte une dimension essentielle, qui est un rôle de soutien au service d’un groupe de plus en plus restreint, les notables, et de leurs intérêts à la fois sociaux et économiques. Ainsi, l’existence même de la confrérie en tant que communauté propre, ou que lieu intégrateur pour les maîtres, peut être questionnée. Au fil du XVIII e siècle, la confrérie s’apparente à un poste de dépense maîtrisé par les chefs du métier (en règlement des aumônes et du service divin), ainsi qu’à un processus de monétarisation et de tarification des relations internes. La monarchie pourra d’autant mieux la surveiller, l’inspecter, puis la condamner comme une pratique comptable généralement nocive. La confrérie de métier se dilue alors dans une conception de la puissance publique et temporelle, imposée depuis les règles de la monarchie administrative, annonçant en cela la suppression de l’ordre corporatif tout entier par Turgot en 1776.
Infantile Exotropia and Developmental Delay
Authors: Lueder Gregg T. , Galli Marlo 
Published: April 2018

Purpose:
To evaluate a group of infants with this disorder to determine the long-term outcome of surgery and to assess the need for neurologic evaluations.

Methods:
This interventional case series reviewed the records of infants who underwent surgery for the treatment of exotropia with onset during the first year of life. The preoperative ophthalmic and systemic findings, treatment, and developmental and ophthalmic outcomes were reviewed. Surgery was considered successful if the horizontal deviation was less than 10 prism diopters (PD). Developmental assessments were obtained at each visit.

Results:
Twenty-six patients presented between age 2 and 10 months with exotropia ranging from 20 to 95 PD. Ten (38%) patients had a developmental delay that was recognized at the first visit, 9 of whom had a systemic diagnosis at that time; the other patients remained developmentally normal during a mean follow-up of 7 years. Age at surgery ranged from 4 to 18 months. Surgery was successful in 10 (38%) of 26 patients after 1 surgery and in an additional 13 (50%) of 26 patients after a second surgery.

Conclusions:
In this study, the need for more than 1 surgery was higher in infantile exotropia when compared to other forms of childhood strabismus, but most children achieved good alignment with one or two surgeries. Developmental delay is common in patients with infantile exotropia, but this was usually recognized at the time of the initial evaluation. In the current patients, routine neurologic screening or imaging of these otherwise developmentally normal infants was not required.

[
J Pediatr Ophthalmol Strabismus
. 2018;55(4):225–228.]
A Polêmica do Tratamento Psicanalítico do Autismo: Dimensões Políticas, Sociais e Econômicas
Authors: De Moraes Natália De Andrade , Perrone Claudia Maria 
Published: April 2018

Este estudo problematiza a polêmica do tratamento psicanalítico do autismo, situando a forma como se apresenta atualmente no Brasil. Assumindo a indissociabilidade entre os campos político e clínico, propõe a discussão dos aspectos sociopolíticos e econômicos componentes do problema como via de compreensão contextual do que se apresenta como questão clínica. Nesse sentido, trabalha sobre o modo como os avanços da lógica comportamental testemunham um apagamento da dimensão do sujeito, levando à biologização do humano e à relações de supressão da diferença e do sofrimento, discutindo os efeitos do pensamento neoliberal sobre o campo da saúde, especificamente em relação à psicanálise e ao autismo, de forma a evidenciar a submissão a uma lógica de mercado. Por fim, busca situar o lugar da psicanálise no contexto composto, sinalizando seu movimento de resistência à lógica de disputa incorporada nos debates sobre o tratamento do autismo.
Grounds for dialogue: Intersectionality and superdiversity
Authors: Khazaei Faten 
Published: May 2018

Abstract
This paper investigates the possibility of a fruitful dialogue between intersectionality and superdiversity. It argues that, despite the shortcomings of superdiversity, the complex migration-related configurations it focuses on can enable intersectionality to overcome some of its own challenges by becoming more precise and accurate. To empirically expose the mechanisms through which race-, gender-, and class-based inequalities are reproduced, it is necessary to anchor those mechanisms in a specific time and space – a historical, social, economic, and legal context. Through a case study of institutional responses to domestic violence, the paper demonstrates that superdiversity can help clarify the context in which these responses occur. Finally, by distinguishing between the object of study (the intersectional construction of disadvantage and prejudice) and the object of observation (public institutions where superdiverse situations are created by migration-related configurations), this paper examines a challenging situation for intersectional analysis in the context of Switzerland, a context that opens up to surprising articulations of discrimination and inequality for ‘migrants’ subjects to domestic violence.
Triterpenoids with Cytotoxic Potential from the Leaves of <em>Tridax procumbens</em> L.
Authors: Rai Vaishali , Pai Vinitha Ramanath , Duwal Surya Ram 
Published: April 2018

<p align="left">The anticancer activity of crude extracts of the leaves of <em>Tridax procumbens, </em>against two breast cancer cell lines-MCF-7 (benign) and MDA-MB-231 (metastatic) were investigated and an attempt was made to identify the anticancer principle. The extracts with methanol (TPM), ethanol (TPE) and chloroform (TPC) as solvents were screened for cytotoxicity by MTT assay against MCF-7 cells. The effective extract was further evaluated on MDA-MB-231 cells. Among the three extracts, TPC was effective at an IC<sub>50</sub> value of 136 µg/ml and 129 µg/ml on MCF-7 and MDA-MB-231 cells respectively. Phytochemical analysis of the extract showed the presence of only steroids and terpenoids and their concentration was high (77.4% w/w). HPLC-MS of the chloroform soluble crude extract revealed a major peak (57.59% concentration) at a retention time of 4.78 min and MS data of this peak revealed presence of two fragments of molecular weight 475.80 and 701.80. The compounds were identified to be 3β, 9β-Dihydroxy-18α-oleanan-28-oic acid, a derivative of oleanolic acid and 3β, 28-Bis (cinnamoyl) betulin respectively, both from the triterpenoid family. </p>
Antioxidant activity and green synthesis of selenium nanoparticles using allium sativum extract
Authors: Vyas Jay , Rana Shafkat 
Published: April 2018

<p><strong>Abstract</strong></p><p>The green synthesis of nanoparticles has provided cost effective, environment friendly procedure and raising safe strategies for synthesis of non-materials. In this study we investigated the clove of <em>Allium sataivum</em>, which is used for the synthesis of Selenium nanoparticles. The biosynthesized selenium nanoparticles were characterized by using UV-Visible (UV-VIS) spectrophotometer, Transmission electron microscopy (TEM), Fourier transform spectroscopy (FT-IR) and Energy dispersive X-Ray spectroscopy (EDAX). The selenium nanoparticles synthesized by garlic were observed as hollow and spherical particles in size ranging 7-45nm which is found more stable more than two months. The present study also reports the efficiency of ABTS, DPPH and FRAP assay to estimate the antioxidant potential of selenium nanoparticles which synthesized by garlic extract.</p><p> </p>
Role of Quercetin in chemoprevention against wide range of carcinogens and mutagens
Authors: Shivakumar Savithiri , Tadakaluru Yasodha Lakshmi , Yakkanti Raja Ratna Reddy , Suresh Sannidhi Ranga , Sekhar Pasula Chandra 
Published: April 2018

Quercetin is a ubiquitous plant flavoniod with significant pharmacological and clinical activity. In this study we determined to demonstrate the protective role of quercetin against range of mutagens and carcinogens in a combination of <em>in vitro</em> and <em>in vivo</em> studies via different mechanisms. Quercetin demonstrated significant protective role against sodium azide, benzo(a)pyrene, cyclophosphamide monohydrate, methyl methane sulphonate and etoposide compared to other mutagens. Quercetin is effective in both <em>in vitro</em> and <em>in vivo</em> test conditions and also in the presence as well as in the absence of metabolic activation system (Rat liver S9). Auto oxidation, antioxidant properties, inhibition of pro-mutagens metabolism by CYP1A activity and multiple antimutagenic and adaptive response, mechanisms of quercetin may account for its protective role in cancer prevention. In conclusion, the results clearly indicate that quercetin plays a significant role against mutagens that act by direct DNA binding (form DNA adducts), pro-mutagens and alkylating agents with free radical generation; which could be the rationale for its potent anticancer activity against particular cancer types.
Virtual Screening and ADMET Studies to Identify KSP Inhibitors as Anticancer Therapeutics
Authors: Chelamalla Raadhika , Makula Ajitha 
Published: April 2018

<p>Virtual Screening plays an important role to achieve binding affinity, receptor and library pre-processing, docking, scoring and top scoring hits. Optimization of drug ADME parameters continues to play an important role to ensure that the exposure is sufficient to achieve proof of concept, and ultimately efficacy, safely in clinical trials to address unmet medical need.<strong> </strong>In order to identify potential inhibitors we employed various computational approaches. In this work, we computationally screened and analyzed 60 analogs and further tested their ADME/T profiles.<strong> </strong>Library of the molecules was constructed based upon structural modifications of pyrimidines and indole nucleus. Structural modifications were performed for the series of 4-(3-hydroxyphenyl)-6-methyl-2-oxo-N-substituted[(Z)-(2-oxoindolin-3-ylidene)amino]-3,4-dihydro-1H-pyrimidine-5-carboxamide derivatives in an order to get better binding energies as compared with Ispinseb. The molecules with better (lower) binding energies were subjected to predict ADMET properties. Ten molecules from the series IP1-IP60 were found acceptable with binding energies and pharmacokinetic properties. On the basis of the binding energies and ADMET properties we have identified compound IP2 and IP4 to be the best interacting molecules. The molecules with acceptable ADMET properties and better binding energies were prioritized for synthesis and anticancer evaluation. </p>
Examination of the Effect of Preheating Process on Microtensile Bond Strength in the Cementation of Indirect Restorations
Authors: Görüş Zuhal 
Published: April 2018

Aim: The aim of this study was to investigate the effect of preheating of inlay and onlay restorations prepared from composite materials and using a CAD/CAM device on microtensile bond strength in different structures.
Methodology: In this study, 90 impacted human third molar teeth unaffected by the mouth environment were used. These teeth were divided into 3 groups. MOD inlay cavity preparation was performed on all samples according to the parameters specified. For the first group, restorations were prepared using a CAD/CAM device. For the second group, a fiber-reinforced composite (EverX Posterior, GC, Tokyo, Japan) was used on the bottom of the cavity to simulate dentin structure. Restoration was then completed using the laboratory composite system (Gradia, GC, Tokyo, Japan). For the third group, restorations were completed using the laboratory composite system (Gradia, GC, Tokyo, Japan) alone. Er,Cr:YSGG laser (Fotona Laser AT Fidelis Plus III, Slovenia) was administered on all prepared restorations for surface roughening. In the cementation of the restorations, resin cement was administered with and without preheating. The prepared samples were placed in a microtensile tester, and the sticks were broken off by setting the loading speed at 1 mm/min. The prepared samples were tested for microtensile bond strength (Microtensile Tester, Bisco, Schaumburg, IL, USA). The results obtained in Newtons were divided into the surface area and converted to MPa. The results were recorded as microtensile bond strength values.
Results: There was no statistically significant difference between the groups in terms of the statistical evaluation of the microtensile bond strengths of the samples in which the adhesive cement was pre-heated (P) and not pre-heated (N) during the cementations (p>0.05). There was a statistically significant difference (p<0.05) in terms of the microtensile bond strength values between the groups in which the adhesive cement was pre-heated during the cementation of restorations.
Conclusion: It was observed that exposure of the adhesive cement to preheating in the cementation of the EverX Posterior-based inlays adversely affects the bond strength. It was observed that the preheating process statistically significantly increased the bond strength in the inlays made using the Gradia composite. Preheating of the cement in the cementation of Cerasmart composite inlays produced using the CAD/CAM system did not affect the microtensile bond strength.
Insights on the Nationwide Project in Osteopathic Medical Education and Empathy (POMEE)
Authors: Newton Bruce W. 
Published: April 2018

Abstract
Initial data from the first phase of a nationwide study of cognitive empathy, the Project in Osteopathic Medical Education and Empathy (POMEE), have been gathered. At the beginning of their first year of medical school, more than 6000 osteopathic medical students filled out the Jefferson Scale of Empathy. The POMEE principal investigator and co-investigators—Mohammadreza Hojat, PhD; Leonard H. Calabrese, DO; and Stephen C. Shannon, DO—responded to a series of questions posed by the author pertaining to the importance of POMEE and the impact the findings will have on educating osteopathic medical students. Continued success of this large-scale study will depend on the deans of the 41 participating osteopathic medical schools to continue to encourage student involvement in the study as they progress through their 4 years of undergraduate medical education. Study results will be disseminated via national and international meetings and professional journals.
A medicalização da educação na contramão das diretrizes curriculares nacionais da educação básica
Authors: Ribeiro Maria Izabel Souza 
Published: April 2018

Este artigo apresenta uma reflexão sobre o processo de medicalização, mais especificamente, sobre a medicalização da educação. Com o objetivo de discutir a medicalização da vida escolar como dissonante das Diretrizes Curriculares Nacionais da Educação Básica, realiza uma reflexão na interface entre a educação e a psicologia escolar crítica. Para discutir o processo de medicalização fundamenta-se nas autoras Moysés e Collares (1994, 2010, 2013) e Guarido (2010). Com relação à psicologia escolar e educacional em uma perspectiva crítica baseia-se no pensamento de Patto (2008), Souza (2002) e Machado (2000), referências da área. Com base nos referenciais adotados, o estudo teórico discute a medicalização como um processo que sustenta-se na compreensão naturalizada do ser humano que considera os fatores biológicos e psicológicos como determinantes do comportamento, o que implica na transformação de questões coletivas, resultantes da síntese de múltiplos fatores, em questões individuais de ordem biológica, orgânica ou psíquica exclusivamente. Nesse sentido, na abordagem da temática, realiza a crítica à lógica medicalizante de compreensão dos problemas de escolarização enfrentados pelos estudantes na escola. Na análise da Resolução CNE/CEB nº 4, que define as Diretrizes Curriculares da educação brasileira, aborda as dimensões, princípios e objetivos delimitados no documento para confrontá-los com a lógica da medicalização. A análise apresenta argumentos que demonstram a dissonância entre a medicalização da educação e as Diretrizes Curriculares Nacionais, uma vez que as concepções e práticas medicalizantes promovem a exclusão da riqueza e complexidade das manifestações humanas e por consequência produzem o fracasso escolar.
Educação especial no Brasil: a educação de surdos e os desafios na contemporaneidade
Authors: Moraes Wesley Soares Guedes de 
Published: April 2018

RESUMO
O artigo se refere à pesquisa de Mestrado , em que foi realizado um estudo sobre a educação como possibilidade de emancipação do indivíduo, analisando a inclusão dos alunos surdos e/ou com deficiência auditiva no Colégio Estadual Pandiá Calógeras/SG/RJ, locus do estudo, vinculado à Coordenadoria Metropolitana II da Secretaria de Estado de Educação/SEEDUC-RJ. Os objetivos foram: Identificar o que os professores pensam sobre a inclusão escolar de alunos surdos no Colégio Estadual Pandiá Calógeras/SG/RJ, considerando sua prática docente e atitudes frente à educação inclusiva; avaliar a formação dos professores atuantes com alunos surdos em suas salas de aula em relação ao atendimento educacional às suas necessidades educacionais; caracterizar a atuação da gestão em relação à inclusão de alunos surdos e sua mediação junto aos professores, orientadores pedagógicos e demais profissionais. O estudo foi fundamentado teórico e metodologicamente no pensamento de Theodor Adorno, pensador da Teoria Crítica da Sociedade. Os resultados deste estudo revelaram que a educação inclusiva contribui para o desenvolvimento da reflexão sobre a socialização do aluno surdo junto com colegas ouvintes na escola pública; o desenvolvimento da autonomia dos professores que atuam no Colégio Estadual Pandiá Calógeras/SG/RJ; a capacidade de resistência à educação reduzida à adaptação e à dominação cultural na sociedade de classes na formação para a heteronomia. Tais aspectos possibilitaram caracterizar a inclusão de alunos surdos e/ou com deficiência auditiva no ensino regular, desvelando as contradições sociais e revelando os avanços da educação inclusiva.

Palavras-chave: Educação de Alunos Surdos; Formação de Professores; Inclusão Escolar.
Políticas públicas e Reformas Educacionais no Brasil: enfoque no planejamento educacional no âmbito dos Municípios
Authors: Nogueira Dantas Cátia Verônica , Rios de Jesus Tércio 
Published: April 2018

Este texto discute os desdobramentos das políticas públicas e reformas educacionais que entram em curso a partir de 1990, e que introduzem no cenário brasileiro os princípios de descentralização e municipalização do ensino. Busca-se elucidar os impactos das reformas educacionais no âmbito dos municípios, enfatizando a proposição do poder público municipal criar e gerir seus sistemas públicos de ensino, bem como a importância que o planejamento educacional assume para que essa demanda seja atendida. Diante do “imperativo” de reorganizar e manter seus sistemas de ensino, o poder público municipal tem se deparado com inúmeras dificuldades, dentre essas, a elaboração dos planos municipais de educação. <br>
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<B>Palavras-chave</B>: políticas públicas, descentralização, municipalização, planejamento, plano municipal de educação.<br>
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<B>Abstract</B>: This paper discusses the evolution of public policy and education reform that have b“en incorporated in Brazil since 1990 and have introduced the concept of decentralization and education at the local level. Its aim is to analyze the impact of“education reform at the municipal level by emphazing the importance of local government’s participation in developing and
managing its own educational systems as well as demonstrating the value of educational planning for achieving this goal. When facing the demands of reorganizing and keeping their municipal educational systems, local authorities have dealt with numerous difficulties, including the development of their municipal plan for education. <br>
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<B>Key words</B>: public policy, decentralization, community focus, planning, municipal plan for education
Afinal, para quê Ensinar a Língua Escrita? A formação do cidadão letrado
Authors: Bueno Terzi Sylvia 
Published: April 2018

O artigo apresenta discussão sobre alfabetização de jovens e adultos na perspectiva do letramento crítico, contrapondo-o à alfabetização tradicional, própria do letramento escolar, tomando-se como princípio a compreensão de que um ensino da modalidade escrita da língua prevista para jovens e adultos não escolarizados somente se justifica se o ensino lhes proporcionar um maior conhecimento de si e de seu papel social, entendendo a realidade que os cerca, permitindo-lhes agir sobre ela para transformá-la,constituindose em mais um fator de cidadania e inclusão social. <br>
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<B>Palavras-chave</B>: letramento, alfabetização e educação de jovens e adultos. <br>
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<B>Abstract</B>: This article presents a debate about literacy of young and adult people from the perspective of critical literacy, opposing it to traditional and scholastic literacy, taking as a principle the comprehension that the only vindication of teaching written language to illiterate young and adult people, is to provide them a major knowledge of themselves and of their social role,
understanding the surrounding reality, and affording them to act upon and change this reality, becoming an agent of citizenship and social inclusion. <br>
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<B>Key words</B>: literacy - adult and young people education