bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution of native European spiders follows the prey attraction pattern of introduced carnivorous pitcher plants
Authors: Zander Axel , Girardet Marie-Amélie , Bersier Louis-Félix 
Published: September 2018

AbstractCarnivorous plants and spiders are known to compete for resources. In North America, spiders of the genus Agelenopsis are known to build funnel-webs, using Sarracenia purpurea pitchers as a base, retreat and storage room. They also very likely profit from the insect attraction of S. purpurea. In a fen in Europe, S. purpurea was introduced ~65 years ago and co-occurs with native insect predators. Despite the absence of common evolutionary history, we observed native funnels-spiders (genus Agelena) building funnel webs on top of S. purpurea in similar ways as Agelelopsis. Furthermore, we observed specimen of the raft-spider (Dolmedes fimbriatus) and the pygmy-shrew (Sorex minutus) stealing prey-items out of the pitchers. We conducted an observational study, comparing plots with and without S. purpurea, to test if Agelena were attracted by S. purpurea, and found that their presence indeed increases Agelena abundance. Additionally, we tested if this facilitation was due to the structure provided for building webs or enhanced prey availability. Since the number of webs matched the temporal pattern of insect attraction by the plant, we conclude that the gain in food is likely the key factor for web installation. Our results provide an interesting case of facilitation by an introduced plant for a local predator, which has developed in a very short time scale.
Tracing the phylogenetic history of the Crl regulon through theBacteriaandArchaea genomes
Authors: Santos-Zavaleta A , Pérez-Rueda E , Sánchez-Pérez M , Velázquez-Ramírez D A , Collado-Vides J 
Published: September 2018

AbstractCrl, identified for curli production, is a small transcription factor that stimulates the association of the σSfactor (RpoS) with the RNA polymerase core through direct and specific interactions, increasing the transcription rate of genes during the transition from exponential to stationary phase at low temperatures, and it uses indole as an effector molecule. The lack of a comprehensive collection of information on the Crl regulon makes it difficult to identify a dominant function of Crl and to generate any hypotheses concerning its taxonomical distribution in archaeal and bacterial organisms. In this work, based on a systematic literature review, we identified the first comprehensive dataset of 86 genes under the control of Crl in the bacteriumEscherichia coliK-12; those genes correspond to 40% of the σSregulon in this bacterium. Based on an analysis of orthologs in 18 archaeal and 69 bacterial taxonomical divisions and usingE.coliK-12 as a framework, we suggest three main events that resulted in this regulon’s actual form: (i) in a first step,rpoS, a gene widely distributed in bacteria and archaea cellular domains, was recruited to regulate genes involved in ancient metabolic processes, such as those associated with glycolysis and the tricarboxylic acid cycle; (ii) in a second step, the regulon recruited those genes involved in metabolic processes, which are mainly taxonomically constrained toProteobacteria, with some secondary losses, such as those genes involved in responses to stress or starvation and cell adhesion, among others; and (iii) in a posterior step, Crl was recruited as a consequence of its emergence inEnterobacteriaceae. Therefore, we suggest that the regulon Crl is highly flexible for phenotypic adaptation, probably as consequence of the diverse growth environments associated with all organisms in which members of this regulatory network are present.
Microbial Cells Harboring a Mitochondrial Gene Are Capable of CO2 Capture
Authors: Zhou Yanchao , Ouyang Lan , Yi Xiao , Gan Tao , Qi Jinhuan , Wan Yulin , Wang Yuchuan , An Shanshan , Shi Yunfan , Yang Wei , Chen Wenze , Luo Zhiyao , Li Jing , Luo Jun , Nuertai Xiren , Zhu Xiang , Yang Fan , Zhao Beibei , Zhang Weiwei , Ye Zi-Wei , Zhang Xiaoxiao , Weng Shaoping , Liu Qiuyun , Cao Weiguo , He Jianguo 
Published: September 2018

ABSTRACTGlobal warming is escalating with increased temperatures reported worldwide. Given the enormous land mass on the planet, biological capture of CO2remains a viable approach to mitigate the crisis as it is economical and easy to implement. In this study, a gene capable of CO2capture was identified via selection in minimal media. This mitochondrial gene named asOG1encodes the OK/SW-CL.16 protein and shares homology with cytochrome oxidase subunit III of various species and PII uridylyl-transferase fromLoktanella vestfoldensisSKA53. CO2capture experiments indicate that δ13C was substantially higher in the cells harboring the geneOG1than the control in the nutrition-poor media. This study suggests that CO2capture using engineered microorganisms in barren land can be exploited to address the soaring CO2level in the atmosphere, opening up vast land resources to cope with global warming.IMPORTANCEGlobal warming crisis is deteriorating with increased CO2 levels in the atmosphere each year. Action must be taken before catastrophic consequences occur in the not-so-distant future. Biological capture of CO2 is a feasible approach to alleviate the current crisis. We have identified a mitochondrial gene which demonstrated CO2 utilization capability. Data presented in this study suggest that CO2 capture using engineered microorganisms can be harnessed to address the ever-rising CO2 level in the atmosphere.
The diversity of interaction types drives the functioning of ecological communities
Authors: Miele Vincent , Guill Christian , Ramos-Jiliberto Rodrigo , Kéfi Sonia 
Published: September 2018

AbstractEcological communities are undeniably diverse, both in terms of the species that compose them as well as the type of interactions that link species to each other. Despite this long-recognition of the coexistence of multiple interaction types in nature, little is known about the consequences of this diversity for community functioning. In the ongoing context of global change and increasing species extinction rates, it seems crucial to improve our understanding of the drivers of the relationship between species diversity and ecosystem functioning.Here, using a multispecies dynamical model of ecological communities including various interaction types (e.g. competition for space, predator interference, recruitment facilitation), we studied the role of the presence and the intensity of these interactions for species diversity, community functioning (biomass and production) and the relationship between diversity and functioning.Taken jointly, the diverse interactions have significant effects on species diversity, whose amplitude and sign depend on the type of interactions involved and their relative abundance. They however consistently increase the slope of the relationship between diversity and functioning, suggesting that species losses might have stronger effects on community functioning than expected when ignoring the diversity of interaction types and focusing on feeding interactions only.
Transcytosis maintains CFTR apical polarity in the face of constitutive and mutation-induced basolateral missorting
Authors: Bidaud-Meynard Aurélien , Bossard Florian , Schnúr Andrea , Fukuda Ryosuke , Veit Guido , Xu Haijin , Lukacs Gergely L. 
Published: September 2018

SUMMARYApical polarity of cystic fibrosis transmembrane conductance regulator (CFTR) is essential for solute and water transport in secretory epithelia and can be impaired in human diseases. Maintenance of apical polarity in the face of CFTR non-polarized delivery and compromised apical retention of mutant CFTRs lacking PDZ-domain protein (NHERF1) interaction, remains enigmatic. Here we show that basolateral CFTR delivery originates from biosynthetic (~35%) and endocytic (~65%) recycling missorting. Basolateral channels are retrieved via basolateral-to-apical transcytosis, enhancing CFTR apical expression by two-fold and suppressing its degradation. CFTR transcytosis is microtubule-dependent but independent of Myo5B-, Rab11- and NHERF1 binding to its C-terminal DTRL motif in airway epithelia. Increased basolateral delivery due to compromised apical recycling and accelerated internalization upon impaired NHERF1-CFTR association is largely counterbalanced by CFTR efficient basolateral internalization and apical transcytosis. Thus, transcytosis represents a previously unrecognized but indispensable mechanism for maintaining CFTR apical polarity by attenuating its constitutive and mutation-induced basolateral missorting.
Construction of Feed Forward MultiLayer Perceptron Model For Genetic Dataset in Leishmaniasis Using Cognitive Computing
Authors: Mahalingam Sundar , Kabra Ritika , Singh Shailza 
Published: September 2018

AbstractLeishmaniasis is an endemic parasitic disease, predominantly found in the poor locality of Africa, Asia and Latin America. It is associated with malnutrition, weak immune system of people and their housing locality. At present, it is diagnosed by microscopic identification, molecular and biochemical characterisation or serum analysis for parasitic compounds. In this study, we present a new approach for diagnosing Leishmaniasis using cognitive computing. The Genetic datasets of leishmaniasis are collected from Gene Expression Omnibus database and it’s then processed. The algorithm for training and developing a model, based on the data is prepared and coded using python. The algorithm and their corresponding datasets are integrated using TensorFlow dataframe. A feed forward Artificial Neural Network trained model with multi-layer perceptron is developed as a diagnosing model for Leishmaniasis, using genetic dataset. It is developed using recurrent neural network. The cognitive model of the trained network is interpreted using the maps and mathematical formula of the influencing parameters. The credit of the system is measured using the accuracy, loss and error of the system. This integrated system of the leishmaniasis genetic dataset and neural network proved to be the good choice for diagnosis with higher accuracy and lower error. Through this approach, all records of the data are effectively incorporated into the system. The experimental results of feed forward multilayer perceptron model after normalization; mean square error (219.84), loss function (1.94) and accuracy (85.71%) of the model, shows good fit of model with the process and it could possibly serve as a better solution for diagnosing Leishmaniasis in future, using genetic datasets.The code is available in Github repository:https://github.com/shailzasingh/Machine-Learning-code-for-analyzing-genetic-dataset-in-Leishmaniasis
Resting-state functional connectivity, cortical GABA and neuroactive steroids in peripartum and peripartum depressed women: a functional magnetic imaging and resonance study
Authors: Deligiannidis Kristina M. , Fales Christina L. , Kroll-Desrosiers Aimee R. , Shaffer Scott A. , Villamarin Vanessa , Tan Yanglan , Hall Janet E. , Frederick Blaise B. , Sikoglu Elif M. , Edden Richard A. , Rothschild Anthony J. , Moore Constance M. 
Published: September 2018

ABSTRACTPostpartum depression (PPD) is associated with abnormalities in resting-state functional connectivity (RSFC) but the underlying neurochemistry is unclear. We hypothesized that peripartum GABAergic neuroactive steroids (NAS) are related to cortical GABA concentrations and RSFC in PPD as compared to healthy comparison women (HCW). To test this, we measured RSFC with fMRI and GABA+/Creatine (Cr) concentrations with proton magnetic resonance spectroscopy (1H MRS) in the pregenual anterior cingulate (pgACC) and occipital cortices (OCC) and quantified peripartum plasma NAS. We examined between-group differences in RSFC and the relationship between cortical GABA+/Cr concentrations with RSFC. We investigated the relationship between NAS, RSFC and cortical GABA+/Cr concentrations. Within the default mode network (DMN) an area of the dorsomedial prefrontal cortex (DMPFC) had greater connectivity with the rest of the DMN in PPD (peak voxel: MNI coordinates (2, 58, 32), p=0.002) and was correlated to depression scores (peak HAM-D17 voxel: MNI coordinates (0, 60, 34), p=0.008). pgACC GABA+/Cr correlated positively with DMPFC RSFC in a region spanning the right anterior/posterior insula and right temporal pole (r=+0.661, p=0.000). OCC GABA+/Cr correlated positively with regions spanning both amygdalae (right amygdala: r=+0.522, p=0.000; left amygdala: r=+0.651, p=0.000) as well as superior parietal areas. Plasma allopregnanolone was higher in PPD (p=0.03) and positively correlated with intra DMPFC connectivity (r=+0.548, p=0.000) but not GABA+/Cr. These results provide initial evidence that PPD is associated with altered DMN connectivity; cortical GABA+/Cr concentrations are associated with postpartum RSFC and allopregnanolone is associated with postpartum intra-DMPFC connectivity.
Interactome comparison of human embryonic stem cell lines with the inner cell mass and trophectoderm
Authors: Stevens Adam , Smith Helen , Garner Terence , Minogue Ben , Sneddon Sharon , Shaw Lisa , Keramari Maria , Oldershaw Rachel , Bates Nicola , Brison Daniel R , Kimber Susan J 
Published: September 2018

AbstractHuman embryonic stem cells (hESCs) derived from the pluripotent Inner cell mass (ICM) of the blastocyst are fundamental tools for understanding human development, yet are not identical to their tissue of origin. To investigate this divergence we compared the transcriptomes of genetically paired ICM and trophectoderm (TE) samples with three hESC lines: MAN1, HUES3 and HUES7 at similar passage. We generated inferred interactome networks using transcriptomic data unique to the ICM or TE, and defined a hierarchy of modules (highly connected regions with shared function). We compared network properties and the modular hierarchy and show that the three hESCs had limited overlap with ICM specific transcriptome (6%-12%). However this overlap was enriched for network properties related to transcriptional activity in ICM (p=0.016); greatest in MAN1 compared to HUES3 (p=0.048) or HUES7 (p=0.012). The hierarchy of modules in the ICM interactome contained a greater proportion of MAN1 specific gene expression (46%) compared to HUES3 (28%) and HUES7 (25%) (p=9.0×10−4).These findings show that traditional methods based on transcriptome overlap are not sufficient to identify divergence of hESCs from ICM. Our approach also provides a valuable approach to the quantification of differences between hESC lines.And Manchester Academic Health Sciences Centre
Aspirin treatment does not increase microhemorrhage size in young or aged mice
Authors: Chan Sandy , Brophy Morgan , Nishimura Nozomi , Schaffer Chris B. 
Published: September 2018

AbstractMicrohemorrhages are common in the aging brain and are thought to contribute to cognitive decline and the development of neurodegenerative diseases, such as Alzheimer’s disease. Chronic aspirin therapy is widespread in older individuals and decreases the risk of coronary artery occlusions and stroke. There remains a concern that such aspirin usage may prolong bleeding after a vessel rupture in the brain, leading to larger bleeds that cause more damage to the surrounding tissue. Here, we aimed to understand the influence of aspirin usage on the size of cortical microhemorrhages and explored the impact of age. We used femtosecond laser ablation to rupture arterioles in the cortex of both young (2-5 months old) and aged (18-29 months old) mice dosed on aspirin in their drinking water and measured the extent of penetration of both red blood cells and blood plasma into the surrounding tissue. We found no difference in microhemorrhage size for both young and aged mice dosed on aspirin, as compared to controls (hematoma diameter = 104 +/- 39 (97 +/- 38) μm in controls and 109 +/- 25 (101 +/- 28) μm in aspirin-treated young (aged) mice; mean +/- SD). In contrast, young mice treated with intravenous heparin had an increased hematoma diameter of 136 +/- 44 μm. These data suggest that aspirin does not increase the size of microhemorrhages, supporting the safety of aspirin usage.
White Spot Syndrome Virus and the Caribbean Spiny Lobster, Panulirus argus: Susceptibility and Behavioral Immunity
Authors: Ross Erica P. , Behringer Donald C. , Bojko Jamie 
Published: September 2018

AbstractThe Caribbean spiny lobster Panulirus argus is susceptible to infection by Panulirus argus Virus 1 (PaV1), the only virus known to naturally infect any lobster species. However, P. argus is able to mitigate PaV1 transmission risk by avoiding infected individuals. White Spot Syndrome Virus (WSSV) has a particularly wide host range. WSSV has not been documented in wild populations of spiny lobsters, but has been experimentally transmitted to six other lobster species from the genus Panulirus spp. While WSSV has been detected intermittently in wild populations of shrimp in the Caribbean region, the risk to P. argus has not been evaluated. Potential emergence of the disease could result in fisheries losses and ecological disruption. To assess the risk to P. argus, we tested its susceptibility to WSSV via injection and waterborne transmission. We also tested whether healthy lobsters can detect and avoid conspecifics with qPCR-quantifiable WSSV infections. We found P. argus to be highly susceptible to WSSV via intramuscular injection, with mortality reaching 88% four weeks post inoculation. Panulirus argus was also susceptible to WSSV via waterborne transmission, but WSSV burden was low after four weeks via qPCR. Behavioral assays indicated that P. argus can detect and avoid conspecifics infected with WSSV and the avoidance response was strongest for the most heavily infected individuals – a response comparable to PaV1-infected conspecifics. Panulirus argus is the first spiny lobster found to be susceptible to WSSV in the Americas, but it is possible that a generalized avoidance response by healthy lobsters against infected conspecifics provides a behavioral defense and may reduce WSSV infection potential and prevalence. Such avoidance may extend to other directly transmitted pathogens in spiny lobster populations preventing them from becoming common in their population.Author SummaryErica P. Ross is a PhD candidate at the University of Florida, studying the disease ecology of the Caribbean spiny lobster, with a focus on chemosensory ecology. Donald C. Behringer is an associate professor at the University of Florida and his research focuses on disease ecology, epidemiology, and fishery ecology, with a focus on crustaceans and other marine invertebrates. Jamie Bojko received his PhD from the University of Leeds and is currently a post-doctorate associate at the University of Florida studying experimental and systemic crustacean pathology.
Enhancing earthquake resilience of communities: an action by women’s groups in Nepal
Authors: Shrestha Nisha , Shrestha Surya Narayan , Parajuli Bhubaneswari , Dixit Amod Mani , Upadhyay Bijay Krishna , Khanal Om Kala , Sen Oli Khadga 
Published: September 2018

Purpose
Nepal is exposed to frequent earthquakes. There is a felt need for promoting disaster risk reduction action at community level, promoting existing community cohesion for use in disaster preparedness and replication of positive experiences. Involvement of women has been identified as one of the effective ways to motivate and mobilize communities to reduce disaster risks and enhance disaster preparedness. The paper aims to discuss these issues.

Design/methodology/approach
Frontline program was implemented in the four communities of Chandragiri municipality during 2015 with support from GNDR. Preparing the local risk profile and the action plans to reduce those identified risk was the main approach of the Frontline program.

Findings
During the Frontline survey, the community identified earthquake as the top threat in the community and non-structural mitigation as one of the priority actions. The members of the women network started advocating for earthquake safe communities and implementing the risk reduction measures. This action has developed understanding of the process, scientifically and systematically, and boosted their confidence with important new technical skills and new leadership roles in their community to mitigate the earthquake risk.

Originality/value
This case study records the experience of the women’s group in Nepal using their NSM learning in their own houses to reduce vulnerability. They started vulnerability reduction with their own kitchens and bedrooms by fastening their cupboards, frames, freezes, gas cylinders, etc. This led to implementing the mitigation measures in their locality and outside their community. This has been a step toward achieving a safer community through safer houses and schools.
Delay factors of the schedule of strategic industrial projects
Authors: Sweis Rateb , Moarefi Alireza , Hoseini-Amiri Seyyed-Mahmoud , Moarefi Soad 
Published: September 2018

Purpose
The purpose of this paper is to report the results of a survey undertaken to identify and rank factors that are responsible for delay in the schedule of strategic industrial projects in Iran.

Design/methodology/approach
The survey covered 40 factors identified by previous literature and modified by 20 project professionals to fit the Iranian industrial culture. These factors were grouped into six major categories. For each category, the Shannon entropy weighting technique was applied.

Findings
The analysis of the 64 returned out of 87 randomly distributed questionnaires revealed that “sanctions” from political group, “cash flow problems” from financial group, “equipment availability and failure” from technical group, “project manager competence” from managerial group, “material procurement” from procurement group and “unqualified workforce” from human resource group were ranked as the highest contributing factors.

Originality/value
The findings of this study are of practical use for project professionals and experts seeking to improve the schedule performance of industrial projects.
How E-WOM motivations vary by hotel review website
Authors: Belarmino Amanda Mapel , Koh Yoon 
Published: September 2018

PurposeBased on equity theory, this paper investigates if guests write on different review websites because of different internal motivations. Furthermore, it examines the moderating effect of service’ exceeds, neutral, negative, and service recovery–on the relationship between motivations and type of website to write reviews.Design/methodology/approachTo exam if the star ratings of the same hotels were significantly different across hotel, online travel agency, and third-party review websites, this study collected 12,000 star ratings from 40 hotels across the US and conducted t-tests. A survey of 1,600 US travelers was administered to uncover the motivations for writing on different websites/website combinations. Four different scenarios were used to test the moderating effect of service: exceeds, neutral, negative, and service-recovery. These responses were analyzed using backwards stepwise regression.FindingsStar ratings for the same hotel do differ among the three websites; hotel is the highest and third-party is the lowest. There are seven distinct groups of guests. Guests are motivated to write reviews to balance inequitable relationships. They decide which website/website combination best improves the equity relationship. This research indicates that guests’ choice of website is based on different internal motivations. The moderating effect of the service experience was significant.Originality/valueThis paper contributes to the literature by examining different motivations to write online reviews by website. Prior research typically examined one website or aggregated results from multiple websites, ignoring website specific differences. This can help hoteliers to understand why initiatives to promote reviews on certain websites may be unsuccessful.