bluuebunny/crossref_metadata_2025_split huggingface dataset:
The link of diet and exercise habits of the inhabitants of Pärnu city with body mass index
Authors: Õun Kandela , Übner Monika 
Published: June 2018

This article gives an overview of the health behaviour survey of the adult population of the city of Pärnu, which was conducted in 2016. The results of the survey were used for compiling of the city health profile. The funder was the Pärnu city government. The authors focused on the links between the body mass index, diet and physical activity. The survey was carried out among the residents of the city of Pärnu aged 16–64 years. The questionnaire was filled by 506 respondents. Such a large survey had not been carried out in the city of Pärnu previously. In 2011 and 2014 two studies involving whole Estonia were conducted, in which the percentage of the respondents from Pärnu was too small to make further conclusions.
The study results revealed that 65% of respondents ranked their health good or very good, and that was an improvement compared to the previous survey made five years ago. Breakfast was important for respondents, and 86% of them had it every morning or on most days. 49% of respondents were of normal weight by body mass index and 47% were overweight or obese, and these numbers showed a 20% change for better health compared to the previous study. From April to September, 45% of respondents rode a bicycle to work. In their free time, 60% did it for at least 15 minutes per day. Women walked to the workplace more often than men. Men were more overweight and ate more white bread than women. Underweight respondents ate an average of one slice of white bread per day, while others consumed it twice less on average. There was a significant but small correlation between age and BMI (r=0.31), respondents with vocational education had the highest average BMI. Obese persons and respondents with poor physical fitness were less active than normal-weight persons.
Medea and Argonautics: Medicine, pharmacy, toxicology
Authors: Shengelia Ramaz 
Published: June 2018

According to mythical heritage, Medea, a daughter of the king of Colchis (Western Georgia, 13th century BC), famous for her beauty, was very wise and closely associated with plant lore, concoction of medicines, and medical activities. She knew various forms of remedies for internal and external use, respiratory, and so forth. In her therapeutic arsenal, there were medical remedies for a variety of uses: for treatment of various diseases, soporifics, poisons, ointments, miraculous and magical substances as well.
Medea prepared the poisons by using special processing of medical remedies – extraction, infusion/tincture, thermal, mechanical, or chemical exposure, or concentration. The principle, according to which the modern medicine is developing, is contraria contrariis curantur (CCC), or contraries are cured, or allopathic medicine. At present, the priority still belongs to CCC. This is the direction that modern medicine and pharmacy throughout the world are following today.
The way of effective realization of this principle is a strong chemical source. The stronger the source, the more effective the result. This thesis is based on two major ways of realization of the CCC principle – suppressing and compensating therapy where achieving an effect without a potent substance would not be possible.
Toxicology and pharmacy were formed in the Roman Empire at the beginning of our era and are associated with the King of Pontus, a descendant of Colchis – Mithridates VI Eupator. Such a notion as the medicine/drug appeared in the Roman period. The authors do not describe the plant, animal or mineral resources but the product – the characteristics of the drug.
Thus, Medea is not only considered a pioneer of cosmetics, hematology, surgery, toxicology, and other areas but also the founder of the way for effective implementation of the main principle of modern medicine and the donor of word root medicine. Afterwards, the term acquired a broader generalization and consequently become a synonym of medical art.
Barriers and Pathways to Providing Long‐Acting Reversible Contraceptives in Massachusetts Community Health Centers: A Qualitative Exploration
Authors: Janiak Elizabeth , Clark Jill , Bartz Deborah , Langer Ana , Gottlieb Barbara 
Published: June 2018

CONTEXTStructural barriers to the provision of long‐acting reversible contraceptive (LARC) methods at community health centers have been identified in quantitative research, but the processes and behaviors by which center staff respond to these barriers are poorly understood.METHODSFocus group discussions were conducted with clinical, support and administrative staff at three Massachusetts community health centers between April 2014 and January 2015. The centers were purposively selected to constitute a sample with diverse characteristics. Overall, 57 individuals participated in seven focus groups. Data were analyzed inductively using a modified grounded theory approach, and typical pathways to obtaining LARC methods were identified.RESULTSCommunity health center staff provided contradictory descriptions of their facilities’ protocols and practices. Patients’ pathways to obtaining LARC methods were idiosyncratic and clinician‐dependent, and resulted in patients’ waiting between one week and three months to receive their preferred method. Providers’ individual comfort with and perceived competence in contraceptive counseling often shaped patients’ pathways to care. Overall, staff did not consider same‐day insertion of LARC methods a feasible goal. Counseling protocols, insurance verification practices and logistical challenges in ordering and stocking devices were identified as major barriers to timely placement.CONCLUSIONSEfforts to improve LARC provision at community health centers should include the education of staff in how expeditious placement constitutes clinical best practice and the implementation of infrastructural changes to support staff in efficiently counseling patients, scheduling placements and procuring LARC devices regardless of patients’ insurance coverage.
Genome-Wide Analysis of Circulating Cell-Free DNA Copy Number Detects Active Melanoma and Predicts Survival
Authors: Silva Shobha , Danson Sarah , Teare Dawn , Taylor Fiona , Bradford James , McDonagh Andrew J G , Salawu Abdulazeez , Wells Greg , Burghel George J , Brock Ian , Connley Daniel , Cramp Helen , Hughes David , Tiffin Nick , Cox Angela 
Published: June 2018

Abstract

BACKGROUND
A substantial number of melanoma patients develop local or metastatic recurrence, and early detection of these is vital to maximise benefit from new therapies such as inhibitors of BRAF and MEK, or immune checkpoints. This study explored the use of novel DNA copy-number profiles in circulating cell-free DNA (cfDNA) as a potential biomarker of active disease and survival.

PATIENTS AND METHODS
Melanoma patients were recruited from oncology and dermatology clinics in Sheffield, UK, and cfDNA was isolated from stored blood plasma. Using low-coverage whole-genome sequencing, we created copy-number profiles from cfDNA from 83 melanoma patients, 44 of whom had active disease. We used scoring algorithms to summarize copy-number aberrations and investigated their utility in multivariable logistic and Cox regression analyses.

RESULTS
The copy-number aberration score (CNAS) was a good discriminator of active disease (odds ratio, 3.1; 95% CI, 1.5–6.2; P = 0.002), and CNAS above or below the 75th percentile remained a significant discriminator in multivariable analysis for active disease (P = 0.019, with area under ROC curve of 0.90). Additionally, mortality was higher in those with CNASs above the 75th percentile than in those with lower scores (HR, 3.4; 95% CI, 1.5–7.9; P = 0.005), adjusting for stage of disease, disease status (active or resected), BRAF status, and cfDNA concentration.

CONCLUSIONS
This study demonstrates the potential of a de novo approach utilizing copy-number profiling of cfDNA as a biomarker of active disease and survival in melanoma. Longitudinal analysis of copy-number profiles as an early marker of relapsed disease is warranted.
Semmelweis Ignác és az Orvosi Hetilap
Authors: Kiss László 
Published: June 2018

Abstract: Ignác Semmelweis did not publish his discovery in Vienna – i.e., that the puerperal fever may be prevented by careful washing of the hand in chlorine solution (asepsis) – for ten years. The Medical Weekly started its publications edited by Lajos Markusovszky in Pest in 1857. Semmelweis as a professor of theoretical and practical obstetrics at the University of Pest published a study about puerperal fever in the first volume, and Hungarian physicians became familiar with Semmelweis’ opinion from this medical journal. Semmelweis was not only an author of the Medical Weekly, but he also edited a supplement of the Medical Weekly entitled Gynaecology and Paediatry. The Medical Weekly published regular accounts of the work of the clinic written by lecturers of Semmelweis and articles describing the most interesting cases of the clinic. Orv Hetil. 2018; 159(26): 1065–1070.
O processo de apropriação das tecnologias digitais móveis: uma experiência na formação continuada do professor de matemática
Authors: Prado Maria Elisabette Brisola Brito , Dias Fátima Aparecida da Silva , Padilha Willian Rocha 
Published: June 2018

Este artigo tem por objetivo compreender como um grupo de professores de matemática de uma escola pública pensa e se apropria das Tecnologias Digitais Móveis (TDM), mais especificamente do tablet durante o processo de formação continuada. A pesquisa de natureza qualitativa envolveu a participação de seis professores que atuam no Ensino Fundamental da rede pública. A análise dos dados enfatizou quatro momentos, o primeiro contato para saber o que pensam os professores sobre o uso pedagógico das TDM, a Oficina com o uso das TDM, a prática com os alunos e a reflexão sobre a prática vivenciada. Os resultados mostraram que o processo de apropriação tecnológica é particular, situado e se dá de forma contínua. Portanto, é necessário propiciar a formação do professor tendo como foco a reconstrução do conhecimento profissional na perspectiva do TPACK.
A vivência da metodologia da problematização na formação docente
Authors: Hessel Ana Maria Di Grado , Portella da Costa Marina Moretzsohn , Montenssanti Mathias Maria Otilia José 
Published: June 2018

O texto relata uma pesquisa referente ao uso da Metodologia da Problematização com o Arco de Maguerez, como método de ensino, desenvolvido em duas disciplinas do curso de Pedagogia da PUC/SP. O objetivo da pesquisa foi refletir sobre o ensino e aprendizagem, junto aos alunos do curso, os quais vivenciaram uma experiência didática. É uma pesquisa qualitativa de caráter exploratório. A experiência foi avaliada pelos alunos por meio de fichas avaliativas, postadas no ambiente Moodle. Esse ambiente também serviu como suporte para o desenvolvimento e acompanhamento das diferentes etapas da metodologia de problematização. As respostas oriundas das avaliações discentes subsidiaram a análise e interpretação dos dados que revelaram as aprendizagens concretizadas bem como as contribuições para a formação docente crítica e reflexiva.Palavras-chave: Metodologia da Problematização. Método de Ensino. Formação Docente.
Hz. Lokman’ın Öğütleri ve Antik Mısır’ın Sebayt Metinleri
Authors: MERAL Yasin 
Published: June 2018

Hz.
Lokman’ın Kur’an’daki öğütleri Türkçe ve yabancı dillerde pek çok çalışmaya konu olmuştur. Araştırmacılar, Hz. Lokman’ı farklı medeniyetlerdeki muhtelif bilgelerle özdeşleştirirken öğütleri de bu medeniyetlerdeki bilgelik literatürü içerisinde değerlendirmişlerdir. Bu makalede Hz. Lokman
ve öğütleri, araştırmacıların göz ardı ettiği Antik Mısır ve Sebayt metinleri çerçevesinde ele alınacaktır. Bu çerçevede bu makale, Hz. Lokman’ın Mısırlı bir bilge olabileceğini ve öğütlerinin de Antik Mısır’ın bilgelik literatürü olarak bilinen Sebayt metinlerinde aranabileceğini
iddia etmektedir.
Türk Mitolojisine Ait ‘Kutsal Ana’ İmgesinin Siyasal Antropoloji Bağlamında Değerlendirilmesi
Authors: BAŞTÜRK Efe 
Published: June 2018

Mitoloji, bir toplumun kolektif hafızasının
bilinçaltını oluşturur. Mitolojik göstergeler, yalnızca destansı özellikler
taşımaz; onlar ayrıca bir toplumun politik ve hukuki anlamda nasıl
örgütlendiğine ilişkin ipucu sunarlar. Bu bakımdan bir toplumun politik
örgütlenmesi, kolektif bilinci yapılandıran arketipler vasıtasıyla
anlaşılabilir. Bu çalışma, arketiplerin mitolojik varyantlarına odaklanarak
Eski Türk toplumlarındaki “kutsal Ana” imgesine değinecektir. Eski Türk
toplumlarında kutsal Ana imgesine yüklenen animist anlam, kendisini, anahanlı
politik sistemde göstermektedir. Anahanlık, arkaik Türk toplumunun, bir
taraftan doğa ile bütüncül ilişkisini, diğer taraftan ise bu bütüncül ilişkiden
kaynaklanan siyasal[lık] düzeyini yansıtmaktadır. Anahanlı bir siyasal sistem,
doğa ile kurulan ilişkinin hem imgesel-arketipsel düzeyini, hem de tüm bu
süreçler yoluyla inşa edilen politik-hukuki bir yapıyı işaret eder. Türk
toplumunun arkaik varoluş biçimi olarak anahanlık, kadın imgesine yüklenen
“kutsallık” anlamını, “farklılaşmamış” (doğa ile bütüncül varoluş) bir siyasal
sistem vasıtasıyla kurar. Bu çalışma, siyasal antropoloji perspektifine
dayanarak arkaik Türk toplum yaşamını ilgili arketipler üzerinden tartışmayı
amaçlamaktadır.
Dependence of the Result on the Effectiveness of Performance in the World Women’s Handball Championship 2016
Authors: Križan M. , Mikulič M. 
Published: June 2018

The aim of the thesis was to analyze selected indicators of the game performance of the representative team in the defensive and offensive phases of the Slovak cadets’ game, depending on the result of the match.
Materials and methods. In the thesis, we assumed that we would find a statistically significant relationship between the observed performance indicators and the result of the match. To obtain the research data, we used indirect observation of seven World Championship cadet matches of 2016. We used Hianik (2010) to diagnose game performance. We analyzed selected indicators of the game performance of the representative team of Slovak cadets (n=18), depending on the result of the match.
Results. We found out that the result of the match is influenced by the game performance of the team in the defensive and offensive phases of the game. Furthermore, we have drawn the conclusion that the game result is also influenced by the performance of the goalkeeper (p<0.01).
Conclusions. The thesis highlighted the importance of the game performance of the team both in the defensive and the offensive phases of the game as well as the performance of the goalie in the match. The results obtained showed statistical significance (p<0.01) and proved that the outcome of the match is influenced by the successful team play in attack and defense. Also, the result of the match depends on the goalkeeper’s performance. We recommend using the computer program Hianik (2010) to evaluate the game performance of the team in the game.
Advancing Pharmacy Service using Big Data – Are We Fully Utilising the Big Data’s Potential Yet?
Authors: See Hui-Qi , Chan Jin-Ning , Ling Shu-Jin , Gan Shang-Cheng , Leong Chee-Onn , Mai Chun-Wai 
Published: June 2018

Big data is anticipated to have large implications in clinical pharmacy, in view of its potential in enhancing precision medicine and to avoid medication error. However, it is equally debatable since such a powerful tool may also disrupt the need of pharmacist in healthcare industry. In this article, we commented the contribution of Big Data in various aspects of clinical pharmacy including advancing pharmaceutical care service, optimising drug supplies, managing clinical trials, and strengthening pharmacovigilance. The future direction of the usage of Big Data related to clinical pharmacy will be discussed. This article is open to POST-PUBLICATION REVIEW. Registered readers (see “For Readers”) may comment by clicking on ABSTRACT on the issue’s contents page.
Association of water quality with soil-transmitted helminthiasis and diarrhea in Nueva Santa Rosa, Guatemala, 2010
Authors: Matanock Almea , Lu Xin , Derado Gordana , Cuéllar Victoria M. , Juliao Patricia , Alvarez Maricruz , López Beatriz , Muñoz Fredy , Thornton Andrew , Patel Jaymin C. , Lopez Gerard , Reyes Lissette , Arvelo Wences , Blackstock Anna J. , Lindblade Kim A. , Roy Sharon L. 
Published: June 2018

Abstract
Improved water quality reduces diarrhea, but the impact of improved water quality on Ascaris and Trichuris, soil-transmitted helminths (STH) conveyed by the fecal-oral route, is less well described. To assess water quality associations with diarrhea and STH, we conducted a cross-sectional survey in households of south-eastern Guatemala. Diarrhea was self-reported in the past week and month. STH was diagnosed by stool testing using a fecal parasite concentrator method. We explored associations between Escherichia coli-positive source water (water quality) and disease outcomes using survey logistic regression models. Overall, 732 persons lived in 167 households where water was tested. Of these, 79.4% (581/732) had E. coli-positive water, 7.9% (58/732) had diarrhea within the week, 14.1% (103/732) had diarrhea within the month, and 6.6% (36/545) tested positive for Ascaris or Trichuris, including 1% (6/536) who also reported diarrhea. Univariable analysis found a statistically significant association between water quality and STH (odds ratio [OR] = 5.1, 95% confidence interval [CI] = 1.1–24.5) but no association between water quality and diarrhea. Waterborne transmission and effects of water treatment on STH prevalence should be investigated further. If a causal relationship is found, practices such as household water treatment including filtration might be useful adjuncts to sanitation, hygiene, and deworming in STH control programs.
About the influence of temperature and humidity level on pulse shape parameters of positive DC corona discharges in air
Authors: Lühring Ulrich , Wienold Daniel , Jenau Frank 
Published: June 2018

The increasing importance of HVDC transmission systems requires the development and evaluation of suitable basic approaches regarding the partial discharge diagnosis. Although diverse promising approaches are identified, recent research is focused on standard atmospheric conditions. Due to the fact that this is just partly consistent to real operating conditions, additional research is required. Focusing on the time domain analysis of corona discharges, occurring under positive DC voltage stress in air, a measurement method for investigating the influence of varying atmospheric quantities is presented. Measurements are carried out for five different relative humidity levels in the range of 20 % to 95 % and for four different temperature levels in the range of 20 °C to 65 °C. As characterizing pulse shape parameters, the rise time, the pulse width and the fall time are determined as well as the apparent charge. The gained values are compared to each other and reconciled with physical processes.
Desarrollo desigual y trabajo potenciado en la eurozona
Authors: Boundi Chraki Fahd 
Published: June 2018

<p>El objetivo de la presente investigación consiste en ofrecer evidencia empírica<br />que apoye la hipótesis, según la cual el desarrollo desigual de la eurozona es explicado por las diferencias en la cantidad empleada de trabajo potenciado en relación con el trabajo social medio de la región. Para tal efecto se construyó un panel de datos dinámico conformado por los siete principales países de la eurozona con sus respectivos sectores manufactureros para el periodo 2000-2014. La prueba de causalidad de Granger apunta que las disparidades intrasectoriales en la compensación del capital están provocadas por los niveles relativos de los costos laborales unitarios reales, la intensidad del capital y la tasa de acumulación.</p>
Aplicación de un modelo educativo para prevenir parasitosis intestinal<br>Implementing an educational model to prevent intestinal parasitism
Authors: Román Pérez Rosario , Abril Valdez Elba , Cubillas Rodríguez María José , Quihui Cota Luis , Morales Figueroa Gloria Guadalupe 
Published: June 2018

La parasitosis intestinal es causa de morbilidad en niños de 0 a 14 años de edad y está asociada con medidas de higiene y factores psicosociales. En el artículo se muestra el trabjo que se diseñó y aplicó para evaluar un programa de educación para la salud sobre higiene y prevención de parasitosis intestinal en escolares de comunidades marginadas en Hermosillo, Sonora, México. El diseño de investigación fue de grupo de contraste, con evaluación pre/post y toma de muestras coprológicas. El programa se llevó a cabo en dos escuelas de Hermosillo, Sonora, una urbana y otra suburbana durante el ciclo escolar 2010-2011. Los temas trabajados fueron alimentación, prevención de enfermedades, autoestima y cuidado del medio ambiente. Los resultados muestran que la intervención logró cambios positivos a nivel de conocimientos y reducción en la prevalencia de parasitosis intestinal. Abstract Intestinal parasitic infections are associated to morbidity in children of 0-14 years old and measures of hygiene and psychosocial conditions are involved in their transmission. In this study a program of health education and prevention of intestinal parasites was designed, implemented, and evaluated in school children from marginal communities of Hermosillo, Sonora Mexico. The study design consisted of a contrast group, with pre/post assessment and coproparasitological analysis. The educational program was carried out in two schools of Hermosillo, Sonora, one urban and one semi-urban during the school year 2010-2011. The discussed topics were feeding, disease prevention, self-esteem and environmental care. The results showed that the intervention achieved positive knowledge level changes and reduction in the prevalence of intestinal parasites.
Uso de agua en la extracción de gas de lutitas en el noreste de México. Retos de regulación ambiental<br>Water use in shale gas extraction in Northeast Mexico. Environmental regulation Challenges.
Authors: Manzanares Rivera José Luis 
Published: June 2018

El objetivo es analizar el esquema regulatorio de protección ambiental en México ante los retos que el procedimiento de fracturación hidráulica representa para las fuentes de abastecimiento de agua potable locales. Se aplica una metodología descriptiva en el caso de Estados Unidos, país pionero en esta práctica. Los resultados sugieren que el marco regulatorio actual en México presenta barreras significativas frente al procedimiento de fracturación hidráulica, si bien su prohibición no es explícita. Las conclusiones indican que la explotación de gas de lutitas representa un grado elevado de incertidumbre por su impacto ambiental. Se deberán tomar acciones para eliminar a incertidumbre y contribuir al aprovechamiento socialmente responsable de este recurso. Abstract The goal is to analyze the environmental regulatory protection framework in México in face of the challenges that hydraulic fracturing represents for local drinking water sources. A descriptive methodology approach is applied, using the case of the U.S. as reference. The results indicate that current Mexican regulatory framework presents robust measures that highly restrict hydraulic fracturing however; given the complex nature of the process, an explicit ban hasn´t been implemented. Conclusions indicate that the extraction of shale gas presents a high uncertainty level regarding its potential environmental impacts. Therefore efforts to eliminate the uncertainty should be taken to contribute to a socially responsible exploitation of this resource.