bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Pacific SSTs in improving reconstructed streamflow over the coterminous US
Authors: Mukhopadhyay Sudarshana , Patskoski Jason M. , Sankarasubramanian A. 
Published: March 2018

AbstractReconstructed annual streamflows using tree-ring chronologies provide useful information on moisture availability during the pre-historic period, but they have limitations in estimating high flows due to the upper bound on soil water holding capacity and trees’ metabolic growth limits. We propose a hybrid approach that uses tree-ring chronologies and climatic indices for improving high flows in 301 basins whose annual streamflows are modulated by ENSO and/or PDO. The hybrid decomposition approach relies on separating the moisture supply into the basin as outside-the-region moisture and within-the-region moisture with the former being estimated by SST indices and the latter being estimated by tree-ring chronologies. Analyses over the 301 stations from coterminous US show that the proposed approach improves the high flows and improves the overall error in the reconstructed streamflows. Potential utility of the improved reconstructed annual streamflows with improved high flows is also discussed.
Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells
Authors: Silva Luciane M. , Jacobs Damon T. , Allard Bailey A. , Fields Timothy A. , Sharma Madhulika , Wallace Darren P. , Tran Pamela V. 
Published: March 2018

AbstractAutosomal Dominant Polycystic Kidney Disease (ADPKD) is caused by mutation of PKD1 or PKD2, which encode polycystin 1 and 2, respectively. The polycystins localize to primary cilia and the functional loss of the polycystin complex leads to the formation and progressive growth of fluid-filled cysts in the kidney. The pathogenesis of ADPKD is complex and molecular mechanisms connecting ciliary dysfunction to renal cystogenesis are unclear. Primary cilia mediate Hedgehog signaling, which modulates cell proliferation and differentiation in a tissue-dependent manner. Previously, we showed that Hedgehog signaling was increased in cystic kidneys of several PKD mouse models and that Hedgehog inhibition prevented cyst formation in embryonic PKD mouse kidneys treated with cAMP. Here, we show that in human ADPKD tissue, Hedgehog target and activator, Glioma 1, was elevated and localized to cyst-lining epithelial cells and to interstitial cells, suggesting increased autocrine and paracrine Hedgehog signaling in ADPKD, respectively. Further, Hedgehog inhibitors reduced basal and cAMP-induced proliferation of ADPKD cells and cyst formation in vitro. These data suggest that Hedgehog signaling is increased in human ADPKD and that suppression of Hedgehog signaling can counter cellular processes that promote cyst growth in vitro.
Cervical microbiome is altered in cervical intraepithelial neoplasia after loop electrosurgical excision procedure in china
Authors: Zhang Hongwei , Lu Jiaqi , Lu Yingying , Cai Qingqing , Liu Haiou , Xu Congjian 
Published: March 2018

AbstractAlthough human papillomavirus (HPV) infection is a major cause leading to the development of cervical intraepithelial neoplasia (CIN), the relationship between genital microbiome and HPV persistence/clearance is not well established. Loop electrosurgical excision procedure (LEEP) is one of standard treatments of CIN 2/3 globally, yet little is known about how the LEEP influence genital microbiota. We conducted a prospective study of 26 patients with CIN2/3 who underwent analysis of cervical microbiome before and after 3 months of LEEP treatment. Cervical swabs were collected, and microbiomes were analyzed by 16S ribosomal RNA gene sequencing. A decrease of cervical microbial diversity was observed after 3 months of LEEP treatment. Notably, a significant shift from community type of a Prevotella-containing and lack of a consistent dominant species to lactobacillus iners dominated microbiome correlated with LEEP. Particularly, Leptotrichia and clostridium were further decreased after LEEP treatment (P = 0.049 and P = 0.002, respectively). Our results suggest that the cervical microbiome is altered after LEEP treatment in patients with CIN2/3. Further studies with larger sample sizes are needed to validate these findings.
Evolution of the anti-truncated stellar profiles of S0 galaxies since z = 0.6 in the SHARDS survey
Authors: Borlaff Alejandro , Eliche-Moral M. Carmen , Beckman John E. , Vazdekis Alexandre , Lumbreras-Calle Alejandro , Ciambur Bogdan C. , Pérez-González Pablo G. , Cardiel Nicolás , Barro Guillermo , Cava Antonio 
Published: March 2018

Context. Anti-truncated lenticular galaxies (Type-III S0s) present tight scaling relations between their surface brightness photometric and structural parameters. Although several evolutionary models have been proposed for the formation of these structures, the observations of Type-III S0 galaxies are usually limited to the local Universe.
Aims. We aim to compare the properties of Type-III discs in a sample of S0 galaxies at 0.2 < z < 0.6 with those of the local Universe. In this paper, we study the evolution of the photometric and structural scaling relations measured in the rest-frame R-band with z and the possible differences between the rest-frame (B − R) colours of the inner and outer disc profiles.
Methods. We make use of a sample of 14 Type-III E/S0–S0 galaxies at 0.2 < z < 0.6 from the GOODS-N field identified and characterised in a previous paper. We study whether or not the correlations found in local Type-III S0 galaxies were present ~6 Gyr ago. We analyse the distribution of the surface brightness characteristic parameters (Rbreak, μbreak, hi, ho, μ0,i and μ0,o) as a function of the stellar mass and look to see if there is a significant change with z. We also derive their rest-frame (B − R) colour profiles. Finally, we compare these results with the predictions from a grid of SSP models.
Results. We find that the inner and outer scale-lengths of Type-III S0 galaxies at 0.4 < z < 0.6 follow compatible trends and scaling relations with those observed in local S0 galaxies as a function of the break radius, Rbreak. We do not detect any significant differences between the location of Rbreak between z ~ 0.6 and z ~ 0 for a fixed stellar mass of the object, whereas the surface brightness at the break radius μbreak is ~1.5 mag arcsec-2 dimmer in the local Universe than at z ~ 0.6 for a fixed stellar mass. We find no significant differences in the (B − R) colour between the inner and outer profiles of the Type-III S0 galaxies at 0.2 < z < 0.6.
Conclusions. In contrast to Type-II (down-bending) profiles, the anti-truncated surface brightness profiles of S0 galaxies present compatible Rbreak values and scaling relations during the last 6 Gyr. This result and the similarity of the colours of the inner and outer discs point to a highly scalable and stable formation process, probably more related to gravitational and dynamical processes than to the evolution of stellar populations.
Evidenzbasierte Klinische Sozialarbeit: Gegenstand und Perspektiven
Authors: Deimel Daniel 
Published: March 2018

ZusammenfassungKlinische Sozialarbeit hat sich in den letzten 15 Jahren als gesundheitsspezifische Profession in Deutschland etabliert. Sie bezieht sich auf ein bio-psycho-soziales Gesundheitsverständnis und arbeitet insbesondere mit schwer erreichbaren Klientengruppen. Das Konzept der Evidenzbasierung wird in Teilen der Profession und Disziplin Sozialer Arbeit kritisiert und abgelehnt. In dem Beitrag werden die Konzepte der Evidenzbasierung und der Klinischen Sozialarbeit in Verbindung gebracht und aufgezeigt, welchen Nutzen in einer evidenzbasierten Klinischen Sozialarbeit für die klinische Praxis und Professionsentwicklung beinhaltet.
Die Harmonisierung platonischer und aristotelischer Ontologie im
neuplatonischen Kategorienkommentar
Authors: Welt Thomas 
Published: March 2018

Zusammenfassung
Commentaries on Plato’s and Aristotle’s works were central to the Neoplatonic
school’s curriculum. In a fixed order, established since Jamblichus, the
Aristotelian writings were first read, then the Platonic ones. At the beginning,
the logical writings of Aristotle and particularly his
Categories were examined. But like any other work, the
Categories were construed from the perspective of
Neoplatonic anagogy. In addition, the commentator was obliged to work out the
commonalities between the two philosophical teachings. That anagogical and
harmonising approach culminates in the commentaries on the
Categories with the integration of the Aristotelian concept
of substance into the Platonic concept of ideas. While Dexippus is primarily
engaged in the right modes of predication corresponding to the sensible and the
intelligible realm respectively, Simplicius focuses on the description of a
continuous connection of being.
CV reduplication in Isbukun Bunun
Authors: Lin Hui-shan 
Published: March 2018

Abstract
This paper presents a novel generalization of the reduplicant (henceforth red) placement in CV reduplication in Isbukun Bunun. It is shown that the variable red placements cannot be explained in terms of the presence of a PF marker or merely by the syllable number of the root, as assumed in previous studies. Rather, the variable red placements are argued to be simultaneously governed by the size and the syllable well-formedness of the root. The red is normally prefixed to the root; however, if onsetless red is generated under normal copying, the placement of the red shifts one syllable rightward, except for shorter (bimoraic) roots. Thus, the variable placements of the red are driven by a universal tendency for the red to be unmarked and the need for the P-Root to sustain a minimal size.
NP interpretation and disposal variations among the Mandarin, Cantonese, and Shaoxing dialects
Authors: Yao Jennifer Shuiying 
Published: March 2018

Abstract
Corresponding to the Ba construction (S Ba-OVC) in Mandarin, Cantonese prefers a strong SVCO word order, and the Shaoxing dialect adopts an SOVC variation. This paper makes a detailed cross-linguistic study on the structure and semantic interpretations of disposal NPs and highlights the role of the disposal NPs in the formation of disposal construction in the above three dialects. It suggests that the word order variations in disposal constructions among the Mandarin, Cantonese, and Shaoxing dialects result from the different options being adopted to make the object NPs conform to the so called definiteness constraint of a disposal NP, namely, definite, specific, or generic.
Exploring the emergence of the postverbal sin1
先 in Cantonese
Authors: Zhou Yang 
Published: March 2018

Abstract

Sin1
先 as a function word in contemporary Cantonese encodes a number of grammatical and pragmatic meanings. As its most prominent feature in syntax, it predominantly occurs in the postverbal position while indicating the meaning of ‘first’. This paper explores the emergence of the postverbal sin1
先 ‘first’ in Cantonese. We first examine the word order typology on the element for ‘first’ in the languages and dialects of southern coastal China. In this linguistic area, the postverbal elements for ‘first’ in Chinese dialects are contact-induced by Tai-Kadai and Hmong-Mien languages; whereas sin1
先 ‘first’ in the mainstream Cantonese shows a stronger tendency to be placed in the postverbal position than its counterparts in other Chinese dialects. We then discuss the word order and semantic changes of sin1
先 from 1820s to 1960s based on Cantonese historical materials. Besides the pressure of language contact, the formation of the postverbal sin1
先 ‘first’ has been further triggered by the semantic motivation to formally differentiate the ‘precedent-subsequent’ polysemy within sin1
先 itself. In short, the emergence of the postverbal sin1
先 ‘first’ in Cantonese has been a two-stage process, dually driven by external and internal causes, respectively.
The working class left behind? The class gap in life satisfaction in Germany and Switzerland over the last decades
Authors: Lipps Oliver , Oesch Daniel 
Published: March 2018

ABSTRACT
The 1990s and 2000s were a gloomy period for Germany’s working class, hit by mass unemployment, welfare retrenchment and wage stagnation. We examine whether the growing economic disparity between the top and the bottom of Germany’s class structure was accompanied by a widening class gap in life satisfaction. We analyse whether there is a social class gradient in life satisfaction and whether, over the last decades, this class gradient increased in Germany, relative to the comparison case of Switzerland. We use panel data for Germany (1984–2014) and Switzerland (2000–2015) and check the robustness of our results by replicating our analysis with the pooled German and Swiss samples of the European Social Survey (2002–2014). In both countries, respondents in higher classes report substantially higher life satisfaction than those in lower classes. The class gap is twice as large in Germany than in Switzerland. In Germany, the class gap in life satisfaction narrowed between 1984 and 1990, strongly widened between 1990 and 2005 and then decreased again after 2010. In Switzerland, the class gap did not follow a clear time trend, but remained basically constant. In Germany, differences in unemployment risks and household income account for half of the class gap and its evolution over time.
Identification of hand motion using background subtraction method and extraction of image binary with backpropagation neural network on skeleton model
Authors: Fauziah  , Wibowo E P , Madenda S , Hustinawati  
Published: March 2018

Abstract
Capturing and recording motion in human is mostly done with the aim for sports, health, animation films, criminality, and robotic applications. In this study combined background subtraction and back propagation neural network. This purpose to produce, find similarity movement. The acquisition process using 8 MP resolution camera MP4 format, duration 48 seconds, 30frame/rate. video extracted produced 1444 pieces and results hand motion identification process. Phase of image processing performed is segmentation process, feature extraction, identification. Segmentation using bakground subtraction, extracted feature basically used to distinguish between one object to another object. Feature extraction performed by using motion based morfology analysis based on 7 invariant moment producing four different classes motion: no object, hand down, hand-to-side and hands-up. Identification process used to recognize of hand movement using seven inputs. Testing and training with a variety of parameters tested, it appears that architecture provides the highest accuracy in one hundred hidden neural network. The architecture is used propagate the input value of the system implementation process into the user interface. The result of the identification of the type of the human movement has been clone to produce the highest acuracy of 98.5447%. The training process is done to get the best results.
SCRAM: a pipeline for fast index-free small RNA read alignment and visualization
Authors: Fletcher Stephen J , Boden Mikael , Mitter Neena , Carroll Bernard J 
Published: March 2018

AbstractSummarySmall RNAs play key roles in gene regulation, defense against viral pathogens and maintenance of genome stability, though many aspects of their biogenesis and function remain to be elucidated. SCRAM (Small Complementary RNA Mapper) is a novel, simple-to-use short read aligner and visualization suite that enhances exploration of small RNA datasets.Availability and implementationThe SCRAM pipeline is implemented in Go and Python, and is freely available under MIT license. Source code, multiplatform binaries and a Docker image can be accessed via https://sfletc.github.io/scram/.Supplementary informationSupplementary data are available at Bioinformatics online.
GenomeDISCO: a concordance score for chromosome conformation capture experiments using random walks on contact map graphs
Authors: Ursu Oana , Boley Nathan , Taranova Maryna , Wang Y X Rachel , Yardimci Galip Gurkan , Stafford Noble William , Kundaje Anshul 
Published: March 2018

Abstract

Motivation
The three-dimensional organization of chromatin plays a critical role in gene regulation and disease. High-throughput chromosome conformation capture experiments such as Hi-C are used to obtain genome-wide maps of three-dimensional chromatin contacts. However, robust estimation of data quality and systematic comparison of these contact maps is challenging due to the multi-scale, hierarchical structure of chromatin contacts and the resulting properties of experimental noise in the data. Measuring concordance of contact maps is important for assessing reproducibility of replicate experiments and for modeling variation between different cellular contexts.

Results
We introduce a concordance measure called DIfferences between Smoothed COntact maps (GenomeDISCO) for assessing the similarity of a pair of contact maps obtained from chromosome conformation capture experiments. The key idea is to smooth contact maps using random walks on the contact map graph, before estimating concordance. We use simulated datasets to benchmark GenomeDISCO's sensitivity to different types of noise that affect chromatin contact maps. When applied to a large collection of Hi-C datasets, GenomeDISCO accurately distinguishes biological replicates from samples obtained from different cell types. GenomeDISCO also generalizes to other chromosome conformation capture assays, such as HiChIP.

Availability and implementation
Software implementing GenomeDISCO is available at https://github.com/kundajelab/genomedisco.

Supplementary information
Supplementary data are available at Bioinformatics online.
Extended state observer-based back-stepping control for hypersonic reentry vehicle with input constraints
Authors: Chen Chen , Ma Guangfu , Lyu Yueyong , Guo Yanning 
Published: March 2018

Abstract
This paper investigates the attitude-tracking control problem of hypersonic reentry vehicle in cases of multiple uncertainties, external disturbances and input constraints. The controller design is based on synthesizing the extended state observer (ESO) into a back-stepping control technique. This control-oriented model is formulated with mismatched and matched uncertainties. They reflect the total disturbances that group different types of aerodynamic uncertainties and external moment disturbances. In order to improve the system robustness, a sigmoid function-based ESO is first proposed. This will estimate the total disturbance and is equipped with a controller. The sigmoid smooth function is also introduced for the purpose of handling the input constraints. This will approximate saturation and guarantee that the control input is bounded. Error states between the actual control input and the desired control input are integrated to compensate for the saturation effect. Following this, the stability of the closed-loop system is proved within the Lyapunov theory framework. Several simulations are then investigated to illustrate the effectiveness of the proposed constrained attitude control scheme.
Solving polynomial systems via homotopy continuation and monodromy
Authors: Duff Timothy , Hill Cvetelina , Jensen Anders , Lee Kisun , Leykin Anton , Sommars Jeff 
Published: March 2018

Abstract
We study methods for finding the solution set of a generic system in a family of polynomial systems with parametric coefficients. We present a framework for describing monodromy-based solvers in terms of decorated graphs. Under the theoretical . that monodromy actions are generated uniformly, we show that the expected number of homotopy paths tracked by an algorithm following this framework is linear in the number of solutions. We demonstrate that our software implementation is competitive with the existing state-of-the-art methods implemented in other software packages.
Beyond Acculturation: Multiculturalism and the Institutional Shaping of an Ethnic Consumer Subject
Authors: Veresiu Ela , Giesler Markus 
Published: March 2018

Abstract
Prior consumer research has investigated the consumer behavior, identity work, and sources of ethnic group conflict among various immigrants and indigenes. However, by continuing to focus on consumers’ lived experiences, researchers lack theoretical clarity on the institutional shaping of these individuals as ethnic consumers, which has important implications for sustaining neocolonial power imbalances between colonized (immigrant-sending) and colonizing (immigrant-receiving) cultures. We bring sociological theories of neoliberal governmentality and multiculturalism to bear on an in-depth analysis of the contemporary Canadian marketplace to reveal our concept of market-mediated multiculturation, which we define as an institutional mechanism for attenuating ethnic group conflicts through which immigrant-receiving cultures fetishize strangers and their strangeness in their commodification of differences, and the existence of inequalities between ethnicities is occluded. Specifically, our findings unpack four interrelated consumer socialization strategies (envisioning, exemplifying, equipping, and embodying) through which institutional actors across different fields (politics, market research, retail, and consumption) shape an ethnic consumer subject. We conclude with a critical discussion of extant scholarship on consumer acculturation as being complicit in sustaining entrenched colonialist biases.
Breast Cancer Screening: Evidence and Recommendations
Authors: Wernli Karen J. , Bowles Erin J. 
Published: March 2018

Abstract
Breast cancer screening in the United States was first recommended to women in 1976. Over the past decade, mammography screening has changed from film screen mammography to primarily digital mammography, which, as of 2016, accounts for over 97% of all mammograms performed in the United States. Several systematic reviews, which have included results from up to 9 randomized clinical trials from the United States, Europe, and Canada, have demonstrated a reduced risk of breast cancer mortality associated with breast cancer screening. Potential harms from breast cancer screening include false-positive mammograms (which may lead to unnecessary additional imaging and benign breast biopsies), overdiagnosis, and radiation exposure. This chapter summarizes evidence from randomized controlled trials for mortality benefit; current society and task force recommendations for mammography screening; evaluation of the evidence; risk–benefit analysis; and supplemental screening in high-risk women.
Breast Cancer Metastatic Imaging
Authors: McDonald Elizabeth S. , Elmi Azadeh , Mankoff David A. 
Published: March 2018

Abstract
This chapter reviews appropriate indications for advanced imaging, such as PET/CT, in the evaluation of breast cancer. An informed imaging approach is based on primary tumor size and pathological characteristics, as well as patient symptoms that may indicate a higher likelihood of metastatic disease. When evaluation for metastatic disease is indicated, survey imaging with CT, bone scintigraphy, abdominal MRI, brain MRI, and/or PET/CT can be used to establish disease burden, and to identify a biopsy target for pathological confirmation. We emphasize the evolving role of FDG PET/CT in this chapter, including basic principles of PET imaging, followed by a short section on image interpretation. Finally, the concept of using imaging as a response biomarker is introduced.