bluuebunny/crossref_metadata_2025_split huggingface dataset:
The time for physical exercise and food habits on anumber of students from Pascani National College
Authors: Albu Adriana , Onose Ionuţ , Hodorcă Raluca Mihaela , Moraru Cristina-Elena 
Published: April 2019

Abstract
Nutrition and physical activity are external factors that contributes to the health of young people.Eating too abundant and a short time allocated to physical activity are risk factors for obesity.
Material and Methods: The study was conducted on a group of 79 pupils from the 9th, 10th and 11th grade. To this it was considered the time allotted daily to physical activity (less than 15 min, 15 - 45 minutes, 45 minutes) and were evaluated with a habitsquestionnaire of consumption frequency.Final evaluation will be made separately by class.
Results and Discussion: In most cases young allocate exercise between 15-45 minutes/day (58.22%).Calculated differences are not statistically significant (p> 0.05, fl = 4, χ2 = 7.390) and highlights the lack of concern for the physical activity of the students. Dominant contribution of milk and cheese is just 2-3 times/week and is totally insufficient and potatoes all 2-3 times/week.Instead sweets are consumed 4-7 times/week (64.55%), by two thirds of the young people surveyed. Conclusions: they eat more sweets and do insufficient sport so there are favorable conditions for obesity in the adolescents from the study group.
The relationship between the frequency of physical and sports activities and the body image
Authors: Pop Gabriela Maria , Pop Horea 
Published: April 2019

Abstract
This research aims at highlighting the level of body image perception in Babeş-Bolyai University students in Cluj-Napoca depending on the frequency of practicing physical activities. For this study, 465 questionnaires were applied to students from 13 faculties. The respondents' age was between 18 and 40 years old, most of them ages 19-21. For the statistical data processing, the statistical analysis program SPSS 20 was used and the graphical representations were made using the Microsoft EXCELL 2007 version. To quantify the body image, we used the modified Offer Scale [4]: I kept the first 4 items from the original 5-item scale. The value of the coefficient F = 3,292 at a significance threshold p = 0.038 shows that there is a significant difference between the average scores of body perception based on the frequent or rare of the practicing of physical and sports activities. Reported to the entire sample, it follows that more frequent sports activities determine a more positive body image.
Overweight between perception and reality
Authors: Strava Cristian-Cosmin 
Published: April 2019

AbstractIntroduction. Obesity is a disorder characterized by an amount of body fat over the normal limits. This could be reduced when there are no metabolic disorders with good alimentation and increasing the level of physical activity. In prevention of childhood obesity beside the institution on the field that has the obligation to promote a healthy lifestyle, parents have the main role. They are responsible for the food that their children get and also for their teaching for a healthy lifestyle. However, many times, the parents’ attitude beside the obesity is inappropriate for various reasons. One of them is the fact that parents don’t perceive correctly their children body weight.Theaimof this study is to assess the way a group of parents who have children enrolled to sports activity perceive their children body weight. We also wanted to check the way in which these perceptions are associated with possible attempts to lose weight.Participants and methods: In this study we evaluated 62 girls (average age: 10.29±1.32 years), these being enrolled to a private volleyball club from Timisoara. Testing protocol consisted in height measurement, evaluation of body composition and completing of a questionnaire by parents.Results. In the current research, there exist a few significant differences between the body mass index that was considered the base on which the children were put into different weight categories and the parent’s perception on the body weight of their own children; 38.7 % of the total of the children that were measured were overweight or obese and only 8.04 % were involved in a program that helps weight loss.Conclusion. The vast majority of questioned parents underestimated the real body weight of their children, choosing an inferior weight category, inferior to the real one. These perception errors of the parents affect the level of concern regarding the body weight of the children and, thus, the optimal attitude concerning it.
A review on volleyball injuries
Authors: Reitmayer Hans-Eric 
Published: April 2019

AbstractIntroduction:Unlike other team sports on the court, volleyball lacks physical contact between players, the teams being separated by the net. However, lower limb injuries take place during spiking and blocking trough unintentional and illegal intrusion of a player in the opponent’s court. Due to the specificity of the game, the joints of the upper limbs are also subject to overload.The purposeof this study is to analyze the international literature on injury and trauma in performance volleyball.Methods:We analysed several studies about injuries in performance volleyballwhich were identified using online databases: Google Scholar, EBSCO, Springer, Elsevier, and Scopus.Results:The injury patternshows the ankle sprain as being by far the most common injury in volleyball with a percentage of 31.9%. The knee is the second most injured anatomic site, 17.38% of injuries affecting this joint. Third most frequent injury affects the fingers 13.44%, followed by lower back 12,38% andshoulder trauma 12.18%. The hand is injured in 6.97%, while other injuries were found in 5.25% of cases.Conclusions:The need for in depth analysis of volleyball injuries still persists. Analysing the literature we are comming to understand the mechanisms that produce the injuries with the purpose of finding metods to avoid these unfortunate events before they happen. It is no longer enough to recover from an injury, it must be prevented entirely if possible. Time spent by a player recovering may negatively affect the team's performance.Injury prevention measures must occupy an important place in training. Coaches should take into acount all the factors that influence injury incidence and design the training plan accordingly.
Genetic diagnosis of congenital hypopituitarism by a target gene panel: novel pathogenic variants in GLI2, OTX2 and GHRHR
Authors: Nakaguma Marilena , Correa Fernanda A , Santana Lucas S , Benedetti Anna F F , Perez Ricardo V , Huayllas Martha K P , Miras Mirta B , Funari Mariana F A , Lerario Antonio M , Mendonca Berenice B , Carvalho Luciani R S , Jorge Alexander A L , Arnhold Ivo J P 
Published: April 2019

AimCongenital hypopituitarism has an incidence of 1:3500–10,000 births and is defined by the impaired production of pituitary hormones. Early diagnosis has an impact on management and genetic counselling. The clinical and genetic heterogeneity of hypopituitarism poses difficulties to select the order of genes to analyse. The objective of our study is to screen hypopituitarism genes (candidate and previously related genes) simultaneously using a target gene panel in patients with congenital hypopituitarism.MethodsScreening of 117 subjects with congenital hypopituitarism for pathogenic variants in 26 genes associated with congenital hypopituitarism by massively parallel sequencing using a customized target gene panel.ResultsWe found three novel pathogenic variants inOTX2c.295C>T:p.Gln99*,GLI2c.1681G>T:p.Glu561* andGHRHRc.820_821insC:p.Asp274Alafs*113, and the previously reported variants inGHRHRc.57+1G>A andPROP1[c.301_302delAG];[c.109+1G>A].ConclusionsOur results indicate that a custom-designed panel is an efficient method to screen simultaneously variants of biological and clinical relevance for congenital GH deficiency. A genetic diagnosis was possible in 5 out of 117 (4%) patients of our cohort. We identified three novel pathogenic variants inGHRHR,OTX2andGLI2expanding the spectrum of variants associated with congenital hypopituitarism.
The effect of vitamin D supplementation on plasma non-oxidised PTH in a randomised clinical trial
Authors: Ursem Stan , Francic Vito , Keppel Martin , Schwetz Verena , Trummer Christian , Pandis Marlene , Aberer Felix , Grübler Martin R , Verheyen Nicolas D , März Winfried , Tomaschitz Andreas , Pilz Stefan , Obermayer-Pietsch Barbara , Heijboer Annemieke C 
Published: April 2019

ObjectivePTH can be oxidisedin vivo, rendering it biologically inactive. Non-oxidised PTH (n-oxPTH) may therefore give a better image of the hormonal status of the patient. While vitamin D supplementation decreases total PTH (tPTH) concentration, the effect on n-oxPTH concentration is unexplored. We investigated the effect of vitamin D on n-oxPTH concentration in comparison to tPTH and compared the correlations between parameters of calcium, bone and lipid metabolism with n-oxPTH and tPTH.MethodsN-oxPTH was measured in 108 vitamin D-insufficient (25(OH)D <75 nmol/L) hypertensive patients, treated with vitamin D (2800 IE daily) or placebo for 8 weeks in the Styrian Vitamin D Hypertension Trial (NCT02136771). We calculated the treatment effect and performed correlation analyses of n-oxPTH and tPTH with parameters of calcium, bone and lipid metabolism and oxidative stress.ResultsAfter treatment, compared to placebo, 25(OH)D concentrations increased, tPTH decreased by 9% (P < 0.001), n-oxPTH by 7% (P = 0.025) and the ratio of n-oxPTH/tPTH increased (P = 0.027). Changes in phosphate and HDL concentration correlated with changes in n-oxPTH, but not tPTH.ConclusionstPTH and n-oxPTH decrease upon vitamin D supplementation. Our study suggests that vitamin D supplementation reduces the oxidation of PTH, as we observed a small but significant increase in the non-oxidised proportion of PTH upon treatment. In addition, we found that changes in phosphate and HDL concentration showed a relationship with changes in n-oxPTH, but not tPTH. This may be explained by the biological activity of n-oxPTH. Further research should be carried out to establish the clinical relevance of n-oxPTH.
Single-Cell RNA Sequencing Identifies Candidate Renal Resident Macrophage Gene Expression Signatures across Species
Authors: Zimmerman Kurt A. , Bentley Melissa R. , Lever Jeremie M. , Li Zhang , Crossman David K. , Song Cheng Jack , Liu Shanrun , Crowley Michael R. , George James F. , Mrug Michal , Yoder Bradley K. 
Published: April 2019

Significance Statement
Despite abundant research focused on understanding the importance of mouse renal resident macrophages in homeostatic and disease settings, these findings have unknown relevance to higher-order species, including humans, because markers to identify a similar population of cells across species are lacking. This hinders translating data obtained in animal model systems to human patients. In this study, the authors used a single-cell RNA sequencing approach, followed by validation using flow cytometry, to identify novel markers of mouse resident macrophages and show that these markers also identify a population of macrophages in rat, pig, and human kidney tissue. Over all, their findings serve as an entry point to study candidate kidney resident macrophages across species.

Background
Resident macrophages regulate homeostatic and disease processes in multiple tissues, including the kidney. Despite having well defined markers to identify these cells in mice, technical limitations have prevented identification of a similar cell type across species. The inability to identify resident macrophage populations across species hinders the translation of data obtained from animal model to human patients.

Methods
As an entry point to determine novel markers that could identify resident macrophages across species, we performed single-cell RNA sequencing (scRNAseq) analysis of all T and B cell–negative CD45+ innate immune cells in mouse, rat, pig, and human kidney tissue.

Results
We identified genes with enriched expression in mouse renal resident macrophages that were also present in candidate resident macrophage populations across species. Using the scRNAseq data, we defined a novel set of possible cell surface markers (Cd74 and Cd81) for these candidate kidney resident macrophages. We confirmed, using parabiosis and flow cytometry, that these proteins are indeed enriched in mouse resident macrophages. Flow cytometry data also indicated the existence of a defined population of innate immune cells in rat and human kidney tissue that coexpress CD74 and CD81, suggesting the presence of renal resident macrophages in multiple species.

Conclusions
Based on transcriptional signatures, our data indicate that there is a conserved population of innate immune cells across multiple species that have been defined as resident macrophages in the mouse. Further, we identified potential cell surface markers to allow for future identification and characterization of this candidate resident macrophage population in mouse, rat, and pig translational studies.
Практика первичной профессиональной социализации выпускников школ — потенциальных абитуриентов вуза медицинского профиля
Authors: Корягина Ирина Ивановна , Курылева Наталья Владимировна 
Published: April 2019

<p>В статье обоснована и проанализирована практика профессиональной социализации выпускников школ — потенциальных абитуриентов вуза медицинского профиля в триаде «преподаватель — обучающийся — выпускник / потенциальный абитуриент» в профориентационных мероприятиях. Обозначены основные направления результативной работы с потенциальными абитуриентами в регионах и мероприятиях вузовского уровня. Организовано взаимодействие в системе на основании беседы, анкетирования, просмотра видеоматериалов, психодиагностики, разработки конкретных практических рекомендаций, направляющих познавательные потребности обучающихся. Созданы психолого-педагогические условия для первичной профессиональной ориентации и социализации учащихся школ.</p>
История образования в России: досоветский и советский периоды
Authors: Ситаров Вячеслав Алексеевич 
Published: April 2019

<p>В статье предпринята попытка раскрыть проблему соотношения эффективности образовательных реформ, проводимых в России, а также причин и факторов их возникновения. Период становления и развития образования до 1917 г. отражает личностный характер проводимых реформ, детерминированных деятельностью министров, возглавлявших ведомство народного просвещения в XIX–XX вв., а также общие закономерности и особенности реформистского способа обновления системы образования в соответствии со спецификой исторической эпохи. В последующий после 1917 г. период проводимые реформы в образовании носили государственно-общественный характер, поскольку их целью было воплощение в жизнь коллективных решений партийных съездов, направленных на развитие совершенно новой идеологически направленной советской системы образования. </p><p>Исследование опирается на аналитические материалы, содержащиеся в таких произведениях, как «Исторический обзор деятельности Министерства Народного Просвещения. 1802–1902» (1902); «Очерки истории российского образования: К 200-летию Министерства образования Российской Федерации (2002); «Реформы в России с древнейших времен до конца XX в.» (2016).</p>
Образы Марло и Шекспира в современной киноиндустрии
Authors: Захаров Николай Владимирович 
Published: April 2019

<p>В статье дан критический анализ воплощений образов К. Марло и У. Шекспира в современной киноиндустрии. Связь двух драматургов и, как обычно считают, соперников в поэтическом ремесле может быть установлена только гипотетически и через призму их литературного творчества. Нет исторического подтверждения тому, что они встречались лично, но следы их знакомства с пьесами друг друга обнаруживаются в текстах и поддаются реконструкции.</p><p>Образ К. Марло, трагически и рано погибшего поэта и авантюриста, обычно демонизируется, тогда как образ «человека из Стратфорда» — Шекспира, напротив, чаще романтизируется. Это обусловлено местом, которое оба писателя традиционно занимают в мировом и национальном культурном сознании, литературной и исторической репутацией каждого из них. Применение тезаурусного подхода к интерпретации таких явлений, как шекспиросфера, шекспировская и марловианская индустрии, культ автора и т. д., дает богатый материал для анализа функциональности этих понятий в современном гуманитарном знании.</p>
<i>Incêndios</i>: uma tragédia contemporânea
Authors: De Oliveira Richard Bertolin 
Published: April 2019

Desde 2003, a peça Incêndios, do escritor e diretor libanês Wadji Mouawad, vem obtendo reconhecimento da crítica e conquistando importantes prêmios internacionais, como o Prix de la Francophonie, no Canadá, e o prêmio Molière, na França. No Brasil, também houve uma montagem da peça, em 2013, dirigida por Aderbal Freire-Filho, tendo a atriz Marieta Severo no papel da protagonista Nawal. Em 2016, a montagem brasileira faz sua última temporada. Um dos possíveis fatores pelos quais o espetáculo vem obtendo reconhecimento do público e da crítica onde é apresentado, deve-se à utilização de elementos comuns às antigas tragédias na composição de seu enredo e de sua estética. Sob a perspectiva da intertextualidade, o presente ensaio tem como objetivo analisar tais elementos e as referências à obra Édipo Rei, de Sófocles, aos quais Mouawad recorre para a construção de uma tragédia contemporânea.
Enfermedad de Paget de la mama sin carcinoma ductal asociado: reporte de caso y revisión de la literatura
Authors: Matamoros-Parra Liseth Johana , Vertel-Velásquez Miguel Andrés , Camargo-Villalba Gloria Eugenia 
Published: April 2019

Objetivo: presentar un caso de Enfermedad de Paget (EP) mamaria sin carcinoma ductal asociado y realizar una revisión de literatura respecto a su diagnóstico y tratamiento.Materiales y métodos: mujer de 59 años, con lesión pruriginosa, eritematosa y ulcerada crónica, en pezón izquierdo, de 2 años de evolución, quien recibió inicialmente manejo dermatológico con corticoides tópicos sin mejoría clínica y acude finalmente a una institución de atención primaria en Tunja, Colombia para su diagnóstico, el cual se realizó por biopsia mediante inmunohistoqumica y posterior manejo mediante cuadrantectomía central con patología posquirúrgica negativa para malignidad, sin recurrencia al año de seguimiento. Se realizó una búsqueda en las bases de datos PubMed, SciELO, ProQuest, ScienceDirect y Google Académico con los términos “Paget´s Disease”, “Breast Neoplasms”, “Mammography” “Ultrasonography, Mammary”, “Biopsy” y “Mastectomy”, rastreando artículos de revisión bibliográfica, editoriales, reportes y series de casos clínicos en inglés y español, sin límite de tiempo.Resultados: se incluyeron 11 publicaciones correspondientes a 5 reportes de caso, 3 series de casos, 1 revisión de la literatura a partir de un caso clínico y 2 cartas al editor que describieron casos relacionados con enfermedad de Paget del pezón sin carcinoma asociado. El diagnóstico se fundamentó en la sospecha clínica de la enfermedad con la posterior realización de biopsia de la lesión, la inmunohistoquímica fue útil en el diagnóstico diferencial: El tratamiento varió desde mastectomía hasta resección de complejo areola pezón. La radioterapia también ha sido utilizada.Conclusiones: el diagnóstico de la enfermedad de Paget sin carcinoma ductal asociado se fundamenta en una sospecha clínica temprana y el estudio histopatológico del complejo areola pezón. No hay consenso sobre el manejo de quirúrgico de esta lesión. Se requieren estudios de seguimiento de este subgrupo de pacientes tratado con radioterapia o cirugía conservadora.
Amiodarone-induced thyrotoxicosis type 2: predictors and treatment options
Authors: Ermolaeva A. S. , Biakina O. A. , Sytch J. P. , Kopylov P. Yu. , Fadeev V. V. 
Published: April 2019

Amiodarone-induced type 2 thyrotoxicosis remains a significant problem of modern endocrinology and cardiology. The unique pharmacological character and multifaceted properties of amiodarone explain its high prescription frequency and the leading position among antiarrhythmic drugs. In its turn, cytotoxicity and supra-physiological iodine content in the drug increase the risk of drug-induced destructive thyroiditis. The development of thyrotoxicosis leads to recurrence of cardiac arrhythmias, increased left ventricular dysfunction and manifestations of chronic heart failure. Correct identification of the type of thyrotoxicosis determines the subsequent patient management strategy. Glucocorticoids have been recognized as the first-line treatment among the possible therapy options. Rapid correction of thyrotoxicosis is crucial, especially in elderly patients with severe heart disease. Of interest for practical medicine is the search for specific predictors (deep understanding of the pathogenetic mechanisms) and new possibilities of therapy for amiodarone-induced thyrotoxicosis type 2.
PROBLEM PSIKOLOGIS DAN STRATEGI COPING PELAKU UPACARA KEMATIAN RAMBU SOLO’ DI TORAJA (STUDI FENOMENOLOGI PADA TANA’ BULAAN )
Authors: Marwing Arman 
Published: April 2019

Penelitian ini bertujuan untuk memahami dinamika psikologis subjek dengan cara memahami faktor motivasional individu dari tana’ bulaan miskin dalam melaksanakan upacara rambu solo’, beban keuangan sebagai kejadian menekan yang mereka hadapi, strategi pengatasan masalah dan dampak psikologis pada tana’ bulaan miskin. Penelitian ini adalah penelitian kualitatif dengan pendekatan fenomenologi. Subjek penelitian sebanyak 4 orang yang melaksanakan upacara rambu solo’ tingkat sempurna, sedang, dan minim serta 7 orang informan. Metode analisis mengacu pada Moustakas (1994) yaitu : deskripsi pemahaman fenomena, reduksi dan eliminasi, pengelompokkan tema dan deskpripsi individu terhadap fenomena. Hasil temuan penelitian ini adalah: a) faktor-faktor yang mendorong pelaksanaan upacara rambu solo’ merupakan upaya individu untuk memenuhi kebutuhan dasar dalam dirinya, yaitu kebutuhan untuk survive , love and belonging, power, dan freedom. b) Keputusan terlibat membuat para pelaku menghadapi dampak langsung dan <br /><p>dampak tidak langsung dari beban keuangan rambu solo’. c) Dalam menghadapi beban keuangan rambu solo’ sebagai stresor, Strategi coping yang dilakukan para pelaku, utamanya pelaku upacara rambu solo’ besar, cenderung mengalami penurunan secara bertahap dari coping berfokus pada masalah kemudian beralih pada coping berfokus pada emosi dan dari coping adaptif beralih pada coping maladaptif. (d) dampak psikologis yang ditemukan: stres, ketakutan (kecemasan), depresi ringan. (e) dinamika psikologis pelaku upacara rambu solo’ sangat kompleks, sebagai pilihan dari proses internal, beban keuangan rambu solo’ dinilai subjek sebagai konsekuensi dan untuk itu mereka berupaya mencari kebutuhan-kebutuhan yang sama atau berbeda yang adekuat atas deprivasi kebutuhan dasar dalam dirinya.</p><p> </p>
DINAMIKA PSIKOLOGIS KEKERASAN SEKSUAL: SEBUAH STUDI FENOMENOLOGI
Authors: Fu'ady Muh Anwar 
Published: April 2019

<p>Purpose of this study was to find out how the sexual violence occurs, the psychological impact of sexual violence, and knowing how psychological dynamics of sexual assault victims. Subjects in this study were the two people taken purposively with the criteria had experienced sexual violence. Methodology in qualitative research is phenomenological. There are four processes in a phenomenological approach that is epoche, phenomenological reduction, imaginative variation and synthesis of meaning. Data analysis process involves bracketing, horizonalizing, and meaning units to get the textural description. The results of this study indicate that the psychological impact of the subjects who are victims of sexual violence is the presence of post-traumatic stress disorder. Besides having a psychological impact, psychological dynamics of the subjects in this study also have similarities, but there are some striking differences. The big difference in the impact and psychological dynamics is caused by several factors such as personality characteristics, how to solve problems, how to manipulate cognition, and social support.</p><p> </p>