bluuebunny/crossref_metadata_2025_split huggingface dataset:
Delayed Internal Fixation of Distal Radius and Bimalleolar Ankle Fractures Does Not Increase Surgical Time
Authors: Chopra Aman , Hoogervorst Paul , Marmor Meir 
Published: February 2019

Introduction:
It is commonly believed that delay in fracture fixation of more than two weeks results in increased Surgical Time (ST), due to scar and callus formation at the fracture site. Reducing ST can lower hospital costs and decrease radiation exposure.

Methods and Results:
A retrospective chart review was conducted to investigate whether early fracture care (up to 2 days after injury) results in decreased ST and radiation exposure compared to delayed fracture care (> 14 days after injury) for distal radius and bimalleolar ankle fractures. A total of 581 radius and ankle fractures that underwent surgical fixation between 2014 and 2017 were identified from the OR registry. Cases with only a single volar locking plate for the distal radius and constructs consisting of 2 medial malleolar screws, third tubular plate, and up to 1 syndesmotic screw for the ankle were included. The mean ST for distal radius cases done up to 2 days after injury was significantly greater than ST for distal radius cases done > 14 days after injury (125.78±29.75 minutes versus 105.83±24.82 minutes respectively , p=0.06). The mean ST for ankle fracture cases done less than 2 days did not differ from ST for ankle fracture cases done > 14 days after injury (140.86±28.15 minutes versus 173.22±39.98 minutes respectively, p=0.06).

Conclusion:
There was no significant difference in radiation exposure. Delaying surgery for distal radius and bimalleolar ankle fractures > 14 days after injury does not seem to significantly affect the duration of surgery or radiation exposure.
Haruskah Aku Bekerja? (Studi Fenomenologi Keputusan Bekerja pada Pemuda Penyandang Disabilitas di Empat Wilayah di Jawa Tengah)
Authors: Prastowo Fuji Riang , Pudyastuti Irmaningsih , Dewantara Bangkit Rygen 
Published: February 2019

Coping is one form of strategy to deal with stigma and all forms of social pressure that lead obstacles to the growth of young people with disabilities. In this case, coping can be interpreted as a person's effort to overcome the obstacles experienced with certain strategies. In the context of persons with disabilities, the community often views persons with disabilities as a weak marginal group as being dependant to family so that there is no demand to work like humans in general. In addition, there are little opportunity for them to work in the formal sectors causes many of them to be coping with their own efforts for being independent. Therefore, this paper seeks to explore more about coping strategies carried out by youth with disabilities to decide to work. This paper comes from the results of field research with phenomenological qualitative methods in May-June 2018 through FGD and in-depth interviews conducted in four regions in Central Java Province namely Demak Regency, Semarang City, Semarang Regency, and Boyolali Regency. The results of the study indicate that the decision to work or not work from young people with disabilities comes from the response of external factors. Coping is then born into three level : the appraisal-focused level, emotions (the emotion-focused), and actions (problem-focused), which are not linear but can occur differently for each individual depending on the context of growth and development.
Perfil y prácticas educativas del docente orientado a la innovación en las escuelas de negocios en México
Authors: Farías Martínez Gabriela María , Lavín Verastegui Jesús 
Published: February 2019

Es de especial trascendencia para las escuelas de negocios en México afrontar las demandas sociales y de calidad académica de la educación superior. Ante el desafío del cambio, el profesor es el actor central en los procesos de innovación educativa. El objetivo principal de este trabajo de investigación exploratorio- descriptivo, fue conocer las características del perfil y de las prácticas educativas de un profesor innovador en las escuelas de negocios en México. Para lograr este objetivo se combinaron técnicas de investigación cualitativas y cuantitativas, aplicadas a académicos y directivos de las instituciones afiliadas a la ANFECA. Los resultados sugieren que la creatividad, la incorporación de la tecnología y el trabajo colegiado son elementos esenciales para promover la innovación educativa en las disciplinas contables y administrativas en México.
La escritura de textos en colaboración. Una práctica de construcción de representaciones sociales en el aprendizaje de las ciencias
Authors: Gálvez Díaz Víctor Armando 
Published: February 2019

En este artículo se describen las representaciones sociales de la ciencia, construidas entre los alumnos integrantes de tres equipos de trabajo, pertenecientes a diferentes escuelas del nivel medio superior, ubicadas en varios estados de México y con características socioculturales diversas. Se analizan los elementos que constituyen la representación de la ciencia de cada equipo, la forma en que participan las posturas epistemológicas individuales en su construcción, así como las pautas o estilos de colaboración de cada uno de los equipos. Para identificar las representaciones de la ciencia, tanto individuales como de equipo, se pidió a los alumnos analizar y resolver en colaboración un problema relacionado con la construcción del conocimiento científico.
Enseñanza de capacidades comunicacionales en estudiantes y profesionales de la salud: situación actual y perspectivas
Authors: Grilo Ana 
Published: February 2019

Actualmente es ampliamente aceptado que la promoción de la relación del profesional de la salud con su paciente conduce al incremento de la calidad de la atención. La investigación sobre los beneficios de la comunicación eficaz condujo a algunos autores a considerar a la comunicación como la herramienta más importante para la atención de la salud. Como consecuencia, desde comienzo de los años noventa, las escuelas médicas, principalmente del mundo occidental, han aumentado el interés en el desarrollo de las capacidades de comunicación. Este trabajo partió de la investigación bibliografía realizada a través de la b-on. Las palabras clave utilizadas fueron: comunicación profesional de salud-enfermo, entrenamiento capacidades en comunicación, estudiantes y salud. El análisis de los diversos programas de capacitación en materia de capacidadde comunicación destinados a estudiantes y profesionales de la salud permitió constatar que existe una enorme variabilidad y falta de consistencia entre los diferentes programas de capacitación actualmente disponibles. La mayoría de los estudios incluía información insuficiente sobre las capacidades de comunicación que se enseñaría a los participantes. Pese a la situación actual, se señalan algunas directrices para el futuro de la enseñanza de estas capacidades a nivel de la enseñanza de pre y pos graduación en el área de la salud.
PENGELOLAAN MUTU BIJI KAKAO PETANI PERKEBUNAN RAKYAT MELALUI TEKNOLOGI FERMENTASI UNTUK MEMPEROLEH NILAI EKONOMI YANG LEBIH BAIK
Authors: Manalu Radot 
Published: February 2019

AbstrakPenelitian ini fokus untuk membahas peningkatan mutu biji kakao melalui teknologi fermentasi dalam pascapanen perkebunan kakao rakyat, khususnya di Sulawesi Selatan. Hasil penelitian menunjukkan bahwa para petani di Sulawesi Selatan belum memperhatikan mutu karena pada umumnya menjual biji kakao hasil pertaniannya yang belum difermentasi. Biji kakao melalui proses teknologi fermentasi akan menghasilkan cita rasa khas coklat, dengan aroma yang baik dan bermutu tinggi sesuai standard pasar internasional. Jika petani perkebunan kakao rakyat melakukan inovasi teknologi fermentasi, akan mendapatkan nilai tambah dengan selisih harga sekitar Rp 3.000 – Rp 5.000 karena harga biji kakao fermentasi lebih tinggi dari harga biji kakao yang tidak difermentasi. penelitian menggunakan metode kualitatif dengan pendekatan deskriptif. Data yang digunakan dalam penelitian ini meliputi data primer dan data sekunder. Data sekunder diperoleh dari berbagai sumber informasi antara lain: buku, jurnal, data statistik, dan kebijakan berupa peraturan pemerintah sesuai dengan substansi permasalahan dan pembahasan dalam penelitian. Sedangkan data primer diperoleh melalui wawancara dengan responden dan narasumber terpilih. Pengambilan sampel penelitian dilakukan melalui teknik purposive sampling. Responden terpilih ditentukan dengan kriteria: kelompok tani, pedagang pengumpul, dan pedagang besar dan industri. Analisis data dilakukan dengan pendekatan kualitatif ekspoloratif dengan kerangka penelitian manajemen pengelolaan biji kakao pasca panen.
Pharmaceutical study & preliminary analysis of Sheetala Parpati
Authors: Chandra Namitha R. , Karjagi Satish P. , Hussain Gazala 
Published: February 2019

The Parpati kalpana is a thin flake form of mercurial preparation which is unique in the field of Rasashastra. It is one among the Chaturvidha Rasayana and Agnisthayi Murchita Parada Bandha i.e., Pota Bandha of Parada. Sheetala parpati is an Ayurvedic medicine that comes under Parpati kalpana, used in the treatment of difficulty in urination, urinary calculi, dyspepsia, etc. There are two different references of Sheetala Parpati where the ingredients and method of preparation are different. In the present work an attempt has been made to prepare both the varieties of Sheetala parpati along with its analytical study. It is mainly indicated in Mutrakricchra (Dysurea) and other diseases like Amlapitta (Hyperacidity), Udarashoola (Abdominal pain), Ajeerna (Indigestion), Yakritvikara (Hepatic disorder), etc.
Keywords: Parpati kalpana, Chaturvidha Rasayana, Sheetala Parpati, Mutrakricchra (Dysurea)
Formulation and in-vitro evaluation of theophylline sustained release tablet
Authors: Gaware Ravi U , Tambe Sujit T , Dhobale Shankar M , Jadhav Suresh L 
Published: February 2019

The aim of present study was to prepare sustained release tablet of Theophylline so as to prolong its elimination time and at the same time to keep cost of the formulation minimum. In this study ethyl cellulose and Eudragit are used in the formulation to sustain the release of Theophylline. Ethyl cellulose and Eudragit are added at the granulation step to form a sustained release coating around each granule. Different batches were designed one after another on trial and error basis to get the optimum drug release upto 12 hours.
Keywords: Theophylline, ethyl cellulose, Eudragit, sustained release, coating, tablet.
Comparative Phytochemical investigation and Antioxidant study of Narcicuss tazetta, Nymphaea mexicana zucc. And Indigofera heterantha.
Authors: Sabreen Saba , Mubashir Hussain Masoodi Mubashir Hussain Masoodi 
Published: February 2019

The study was intended to investigate the presence of phytoconstituents in the bulbs of Narcicuss tazetta, flowers of the plant Nymphaea mexicana, and roots of Indigofera heterantha. The present study provides evidence that methanolic extracts of Narcicuss tazetta, Nymphaea mexicana and Indigofera heterantha contain important compounds with marked bioactivity. Maximum phenolic content was observed in Nymphaea mexicana and maximum flavonoid content was observed in extract of Indigofera heterantha.
Keywords: Phytoconstituents, Antioxidant, Nymphaea mexicana, Narcicuss tazetta, Indigofera heterantha
Dermal application of lactic acid based cream of a non pathogenic Kocuria marina (BMKO1) strain against Epidermophyton floccosum (MTCC 613) symptomatic excision mice model
Authors: Dash Soumya S , Pattnaik Smaranika 
Published: February 2019

The aim of this study was to evaluate the antifungal efficacy of Kocuria marina (BMKo1) derived Lactic acid against Epidermophyton floccosum (MTCC-613) infections induced on male Swiss Albino mice model (Mus musculus). For this purpose, the isolated strain was subjected to ‘flask fermentation’ and the Lactic acid produced as fermentation product, was quantified and analysed. Prior to preclinical test, healthy mice models of approximately 8 weeks old and 25-30 gm (weight) were subjected to intra-dermal administration for a period of 15 days to test for toxicity. Mortality, clinical signs, body weight changes were continually monitored. Then the mouse models were inoculated with 100 µl/ml (V/V) of E. floccosum (MTCC-613) spore suspensions following ‘Excision model’. After induction of the infection, the symptomatic mice groups were subjected to topical application of Kocuria lactic acid cream based formulation at a concentration of 1µl/ml (V/V). The naked eye observations were made on the infected lesions till the absolute deduction of infection of excised skin surfaces. The degrees of deduction of infection were converted into scores and the percentages (%) of deduction of infection were calculated and the average value was derived. There were inclusion of positive control (Fluconazole) and negative control (group with infection induced excision, but without any drug application) mice groups for the sake of comparison. Further, with absolute deduction of infection score observed in mice group, applied with Kocuria derived Lactic acid was akin to Fluconazole activity. However, the infection induced mice group was found to be with substantial increase of degree of infection. This study have curtain raised about the anti Epidermophyton infection activity of a cream based Cell free Lactic acid derived from a non pathogenic strain of Kocuria marina on mouse models.
Keywords: Kocuria marina, Epidermophyton floccosum, Lactic acid
Assessment of anti bacterial screening of Pongamia pinnata stem against bacterial species: An In-vitro approach
Authors: Manish Adithya Gadeela , Mounika Nerella , Vasudha Bakshi , Narender Boggula 
Published: February 2019

Numerous studies have shown that aromatic and medicinal plants are sources of diverse nutrient and non-nutrient molecules which protect the human body against various pathogens. Nature has been a source of medicinal agents for thousands of years and a large number of modern drugs have been isolated from natural sources. Herbal medicine is the oldest known healthcare system known to mankind. India has rich medicinal plants of nearly 7500 species. Many medicinal plants were with a long history of use in folk medicine against a variety of diseases. Recently, many researchers have taken a great interest on medicinal plants for their phytochemical constituents and biological activities including anti microbial activity. The anti bacterial activity of the ethanolic crude stem extract of Pongamia pinnata against four bacterial species (Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and Escherichia coli) was investigated, using agar diffusion technique. At concentrations ranging from 10-40 mg/mL, the ethanolic crude extract showed activity against the four bacteria (Pseudomonas aeruginosa, Staphylococcus aureus, Bacillus subtilis and E. coli) from 2 mm-20 mm, after 24 hours incubation. The present study showed the effectiveness of the crude plant extract against the tested bacterial strains and indicates the potential use of the extract as anti bacterial agent for the control of infectious diseases.
Keywords: Pongamia pinnata, anti bacterial activity, agar diffusion technique, bacterial strains, chloramphenicol.
Drug utilization studies among ENT patients in various clinical settings: A comprehensive review
Authors: Rasool Shafiqa , Maqbool Mudasir , Joshi Yogesh 
Published: February 2019

Drug utilization research is thus an all important part of pharmacoepideminology as it explains the extent, nature and determinants of drug exposure. A drug utilization study is a tool for determining the effectiveness of drug use. They have tendency to create sound economic bases for health care. It focuses on various factors related to prescribing, dispensing, and administration of medication and associated events. It is a study which is used for analyzing or describe-quantitatively and qualitatively- the population of users of a given drug (or class of drug) and/or the condition of use (for example, indication, duration of treatment, dosage, previous or associated treatment and compliance). ENT problems have been counted as prominent as well as commonly occurring medical problem for our society. It is a problem of most concern. Drug utilization studies can play a major role to identify the nature of therapy used in their treatment and also helps to promote the rationality and minimizing the errors in the drug therapy. Such kind of studies can be helpful for healthcare practitioners as well as to the society against such health issues. Drug utilization research developed quickly during the following 30 years and soon became a respectable subject for consideration at international congresses in pharmacology, pharmacy and epidemiology. Successful research in drug requires multidisciplinary collaboration between clinicians, clinical pharmacologists, pharmacists and epidemiologists. Without the support of the prescribers, this research effort will fail to reach its goal of facilitating the rational use of drugs. In this review, we will briefly list various Drug utilization studies in ENT Clinical settings.
Keywords: Drug utilization studies, ENT, Prescribing patterns, Rational prescribing, Pharmacoepideminology
Canna indica L. (Cannaceae): A review on phytochemical, medicinal, pharmacological and biological studies
Authors: Yadav Prashant Kumar , O S.S. Sisdia 
Published: February 2019

This review article aims to supply in order which is necessary to assert and look at its pharmacognostic, biological and pharmacological profile. Every part of Canna has valuable properties that can serve humankind so the whole plant can be extensively studied for further research aspects. Considering the extensive uses of C. indica L. roots, leaves and rhizomes, the present article work is an attempt to explore phyto-compounds present in Canna indica L. roots leaves, and rhizomes possibly answerable for unusual pharmacological activities exhibited and thereby therapeutic uses predictable to them. This article mainly emphasized on phytoconstituents present in various parts of Canna indica L. and their corresponding biological and pharmacological activities.
Keywords: Canna indica L., origin, phytoconstituents, biological and pharmacological activities
Comparative bioavailability study of phenytoin in healthy Nepalese volunteers
Authors: Rai DIllisher , Rauniar Gajendra Prasad 
Published: February 2019

Our study aimed to assess and compare the bioavailability of Eptoin 100 mg and Epileptin 100mg tablets in Nepalese healthy volunteers. A randomized, two-treatment cross-over study with two weeks’ wash-out period was conducted in 12 healthy non-smoker and non-alcoholic Nepalese male volunteers over a period of 6 months in the department of Clinical Pharmacology and Therapeutic at B. P. Koirala Institute of Health Sciences, Dharan, Nepal after approval from the Institutional Review Committee. The participants were randomized using sealed envelope system and received a single 100 mg oral tablet of either of the formulations with a two week washout period. Blood samples were collected predose and at regular intervals postdose upto 72 hours. Plasma phenytoin levels were estimated by reverse phase high performance liquid chromatography. The analytical method was validated prior to the start of study. Cmax (Peak Plasma Concentration), Tmax (Time to achieve maximum Plasma Concentration), AUC0-72 (Area under plasma concentration time curve 0 to 72 hours), AUC0-∞ (Area under plasma concentration time curve 0 to ∞) and T½ (Elimination half-life) and Kel (Elimination rate constant) were calculated and 80-120% margin (90% confidence interval) was used to assess bioequivalence. ANOVA test was used to analyze the data at P-value of 0.05. All volunteers completed the study. The log-transformed values of Cmax, Tmax, AUC0-t, and AUC0-∞ of the both formulations were within the specified limits and were bioequivalent according to the regulatory definition of bioequivalence based on the rate and extent of absorption. Both products can be considered equally effective in medical practice.
Keywords: Bioavailability, Bioequivalence, healthy volunteer, Nepal, phenytoin sodium.
Performance Analysis of Healthcare data and its Implementation on NVIDIA GPU using CUDA-C
Authors: Rao Naseem , Tanweer Safdar 
Published: February 2019

In this paper we show how commodity GPU based data mining can help classify various healthcare data in different groups faster than traditional CPU based systems. In addition such systems are cheaper than various ASIC (Application Specific Integrated Circuits) based solutions. Such faster clustering of data could provide useful insights for making successful decisions in case of emergency and outbreaks. Finally, we present conclusion based on our research done so far. In our work we used NVIDIA GPU for implementing an algorithm for healthcare data classification. Speech dissiliency and stuttering assessment can also be addressed through classification audio/speech samples using ANN, k-NN, SVM etc4. Such a faster and economical way to get such insights is of paramount importance. Specifically as a proof-of-concept we have implement k-means algorithm on health care related data set.
Keywords: NVIDIA; GPU; ECG; CPU; ANN.
The Financial Situation of the households in Poland after Implementation of the Programme „Family 500+”
Authors: Bugajewska Joanna 
Published: February 2019

The aim of the present paper is an analysis of the impact of the government economic instrument, the „Family 500+” programme on spending decisions of Polish people. For this purpose, financial conditions of families living in two Polish cities: Radom and Chełm were being observed (in the light of the own diagnosis). As a part of a survey, people were asked questions regarding the amount of monthly family income, savings and credits, types of goods and services purchased owing to the „500+” programme for the benefit of children and young people under 18. The paper ends with conclusions resulting from the conducted research.
Um estudo das formas verbais imperativas em cartas pessoais dos séculos XIX e XX
Authors: Silva Aldeir Gomes da 
Published: February 2019

Este estudo analisa cartas pessoais pernambucanas escritas nos séculos XIX e XX, a fim de verificar o comportamento variável do uso de imperativos nas correspondências, bem como observar quais outras formas não verbais podem e são usadas com objetivo de fazer pedidos, exortações etc., considerando os processos de elipse dos verbos, principalmente nas sessões de captação de benevolência, recomendações e despedida das missivas. No que diz respeito às formas imperativas textualmente marcadas, temos por objetivo verificar quais ações podem ser expressas através dos verbos no contexto das cartas analisadas. Para tanto, baseamo-nos na teoria de Tradição Discursiva (KOCH, 1997; KABATEK, 2006; COSTA, 2012), que caracteriza modelos textuais, social e historicamente convencionalizados, que fazem parte da memória cultural de uma comunidade (LONGHIN, 2014) e abrangem distintos graus de abstração e complexidade de modelos textuais. Além de ser uma rica fonte aos estudos da história das línguas, as cartas pessoais constituem um exemplo eficaz da relação existente entre tradições existentes e inovação no contexto sócio-histórico, e o uso dos imperativos nas correspondências oferece um recorte dessa relação. Para a realização desta análise, foram coletadas 60 correspondências produzidas entre os anos de 1901 e 1969. Para a discussão dos dados, apoiamo-nos nos conceitos da sociolinguística (LABOV, 1994 apud LOPES, 2011) na análise quantitativa das ocorrências (ou não ocorrências) de imperativos nas sessões de captação de benevolência, recomendações e saudações das cartas pessoais. Os resultados desta pesquisa apontam para a constatação de que a variação é “mais sistemática e predizível tanto estrutural quanto socialmente” (LOPES, 2011, p. 365).