bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing the Skill of Medium-Range Ensemble Precipitation and Streamflow Forecasts from the Hydrologic Ensemble Forecast Service (HEFS) for the Upper Trinity River Basin in North Texas
Authors: Kim Sunghee , Sadeghi Hossein , Limon Reza Ahmad , Saharia Manabendra , Seo Dong-Jun , Philpott Andrew , Bell Frank , Brown James , He Minxue 
Published: August 2018

Abstract
To issue early warnings for the public to act, for emergency managers to take preventive actions, and for water managers to operate their systems cost-effectively, it is necessary to maximize the time horizon over which streamflow forecasts are skillful. In this work, we assess the value of medium-range ensemble precipitation forecasts generated with the Hydrologic Ensemble Forecast Service (HEFS) of the U.S. National Weather Service (NWS) in increasing the lead time and skill of streamflow forecasts for five headwater basins in the upper Trinity River basin in north-central Texas. The HEFS uses ensemble mean precipitation forecasts from the Global Ensemble Forecast System (GEFS) of the National Centers for Environment Prediction (NCEP). For comparative evaluation, we verify ensemble streamflow forecasts generated with the HEFS forced by the GEFS forecast with those forced by the short-range quantitative precipitation forecasts (QPFs) from the NWS West Gulf River Forecast Center (WGRFC) based on guidance from the NCEP’s Weather Prediction Center. We also assess the benefits of postprocessing the raw ensemble streamflow forecasts and evaluate the impact of selected parameters within the HEFS on forecast quality. The results show that the use of medium-range precipitation forecasts from the GEFS with the HEFS extends the time horizon for skillful forecasting of mean daily streamflow by 1–3 days for significant events when compared with using only the 72-h River Forecast Center (RFC) QPF with the HEFS. The HEFS forced by the GEFS also improves the skill of two-week-ahead biweekly streamflow forecast by about 20% over climatological forecast for the largest 1% of the observed biweekly flow.
Instability-Driven Benthic Storms below the Separated Gulf Stream and the North Atlantic Current in a High-Resolution Ocean Model
Authors: Schubert René , Biastoch Arne , Cronin Meghan F. , Greatbatch Richard J. 
Published: August 2018

AbstractBenthic storms are important for both the energy budget of the ocean and for sediment resuspension and transport. Using 30 years of output from a high-resolution model of the North Atlantic, it is found that most of the benthic storms in the model occur near the western boundary in association with the Gulf Stream and the North Atlantic Current, in regions that are generally collocated with the peak near-bottom eddy kinetic energy. A common feature is meander troughs in the near-surface jets that are accompanied by deep low pressure anomalies spinning up deep cyclones with near-bottom velocities of up to more than 0.5 m s−1. A case study of one of these events shows the importance of both baroclinic and barotropic instability of the jet, with energy being extracted from the jet in the upstream part of the meander trough and partly returned to the jet in the downstream part of the meander trough. This motivates examining the 30-yr time mean of the energy transfer from the (annual mean) background flow into the eddy kinetic energy. This quantity is shown to be collocated well with the region in which benthic storms and large increases in deep cyclonic relative vorticity occur most frequently, suggesting an important role for mixed barotropic–baroclinic instability-driven cyclogenesis in generating benthic storms throughout the model simulation. Regions of the largest energy transfer and most frequent benthic storms are found to be the Gulf Stream west of the New England Seamounts and the North Atlantic Current near Flemish Cap.
Determining Ergonomic Smartphone Forms With High Grip Comfort and Attractive Design
Authors: Lee Songil , Kyung Gyouhyung , Yi Jihhyeon , Choi Donghee , Park Sungryul , Choi Byeonghwa , Lee Seungbae 
Published: August 2018

Objective: The authors aimed to identify ergonomic smartphone forms by investigating the effects of hand length, four major smartphone dimensions (height, width, thickness, and edge roundness), and smartphone mass on grip comfort and design attractiveness. Background: Despite their potential effect on grip comfort and design attractiveness, the dimensions specified above have never been simultaneously considered in a study investigating smartphone gripping. Method: Seventy-two young individuals participated in a three-stage study. Stage 1 determined the ranges of the four smartphone dimensions suitable for grip comfort and identified the strengths of their influences. Stage 2 investigated the effects of width and thickness (determined to have the greatest influence) on grip comfort and design attractiveness. Mock-ups of varying masses were fabricated using the dimensions determined during the first two stages to investigate the effect of mass on grip comfort and design attractiveness in Stage 3. Results: Phone width was found to significantly influence grip comfort and design attractiveness, and the dimensions of 140 × 65 (or 70) × 8 × 2.5 mm (height × width × thickness × edge roundness) provided high grip comfort and design attractiveness. The selected dimensions were fit with a mass of 122 g, with masses in the range of 106–137 g being comparable. Conclusion: The findings of this study contribute to ergonomic smartphone design developments by specifying dimensions and mass that provide high grip comfort and design attractiveness. Application: The dimensions and mass determined in this study should be considered for improving smartphone design grip comfort and attractiveness.
Association between socioeconomic attainments and suicidal ideation by age groups in Korea
Authors: Kim Joongbaeck , Yoon Soo-Yeon 
Published: August 2018

Background: Suicidal ideation is a strong antecedent of suicidal behavior, associated with increased likelihood of suicide. Thus, suicidal ideation serves to identify which groups are at more risk of suicide and has policy implications for targeting groups to prevent suicide. Aims: A substantial body of research has addressed potential determinants of suicide ideation in Korea. Little attention has been paid, however, to analyzing the extent to which socioeconomic attainments (education, household income, and employment status) are associated with risk of suicidal ideation, drawing on nationally representative data. Methods: Data were drawn from the 2012 Korea Welfare Panel Study (KOWEPS). Among the 12,606 respondents, the findings are based on 1,500 young adults (age 18–35) and 3,469 middle-aged adults (age 36–55) who answered a question about suicidal ideation. Results: For young adults, respondents from 2-year and 4-year colleges and higher had lower probabilities of suicidal ideation compared with respondents from high school. People out of the labor force also exhibited an elevated risk of suicidal ideation compared with those in waged employment. Middle-aged adults displayed different patterns. Middle-aged respondents from 4-year colleges or higher had an increased likelihood of suicidal ideation. The likelihood of reporting suicidal ideation was predicted to decrease as household income increased only for middle-aged adults. Conclusions: The information about suicidal ideation was obtained from only one question of self-response, which limits the validity of the suicidal ideation measurement. The cross-sectional setting of the data prevents us from estimating causal relationships. Nevertheless, the findings imply that age-specific policy should be implemented to ameliorate differential risk for suicidal ideation and benefit public mental health in the long run.
Scapular Tip Free Flap in Composite Head and Neck Reconstruction
Authors: Tracy Jeremiah C. , Brandon Bryan , Patel Samip N. 
Published: August 2018

ObjectivesTo describe the use of the scapular tip free flap (STFF) in the reconstruction of head and neck defects.Study DesignCase series with chart review.SettingAcademic medical center.Subjects and MethodsA review of the electronic medical record was performed of all patients who underwent head and neck reconstructive surgery with STFFs from January 1, 2014, through January 1, 2016. Details regarding the disease, defect reconstructed, and surgical outcomes were quantified.ResultsThirty‐one consecutive cases were performed at our institution within the period reviewed. The procedures included reconstruction of 5 maxillectomy and 26 mandibulectomy defects. The mean length of mandible reconstructed was 6.8 cm (95% CI, 6.01‐7.59; range, 4.0‐10.2). Osteotomies were made to contour the scapular bone in 11 cases, including double osteotomies performed in 2 cases. The most common surgical complications were orocutaneous fistula and postoperative hematoma, which occurred in 3 (10%) and 2 (6.5%) of 31 patients, respectively.ConclusionThis series describes a large number of STFFs performed in head and neck reconstruction. The average length of bony defect repair can be significantly larger than what was previously described. Performing osteotomies to the STFF allows for application to anterior mandibular defects. The STFF offers a large soft tissue component, a relatively long pedicle, and acceptable donor site morbidity. The STFF is a versatile reconstructive option that should be considered to address composite defects of the head and neck.
Balloon Catheter Dilation of the Sinuses: A 2011‐2014 MarketScan Analysis
Authors: Jang David W. , Abraham Cecily , Cyr Derek D. , Schulz Kristine , Abi Hachem Ralph , Witsell David L. 
Published: August 2018

ObjectiveThis study uses a large national claims‐based database to analyze recent practice patterns related to balloon catheter dilation (BCD) of the sinuses.Study DesignRetrospective study.SettingAcademic.Subjects and MethodsPatients with chronic rhinosinusitis (CRS) undergoing BCD and functional endoscopic sinus surgery (FESS) from 2011 to 2014 were identified in Truven Health MarketScan Databases with codes from the International Classification of Diseases, Ninth Revision, Clinical Modification and Current Procedural Terminology, Fourth Edition. Prevalence of CRS and frequency of sinus procedures were trended over the study period. Information related to site of service, demographics, and comorbidities was analyzed.ResultsAlthough the prevalence of CRS and sinus procedures remained stable over the study period, there was a consistent increase in the annual number of BCD procedures performed in the office. Among BCD procedures, multisinus dilation had the largest increase. A higher proportion of patients undergoing BCD were women, aged ≥65 years, and from the South. There was a higher prevalence of headache disorder and allergic rhinitis in the BCD group, as compared with the FESS and hybrid groups.ConclusionBCD, especially in the office, has risen in popularity since the introduction of Current Procedural Terminology codes in 2011. This study reveals significant differences in demographics and comorbidities between patients undergoing BCD and those undergoing FESS. Such disparities may highlight the need for better‐defined indications for use of this technology.
Elements for developing community-based interventions for adults with fetal alcohol spectrum disorder: A scoping review
Authors: Quan Ryan , Brintnell E Sharon , Leung Ada WS 
Published: August 2018

Introduction Current literature about interventions for adults with fetal alcohol spectrum disorder (FASD) is limited, which is a concern, due to the high prevalence of FASD. FASD creates lifelong physical, mental, cognitive and behavioral deficits, which impacts many aspects of daily living. Community-based interventions are necessary to better support adults with FASD and provide them with the opportunity to achieve success in their daily lives and social participation. This scoping review aimed to identify elements for developing successful community-based interventions for these individuals. Method A search was conducted in the MEDLINE, PsycINFO, CINAHL, and EMBASE databases and supplementary gray literature was resourced. Articles were selected based on inclusion–exclusion criteria, and a thematic analysis was completed to identify and present relevant findings. Results Seven articles met selection criteria and were included in this review. Six emerging themes were identified: inclusion of a functional context, individualized support, education for service providers, structure and routine, utilizing a strengths-based approach, and environmental adaptations. These themes were used to present the findings related to the elements necessary for developing interventions for adults with FASD. Conclusion The results indicate that the identified elements may be necessary to develop successful interventions, especially community-based interventions, for adults with FASD.
Clinical Outcomes, Tendon Integrity, and Shoulder Strength After Revision Rotator Cuff Reconstruction: A Minimum 2 Years’ Follow-up
Authors: Willinger Lukas , Lacheta Lucca , Beitzel Knut , Buchmann Stefan , Woertler Klaus , Imhoff Andreas B. , Scheiderer Bastian 
Published: August 2018

Background: The retear rate after primary rotator cuff (RC) reconstruction is high and commonly leads to poorer clinical outcomes and shoulder function. In the case of primary failure, revision RC reconstruction (RCR) has become increasingly important to re-create RC integrity and improve outcomes. To date, clinical and structural outcomes after RCR have not been sufficiently investigated and described at midterm follow-up. Hypothesis/Purpose: The purpose was to evaluate the clinical and radiological outcomes after revision RCR. It was hypothesized that revision RCR significantly improves clinical outcomes and that the outcomes positively correlate with tendon integrity on magnetic resonance imaging (MRI). Study Design: Case series; Level of evidence, 4. Methods: Patients who underwent revision RCR between 2008 and 2014 were retrospectively evaluated with a minimum follow-up of 2 years. Outcomes were assessed by a clinical examination, a visual analog scale for pain (VAS), the Constant Score (CS), the American Shoulder and Elbow Surgeons (ASES) score, and the Disabilities of the Arm, Shoulder and Hand (DASH) score. Tendon integrity was determined using 3-T MRI and graded according to the Sugaya classification. Results: Thirty-one of 40 patients (77.5%) were available for the final assessment at a mean follow-up of 50.3 ± 20.4 months. Clinical outcome scores significantly improved from preoperatively to postoperatively for the CS (39.7 ± 16.7 to 65.1 ± 19.7; P < .001), ASES (44.2 ± 17.7 to 75.2 ± 24.8; P < .001), and DASH (68.6 ± 15.1 to 21.5 ± 19.1; P < .001). The VAS score decreased from 6.1 ± 1.8 preoperatively to 1.3 ± 1.8 at final follow-up ( P < .001). MRI demonstrated a retear rate of 55.5%. No differences in CS, ASES, and DASH scores were detected between patients with an intact repair and failure. Abduction strength was not significantly different in patients with an intact repair and retears (55.5 N vs 44.0 N, respectively, P = .52). Conclusion: Revision RCR improves clinical outcomes and shoulder function at midterm follow-up. The clinical outcome scores were comparable in patients with an intact repair and those with failed RC healing. Therefore, tendon integrity was not correlated with better clinical outcomes after revision RCR at final follow-up.
Resistenze antibiotiche e nuove molecole: qual è lo scenario attuale?
Authors: Novelli Andrea 
Published: August 2018

Antibiotic resistance and new drugs in urologic setting: what we need to know? Urinary tract infections (UTIs) are among the most frequent infectious diseases, and represent an important public health problem with a substantial economic burden. In recent years the chemoresistance of the main uropathogens has significantly increased worldwide. Extended spectrum beta-lactamase (ESBL) production and multi-drug resistant (MDR) clones of Escherichia coli and Klebsiella pneumoniae are limiting available treatment options. Carbapenems and aminoglycosides are still effective in complicated UTI. New beta-lactam combinations such as ceftolozane-tazobactam and ceftazidime-avibactam may be highly useful in treating severe infections while contributing to the carbapenem sparing strategy. For uncomplicated UTI, within older antibiotics, fosfomycin trometamol may be considered a first-choice drug since it is still retaining a good activity against MDR uropathogens. On the other hand, there are extensive data showing that the administration of antimicrobials according to pharmacokinetic/pharmacodynamic (PK/PD) parameters improves the possibility of a positive clinical outcome, particularly in severely ill patients. Evidence is growing that when PK/PD parameters are used to target not only clinical cure. This article discusses the PK/PD characteristics of antimicrobial agents for the treatment of UTIs, and the pharmacological and therapeutic strategies for limiting or preventing bacterial resistance.
A healthy dietary pattern associates with a lower risk of a first clinical diagnosis of central nervous system demyelination
Authors: Black Lucinda J , Rowley Charlotte , Sherriff Jill , Pereira Gavin , Ponsonby Anne-Louise , Lucas Robyn M 
Published: August 2018

Background: The evidence associating diet and risk of multiple sclerosis is inconclusive. Objective: We investigated associations between dietary patterns and risk of a first clinical diagnosis of central nervous system demyelination, a common precursor to multiple sclerosis. Methods: We used data from the 2003–2006 Ausimmune Study, a case–control study examining environmental risk factors for a first clinical diagnosis of central nervous system demyelination, with participants matched on age, sex and study region. Using data from a food frequency questionnaire, dietary patterns were identified using principal component analysis. Conditional logistic regression models ( n = 698, 252 cases, 446 controls) were adjusted for history of infectious mononucleosis, serum 25-hydroxyvitamin D concentrations, smoking, race, education, body mass index and dietary misreporting. Results: We identified two major dietary patterns – healthy (high in poultry, fish, eggs, vegetables, legumes) and Western (high in meat, full-fat dairy; low in wholegrains, nuts, fresh fruit, low-fat dairy), explaining 9.3% and 7.5% of variability in diet, respectively. A one-standard deviation increase in the healthy pattern score was associated with a 25% reduced risk of a first clinical diagnosis of central nervous system demyelination (adjusted odds ratio 0.75; 95% confidence interval 0.60, 0.94; p = 0.011). There was no statistically significant association between the Western dietary pattern and risk of a first clinical diagnosis of central nervous system demyelination. Conclusion: Following healthy eating guidelines may be beneficial for those at high risk of multiple sclerosis.
Flow diverter for endovascular treatment of intracranial mirror segment internal carotid artery aneurysms
Authors: Kühn Anna Luisa , Kan Peter , Srinivasan Visish , Rex David E , de Macedo Rodrigues Katyucia , Howk Mary C , Wakhloo Ajay K , Puri Ajit S 
Published: August 2018

Background To evaluate the feasibility and efficacy of the pipeline embolization device in the treatment of unruptured intracranial mirror segment aneurysms. Methods Out of a total of 338 subjects, 14 were identified harboring a total of 32 internal carotid artery mirror segment aneurysms that were treated with the pipeline embolization device and were consecutively enrolled into our study. We collected data on patient demographics, modified Rankin scale (mRS) at admission, aneurysm characteristics, clinical outcome at discharge, 3–9 and at 12–18 months as well as angiography results at follow-up. Results Patients’ mean age was 52.9 years; baseline mRS was 0 in all subjects. Pipeline embolization device placement was successful in all cases. Post-treatment mRS remained 0 in 13/14 patients. One patient experienced a small intraparenchymal hemorrhage and subarachnoid hemorrhage, associated with a frontoparietal infarction resulting in right upper extremity weakness and aphasia (post-treatment mRS 3). His mRS evaluation remained stable at the 3–9-month follow-up. Three to 9-month follow-up angiography (13/14 subjects) showed complete aneurysm occlusion in 24/30 aneurysms (80%), near complete and partial occlusion in three of 30 (10%) aneurysms each. At the 9-month follow-up, one patient experienced a complete occlusion of the anterior temporal artery branch but did not present with any clinical deficits. No mRS changes were encountered over a median 6-month follow-up period. Mid-term follow-up angiography (12–18 months) available in eight of 14 subjects showed complete aneurysm occlusion in all patients. Mild intimal hyperplasia was observed in one patient. Conclusions Flow diversion technology can be used for the treatment of unruptured mirror segment aneurysms in selected patients.
Direct oral anticoagulants for stroke prevention in atrial fibrillation: treatment outcomes and dosing in special populations
Authors: Stacy Zachary A. , Richter Sara K. 
Published: August 2018

Background: To review data from the pivotal phase III trials evaluating the efficacy and safety of direct oral anticoagulants (DOACs) versus warfarin for stroke prevention in patients with nonvalvular atrial fibrillation (NVAF), and to summarize the major findings with regards to patient subgroups that are at an increased risk for stroke or bleeding. Methods: A PubMed literature search (January 2009 to January 2017) was performed using the terms ‘dabigatran’, ‘rivaroxaban’, ‘apixaban’, ‘edoxaban’, ‘atrial fibrillation’, ‘RE-LY’, ‘ROCKET AF’, ‘ARISTOTLE’, and ‘ENGAGE AF-TIMI 48’. All primary publications and secondary analyses in special populations at increased risk of stroke or bleeding from the pivotal phase III clinical trials were evaluated. Results: Available secondary analyses indicate no treatment interactions with regards to stroke or systemic embolic event (SEE) prevention for any of the DOACs in the patient subgroups, including patients with advanced age, impaired renal function, diabetes, prior stroke, concomitant antiplatelet therapy, heart failure, prior stroke, history of hypertension, myocardial infarction (MI), coronary artery disease, and peripheral artery disease (PAD). Although higher bleeding incidence was reported with dabigatran and rivaroxaban in patients aged 75 years and over with apixaban in patients with diabetes, and with rivaroxaban in patients with previous MI or PAD, no changes in dosing are recommended. Conclusions: Overall, results of secondary analyses indicate that the recommended dosing strategy for each of the DOACs produces a consistent anticoagulant effect across a diverse patient population, including those at increased risk of stroke or bleeding.