bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE EFFECT OF WIDE PUSH-UP EXERCISE AND NARROW PUSH-UP EXERCISE AGAINST STRENGTH, POWER, AND ENDURANCE
Authors: Tamimi Nasiruddin , Mintarto Edy , Widya K. Nining 
Published: January 2019

This study aims to improve the level of physical condition, so it can be known and become an evaluation for the sport that achieves a better achievement later. The application of exercises used to improve physical condition is through wide push-ups and narrow push-ups in students of XI IPA in SMA N 1 Sumberrejo Bojonegoro. The type of research used in this study is quantitative with quasi experimental methods (Quasi Experiment). The design used to group research subjects is Matching-Only Design. In this design there are three groups, namely wide push-up exercise group, narrow push-up exercise group, and one control group. Furthermore, the three groups were given a pretest to determine the initial state is there any difference between the experimental group and the control group. After 8 weeks of practice with frequency 3 times a week, then posttest to the three groups to know the effectiveness of the exercise. In the wide push-up exercise group, there was an increase in strength by an average of 2.65 kg, power of 16.92 Joules, and endurance of 2.9 Times. In the narrow push-up exercise group obtained the results of an increase of 3.65 Kg of power, power of 27.91 Joule, and endurance of 3.65 Times. While in the control group obtained the results of an increase of 0.75 Kg of power, power of 4.39 Joule, and endurance of 0.85 Times.Based on the results of research and discussion as described in the previous chapters, it can be concluded that there is a significant influence on the wide push-up exercises on the increase of strength, power, and endurance, there is a significant influence on the exercise of narrow push-up against increased power, power, and endurance, and there are significant differences in influence between wide push-up and narrow push-up exercises for increased strength, power, and endurance
Keywords: Wide push-up exercise, narrow push-up, strength, power, endurance
THE EFFECT LEG MUSCLE EXPLOSIVE POWER, FLEXIBILITY, HAND EYE COORDINATION AND CONFIDENCE OF SKILL LAY UP SHOOT BASKETBALL
Authors: Candra Oki , Asmawi Moch. , Tangkudung James 
Published: January 2019

The purpose of this research is to obtain information on the direct and indirect influence of leg muscle explosive power, flexibility, hand eye coordination and self confidence in basket lay up shoot skills. The research method used in this research is the type of quantitative research with correlational study approach. Technical analysis using path analysis approach (path analysis). The total population of this research is 41 students, sampling technique by total sampling. Total samples in this research is 41 students who followed extracurricular. The results of this research concluded: (1) leg muscle explosive power directly affect the skills of lay up shoot as 0.408, (2) flexibility direct influence on skills lay up shoot as 0.297, 3) hand eye coordination directly affect the skills of lay up shoot as 0,217, (4) self confidence directly influence to skill of lay up shoot as 0,151, (5) leg muscle explosive power directly influence to self confidence as 0,317, (6) flexibility direct influence to self confident as 0,261, 7) hand eye coordination has a direct effect self confidence as 0.282.
Keywords: leg muscle explosive power, flexibility, hand-eye coordination confidence, lay up shoot, survey
THE EFFECT AT MUSCLE POWER ARM, HAND-EYE COORDINATION, FLEXIBILITY AND SELF CONFIDENCE UPON BADMINTON SMASH SKILL
Authors: Akbari Myrza , Dlis Firmansyah , Widiastuti Widiastuti 
Published: January 2019

This study aims to reveal whether there is effect muscle power arm, hand eye coordination, flexibility and confidence to smash badminton skills, either directly or indirectly. The research was conducted at the Serambi Mekkah University, with a sample consisting of 73 samples were selected from 677. physical education, health and recreation students, serambi mekkah university of Banda Aceh" . The analysis technique used in this research is using path analysis (path analysis), with the aim to identify the direct and indirect effect between variables. The results showed that: (1) Arm muscle power directly effect the confidence of 4.62%, (2) Hand-eye coordination has a direct effect on confidence of 59.29%. (3) Flexibility of the torso indirectly effect the confidence of 92.69%, (4) Arm muscle power indirectly effect badminton smash skills of 66.55%. (5) Eye-hand coordination directly effects badminton smash skills by 8.64%, (6) Flexibility of the torso directly effects badminton smash skills by 10.43%, (7) Confidence directly effects badminton smash skills of 14.90%.

Keywords: Badminton smash skills, muscle power arm, hand- eye coordination, flexibility, confident
RELATIONSHIP OF HEMOGLOBIN CONCENTRATION AND LUNG VITAL CAPACITY WITH MAXIMAL AEROBIC CAPACITY (VO2 MAX) AT INDONESIAN NATIONAL ATHLETES
Authors: Junaidi Junaidi 
Published: January 2019

The objectives of this research are to obtain information the relationship of hemoglobin concentration and lung vital capacity with VO2 max at Indonesian national athletes either separately or together. This study was conducted at Indonesian national athletes by using survey method with regression and correlation techniques analysis. The number of 50 athletes from 550 populations as a sample is selected purposive random sampling, The research findings there are 1). There is a relationship of hemoglobin concentration with VO2 max, equation of regression ,used T test (α= 0,05), tvalue = 10,25, ttable = 2,00, correlation coefficient ; rxy1=0,719 and determinant coefficient (r2) = 0,517, 2). There is a relationship of lung vital capacity with VO2 max, equation of regression , used T test (α= 0,05), tvalue = 7,48, ttable = 2,00, correlation coefficient; rxy2=0,733 and determinant coefficient (r2) = 0,538 , 3). There are a relationship of hemoglobin concentration and lung vital capacity are together with VO2 max, equation of regression , used T test (α= 0,05), tvalue = 87,28, ttable =1,59, correlation coefficient ry1-2 = 0,734 and determinant coefficient(ry1-2) = 0,539

Keywords; Hemoglobin concentration, lung vital capacity and VO2 max
THE INFLUENCE OF EXERCISE METHOD AND REACTIONS TIME TO SKILLS SPRINT 100 METERS
Authors: Henjilito Raffly , Asmawi Moch. , Tangkudung James 
Published: January 2019

The purpose of this research was determine the effect of free variables that the method of exercise and the moderator variable reaction time of the dependent variable of 100 meters. The research was done by using experimental method. Target population (research population) are male student of physical education, health and recreation islamic university of riau 2016/2017 123 people. Sampling was done by purposive sampling technique. The hypothesis is 1) difference between group of interval training method (A1) with group of continuous training method (A2) equal to 0,0245 < 0,05, mean h0 rejected. 2) The difference between group of interval training method (A1) and group of mixed exercise method (A3), value = 0,0015 < 0,05, means h0 rejected. 3) The difference between the continuous training method group (A2) and the mixed exercise method group (A3), worth = 0.1345 > 0.05, means h0 received. 4) The interaction effect of fo (AB) worth = 0,000 < 0.05 means h0 is rejected. 5) Differences in 100 meters of skill results between interval training methods with high reaction time and continuous training method with high reaction time (A1B1 - A2B1) valued at 0.000 < 0.05 means h0 is rejected. 6) Differences in 100 meters of skill result between interval training method with high reaction time and mixed reaction method with high reaction time (A1B1 - A3B1). Value = 0,000 < 0,05 means h0 is rejected. 7) Differences in 100 meter running skills results between continuous training method with high reaction time and high mixed reaction method (A2B1 - A3B1) method = 0,000 < 0,05 means h0 is rejected. 8) Differences in the results of 100 meter running skills between interval training methods with low reaction time and continuous training method with low reaction time (A1B2 - A2B2) valued = 0.413 > 0.05 means h0 received. 9) Differences in the results of 100 meter running skills between interval training methods with low reaction time and mixed reaction method with low reaction time (A1B2 - A3B2) worth = 0.0155 < 0.05 means h0 is rejected. 10) The difference of 100 meter running skill result between continuous training method with low reaction time and mixed reaction method with low reaction time(A2B2 - A3B2) worth = 0,026 < 0,05 means h0 is rejected.

Keywords: Skills Sprint 100 Meters, Exercise Method And Reaction Time
THE EFFECT OF POWER LIMBS, SPEED REACTION, FLEXIBILITY AND SELF CONFIDENCE ON THE ACHIEVEMENT OF ELITE ATHLETES ATHLETIC WEST JAVA IN THE TRACK NUMBER
Authors: Lengkana Anggi Setia , Tangkudung James , Asmawi Moch. 
Published: January 2019

This study aims to reveal the effect of limb power, reaction speed, flexibility and confidence in the performance of athletic elite athletes on track numbers. This research was conducted at Universitas Pendidikan Indonesia (UPI) Lab. Sport Faculty of Sport and Health Education (FPOK), with a sample of 31 athletes. The analytical technique used in this study is to use path analysis (Path Analysis), with the aim to identify the influence between variables. The results showed that: (1). Power Limbs affect the achievement of elite athletes by 51.7%. (2). The speed of the reaction had an effect on the achievement of elite athletes by 49.3%. (3). Flexibility has no effect on elite athletes achievement of 0.3%. (4). Confidence affects the achievement of elite athletes by 20%. (5). Limb power affects 40.5% confidence. (6). The speed of the reaction affects the confidence of 30.7%. (7). Flexibility has no effect on confidence of 23.2%.

Keywords: Performance of elite athlete, athletic, limb power, reaction speed, flexibility and self confidence
THE EFFECT OF EYE-FOOT COORDINATION, FLEXIBILITY OF THE LIMBS, BODY BALANCE AND SELF-CONFIDENCE TO THE ACCURACY OF THE FOOTBALL OF SEPAK TAKRAW
Authors: Jufrianis Jufrianis , Akbar Akbar , Tangkudung James 
Published: January 2019

The purpose of this study was to obtain the effect of eye-foot coordination, flexibility of the limbs, body balance and self-confidence to the accuracy of the football of sepak takraw. The research method used in this research is the type of quantitative research with causality study approach. Technical Analysis uses a path analysis approach. Total population The study population is 40 athletes, sampling technique with total sampling. The number of samples in this study are 40 athletes who follow the Center for Student Development and Training. the results of this study conclude: (1) foot-eye coordination can directly affect the accuracy of the football on sepak takraw of 6.94% (2) limb formation can directly affect the accuracy of the football's early takraw of 5.96%, 3 ) the balance of the body can directly affect the initial accuracy of sepak takraw by 3.53%, (4) Self-confidence can directly affect the accuracy of the footballing of sepak takraw by 4.38%, (5) foot-eye coordination can affect direct self-confidence of 3.56%, (6) limb formation can directly influence self-confidence of 2.54%, (7) the balance of the body can directly affect self-confidence by 2.36%.

Keywords: Foot-Coordination, Limb Formation, Body Balance, Self Confidence and Accuracy of Football Upper Sepak takraw.
ANALISIS STRATEGI KEUANGAN MATRIKS UNTUK MENGETAHUI TINGKAT PERTUMBUHAN VALUE CREATION PERUSAHAAN BERKELANJUTAN
Authors: Ridwan Kiagus , Purwohedi Unggul , Warokka Ari 
Published: January 2019

ABSTRAK
Perkembangan industri panas bumi di kawasan ASEAN belum optimal, sehingga perusahaan perlu menganalisis kemampuan keuangannya untuk mengetahui permasalahan yang terjadi di dalam perusahaan. Konsep penciptaan nilai dan manajemen pertumbuhan dapat digabungkan untuk menjadi sebuah strategi keuangan matriks. Strategi ini merupakan alat diagnostik yang dapat digunakan untuk mengevaluasi dan menavigasi melalui perubahan kondisi keuangan dan menggambarkan situasi penciptaan nilai seta manajemen pertumbuhan pada periode tertentu, berdasarkan peringkat dan menempatkannya pada matriks kuadran. Penelitian ini menganalisis variabel Growth in sales, SGR, ROIC, WACC, dan spread EVA. Dalam strategi ini, setelah diketahui kondisi keuangan, maka perusahaan dipetakan ke dalam 4 grafik kuadran. Hasilnya bahwa pada tahun penelitian, hampir semua perusahaan yang bergerak di bidang energi panas bumi di kawasan ASEAN berada dalam kondisi defisit kas. Hal ini menyiratkan bahwa perusahaan perlu meningkatkan dana dari sumber internal maupun eksternal dan mempertahankan kemampuan laba. Di masa mendatang, kondisi keuangan perusahaan diharapkan masuk ke kuadran I dan II.
The Validity of Central Venous to Arterial Carbon Dioxide Difference to Predict Adequate Fluid Management during Living Donor Liver Transplantation: A Prospective Observational Study.
Authors: Hosny Hisham , Elayashy Mohamed , Hussein Amr , Mahmoud Ahmed Abdelaal Ahmed , Mukhtar Ahmed , Fetouh Fawzia Aboul , Abdelaal Amr , Said Hany , Abdo Mostafa 
Published: January 2019

Abstract
Background: Patients with End-stage liver disease undergoing orthotopic liver transplantation are prone to serious hemodynamic and metabolic derangements. The study aimed to assess the validity of central and pulmonary veno-arterial CO2 gradients to predict fluid responsiveness and to guide fluid management during liver transplantation.
Methods: In adult recipients of liver transplantation, ASA III to IV, pulse pressure variations (PPV) guided intraoperative fluid management. PPV of ≥15% (Fluid Responding Status-FRS) indicated fluid resuscitation with 250 ml albumin 5% boluses repeated if required to correct PPV to <15% (Fluid non-Responding Status-FnRS). Samples from central venous and pulmonary artery catheters (PAC) were collected simultaneously to calculate both the central venous to arterial CO2 gap [C(v-a) CO2 gap] and the pulmonary venous to arterial CO2 gap [Pulm(p-a) CO2 gap].
Results: Primary outcome was the sensitivity of central venous CO2 gap to differentiate between fluid responding and non-responding states with 67 data points recorded (20 FRS and 47 FnRS). The discriminative ability of central and pulmonary CO2 gaps between the two statuses (FRS and FnRS) was poor with AUC of ROC of 0.698 and 0.570 respectively. The central CO2 gap was significantly higher in FRS than FnRS (P=0.016), with no difference in pulmonary CO2 gap between both statuses. The central and pulmonary CO2 gaps were weakly correlated to PPV [r=0.291, (P=0.017) and r=0.367, (P=0.002) respectively]. No correlation between both CO2 gaps and both CO and lactate could be seen.
Conclusion: The Central and the Pulmonary CO2 gaps cannot be used as valid tools to predict fluid responsiveness and to guide fluid management during liver transplantation. CO2 gaps also do not correlate well with the changes in PPV or CO.
Comparison of Postoperative Pain between Patients who underwent Primary and Repeated Caesarean Section: A Prospective Cohort Study
Authors: Duan Guangyou , Yang Guiying , Peng Jing , Duan Zhenxin , Li Jie , Tang Xianglong , Li Hong 
Published: January 2019

Abstract
Background: The presences of differences in post-operative pain are unclear between the primipara who underwent a primary cesarean section and multipara who underwent first repeat cesarean section. The study aimed to explore the possible difference in postoperative pain between primipara and multipara.
Methods: Women who underwent cesarean deliveries under spinal anesthesia were included, and postoperative patient-controlled intravenous analgesia was performed. Postoperative incision and visceral pain within 48 hours after the surgery were evaluated. Serum leukocyte and neutrophil counts before and 24 hours after the surgery were retrospective collected. Additionally, the patients’ pain statuses on postoperative week 1 and week 4 were also assessed during follow-up via telephone.
Results: A total of 168 patients (67 primipara and 101 multipara) were included. The multipara showed less risk for experiencing moderate to severe incision pain during the 48 hours after the surgery than the primipara (15.8%vs.37.3%; P=0.001). In patients under 30 years old, inadequate treatment of the visceral pain in the multipara was higher than that of the primipara (22.7%vs.6.4%; P=0.026). There was no significant difference in the combined incidence of inadequate analgesia in both types of pain between the multipara and primipara (33.7%vs.40.2%, P=0.381). Additionally, a significantly higher incidence of pain at 4 weeks after the surgery was noted in the primipara compared to the multipara (55.4%vs.36.1%, P=0.015).
Conclusions: Individual differences between the primipara and multipara should be considered in the management of postoperative analgesia for those who have undergone Cesarean deliveries.
Programmed Intermittent Boluses of Ropivacaine may Provide Superior Analgesia Compared with Continuous Infusion via Paravertebral Catheters following Thoracic Surgery
Authors: Bishop Bridget , Willshire Luke , Kilpin Matthew , Tan Chong , Weinberg Laurence , Pearce Brett 
Published: January 2019

Abstract
Background: Extrapleural paravertebral local anaesthetic catheters are an effective method of post-operative analgesia. We investigated if delivery of ropivacaine via programmed intermittent boluses provided superior analgesia to continuous infusion alone in patients after thoracic surgery.
Methods: A single-centre, retrospective study of 84 adult patients who received an extrapleural paravertebral catheter following thoracic surgery was performed. Patients were stratified into two groups based on the percentage of the total daily ropivacaine dose delivered as a bolus: continuous infusion (< 10%; n = 29) and programmed intermittent bolus (> 10%; n = 55). Outcomes included opioid consumption, pain scores, and ketamine use.
Results: Both groups were comparable. Mean (standard deviation) oral morphine equivalent daily dose consumption on day one, the primary outcome, was 173.4mg (139.7mg) for the continuous infusion group compared to 129.2mg (100.4mg) for the programmed intermittent bolus group, p = 0.10. On day two, the mean (standard deviation) was 149.8mg (130.2mg) and 102.5mg (94.6mg) respectively, p = 0.08. On day three this reached significance with 178.1mg (150.6mg) for the continuous infusion group compared to 80.1mg (74.6mg) for the programmed intermittent bolus group, p = 0.001. There was also a reduction in the number of patients requiring ketamine in the programmed intermittent bolus group on day two (p = 0.02) and day three (p = 0.04). There was no difference in pain scores.
Conclusion: In patients receiving extrapleural paravertebral catheters after thoracic surgery, the delivery of ropivacaine via programmed intermittent boluses may provide superior analgesia compared to continuous infusion alone.
Abnormal Sleep Behaviours Across the Spectrum of Alzheimer’s Disease Severity: Influence of APOE Genotypes and Lewy Bodies
Authors: Koo Ka Yi G. , Schweizer Tom A. , Fischer Corinne E. , Munoz David G. 
Published: January 2019

Background:
The Apolipoprotein (APOE) ε4 allele is a well-known risk factor for Alzheimer’s
Disease (AD), and sleep disturbances are commonly associated with AD. However, few studies
have investigated the relationship between APOE ε4 and abnormal sleep patterns (N+) in AD.

Objective:
To examine the relationship between APOE genotype, Lewy body pathology, and abnormal
sleep patterns in a large group of subjects with known AD load evaluated upon autopsy.

Method:
Data from 2,368 cases obtained from the National Alzheimer’s Coordinating Centre database
were categorized as follows: Braak Stage V/VI and CERAD frequent neuritic plaques as high load AD,
Braak Stage III/IV and moderate CERAD as intermediate load AD, and Braak Stage 0/I/II and infrequent
CERAD as no to low load AD. Cases discrepant between the two measures were discarded.

Results:
Disrupted sleep was more frequent in males (42.4%) compared to females (35.1%), and in carriers
(42.3%) as opposed to non-carriers (36.5%) of ε4. Amongst female subjects with high AD load and
Lewy body pathology, homozygous (ε4/ε4) carriers experienced disrupted sleep more often compared
with heterozygous (ε4/x) or non-carriers of ε4. Such recessive, gender-specific, and Lewy body association
is reminiscent of the ε4 effect on psychosis in AD. However, such association was lost after adjusting
for covariates. In subjects with no to low AD pathology, female ε4 carriers had significantly more
nighttime disturbances than non-carriers; this effect is independent of the presence of Lewy body pathology.

Conclusion:
The influence of APOE ε4 on sleep disturbances is dependent on gender and severity of
AD load.
Gefitinib Represses JAK-STAT Signaling Activated by CRTC1-MAML2 Fusion in Mucoepidermoid Carcinoma Cells
Authors: Wu Yufeng , He Zhen , Li Shaomei , Tang Hong , Wang Lili , Yang Sen , Dong Bing , Qin Jianjun , Sun Yue , Yu Han , Zhang Yu , Zhang Yi , Guo Yongjun , Wang Qiming 
Published: January 2019

Background:Gefitinib is well-known as a tyrosine kinase inhibitor targeting non-smalllung- cancer (NSCLC) containing EGFR mutations. However, its effectiveness in treating mucoepidermoid carcinoma (MEC) without such EGFR mutations suggests additional targets.Objective:The CRTC1-MAML2 (C1-M2) fusion typical for MEC has been proposed to be a gefitinib target.Methods:To test this hypothesis, we developed a set of siRNAs to down-regulate C1-M2 expression. RNA-seq and Western blot techniques were applied to analyze the effects of gefitinib and siC1-M2 on the transcriptome of and the phosphorylation of tyrosine kinases in a MEC cell line H292.Results:Deep-sequencing transcriptome analysis revealed that gefitinib extensively inhibited transcription of genes in JAK-STAT and MAPK/ERK pathways. Both siC1-M2 and gefitinib inhibited the phosphorylation of multiple signaling kinases in these signaling pathways, indicating that gefitinib inhibited JAK-STAT and MAPK/ERK pathways activated by C1-M2 fusion. Moreover, gefitinib inhibition of EGFR and MAPK/ERK was more effective than that of AKT, JAK2 and STATs, and their dependence on C1-M2 could be uncoupled. Taken together, our results suggest that gefitinib simultaneously represses phosphorylation of multiple key signaling proteins which are activated in MEC, in part by C1-M2 fusion. Gefitinib-repressed kinase phosphorylation explains the transcriptional repression of genes in JAK-STAT and MAPK/ERK pathways.Conclusion:These findings provide new insights into the efficacy of gefitinib in treating mucoepidermoid carcinoma, and suggest that a combination of gefitinib and other inhibitors specifically against C1-M2 fusion could be more effective.