bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of broad spectrum mycosporine loaded sunscreen formulation from Ulva fasciata delile
Authors: Bhatia Saurabh , Sardana Satish , Sharma Ajay , Vargas De La Cruz Celia Bertha , Chaugule Bhupal , Khodaie Laleh 
Published: August 2019

Ba.ckground: Sunscreen formulations primarily offer protection against UV induced damages however nowadays it also maintains skin natural physiological conditions. Current global market is flooded with numerous sunscreen products which offer protection to skin against several UV induced damages. However most of these sunscreen formulations offers narrow spectrum protection against UV and also suffer from stability as well as toxicity related issues.
Methods: Present work aims to isolate mycosporine amino acid (Mgy) from green alga namely Ulva fasciata (U. fasciata) and study its sunscreen potential against widely used domestic marketed formulation. Stability evaluations were also performed for almost 90 days.
Results: Results demonstrated that the isolated compound, mycosporine glycine (Mgy) preserved physicochemical properties of the product and offered good stability for all formulations throughout the experimental period. Furthermore, Mgy loaded carbopol gel showed better sunscreen protection against marketed formulation in a concentration dependent manner. (7.709).
Conclusion: (6.806) Novel Myg loaded gel was proved to demonstrate several quality characteristics that may unlock new prospects for the production of more efficient, safe, and economic skin-care products.
Awareness on breast cancer screening in Malaysia: a cross sectional study
Authors: Lee Mun-Seng , ‘Azmiyaty Amar Ma’ ruf Choiriyatul , Nadhirah Izhar Dayang Puteri , Nafisah Ishak Sayyida , Wan Jamaluddin Wan Syazana , Ya’acob Syafiqah Nadiah Mohd , Kamaluddin Muhammad Nazrullah 
Published: August 2019

Introduction: The increasing rate of breast cancer (BC) incidence in Malaysia hints a lack of awareness among Malaysians. One (1) woman out of nineteen (19) is at risk with BC and almost up to fifty percent (50%) of women diagnosed with BC were reported to be under the age of fifty (50). Our main concern is to study the level of awareness among the women on risk factors, clinical manifestations, diagnosis, preventions and treatments.
Method: A cross-sectional study was conducted exclusively among women in the public with total sample of three hundred and forty six (346), questionnaires were distributed using a simple random technique. Data was collected and analyzed by student T test in SPPS version 20.
Results: Our study reveals insufficient awareness on BC. Overall, awareness on risk factors is inadequate, but good knowledge on the importance of family history and diet as risk factors are discovered. Awareness on the cause and clinical manifestations of BC is required for improvement. As for treatment, alternatives especially surgery and chemotherapy are unclear to public, public is remotely unwitting on cessation of smoking to prevent BC at the early stage.
Conclusion: Malaysian has spaces for improvement on awareness of BC in terms of risk factors, clinical manifestations, diagnosis, treatment and prevention. Early detection can be achieved with good awareness because it leads to better prognosis and lower mortality.
Was tun bei akutem Thoraxschmerz?
Authors: Haring Bernhard , Schmidt Alexander , Frantz Stefan 
Published: August 2019

AbstractAcute chest pain is one of the most important cardinal symptoms in medicine. There are several important differential diagnoses for chest pain. Therefore, a thorough history and physical examination, as well as the 12-lead ECG and laboratory tests are crucial. In clinical practice, it is useful to distinguish between cardiac chest pain and other forms of chest pain in order to treat patients appropriately and to exclude potentially life-threatening conditions.
Vorsorgeuntersuchungen und Check-ups in der Kardiologie
Authors: Rudolph Ulrike , Laufs Ulrich 
Published: August 2019

AbstractCardiovascular diseases (CVD), especially coronary artery disease (CAD), are the leading causes of morbidity and mortality worldwide. Elimination of modifiable risk factors has the potential to prevent up to 80 % of CVD. Therefore, disease prevention is based on the assessment of individual total CVD risk by using risk scores such as SCORE-algorithm that include the known main cardiovascular risk factors such as age, sex, smoking status, arterial hypertension und cholesterol.
Autopneumonektomie. Ein vergessenes Krankheitsbild
Authors: Gerhardy Hanno Julian , Weber Rene , Lux Philipp , Klein Rolf Michael , Winter Joachim 
Published: August 2019

Zusammenfassung
Anamnese Die 80-jährige Patientin stellte sich mit einer Arteria-carotis-Stenose links vor. Im Alter von 7 Jahren hatte sie unter Hämoptysen gelitten.
Untersuchungen und Diagnose Das EKG zeigte einen AV-Block II. Grades Typ Mobitz. Im Röntgenbild und Computertomogramm des Thorax imponierten eine Verlagerung des Mediastinums und des Herzens nach links, eine komplette Schrumpfung der linken Lunge, sowie eine Überblähung der rechten Lunge. Die Lungenfunktionsanalyse ergab eine mäßige Restriktion. Es wurde die Diagnose Autopneumonektomie gestellt.
Therapie und Verlauf Eine Schrittmacherimplantation über die linke V. cephalica und eine Endarteriektomie der Arteria carotis links wurden komplikationslos durchgeführt.
Folgerung Resultiert nach Autopneumonektomie eine Obstruktion der Atemwege aufgrund der Mediastinalverschiebung, ist eine operative Revision erforderlich. Eine Antibiotikatherapie ist bei Atemwegsinfektionen indiziert. Punktionen der V. subclavia sind kontraindiziert, da eine Fehlpunktion zu einem kompletten Pneumothorax führen kann.
Refluxdiagnostik – Stellenwert des Miktionszystourethrogramms
Authors: Beetz Rolf 
Published: August 2019

ZusammenfassungDas radiologische Miktionszystourethrogramm gilt in der Kinderurologie seit Langem als Goldstandard zur Refluxprüfung. In den zurückliegenden Jahrzehnten haben sich daneben zusätzliche kontrastmittelgestützte Verfahren wie die sonografische Refluxprüfung oder die Radionuklidzystografie etabliert. Ihr Hauptindikationsgebiet liegt in der Reflux-Diagnostik nach Pyelonephritis im Säuglings- und Kindesalter. Für die Auswahl der geeigneten Methode spielen klinische Fragestellung, Verfügbarkeit, ökonomische Aspekte, personeller und zeitlicher Aufwand und das Ziel der geringstmöglichen Strahlenbelastung bei maximalem Informationsgehalt eine Rolle. Moderne Strategien streben unabhängig von der Methode der Refluxprüfung eine risikoorientierte, individuelle Indikationsstellung an.
Pharmacological prophylaxis versus pancreatic duct stenting plus pharmacological prophylaxis for prevention of post-ERCP pancreatitis in high risk patients: a randomized trial
Authors: Sotoudehmanesh Rasoul , Ali-Asgari Ali , Khatibian Morteza , Mohamadnejad Mehdi , Merat Shahin , Sadeghi Anahita , Keshtkar Abbas , Bagheri Mohammad , Delavari Alireza , Amani Mohammad , Vahedi Homayoon , Nasseri-Moghaddam Siavosh , Sima Alireza , Eloubeidi Mohamad A. , Malekzadeh Reza 
Published: August 2019

Abstract
Background Acute pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ERCP). The aim of this noninferiority study was to evaluate the effectiveness of pancreatic duct (PD) stenting plus pharmacological prophylaxis vs. pharmacological prophylaxis alone in the prevention of post-ERCP pancreatitis (PEP) in high risk patients.
Methods In this randomized, controlled, double-blind, noninferiority trial, patients at high risk of developing PEP were randomly allocated to pharmacological prophylaxis (rectal indomethacin, sublingual isosorbide dinitrate, and intravenous hydration with Ringer’s lactate) plus PD stenting (group A) or pharmacological prophylaxis alone (group B). The rate and severity of PEP, serum amylase levels, and length of hospital stay after ERCP were assessed.
Results During 21 months, a total of 414 patients (mean age 55.5 ± 17.0 years; 60.2 % female) were enrolled (207 in each group). PEP occurred in 59 patients (14.3 %, 95 % confidence interval [CI] 11.1 % – 17.9 %: 26 patients [12.6 %, 95 %CI 8.6 % – 17.6 %] in group A and 33 [15.9 %, 95 %CI 11.4 % – 21.4 %] in group B). There was no significant difference between the two groups in PEP severity (P = 0.59), amylase levels after 2 hours (P = 0.31) or 24 hours (P = 0.08), and length of hospital stay (P = 0.07).
Conclusions The study failed to demonstrate noninferiority or inferiority of pharmacological prophylaxis alone compared with PD stenting plus pharmacological prophylaxis in the prevention of PEP in high risk patients.
Homeopathic Potencies May Possess an Electric Field(-like) Component: Evidence from the Use of Encapsulated Solvatochromic Dyes
Authors: Cartwright Steven J. 
Published: August 2019

Background Homeopathic potencies have been shown to interact with a range of solvatochromic dyes to produce spectroscopic changes in the visible region of the electromagnetic spectrum. Furthermore, the nature of the changes observed under different experimental conditions is beginning to limit the number of possible hypotheses that can be put forward regarding the fundamental identity of potencies.
Aims and Methods The present study uses β-cyclodextrins to encapsulate solvatochromic dyes of widely varying structures. The purpose of this approach is to de-couple the primary dye–potency interaction from any subsequent aggregation effects.
Results Despite large differences in molecular structure between dyes, results show that potencies affect all dyes according to the same fundamental principles. Specifically, positively and negatively solvatochromic dyes collectively respond in opposite and complementary ways to potencies in accordance with the differential stabilisation of their excited and ground electronic states. Under the conditions of encapsulation, positively solvatochromic dyes display a bathochromic shift of, on average, 0.4 nm with a 2% absorbance change, and negatively solvatochromic dyes display a hypsochromic shift of, on average, 0.2 nm with a 1% absorbance change. This behaviour is only ever seen in two situations—where solvent becomes more polar or where an electric field is applied to solutions of dyes.
Conclusions The conditions used in this and previous studies to investigate the interaction of potencies with solvatochromic dyes preclude increased polarity of solvent as being responsible for the observed effects and that an explanation in which potencies carry an electric field (or electric field-like) component is by far the more likely. From the magnitude of the spectral changes induced in the dye Brooker's merocyanine by Arsenicum 10M, an estimate of the strength of the postulated electric field of 1.16 × 107 V/m can be made, which is comparable with the potential difference across cell membranes.
Interventional Oncology for Hepatic Malignancy in Children
Authors: Koo Kevin S. H. , Lungren Matthew P. , Aguado Allison 
Published: August 2019

AbstractThe field of interventional radiology has become an integral contributor in the multidisciplinary oncological treatment of numerous solid tumors in the adult population, especially hepatic malignancies. With continued growth and sophistication in the field of pediatric interventional radiology, interventional oncology (IO) principles and techniques are increasingly applied to children. While primary pediatric hepatic malignancies are less frequent than in the adult population, application of these IO principles and modalities in adults is becoming more commonplace. This article reviews the increasing application of these IO principles and modalities for the treatment of primary pediatric hepatic malignancy, as well as their role in the multidisciplinary care of children afflicted with these diseases.
Delayed Cerebral Metastasis of Breast Cancer: Case Report and Molecular Review
Authors: Olijnyk Leonardo Dessesards , Morais Artur Nobrega Lima , Carvalho Rodolfo Figueiredo , Abrão Adriana , Patel Krunal , Silva Carlos Eduardo 
Published: August 2019

AbstractBreast cancer (BC) is a prevalent disease, and its incidence of brain metastasis (BM) varies from 5 to 30% according to the literature. We present the case of a delayed isolated cerebral metastasis in a female patient following a period of 16 years after the diagnosis and first treatment. During this time, there was no other recurrence. We also review the literature concerning central nervous system spread and the molecular subtypes of such late tumors.
Air-Drying: A Simple Method for the Preservation of Hollow Organs and Lungs to Contribute to the Teaching of Anatomy
Authors: Abumandour Mohamed Mohamed Abd El-Rahman , El-Bakery Raafat Mohamed Ahmed 
Published: August 2019

AbstractThe present study describes air-drying, which is an alternative method to study and teach gross anatomy to undergraduate and postgraduate students. In order to preserve the hollow organs of different animals, an air-drying pump (compressor) was used; then, the preserved specimens were expanded through the injection of foam into their lumen followed by the application of varnish on their external surface to protect them from insect damage. This method of preservation is suitable for developing countries because it is cheap to prepare, simple to perform, and can be performed at room temperature (37°-40°C) without special equipment. The produced specimens have many advantages: their normal anatomical form remains durable, very light in weight, non- toxic regarding handling, and resistant to improper handling and deterioration by fungi or bacteria, with all structures very clear. These preserved specimens last for many years without any changes.
Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis
Authors: Ashouri Judith F. , Hsu Lih-Yun , Yu Steven , Rychkov Dmitry , Chen Yiling , Cheng Debra A. , Sirota Marina , Hansen Erik , Lattanza Lisa , Zikherman Julie , Weiss Arthur 
Published: August 2019

SignificanceHow arthritis-causing T cells trigger rheumatoid arthritis (RA) is not understood since it is difficult to differentiate T cells activated by inflammation in arthritic joints from those activated through their T cell antigen receptor (TCR) by self-antigens. We developed a model to identify and study antigen-specific T cell responses in arthritis. Nur77—a specific marker of TCR signaling—was used to identify antigen-activated T cells in the SKG arthritis model and in patients with RA. Nur77 could distinguish highly arthritogenic and autoreactive T cells in SKG mice. The enhanced autoreactivity was associated with increased interleukin-6 (IL-6) receptor signaling, likely contributing to their arthritogenicity. These data highlight a functional correlate between Nur77 expression, arthritogenic T cell populations, and heightened IL-6 sensitivity in SKG mice with translatable implications for human RA.
The Influence of Groundwater Basin Existence Towards The Urban Development In Java
Authors: Sukmawati D P , Buchori I , Firmanasari R 
Published: August 2019

Abstract
Groundwater is one of natural water resource that most commonly used to support the human activity. It plays an important role in shaping both physical and non-physical urban development aspect. The different availability of groundwater supply could lead into the different development rates of each area, especially in Java. The correlation between the existence of groundwater basin (CAT) and its influence to urban development could be used as base consideration to propose the development typology. Defining development typologies and what variable could distinct the developments in CAT and non-CAT area using discriminant analysis and remote sensing approach. Furthermore, there are three stages need to observe, i.e.: identify urban-rural area delineation change, defines development rates, and the last is defining discriminate variable which have significantly different means across the urban development in CAT and Non-CAT area. The observation reveals that in order to find the correlation between CAT existence and development rate, the eight-development typology has been establish. The typology is conduct regard to the development rate that categorizes in zero growth, slow growth, moderate growth, and fast growth both in CAT and Non-CAT. While, according to the result of discriminant analysis there are six variables that could distinct the urban developments in CAT and non-CAT, i.e.: proportion of dry land farm, status area, wet-land farm, built up area, agricultural household, and road density.
School Route Mapping in Semarang
Authors: Dewi D I K , Khadiyanto P , Kurniati R , Zulhamdi  
Published: August 2019

Abstract
This paper aims to examines some routes for children go in to school, so the route can lead their parents to choose a travel mode for their children to go to school. The methods used in this research is GIS mapping and spatial distribution analysis. This mapping route refers to parents where parents ussually take their children to school to be dominant, even for distance the school less than 1 km. This mapping attempts to promote walking and cycling to school for children based on the concentration of the location of the student’s residence with a range of distance from the school location less than 1000 meters or more than 1000 meters. Therefore, the mapping process can help the parents to make a decision for transportation modal choice.
Spatial Distribution on the search for economic externalities acquisition in rural industry clustering: A study of emerging batik industry clusters in lagging regions of Wonosobo Regency and Purworejo Regency, Indonesia
Authors: Nugroho P 
Published: August 2019

Abstract
Compared to advanced countries, industrial clustering phenomena in developing countries have experienced multifaceted forms and different directions. When the former have featured robustness and predictability of cluster performance, the latter has been struggling with messy institutional support for business continuation. Cluster existence in developing countries lacks capabilities to establish economic externalities of industrial agglomeration due to poor inter-industry linkages and business cooperation. In Indonesia context, the emergence of rural industry clustering addresses intriguing explorations on its resilience in coping with the unconducive business environment. This paper is aimed at examining the experience of the emerging batik industry clusters in lagging regions in response to a variety of obstacles in physical, social, economic, and institutional aspects. By using a sequential explanatory mixed-methods design, the study focuses on the formation of inter-industry linkages and business cooperation in the local batik industry clusters. Spatial distribution was analyzed using GIS. The preliminary conclusion suggests that the practice of rural industry clustering has merely demonstrated a trial-and-error opportunistic behaviour rather than a well-organised business milieu. The local government intervention to cluster formation has served as a temporary solution for small-and-medium enterprises development by utilising local resources and empowering village communities. For the long-term, such action may jeopardise the management of rural economies into ineffective burdens instead of promoting cluster competitiveness better.
Spatial Assessment of Slum Area in Jepara City from Physical and Non-Physical Aspects Perspective
Authors: Sunarti  , Esariti L , Haulah L 
Published: August 2019

Abstract
Slums are one of the main problems in almost urban areas, especially in coastal areas such as in Jepara. However, the issue has not been handled comprehensively, but only partially, focusing on the physical aspects of slums only. One of the problems that have not been resolved in some slums is related to the environmental and social aspects of society. But so far, the assessment of slums by the government is still dominated by the physical aspect. This study aims to analyse the spatial assessment of slums area in Jepara City by combining physical and non-physical problems approach. The mixed method approach is chosen as the method used to answer the research objectives. By collecting primary data, secondary data and map overlay for locations that are still categorized as slum. The results show that the assessment of slum settlements in Jepara is still limited because it has not been analyzed related to socio-economic aspects in depth. In addition, the role of institutions or local communities is not strong enough yet to support the slum upgrading program. In essence, the government needs to re-examine the important indicators that need to be prioritized in the assessment of slums, so that the action handling can be done properly and comprehensively.
Remote sensing and GIS applications for planning of sustainable food agriculture land and agricultural commodity development in Denpasar City
Authors: Lanya I , Subadiyasa N , Sardiana K , Ratna Adi G P 
Published: August 2019

Abstract
Denpasar as the provincial capital of Bali still has 2225 rice fields. Denpasar Regional Spatial Plan (SP) 2011-2031, paddy fields as Green Open Space (GOS) 1563 ha. GOS is intended for the preservation of agrarian culture, the balance of urban ecosystems, and agro-ecotourism. Preservation of resources and economic improvement of the area needs to be developed a data base of sustainable food agriculture land (SFAL) planning. SFAL from the results of spatial analysis of 10 thematic maps defined as GOS, the Subak region’s spatial data base from analysis of satellite images, and subak attribute data from the results of agroecosystem land suitability classification. Information on Subak resource potential using QGIS software version 2.18.0 through join attributes. SFAL/GOS paddy fields for SP years 2031-2050 = 1064.14 ha (47.83%), for SP more than 2050 = 695.09 ha (31.25%) from 2015 paddy fields. Paddy fields in North Denpasar and East Denpasar ± 80 % as SFAL/GOS, South Denpasar and West Denpasar 0%. Land suitability for lowland rice is 100% very suitable (S1), production increase is done through efforts to improve the availability of irrigation water and phosphor fertilization. Horticultural crops 80% potentially developed, with improved drainage, water availability and fertilization.
The motivations and dynamics of Zimbabwe’s 2017 military coup
Authors: Tendi Blessing-Miles 
Published: August 2019

ABSTRACT
Robert Mugabe resigned as Zimbabwe’s president in November 2017, following a military action called Operation Restore Legacy. This article examines the motivations and dynamics of Operation Restore Legacy, which it characterizes as a coup by military generals that had significant commonalities with historical coups in Africa. This characterization, which is informed by the accounts of coup participants and a reading of the literature, challenges interpretations of the coup as ‘a non-coup-coup’, ‘very Zimbabwean’, or ‘special’. The article argues that the coup was a vote of no confidence in Mugabe’s leadership, which succeeded because soldiers from Zimbabwe’s 1970s independence war subscribed to the coup’s stated ideal to restore liberation struggle principles in the ruling Zimbabwe African National Union Patriotic Front party as well as party members who had been sidelined. Liberation war veterans held decisive army and air force command posts when the coup occurred. The article’s emphasis on liberation struggle principles as a crucial determinant of the coup’s success is a counterpoint to game theoretic approaches to coup dynamics that disregard political beliefs as a consequential factor in the realization of coups. In respect of motivations, the article advances interrelating motives and contends that the coup’s catalyst was Mugabe’s refusal to meet his generals on 13 November 2017, for vital talks on widening differences between both parties. Sealing off dialogue catalyzed the coup.