bluuebunny/crossref_metadata_2025_split huggingface dataset:
The diagnostic and prognostic values of plasma Epstein‐Barr virus DNA for residual cervical lymphadenopathy in nasopharyngeal carcinoma patients: a retrospective study
Authors: Liu Sai‐Lan , Sun Xue‐Song , Li Xiao‐Yun , Tang Lin‐Quan , Chen Qiu‐Yan , Lin Huan‐Xin , Liang Yu‐Jing , Yan Jin‐Jie , Lin Chao , Guo Shan‐Shan , Liu Li‐Ting , Li Yang , Xie Hao‐Jun , Tang Qing‐Nan , Liang Hu , Guo Ling , Mai Hai‐Qiang 
Published: March 2019

AbstractBackgroundCurrently, the diagnosis and treatment of nasopharyngeal carcinoma (NPC) patients with residual cervical lymphadenopathy following radical radiotherapy with or without chemotherapy are challenging. We investigated the prognosis of NPC patients with residual cervical lymphadenopathy and assessed the diagnostic and prognostic values of Epstein‐Barr virus (EBV) DNA in these patients.MethodsThis study included 82 NPC patients who were diagnosed with suspected residual cervical lymphadenopathy following completion of antitumor therapy. Their plasma EBV DNA levels were measured using quantitative polymerase chain reaction (qPCR) before the initiation of treatment and before neck dissection. Fine needle aspiration cytology (FNAC) was performed in 21 patients. All patients had undergone neck dissection and postoperative pathological examination to identify the nature of residual cervical lymphadenopathy. The overall survival (OS), progression‐free survival (PFS), distant metastasis‐free survival (DMFS), and locoregional relapse‐free survival (LRRFS) were calculated using the Kaplan–Meier method and compared using the log‐rank test. The Cox proportional hazards model was used to calculate hazard ratios (HRs) with 95% confidence intervals (CIs). Multivariable analysis was used to estimate the effect of potential prognostic factors on survival.ResultsFollowing a median follow‐up of 52.6 months, compared with patients with negative postoperative pathological findings for residual cervical lymphadenopathy, the patients with positive findings had a significantly lower 3‐year PFS rate (49.9% vs. 83.3%, P= 0.008). Among NPC patients with residual cervical lymphadenopathy, the patients with preoperative plasma EBV DNA > 0 copy/mL had a lower 3‐year PFS rate than did those with no detectable EBV DNA (43.7% vs. 61.1%, P= 0.031). In addition, combining FNAC with preoperative EBV DNA detection improved the diagnostic sensitivity. Multivariable analysis demonstrated that residual cervical lymphadenopathy with positive postoperative pathological result was an independent prognostic factor for PFS and that detectable preoperative plasma EBV DNA was an independent prognostic factor for OS.ConclusionsUsing FNAC combined with preoperative EBV DNA detection improves the sensitivity in diagnosing NPC with residual cervical lymphadenopathy. Compared with patients with undetectable EBV DNA, patients with detectable preoperative plasma EBV DNA have worse prognosis and may require a more aggressive treatment strategy.
Self-Management in Long-Term Prostate Cancer Survivors: A Randomized, Controlled Trial
Authors: Skolarus Ted A. , Metreger Tabitha , Wittmann Daniela , Hwang Soohyun , Kim Hyungjin Myra , Grubb Robert L. , Gingrich Jeffrey R. , Zhu Hui , Piette John D. , Hawley Sarah T. 
Published: March 2019

PURPOSE This randomized clinical trial compared a personally tailored, automated telephone symptom management intervention to improve self-management among long-term survivors of prostate cancer with usual care enhanced with a nontailored newsletter about symptom management. We hypothesized that intervention-group participants would have more confident symptom self-management and reduced symptom burden. METHODS A total of 556 prostate cancer survivors who, more than 1 year after treatment, were experiencing symptom burden were recruited from April 2015 to February 2017 across four Veterans Affairs sites. Participants were randomly assigned to intervention (n = 278) or usual care (n = 278) groups. We compared differences in the primary (symptom burden according to Expanded Prostate Cancer Index Composite-26 [EPIC], confidence in self-management) and secondary outcomes between groups using intent-to-treat analyses. We compared domain-specific changes in symptom burden from baseline to 5 and 12 months among the intervention group according to the primary symptom focus area (urinary, bowel, sexual, general) of participants. RESULTS Most of the prostate cancer survivors in this study were married (54.3%), were white (69.2%), were retired (62.4%), and underwent radiation therapy (56.7% v 46.2% who underwent surgery), and the mean age was 67 years. There were no baseline differences in urinary, bowel, sexual, or hormonal domain EPIC scores across groups. We observed higher EPIC scores in the intervention arm in all domain areas at 5 months, though differences were not statistically significant. No differences were found in secondary outcomes; however, coping appraisal was higher (2.8 v 2.6; P = .02) in intervention-arm patients at 5 months. In subgroup analyses, intervention participants reported improvement from baseline at 5 and 12 months in their symptom focus area domains. CONCLUSION This intervention was well received among veterans who were long-term survivors of prostate cancer. Although overall outcome differences were not observed across groups, the intervention tailored to symptom area of choice may hold promise to improve associated burden.
Cost per insertion and couple year of protection for postpartum intrauterine devices and implants provided during service scale-up in Kigali, Rwanda
Authors: Wall Kristin M. , Ingabire Rosine , Allen Susan , Karita Etienne 
Published: March 2019

Introduction: In two high-volume government hospitals, their two affiliated health facilities, and two additional health facilities, we developed and implemented postpartum intrauterine device (PPIUD) and postpartum (PP) implant promotional counseling and service delivery procedures between May-July 2017 in Kigali, Rwanda. Between August 2017 and July 2018, 9,073 pregnant women received PPIUD/PP implant promotions who later delivered in one of our selected facilities. Of those, 2,633 had PPIUDs inserted, and 955 had PP implants inserted. The goal of the present analysis is to detail implementation expenditures and estimate incremental costs per insertion and couple years of protection (CYP) for PPIUD and PP implant users. Methods: We detail the incremental costs during the implementation from the health system perspective (including both the implementation costs and the cost of contraceptive methods) and use of standard methods to estimate the cost per insertion and CYP for PPIUD and PP implant users. In addition to the incremental costs of labor and supplies, the costs of promotional activities are included. Research costs for formative work were excluded. Results: A total of $74,147 USD was spent on the implementation between August 2017 and July 2018. The largest expense (34% of total expenses) went toward personnel, including doctoral-level, administrative, data management and nurse counseling staff. Training for PPIUD and implant providers and promoters comprised 8% of total expenses. Recruitment and reimbursements comprised 6% of expenses. Costs of implants to the government comprised 12% of the expenses, much higher than the cost of IUDs (1%). Costs per insertion were $25/PPIUDs and $77/PP implant. Costs per CYP were $5/PPIUDs and $20/PP implant. Conclusion: Understanding the cost per PPIUD/PP implant inserted and CYP can help to inform the cost of scaling up PPIUD/PP implant service implementation activities and resource allocation decision-making by the Rwandan Ministry of Health.
Is the synovial fluid cobalt-to-chromium ratio related to the serum partitioning of metal debris following metal-on-metal hip arthroplasty?
Authors: Langton D. J. , Natu S. , Harrington C. F. , Bowsher J. G. , Nargol A. V. F. 
Published: March 2019

Objectives We investigated the reliability of the cobalt-chromium (CoCr) synovial joint fluid ratio (JFR) in identifying the presence of a severe aseptic lymphocyte-dominated vasculitis-associated lesion (ALVAL) response and/or suboptimal taper performance (SOTP) following metal-on-metal (MoM) hip arthroplasty. We then examined the possibility that the CoCr JFR may influence the serum partitioning of Co and Cr. Methods For part A, we included all revision surgeries carried out at our unit with the relevant data, including volumetric wear analysis, joint fluid (JF) Co and Cr concentrations, and ALVAL grade (n = 315). Receiver operating characteristic curves were constructed to assess the reliability of the CoCr JFR in identifying severe ALVAL and/or SOTP. For part B, we included only patients with unilateral prostheses who had given matched serum and whole blood samples for Co and Cr analysis (n = 155). Multiple regression was used to examine the influence of JF concentrations on the serum partitioning of Co and Cr in the blood. Results A CoCr JFR > 1 showed a specificity of 83% (77% to 88%) and sensitivity of 63% (55% to 70%) for the detection of severe ALVAL and/or SOTP. In patients with CoCr JFRs > 1, the median blood Cr to serum Cr ratio was 0.99, compared with 0.71 in patients with CoCr JFRs < 1 (p < 0.001). Regression analysis demonstrated that the blood Cr to serum Cr value was positively associated with the JF Co concentration (p = 0.011) and inversely related to the JF Cr concentration (p < 0.001). Conclusion Elevations in CoCr JFRs are associated with adverse biological (severe ALVAL) or tribocorrosive processes (SOTP). Comparison of serum Cr with blood Cr concentrations may be a useful additional clinical tool to help to identify these conditions. Cite this article: D. J. Langton, S. Natu, C. F. Harrington, J. G. Bowsher, A. V. F. Nargol. Is the synovial fluid cobalt-to-chromium ratio related to the serum partitioning of metal debris following metal-on-metal hip arthroplasty? Bone Joint Res 2019;8:146–155. DOI: 10.1302/2046-3758.83.BJR-2018-0049.R1.
Interleukin-1 receptor antagonist protein (IL-1Ra) and miR-140 overexpression via pNNS-conjugated chitosan-mediated gene transfer enhances the repair of full-thickness cartilage defects in a rabbit model
Authors: Zhao R. , Wang S. , Jia L. , Li Q. , Qiao J. , Peng X. 
Published: March 2019

Objectives Previously, we reported the improved transfection efficiency of a plasmid DNA-chitosan (pDNA-CS) complex using a phosphorylatable nuclear localization signal-linked nucleic kinase substrate short peptide (pNNS) conjugated to chitosan (pNNS-CS). This study investigated the effects of pNNS-CS-mediated miR-140 and interleukin-1 receptor antagonist protein (IL-1Ra) gene transfection both in rabbit chondrocytes and a cartilage defect model. Methods The pBudCE4.1-miR-140, pBudCE4.1-IL-1Ra, and negative control pBudCE4.1 plasmids were constructed and combined with pNNS-CS to form pDNA/pNNS-CS complexes. These complexes were transfected into chondrocytes or injected into the knee joint cavity. Results High IL-1Ra and miR-140 expression levels were detected both in vitro and in vivo. In vitro, compared with the pBudCE4.1 group, the transgenic group presented with significantly increased chondrocyte proliferation and glycosaminoglycan (GAG) synthesis, as well as increased collagen type II alpha 1 chain (COL2A1), aggrecan (ACAN), and TIMP metallopeptidase inhibitor 1 (TIMP-1) levels. Nitric oxide (NO) synthesis was reduced, as were a disintegrin and metalloproteinase with thrombospondin type 1 motif 5 (ADAMTS-5) and matrix metalloproteinase (MMP)-13 levels. In vivo, the exogenous genes reduced the synovial fluid GAG and NO concentrations and the ADAMTS-5 and MMP-13 levels in cartilage. In contrast, COL2A1, ACAN, and TIMP-1 levels were increased, and the cartilage Mankin score was decreased in the transgenic group compared with the pBudCE4.1 group. Double gene combination produced greater efficacies than each single gene, both in vitro and in vivo. Conclusion This study suggests that pNNS-CS is a good candidate for treating cartilage defects via gene therapy, and that IL-1Ra in combination with miR-140 produces promising biological effects on cartilage defects. Cite this article: R. Zhao, S. Wang, L. Jia, Q. Li, J. Qiao, X. Peng. Interleukin-1 receptor antagonist protein (IL-1Ra) and miR-140 overexpression via pNNS-conjugated chitosan-mediated gene transfer enhances the repair of full-thickness cartilage defects in a rabbit model. Bone Joint Res 2019;8:165–178. DOI: 10.1302/2046-3758.83.BJR-2018-0222.R1.
Uso del juego como instrumento evaluador en estudios superiores de ciencias de la salud
Authors: González Pilar , Canet Olga , Robleda Gemma 
Published: March 2019

El uso del juego como innovación docente mejora la motivación de los estudiantes y es una metodología poco desarrollada como proceso de evaluación en el ámbito universitario.Objetivos. 1. Determinar el grado de adquisición de conocimiento de los estudiantes de enfermería en las materias incluidas en la actividad evaluativa «Escape Room» y 2. Conocer el nivel de satisfacción de los estudiantes de enfermería con la actividad evaluativa. Métodos. Estudio observacional, descriptivo y transversal. Se evaluaron los conocimientos, habilidades y la actitud de los estudiantes con la actividad mediante una nota numérica de 0 a 10. Se evaluó la tasa de rendimiento y el grado de satisfacción con un cuestionario específico autoadministrado.Resultados. El conocimiento adquirido por los estudiantes de 1º obtuvo una puntuación de 8,6 y las habilidades y actitudes de los estudiantes de 2º consiguieron una nota promedio de 8,5. La satisfacción con la actividad evaluativa obtuvo puntuaciones de 9,2 para 1º y 7,2 para 2º. Se obtuvieron tasas de rendimiento de 9,1% para 1º y del 100% para los estudiantes de 2º. Conclusiones. El uso del juego como sistema de evaluación para los estudiantes del grado en enfermería ofrece buenos resultados en la valoración de conocimientos, habilidades y actitudes. Los niveles de satisfacción de los estudiantes con la actividad y las tasas de rendimiento obtenidas son excelentes.
X-ray crystal structure of N'-[(1E)-1-(2,4-dihydroxyphenyl)-ethylidene]pyridine-4-carbohydrazide
Authors: Jayaprakash Venkatesan , Timiri Ajay Kumar , Vijayan Viswanathan , Sinha Barij Nayan , Devadasan Velmurugan 
Published: March 2019

Schiffâ€™s base of isonicotinyl hydrazide with 2â€™,4â€™-dihydroxy acetophenone (INH-RA) has been designed and synthesized as a part of library enumeration targeting the NS2B-NS3 protease of Dengue virus. Slow evaporation from methanol results in the formation of monoclinic crystalsÂ C2/c space group with eight molecules in the unit cell (a=20.0165(3) Ã…, b=7.7594(10) Ã…, c=19.4809(3) Ã…, Î±=90 Â°, Î²=111.368(1) Â°, Î³=90 Â° and Z=8).Three dimensional X-ray crystallographic structure of the compound has been determined and refined usingÂ SHELXS-97 and SHELXL-2014, respectively to a final R-value of 4.64%
Branched Coverings and Minimal Free Resolution for Infinite-Dimensional Complex Spaces
Authors: Ballico E. 
Published: March 2019

Abstract
We consider the vanishing problem for higher cohomology groups on certain infinite-dimensional complex spaces: good branched coverings of suitable projective spaces and subvarieties with a finite free resolution in a projective space P(V ) (e.g. complete intersections or cones over finitedimensional projective spaces). In the former case we obtain the vanishing result for H
1. In the latter case the corresponding results are only conditional for sheaf cohomology because we do not have the corresponding vanishing theorem for P(V ).
Bi-Hamiltonian Structure as a Shadow of Non-Noether Symmetry
Authors: Chavchanidze G. 
Published: March 2019

Abstract
The correspondence between non-Noether symmetries and bi-Hamiltonian structures is discussed. We show that in regular Hamiltonian systems the presence of the global bi-Hamiltonian structure is caused by the symmetry of the space of solution. As an example, the well-known bi-Hamiltonian realization of the Korteweg–de Vries equation is discussed.
Inchoatives in causative clothing
Authors: Kastner Itamar 
Published: March 2019

AbstractThe “causative” templateheXYiZin Hebrew is the morphological form of verbs which are usually transitive. I discuss cases in which specific roots give rise to the labile alternation, otherwise unattested in the language. A straightforward analysis is suggested for the majority of cases, based on causativeVoice[+D]$\text{Voice}_{\text{[+D]}}$. This analysis is then extended to account for the labile exceptions, which inform how the idiosyncratic meaning of roots influences syntactic computation.
Çürük belirleme yöntemlerine güncel yaklaşımlar
Authors: BAYRAK Gökçen Deniz , SELVİ-KUVVETLİ Senem 
Published: March 2019

Bir çürük lezyonuna erken aşamada tanı
konulması, diş dokusunun olabildiğince korunmasına katkıda bulunabilecek en uygun
tedavi planının oluşturulmasına olanak sağlar. Diş çürüğünün belirlenmesinde ve
kaydedilmesinde kullanılan sistemler arasında tutarsızlıkların olması,
epidemiyolojik ve klinik çalışmalarda elde edilen sonuçların karşılaştırılabilmesini
zorlaştırmaktadır. Bu nedenle; diş hekimliği eğitiminde, klinik uygulamalarda
ve araştırmalarda kullanılabilecek, çürüğün tüm aşamaları ile
değerlendirilmesini sağlamak amacı ile bir klinik çürük skorlama sistemi olan Uluslararası
Çürük Belirleme ve Değerlendirme Sistemi
(ICDAS)
geliştirilmiştir. Yapılan
toplantılar sonucunda ICDAS kriterleri tekrar gözden geçirilmiş ve bazı
değişiklikler yapılarak ICDAS II kriterleri ortaya konulmuştur. ICDAS II baz alınarak çürüğün doğru şekilde tedavi edilebilmesi ve hastanın
çürük risk grubunun belirlenerek ağız hijyeninin en iyi şekilde sürdürülebilmesi
amacıyla da Uluslararası
Çürük Sınıflaması ve Yönetim Sistemi (ICCMS) geliştirilmiştir. Günümüzde bu sistemler yaygın bir şekilde kullanılmaya
başlanmıştır ve bu sayede diş hekimliğinde girişimsel uygulamaların azalacağı
düşünülmektedir.

Anahtar
kelimeler: diş çürükleri, erken
teşhis, ICDAS, ICCMS
Dev Tükürük Bezi Taşlarının Cerrahi Eksizyonu: İki Vaka Raporu
Authors: DELİLBAŞI Ertan Ali , MAMMADOVA Ulviyya , SİVRİ Damla , GÖKSU Vahit Can , ÖZTÜRK Kübra 
Published: March 2019

Özet

Sialolithiazis,
“sialolit” olarak tanımlanan tükürük bezi taşlarının gelişimi ile oluşan bir
rahatsızlıktır. Sialolitiazis %80
oranında submandibular tükürük bezinin içinde veya duktusunda görülmektedir.
Tükürük bezi hastalıklarının tanısında farklı görüntüleme teknikleri
kullanılabilir. Bu makalede iki farklı
hastanın submandibular tükürük bezin duktusunda teşhis edilen sialolitlerin
cerrahi eksizyonu rapor edilmektedir.
Konik Işınlı Bilgisayarlı Tomografide Maksiller ve Mandibular Süpernümere Dişlerin Lokalizasyonları, Karakteristikleri ve Komplikasyonları
Authors: MENZİLETOĞLU Dilek , ERDUR Emire Aybüke , BAŞTÜRK Funda 
Published: March 2019

Amaç: Süpernümere
dişler, normal diş sayısından fazla olan dişler olarak tanımlanmaktadır. Hem
süt hemde daimi dentisyonda süpernümere dişlere rastlanılmaktadır.
Etiyolojileri tam olarak bilinmemektedir. Genelde gömülüdür ve radyograflarda
tesadüfen görülürler. Bu sunum, süpernümere dişlerin panoramik radyograf ve
konik ışınlı bilgisayarlı tomografi (KBIT) kullanılarak lokalizasyonunu
değerlendirmek ve tedavi yaklaşımlarını sunmaktadır. Gereç ve Yöntemler:Bu retrospektif çalışmada 6273 hastanın
radyografik verileri Necmettin Erbakan Üniversitesi, Diş Hekimliği Fakültesi
Ağız, Diş Çene Cerrahisi ve Ortodonti bölümlerinde incelendi. Süpernümere diş
sayısı, dişin anatomik lokalizasyonu, erüpsiyon durumu panoramik radyografta ve
KBIT’ta incelendi. Bulgular:6273
hastanın 64’ünde (40 erkek, 24 kadın) 66
süpernümere diş teşhis edildi. Hastaların yaş aralığı 9-65 yıl ve yaş ortalaması 22.47 yıldı. 2 hastada (mandibula premolar ve molar bölge) çift
taraflı süpernümere diş vardı. 43 süpernümere diş gömülüydü. Bu dişlerin 33’ü
konik formda, 10’u da odontoma şeklinde ve 23’ü ise diş şeklindeydi.
Süpernümere dişlerin hepsi çekildi. 44 süpernümere diş ortodontik tedavi için
çekildi. 2 hastada maksilla premolar
bölgede görülen süpernümere diş ile birlikte görülen kist enükle edildi,
patolojik teşhis ile dentigeröz kist tanısı konuldu. 14 süpernümere diş
profilaktik olarak çekildi. 6 hastada
anterior bölgede dolgu ve protez yaptıracağı için dişleri çekildi.Sonuçlar:Süpernümere
dişlerin büyük çoğunluğu gömülü olduğundan rutin klinik muayeneler sırasında
teşhis edilememekte ancak komplikasyona neden olduklarında veya radyografik
incelemeler sırasında saptanabilmektedir. KBIT, süpernümere dişlerin şekli ve
lokalizasyonu ile ilgili 3 boyutlu görüntü sağlamaktadır. Ortodontik tedavi görecek hastalarda
süpernümere dişler daimi dişlerin hareketine engel olmaktadır. Erken tanı ve tedavi ilişkili komplikasyonların
önlenmesi açısından önemlidir.Anahtar Kelimeler:Süpernümere
dişler, konik ışınlı bilgisayarlı tomografi, ortodontik tedavi
SEGMENTAL KANİN RETRAKSİYONUNDA PREFABRİKE LADANYİ SPRİNG VE REVERSE CLOSİNG LOOP’UN KARŞILAŞTIRILMASI
Authors: KÖK Hatice , GÖYENÇ Yaşar Bedii 
Published: March 2019

Çekimli
vakalarda maksiller kaninlerin retraksiyonu ortodontik tedavinin esas
safhalarından birisidir. Retraksiyon sonrasında kaninlerin doğru pozisyonda
olmaları fonksiyon, estetik ve stabilite için önemlidir. Edgewise tekniğinde
kaninler iki yolla retrakte edilmektedir. Birinci yöntem sürtünmeli yöntem
olarak da adlandırılır, devamlı ark teli üzerinde kaninlere kuvvet uygulanması
ile ark üzerinde gerçekleştirilen yöntemdir. İkinci yöntemde ise bölümlü arklar
ve springler yardımıyla sürtünmesiz bir şekilde retraksiyon sağlanmaktadır.
Sürtünmesiz sistem ile boşluk kapama yöntemi; bukkal segmental looplar veya
retraksiyon springlerinin kullanımı yardımıyla bilinen M/F oranları oluşturmaya
dayanmaktadır. Ayrıca optimum büyüklükte, nisbeten sabit ve önceden
belirlenebilen kuvvetlerin salınımı öngörülmektedir. Çalışmanın amacı
prefabrike Ladanyi springin, elde bükümü yapılmış olan reverse closing loop ile
kıyaslanması, ankraj dişler ve kaninler üzerinde meydana gelen değişimleri
değerlendirmektir.

Çalışmaya
yaşları 12,51-16,94 yıl arasında ortalama 15,82 yıl olan 9 kız, 3 erkek toplam
12 hasta dahil edilmiştir. Prefabrike Ladanyi spring hastaların sağ
taraflarına, reverse closing loop ise sol tarafına yerleştirilmiştir. Seanslar
4 haftada bir yapılmıştır. Her hastadan referans telleri yerleştirilerek
sefalometrik radyograflar alınmıştır. Periyotlara göre sağ ve sol fark
karşılaştırılmasında 2-bağımsız örnek testi Mann-Whitney U analizi, periyotlar
arası kıyaslama için Friedman testi
kullanılmıştır.

Çalışmamızda
kanin retraksiyonu Ladanyi tarafında 5,15±0,75 ay devam etmiştir. Kanin
retraksiyonu sonrasında molar dişlerde ankraj kaybı, sellanasion düzlemine göre
kaninlerde intruzyon-molarlarda ekstruzyon ve overjette spontan düzelme
gözlenmiştir. Ayrıca kaninlerde distale devrilme, molarlarda meziale devrilme
gözlenmiştir.
Enfoques de género e interculturalidad en salud: una metodología para cubrir la necesidad de su apropiación sostenible en el Perú
Authors: Vincx Laura , Geysels Luc 
Published: March 2019

En el Perú existen grandes brechas de género e interculturalidad, particularmente en el sector salud. Estas brechas dan lugar a discriminación, muertes maternas e infantiles, maltrato y deshumanización de la atención de salud. Para mejorar la calidad sanitaria, el Programa SISTEC usó como metodología dictar talleres en género e interculturalidad; así, organizó 44 en 5 regiones y capacitó a 837 profesionales en salud. Sistematizando la experiencia, varios factores para mejorar los resultados resaltaron, como la selección de participantes, la adecuación cultural y la metodología utilizada. Los talleres impulsaron cambios socio-culturales en el ámbito laboral y personal, pero su sostenibilidad depende de las estrategias de institucionalización. Se concluye que los talleres pueden ser una metodología útil para impulsar la apropiación sostenible de los enfoques de género e interculturalidad, siempre y cuando forman parte de una estrategia holística y adecuadamente planificada donde los talleres sirvan como el punto de partidapara el cambio.