bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhancing quality of care for older adults: The age‐friendly health system (4Ms framework) and the role of general medicine physicians as system‐based complexologists
Authors: Higuchi Masaya , Watari Takashi , Ie Kenya 
Published: November 2024

AbstractThe aging population presents critical challenges to global healthcare systems, with Japan expected to have 35% of its population aged 65 or older by 2040. Older adults often experience multimorbidity, cognitive impairments, and physical frailties, increasing healthcare utilization and costs. Traditional medical approaches that focus on organ‐specific diagnoses are insufficient for addressing these multifaceted needs. The Age‐Friendly Health Systems (AFHS) framework, introduced in the U.S., offers a patient‐centered, value‐based approach to geriatric care, encompassing the "4Ms": Mentation, Mobility, Medication, and What Matters. These pillars prioritize cognitive health, physical function, appropriate medication use, and patient values. However, Japan has yet to implement this system widely. The integration of AFHS, with an additional focus on "Multicomplexity" (5Ms), aligns well with the core competencies of General and Family Medicine. This specialty is crucial in leading interdisciplinary efforts to enhance geriatric care, addressing fragmentation and variability in healthcare delivery. To successfully implement AFHS in Japan, general medicine physicians must be trained in managing complex conditions and coordinating care across specialties. This shift toward holistic, patientcentered care is essential for improving outcomes for older adults and reducing healthcare costs. Future research should focus on developing effective strategies for AFHS implementation and training healthcare teams for comprehensive care delivery.
Characterization of the Pathogenic Features of Multiple SARS‐CoV‐2 Pandemic Strains in Different Mouse Models
Authors: Sun Huize , Liu Kunpeng , Yu Baocheng , Zhu Miao , Jia Lijia , Yao Weitong , Chen Zhen , Hao Haojie , Zhang Xueyan , Liu Yi , Liu Haibin , Shan Chao , Huang Fang , Guan Wuxiang 
Published: November 2024

ABSTRACTElucidating the detailed features of emerging SARS‐CoV‐2 strains both in vitro and in vivo is indispensable for the development of effective vaccines or drugs against viral infection. We thoroughly characterized the virological and pathogenic features of eight different pandemic SARS‐CoV‐2 strains, from the WT strain to current circulating sublineage EG.5.1, both in vitro and in vivo. Besides detailed virological features observed in Vero E6 cells, the Omicron variants, from BA.1 to EG.5.1, exhibited enhanced infectious effects to upper respiratory tract in K18 human angiotensin‐converting enzyme (ACE2) (K18 hACE2) transgenic mice. Both XBB.1.9.1 and EG.5.1 presented stronger tropism to brain, which could be the main reason for the increased lethal effects on mice. In addition, the pathogenesis comparisons among all these viruses in C57BL/6JGpt mice indicated that Omicron variant BA.1 and two new sublineages XBB.1.9.1 and EG.5.1 possessed dual tropisms to both human and mice, which were further confirmed by subsequent bioinformatic analyses and actual affinity comparison between viral RBDs and mouse or human receptor ACE2. Furthermore, the immunocompromised BKS‐db mice were found to be more susceptible to Omicron strains compared to C57BL/6JGpt mice, which revealed that viral infectivity was determined by both its affinity to the host receptor and host immunocompetence. Thus, this study not only contributes to a systematic understanding of the pathogenic features of SARS‐CoV‐2 in mice, but also provides new insights to combat potential future surges of new SARS‐CoV‐2 variants.
Staging Approaches to Lymphatic Surgery: Techniques and Considerations
Authors: Salibian Ara A. , Yu Nina , Patel Ketan M. 
Published: November 2024

ABSTRACTLymphatic surgery has demonstrated promising outcomes for the treatment of lymphedema alongside nonsurgical techniques. Physiologic lymphatic surgeries including lymphovenous bypass and vascularized lymph node transplants address the fluid burden in lymphedema whereas reductive surgeries including suction lipectomy and excisional techniques address the fibroadipose component of the disease. Lymphedema patients often present with both fluid and fat components that may require different procedures for optimal results. In addition, the chronic, progressive nature of lymphedema can warrant the need for multiple procedures to address different anatomic areas as well as further improve outcomes. This paper reviews the current literature on staging different or repeated lymphatic procedures and proposes an algorithm to navigate physiologic and reductive lymphatic surgery when multiple procedures are needed to optimize surgical outcomes.
From Virtual Trainers to Companions? Examining How Digital Agency Types, Anthropomorphism, and Support Shape Para‐Social Relationships in Online Fitness
Authors: Feng Ying , Meng Jie , Cheah Jun‐Hwa 
Published: November 2024

ABSTRACTThe role of virtual trainers in online fitness has increasingly captured the attention of consumers and brands as digital technology becomes more interwoven with daily life. This study extends the para‐social relationship theory by developing and testing a research model through five studies that simulate online fitness interactions. In Study 1, we examine the model and find that three characteristics (interactivity, authenticity, and companionship) positively influence consumers' social perceptions (perceived warmth and competence), para‐social relationship building, and intentions to continue using the service. Our findings also reveal that the moderating roles of coach types (human vs. avatar vs. agent) in Study 2, anthropomorphic appearance levels (high vs. low) in Study 3, and the nature of support provided (emotional vs. technical) in Study 4 significantly affect users' social perceptions and their intentions to continue using the service. Interestingly, compared to humans and avatars, using agent coaches requires greater authenticity to strengthen the para‐social relationship. When using low‐anthropomorphic digital agents and avatars, building para‐social relationships more effectively promotes consumers' continued usage intentions. Additionally, the relationship between para‐social relationship building and continued usage intentions was stronger in the emotional support group than in the technical support group. In Study 5, we found that continued usage intention positively affects online fitness subscription behaviors. These findings have implications for integrating digital agencies to enhance consumer experience and engagement in health‐focused digital environments, especially for physical fitness service providers and platform course designers.
Considering Developmental Phenotypes of Suicidality for Young Black Children
Authors: Keenan Kate , Stepp Stephanie , Anderson Leslie A. , Humphries Marisha , Hipwell Alison E. , Mbayiwa Kimberley 
Published: November 2024

ABSTRACTSuicide is currently the 5th leading cause of death among children aged 5–11, a rate that has more than tripled in the last decade, and one that has increased significantly more among Black compared to White children. Specifying early childhood phenotypes of suicidality is critical for prevention of suicidal behavior. Such phenotypes need to be culturally relevant and rigorously tested in Black youth to yield data that will inform prevention science. We used the Interpersonal Theory of Suicide, to guide both the development of a theoretical model and a research protocol to conduct a study on suicidality in young Black children. The model was informed by an ecological adaptation which considers the context of structural, systemic, and interpersonal racism as critical for conceptualizing suicidal risk and identifying factors that reduce the likelihood of suicidal ideation and behaviors among Black youth. Developmental adaptations of IPTS components were based on existing research supporting associations between theoretically similar constructs and early childhood depression and/or later suicidality. Model components include loneliness and lack of family connectedness, low self‐worth and hopelessness, and impulsivity. The components are measured via questionnaires and reactivity to behavioral probes as measured by facial emotion, heart rate variability, and self‐reported mood. Risk and protective factors include exposure to racism and discrimination and racial identity and socialization, respectively. An accelerated, longitudinal design, enrolling 5–9‐year‐old children for 6 repeated assessments over 45 months will allow us to test stability from early childhood to early adolescence. Conducting robust tests of early risk and stability of suicidality in the context of culturally relevant risk factors (e.g., racism) and protective factors (e.g., racial socialization and identity) will contribute to efforts to reverse recent trends in Black youth suicide.
What Is Needed to Determine and Potentially Improve the Clinical Effectiveness and Cost‐Effectiveness of Robot‐Assisted Reconstructive Urinary Tract and Pelvic Floor Surgery?—ICI‐RS 2024
Authors: Wyndaele Michel , Sahai Arun , Kheir George Bou , Hervé François , Ochoa D. Carolina , Rademakers Kevin , van Steenbergen Thomas , Song Qi‐Xiang , Wein Alan , Abrams Paul 
Published: November 2024

ABSTRACTIntroductionRobot‐assisted (RA) surgery has many advantages for urinary tract and pelvic floor reconstruction (UTPFR) but its application is only slowly increasing. Studies are limited in number, patients and follow‐up duration. The low‐volume high‐complexity nature of UTPFR warrants specific research to evaluate the potential role of the RA approach.MethodsDuring its 2024 meeting in Bristol, the International Consultation on Incontinence‐Research Society (ICI‐RS) reviewed the current literature on RA UTPFR. Priority research questions and strategies were explored in a proposal.ResultsFour different topics were discussed. (1) Large multicentre prospective studies on RA UTPFR are needed to evaluate clinical effectiveness and safety. The RA approach needs to be prioritized in specific procedures and patients, to first improve patient care where gains are highest. (2) Models for cost‐utility analysis for RA UTPFR are needed to (re)direct limited resources as efficiently as possible in a quickly changing technological field. (3) A modular curriculum for training UTPFR surgeons to become RA certified needs to be developed, to allow valid interpretation and comparison of outcomes. (4) Technological improvements to address tissue handling, accessibility, efficiency and sustainability are needed. Digitalization can be a gamechanger for RA UTPFR through telesurgery (training and expertize coverage), augmented reality and artificial intelligence providing intra‐operative assistance, assessment and feedback.ConclusionsThe proposal discussed the need for studies on clinical and cost effectiveness, safety, and training curriculum development for RA UTPFR. Recent technological developments hold great promise for RA UTPFR. High‐priority research questions were identified.
Potential Cost‐Saving Model Utilizing Mark Cuban Cost Plus Drug Company for Purchasing Common Otolaryngology Medications
Authors: Buxo Zachary , D. Cramer John 
Published: November 2024

AbstractThe persistent challenge of high pharmaceutical prices has led to the emergence of vertically integrated direct‐to‐consumer distributors like Mark Cuban Cost Plus Drug Company (MCCPDC). This study aims to evaluate a cost‐saving alternative method for medication sourcing. The most frequently prescribed medications by otolaryngologists were identified through analysis of Medicare Part D data, utilizing prescriber type as a filter. Medications were assessed for availability on the MCCPDC website and drug form consistency. Cost analysis was conducted comparing current pharmaceutical spending against MCCPDC pricing. Potential otolaryngology‐driven savings were estimated at $55.6 million and $1 billion if in effect across all specialties. Our findings suggest considerable potential savings for Medicare by purchasing generic medications at MCCPDC prices.
Effects of Music on Pain and Anxiety During Otolaryngology Surgery: A Systematic Review and Meta‐analysis
Authors: Do Kenny , Kawana Eric , Young Kurtis , Ching Harry H. , Bigcas Jo‐Lawrence 
Published: November 2024

AbstractObjectivePatients undergoing surgery commonly experience anxiety during their procedure which can negatively affect surgical outcomes. Music therapy has emerged as a promising noninvasive approach to reducing anxiety particularly in patients undergoing otolaryngology procedures.The objective of this study is to evaluate the effectiveness of music therapy on anxiety and pain during these procedures.Data SourcesPubMed and Embase.Review MethodsA systematic search was conducted using the PRISMA approach to retrieve articles published between 1980 and March 2024. The search terms were applied to PubMed and Embase databases. The search term yielded a total of 669 articles on PubMed and 1027 articles on Embase, 5 of which met the inclusion criteria.ResultsFive studies consisting of 4 randomized controlled trials and one case‐control studies were included in our study, resulting in a total of 381 patients undergoing various otolaryngology procedures. Music therapy was found to reduce preoperative, perioperative, and postoperative anxiety and pain levels compared to control groups. Furthermore, patients who received music therapy experienced improvements in physiological parameters such as heart rate and blood pressure, indicating a positive impact on stress.ConclusionMusic therapy offers a potentially cost‐effective and noninvasive method of reducing anxiety and pain in otolaryngological surgery patients. Our study indicates that music therapy can serve as a valuable addition to traditional pharmacological approaches in managing surgery‐related anxiety and pain. However, more research is needed to standardize music therapy protocols and compare its effect in comparison to other nonpharmacologic and pharmacologic modalities to optimize care for patients.
Percutaneous ultrasound‐guided A1 pulley release utilizing a modified 20‐gauge spinal needle
Authors: Sederberg Mark , Sharma Ragav , Cushman Daniel M. , Finnoff Jonathan T. 
Published: November 2024

AbstractBackgroundTrigger finger is a common cause of hand pain. Though multiple techniques for percutaneous A1 pulley release have been described in the literature, there is a continued need for safe and effective techniques using inexpensive, familiar, and commonly found instruments. This study evaluated outcomes of percutaneous A1 pulley release performed using a novel technique with a modified 20‐gauge spinal needle and ultrasound guidance, with follow‐up outcomes at least 6 months after the procedure.ObjectiveTo evaluate the efficacy and safety of a novel percutaneous A1‐pulley release technique in individuals with trigger finger.DesignRetrospective observational study.SettingPrivate practice outpatient orthopedics clinic.ParticipantsForty digits from 30 unique patients with trigger finger who underwent percutaneous A1 pulley release.InterventionsPercutaneous ultrasound‐guided A1 pulley release performed with a modified 20‐gauge spinal needle.Main Outcome MeasuresThe primary outcome measure was cessation of triggering. Secondary measures examined intraoperative and postoperative pain, postprocedural duration of activity limiting pain, and time to perform the procedure.ResultsImmediate cessation of triggering was achieved in all 40 digits following the procedure, with no recurrence reported at any time at an average follow‐up of 11 months (range 6–32). Patients reported returning to normal activity in 2.75 days. Only one minor complication was reported, tenosynovitis, which resolved with a corticosteroid injection.ConclusionsPercutaneous, ultrasound‐guided A1 pulley release performed with a modified 20‐gauge spinal needle can be safely performed with good outcomes and a rapid return to normal activity.
Adapting piezoelectric ring actuator for early hydration monitoring in cementitious materials
Authors: Soliman N. A. , Omran A. F. 
Published: November 2024

AbstractThere is a need for non‐destructive testing (NDT) methods to evaluate concrete properties in fresh and hardened states. The current study aims to utilize the piezoelectric ring actuator technique (P‐RAT), originally developed for soil applications, to assess the properties of cementitious materials. The research presents the adaptation of P‐RAT to monitor hydration kinetics of cement‐based materials at an early age. The technique measures shear wave velocity (VS) through the materials, offering insights into their behavior during the setting process. The methodology involves a new configuration for the sample holder and new ring dimensions adapted to obtain resonance frequency appropriate for evaluating the cementitious materials at an early age. The study includes an experimental evaluation of different cement paste and mortar mixtures—focusing on examining factors like repeatability, calibration, and ability to determine setting times using both P‐RAT in comparison to traditional methods like the Vicat needle test. The study demonstrates the feasibility of adapting the P‐RAT technique to measure VS along with its potential to provide valuable insights into the cement‐based materials' characteristics during their critical early stages of development.
Trail vs. thicket: Evaluating conservation detection dog performance in varied terrain
Authors: Hassler Kendyl N. , Sylvia Andrea L. , Smith Lisa M. 
Published: November 2024

AbstractUse of detection dogs has emerged as an effective survey method for rare and cryptic species, outperforming traditional methods. However, there is little information available on how survey conditions may affect survey efforts. This study investigates the detection probability, effective sweep width, and search time of a detection dog working on‐lead in varying vegetation and weather conditions in Florida. We established 4 200‐m long transects in habitats with varying vegetation structure: open field, open canopy forest, closed canopy forest, and trail. American mink (Neogale vison) scat was set along each transect, in locations unknown to the detection dog handler, at distances ranging from 0 to 24 m from the transect. Vegetation and weather conditions were recorded for each survey. Between August 2021 and October 2022, we conducted 28 surveys (112 total transect surveys). Across all transects the detection dog located 66% of hidden scats (n = 384). We calculated an effective sweep width of 49 m (24.5 m on either side of the transect) and detection probability decreased with distance from transect line. Contrary to expectations, vegetation structure and weather conditions did not influence detection probability, but vegetation structure did affect search time, an important variable to consider when designing surveys. Search time increased with increases in understory vegetation obstruction and basal area. Conducting surveys on trails showed promise as an effective search method, having similar detection probability to off‐trail transects and faster search times than the closed canopy forest transect. Trail surveys may be particularly useful for areas that would otherwise be impassable, but their effectiveness may vary based on the target species' behavior. Our study underscores the importance of understanding search metrics in conservation detection dog surveys to design effective and appropriate surveys for anticipated field conditions.
Analysis of Event-Centric News Spreading Barriers
Authors: Sittar Abdul , Mladenić Dunja , Grobelnik Marko 
Published: November 2024

AbstractThe nature of the topics being discussed in the news is an essential research question in news spreading since it plays a vital role in individual consumer decisions and political and economic interactions. Also of interest is the question of how the news can be spread more widely across multiple barriers, including linguistic, economic, geographical, political, time zone and cultural. Observing event-centric news, we can see that it has different influences on the public and differs in the way that it spreads. For instance, one would expect news regarding natural disasters such as earthquakes to be mostly objective. Climate change, including global warming and pollution, is a very controversial topic, with political interests of different actors at play. Thus, the reporting is expected to be selective and biased. Finally, when sports intersect with larger societal issues, politics can become intertwined with sports news. Analysing the multi-faceted and spatio-temporal aspects of news coverage can bring insights into what may influence the differences in spreading patterns. This chapter will explain the novel analytical methods used to analyse and understand (1) the news-spreading barriers across different cultures and languages, (2) the multi-faceted and spatio-temporal aspects of the news coverage, and (3) news reporting differences across different political alignments and economic conditions.
Claim Detection in Social Media
Authors: Cheema Gullal S. , Müller-Budack Eric , Otto Christian , Ewerth Ralph 
Published: November 2024

AbstractIn recent years, the problem of misinformation on the web has become widespread across languages, countries and various social media platforms. One problem central to stopping the spread of misinformation is identifying claims and prioritising them for fact-checking. Although there has been much work on automated claim detection from text recently, the role of images and their variety still need to be explored. As posts and content shared on social media are often multimodal, it has become crucial to view the problem of misinformation and fake news from a multimodal perspective. In this chapter, first, we present an overview of existing claim detection methods and their limitations; second, we present a unimodal approach to identify check-worthy claims; third, and lastly, we introduce a dataset that takes both the image and text into account for detecting claims and benchmark recent multimodal models on the task.
From Barcelona to Buenos Aires [and Beyond]: The Millanes Sisters as Migrant Performers, 1880–1920
Authors: McCleary Kristen 
Published: November 2024

AbstractThis chapter examines the lives and careers of Dolores “Lola” and Carlota Millanes, Spanish sisters who migrated throughout the Americas in the late nineteenth and early twentieth centuries. Drawing from playscripts, newspaper, and magazine articles, this chapter pieces together their story, one which reflected transformations of entertainment in the Americas. Lola and Carlota led spectacular lives, evidencing remarkable agency to serve as cultural diplomats, to make their own business decisions, and to head acting companies and even families, rare for women of the era. They were also privileged by an imperial system of race and ethnicity that placed whiteness at the apex of a racial hierarchy. Lola and Carlota refashioned conceptions of work, motherhood, and national identity from Barcelona to Buenos Aires and beyond.
Migration and Exclusion: Ryszard Ordyński—A Theatre ‘Vagabond’
Authors: Prykowska-Michalak Karolina 
Published: November 2024

AbstractAlthough Ryszard Ordyński (1878–1953) is regarded as one of the most significant Polish theatre and film directors, his reputation was eclipsed for a considerable period by other renowned figures. Focusing on Ordyński’s migrations around Europe and the United States between 1910 and 1918, during which he collaborated with Max Reinhardt, directed performances at the Metropolitan Opera in New York, and created noteworthy productions independently, this chapter argues that, despite having multiple opportunities to do so, the Polish theatre failed to make use of his artistic potential or managerial expertise because of both his migration and unfortunate and complicated political circumstances.