bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing ChatGPT Responses to Common Patient Questions on Knee Osteoarthritis
Authors: Gilmore Nathan , Kushner Jared N. , Redden Anna , Hansen Austin W. , Yerke Hansen Payton , Martinez Lisa 
Published: November 2024

Background Patient education is an important component in providing high quality healthcare, especially in the context of orthopedic surgery. In the current era of continuous technological advancements and the adoption of artificial intelligence in healthcare, the use of online chatbots in patient education is inevitable. The purpose of this paper is to evaluate ChatGPT-3.5’s effectiveness in answering common patient questions about knee osteoarthritis. Methods Ten frequently asked questions were collected from ten separate healthcare institution pages and input into ChatGPT-3.5. The questions were then analyzed for reliability and completeness using the DISCERN instrument and the Journal of the American Medical Association (JAMA) Benchmark criteria. The readability was analyzed using the Flesch Kincaid scoring system. Results Of the ten questions, the average DISCERN score was 51. Three responses were considered good, six were fair, and one was poor. The JAMA Benchmark criteria was zero for all responses. The average Flesch Kincaid grade level score was 29.33, indicating a college grade reading level. Conclusion ChatGPT-3.5 may have the potential to be an informative tool for patients with questions about knee osteoarthritis. It was able to provide fair responses, however, some inquiries required clarification and all responses lacked reliable citations. Furthermore, the responses were written at a college grade reading level, which limits its utility. Therefore, proper patient education should be conducted by orthopedic surgeons. This highlights the need for patient education resources that are both accessible and comprehensible.
Vasculitis leucocitoclástica asociada a infección: a proposito de un caso y revisión de literatura
Authors: Romero Escamilla Diana Verónica , Jumaan Torres Mariam Hussein , Peralta y Serna Julieta 
Published: October 2024

La vasculitis leucocitoclástica es la vasculitis cutánea más frecuente se caracterizan por un síndrome vasculítico secundario a una reacción de hipersensibilidad tras la exposición frente a un antígeno exógeno (fármacos, microorganismos o proteínas) o endógeno (ADN, inmunoglobulinas o antígenos tumorales). La biopsia demuestra inflamación de pequeños vasos sanguíneos, más prominente en las vénulas postcapilares, aunque también afecta arteriolas y capilares. Se le denomina desde el punto de vista anatomopatológico, vasculitis leucocitoclástica, debido a la presencia del fenómeno de leucocitoclasia (fragmentación de los núcleos de los neutrófilos o “polvillo nuclear”) en la pared de los vasos y alrededor de los mismos. Por lo que el diagnóstico histopatológico a través de biopsia se debe realizar lo antes posible para descartar otras causas como enfermedades sistémicas, neoplásicas o infecciosas. Se presenta el caso presenta el caso de una femenina que inicia con lesiones vasculiticas secundaria a una neumonía.
FORMAÇÃO SUPERIOR EM EXTENSÃO AGRÁRIA EM MOÇAMBIQUE: ANÁLISE E LEVANTAMENTO DE NECESSIDADES
Authors: De Moçambique Universidade Católica 
Published: November 2024

Moçambique é um país com enormes potencialidades para a prática de uma agricultura sustentável e produtividade reconhecível. Estima-se que o país possui um pouco mais de 36 milhões de hectares de terra arável, dos quais apenas 10% em uso e 90% destes pelo sector familiar. Porém, nos últimos 15 anos, uma, em cada duas crianças moçambicanas, é assolada por desnutrição crónica, cujos efeitos vão desde mortes infantis, privação entre as gerações, má saúde e baixos aproveitamentos escolares (Rich, 2016). Sendo a Economia essencialmente agrária, com uma contribuição ligeiramente superior a um quarto do produto interno bruto do País, produtividade baixa e emprega pouco mais de 80% da força de trabalho total, fica claro a necessidade de uma assistência técnica em Extensão Agrária, por via de formação profissionalizada e especializada dos principais intermediários e agentes de intervenção agrária – os extensionistas. O estudo procurou analisar e levantar as necessidades para implementação do curso de Licenciatura em Extensão Agrária, em parceria com a Sassakawa Africa Foun for Extension Education (SAFE) e o Ministerio da Agricultura e Segurança Alimentar (MASA), tendo respondido a pergunta sobre que necessidades os pequenos agricultores, extensionistas, empregadores, instituições de ensino superior vocacionadas a area de agricultura e outras agentes de extensão, gostavam de ver supridas com o curso de Licenciatura em Extensão Agrária? Quanto à abordagem, enquadra-se no género de estudos quantitativos (quanto à abordagem), exploratória (quanto ao objectivo) e aplicada (quanto à sua natureza), por gerar conhecimentos para a aplicação prática, busca de solução de problemas específicos para além de envolver verdades e interesses locais e específicos. Foram inqueridos 4 (quatro) grupos de agentes, tendo, de forma unânime, considerado relevante e necessário que os extensionistas do país necessitam de uma formação especializada de nível superior, que lhes garanta determinadas competências como: organizar, gerir e supervisionar as redes de extensão, o processo de marketing assim como o controle de qualidade dos produtos incorporando neles a adição de valor, realizar e conduzir pesquisas, dados e inquéritos, de entre outros.
Dasar Dan Peran Sistem Informasi Manajemen
Authors: Widodo  , Syafrizal Fuady  
Published: October 2024

Sistem informasi manajemen merupakan hal yang sangat dibutuhkan dalam manajemen. Dan manajemen memiliki peranan yang sangat penting dalam sistem informasi sebagai bahan dalam pengambilan keputusan oleh manajer suatu organisasi. Sistem informasi dalam suatu organisasi dapat dikatakan sebagai suatu sistem yang menyediakan informasi bagi semua tingkatan dalam organisasi tersebut kapan saja diperlukan. Sistem ini menyimpan, mengambil, mengubah, mengolah dan mengkomunikasikan informasi yang diterima dengan menggunakan sistem informasi atau peralatan sistem lainnya. Sistem informasi harus dikembangkan dengan alasan adanya permasalahan berupa adanya ketertinggalan sistem dan pertumbuhan organisasi. Tujuan dari penelitian ini untuk memaparkan konsep dasar sistem informasi manejemen dan bagaimana peranan manajemen dalam sistem informasi.
lingkungan Sosial Pendidikan Di MA Al-Huda Karang Melati Sebagai Pendukung Pembelajaran Bahasa Arab Siswa
Authors: Anang Silahuddin  
Published: October 2024

Guru sebagai satu-satunya sumber belajar adalah paradikma lama yang menjadikan kegiatan belajar mengajar kurang kondusif dan kurangnya inovasi, pengajar di dalam menyampaikan materi dan juga kurangnya para pengajar dalam menguasai materi dan metode menjadikan Susana belajar menjadi terasa sangat membosankan.Tidak terkecuali pelajaran bahasa Arab, pelajaran bahasa Arab adalah pembelajaran yang sangat membutuhkan media untuk membantu peran guru di dalam mengajar, baik media yang berupa audio, atau visual atau bahkan audio visual. Dalam mempelajari bahasa kedua, masuk kedalam dunia bahasa sasaran adalah langkah paling yang paling efektif bagi para pembelajar bahasa.di Nūrus-Sālām misalnya, yang membuat program lingkungan berbahasa untuk membiasakan siswa nya berbahasa Arab.
MageMemo
Authors: Winghart Hunter , Al Zaidy Ahmed 
Published: October 2024

This paper presents MageMemo, an innovative productivity tool that integrates gamification and fantasy storytelling to enhance user engagement in task management. Traditional productivity applications often struggle to sustain long-term user interest, decreasing effectiveness over time. MageMemo addresses this challenge by creating a captivating experience where users earn achievements, level up, and uncover an unfolding narrative as they complete real-life tasks. By combining principles of Human-Computer Interaction (HCI) with a compelling fantasy theme, MageMemo offers a novel approach to improving productivity and motivation. Outlined are the design methodology, technical implementation, and evaluation metrics employed in the development of MageMemo, providing insights into its progression and potential to revolutionize how people use task management applications.
The Path From Litter to Soil: Insights Into Soil C Cycling From Long‐Term Input Manipulation and High‐Resolution Mass Spectrometry
Authors: Reynolds Lorien L. , Lajtha Kate , Bowden Richard D. , Tfaily Malak M. , Johnson Bart R. , Bridgham Scott D. 
Published: April 2018

AbstractThe path of carbon (C) from plant litter to soil organic matter (SOM) is key to understanding how soil C stocks and microbial decomposition will respond to climate change and whether soil C sinks can be enhanced. Long‐term ecosystem‐scale litter manipulations and molecular characterization of SOM provide a unique opportunity to explore these issues. We incubated soils from a 20‐year litter input experiment for 525 days and asked how litter quantity and source (i.e., roots versus aboveground litter) affected C cycling, microbial function, and the size and molecular composition of C pools. Input exclusion led to a 30% loss of soil C, attributable largely to the nonmineral‐associated C fraction, and to declines in soil C decomposition. The absence of roots caused a shift in the microbial catabolic profile, though there was little evidence that root litter was preferentially stabilized. Although C pool size did not change with litter additions, Fourier transform ion cyclotron resonance mass spectrometry analysis of the finest mineral fraction revealed dramatic changes to the chemical composition of carbon. Lipid content increased proportionally with input addition and was subsequently mineralized during incubation, indicating that this fraction was metabolically active. Moreover, nonmetric dimensional scaling showed that both litter treatments and incubation caused the molecular composition of SOM to change. We conclude that the path of C from litter to soil may involve labile pools and root‐driven microbial activity associated directly with SOM in the soil mineral matrix otherwise previously hypothesized to be stable.
Ultrahigh Performance Nanoengineered Graphene–Concrete Composites for Multifunctional Applications
Authors: Dimov Dimitar , Amit Iddo , Gorrie Olivier , Barnes Matthew D. , Townsend Nicola J. , Neves Ana I. S. , Withers Freddie , Russo Saverio , Craciun Monica Felicia 
Published: April 2018

AbstractThere is a constant drive for development of ultrahigh performance multifunctional construction materials by the modern engineering technologies. These materials have to exhibit enhanced durability and mechanical performance, and have to incorporate functionalities that satisfy multiple uses in order to be suitable for future emerging structural applications. There is a wide consensus in the research community that concrete, the most used construction material worldwide, has to be engineered at the nanoscale, where its chemical and physiomechanical properties can be truly enhanced. Here, an innovative multifunctional nanoengineered concrete showing an unprecedented range of enhanced properties when compared to standard concrete, is reported. These include an increase of up to 146% in the compressive and 79.5% in the flexural strength, whilst at the same time an enhanced electrical and thermal performance is found. A surprising decrease in water permeability by nearly 400% compared to normal concrete makes this novel composite material ideally suitable for constructions in areas subject to flooding. The unprecedented gamut of functionalities that are reported in this paper are produced by the addition of water‐stabilized graphene dispersions, an advancement in the emerging field of nanoengineered concrete which can be readily applied in a more sustainable construction industry.
Oxygen Stoichiometry Effect on Polar Properties of LaAlO3/SrTiO3
Authors: Sharma Pankaj , Huang Zhen , Li Mengsha , Li Changjian , Hu Songbai , Lee Hyungwoo , Lee Jung‐Woo , Eom Chang‐Beom , Pennycook Stephen J. , Seidel Jan , Ariando  , Gruverman Alexei 
Published: April 2018

AbstractDiscovery of a ferroelectric‐like behavior of the LaAlO3/SrTiO3 (LAO/STO) interfaces provides an attractive platform for the development of nanoelectronic devices with functionality that can be tuned by electrical or mechanical means. However, further progress in this direction critically depends on deeper understanding of the physicochemical mechanism of this phenomenon. In this report, this problem by testing the electronic properties of the LAO/STO heterostructures with oxygen stoichiometry used as a variable is addressed. Local probe measurements in conjunction with interface electrical characterization allow to establish the field‐driven reversible migration of oxygen vacancies as the origin of the ferroelectric‐like behavior in LAO/STO. In addition, it is shown that oxygen deficiency gives rise to the formation of micrometer‐long atomically sharp boundaries with robust piezoelectricity stemming from a significant strain gradient across the boundary region. These boundaries are not ferroelectric but they can modulate the local electronic characteristics at the interface. The obtained results open a possibility to design and engineer electromechanical functionality in a wide variety of nominally nonpolar and non‐piezoelectric complex oxide heterostructures and thin films.
Drug Repositioning to Alleviate Systemic Inflammatory Response Syndrome Caused by Gram‐Negative Bacterial Outer Membrane Vesicles
Authors: Kim Ji Hyun , Lee Jaewook , Park Kyong‐Su , Hong Sung‐Wook , Gho Yong Song 
Published: April 2018

AbstractSepsis is characterized by systemic inflammatory response syndrome (SIRS) accompanied with infection. Gram‐negative bacteria can evoke sepsis by activating the host immune system, such as the release of IL‐6 and TNF‐α, through their virulence factors. Outer membrane vesicles (OMVs), nanosized bilayered proteolipids derived from Gram‐negative bacteria, harbor various virulence factors and are shown to induce SIRS. Here, drugs are repositioned to alleviate SIRS caused by Gram‐negative bacterial OMVs. Using novel OMV‐based drug screening systems, a total of 178 commercially available drugs are primarily screened, and a total of 18 repositioned drug candidates are found to effectively block IL‐6 and TNF‐α production from OMV‐stimulated macrophages. After excluding the compounds which are previously known to intervene sepsis or which show cytotoxicity to macrophages, the compounds which show dose‐dependency in inhibiting the release of IL‐6 and TNF‐α by the OMV‐stimulated macrophages in vitro and which reduce OMV‐induced SIRS in vivo are selected. Salbutamol, a β2 adrenergic receptor agonist, is selected as a novel candidate to alleviate OMV‐induced SIRS. This study sheds light on using Gram‐negative bacterial OMVs in exploring novel candidate compounds to alleviate inflammatory diseases including sepsis.
Micelle‐Coated, Hierarchically Structured Nanofibers with Dual‐Release Capability for Accelerated Wound Healing and Infection Control
Authors: Albright Victoria , Xu Meng , Palanisamy Anbazhagan , Cheng Jun , Stack Mary , Zhang Beilu , Jayaraman Arul , Sukhishvili Svetlana A. , Wang Hongjun 
Published: April 2018

AbstractTailoring nanofibrous matrices—a material with much promise for wound healing applications—to simultaneously mitigate bacterial colonization and stimulate wound closure of infected wounds is highly desirable. To that end, a dual‐releasing, multiscale system of biodegradable electrospun nanofibers coated with biocompatible micellar nanocarriers is reported. For wound healing, transforming growth factor‐β1 is incorporated into polycaprolactone/collagen (PCL/Coll) nanofibers via electrospinning and the myofibroblastic differentiation of human dermal fibroblasts is locally stimulated. To prevent infection, biocompatible nanocarriers of polypeptide‐based block copolymer micelles are deposited onto the surfaces of PCL/Coll nanofibers using tannic acid as a binding partner. Micelle‐modified fibrous scaffolds are favorable for wound healing, not only supporting the attachment and spreading of fibroblasts comparable to those on noncoated nanofibers, but also significantly enhancing fibroblast migration. Micellar coatings can be loaded with gentamicin or clindamycin and exhibit antibacterial activity as measured by Petrifilm and zone of inhibition assays as well as time‐dependent reduction of cellular counts of Staphylococcus aureus cultures. Moreover, delivery time of antibiotic dosage is tunable through the application of a novel modular approach. Altogether, this system holds great promise as an infection‐mitigating, cell‐stimulating, biodegradable skin graft for wound management and tissue engineering.
Manipulation of Colloidal Particles in Three Dimensions via Microfluid Engineering
Authors: Zhang Bo , Meng Fanshu , Feng Jiangang , Wang Jingxia , Wu Yuchen , Jiang Lei 
Published: April 2018

AbstractThe assembly of nanoparticles into ordered 3D architectures, which requires more complex spatial arrangements of nanoparticles than 2D, is essential to develop new nano‐ or microdevices in the fields of biotechnology, magnetic devices, catalysis, and optoelectronics. However, because of the long‐distance interactions among the nanoparticles or the applied external force, the movement of nanoparticles cannot be precisely controlled, particularly in multidimensional architectures. Therefore, controlling the 3D architecture remains challenging. In this study, the 3D architecture engineering of colloidal particles by manipulating the microfluid morphology is reported, which produces controllable cross‐sections and shapes. The modification of the microfluid morphology, which can be achieved by tuning the physical parameters of the system and the pinning point number, affects the nucleation location, growth rate, and orientation of the architectures. Because of the controllable morphology, the waveguiding distance and direction of 3D architectures can be manipulated. Thus, this study highlights the opportunity for creating morphology‐controlled 3D architectures with potential applications in optoelectronics.
Bioinspired Electrocatalysis of Oxygen Reduction Reaction in Fuel Cells Using Molecular Catalysts
Authors: Zion Noam , Friedman Ariel , Levy Naomi , Elbaz Lior 
Published: April 2018

AbstractOne of the most important chemical reactions for renewable energy technologies such as fuel cells and metal–air batteries today is oxygen reduction. Due to the relatively sluggish reaction kinetics, catalysts are necessary to generate high power output. The most common catalyst for this reaction is platinum, but its scarcity and derived high price have raised the search for abundant nonprecious metal catalysts. Inspired from enzymatic processes which are known to catalyze oxygen reduction reaction efficiently, employing transition metal complexes as their catalytic centers, many are working on the development of bioinspired and biomimetic catalysts of this class. This research news article gives a glimpse of the recent progress on the development of bioinspired molecular catalyst for oxygen reduction, highlighting the importance of the molecular structure of the catalysts, from advancements in porphyrins and phthalocyanines to the most recent work on corroles, and 3D networks such as metal–organic frameworks and polymeric networks, all with nonpyrolyzed, well‐defined molecular catalysts for oxygen reduction reaction.
Development of the Applications of Palladium on Charcoal in Organic Synthesis
Authors: Liu Xiang , Astruc Didier 
Published: April 2018

AbstractPalladium on charcoal (Pd/C) has lots of salient merits: (i) it is a cheap and commercial source of palladium, (ii) it shows efficient catalytic activity even without ligands, (iii) as a heterogeneous catalyst it is easily recycled many times by simple filtration, and (iv) it is applicable to a great number of reactions and substrates, although it is eventually less efficient than homogeneous Pd catalysts containing some sophisticated ligands. This review recalls the main background and summarizes the progress made essentially during the last twelve years in Pd/C‐catalyzed organic synthesis since the reviews by Felpin's group and Seki in 2006.magnified image
Vertically Aligned Lithiophilic CuO Nanosheets on a Cu Collector to Stabilize Lithium Deposition for Lithium Metal Batteries
Authors: Zhang Chen , Lv Wei , Zhou Guangmin , Huang Zhijia , Zhang Yunbo , Lyu Ruiyang , Wu Haoliang , Yun Qinbai , Kang Feiyu , Yang Quan‐Hong 
Published: April 2018

AbstractUncontrollable dendrite growth hinders the direct use of a lithium metal anode in batteries, even though it has the highest energy density of all anode materials. Achieving uniform lithium deposition is the key to solving this problem, but it is hard to be realized on a planar electrode surface. In this study, a thin lithiophilic layer consisting of vertically aligned CuO nanosheets directly grown on a planar Cu current collector is prepared by a simple wet chemical reaction. The lithiophilic nature of the CuO nanosheets reduces the polarization of the electrode, ensuring uniform Li nucleation and continuous smooth Li plating, which is difficult to realize on the normally used lithiophobic Cu current collector surface. The integration of the grown CuO arrays and the Cu current collector guarantees good electron transfer, and moreover, the vertically aligned channels between the CuO nanosheets guarantee fast ion diffusion and reduce the local current density. As a result, a high Columbic efficiency of 94% for 180 cycles at a current density of 1 mA cm−2 and a prolonged lifespan of a symmetrical cell (700 h at 0.5 mA cm−2) can be easily achieved, showing a simple but effective way to realize Li metal‐based anode stabilization.
Mulberry Paper‐Based Supercapacitor Exhibiting High Mechanical and Chemical Toughness for Large‐Scale Energy Storage Applications
Authors: Yun Tae Gwang , Kim Donghyuk , Kim Sang‐Min , Kim Il‐Doo , Hyun Seungmin , Han Seung Min 
Published: April 2018

AbstractIn response to the demand for flexible and sustainable energy storage devices that exhibit high electrochemical performance, a supercapacitor system is fabricated using mulberry tree‐derived paper as a substrate and Poly(3,4‐ethylenedioxythiophene)‐poly(styrenesulfonate) (PEDOT:PSS) and carbon black as the active material. The mulberry paper‐based supercapacitor system demonstrates high energy density of 29.8–39.8 Wh kg−1 and power density of 2.8–13.9 kW kg−1 with 90.7% retention of its initial capacity over 15 000 charge–discharge cycles. In addition, the mulberry tree fibers are known to have superior mechanical strength and toughness and the mulberry paper‐based supercapacitor; as a result, exhibit high mechanical and chemical toughness; 99% of its initial capacity is retained after 100 repeated applications of bending strains, and twisting. 94% capacity retention is observed even after exposure to HCl and H2SO4 acid solutions. The fabrication methodology of the mulberry‐based supercapacitor is highly scalable and could be stacked to increase the energy storage capacity, where operation of light‐emitting diode lights with a drive voltage of 12 V integrated in a wearable device is demonstrated.