bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the Government of Liberty
Authors: Kuntz Friederike 
Published: November 2024

Abstract
The liberal script is a product of practice. It is inscribed by numerous devices, whose agency is often ignored. Notably, instructional texts have been prominent intermediators of the liberal script since the 19th century, guiding thinking and conduct. This paper stresses this practical materiality of the liberal script, drawing on Latour and Foucault. Through a study of 19th-century dictionaries, manuals, and textbooks, it illustrates how instructional texts assembled liberalism into a script for government. The exploration highlights the liberal script as an assemblage of entities, subjects, means, forces, ways of doing and seeing human government, and institutions. It also outlines the government of liberty, which forms the core of this script and extends across the state and the international realm. The proposed neo-materialist approach to the liberal script encourages an exploration of this script’s materiality from the 19th to the 21st century and exemplifies instructional techniques across the analyzed texts.
Reallocation
Authors: Schmidt Vivien A. 
Published: November 2024

Abstract
Since the 1980s, the neoliberal allocative script has been highly resilience through successive transformations in the 1990s, the 2000s, and during the financial and Eurozone crises, maintaining its predominance despite contestation from the progressive script. But today the neoliberal script has come under increasing challenge from alternative scripts, first with the regressive populist anti-liberal script serving as a democratic backlash to the impact of neoliberal transformations, then with the COVID-19 crisis response that seemed to put a pause on the neoliberal script, and finally with a more progressive liberal script focused on sustainability. To explain this, we use the analytical framework of discursive institutionalism to consider not only the resilience of the ideas and discourse of the neoliberal script but also the challenges from alternative scripts.
Publicity and Privacy
Authors: Müller Jan-Werner 
Published: November 2024

Abstract
The liberal script has always promised both publicity (as a condition of legitimate government) and privacy (as a right indispensable to autonomous individual self-development). The chapter reconstructs this initially promise and identifies some of the blind spots in the actual history of liberal thought and institutions. It also briefly analyzes a number of structural transformations of the public and the private sphere since the 18th century. It then diagnoses contemporary challenges to the public sphere and to privacy and asks whether these challenges can be met from within the liberal script. In particular, competition and pluralism, individual rights, and transparency are suggested as possible remedies for the problems posed by social media; the limits of these remedies in the face of the novel character of platforms is also acknowledged.
Duty, Motive and Reason
Authors: Strawson P. F. , Dancy Jonathan 
Published: November 2024

Abstract
Lecture 4 discusses reasons as motives, and as always containing desires/emotions. What has morality to say about motives? The rightness of an act must be able to ‘enter into’ the agent’s motive for doing it. And the agent must conceive of ethical goodness as belonging only to things that are possible ends of voluntary actions. So, both goodness-theories and rightness-theories must make some assumptions about motives/desires. Strawson asks: what are the minimal assumptions about motives that are required of any ethical theory?
The Dualism in Motive
Authors: Strawson P. F. , Dancy Jonathan 
Published: November 2024

Abstract
Lecture 7 looks for a theory with the same structure as Kant’s but different elements: two opposed motives. Morality is founded on the recognition of other selves whose ends we make ours. Our motivation is Caritas – love in the widest sense. Strawson discusses the conflict between Caritas and the egocentric motives.
Duties and Goods and ‘Rightness’
Authors: Strawson P. F. , Dancy Jonathan 
Published: November 2024

Abstract
Lecture 10 asks: do our actual moral convictions match the account of the origin of moral thought developed in the previous lectures? Strawson addresses concepts of the disinterested motive; the duties of one’s station; veracity; and the origin of conflicts of duty. Can there be a duty to oneself? Strawson argues not. Duties are addressed to humanity at large – making the ends of others one’s own ends. Similar questions arise about the good: do our convictions about value match the account? We see things as good because we feel we ought to pursue them. Strawson proposes that this solves the problem about the relation between value and duty. He distinguishes two senses of ‘good’: (1), a fundamental sense, in which the good is what we ought to strive for; (2) what I would feel obliged to strive for in a certain kind of situation. Other uses of ‘good’ as in, for example, ‘good action’ may be distinguished. Strawson ends by discussing Broad’s distinction between the materially right, the formally right, and the subjectively right.
The International Political Economy of the Right to Food, 1960–2019
Authors: Fakhri Michael 
Published: November 2024

Abstract
This chapter situates the right to food within the history of food sovereignty movements and their engagement with the Food and Agricultural Organization and World Trade Organization, and the broader history of international trade law. This includes examining the dynamic between social movement and international institutions and the distribution of power and wealth generated by the institutions, practices, legal rules, and social organizations surrounding (or laying claim to) the right to food. This history relates to studies of food regimes, where a food regime is the set of explicit and implicit rules governing the production and consumption of food on a world scale. The chapter provides an example of how a legal analysis of food regimes analytically opens up an understanding of international institutions as sites of struggle within themselves where power and meaning are negotiated and mediated.
From Moynihan to Piketty
Authors: Wolfinger Nicholas H. , McKeever Matthew 
Published: November 2024

Abstract
Much research in recent years has documented the soaring level of income inequality in America. Although many people have speculated on how the growth in mother-headed families has contributed to inequality, there’s relatively little research comparing inequality between mothers, and almost no scholarship on inequality within the population of single mothers. The results presented here show that income inequality has grown even faster for never-married mothers than for married and, especially, divorced mothers. Over the past three decades, a popular discourse has emerged surrounding “Murphy Brown mothers,” successful professional women who choose to have a child on their own. We show that this discourse is largely nonsense: there are very few prosperous never-married mothers. Instead, inequality among this population has grown because more never-married mothers are faring worse in recent years.
Thirty-Nine Years in the Lives of Mothers
Authors: Wolfinger Nicholas H. , McKeever Matthew 
Published: November 2024

Abstract
In this chapter, the authors turn to data from the National Longitudinal Survey of Youth’s (NLSY) 1979 cohort, a panel data set whose respondents have been re-interviewed annually or biennially. These data allow the reader to follow a sample of several thousand young women for almost 40 years to explore the long-term consequences of single motherhood. The survey also allows us to see what these women were like before they became mothers. Chapter 5 is comparable to Chapter 2 in that the authors focus on changing attributes over the study period. The results are clear: women who become single mothers, even if they subsequently get married, have much lower incomes for decades compared to continuously married women. Single mothers, especially women who give birth out of wedlock, are disadvantaged in many other ways—and this is often observable long before women first become mothers. In particular, never-married mothers are likely to hail from less privileged families.
Attitudes toward Your Research and Your Collaborators
Authors: Vidair Hilary B. , Gustafson Pam L. , Feindler Eva L. 
Published: November 2024

Abstract
Chapter 6 focuses on maintaining positive attitudes toward research and collaborators when conducting a research or scholarly project (e.g., a dissertation or thesis) in an applied graduate program in psychology, mental health, or education. First, the chapter reviews the importance of staying current in the literature and being skeptical about outcomes, open-minded, and aware of biases. Second, attitudes toward research-informed practice, particularly the local clinical scientist model, are discussed. Third, the chapter describes ways students can remain positive about working on a research team and balance multiple roles. It then discusses being committed to making midcourse corrections on a project. Finally, students are encouraged to revisit the stages of change and related processes that can help. An accompanying table is designed to help procrastinating students find potential solutions. Another table helps students generate more positive attitudes about receiving feedback.
Skills for Finalizing Your Final Project
Authors: Vidair Hilary B. , Gustafson Pam L. , Feindler Eva L. 
Published: November 2024

Abstract
Chapter 8 focuses on the skills students in applied graduate programs in psychology, mental health, and education need to successfully finalize a research or scholarly project (e.g., a dissertation or thesis). It begins with ways to continue writing a final project once it has been conducted. The chapter then describes how to analyze data and write the results and discussion sections. A worksheet is provided to help students prepare these sections and track their progress. Skills for successfully working with a chair at this stage are described, as well as how to share results with professionals in an applied setting. A table to help with keeping a project’s timeline on track is included. Steps for finalizing a full draft are reviewed. The chapter reviews preparation for the defense meeting and includes a table to evaluate defense readiness. Suggestions for remediation are provided. The chapter concludes with practical strategies for presenting and publishing.
Face-to-face or face-to-screen: A quantitative comparison of conferences modalities
Authors: Zajdela Emma R , Huynh Kimberly , Feig Andrew L , Wiener Richard J , Abrams Daniel M 
Published: November 2024

Abstract
The COVID-19 pandemic forced a societal shift from in-person to virtual activities, including scientific conferences. As society navigates a “new normal,” the question arises as to the advantages and disadvantages of these alternative modalities. We introduce two new comprehensive datasets enabling direct comparison between virtual and in-person conferences: the first, from a series of nine small conferences, encompasses over 12,000 pairs of potential scientific collaborators across five virtual and four in-person meetings on a range of scientific topics; the expressed goal of these conferences is to create novel collaborations. The second dataset, from a series of three large physics conferences, encompasses &gt;250,000 possible pairs of scientific collaborators. Our study provides quantitative insight into benefits and drawbacks of virtual and in-person conferences for team formation, community building, and engagement. We demonstrate the causal role of formal interaction on team formation across both modalities. Our findings show that formal interaction impacted team formation significantly more in virtual settings, while informal interaction played a larger role at in-person conferences as compared with virtual. We show that a nonlinear memory model for predicting team formation based on interaction outperforms seven alternative models. The model suggests that prior knowledge and interaction time contribute to catalyzing collaborations in both settings. Our results underscore the critical responsibility of organizers for optimizing professional interactions, whether virtual or in-person.
Roles of the lamin A-specific tail region in the localization to sites of nuclear envelope rupture
Authors: Kono Yohei , Pack Chan-Gi , Ichikawa Takehiko , Komatsubara Arata , Adam Stephen A , Miyazawa Keisuke , Rolas Loïc , Nourshargh Sussan , Medalia Ohad , Goldman Robert D , Fukuma Takeshi , Kimura Hiroshi , Shimi Takeshi 
Published: November 2024

Abstract
The nuclear lamina (NL) lines the nuclear envelope (NE) to maintain nuclear structure in metazoan cells. The major NL components, the nuclear lamins contribute to the protection against NE rupture induced by mechanical stress. Lamin A (LA) and a short form of the splicing variant lamin C (LC) are diffused from the nucleoplasm to sites of NE rupture in immortalized mouse embryonic fibroblasts (MEFs). LA localization to the rupture sites is significantly slow and weak compared with LC, but the underlying mechanism remains unknown. In this study, wild-type (WT), Hutchinson–Gilford Progeria syndrome (HGPS) knock-in MEFs expressing progerin (PG, an LA mutant lacking the second proteolytic cleavage site), and LA/C-knockout MEFs transiently and heterogeneously expressing LA/C WTs and mutants fused to mEmerald are examined before and after NE rupture induced by single-cell compression and laser microirradiation. The farnesylation at the CaaX motif of unprocessed LA and the inhibition of the second proteolytic cleavage decrease the nucleoplasmic pool and slow the localization to the rupture sites in a long-time window (60–70 min) after the induction of NE rupture. Our data could explain the defective repair of NE rupture in HGPS through the farnesylation at the CaaX motif of unprocessed progerin. In addition, unique segments in LA-specific tail region cooperate with each other to inhibit the rapid accumulation within a short-time window (3 min) that is also observed with LC.
Homologous-adhering/targeting cell membrane- and cell-mediated delivery systems: a cancer-catch-cancer strategy in cancer therapy
Authors: Liu Chenguang , Gao Jingjie , Cheng Yuying , Zhang Shanshan , Fu Caiyun 
Published: November 2024

Abstract
Low tumor enrichment remains a serious and urgent problem for drug delivery in cancer therapy. Accurate targeting of tumor sites is still a critical aim in cancer therapy. Though there have been a variety of delivery strategies to improve the tumor targeting and enrichment, biological barriers still cause most delivered guests to fail or be excreted before they work. Recently, cell membrane-based systems have attracted a huge amount of attention due to their advantages such as easy access, good biocompatibility and immune escape, which contribute to their biomimetic structures and specific surface proteins. Furthermore, cancer cell membrane-based delivery systems are referred to as homologous-targeting function in which they exhibit significantly high adhesion and internalization to homologous-type tumor sites or cells even though the exact mechanism is not entirely revealed. Here, we summarize the sources and characterizations of cancer cell membrane systems, including reconstructed single or hybrid membrane-based nano-/microcarriers, as well as engineered cancer cells. Additionally, advanced applications of these cancer cell membrane systems in cancer therapy are categorized and summarized according to the components of membranes. The potential factors related to homologous targeting of cancer cell membrane-based systems are also discussed. By discussing the applications, challenges and opportunities, we expect the cancer cell membrane-based homologous-targeting systems to have a far-reaching development in preclinic or clinics.
Clearing clouds of uncertainty—a principled approach to determining what qualifies as an ‘accident’ under the Montreal Convention
Authors: Mohamed Hassan 
Published: November 2024

Abstract
The revival of international air travel in the wake of the receding COVID-19 pandemic has refocused the spotlight on the inherent hazards of carriage by air. From a legal perspective, the focal issue is whether any of those air travel-related incidents that may result in passenger death or bodily injury are compensable accidents. This article examines the meaning and scope of the term ‘accident’ under Article 17(1) of the 1999 Montreal Convention (MC99)—the exclusive regime for air carrier liability within international air transportation. The term ‘accident’ is a condition precedent to air carrier liability but has been left undefined by the drafters of MC99, leaving it to national courts to interpret its meaning. Accordingly, the article utilizes a doctrinal and normative methodology to review a select body of case law drawn primarily from common law jurisdictions. It proceeds to identify a set of ten principles that would guide future courts to ascertain whether an alleged event qualifies as an ‘accident’ consistently and predictably. The article also discusses the controversial interpretation of ‘accident’ by the Court of Justice of the European Union, signaling judicial discord, and sheds light on the consequent implications, especially in regard to MC99’s pursuit of global uniformity and achieving a fair balance of interests between passengers and air carriers.
Introgression and Mapping of a Novel Bacterial Blight Resistance Gene xa49(t) from Oryza rufipogon acc. CR100098A into O. sativa
Authors: Bhatia Sukhpreet Kaur , Vikal Yogesh , Kaur Pavneet , Dhillon Gurmanpuneet Singh , Kaur Gurwinder , Neelam Kumari , Malik Palvi , Lore Jagjeet Singh , Khanna Renu , Singh Kuldeep 
Published: November 2024

Bacterial blight (BB) caused by Xanthomonas oryzae pv. oryzae is one of the epidemic diseases in rice. Rapid changes in the pathogenicity of the X. oryzae pv. oryzae pathogen demand the identification and characterization of novel BB resistance genes. Here, we report the transfer and mapping of a new BB resistance gene from Oryza rufipogon acc. CR100098A. Inheritance studies on the BC2F2 population, BC2F3 progenies, and backcross-derived recombinant inbred lines derived from a cross between Pusa44/ O. rufipogon acc. CR100098A//2*PR114 showed that a single recessive gene confers resistance in O. rufipogon acc. CR100098A. Bulked segregant analysis using 203 simple sequence repeat (SSR) markers localized the BB resistance gene on chromosome 11 bracketed between two SSR markers, RM27235 and RM2136. Using PR114 and O. rufipogon acc. CR100098A genotyping by sequencing data, 86 KASP markers within the bracketed region were designed and tested for bulked segregant analysis. Only five KASP markers showed polymorphism between parents, and three were associated with the target gene. Seventy-seven new SSR markers were designed from the same interval. A total of 33 polymorphic markers were analyzed on the whole population and mapped the BB gene in an interval of 2.8 cM flanked by SSR markers PAU11_65 and PAU11_44 within a physical distance of 376.3 kb. The BB resistance gene mapped in this study is putatively new and designated as xa49(t). Fourteen putative candidate genes were identified within the xa49(t) region having a role in biotic stress resistance. The linked markers to the xa49(t) gene were validated in other rice cultivars for its successful deployment in BB resistance breeding.
Impacts of circadian disruptions on behavioral rhythms in mice
Authors: Ma Changxiao , Shen Bingyi , Chen Lihong , Yang Guangrui 
Published: November 2024

AbstractCircadian rhythms are fundamental biological processes that recur approximately every 24 h, with the sleep–wake cycle or circadian behavior being a well‐known example. In the field of chronobiology, mice serve as valuable model animals for studying mammalian circadian rhythms due to their genetic similarity to humans and the availability of various genetic tools for manipulation. Monitoring locomotor activity in mice provides valuable insights into the impact of various conditions or disturbances on circadian behavior. In this review, we summarized the effects of disturbance of biological rhythms on circadian behavior in mice. External factors, especially light exert a significant impact on circadian behavior. Additionally, feeding timing, food composition, ambient temperature, and physical exercise contribute to variations in the behavior of the mouse. Internal factors, including gender, age, genetic background, and clock gene mutation or deletion, are effective as well. Understanding the effects of circadian disturbances on murine behavior is essential for gaining insights into the underlying mechanisms of circadian regulation and developing potential therapeutic interventions for circadian‐related disorders in humans.
The roles of mTORC1 in parathyroid gland function in chronic kidney disease‐induced secondary hyperparathyroidism: Evidence from male genetic mouse models and clinical data
Authors: Khalaily Nareman , Hassan Alia , Khream Yasmeen , Naveh‐Many Tally , Ben‐Dov Iddo Z. 
Published: November 2024

AbstractSecondary hyperparathyroidism (SHP) associated with chronic kidney disease (CKD) contributes to morbidity and mortality, yet the related parathyroid signaling pathways are not fully understood. Previous studies have indicated that the parathyroid mTORC1 pathway is activated in both experimental CKD and hypocalcemia‐induced SHP. Furthermore, mice with parathyroid‐specific mTOR deficiency (PT‐mTOR−/−) exhibit disrupted parathyroid glands, but maintain normal serum PTH levels. Conversely, PT‐Tsc1−/− mice, with mTORC1 hyperactivation, have enlarged glands and high serum PTH and calcium levels. We now uncover links between mTORC1 function, parathyroid gland morphology, and the response to CKD. Despite impaired gland structure, PT‐mTOR−/− mice increased serum PTH to levels similar to controls in response to CKD, but not to acute kidney injury (AKI), highlighting the adaptability of their parathyroid glands to chronic but not acute stimulation. PT‐Tsc1−/− mice, with enlarged glands also exhibited a CKD‐induced rise in serum PTH comparable to controls, but with a reduced magnitude, suggesting compromised secretion capacity. Parathyroid glands from PT‐Tsc1−/− mice displayed sustained high PTH secretion in culture, with no further increase when exposed to calcium‐depleted media, unlike control glands. Complementing these findings, human data from 106 healthcare organizations demonstrated that drug‐induced mTORC1 inhibition is associated with reduced serum PTH and a lower incidence of SHP in kidney transplant recipients. Collectively, our findings underscore the complex interplay between mTORC1 signaling and gland structure in the pathogenesis of SHP.
Stigma and lack of access to quality healthcare in the transgender population
Authors: Kelton Kara 
Published: November 2024

ABSTRACT
More than 1.6 million US adults identify as transgender (that is, a gender different than the one traditionally associated with the biologic sex assigned to them at birth). These patients suffer from healthcare inequity and lack of access to healthcare, causing a public health crisis. This article seeks to raise awareness of this issue and encourage clinicians and healthcare systems to make meaningful changes to reduce healthcare stigma for transgender patients.