bluuebunny/crossref_metadata_2025_split huggingface dataset:
Facial Artery as a Recipient Vessel for Extensive Scalp Reconstruction With Free Omental Flap Without Vein Graft
Authors: Kim Jin Woo , Woo Soo Hyun , Jang Suk Yoon , Kim Woo Seob , Bae Tae Hui , Kim Han Koo 
Published: February 2018

Abstract
Most patients with reconstruction for extensive scalp defects require the use of a free flap. The suitability of the recipient vessel has a major impact on the surgery and postoperative outcome. Flaps that can be used to reconstruct the total scalp with a single flap include the latissimus dorsi (LD) and omental flaps; the LD flap is generally preferred since the omental flap results in relatively larger donor site morbidity. The recipient vessel most commonly used for scalp defect reconstruction is the superficial temporal vessel. The authors report a patient with successful total scalp reconstruction using a free omental flap on a patient whose bilateral superficial temporal arteries could not be used and who did not have available LD on both sides due to previous LD free flap surgeries for recurrent scalp angiosarcoma. In this patient, direct anastomosis of the flap to the right facial artery was performed without pedicle lengthening, such as vein graft or arteriovenous loops, and favorable outcome was achieved in terms of facial contour after recovery. The free omental flap is useful for reconstruction of extensive scalp defects without additional complex surgical procedures when other flaps are not viable or when the recipient vessel is located at a far distance.
The Effect of Electroconvulsive Therapy on Hypoperfusion in Psychotic Bipolar Depression
Authors: De Smet Céline Julie , Sabbe Bernard , Oldenburg J.F.E. 
Published: February 2018

Abstract
The pharmacological treatment of bipolar depression has low response rates. Twenty percent to 30% of patients have an insufficient response to medication. The guidelines suggest that electroconvulsive therapy (ECT) is the next step. The aim of this case study is to evaluate the effect of ECT on the perfusion of the brain in bipolar depression, while monitoring effects on mood and cognition. We present a case study of 56-year-old female patient who suffered from a psychotic depression and cognitive impairment. Before ECT, she took several antidepressants and atypical antipsychotics, but there was no improvement in her symptoms. By using single-photon emission computed tomography, we obtained the status of the regional cerebral blood flow and found a decreased perfusion in the anterior part of the left temporal lobe, the posterior part of the right temporal lobe, and in the left gyrus frontalis inferior. This is consistent with previous findings. Electroconvulsive therapy resulted in a resolution of the patient's depression and an improvement in her neurocognitive performance. Markedly, this was only in visual learning and working memory, domains in which the patient was already relatively stronger pre-ECT treatment. A new single-photon emission computed tomography, 4 weeks after the last ECT course, showed normalization of the regional cerebral blood flow.
Frequency selective encoding of substrate vibrations in the somatosensory cortex
Authors: Prsa Mario , Huber Daniel 
Published: February 2018

AbstractSensing vibrations that propagate through solid substrates conveys fundamental information about moving objects and other nearby dynamic events. Here we report that neurons responsive to substrate vibrations applied to the mouse forelimb reveal a new way of representing frequency information in the primary somatosensory cortex (S1). In contrast to vibrotactile stimulation of primate glabrous skin, which produces temporally entrained spiking and frequency independent firing rates, we found that mouse S1 neurons rely on a different coding scheme: their spike rates are conspicuously tuned to a preferred frequency of the stimulus. Histology, peripheral nerve block and optogenetic tagging experiments furthermore reveal that these responses are associated with the activation of mechanoreceptors located in deep subdermal tissue of the distal forelimb. We conclude that the encoding of frequency information of substrate-borne vibrations in the mouse S1 might be analogous to the representation of pitch of airborne sound in auditory cortex.
Competence Inhibition by the XrpA Peptide Encoded Within thecomXGene ofStreptococcus mutans
Authors: Kaspar Justin , Shields Robert C. , Burne Robert A. 
Published: February 2018

SUMMARYStreptococcus mutansdisplays complex regulation of natural genetic competence. Competence development inS. mutansis controlled by a peptide derived from ComS (XIP); which along with the cytosolic regulator ComR controls the expression of the alternative sigma factorcomX, the master regulator of competence development. Recently, a gene embedded within the coding region ofcomXwas discovered and designatedxrpA(comXregulatorypeptideA). XrpA was found to be an antagonist of ComX, but the mechanism was not established. In this study, we reveal through both genomic and proteomic techniques that XrpA is the first describe negative regulator of ComRS systems in streptococci. Transcriptomic and promoter activity assays in the ΔxrpAstrain revealed an up-regulation of genes controlled by both the ComR- and ComX-regulons. Anin vivoprotein crosslinking andin vitrofluorescent polarization assays confirmed that the N-terminal region of XrpA were found to be sufficient in inhibiting ComR-XIP complex binding to ECom-box located within thecomXpromoter. This inhibitory activity was sufficient for decreases in PcomXactivity, transformability and ComX accumulation. XrpA serving as a modulator of ComRS activity ultimately results in changes to subpopulation behaviors and cell fate during competence activation.ABBREVIATED SUMMARYStreptococcus mutansdisplays complex regulation of natural genetic competence, highlighted by a novel gene,xrpA, embedded within the coding region for the master regulator ComX. We show that XrpA modulates ComRS-dependent activation ofcomXexpression, resulting in changes to sub-population behaviors, including cell lysis. XrpA is the first described inhibitor of a ComRS system and, because it is unique toS. mutansit may be targetable to prevent diseases caused by this pathogen.
Convergence in form and function overcomes non-parallel evolutionary histories in a Holarctic fish
Authors: Jacobs Arne , Carruthers Madeleine , Yurchenko Andrey , Gordeeva Natalia V. , Alekseyev Sergei S. , Hooker Oliver , Leong Jong S. , Minkley David R. , Rondeau Eric B. , Koop Ben F. , Adams Colin E. , Elmer Kathryn R. 
Published: February 2018

AbstractUnderstanding the extent to which evolution is predictable under multifarious selection is a longstanding question in evolutionary biology. However, the interplay of stochastic and contingent factors influencing the extent of parallelism in nature is not well understood. To test the predictability of evolution, we studied a ‘natural experiment’ on different organismal levels across lakes and evolutionary lineages of a freshwater salmonid fish, Arctic charr (Salvelinus alpinus). We identified significant phenotypic parallelism between Arctic charr ecotype pairs within a continuum of parallel evolution and highly parallel adaptive morphological traits. Variability in phenotypic predictability was explained by complex demographic histories, differing genomic backgrounds and genomic responses to selection, variable genetic associations with ecotype, and environmental variation. Remarkably, gene expression was highly similar across ecotype replicates, and explained the observed parallelism continuum. Our findings suggest that parallel evolution by non-parallel evolutionary routes is possible when the regulatory molecular phenotype compensates for divergent histories.
Integrative proteomics and bioinformatic prediction enable a high-confidence apicoplast proteome in malaria parasites
Authors: Boucher Michael J. , Ghosh Sreejoyee , Zhang Lichao , Lal Avantika , Jang Se Won , Ju An , Zhang Shuying , Wang Xinzi , Ralph Stuart A. , Zou James , Elias Joshua E. , Yeh Ellen 
Published: February 2018

AbstractMalaria parasites (Plasmodium spp.) and related apicomplexan pathogens contain a non-photosynthetic plastid called the apicoplast. Derived from an unusual secondary eukaryote-eukaryote endosymbiosis, the apicoplast is a fascinating organelle whose function and biogenesis rely on a complex amalgamation of bacterial and algal pathways. Because these pathways are distinct from the human host, the apicoplast is an excellent source of novel antimalarial targets. Despite its biomedical importance and evolutionary significance, the absence of a reliable apicoplast proteome has limited most studies to the handful of pathways identified by homology to bacteria or primary chloroplasts, precluding our ability to study the most novel apicoplast pathways. Here we combine proximity biotinylation-based proteomics (BioID) and a new machine learning algorithm to generate a high-confidence apicoplast proteome consisting of 346 proteins. Critically, the high accuracy of this proteome significantly outperforms previous prediction-based methods and extends beyond other BioID studies of unique parasite compartments. Half of identified proteins have unknown function, and 77% are predicted to be important for normal blood-stage growth. We validate the apicoplast localization of a subset of novel proteins and show that an ATP-binding cassette protein ABCF1 is essential for blood-stage survival and plays a previously unknown role in apicoplast biogenesis. These findings indicate critical organellar functions for newly discovered apicoplast proteins. The apicoplast proteome will be an important resource for elucidating unique pathways derived from secondary endosymbiosis and prioritizing antimalarial drug targets.
Salary or job interest? How salary and job interest moderates the willingness to apply for a job
Authors: Chi Hsingkuang , Yeh Hueryren , Guo Tingwei 
Published: February 2018

Purpose
The purpose of this paper is to explore whether salary and job interest moderates the relationship between corporate image and willingness to apply for a job and to examine that salary or job interest has a stronger influence on willingness to apply for a job.

Design/methodology/approach
Research data were obtained through questionnaires by the method of convenience sampling, distributed in employment expos and career guidance centers in Taichung and Chiayi area, Taiwan. In total, 300 questionnaires were collected. Excluding the invalid questionnaires, there were 285 valid questionnaires. Then, the study applied hierarchical regressions to test moderating effects and each hypothesis.

Findings
The study found that corporate image, salary, and job interest have significant positive effects on willingness to apply. In order of level of influence on willingness to apply, the factors successively are job interest, salary, and corporate image. Both salary and job interest will exert moderating effects on willingness to apply, and job interest has a stronger influence than salary.

Research limitations/implications
This study was limited on sample selection from only two regions, in addition to time and space restrictions. However, the research results still help an employer to understand the priority factors that may influence a job seeker’s decision to apply for a job.

Originality/value
A company with a good corporate image and generous salary system can enhance the interest of job seekers. At the same time, if the job content is consistent with the interest of the job seekers, they will be more eager to apply. It would be beneficial for both enterprises and applicants when the right candidate in the sea of job seekers is chosen for the right job.
Tit for tat: burnout as a mediator between workplace incivility and instigated workplace incivility
Authors: Loh Jennifer M.I. , Loi Natasha 
Published: February 2018

Purpose
The purpose of this paper is to investigate the role of burnout as a mediator in the relationship between workplace incivility (WI) and instigated WI.

Design/methodology/approach
A survey of 303 white collar employees from small- to medium-size industries in Australia was conducted. Self-reported measures were used to obtain data on WI, burnout, and instigated WI. Mediation analyses with bootstrap via PROCESS was used ascertain the proposed relationship.

Findings
Results indicated that WI was positively linked to instigated WI. Importantly, results indicated that burnout fully mediated the relationship between WI and instigated WI.

Research limitations/implications
The correlational and self-report nature of the study exclude inference about causality between variables and may be more prone to bias. However, despite these limitations, pre- and post-cautionary steps were taken to ensure that these biases were kept at bay as much as is possible.

Practical implications
The study highlights that burnout may be an important underlying mechanism responsible for target’s and perpetrator’s uncivil relationships toward each other. Management should be cognizant of possible burnout among employees who experienced WI and to take appropriate training as preventive measures for WI.

Originality/value
This study responded to the call for more empirical investigation of WI. This study also integrated conservation of resources and the spiral of incivility theories to develop a theoretical model which linked WI to instigated WI.
A new coupled ARMA-FGM model and its application in the internet third-party payment forecasting in China
Authors: Mao Shuhua , Wang Xianpeng , Zhu Min 
Published: February 2018

PurposeWith the rapid development of e-commerce in China, the third-party payment system greatly improved the efficiency and volume of the entire trading market. The purpose of this paper is to put forward a suitable prediction model to analyse its development trend.Design/methodology/approachThe authors analyse internet third-party payments in China, taking into account online payment transaction values coupled with an ARMA model and the fractional grey model (FGM). First, the rolling FGM model is applied in order to characterise the trends of the transaction volume. The influence of the initial value change on the FGM model is analysed. The optimisation mean absolute percentage error (MAPE) model is constructed to determine the optimal translational values, the corresponding optimal accumulation order and optimal inverse accumulation order.FindingsThis paper uses China’s recent third-party online payment data to quantify its development trend. The authors find the coupling model suitable for the development trend of third-party online payment transaction. The results show that the model is suitable to quantify its development trend of China’s recent third-party online payment.Originality/valueConsidering the complex influence factors that lead to the third-party online payment volume data of time-varying grey feature, this paper combines the FGM with ARMA model to describe the development of third-party payment mode.
Sleepwear with lateralized thermal properties for the treatment of sleep disturbance in women
Authors: Glovinsky Paul , Zavrel Erik 
Published: February 2018

Purpose
The authors’ innovation is specially constructed sleepwear – which the authors have dubbed “Janus Sleepwear” – for the treatment of sleep disturbance caused by thermal dysregulation, a problem most often seen in women. The authors have designed and tested a simple and comfortable garment with lateralized thermal properties that promotes either thermal conduction or thermal insulation depending upon body position. This innovation will allow sleepers to auto-regulate proximal skin temperature through subtle movements during brief transient arousals, preserving overall sleep architecture. The paper aims to discuss this issue.

Design/methodology/approach
The authors have constructed several prototypes of sleepwear with lateralized thermal properties and conducted small-scale piloting of the garment. Volunteers wore the special sleepwear while awake and performed a series of controlled body position changes. Temperature at several proximal anatomical sites was monitored using temperature sensors known as iButtons.

Findings
Janus Sleepwear can facilitate more rapid cooling, compared to control sleepwear, when the conductive side faces the ambient environment and can maintain temperature with less loss of heat when the insulating side faces the ambient environment.

Originality/value
Thermoregulation plays a key role in promoting and maintaining sleep. Thermal dysregulation and sleep disturbance most commonly occur in women. Sensitivity to ambient temperature stressors suggests it may prove beneficial for such women to maintain as narrow a temperature range as possible during sleep. A person wearing Janus Sleepwear will be able to effectively “steer” her body in response to subjective and subconscious perceptions of thermal discomfort to maintain optimal conditions while asleep.
What price a welcome? Understanding structure agency in the delivery of respectful midwifery care in Uganda
Authors: Ackers Louise , Webster Hannah , Mugahi Richard , Namiiro Rachel 
Published: February 2018

Purpose
The purpose of this paper is to present the findings of research on mothers and midwives’ understanding of the concept of respectful care in the Ugandan public health settings. It focusses on one aspect of respect; namely communication that is perhaps least resource-dependent. The research found endemic levels of disrespect and tries to understand the reasons behind these organisational cultures and the role that governance could play in improving respect.

Design/methodology/approach
The study involved a combination of in-depth qualitative interviews with mothers and midwives together with focus groups with a cohort of midwives registered for a degree.

Findings
The findings highlight an alarming level of verbal abuse and poor communication that both deter women from attending public health facilities and, when they have to attend, reduces their willingness to disclose information about their health status. Respect is a major factor reducing the engagement of those women unable to afford private care, with health facilities in Uganda.

Research limitations/implications
Access to quality care provided by skilled birth attendants (midwives) is known to be the major factor preventing improvements in maternal mortality and morbidity in low income settings. Although communication lies at the agency end of the structure-agency continuum, important aspects of governance contribute to high levels of disrespect.

Originality/value
Whilst there is a lot of research on the concept of respectful care in high income settings applying this to the care environment in low resource settings is highly problematic. The findings presented here generate a more contextualised analysis generating important new insights which we hope will improve the quality of care in Uganda health facilities.
The trickle-down effect of psycho-social constructs and knowledge deficiencies as organizational barriers to cost performance on highway projects
Authors: Amadi Alolote Ibim , Higham Anthony 
Published: February 2018

Purpose
This study aims to proffer a theoretical narrative explaining the poor financial performance of public highway agencies in Nigeria. This study critically spotlights seminal works in the literature offering theoretical narratives on the poor financial performance of public infrastructure projects, to discuss whether they adequately capture the relationship between psychological factors, project governance/leadership issues and knowledge/skill deficiencies related to the cost performance of infrastructure projects in the developing world. The evaluation reveals the predominant contextual exclusivity of these theoretical narratives to the developed world, which tend to under-represent developing countries, such as those on the African continent.

Design/methodology/approach
Using a case study research strategy, longitudinal documentary/archival data for 61 highway projects were analyzed. In total, 16 interviews were also conducted with highway officials from the three highway agencies responsible for the execution of the projects. A two-stage deductive-inductive thematic analysis of the collated data was carried out to identify barriers to the financial management of public highway projects, the result of which is cognitively mapped out.

Findings
The study showcases empirical insight on cost overruns experienced in Nigerian public projects, because of the trickle-down effect of human and organizational environment, as well as because of workers’ knowledge/skill deficiencies.

Research limitations/implications
The developed theory is contextual to Nigeria, and there is scope for testing its generalisability to other developing nations.

Originality/value
The in-depth trajectory provided uncovers an intricate web of technical and psycho-social, organizational and institutional issues, which have not been identified and explained by previous theoretical narratives.
Coping behaviors to deal with stress and stressor consequences among construction professionals
Authors: Enshassi Adnan , Al-Swaity Eman , Abdul Aziz Abdul Rashid , Choudhry Rafiq 
Published: February 2018

Purpose
Construction experts face several types of stresses at construction sites. The purpose of this study is to recognize and investigate dominant coping behaviors to overcome stress among construction professionals at the Gaza Strip.

Design/methodology/approach
For the purpose of this paper, a survey which used self-administrative questionnaires was conducted. A total of 320 questionnaires were distributed randomly to construction professionals working at the Gaza Strip. From the total questionnaires that were distributed, 183 were returned. This shows a 51 per cent response rate. Relative importance index and principal component analysis were applied to examine the responses. This study explored two central coping behaviors, namely, problem-focused and emotion-focused behaviors.

Findings
In relation to the problem-focused behaviors, a factor analysis revealed three underlying factors, namely, planned and constructive review problem-solving, need for social contributory support and confronted coping mechanism. As for emotion-focused coping behavior strategy, three principal factors were identified and named in order of their significance. These three principal factors include accepting responsibility, avoidance and seeking emotional support.

Originality/value
There is limited attention from researchers with regard to coping behaviors so as to deal with stress and stressors in the Palestinian construction industry. Therefore, this study aims to fill the gap for stress-related issues in the construction sector of Palestine. The outcomes of this study will be valuable for construction companies which pursue improvements in human resources, productivity and future strategy.