bluuebunny/crossref_metadata_2025_split huggingface dataset:
Medienwechsel präzise erkennen
Authors: Faustmann Heiko 
Published: May 2019

AbstractBei der Lebensmittel‐ und Getränkeherstellung gilt es, strenge Qualitäts‐ und Hygienerichtlinien einzuhalten. Deshalb müssen Produktionsanlagen bei Chargen‐ oder Produktwechsel regelmäßig gereinigt werden. Der Produktionsprozess soll gleichzeitig aber möglichst effizient durchgeführt werden. Der Flowave‐Durchflussmesser von Bürkert Fluid Control Systems bietet nun erweiterte Funktionen, mit denen sich unter anderem äußerst schnell und präzise Medienwechsel erkennen lassen. So können Produktionsschritte klar voneinander getrennt und Ausschuss verringert werden, ohne die Hygiene zu beeinträchtigen.
Ausfallsicher und ökonomisch und ökologisch fördern
Authors: van Dorp Annette 
Published: May 2019

AbstractIn der chemischen Industrie sind die Anforderungen an den Pumpeneinsatz besonders hoch. Gerade die Förderung von Säuren, Laugen oder toxischen, korrosiven oder gashaltigen Lösungen stellt hohe Ansprüche an das Pumpensystem. Zusätzlich erschweren hohe Temperaturen oder Feststoffe im Medium den Einsatz. Solche Bedingungen führen in der Praxis regelmäßig zu Schäden, wenn Standardkreiselpumpen die Akteure sind. Bei der Pumpenauswahl sollte eine sichere und störungsfreie Förderung im Vordergrund stehen. Deshalb ist hier die hermetisch dichte Spezialkreiselpumpe MPCHDryRun die erste Wahl.
Genaue Kontrolle
Authors: Schmitz Dirk 
Published: May 2019

AbstractDie neuen Grundfos DID „plug & measure“‐Systeme sind die perfekte Kombination von hochmodernen digitalen Modbus Sensoren für unterschiedlichste Parameter mit einem Auswerte‐ und Regelterminal (CU382) zur Verwendung mit Grundfos Smart Digital Dosierpumpen, Gasdosiersystemen oder In‐situ‐Biozidsystemen.
Auf den Punkt genau
Authors: Kirschbauer Volker 
Published: May 2019

AbstractAufgrund ihrer Eigenschaft, in unterschiedlichen Stoffen löslich zu sein, kommen Emulgatoren häufig zum Einsatz, wenn miteinander nicht mischbare Komponenten vermengt werden sollen. Um eine geeignete Mischung zu erzielen, wird der reine, hochkonzentrierte Emulgator im Vorfeld auf Gebrauchsstärke verdünnt. Mischanlagen zur Herstellung eines Emulgators müssen vor allem eine hohe Dosiergenauigkeit aufweisen. Da der bisherige, manuelle Prozess dies nicht in ausreichendem Maß sicherstellen konnte, wandte sich ein international operierender Chemiekonzern an die Experten von Lewa. Deren Dosieranlagen sind mit Durchflussmessern ausgestattet, die fortlaufend den geforderten Verdünnungsgrad von 20 % überprüfen.
On‐Surface Assembly of Au‐Dicyanoanthracene Coordination Structures on Au(111)
Authors: Yan Linghao , Pohjavirta Ilona , Alldritt Benjamin , Liljeroth Peter 
Published: May 2019

AbstractOn‐surface metal‐organic coordination provides a promising way for synthesizing different two‐dimensional lattice structures that have been predicted to possess exotic electronic properties. Using scanning tunneling microscopy (STM) and spectroscopy (STS), we studied the supramolecular self‐assembly of 9,10‐dicyanoanthracene (DCA) molecules on the Au(111) surface. Close‐packed islands of DCA molecules and Au‐DCA metal‐organic coordination structures coexist on the Au(111) surface. Ordered DCA3Au2 metal‐organic networks have a structure combining a honeycomb lattice of Au atoms with a kagome lattice of DCA molecules. Low‐temperature STS experiments demonstrate the presence of a delocalized electronic state containing contributions from both the gold atom states and the lowest unoccupied molecular orbital of the DCA molecules. These findings are important for the future search of topological phases in metal‐organic networks combining honeycomb and kagome lattices with strong spin‐orbit coupling in heavy metal atoms.
Electrocatalytic Reduction of CO2 to Methanol by Iron Tetradentate Phosphine Complex Through Amidation Strategy
Authors: Bi Jiaojiao , Hou Pengfei , Liu Fang‐Wei , Kang Peng 
Published: May 2019

AbstractThe iron complex of tetradentate tris[2‐(diphenylphosphino) ethyl]phosphine (PP3), [Fe(PP3)(MeCN)2](BF4)2, was able to electrocatalytically reduce CO2 to formate with a Faradaic efficiency (FE) of approximately 97.3 % in acetonitrile. Upon addition of diethylamine as a cocatalyst, electrocatalytic reduction to methanol was achieved with an FE of 68.5 %, and other products were formamide and formate. A mechanistic study suggested that the [FeH(PP3)](BF4) hydride complex was the active species in the electrocatalysis. Added amine as cocatalyst could react with CO2 to form carbamate, which could then be reduced to formamide and further to methanol. By contrast, free CO2 could only be reduced to formate as the end‐product.
Duo triangle‐shaped rectangular microstrip‐fed patch antennas input and output parameters investigation
Authors: Bodo Régine , Mbinack Clément , Eyébé Fouda Jean‐Sire Armand , Tonye Emmanuel 
Published: May 2019

SummaryConventional rectangular microstrip‐fed patch antennas are initially investigated numerically within the frequency band 2.0 to 2.8 GHz for Wi‐Fi applications. In order to enhance the input parameters of the underlying antennas, three prototypes are designed. A split is diagonally loaded on a conventional radiating patch to achieve a duo triangle‐shaped microstrip‐fed patch antenna in the first step. The conducting ground plane of the conventional and the duo triangle‐shaped patches is modified to design the microstrip‐fed monopole and duo triangle‐shaped monopole antennas in the second and third steps, respectively, within the frequency band of 2.0 to 7.0 GHz. Concepts of voltage and current waves as well as classical electrostatics approach solutions are used to, respectively, investigate the return loss bandwidth and the electric field radiation pattern of the proposed antennas. Numerical simulations show some relevant antenna performances such as a triple‐band, a −10‐dB return loss bandwidth of 29%, a gain of 7.5 dB, and a calculated half power beam width of 120° in E‐plane.
Hyaluronic acid induced foreign body reaction mimicking neoplastic parotid cytology
Authors: Davis Adam , Basu Devraj , Suyash Mohan , Jalaly Jalal B. 
Published: May 2019

AbstractMasses near the angle of the mandible containing extracellular matrix or mucin on cytology raise concern for various benign and malignant parotid gland neoplasms. Here a 76‐year‐old female with a history of cosmetic hyaluronic acid (HA) filler injections presented with a painless 6 mm left sided facial mass. Injection of hyaluronidase into the mass had failed to cause regression, raising concern for a neoplastic process. Fine‐needle aspiration (FNA) showed amorphous, mucinous/extracellular matrix‐like material in a background of numerous histiocytes and occasional multinucleated giant cells, consistent with a foreign body giant cell reaction to HA. This uncommon reaction to HA filler creates previously unrecognized diagnostic pitfalls because of its resemblance on FNA to the extracellular matrix or mucin found in many salivary neoplasms.
Capability of polygonum cuspidatum extract in inhibiting AGEs and preventing diabetes
Authors: Sheng Zhanwu , Ai Binling , Zheng Lili , Zheng Xiaoyan , Yang Yang , Shen Yixiao 
Published: May 2019

AbstractDiabetes is a metabolic disorder disease associated with advanced glycation end products (AGEs) and protein glycation. The effect of polygonum cuspidatum extract (PE) on AGEs and Nε‐(Carboxymethyl)‐L‐lysine formation, protein glycation, and diabetes was investigated. Six primary phenolics in a range of 12.36 mg/g for ellagic acid to 0.01 mg/g for piceid were determined in PE. In an intermediate‐moisture‐foods model, inhibition rate of PE was as high as 54.2% for AGEs and 78.9% for CML under aw 0.75. The protein glycation was also inhibited by PE. In a diabetic rat model, the levels of blood glucose, serum malondialdehyde, cholesterol, triglycerides, and low‐density lipoproteins were effectively reduced by PE treatment. The antioxidation capacity (T‐AOC) and superoxide dismutase (SOD) activity were also mediated by PE. Additionally, the activates of liver function‐related enzymes including alkaline phosphatase (ALP), glutamate pyruvate transaminase (GPT), and glutamate oxaloacetate transaminase (GOT) in diabetic rat were improved by PE.
Optimization of deacidification for concentrated grape juice
Authors: Li Ning , Wei Yue , Li Xuemeng , Wang Jiahui , Zhou Jiaqian , Wang Jie 
Published: May 2019

AbstractExcessive organic acids in grape juice will not only result in poor taste but will also cause turbidity and sedimentation. Tartaric acid exerts the most significant acidity among all organic acids in grape juice. In this study, we used tartaric acid as the main target and anion‐exchange resin to remove tartaric acid from concentrated grape juice. Factors influencing the removal process were optimized by liquid chromatography with ultraviolet detection and statistical analysis for optimal deacidification of concentrated grape juice. Use of the anion‐exchange resin 335 treat the concentrated grape juice at a ratio of 1:6 (2:11.98) at 15.57°C for 4.35 hr. The tartaric acid removal rate reached 69.01%; the anion‐exchange resin 335 demonstrated the best removal effect.
Effects of Lactobacillus plantarum CQPC01‐fermented soybean milk on activated carbon‐induced constipation through its antioxidant activity in mice
Authors: Liu Bihui , Xiao Xiao , Zhou Xianrong , Zhou Jie , Lan Lingxia , Long Xingyao , Pan Yanni , Du Muying , Zhao Xin 
Published: May 2019

AbstractA newly found strain, Lactobacillus plantarum CQPC01 (LP‐CQPC01), was used for soybean milk fermentation, and its effects against constipation were determined. LP‐CQPC01‐FSM (LP‐CQPC01‐fermented soybean milk) was found to have six kinds of soybean isoflavones; the isoflavones of LP‐CQPC01‐FSM were more than those of Lactobacillus bulgaricus‐fermented soybean milk (LB‐FSM) and unfermented soybean milk (U‐FSM). Animal experiment showed that the MTL, Gas, ET, AchE, SP, VIP, and GSH levels in the constipated mice were increased; however, the SS, MPO, NO, and MDA levels in the constipated mice were reduced by soybean milk treatment. Further, LP‐CQPC01‐FSM increased the mRNA and protein expression of Cu/Zn‐SOD, Mn‐SOD, CAT, c‐Kit, SCF, and GDNF and reduced the expression of TRPV1 and NOS relative to those of the mice with untreated constipation. LP‐CQPC01 could be used as a new starter to produce high‐quality soybean milk, which might be used as a functional drink.
Treatment of Philadelphia‐negative myeloproliferative neoplasms in accelerated/blastic phase with azacytidine. Clinical results and identification of prognostic factors
Authors: Andriani Alessandro , Elli Elena , Trapè Giulio , Villivà Nicoletta , Fianchi Luana , Di Veroli Ambra , Niscola Pasquale , Centra Antonia , Anaclerico Barbara , Montanaro Guido , Martini Vincenza , Aroldi Andrea , Carmosino Ida , Voso Maria Teresa , Breccia Massimo , Montanaro Marco , Foà Roberto , Latagliata Roberto 
Published: May 2019

AbstractThere have been some reports on a possible role of azacytidine (AZA) in the treatment of accelerated/blastic phase evolved from Philadelphia‐negative myeloproliferative neoplasms (MPN‐AP/BP), but results are conflicting. In this study, we analyzed a cohort of 39 patients with MPN‐AP/BP treated frontline with AZA at the standard dosage (75 mg/m2). Median time from diagnosis to AP/BP evolution was 92.3 months (IR 29.9‐180.1). All patients were evaluable for hematologic response: two patients (5.2%) died early after AZA initiation, 13 patients (33.3%) had a progressive or stable disease, nine (23.1%) had a hematologic improvement (HI), seven (17.9%) achieved a partial response (PR), and eight (20.5%) a complete response (CR). Overall, 24 patients achieved a clinical hematologic response (HI + PR + CR), with an overall response rate of 61.5%. Median overall survival (OS) from AZA start of the whole cohort was 13.5 months (95% CI, 8.2‐18.7). There was no difference in median OS among patients with HI, PR, or CR (P = .908). These three subgroups as “responders” having been considered, a significantly better OS was observed in responder compared with nonresponder patients, with a median OS of 17.6 months (95% CI, 10.1‐25.0) versus 4.1 months (95% CI, 0.4‐10.0) (P = .001) Only female gender was significant for both achievement of response (.010) and OS duration (P = .002). In conclusion, AZA is useful for the management of MPN‐AP/BP, with an overall response rate (HI + PR + CR) of 61.5% and a longer OS in responders.
Chitosan biopolymer‐derived self‐powered triboelectric sensor with optimized performance through molecular surface engineering and data‐driven learning
Authors: Ma Chenxiang , Gao Shengjie , Gao Xinqi , Wu Min , Wang Ruoxing , Wang Yixiu , Tang Zhiyuan , Fan Fengru , Wu Wenxuan , Wan Hong , Wu Wenzhuo 
Published: May 2019

AbstractThe state‐of‐the‐art triboelectric nanogenerators (TENGs) are constructed with synthetic polymers, curtailing their application prospects and relevance in sustainable technologies. The economically viable transformation and engineering of naturally abundant materials into efficient TENGs for mechanical energy harvesting is meaningful not only for fundamental scientific exploration, but also for addressing societal needs. Being an abundant natural biopolymer, chitosan enables exciting opportunity for low‐cost, biodegradable TENG applications. However, the electrical outputs of chitosan‐based TENGs are low compared with the devices built with synthetic polymers. Here, we explore the facile molecular surface engineering in chitosan to significantly boost the performance of chitosan‐based TENG for enabling the practical applications, for example, self‐powered car speed sensor. The molecular surface engineering offers a potentially promising scheme for designing and implementing high‐performance biopolymer‐based TENGs for self‐powered nanosystems in sustainable technologies. We further explore for the first time the feasibility of data mining approaches to analyze and learn the acquired triboelectric signals from the car speed sensors and predict the relationship between the triboelectric signals and car speed values.
Effects of metastasectomy and other factors on survival of patients with ovarian metastases from gastric cancer: a systematic review and meta‐analysis
Authors: Zhang Chao , Hou Wenbin , Huang Jinyu , Yin Songcheng , Wang Pengliang , Zhang Zhe , Tan Yuen , Xu Huimian 
Published: May 2019

AbstractOvarian metastasis from gastric cancer (Krukenberg tumor [KT]) has no consensus treatment and the role of surgical treatment is still controversial. Identifying prognostic factors for KT could help guide the management of this tumor. We used a meta‐analysis to evaluate the prognostic value of metastasectomy and other factors in patients with KT to develop a treatment plan. We searched literature in PubMed, Cochrane library and EMBASE. We analyzed hazard ratios (HR) and 95% confidence intervals (CI) with respect to overall survival (OS). The meta‐analysis included 12 cohort studies with 1,031 patients associated with longer OS following metastasectomy (HR = 0.41; 95% CI = 0.32–0.53; P < 0.001), R0 resection (HR = 0.37; 95% CI = 0.26–0.53; P < 0.001), metachronous ovarian metastasis (HR = 0.74; 95% CI = 0.58–0.93; P = 0.012), size of KT (<5 cm) (HR = 0.74; 95% CI = 0.58–0.95; P = 0.019), ECOG PS (Eastern Cooperative Oncology Group performance status) 0 to 1 (HR = 0.48; 95% CI = 0.29–0.80; P  = 0.004), tumor confined to ovary (HR = 0.40; 95% CI = 0.16–0.99; P  = 0.047), and tumor confined to pelvic cavity (HR = 0.36; 95% CI = 0.14–0.92; P  = 0.033). Shorter OS was associated with peritoneal carcinomatosis (HR = 2.00; 95% CI = 1.25–3.21; P  = 0.004), ascites (HR = 1.66; 95% CI = 1.19–2.31; P  = 0.003) and positive CEA (HR = 1.41; 95% CI = 1.10–1.82; P  = 0.007). Gastrectomy led to a slight improvement in OS, but without statistical significance (HR = 0.69; 95% CI = 0.47–1.02; P  = 0.061). No significant difference in OS was observed in patients with signet‐ring cells (HR = 1.17; 95% CI = 0.91–1.51; P  = 0.226), bilateral ovarian metastasis (HR = 0.87; 95% CI = 0.70–1.08; P  = 0.212), age ≥ 50 years (HR = 0.93; 95% CI = 0.71–1.22; P  = 0.619), positive CA19‐9 (HR = 1.01; 95% CI = 0.75–1.35; P  = 0.960), and positive CA‐125 (HR = 0.98; 95% CI = 0.73–1.33; P  = 0.915). Various factors affect OS in patients with KT.
A seven‐long noncoding RNA signature predicts relapse in patients with early‐stage lung adenocarcinoma
Authors: Zhou Huihui , Zhang Hongwei , Chen Juan , Cao Jiangbo , Liu Lin , Guo Cheng , Huang Ge , Zeng Danli 
Published: May 2019

AbstractBackgroundLong noncoding RNA (lncRNA) has been increasingly reported to play crucial roles in cancer development. In this study, we aim to develop a lncRNA‐based signature to predict the relapse of early‐stage (stage I‐II) lung adenocarcinoma (LUAD).MethodsWith a lncRNA‐mining strategy, lncRNA expression profiles of three LUAD cohorts were obtained from the Gene Expression Omnibus database. A risk score model was established based on the lncRNAs expression from training set (GSE31210, n = 204) and further validated in two independent testing sets (GSE50081, n = 124; and GSE30219, n = 84). The potential signaling pathways modulated by the prognostic lncRNAs were explored using bioinformatics analysis.ResultsIn the training set, seven lncRNAs were identified to be significantly correlated with the relapse‐free survival (RFS) of early‐stage LUAD, and were then aggregated to form a seven‐lncRNA prognostic signature to classify patients into high‐risk and low‐risk groups. Individuals of training set in the high‐risk group exhibited a poorer RFS than those in the low‐risk group (HR: 7.574, 95% CI: 4.165‐13.775; P < 0.001). The similar prognostic powers of the seven‐lncRNA signature were also achieved in the two independent testing sets and in stratified analysis. Multivariate Cox regression indicated that the prognostic value of seven‐lncRNA signature was independent of other clinical features. Functional enrichment analysis found that the seven‐lncRNA signature may be involved in biological pathways such as cell cycle, DNA replication, and p53 signaling pathway.ConclusionOur results indicate that the seven‐lncRNA signature may be an innovative biomarker to predict the relapse of early‐stage LUAD.
Biomass production and nutrients removal from non‐sterile municipal wastewater and cattle farm wastewater inoculated with Chlorococcum sp. GD
Authors: Lv Junping , Wang Xuechun , Feng Jia , Liu Qi , Nan Fangru , Liu Xudong , Xie Shulian 
Published: May 2019

AbstractBACKGROUNDAlthough microalgae had been widely used in wastewater treatment, the treatment efficiency is affected by the carbon limitation of the carbon/nitrogen (C/N) ratio in wastewater. In the present study, the performance on nutrients removal and biomass production was investigated when Chlorococcum sp. GD was inoculated into non‐sterile municipal wastewater and cattle farm wastewater.RESULTSAlthough wastewater had indigenous microalgae and bacteria, microalgae could grow and the growth of indigenous bacteria was inhibited when exogenous Chlorococcum sp. GD was inoculated into non‐sterile municipal wastewater and cattle farm wastewater. Nevertheless, both biomass production and nutrients removal were relatively low due to the low C/N ratio in both wastewaters. When sodium acetate was supplemented to both wastewaters in the late exponential growth stage, biomass production and nutrients removal were enhanced. Moreover, the lipid accumulation from microalgal cells grown in municipal wastewater and cattle farm wastewater were 33.2% and 20.9%, respectively. Linoleic and linolenic acids accounted for 47.64 to 56.41% of the total fatty acids, and were in great demand for dietary supplements and aquacultures.CONCLUSIONChlorococcum sp. GD could be a potential candidate for bioremediation of both wastewaters. The exponential sodium acetate feeding would be an efficient approach for enhancing biomass production and nutrients removal efficiency from wastewater with a low C/N ratio. © 2019 Society of Chemical Industry
Conformational and functional effects of MPA‐CdTe quantum dots on SOD: Evaluating the mechanism of oxidative stress induced by quantum dots in the mouse nephrocytes
Authors: Hao Minglu , Liu Rutao 
Published: May 2019

AbstractThe application of quantum dots (QDs) is restricted by the biosafety issue. QDs contribute to the adverse effects of organisms probably because of the ability to induce oxidative stress via changing the activity of antioxidant enzyme, for example, superoxide dismutase (SOD). But the underlying molecular mechanisms still remain unclear. This study investigated the harmful effects of oxidative stress induced by mercaptopropionic acid capped CdTe QDs (MPA‐CdTe QDs) on the mouse primary nephrocytes as well as the structure and function of SOD molecule and explored the underlying molecular mechanism. After 24‐hour MPA‐CdTe QD exposure, the activation level of extracellular regulated protein kinase (ERK) signaling pathway and cysteinyl‐directed aspartate‐specific proteases (Caspases) significantly increased, which led to the increasing level of reactive oxygen species (ROS) and cell apoptosis; the group pretreated with ROS scavenger N‐acetyl‐L‐cysteine (NAC) significantly reduced the apoptotic cell percentage, indicating that ROS played a critical role in QD‐induced cytotoxicity. Further molecular experiments showed that the interacting processes between the MPA‐CdTe QDs and SOD were spontaneous which changed the conformation, secondary structure of SOD. The interaction significantly resulted in the tightening of polypeptide chains and the shrinkage of SOD, leading to the inhibition of molecular SOD activity. This study demonstrates the adverse effects of QDs, revealing their potential risk in biomedical applications.
Gold organosols for multicomponent surface‐enhanced Raman spectroscopy analysis of paintings
Authors: Kulakovich Olga , Shabunya‐Klyachkovskaya Elena , Trotsiuk Liudmila , Matsukovich Anna , Korza Yauheniya 
Published: May 2019

AbstractThe methods for the synthesis of gold sols in chloroform have been developed. The efficiency of gold organic sol for studying real objects of painting and its advantage over traditional hydrosol was demonstrated. A new practical application of gold organosols is proposed—the use for analysis of paintings by surface‐enhanced Raman scattering that can help to identify the dyes and hydrophobic binders in one probe. In practice, the application of metallic organosols makes possible to substantially simplify the procedure for sample preparation. It was also shown that the intensity of the surface‐enhanced Raman spectroscopy bands and the signal‐to‐noise ratios is improved with organosols in comparison with hydrosol. These results can contribute in the long term to the development of nondestructive approach to the analysis of works of painting.