bluuebunny/crossref_metadata_2025_split huggingface dataset:
DESENVOLVIMENTO INICIAL DO MILHO EM RESPOSTA A DOSES DE POTÁSSIO
Authors: GOMES MATEUS DE PAULA , CORDIDO JOÃO PEDRO DE BARROS REICAO , SANTOS MÁRCIO LUIZ DOS , PEREIRA ARIANA MOTA 
Published: May 2018

RESUMO - Objetivou-se avaliar o efeito de doses de potássio e níveis de compactação de solos no desenvolvimento inicial e na absorção de cátions em plantas de milho. Foram desenvolvidos dois experimentos utilizando amostras de um Latossolo Vermelho de textura média (LV) e de um Latossolo Vermelho-Amarelo de textura muito argilosa (LVA). Os ensaios foram conduzidos em blocos casualizados com arranjo fatorial 3×6, sendo três densidades de solo e seis doses de potássio, com três repetições. A compactação do solo não influenciou no acúmulo de matéria seca nem na absorção dos cátions pelas plantas de milho. O aumento das doses de K reduziu a absorção e o teor de Ca das plântulas de milho cultivadas no LVA e reduziu a absorção e teor de Mg das plântulas de milho cultivadas em ambos os solos. O aumento das doses de K favoreceu a absorção de Mn, Fe, Cu e Na em plântulas de milho cultivadas em LV. As doses de K não influenciaram na absorção de Ca e Zn em plântulas de milho cultivadas em LV, nem na absorção de Fe, Zn, Cu, Mn, Na em plântulas de milho cultivadas em LVA. Palavras-chave: inibição da absorção, Zea mays, absorção de cátions. INITIAL MAIZE DEVELOPMENT IN RESPONSE TO POTASSIUM DOSES ABSTRACT - The objective of this work was to evaluate the effect of potassium doses and levels of soil compaction on initial development and cation uptake in maize plants. Two experiments were carried out using samples of a Red Latosol (LV) and a Red-Yellow Latosol with very clayey texture (LVA). The trials were conducted in randomized blocks with factorial arrangement 3×6, being three soil densities and six potassium doses, with three replications. Soil compaction did not influence the accumulation of dry matter or cation uptake in maize plants. Increased K doses reduced the uptake and Ca content in maize plants grown in the LVA and reduced the uptake and Mg content in maize plants grown in both soils. Increased K doses favored the absorption of Mn, Fe, Cu and Na in maize seedlings when grown in LV. K doses did not influence the uptake of Ca and Zn in maize seedlings grown in LV, nor the absorption of Fe, Zn, Cu, Mn and Na in maize seedlings grown on LVA. Keywords: inhibition of absorption, Zea mays, cation absorption.
RESPOSTA DO MILHO SAFRINHA À ADUBAÇÃO EM DUAS ÉPOCAS DE SEMEADURA
Authors: SIMAO EDUARDO DE PAULA , RESENDE ÁLVARO VILELA , GONTIJO NETO MIGUEL MARQUES , BORGHI EMERSON , VANIN ÀLISSON 
Published: May 2018

RESUMO - Neste trabalho, objetivou-se avaliar a resposta do milho à adubação NPK, em semeadura realizada nos meses de janeiro e fevereiro, sucedendo a cultura da soja, em Rio Verde-GO. O experimento foi conduzido em delineamento de blocos casualizados, num esquema fatorial 4x2, constituído por quatro opções de adubação NPK na semeadura, com ou sem adubação nitrogenada de cobertura. Foram cultivados os híbridos P 30F53 YH e DKB 310 PRO, no primeiro e segundo anos, respectivamente, e coletados os dados de altura de plantas e de espigas, número de espigas, de fileiras por espiga, de grãos por fileira, massa de 1.000 grãos e produtividade. A produtividade de grãos do milho safrinha é influenciada pelas épocas de semeadura que definem as condições de disponibilidade hídrica, e pela adubação nitrogenada em cobertura, sem expressar resposta à adubação NPK na semeadura, que, em janeiro, favorece a produtividade, por conciliar melhor a distribuição de chuvas no final da fase de desenvolvimento vegetativo e na fase reprodutiva, etapas críticas para o potencial produtivo do milho. Independentemente da época de cultivo e da adubação NPK na semeadura, a aplicação de N em cobertura promove ganho significativo de produtividade da cultura. Palavras-chave: sucessão de culturas, adubação de manutenção, veranico, Zea mays L. SECOND-SEASON CORN RESPONSE TO FERTILIZATION IN TWO SEEDING TIMES ABSTRACT - This study aimed to evaluate the response of maize to NPK fertilization in sowing in January and February, succeeding soybean crop, in Rio Verde, State of Goiás, Brazil. The experiment was conducted in a randomized block design in a 4x2 factorial scheme, and it consisted of four NPK options in seeding time, with or without nitrogen topdressing. Hybrids P 30F53 YH and DKB 310 PRO were grown in the first and second year, respectively. We collected the data of plant height, ears height, number of ears, number of rows per ear, number of grains by row, thousand kernel weight and productivity. The productivity of second-season maize grain is influenced by sowing time, which defines the conditions of water availability, and the nitrogen fertilization, without expressing response to NPK fertilizer at sowing. Seeding in January favors productivity to reconcile better distribution of rainfall at the end of the vegetative growth phase and reproductive phase, critical steps for the production of maize potential. Regardless of the growing season and NPK fertilization at sowing, application of N topdressing promotes significant productivity gain.Keywords: crop succession, fertilization, nutrient requirements, dry spell, Zea mays L.
Hubungan Pengetahuan Kesehatan Gigi dan Mulut dengan Karies Gigi pada Mahasiswa Baru Fakultas Kedokteran Gigi Universitas Jember Tahun Akademik 2016/2017 (Correlation of Oral Health Knowledge with Dental Caries in First Grade Dentistry Students of Jember
Authors: Rahtyanti Galuh Cita Sari , Hadnyanawati Hestieyonini , Wulandari Erawati 
Published: May 2018

Background: One of major oral health problem found in oral cavity is dental caries. Several factors can induce dental caries such as economical factors, excessive high sugar content foods consumption, and neglect of oral hygiene due to lack of knowledge in how important is teeth and mouth maintenance. Objective: To analyzed correlation between oral health knowledge and dental caries in first grade Dentistry students of Jember University Academic Year 2016/2017. This research used cross sectional approach with total respondents of 119 students. The assessment of oral health knowledge was done by questionnaire and DMF-T index was used to evaluated dental caries in oral cavity. Results and Conclusion: The majority of oral health knowledge distribution in first grade dentistry students of Jember University academic year 2016/2017 was 106 students (89,1%) in good category and DMF-T score of 53 students or 44.5% in very high category.The results of data analyzed by Spearman correlation test could be concluded that there was a significant relation between dental caries and oral health knowledge of first grade Dentistry students Jember University academic year 2016/2017 with moderate correlation strength (-0.460).

Keywords : Dental caries, First grade dentistry students, Oral health knowledge
Uji Sitotoksisitas Ekstrak Pektin Limbah Kulit Buah Kopi Robusta (Coffea canephora) pada Kultur Sel Fibroblas Pulpa Gigi Manusia (Cytotoxicity Effect of Pectin Extract from Coffea Robusta (Coffea canephora) Fruit Peels on Human Dental Pulp Fibroblasts Cel
Authors: Muslihah Kharishah , Sumono Agus , Fatmawati Dwi Warna Aju 
Published: May 2018

Background: Coffee has a by-product (waste product) that generated from coffee processing. Coffee fruit's peels contains active compound, that is pectin. Pectin has several benefits in health, as a regeneration of hard and soft tissue that can be applied in dentistry and pectin has the potential as an anti-cancer substance. Pectin as a biomaterial must have biocompability. Biocompatibility of the material can be tested by cytotoxicity test by MTT method on human dental pulp fibroblasts cell culture. Objective: To know the toxicity of extract pectin from coffee robusta fruit peels on human dental pulp fibroblasts cell culture. Method: This research is a experimental laboratory with post-test only control group design. Culture of fibroblast cells at the well was exposed by pectin extract for 24 hours, then each well was given MTT and incubated for 4 hours. The effects of cytotoxicity were measured by calculating cell viability (%). Data were analyzed using Probit test, One-way ANOVA followed by LSD. Result: Each group has a cell viability value above 50%. Conclusion: Extract pectin from Robusta coffee fruit peel's had no cytotoxic effect on human dental pulp fibroblsts cell culture

Keywords: coffe robusta fruit peels, cytotoxicity, human pulp fibroblst cell culture, pectin
Issues in Contemporary Management of Secondary Schools in Benue State of Nigeria
Authors: Timothy Alabar, T. , Richard Gbande, I. , Deborah Lim, T. 
Published: May 2018

The world is undergoing nothing less than a major revolution in the way people spend their time and thought on the future of their endeavors. Perhaps, the most important mental and spiritual principle ever discovered is that you become what you think about most time and the actions and inactions you put in place in managing the resources available to you. In view of the fact that resources abound everywhere, they may have little or no value unless you pull out the essentials peculiar to your needs and apply it appropriately. The management of these resources can make you happy or sad, distracted or depressed, popular or unpopular, confident or insecure, positive or negative, successful or unsuccessful, powerful or powerless, victim or victor, a hero or a coward. The management style adopted by an executive determines the level employees feel and the seeds of success that will be planted. As the world moves from the era of things to the mental age, it will be only those that maximally apply the most impressing management principles that will scale the navigational flexibilities of our time. It is on the strength of this that this study is designed conceptually to unveil issues of contemporary management of secondary schools in Benue state of Nigeria. The paper is therefore structured in the following sub-headings: introduction, types of management styles, types of motivational programmes in the workplace, team building, and tips for team building, challenges of teamwork and a conclusion is drawn.
Patient Profiling Can Identify Spondylolisthesis Patients at Risk for Conversion from Nonoperative to Operative Treatment
Authors: Passias Peter G. , Poorman Gregory , Lurie Jon , Zhao Wenyan , Morgan Tamara , Horn Samantha , Bess Robert Shay , Lafage Virginie , Gerling Michael , Errico Thomas J. 
Published: May 2018

Background:
Factors that are relevant to the decision regarding the use of surgical treatment for degenerative spondylolisthesis include disease-state severity and patient quality-of-life expectations. Some factors may not be easily appraised by the surgeon. In prospective trials involving patients undergoing nonoperative and operative treatment, there are instances of crossover in which patients from the nonoperative group undergo surgery. Identifying and understanding patient characteristics that may influence crossover from nonoperative to operative treatment will aid understanding of what motivates patients toward pursuing surgery.

Methods:
Patients with degenerative spondylolisthesis who were randomized to nonoperative care in a prospective, multicenter study were evaluated over 8 years of enrollment. Two cohorts were defined: (1) the surgery cohort (patients who underwent surgery at any point) and (2) the nonoperative cohort (patients who did not undergo surgery). A Cox proportional hazards model, modeling time to surgery, was used to explore demographic data, clinical diagnoses, and patient expectations and attitudes after adjusting for other variables. A subanalysis was performed on surgery within 6 months after enrollment and surgery >6 months after enrollment.

Results:
One hundred and forty-five patients who had been randomized to nonoperative treatment, 80 of whom crossed over to surgery, were included. In analyzing baseline differences between the 2 cohorts, patients who underwent surgery were younger; however, there were no significant difference between the cohorts in terms of race, sex, or comorbidities. Treatment preference, greater Oswestry Disability Index score, marital status, and no joint problems were predictors of crossover to surgery. Clinical factors, including stenosis, neurological deficits, and listhesis levels, did not show a significant relationship with crossover. At the time of long-term follow-up, the surgery cohort showed significantly greater long-term improvement in health-related quality of life (p < 0.001). The difference was maintained throughout follow-up.

Conclusions:
Neurological symptoms and diagnoses, including listhesis and stenosis severity, did not predict crossover from nonoperative care to surgery. Attitudes toward surgery, greater Oswestry Disability Index score, marital status, and no joint problems were independent predictors of crossover from nonoperative to operative care. Certain demographic characteristics were associated with higher rates of crossover, although they were connected to patient attitudes toward surgery.

Level of Evidence:
Prognostic Level II. See Instructions for Authors for a complete description of levels of evidence.
Reduction of Blood Loss by Tranexamic Acid Following Total Hip and Knee Arthroplasty
Authors: Gianakos Arianna L. , Hurley Eoghan T. , Haring R. Sterling , Yoon Richard S. , Liporace Frank A. 
Published: May 2018

Background:
This study involved a meta-analysis of 36 published studies to examine the efficacy of intravenous (IV) and intra-articular (IA) tranexamic acid (TXA) in reducing blood loss, drain output, thromboembolic complications, and hospital stay following total hip and total knee arthroplasty. This study also evaluated whether treatment with a combination of both IA and IV TXA has an effect on these outcomes. Lastly, this study attempted to analyze the method and technique of TXA administration in order to establish a best practice for its use in reducing overall blood loss in arthroplasty procedures.

Methods:
MEDLINE, Embase, and the Cochrane Library database were screened. Studies comparing IV TXA with IA TXA or with combined IV and IA TXA were included. Data including total blood loss, drain output, thromboembolic complications, and hospital stay, where available, were analyzed using meta-analysis with fixed effects. Results are presented as the standardized mean difference (SMD), and meta-regression was employed to explore plausible demographic contributions to heterogeneity.

Results:
Twenty-eight randomized controlled trials, 3 prospective cohort studies, and 5 retrospective cohort studies with 5,499 patients were included in this review. IA administration during total knee arthroplasty showed a significant advantage in terms of total blood loss (SMD = −0.14, 95% confidence interval [CI] = −0.027 to −0.02, I2 = 78.2%) and drain output (SMD = −0.30, 95% CI = −0.43 to −0.18). There was no significant difference between IV and IA administration in total hip arthroplasty. Combined IA plus IV TXA was associated with a significant reduction in blood loss versus IV TXA alone in both total knee arthroplasty and total hip arthroplasty. IV TXA dosing varied, as 14 (39%) of the studies used a weight-based approach while 22 (61%) used a standard dose. Twenty-seven (96%) of 28 studies of IA administration used standard dosing while 1 study followed a weight-based protocol. There was no difference in symptomatic thromboembolic complications, with overall rates in total knee arthroplasty and total hip arthroplasty of 1.0% and 1.0% for IV administration and 1.1% and 0.3% for IA administration, respectively. There was no difference in length of hospital stay for IV versus IA TXA administration.

Conclusions:
IA TXA, either alone or in conjunction with IV TXA, reduces total blood loss and/or drain output in total knee arthroplasty and total hip arthroplasty. Optimal methodology remains to be clarified; however, there are substantial economic benefits of utilizing either IV or IA TXA, with greater cost benefits when using IA TXA.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Sagittal Spinal Alignment in Adult Spinal Deformity
Authors: Iyer Sravisht , Sheha Evan , Fu Michael C. , Varghese Jeffrey , Cunningham Matthew E. , Albert Todd J. , Schwab Frank J. , Lafage Virginie C. , Kim Han Jo 
Published: May 2018

* Changes in spinal alignment trigger several compensatory changes in the pelvis and lower extremities to maintain upright posture. Activating these mechanisms of compensation may require increased energy expenditure to maintain upright posture.* The Scoliosis Research Society-Schwab Adult Spinal Deformity (ASD) classification system allows for a uniform classification and discussion of ASD. A higher sagittal deformity classifier is associated with increased disability.* Age-related changes in spinal alignment are important to consider when setting alignment goals for deformity correction. Less-aggressive correction should be considered in older patients because of their increased risk for complications.* A structured approach to the treatment of ASD consists of 6 steps: (1) find and quantify the driver of deformity, (2) evaluate how deformity impacts global alignment, (3) define alignment targets, (4) determine spinal flexibility, (5) choose a surgical strategy, and (6) execute this strategy intraoperatively in a controlled fashion.
Return and Volatility Spillovers Effects: Study of Asian Emerging Stock Markets
Authors: Roni Bhowmik , Abbas Ghulam , Wang Shouyang 
Published: May 2018

Abstract
This paper examines the extent of contagion and interdependence across the six Asian emerging countries stock markets (e.g., Bangladesh, China, India, Malaysia, the Philippine, and South Korea) and then try to quantify the extent of the Asian emerging market fluctuations which are described by intra-regional contagion effect. These markets experienced both fast growth and key upheaval during the sample period, and thus, provide potentially rich information on the nature of border market interactions. Using the daily stock market index data from January 2002 to December 2016 (breaking the 15 years data set into three sub periods; pre-crisis, crisis, and post crisis periods); particularly make attention to the global financial crisis of 2007∼2008. The return and volatility spillovers are modeled through the GARCH (generalized autoregressive conditional heteroscedasticity), pairwise Granger causality tests, and the forecast error variance decomposition in a generalized VAR (vector auto regression) models. This paper shows that volatility and return spillovers behave very differently over time, during the pre-crisis, crisis, and post crisis periods. Importantly, Asian emerging stock markets interaction is less before the global financial crisis period. The return and volatility spillover indices touch their respective historical peaks during the global financial crisis 2007∼2008, however Bangladeshi market faces this condition in 2009∼2010.
Predicting Trend of High Frequency CSI 300 Index Using Adaptive Input Selection and Machine Learning Techniques
Authors: Kong Ao , Zhu Hongliang 
Published: May 2018

AbstractHigh-frequency stock trend prediction using machine learners has raised substantial interest in literature. Nevertheless, there is no gold standard to select the inputs for the learners. This paper investigates the approach of adaptive input selection (AIS) for the trend prediction of high-frequency stock index price and compares it with the commonly used deterministic input setting (DIS) approach. The DIS approach is implemented through computation of technical indicator values on deterministic period parameters. The AIS approach selects the most suitable indicators and their parameters for the time-varying dataset using feature selection methods. Two state-of-the-art machine learners, support vector machine (SVM) and artificial neural network (ANN), are adopted as learning models. Accuracy and F-measure of SVM and ANN models with both the approaches are computed based on the high-frequency data of CSI 300 index. The results suggest that the AIS approach using t-statistics, information gain and ROC methods can achieve better prediction performance than the DIS approach. Also, the investment performance evaluation shows that the AIS approach with the same three feature selection methods provides significantly higher returns than the DIS approach.
Design of an Optimal Preview Controller for Dual-Rate Linear Discrete-Time Systems
Authors: Guo Yujian , Liao Fucheng 
Published: May 2018

Abstract
A dual-rate preview control strategy for a type of discrete-time system is proposed based on the theory of multirate control. First, by using the discrete lifting technique, the general dual-rate discrete-time system is converted into a single-rate augmented system. On this basis, the augmented error system is constructed by introducing a first-order difference operator and the previewable reference signal. Then the tracking problem is transformed into a regulator problem of the augmented error system. The optimal preview control law of the augmented error system is obtained by using standard linear quadratic optimal preview control theory, and then the optimal preview controller of the original system is derived. In addition, the necessary and sufficient conditions for the controller are given. Finally, simulation results show the effectiveness of the proposed method.
Identification, Characterization and Molecular Modelling Studies of Schistosoma mansoni Dihydrofolate Reductase Inhibitors: From Assay Development to Hit Identification
Authors: Teles Andre Lacerda Braga , Silva Roseane R. , Ko Michelle , Ferreira Glaucio Monteiro , Pita Samuel da Rocha , Trossini Gustavo Henrique Goulart , Carvalho Paulo , Castilho Marcelo Santos 
Published: May 2018

Introduction: Schistosoma mansoni is responsible for virtually all reported cases of schistosomiasis
in Latin America and the emergence of praziquantel- and oxaminiquine-resistant strains
makes it urgent to develop new schistosomicide agents. Dihydrofolate reductases (DHFR) from bacteria
and protozoan parasites are considered validated macromolecular targets for this goal, but S. mansoni
DHFR (SmDHFR) has been largely overlooked. To fill this gap in knowledge, the present work describes
optimized conditions to carry out thermal shift assays with SmDHFR, as well as a balanced kinetic
assay that supports 2,4-diaminopyrimidine derivatives as SmDHFR inhibitors. The most potent
inhibitor (2a) shows a large shift of the melting temperature (ΔTm = + 8 ± 0,21 ºC) and a low micromolar
IC50 value (12 ± 2,3 μM). Both thermal shift and classical kinectic assay suggest that 2a binds to the
substrate binding site (competitive inhibition mechanism). This information guided docking and molecular
dynamics studies that probed 2a interaction profile towards SmDHFR.

Conclusion:
In conclusion, this work not only provides standardized assay conditions to identify
SmDHFR inhibitors, but also describes the binding profile of the first low micromolar inhibitor of this
macromolecular target.