bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self-rated health in preadolescents as a predictor for prescription redemption and hospital contacts
Authors: Renneberg C K , Rask C U , Rytter D , Hansen S N , Bech B H 
Published: October 2024

Abstract

Background
The decline in self-rated health among children and adolescents raises concerns for their overall well-being and future health outcomes. We examined whether self-rated health in preadolescence predicts both psychiatric and somatic prescription redemption and hospital contacts in later adolescence.

Methods
This cohort study is part of the Danish National Birth Cohort and focuses on children born between 1996 and 2003. A survey was distributed to 96,382 preadolescents aged 11, who were then followed from 2010 to 2018 (average follow-up of 6.9 years). Data on prescriptions and hospital contacts were obtained from Danish registries. Negative binomial regression was employed to calculate the incidence rate ratio (IRR), comparing preadolescent children who rated their health as poor (‘Not So Good’/’Poor’) to those who rated it as good (‘Excellent’/’Good’).

Results
Of the 47,365 (49.1%) 11-year-old preadolescents who participated in this study, 5.3% reported experiencing poor self-rated health. Overall, adjusted analyses revealed higher rates of prescription redemptions (IRR 1.63 [95% CI: 1.53; 1.73]) and hospital contacts (IRR 1.86 [95% CI: 1.74; 1.99]) in these children. Poor self-rated health in preadolescence was associated with more somatic (IRR 1.51 [95% CI: 1.40; 1.62]) and psychiatric (IRR 3.04 [95% CI: 2.59; 3.57]) prescriptions, as well as somatic (IRR 1.61 [95% CI: 1.51; 1.72]) and psychiatric (IRR 2.80 [95% CI: 2.42; 3.25]) hospital contacts in adolescence, with similar associations across sexes.

Conclusions
Poor self-rated health in preadolescence is associated with higher rates of prescription redemption and hospital visits in adolescence, suggesting that perceptions of health in early life influence long-term well-being, especially regarding psychiatric health. This straightforward self-rated health measure offers healthcare professionals valuable insights for identifying children who may require support and early intervention.

Key messages
• Poor self-rated health in preadolescence predicts higher prescription redemption and hospital visits in adolescence, especially regarding psychiatric health.
• Simple self-assessment of health in childhood may have the potential to help identify those needing support and early intervention for long-term well-being.
Social and environmental determinants of sleep health disparities
Authors: Johnson Dayna 
Published: October 2024

Abstract
Sleep is not equitable. Historically minoritized individuals have a high prevalence of sleep disorders and adverse sleep health. Research supports that social determinants of health are contributing to sleep health inequities. Further, sleep is socially patterned. Neighborhoods with high rates of crime, violence, disadvantage, pollution, inopportune light exposure, and noise, where historically minoritized individuals are most likely to live are associated with adverse sleep health and sleep disorders. Social determinants including discrimination, racism, socioeconomic status, lack of access to care are associated with adverse sleep health, particularly among minoritized individuals. While there is an abundance of evidence identifying risk factors for adverse sleep health, evidence also supports factors that promote healthy sleep. A small but growing literature supports that neighborhood social environment is associated with healthy sleep and may be avenue for addressing sleep disparities. Dr. Johnson will present epidemiologic data on the social and environmental determinants of adverse sleep health using a socioecological framework and discuss the mechanisms by which these factors are contributing to sleep disparities. The goal is to identify these factors, and how they can be utilized to address sleep health disparities.
Strategies to address common sleep disorders among middle-aged and older adults
Authors: Kendzerska Tetyana 
Published: October 2024

Abstract
Obstructive sleep apnea (OSA) is an underdiagnosed and prevalent condition in middle-aged and older adults, with a disproportionate burden of OSA in marginalized populations. Lack of appropriate and timely treatment puts many at risk of poor quality of life, comorbidity, motor vehicle crashes and increased health care utilization. Furthermore, social and environmental disparities were acknowledged as contributing to sleep health disparities, OSA health literacy and adherence to OSA treatment. This presentation will overview the social and environmental determinants of OSA prevalence and management. The presenter will also cover strategies to improve access and waiting time for OSA diagnosis and treatment in middle-aged and older adults, such as screening for OSA in general and marginalized populations, alternative at-home OSA detection solutions, involvement of alternative care providers in OSA care, alternative OSA targeted therapies, including accessible self-administered interventions, health equity interventions targeting OSA, and promotion of sleep-centered lifestyle approaches, including weight loss, diet and exercise.
Socioeconomic drivers of low value screening
Authors: Smit Frerik 
Published: October 2024

Abstract
Low-value care brings minimal or no benefit to the patient and is a growing concern for healthcare systems. In this presentation, we will discuss the issue of low-value cancer screening, its frequency, and how it is socially patterned. The general population, policymakers, and healthcare providers expect a lot from cancer screening, while the actual absolute benefits are generally relatively low. In addition, screening practice often does not follow recommendations regarding the frequency of testing or the ages at which to start and to stop, and many screenings providing no benefit are commonly performed. Addressing low-value screening is key for evidence-based population health management and prevention.
2.Y.2. International Health Regulations – role on disease control and global challenges
Authors:   Organised by: Universidade Nova de Lisboa (Portugal), WHO Collaborating Center for Health Workforce Policies and Planning,   Chair persons: Rita Sá Machado (Portugal), Carina Silva (Portugal)
Published: October 2024

Abstract

The International Health Regulations (IHR) are a legal instrument aimed to control infectious disease epidemics worldwide and that makes countries accountable for monitoring and promptly notifying the World Health Organization (WHO) of events that are likely to represent a public health emergency. The 196 signatory countries are bound by this international agreement. This workshop aims to present evidence on the role and updates of the IHR as a framework for global health preparedness. It will do that by exploring the main components of the IHR and their practical implications for public health practice, with particular emphasis on their function in preventing, detecting, and responding to cross-border public health threats. The workshop will feature four short presentations, in a total of 15 minutes, beginning with three presentations showcasing the findings of literature reviews covering various aspects of the IHR. These topics include the main challenges to implementation, the effectiveness of the IHR during the COVID-19 pandemic, its relevance to travel medicine and zoonosis prevention, and strategies for controlling vector-borne diseases. The last presentation will delve into the challenges and opportunities associated with implementing the IHR at both national and international levels, in the context of the proposals from the Working Group on Amendments to the International Health Regulations (2005). Throughout the workshop, emphasis will be placed on understanding how the IHR facilitate collaboration and coordination among countries during health emergencies, as well as the importance of capacity-building, information sharing, and multisectoral collaboration. This structure will allow for discussion aimed at areas for improvement to the IHR, especially in the context of its revision process and global health governance. We believe the added value of this workshop will be creating a platform for critical analysis and dialogue, sharing insights into the evolution of the IHR, ongoing debates, controversies, and emerging trends in global health regulations.

Key messages
• This workshop provides a platform for in-depth exploration of the IHR’s role in global health preparedness, offering evidence on its components and practical implications.
• Through analysis of challenges and discussions on disease control, attendees will engage in critical dialogue aimed at improving the IHR and enhancing global health governance.
International Health Regulations’ role in zoonosis prevention, and intersection with travel medicine
Authors: Martinho J , Diogo E , Mateus R , Fernandes S , Carvalho T , Dionísio J , Santos M A , Castro Silva C , Melo Ferreira V , Cardoso M 
Published: October 2024

Abstract
Trade interferes with the number and frequency of new species introduced and the possibility of these remaining and dispersing, impacting disease transmission dynamics. The International Health Regulations (IHR) establish the need to ensure veterinary care for animals affected by infectious diseases that pose a risk to public health through isolation, treatment and the demanding of other services. Concurrently, globalisation and increased travel have reshaped disease epidemiology, and new and old pathogens threaten to up-end the balance of travel. Two scoping reviews were conducted to explore the IHR’s role in animal monitoring and control and its interface with travel medicine. The scoping reviews followed Joanna Briggs Institute (JBI) framework, utilising the PubMed, B-on, Biomedcentral, ScienceDirect, Medscape, Medline, World of Science, SCOPUS, and Google Scholar databases. English publications and grey literature were included. Regarding animal control, 21 articles were analysed. Most focused-on zoonosis prevention and addressed the international context and highlighted the international significance of applying the IHR for animal monitoring and control, addressing all core capacities. As for travel medicine, other 21 articles were included, highlighting applications in vaccine management, notably for COVID-19 and yellow fever. The IHR and its core capacities are essential in the monitoring and control of animals, with the One Health approach and effort sharing being the ideal method to prevent and respond to outbreaks and pandemics of zoonotic diseases. On the other hand, there is sparse literature about the integration of travel medicine within the IHR framework. Lack of standardisation in methods to evaluate the impact of the IHR is an issue. There’s a need for closer collaboration between clinical practice and legal frameworks to enhance global health preparedness.
3.X.2. Integrating trust as a key component of pandemic preparedness and resilience
Authors:   Organised by: WHO,   Chair persons: Brian Yau (Switzerland), Sandra Machiri (Switzerland)
Published: October 2024

Abstract

Trust is a key component of pandemic preparedness, which impacts the success of response measures during the public health emergency. Trust is built during preparedness, however the drivers and dimensions of trust are complex and context-specific. What is required is a collaborative, inclusive approach that provides a platform for communities to express their questions and concerns. The proposed workshop will begin with a presentation from a global expert on trust in the content of epidemics and pandemics and the current knowledge about how trust can be built during preparedness. This will be followed by interactive group-work, designed to encourage collaborative discussions and decision-making. Finally, introducing the WHO Hive digital platform that provides a safe space for public health communities to share information and ask questions. Attendees will then reconvene in plenary to discuss these approaches and interventions that can be implemented to build and maintain trust prior to and during an epidemic or pandemic.
This workshop has the following objectives:

1. To demonstrate how trust is an important determinant of successful pandemic response; 2. To enable attendees to explore how the implementation of public health and social measures, infodemic management and digital community partnerships and engagement can build trust during pandemic preparedness for both online and offline communities; 3. To provide opportunity for attendees to workshop how the different features of the Hive digital space can enhance trust building, and to develop actionable strategies for health emergency preparedness, response and resilience.
The workshop will deliver these objectives through an interactive simulation activity. Attendees will be placed into small groups to work through a scenario, having to decide on the actions that need to be taken, considering budget constraints, other health priorities, and the current local context. The teams will co-create actionable strategies for building and maintaining trust. While there is not a one size fits all approach to trust building, this workshop will aim to increase understanding of the drivers and determinants of trust to encourage participants to consider how they can be applied in their local context. It will be interactive and hands-on requiring active participation from participants.

Key messages
• Trust as a construct is an important component of pandemic preparedness and readiness that impacts on response.
• A multidimensional approach to building and sustaining trust needs to considered across a range of drivers and determinants, where actionable strategies are vital.
The state-of-the-art and barriers for the adoption of personalised prevention in Europe and beyond
Authors: Boccia S , Farina S , Osti T , Russo L , Maio A , Scarsi N , Savoia C , Taha A , Pastorino R 
Published: October 2024

Abstract
Personalized prevention is a priority of the European Commission’s research agenda, exemplified by the EU-funded project ‘a PeRsonalised Prevention roadmap for the future HEalThcare’ (PROPHET), a coordination and support action of the International Consortium for Personalized Medicine. It aims to bolster health systems in implementing innovative, sustainable, and high-quality personalized strategies to prevent chronic diseases. In this context, a scoping review was conducted to map personalized preventive approaches (PPA) for chronic diseases and obstacles to their adoption worldwide. The review followed the Arksey-O’Malley guidelines and was conducted from January 2017 to December 2023, on PubMed, Web of Science, Scopus, and grey literature. Eligible studies were primary reports and guidelines, while for the barriers to their adoption we included literature reviews. We included 120 documents on approaches and 34 reviews on barriers. Among the former, 251 PPA were identified: 69% on cancer, 21% on cardiovascular diseases, and 10% on neurological, psychiatric, and metabolic diseases. Furthermore, 27% were on primary prevention, using omic biomarkers to predict disease risk and guide preventive strategies; 27% on secondary prevention, using genomics to guide screening programs; 46% on tertiary prevention, using pharmacogenomics or targeted therapies to prevent disease complications. Among the 34 reviews on barriers, the majority were about the lack of clinical utility evidence and research needs, ethical and legal issues, and limited knowledge among health professionals, citizens, and patients. The majority of the barriers (76%) were referred to primary and secondary prevention, consistent with the low rates of existing approaches in these areas. Ongoing efforts show promise for tailoring prevention strategies, but further research and integration are needed to maximize their potential in improving population health and reducing chronic disease burdens on health systems.
The 1+Million Genomes Maturity Level Model for Genomics in Healthcare
Authors: Vicente A 
Published: October 2024

Abstract
The 1+Million Genomes Initiative (1+MG) has been fostering reflection in European countries on their national strategies for genomic medicine, and how these can contribute to research development and improved medical practice. For all citizens to truly benefit from genomic medicine, there must be equitable access across Europe. However, European countries are currently at different stages of implementation of genomics in medical practice. To bridge these gaps, health decision-makers need to understand the maturity of genomic medicine practices in their healthcare systems, to make informed decisions about investment, resources, and practices towards optimized adoption of genomics in healthcare systems. This presentation will focus on the 1+MG Maturity Level Model (MLM), developed in the context of the 1+MG Initiative and B1MG project. This MLM was created as a tool for countries to self-assess the maturity of genomic medicine practices in their healthcare systems, and to define a path to optimization. The MLM content was validated through a Delphi survey with international genomics and public health experts, and a pilot in real-life settings was conducted in eight European countries. The 1+MG MLM pilot provided valuable insights regarding common strengths, weaknesses, and asymmetries across Europe, highlighting the need for national and cross-European investments to close existing gaps, and make personalised medicine accessible to all citizens and patients in Europe.
Benefits of cross-border access to human genomes at scale for research and healthcare
Authors: Scollen S 
Published: October 2024

Abstract
Genomics data will soon be routinely generated and integrated into national healthcare systems. To maximise the potential of genomic medicine, data should be accessible for research where possible. This is the remit of ELIXIR, an intergovernmental organisation that brings together life science resources from across Europe. Innovative solutions are needed to ensure the validated research findings for disease or preventative medicine are then integrated into healthcare. To tackle this, the 1+MG initiative, a joint initiative of 25 EU countries, the UK, and Norway, aims to enable secure access to genomics and the corresponding clinical data across Europe for better research, personalised healthcare and health policy making. In the design and scale-up phase (B1MG project), recommendations and guidelines to advance towards the deployment of personalised medicine at a European scale have been produced, adopted by 1+MG and developed into a 1+MG framework. This includes guidance on data governance, standards, quality and infrastructure, recommendations on how to approach citizen engagement and a tool for countries to self-assess implementation into healthcare. The European Genomic Data Infrastructure (GDI) project supports the scale-up and sustainability phase of the 1+MG initiative, to deploy infrastructure across 24 countries to support the overall ambition. Recommendations are being used to promote governance and technical interoperability across European initiatives including the European Health Data Space (EHDS), and European Cancer Image Initiative (EUCAIM). The 1+MG will be established as a European Data Infrastructure Consortia in 2025 and will act as an Authorised Participant in the EHDS providing access to a permanent high-quality federated data collection of genomic and health data that will accelerate research, innovation and policymaking facilitating the deployment of genomic medicine across Europe.
Addressing vulnerable groups in (public) health and humanitarian crises using RCCE-IM strategies
Authors: Aslan D 
Published: October 2024

Abstract

Background
Vulnerable groups, including older people, infants and children, women, people with disabilities, migrant populations, individuals with marginalized sexual and gender identities, etc., become more fragile in public health and humanitarian crises. These groups’ vulnerability limits their access to health care and other services. Labeling, stigmatization, stereotyping, and other negative consequences contribute to the burden. Concurrent with the motto of the World Health Organization, “Leaving no one behind,’ it reminds us of the need for equality and equity-based models to reach these vulnerable groups in such crises.

Methods
Existing scientific literature and perspectives were synthesized.

Results
Novel Coronavirus Disease (COVID-19) contains various experiences. Since the pandemic, the need for interdisciplinary approaches and strategies has become more apparent based on the complexity and intersectionality of the determinants of the crisis. In this regard, Risk Communication (RC), Community Engagement (CE) and Infodemic Management (IM) strategies before, during, and after crises might be used to respond to and mitigate the hazards. Preparation plans before the crisis are almost the most effective intervention. However, “during” and “after” crises need considerable steps of RCCE-IM as well. Listening to the concerns of the vulnerable populations, avoiding discriminatory language, providing correct and timely information, using effective communication strategies, using tools to build resilience, and engaging with the community should be built and/or strengthened among the vulnerable groups.

Conclusions
Addressing structural vulnerabilities with public and global health perspective might provide us with more sustainable and efficient solutions. In this presentation, answers will be provided on how to use RCCE-IM strategies in structural vulnerability and the strengths and weaknesses of the system with the proposed solutions based on the global situation.