bluuebunny/crossref_metadata_2025_split huggingface dataset:
ENTERTAINMENT INFRASTRUCTURE IN THE BLACK SEA PROVINCE AS A REFLECTION OF SOCIO-CULTURAL REQUESTS OF THE REGIONAL COMMUNITY (late 19th - early 20th century)
Authors: KTITOROV Sergey N. , KTITOROVA Оlga V. 
Published: March 2019

The article discusses the formation of entertainment infrastructure in the cities of the Black Sea province in the late 19th - early 20th century. in close connection with the development of the recreational function of the region. The dependence of the process of creation and activity of leisure establishments on the sociocultural demands and needs of the regional community is shown. The characteristic of natural geographic, socio-economic, demographic and other factors influencing the organization of various forms of recreation, both visitors and local residents, is given. The authors conclude that entertainment for members of regional society was one of the ways to overcome the feeling of alienation and isolation from the outside world. The focus of the article is on the consideration of cinemas and circuses, which in the pre-revolutionary period in Russia were the most popular entertainment establishments and attracted the largest number of viewers. The study provides detailed statistical information about cinemas in Novorossiysk and other cities of the Black Sea province, assesses their material base, characterizes the genre variety of the repertoire. Also highlights the specifics of organizing circus performances, and other leisure activities. It justifies the conclusion that the extensive network of entertainment establishments that developed in the Black Sea cities in the pre-revolutionary period served the sociocultural requests of both the local population and the visiting resort community, and their activity became one of the factors shaping a specific urban lifestyle that is brighter and more dynamic than weekdays Russian village. According to the authors, the spread among various social groups of citizens of various forms of leisure was a reflection of the democratization of society and was the result of modernization processes sweeping the country.
PROSPECTS OF INVOLVEMENT OF MODERN STUDENTS IN RESEARCH ACTIVITIES (ON THE MATERIALS OF THE TULA REGION)
Authors: LABZINA Irina A. 
Published: March 2019

The article deals with the reasons of the low degree of involvement of young people in scientific activities. It is noted that the popularization of this direction helps to improve not only economic, technological and other indicators, but also the whole social life. The involvement of young people, and in particular students, in research activities plays a huge role, as implemented developments often carry an innovative approach and allow to develop several possible variations not only to solve urgent problems, but also for their further integration into other priority areas. This paper describes the reasons why there is a fairly low level of student activity in scientific, research and project activities. Studying the aspects of this problem, the above is confirmed by the sociological research in the form of a questionnaire, which allows to identify the degree of motivation among students. It is fixed that at this stage it is difficult to use the means of motivation in full on the basis of the lack of a resource that can contribute to this and bring information to the audience. It is concluded that the basic source is necessary for the actualization of a particular direction. In the age of information and technological progress communication in society, the development and promotion of various ideas and directions is achieved through the use of the media component [3]. Various ways of solution are considered and as the most optimal it was revealed that the source, which will serve as a tool for the dissemination of information about research activities, is a website on the Internet, and the means of its actualization in the appropriate target audience can be designated pages in social networks. It is also noted that the development of the above resources in the social network is the most effective, as young people devote an impressive amount of time to social networks and they are the main source of information for them. The author believes that the introduction and distribution of content about various competitions, conferences, exhibitions and competitions actualizes scientific activities.
Modeling the effect of enzyme replacement therapy on life-threatening complications in patients with Fabry disease
Authors: Ignatyeva V. I. , Moiseev S. V. , Bulanov N. M. , Karovajkina E. A. , Moiseev A S. 
Published: March 2019

Fabry disease (FD) is a severe lysosome storage disease caused by congenital deficiency of the enzyme α-galactosidase A and characterized by the risk of renal failure combined with cardiovascular and CNS complications. According to the currently available information, the early start of enzyme replacement therapy (ERT) leads to a significant improvement in patient’s condition.The aim of the studyis to assess whether the timely ERT prevents severe FD complications and to calculate the number of prevented cases as depending on the time of ERT start.Materials and methods. The proposed model is based on the published results on patients with FD, receiving agalsidase alpha as ERT (no data for agalsidase beta was found). The expected number of cases with life-threatening complications was calculated for different starting timepoints and durations of the ERT.Results. In patients with FD, continuous ERT during five years reduces the number of serious cardiovascular and renal complications by 25%. An early start of ERT makes it possible to additionally (as compared with a late start) prevent the complications in more than 20% of cases.Conclusion. The early initiation of RPT in patients with FD can significantly reduce the occurrence of severe lifethreatening complications, increase the patients’ survival and improve their quality of life.
Simultaneous Percutaneous Coronary Intervention and Endovascular Closure of Atrial Septal Defect in Adults
Authors: Ioseliani D. G. , Kovalchuk I. A. , Rafaeli T. R. , Rogatova A. N. , Stepanov A. V. , Zakharova O. V. , Pekarskaya M. V. 
Published: March 2019

Aim:to assess clinical efficacy and expediency (appropriateness) of simultaneous single stage combined coronary stenting and closure of atrial septal defect.Materials and methods.Of total number of patients who underwent endovascular correction of atrial septal defect (ASD) (n=91), in 6 (6.6 %) the procedure of endovascular repair of secondary ASD was combined with performed at same session oronary stenting. Mean age of these patients was 63±6.4 years. Mean diameter of ASD according to transesophageal echocardiography was 13.7±3.1 мм (from 10 to 17 mm). Two patients had dysplasia of atrial septum with pronounced aneurysmal protrusion in the right atrial cavity. Estimate of coronary arteries (CA) involvement SYNTAX score was 14.5±4.9.Results.At initial stage we performed coronary stenting, then ASD closure with occluder. Technical success of combined endovascular procedures was 100 %. Six ASD occluders were implanted in 6 patients. Mean occluder diameter was 21±7,3 mm. Immediately after occluder implantation complete defect closure was achieved in 5 cases, in one case small residual shunt was observed. CA stenting procedure, in one patient after successful recanalization of chronic CA occlusion, in all cases was fulfilled without complications. At control examination after 13.5±1.5 months complete closure of defects was preserved. In all cases significant reduction of right heart chambers occurred. According to echocardiography right atrial volume decreased from 48.6±5.6 to 32.6±3.3 cm3, right ventricular volume – from 45.2±5.1 to 33.4±3.8 cm3, systolic pulmonary pressure fell from 49.7±8.6 to 32.6±6.9 mm Hg. According to control coronary angiography good effect of endovascular procedures was preserved. Tolerance to exercise rose from 68.5±11.8 до 85.3±12.4 W.Conclusion.Same time CA stenting and endovascular ASD closure appears to be safe and effective procedure. The strategy used was not associated with additive risk for a patient and shortened duration of hospital stay.
Blood Pressure Levels and Prevalence of Arterial Hypertension in the Population of Residents of the Central Region of Siberia Aged 25–45 Years
Authors: Kovalkova N. A. , Ragino Yu. I. , Hudyakovа A. D. , Denisova D. V. , Voevoda M. I. 
Published: March 2019

Purpose:to study blood pressure levels and the prevalence of hypertension in persons aged 25–45 years in Novosibirsk.Materials and methods.A cross-sectional population study in one of typical areas of Novosibirsk was performed in 2013–2016. The study included 479 men and 612 women aged 25–45 years. Arterial hypertension was defined as blood pressure (BP) ≥140 / 90 mmHg according to Russian recommendations (2004). For analysis two age groups were distinguished: 25–34 years and 35–45 years.Results.Mean values of systolic and diastolic BP were significantly lower in women than in men in age groups. In men and women, the analyzed indicators were significantly higher in the older than in the younger age group. Mean values of pulse pressure in men were significantly higher than in women in both age groups, there were no differences in the analyzed index between age groups in either men or women. Optimal BP was more often recorded among women than among men in both age groups. The proportion of persons with normal BP among men was grate than among women in both age groups. In the age group 35–45 years compared with the younger group, in men there was a decrease in incidence of category with BP<140 / 90 mmHg, an increase of the proportion of persons with hypertension grades 1 and 2, the appearance of persons with grade 3 hypertension; in women – an increase of the proportion of individuals with normal, high-normal BP, and with grade 1 hypertension, appearance of individuals with grades 2 and 3 hypertension. Frequency of BP categories ≥140 / 90 mmHg in age group 25–34 years among men was 17.6 %, among women 3.1 % (p<0.0001); in age group 35–45 years among men – 34.7 %, among women – 12.5 % (p<0.0001).Conclusions.Prevalence of hypertension in men was 28 %, in women – 9 %. Favorable tendencies of BP indicators in both sexes were revealed over a 30-year period, while gender differences did not change.
Features of the clinic and diagnosis of chronic heart failure in patients with chronic obstructive pulmonary disease
Authors: Karoli N. A. , Borodkin A. V. , Rebrov A. P. 
Published: March 2019

Aim.To elucidate clinical and diagnostic features of chronic heart failure (CHF) in patients with chronic obstructive pulmonary disease (COPD).Materials and methods.The study included 239 patients with COPD and 42 patients with CHF without COPD. The first subgroup consisted of 60 patients with a history of myocardial infarction (MI) and the second subgroup consisted of 79 patients without a history of MI. A general clinical examination, EchoCG, measurements of N-terminal pro B-type natriuretic peptide (NT-proBNP), galectin 3, and high-sensitivity C-reactive protein (hsCRP) were performed for all patients.Results.The risk group for excluding HF as a cause of progressive dyspnea in COPD patients consisted of patients with the bronchitic phenotype who belonged to GOLD groups C and D with frequent exacerbations, increased hsCRP, reduced oxygen saturation, and impaired exercise tolerance. Patients with a history of MI constituted a special group of risk. Measuring specific biomarkers, primarily BNP or NT-proBNP, is recommended to confirm the presence/absence of CHF and to evaluate CHF severity in patients with these risk factors.Conclusion.A combination of COPD and CHF produces a number of clinical and, specifically, diagnostic problems, which have not been completely solved so far.
City Center for the Treatment of Chronic Heart Failure: the organiza-tion of work and the effectiveness of treatment of patients with chronic heart failure
Authors: Vinogradova N. G. 
Published: March 2019

Actuality.In the Russian Federation, there has been an increase in the number of patients with chronic heart failure (CHF) of the III–IV functional class, who are characterized by frequent development of acute decompensation of СHF and frequent repeated hospitalizations. This dictates the need to create a system of effective control over the conduct of drug therapy and physical rehabilitation after discharge from the hospital at the outpatient stage.Objective:to identify the differences between the two strategies for monitoringatients with CHF after decompensation and to determine the effectiveness of treatment, rehabilitation measures and life prognosis depending on the observation in the system of the specialized City Center for Treatment of CHF (Heart failure clinic) and in real outpatient practice.Materials and methods:The study included 648 patients hospitalized with decompensation in the inpatient unit of the Center for Treatment CHF. Group 1 consisted of 412 patients who, after discharge, continued rehabilitation and follow-up in the outpatient department of the Center for Treatment CHF. Group 2–326 patients who, after discharge, preferred observation in another outpatient departments of Nizhny Novgorod.Results:After 1 year of observation, the overall mortality rate in group 2 was 14.83 %, and in group 1–4.13 %, (odds ratio (OR) = 4.0, 95 % confidence interval (CI) 2.2–7.4; p <0.001). Cardiovascular mortality was also higher in group 2: 11.4 % versus 3.3 % (OR = 3.8, 95 % CI 2.0–7.4; p <0.001), as well as mortality from decompensation: 7.6 % versus 2.1 % (OR = 3.8, 95 % CI 1.7–8.7; p <0.001). In group 2, non-fatal cardiovascular complications were more common: 5.1 % versus 1.6 % (OR = 3.2, 95 % CI 1.2–8.3; p = 0.01), as well as fatal and nonfatal stroke, pulmonary thromboembolism, venous thromboembolic complications – 6.3 % versus 1.4 % (OR = 4.4, 95 % CI 1, 7–11.6; p <0.001). An increase in the proportion of rehospitalized patients with CHF during the year in group 2 compared with group 1 was recorded: 50.3 % and 31.8 % of patients, respectively (OR = 2.2, 95 % CI 1.5–3.2; p<0.001). Physical activity of patients who were observed in Center for Treatment CHF the was significantly higher than among patients who were treated in another outpatient departments.Conclusion:Management of patients with CHF after decompensation in Heart failure clinic showed better results in comparison with the standard approach: the risks of general, cardiovascular mortality and nonfatal cardiovascular complications were statistically significantly lower. Patients with CHF who refused to be seen at Heart failure clinic were more often hospitalized again during the year.
Heart valve injury due to radiation therapy
Authors: Poltavskaya M. G. , Emelina E. I. , Avdeev Yu. V. , Gendlin G. E. , Paramonova G. N. 
Published: March 2019

Relevance.Radiation therapy (RT) plays an important role in oncology, improving the immediate and long-term results of treatment of a number of tumors. One of the most significant complications of RT are lesions of the heart valves.Objective.To study the variants of valve damage that occur in patients who received radiation therapy for cancer.Patients and methods.A group of patients who, during the period from 1978 to 2002, underwent chemo-radiation therapy (CRT) for Hodgkin's lymphoma (LH) of 2–4 stages with damage to the intrathoracic lymph nodes: 71 patients, 60 of whom did not go to the cardiologist and were invited to be examined, 11 were hospitalized due to clinically significant cardiovascular pathology (CHF, myocardial infarction, angina pectoris, valvular defect, AV block). The study methods included: standard clinical and laboratory examination, spirometry, 24‑hour ECG monitoring, echocardiography, in some patients single-photon myocardial emission tomoscintigraphy (SPECT), and CT scan of the chest organs. In 60 patients, a stress test on an ECG-controlled treadmill was performed, in 18 patients – a maximum stress test on a treadmill with a gas analysis – ergospirometry.Results and discussion. Valve pathology was detected in 49.3 % of cases, most often (in 46.5 %) mitral regurgitation (MR) occurred, primarily due to MR of the 1 st degree, which had no clinical significance. Pathology of the aortic valve (12.7 % of patients) was represented mainly by mild regurgitation (11.3 %). Aortic stenosis was diagnosed in 4.2 % of patients. In the studied cohort of patients, predominantly non-severe valve lesions were detected. In addition, examples of patients with clinically significant valve valvular lesions are presented.
ON NON-QUADRATIC PENALTY FUNCTION FOR NON-LINEAR PROGRAMMING PROBLEM WITH EQUALITY CONSTRAINTS
Authors: Prajapati Raju , Prakash Dubey Om , Pradhan Ranjit 
Published: March 2019

Purpose: The present paper focuses on the Non-Linear Programming Problem (NLPP) with equality constraints. NLPP with constraints could be solved by penalty or barrier methods.
Methodology: We apply the penalty method to the NLPP with equality constraints only. The non-quadratic penalty method is considered for this purpose. We considered a transcendental i.e. exponential function for imposing the penalty due to the constraint violation. The unconstrained NLPP obtained in this way is then processed for further solution. An improved version of evolutionary and famous meta-heuristic Particle Swarm Optimization (PSO) is used for the same. The method is tested with the help of some test problems and mathematical software SCILAB. The solution is compared with the solution of the quadratic penalty method.
Results: The results are also compared with some existing results in the literature.
EVALUATION OF ADSORTIVE POWER OF CACTUS PEAR FORAGE WITHOUT PEEL FOR USE IN REMOVAL OF COMMON GASOLINE IN WATER BODIES
Authors: RIBEIRO LIMA LENILDE MÉRGIA , BANDEIRA CRUZ DA SILVA JOANNY LAYS , CAVALCANTE LAEDSON ENEAS , ALVES FEITOZA EDGLEIGA DAISE , RIBEIRO LIMA LÍGIA MARIA 
Published: March 2019

Alternative methods, as adsorption, with use of readily available and low cost materials have been used to remove contaminants in water bodies. Objective of this work was to study adsorptive power of cactus pear forage (Opuntia tuna Mill) biomass without bark as adsorbent for removal of gasoline in water bodies. Material underwent a natural drying process and then comminution to powder form. In adsorption kinetics study, were evaluated time between 5 and 60 minutes (with a 5-minute interval) and equilibrium concentrations of contaminants ranging from 5 to 50%, with a 5% variation rate. It was observed that process was rapid, with greater adsorption efficiency over time for 30 minutes. Langmuir model fitted well to experimental data, with a maximum adsorption capacity of 5.94 g.g -1. Results confirm that cactus pear forage without peel appears as a promising biomass in gasoline adsorption process.
USE OF THE THEORY OF GAMES AS AN INNOVATIVE METHOD IN THE SOLAR ENERGY INVESTMENT DECISION PROCESS
Authors: Tomaz Monique Suellen de Lima e Silva , Castrillo Lázara Silveira , Cunha Danielle Casé Dionizio , França Aldenis Everton Alves Guilherme , Fittipaldi Eduardo Henrique Diniz 
Published: March 2019

Brazil is a country with high solar energy potential due to the vast unhabitaded areas close to the Equator with high availability of solar radiation. With a simple setting, low maintenance costs, sustainability appeal and an inexhaustible power supply, the solar plants have been transformed in attractive investments in the electrical power sector. In the Brazilian Northeastern region, it's possible to find the best conditions for the development of new solar plants due to the climate, dry and sunny all year. The present work aims to present the use of game theory as an innovative method in the investment decision process between two companies of solar energy generation in Northeastrn region of Brazil. The methodology used for this analysis was the Cournot method to conclude whether competition or cooperation among the agents involved prevails in the market.
DOMÍNIOS AFETADOS NA QUALIDADE DE VIDA DO PACIENTE RENAL CRÔNICO EM TRATAMENTO HEMODIALÍTICO: REVISÃO SISTEMÁTICA
Authors: Evangelista Renata Alessandra , Pires Natália Cristina , Silva Cildiléia Santos , Bueno Alexandre Assis , Silva Luiz Almeida 
Published: March 2019

Objetivo: Sintetizar o conhecimento produzido acerca das publicações na literatura nacional e internacional sobre os domínios afetados na qualidade de vida dos pacientes renais crônicos em tratamento hemodialítico. Método: Foi realizada uma revisão sistemática nas bases de dados, LILACS, MEDLINE e CINAHL, nos últimos 10 anos. Resultados: Foram analisados 9 artigos, a maioria dos estudos eram descritivos e transversais, apresentaram evidências sobre as relações das dimensões afetadas na qualidade de vida dos indivíduos em tratamento hemodialítico. Os achados revelaram baixos escores de qualidade de vida, principalmente no domínio físico, sendo o aspecto social aquele de melhor escore.A identificação dos itens impactantes da qualidade de vida dessa população permite, aos profissionais de saúde, repensar a assistência atualmente oferecida, minimizando as consequências negativas decorrentes desse processo. Conclusão: Revela-se que o cuidado dispensado aos pacientes deve englobar estratégias para melhorar a saúde e qualidade de vida dos pacientes.
ATIVIDADES DE ARTETERAPIA NA REABILITAÇÃO DE USUÁRIOS DA ATENÇÃO PSICOSSOCIAL
Authors: Willrich Janaína Quinzen , Portela Dariane Lima , Casarin Renata 
Published: March 2019

Este estudo objetivou conhecer as contribuições da arteterapia na reabilitação de usuários de um Centro de Atenção Psicossocial (CAPS). Trata-se de uma pesquisa qualitativa realizada em 2016, por meio da aplicação de entrevista semiestruturada. Os dados foram analisados utilizando-se a técnica da análise temática. A partir da análise dividiu-se os resultados em três categorias: desenvolvimento das oficinas terapêuticas, vínculo e participação e contribuição das oficinas terapêuticas na vida dos usuários. Observa-se que as oficinas terapêuticas promoveram a inclusão dos usuários e criação de vínculo, resultando em melhor qualidade de vida. Também verificou-se que os usuários demonstram afeto ao serviço e aos profissionais, e que as oficinas terapêuticas são benéficas para a saúde dos mesmos, ao passo que contribuem para bons relacionamentos familiares e sociais. Dessa forma a construção desse estudo proporcionou a compreensão de que a arteterapia tem um papel fundamental na vida dos usuários, contribuindo para sua reabilitação social.
AÇÕES E ATIVIDADES DESENVOLVIDAS PELA ENFERMAGEM NO CENTRO DE ATENÇÃO PSICOSSOCIAL: REVISÃO INTEGRATIVA
Authors: Silva John Victor dos Santos , Brandão Thyara Maia , Oliveira Keila Cristina Pereira do Nascimento 
Published: March 2019

Objetivo: descrever o que se tem produzido cientificamente sobre as ações e atividades desenvolvidas pelos profissionais de enfermagem nos Centros De Atenção Psicossocial. Metodologia: Trata-se de uma revisão integrativa da literatura, realizada nas bases de dados SciELO, LILACS e BDENF, nos meses de abril e maio, onde a amostra foi de 11 estudos. Resultados: Algumas das ações e atividades são: acolhimento, visitas domiciliares, oficinas e grupos terapêuticos, consulta familiar, organização do CAPS, reunião de equipe, atividades externas, geração de renda, PTS; além de: consulta de enfermagem, administração de medicamentos, educação em saúde, comunicação terapêutica, verificação de sinais vitais e curativos. Conclusão: As ações e atividades são bastante diversificadas, a depender do público de usuários que frequentam os CAPS, e que, na maioria, são exercidas pela equipe de enfermagem ou de forma coletiva com os demais profissionais de outras categorias. Apresentam-se, também, algumas características positivas e negativas que são fatores que podem até potencializar ou fragilizar o trabalho nos serviços.