bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of Perfectionism in Junior Athletes: A Three-Sample Study of Coach and Parental Pressure
Authors: Madigan Daniel J. , Curran Thomas , Stoeber Joachim , Hill Andrew P. , Smith Martin M. , Passfield Louis 
Published: June 2019

Perfectionism predicts cognitions, emotions, and behaviors in sport. Nonetheless, our understanding of the factors that influence its development is limited. The authors sought to address this issue by examining the role of coach and parental pressure in the development of perfectionism in sport. Using 3 samples of junior athletes (16–19 years; cross-sectionaln = 212, 3-month longitudinaln = 101, and 6-month longitudinaln = 110), the authors examined relations between coach pressure to be perfect, parental pressure to be perfect, perfectionistic strivings, and perfectionistic concerns. Mini meta-analysis of the combined cross-sectional data (N = 423) showed that both coach pressure and parental pressure were positively correlated with perfectionistic strivings and perfectionistic concerns. In contrast, longitudinal analyses showed that only coach pressure predicted increased perfectionistic strivings and perfectionistic concerns over time. Overall, our findings provide preliminary evidence that coaches may play a more important role in the development of junior athletes’ perfectionism than parents.
Respiration and Small Colony Variants of
Staphylococcus aureus
Authors: Proctor Richard 
Published: June 2019

ABSTRACT

Respiratory mutants, both naturally occurring and genetically constructed, have taught us about the importance of metabolism in influencing virulence factor production, persistence, and antibiotic resistance. As we learn more about small colony variants, we find that
Staphylococcus aureus
has many pathways to produce small colony variants, although the respiratory variants are the best described clinically and in the laboratory.
2 The incidence of undiagnosed coeliac disease in patients presenting with stress fracture to a tertiary referral centre
Authors: Smith R , Baldock J , FitzPatrick M , Jones N , Newton J 
Published: June 2019

AimStress fracture aetiology is often multifactorial and laboratory blood tests (LBT) can unmask underlying metabolic bone risk factors and disorders. Coeliac disease (CD) is associated with low bone mineral density and an increased risk of fractures.1In addition, there are rare reports of occult CD presenting with stress fractures.2Anti-tissue transglutaminase antibody (TTG) testing has a high sensitivity and specificity for CD and is used as a screening test.3This report examines the incidence of undiagnosed CD in patients presenting with stress fractures to a Sport and Exercise Medicine (SEM) clinic.MethodsA retrospective analysis of 100 consecutive patients with radiologically proven stress fractures presenting to a single tertiary NHS SEM clinic was performed. Age, gender, fracture site, co-morbidities, TTG result and subsequent investigations were examined. Records were reviewed to confirm LBT, including TTG, had been performed at the time of diagnosis.ResultsSeventy patients (70%) were female and mean age was 37 years (range 18–69). Metatarsal (35%) and tibial (21%) fractures were most common. TTG was performed in 85 patients. Two patients were excluded due to pre-existing CD. Five patients (5/83 (6%), mean age 38 years (28–57), 80% female) had a positive TTG; three of whom had CD confirmed by endoscopic biopsy and two are awaiting investigation. Four patients with a positive TTG underwent dual energy X-ray absorptiometry, with osteopenia (T-Score between −1.0 and −2.5) found in 75% of cases, although only one had a Z-score less than -2.0.ConclusionIn this cohort, the incidence of undiagnosed CD was between 3.6% to 6%, with a prevalence between 5% to 7%, approximately 5-fold higher than UK population estimates. We recommend that TTG screening should be performed in all patients presenting with stress fractures to identify underlying CD. Further work is required to confirm this association and elucidate potential underlying mechanisms.ReferencesHeikkilä K, Pearce J, Mäki M, et al. Celiac disease and bone fractures: a systematic review and meta-analysis.J Clin Endocrinol Metab2015;100(1):25–34.Gilbody J, Trevett M. Coeliac disease presenting with bilateral fibular stress fractures.Foot Ankle Surg2009;15:96–100.3. Downey L, Houten R, Murch S, Longson D, Group GD. Recognition, assessment, and management of coeliac disease: summary of updated NICE guidance.BMJ2015;351:h4513.
3 Platelet rich plasma for acute achilles tendon rupture: a double-blind, multicentre, randomised, placebo-controlled trial
Authors: Keene DJ , Alsousou J , Harrison P , Hulley P , Wagland S , Schlüssel MM , Dutton S , Lamb SE , Willett K 
Published: June 2019

AimSlow recovery and disability after Achilles tendon rupture are major challenges. Platelet Rich Plasma (PRP) is an autologous supraphysiological concentration of platelets from whole blood that has demonstrated positive cellular and physiological effects on healing in the laboratory and is widely used in musculoskeletal treatments. However, evidence from adequately powered, robust clinical trials is lacking. We aimed to determine the clinical efficacy of PRP for treatment of acute Achilles tendon rupture.Methods230 adults starting Achilles rupture non-surgical management within 12 days of injury were randomised to PRP injection or dry needle insertion to the rupture gap, under local anaesthetic. Participants were blinded to study treatment and received standardised rehabilitation. Blinded outcome assessments were at 4, 7, 13, and 24 weeks. The primary outcome was muscle-tendon function assessed by work performed during the heel-rise endurance test (HRET), measured with the Limb Symmetry Index (LSI) (0–100%; 100% denotes full recovery) at 24 weeks. Secondary outcomes were the Achilles Tendon Rupture Score (ATRS), quality of life (SF-12), pain and goal attainment. The trial was prospectively registered.ResultsOf 230 participants, 114 were allocated to PRP injection (103 received PRP), 116 were allocated to and received placebo. At 24 weeks, 201/230 (87%) completed the HRET and 214/230 (93%) completed patient reported outcomes. Participant characteristics between the groups were similar. There was no difference between groups at 24 weeks in LSI (mean difference = -4.373; 95% CI −11.217 to 2.471; p=0.195). There were no differences in the secondary outcomes and adverse event rates.ConclusionThis trial design and standardised PRP preparation secure the first robust clinical trial evidence for PRP in managing Achilles tendon rupture, and suggest that PRP offers no patient benefit. The use of PRP in soft tissue injuries must be questionable unless supported by equally robust evidence indicating positive outcomes.
5 The motivators and barriers to physical activity in primary prevention of chronic disease
Authors: Pavitt A 
Published: June 2019

BackgroundRegular physical activity is protective against many chronic diseases. Despite this, 39% of adults in the UK are insufficiently active with an increased risk of chronic disease. Moving Medicine is an online resource developed by the FSEM to facilitate clinician-led conversations to reduce the risk of chronic disease through increased physical activity.AimThis is the first review to categorise and understand the principle motivators for and barriers against physical activity, for the primary prevention of chronic disease. It has informed the development of a national Moving Medicine resource.MethodsA structured search of MEDLINE and OpenGrey, augmented by handsearching of reference lists and contents of key journals. Qualitative evidence was then synthesised thematically.ResultsThirteen papers were selected as being of good quality (structured interviews and focus groups rather than questionnaires) and relevant to the aims of this review. Motivators identified were grouped into: anticipated positive effects, support/encouragement, social aspects, environmental aspects, goal-setting, and the use of feedback. Barriers to physical activity were grouped into: time constraints, physical health problems, environmental aspects, cost and poor communication.Building results into the resourceThe results of this review were presented to an expert panel of SEM doctors, GPs, nurses, physiotherapists, and patients. This multidisciplinary team then helped shape the primary prevention resource on the Moving Medicine website. See examples from the resource below.ConclusionGood quality conversations on physical activity in healthcare require an understanding of the key motivators and barriers reported by patients. Combining this qualitative review with the knowledge, skills and the experience of a multidisciplinary expert panel has enabled the development of a unique patient-centred primary prevention resource. Delivering this information through MovingMedicine.ac.uk is a vital step in using these important findings to inform routine clinical practice across the NHS. This should facilitate an increase in the proportion of adults meeting recommended physical activity levels and therefore reduce the rates of chronic disease.
Patient perceptions and interactions with their web portal-based laboratory results
Authors: Robinson Sean , Reed Melissa , Quevillon Travis , Hirvi Ed 
Published: June 2019

BackgroundThe movement to improve patient-centred care, combined with the development of user-friendly technology has led to the spread of electronic patient portals (EPP). Little research has examined the effects of providing patients with access to their laboratory results on their healthcare and health behaviours.ObjectiveThe purpose of this study was to gain insight into the use of EPPs, understand why patients use EPPs to access their laboratory results and explore its impact on their health.MethodSemistructured interviews were conducted with 21 patients who used the laboratory results section of an EPP. Interviews were analysed using a grounded theory approach.ResultsParticipant interactions with their laboratory results varied based on their level of understanding of their results. Benefits of EPP-based access to test results included convenience, fewer appointments and decreased anxiety. Some participants described increased engagement in their healthcare and positive health changes. However, some were concerned about receiving alarming test results.ConclusionHealthcare providers using EPPs to provide patients with their test results should try to ensure their patients understand their test results. Patient comprehension of test results may be improved by having providers comment on the meaning of test results and by encouraging patients to use specific websites and search options within EPPs.
Trend of intestinal infectious diseases recorded at a tertiary care hospital in India: an ICD-10 analysis
Authors: Jathanna P N Roopalekha , Vijeta Ramya , Jathanna Vinod R 
Published: June 2019

The World Health Organization identifies the leading cause of morbidity and mortality in developing countries as infectious and communicable diseases. Health records coded uniformly using ICD-10 can form an accurate database and conclusions drawn from this are extremely important for understanding the public health situation.The aim of this study is to analyse the trend of intestinal infectious diseases recorded at a tertiary care hospital in India.A retrospective disease index study was conducted on data comprising 5317 cases from 2012 to 2016 for intestinal infectious diseases, analysed with ICD-10.Of these, 5.5% were from the age group 0-5 years; 57.66% were male; and 85% deaths in this cohort (62/73) were due to diarrhoea and gastroenteritis of presumed infectious origin.The findings of this study highlight an urgent need for health education among the population regarding infectious intestinal diseases and to redesign health promotion and preventive strategies for addressing these problems.
“You can smell the freedom”: a qualitative study on perceptions and experiences of sex among Swedish men who have sex with men in Berlin
Authors: Dennermalm Nicklas , Ingemarsdotter Persson Kristina , Thomsen Sarah , Forsberg Birger C 
Published: June 2019

PurposeThe purpose of this study was to explore the perceptions and experiences of sex among Swedish Men who have Sex with Men (MSM) in Berlin.BackgroundMSM are disproportionally affected by HIV.Berlin is also a key destination when looking into where Swedish MSM sero-convert, while travelling.MethodA qualitative study with semi-structured interviews using open-ended questions with participants recruited through network sampling. Data were analysed with content analysis.Participants15 Swedish cis-men (as in non-transgender) who have sex with men aged 25–44 years, who travelled to or were living in Berlin. To be included in the study, the participants had to be cis-MSM, Swedish citizens, spending time in Berlin and having sex in both settings.ResultsFor a majority of the participants, sex was the main reason for going to Berlin but cultural aspects like art and the techno scene were also important. Berlin was perceived as a sex-oriented city providing venues where respondents did not have to care about reputation and status and where social and sexual spaces co-existed side by side. This in sharp contrast to Sweden, which represented a limiting environment both in culture and what was available culturally and sexually.ConclusionThe men interviewed experienced multiple partners and had a broad sexual repertoire both abroad and at home. However, the behaviour was amplified in Berlin. The men did not alter their safer sex practice depending on if they had sex in Sweden or Berlin. The high mobility and vulnerability for HIV/sexually transmitted infection (STI) among these men highlights the need of increased access to antiretroviral treatment, pre-exposure prophylaxis for HIV and low-threshold HIV/STI testing services in Europe.
Development of a core outcome set for traumatic brachial plexus injuries (COMBINE): study protocol
Authors: Miller Caroline , Cross Jane , Power Dominic M , Kyte Derek , Jerosch-Herold Christina 
Published: June 2019

IntroductionTraumatic brachial plexus injury (TBPI) involves major trauma to the large nerves of the arm which control the movement and sensation. Fifty per cent of injuries result in complete paralysis of the arm with many other individuals having little movement, sensation loss and unremitting pain. The injury often causes severe and permanent disability affecting work and social life, with an estimated cost to the National Health Service and the economy of £35 million per annum. Advances in microsurgery have resulted in an increase in interventions aimed at reconstructing these injuries. However, data to guide evidence-based decisions is lacking. Different outcomes are used across studies to assess the effectiveness of treatments. This has impeded our ability to synthesise results to determine which treatments work best. Studies frequently report short-term clinical outcomes but rarely report longer term outcomes and those focused on quality of life. This project aims to produce a core outcome set (COS) for surgical and conservative management of TBPI. The TBPI COS will contain a minimum set of outcomes to be reported and measured in effectiveness studies and collected through routine clinical care.Methods and analysisThis mixed-methods project will be conducted in two phases. In phase 1 a long list of patient-reported and clinical outcomes will be identified through a systematic review. Interviews will then explore outcomes important to patients. In phase 2, the outcomes identified across the systematic review, and the interviews will be included in a three-round online Delphi exercise aiming to reach consensus on the COS. The Delphi process will include patient and healthcare participants. A consensus meeting will be held to achieve the final COS.Ethics and disseminationThe use of a COS in TBPI will increase the relevance of research and clinical care to all stakeholders, facilitate evidence synthesis and evidence-based decision making. The study has ethical approval.Trial registration numbersCRD42018109843.
Screening for and management of comorbidities after a nurse-led program: results of a 3-year longitudinal study in 769 established rheumatoid arthritis patients
Authors: Gossec Laure , Soubrier Martin , Foissac Frantz , Molto Anna , Richette Pascal , Beauvais Catherine , Ruyssen-Witrand Adeline , Perdriger Aleth , Chary-Valckenaere Isabelle , Mouterde Gael , Dernis Emanuelle , Euller-Ziegler Liana , Flipo René-Marc , Gilson Mélanie , Guis Sandrine , Mariette Xavier , Pouplin Sophie , Marhadour Thierry , Schaeverbeke Thierry , Sordet Christelle , Fayet Françoise , Dougados Maxime 
Published: June 2019

Background/purposeCardiovascular (CV) risk, cancer, infections and osteoporosis should be screened for in rheumatoid arthritis (RA). The objective was to assess 3-year effects of a nurse visit for comorbidity counselling.MethodsThis was an open long-term (3 years) extension of the Comorbidities and Education in Rheumatoid Arthritis 6-month randomised controlled trial in which patients with definite, stable RA were visiting a nurse for comorbidity counselling. Comorbidity status was assessed and nurses provided advice on screening and management, at baseline and 3 years later. A score was developed to quantify comorbidity screening and management: 0–100, where lower scores indicate better screening and management. The score was compared between baseline and 3-year assessment using a Wilcoxon test for paired data.ResultsOf the 970 recruited patients, 776 (80%) were followed-up at 2–4 years and 769 (79%) had available data for comorbidities at both time points: mean (±SD) age 58 (±11) years and mean disease duration 14 (±10) years; 614 (80%) were women, the mean Disease Activity Score 28 was 3.0±1.3, and 538 (70%) were receiving a biologic. At baseline, the mean comorbidity screening score was 36.6 (±19.9) and it improved at 3 years to 24.3 (±17.8) (p<0.0001), thus with a relative improvement of 33% (improvement of 12 points). CV risk screening, vaccination status and bone densitometry performance improved the most.ConclusionsComorbidity screening was suboptimal but improved notably over 3 years, after a nurse-led programme aiming at checking systematically for comorbidity screening and giving patient advice. This long-term efficacy pleads in favour of nurse-led interventions to better address comorbidities in RA.Trial registration numberNCT01315652
Computing from projections of random points
Authors: Greenberg Noam , Miller Joseph S. , Nies André 
Published: June 2019

We study the sets that are computable from both halves of some (Martin–Löf) random sequence, which we call [Formula: see text]-bases. We show that the collection of such sets forms an ideal in the Turing degrees that is generated by its c.e. elements. It is a proper subideal of the [Formula: see text]-trivial sets. We characterize [Formula: see text]-bases as the sets computable from both halves of Chaitin’s [Formula: see text], and as the sets that obey the cost function [Formula: see text]. Generalizing these results yields a dense hierarchy of subideals in the [Formula: see text]-trivial degrees: For [Formula: see text], let [Formula: see text] be the collection of sets that are below any [Formula: see text] out of [Formula: see text] columns of some random sequence. As before, this is an ideal generated by its c.e. elements and the random sequence in the definition can always be taken to be [Formula: see text]. Furthermore, the corresponding cost function characterization reveals that [Formula: see text] is independent of the particular representation of the rational [Formula: see text], and that [Formula: see text] is properly contained in [Formula: see text] for rational numbers [Formula: see text]. These results are proved using a generalization of the Loomis–Whitney inequality, which bounds the measure of an open set in terms of the measures of its projections. The generality allows us to analyze arbitrary families of orthogonal projections. As it turns out, these do not give us new subideals of the [Formula: see text]-trivial sets; we can calculate from the family which [Formula: see text] it characterizes. We finish by studying the union of [Formula: see text] for [Formula: see text]; we prove that this ideal consists of the sets that are robustly computable from some random sequence. This class was previously studied by Hirschfeldt [D. R. Hirschfeldt, C. G. Jockusch, R. Kuyper and P. E. Schupp, Coarse reducibility and algorithmic randomness, J. Symbolic Logic 81(3) (2016) 1028–1046], who showed that it is a proper subclass of the [Formula: see text]-trivial sets. We prove that all such sets are robustly computable from [Formula: see text], and that they form a proper subideal of the sets computable from every (weakly) LR-hard random sequence. We also show that the ideal cannot be characterized by a cost function, giving the first such example of a [Formula: see text] subideal of the [Formula: see text]-trivial sets.
Description of chalk microporosity via automated mathematical morphology on scanning electron microphotographs
Authors: Meyer Aurelien G. , Nourani Meysam , Stemmerik Lars 
Published: June 2019

The spatial geometry of microporosity influences fluid flow through chalk reservoirs and aquifers, and, hence, numerous geological processes. Analysing porosity is thus often critical in geological studies. Techniques such as mercury injection capillary pressure (MICP), nuclear magnetic resonance (NMR) and X-ray computed tomography (CT) are expensive, and hence often inapplicable to many geological studies, which often necessitate the analysis of large numbers (hundreds) of samples.
However, scanning electron microscopes (SEM) have become widely available, and SEM imagery analysis, therefore, is cheaper and faster. However, extracting meaningful porosity descriptors from SEM images can be difficult, in part because of the difficulty in digitally separating pores in laterally continuous pore networks. Moreover, mathematical morphology can be automated to collect porosity parameters from hundreds of images in a short time frame. The technique also quantifies the shape complexity of porosity. Considering the influence of pore geometry on fluid flow, the capacity of image analysis to deconstruct the pore network by pore shapes is crucial when building flow models. This study concludes that mathematical morphology constitutes an alternative to other techniques in geological studies of microporosity. Lithologies dominated by micro- and nanoporosity, such as shales and tight sandstones, could also benefit from this technique.