bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sequential anaerobic–intermittently aerated treatment of textile and domestic wastewater
Authors: Bidu Jerome Michael 
Published: November 2024

ABSTRACT
A laboratory-scale biological system operated in a batch sequential anaerobic–intermittently aerated reactor was used to treat textile wastewater. The anaerobic system was aimed at colour and chemical oxygen demand (COD) removal while the intermittently aerated reactor was responsible for the removal of aromatic amines, nitrogen, and phosphates. Additionally, intermittent aeration was responsible for further removal of COD and colour from the wastewater. Domestic wastewater was added to the raw textile wastewater as a source of easily biodegradable organics. The anaerobic reactor removed colour up to 66%, at hydraulic retention time (HRT) of 9 days and pH of 8.6. COD removal of up to 62% was realized at HRT of 9 days and pH of 7.8. A subsequent intermittently aerated reactor reduced more colour and COD to 68 and 71% respectively at HRT of 3 days. Moreover, 100% removal of nitrates and ammonia was realized in intermittently aerated reactor HRT of 3 days. The HRT of 9 days, pH of 7.8, and the textile wastewater fraction of 0.8 in the anaerobic treatment stage had the highest removal of pollutants. The study revealed that the sequential anaerobic–intermittently aerated reactor system was able to remove colour, COD, and nutrients from wastewater.
Flocculation of Micractinium reisseri for successful harvesting and potential use
Authors: Sahay Sudha , Jain Brigita , Solanki Dharmisha , Dave Shailesh , Suresh Antony 
Published: November 2024

ABSTRACT

This study includes Micractinium reisseri cultivation in artificial saline medium (ASM). With the aim of harvesting the bulk M. reisseri biomass, an experiment was set up at a bench scale to evaluate the best flocculation technique with the least compromising biomass and lipid loss. The flocculation efficiencies for the M. reisseri biomass have been studied using the auto-, bio-, and chemical-flocculation methods. Different concentrations of chitosan for the biological method and alum for the chemical method were added in M. reisseri culture growing in the liquid ASM. The optimal concentration with the highest biomass and oil collection was determined for each method. In the biological method, the highest (96.44%) and lowest (67.88%) flocculation efficiencies were observed by adding 15 and 2 mg of chitosan, respectively, and in the chemical method, the highest (97.2%) and lowest (35.4%) flocculation efficiencies were observed by adding 150 and 50 mg of alum, respectively. The auto-flocculation method shows the highest efficiency (97.8%) among all the tests. The oil yield from the three highest biomasses was 2.60, 1.51, and 1.08% in the auto-, bio-, and chemical-flocculation methods, respectively. The time taken for auto-, bio-, and chemical-flocculation was 48, 4, and 1 h, respectively.
The development of physical state and exhaustion factors monitoring system with capability of collecting, estimating and analysing data for military personnel
Authors: Larina E. A. , Trekhlebov A. S. , Andronov V. G. 
Published: November 2024

The purpose of the research analysis of known invasive and non-invasive examination methods, determination of the necessary criteria for assessing the degree of fatigue of submariners, a survey of Navy personnel involved in service on submarine ships was conducted, on the basis of which a justification of research directions was carried out for the subsequent development of a system for collecting, evaluating and analyzing the physiological state and factors affecting the fatigue of military personnel.Methods: the use of an experimental non-invasive research method to determine the degree of fatigue and physiological condition of submariners based on three criteria during the month, the analysis of the results obtained, the establishment of a comparative analysis method during the development, a structural analysis of the system based on previously known devices and sensors.Results. The dependence of the studied indicators on the time of watch keeping and their connection with the increase in fatigue were found. It has been established that in order to develop a system for monitoring the fatigue of submariners, a systematic analysis and objective assessment should be carried out, including: determination of methods for monitoring the condition of military personnel; application of knowledge from medicine, physiology, biophysics, biomechanics, bioengineering, electronics, circuitry and programming, to develop effective methods for monitoring physical condition and fatigue. Based on the analysis of domestic and foreign techniques and devices, a proprietary method for implementing a system for collecting assessments, analyzing the physiological state and factors affecting the fatigue of military personnel is proposed.Conclusion. It is concluded that it is necessary to conduct non-invasive studies of the degree of fatigue, before proposing the development and proposal of its own device and methodology for assessing the degree of fatigue, capable of implementing individual features of the system for operational monitoring in order to improve combat readiness, situational awareness, health, safety, mobility of submariners.The development of such monitoring systems and devices is necessary in the modern world to prevent or prevent disasters without reducing the efficiency of submariners.
Design and multidimensional analysis of dental orthopedic prosthetics quality
Authors: Maslak A. A. , Arutyunov A. S. , Grachev D. I. , Muslov S. A. 
Published: November 2024

The purpose of the research is a multidimensional analysis of the "quality of life" of patients before and after dental prosthetics. It is necessary to assess the quality of life of patients after prosthetics, depending on the type of prostheses, gender, and age of patients and give recommendations on the choice of prosthetics method. Methods. Dental prosthetics was performed at the clinic of the Moscow State Medical University named after A. I. Evdokimov, four types of prostheses were tested - the classic traditional prosthesis (TR) and three types of digital prostheses (D1, D2, D3). Based on the developed OHIP-20 DG questionnaire, the quality of life of patients was assessed before prosthetics, immediately after prosthetics and six months later. The quality of life of patients after prosthetics was determined within the framework of the theory of latent variables. Using a four-factor analysis of variance, the impact on the quality of life of the type of prostheses, the duration of adaptation after prosthetics, gender and age of patients was assessed. Results. Within the framework of the theory of latent variables, it is shown that the developed questionnaire can be used as a measuring tool to analyze the influence of the studied factors on the quality of life of patients after prosthetics. Due to the use of four-factor analysis of variance, the accuracy of statistical analysis has been improved and the statistical significance of four sources of variance has been revealed. Based on the results of statistical analysis, recommendations on the choice of prosthetics method have been developed. Conclusion. A multidimensional analysis of the studied factors affecting the quality of life of patients after dental prosthetics was carried out. The quality of life of patients increases statistically significantly after prosthetics. Due to the use of a four-factor model of variance analysis, the precision of assessments of the quality of life of patients has been improved. The prosthetics method (D1) is recommended for women, the prosthetics method (D3) is recommended for men. The obtained results are recommended to be used in practice.
Application of mathematical models in predicting drug dosage and its efficacy
Authors: Tufik Shehine Mohamad , Nikolaos Tzenios , Zavidovskaya K. V. , Lazurina L. P. , Dotsenko Yu. M. 
Published: November 2024

The purpose of the research is to form a comprehensive understanding of how mathematical models are used to interpret complex dynamics related to the distribution, metabolism and excretion of drugs in the human body. The use of mathematical models to predict the required dose of drug prescriptions and establish its effectiveness means a paradigm shift in the field of pharmacology.Methods. The methodology used in this study was aimed at identifying and analytically reviewing articles that correspond to the objectives of the study. The publications included in the analysis were analyzed and data extracted, focusing on key information such as the mathematical modeling methodology used, the exact predicted treatment effects, the populations studied, long-term prognostic effects, and the assessment of the use of various drug dosing regimens.Results. In total, 12 publications were analyzed, which used four different methodologies: models with the effects of several different conditions, models that take into account the occurrence of various discrete events, models based on the effects of informative signs taking into account the physiology of individuals, as well as survival models and generalized linear models.Conclusion. The conducted study of the current state of mathematical modeling in medical research for the purpose of comparative effectiveness is intended for practicing scientists and doctors in conducting further research and introducing innovations. Despite the challenges, the potential impact of these models aimed at bridging the gap between the controlled clinical environment and the real health context is undeniable. The use of mathematical modeling methods to predict the dosage of medicines will improve the quality and effectiveness of personalized medical appointments in the coming years.
Investigation of the influence of linear and angular deviations of UAVS on the change in parallaxes of images of the underlying surface obtained in the mode of rectilinear horizontal flight
Authors: Andronov V. G. , Chuev A. A. 
Published: November 2024

The purpose of the research is assessment of the joint and separate influence of linear and angular deviations of the UAV from the trajectory of rectilinear horizontal flight on the change in parallax images of the underlying surface. Methods. Quantitative estimates are based on a study of the sensitivity of a model describing the functional relationship between the parameters of UAV deviations from a given trajectory and changes in the longitudinal and transverse parallaxes of overlapping images of the underlying surface caused by these deviations.Results. The difference of longitudinal parallaxes in the absence of linear deviations of the UAV, regardless of the sign of the ordinate of the point in the overlap zone, is always positive and increases with an increase in the level of angular deviations, and transverse deviations are negative and decrease, and the value of the first is three times greater than the second. The difference of the transverse parallaxes in the absence of angular deviations of the UAV at a positive ordinate point in the overlap zone is positive, and the longitudinal parallaxes are negative, and at a negative ordinate, on the contrary. At the same time, regardless of the sign of the ordinate of the point in the overlap zone, with an increase in the level of linear deviations of the UAV, the first increases, the second decreases, and the value of the first is four times greater than the secon.Conclusion. The magnitude of the parallax differences depends on the levels of linear and angular deviations of the UAV that occurred at the time of registration of the inclined image, and the sign depends on the sign of the ordinate of the corresponding point in the overlap zone of the second pair of images. In this case, the difference of longitudinal parallaxes is always directly proportional to the level of angular deviations and inversely proportional to the level of linear deviations, and transverse parallaxes is directly proportional to the level of angular deviations at negative values of the ordinate of the point and inversely proportional at its positive values.
Decoding the Digital Pulse: Bibliometric Analysis of 25 Years in Digital Health Research Through the Journal of Medical Internet Research
Authors: Kaczmarczyk Robert , Wilhelm Theresa Isabelle , Roos Jonas , Martin Ron 
Published: November 2024

Background
As the digital health landscape continues to evolve, analyzing the progress and direction of the field can yield valuable insights. The Journal of Medical Internet Research (JMIR) has been at the forefront of disseminating digital health research since 1999. A comprehensive network analysis of JMIR publications can help illuminate the evolution and trends in digital medicine over the past 25 years.

Objective
This study aims to conduct a detailed network analysis of JMIR’s publications to uncover the growth patterns, dominant themes, and potential future trajectories in digital health research.

Methods
We retrieved 8068 JMIR papers from PubMed using the Biopython library. Keyword metrics were assessed using accuracy, recall, and F1-scores to evaluate the effectiveness of keyword identification from Claude 3 Opus and Gemini 1.5 Pro in addition to 2 conventional natural language processing methods using key bidirectional encoder representations from transformers. Future trends for 2024-2026 were predicted using Claude 3 Opus, Google’s Time Series Foundation Model, autoregressive integrated moving average, exponential smoothing, and Prophet. Network visualization techniques were used to represent and analyze the complex relationships between collaborating countries, paper types, and keyword co-occurrence.

Results
JMIR’s publication volume showed consistent growth, with a peak in 2020. The United States dominated country contributions, with China showing a notable increase in recent years. Keyword analysis from 1999 to 2023 showed significant thematic shifts, from an early internet and digital health focus to the dominance of COVID-19 and advanced technologies such as machine learning. Predictions for 2024-2026 suggest an increased focus on artificial intelligence, digital health, and mental health.

Conclusions
Network analysis of JMIR publications provides a macroscopic view of the evolution of the digital health field. The journal’s trajectory reflects broader technological advances and shifting research priorities, including the impact of the COVID-19 pandemic. The predicted trends underscore the growing importance of computational technology in future health care research and practice. The findings from JMIR provide a glimpse into the future of digital medicine, suggesting a robust integration of artificial intelligence and continued emphasis on mental health in the postpandemic era.
Nurses’ and Nursing Assistants’ Experiences With Teleconsultation in Small Rural Long-Term Care Facilities: Semistructured Interview Pilot Study
Authors: Nabelsi Veronique , Leclerc Marie Chantal , Plouffe Véronique 
Published: November 2024

Background
In Quebec, the shortage of nurses during night shifts compromises the safety and quality of resident care, particularly in small residential and long-term care centers (“Centres d’hébergement et de soins de longue durée”; CHSLDs) located in rural areas. The need to ensure the continuous presence of nurses 24 hours a day in CHSLDs has become more pressing, forcing some facilities to implement exceptional measures such as on-call telephone services to ensure access to a nurse. In light of these challenging circumstances, the Direction nationale des soins et des services infirmiers of Quebec’s Ministère de la Santé et des Services sociaux has rolled out a teleconsultation pilot project.

Objective
This study aims to explore nurses’ and nursing assistants’ experience of integrating teleconsultation during night shifts in rural CHSLDs with ≤50 residents.

Methods
The 6-month pilot project was rolled out sequentially in 3 rural CHSLDs located in 2 administrative regions of Quebec between July 2022 and March 2023. A total of 18 semistructured interviews were conducted with 9 nurses and nursing assistants between February and July 2023.

Results
Participants’ experiences revealed that teleconsultation provided significant added value by improving clinical, administrative, and organizational practices. Some practices remained unchanged, indicating stable workflows. Workflow optimization through an expanded scope of practice ensured efficient and safe continuity of care. Enhanced collaboration between nurses and nursing assistants led to improved care coordination and communication. The leadership played a significant role in clarifying professionals’ roles and in supporting effective adaptation to teleconsultation.

Conclusions
This pilot project represents a significant step forward in improving care for CHSLD residents in Quebec. Teleconsultation not only makes it possible to overcome recruitment challenges and ensure the continuous presence of nurses during night shifts but also optimizes professional practices while ensuring the safety and quality of care provided to residents.
Evaluation of ethanolic extract of Piper methysticum leaves on anxiolytic activity of mice
Authors: Shallvi Dr , Malhotra Meenakshi , Saruchi Dr , Singh Ajeet Pal , Singh Amar Pal 
Published: November 2024

The ethanol extract of Piper methysticum, commonly known as kava, has shown promising results in reducing anxiety. Studies suggest it may have anxiolytic effects, potentially offering a natural alternative to conventional anxiety treatments. The ethanolic extract of Piper methysticum can increase the duration of action. It can also increase the time spent in open arm, entry in open arm (in elevated plus model) as well as increase the time spent in light field (in Light Dark field) thus we can conclude that it can also possesses Anxiolytic action. The ethanolic extract of Piper methysticum possesses an anxiolytic like activity without sedative side effect. The corticosterone level in mice is increased when they got anxiety. So when the plasma corticosterone level of mice is checked in control group its turn out to be 10.28±0.52. It gets decreased with increase in doses. When treated with low dose of Aqueous extract is 7.28±1.44 is less effective than low dose of Ethanolic extract that is 6.22±1.28. Same as that high dose of extract shows the corticosterone level was 6.24±2.28 which was also less effective than high dose of ethanolic extract which was 5.52±0.32. Most effectively stress was decreased when treated with the Standard drug (Alprazolam) which shows plasma corticosterone level was 1.24±0.36. The mice of Piper methysticum extract (300 &600 mg/kg/ p.o.) treated group showed significantly (p<0.05) increased in body water intake as compared to the control group. Results showed that synthesized extract is very effective for the treatment of anxiety.
Keywords: Piper methysticum; anxiolytic activity; Anthraquinones; Light Dark model
Consequences of a Two-Tiered Regulatory Model: Evidence from Audit Fees and Changes in Foreign Private Issuer Status
Authors: Burnett Brian M. , Jørgensen Bjørn N. , Pollard Troy J. 
Published: November 2024

SUMMARY
The U.S. SEC permits exemptions from U.S. domestic securities regulation for foreign-domiciled firms that qualify as foreign private issuers (FPIs). We study the impact on audit fees when foreign-domiciled firms lose or gain FPI status for a plausibly exogenous reason while maintaining their cross-listing status. After losing FPI status, foreign firms must comply with corporate governance, financial statement reporting, and insider trading disclosure requirements of U.S. domestic issuers. We find that FPI status is associated with lower cross-listing costs, as evidenced by significant audit fee increases when firms lose FPI status. Notably, we find that the benefit of FPI status is more pronounced among firms from countries with robust governance standards. Conversely, for firms from countries with weaker governance standards, compliance with U.S. corporate governance requirements correlates with reduced audit fees, offsetting increased audit fees arising from compliance with financial statement requirements and insider information disclosure.
JEL Classifications: M41; M42; M48.
Internal and External Social Capital of Big 4 Audit Offices
Authors: Cardinaels Eddy , Khoo Eunice S. , Kuang Yu Flora , Lee Gladys , Qin Bo 
Published: November 2024

SUMMARY
This study investigates the impact of social capital within and outside Big 4 audit offices on audit quality. We find that higher levels of internal and external social capital correlate with improved audit quality, indicating that social capital functions as a bond and a bridge in enhancing auditor performance. Additional analysis suggests that audit-office social capital also helps enhance audit efficiency. Furthermore, we examine the interaction between internal and external social capital, revealing that increased external social capital in audit offices with strong internal social capital is associated with higher audit quality. Our research provides valuable insights for audit offices aiming to optimize their performance outcomes effectively.
Data Availability: Data are available from the public sources cited in the text.
JEL Classifications: M42.
Submit-to-Accept Times in Accounting: Determinants and Comparisons to Other Business Disciplines
Authors: Hurley Patrick J. , Gal-Or Ronen , Knechel W. Robert , Pesch Heather L. 
Published: November 2024

ABSTRACT
We use hand-collected data to analyze submission-to-acceptance (STA) times in the top-tier accounting journals relative to other top-tier business journals from 1993 through 2021. We find that, vis-à-vis other business disciplines, STA times at top-tier accounting journals were shorter in the first half of our sample period and significantly longer thereafter. We also observe shorter STA times for articles with authors from more highly ranked institutions; this effect exists only in top-tier accounting journals and has increased over time. In additional analyses, we find that our primary inferences are unchanged when considering maturity of initial journal submissions, journal-level democratization, and review process improvements related to paper quality. Our results should be of interest to researchers, journal editors, reviewers, provosts, deans, and tenure and promotion committees.
Data Availability: The data used in this study are available from the sources indicated herein.
Do Information Processing Costs Matter to Regulators? Evidence from U.S. Mortgage Companies’ Supervision
Authors: Even-Tov Omri , Su Andy , Wang K. Philip 
Published: November 2024

ABSTRACT
We examine the impact of reducing information processing costs on U.S. state regulators who supervise mortgage companies. State regulators traditionally disclosed enforcement actions only on their individual websites. A centralized repository, introduced in 2012, assembled enforcement records across states in one place, reducing a regulator’s cost to learn about enforcements in other states. Using a difference-in-differences design, we find that enforcement records posted on the centralized repository significantly increase the probability of subsequent enforcement actions against the same firm in other states. This suggests that reducing information processing costs helps state regulators identify companies engaging in misconduct. This effect is stronger for records from state websites where information is harder to process and for state regulators with more limited resources. Last, we observe that sanctioned lenders reduce the credit supply in other states after their enforcement records in one state are posted on the centralized repository.
JEL Classifications: G21; G18; K2; M4.